Afterword: Considerations for Future Practice of Assessment and Accountability

ERIC Educational Resources Information Center

Bresciani, Marilee J.

2013-01-01

This afterword offers challenges and considerations as the assessment movement continues to develop. The author offers some simple considerations for readers to ponder as they advance their evidence-based decision making processes, and encourages others to use these methods within the context of recent neuroscientific evidence that learning and…

Parametric emittance measurements of electron beams produced by a laser plasma accelerator

NASA Astrophysics Data System (ADS)

Barber, S. K.; van Tilborg, J.; Schroeder, C. B.; Lehe, R.; Tsai, H.-E.; Swanson, K. K.; Steinke, S.; Nakamura, K.; Geddes, C. G. R.; Benedetti, C.; Esarey, E.; Leemans, W. P.

2018-05-01

Laser plasma accelerators (LPA) offer an exciting possibility to deliver high energy, high brightness electrons beams in drastically smaller distance scales than is typical for conventional accelerators. As such, LPAs draw considerable attention as potential drivers for next generation light sources and for a compact linear collider. In order to asses the viability of an LPA source for a particular application, the brightness of the source should be properly characterized. In this paper, we present charge dependent transverse emittance measurements of LPA sources using both ionization injection and shock induced density down ramp injection, with the latter delivering smaller transverse emittances by a factor of two when controlling for charge density. The single shot emittance method is described in detail with a discussion on limitations related to second order transport effects. The direct role of space charge is explored through a series of simulations and found to be consistent with experimental observations.

A place for marriage and family services in employee assistance programs (EAPs): a survey of EAP client problems and needs.

PubMed

Shumway, Sterling T; Wampler, Richard S; Dersch, Charette; Arredondo, Rudy

2004-01-01

Marriage and family services have not been widely recognized as part of employee assistance programs (EAP), although family and relational problems are widely cited as sources of problems on the job. EAP clients (N = 800, 97% self-referred) indicated how much family, psychological/emotional, drug, alcohol, employment-related, legal, and medical problems troubled them and the need for services in each area. Psychological/emotional (66%) and family (65%) problem areas frequently were rated "considerable" or "extreme." Both areas were rated as "considerable" or "extreme" by 48.6% of participants. In view of the evidence that marriage and family services can be effective with both family and psychological/emotional problems, professionals who are competent to provide such services have much to offer EAP programs.

Research on environmental impact of water-based fire extinguishing agents

NASA Astrophysics Data System (ADS)

Wang, Shuai

2018-02-01

This paper offers current status of application of water-based fire extinguishing agents, the environmental and research considerations of the need for the study of toxicity research. This paper also offers systematic review of test methods of toxicity and environmental impact of water-based fire extinguishing agents currently available, illustrate the main requirements and relevant test methods, and offer some research findings for future research considerations. The paper also offers limitations of current study.

Learning science as a potential new source of understanding and improvement for continuing education and continuing professional development.

PubMed

Van Hoof, Thomas J; Doyle, Terrence J

2018-01-15

Learning science is an emerging interdisciplinary field that offers educators key insights about what happens in the brain when learning occurs. In addition to explanations about the learning process, which includes memory and involves different parts of the brain, learning science offers effective strategies to inform the planning and implementation of activities and programs in continuing education and continuing professional development. This article provides a brief description of learning, including the three key steps of encoding, consolidation and retrieval. The article also introduces four major learning-science strategies, known as distributed learning, retrieval practice, interleaving, and elaboration, which share the importance of considerable practice. Finally, the article describes how learning science aligns with the general findings from the most recent synthesis of systematic reviews about the effectiveness of continuing medical education.

A determination of the mass of Sagittarius A* from its radio spectral and source size measurements

NASA Technical Reports Server (NTRS)

Melia, Fulvio; Jokipii, J. R.; Narayanan, Ajay

1992-01-01

There is growing evidence that Sgr A* may be a million solar mass black hole accreting from the Galactic center wind. A consideration of the spectral and source size characteristics associated with this process can offer at least two distinct means of inferring the mass M, complementing the more traditional dynamical arguments. We show that M is unmistakably correlated with both the radio spectral index and the critical wavelength below which the intrinsic source size dominates over the angular broadening due to scattering in the interstellar medium. Current observations can already rule out a mass much in excess of 2 x 10 exp 6 solar masses and suggest a likely value close to 1 x 10 exp 6 solar masses, in agreement with an earlier study matching the radio and high-energy spectral components. We anticipate that such a mass may be confirmed with the next generation of source-size observations using milliarcsecond angular resolution at 0.5 - 1 cm wavelengths.

Amateur Telescope Making

NASA Astrophysics Data System (ADS)

Tonkin, Stephen

Many amateur astronomers make their own instruments, either because of financial considerations or because they are just interested. Amateur Telescope Making offers a variety of designs for telescopes, mounts and drives which are suitable for the home-constructor. The designs range from simple to advanced, but all are within the range of a moderately well-equipped home workshop. The book not only tells the reader what he can construct, but also what it is sensible to construct given what time is available commercially. Thus each chapter begins with reasons for undertaking the project, then looks at theoretical consideration before finishing with practical instructions and advice. An indication is given as to the skills required for the various projects. Appendices list reputable sources of (mail order) materials and components. The telescopes and mounts range from "shoestring" (very cheap) instruments to specialist devices that are unavailable commercially.

Air quality considerations for stormwater green street design.

PubMed

Shaneyfelt, Kathryn M; Anderson, Andrew R; Kumar, Prashant; Hunt, William F

2017-12-01

Green streets are increasingly being used as a stormwater management strategy to mitigate stormwater runoff at its source while providing other environmental and societal benefits, including connecting pedestrians to the street. Simultaneously, human exposure to particulate matter from urban transportation is of major concern worldwide due to the proximity of pedestrians, drivers, and cyclists to the emission sources. Vegetation used for stormwater treatment can help designers limit the exposure of people to air pollutants. This goal can be achieved through the deliberate placement of green streets, along with strategic planting schemes that maximize pollutant dispersion. This communication presents general design considerations for green streets that combine stormwater management and air quality goals. There is currently limited guidance on designing green streets for air quality considerations; this is the first communication to offer suggestions and advice for the design of green stormwater streets in regards to their effects on air quality. Street characteristics including (1) the width to height ratio of the street to the buildings, (2) the type of trees and their location, and (3) any prevailing winds can have an impact on pollutant concentrations within the street and along sidewalks. Vegetation within stormwater control measures has the ability to reduce particulate matter concentrations; however, it must be carefully selected and placed within the green street to promote the dispersion of air flow. Copyright © 2017 Elsevier Ltd. All rights reserved.

Xenon gas field ion source from a single-atom tip

NASA Astrophysics Data System (ADS)

Lai, Wei-Chiao; Lin, Chun-Yueh; Chang, Wei-Tse; Li, Po-Chang; Fu, Tsu-Yi; Chang, Chia-Seng; Tsong, T. T.; Hwang, Ing-Shouh

2017-06-01

Focused ion beam (FIB) systems have become powerful diagnostic and modification tools for nanoscience and nanotechnology. Gas field ion sources (GFISs) built from atomic-size emitters offer the highest brightness among all ion sources and thus can improve the spatial resolution of FIB systems. Here we show that the Ir/W(111) single-atom tip (SAT) can emit high-brightness Xe+ ion beams with a high current stability. The ion emission current versus extraction voltage was analyzed from 150 K up to 309 K. The optimal emitter temperature for maximum Xe+ ion emission was ˜150 K and the reduced brightness at the Xe gas pressure of 1 × 10-4 torr is two to three orders of magnitude higher than that of a Ga liquid metal ion source, and four to five orders of magnitude higher than that of a Xe inductively coupled plasma ion source. Most surprisingly, the SAT emitter remained stable even when operated at 309 K. Even though the ion current decreased with increasing temperature, the current at room temperature (RT) could still reach over 1 pA when the gas pressure was higher than 1 × 10-3 torr, indicating the feasibility of RT-Xe-GFIS for application to FIB systems. The operation temperature of Xe-SAT-GFIS is considerably higher than the cryogenic temperature required for the helium ion microscope (HIM), which offers great technical advantages because only simple or no cooling schemes can be adopted. Thus, Xe-GFIS-FIB would be easy to implement and may become a powerful tool for nanoscale milling and secondary ion mass spectroscopy.

POST ASYMPTOTIC GIANT BRANCH BIPOLAR REFLECTION NEBULAE: RESULT OF DYNAMICAL EJECTION OR SELECTIVE ILLUMINATION?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koning, N.; Kwok, Sun; Steffen, W., E-mail: nico.koning@ucalgary.ca, E-mail: sunkwok@hku.hk, E-mail: wsteffen@astrosen.unam.mx

2013-03-10

A model for post asymptotic giant branch bipolar reflection nebulae has been constructed based on a pair of evacuated cavities in a spherical dust envelope. Many of the observed features of bipolar nebulae, including filled bipolar lobes, an equatorial torus, searchlight beams, and a bright central light source, can be reproduced. The effects on orientation and dust densities are studied and comparisons with some observed examples are offered. We suggest that many observed properties of bipolar nebulae are the result of optical effects and any physical modeling of these nebulae has to take these factors into consideration.

Assessing Procedural Competence: Validity Considerations.

PubMed

Pugh, Debra M; Wood, Timothy J; Boulet, John R

2015-10-01

Simulation-based medical education (SBME) offers opportunities for trainees to learn how to perform procedures and to be assessed in a safe environment. However, SBME research studies often lack robust evidence to support the validity of the interpretation of the results obtained from tools used to assess trainees' skills. The purpose of this paper is to describe how a validity framework can be applied when reporting and interpreting the results of a simulation-based assessment of skills related to performing procedures. The authors discuss various sources of validity evidence because they relate to SBME. A case study is presented.

Investigating the application of AOP methodology in development of Financial Accounting Software using Eclipse-AJDT Environment

NASA Astrophysics Data System (ADS)

Sharma, Amita; Sarangdevot, S. S.

2010-11-01

Aspect-Oriented Programming (AOP) methodology has been investigated in development of real world business application software—Financial Accounting Software. Eclipse-AJDT environment has been used as open source enhanced IDE support for programming in AOP language—Aspect J. Crosscutting concerns have been identified and modularized as aspects. This reduces the complexity of the design considerably due to elimination of code scattering and tangling. Improvement in modularity, quality and performance is achieved. The study concludes that AOP methodology in Eclipse-AJDT environment offers powerful support for modular design and implementation of real world quality business software.

Internet and social network recruitment: two case studies.

PubMed

Johnson, Kathy A; Peace, Jane

2012-01-01

The recruitment of study participants is a significant research challenge. The Internet, with its ability to reach large numbers of people in networks connected by email, Facebook and other social networking mechanisms, appears to offer new avenues for recruitment. This paper reports recruitment experiences from two research projects that engaged the Internet and social networks in different ways for study recruitment. Drawing from the non-Internet recruitment literature, we speculate that the relationship with the source of the research and the purpose of the engaged social network should be a consideration in Internet or social network recruitment strategies.

The confusing world of dietary sugars: definitions, intakes, food sources and international dietary recommendations.

PubMed

Hess, Jennifer; Latulippe, Marie E; Ayoob, Keith; Slavin, Joanne

2012-05-01

Government and health organizations worldwide have issued dietary guidelines for sugars. These guidelines vary considerably in the recommended or suggested intakes and the types of sugars specified. Despite access to the same published literature, recommendations vary greatly and create confusion for nutrition practitioners who offer dietary guidance. Some of the confusion in this field is linked to differences in definitions for sugar and methods to measure total sugars. Additionally, although dietary guidance typically recommends foods high in sugar, fruits and dairy products, other advice suggests strict limits on intake of "added sugar". Added sugar cannot be analytically determined and must be calculated so nutrient databases generally contain values for total sugar and do not differentiate between sugars naturally occurring in foods and those added in processing. This review defines sugars, provides the sugar content of major food sources, summarizes health concerns about dietary sugars, and compiles dietary guidelines for sugars issued by various organizations. Dietary recommendations from various health organizations are based on different means of assessment, and thus vary considerably. In general, the use of added sugars is cautioned, especially when it contributes to calories in excess of needs for an individual.

Tapping Into Water: Key Considerations for Achieving Excellence in School Drinking Water Access

PubMed Central

Hecht, Kenneth; Hampton, Karla E.; Grumbach, Jacob M.; Braff-Guajardo, Ellen; Brindis, Claire D.

2014-01-01

Objectives. We examined free drinking water access in schools. Methods. We conducted cross-sectional interviews with administrators from 240 California public schools from May to November 2011 to examine the proportion of schools that met excellent water access criteria (i.e., location, density, type, maintenance, and appeal of water sources), school-level characteristics associated with excellent water access, and barriers to improvements. Results. No schools met all criteria for excellent water access. High schools and middle schools had lower fountain:student ratios than elementary schools (odds ratio [OR] = 0.06; 95% confidence interval [CI] = 0.02, 0.20; OR = 0.30, 95% CI = 0.12, 0.70). Rural schools were more likely to offer a nonfountain water source than city schools (OR = 5.0; 95% CI = 1.74, 14.70). Newer schools were more likely to maintain water sources than older schools (OR = 0.98; 95% CI = 0.97, 1.00). Schools that offered free water in food service areas increased from pre- to postimplementation of California’s school water policy (72%–83%; P < .048). Barriers to improving school water included cost of programs and other pressing concerns. Conclusions. Awareness of the benefits related to school drinking water provision and funding may help communities achieve excellence in drinking water access. PMID:24832141

Conflicts and dilemmas in prevention of cardiovascular disease. The new, Norwegian guidelines--a new approach to risk management.

PubMed

Gjelsvik, Bjørn

2012-03-01

Prevention of cardiovascular disease (CVD) has been debated for many years, between an organ-specialist perspective versus a public health view. As an illustration, the Wonca Europe Council decided in 2004 to withdraw its support to the 2003 European Guidelines. This paper discusses the main sources of disagreement, most important the levels of risk when treatment should be offered. The Norwegian Guideline for primary prevention of CVD (2009) introduced a new principle of age-differentiated risk levels. Pharmacological treatment should be offered to all persons aged 40-49 years with 10-year mortality risk ≥ 1%, all persons aged 50-59 years at ≥ 5% risk, and all persons aged 60-69 years at ≥ 10% risk. Lower thresholds for younger persons are based on the fact that life years lost, will be considerable if drugs are prescribed only for risk levels above 5%. For persons aged 60-69 years, age is the dominant risk factor and the benefits of treatment are smaller. The implications of the recommendation are discussed, both at an individual and a societal level. Compared to the European 2007 guidelines, the total sum of life years gained is about the same, but the number of patients treated is considerably lower.

Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells

NASA Astrophysics Data System (ADS)

Zalzman, Michal; Gupta, Sanjeev; Giri, Ranjit K.; Berkovich, Irina; Sappal, Baljit S.; Karnieli, Ohad; Zern, Mark A.; Fleischer, Norman; Efrat, Shimon

2003-06-01

Beta-cell replacement is considered to be the most promising approach for treatment of type 1 diabetes. Its application on a large scale is hindered by a shortage of cells for transplantation. Activation of insulin expression, storage, and regulated secretion in stem/progenitor cells offers novel ways to overcome this shortage. We explored whether fetal human progenitor liver cells (FH) could be induced to differentiate into insulin-producing cells after expression of the pancreatic duodenal homeobox 1 (Pdx1) gene, which is a key regulator of pancreatic development and insulin expression in beta cells. FH cells possess a considerable replication capacity, and this was further extended by introduction of the gene for the catalytic subunit of human telomerase. Immortalized FH cells expressing Pdx1 activated multiple beta-cell genes, produced and stored considerable amounts of insulin, and released insulin in a regulated manner in response to glucose. When transplanted into hyperglycemic immunodeficient mice, the cells restored and maintained euglycemia for prolonged periods. Quantitation of human C-peptide in the mouse serum confirmed that the glycemia was normalized by the transplanted human cells. This approach offers the potential of a novel source of cells for transplantation into patients with type 1 diabetes.

Extending FDA guidance to include consumer medication information (CMI) delivery on mobile devices.

PubMed

Sage, Adam; Blalock, Susan J; Carpenter, Delesha

This paper describes the current state of consumer-focused mobile health application use and the current U.S. Food and Drug Administration (FDA) guidance on the distribution of consumer medication information (CMI), and discusses recommendations and considerations for the FDA to expand CMI guidance to include CMI in mobile applications. Smartphone-based health interventions have been linked to increased medication adherence and improved health outcomes. Trends in smartphone ownership present opportunities to more effectively communicate and disseminate medication information; however, current FDA guidance for CMI does not outline how to effectively communicate CMI on a mobile platform, particularly in regards to user-centered design and information sourcing. As evidence supporting the potential effectiveness of mobile communication in health care continues to increase, CMI developers, regulating entities, and researchers should take note. Although mobile-based CMI offers an innovative mechanism to deliver medication information, caution should be exercised. Specifically, considerations for developing mobile CMI include consumers' digital literacy, user experience (e.g., usability), and the quality and accuracy of new widely used sources of information (e.g., crowd-sourced reviews and ratings). Recommended changes to FDA guidance for CMI include altering the language about scientific accuracy to address more novel methods of information gathering (e.g., anecdotal experiences and Google Consumer Surveys) and including guidance for usability testing of mobile health applications. Copyright © 2016 Elsevier Inc. All rights reserved.

Abnormal emotion processing, but intact fairness and intentionality considerations during social decision-making in schizophrenia.

PubMed

de la Asuncion, Javier; Docx, Lise; Sabbe, Bernard; Morrens, Manuel; de Bruijn, Ellen R A

2015-01-01

Schizophrenia is a severe mental disorder that is highly characterized by social cognitive impairments. Most studies investigating these impairments focus on one specific social domain such as emotion recognition. However, in daily life, processing complex social situations relies on the combination of several social cognitive and affective processes simultaneously rather than one process alone. A modified version of the economically based Ultimatum Game was used to measure the interplay between fairness, intentionality, and emotion considerations during social decision-making. In this task, participants accept or reject fair and unfair monetary offers proposed intentionally or unintentionally by either angry, happy, neutral, or sad proposers. Behavioral data was collected from a group of schizophrenia patients (N = 35) and a group of healthy individuals (N = 30). Like healthy participants, schizophrenia patients differentiated between fair and unfair offers by rejecting unfair offers more compared to fair offers. However, overall patients did reject more fair offers, indicating that their construct of fairness operates within different margins. In both groups, intentional unfair offers were rejected more compared to unintentional ones, indicating a normal integration of intentionality considerations in schizophrenia. Importantly, healthy subjects also differentiated between proposers' emotion when rejecting unfair offers (more rejections from proposers depicting angry faces compared to proposers depicting, happy, neutral, or sad faces). Schizophrenia patients' decision behavior on the other hand, was not affected by the proposers' emotions. The current study thus shows that schizophrenia patients have specific problems with processing and integrating emotional information. Importantly, the finding that patients display normal fairness and intentionality considerations emphasizes preservation of central social cognitive processes in schizophrenia.

17 CFR 230.251 - Scope of exemption.

Code of Federal Regulations, 2010 CFR

2010-04-01

... consideration must be reasonable at the time made. (c) Integration with other offerings. Offers and sales made... dealers with reasonable quantities of the offering circular for this purpose. (3) Continuous or delayed offerings. Continuous or delayed offerings may be made under this Regulation A if permitted by § 230.415. ...

Counterfactual comparison modulates fairness consideration in the mini-ultimatum game: an event-related potentials study.

PubMed

Liang, Jiafeng; Lin, Huiyan; Xiang, Jing; Wu, Hao; Li, Xu; Liang, Hongyu; Zheng, Xue

2015-04-01

Existing literature on the mini-ultimatum game indicates that counterfactual comparison between chosen and unchosen alternatives is of great importance for individual's fairness consideration. However, it is still unclear how counterfactual comparison influences the electrophysiological responses to unfair chosen offers. In conjunction with event-related potentials' (ERPs) technique, the current study aimed to explore the issue by employing a modified version of the mini-ultimatum game where a fixed set of two alternatives (unfair offer vs. fair alternative, unfair vs. hyperfair alternative, unfair offer vs. hyperunfair alternative) was presented before the chosen offer. The behavioral results showed that participants were more likely to accept unfair chosen offers when the unchosen alternative was hyperunfair than when the unchosen alternative was fair or hyperfair. The ERPs results showed that the feedback-related negativity (FRN) elicited by unfair chosen offers was insensitive to the type of unchosen alternative when correcting for possible overlap with other components. In contrast, unfair chosen offers elicited larger P300 amplitudes when the unchosen alternative was hyperunfair than when the unchosen alternative was fair or hyperfair. These findings suggest that counterfactual comparison may take effect at later stages of fairness consideration as reflected by the P300. © 2015 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

Isotope effect of mercury diffusion in air

PubMed Central

Koster van Groos, Paul G.; Esser, Bradley K.; Williams, Ross W.; Hunt, James R.

2014-01-01

Identifying and reducing impacts from mercury sources in the environment remains a considerable challenge and requires process based models to quantify mercury stocks and flows. The stable isotope composition of mercury in environmental samples can help address this challenge by serving as a tracer of specific sources and processes. Mercury isotope variations are small and result only from isotope fractionation during transport, equilibrium, and transformation processes. Because these processes occur in both industrial and environmental settings, knowledge of their associated isotope effects is required to interpret mercury isotope data. To improve the mechanistic modeling of mercury isotope effects during gas phase diffusion, an experimental program tested the applicability of kinetic gas theory. Gas-phase elemental mercury diffusion through small bore needles from finite sources demonstrated mass dependent diffusivities leading to isotope fractionation described by a Rayleigh distillation model. The measured relative atomic diffusivities among mercury isotopes in air are large and in agreement with kinetic gas theory. Mercury diffusion in air offers a reasonable explanation of recent field results reported in the literature. PMID:24364380

Convenient yet not a convenience sample: Jury pools as experimental subject pools.

PubMed

Murray, Gregg R; Rugeley, Cynthia R; Mitchell, Dona-Gene; Mondak, Jeffery J

2013-01-01

Scholars greatly benefit from access to convenient, inexpensive data sources. Many researchers rely on student subject pools, a practice that raises concern about the "college sophomore problem," or the possibility that findings from student subjects do not generalize beyond the campus. As an accessible, low cost, and heterogeneous data source, some researchers have used subjects recruited from jury pools, which are drawn from randomly-selected citizens required by law to appear for jury duty. In this paper, we discuss the strengths and weaknesses of this approach. First, we review pragmatic considerations involving access to jury pools, substantive content, the administration of survey-experiments, and the financial costs and benefits of this approach. Next, we present evidence regarding the quality of jury pool samples in terms of response rates, diversity, and representativeness. We conclude that jury pools, given proper attention to their limitations, offer an attractive addition to the viable sources of experimental data. Copyright © 2012 Elsevier Inc. All rights reserved.

Isotope effect of mercury diffusion in air.

PubMed

Koster van Groos, Paul G; Esser, Bradley K; Williams, Ross W; Hunt, James R

2014-01-01

Identifying and reducing impacts from mercury sources in the environment remains a considerable challenge and requires process based models to quantify mercury stocks and flows. The stable isotope composition of mercury in environmental samples can help address this challenge by serving as a tracer of specific sources and processes. Mercury isotope variations are small and result only from isotope fractionation during transport, equilibrium, and transformation processes. Because these processes occur in both industrial and environmental settings, knowledge of their associated isotope effects is required to interpret mercury isotope data. To improve the mechanistic modeling of mercury isotope effects during gas phase diffusion, an experimental program tested the applicability of kinetic gas theory. Gas-phase elemental mercury diffusion through small bore needles from finite sources demonstrated mass dependent diffusivities leading to isotope fractionation described by a Rayleigh distillation model. The measured relative atomic diffusivities among mercury isotopes in air are large and in agreement with kinetic gas theory. Mercury diffusion in air offers a reasonable explanation of recent field results reported in the literature.

7 CFR 1494.501 - Submission of offers to CCC.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Submission of offers to CCC. 1494.501 Section 1494... Program Operations § 1494.501 Submission of offers to CCC. (a) Consideration of offers. Unless otherwise specified in the Invitation, CCC will consider offers on a daily basis from the date of issuance of the...

7 CFR 1494.501 - Submission of offers to CCC.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Submission of offers to CCC. 1494.501 Section 1494....501 Submission of offers to CCC. (a) Consideration of offers. Unless otherwise specified in the Invitation, CCC will consider offers on a daily basis from the date of issuance of the Invitation until such...

7 CFR 1494.501 - Submission of offers to CCC.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Submission of offers to CCC. 1494.501 Section 1494....501 Submission of offers to CCC. (a) Consideration of offers. Unless otherwise specified in the Invitation, CCC will consider offers on a daily basis from the date of issuance of the Invitation until such...

7 CFR 1494.501 - Submission of offers to CCC.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Submission of offers to CCC. 1494.501 Section 1494....501 Submission of offers to CCC. (a) Consideration of offers. Unless otherwise specified in the Invitation, CCC will consider offers on a daily basis from the date of issuance of the Invitation until such...

7 CFR 1494.501 - Submission of offers to CCC.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Submission of offers to CCC. 1494.501 Section 1494... Program Operations § 1494.501 Submission of offers to CCC. (a) Consideration of offers. Unless otherwise specified in the Invitation, CCC will consider offers on a daily basis from the date of issuance of the...

17 CFR 229.1007 - (Item 1007) Source and amount of funds or other consideration.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false (Item 1007) Source and amount... Acquisitions (Regulation M-A) § 229.1007 (Item 1007) Source and amount of funds or other consideration. (a) Source of funds. State the specific sources and total amount of funds or other consideration to be used...

Controlled activation of retrotransposition for plant breeding.

PubMed

Paszkowski, Jerzy

2015-04-01

Plant genomes consist to a large extent of transposable elements (TEs), predominantly retrotransposons. Their accumulation through periodic transposition bursts has shaped the structure and regulatory organization of plant genomes, often contributing to phenotypic traits. Transposon-generated phenotypes selected by humans during plant domestication have been maintained under strict selection during subsequent plant breeding. Our knowledge of the epigenetic, environmental, and developmental regulation of TE activity has advanced considerably in recent years. Here I will consider TEs as an attractive endogenous source of genetic variation that can be liberated in a controlled fashion and thus offer novel phenotypic diversity to be selected for crop improvement. Copyright © 2015 Elsevier Ltd. All rights reserved.

Abnormal emotion processing, but intact fairness and intentionality considerations during social decision-making in schizophrenia

PubMed Central

de la Asuncion, Javier; Docx, Lise; Sabbe, Bernard; Morrens, Manuel; de Bruijn, Ellen R. A.

2015-01-01

Schizophrenia is a severe mental disorder that is highly characterized by social cognitive impairments. Most studies investigating these impairments focus on one specific social domain such as emotion recognition. However, in daily life, processing complex social situations relies on the combination of several social cognitive and affective processes simultaneously rather than one process alone. A modified version of the economically based Ultimatum Game was used to measure the interplay between fairness, intentionality, and emotion considerations during social decision-making. In this task, participants accept or reject fair and unfair monetary offers proposed intentionally or unintentionally by either angry, happy, neutral, or sad proposers. Behavioral data was collected from a group of schizophrenia patients (N = 35) and a group of healthy individuals (N = 30). Like healthy participants, schizophrenia patients differentiated between fair and unfair offers by rejecting unfair offers more compared to fair offers. However, overall patients did reject more fair offers, indicating that their construct of fairness operates within different margins. In both groups, intentional unfair offers were rejected more compared to unintentional ones, indicating a normal integration of intentionality considerations in schizophrenia. Importantly, healthy subjects also differentiated between proposers’ emotion when rejecting unfair offers (more rejections from proposers depicting angry faces compared to proposers depicting, happy, neutral, or sad faces). Schizophrenia patients’ decision behavior on the other hand, was not affected by the proposers’ emotions. The current study thus shows that schizophrenia patients have specific problems with processing and integrating emotional information. Importantly, the finding that patients display normal fairness and intentionality considerations emphasizes preservation of central social cognitive processes in schizophrenia. PMID:26257699

A capital idea. Bonds and nontraditional financing options.

PubMed

Wareham, Therese L

2004-05-01

Not-for-profit healthcare organizations have four basic sources of capital: internal sources, philanthropy, asset sales, and external sources. External sources, in particular, offer a wealth of options that are important for such organizations--especially those facing significant capital shortfalls--to consider. External sources include bond offerings and nontraditional offerings, such as receivables financing, off-balance-sheet options, real estate investment trusts, and subordinated securities.

Gravitational Radiation of a Vibrating Physical String as a Model for the Gravitational Emission of an Astrophysical Plasma

NASA Astrophysics Data System (ADS)

Lewis, Ray A.; Modanese, Giovanni

Vibrating media offer an important testing ground for reconciling conflicts between General Relativity, Quantum Mechanics and other branches of physics. For sources like a Weber bar, the standard covariant formalism for elastic bodies can be applied. The vibrating string, however, is a source of gravitational waves which requires novel computational techniques, based on the explicit construction of a conserved and renormalized energy-momentum tensor. Renormalization (in a classical sense) is necessary to take into account the effect of external constraints, which affect the emission considerably. Our computation also relaxes usual simplifying assumptions like far-field approximation, spherical or plane wave symmetry, TT gauge and absence of internal interference. In a further step towards unification, the method is then adapted to give the radiation field of a transversal Alfven wave in a rarefied astrophysical plasma, where the tension is produced by an external static magnetic field.

Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source

PubMed Central

Reddy, Hemanth K.N.; Yoon, Chun Hong; Aquila, Andrew; Awel, Salah; Ayyer, Kartik; Barty, Anton; Berntsen, Peter; Bielecki, Johan; Bobkov, Sergey; Bucher, Maximilian; Carini, Gabriella A.; Carron, Sebastian; Chapman, Henry; Daurer, Benedikt; DeMirci, Hasan; Ekeberg, Tomas; Fromme, Petra; Hajdu, Janos; Hanke, Max Felix; Hart, Philip; Hogue, Brenda G.; Hosseinizadeh, Ahmad; Kim, Yoonhee; Kirian, Richard A.; Kurta, Ruslan P.; Larsson, Daniel S.D.; Duane Loh, N.; Maia, Filipe R.N.C.; Mancuso, Adrian P.; Mühlig, Kerstin; Munke, Anna; Nam, Daewoong; Nettelblad, Carl; Ourmazd, Abbas; Rose, Max; Schwander, Peter; Seibert, Marvin; Sellberg, Jonas A.; Song, Changyong; Spence, John C.H.; Svenda, Martin; Van der Schot, Gijs; Vartanyants, Ivan A.; Williams, Garth J.; Xavier, P. Lourdu

2017-01-01

Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular structure determination without the need for crystallization. In an effort to further develop the technique, we present a dataset of coherent soft X-ray diffraction images of Coliphage PR772 virus, collected at the Atomic Molecular Optics (AMO) beamline with pnCCD detectors in the LAMP instrument at the Linac Coherent Light Source. The diameter of PR772 ranges from 65–70 nm, which is considerably smaller than the previously reported ~600 nm diameter Mimivirus. This reflects continued progress in XFEL-based single-particle imaging towards the single molecular imaging regime. The data set contains significantly more single particle hits than collected in previous experiments, enabling the development of improved statistical analysis, reconstruction algorithms, and quantitative metrics to determine resolution and self-consistency. PMID:28654088

Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source

DOE PAGES

Reddy, Hemanth K. N.; Yoon, Chun Hong; Aquila, Andrew; ...

2017-06-27

Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular structure determination without the need for crystallization. In an effort to further develop the technique, we present a dataset of coherent soft X-ray diffraction images of Coliphage PR772 virus, collected at the Atomic Molecular Optics (AMO) beamline with pnCCD detectors in the LAMP instrument at the Linac Coherent Light Source. The diameter of PR772 ranges from 65–70 nm, which is considerably smaller than the previously reported ~600 nm diameter Mimivirus. This reflects continued progress in XFEL-based single-particle imaging towards the single molecular imaging regime. As a result, themore » data set contains significantly more single particle hits than collected in previous experiments, enabling the development of improved statistical analysis, reconstruction algorithms, and quantitative metrics to determine resolution and self-consistency.« less

Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source.

PubMed

Reddy, Hemanth K N; Yoon, Chun Hong; Aquila, Andrew; Awel, Salah; Ayyer, Kartik; Barty, Anton; Berntsen, Peter; Bielecki, Johan; Bobkov, Sergey; Bucher, Maximilian; Carini, Gabriella A; Carron, Sebastian; Chapman, Henry; Daurer, Benedikt; DeMirci, Hasan; Ekeberg, Tomas; Fromme, Petra; Hajdu, Janos; Hanke, Max Felix; Hart, Philip; Hogue, Brenda G; Hosseinizadeh, Ahmad; Kim, Yoonhee; Kirian, Richard A; Kurta, Ruslan P; Larsson, Daniel S D; Duane Loh, N; Maia, Filipe R N C; Mancuso, Adrian P; Mühlig, Kerstin; Munke, Anna; Nam, Daewoong; Nettelblad, Carl; Ourmazd, Abbas; Rose, Max; Schwander, Peter; Seibert, Marvin; Sellberg, Jonas A; Song, Changyong; Spence, John C H; Svenda, Martin; Van der Schot, Gijs; Vartanyants, Ivan A; Williams, Garth J; Xavier, P Lourdu

2017-06-27

Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular structure determination without the need for crystallization. In an effort to further develop the technique, we present a dataset of coherent soft X-ray diffraction images of Coliphage PR772 virus, collected at the Atomic Molecular Optics (AMO) beamline with pnCCD detectors in the LAMP instrument at the Linac Coherent Light Source. The diameter of PR772 ranges from 65-70 nm, which is considerably smaller than the previously reported ~600 nm diameter Mimivirus. This reflects continued progress in XFEL-based single-particle imaging towards the single molecular imaging regime. The data set contains significantly more single particle hits than collected in previous experiments, enabling the development of improved statistical analysis, reconstruction algorithms, and quantitative metrics to determine resolution and self-consistency.

The defining role of structure (including epitaxy) in the plausibility of homeopathy.

PubMed

Rao, Manju Lata; Roy, Rustum; Bell, Iris R; Hoover, Richard

2007-07-01

The key stumbling block to serious consideration of homeopathy is the presumed "implausibility" of biological activity for homeopathic medicines in which the source material is diluted past Avogadro's number of molecules. Such an argument relies heavily on the assumptions of elementary chemistry (and biochemistry), in which the material composition of a solution, (dilution factors and ligand-receptor interactions), is the essential consideration. In contrast, materials science focuses on the three-dimensional complex network structure of the condensed phase of water itself, rather than the original solute molecules. The nanoheterogenous structure of water can be determined by interactive phenomena such as epitaxy (the transmission of structural information from the surface of one material to another without the transfer of any matter), temperature-pressure processes during succussion, and formation of colloidal nanobubbles containing gaseous inclusions of oxygen, nitrogen, carbon dioxide, and possibly the remedy source material. Preliminary data obtained using Raman and Ultra-Violet-Visible (UV-VIS) spectroscopy illustrate the ability to distinguish two different homeopathic medicines (Nux vomica and Natrum muriaticum) from one another and to differentiate, within a given medicine, the 6c, 12c, and 30c potencies. Materials science concepts and experimental tools offer a new approach to contemporary science, for making significant advances in the basic science studies of homeopathic medicines.

Substance abuse treatment and services by criminal justice and other funding sources.

PubMed

Arfken, Cynthia L; Kubiak, Sheryl Pimlott

2009-01-01

Studies have found funding source, whether public or private, is associated with treatment and services offered in community-based agencies. However, the association of criminal justice funding with community-based treatment and services is unknown. Using a mixed method case study approach with 34 agencies within one state we assessed administrators' perspectives of the most important funding source, treatment and services offered. We found that agencies rely on multiple funding sources and the source rated most important was associated with treatment and services offered in the agency. Those agencies citing a criminal justice entity as the most important funder were more likely to offer specific ancillary services and adopt motivational interviewing than those citing private funds. Although client characteristics or training opportunities may determine these services and practices, the agency's most important funding source may have implications for services offered.

Production Design: Holding It Together.

ERIC Educational Resources Information Center

Connelly, James O.

1994-01-01

Discusses production design for videos. Outlines general considerations (opening, transitions, content areas, and closing) and specific considerations (typography, screen design, music, and sound effects). Offers an example. (SR)

Microscopic Optical Projection Tomography In Vivo

PubMed Central

Meyer, Heiko; Ripoll, Jorge; Tavernarakis, Nektarios

2011-01-01

We describe a versatile optical projection tomography system for rapid three-dimensional imaging of microscopic specimens in vivo. Our tomographic setup eliminates the in xy and z strongly asymmetric resolution, resulting from optical sectioning in conventional confocal microscopy. It allows for robust, high resolution fluorescence as well as absorption imaging of live transparent invertebrate animals such as C. elegans. This system offers considerable advantages over currently available methods when imaging dynamic developmental processes and animal ageing; it permits monitoring of spatio-temporal gene expression and anatomical alterations with single-cell resolution, it utilizes both fluorescence and absorption as a source of contrast, and is easily adaptable for a range of small model organisms. PMID:21559481

Real-World Evidence: What It Is and What It Can Tell Us According to the International Society for Pharmacoepidemiology (ISPE) Comparative Effectiveness Research (CER) Special Interest Group (SIG).

PubMed

Yuan, Hongbo; Ali, M Sanni; Brouwer, Emily S; Girman, Cynthia J; Guo, Jeff J; Lund, Jennifer L; Patorno, Elisabetta; Slaughter, Jonathan L; Wen, Xuerong; Bennett, Dimitri

2018-05-07

On December 8, 2016, the New England Journal of Medicine published a sounding board on Real World Evidence (RWE) 1 by the US Food and Drug Administration (FDA) leadership. While the value of RWE based on nonrandomized observational studies was appreciated, such as for hypothesis generating, safety, and measuring quality in healthcare delivery, the authors expressed concerns on the quality of data sources and the ability of methodologies to control for confounding. In response, we offer a few considerations regarding these concerns. © 2018, The American Society for Clinical Pharmacology and Therapeutics.

Natural and Anthropogenically Perturbed Biogenic Aerosol over Tropical South East Asia

NASA Astrophysics Data System (ADS)

Coe, H.; Robinson, N.; Allan, J. D.; Hewitt, C. N.

2014-12-01

Tropical forested regions are of interest as sources of atmospheric aerosol since they cover very large areas of the tropics and are a source of a large amount of volatile organic compounds which act as precursors for particle formation. Natural forest regions offer the potential to study the background state of the tropics and so potentially gain some insight into the pre-perturbed atmosphere. However, over the last decade in South East Asia, a considerable fraction of the native tropical deciduous forest has been deforested and replanted with palm oil plantations. This changes the range of volatile organic compounds that are emitted and act as sources of secondary organic aerosol. A suite of intensive ground and airborne measurements were made over both tropical forest and oil palm plantations in Sabah, Malaysia as part of the "Oxidant and Particle Photochemical Processes above a South East Asian tropical rainforest (OP3) during 2008. These data will be used together with recent improvements in our understanding of aerosol formation from biogenic compounds to discuss aerosol formation in tropical regions and the influence of human influence through widespread palm oil agriculture.

15 CFR 1160.24 - Antitrust considerations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Partnership Initiative § 1160.24 Antitrust considerations. (a) The Department of Commerce will offer no... Strategic Partnership Initiative is to make the private sector aware of this vehicle and, where requested...

Opportunities for Switzerland to Contribute to the Production of Algal Biofuels: the Hydrothermal Pathway to Bio-Methane.

PubMed

Bagnoud-Velásquez, Mariluz; Refardt, Dominik; Vuille, François; Ludwig, Christian

2015-01-01

Microalgae have a significant potential to be a sustainable source of fuel and thus are of interest in the transition to a sustainable energy system, in particular for resource-dependent countries such as Switzerland. Independence of fossil fuels, considerable reduction of CO(2) emissions, and abandoning nuclear energy may be possible with an integrated system approach including the sourcing of biofuels from different types of biomass. Today, a full carbon-to-fuel conversion is possible, and has been recently demonstrated with an advanced hydrothermal technology. The potential to develop algal biofuels is viewed as high thanks to the possibility they offer to uncouple bioenergy from food production. Nevertheless, technological breakthroughs must take place before commercial production becomes a reality, especially to meet the necessary cost savings and efficiency gains in the algae cultivation structure. In addition, an integrated management of waste resources to promote the nutrient recovery appears today as imperative to further improve the economic viability and the environmental sustainability of algal production. We provide here a review that includes the global technological status of both algae production and their conversion into biofuels in order to understand first the added value of algal energy in general before we focus on the potential of algae to contribute specifically to the Swiss energy system to the horizon 2050. In this respect, the hydrothermal conversion pathway of microalgal biomass into synthetic natural gas (SNG) is emphasized, as research into this technology has received considerable attention in Switzerland during the last decade. In addition, SNG is a particularly relevant fuel in the Swiss context due to the existing gas grid and to the opportunity it offers to cover a wide spectrum of energy applications, in particular cogeneration of heat and electricity or use as a transport fuel in the growing gas car fleet.

Reading and reading instruction for children from low-income and non-English-speaking households.

PubMed

Lesaux, Nonie K

2012-01-01

Although most young children seem to master reading skills in the early grades of elementary school, many struggle with texts as they move through middle school and high school. Why do children who seem to be proficient readers in third grade have trouble comprehending texts in later grades? To answer this question, Nonie Lesaux describes what is known about reading development and instruction, homing in on research conducted with children from low-income and non-English-speaking homes. Using key insights from this research base, she offers two explanations. The first is that reading is a dynamic and multifaceted process that requires continued development if students are to keep pace with the increasing demands of school texts and tasks. The second lies in the role of reading assessment and instruction in U.S. schools. Lesaux draws a distinction between the "skills-based competencies" that readers need to sound out and recognize words and the "knowledge-based competencies" that include the conceptual and vocabulary knowledge necessary to comprehend a text's meaning. Although U.S. schools have made considerable progress in teaching skills-based reading competencies that are the focus of the early grades, most have made much less progress in teaching the knowledge-based competencies students need to support reading comprehension in middle and high school. These knowledge-based competencies are key sources of lasting individual differences in reading outcomes, particularly among children growing up in low-income and non-English-speaking households. Augmenting literacy rates, Lesaux explains, will require considerable shifts in the way reading is assessed and taught in elementary and secondary schools. First, schools must conduct comprehensive reading assessments that discern learners' (potential) sources of reading difficulties--in both skills-based and knowledge-based competencies. Second, educators must implement instructional approaches that offer promise for teaching the conceptual and knowledge-based reading competencies that are critical for academic success, particularly for academically vulnerable populations.

Coercion, incarceration, and chemical castration: an argument from autonomy.

PubMed

Douglas, Thomas; Bonte, Pieter; Focquaert, Farah; Devolder, Katrien; Sterckx, Sigrid

2013-10-01

In several jurisdictions, sex offenders may be offered chemical castration as an alternative to further incarceration. In some, agreement to chemical castration may be made a formal condition of parole or release. In others, refusal to undergo chemical castration can increase the likelihood of further incarceration though no formal link is made between the two. Offering chemical castration as an alternative to further incarceration is often said to be partially coercive, thus rendering the offender's consent invalid. The dominant response to this objection has been to argue that any coercion present in such cases is compatible with valid consent. In this article, we take a different tack, arguing that, even if consent would not be valid, offering chemical castration will often be supported by the very considerations that underpin concerns about consent: considerations of autonomy. This is because offering chemical castration will often increase the offender's autonomy, both at the time the offer is made and in the future.

Open Source and ROI: Open Source Has Made Significant Leaps in Recent Years. What Does It Have to Offer Education?

ERIC Educational Resources Information Center

Guhlin, Miguel

2007-01-01

A switch to free open source software can minimize cost and allow funding to be diverted to equipment and other programs. For instance, the OpenOffice suite is an alternative to expensive basic application programs offered by major vendors. Many such programs on the market offer features seldom used in education but for which educators must pay.…

On recontamination and directional-bias problems in Monte Carlo simulation of PDF turbulence models

NASA Technical Reports Server (NTRS)

Hsu, Andrew T.

1991-01-01

Turbulent combustion can not be simulated adequately by conventional moment closure turbulence models. The difficulty lies in the fact that the reaction rate is in general an exponential function of the temperature, and the higher order correlations in the conventional moment closure models of the chemical source term can not be neglected, making the applications of such models impractical. The probability density function (pdf) method offers an attractive alternative: in a pdf model, the chemical source terms are closed and do not require additional models. A grid dependent Monte Carlo scheme was studied, since it is a logical alternative, wherein the number of computer operations increases only linearly with the increase of number of independent variables, as compared to the exponential increase in a conventional finite difference scheme. A new algorithm was devised that satisfies a restriction in the case of pure diffusion or uniform flow problems. Although for nonuniform flows absolute conservation seems impossible, the present scheme has reduced the error considerably.

Neutron-rich nuclei in cosmic rays and Wolf-Rayet stars

NASA Technical Reports Server (NTRS)

Prantzos, N.; Arnould, M.; Arcoragi, J. P.; Casse, M.

1985-01-01

Wolf-Rayet stars figure prominently in astrophysical research. As a bonus, they seem to offer, in the recent past, an interesting connection between classical astronomy and high energy astrophysics due to their unusual composition and their huge mechanical power. The material flowing from WC stars (carbon-rich WR stars) contains gas which has been processed through core-helium burning, i.e., considerably enriched into 12C,16O, 22Ne, and 25,26Mg. This composition is reminiscent of the cosmic ray source anomalies. Encouraging agreement is obtained with observation in the mass range 12 A 26 assuming acceleration of wind particles at the shock that delineates the WR cavity, and adequate dilution with normal cosmic rays, but silicon poses.

Methods to Improve Reliability of Video Recorded Behavioral Data

PubMed Central

Haidet, Kim Kopenhaver; Tate, Judith; Divirgilio-Thomas, Dana; Kolanowski, Ann; Happ, Mary Beth

2009-01-01

Behavioral observation is a fundamental component of nursing practice and a primary source of clinical research data. The use of video technology in behavioral research offers important advantages to nurse scientists in assessing complex behaviors and relationships between behaviors. The appeal of using this method should be balanced, however, by an informed approach to reliability issues. In this paper, we focus on factors that influence reliability, such as the use of sensitizing sessions to minimize participant reactivity and the importance of training protocols for video coders. In addition, we discuss data quality, the selection and use of observational tools, calculating reliability coefficients, and coding considerations for special populations based on our collective experiences across three different populations and settings. PMID:19434651

Neutron-rich nuclei in cosmic rays and Wolf-Rayet stars

NASA Astrophysics Data System (ADS)

Prantzos, N.; Arcoragi, J. P.; Arnould, M.; Casse, M.

1985-08-01

Wolf-Rayet stars figure prominently in astrophysical research. As a bonus, they seem to offer, in the recent past, an interesting connection between classical astronomy and high energy astrophysics due to their unusual composition and their huge mechanical power. The material flowing from WC stars (carbon-rich WR stars) contains gas which has been processed through core-helium burning, i.e., considerably enriched into 12C,16O, 22Ne, and 25,26Mg. This composition is reminiscent of the cosmic ray source anomalies. Encouraging agreement is obtained with observation in the mass range 12 A 26 assuming acceleration of wind particles at the shock that delineates the WR cavity, and adequate dilution with normal cosmic rays, but silicon poses.

[From record keeping to scientific research: obstacles and opportunities for research with electronic health records].

PubMed

Scholte, R A; Opmeer, B C; Ploem, M C

2017-01-01

As a result of increasing digitisation of medical record keeping, electronic health records (EHRs) are an attractive source for data reuse. However, such record-based research is still suffering from poor quality of data stored in EHRs. Lack of consent for reuse of data also plays an impeding role, especially in retrospective record-based research. That said, increasing cooperation between healthcare institutions and current attention for EHR organisation also offer opportunities for record-based research. Patient data can be recorded in more standardised ways and in increasingly harmonised EHRs. In addition, if healthcare institutions were to establish a generic consent procedure - preferably with national scope - the potential of EHRs for scientific research could be exploited in considerably better ways.

17 CFR 230.251 - Scope of exemption.

Code of Federal Regulations, 2012 CFR

2012-04-01

... consideration must be reasonable at the time made. (c) Integration with other offerings. Offers and sales made... confirmation of sale, unless it has been delivered to that person at an earlier time. (ii) Sales by a dealer...

17 CFR 230.251 - Scope of exemption.

Code of Federal Regulations, 2013 CFR

2013-04-01

... consideration must be reasonable at the time made. (c) Integration with other offerings. Offers and sales made... confirmation of sale, unless it has been delivered to that person at an earlier time. (ii) Sales by a dealer...

17 CFR 230.251 - Scope of exemption.

Code of Federal Regulations, 2014 CFR

2014-04-01

... consideration must be reasonable at the time made. (c) Integration with other offerings. Offers and sales made... confirmation of sale, unless it has been delivered to that person at an earlier time. (ii) Sales by a dealer...

Inferring source attribution from a multiyear multisource data set of Salmonella in Minnesota.

PubMed

Ahlstrom, C; Muellner, P; Spencer, S E F; Hong, S; Saupe, A; Rovira, A; Hedberg, C; Perez, A; Muellner, U; Alvarez, J

2017-12-01

Salmonella enterica is a global health concern because of its widespread association with foodborne illness. Bayesian models have been developed to attribute the burden of human salmonellosis to specific sources with the ultimate objective of prioritizing intervention strategies. Important considerations of source attribution models include the evaluation of the quality of input data, assessment of whether attribution results logically reflect the data trends and identification of patterns within the data that might explain the detailed contribution of different sources to the disease burden. Here, more than 12,000 non-typhoidal Salmonella isolates from human, bovine, porcine, chicken and turkey sources that originated in Minnesota were analysed. A modified Bayesian source attribution model (available in a dedicated R package), accounting for non-sampled sources of infection, attributed 4,672 human cases to sources assessed here. Most (60%) cases were attributed to chicken, although there was a spike in cases attributed to a non-sampled source in the second half of the study period. Molecular epidemiological analysis methods were used to supplement risk modelling, and a visual attribution application was developed to facilitate data exploration and comprehension of the large multiyear data set assessed here. A large amount of within-source diversity and low similarity between sources was observed, and visual exploration of data provided clues into variations driving the attribution modelling results. Results from this pillared approach provided first attribution estimates for Salmonella in Minnesota and offer an understanding of current data gaps as well as key pathogen population features, such as serotype frequency, similarity and diversity across the sources. Results here will be used to inform policy and management strategies ultimately intended to prevent and control Salmonella infection in the state. © 2017 Blackwell Verlag GmbH.

Getting my child to eat the right amount. Mothers' considerations when deciding how much food to offer their child at a meal

USDA-ARS?s Scientific Manuscript database

Feeding young children successfully requires parenting skills,trust that children will eat, and nutrition and child development knowledge to ensure that foods and the amounts offered are developmentally appropriate. Mothers are often responsible for determining how much food is offered to their chil...

An investor perspective on forming and funding your medical device start-up.

PubMed

Mas, Juan-Pablo; Hsueh, Brian

2017-06-01

Novel and transformative medical technologies of all forms have the potential to make a significant positive impact on the lives of patients and on the health care system, and one common pathway for guiding such innovations from concept through commercialization is via the formation of a company. For entrepreneurs looking to build a medical technology company, several common challenges await, including questions around how and where to raise funding. Here, we review key considerations for the formation of medical technology companies as viewed through the lens of an investor. We survey common sources of capital for early-stage companies, including grants, angel investors, and venture capital, and offer insights into how to differentiate among them to select the best partners for your start-up׳s needs. Finally, we discuss the critical components of pitching your ideas to potential investors, and offer guidance on best practices and common mistakes. We hope this primer on fundamental concepts and the various health care funding alternatives will prepare entrepreneurs to achieve their mission to improve patients׳ lives through commercialization of their medical innovations. Copyright © 2017 Elsevier Inc. All rights reserved.

Electric field stimulated growth of Zn whiskers

NASA Astrophysics Data System (ADS)

Niraula, D.; McCulloch, J.; Warrell, G. R.; Irving, R.; Karpov, V. G.; Shvydka, Diana

2016-07-01

We have investigated the impact of strong (˜104 V/cm) electric fields on the development of Zn whiskers. The original samples, with considerable whisker infestation were cut from Zn-coated steel floors and then exposed to electric fields stresses for 10-20 hours at room temperature. We used various electric field sources, from charges accumulated in samples irradiated by: (1) the electron beam of a scanning electron microscope (SEM), (2) the electron beam of a medical linear accelerator, and (3) the ion beam of a linear accelerator; we also used (4) the electric field produced by a Van der Graaf generator. In all cases, the exposed samples exhibited a considerable (tens of percent) increase in whiskers concentration compared to the control sample. The acceleration factor defined as the ratio of the measured whisker growth rate over that in zero field, was estimated to approach several hundred. The statistics of lengths of e-beam induced whiskers was found to follow the log-normal distribution known previously for metal whiskers. The observed accelerated whisker growth is attributed to electrostatic effects. These results offer promise for establishing whisker-related accelerated life testing protocols.

Agricultural biotechnology and smallholder farmers in developing countries.

PubMed

Anthony, Vivienne M; Ferroni, Marco

2012-04-01

Agricultural biotechnology holds much potential to contribute towards crop productivity gains and crop improvement for smallholder farmers in developing countries. Over 14 million smallholder farmers are already benefiting from biotech crops such as cotton and maize in China, India and other Asian, African and Central/South American countries. Molecular breeding can accelerate crop improvement timescales and enable greater use of diversity of gene sources. Little impact has been realized to date with fruits and vegetables because of development timescales for molecular breeding and development and regulatory costs and political considerations facing biotech crops in many countries. Constraints to the development and adoption of technology-based solutions to reduce yield gaps need to be overcome. Full integration with broader commercial considerations such as farmer access to seed distribution systems that facilitate dissemination of improved varieties and functioning markets for produce are critical for the benefits of agricultural biotechnology to be fully realized by smallholders. Public-private partnerships offer opportunities to catalyze new approaches and investment while accelerating integrated research and development and commercial supply chain-based solutions. Copyright © 2011. Published by Elsevier Ltd.

A review of the validity and reliability of alcohol retail sales data for monitoring population levels of alcohol consumption: a Scottish perspective.

PubMed

Robinson, Mark; Thorpe, Rachel; Beeston, Clare; McCartney, Gerry

2013-01-01

To assess the validity and reliability of using alcohol retail sales data to measure and monitor population levels of alcohol consumption. Potential sources of bias that could lead to under- or overestimation of population alcohol consumption based on alcohol retail sales data were identified and, where possible, quantified. This enabled an assessment of the potential impact of each bias on alcohol consumption estimates in Scotland. Overall, considering all the possible sources of overestimation and underestimation, and taking into account the potential for sampling variability to impact on the results, the range of uncertainty of consumption during 2010 was from an overestimate of 0.3 l to an underestimate of 2.4 l of pure alcohol per adult. This excludes the impacts of alcohol stockpiling and alcohol sold through outlets not included in the sampling frame. On balance, there is therefore far greater scope for alcohol retail sales data to be underestimating per adult alcohol consumption in Scotland than there is for overestimation. Alcohol retail sales data offer a robust source of data for monitoring per adult alcohol consumption in Scotland. Consideration of the sources of bias and a comprehensive understanding of data collection methods are essential for using sales data to monitor trends in alcohol consumption.

Design Considerations of a Virtual Laboratory for Advanced X-ray Sources

NASA Astrophysics Data System (ADS)

Luginsland, J. W.; Frese, M. H.; Frese, S. D.; Watrous, J. J.; Heileman, G. L.

2004-11-01

The field of scientific computation has greatly advanced in the last few years, resulting in the ability to perform complex computer simulations that can predict the performance of real-world experiments in a number of fields of study. Among the forces driving this new computational capability is the advent of parallel algorithms, allowing calculations in three-dimensional space with realistic time scales. Electromagnetic radiation sources driven by high-voltage, high-current electron beams offer an area to further push the state-of-the-art in high fidelity, first-principles simulation tools. The physics of these x-ray sources combine kinetic plasma physics (electron beams) with dense fluid-like plasma physics (anode plasmas) and x-ray generation (bremsstrahlung). There are a number of mature techniques and software packages for dealing with the individual aspects of these sources, such as Particle-In-Cell (PIC), Magneto-Hydrodynamics (MHD), and radiation transport codes. The current effort is focused on developing an object-oriented software environment using the Rational© Unified Process and the Unified Modeling Language (UML) to provide a framework where multiple 3D parallel physics packages, such as a PIC code (ICEPIC), a MHD code (MACH), and a x-ray transport code (ITS) can co-exist in a system-of-systems approach to modeling advanced x-ray sources. Initial software design and assessments of the various physics algorithms' fidelity will be presented.

Correlation of invasive EEG and scalp EEG.

PubMed

Ramantani, Georgia; Maillard, Louis; Koessler, Laurent

2016-10-01

Ever since the implementation of invasive EEG recordings in the clinical setting, it has been perceived that a considerable proportion of epileptic discharges present at a cortical level are missed by routine scalp EEG recordings. Several in vitro, in vivo, and simulation studies have been performed in the past decades aiming to clarify the interrelations of cortical sources with their scalp and invasive EEG correlates. The amplitude ratio of cortical potentials to their scalp EEG correlates, the extent of the cortical area involved in the discharge, as well as the localization of the cortical source and its geometry have been each independently linked to the recording of the cortical discharge with scalp electrodes. The need to elucidate these interrelations has been particularly imperative in the field of epilepsy surgery with its rapidly growing EEG-based localization technologies. Simultaneous multiscale EEG recordings with scalp, subdural and/or depth electrodes, applied in presurgical epilepsy workup, offer an excellent opportunity to shed some light to this fundamental issue. Whereas past studies have considered predominantly neocortical sources in the context of temporal lobe epilepsy, current investigations have included deep sources, as in mesial temporal epilepsy, as well as extratemporal sources. Novel computational tools may serve to provide surrogates for the shortcomings of EEG recording methodology and facilitate further developments in modern electrophysiology. Copyright © 2016 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

Employer Health Insurance Offerings and Employee Enrollment Decisions

PubMed Central

Polsky, Daniel; Stein, Rebecca; Nicholson, Sean; Bundorf, M Kate

2005-01-01

Objective To determine how the characteristics of the health benefits offered by employers affect worker insurance coverage decisions. Data Sources The 1996–1997 and the 1998–1999 rounds of the nationally representative Community Tracking Study Household Survey. Study Design We use multinomial logistic regression to analyze the choice between own-employer coverage, alternative source coverage, and no coverage among employees offered health insurance by their employer. The key explanatory variables are the types of health plans offered and the net premium offered. The models include controls for personal, health plan, and job characteristics. Principal Findings When an employer offers only a health maintenance organization married employees are more likely to decline coverage from their employer and take-up another offer (odds ratio (OR)=1.27, p<.001), while singles are more likely to accept the coverage offered by their employer and less likely to be uninsured (OR=0.650, p<.001). Higher net premiums increase the odds of declining the coverage offered by an employer and remaining uninsured for both married (OR=1.023, p<.01) and single (OR=1.035, p<.001) workers. Conclusions The type of health plan coverage an employer offers affects whether its employees take-up insurance, but has a smaller effect on overall coverage rates for workers and their families because of the availability of alternative sources of coverage. Relative to offering only a non-HMO plan, employers offering only an HMO may reduce take-up among those with alternative sources of coverage, but increase take-up among those who would otherwise go uninsured. By modeling the possibility of take-up through the health insurance offers from the employer of the spouse, the decline in coverage rates from higher net premiums is less than previous estimates. PMID:16174133

A microfabricated, low dark current a-Se detector for measurement of microplasma optical emission in the UV for possible use on-site

NASA Astrophysics Data System (ADS)

Abbaszadeh, Shiva; Karim, Karim S.; Karanassios, Vassili

2013-05-01

Traditionally, samples are collected on-site (i.e., in the field) and are shipped to a lab for chemical analysis. An alternative is offered by using portable chemical analysis instruments that can be used on-site (i.e., in the field). Many analytical measurements by optical emission spectrometry require use of light-sources and of spectral lines that are in the Ultra-Violet (UV, ~200 nm - 400 nm wavelength) region of the spectrum. For such measurements, a portable, battery-operated, fiber-optic spectrometer equipped with an un-cooled, linear, solid-state detector may be used. To take full advantage of the advanced measurement capabilities offered by state-of-the-art solid-state detectors, cooling of the detector is required. But cooling and other thermal management hamper portability and use on-site because they add size and weight and they increase electrical power requirements. To address these considerations, an alternative was implemented, as described here. Specifically, a microfabricated solid-state detector for measurement of UV photons will be described. Unlike solid-state detectors developed on crystalline Silicon, this miniaturized and low-cost detector utilizes amorphous Selenium (a-Se) as its photosensitive material. Due to its low dark current, this detector does not require cooling, thus it is better suited for portable use and for chemical measurements on-site. In this paper, a microplasma will be used as a light-source of UV photons for the a-Se detector. For example, spectra acquired using a microplasma as a light-source will be compared with those obtained with a portable, fiber-optic spectrometer equipped with a Si-based 2080-element detector. And, analytical performance obtained by introducing ng-amounts of analytes into the microplasma will be described.

TRENTOOL: A Matlab open source toolbox to analyse information flow in time series data with transfer entropy

PubMed Central

2011-01-01

Background Transfer entropy (TE) is a measure for the detection of directed interactions. Transfer entropy is an information theoretic implementation of Wiener's principle of observational causality. It offers an approach to the detection of neuronal interactions that is free of an explicit model of the interactions. Hence, it offers the power to analyze linear and nonlinear interactions alike. This allows for example the comprehensive analysis of directed interactions in neural networks at various levels of description. Here we present the open-source MATLAB toolbox TRENTOOL that allows the user to handle the considerable complexity of this measure and to validate the obtained results using non-parametrical statistical testing. We demonstrate the use of the toolbox and the performance of the algorithm on simulated data with nonlinear (quadratic) coupling and on local field potentials (LFP) recorded from the retina and the optic tectum of the turtle (Pseudemys scripta elegans) where a neuronal one-way connection is likely present. Results In simulated data TE detected information flow in the simulated direction reliably with false positives not exceeding the rates expected under the null hypothesis. In the LFP data we found directed interactions from the retina to the tectum, despite the complicated signal transformations between these stages. No false positive interactions in the reverse directions were detected. Conclusions TRENTOOL is an implementation of transfer entropy and mutual information analysis that aims to support the user in the application of this information theoretic measure. TRENTOOL is implemented as a MATLAB toolbox and available under an open source license (GPL v3). For the use with neural data TRENTOOL seamlessly integrates with the popular FieldTrip toolbox. PMID:22098775

TRENTOOL: a Matlab open source toolbox to analyse information flow in time series data with transfer entropy.

PubMed

Lindner, Michael; Vicente, Raul; Priesemann, Viola; Wibral, Michael

2011-11-18

Transfer entropy (TE) is a measure for the detection of directed interactions. Transfer entropy is an information theoretic implementation of Wiener's principle of observational causality. It offers an approach to the detection of neuronal interactions that is free of an explicit model of the interactions. Hence, it offers the power to analyze linear and nonlinear interactions alike. This allows for example the comprehensive analysis of directed interactions in neural networks at various levels of description. Here we present the open-source MATLAB toolbox TRENTOOL that allows the user to handle the considerable complexity of this measure and to validate the obtained results using non-parametrical statistical testing. We demonstrate the use of the toolbox and the performance of the algorithm on simulated data with nonlinear (quadratic) coupling and on local field potentials (LFP) recorded from the retina and the optic tectum of the turtle (Pseudemys scripta elegans) where a neuronal one-way connection is likely present. In simulated data TE detected information flow in the simulated direction reliably with false positives not exceeding the rates expected under the null hypothesis. In the LFP data we found directed interactions from the retina to the tectum, despite the complicated signal transformations between these stages. No false positive interactions in the reverse directions were detected. TRENTOOL is an implementation of transfer entropy and mutual information analysis that aims to support the user in the application of this information theoretic measure. TRENTOOL is implemented as a MATLAB toolbox and available under an open source license (GPL v3). For the use with neural data TRENTOOL seamlessly integrates with the popular FieldTrip toolbox.

Historical nectar assessment reveals the fall and rise of floral resources in Britain.

PubMed

Baude, Mathilde; Kunin, William E; Boatman, Nigel D; Conyers, Simon; Davies, Nancy; Gillespie, Mark A K; Morton, R Daniel; Smart, Simon M; Memmott, Jane

2016-02-04

There is considerable concern over declines in insect pollinator communities and potential impacts on the pollination of crops and wildflowers. Among the multiple pressures facing pollinators, decreasing floral resources due to habitat loss and degradation has been suggested as a key contributing factor. However, a lack of quantitative data has hampered testing for historical changes in floral resources. Here we show that overall floral rewards can be estimated at a national scale by combining vegetation surveys and direct nectar measurements. We find evidence for substantial losses in nectar resources in England and Wales between the 1930s and 1970s; however, total nectar provision in Great Britain as a whole had stabilized by 1978, and increased from 1998 to 2007. These findings concur with trends in pollinator diversity, which declined in the mid-twentieth century but stabilized more recently. The diversity of nectar sources declined from 1978 to 1990 and thereafter in some habitats, with four plant species accounting for over 50% of national nectar provision in 2007. Calcareous grassland, broadleaved woodland and neutral grassland are the habitats that produce the greatest amount of nectar per unit area from the most diverse sources, whereas arable land is the poorest with respect to amount of nectar per unit area and diversity of nectar sources. Although agri-environment schemes add resources to arable landscapes, their national contribution is low. Owing to their large area, improved grasslands could add substantially to national nectar provision if they were managed to increase floral resource provision. This national-scale assessment of floral resource provision affords new insights into the links between plant and pollinator declines, and offers considerable opportunities for conservation.

Historical nectar assessment reveals the fall and rise of floral resources in Britain

NASA Astrophysics Data System (ADS)

Baude, Mathilde; Kunin, William E.; Boatman, Nigel D.; Conyers, Simon; Davies, Nancy; Gillespie, Mark A. K.; Morton, R. Daniel; Smart, Simon M.; Memmott, Jane

2016-02-01

There is considerable concern over declines in insect pollinator communities and potential impacts on the pollination of crops and wildflowers. Among the multiple pressures facing pollinators, decreasing floral resources due to habitat loss and degradation has been suggested as a key contributing factor. However, a lack of quantitative data has hampered testing for historical changes in floral resources. Here we show that overall floral rewards can be estimated at a national scale by combining vegetation surveys and direct nectar measurements. We find evidence for substantial losses in nectar resources in England and Wales between the 1930s and 1970s; however, total nectar provision in Great Britain as a whole had stabilized by 1978, and increased from 1998 to 2007. These findings concur with trends in pollinator diversity, which declined in the mid-twentieth century but stabilized more recently. The diversity of nectar sources declined from 1978 to 1990 and thereafter in some habitats, with four plant species accounting for over 50% of national nectar provision in 2007. Calcareous grassland, broadleaved woodland and neutral grassland are the habitats that produce the greatest amount of nectar per unit area from the most diverse sources, whereas arable land is the poorest with respect to amount of nectar per unit area and diversity of nectar sources. Although agri-environment schemes add resources to arable landscapes, their national contribution is low. Owing to their large area, improved grasslands could add substantially to national nectar provision if they were managed to increase floral resource provision. This national-scale assessment of floral resource provision affords new insights into the links between plant and pollinator declines, and offers considerable opportunities for conservation.

Strategic Design for Delivery with Linked Transportation Assets : Trucks and Drones

DOT National Transportation Integrated Search

2018-01-01

Home delivery by drones as an alternative or complement to traditional delivery by trucks is attracting considerable attention from major retailers and services, as well as startups. While drone delivery may offer considerable economic savings, the f...

Study of Integration Considerations for Wireless Emergency Alerts

DTIC Science & Technology

2014-02-01

affect adoption. Section 4 presents a list of overall considerations for integrating a WEA messaging solution into an existing emergency management...in a product may negatively affect another de- sired quality. This section offers considerations for balancing an organization’s priorities con... affect what emergency management agencies can, should, and must do with respect to conducting exercises and issuing alerts. More information about

Teaching about Contracts.

ERIC Educational Resources Information Center

Froman, Michael; Kosnoff, Kathy

1978-01-01

Presents teaching strategies for introducing high school students to contract law. Offers as a case study a contract agreement between pro football players and team owners. Stresses basic elements of contracts (offer, acceptance, consideration, and understanding the bargaining process). Journal available from the American Bar Association, 1155…

Near-Field Magnetic Dipole Moment Analysis

NASA Technical Reports Server (NTRS)

Harris, Patrick K.

2003-01-01

This paper describes the data analysis technique used for magnetic testing at the NASA Goddard Space Flight Center (GSFC). Excellent results have been obtained using this technique to convert a spacecraft s measured magnetic field data into its respective magnetic dipole moment model. The model is most accurate with the earth s geomagnetic field cancelled in a spherical region bounded by the measurement magnetometers with a minimum radius large enough to enclose the magnetic source. Considerably enhanced spacecraft magnetic testing is offered by using this technique in conjunction with a computer-controlled magnetic field measurement system. Such a system, with real-time magnetic field display capabilities, has been incorporated into other existing magnetic measurement facilities and is also used at remote locations where transport to a magnetics test facility is impractical.

Constraining past seawater δ18O and temperature records developed from foraminiferal geochemistry

NASA Astrophysics Data System (ADS)

Quinn, T. M.; Thirumalai, K.; Marino, G.

2016-12-01

Paired measurements of magnesium-to-calcium ratios (Mg/Ca) and the stable oxygen isotopic composition (δ18O) in foraminifera have significantly advanced our knowledge of the climate system by providing information on past temperature and seawater δ18O (δ18Osw, a proxy for salinity and ice volume). However, multiple sources of uncertainty exist in transferring these downcore geochemical data into quantitative paleoclimate reconstructions. Here, we develop a computational toolkit entitled Paleo-Seawater Uncertainty Solver (PSU Solver) that performs bootstrap Monte Carlo simulations to constrain these various sources of uncertainty. PSU Solver calculates temperature and δ18Osw, and their respective confidence intervals using an iterative approach with user-defined errors, calibrations, and sea-level curves. Our probabilistic approach yields reduced uncertainty constraints compared to theoretical considerations and commonly used propagation exercises. We demonstrate the applicability of PSU Solver for published records covering three timescales: the late Holocene, the last deglaciation, and the last glacial period. We show that the influence of salinity on Mg/Ca can considerably alter the structure and amplitude of change in the resulting reconstruction and can impact the interpretation of paleoceanographic time series. We also highlight the sensitivity of the records to various inputs of sea-level curves, transfer functions, and uncertainty constraints. PSU Solver offers an expeditious yet rigorous approach to test the robustness of past climate variability inferred from paired Mg/Ca-δ18O measurements.

The undermining effect of facial attractiveness on brain responses to fairness in the Ultimatum Game: an ERP study

PubMed Central

Ma, Qingguo; Hu, Yue; Jiang, Shushu; Meng, Liang

2015-01-01

To investigate the time course of the neural processing of facial attractiveness and its influence on fairness consideration during social interactions, event-related potentials (ERP) were recorded from 21 male subjects performing a two-person Ultimatum Game (UG). During this bargaining game, the male subjects played responders who decided whether to accept offers from female proposers, whose facial images (grouped as “attractive” and “unattractive”) were presented prior to the offer presentation. The behavioral data demonstrated that the acceptance ratio increased with the fairness level of the offers and, more importantly, the subjects were more likely to accept unfair offers when presented with the attractive-face condition compared with the unattractive-face condition. The reaction times (RTs) for five offers (1:9, 2:8, 3:7, 4:6, and 5:5) in the unattractive-face condition were not significantly different. In contrast, the subjects reacted slower to the attractive proposers' unfair offers and quicker to fair offers. The ERP analysis of the face presentation demonstrated a decreased early negativity (N2) and enhanced late positive potentials (LPPs) elicited by the attractive faces compared with the unattractive faces. In addition, the feedback-related negativity (FRN) in response to an offer presentation was not significantly different for the unfair (1:9 and 2:8) and fair (4:6 and 5:5) offers in the attractive-face condition. However, the unfair offers generated larger FRNs compared with the fair offers in the unattractive-face condition (consistent with prior studies). A similar effect was identified for P300. The present study demonstrated an undermining effect of proposer facial attractiveness on responder consideration of offer fairness during the UG. PMID:25805967

Recommendations for Culturally Sensitive Research Methods

ERIC Educational Resources Information Center

Awad, Germine H.; Patall, Erika A.; Rackley, Kadie R.; Reilly, Erin D.

2016-01-01

As the US continues to diversify, methods for accurately assessing human behavior must evolve. This paper offers multicultural research considerations at several stages of the research process for psychological research and consultation. Implications regarding the comparative research framework are discussed and suggestions are offered on how to…

Improving Vocational Students' Consideration of Source Information When Deciding about Science Controversies

ERIC Educational Resources Information Center

Stadtler, Marc; Scharrer, Lisa; Macedo-Rouet, Monica; Rouet, Jean-François; Bromme, Rainer

2016-01-01

We present an empirical investigation of a classroom training fostering vocational students' consideration of source information when deciding about science-based controversies. The training was specifically aimed at raising students' awareness of the division of cognitive labor and the resulting need to take a source's competence into account…

River Rampage: Navigating Your Off-Site Adventure.

ERIC Educational Resources Information Center

Wheat, Ann; Munoz-Weingarten, Sandy

1996-01-01

The City of Phoenix offers a five-day river-based camping experience to at-risk and disabled teens. Describes how professional river outfitters are contracted to run the trips, staffing considerations, liability and safety considerations, and camper orientation. Evaluation showed that participants received lasting measurable benefits, including…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gonder, Jeff; Wood, Eric; Lammert, Michael

Jeff was invited to brief the EPA Mobile Sources Technical Review Subcommittee on considerations regarding potential energy and environmental considerations for connected and automated vehicles. For more information about the MSTRS see http://www2.epa.gov/caaac/mobile-sources-technical-review-subcommittee-mstrs-caaac.

Self-propelled micromotors based on Au-mesoporous silica nanorods

NASA Astrophysics Data System (ADS)

Wang, Ying-Shuai; Xia, Hong; Lv, Chao; Wang, Lei; Dong, Wen-Fei; Feng, Jing; Sun, Hong-Bo

2015-07-01

Here, a chemical powered micromotor from the assembly of Au-SiO2 nanorods is presented. This new micromotor can be propelled efficiently by hydrogen bubbles generated from a hydrolysis reaction of aqueous NaBH4 and KBH4 and by oxygen bubbles produced by decomposition of H2O2. The monodisperse Au nanoparticles in mesoporous silica particles could catalyze the decomposition of two different kinds of fuels and produce bubbles. High speeds of 80 μm s-1 and recycles of more than 30 times are achieved in both NaBH4 and H2O2 media. Locomotion and rolling forms of movement were found. The locomotion forms can be obtained in a larger proportion by patterning the Au-SiO2 nanorods and a PDMS membrane. These micromotors that use multiple fuel sources to power them offer a broader scope of preparation and show considerable promise for diverse applications of nanomotors in different chemical environments.Here, a chemical powered micromotor from the assembly of Au-SiO2 nanorods is presented. This new micromotor can be propelled efficiently by hydrogen bubbles generated from a hydrolysis reaction of aqueous NaBH4 and KBH4 and by oxygen bubbles produced by decomposition of H2O2. The monodisperse Au nanoparticles in mesoporous silica particles could catalyze the decomposition of two different kinds of fuels and produce bubbles. High speeds of 80 μm s-1 and recycles of more than 30 times are achieved in both NaBH4 and H2O2 media. Locomotion and rolling forms of movement were found. The locomotion forms can be obtained in a larger proportion by patterning the Au-SiO2 nanorods and a PDMS membrane. These micromotors that use multiple fuel sources to power them offer a broader scope of preparation and show considerable promise for diverse applications of nanomotors in different chemical environments. Electronic supplementary information (ESI) available: More electronic microscopy graphs, UV-Vis spectra and N2 adsorption isotherms. See DOI: 10.1039/c5nr02545a

Is This Information Source Commercially Biased? How Contradictions between Web Pages Stimulate the Consideration of Source Information

ERIC Educational Resources Information Center

Kammerer, Yvonne; Kalbfell, Eva; Gerjets, Peter

2016-01-01

In two experiments we systematically examined whether contradictions between two web pages--of which one was commercially biased as stated in an "about us" section--stimulated university students' consideration of source information both during and after reading. In Experiment 1 "about us" information of the web pages was…

Elliptic Cylinder Airborne Sampling and Geostatistical Mass Balance Approach for Quantifying Local Greenhouse Gas Emissions.

PubMed

Tadić, Jovan M; Michalak, Anna M; Iraci, Laura; Ilić, Velibor; Biraud, Sébastien C; Feldman, Daniel R; Bui, Thaopaul; Johnson, Matthew S; Loewenstein, Max; Jeong, Seongeun; Fischer, Marc L; Yates, Emma L; Ryoo, Ju-Mee

2017-09-05

In this study, we explore observational, experimental, methodological, and practical aspects of the flux quantification of greenhouse gases from local point sources by using in situ airborne observations, and suggest a series of conceptual changes to improve flux estimates. We address the major sources of uncertainty reported in previous studies by modifying (1) the shape of the typical flight path, (2) the modeling of covariance and anisotropy, and (3) the type of interpolation tools used. We show that a cylindrical flight profile offers considerable advantages compared to traditional profiles collected as curtains, although this new approach brings with it the need for a more comprehensive subsequent analysis. The proposed flight pattern design does not require prior knowledge of wind direction and allows for the derivation of an ad hoc empirical correction factor to partially alleviate errors resulting from interpolation and measurement inaccuracies. The modified approach is applied to a use-case for quantifying CH 4 emission from an oil field south of San Ardo, CA, and compared to a bottom-up CH 4 emission estimate.

Getting the message: media images and stereotypes and their effect on Asian Americans.

PubMed

Mok, T A

1998-01-01

Mass media sources such as television and movies arguably offer up little in the way of positive Asian/Asian American images or role models. This article contends that the media do not often portray the diversity that is inherent within the Asian American culture and that such a paucity of Asian images may greatly affect perceptions Asian Americans may hold both of their own racial group and of the larger society. This article examines both media images of Asians and Asian Americans and autobiographical information from Asian American literature to illustrate the potentially detrimental effects of being a person of color in a society that emphasizes a monoracial standard of beauty. Information gleaned from first-hand accounts from Asian Americans often points to the media as a potent source of information as to how attractiveness is defined and measured. This article concludes with a discussion of some brief case examples and ethical imperatives for mental health workers in terms of both self-awareness and education as well as considerations for culturally sensitive therapy.

Marine Algicolous Endophytic Fungi - A Promising Drug Resource of the Era.

PubMed

Sarasan, Manomi; Puthumana, Jayesh; Job, Neema; Han, Jeonghoon; Lee, Jae-Seong; Philip, Rosamma

2017-06-28

Endophytic fungi have currently been acknowledged as the most promising source of bioactive compounds for drug discovery, and considerable progress has been made in exploring their diversity, species richness, and bioprospecting. Fungal endophytes from unique environmental settings offer a pool of potentially useful medicinal entities. Owing to the constant stresses imposed on macroalgae by marine environments, it is believed that algae and their associated endophytic symbionts represent a good source of structurally diverse bioactive secondary metabolites. Despite the proven significance of active metabolites of algal endophytes, little have been exploited. This review highlights the latest discoveries in algicolous endophytic research, with particular focus on the bioactive metabolites from algal endophytes. Compounds are classified according to their reported biological activities, like anticancer, antibacterial, antifungal, and antioxidant properties. Present experimental evidence suggests that a majority of the bioactive metabolites were reported from Phaeophyceae followed by Rhodophyceae and Chlorophyceae. An intensive search for newer and more effective bioactive metabolites has generated a treasure trove of publications, and this review partially covers the literature published up to 2016.

Worldwide measurements of radioxenon background near isotope production facilities, a nuclear power plant and at remote sites: the ‘‘EU/JA-II’’ Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saey, P. R.J.; Ringbom, Anders; Bowyer, Ted W.

The Comprehensive Nuclear-Test-Ban Treaty (CTBT) specifies that radioxenon measurements should be performed at 40 or more stations worldwide within the International Monitoring System (IMS). Measuring radioxenon is one of the principle techniques to detect underground nuclear explosions. Specifically, presence and ratios of different radioxenon isotopes allows determining whether a detection event under consideration originated from a nuclear explosion or a civilian source. However, radioxenon monitoring on a global scale is a novel technology and the global civil background must be characterized sufficiently. This paper lays out a study, based on several unique measurement campaigns, of the worldwide concentrations and sourcesmore » of verification relevant xenon isotopes. It complements the experience already gathered with radioxenon measurements within the CTBT IMS programme and focuses on locations in Belgium, Germany, Kuwait, Thailand and South Africa where very little information was available on ambient xenon levels or interesting sites offered opportunities to learn more about emissions from known sources. The findings corroborate the hypothesis that a few major radioxenon sources contribute in great part to the global radioxenon background. Additionally, the existence of independent sources of 131mXe (the daughter of 131I) has been demonstrated, which has some potential to bias the isotopic signature of signals from nuclear explosions.« less

Sources of Information on HIV and Sexual and Reproductive Health for Couples Living with HIV in Rural Southern Malawi

PubMed Central

Gombachika, Belinda Chimphamba; Chirwa, Ellen; Malata, Address; Maluwa, Alfred

2013-01-01

With wider access to antiretroviral therapy, people living with HIV are reconsidering their reproductive decisions: remarrying and having children. The purpose of the paper is to explore sources of information for reproductive decision used by couples living with HIV in patrilineal and matrilineal districts of Malawi. Data were collected from forty couples from July to December 2010. Our results illuminate five specific issues: some of the informants (1) remarry after divorce/death of a spouse, (2) establish new marriage relationship with spouses living with HIV, and (3) have children hence the need for information to base their decisions. There are (4) shared and interactive couple decisions, and (5) informal networks of people living with HIV are the main sources of information. In addition, in matrilineal community, cultural practices about remarriage set up structures that constrained information availability unlike in patrilineal community where information on sexual and reproductive health, HIV, and AIDS was disseminated during remarriage counselling. However, both sources are not able to provide comprehensive information due to complexity and lack of up to date information. Therefore, health workers should, offer people living with HIV comprehensive information that takes into consideration the cultural specificity of groups, and empower already existing and accepted local structures with sexual and reproductive health, HIV, and AIDS knowledge. PMID:23662206

A Review of the Validity and Reliability of Alcohol Retail Sales Data for Monitoring Population Levels of Alcohol Consumption: A Scottish Perspective

PubMed Central

Robinson, Mark; Thorpe, Rachel; Beeston, Clare; McCartney, Gerry

2013-01-01

Aims: To assess the validity and reliability of using alcohol retail sales data to measure and monitor population levels of alcohol consumption. Methods: Potential sources of bias that could lead to under- or overestimation of population alcohol consumption based on alcohol retail sales data were identified and, where possible, quantified. This enabled an assessment of the potential impact of each bias on alcohol consumption estimates in Scotland. Results: Overall, considering all the possible sources of overestimation and underestimation, and taking into account the potential for sampling variability to impact on the results, the range of uncertainty of consumption during 2010 was from an overestimate of 0.3 l to an underestimate of 2.4 l of pure alcohol per adult. This excludes the impacts of alcohol stockpiling and alcohol sold through outlets not included in the sampling frame. On balance, there is therefore far greater scope for alcohol retail sales data to be underestimating per adult alcohol consumption in Scotland than there is for overestimation. Conclusion: Alcohol retail sales data offer a robust source of data for monitoring per adult alcohol consumption in Scotland. Consideration of the sources of bias and a comprehensive understanding of data collection methods are essential for using sales data to monitor trends in alcohol consumption. PMID:22926649

Stem cells from foetal adnexa and fluid in domestic animals: an update on their features and clinical application.

PubMed

Iacono, E; Rossi, B; Merlo, B

2015-06-01

Over the past decade, stem cell research has emerged as an area of major interest for its potential in regenerative medicine applications. This is in constant need of new cell sources to conceive regenerative medicine approaches for diseases that are still without therapy. Scientists drew the attention towards alternative sources such as foetal adnexa and fluid, as these sources possess many advantages: first of all, cells can be extracted from discarded foetal material and it is non-invasive and inexpensive for the patient; secondly, abundant stem cells can be obtained; and finally, these stem cell sources are free from ethical considerations. Cells derived from foetal adnexa and fluid preserve some of the characteristics of the primitive embryonic layers from which they originate. Many studies have demonstrated the differentiation potential in vitro and in vivo towards mesenchymal and non-mesenchymal cell types; in addition, the immune-modulatory properties make these cells a good candidate for allo- and xenotransplantation. Naturally occurring diseases in domestic animals can be more ideal as disease model of human genetic and acquired diseases and could help to define the potential therapeutic use efficiency and safety of stem cells therapies. This review offers an update on the state of the art of characterization of domestic animals' MSCs derived from foetal adnexa and fluid and on the latest findings in pre-clinical or clinical setting of the stem cell populations isolated from these sources. © 2015 Blackwell Verlag GmbH.

Policy, Systems, and Environmental Change in the Mississippi Delta: Considerations for Evaluation Design

ERIC Educational Resources Information Center

Kegler, Michelle C.; Honeycutt, Sally; Davis, Melvin; Dauria, Emily; Berg, Carla; Dove, Cassandra; Gamble, Abigail; Hawkins, Jackie

2015-01-01

Community-level policy, systems, and environmental (PSE) change strategies may offer an economical and sustainable approach to chronic disease prevention. The rapidly growing number of untested but promising PSE strategies currently underway offers an exciting opportunity to establish practice-based evidence for this approach. This article…

75 FR 27602 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-17

... rules governing offers and sales of securities made outside the United States without registration under... clarification of the extent to which Section 5 of the Securities Act applies to offers and sales of securities... collection techniques or other forms of information technology. Consideration will be given to comments and...

Educational Fund Raising: Principles and Practice. American Council on Education Series on Higher Education.

ERIC Educational Resources Information Center

Worth, Michael J., Ed.

This volume offers 36 papers on higher education fundraising. Major topics treated are the development function, foundations of fund raising, annual giving, major gifts, campaigns, corporate and foundation support, special constituencies, managing development programs, special considerations for institutions, and special considerations for the…

Mesoamerica Writing at the Crossroads: The Late Formative.

ERIC Educational Resources Information Center

Stross, Brian

1990-01-01

Offers an overview of Later Formative period writing in Mesoamerica, and discusses recent findings. Asserts that analysis of the iconographic context of the script reveals considerable interdependence between text and context and provides a glimpse of the importance of cosmological considerations in the display of power. Discusses the importance…

Megasite Management Tool (mmt): a Decision Support System Built Using Mapwindow Activex Control

NASA Astrophysics Data System (ADS)

Pulsani, B. R.

2017-11-01

Megasite Management Tool (MMT) is planning and evaluation software for contaminated sites. Using different statistical modules, MMT produces maps which help decision makers in rehabilitating contaminated sites. The input data used by MMT is of geographic nature and exists as shapefile and raster format. As MMT is built using simple windows forms application, the objective of the study was to find a way to visualize geographic data and to allow the user to edit its attribute information. Therefore, the application requirement was to find GIS libraries which offer capabilities such as (1) map viewer with navigation tools (2) library to read/write geographic data and (3) software which allows free distribution of the developed components. A research on these requirements led to the discovery of MapWindow ActiveX components which not only offered these capabilities but also provided free and open source licensing options for redistribution. Although considerable amount of reports and publications exist on MMT, the major contribution provided by MapWindow libraries have been under played. The current study emphasises upon the contribution and advantages MapWindow ActiveX provides for incorporating GIS functionality to an already existing application. Similar components for other languages have also been reviewed.

Heterogeniety and Heterarchy: How far can network analyses in Earth and space sciences?

NASA Astrophysics Data System (ADS)

Prabhu, A.; Fox, P. A.; Eleish, A.; Li, C.; Pan, F.; Zhong, H.

2017-12-01

The vast majority of explorations of Earth systems are limited in their ability to effectively explore the most important (often most difficult) problems because they are forced to interconnect at the data-element, or syntactic, level rather than at a higher scientific, or conceptual/ semantic, level. Recent successes in the application of complex network theory and algorithms to minerology, fossils and proteins over billions of years of Earth's history, raise expectations that more general graph-based approaches offer the opportunity for new discoveries = needles instead of haystacks. In the past 10 years in the natural sciences there has substantial progress in providing both specialists and non-specialists the ability to describe in machine readable form, geophysical quantities and relations among them in meaningful and natural ways, effectively breaking the prior syntax barrier. The corresponding open-world semantics and reasoning provide higher-level interconnections. That is, semantics provided around the data structures, using open-source tools, allow for discovery at the knowledge level. This presentation will cover the fundamentals of data-rich network analyses for geosciences, provide illustrative examples in mineral evolution and offer future paths for consideration.

Incorporating equity considerations in transport infrastructure evaluation: Current practice and a proposed methodology.

PubMed

Thomopoulos, N; Grant-Muller, S; Tight, M R

2009-11-01

Interest has re-emerged on the issue of how to incorporate equity considerations in the appraisal of transport projects and large road infrastructure projects in particular. This paper offers a way forward in addressing some of the theoretical and practical concerns that have presented difficulties to date in incorporating equity concerns in the appraisal of such projects. Initially an overview of current practice within transport regarding the appraisal of equity considerations in Europe is offered based on an extensive literature review. Acknowledging the value of a framework approach, research towards introducing a theoretical framework is then presented. The proposed framework is based on the well established MCA Analytic Hierarchy Process and is also contrasted with the use of a CBA based approach. The framework outlined here offers an additional support tool to decision makers who will be able to differentiate choices based on their views on specific equity principles and equity types. It also holds the potential to become a valuable tool for evaluators as a result of the option to assess predefined equity perspectives of decision makers against both the project objectives and the estimated project impacts. This framework may also be of further value to evaluators outside transport.

MOMENTS OF UNCERTAINTY: ETHICAL CONSIDERATIONS AND EMERGING CONTAMINANTS

PubMed Central

Cordner, Alissa; Brown, Phil

2013-01-01

Science on emerging environmental health threats involves numerous ethical concerns related to scientific uncertainty about conducting, interpreting, communicating, and acting upon research findings, but the connections between ethical decision making and scientific uncertainty are under-studied in sociology. Under conditions of scientific uncertainty, researcher conduct is not fully prescribed by formal ethical codes of conduct, increasing the importance of ethical reflection by researchers, conflicts over research conduct, and reliance on informal ethical standards. This paper draws on in-depth interviews with scientists, regulators, activists, industry representatives, and fire safety experts to explore ethical considerations of moments of uncertainty using a case study of flame retardants, chemicals widely used in consumer products with potential negative health and environmental impacts. We focus on the uncertainty that arises in measuring people’s exposure to these chemicals through testing of their personal environments or bodies. We identify four sources of ethical concerns relevant to scientific uncertainty: 1) choosing research questions or methods, 2) interpreting scientific results, 3) communicating results to multiple publics, and 4) applying results for policy-making. This research offers lessons about professional conduct under conditions of uncertainty, ethical research practice, democratization of scientific knowledge, and science’s impact on policy. PMID:24249964

Optimization of the production of thermostable endo-beta-1,4 mannanases from a newly isolated Aspergillus niger gr and Aspergillus flavus gr.

PubMed

Kote, Naganagouda V; Patil, Aravind Goud G; Mulimani, V H

2009-02-01

The aim of this work was to establish optimal conditions for the maximum production of endo-beta-1,4 mannanases using cheaper sources. Eight thermotolerant fungal strains were isolated from garden soil and compost samples collected in and around the Gulbarga University campus, India. Two strains were selected based on their ability to produce considerable endo-beta-1,4 mannanases activity while growing in liquid medium at 37 degrees C with locust bean gum (LBG) as the only carbon source. They were identified as Aspergillus niger gr and Aspergillus flavus gr. The experiment to evaluate the effect of different carbon sources, nitrogen sources, temperatures and initial pH of the medium on maximal enzyme production was studied. Enzyme productivity was influenced by the type of polysaccharide used as the carbon source. Copra meal defatted with n-hexane showed to be a better substrate than LBG and guar gum for endo-beta-1,4 mannanases production by A. niger gr (40.011 U/ml), but for A. flavus gr (33.532 U/ml), the difference was not significant. Endo-beta-1,4 mannanases produced from A. niger gr and A. flavus gr have high optimum temperature (65 and 60 degrees C) and good thermostability in the absence of any stabilizers (maintaining 50% of residual activity for 8 and 6 h, respectively, at 60 degrees C) and are stable over in a wide pH range. These new strains offer an attractive alternative source of enzymes for the food and feed processing industries.

48 CFR 13.104 - Promoting competition.

Code of Federal Regulations, 2010 CFR

2010-10-01

... cost of the purchase. (a) The contracting officer must not— (1) Solicit quotations based on personal... practicable competition ordinarily can be obtained by soliciting quotations or offers from sources within the... the maximum extent practicable. Whenever practicable, request quotations or offers from two sources...

Generation of optimal artificial neural networks using a pattern search algorithm: application to approximation of chemical systems.

PubMed

Ihme, Matthias; Marsden, Alison L; Pitsch, Heinz

2008-02-01

A pattern search optimization method is applied to the generation of optimal artificial neural networks (ANNs). Optimization is performed using a mixed variable extension to the generalized pattern search method. This method offers the advantage that categorical variables, such as neural transfer functions and nodal connectivities, can be used as parameters in optimization. When used together with a surrogate, the resulting algorithm is highly efficient for expensive objective functions. Results demonstrate the effectiveness of this method in optimizing an ANN for the number of neurons, the type of transfer function, and the connectivity among neurons. The optimization method is applied to a chemistry approximation of practical relevance. In this application, temperature and a chemical source term are approximated as functions of two independent parameters using optimal ANNs. Comparison of the performance of optimal ANNs with conventional tabulation methods demonstrates equivalent accuracy by considerable savings in memory storage. The architecture of the optimal ANN for the approximation of the chemical source term consists of a fully connected feedforward network having four nonlinear hidden layers and 117 synaptic weights. An equivalent representation of the chemical source term using tabulation techniques would require a 500 x 500 grid point discretization of the parameter space.

Phytochemica: a platform to explore phytochemicals of medicinal plants

PubMed Central

Pathania, Shivalika; Ramakrishnan, Sai Mukund; Bagler, Ganesh

2015-01-01

Plant-derived molecules (PDMs) are known to be a rich source of diverse scaffolds that could serve as the basis for rational drug design. Structured compilation of phytochemicals from traditional medicinal plants can facilitate prospection for novel PDMs and their analogs as therapeutic agents. Atropa belladonna, Catharanthus roseus, Heliotropium indicum, Picrorhiza kurroa and Podophyllum hexandrum are important Himalayan medicinal plants, reported to have immense therapeutic properties against various diseases. We present Phytochemica, a structured compilation of 963 PDMs from these plants, inclusive of their plant part source, chemical classification, IUPAC names, SMILES notations, physicochemical properties and 3-dimensional structures with associated references. Phytochemica is an exhaustive resource of natural molecules facilitating prospection for therapeutic molecules from medicinally important plants. It also offers refined search option to explore the neighbourhood of chemical space against ZINC database to identify analogs of natural molecules at user-defined cut-off. Availability of phytochemical structured dataset may enable their direct use in in silico drug discovery which will hasten the process of lead identification from natural products under proposed hypothesis, and may overcome urgent need for phytomedicines. Compilation and accessibility of indigenous phytochemicals and their derivatives can be a source of considerable advantage to research institutes as well as industries. Database URL: home.iitj.ac.in/∼bagler/webservers/Phytochemica PMID:26255307

Sensitivity Analysis of the Off-Normal Conditions of the SPIDER Accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Veltri, P.; Agostinetti, P.; Antoni, V.

2011-09-26

In the context of the development of the 1 MV neutral beam injector for the ITER tokamak, the study on beam formation and acceleration has considerable importance. This effort includes the ion source and accelerator SPIDER (Source for Production of Ions of Deuterium Extracted from an Rf plasma) ion source, planned to be built in Padova, and designed to extract and accelerate a 355 A/m{sup 2} current of H{sup -}(or 285 A/m{sup 2} D{sup -}) up to 100 kV. Exhaustive simulations were already carried out during the accelerator optimization leading to the present design. However, as it is expected thatmore » the accelerator shall operate also in case of pre-programmed or undesired off-normal conditions, the investigation of a large set of off-normal scenarios is necessary. These analyses will also be useful for the evaluation of the real performances of the machine, and should help in interpreting experimental results, or in identifying dangerous operating conditions.The present contribution offers an overview of the results obtained during the investigation of these off-normal conditions, by means of different modeling tools and codes. The results, showed a good flexibility of the device in different operating conditions. Where the consequences of the abnormalities appeared to be problematic further analysis were addressed.« less

Poly- Versus Mono-Energetic Dual-Spectrum Non-Intrusive Inspection of Cargo Containers

NASA Astrophysics Data System (ADS)

Martz, Harry E.; Glenn, Steven M.; Smith, Jerel A.; Divin, Charles J.; Azevedo, Stephen G.

2017-07-01

In this paper, based on an invited talk at SORMA (May 2016), we present an overview of x-ray sources, detectors and system configurations for non-intrusive inspection (NII) of cargo containers. Our emphasis is on dual-energy x-ray NII for detecting high-atomic-number (Z ≥ 72) materials such as tungsten shielding and special nuclear materials (SNM). Standard single-energy (MeV and above) x-rays needed to penetrate and image cargo provide little SNM contrast, whereas dual-energy x-ray NII is demonstrated as a way to improve the selectivity of materials with Z<;72 vs. those with Z ≥ 72. For two possible dual-energy x-ray source technologies - polyenergetic dual-energy (PDE) and quasi-monoenergetic x-ray sources (QMXS) - we investigate their trade-offs and future prospects using experimental and simulated results. The reduced scatter and larger separation of low- and high-energy photons provided by QMXS offers improved high-Z material contrast, but practical considerations such as flux and pulse rate need to be solved before making a deployable system. Straight-ray simulations show factor of four increases in contrast for QMXS over PDE scans of tin (Z=50) and iron (Z=26) relative to a uranium plate (Z=92) behind 20 cm of iron simulated cargo.

HPTLC in Herbal Drug Quantification

NASA Astrophysics Data System (ADS)

Shinde, Devanand B.; Chavan, Machindra J.; Wakte, Pravin S.

For the past few decades, compounds from natural sources have been gaining importance because of the vast chemical diversity they offer. This has led to phenomenal increase in the demand for herbal medicines in the last two decades and need has been felt for ensuring the quality, safety, and efficacy of herbal drugs. Phytochemical evaluation is one of the tools for the quality assessment, which include preliminary phytochemical screening, chemoprofiling, and marker compound analysis using modern analytical techniques. High-performance thin-layer chromatography (HPTLC) has been emerged as an important tool for the qualitative, semiquantitative, and quantitative phytochemical analysis of the herbal drugs and formulations. This includes developing TLC fingerprinting profiles and estimation of biomarkers. This review has an attempt to focus on the theoretical considerations of HPTLC and some examples of herbal drugs and formulations analyzed by HPTLC.

Implications of protein- and Peptide-based nanoparticles as potential vehicles for anticancer drugs.

PubMed

Elzoghby, Ahmed O; Elgohary, Mayada M; Kamel, Nayra M

2015-01-01

Protein-based nanocarriers have gained considerable attention as colloidal carrier systems for the delivery of anticancer drugs. Protein nanocarriers possess various advantages including their low cytotoxicity, abundant renewable sources, high drug-binding capacity, and significant uptake into the targeted tumor cells. Moreover, the unique protein structure offers the possibility of site-specific drug conjugation and tumor targeting using various ligands modifying the surface of protein nanocarriers. In this chapter, we highlight the most important applications of protein nanoparticles (NPs) for the delivery of anticancer drugs. We examine the various techniques that have been utilized for the preparation of anticancer drug-loaded protein NPs. Finally, the current chapter also reviews the major outcomes of the in vitro and in vivo investigations of surface-modified tumor-targeted protein NPs. © 2015 Elsevier Inc. All rights reserved.

Investigation on the special Smith-Purcell radiation from a nano-scale rectangular metallic grating

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Weiwei; Liu, Weihao, E-mail: liuwhao@ustc.edu.cn; Jia, Qika

The special Smith-Purcell radiation (S-SPR), which is from the radiating eigen modes of a grating, has remarkable higher intensity than the ordinary Smith-Purcell radiation. Yet in previous studies, the gratings were treated as perfect conductor without considering the surface plasmon polaritons (SPPs) which are of significance for the nano-scale gratings especially in the optical region. In present paper, the rigorous theoretical investigations on the S-SPR from a nano-grating with SPPs taken into consideration are carried out. The dispersion relations and radiation characteristics are obtained, and the results are verified by simulations. According to the analyses, the tunable light radiation canmore » be achieved by the S-SPR from a nano-grating, which offers a new prospect for developing the nano-scale light sources.« less

Evaluating the quality of Internet information for femoroacetabular impingement.

PubMed

Lee, Simon; Shin, Jason J; Haro, Marc S; Song, Sang H; Nho, Shane J

2014-10-01

The Internet has become a ubiquitous source of medical information for both the patient and the physician. However, the quality of this information is highly variable. We evaluated the quality of Internet information available for femoroacetabular impingement (FAI). Four popular search engines were used to collect 100 Web sites containing information on FAI. Web sites were evaluated based on authorship, various content criteria, and the presence of Health On the Net Code of Conduct (HONcode) certification. By use of a novel evaluation system for quality, Web sites were also classified as excellent, high, moderate, poor, or inadequate and were subsequently analyzed. Web sites were evaluated as a group, followed by authorship type, by HONcode certification, and by quality level. Of the Web sites, 73 offered the ability to contact the author, 91 offered a considerable explanation of FAI, 54 provided surgical treatment options, 58 offered nonsurgical treatment options, 27 discussed possible complications, 11 discussed eligibility criteria, 31 discussed rehabilitation, 67 discussed a differential diagnosis, and 48 included peer-reviewed citations. We categorized 40 Web sites as academic, 33 as private, 9 as industry, 9 as public education, and 9 as blogs. Our novel quality evaluation system classified 16 Web sites as excellent, 18 as high, 17 as moderate, 18 as poor, and 31 as inadequate. Only 8% of all evaluated Web sites contained HONcode certification. We found that the quality of information available on the Internet about FAI was dramatically variable. A significantly large proportion of Web sites were from academic sources, but this did not necessarily indicate higher quality. Sites with HONcode certification showed as much variability in quality as noncertified sites. This study increases clinician competence in the available Internet information about FAI and helps them to confidently guide patients to formulate appropriate medical decisions based on high-quality information. Copyright © 2014 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

Dynamic Radioisotope Power System Development for Space Explorations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qualls, A L

Dynamic power conversion offers the potential to produce radioisotope power systems (RPS) that generate higher power outputs and utilize the Pu-238 radioisotope more efficiently than Radioisotope Thermoelectric Generators (RTG). Additionally, dynamic systems also offer the potential of producing generators with significantly reduced power degradation over the course of deep space missions so that more power will be available at the end of the mission when it is needed for both powering the science and transmitting the results. The development of dynamic generators involves addressing technical issues not typically associated with traditional thermoelectric generators. Developing long-life, robust and reliable dynamic conversionmore » technology is challenging yet essential to building a suitable generator. Considerations include working within existing handling infrastructure where possible so that development costs can be kept low and integrating dynamic generators into spacecraft, which may be more complex than integration of static systems. Methods of interfacing to and controlling a dynamic generator must be considered and new potential failure modes must be taken into account. This paper will address some of the key issues of dynamic RPS design, development and adaption.Dynamic power conversion offers the potential to produce Radioisotope Power Systems (RPS) that generate higher power outputs and utilize the available heat source plutonium fuel more efficiently than Radioisotope Thermoelectric Generators. Additionally, dynamic systems offer the potential of producing generators with significantly reduced power degradation over the course of deep space missions so that more power would be available at the end of the mission, when it is needed most for both powering science instruments and transmitting the resulting data. The development of dynamic generators involves addressing technical issues not typically associated with traditional thermoelectric generators. Developing long-life, robust, and reliable dynamic conversion technology is challenging yet essential to building a suitable flight-ready generator. Considerations include working within existing hardware-handling infrastructure, where possible, so that development costs can be kept low, and integrating dynamic generators into spacecraft, which may be more complex than integration of static thermoelectric systems. Methods of interfacing to and controlling a dynamic generator must also be considered, and new potential failure modes must be taken into account. This paper will address some of the key issues of dynamic RPS design, development, and adaption.« less

School Provisions for Gifted, Talented and Able Students: A Response to Freeman

ERIC Educational Resources Information Center

Vidergor, Hava

2012-01-01

In this response to Joan Freeman's "A Quality of Giftedness," Have Vidergor states that provisions for gifted, talented, and excellent students should be offered by regular schools, taking into consideration levels of giftedness, offering a variety of interdisciplinary elective courses and subjects to about 20% of the school population,…

Evaluating the Buy or Rent Housing Decision.

ERIC Educational Resources Information Center

Davis, Joseph M.

This booklet offers guidelines by which a person can make an informed decision about whether buying or renting a house is the best individual alternative. Advantages and disadvantages of both buying and renting are listed. Cost considerations are discussed and compared along with such considerations as selection of the time to buy and estimation…

10 CFR 51.104 - NRC proceeding using public hearings; consideration of environmental impact statement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... environmental impact statement. 51.104 Section 51.104 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED....104 NRC proceeding using public hearings; consideration of environmental impact statement. (a)(1) In... scope of NEPA and this subpart are in issue, the NRC staff may not offer the final environmental impact...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kandt, Alicen J

This presentation for the 2017 Energy Exchange in Tampa, Florida, offers information about advanced auditing technologies and techniques including alternative auditing approaches and considerations and caveats.

Performance Criteria of Nuclear Space Propulsion Systems

NASA Astrophysics Data System (ADS)

Shepherd, L. R.

Future exploration of the solar system on a major scale will require propulsion systems capable of performance far greater than is achievable with the present generation of rocket engines using chemical propellants. Viable missions going deeper into interstellar space will be even more demanding. Propulsion systems based on nuclear energy sources, fission or (eventually) fusion offer the best prospect for meeting the requirements. The most obvious gain coming from the application of nuclear reactions is the possibility, at least in principle, of obtaining specific impulses a thousandfold greater than can be achieved in chemically energised rockets. However, practical considerations preclude the possibility of exploiting the full potential of nuclear energy sources in any engines conceivable in terms of presently known technology. Achievable propulsive power is a particularly limiting factor, since this determines the acceleration that may be obtained. Conventional chemical rocket engines have specific propulsive powers (power per unit engine mass) in the order of gigawatts per tonne. One cannot envisage the possibility of approaching such a level of performance by orders of magnitude in presently conceivable nuclear propulsive systems. The time taken, under power, to reach a given terminal velocity is proportional to the square of the engine's exhaust velocity and the inverse of its specific power. An assessment of various nuclear propulsion concepts suggests that, even with the most optimistic assumptions, it could take many hundreds of years to attain the velocities necessary to reach the nearest stars. Exploration within a range of the order of a thousand AU, however, would appear to offer viable prospects, even with the low levels of specific power of presently conceivable nuclear engines.

Employer health insurance offerings and employee enrollment decisions.

PubMed

Polsky, Daniel; Stein, Rebecca; Nicholson, Sean; Bundorf, M Kate

2005-10-01

To determine how the characteristics of the health benefits offered by employers affect worker insurance coverage decisions. The 1996-1997 and the 1998-1999 rounds of the nationally representative Community Tracking Study Household Survey. We use multinomial logistic regression to analyze the choice between own-employer coverage, alternative source coverage, and no coverage among employees offered health insurance by their employer. The key explanatory variables are the types of health plans offered and the net premium offered. The models include controls for personal, health plan, and job characteristics. When an employer offers only a health maintenance organization married employees are more likely to decline coverage from their employer and take-up another offer (odds ratio (OR)=1.27, p<.001), while singles are more likely to accept the coverage offered by their employer and less likely to be uninsured (OR=0.650, p<.001). Higher net premiums increase the odds of declining the coverage offered by an employer and remaining uninsured for both married (OR=1.023, p<.01) and single (OR=1.035, p<.001) workers. The type of health plan coverage an employer offers affects whether its employees take-up insurance, but has a smaller effect on overall coverage rates for workers and their families because of the availability of alternative sources of coverage. Relative to offering only a non-HMO plan, employers offering only an HMO may reduce take-up among those with alternative sources of coverage, but increase take-up among those who would otherwise go uninsured. By modeling the possibility of take-up through the health insurance offers from the employer of the spouse, the decline in coverage rates from higher net premiums is less than previous estimates.

Geothermal Energy.

ERIC Educational Resources Information Center

Eaton, William W.

Described are the origin and nature of geothermal energy. Included is the history of its development as an energy source, technological considerations affecting its development as an energy source, its environmental effects, economic considerations, and future prospects of development in this field. Basic system diagrams of the operation of a…

Innovation versus complexity: what is too much of a good thing?

PubMed

Gottfredson, Mark; Aspinall, Keith

2005-11-01

What's the number of product or service offerings that would optimize both your revenues and your profits? For most firms, it's considerably lower than the number they offer today. The fact is, companies have strong incentives to be overly innovative in new product development. But continual launches of new products and line extensions add complexity throughout a company's operations, and as the costs of managing that complexity multiply, margins shrink. To maximize profit potential, a company needs to identify its innovation fulcrum, the point at which an additional offering destroys more value than it creates. The usual antidotes to complexity miss their mark because they treat the problem on the factory floor rather than at its source: in the product line. Mark Gottfredson and Keith Aspinall of Bain & Company present an approach that goes beyond the typical Six Sigma or lean-operations program to root out complexity hidden in the value chain. The first step is to ask, What would our company look like if it made and sold only a single product or service? In other words, you identify your company's equivalent of Henry Ford's one-size-fits-all Model T-for Starbucks, it might be a medium-size cup of coffee; for a bank, a simple checking account-and then determine the cost of producing that baseline offering. Next, you add variety back into the business system, product by product, and carefully forecast the resulting impact on sales as well as the cost implications across the value chain. When the analysis shows the costs beginning to overwhelm the added revenues, you've found your innovation fulcrum. By deconstructing their companies to a zero-complexity baseline, managers can break through organizational resistance and deeply entrenched ways of thinking to find the right balance between innovation and complexity.

Framing the Socialisation Process of the DBA Candidate: What Can Universities Offer and What Should Candidates Bring?

ERIC Educational Resources Information Center

Pervan, Simon; Blackman, Deborah; Sloan, Terry; Wallace, Michelle; Vocino, Andrea; Byrne, Cathy

2016-01-01

In Australia, the Doctorate of Business Administration (DBA) remains a popular program but considerable anguish persists within the university sector over just what it is offering students. In this article, we use the process of postgraduate socialisation to understand how candidates, supervisors and administrators navigate pathways to successful…

Assistive Technology in Rehabilitation: Improving Impact through Policy

ERIC Educational Resources Information Center

Lewis, Allen N.; Cooper, Rory A.; Seelman, Kate D.; Cooper, Rosemarie; Schein, Richard M.

2012-01-01

This paper addresses the topic of assistive technology (AT) to offer a direction for its future role within the rehabilitation profession. A brief overview of the five AT legislative acts to date is provided. Next, future considerations for AT are offered in the context of what we know within the U.S. and global communities followed by the…

Design considerations for community mental health management information systems.

PubMed

Lowe, B H; Sugarman, B

1978-01-01

Many community mental health centers are presently faced with the necessity of implementing a management information system. This article offers guidelines for centers dealing with this situation. Whether a center chooses to adapt an existing system or develop one of its own, careful planning prior to the implementation of the system can help ensure that it will meet the needs of the center and operate successfully. The guidelines are organized into the categories of data considerations, people considerations, and system considerations. The first two categories are of general interest, whereas the last category is more technical in nature.

When Sexual and Religious Orientation Collide: Considerations in Working with Conflicted Same-Sex Attracted Male Clients

ERIC Educational Resources Information Center

Haldeman, Douglas C.

2004-01-01

The debate among scholars and gay activists and religious/political activists about the appropriateness and efficacy of conversion therapy has left out a number of individuals for whom neither gay-affirmative nor conversion therapy may be indicated. The present discussion, through the use of case material, offers considerations for the…

21 CFR 558.3 - Definitions and general considerations applicable to this part.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Definitions and general considerations applicable to this part. 558.3 Section 558.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH...” (added on top of usual ration) on or offered “free-choice” (e.g., supplement) in conjunction with other...

Beyond bankable dollars: establishing a business case for improving health care.

PubMed

Bailit, Michael; Dyer, Mary Beth

2004-09-01

To address widespread deficiencies in the quality of health care, the authors argue that health care organizations need to be able to make a "business case" for improving quality--a compelling rationale for financial investment in quality improvement programs. The authors' framework for such a business case is organized around three broad areas: direct financial considerations, strategic considerations, and internal organizational considerations. Within these categories, they offer a total of 10 specific business case arguments, with examples, for investing in quality improvement.

Interstitial devices for treating deep seated tumors

NASA Astrophysics Data System (ADS)

Lafon, Cyril; Cathignol, Dominique; Prat, Frédéric; Melodelima, David; Salomir, Rares; Theillère, Yves; Chapelon, Jean-Yves

2006-05-01

Techniques using intracavitary or interstitial applicators have been proposed because extracorporeal HIFU techniques are not always suitable for deep-seated tumors. Bones or gaseous pockets may indeed be located in the intervening tissue. The objective is to bring the ultrasound source as close as possible to the target through natural routes in order to minimize the effects of attenuation and phase aberration along the ultrasound pathway. Under these circumstances, it becomes possible to use higher frequency, thus increasing the ultrasonic absorption coefficient and resulting in more efficient heating of the treatment region. In contrast to extra-corporeal applicators, the design of interstitial probes imposes additional constraints relative to size and ergonomy. The goal of this paper is to present the range of miniature interstitial applicators we developed at INSERM for various applications. The sources are rotating plane water-cooled transducers that operate at a frequency between 3 and 10 MHz depending on the desired therapeutic depth. The choice of a plane transducer rather than divergent sources permits to extend the therapeutic depth and to enhance the angular selectivity of the treatment Rotating single element flat transducer can also be replaced by cylindrical arrays for rotating electronically a reconstructed plane wave. When extended zone of coagulation are required, original therapeutic modalities combining cavitation and thermal effects are used. These methods consist in favoring in depth heating by increasing the acoustic attenuation away from the transducer with the presence of bubbles. When associated to modern imaging modalities, these minimally invasive therapeutic devices offer very promising options for cancer treatment. For examples, two versions of an image-guided esophageal applicator are designed: one uses a retractable ultrasound mini probe for the positioning of the applicator, while the other is MRI compatible and offers on line monitoring of temperature. Beyond these engineering considerations, our clinical experience demonstrates that following interstitial routes for applying HIFU is an interesting therapeutic option when targeted sites cannot be reached from outside the patient.

Is being a medical educator a lonely business? The essence of social support.

PubMed

van den Berg, Joost W; Verberg, Christel P M; Scherpbier, Albert J J A; Jaarsma, A Debbie C; Lombarts, Kiki M J M H

2017-03-01

Social support helps prevent burnout and promotes its positive opposite, work engagement. With higher work engagement performance increases. The context-specific aspects of social support for medical educators, in their educator role, are unknown. To help facilitate social support our study describes the essential elements of social support and their meaning for medical educators. We held interviews with medical educators purposefully sampled for diverse backgrounds and working circumstances and who spent a considerable amount of time on education. Both clinicians and basic scientists participated. The Pictor technique guided the interviews. Participants were invited to talk about the breadth of social support and elaborate on meaningful experiences. Template analysis was used for a descriptive phenomenological approach. Thirteen medical educators were interviewed. We identified four themes: (i) sources of support and their intent (e.g. a superior with the intent to stimulate personal growth); (ii) the materialisation of support (e.g. sought or offered); (iii) its manifestation (e.g. the act of providing protected time); and (iv) the overarching effect of social support, both in terms of practical effects and the meaning of support. We identified three sorts of meanings of social support for educators. Receiving support could lead to (i) feeling reassured and confident; (ii) feeling encouraged and determined and (iii) a sense of relatedness and acknowledgement of the educator role. Support for education comes from a wide range of sources because it is both sought and offered beyond the boundaries of the educational role. The resulting differences in support provided necessitate that educational leaders and policymakers consider the sources available to each educator, connecting educators where necessary. When facilitating or designing social support it is important that the need to feel reassured, encouraged or related is met. © 2017 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

High Power LaB6 Plasma Source Performance for the Lockheed Martin Compact Fusion Reactor Experiment

NASA Astrophysics Data System (ADS)

Heinrich, Jonathon

2016-10-01

Lockheed Martin's Compact Fusion Reactor (CFR) concept is a linear encapsulated ring cusp. Due to the complex field geometry, plasma injection into the device requires careful consideration. A high power thermionic plasma source (>0.25MW; >10A/cm2) has been developed with consideration to phase space for optimal coupling. We present the performance of the plasma source, comparison with alternative plasma sources, and plasma coupling with the CFR field configuration. ©2016 Lockheed Martin Corporation. All Rights Reserved.

Gene and protein nomenclature in public databases

PubMed Central

Fundel, Katrin; Zimmer, Ralf

2006-01-01

Background Frequently, several alternative names are in use for biological objects such as genes and proteins. Applications like manual literature search, automated text-mining, named entity identification, gene/protein annotation, and linking of knowledge from different information sources require the knowledge of all used names referring to a given gene or protein. Various organism-specific or general public databases aim at organizing knowledge about genes and proteins. These databases can be used for deriving gene and protein name dictionaries. So far, little is known about the differences between databases in terms of size, ambiguities and overlap. Results We compiled five gene and protein name dictionaries for each of the five model organisms (yeast, fly, mouse, rat, and human) from different organism-specific and general public databases. We analyzed the degree of ambiguity of gene and protein names within and between dictionaries, to a lexicon of common English words and domain-related non-gene terms, and we compared different data sources in terms of size of extracted dictionaries and overlap of synonyms between those. The study shows that the number of genes/proteins and synonyms covered in individual databases varies significantly for a given organism, and that the degree of ambiguity of synonyms varies significantly between different organisms. Furthermore, it shows that, despite considerable efforts of co-curation, the overlap of synonyms in different data sources is rather moderate and that the degree of ambiguity of gene names with common English words and domain-related non-gene terms varies depending on the considered organism. Conclusion In conclusion, these results indicate that the combination of data contained in different databases allows the generation of gene and protein name dictionaries that contain significantly more used names than dictionaries obtained from individual data sources. Furthermore, curation of combined dictionaries considerably increases size and decreases ambiguity. The entries of the curated synonym dictionary are available for manual querying, editing, and PubMed- or Google-search via the ProThesaurus-wiki. For automated querying via custom software, we offer a web service and an exemplary client application. PMID:16899134

4D volcano gravimetry

USGS Publications Warehouse

Battaglia, Maurizio; Gottsmann, J.; Carbone, D.; Fernandez, J.

2008-01-01

Time-dependent gravimetric measurements can detect subsurface processes long before magma flow leads to earthquakes or other eruption precursors. The ability of gravity measurements to detect subsurface mass flow is greatly enhanced if gravity measurements are analyzed and modeled with ground-deformation data. Obtaining the maximum information from microgravity studies requires careful evaluation of the layout of network benchmarks, the gravity environmental signal, and the coupling between gravity changes and crustal deformation. When changes in the system under study are fast (hours to weeks), as in hydrothermal systems and restless volcanoes, continuous gravity observations at selected sites can help to capture many details of the dynamics of the intrusive sources. Despite the instrumental effects, mainly caused by atmospheric temperature, results from monitoring at Mt. Etna volcano show that continuous measurements are a powerful tool for monitoring and studying volcanoes.Several analytical and numerical mathematical models can beused to fit gravity and deformation data. Analytical models offer a closed-form description of the volcanic source. In principle, this allows one to readily infer the relative importance of the source parameters. In active volcanic sites such as Long Valley caldera (California, U.S.A.) and Campi Flegrei (Italy), careful use of analytical models and high-quality data sets has produced good results. However, the simplifications that make analytical models tractable might result in misleading volcanological inter-pretations, particularly when the real crust surrounding the source is far from the homogeneous/ isotropic assumption. Using numerical models allows consideration of more realistic descriptions of the sources and of the crust where they are located (e.g., vertical and lateral mechanical discontinuities, complex source geometries, and topography). Applications at Teide volcano (Tenerife) and Campi Flegrei demonstrate the importance of this more realistic description in gravity calculations. ?? 2008 Society of Exploration Geophysicists. All rights reserved.

The use of hydrogen for aircraft propulsion in view of the fuel crisis

NASA Technical Reports Server (NTRS)

Weiss, S.

1973-01-01

Some factors influencing the technical feasibility of operating a liquid hydrogen-fueled airplane are discussed in light of the projected decrease of fossil fuels. Other sources of energy, such as wind, tidal, solar, and geothermal, are briefly mentioned. In view of projected decreases in available petroleum fuels, interest has been generated in exploiting the potential of liquid hydrogen (LH2) as an aircraft fuel. Cost studies of LH2 production show it to be more expensive than presently used fuels. Regardless of cost considerations, LH2 is viewed as an attractive aircraft fuel because of the potential performance benefits it offers. Accompanying these benefits, however, are many new problems associated with aircraft design and operations; for example, problems related to fuel system design and the handling of LH2 during ground servicing. Some of the factors influencing LH2 fuel tank design, pumping, heat exchange, and flow regulation are discussed.

Beyond the corporeal: Extending propertisation of body parts to derivative information.

PubMed

Bonython, Wendy; Arnold, Bruce Baer

2016-03-01

Jurisprudential consideration of property in the human body has typically conceptualised it as tangible, of finite lifespan, with limited end uses. This article offers an alternative conceptualisation: the body as information--intangible, infinite, and perpetual. Global markets in health "big data"--including population genomic data--trade this information. Emerging jurisprudence on source rights in this information are derived from jurisprudence based on the traditional, tangible, finite conceptualisation of the body--itself controversial--criticised in part for disregarding property rights vesting in the self, while recognising them in strangers. As such, it provides an uncertain foundation for extension to govern rights over derivatives, enabling disregard of legitimate concerns about health, commercialisation and genetic privacy, concerns compounded by the intergenerational nature of genetic information. A more nuanced approach, recognising that donors and strangers alike hold only weak custodial rights over access, use, and dissemination of tissues and derivative information, is required.

The bacterial skin microbiome in psoriatic arthritis, an unexplored link in pathogenesis: challenges and opportunities offered by recent technological advances.

PubMed

Castelino, Madhura; Eyre, Stephen; Upton, Mathew; Ho, Pauline; Barton, Anne

2014-05-01

The resident microbial community, harboured by humans in sites such as the skin and gastrointestinal tract, is enormous, representing a candidate environmental factor affecting susceptibility to complex diseases, where both genetic and environmental risk factors are important. The potential of microorganisms to influence the human immune system is considerable, given their ubiquity. The impact of the host-gene-microbe interaction on the maintenance of health and the development of disease has not yet been assessed robustly in chronic inflammatory conditions. PsA represents a model inflammatory disease to explore the role of the microbiome because skin involvement and overlap with IBD implicates both the skin and gastrointestinal tract as sources of microbial triggers for PsA. In parallel with genetic studies, characterization of the host microbiota may benefit our understanding of the microbial contribution to disease pathogenesis-knowledge that may eventually inform the development of novel therapeutics.

White Ethnic Residential Segregation in Historical Perspective: U.S. Cities in 1880

PubMed Central

Logan, John R.; Zhang, Weiwei

2013-01-01

Investigating immigrant residential patterns in 1880 offers a baseline for understanding residential assimilation trajectories in subsequent eras. This study uses 100% count information from the 1880 Census to estimate a multilevel model of ethnic isolation and exposure to native whites in 67 cities for individual Irish, German and British residents. At the individual level, the key predictors are drawn from assimilation theory: nativity, occupation, and marital status. The multilevel model makes it possible to control for these predictors and to study independent sources of variation in segregation across cities. There is considerable variation at the city level, especially due to differences in the relative sizes of groups. Other significant city-level predictors of people’s neighborhood composition include the share of group members who are foreign-born, the disparity in occupational standing between group members and native whites, and the degree of occupational segregation between them. PMID:23017933

Exploring clinical wisdom in nursing education.

PubMed

McKie, Andrew; Baguley, Fiona; Guthrie, Caitrian; Jackson, Carol; Kirkpatrick, Pamela; Laing, Adele; O'Brien, Stephen; Taylor, Ruth; Wimpenny, Peter

2012-03-01

The recent interest in wisdom in professional health care practice is explored in this article. Key features of wisdom are identified via consideration of certain classical, ancient and modern sources. Common themes are discussed in terms of their contribution to 'clinical wisdom' itself and this is reviewed against the nature of contemporary nursing education. The distinctive features of wisdom (recognition of contextual factors, the place of the person and timeliness) may enable their significance for practice to be promoted in more coherent ways in nursing education. Wisdom as practical knowledge (phronesis) is offered as a complementary perspective within the educational preparation and practice of students of nursing. Certain limitations within contemporary UK nursing education are identified that may inhibit development of clinical wisdom. These are: the modularization of programmes in higher education institutions, the division of pastoral and academic support and the relationship between theory and practice.

Hybrid energy storage systems utilizing redox active organic compounds

DOEpatents

Wang, Wei; Xu, Wu; Li, Liyu; Yang, Zhenguo

2015-09-08

Redox flow batteries (RFB) have attracted considerable interest due to their ability to store large amounts of power and energy. Non-aqueous energy storage systems that utilize at least some aspects of RFB systems are attractive because they can offer an expansion of the operating potential window, which can improve on the system energy and power densities. One example of such systems has a separator separating first and second electrodes. The first electrode includes a first current collector and volume containing a first active material. The second electrode includes a second current collector and volume containing a second active material. During operation, the first source provides a flow of first active material to the first volume. The first active material includes a redox active organic compound dissolved in a non-aqueous, liquid electrolyte and the second active material includes a redox active metal.

Automobiles and global warming: Alternative fuels and other options for carbon dioxide emissions reduction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sagar, A.D.

Automobiles are a source of considerable pollution at the global level, including a significant fraction of the total greenhouse gas emissions. Alternative fuels have received some attention as potential options to curtail the carbon dioxide emissions from motor vehicles. This article discusses the feasibility and desirability (from a technical as well as a broader environmental perspective) of the large-scale production and use of alternative fuels as a strategy to mitigate automotive carbon dioxide emissions. Other options such as improving vehicle efficiency and switching to more efficient modes of passenger transportation are also discussed. These latter options offer an effective andmore » immediate way to tackle the greenhouse and other pollutant emission from automobiles, especially as the limitations of currently available alternative fuels and the technological and other constraints for potential future alternatives are revealed.« less

Cellular Level Brain Imaging in Behaving Mammals: An Engineering Approach

PubMed Central

Hamel, Elizabeth J.O.; Grewe, Benjamin F.; Parker, Jones G.; Schnitzer, Mark J.

2017-01-01

Fluorescence imaging offers expanding capabilities for recording neural dynamics in behaving mammals, including the means to monitor hundreds of cells targeted by genetic type or connectivity, track cells over weeks, densely sample neurons within local microcircuits, study cells too inactive to isolate in extracellular electrical recordings, and visualize activity in dendrites, axons, or dendritic spines. We discuss recent progress and future directions for imaging in behaving mammals from a systems engineering perspective, which seeks holistic consideration of fluorescent indicators, optical instrumentation, and computational analyses. Today, genetically encoded indicators of neural Ca2+ dynamics are widely used, and those of trans-membrane voltage are rapidly improving. Two complementary imaging paradigms involve conventional microscopes for studying head-restrained animals and head-mounted miniature microscopes for imaging in freely behaving animals. Overall, the field has attained sufficient sophistication that increased cooperation between those designing new indicators, light sources, microscopes, and computational analyses would greatly benefit future progress. PMID:25856491

Ethics of medical records and professional communications.

PubMed

Recupero, Patricia R

2008-01-01

In child and adolescent psychiatry, medical records and professional communications raise important ethical concerns for the treating or consulting clinician. Although a distinction may be drawn between internal records (eg, medical records and psychotherapy notes) and external communications (eg, consultation reports and correspondence with pediatricians), several ethical principles apply to both types of documentation; however, specific considerations may vary, depending upon the context in which the records or communications were produced. Special care is due with regard to thoroughness and honesty, collaboration and cooperation, autonomy and dignity of the patient, confidentiality of the patient and family members, maintaining objectivity and neutrality, electronic communications media, and professional activities (eg, political advocacy). This article reviews relevant ethical concerns for child and adolescent psychiatrists with respect to medical records and professional communications, drawing heavily from forensic and legal sources, and offers additional recommendations for further reading for clarification and direction on ethical dilemmas.

Patient Electronic Health Records as a Means to Approach Genetic Research in Gastroenterology

PubMed Central

Ananthakrishnan, Ashwin N; Lieberman, David

2015-01-01

Electronic health records (EHR) are being increasingly utilized and form a unique source of extensive data gathered during routine clinical care. Through use of codified and free text concepts identified using clinical informatics tools, disease labels can be assigned with a high degree of accuracy. Analysis linking such EHR-assigned disease labels to a biospecimen repository has demonstrated that genetic associations identified in prospective cohorts can be replicated with adequate statistical power, and novel phenotypic associations identified. In addition, genetic discovery research can be performed utilizing clinical, laboratory, and procedure data obtained during care. Challenges with such research include the need to tackle variability in quality and quantity of EHR data and importance of maintaining patient privacy and data security. With appropriate safeguards, this novel and emerging field of research offers considerable promise and potential to further scientific research in gastroenterology efficiently, cost-effectively, and with engagement of patients and communities. PMID:26073373

Dynamical injections as the source of near geostationary quiet time particle spatial boundaries

NASA Technical Reports Server (NTRS)

Mauk, B. H.; Meng, C. I.

1983-01-01

The question whether the noon-dusk feature is a manifestation of the spatial structures that should arise from quasi-stationary convection is examined. The key consideration here is whether the energy dispersion of the feature can be explained. It is shown that the observed energy dispersion cannot be attributed to the standard stationary convection configurations, either perturbed or unperturbed. It is also demonstrated, using a detailed computer simulation, that the nighttime, double-spiral-shaped injection boundary (used previously to reproduce the fast changing nighttime features) is successful at reproducing the noon-dusk feature by allowing the particles to evolve for periods of 12 to 36 hours after the injection. It is stressed that the portion of the injection boundary responsible for the feature looks very different from the standard convection boundaries configuration. Conclusions are offered concerning the importance of quasi-stationary convection as the mechanism by which the near geostationary regions are populated.

40 CFR 194.53 - Consideration of underground sources of drinking water.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Consideration of underground sources of drinking water. 194.53 Section 194.53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS CRITERIA FOR THE CERTIFICATION AND RE-CERTIFICATION OF THE WASTE ISOLATION PILOT PLANT'S COMPLIANCE WITH THE...

40 CFR 194.53 - Consideration of underground sources of drinking water.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Consideration of underground sources of drinking water. 194.53 Section 194.53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS CRITERIA FOR THE CERTIFICATION AND RE-CERTIFICATION OF THE WASTE ISOLATION PILOT PLANT'S COMPLIANCE WITH THE...

Brain Activity in Fairness Consideration during Asset Distribution: Does the Initial Ownership Play a Role?

PubMed Central

Wu, Yin; Hu, Jie; van Dijk, Eric; Leliveld, Marijke C.; Zhou, Xiaolin

2012-01-01

Previous behavioral studies have shown that initial ownership influences individuals’ fairness consideration and other-regarding behavior. However, it is not entirely clear whether initial ownership influences the brain activity when a recipient evaluates the fairness of asset distribution. In this study, we randomly assigned the bargaining property (monetary reward) to either the allocator or the recipient in the ultimatum game and let participants of the study, acting as recipients, receive either disadvantageous unequal, equal, or advantageous unequal offers from allocators while the event-related potentials (ERPs) were recorded. Behavioral results showed that participants were more likely to reject disadvantageous unequal and equal offers when they initially owned the property as compared to when they did not. The two types of unequal offers evoked more negative going ERPs (the MFN) than the equal offers in an early time window and the differences were not modulated by the initial ownership. In a late time window, however, the P300 responses to division schemes were affected not only by the type of unequal offers but also by whom the property was initially assigned to. These findings suggest that while the MFN may function as a general mechanism that evaluates whether the offer is consistent or inconsistent with the equity rule, the P300 is sensitive to top-down controlled processes, into which factors related to the allocation of attentional resources, including initial ownership and personal interests, come to play. PMID:22761850

Alma Mater: Design and Experience in the Women's Colleges from Their Nineteenth-Century Beginnings to the 1930s.

ERIC Educational Resources Information Center

Horowitz, Helen Lefkowitz

The creation and development of 10 women's colleges are discussed: Mount Holyoke, Vassar, Wellesley, Smith, Radcliffe, Bryn Mawr, and Barnard (the Seven Sisters colleges), and Sarah Lawrence, Bennington, and Scripps. Consideration is given to: how each of these colleges offered to women an education equal to that offered by the best men's…

Adaptive Driving Equipment: Selection and Major Considerations [and] Battery Powered Scooters and 3-Wheelers. Information Support Packets #1 and #2.

ERIC Educational Resources Information Center

Stevens, John H.

Two brief guides offer suggestions for persons with physical disabilities who are considering the purchase of adaptive driving equipment, battery-powered scooters, or three wheelers. The first guide offers guidelines for individuals considering purchase of special hand controls or other modifications or a van lift to enhance their independence in…

Considerations and Recommendations for Implementing a Dual-Enrollment Program: Bridging the Gap between High School and College Level Science

ERIC Educational Resources Information Center

Lukes, Laura A.

2014-01-01

Dual-enrollment (DE) science courses offer a way to strengthen the science, technology, engineering, and mathematics pipeline between high school and college. These courses offer high school students the opportunity to experience college science in a more supported environment, allowing them to adjust to the different academic and social demands…

One dozen considerations when working with women in substance abuse groups.

PubMed

Bright, Charlotte Lyn; Osborne, Victoria A; Greif, Geoffrey L

2011-01-01

Women and men have different histories, presentations, and behaviors in substance abuse groups. Twelve considerations are offered for the beginning group leader when encountering women with substance abuse issues. These include understanding sexism, what brings women to treatment, and how women behave in group treatment. Implications for clinical practice with women in single-gender and mixed-gender groups are included.

Alcohol advertising and adolescents.

PubMed

Strasburger, Victor C

2002-04-01

Considerable research now exists that the media may exert a powerful influence on adolescents' drug-taking behavior. Teens view an average of 2,000 beer and wine ads per year in the US. In addition, television shows, movies, and music videos contain considerable amounts of alcohol use. This article will discuss the available research and offers suggestions to make the media healthier for teenagers.

At-Risk Youth: Considerations for State-Level Policymakers, Including a Summary of Recent State-Level Actions in the Region.

ERIC Educational Resources Information Center

Regional Laboratory for Educational Improvement of the Northeast & Islands, Andover, MA.

In response to the growing dropout problem, most of the northeastern states (and islands) and many of their local districts have implemented policies and programs designed to reduce the number of students leaving school. This paper presents some observations, culled from various reports, for policymakers' consideration. Section I offers a set of…

Effects of land cover, topography, and built structure on seasonal water quality at multiple spatial scales.

PubMed

Pratt, Bethany; Chang, Heejun

2012-03-30

The relationship among land cover, topography, built structure and stream water quality in the Portland Metro region of Oregon and Clark County, Washington areas, USA, is analyzed using ordinary least squares (OLS) and geographically weighted (GWR) multiple regression models. Two scales of analysis, a sectional watershed and a buffer, offered a local and a global investigation of the sources of stream pollutants. Model accuracy, measured by R(2) values, fluctuated according to the scale, season, and regression method used. While most wet season water quality parameters are associated with urban land covers, most dry season water quality parameters are related topographic features such as elevation and slope. GWR models, which take into consideration local relations of spatial autocorrelation, had stronger results than OLS regression models. In the multiple regression models, sectioned watershed results were consistently better than the sectioned buffer results, except for dry season pH and stream temperature parameters. This suggests that while riparian land cover does have an effect on water quality, a wider contributing area needs to be included in order to account for distant sources of pollutants. Copyright © 2012 Elsevier B.V. All rights reserved.

Media(ted) fabrications: how the science-media symbiosis helped 'sell' cord banking.

PubMed

Michelle, Carolyn

2006-01-01

This paper considers the problematic role of the science-media symbiosis in the dissemination of misleading and emotionally manipulative information regarding services offered by CordBank, New Zealand's only umbilical cord blood banking facility. As this case study illustrates, the growing reliance of health and science reporters on the knowledge capital of medical specialists, biogenetic researchers, and scientists potentially enhances the ability of 'expert' sources to set the agenda for media representations of emerging medical and scientific developments, and may undermine the editorial independence of journalists and editors, many of whom in this case failed to critically evaluate deeply problematic claims regarding the current and future benefits of cord banking. Heavy reliance on established media frames of anecdotal personalization and technoboosterism also reinforced a proscience journalistic culture in which claims by key sources were uncritically reiterated and amplified, with journalistic assessments of the value of cord banking emphasizing potential benefits for individual consumers. It is argued that use of these media frames potentially detracts from due consideration of the broader social, ethical, legal, and health implications of emerging biomedical developments, along with the professional, personal, and increasingly also financial interests at stake in their public promotion, given the growing commercialization of biogenetic technologies.

The Case against Preadoption Genetic Testing.

ERIC Educational Resources Information Center

Freundlich, Madelyn D.

1998-01-01

Examines the medical, psychosocial, and ethical considerations concerning presymptomatic genetic testing in evaluating children for adoption. Offers an ethical framework for rejecting such a practice. (JPB)

THz optical design considerations and optimization for medical imaging applications

NASA Astrophysics Data System (ADS)

Sung, Shijun; Garritano, James; Bajwa, Neha; Nowroozi, Bryan; Llombart, Nuria; Grundfest, Warren; Taylor, Zachary D.

2014-09-01

THz imaging system design will play an important role making possible imaging of targets with arbitrary properties and geometries. This study discusses design consideration and imaging performance optimization techniques in THz quasioptical imaging system optics. Analysis of field and polarization distortion by off-axis parabolic (OAP) mirrors in THz imaging optics shows how distortions are carried in a series of mirrors while guiding the THz beam. While distortions of the beam profile by individual mirrors are not significant, these effects are compounded by a series of mirrors in antisymmetric orientation. It is shown that symmetric orientation of the OAP mirror effectively cancels this distortion to recover the original beam profile. Additionally, symmetric orientation can correct for some geometrical off-focusing due to misalignment. We also demonstrate an alternative method to test for overall system optics alignment by investigating the imaging performance of the tilted target plane. Asymmetric signal profile as a function of the target plane's tilt angle indicates when one or more imaging components are misaligned, giving a preferred tilt direction. Such analysis can offer additional insight into often elusive source device misalignment at an integrated system. Imaging plane tilting characteristics are representative of a 3-D modulation transfer function of the imaging system. A symmetric tilted plane is preferred to optimize imaging performance.

The pursuit of Leadership in Energy and Environmental Design (LEED) certification for campus housing at public universities

NASA Astrophysics Data System (ADS)

Konvalinka, April Hicks

This dissertation identifies the reasons why institutions of higher education pursue Leadership in Energy and Environmental Design (LEED) certification for new construction of campus housing. The research was guided by three questions: 1. Why did the institution choose to pursue LEED certification for campus housing? 2. What considerations should be made in the design, development, and planning process of a LEED residence hall? 3. What significant impact has the LEED residence hall made on campus? The outcomes of this study will provide insight to university and housing administrators who are considering pursuit of LEED certification for new residence hall development. The primary sources of data are chief housing officers or their designees at public four-year colleges and universities with new campus housing awarded LEED certification. Qualitative research techniques were used to conduct interviews by LEED certification level: Platinum, Silver, Gold, and Certified. Data collection ended when data saturation of each question in each certification level was achieved. This dissertation offers reasons why universities pursue LEED certification: state requirement, institutional commitment, institutional standard, environmental stewardship, departmental decision, and student interest. Additionally, considerations and lessons learned from the pursuit of LEED certification have been identified and can serve as a guide to housing administrators who aim to achieve any LEED level certification.

Incorporation of epidemiological findings into radiation protection standards.

PubMed

Goldsmith, J R

In standard setting there is a tendency to use data from experimental studies in preference to findings from epidemiological studies. Yet the epidemiological studies are usually the first and at times the only source of data on such critical effects as cancer, reproductive failure, and chronic cardiac and cardiovascular disease in exposed humans. A critique of the protection offered by current and proposed standards for ionizing and non-ionizing radiation illustrates some of the problems. Similar problems occur with water and air pollutants and with occupational exposures of many types. The following sorts of problems were noted: (a) Consideration of both thermal and non-thermal effects especially of non-ionizing radiation. (b) Interpretation of non-significant results as equivalent to no effect. (c) Accepting author's interpretation of a study, rather than examining its data independently for evidence of hazard. (d) Discounting data on unanticipated effects because of poor fit to preconceptions. (e) Dependence on threshold assumptions and demonstrations of dose-response relationships. (f) Choice of insensitive epidemiological indicators and procedures. (g) Consideration of each study separately, rather than giving weight to the conjunction of evidence from all available studies. These problems may be minimized by greater involvement of epidemiologists and their professional organizations in decisions about health protection.

Seasonal forecasting of high wind speeds over Western Europe

NASA Astrophysics Data System (ADS)

Palutikof, J. P.; Holt, T.

2003-04-01

As financial losses associated with extreme weather events escalate, there is interest from end users in the forestry and insurance industries, for example, in the development of seasonal forecasting models with a long lead time. This study uses exceedences of the 90th, 95th, and 99th percentiles of daily maximum wind speed over the period 1958 to present to derive predictands of winter wind extremes. The source data is the 6-hourly NCEP Reanalysis gridded surface wind field. Predictor variables include principal components of Atlantic sea surface temperature and several indices of climate variability, including the NAO and SOI. Lead times of up to a year are considered, in monthly increments. Three regression techniques are evaluated; multiple linear regression (MLR), principal component regression (PCR), and partial least squares regression (PLS). PCR and PLS proved considerably superior to MLR with much lower standard errors. PLS was chosen to formulate the predictive model since it offers more flexibility in experimental design and gave slightly better results than PCR. The results indicate that winter windiness can be predicted with considerable skill one year ahead for much of coastal Europe, but that this deteriorates rapidly in the hinterland. The experiment succeeded in highlighting PLS as a very useful method for developing more precise forecasting models, and in identifying areas of high predictability.

Phytochemica: a platform to explore phytochemicals of medicinal plants.

PubMed

Pathania, Shivalika; Ramakrishnan, Sai Mukund; Bagler, Ganesh

2015-01-01

Plant-derived molecules (PDMs) are known to be a rich source of diverse scaffolds that could serve as the basis for rational drug design. Structured compilation of phytochemicals from traditional medicinal plants can facilitate prospection for novel PDMs and their analogs as therapeutic agents. Atropa belladonna, Catharanthus roseus, Heliotropium indicum, Picrorhiza kurroa and Podophyllum hexandrum are important Himalayan medicinal plants, reported to have immense therapeutic properties against various diseases. We present Phytochemica, a structured compilation of 963 PDMs from these plants, inclusive of their plant part source, chemical classification, IUPAC names, SMILES notations, physicochemical properties and 3-dimensional structures with associated references. Phytochemica is an exhaustive resource of natural molecules facilitating prospection for therapeutic molecules from medicinally important plants. It also offers refined search option to explore the neighbourhood of chemical space against ZINC database to identify analogs of natural molecules at user-defined cut-off. Availability of phytochemical structured dataset may enable their direct use in in silico drug discovery which will hasten the process of lead identification from natural products under proposed hypothesis, and may overcome urgent need for phytomedicines. Compilation and accessibility of indigenous phytochemicals and their derivatives can be a source of considerable advantage to research institutes as well as industries. home.iitj.ac.in/∼bagler/webservers/Phytochemica. © The Author(s) 2015. Published by Oxford University Press.

Increase in Efficiency of Use of Pedestrian Radiation Portal Monitors

NASA Astrophysics Data System (ADS)

Solovev, D. B.; Merkusheva, A. E.

2017-11-01

Most international airports in the world use radiation portal monitors (RPM) for primary radiation control organization. During the exploitation pedestrian radiation portal monitors operators (in the Russian Federation it is a special subdivision of customs officials) have certain problems related to the search of an ionizing radiation source causing the alarm signal of a radiation monitor. Radiation portal monitors at standard (factory) settings have to find out the illegal moving of the radioisotopes moved by physical persons passing through a controlled zone and having a steady radiation by the gamma or neutron channel. The problem is that recently the number of the ownerships who underwent treatment or medical diagnostics with the use of radio pharmaceuticals considerably increased, i.e,. ownerships represent such an ionizing radiation source. The operator of the radiation portal monitor has to define very quickly whether the ownership is a violator (takes unsolved radioisotopes illegally) or is just a patient of the clinic who underwent treatment/diagnostics with the use of radio pharmaceuticals. The research showing the radioisotopes which are most often used in the medical purposes are given in article, it is offered to use the new software developed by the authors allowing the operator of the radiation portal monitor to define the location of the ownership which has such ionizing radiation source by the activity of radiation similar to the radiation from radio pharmaceuticals.

The role of objective personality inventories in suicide risk assessment: an evaluation and proposal.

PubMed

Johnson, W B; Lall, R; Bongar, B; Nordlund, M D

1999-01-01

Objective personality assessment instruments offer a comparatively underutilized source of clinical data in attempts to evaluate and predict risk for suicide. In contrast to focal suicide risk measures, global personality inventories may be useful in identification of long-standing styles that predispose persons to eventual suicidal behavior. This article reviews the empirical literature regarding the efficacy of established personality inventories in predicting suicidality. The authors offer several recommendations for future research with these measures and conclude that such objective personality instruments offer only marginal utility as sources of clinical information in comprehensive suicide risk evaluations. Personality inventories may offer greatest utility in long-term assessment of suicide risk.

New LNG process scheme

DOE Office of Scientific and Technical Information (OSTI.GOV)

Foglietta, J.H.

1999-07-01

A new LNG cycle has been developed for base load liquefaction facilities. This new design offers a different technical and economical solution comparing in efficiency with the classical technologies. The new LNG scheme could offer attractive business opportunities to oil and gas companies that are trying to find paths to monetize gas sources more effectively; particularly for remote or offshore locations where smaller scale LNG facilities might be applicable. This design offers also an alternative route to classic LNG projects, as well as alternative fuel sources. Conceived to offer simplicity and access to industry standard equipment, This design is amore » hybrid result of combining a standard refrigeration system and turboexpander technology.« less

Wave field synthesis of moving virtual sound sources with complex radiation properties.

PubMed

Ahrens, Jens; Spors, Sascha

2011-11-01

An approach to the synthesis of moving virtual sound sources with complex radiation properties in wave field synthesis is presented. The approach exploits the fact that any stationary sound source of finite spatial extent radiates spherical waves at sufficient distance. The angular dependency of the radiation properties of the source under consideration is reflected by the amplitude and phase distribution on the spherical wave fronts. The sound field emitted by a uniformly moving monopole source is derived and the far-field radiation properties of the complex virtual source under consideration are incorporated in order to derive a closed-form expression for the loudspeaker driving signal. The results are illustrated via numerical simulations of the synthesis of the sound field of a sample moving complex virtual source.

Community rehabilitation of disabled with a focus on blind persons: Indian perspective

PubMed Central

Jose, R; Sachdeva, Sandeep

2010-01-01

India, the largest democratic country in the world, is marching ahead strongly on the growth and developmental front and is poised to be the leader in the market economy. This role creates and increases far greater responsibilities on us in ensuring that the benefit of the developmental cycle reaches each and every citizen of this country, including the able and the disabled ones. It has been enshrined in the Constitution of India to ensure equality, freedom, justice, and dignity of all individuals and implicitly mandates an inclusive society. With increase in consideration of quality parameters in all spheres of life including availability, access, and provision of comprehensive services to the disabled, it is pertinent to have a look on the contribution of government in keeping the aspiration and commitment towards common people. The article attempts to review the concept of rehabilitation for the disabled keeping a focus on the blind person, and list out the activities, programs/schemes, institutional structure and initiatives taken by the Government of India (GOI) for the same and the incentives/benefits extended to blind persons. The article concludes by reiterating the importance of individual need assessment and mentioning new initiatives proposed on Low Vision services in the approved 11th plan under National Programme for Control of Blindness (NPCB). The source of information has been annual reports, notification and the approved 11th five-year plan of GOI, articles published with key words like rehabilitation, disability, assistive devices, low vision aids, and/or blind person through the mode of Internet. Annexure provides a list of selected institutions in the country offering Low Vision services compiled from various sources through personal communication and an approved list of training institutes under NPCB, GOI offering Low Vision training. PMID:20195037

Community rehabilitation of disabled with a focus on blind persons: Indian perspective.

PubMed

Jose, R; Sachdeva, Sandeep

2010-01-01

India, the largest democratic country in the world, is marching ahead strongly on the growth and developmental front and is poised to be the leader in the market economy. This role creates and increases far greater responsibilities on us in ensuring that the benefit of the developmental cycle reaches each and every citizen of this country, including the able and the disabled ones. It has been enshrined in the Constitution of India to ensure equality, freedom, justice, and dignity of all individuals and implicitly mandates an inclusive society. With increase in consideration of quality parameters in all spheres of life including availability, access, and provision of comprehensive services to the disabled, it is pertinent to have a look on the contribution of government in keeping the aspiration and commitment towards common people. The article attempts to review the concept of rehabilitation for the disabled keeping a focus on the blind person, and list out the activities, programs/schemes, institutional structure and initiatives taken by the Government of India (GOI) for the same and the incentives/benefits extended to blind persons. The article concludes by reiterating the importance of individual need assessment and mentioning new initiatives proposed on Low Vision services in the approved 11th plan under National Programme for Control of Blindness (NPCB). The source of information has been annual reports, notification and the approved 11th five-year plan of GOI, articles published with key words like rehabilitation, disability, assistive devices, low vision aids, and/or blind person through the mode of Internet. Annexure provides a list of selected institutions in the country offering Low Vision services compiled from various sources through personal communication and an approved list of training institutes under NPCB, GOI offering Low Vision training.

Historical nectar assessment reveals the fall and rise of Britain in bloom

PubMed Central

Baude, Mathilde; Kunin, William E.; Boatman, Nigel D.; Conyers, Simon; Davies, Nancy; Gillespie, Mark A. K.; Morton, R. Daniel; Smart, Simon M.; Memmott, Jane

2015-01-01

Summary There is considerable concern over declines in insect pollinator communities and potential impacts on the pollination of crops and wildflowers1–4. Among the multiple pressures facing pollinators2–4, decreasing floral resources due to habitat loss and degradation has been suggested as a key contributing factor2–8. However, a lack of quantitative data has hampered testing for historical changes in floral resources. Here we show that overall floral rewards can be estimated at a national scale by combining vegetation surveys and direct nectar measurements. We find evidence for substantial losses in nectar resources in England and Wales between the 1930s and 1970s; however, total nectar provision in Great Britain as a whole had stabilised by 1978, and increased from 1998 to 2007. These findings concur with trends in pollinator diversity, which declined in the mid-20th century9 but stabilised more recently10. The diversity of nectar sources declined from 1978 to 1990 but stabilised thereafter at low levels, with four plant species accounting for over 50% of national nectar provision in 2007. Calcareous grassland, broadleaved woodland and neutral grassland are the habitats that produce the greatest amount of nectar per unit area from the most diverse sources, whereas arable land is the poorest in both respects. While agri-environment schemes add resources to arable landscapes, their national contribution is low. Due to their large area, improved grasslands could add substantially to national nectar provision if they were managed to increase floral resource provision. This national-scale assessment of floral resource provision brings new insights into the links between plant and pollinator declines, and offers considerable opportunities for conservation. PMID:26842058

A Comprehensive Review of Credit Instructional Programs Offered by Pasadena City Colleges, 1981-1982. Volume I. Summary Report.

ERIC Educational Resources Information Center

Carvell Education Managment Planning, Inc., Los Angeles, CA.

The first part of a report on a comprehensive review of the credit instructional programs offered by Pasadena City College (PCC), this volume provides a description of the evaluation procedures used, and a discussion of general issues that are major considerations for program improvement. Section I introduces the program review in terms of its…

Clarifying Resilience in the Context of Homeland Security

DTIC Science & Technology

2013-03-01

Resilience Is a Complex Adaptive System of Systems ( CASoS ) ....60 4. Resilience Is Experienced and Demonstrated in Different Ways ..60 5. Resilience Is...The inclusion of a resilience module into existing homeland security training programs broadens the practitioner’s knowledge base from a basic level...psychology offer several considerations for the homeland security practitioner. The first consideration maintains that a de -emphasis on the

Computer science security research and human subjects: emerging considerations for research ethics boards.

PubMed

Buchanan, Elizabeth; Aycock, John; Dexter, Scott; Dittrich, David; Hvizdak, Erin

2011-06-01

This paper explores the growing concerns with computer science research, and in particular, computer security research and its relationship with the committees that review human subjects research. It offers cases that review boards are likely to confront, and provides a context for appropriate consideration of such research, as issues of bots, clouds, and worms enter the discourse of human subjects review.

Effect of delayed wrapping and wrapping source on nitrogen balance and blood urea nitrogen in gestating sheep offered alfalfa silage

USDA-ARS?s Scientific Manuscript database

Exposing ensiled forage to oxygen can result in DM deterioration and reduce silage intake by animals. This study was conducted to investigate the effects of 2 different wrapping sources and time intervals between baling and wrapping on N balance and blood urea N in gestating sheep offered alfalfa si...

An analysis of job placement patterns of black and non-black male and female undergraduates at the University of Virginia and Hampton Institute. Ph.D. Thesis - Virginia Univ.

NASA Technical Reports Server (NTRS)

Anderson, A. F.

1974-01-01

Research questions were proposed to determine the relationship between independent variables (race, sex, and institution attended) and dependent variables (number of job offers received, salary received, and willingness to recommend source of employer contact). The control variables were academic major, grade point average, placement registration, nonemployment activity, employer, and source of employer contact. An analysis of the results revealed no statistical significance of the institution attended as a predictor of job offers or salary, although significant relationships were found between race and sex and number of job offers received. It was found that academic major, grade point average, and source of employer contact were more useful than race in the prediction of salary. Sex and nonemployment activity were found to be the most important variables in the model. The analysis also indicated that Black students received more job offers than non-Black students.

Using Deep Learning for Gamma Ray Source Detection at the First G-APD Cherenkov Telescope (FACT)

NASA Astrophysics Data System (ADS)

Bieker, Jacob

2018-06-01

Finding gamma-ray sources is of paramount importance for Imaging Air Cherenkov Telescopes (IACT). This study looks at using deep neural networks on data from the First G-APD Cherenkov Telescope (FACT) as a proof-of-concept of finding gamma-ray sources with deep learning for the upcoming Cherenkov Telescope Array (CTA). In this study, FACT’s individual photon level observation data from the last 5 years was used with convolutional neural networks to determine if one or more sources were present. The neural networks used various architectures to determine which architectures were most successful in finding sources. Neural networks offer a promising method for finding faint and extended gamma-ray sources for IACTs. With further improvement and modifications, they offer a compelling method for source detection for the next generation of IACTs.

Key Considerations of Community, Scalability, Supportability, Security, and Functionality in Selecting Open-Source Software in California Universities as Perceived by Technology Leaders

ERIC Educational Resources Information Center

Britton, Todd Alan

2014-01-01

Purpose: The purpose of this study was to examine the key considerations of community, scalability, supportability, security, and functionality for selecting open-source software in California universities as perceived by technology leaders. Methods: After a review of the cogent literature, the key conceptual framework categories were identified…

75 FR 34489 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-17

... report sales and use of proceeds in Regulation A offerings. We estimate that approximately 100 issuers... the use of automated collection techniques or other forms of information technology. Consideration...

Survey Shows Variation in Ph.D. Methods Training.

ERIC Educational Resources Information Center

Steeves, Leslie; And Others

1983-01-01

Reports on a 1982 survey of journalism graduate studies indicating considerable variation in research methods requirements and emphases in 23 universities offering doctoral degrees in mass communication. (HOD)

Early access programs: Benefits, challenges, and key considerations for successful implementation

PubMed Central

Patil, Sanjaykumar

2016-01-01

Early access programs, (EAPs) are adopted by an increasing number of pharma companies due to several benefits offered by these programs. EAPs offer ethical, compliant, and controlled mechanisms of access to investigational drugs outside of the clinical trial space and before the commercial launch of the drug, to patients with life-threatening diseases having no treatment options available. In addition to the development of positive relationships with key opinion leaders (KOL), patients, advocacy groups and regulators, the data captured from the implementation of EAPs supports in the formulation of global commercialization strategies. This white paper outlines various circumstances to be considered for the implementation of EAPs named patient programs, the regulatory landscape, the benefits and challenges associated with implementing these programs and the key considerations for their successful implementation. PMID:26955570

Brownfields Green Avenue Sites: Technical Memorandum - Conceptual Design for Sustainable Redevelopment

EPA Pesticide Factsheets

This technical memorandum briefly describes the site and proposed conceptual site plan, indicates conceptual design considerations, specifies recommended green and sustainable features, and offers other recommendations

The air, carbon, water synergies and trade-offs in China's natural gas industry

NASA Astrophysics Data System (ADS)

Qin, Y.; Mauzerall, D. L.; Höglund-Isaksson, L.; Wagner, F.; Byers, E.

2017-12-01

Both energy production and consumption can simultaneously affect regional air quality, local water stress, and the global climate. Identifying air, carbon and water impacts of various energy sources and end-uses is important in determining the relative merits of various energy policies. Here, we examine the air-carbon-water interdependencies of China's six major natural gas source choices (domestic conventional natural gas, domestic coal-based synthetic natural gas (SNG), domestic shale gas, imported liquefied natural gas, imported Russian pipeline gas, and imported Central Asian pipeline gas) and three end-use coal-to-gas deployment strategies (with substitution strategies that focus in turn on air quality, carbon, and water) in 2020. On the supply side, we find that gas sources other than SNG offer national air-carbon-water co-benefits. However, we find striking air-carbon/water trade-offs for SNG at the national scale. Moreover, the use of SNG significantly increases water demand and carbon emissions in regions already suffering from the most severe water stress and the highest per capita carbon footprint. On the end-use side, gas substitution for coal can result in enormous variations in air quality, carbon, and water impacts, with notable air-carbon synergies but air-water trade-offs. Our study finds that, except for SNG, end-use choices generally have a much larger influence on air quality, carbon emissions and water use than do gas source choices. Simultaneous consideration of air, carbon, and water impacts is necessary in designing both beneficial energy development and deployment policies.

Cyber-Terrorism and Cyber-Crime: There Is a Difference

DTIC Science & Technology

The terms cyber -terrorism and cyber -crime have many varying definitions depending on who is defining them. For example, individuals with expertise in...considerations and, when investigating a cyber -attack, procedural considerations. By examining the strengths and weaknesses of several definitions offered by...national security, law enforcement, industry, law, and scholars, this research constructs a list of parameters to consider when formulating definitions for cyber -terrorism and cyber -crime.

The Cambridge Garden House Hotel Riot of 1970 and Its Place in the History of British Student Protests

ERIC Educational Resources Information Center

Crook, David

2006-01-01

This article highlights a violent incident in the history of British student protests and outlines the judicial process that resulted. A wider consideration of student protests of the late 1960s and early 1970s, both in the UK and overseas is offered, together with some consideration of the significance of this particular case. At the time of the…

A Checklist for Identifying Funding Sources for Assistive Technology.

ERIC Educational Resources Information Center

Menlove, Martell

1996-01-01

This article offers a systematically organized series of questions to identify funding sources for assistive technology for students with disabilities. A decision tree links the questions with funding sources. (DB)

Developing open-source codes for electromagnetic geophysics using industry support

NASA Astrophysics Data System (ADS)

Key, K.

2017-12-01

Funding for open-source software development in academia often takes the form of grants and fellowships awarded by government bodies and foundations where there is no conflict-of-interest between the funding entity and the free dissemination of the open-source software products. Conversely, funding for open-source projects in the geophysics industry presents challenges to conventional business models where proprietary licensing offers value that is not present in open-source software. Such proprietary constraints make it easier to convince companies to fund academic software development under exclusive software distribution agreements. A major challenge for obtaining commercial funding for open-source projects is to offer a value proposition that overcomes the criticism that such funding is a give-away to the competition. This work draws upon a decade of experience developing open-source electromagnetic geophysics software for the oil, gas and minerals exploration industry, and examines various approaches that have been effective for sustaining industry sponsorship.

The Prepayment Dilemma: A Consumer's Guide from ALA.

ERIC Educational Resources Information Center

Laughrey, Edna; And Others

1977-01-01

Because prepayment problems have led to complaints from librarians, the Bookdealer-Library Relations Committee of the American Library Association offers considerations to serve as guidelines in making prepayment decisions. (JPF)

7 CFR 1468.20 - Application for CFO program participation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... program payments allowed, offering to apply more conservation practices to the land in order to increase... benefits; (4) Soil productivity; (5) Conservation compliance considerations; (6) Likelihood to remain in...

Technical and conceptual considerations for using animated stimuli in studies of animal behavior.

PubMed

Chouinard-Thuly, Laura; Gierszewski, Stefanie; Rosenthal, Gil G; Reader, Simon M; Rieucau, Guillaume; Woo, Kevin L; Gerlai, Robert; Tedore, Cynthia; Ingley, Spencer J; Stowers, John R; Frommen, Joachim G; Dolins, Francine L; Witte, Klaudia

2017-02-01

Rapid technical advances in the field of computer animation (CA) and virtual reality (VR) have opened new avenues in animal behavior research. Animated stimuli are powerful tools as they offer standardization, repeatability, and complete control over the stimulus presented, thereby "reducing" and "replacing" the animals used, and "refining" the experimental design in line with the 3Rs. However, appropriate use of these technologies raises conceptual and technical questions. In this review, we offer guidelines for common technical and conceptual considerations related to the use of animated stimuli in animal behavior research. Following the steps required to create an animated stimulus, we discuss (I) the creation, (II) the presentation, and (III) the validation of CAs and VRs. Although our review is geared toward computer-graphically designed stimuli, considerations on presentation and validation also apply to video playbacks. CA and VR allow both new behavioral questions to be addressed and existing questions to be addressed in new ways, thus we expect a rich future for these methods in both ultimate and proximate studies of animal behavior.

Technical and conceptual considerations for using animated stimuli in studies of animal behavior

PubMed Central

Rosenthal, Gil G.; Reader, Simon M.; Rieucau, Guillaume; Woo, Kevin L.; Gerlai, Robert; Tedore, Cynthia; Ingley, Spencer J.; Stowers, John R.; Frommen, Joachim G.; Dolins, Francine L.; Witte, Klaudia

2017-01-01

Abstract Rapid technical advances in the field of computer animation (CA) and virtual reality (VR) have opened new avenues in animal behavior research. Animated stimuli are powerful tools as they offer standardization, repeatability, and complete control over the stimulus presented, thereby “reducing” and “replacing” the animals used, and “refining” the experimental design in line with the 3Rs. However, appropriate use of these technologies raises conceptual and technical questions. In this review, we offer guidelines for common technical and conceptual considerations related to the use of animated stimuli in animal behavior research. Following the steps required to create an animated stimulus, we discuss (I) the creation, (II) the presentation, and (III) the validation of CAs and VRs. Although our review is geared toward computer-graphically designed stimuli, considerations on presentation and validation also apply to video playbacks. CA and VR allow both new behavioral questions to be addressed and existing questions to be addressed in new ways, thus we expect a rich future for these methods in both ultimate and proximate studies of animal behavior. PMID:29491958

Transportation systems health : concepts, applications & significance.

DOT National Transportation Integrated Search

2015-12-01

This report offers conceptual and analytical frameworks and application examples to address the question: how can broader statewide (or national) objectives be achieved while formally taking into consideration different regional priorities and constr...

Informed consent in the context of pharmacogenomic research: ethical considerations.

PubMed

Howard, H C; Joly, Y; Avard, D; Laplante, N; Phillips, M; Tardif, J C

2011-06-01

Although the scientific research surrounding pharmacogenomics (PGx) has been relatively plentiful, the ethical research concerning this discipline has developed rather conservatively. Following investigation of the ethical, legal and social issues (ELSI) of PGx research, as well as consulting with key stakeholders, we identified six outstanding ethical issues raised by the informed consent process in PGx research: (1) scope of consent; (2) consent to 'add-on' studies; (3) protection of personal information; (4) commercialization; (5) data sharing; and (6) potential risks stemming from population-based research. In discussing these six areas as well as offering specific considerations, this article offers a solid base from which future practical guidelines for informed consent in PGx research can be constructed. As such, this effort works toward filling the ELSI gap and provides ethical support to the numerous PGx projects undertaken by researchers every year.

Considerations for the effects of military deployment on children and families.

PubMed

Lincoln, Alan J; Sweeten, Kathie

2011-01-01

Children of deployed military personnel represent a unique subculture in the United States. While many children exhibit high levels of resiliency, others will struggle with the impact of a parent who has gone to war. This article looks at some of the stressors of deployment as experienced by children and offers three case examples as well as clinical considerations for those who work with the children and families of the deployed.

Bacterial bloodstream infections in the allogeneic hematopoietic cell transplant patient: new considerations for a persistent nemesis.

PubMed

Dandoy, C E; Ardura, M I; Papanicolaou, G A; Auletta, J J

2017-08-01

Bacterial bloodstream infections (BSI) cause significant transplant-related morbidity and mortality following allogeneic hematopoietic cell transplantation (allo-HCT). This manuscript reviews the risk factors for and the bacterial pathogens causing BSIs in allo-HCT recipients in the contemporary transplant period. In addition, it offers insight into emerging resistant pathogens and reviews clinical management considerations to treat and strategies to prevent BSIs in allo-HCT patients.

Radiance limits of ceramic phosphors under high excitation fluxes

NASA Astrophysics Data System (ADS)

Lenef, Alan; Kelso, John; Zheng, Yi; Tchoul, Maxim

2013-09-01

Ceramic phosphors, excited by high radiance pump sources, offer considerable potential for high radiance conversion. Interestingly, thermodynamic arguments suggest that the radiance of the luminescent spot can even exceed that of the incoming light source. In practice, however, thermal quenching and (non-thermal) optical saturation limit the maximum attainable radiance of the luminescent source. We present experimental data for Ce:YAG and Ce:GdYAG ceramics in which these limits have been investigated. High excitation fluxes are achieved using laser pumping. Optical pumping intensities exceeding 100W/mm2 have been shown to produce only modest efficiency depreciation at low overall pump powers because of the short Ce3+ lifetime, although additional limitations exist. When pump powers are higher, heat-transfer bottlenecks within the ceramic and heat-sink interfaces limit maximum pump intensities. We find that surface temperatures of these laser-pumped ceramics can reach well over 150°C, causing thermal-quenching losses. We also find that in some cases, the loss of quantum efficiency with increasing temperature can cause a thermal run-away effect, resulting in a rapid loss in converted light, possibly over-heating the sample or surrounding structures. While one can still obtain radiances on the order of many W/mm2/sr, temperature quenching effects ultimately limit converted light radiance. Finally, we use the diffusion-approximation radiation transport models and rate equation models to simulate some of these nonlinear optical pumping and heating effects in high-scattering ceramics.

Integration of microalgae cultivation with industrial waste remediation for biofuel and bioenergy production: opportunities and limitations.

PubMed

McGinn, Patrick J; Dickinson, Kathryn E; Bhatti, Shabana; Frigon, Jean-Claude; Guiot, Serge R; O'Leary, Stephen J B

2011-09-01

There is currently a renewed interest in developing microalgae as a source of renewable energy and fuel. Microalgae hold great potential as a source of biomass for the production of energy and fungible liquid transportation fuels. However, the technologies required for large-scale cultivation, processing, and conversion of microalgal biomass to energy products are underdeveloped. Microalgae offer several advantages over traditional 'first-generation' biofuels crops like corn: these include superior biomass productivity, the ability to grow on poor-quality land unsuitable for agriculture, and the potential for sustainable growth by extracting macro- and micronutrients from wastewater and industrial flue-stack emissions. Integrating microalgal cultivation with municipal wastewater treatment and industrial CO(2) emissions from coal-fired power plants is a potential strategy to produce large quantities of biomass, and represents an opportunity to develop, test, and optimize the necessary technologies to make microalgal biofuels more cost-effective and efficient. However, many constraints on the eventual deployment of this technology must be taken into consideration and mitigating strategies developed before large scale microalgal cultivation can become a reality. As a strategy for CO(2) biomitigation from industrial point source emitters, microalgal cultivation can be limited by the availability of land, light, and other nutrients like N and P. Effective removal of N and P from municipal wastewater is limited by the processing capacity of available microalgal cultivation systems. Strategies to mitigate against the constraints are discussed.

Safety and security of radioactive sources in industrial radiography in Bangladesh

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mollah, A. S.; Nazrul, M. Abdullah

2013-07-01

Malicious use of radioactive sources can involve dispersal of that material through an explosive device. There has been recognition of the threat posed by the potential malicious misuse of NDT radioactive source by terrorists. The dispersal of radioactive material using conventional explosives, referred to as a 'dirty bomb', could create considerable panic, disruption and area access denial in an urban environment. However, as it is still a relatively new topic among regulators, users, and transport and storage operators worldwide, international assistance and cooperation in developing the necessary regulatory and security infrastructure is required. The most important action in reducing themore » risk of radiological terrorism is to increase the security of radioactive sources. This paper presents safety and security considerations for the transport and site storage of the industrial radiography sources as per national regulations entitled 'Nuclear Safety and Radiation Control Rules-1997'.The main emphasis was put on the stages of some safety and security actions in order to prevent theft, sabotage or other malicious acts during the transport of the packages. As a conclusion it must be mentioned that both safety and security considerations are very important aspects that must be taking in account for the transport and site storage of radioactive sources used in the practice of industrial radiography. (authors)« less

Sub-Saharan Africa: beyond the health worker migration crisis?

PubMed

Connell, John; Zurn, Pascal; Stilwell, Barbara; Awases, Magda; Braichet, Jean-Marc

2007-05-01

Migration of skilled health workers from sub-Saharan African countries has significantly increased in this century, with most countries becoming sources of migrants. Despite the growing problem of health worker migration for the effective functioning of health care systems there is a remarkable paucity and incompleteness of data. Hence, it is difficult to determine the real extent of migration from, and within, Africa, and thus develop effective forecasting or remedial policies. This global overview and the most comprehensive data indicate that the key destinations remain the USA and the UK, and that major sources are South Africa and Nigeria, but in both contexts there is now greater diversity. Migrants move primarily for economic reasons, and increasingly choose health careers because they offer migration prospects. Migration has been at considerable economic cost, it has depleted workforces, diminished the effectiveness of health care delivery and reduced the morale of the remaining workforce. Countries have sought to implement national policies to manage migration, mitigate its harmful impacts and strengthen African health care systems. Recipient countries have been reluctant to establish effective ethical codes of recruitment practice, or other forms of compensation or technology transfer, hence migration is likely to increase further in the future, diminishing the possibility of achieving the United Nations millennium development goals and exacerbating existing inequalities in access to adequate health care.

Peer teaching and information retrieval: the role of the NICE Evidence search student champion scheme in enhancing students' confidence.

PubMed

Sbaffi, Laura; Hallsworth, Elaine; Weist, Anne

2018-03-01

This research reports on the NICE Evidence search (ES) student champion scheme (SCS) first five years of activity (2011-2016) in terms of its impact on health care undergraduate students' information search skills and search confidence. A review of students' evaluation of the scheme was carried out to chart the changes in attitude towards NICE Evidence search as an online health care information source and to monitor students' approach to information seeking. This study is based on the results of questionnaires distributed to students before and after attending a training session on NICE Evidence search delivered by their own peers. The exercise was implemented in health related universities in England over a period of five consecutive academic years. (i) Students' search confidence improved considerably after the training; (ii) ES was perceived as being an increasingly useful resource of evidence based information for their studies; (iii) the training helped students develop discerning search skills and use evidence based information sources more consistently and critically. The NICE SCS improves confidence in approaching information tasks amongst health care undergraduate students. Future developments could involve offering the training at the onset of a course of study and adopting online delivery formats to expand its geographical reach. © 2018 Health Libraries Group.

RADIATION PRESERVATION OF SELECTED FRUITS AND VEGETABLES. An Analysis of R&D Programing and Market Factors

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1961-01-01

Strawberries, peaches, citrus fruits, grapes, and tomatoes were irradiated experimentally. Results are inconclusive, but indications of both shelf-life extension and unfaqorable radiation effects were observed at dose levels below 500,000 rads. These are promising commodities for radiation sterilization in terms of value, present shelf-life, incidence and amount of spoilage, ard existing methods of preservation. The packing house is a logical location for the radiation source. Hourly capacities in the neighborhood of 10 tons per hour for the commercial facility are appropriate. Because of seasonal and geographical spread of harvesting, facilities adaptable to several crops and portable facilities deserve consideration. Preliminarymore » results are presented from studies on the wholesomeness of irradiated foods, but more work will be required for grapes, strawberries, and tomatoes. The radiation levels and types of radiation used for pasteurization theoretically could cre ate extremely minute amounts of radioactivity. Technical knowledge is sufficient to permit engineering work on a source of radiation for pilot-plant operation. Surface irradiation technology, so far relatively undeveloped, could offer an alternative with the possibility of lower costs. Economic feasibility cannot be determined until later because cost estimates are preliminary and the potential benefits are not adequately known. (auth)« less

Adolescent drivers: a developmental perspective on risk, proficiency, and safety.

PubMed

Keating, Daniel P; Halpern-Felsher, Bonnie L

2008-09-01

Despite considerable improvement in the rates of crashes, injuries, and fatalities among adolescent drivers, attributable in part to effective interventions such as graduated driver licensing, these rates and their associated health risks remain unacceptably high. To understand the sources of risky driving among teens, as well as to identify potential avenues for further advances in prevention, this article presents a review of the relevant features of contemporary research on adolescent development. Current research offers significant advances in the understanding of the sources of safe driving, proficient driving, and risky driving among adolescents. This multifaceted perspective--as opposed to simple categorization of good versus bad driving--provides new opportunities for using insights on adolescent development to enhance prevention. Drawing on recent work on adolescent physical, neural, and cognitive development, we argue for approaches to prevention that recognize both the strengths and the limitations of adolescent drivers, with particular attention to the acquisition of expertise, regulatory competence, and self-regulation in the context of perceived risk. This understanding of adolescent development spotlights the provision of appropriate and effective scaffolding, utilizing the contexts of importance to adolescents--parents, peers, and the broader culture of driving--to support safe driving and to manage the inherent risks in learning to do so.

Dietary purines in vegetarian meat analogues.

PubMed

Havlik, Jaroslav; Plachy, Vladimir; Fernandez, Javier; Rada, Vojtech

2010-11-01

The meat alternatives market offers a wide range of products resembling meat in taste, flavour or texture but based on vegetable protein sources. These high protein-low purine foods may find application in a low purine or purine-free diet, which is sometimes suggested for subjects with increased serum urate levels, i.e. hyperuricaemia. We determined purine content (uric acid, adenine, guanine, hypoxanthine, xanthine) in 39 commercially available meat substitutes and evaluated them in relation to their protein content. Some of the products contained a comparable sum of adenine and hypoxanthine per protein as meat. Analysis of variance showed an influence of protein source used. Mycoprotein-based products had significantly higher contents (2264 mg kg(-1)) of adenine and hypoxanthine per kg of 100% protein than soybean-based products (1648 mg kg(-1)) or mixtures consisting of soybean protein and wheat protein (1239 mg kg(-1)). Protein-rich vegetable-based meat substitutes might be generally accepted as meat alternatives for individuals on special diets. The type of protein used to manufacture these products determines the total content of purines, which is relatively higher in the case of mycoprotein or soybean protein, while appearing lower in wheat protein and egg white-based products. These are therefore more suitable for dietary considerations in a low-purine diet for hyperuricaemic subjects. 2010 Society of Chemical Industry

Production of High-Value Nanoparticles via Biogenic Processes Using Aquacultural and Horticultural Food Waste

PubMed Central

Ghosh, Purabi R.; Fawcett, Derek; Sharma, Shashi B.; Poinern, Gerrard E. J.

2017-01-01

The quantities of organic waste produced globally by aquacultural and horticulture are extremely large and offer an attractive renewable source of biomolecules and bioactive compounds. The availability of such large and diverse sources of waste materials creates a unique opportunity to develop new recycling and food waste utilisation strategies. The aim of this review is to report the current status of research in the emerging field of producing high-value nanoparticles from food waste. Eco-friendly biogenic processes are quite rapid, and are usually carried out at normal room temperature and pressure. These alternative clean technologies do not rely on the use of the toxic chemicals and solvents commonly associated with traditional nanoparticle manufacturing processes. The relatively small number of research articles in the field have been surveyed and evaluated. Among the diversity of waste types, promising candidates and their ability to produce various high-value nanoparticles are discussed. Experimental parameters, nanoparticle characteristics and potential applications for nanoparticles in pharmaceuticals and biomedical applications are discussed. In spite of the advantages, there are a number of challenges, including nanoparticle reproducibility and understanding the formation mechanisms between different food waste products. Thus, there is considerable scope and opportunity for further research in this emerging field. PMID:28773212

Discovery of Antimalarial Drugs from Streptomycetes Metabolites Using a Metabolomic Approach

PubMed Central

Baba, Mohd Shukri

2017-01-01

Natural products continue to play an important role as a source of biologically active substances for the development of new drug. Streptomyces, Gram-positive bacteria which are widely distributed in nature, are one of the most popular sources of natural antibiotics. Recently, by using a bioassay-guided fractionation, an antimalarial compound, Gancidin-W, has been discovered from these bacteria. However, this classical method in identifying potentially novel bioactive compounds from the natural products requires considerable effort and is a time-consuming process. Metabolomics is an emerging “omics” technology in systems biology study which integrated in process of discovering drug from natural products. Metabolomics approach in finding novel therapeutics agent for malaria offers dereplication step in screening phase to shorten the process. The highly sensitive instruments, such as Liquid Chromatography-Mass Spectrophotometry (LC-MS), Gas Chromatography-Mass Spectrophotometry (GC-MS), and Nuclear Magnetic Resonance (1H-NMR) spectroscopy, provide a wide range of information in the identification of potentially bioactive compounds. The current paper reviews concepts of metabolomics and its application in drug discovery of malaria treatment as well as assessing the antimalarial activity from natural products. Metabolomics approach in malaria drug discovery is still new and needs to be initiated, especially for drug research in Malaysia. PMID:29123551

Macroscopic modeling for heat and water vapor transfer in dry snow by homogenization.

PubMed

Calonne, Neige; Geindreau, Christian; Flin, Frédéric

2014-11-26

Dry snow metamorphism, involved in several topics related to cryospheric sciences, is mainly linked to heat and water vapor transfers through snow including sublimation and deposition at the ice-pore interface. In this paper, the macroscopic equivalent modeling of heat and water vapor transfers through a snow layer was derived from the physics at the pore scale using the homogenization of multiple scale expansions. The microscopic phenomena under consideration are heat conduction, vapor diffusion, sublimation, and deposition. The obtained macroscopic equivalent model is described by two coupled transient diffusion equations including a source term arising from phase change at the pore scale. By dimensional analysis, it was shown that the influence of such source terms on the overall transfers can generally not be neglected, except typically under small temperature gradients. The precision and the robustness of the proposed macroscopic modeling were illustrated through 2D numerical simulations. Finally, the effective vapor diffusion tensor arising in the macroscopic modeling was computed on 3D images of snow. The self-consistent formula offers a good estimate of the effective diffusion coefficient with respect to the snow density, within an average relative error of 10%. Our results confirm recent work that the effective vapor diffusion is not enhanced in snow.

Eyjafjallajokull Volcano Plume Particle-Type Characterization from Space-Based Multi-angle Imaging

NASA Technical Reports Server (NTRS)

Kahn, Ralph A.; Limbacher, James

2012-01-01

The Multi-angle Imaging SpectroRadiometer (MISR) Research Aerosol algorithm makes it possible to study individual aerosol plumes in considerable detail. From the MISR data for two optically thick, near-source plumes from the spring 2010 eruption of the Eyjafjallaj kull volcano, we map aerosol optical depth (AOD) gradients and changing aerosol particle types with this algorithm; several days downwind, we identify the occurrence of volcanic ash particles and retrieve AOD, demonstrating the extent and the limits of ash detection and mapping capability with the multi-angle, multi-spectral imaging data. Retrieved volcanic plume AOD and particle microphysical properties are distinct from background values near-source, as well as for overwater cases several days downwind. The results also provide some indication that as they evolve, plume particles brighten, and average particle size decreases. Such detailed mapping offers context for suborbital plume observations having much more limited sampling. The MISR Standard aerosol product identified similar trends in plume properties as the Research algorithm, though with much smaller differences compared to background, and it does not resolve plume structure. Better optical analogs of non-spherical volcanic ash, and coincident suborbital data to validate the satellite retrieval results, are the factors most important for further advancing the remote sensing of volcanic ash plumes from space.

The NASA space power technology program

NASA Technical Reports Server (NTRS)

Stephenson, R. Rhoads

1992-01-01

NASA has a broad technology program in the field of space power. This paper describes that program, including the roles and responsibilities of the various NASA field centers and major contractors. In the power source area, the paper discusses the SP-100 Space Nuclear Power Project, which has been under way for about seven years and is making substantial progress toward development of components for a 100-kilowatt power system that can be scaled to other sizes. This system is a candidate power source for nuclear electric propulsion, as well as for a power plant for a lunar base. In the energy storage area, the paper describes NASA's battery- and fuel-cell development programs. NASA is actively working on NiCd, NiH2, and lithium batteries. A status update is also given on a U.S. Air Force-sponsored program to develop a large (150 ampere-hour) lithium-thionyl chloride battery for the Centaur upper-stage launch vehicle. Finally, the area of power management and distribution (PMAD) is addressed, including power system components such as solid-state switches and power integrated circuits. Automated load management and other computer-controlled functions offer considerable payoffs. The state of the art in space power is described, along with NASA's medium- and long-term goals in the area.

The potential for modification in cloning and vitrification technology to enhance genetic progress in beef cattle in Northern Australia.

PubMed

Taylor-Robinson, Andrew W; Walton, Simon; Swain, David L; Walsh, Kerry B; Vajta, Gábor

2014-08-01

Recent advances in embryology and related research offer considerable possibilities to accelerate genetic improvement in cattle breeding. Such progress includes optimization and standardization of laboratory embryo production (in vitro fertilization - IVF), introduction of a highly efficient method for cryopreservation (vitrification), and dramatic improvement in the efficiency of somatic cell nuclear transfer (cloning) in terms of required effort, cost, and overall outcome. Handmade cloning (HMC), a simplified version of somatic cell nuclear transfer, offers the potential for relatively easy and low-cost production of clones. A potentially modified method of vitrification used at a centrally located laboratory facility could result in cloned offspring that are economically competitive with elite animals produced by more traditional means. Apart from routine legal and intellectual property issues, the main obstacle that hampers rapid uptake of these technologies by the beef cattle industry is a lack of confidence from scientific and commercial sources. Once stakeholder support is increased, the combined application of these methods makes a rapid advance toward desirable traits (rapid growth, high-quality beef, optimized reproductive performance) a realistic goal. The potential impact of these technologies on genetic advancement in beef cattle herds in which improvement of stock is sought, such as in northern Australia, is hard to overestimate. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

Hiawatha National Forest Riparian Inventory: A Case Study

NASA Astrophysics Data System (ADS)

Abood, S. A.

2014-12-01

Riparian areas are dynamic, transitional ecotones between aquatic and terrestrial ecosystems with well-defined vegetation and soil characteristics. Riparian areas offers wildlife habitat and stream water quality, offers bank stability and protects against erosions, provides aesthetics and recreational value, and other numerous valuable ecosystem functions. Quantifying and delineating riparian areas is an essential step in riparian monitoring, riparian management/planning and policy decisions, and in preserving its valuable ecological functions. Previous approaches to riparian areas mapping have primarily utilized fixed width buffers. However, these methodologies only take the watercourse into consideration and ignore critical geomorphology, associated vegetation and soil characteristics. Other approaches utilize remote sensing technologies such as aerial photos interpretation or satellite imagery riparian vegetation classification. Such techniques requires expert knowledge, high spatial resolution data, and expensive when mapping riparian areas on a landscape scale. The goal of this study is to develop a cost effective robust workflow to consistently map the geographic extent and composition of riparian areas within the Hiawatha National Forest boundary utilizing the Riparian Buffer Delineation Model (RBDM) v3.0 and open source geospatial data. This approach recognizes the dynamic and transitional natures of riparian areas by accounting for hydrologic, geomorphic and vegetation data as inputs into the delineation process and the results would suggests incorporating functional variable width riparian mapping within watershed management planning to improve protection and restoration of valuable riparian functionality and biodiversity.

Traceability of biotech-derived animals: application of DNA technology.

PubMed

Loftus, R

2005-04-01

Traceability is increasingly becoming standard across the agri-food industry, largely driven by recent food crises and the consequent demands for transparency within the food chain. This is leading to the development of a range of traceability concepts and technologies adapted to different industry needs. Experience with genetically modified plants has shown that traceability can play a role in increasing public confidence in biotechnology, and might similarly help allay concerns relating to the development of animal biotechnology. Traceability also forms an essential component of any risk management strategy and is a key requirement for post-marketing surveillance. Given the diversity of traceability concepts and technologies available, consideration needs to be given to the scope and precision of traceability systems for animal biotechnology. Experience to date has shown that conventional tagging and labelling systems can incorporate levels of error and may not have sufficient precision for biotech-derived animals. Deoxyribonucleic acid (DNA) technology can overcome these difficulties by tracing animals and animal by-products through their DNA code rather than an associated label. This offers the possibility of tracing some by-products of animal biotechnology through the supply chain back to source animals, offering unprecedented levels of traceability. Developments in both DNA sampling and analysis technology are making large-scale applications of DNA traceability increasingly cost effective and feasible, and are likely to lead to a broader uptake of DNA traceability concepts.

LSPV+7, a branch-point-tolerant reconstructor for strong turbulence adaptive optics.

PubMed

Steinbock, Michael J; Hyde, Milo W; Schmidt, Jason D

2014-06-20

Optical wave propagation through long paths of extended turbulence presents unique challenges to adaptive optics (AO) systems. As scintillation and branch points develop in the beacon phase, challenges arise in accurately unwrapping the received wavefront and optimizing the reconstructed phase with respect to branch cut placement on a continuous facesheet deformable mirror. Several applications are currently restricted by these capability limits: laser communication, laser weapons, remote sensing, and ground-based astronomy. This paper presents a set of temporally evolving AO simulations comparing traditional least-squares reconstruction techniques to a complex-exponential reconstructor and several other reconstructors derived from the postprocessing congruence operation. The reconstructors' behavior in closed-loop operation is compared and discussed, providing several insights into the fundamental strengths and limitations of each reconstructor type. This research utilizes a self-referencing interferometer (SRI) as the high-order wavefront sensor, driving a traditional linear control law in conjunction with a cooperative point source beacon. The SRI model includes practical optical considerations and frame-by-frame fiber coupling effects to allow for realistic noise modeling. The "LSPV+7" reconstructor is shown to offer the best performance in terms of Strehl ratio and correction stability-outperforming the traditional least-squares reconstructed system by an average of 120% in the studied scenarios. Utilizing a continuous facesheet deformable mirror, these reconstructors offer significant AO performance improvements in strong turbulence applications without the need for segmented deformable mirrors.

Isolating and Examining Sources of Suppression and Multicollinearity in Multiple Linear Regression.

PubMed

Beckstead, Jason W

2012-03-30

The presence of suppression (and multicollinearity) in multiple regression analysis complicates interpretation of predictor-criterion relationships. The mathematical conditions that produce suppression in regression analysis have received considerable attention in the methodological literature but until now nothing in the way of an analytic strategy to isolate, examine, and remove suppression effects has been offered. In this article such an approach, rooted in confirmatory factor analysis theory and employing matrix algebra, is developed. Suppression is viewed as the result of criterion-irrelevant variance operating among predictors. Decomposition of predictor variables into criterion-relevant and criterion-irrelevant components using structural equation modeling permits derivation of regression weights with the effects of criterion-irrelevant variance omitted. Three examples with data from applied research are used to illustrate the approach: the first assesses child and parent characteristics to explain why some parents of children with obsessive-compulsive disorder accommodate their child's compulsions more so than do others, the second examines various dimensions of personal health to explain individual differences in global quality of life among patients following heart surgery, and the third deals with quantifying the relative importance of various aptitudes for explaining academic performance in a sample of nursing students. The approach is offered as an analytic tool for investigators interested in understanding predictor-criterion relationships when complex patterns of intercorrelation among predictors are present and is shown to augment dominance analysis.

Feminism and psychology: critiques of methods and epistemology.

PubMed

Eagly, Alice H; Riger, Stephanie

2014-10-01

Starting in the 1960s, many of the critiques of psychological science offered by feminist psychologists focused on its methods and epistemology. This article evaluates the current state of psychological science in relation to this feminist critique. The analysis relies on sources that include the PsycINFO database, the Publication Manual of the American Psychological Association (American Psychological Association, 2010), and popular psychology methods textbooks. After situating the feminist critique within the late-20th-century shift of science from positivism to postpositivism, the inquiry examines feminists' claims of androcentric bias in (a) the underrepresentation of women as researchers and research participants and (b) researchers' practices in comparing women and men and describing their research findings. In most of these matters, psychology manifests considerable change in directions advocated by feminists. However, change is less apparent in relation to some feminists' criticisms of psychology's reliance on laboratory experimentation and quantitative methods. In fact, the analyses documented the rarity in high-citation journals of qualitative research that does not include quantification. Finally, the analysis frames feminist methodological critiques by a consideration of feminist epistemologies that challenge psychology's dominant postpositivism. Scrutiny of methods textbooks and journal content suggests that within psychological science, especially as practiced in the United States, these alternative epistemologies have not yet gained substantial influence. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

An analysis of Australian graduate critical care nurse education.

PubMed

Gill, Fenella J; Leslie, Gavin D; Grech, Carol; Latour, Jos M

2015-01-01

Preparation of specialist critical care nurses in Australia is at graduate level, although there remains considerable variation in courses offered in relation to qualification, content, assessment and outcomes. As higher education providers must now comply with the Australian Qualifications Framework (AQF) a study was conducted to examine existing critical care courses and graduate practice outcomes. Twenty-two critical care courses were reviewed. Data sources included course provider, websites, course curricula and telephone interviews with course coordinators. A framework approach, was used consisting of five key stages: preliminary immersion of raw data, conceptualising a thematic framework, indexing, charting, mapping and interpretation of data. Analysis revealed considerable variations in course delivery and graduate practice outcomes. Most courses used professional competency standards as a framework for course curricula and clinical assessment, with inconsistency in their translation to graduate practice outcomes. Twenty-one courses included clinical assessment at graduate certificate level with no clinical assessment conducted at master level. The expected practice outcome for fifteen courses was safe practice with graduates not expected to practice at a specialist or team leadership level. Minimum graduate practice standards were not included in three courses as an expected outcome. The AQF requires graduate nurse education to be compliant with academic outcome standards. The findings of our study indicate variations between courses and subsequent graduate practice outcomes. It is therefore timely to establish national critical care education graduate practice standards.

Assessment of a Hospital Palliative Care Unit (HPCU) for Cancer Patients; A Conceptual Framework.

PubMed

Rouhollahi, Mohammad Reza; Saghafinia, Masoud; Zandehdel, Kazem; Motlagh, Ali Ghanbari; Kazemian, Ali; Mohagheghi, Mohammad Ali; Tahmasebi, Mamak

2015-01-01

The first hospital palliative care unit (HPCU) in Iran (FARS-HPCU) has been established in 2008 in the Cancer Institute, which is the largest referral cancer center in the country. We attempted to assess the performance of the HPCU based on a comprehensive conceptual framework. The main aim of this study was to develop a conceptual framework for assessment of the HPCU performances through designing a value chain in line with the goals and the main processes (core and support). We collected data from a variety of sources, including international guidelines, international best practices, and expert opinions in the country and compared them with national policies and priorities. We also took into consideration the trend of the HPCU development in the Cancer Institute of Iran. Through benchmarking the gap area with the performance standards, some recommendations for better outcome are proposed. The framework for performance assessment consisted of 154 process indicators (PIs), based on which the main stakeholders of the HPCU (including staff, patients, and families) offered their scoring. The outcome revealed the state of the processes as well as the gaps. Despite a significant improvement in many processes and indicators, more development in the comprehensive and integrative aspects of FARS-HPCU performance is required. Consideration of all supportive and palliative requirements of the patients through interdisciplinary and collaborative approaches is recommended.

Rapid on-site sensing aflatoxin B1 in food and feed via a chromatographic time-resolved fluoroimmunoassay.

PubMed

Zhang, Zhaowei; Tang, Xiaoqian; Wang, Du; Zhang, Qi; Li, Peiwu; Ding, Xiaoxia

2015-01-01

Aflatoxin B1 poses grave threats to food and feed safety due to its strong carcinogenesis and toxicity, thus requiring ultrasensitive rapid on-site determination. Herein, a portable immunosensor based on chromatographic time-resolved fluoroimmunoassay was developed for sensitive and on-site determination of aflatoxin B1 in food and feed samples. Chromatographic time-resolved fluoroimmunoassay offered a magnified positive signal and low signal-to-noise ratio in time-resolved mode due to the absence of noise interference caused by excitation light sources. Compared with the immunosensing performance in previous studies, this platform demonstrated a wider dynamic range of 0.2-60 μg/kg, lower limit of detection from 0.06 to 0.12 µg/kg, and considerable recovery from 80.5% to 116.7% for different food and feed sample matrices. It was found to be little cross-reactivity with other aflatoxins (B2, G1, G2, and M1). In the case of determination of aflatoxin B1 in peanuts, corn, soy sauce, vegetable oil, and mouse feed, excellent agreement was found when compared with aflatoxin B1 determination via the conversational high-performance liquid chromatography method. The chromatographic time-resolved fluoroimmunoassay affords a powerful alternative for rapid on-site determination of aflatoxin B1 and holds a promise for food safety in consideration of practical food safety and environmental monitoring.

Rapid On-Site Sensing Aflatoxin B1 in Food and Feed via a Chromatographic Time-Resolved Fluoroimmunoassay

PubMed Central

Wang, Du; Zhang, Qi; Li, Peiwu; Ding, Xiaoxia

2015-01-01

Aflatoxin B1 poses grave threats to food and feed safety due to its strong carcinogenesis and toxicity, thus requiring ultrasensitive rapid on-site determination. Herein, a portable immunosensor based on chromatographic time-resolved fluoroimmunoassay was developed for sensitive and on-site determination of aflatoxin B1 in food and feed samples. Chromatographic time-resolved fluoroimmunoassay offered a magnified positive signal and low signal-to-noise ratio in time-resolved mode due to the absence of noise interference caused by excitation light sources. Compared with the immunosensing performance in previous studies, this platform demonstrated a wider dynamic range of 0.2-60 μg/kg, lower limit of detection from 0.06 to 0.12 µg/kg, and considerable recovery from 80.5% to 116.7% for different food and feed sample matrices. It was found to be little cross-reactivity with other aflatoxins (B2, G1, G2, and M1). In the case of determination of aflatoxin B1 in peanuts, corn, soy sauce, vegetable oil, and mouse feed, excellent agreement was found when compared with aflatoxin B1 determination via the conversational high-performance liquid chromatography method. The chromatographic time-resolved fluoroimmunoassay affords a powerful alternative for rapid on-site determination of aflatoxin B1 and holds a promise for food safety in consideration of practical food safety and environmental monitoring. PMID:25874803

Line pilot perspectives on complexity of terminal instrument flight procedures

DOT National Transportation Integrated Search

2017-07-25

Instrument flight procedures (IFPs) based on RNAV and RNP offer safety enhancements along with new levels of flexibility to negotiate terrain, airspace, and environmental considerations. However, operational implementation of performance-based IFPs d...

29 CFR 101.9 - Settlement after issuance of complaint.

Code of Federal Regulations, 2010 CFR

2010-07-01

... consideration of facts, argument, offers of settlement, or proposals of adjustment, except where time, the... the type described in § 101.7 is appropriate. Such agreement is not subject to approval by the Board...

A risk assessment methodology for critical transportation infrastructure.

DOT National Transportation Integrated Search

2002-01-01

Infrastructure protection typifies a problem of risk assessment and management in a large-scale system. This study offers a methodological framework to identify, prioritize, assess, and manage risks. It includes the following major considerations: (1...

Rail capacity improvement study for heavy rail transit operations.

DOT National Transportation Integrated Search

2012-10-01

This study offers a combination of considerations and evaluation tools pertaining to relevant means of capacity improvements (technology, operations, route, and vehicle upgrades), both conventional and emerging. Guidance regarding the economics is of...

Applying OD to the Public Sector

ERIC Educational Resources Information Center

Warrick, D. D.

1976-01-01

Discusses special considerations affecting organizational development (OD) programs in public-sector organizations, presents guidelines for using OD procedures in the public sector, and offers conclusions about the applicability of OD in the public sector. (Author/JG)

Changes of flood risk on the northern foothills of the Tatra Mountains

NASA Astrophysics Data System (ADS)

Kundzewicz, Z. W.; Stoffel, M.; Wyżga, B.; Ruiz-Villanueva, V.; Niedźwiedź, T.; Kaczka, R.; Ballesteros-Cánovas, J. A.; Pińskwar, I.; Łupikasza, E.; Zawiejska, J.; Mikuś, P.; Choryński, A.; Hajdukiewicz, H.; Spyt, B.; Janecka, K.

2017-08-01

The present paper reviews selected outcomes of the FLORIST project devoted to flood risk in the region of the northern foothills of the Tatra Mountains in Poland and summarizes novel results. The project encompassed theoretical, field, and modeling work. It was focused around observation-based hydroclimatology; projections for the future; dendrogeomorphology; as well as influence of transport of large wood on fluvial processes. The project improved understanding and interpreting changes in high-flow frequency and magnitude as well as changes in flood risk in the region, related to the presence of large wood in mountain streams. A unique database on past episodes of intense precipitation and flooding was created, harnessing multiple sources. The project showed that the analysis of tree rings and wood logs can offer useful information, complementing and considerably enriching the knowledge of river floods in the region of northern foothills of the Tatra Mountains. Retrospective and scenario-defined modeling of selected past fluvial events in the region was also performed.

Science and technology objective (STO) to develop tests for detecting microbial and chemical contaminants in food and water

NASA Astrophysics Data System (ADS)

Knechtges, Paul L.; Gargan, Thomas P., II; Burrows, William D.

2002-02-01

The assurance of safe food and water is paramount to the health and performance of the warfighter. Any technology to assess the chemical and microbial purity of food and water under field conditions must meet rigorous criteria: it must be readily portable, provide timely results (no more than 4 hours), have adequate sensitivity (1 cfu/100 mL for potable water), be compatible with military power sources, and be of complexity appropriate for operation by a Preventive Medicine Specialist. The nomination of an Army Science and Technology Objective (STO) leads to assessment of existing technologies and commercial products; identification of users, regulators and developers; definition of essential capabilities; and consideration of potential obstructions. The U.S. Army Center for Environmental Health Research has identified a number of technologies for detecting microbial contaminants in food and water and has pursued development of the more promising examples. This paper examines developmental risks in the context of the STO and offers some insight and strategies to manage them.

On recontamination and directional-bias problems in Monte Carlo simulation of PDF turbulence models. [probability density function

NASA Technical Reports Server (NTRS)

Hsu, Andrew T.

1992-01-01

Turbulent combustion can not be simulated adequately by conventional moment closure turbulent models. The probability density function (PDF) method offers an attractive alternative: in a PDF model, the chemical source terms are closed and do not require additional models. Because the number of computational operations grows only linearly in the Monte Carlo scheme, it is chosen over finite differencing schemes. A grid dependent Monte Carlo scheme following J.Y. Chen and W. Kollmann has been studied in the present work. It was found that in order to conserve the mass fractions absolutely, one needs to add further restrictions to the scheme, namely alpha(sub j) + gamma(sub j) = alpha(sub j - 1) + gamma(sub j + 1). A new algorithm was devised that satisfied this restriction in the case of pure diffusion or uniform flow problems. Using examples, it is shown that absolute conservation can be achieved. Although for non-uniform flows absolute conservation seems impossible, the present scheme has reduced the error considerably.

Energy saving through LED in signaling functions for automotive exterior lighting

NASA Astrophysics Data System (ADS)

Bony, Alexis; Hamami, Khaled; Tebbe, Frank; Mertens, Jens

2011-05-01

Safety considerations have always driven the way for improving exterior automotive lighting legal requirements. With the recent adoption of day-time running lamps for passenger cars, the steadily increasing need for reduction of vehicle power consumption has led to the introduction of LED-based day-time running lamps. Solutions with incandescent bulbs have also been implemented, as they present price advantages while offering limited design perspectives. In the meantime, technology developments has turned LED sources into ideal candidates for daytime running lamps by increasing their lumen per watt efficiency ratio towards values around 100 lm/W or higher. In this work, taking as an example the new Mercedes-Benz roadster SLK (R172), we present the first single LED daytime- running lamp, with a total power consumption below 5W per vehicle. After reviewing legal requirements, the optical and electronic concepts are discussed. Details on the tail lamp LED functions are also discussed, and particularly the advantages from the realization of fog lamp with LEDs.

The financial and economic feasibility of rural household biodigesters for poor communities in South Africa.

PubMed

Smith, Michael T; Goebel, Jessica Schroenn; Blignaut, James N

2014-02-01

Given the persistence of systemic poverty in, most notably, the rural parts of South Africa, the question is whether the use of biodigesters as a source of energy offers potential solutions to some of the difficulties and development needs faced by people in these areas. At the core, this translates into whether this technology would be financially and economically feasible for installation and use by rural households. Here we conduct both a financial and an economic cost-benefit analysis in one such community based on survey data from 120 households. Analysis of these data and supporting literature reveals that a biodigester is not a financially feasible investment for a rural household. Substantial economic benefits are, however, found to make a biodigester a worthwhile investment from a broader societal perspective. This is a compelling argument for further study and the consideration of government support in the light of broader economy-wide benefits. Copyright © 2013 Elsevier Ltd. All rights reserved.

Legal Preemption and the Prevention of Chronic Conditions

PubMed Central

Corbett, Alicia

2016-01-01

State and local legal innovations to address chronic conditions are an ongoing source of public health improvements. For decades, some of the most ingenious law and policy ideas to address the underlying causes of chronic conditions and their contributing factors have emerged from state or local public sector grassroots initiatives in diverse areas, including tobacco use, safe housing and transportation, and environmental hazards. These reforms, however, are susceptible to invalidation through the legal doctrine of preemption. Embedded throughout our constitutional system, preemption refers to how state or local laws may be averted, displaced, or negated by conflicting laws at a higher level of government. Preemption can be complex in concept and application, leading to considerable confusion among public health leaders seeking to generate meaningful policy proposals. The objective of this article is to unravel the legal concept of preemption, explain its use as a tool to both thwart or further public health interventions, and offer practical guidance for how to legally navigate around it to address factors underlying chronic conditions. PMID:27362933

Use of olive oil-in-water gelled emulsions in model turkey breast emulsions

NASA Astrophysics Data System (ADS)

Serdaroğlu, M.; Öztürk, B.

2017-09-01

Today, gelled emulsion systems offer a novel possibility in lipid modification of meat products. In this study, we aimed to investigate the quality characteristics of model turkey emulsions that were prepared with olive oil-in-water gelled emulsion (GE) as partial or total beef fat replacer. The results indicated that while most of the GE treatments showed equivalent emulsion characteristics in terms of emulsion stability, water-holding capacity and cook yield, utilization of 100% GE as the lipid source could increase total expressible fluid of the model turkey emulsion and thus negatively affect the quality. Utilization of GE was effective in total fat reduction, as the model turkey emulsions formulated with more than 50% GE had significantly lower fat content compared to full-beef fat control model emulsion. However, beef fat replacement with GE produced considerable changes in colour parameters. Finally, it was concluded that utilization of GE as a partial beef fat replacer has good potential to enhance stability and reduce total fat in turkey meat emulsion products.

A gender-centered ecological framework targeting Black men living with diabetes: integrating a "masculinity" perspective in diabetes management and education research.

PubMed

Jack, Leonard; Toston, Tyra; Jack, Nkenge H; Sims, Mario

2010-03-01

Blacks have traditionally experienced a disproportionate burden of diabetes in the United States. Research published from 1980 to 2008 revealed a paucity of diabetes education and management research targeting Black men. There is a paucity of published research that takes into consideration attributes of "being male," such as masculinity, and how its attributes influence diabetes self-management behaviors. This article discusses three important factors that may help explain diabetes-related disparities among Black men.These factors include absence of consistent sources of health care, lack of health insurance, and the absence of a masculinity perspective in diabetes education and management research. This article offers a gender-centered ecological framework that examines pathways between demographic factors, family functioning, knowledge and psychological health, biological health, behavioral health and medical compliance, masculinity, and diabetes-related outcomes. Recommendations for future research that consider how aspects of masculinity might lead to the identification of gender-based risk factors are presented.

Space or terrestrial energy?

NASA Astrophysics Data System (ADS)

Boulet, L.

Consideration is given to the possibility of generating sufficient energy at acceptable costs on earth to offset the need to build solar power satellite systems (SPS). Electricity usage, one of the basic driving forces of developed nations, grows with the population. Currently comprising 33 pct of the total world energy used, electricity is projected to grow to a 50-55 pct share in the 21st century. Future terrestrial electrical energy sources include carbon-based fuels, nuclear (fusion or fission), and the renewable solar technologies. Carbon-based fuel supplies can last until 2030 AD, about the same as fission plants with recycled fuel. Breeder reactors would stretch the nuclear fuels to the year 3000. Solar technologies offer more immediate solutions than fusion reactors and can produce 50 pct of the power available from the construction of the maximum number of nuclear power plants. The addition of SPS would further augment the total. Combinations of all the technologies are recommended, with local research for the most appropriate technology for each nation.

Self-propelled micromotors based on Au-mesoporous silica nanorods.

PubMed

Wang, Ying-Shuai; Xia, Hong; Lv, Chao; Wang, Lei; Dong, Wen-Fei; Feng, Jing; Sun, Hong-Bo

2015-07-28

Here, a chemical powered micromotor from the assembly of Au-SiO2 nanorods is presented. This new micromotor can be propelled efficiently by hydrogen bubbles generated from a hydrolysis reaction of aqueous NaBH4 and KBH4 and by oxygen bubbles produced by decomposition of H2O2. The monodisperse Au nanoparticles in mesoporous silica particles could catalyze the decomposition of two different kinds of fuels and produce bubbles. High speeds of 80 μm s(-1) and recycles of more than 30 times are achieved in both NaBH4 and H2O2 media. Locomotion and rolling forms of movement were found. The locomotion forms can be obtained in a larger proportion by patterning the Au-SiO2 nanorods and a PDMS membrane. These micromotors that use multiple fuel sources to power them offer a broader scope of preparation and show considerable promise for diverse applications of nanomotors in different chemical environments.

Evaluating Sustainability Models for Interoperability through Brokering Software

NASA Astrophysics Data System (ADS)

Pearlman, Jay; Benedict, Karl; Best, Mairi; Fyfe, Sue; Jacobs, Cliff; Michener, William; Nativi, Stefano; Powers, Lindsay; Turner, Andrew

2016-04-01

Sustainability of software and research support systems is an element of innovation that is not often discussed. Yet, sustainment is essential if we expect research communities to make the time investment to learn and adopt new technologies. As the Research Data Alliance (RDA) is developing new approaches to interoperability, the question of uptake and sustainability is important. Brokering software sustainability is one of the areas that is being addressed in RDA. The Business Models Team of the Research Data Alliance Brokering Governance Working Group examined several support models proposed to promote the long-term sustainability of brokering middleware. The business model analysis includes examination of funding source, implementation frameworks and challenges, and policy and legal considerations. Results of this comprehensive analysis highlight advantages and disadvantages of the various models with respect to the specific requirements for brokering services. We offer recommendations based on the outcomes of this analysis that suggest that hybrid funding models present the most likely avenue to long term sustainability.

NanoSIMS for biological applications: Current practices and analyses

DOE PAGES

Nunez, Jamie R.; Renslow, Ryan S.; Cliff, III, John B.; ...

2017-09-27

Secondary ion mass spectrometry (SIMS) has become an increasingly utilized tool in biologically-relevant studies. Of these, high lateral resolution methodologies using the NanoSIMS 50/50L have been especially powerful within many biological fields over the past decade. Here, we provide a review of this technology, sample preparation and analysis considerations, examples of recent biological studies, data analysis, and current outlooks. Specifically, we offer an overview of SIMS and development of the NanoSIMS. We describe the major experimental factors that should be considered prior to NanoSIMS analysis and then provide information on best practices for data analysis and image generation, which includesmore » an in-depth discussion of appropriate colormaps. Additionally, we provide an open-source method for data representation that allows simultaneous visualization of secondary electron and ion information within a single image. Lastly, we present a perspective on the future of this technology and where we think it will have the greatest impact in near future.« less

Knowledge and experience of young people of drug abuse 1969-84.

PubMed

Wright, J D; Pearl, L

1986-01-18

An anonymous questionnaire survey of the knowledge and experience of drug abuse among fourth year pupils in three Wolverhampton secondary schools in 1969, 1974, 1979, and 1984 showed familiarity with the names of drugs but considerable ignorance and misunderstanding about how the drugs were taken and their dangers. The proportion of pupils who knew someone taking illicit drugs almost doubled over the period from 15% in 1969 to 28% in 1984, and the proportion of those who had been offered illicit drugs almost trebled, from 5% in 1969 to 14% in 1984. Television remained the most important source of information about drugs. Peer group and social pressures continued to be the most important reason for starting to take drugs. The results of this study endorse the need for continued evaluation of programmes of education about drugs. Such programmes must be part of a wider programme of health and social education, define clear goals, and be sensitive to culture, locality, and ability.

Work, love, and death-thought accessibility: A terror management investigation.

PubMed

McCabe, Simon; Daly, Michael

2018-05-07

Terror management theory suggests that following culturally derived scripts for valued behaviour protects people from death concerns, and conversely, not meeting standards for cultural value can weaken this protection, heightening mortality concerns. Using this conceptual framework, we examine (1) how considerations of loss of employment, a source of cultural value for many, relates to the accessibility of death-related cognition, and (2) the moderating role of job market health, and (3) involvement in close relationships. Study 1 found that writing about being unemployed (vs. a control topic) led to greater mortality-related cognition. Study 2 found that considering unemployment heightened death cognition, but only when participants were led to perceive the job market as unhealthy. Finally, Study 3 found that considering unemployment led to greater death cognition, but not for those involved in a close relationship. Findings offer insight into a previously overlooked consequence of unemployment, and factors that may serve a protective function. © 2018 The British Psychological Society.

New potential phytotherapeutics obtained from white mulberry (Morus alba L.) leaves.

PubMed

Gryn-Rynko, Anna; Bazylak, Grzegorz; Olszewska-Slonina, Dorota

2016-12-01

The present work demonstrates the profound and unique phyto-pharmacological and nutritional profile of white mulberry (Morus alba L.) leaves which containing considerable amounts of easy digestive proteins, carbohydrates, micro- and macronutrients, polyphenols, free amino acids, organic acids. The wide range of significant biopharmaceutical activities of the aqueous and polar organic solvents extracts from mulberry leaves - including antidiabetic, antibacterial, anticancer, cardiovascular, hypolipidemic, antioxidant, antiatherogenic, and anti-inflammatory - have been critically discussed. The main objective was to demonstrate the results of recently published study on the components of white mulberry leaves exhibiting their biological activity in the various pathological and health human ailments. In addition, we intend to drawn the attention of researchers and public health workers for the extended exploration of this deciduous plant leaves as the source of potential indigenous nutraceuticals and functional food products to enable development of alternative prevention and treatment protocols offered in therapy of the common non-communicable diseases and malignances. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Epidemiology, Diagnosis, and Management of Clostridium difficile Infection in Patients with Inflammatory Bowel Disease

PubMed Central

Rao, Krishna; Higgins, Peter D. R.

2016-01-01

Clostridium difficile infection (CDI) is a major source of morbidity and mortality for the US healthcare system, and frequently complicates the course of inflammatory bowel disease (IBD). Patients with IBD are more likely to be colonized with C. difficile and develop active infection than the general population. They are also more likely to have severe CDI and develop subsequent complications such as IBD flare, colectomy, or death. Even after successful initial treatment and recovery, recurrent CDI is common. Management of CDI in IBD is fraught with diagnostic and therapeutic challenges, since the clinical presentations of CDI and IBD flare have considerable overlap. Fecal microbiota transplantation can be successful in curing recurrent CDI when other treatments have failed, but may also trigger IBD flare and this warrants caution. New, experimental treatments including vaccines, monoclonal antibodies, and non-toxigenic strains of C. difficile offer promise but are not yet available for clinicians. A better understanding of the complex relationship between the gut microbiota, CDI, and IBD is needed. PMID:27120571

Use of Social Media to Target Information-Driven Arms Control and Nonproliferation Verification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kreyling, Sean J.; Williams, Laura S.; Gastelum, Zoe N.

There has been considerable discussion within the national security community, including a recent workshop sponsored by the U.S. State Department, about the use of social media for extracting patterns of collective behavior and influencing public perception in areas relevant to arms control and nonproliferation. This paper seeks to explore if, and how, social media can be used to supplement nonproliferation and arms control inspection and monitoring activities on states and sites of greatest proliferation relevance. In this paper, we set the stage for how social media can be applied in this problem space and describe some of the foreseen challenges,more » including data validation, sources and attributes, verification, and security. Using information analytics and data visualization capabilities available at Pacific Northwest National Laboratory (PNNL), we provide graphical examples of some social media "signatures" of potential relevance for nonproliferation and arms control purposes. We conclude by describing a proposed case study and offering recommendations both for further research and next steps by the policy community.« less

2010 ACVIM Small Animal Consensus Statement on Leptospirosis: Diagnosis, Epidemiology, Treatment, and Prevention

PubMed Central

Sykes, JE; Hartmann, K; Lunn, KF; Moore, GE; Stoddard, RA; Goldstein, RE

2011-01-01

This report offers a consensus opinion on the diagnosis, epidemiology, treatment, and prevention of leptospirosis in dogs, an important zoonosis. Clinical signs of leptospirosis in dogs relate to development of renal disease, hepatic disease, uveitis, and pulmonary hemorrhage. Disease may follow periods of high rainfall, and can occur in dogs roaming in proximity to water sources, farm animals, or wildlife, or dogs residing in suburban environments. Diagnosis is based on acute and convalescent phase antibody titers by the microscopic agglutination test (MAT), with or without use of polymerase chain reaction assays. There is considerable interlaboratory variation in MAT results, and the MAT does not accurately predict the infecting serogroup. The recommended treatment for optimal clearance of the organism from renal tubules is doxycycline, 5 mg/kg PO q12h, for 14 days. Annual vaccination can prevent leptospirosis caused by serovars included in the vaccine and is recommended for dogs at risk of infection. PMID:21155890

Light emitting fabric technologies for photodynamic therapy.

PubMed

Mordon, Serge; Cochrane, Cédric; Tylcz, Jean Baptiste; Betrouni, Nacim; Mortier, Laurent; Koncar, Vladan

2015-03-01

Photodynamic therapy (PDT) is considered to be a promising method for treating various types of cancer. A homogeneous and reproducible illumination during clinical PDT plays a determinant role in preventing under- or over-treatment. The development of flexible light sources would considerably improve the homogeneity of light delivery. The integration of optical fiber into flexible structures could offer an interesting alternative. This paper aims to describe different methods proposed to develop Side Emitting Optical Fibers (SEOF), and how these SEOF can be integrated in a flexible structure to improve light illumination of the skin during PDT. Four main techniques can be described: (i) light blanket integrating side-glowing optical fibers, (ii) light emitting panel composed of SEOF obtained by micro-perforations of the cladding, (iii) embroidery-based light emitting fabric, and (iv) woven-based light emitting fabric. Woven-based light emitting fabrics give the best performances: higher fluence rate, best homogeneity of light delivery, good flexibility. Copyright © 2014 Elsevier B.V. All rights reserved.

The neem limonoids azadirachtin and nimbolide inhibit hamster cheek pouch carcinogenesis by modulating xenobiotic-metabolizing enzymes, DNA damage, antioxidants, invasion and angiogenesis.

PubMed

Priyadarsini, Ramamurthi Vidya; Manikandan, Palrasu; Kumar, Gurram Harish; Nagini, Siddavaram

2009-05-01

The neem tree has attracted considerable research attention as a rich source of limonoids that have potent antioxidant and anti-cancer properties. The present study was designed to evaluate the chemopreventive potential of the neem limonoids azadirachtin and nimbolide based on in vitro antioxidant assays and in vivo inhibitory effects on 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster buccal pouch (HBP) carcinogenesis. Both azadirachtin and nimbolide exhibited concentration-dependent anti-radical scavenging activity and reductive potential in the order: nimbolide > azadirachtin > ascorbate. Administration of both azadirachtin and nimbolide inhibited the development of DMBA-induced HBP carcinomas by influencing multiple mechanisms including prevention of procarcinogen activation and oxidative DNA damage, upregulation of antioxidant and carcinogen detoxification enzymes and inhibition of tumour invasion and angiogenesis. On a comparative basis, nimbolide was found to be a more potent antioxidant and chemopreventive agent and offers promise as a candidate agent in multitargeted prevention and treatment of cancer.

Patient Electronic Health Records as a Means to Approach Genetic Research in Gastroenterology.

PubMed

Ananthakrishnan, Ashwin N; Lieberman, David

2015-10-01

Electronic health records (EHRs) are being increasingly utilized and form a unique source of extensive data gathered during routine clinical care. Through use of codified and free text concepts identified using clinical informatics tools, disease labels can be assigned with a high degree of accuracy. Analysis linking such EHR-assigned disease labels to a biospecimen repository has demonstrated that genetic associations identified in prospective cohorts can be replicated with adequate statistical power and novel phenotypic associations identified. In addition, genetic discovery research can be performed utilizing clinical, laboratory, and procedure data obtained during care. Challenges with such research include the need to tackle variability in quality and quantity of EHR data and importance of maintaining patient privacy and data security. With appropriate safeguards, this novel and emerging field of research offers considerable promise and potential to further scientific research in gastroenterology efficiently, cost-effectively, and with engagement of patients and communities. Copyright © 2015 AGA Institute. Published by Elsevier Inc. All rights reserved.

NanoSIMS for biological applications: Current practices and analyses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nunez, Jamie R.; Renslow, Ryan S.; Cliff, III, John B.

Secondary ion mass spectrometry (SIMS) has become an increasingly utilized tool in biologically-relevant studies. Of these, high lateral resolution methodologies using the NanoSIMS 50/50L have been especially powerful within many biological fields over the past decade. Here, we provide a review of this technology, sample preparation and analysis considerations, examples of recent biological studies, data analysis, and current outlooks. Specifically, we offer an overview of SIMS and development of the NanoSIMS. We describe the major experimental factors that should be considered prior to NanoSIMS analysis and then provide information on best practices for data analysis and image generation, which includesmore » an in-depth discussion of appropriate colormaps. Additionally, we provide an open-source method for data representation that allows simultaneous visualization of secondary electron and ion information within a single image. Lastly, we present a perspective on the future of this technology and where we think it will have the greatest impact in near future.« less

Tunisian date (Phoenix dactylifera L.) by-products: Characterization and potential effects on sensory, textural and antioxidant properties of dairy desserts.

PubMed

Jridi, Mourad; Souissi, Nabil; Salem, Marwa Ben; Ayadi, M A; Nasri, Moncef; Azabou, Samia

2015-12-01

Three Tunisian date varieties, Deglet Nour, Kentichi and Allig, served to produce syrups and powders, which were then examined for their physico-chemical composition and antioxidant properties. Different proportions of these sweetening-like agents were incorporated to produce nine different formulations of dairy desserts, with lower amount of added sugars to avoid any artificial flavoring or coloring agents. Sensory and color evaluation data revealed that incorporating Deglet Nour and Kentichi syrup offers the most desirable formulation. Furthermore, syrup polysaccharides and fibers contribute to better maintain the final product texture. In addition, date by-products create a good source of natural thickening agents, involved in enhancing apparent viscosity and spontaneous exudation. Thanks to their high content in phenolic compounds, date by-products considerably improve antioxidant activities of the formulated desserts. Therefore, they could be valued as natural ingredients in the formulation of novel dairy products with high nutritional-properties. Copyright © 2015 Elsevier Ltd. All rights reserved.

Population research potentials in Africa.

PubMed

Hyden, G

1980-01-01

There is a need in Africa to test prevailing theories and concepts in population studies to see how they apply to this culture. Most of the prevailing perspective on population issues can be influenced by development strategies and policies affecting demographic variables. So research designed to determine the longterm consequences of rural settlement policies on subsequent access to family planning or family planning policies are also needed, as are studies which zero in on the work and results of specific population projects. The following issues are considered worth special consideration in Africa, where the vast majority of women live in rural areas where family planning services will not reach for some time. The areas of investigation which seem most pertinent in sub-saharan Africa are: side effect of contraceptive devices and agents; infertility assessments, social and medical consequences of adolescent pregnancies, the means of offering effective population education in rural African areas, the possible effects of fertility control programs on demographic transition, and potential funding sources.

Application of Preventative Legal Considerations to the Alumni Affairs Administrator.

ERIC Educational Resources Information Center

Miles, Albert S.; Miller, Michael T.

Colleges and universities increasingly rely on fund raising activities as a major source of operating revenue, a process which is wrought with legal pitfalls. This document provides an overview of the legal considerations of fund raising for the alumni and development officer, focusing particularly on span of control considerations between alumni…

Novel MixSIAR fingerprint model implementation in a Mediterranean mountain catchment

NASA Astrophysics Data System (ADS)

Lizaga, Ivan; Gaspar, Leticia; Blake, William; Palazón, Leticia; Quijano, Laura; Navas, Ana

2017-04-01

Increased sediment erosion levels can lead to degraded water and food quality, reduced aquatic biodiversity, decrease reservoir capacity and restrict recreational usage but determining soil redistribution and sediment budgets in watersheds is often challenging. One of the methods for making such determinations applies sediment fingerprinting methods by using sediment properties. The fingerprinting procedure tests a range of source material tracer properties to select a subset that can discriminate between the different potential sediment sources. The present study aims to test the feasibility of geochemical and radioisotopic fingerprint properties to apportion sediment sources within the Barués catchment. For this purpose, the new MixSIAR unmixing model was implemented as statistical tool. A total of 98 soil samples from different land cover sources (Mediterranean forest, pine forest scrubland, agricultural and subsoil) were collected in the Barués catchment (23 km2). This new approach divides the catchment into six different sub-catchments to evaluate how the sediment provenance varies along the river and the percentage of its sources and not only the contribution at the end. For this purpose, target sediments were collected at the end of each sub-catchment to introduce the variation along the entire catchment. Geochemistry and radioisotopic activity were analyzed for each sample and introduced as input parameters in the model. Percentage values from the five sources were different along the different subcatchments and the variations of all of them are summarized at the final target sample located at the end of the catchment. This work represents a good approximation to the fine sediment provenance in Mediterranean agricultural catchments and has the potential to be used for water resource control and future soil management. Identifying sediment contribution from different land uses offers considerable potential to prevent environmental degradation and the decrease in food production and quality.

Comparing Bayesian stable isotope mixing models: Which tools are best for sediments?

NASA Astrophysics Data System (ADS)

Morris, David; Macko, Stephen

2016-04-01

Bayesian stable isotope mixing models have received much attention as a means of coping with multiple sources and uncertainty in isotope ecology (e.g. Phillips et al., 2014), enabling the probabilistic determination of the contributions made by each food source to the total diet of the organism in question. We have applied these techniques to marine sediments for the first time. The sediments of the Chukchi Sea and Beaufort Sea offer an opportunity to utilize these models for organic geochemistry, as there are three likely sources of organic carbon; pelagic phytoplankton, sea ice algae and terrestrial material from rivers and coastal erosion, as well as considerable variation in the marine δ13C values. Bayesian mixing models using bulk δ13C and δ15N data from Shelf Basin Interaction samples allow for the probabilistic determination of the contributions made by each of the sources to the organic carbon budget, and can be compared with existing source contribution estimates based upon biomarker models (e.g. Belicka & Harvey, 2009, Faux, Belicka, & Rodger Harvey, 2011). The δ13C of this preserved material varied from -22.1 to -16.7‰ (mean -19.4±1.3‰), while δ15N varied from 4.1 to 7.6‰ (mean 5.7±1.1‰). Using the SIAR model, we found that water column productivity was the source of between 50 and 70% of the organic carbon buried in this portion of the western Arctic with the remainder mainly supplied by sea ice algal productivity (25-35%) and terrestrial inputs (15%). With many mixing models now available, this study will compare SIAR with MixSIAR and the new FRUITS model. Monte Carlo modeling of the mixing polygon will be used to validate the models, and hierarchical models will be utilised to glean more information from the data set.

Seeking History: Teaching with Primary Sources in Grades 4-6.

ERIC Educational Resources Information Center

Edinger, Monica

This book offers ideas about using primary sources to enhance students' understandings of history. It discusses the following resources, methods, and ideas: types of primary sources; tips on finding and preparing primary sources for student use; personal, local, and remote history activities; detailed descriptions of diverse projects; guidelines…

Common origins and the ethics of planetary seeding

NASA Astrophysics Data System (ADS)

Milligan, Tony

2016-10-01

Faced with a choice between attempting to seed another world with terrestrially-sourced microbes (with which we would have a shared origin) and microbes sourced from elsewhere within the solar system (whose origins might therefore differ), would we have any non-instrumental ethical reason to favour the terrestrial microbes? What follows will argue that in relation to the goals of promoting life similar to our own, or even simply microbial life, we might conceivably make such an appeal and do so in a defensible manner. However, in no case would such a consideration operate as a silencer for rival considerations (such as likelihood of success, enhancing diversity or historical justice). The thought experiment serves to highlight the diversity of considerations which are in play in ethical deliberation about matters of astrobiology and the role of practical wisdom rather than trumping considerations.

Hello handsome! Male's facial attractiveness gives rise to female's fairness bias in Ultimatum Game scenarios—An ERP study

PubMed Central

2017-01-01

The current study delineated how male proposers’ facial attractiveness affect female responders’ fairness considerations and their subsequent decision outcome during the Ultimatum Game (UG). Event Related Potentials (ERPs) were recorded from 17 female subjects, who played the role as responders and had to decide whether to accept offers from either attractive or unattractive male proposers. Behavioral data (Acceptance Ratio and Response time) revealed that, more offers were accepted from attractive-face conditions; subjects typically responded quicker to unfair offers from unattractive proposers as compared with slower to unfair offers from attractive proposers. The ERP data demonstrated similar N2 amplitudes elicited by both attractive and unattractive faces, and a larger early frontal LPP elicited by the attractive faces compared with unattractive ones, but no significant differences of both late posterior LPP and typical parietal LPP amplitudes were observed between these two face conditions, which was different from our previous study with similar paradigm but male participants. The results suggest that, in comparison to males, females might not experience the potential attention bias towards unattractive opposite-sex faces and are less likely to possess an enhanced processing and evaluation of those faces. This phenomenon might be explained by endogenous gender differences in mate preference. The feedback-related negativity (FRN) and P300 responses during an offer presentation were further measured in both attractive-face and unattractive-face conditions and the results demonstrated that the amplitudes elicited by fair and unfair offers were not statistically different in the former condition, but were different in the latter condition. More specifically, unfair offers generated larger FRN and smaller P300 than fair ones in the unattractive-face condition. Findings suggest that, although females tend to possess less salient evaluation of male’s facial attractiveness, the attractiveness of male proposers would still attenuate female responders’ fairness consideration during the UG. PMID:28678888

Hello handsome! Male's facial attractiveness gives rise to female's fairness bias in Ultimatum Game scenarios-An ERP study.

PubMed

Ma, Qingguo; Qian, Da; Hu, Linfeng; Wang, Lei

2017-01-01

The current study delineated how male proposers' facial attractiveness affect female responders' fairness considerations and their subsequent decision outcome during the Ultimatum Game (UG). Event Related Potentials (ERPs) were recorded from 17 female subjects, who played the role as responders and had to decide whether to accept offers from either attractive or unattractive male proposers. Behavioral data (Acceptance Ratio and Response time) revealed that, more offers were accepted from attractive-face conditions; subjects typically responded quicker to unfair offers from unattractive proposers as compared with slower to unfair offers from attractive proposers. The ERP data demonstrated similar N2 amplitudes elicited by both attractive and unattractive faces, and a larger early frontal LPP elicited by the attractive faces compared with unattractive ones, but no significant differences of both late posterior LPP and typical parietal LPP amplitudes were observed between these two face conditions, which was different from our previous study with similar paradigm but male participants. The results suggest that, in comparison to males, females might not experience the potential attention bias towards unattractive opposite-sex faces and are less likely to possess an enhanced processing and evaluation of those faces. This phenomenon might be explained by endogenous gender differences in mate preference. The feedback-related negativity (FRN) and P300 responses during an offer presentation were further measured in both attractive-face and unattractive-face conditions and the results demonstrated that the amplitudes elicited by fair and unfair offers were not statistically different in the former condition, but were different in the latter condition. More specifically, unfair offers generated larger FRN and smaller P300 than fair ones in the unattractive-face condition. Findings suggest that, although females tend to possess less salient evaluation of male's facial attractiveness, the attractiveness of male proposers would still attenuate female responders' fairness consideration during the UG.

“Will Employers Drop Health Insurance Coverage because of the Affordable Care Act?” Health Affairs 32(9): 1522–1530

PubMed Central

Buchmueller, Thomas; Carey, Colleen; Levy, Helen G.

2014-01-01

Since the passage of the Affordable Care Act, there has been considerable speculation about how many employers will stop offering health insurance once the major coverage provisions of the Act take effect. While some observers predict little aggregate effect, others believe that 2014 marks the beginning of the end for our current system of employer- sponsored insurance. We address the question “how will employer health insurance offering respond to health reform?” using theoretical and empirical evidence. First, we describe economic models of why employers offer insurance. Second, we recap the relevant provisions of health reform and use our economic framework to consider how they may affect employer offers. Third, we review the various predictions that have been made on this subject. Finally, we offer some observations on interpreting early data from 2014. PMID:24019355

Fuel Sources | Climate Neutral Research Campuses | NREL

Science.gov Websites

Fuel Sources Fuel Sources Research campuses can reduce carbon emissions and meet climate action describe how examining fuel sources may fit into your climate action plans. Considerations Sample Project are making this switch as part of their climate action plans. Another important point is the wide

Media--it takes more than flipping a switch.

PubMed

Miller, J

1980-01-01

Choosing the right audiovisual media for a health education program involves a variety of considerations, not the least of which is budget. The following article offers tips on making an informed, intelligent selection of media programs.

Alternative funding policies for the uninsured: exploring the value of hospital tax exemption.

PubMed

Kane, N M; Wubbenhorst, W H

2000-01-01

The tax exemption accorded private, nonprofit hospitals is being subjected to more scrutiny as the numbers of uninsured grow; meanwhile, charity care competes with market-driven priorities. Current public policies tie hospital tax exemption to the provision of charity care, but there is a gap in the size and distribution of values between tax exemption and the charity care that is provided. Most hospitals, in a study reported here, provided free care at a level below the value of their tax exemption, even when 50 percent of bad debt was included in the care value. However, hospitals in the poorest communities offered considerably more care than the value of their tax exemption, whereas those in wealthier communities offered considerably less. Policies at local, state, and federal levels should be designed to exert leverage on hospitals to provide free care at a level commensurate with the value of their tax exemptions.

Alternative Funding Policies for the Uninsured: Exploring the Value of Hospital Tax Exemption

PubMed Central

Kane, Nancy M.; Wubbenhorst, William H.

2000-01-01

The tax exemption accorded private, nonprofit hospitals is being subjected to more scrutiny as the numbers of uninsured grow; meanwhile, charity care competes with market-driven priorities. Current public policies tie hospital tax exemption to the provision of charity care, but there is a gap in the size and distribution of values between tax exemption and the charity care that is provided. Most hospitals, in a study reported here, provided free care at a level below the value of their tax exemption, even when 50 percent of bad debt was included in the care value. However, hospitals in the poorest communities offered considerably more care than the value of their tax exemption, whereas those in wealthier communities offered considerably less. Policies at local, state, and federal levels should be designed to exert leverage on hospitals to provide free care at a level commensurate with the value of their tax exemptions. PMID:10934992

Image restoration and superresolution as probes of small scale far-IR structure in star forming regions

NASA Technical Reports Server (NTRS)

Lester, D. F.; Harvey, P. M.; Joy, M.; Ellis, H. B., Jr.

1986-01-01

Far-infrared continuum studies from the Kuiper Airborne Observatory are described that are designed to fully exploit the small-scale spatial information that this facility can provide. This work gives the clearest picture to data on the structure of galactic and extragalactic star forming regions in the far infrared. Work is presently being done with slit scans taken simultaneously at 50 and 100 microns, yielding one-dimensional data. Scans of sources in different directions have been used to get certain information on two dimensional structure. Planned work with linear arrays will allow us to generalize our techniques to two dimensional image restoration. For faint sources, spatial information at the diffraction limit of the telescope is obtained, while for brighter sources, nonlinear deconvolution techniques have allowed us to improve over the diffraction limit by as much as a factor of four. Information on the details of the color temperature distribution is derived as well. This is made possible by the accuracy with which the instrumental point-source profile (PSP) is determined at both wavelengths. While these two PSPs are different, data at different wavelengths can be compared by proper spatial filtering. Considerable effort has been devoted to implementing deconvolution algorithms. Nonlinear deconvolution methods offer the potential of superresolution -- that is, inference of power at spatial frequencies that exceed D lambda. This potential is made possible by the implicit assumption by the algorithm of positivity of the deconvolved data, a universally justifiable constraint for photon processes. We have tested two nonlinear deconvolution algorithms on our data; the Richardson-Lucy (R-L) method and the Maximum Entropy Method (MEM). The limits of image deconvolution techniques for achieving spatial resolution are addressed.

The songs of Tlaloc: Interference of ten ceramical duct flutes, Offering 89 of the Aztec Templo Mayor

NASA Astrophysics Data System (ADS)

Both, M. A. Adje

2002-11-01

Among the many preserved sound artefacts deposited in the offerings of the Aztec Templo Mayor are a set of ten tubular duct flutes made from clay, dating Late Postclassic Mesoamerica, 1350-1521 AD. The aerophones are completely painted in blue, and characterized by: (1) a short mouthpiece; (2) a framed aperture; (3) a tube with four fingerholes; and (4) an applicated mask with features of the Aztec rain god Tlaloc, basically three rings and a standardized relief structure of two clouds. While all measurements follow the same pattern, one particular organological distinction was made, as five flutes show an exit hole in the middle ring of the mask and five flutes are stopped. Thus, five instruments sound considerably higher, apart from the minimal pitch deviation of each specimen. Both the tonal capacity of each flute and the acoustics of several flutes played simultaneously were recorded and measured. A series of remarkable interference effects could be produced, which were strongly related to the ritual complex reflected in the offering. Taking in consideration the Aztec concept of music, it could be supposed that they were perceived as a principle of the song, or proper voice of Tlaloc.

Overcoming Challenges in School-Wide Survey Administration.

PubMed

Rasberry, Catherine N; Rose, India; Kroupa, Elizabeth; Hebert, Andrew; Geller, Amanda; Morris, Elana; Lesesne, Catherine A

2018-01-01

School-based surveys provide a useful method for gathering data from youth. Existing literature offers many examples of data collection through school-based surveys, and a small subset of literature describes methodological approaches or general recommendations for health promotion professionals seeking to conduct school-based data collection. Much less is available on real-life logistical challenges (e.g., minimizing disruption in the school day) and corresponding solutions. In this article, we fill that literature gap by offering practical considerations for the administration of school-based surveys. The protocol and practical considerations outlined in the article are based on a survey conducted with 11,681 students from seven large, urban public high schools in the southeast United States. We outline our protocol for implementing a school-based survey that was conducted with all students school-wide, and we describe six types of key challenges faced in conducting the survey: consent procedures, scheduling, locating students within the schools, teacher failure to administer the survey, improper administration of the survey, and minimizing disruption. For each challenge, we offer our key lessons learned and associated recommendations for successfully implementing school-based surveys, and we provide relevant tools for practitioners planning to conduct their own surveys in schools.

Recruiting medical students to rural practice

PubMed Central

Jutzi, Leah; Vogt, Kelly; Drever, Erin; Nisker, Jeff

2009-01-01

ABSTRACT OBJECTIVE To explore the strategies used by rural recruitment programs and their perceived influence on medical students. DESIGN Two original questionnaires delivered electronically, one to medical students and the other to recruiters in rural Ontario communities. SETTING Ontario, Canada. PARTICIPANTS All 525 medical students enrolled in the Schulich School of Medicine & Dentistry at the University of Western Ontario in London and physician recruiters in 71 rural communities in Ontario were invited to participate in the study. MAIN OUTCOME MEASURES The factors that influence medical students to consider rural practice, strategies used by recruiters, and student perceptions of the ethical appropriateness of both. RESULTS The questionnaire was completed by 42.1% of medical students. Lifestyle considerations were an important influence for 93.1% of students. Themes from the qualitative analysis included the ethical appropriateness of financial considerations, economic forces, perceived disadvantages of rural practice, competition between communities, and lack of altruism. Responses were received from recruiters in 43.7% of communities; of those, 92.9% offered financial incentives to attract prospective physicians. CONCLUSION Financial and lifestyle considerations are important influences on medical students’ choice to practise in rural communities. Most medical students felt incentive programs offered by rural communities were ethically appropriate. PMID:19155375

Recruiting medical students to rural practice: perspectives of medical students and rural recruiters.

PubMed

Jutzi, Leah; Vogt, Kelly; Drever, Erin; Nisker, Jeff

2009-01-01

To explore the strategies used by rural recruitment programs and their perceived influence on medical students. Two original questionnaires delivered electronically, one to medical students and the other to recruiters in rural Ontario communities. Ontario, Canada. All 525 medical students enrolled in the Schulich School of Medicine & Dentistry at the University of Western Ontario in London and physician recruiters in 71 rural communities in Ontario were invited to participate in the study. The factors that influence medical students to consider rural practice, strategies used by recruiters, and student perceptions of the ethical appropriateness of both. The questionnaire was completed by 42.1% of medical students. Lifestyle considerations were an important influence for 93.1% of students. Themes from the qualitative analysis included the ethical appropriateness of financial considerations, economic forces, perceived disadvantages of rural practice, competition between communities, and lack of altruism. Responses were received from recruiters in 43.7% of communities; of those, 92.9% offered financial incentives to attract prospective physicians. Financial and lifestyle considerations are important influences on medical students' choice to practise in rural communities. Most medical students felt incentive programs offered by rural communities were ethically appropriate.

MECHANISTIC AND SOURCE UNDERSTANDING OF PCDD/F FORMATION

EPA Science Inventory

The paper discusses mechanistic and source understanding of polychlorinated dibenzo-p-dioxin and dibenzofuran (PCDD/F) formation. (NOTE: Considerable research effort has been expended over the last 15-plus years to understand how combustion sources result in formation of PCDDs/F...

Open Source Vision

ERIC Educational Resources Information Center

Villano, Matt

2006-01-01

Increasingly, colleges and universities are turning to open source as a way to meet their technology infrastructure and application needs. Open source has changed life for visionary CIOs and their campus communities nationwide. The author discusses what these technologists see as the benefits--and the considerations.

Correspondence: In support of the IES method of evaluating light source colour rendition

DOE PAGES

Ashdown, I.; Aviles, G.; Bennett, L.; ...

2015-11-20

In this editorial, written as an open letter to the lighting community, we stand in support of widespread adoption of TM-30-15: The IES Method of Evaluating Light Source Color Rendition. We introduce important considerations related to light source color rendition, define the need for a new method of evaluation, provide a high-level overview of the IES method, discuss some of the practical considerations related to the development of the IES method and the consensus process, and conclude by inviting you to join us in support of the new measures and graphics described in TM-30-15.

Development of Cross-Assembly Phage PCR-Based Methods for Human Fecal Source Identification

EPA Science Inventory

Technologies that can characterize human fecal pollution in environmental waters offer many advantages over traditional general indicator approaches. However, many human-associated methods cross-react with non-human animal sources and lack suitable sensitivity for fecal source id...

Examining the Evolution of Paid Parental Leave.

PubMed

Sladek, Carol

While the United States continues to be the only developed nation without mandated paid maternity leave, U.S. employers are blazing their own trail for new parents. This article defines parental leave, explains what's driving the increased interest in paid parental leave among employers offering it and discusses how paid parental leave can benefit employers and employees alike. Finally, the author discusses why not all employers are offering these benefits as well as considerations for employers contemplating whether paid parental leave is right for them.

Using narratives and storytelling to communicate science with nonexpert audiences.

PubMed

Dahlstrom, Michael F

2014-09-16

Although storytelling often has negative connotations within science, narrative formats of communication should not be disregarded when communicating science to nonexpert audiences. Narratives offer increased comprehension, interest, and engagement. Nonexperts get most of their science information from mass media content, which is itself already biased toward narrative formats. Narratives are also intrinsically persuasive, which offers science communicators tactics for persuading otherwise resistant audiences, although such use also raises ethical considerations. Future intersections of narrative research with ongoing discussions in science communication are introduced.

Using narratives and storytelling to communicate science with nonexpert audiences

PubMed Central

Dahlstrom, Michael F.

2014-01-01

Although storytelling often has negative connotations within science, narrative formats of communication should not be disregarded when communicating science to nonexpert audiences. Narratives offer increased comprehension, interest, and engagement. Nonexperts get most of their science information from mass media content, which is itself already biased toward narrative formats. Narratives are also intrinsically persuasive, which offers science communicators tactics for persuading otherwise resistant audiences, although such use also raises ethical considerations. Future intersections of narrative research with ongoing discussions in science communication are introduced. PMID:25225368

Designing health insurance market constructs for shared responsibility: insights from California.

PubMed

Curtis, Rick; Neuschler, Ed

2009-01-01

Moving toward universal participation in health insurance using a "shared responsibility" approach requires new, more accessible, and more efficient ways for people who are not offered employer coverage to obtain coverage. California's recent health reform plan-which failed to pass-incorporated individual market reform and choice-pool constructs to achieve critically important risk spreading, assure solvency, and reduce cost shifts. These measures, as well as the considerations that led to their design, offer important insights for health reform at the federal level.

Cardiac imaging: does radiation matter?

PubMed Central

Einstein, Andrew J.; Knuuti, Juhani

2012-01-01

The use of ionizing radiation in cardiovascular imaging has generated considerable discussion. Radiation should not be considered in isolation, but rather in the context of a careful examination of the benefits, risks, and costs of cardiovascular imaging. Such consideration requires an understanding of some fundamental aspects of the biology, physics, epidemiology, and terminology germane to radiation, as well as principles of radiological protection. This paper offers a concise, contemporary perspective on these areas by addressing pertinent questions relating to radiation and its application to cardiac imaging. PMID:21828062

Justification and radiology: some ethical considerations.

PubMed

Sia, Santiago

2009-07-01

This paper, which seeks to address the issue of justification in radiology, intends firstly to comment on the current discussion of the ethical foundation of radiological practice that focuses on the move from utilitarianism to the rights-centred criterion. Secondly, and this constitutes the bulk of the paper, it aims to offer a philosophical perspective, which is hoped will lead to a consideration of certain specific areas in ethical decision-making in the attempts here to deal with the main issue of justification in radiology.

Sources of Assistance.

ERIC Educational Resources Information Center

Ahumada, Martin M.; Hefferlin, JB Lon

1986-01-01

Information about materials on environmental scanning is offered. Suggestions about sources of data for scanning are provided, organized into six facets of the environment: demographic, economic, political, organizational, technological, and social-cultural. (MLW)

Assessing the number of fire fatalities in a defined population.

PubMed

Jonsson, Anders; Bergqvist, Anders; Andersson, Ragnar

2015-12-01

Fire-related fatalities and injuries have become a growing governmental concern in Sweden, and a national vision zero strategy has been adopted stating that nobody should get killed or seriously injured from fires. There is considerable uncertainty, however, regarding the numbers of both deaths and injuries due to fires. Different national sources present different numbers, even on deaths, which obstructs reliable surveillance of the problem over time. We assume the situation is similar in other countries. This study seeks to assess the true number of fire-related deaths in Sweden by combining sources, and to verify the coverage of each individual source. By doing so, we also wish to demonstrate the possibilities of improved surveillance practices. Data from three national sources were collected and matched; a special database on fatal fires held by The Swedish Contingencies Agency (nationally responsible for fire prevention), a database on forensic medical examinations held by the National Board of Forensic Medicine, and the cause of death register held by the Swedish National Board of Health and Welfare. The results disclose considerable underreporting in the single sources. The national database on fatal fires, serving as the principal source for policy making on fire prevention matters, underestimates the true situation by 20%. Its coverage of residential fires appears to be better than other fires. Systematic safety work and informed policy-making presuppose access to correct and reliable numbers. By combining several different sources, as suggested in this study, the national database on fatal fires is now considerably improved and includes regular matching with complementary sources.

41 CFR 304-3.13 - After I begin travel to a meeting, what should I do if a non-Federal source offers to pay for one...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false After I begin travel to a meeting, what should I do if a non-Federal source offers to pay for one or more of my travel expenses without my or my agency's prior knowledge? 304-3.13 Section 304-3.13 Public Contracts and Property Management Federal Travel Regulation System...

Perspectives on Pricing.

ERIC Educational Resources Information Center

Litten, Larry H.

1986-01-01

The most provocative perspectives on pricing for colleges and universities have come from the introduction of marketing into higher education. A brief review of these developments is offered to serve as an orientation for the consideration of pricing issues per se. (Author/MLW)

Organizational Contexts and Texts: The Redesign of the Midwest Bell Telephone Bill.

ERIC Educational Resources Information Center

Keller-Cohen, Deborah

1987-01-01

Offers a retrospective view of organizational factors affecting the redesign of the Midwest Bell Telephone Bill. Shows how financial considerations, organizational time frame, and employee training and experience influenced the bill's development process. (MM)

49 CFR 375.203 - What actions of an individual shipper may limit or reduce my normal liability?

Code of Federal Regulations, 2010 CFR

2010-10-01

... PROTECTION REGULATIONS Before Offering Services to My Customers Liability Considerations § 375.203 What... includes perishable, dangerous, or hazardous articles in the shipment without your knowledge, you need not...

Managing livestock using animal behavior: Mixed-species stocking and flerds

USDA-ARS?s Scientific Manuscript database

Mixed-species stocking can foster sound landscape management while offering economic and ecological advantages compared to mono-species stocking. Producers contemplating a mixed-species enterprise should reflect on several considerations before implementing this animal management strategy. Factors...

Teaching Probability: A Socio-Constructivist Perspective

ERIC Educational Resources Information Center

Sharma, Sashi

2015-01-01

There is a considerable and rich literature on students' misconceptions in probability. However, less attention has been paid to the development of students' probabilistic thinking in the classroom. This paper offers a sequence, grounded in socio-constructivist perspective for teaching probability.

The High Jump: Transition Issues of Learning Disabled Students and Their Parents.

ERIC Educational Resources Information Center

Ness, Jean E.

1989-01-01

Issues that face learning-disabled students and their parents during the transition from a secondary to a postsecondary setting are explored, and recommendations are offered for consideration in resolving problems during this period. (JDD)

Designing Clinical Remediation Programs.

ERIC Educational Resources Information Center

Oleszewski, Susan C.

1989-01-01

Elements and considerations in the provision of effective remediation for optometry students not achieving in clinical competence are discussed. Remediation of technical, cognitive, and noncognitive skills are included. A course in professional communication offered by the Pennsylvania College of Optometry is described. (MSE)

Sources of Foods That Are Ready-to-Consume ('Grazing Environments') Versus Requiring Additional Preparation ('Grocery Environments'): Implications for Food-Environment Research and Community Health.

PubMed

Lucan, Sean C; Maroko, Andrew R; Seitchik, Jason L; Yoon, Don; Sperry, Luisa E; Schechter, Clyde B

2018-03-14

Local businesses that offer foods may create different 'grazing environments' (characterized by sources of ready-to-consume foods) and 'grocery environments' (characterized by source of foods for later preparation). Such environments may be relevant to different populations at different times and may vary by neighborhood. In neighborhoods within two demographically distinct areas of the Bronx, NY [Area A (higher-poverty, greater minority representation, lesser vehicle ownership) vs. Area B], researchers assessed all storefront businesses for food offerings. Food offerings could be ready-to-consume or require additional preparation. 'Healthful' offerings included fruits and vegetables, whole grains, and nuts; 'less-healthful' offerings included 'refined sweets' and 'salty/fatty fare.' 'Food businesses' (those primarily focused on selling food) were distinguished from 'other businesses' (not focused primarily on food selling). Area A had a higher percentage of street segments on which foods were available (28.6% vs. 6.9% in Area B; difference 21.7% points [95% CI 17.0, 26.5]) and a higher percentage of businesses offering foods (46.9% vs. 41.7% in Area B; difference 5.2% points [95% CI - 2.0, 12.4]). 'Less-healthful' items predominated in both 'grazing environments' and overall environments ('grazing' plus 'grocery environments'; the environments researchers typically measure) in both Areas A and B. 'Other businesses' represented about 2/3 of all businesses and accounted for nearly 1/3 of all the businesses offering food in both geographic areas. The lower-income area with greater minority representation and less private transportation had more businesses offering foods on more streets. There was near-perfect overlap between 'grazing environments' and overall environments in both geographic areas. Future research should consider the extent of 'grazing' and 'grocery environments,' and when each might be most relevant to populations of interest.

Consideration of Fugitive Emissions in Major Source Determinations

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Stem Cell Banking for Regenerative and Personalized Medicine

PubMed Central

Harris, David T.

2014-01-01

Regenerative medicine, tissue engineering and gene therapy offer the opportunity to treat and cure many of today’s intractable afflictions. These approaches to personalized medicine often utilize stem cells to accomplish these goals. However, stem cells can be negatively affected by donor variables such as age and health status at the time of collection, compromising their efficacy. Stem cell banking offers the opportunity to cryogenically preserve stem cells at their most potent state for later use in these applications. Practical stem cell sources include bone marrow, umbilical cord blood and tissue, and adipose tissue. Each of these sources contains stem cells that can be obtained from most individuals, without too much difficulty and in an economical fashion. This review will discuss the advantages and disadvantages of each stem cell source, factors to be considered when contemplating banking each stem cell source, the methodology required to bank each stem cell source, and finally, current and future clinical uses of each stem cell source. PMID:28548060

Endophytic Fungi—Alternative Sources of Cytotoxic Compounds: A Review

PubMed Central

Uzma, Fazilath; Mohan, Chakrabhavi D.; Hashem, Abeer; Konappa, Narasimha M.; Rangappa, Shobith; Kamath, Praveen V.; Singh, Bhim P.; Mudili, Venkataramana; Gupta, Vijai K.; Siddaiah, Chandra N.; Chowdappa, Srinivas; Alqarawi, Abdulaziz A.; Abd_Allah, Elsayed F.

2018-01-01

Cancer is a major cause of death worldwide, with an increasing number of cases being reported annually. The elevated rate of mortality necessitates a global challenge to explore newer sources of anticancer drugs. Recent advancements in cancer treatment involve the discovery and development of new and improved chemotherapeutics derived from natural or synthetic sources. Natural sources offer the potential of finding new structural classes with unique bioactivities for cancer therapy. Endophytic fungi represent a rich source of bioactive metabolites that can be manipulated to produce desirable novel analogs for chemotherapy. This review offers a current and integrative account of clinically used anticancer drugs such as taxol, podophyllotoxin, camptothecin, and vinca alkaloids in terms of their mechanism of action, isolation from endophytic fungi and their characterization, yield obtained, and fungal strain improvement strategies. It also covers recent literature on endophytic fungal metabolites from terrestrial, mangrove, and marine sources as potential anticancer agents and emphasizes the findings for cytotoxic bioactive compounds tested against specific cancer cell lines. PMID:29755344

Natural disasters, climate change and mental health considerations for rural Australia.

PubMed

Morrissey, Shirley A; Reser, Joseph P

2007-04-01

This paper addresses a very salient feature of rural life and landscapes in Australia, natural disasters, and offers a psychological perspective on individual and community perceptions, responses, preparedness and planning. The convergent perspective offered reflects research and practice findings and insights from social and environmental psychology, as well as clinical, health and community psychology. The objective is to briefly characterise how these psychological approaches frame the psychological and social reality of these threats and events, and to canvas what insights and evidence-based best practice psychology have to offer allied professionals and paraprofessionals, and rural communities, as they experience and come to terms with the vagaries and extremes of the Australian environment.

Mini-conference on helicon plasma sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scime, E. E.; Keesee, A. M.; Boswell, R. W.

2008-05-15

The first two sessions of this mini-conference focused attention on two areas of helicon source research: The conditions for optimal helicon source performance and the origins of energetic electrons and ions in helicon source plasmas. The final mini-conference session reviewed novel applications of helicon sources, such as mixed plasma source systems and toroidal helicon sources. The session format was designed to stimulate debate and discussion, with considerable time available for extended discussion.

GO2OGS 1.0: a versatile workflow to integrate complex geological information with fault data into numerical simulation models

NASA Astrophysics Data System (ADS)

Fischer, T.; Naumov, D.; Sattler, S.; Kolditz, O.; Walther, M.

2015-11-01

We offer a versatile workflow to convert geological models built with the ParadigmTM GOCAD© (Geological Object Computer Aided Design) software into the open-source VTU (Visualization Toolkit unstructured grid) format for usage in numerical simulation models. Tackling relevant scientific questions or engineering tasks often involves multidisciplinary approaches. Conversion workflows are needed as a way of communication between the diverse tools of the various disciplines. Our approach offers an open-source, platform-independent, robust, and comprehensible method that is potentially useful for a multitude of environmental studies. With two application examples in the Thuringian Syncline, we show how a heterogeneous geological GOCAD model including multiple layers and faults can be used for numerical groundwater flow modeling, in our case employing the OpenGeoSys open-source numerical toolbox for groundwater flow simulations. The presented workflow offers the chance to incorporate increasingly detailed data, utilizing the growing availability of computational power to simulate numerical models.

Performance data for a terrestrial solar photovoltaic/water electrolysis experiment

NASA Technical Reports Server (NTRS)

Costogue, E. N.; Yasui, R. K.

1977-01-01

A description is presented of the equipment used in the experiment, taking into account the surplus solar panel from the Mariner 4 spacecraft which was used as a solar array source and an electrolytic hydrogen generator. Attention is also given to operational considerations and performance data, system considerations and aspects of optimization, and large-scale hydrogen production considerations.

Considerations for ceramic inlays in posterior teeth: a review

PubMed Central

Hopp, Christa D; Land, Martin F

2013-01-01

This review of ceramic inlays in posterior teeth includes a review of the history of ceramic restorations, followed by common indications and contraindications for their use. A discussion on the potential for tooth wear is followed by a review of recommended preparation design considerations, fabrication methods, and material choices. Despite the improved materials available for fabrication of porcelain inlays, fracture remains a primary mode of inlay failure. Therefore, a brief discussion on strengthening methods for ceramics is included. The review concludes with a section on luting considerations, and offers the clinician specific recommendations for luting procedures. In conclusion, inlay success rates and longevity, as reported in the literature, are summarized. PMID:23750101

Tenth International Colloquium on UV and X-Ray Spectroscopy of Astrophysical and Laboratory Plasmas

NASA Astrophysics Data System (ADS)

Silver, Eric H.; Kahn, Steven M.

UV and X-ray spectroscopy of astrophysical and laboratory plasmas draws interest from many disciplines. Contributions from international specialists are collected together in this book from a timely recent conference. In astrophysics, the Hubble Space Telescope, Astro 1 and ROSAT observatories are now providing UV and X-ray spectra and images of cosmic sources in unprecedented detail, while the Yohkoh mission recently collected superb data on the solar corona. In the laboratory, the development of ion-trap facilities and novel laser experiments are providing vital new data on high temperature plasmas. Recent innovations in the technology of spectroscopic instrumentation are discussed. These papers constitute an excellent up-to-date review of developments in short-wavelength spectroscopy and offer a solid introduction to its theoretical and experimental foundations. These proceedings give an up-to-date review of developments in short-wavelength spectroscopy and offer a solid introduction to its theoretical and experimental foundations. Various speakers presented some of the first results from the high resolution spectrograph on the Hubble Space Telescope, the high sensitivity far ultraviolet and X-ray spectrometers of the ASTRO 1 Observatory, the imaging X-ray spectrometer on the ROSAT Observatory, and the high resolution solar X-ray spectrometer on Yohkoh. The development of ion trap devices had brought about a revolution in laboratory investigations of atomic processes in highly charged atoms. X-ray laser experiments had not only yielded considerable insight into electron ion interactions in hot dense plasmas, but also demonstrated the versatility of laser plasmas as laboratory X-ray sources. Such measurements also motivated and led to refinements in the development of large-scale atomic and molecular codes. On the instrumental side, the design and development of the next series of very powerful short wavelength observatories had generated a large number of technological innovations in both dispersive and nondispersive spectroscopic instrumentation.

DNA barcoding as a tool for Great Lakes biological assessment

EPA Science Inventory

Enumerating organisms found in water samples in support of biodiversity and biological condition assessment is a mainstay of aquatic ecology, yet can require considerable resources and expertise. DNA-based identification of mixed-organism samples offers the potential to greatly ...

Integrating Physically Handicapped Pupils.

ERIC Educational Resources Information Center

Hodgson, Ann

1984-01-01

Intended for regular class teachers working with mainstreamed physically handicapped pupils, the article offers guidelines regarding school organization, conditions directly affecting the pupil, and classroom considerations. A brief review of the major conditions (such as allergies, cerebral palsy, and muscular dystrophy) is presented. (CL)

The Gifted and Honors Program at Ridgeroad Jr. High.

ERIC Educational Resources Information Center

Moody, Bonnie

1984-01-01

Describes a science program for honors students that offers a blend of both teacher-directed and student-directed activities. Includes information on instructional strategies used, independent student study projects, financial considerations, grading, and student reaction to the program. (JN)

48 CFR 48.101 - General.

Code of Federal Regulations, 2013 CFR

2013-10-01

... engineering effort is applied to areas of the contract that offer opportunities for considerable savings... ENGINEERING Policies and Procedures 48.101 General. (a) Value engineering is the formal technique by which... performing more economically. Value engineering attempts to eliminate, without impairing essential functions...

48 CFR 48.101 - General.

Code of Federal Regulations, 2014 CFR

2014-10-01

... engineering effort is applied to areas of the contract that offer opportunities for considerable savings... ENGINEERING Policies and Procedures 48.101 General. (a) Value engineering is the formal technique by which... performing more economically. Value engineering attempts to eliminate, without impairing essential functions...

48 CFR 48.101 - General.

Code of Federal Regulations, 2012 CFR

2012-10-01

... engineering effort is applied to areas of the contract that offer opportunities for considerable savings... ENGINEERING Policies and Procedures 48.101 General. (a) Value engineering is the formal technique by which... performing more economically. Value engineering attempts to eliminate, without impairing essential functions...

CACD Journal; Volume 12, 1991-92.

ERIC Educational Resources Information Center

CACD Journal, 1992

1992-01-01

Along with messages from the editor and CACD's president, this issue offers: (1) "Discrimination, Disability, and Cultural Considerations: Implications for Counselors (Brodwin, Hong and Soriano); (2) "New Majority Student Ratings of Counselor Utilization and Efficacy" (Aros and Harper); (3) School Counselors: An Endangered…

Students with Shunts: Program Considerations.

ERIC Educational Resources Information Center

French, Ron; And Others

1997-01-01

Examines how the medical condition of hydrocephalus can affect physical education students and physical education programs, and stresses the need to provide physical educators with information on students' medical conditions. Describes hydrocephalus and its treatment with ventricular peritoneal shunts, and offers suggestions on modifying…

Understanding private sector antimalarial distribution chains: a cross-sectional mixed methods study in six malaria-endemic countries.

PubMed

Palafox, Benjamin; Patouillard, Edith; Tougher, Sarah; Goodman, Catherine; Hanson, Kara; Kleinschmidt, Immo; Rueda, Sergio Torres; Kiefer, Sabine; O'Connell, Kathryn A; Zinsou, Cyprien; Phok, Sochea; Akulayi, Louis; Arogundade, Ekundayo; Buyungo, Peter; Mpasela, Felton; Chavasse, Desmond

2014-01-01

Private for-profit outlets are important treatment sources for malaria in most endemic countries. However, these outlets constitute only the last link in a chain of businesses that includes manufacturers, importers and wholesalers, all of which influence the availability, price and quality of antimalarials patients can access. We present evidence on the composition, characteristics and operation of these distribution chains and of the businesses that comprise them in six endemic countries (Benin, Cambodia, Democratic Republic of Congo, Nigeria, Uganda and Zambia). We conducted nationally representative surveys of antimalarial wholesalers during 2009-2010 using an innovative sampling approach that captured registered and unregistered distribution channels, complemented by in-depth interviews with a range of stakeholders. Antimalarial distribution chains were pyramidal in shape, with antimalarials passing through a maximum of 4-6 steps between manufacturer and retailer; however, most likely pass through 2-3 steps. Less efficacious non-artemisinin therapies (e.g. chloroquine) dominated weekly sales volumes among African wholesalers, while volumes for more efficacious artemisinin-based combination therapies (ACTs) were many times smaller. ACT sales predominated only in Cambodia. In all countries, consumer demand was the principal consideration when selecting products to stock. Selling prices and reputation were key considerations regarding supplier choice. Business practices varied across countries, with large differences in the proportions of wholesalers offering credit and delivery services to customers, and the types of distribution models adopted by businesses. Regulatory compliance also varied across countries, particularly with respect to licensing. The proportion of wholesalers possessing any up-to-date licence from national regulators was lowest in Benin and Nigeria, where vendors in traditional markets are important antimalarial supply sources. The structure and characteristics of antimalarial distribution chains vary across countries; therefore, understanding the wholesalers that comprise them should inform efforts aiming to improve access to quality treatment through the private sector.

Understanding Private Sector Antimalarial Distribution Chains: A Cross-Sectional Mixed Methods Study in Six Malaria-Endemic Countries

PubMed Central

Palafox, Benjamin; Patouillard, Edith; Tougher, Sarah; Goodman, Catherine; Hanson, Kara; Kleinschmidt, Immo; Rueda, Sergio Torres; Kiefer, Sabine; O’Connell, Kathryn A.; Zinsou, Cyprien; Phok, Sochea; Akulayi, Louis; Arogundade, Ekundayo; Buyungo, Peter; Mpasela, Felton; Chavasse, Desmond

2014-01-01

Background Private for-profit outlets are important treatment sources for malaria in most endemic countries. However, these outlets constitute only the last link in a chain of businesses that includes manufacturers, importers and wholesalers, all of which influence the availability, price and quality of antimalarials patients can access. We present evidence on the composition, characteristics and operation of these distribution chains and of the businesses that comprise them in six endemic countries (Benin, Cambodia, Democratic Republic of Congo, Nigeria, Uganda and Zambia). Methods and Findings We conducted nationally representative surveys of antimalarial wholesalers during 2009–2010 using an innovative sampling approach that captured registered and unregistered distribution channels, complemented by in-depth interviews with a range of stakeholders. Antimalarial distribution chains were pyramidal in shape, with antimalarials passing through a maximum of 4–6 steps between manufacturer and retailer; however, most likely pass through 2–3 steps. Less efficacious non-artemisinin therapies (e.g. chloroquine) dominated weekly sales volumes among African wholesalers, while volumes for more efficacious artemisinin-based combination therapies (ACTs) were many times smaller. ACT sales predominated only in Cambodia. In all countries, consumer demand was the principal consideration when selecting products to stock. Selling prices and reputation were key considerations regarding supplier choice. Business practices varied across countries, with large differences in the proportions of wholesalers offering credit and delivery services to customers, and the types of distribution models adopted by businesses. Regulatory compliance also varied across countries, particularly with respect to licensing. The proportion of wholesalers possessing any up-to-date licence from national regulators was lowest in Benin and Nigeria, where vendors in traditional markets are important antimalarial supply sources. Conclusions The structure and characteristics of antimalarial distribution chains vary across countries; therefore, understanding the wholesalers that comprise them should inform efforts aiming to improve access to quality treatment through the private sector. PMID:24699934

A Study of Biblical Sources of Management Principles.

DTIC Science & Technology

1976-07-01

to, currently identified and accepted management principles. The remaining five principles found in the Biblical source have definite United States Air Force application and are offered as proposed principles of management .

Wireless Power Transfer for Space Applications

NASA Technical Reports Server (NTRS)

Ramos, Gabriel Vazquez; Yuan, Jiann-Shiun

2011-01-01

This paper introduces an implementation for magnetic resonance wireless power transfer for space applications. The analysis includes an equivalent impedance study, loop material characterization, source/load resonance coupling technique, and system response behavior due to loads variability. System characterization is accomplished by executing circuit design from analytical equations and simulations using Matlab and SPICE. The theory was validated by a combination of different experiments that includes loop material consideration, resonance coupling circuits considerations, electric loads considerations and a small scale proof-of-concept prototype. Experiment results shows successful wireless power transfer for all the cases studied. The prototype provided about 4.5 W of power to the load at a separation of -5 cm from the source using a power amplifier rated for 7 W.

Intellectual disability health content within nursing curriculum: An audit of what our future nurses are taught.

PubMed

Trollor, Julian N; Eagleson, Claire; Turner, Beth; Salomon, Carmela; Cashin, Andrew; Iacono, Teresa; Goddard, Linda; Lennox, Nicholas

2016-10-01

Individuals with intellectual disability experience chronic and complex health issues, but face considerable barriers to healthcare. One such barrier is inadequate education of healthcare professionals. To establish the quantity and nature of intellectual disability content offered within Australian nursing degree curricula. A two-phase national audit of nursing curriculum content was conducted using an interview and online survey. Australian nursing schools offering pre-registration courses. Pre-registration course coordinators from 31 universities completed the Phase 1 interview on course structure. Unit coordinators and teaching staff from 15 universities in which intellectual disability content was identified completed the Phase 2 online survey. Quantity of compulsory and elective intellectual disability content offered (units and teaching time) and the nature of the content (broad categories, specific topics, and inclusive teaching) were audited using an online survey. Over half (52%) of the schools offered no intellectual disability content. For units of study that contained some auditable intellectual disability content, the area was taught on average for 3.6h per unit of study. Units were evenly distributed across the three years of study. Just three participating schools offered 50% of all units audited. Clinical assessment skills, and ethics and legal issues were most frequently taught, while human rights issues and preventative health were poorly represented. Only one nursing school involved a person with intellectual disability in content development or delivery. Despite significant unmet health needs of people with intellectual disability, there is considerable variability in the teaching of key intellectual disability content, with many gaps evident. Equipping nursing students with skills in this area is vital to building workforce capacity. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

Solar Power Satellites: Reconsideration as Renewable Energy Source Based on Novel Approaches

NASA Astrophysics Data System (ADS)

Ellery, Alex

2017-04-01

Solar power satellites (SPS) are a solar energy generation mechanism that captures solar energy in space and converts this energy into microwave for transmission to Earth-based rectenna arrays. They offer a constant, high integrated energy density of 200 W/m2 compared to <10 W/m2 for other renewable energy sources. Despite this promise as a clean energy source, SPS have been relegated out of consideration due to their enormous cost and technological challenge. It has been suggested that for solar power satellites to become economically feasible, launch costs must decrease from their current 20,000/kg to <200/kg. Even with the advent of single-stage-to-orbit launchers which propose launch costs dropping to 2,000/kg, this will not be realized. Yet, the advantages of solar power satellites are many including the provision of stable baseload power. Here, I present a novel approach to reduce the specific cost of solar power satellites to 1/kg by leveraging two enabling technologies - in-situ resource utilization of lunar material and 3D printing of this material. Specifically, we demonstrate that electric motors may be constructed from lunar material through 3D printing representing a major step towards the development of self-replicating machines. Such machines have the capacity to build solar power satellites on the Moon, thereby bypassing the launch cost problem. The productive capacity of self-replicating machines favours the adoption of large constellations of small solar power satellites. This opens up additional clean energy options for combating climate change by meeting the demands for future global energy.

Advanced Light Source Activity Report 2002

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duque, Theresa; Greiner, Annette; Moxon, Elizabeth

2003-06-12

This annual report of the Advanced Light Source details science highlights and facility improvements during the year. It also offers information on events sponsored by the facility, technical specifications, and staff and publication information.

Optical Imaging of Ionizing Radiation from Clinical Sources

PubMed Central

Shaffer, Travis M.; Drain, Charles Michael

2016-01-01

Nuclear medicine uses ionizing radiation for both in vivo diagnosis and therapy. Ionizing radiation comes from a variety of sources, including x-rays, beam therapy, brachytherapy, and various injected radionuclides. Although PET and SPECT remain clinical mainstays, optical readouts of ionizing radiation offer numerous benefits and complement these standard techniques. Furthermore, for ionizing radiation sources that cannot be imaged using these standard techniques, optical imaging offers a unique imaging alternative. This article reviews optical imaging of both radionuclide- and beam-based ionizing radiation from high-energy photons and charged particles through mechanisms including radioluminescence, Cerenkov luminescence, and scintillation. Therapeutically, these visible photons have been combined with photodynamic therapeutic agents preclinically for increasing therapeutic response at depths difficult to reach with external light sources. Last, new microscopy methods that allow single-cell optical imaging of radionuclides are reviewed. PMID:27688469

Renewable Energy for the Next Generation

ERIC Educational Resources Information Center

Barton, Leslie

2005-01-01

Renewable energy is harnessed from natural and sustainable sources, like wind, sun and water. They offer a pollution-free, endless source of electricity that is crucial in the fight against climate change. Every unit of this "green" electricity directly replaces electricity normally generated from conventional polluting sources such as coal or…

Values Education and Some Suggestions to Teachers

ERIC Educational Resources Information Center

Demirhan Iscan, Canay

2011-01-01

This paper focuses on the process, approaches and teacher roles in values education and offers recommendations for teachers. It uses print materials and Internet sources on values education. These sources were analyzed and synthesized to reveal certain cases and/or opinions. In addition to contemporary sources, older reference materials were also…

Using Primary Source Documents.

ERIC Educational Resources Information Center

Mintz, Steven

2003-01-01

Explores the use of primary sources when teaching about U.S. slavery. Includes primary sources from the Gilder Lehrman Documents Collection (New York Historical Society) to teach about the role of slaves in the Revolutionary War, such as a proclamation from Lord Dunmore offering freedom to slaves who joined his army. (CMK)

10 CFR 470.16 - Cost sharing and funds from other sources.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Cost sharing and funds from other sources. 470.16 Section... § 470.16 Cost sharing and funds from other sources. Proposers are encouraged to offer to share in the... other entities to obtain supplemental funding. ...

Open Source Software Development and Lotka's Law: Bibliometric Patterns in Programming.

ERIC Educational Resources Information Center

Newby, Gregory B.; Greenberg, Jane; Jones, Paul

2003-01-01

Applies Lotka's Law to metadata on open source software development. Authoring patterns found in software development productivity are found to be comparable to prior studies of Lotka's Law for scientific and scholarly publishing, and offer promise in predicting aggregate behavior of open source developers. (Author/LRW)

An alternative approach to probabilistic seismic hazard analysis in the Aegean region using Monte Carlo simulation

NASA Astrophysics Data System (ADS)

Weatherill, Graeme; Burton, Paul W.

2010-09-01

The Aegean is the most seismically active and tectonically complex region in Europe. Damaging earthquakes have occurred here throughout recorded history, often resulting in considerable loss of life. The Monte Carlo method of probabilistic seismic hazard analysis (PSHA) is used to determine the level of ground motion likely to be exceeded in a given time period. Multiple random simulations of seismicity are generated to calculate, directly, the ground motion for a given site. Within the seismic hazard analysis we explore the impact of different seismic source models, incorporating both uniform zones and distributed seismicity. A new, simplified, seismic source model, derived from seismotectonic interpretation, is presented for the Aegean region. This is combined into the epistemic uncertainty analysis alongside existing source models for the region, and models derived by a K-means cluster analysis approach. Seismic source models derived using the K-means approach offer a degree of objectivity and reproducibility into the otherwise subjective approach of delineating seismic sources using expert judgment. Similar review and analysis is undertaken for the selection of peak ground acceleration (PGA) attenuation models, incorporating into the epistemic analysis Greek-specific models, European models and a Next Generation Attenuation model. Hazard maps for PGA on a "rock" site with a 10% probability of being exceeded in 50 years are produced and different source and attenuation models are compared. These indicate that Greek-specific attenuation models, with their smaller aleatory variability terms, produce lower PGA hazard, whilst recent European models and Next Generation Attenuation (NGA) model produce similar results. The Monte Carlo method is extended further to assimilate epistemic uncertainty into the hazard calculation, thus integrating across several appropriate source and PGA attenuation models. Site condition and fault-type are also integrated into the hazard mapping calculations. These hazard maps are in general agreement with previous maps for the Aegean, recognising the highest hazard in the Ionian Islands, Gulf of Corinth and Hellenic Arc. Peak Ground Accelerations for some sites in these regions reach as high as 500-600 cm s -2 using European/NGA attenuation models, and 400-500 cm s -2 using Greek attenuation models.

Internet Business Resources.

ERIC Educational Resources Information Center

Cronin, Mary J.

1993-01-01

Review of major information providers on the Internet that offer business resources focuses on U.S. government, United Nations, and European Community information and suggests sources for keeping current with new information offerings. Electronic bulletin boards, LC MARVEL, university Gophers, and TECnet are described; and access and subscription…

Green Processing Technologies for Improving Germinated Brown Rice Milk Beverages

USDA-ARS?s Scientific Manuscript database

Rice feeds approximately half the world’s population. Rice-derived beverages offer non-soy, lactose-free, hypoallergenic, cholesterol and gluten free value-added food sources. Rice milk beverages offer exceptional options for those with lactose intolerance, gluten sensitivities, obesity, heart dis...

48 CFR 15.101 - Best value continuum.

Code of Federal Regulations, 2010 CFR

2010-10-01

... risk of unsuccessful contract performance is minimal, cost or price may play a dominant role in source... performance risk, the more technical or past performance considerations may play a dominant role in source...

32 CFR 725.8 - Considerations in determining to grant or deny a request.

Code of Federal Regulations, 2013 CFR

2013-07-01

... rights, reveal the identity of an intelligence source or source of confidential information, conflict... a person who has acquired additional and separate knowledge or expertise wholly apart from...

32 CFR 725.8 - Considerations in determining to grant or deny a request.

Code of Federal Regulations, 2012 CFR

2012-07-01

... rights, reveal the identity of an intelligence source or source of confidential information, conflict... a person who has acquired additional and separate knowledge or expertise wholly apart from...

32 CFR 725.8 - Considerations in determining to grant or deny a request.

Code of Federal Regulations, 2011 CFR

2011-07-01

... rights, reveal the identity of an intelligence source or source of confidential information, conflict... a person who has acquired additional and separate knowledge or expertise wholly apart from...

32 CFR 725.8 - Considerations in determining to grant or deny a request.

Code of Federal Regulations, 2014 CFR

2014-07-01

... rights, reveal the identity of an intelligence source or source of confidential information, conflict... a person who has acquired additional and separate knowledge or expertise wholly apart from...

A Biological Basis for Generative Learning in Technology-and-Science Part I: A Theory of Learning.

ERIC Educational Resources Information Center

Schaverien, Lynette; Cosgrove, Mark

1999-01-01

Describes a theory of learning in which the brain is seen as a Darwinian machine. Argues that the generative heuristic underlying Darwinism offers considerable value for technology and science education. Contains 33 references. (Author/WRM)

47 CFR 76.1002 - Specific unfair practices prohibited.

Code of Federal Regulations, 2010 CFR

2010-10-01

... reasonable requirements for creditworthiness, offering of service, and financial stability and standards... classes of service in pricing based on credit considerations or financial stability, although any such... technology. Vendors are not permitted to manifest factors such as creditworthiness or financial stability in...

Supertitrations: High-Precision Methods.

ERIC Educational Resources Information Center

Guenther, W. B.

1988-01-01

Offers challenging work at a higher level of technique than most students meet in elementary laboratory work. Uses a combined weight and volumetric sequence not shown in textbooks. Notes modern rapid balances help lower evaporation loss during weighings. Discusses the balance, weights, and buoyancy considerations. (MVL)

Some Conditions for Cost Efficiency in Hypermedia.

ERIC Educational Resources Information Center

Westland, J. Christopher

1998-01-01

Models administrative and operating costs surrounding a hypermedia database and identifies seven conditions for the cost justification of hypermedia. Concludes that cost considerations aside, hypermedia offers significant data retrieval benefits in accessing text, video, still pictures, and sound, and provides substantially better human…

Impact injury to the pregnant female and fetus in lap belt restraint.

DOT National Transportation Integrated Search

1968-12-01

Although it has been well established that the lap (seat) belt offers considerable protection against injury or death in crash environments, there has long been controversy over the injury potential to the pregnant female. This question is of importa...

49 CFR 375.201 - What is my normal liability for loss and damage when I accept goods from an individual shipper?

Code of Federal Regulations, 2010 CFR

2010-10-01

...; CONSUMER PROTECTION REGULATIONS Before Offering Services to My Customers Liability Considerations § 375.201... Protection Obligation—In general, your liability is for the household goods that are lost, damaged, destroyed...

School Consolidation Survey: Iredell County: Mooresville, Statesville, North Carolina.

ERIC Educational Resources Information Center

Engelhardt and Engelhardt, Inc., Purdy Station, NY.

This document explores the feasibility of consolidating three North Carolina school districts into a single administrative unit. Factors analyzed include future population and enrollment growth, existing buildings and school building needs, program offerings, staff qualifications, administrative organization, and financial considerations of…

LIFE CYCLE DESIGN FRAMEWORK AND DEMONSTRATION PROJECTS - PROFILES OF AT&T AND ALLIED SIGNAL

EPA Science Inventory

This document offers guidance and practical experience for integrating environmental considerations into product system development. Life cycle design seeks to minimize the environmental burden associated with a product's life cycle from raw materials acquisition through manufact...

Specializations in Rehabilitation Counseling: One Program's Vision

ERIC Educational Resources Information Center

Bernacchio, Charles; Burker, Eileen J.; Falvo, Donna; Porter, Patricia; Carone, Stacia

2008-01-01

The option for specialization is explored to address expanding roles for rehabilitation counselors. Several important considerations are identified for Rehabilitation Counselor Education (RCE) program faculty opting for a specialization. Development of specialty tracks in psychiatric and developmental disabilities are offered as viable options for…

Notebook Computers Increase Communication.

ERIC Educational Resources Information Center

Carey, Doris M.; Sale, Paul

1994-01-01

Project FIT (Full Inclusion through Technology) provides notebook computers for children with severe disabilities. The computers offer many input and output options. Assessing the students' equipment needs is a complex process, requiring determination of communication goals and baseline abilities, and consideration of equipment features such as…

Working with the private sector for child health.

PubMed

Waters, Hugh; Hatt, Laurel; Peters, David

2003-06-01

Private sector providers are the most commonly consulted source of care for child illnesses in many countries, offering significant opportunities to expand the reach of essential child health services and products. Yet collaboration with private providers presents major challenges - the suitability and quality of the services they provide is often questionable and governments' capacity to regulate them is limited. This article assesses the actual and potential contributions of the private sector to child health, and classifies and evaluates public sector strategies to promote and rationalize the contributions of private sector actors. Governments and international organizations can use a variety of strategies to collaborate with and influence private sector actors to improve child health - including contracting, regulating, financing and social marketing, training, coordinating and informing the public. These mutually reinforcing strategies can both improve the quality of services currently delivered in the private sector, and expand and rationalize the coverage of these services. One lesson from this review is that the private sector is very heterogeneous. At the country level, feasible strategies depend on the potential of the different components of the private sector and the capacity of governments and their partners for collaboration. To date, experience with private sector strategies offers considerable promise for children's health, but also raises many questions about the feasibility and impact of these strategies. Where possible, future interventions should be designed as experiments, with careful assessment of the intervention design and the environment in which they are implemented.

Integrating ecosystem services analysis into scenario planning practice: accounting for street tree benefits with i-Tree valuation in Central Texas.

PubMed

Hilde, Thomas; Paterson, Robert

2014-12-15

Scenario planning continues to gain momentum in the United States as an effective process for building consensus on long-range community plans and creating regional visions for the future. However, efforts to integrate more sophisticated information into the analytical framework to help identify important ecosystem services have lagged in practice. This is problematic because understanding the tradeoffs of land consumption patterns on ecological integrity is central to mitigating the environmental degradation caused by land use change and new development. In this paper we describe how an ecosystem services valuation model, i-Tree, was integrated into a mainstream scenario planning software tool, Envision Tomorrow, to assess the benefits of public street trees for alternative future development scenarios. The tool is then applied to development scenarios from the City of Hutto, TX, a Central Texas Sustainable Places Project demonstration community. The integrated tool represents a methodological improvement for scenario planning practice, offers a way to incorporate ecosystem services analysis into mainstream planning processes, and serves as an example of how open source software tools can expand the range of issues available for community and regional planning consideration, even in cases where community resources are limited. The tool also offers room for future improvements; feasible options include canopy analysis of various future land use typologies, as well as a generalized street tree model for broader U.S. application. Copyright © 2014 Elsevier Ltd. All rights reserved.

Searching mixed DNA profiles directly against profile databases.

PubMed

Bright, Jo-Anne; Taylor, Duncan; Curran, James; Buckleton, John

2014-03-01

DNA databases have revolutionised forensic science. They are a powerful investigative tool as they have the potential to identify persons of interest in criminal investigations. Routinely, a DNA profile generated from a crime sample could only be searched for in a database of individuals if the stain was from single contributor (single source) or if a contributor could unambiguously be determined from a mixed DNA profile. This meant that a significant number of samples were unsuitable for database searching. The advent of continuous methods for the interpretation of DNA profiles offers an advanced way to draw inferential power from the considerable investment made in DNA databases. Using these methods, each profile on the database may be considered a possible contributor to a mixture and a likelihood ratio (LR) can be formed. Those profiles which produce a sufficiently large LR can serve as an investigative lead. In this paper empirical studies are described to determine what constitutes a large LR. We investigate the effect on a database search of complex mixed DNA profiles with contributors in equal proportions with dropout as a consideration, and also the effect of an incorrect assignment of the number of contributors to a profile. In addition, we give, as a demonstration of the method, the results using two crime samples that were previously unsuitable for database comparison. We show that effective management of the selection of samples for searching and the interpretation of the output can be highly informative. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Folates in lettuce: a pilot study

PubMed Central

Johansson, Madelene; Jägerstad, Margaretha; Frølich, Wenche

2007-01-01

Background Leafy vegetables are good sources of folates and food shops nowadays offer an increasing number of lettuce varieties. Objective To obtain data on the folate content and forms in common lettuce varieties and spinach sold in the Nordic countries, and to investigate effects of different storage conditions and preparations in the consumer's home or at lunchtime restaurants. Design Folate was analysed in eight different lettuce varieties and spinach using a validated high-performance liquid chromatographic method and the detected forms of folates were confirmed by a mass spectrometric detector [liquid chromatography–mass spectrometry (LC-MS)] following heat extraction, deconjugation with rat serum and purification by solid-phase extraction. Results Folate content, expressed in folic acid equivalents, in the lettuce samples varied six-fold, from 30 to 198 µg 100 g−1 on a fresh weight basis. The folate content was decreased by 14% after storage at 4°C for 8 days and by 2–40% after storage at 22°C for 2–4 h, depending on whether samples were stored as whole leaves, or small torn or cut pieces. LC-MS confirmed the identity of the folate forms: H4folate, 5-CH3-H4folate, 5-HCO-H4folate and 10-HCO-H4folate. Conclusion The considerable variation in folate content between varieties of lettuce in this pilot study, with one variety reaching the level found in spinach, indicates the potential to increase folate intake considerably by choosing folate-rich varieties of lettuce and storing at low temperatures.

Discovery of practical production processes for arylsulfur pentafluorides and their higher homologues, bis- and tris(sulfur pentafluorides): Beginning of a new era of “super-trifluoromethyl” arene chemistry and its industry

PubMed Central

Garrick, Lloyd M; Saito, Norimichi

2012-01-01

Summary Various arylsulfur pentafluorides, ArSF5, have long been desired in both academic and industrial areas, and ArSF5 compounds have attracted considerable interest in many areas such as medicines, agrochemicals, and other new materials, since the highly stable SF5 group is considered a “super-trifluoromethyl group” due to its significantly higher electronegativity and lipophilicity. This article describes the first practical method for the production of various arylsulfur pentafluorides and their higher homologues, bis- and tris(sulfur pentafluorides), from the corresponding diaryl disulfides or aryl thiols. The method consists of two steps: (Step 1) treatment of a diaryl disulfide or an aryl thiol with chlorine in the presence of an alkali metal fluoride, and (step 2) treatment of the resulting arylsulfur chlorotetrafluoride with a fluoride source, such as ZnF2, HF, and Sb(III/V) fluorides. The intermediate arylsulfur chlorotetrafluorides were isolated by distillation or recrystallization and characterized. The aspects of these new reactions are revealed and reaction mechanisms are discussed. As the method offers considerable improvement over previous methods in cost, yield, practicality, applicability, and large-scale production, the new processes described here can be employed as the first practical methods for the economical production of various arylsulfur pentafluorides and their higher homologues, which could then open up a new era of “super-trifluoromethyl” arene chemistry and its applications in many areas. PMID:22509218

Regulatory and ethical considerations for linking clinical and administrative databases.

PubMed

Dokholyan, Rachel S; Muhlbaier, Lawrence H; Falletta, John M; Jacobs, Jeffrey P; Shahian, David; Haan, Constance K; Peterson, Eric D

2009-06-01

Clinical data registries are valuable tools that support evidence development, performance assessment, comparative effectiveness studies, and the adoption of new treatments into routine clinical practice. Although these registries do not have important information on long-term therapies or clinical events, administrative claims databases offer a potentially valuable complement. This article focuses on the regulatory and ethical considerations that arise from the use of registry data for research, including linkage of clinical and administrative data sets. (1) Are such activities primarily designed for quality assessment and improvement, research, or both, as this determines the appropriate ethical and regulatory standards? (2) Does the submission of data to a central registry, which may subsequently be linked to other data sources, require review by the institutional review board (IRB) of each participating organization? (3) What levels and mechanisms of IRB oversight are appropriate for the existence of a linked central data repository and the specific studies that may subsequently be developed using it? (4) Under what circumstances are waivers of informed consent and Health Insurance Portability and Accountability Act authorization required? (5) What are the requirements for a limited data set that would qualify a research activity as not involving human subjects and thus not subject to further IRB review? The approaches outlined in this article represent a local interpretation of the regulations in the context of several clinical data registry projects and focuses on a specific case study of the Society of Thoracic Surgeons National Database.

Reasons for Journal Impact Factor Changes: Influence of Changing Source Items.

PubMed

Kiesslich, Tobias; Weineck, Silke B; Koelblinger, Dorothea

2016-01-01

Both the concept and the application of the impact factor (IF) have been subject to widespread critique, including concerns over its potential manipulation. This study provides a systematic analysis of significant journal Impact Factor changes, based on the relative contribution of either one or both variables of the IF equation (i.e. citations / articles as the numerator / denominator of the quotient). A cohort of JCR-listed journals which faced the most dramatic absolute IF changes between 2013 and 2014 (ΔIF ≥ 3.0, n = 49) was analyzed for the causes resulting in IF changes that theses journals have experienced in the last five years. Along with the variation by number of articles and citations, this analysis includes the relative change of both variables compared to each other and offers a classification of `valid`and `invalid`scenarios of IF variation in terms of the intended goal of the IF to measure journal quality. The sample cohort features a considerable incidence of IF increases (18%) which are qualified as `invalid`according to this classification because the IF increase is merely based on a favorably changing number of articles (denominator). The results of this analysis point out the potentially delusive effect of IF increases gained through effective shrinkage of publication output. Therefore, careful consideration of the details of the IF equation and possible implementation of control mechanisms versus the volatile factor of number of articles may help to improve the expressiveness of this metric.

Optimization of the pepsin digestion method for anisakids inspection in the fishing industry.

PubMed

Llarena-Reino, María; Piñeiro, Carmen; Antonio, José; Outeriño, Luis; Vello, Carlos; González, Ángel F; Pascual, Santiago

2013-01-31

During the last 50 years human anisakiasis has been rising while parasites have increased their prevalence at determined fisheries becoming an emergent major public health problem. Although artificial enzymatic digestion procedure by CODEX (STAN 244-2004: standard for salted Atlantic herring and salted sprat) is the recommended protocol for anisakids inspection, no international agreement has been achieved in veterinary and scientific digestion protocols to regulate this growing source of biological hazard in fish products. The aim of this work was to optimize the current artificial digestion protocol by CODEX with the purpose of offering a faster, more useful and safer procedure for factories workers, than the current one for anisakids detection. To achieve these objectives, the existing pepsin chemicals and the conditions of the digestion method were evaluated and assayed in fresh and frozen samples, both in lean and fatty fish species. Results showed that the new digestion procedure considerably reduces the assay time, and it is more handy and efficient (the quantity of the resulting residue was considerably lower after less time) than the widely used CODEX procedure. In conclusion, the new digestion method herein proposed based on liquid pepsin format is an accurate reproducible and user-friendly off-site tool, that can be useful in the implementation of screening programs for the prevention of human anisakiasis (and associated gastroallergic disorders) due to the consumption of raw or undercooked contaminated seafood products. Copyright © 2012 Elsevier B.V. All rights reserved.

Ongoing Horizontal and Vertical Transmission of Virulence Genes and papA Alleles among Escherichia coli Blood Isolates from Patients with Diverse-Source Bacteremia

PubMed Central

Johnson, James R.; O'Bryan, Timothy T.; Kuskowski, Michael; Maslow, Joel N.

2001-01-01

The phylogenetic distributions of multiple putative virulence factors (VFs) and papA (P fimbrial structural subunit) alleles among 182 Escherichia coli blood isolates from patients with diverse-source bacteremia were defined. Phylogenetic correspondence among these strains, the E. coli Reference (ECOR) collection, and other collections of extraintestinal pathogenic E. coli (ExPEC) was assessed. Although among the 182 bacteremia isolates phylogenetic group B2 predominated, exhibited the greatest concentration of individual VFs, and contained the largest number of familiar virulent clones, other phylogenetic groups exhibited greater concentrations of certain VFs than did group B2 and included several additional virulent clones. Certain of the newly detected VF genes, e.g., fyuA (yersiniabactin; 76%) and focG (F1C fimbriae; 25%), were as prevalent or more prevalent than their more familiar traditional counterparts, e.g., iut (aerobactin; 57%) and sfaS (S fimbriae; 14%), thus possibly offering additional useful targets for preventive interventions. Considerable diversity of VF profiles was observed at every level within the phylogenetic tree, including even within individual lineages. This suggested that many different pathways can lead to extraintestinal virulence in E. coli and that the evolution of ExPEC, which involves extensive horizontal transmission of VFs and continuous remodeling of pathogenicity-associated islands, is a highly active, ongoing process. PMID:11500406

Nonlinear damage detection in composite structures using bispectral analysis

NASA Astrophysics Data System (ADS)

Ciampa, Francesco; Pickering, Simon; Scarselli, Gennaro; Meo, Michele

2014-03-01

Literature offers a quantitative number of diagnostic methods that can continuously provide detailed information of the material defects and damages in aerospace and civil engineering applications. Indeed, low velocity impact damages can considerably degrade the integrity of structural components and, if not detected, they can result in catastrophic failure conditions. This paper presents a nonlinear Structural Health Monitoring (SHM) method, based on ultrasonic guided waves (GW), for the detection of the nonlinear signature in a damaged composite structure. The proposed technique, based on a bispectral analysis of ultrasonic input waveforms, allows for the evaluation of the nonlinear response due to the presence of cracks and delaminations. Indeed, such a methodology was used to characterize the nonlinear behaviour of the structure, by exploiting the frequency mixing of the original waveform acquired from a sparse array of sensors. The robustness of bispectral analysis was experimentally demonstrated on a damaged carbon fibre reinforce plastic (CFRP) composite panel, and the nonlinear source was retrieved with a high level of accuracy. Unlike other linear and nonlinear ultrasonic methods for damage detection, this methodology does not require any baseline with the undamaged structure for the evaluation of the nonlinear source, nor a priori knowledge of the mechanical properties of the specimen. Moreover, bispectral analysis can be considered as a nonlinear elastic wave spectroscopy (NEWS) technique for materials showing either classical or non-classical nonlinear behaviour.

Impact and quantification of the sources of error in DNA pooling designs.

PubMed

Jawaid, A; Sham, P

2009-01-01

The analysis of genome wide variation offers the possibility of unravelling the genes involved in the pathogenesis of disease. Genome wide association studies are also particularly useful for identifying and validating targets for therapeutic intervention as well as for detecting markers for drug efficacy and side effects. The cost of such large-scale genetic association studies may be reduced substantially by the analysis of pooled DNA from multiple individuals. However, experimental errors inherent in pooling studies lead to a potential increase in the false positive rate and a loss in power compared to individual genotyping. Here we quantify various sources of experimental error using empirical data from typical pooling experiments and corresponding individual genotyping counts using two statistical methods. We provide analytical formulas for calculating these different errors in the absence of complete information, such as replicate pool formation, and for adjusting for the errors in the statistical analysis. We demonstrate that DNA pooling has the potential of estimating allele frequencies accurately, and adjusting the pooled allele frequency estimates for differential allelic amplification considerably improves accuracy. Estimates of the components of error show that differential allelic amplification is the most important contributor to the error variance in absolute allele frequency estimation, followed by allele frequency measurement and pool formation errors. Our results emphasise the importance of minimising experimental errors and obtaining correct error estimates in genetic association studies.

Framing the policy debate over spirits excise tax in Poland.

PubMed

Zatonski, Mateusz; Hawkins, Benjamin; McKee, Martin

2018-06-01

Industry lobbying remains an obstacle to effective health-oriented alcohol policy. In 2013, an increase in excise tax on spirits was announced by the Polish government. This article presents a qualitative analysis of the public debate that ensued on the potential economic, health and social effects of the policy. It focuses on how competing groups, including industry actors, framed their position and sought to dominate the debate. Online archives of five Polish national newspapers, two spirits trade associations, and parliamentary and ministerial archives were searched. A thematic content analysis of the identified sources was conducted. The overall findings were compared with existing research on the framing of the Minimum Unit Pricing (MUP) debate in the UK. A total of 155 sources were analysed. Two main frames were identified: health, and economic. The spirits industry successfully promoted the economic frame in their own publications and in the media. The debate was dominated by arguments about potential growth of the grey market and losses in tax revenue that might result from the excise tax increase. The framing of the debate in Poland differed from the framing of the MUP debate in the United Kingdom. The Polish public health community was unsuccessful in making health considerations a significant element of the alcohol policy debate. The strategies pursued by UK health advocates offer lessons for how to make a more substantial impact on media coverage and promote health-oriented legislation.

Infrared imaging for tumor detection using antibodies conjugated magnetic nanoparticles

NASA Astrophysics Data System (ADS)

Levy, Arie; Gannot, Israel

2008-04-01

Thermography is a well known approach for cost effective early detection of concourse tumors. However, till now - more than 5 decades after its introduction - it is not considered as a primary tool for cancer early detection, mainly because its poor performance compared to other techniques. This work offers a new thermographic approach for tumor detection which is based on the use of antibody conjugated magnetic nanoparticles ("MNP") as a tumor specific marker. Wename this method "Thermal Beacon Thermography" ("TBT"), and it has the potential to provide considerable advantages over conventional thermographic approach. TBT approach is based on the fact that MNP are producing heat when subjected to an alternating magnetic field ("AMF"). Once these particles are injected to the patient blood stream, they specifically accumulate at the tumor site, providing a local heat source at the tumor that can be activated and deactivated by external control. This heat source can be used as a "thermal beacon" in order to detect and locate tumor by detecting temperature changes at the skin surface using an IR camera and comparing them to a set of pre-calculated numerical predictions. Experiments were conducted using an in vitro tissue model together with industrial inductive heating system and an IR camera. The results shows that this approach can specifically detect small tumor phantom (D=1.5mm) which was embedded below the surface of the tissue phantom.

Models for Deploying Open Source and Commercial Software to Support Earth Science Data Processing and Distribution

NASA Astrophysics Data System (ADS)

Yetman, G.; Downs, R. R.

2011-12-01

Software deployment is needed to process and distribute scientific data throughout the data lifecycle. Developing software in-house can take software development teams away from other software development projects and can require efforts to maintain the software over time. Adopting and reusing software and system modules that have been previously developed by others can reduce in-house software development and maintenance costs and can contribute to the quality of the system being developed. A variety of models are available for reusing and deploying software and systems that have been developed by others. These deployment models include open source software, vendor-supported open source software, commercial software, and combinations of these approaches. Deployment in Earth science data processing and distribution has demonstrated the advantages and drawbacks of each model. Deploying open source software offers advantages for developing and maintaining scientific data processing systems and applications. By joining an open source community that is developing a particular system module or application, a scientific data processing team can contribute to aspects of the software development without having to commit to developing the software alone. Communities of interested developers can share the work while focusing on activities that utilize in-house expertise and addresses internal requirements. Maintenance is also shared by members of the community. Deploying vendor-supported open source software offers similar advantages to open source software. However, by procuring the services of a vendor, the in-house team can rely on the vendor to provide, install, and maintain the software over time. Vendor-supported open source software may be ideal for teams that recognize the value of an open source software component or application and would like to contribute to the effort, but do not have the time or expertise to contribute extensively. Vendor-supported software may also have the additional benefits of guaranteed up-time, bug fixes, and vendor-added enhancements. Deploying commercial software can be advantageous for obtaining system or software components offered by a vendor that meet in-house requirements. The vendor can be contracted to provide installation, support and maintenance services as needed. Combining these options offers a menu of choices, enabling selection of system components or software modules that meet the evolving requirements encountered throughout the scientific data lifecycle.

Astrophysics Source Code Library -- Now even better!

NASA Astrophysics Data System (ADS)

Allen, Alice; Schmidt, Judy; Berriman, Bruce; DuPrie, Kimberly; Hanisch, Robert J.; Mink, Jessica D.; Nemiroff, Robert J.; Shamir, Lior; Shortridge, Keith; Taylor, Mark B.; Teuben, Peter J.; Wallin, John F.

2015-01-01

The Astrophysics Source Code Library (ASCL, ascl.net) is a free online registry of codes used in astronomy research. Indexed by ADS, it now contains nearly 1,000 codes and with recent major changes, is better than ever! The resource has a new infrastructure that offers greater flexibility and functionality for users, including an easier submission process, better browsing, one-click author search, and an RSS feeder for news. The new database structure is easier to maintain and offers new possibilities for collaboration. Come see what we've done!

Panama Canal Expansion Illustrates Need for Multimodal Near-Source Air Quality Assessment

EPA Science Inventory

The compelling issue raised is potential major changes in goods movement due to the Panama Canal expansion and considerations for near-source air quality. Near-source air quality may be affected both at near-port areas as well as along the freight transportation corridor.

20 CFR 416.924a - Considerations in determining disability for children.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., teachers, and other people who know you. (1) Medical evidence—(i) General. Medical evidence of your... consider test scores.) (iii) Medical sources. Medical sources will report their findings and observations..., including your teachers and therapists. When a medical source has accepted and relied on such information to...

20 CFR 416.924a - Considerations in determining disability for children.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., teachers, and other people who know you. (1) Medical evidence—(i) General. Medical evidence of your... consider test scores.) (iii) Medical sources. Medical sources will report their findings and observations..., including your teachers and therapists. When a medical source has accepted and relied on such information to...

20 CFR 416.924a - Considerations in determining disability for children.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., teachers, and other people who know you. (1) Medical evidence—(i) General. Medical evidence of your... consider test scores.) (iii) Medical sources. Medical sources will report their findings and observations..., including your teachers and therapists. When a medical source has accepted and relied on such information to...

20 CFR 416.924a - Considerations in determining disability for children.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., teachers, and other people who know you. (1) Medical evidence—(i) General. Medical evidence of your... consider test scores.) (iii) Medical sources. Medical sources will report their findings and observations..., including your teachers and therapists. When a medical source has accepted and relied on such information to...

20 CFR 416.924a - Considerations in determining disability for children.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., teachers, and other people who know you. (1) Medical evidence—(i) General. Medical evidence of your... consider test scores.) (iii) Medical sources. Medical sources will report their findings and observations..., including your teachers and therapists. When a medical source has accepted and relied on such information to...

The Snowballing Literature on Imiquimod-Induced Skin Inflammation in Mice: A Critical Appraisal

PubMed Central

Hawkes, Jason E.; Gudjonsson, Johann E.; Ward, Nicole L.

2016-01-01

Since 2009, the imiquimod- or Aldara-induced (3M Pharmaceuticals, St. Paul, MN) model of acute skin inflammation has become the most widely used mouse model in preclinical psoriasis studies. Although this model offers researchers numerous benefits, there are important limitations and possible confounding variables to consider. The imiquimod model requires careful consideration and warrants scrutiny of the data generated by its use. In this perspective, we provide an overview of the advantages and disadvantages of this mouse model and offer suggestions for its use in psoriasis research. PMID:27955901

Shifting from Production to Service to Experience-Based Operations

NASA Astrophysics Data System (ADS)

Angelis, Jannis; de Lima, Edson Pinheiro

This chapter covers the shift in focus of value added business operations from ­production to services, and in turn, to experience-based operations where customer involvement itself becomes part of the offering. The shift has significant implications for how businesses are managed. The greater service focus affects the firm's unique value proposition, which necessitates considerations on strategy, supplier relations, post-sale offerings and so on. Meanwhile, the inclusion of customer ­experiences affect the way operations are designed and employed so that these are structurally systematically captured and capitalised.

A Career in Information.

ERIC Educational Resources Information Center

Debons, Anthony; And Others

The best sources of information about educational requirements for careers in information sciences are the institutions that offer training programs in such careers. The American Society for Information Science maintains a file of information on institutions offering training programs in information science. This pamphlet is intended for general…

Enhancement of efficiency in the use of light for cultivation of plants in controlled ecological systems

NASA Technical Reports Server (NTRS)

Mashinsky, A. L.; Oreshkin, V. I.; Nechitailo, G. S.

1994-01-01

The problems of plant cultivation with the use of artificial lighting are related to energetics and, initially, to the lack of effective sources for photosynthesis, secondly to the necessity to supply a system with a considerable power in the form of light energy and to remove transformed thermal energy, and finally to economic considerations. These problems are solved by three ways: by the choice of effective radiation sources, design approaches, and technological methods of cultivation. Here we shall consider the first two ways.

Recent Administrative and Judicial Decisions Regarding Consideration of Source Separation in Determining BACT Under PSD

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Common but unappreciated sources of error in one, two, and multiple-color pyrometry

NASA Technical Reports Server (NTRS)

Spjut, R. Erik

1988-01-01

The most common sources of error in optical pyrometry are examined. They can be classified as either noise and uncertainty errors, stray radiation errors, or speed-of-response errors. Through judicious choice of detectors and optical wavelengths the effect of noise errors can be minimized, but one should strive to determine as many of the system properties as possible. Careful consideration of the optical-collection system can minimize stray radiation errors. Careful consideration must also be given to the slowest elements in a pyrometer when measuring rapid phenomena.

Applications of TIMS data in agricultural areas and related atmospheric considerations

NASA Technical Reports Server (NTRS)

Pelletier, R. E.; Ochoa, M. C.

1986-01-01

While much of traditional remote sensing in agricultural research was limited to the visible and reflective infrared, advances in thermal infrared remote sensing technology are adding a dimension to digital image analysis of agricultural areas. The Thermal Infrared Multispectral Scanner (TIMS) an airborne sensor having six bands over the nominal 8.2 to 12.2 m range, offers the ability to calculate land surface emissivities unlike most previous singular broadband sensors. Preliminary findings on the utility of the TIMS for several agricultural applications and related atmospheric considerations are discussed.

The uses of synchrotron radiation sources for elemental and chemical microanalysis

USGS Publications Warehouse

Chen, J.R.; Chao, E.C.T.; Minkin, J.A.; Back, J.M.; Jones, K.W.; Rivers, M.L.; Sutton, S.R.

1990-01-01

Synchrotron radiation sources offer important features for the analysis of a material. Among these features is the ability to determine both the elemental composition of the material and the chemical state of its elements. For microscopic analysis synchrotron X-ray fluorescence (SXRF) microprobes now offer spatial resolutions of 10 ??m with minimum detection limits in the 1-10 ppm range depending on the nature of the sample and the synchrotron source used. This paper describes the properties of synchrotron radiation and their importance for elemental analysis, existing synchrotron facilities and those under construction that are optimum for SXRF microanalysis, and a number of applications including the high energy excitation of the K lines of heavy elements, microtomography, and XANES and EXAFS spectroscopies. ?? 1990.

Accessibility Considerations for Hybrid Courses

ERIC Educational Resources Information Center

Behling, Kirsten

2017-01-01

This chapter explores the central questions and issues that faculty and administrators need to consider when designing and implementing hybrid courses to ensure that all students, including those with disabilities, have equal access. The author offers resources on faculty development programs, accessibility checklists, and online resources on…

Ethical Issues Involving Research Conducted with Homebound Older Adults

ERIC Educational Resources Information Center

Locher, Julie L.; Bronstein, Janet; Robinson, Caroline O.; Williams, Charlotte; Ritchie, Christine S.

2006-01-01

Conducting research in the home setting with homebound older adults presents distinct ethical and practical challenges that require special consideration. This article describes the methodological issues that make studying homebound older adults especially vulnerable to therapeutic misconception and researcher role conflict and offers practical…

Desktop Design for ESOL Teachers.

ERIC Educational Resources Information Center

Walker, Susan

The guide for teachers of English as a Second Language offers practical advice on the format and layout of instructional materials they produce using desktop publishing technology. An introductory section discusses important design considerations for producing effective materials. Subsequent sections describe how to: organize ideas; outline the…

A Question of Interface Design: How Do Online Service GUIs Measure Up?

ERIC Educational Resources Information Center

Head, Alison J.

1997-01-01

Describes recent improvements in graphical user interfaces (GUIs) offered by online services. Highlights include design considerations, including computer engineering capabilities and users' abilities; fundamental GUI design principles; user empowerment; visual communication and interaction; and an evaluation of online search interfaces. (LRW)

42 CFR 417.150 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... under group insurance policies or contracts, medical or hospital service agreements, enrollment or subscription contracts, or similar group arrangements, in consideration of premiums or other periodic charges... authorized to act on behalf of an employing entity or a group of employing entities to offer the option of...

Consideration of What May Influence Student Outcomes on Alternate Assessment.

ERIC Educational Resources Information Center

Browder, Diane M.; Fallin, Kathy; Davis, Stephanie; Karvonen, Meagan

2003-01-01

This article describes variables that may influence alternate assessment outcomes for students with disabilities and offers recommendations to enhance student achievement. These variables include technical quality, curriculum access, data collection, instructional effectiveness, risk factors, and resources allocated to instruction. Two of four…

Mobile-Assisted Second Language Learning: Developing a Learner-Centered Framework

ERIC Educational Resources Information Center

Leow, Choy Khim; Yahaya, Wan Ahmad Jaafar Wan; Samsudin, Zarina

2014-01-01

The Mobile Assisted Language Learning concept has offered infinite language learning opportunities since its inception 20 years ago. Second Language Acquisition however embraces a considerably different body of knowledge from first language learning. While technological advances have optimized the psycholinguistic environment for language…

Designing Training Materials for Developing Countries.

ERIC Educational Resources Information Center

Rosenweig, Fred

1984-01-01

Describes four training guides developed by the Water and Sanitation for Health Project for use in rural water supply and sanitation projects in developing countries, explains the development process, offers insights gained from the process, and presents five considerations for designing training in third world countries. (MBR)

Capacity for DNA-barcode based taxonomy in support of Great Lakes biological monitoring

EPA Science Inventory

Enumerating organisms collected via nets and sediment grabs is a mainstay of aquatic ecology. Since morphological taxonomy can require considerable resources and expertise, DNA barcode-based identification of mixed-organism samples offers a valuable tool in support of biological...

Narrowing Your Seating Options.

ERIC Educational Resources Information Center

Vukovic, Vladimir

1998-01-01

Offers guidance on selecting appropriate seating furniture for outdoor facilities, arenas, auditoriums, and lecture rooms. Considerations such as beam mounting systems to facilitate laptop computer and campuswide networking use by students and chair durability and ergonomics are discussed as are tips for choosing a seating remanufacturing company.…

7 CFR 766.105 - Agency consideration of servicing requests.

Code of Federal Regulations, 2010 CFR

2010-01-01

... each eligible borrower who requests servicing: (1) Conservation Contract, if requested; (2) Consolidation and rescheduling or reamortization; (3) Deferral; (4) Writedown; and (5) Current market value... develop a feasible plan; (ii) The borrower will be offered current market value buyout. (2) The borrower's...

Effective Informal Learning: Considerations for the Workplace.

ERIC Educational Resources Information Center

Yannie, Mark

2002-01-01

Offers practical advice for learning more effectively on the job. Highlights include types of communication, including written and verbal; informal learning; a work environment that is conducive to informal learning, including organizational culture, job responsibilities, performance requirements, time and scheduling factors, and career stage;…

Probability from a Socio-Cultural Perspective

ERIC Educational Resources Information Center

Sharma, Sashi

2016-01-01

There exists considerable and rich literature on students' misconceptions about probability; less attention has been paid to the development of students' probabilistic thinking in the classroom. Grounded in an analysis of the literature, this article offers a lesson sequence for developing students' probabilistic understanding. In particular, a…

New Developments in Education for the Seventies.

ERIC Educational Resources Information Center

Spaulding, Seth

Theories relating to proposed improvements in education are discussed. Changes in curricula, contributions of fields such as psychology, and issues currently being debated are given consideration. Innovative models and approaches are proposed, and several interesting speculations are offered related to the future of education. Following the…

Masculinities in Higher Education: Theoretical and Practical Considerations

ERIC Educational Resources Information Center

Laker, Jason A., Ed.; Davis, Tracy, Ed.

2011-01-01

"Masculinities in Higher Education" provides empirical evidence, theoretical support, and developmental interventions for educators working with college men both in and out of the classroom. The critical philosophical perspective of the text challenges the status-quo and offers theoretically sound educational strategies to successfully promote…

The Base 32 Method: An Improved Method for Coding Sibling Constellations.

ERIC Educational Resources Information Center

Perfetti, Lawrence J. Carpenter

1990-01-01

Offers new sibling constellation coding method (Base 32) for genograms using binary and base 32 numbers that saves considerable microcomputer memory. Points out that new method will result in greater ability to store and analyze larger amounts of family data. (Author/CM)

Advanced Fusion Reactors for Space Propulsion and Power Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chapman, John J.

In recent years the methodology proposed for conversion of light elements into energy via fusion has made steady progress. Scientific studies and engineering efforts in advanced fusion systems designs have introduced some new concepts with unique aspects including consideration of Aneutronic fuels. The plant parameters for harnessing aneutronic fusion appear more exigent than those required for the conventional fusion fuel cycle. However aneutronic fusion propulsion plants for Space deployment will ultimately offer the possibility of enhanced performance from nuclear gain as compared to existing ionic engines as well as providing a clean solution to Planetary Protection considerations and requirements. Protonmore » triggered 11Boron fuel (p- 11B) will produce abundant ion kinetic energy for In-Space vectored thrust. Thus energetic alpha particles' exhaust momentum can be used directly to produce high Isp thrust and also offer possibility of power conversion into electricity. p-11B is an advanced fusion plant fuel with well understood reaction kinematics but will require some new conceptual thinking as to the most effective implementation.« less

Starting a business as a nurse consultant: practical considerations.

PubMed

Papp, E M

2000-03-01

Nursing experience translates well to self employment in the occupational and environmental health field. However, nurses must conduct a self assessment to determine whether owning a business is a good fit for their personality and work style. Exploring which services to offer is the next step in starting a business and consists of determining not only which service to offer (e.g., writing policies or protocols, providing clinical services) but also which type of consultation model to use (i.e., purchase of expertise, doctor/client, process consultation). Every business must have a plan. A business plan is essential to starting a business. It solidifies the entrepreneur's focus, lays the foundation for the business, provides a tool for evaluating success, and is a strong tool for soliciting financial support. The name of the business is an important consideration because it is often the first contact the customers have with the occupational health nurse consultant. The name must be descriptive, appropriate, and memorable.

Advanced Fusion Reactors for Space Propulsion and Power Systems

NASA Technical Reports Server (NTRS)

Chapman, John J.

2011-01-01

In recent years the methodology proposed for conversion of light elements into energy via fusion has made steady progress. Scientific studies and engineering efforts in advanced fusion systems designs have introduced some new concepts with unique aspects including consideration of Aneutronic fuels. The plant parameters for harnessing aneutronic fusion appear more exigent than those required for the conventional fusion fuel cycle. However aneutronic fusion propulsion plants for Space deployment will ultimately offer the possibility of enhanced performance from nuclear gain as compared to existing ionic engines as well as providing a clean solution to Planetary Protection considerations and requirements. Proton triggered 11Boron fuel (p- 11B) will produce abundant ion kinetic energy for In-Space vectored thrust. Thus energetic alpha particles "exhaust" momentum can be used directly to produce high ISP thrust and also offer possibility of power conversion into electricity. p- 11B is an advanced fusion plant fuel with well understood reaction kinematics but will require some new conceptual thinking as to the most effective implementation.

Roman Military Medicine and Croatian Archaeological Perspectives.

PubMed

Cesarik, Marijan; Cesarik, Nikola; Duplančić, Darko; Štrmelj, David

2016-09-01

This article offers a general examination of the sources responsible for understanding Roman military medicine, starting with literal and epigraphical sources all the way to archaeological remains consisting of hospitals, the infrastructure of military garrisons and small medical tools. Given that not one of the literary sources does not directly mention the medical personnel within the various military units, epigraphical discoveries widely represent the main source of our knowledge on the subject. On the other hand, the archaeological exploration of military garrisons offers proof of the medical care of Roman soldiers. If at first it appears that Roman military medicine is perfectly obvious and clear, actually this is not the case as many questions remain to be answered and debated. In all this, Croatia has its own archaeological perspective, where notably, one site stands out, which could hold a key role according to the layout of buildings within the garrison including its hospital.

Optical Imaging of Ionizing Radiation from Clinical Sources.

PubMed

Shaffer, Travis M; Drain, Charles Michael; Grimm, Jan

2016-11-01

Nuclear medicine uses ionizing radiation for both in vivo diagnosis and therapy. Ionizing radiation comes from a variety of sources, including x-rays, beam therapy, brachytherapy, and various injected radionuclides. Although PET and SPECT remain clinical mainstays, optical readouts of ionizing radiation offer numerous benefits and complement these standard techniques. Furthermore, for ionizing radiation sources that cannot be imaged using these standard techniques, optical imaging offers a unique imaging alternative. This article reviews optical imaging of both radionuclide- and beam-based ionizing radiation from high-energy photons and charged particles through mechanisms including radioluminescence, Cerenkov luminescence, and scintillation. Therapeutically, these visible photons have been combined with photodynamic therapeutic agents preclinically for increasing therapeutic response at depths difficult to reach with external light sources. Last, new microscopy methods that allow single-cell optical imaging of radionuclides are reviewed. © 2016 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

77 FR 44488 - Method 16C for the Determination of Total Reduced Sulfur Emissions From Stationary Sources

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-30

... Method 16C for the Determination of Total Reduced Sulfur Emissions From Stationary Sources AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: This action promulgates Method 16C for measuring total reduced sulfur (TRS) emissions from stationary sources. Method 16C offers the advantages of...

Light intensity and quality from sole-source light-emitting diodes impact growth, morphology, and nutrient content of Brassica microgreens

USDA-ARS?s Scientific Manuscript database

Multi-layer vertical production systems using sole-source (SS) lighting can be used for microgreen production; however, traditional SS lighting can consume large amounts of electrical energy. Light-emitting diodes (LEDs) offer many advantages over conventional light sources including: high photoelec...

Open Source Library Management Systems: A Multidimensional Evaluation

ERIC Educational Resources Information Center

Balnaves, Edmund

2008-01-01

Open source library management systems have improved steadily in the last five years. They now present a credible option for small to medium libraries and library networks. An approach to their evaluation is proposed that takes account of three additional dimensions that only open source can offer: the developer and support community, the source…

DYNAMICS OF AQUATIC FECAL CONTAMINATION, FECAL SOURCE IDENTIFICATION, AND CORRELATION OF BACTEROIDALES HOST-SPECIFIC MARKERS DETECTION WITH FECAL PATHOGENS

EPA Science Inventory

Fecal pollution impairs the health and productivity of coastal waters and causes human disease. PCR of host-specific 16S rDNA sequences from anaerobic Bacteroidales bacteria offers a promising method of tracking fecal contamination and identifying its source(s). Before Bacteroida...

Open Source Communities in Technical Writing: Local Exigence, Global Extensibility

ERIC Educational Resources Information Center

Conner, Trey; Gresham, Morgan; McCracken, Jill

2011-01-01

By offering open-source software (OSS)-based networks as an affordable technology alternative, we partnered with a nonprofit community organization. In this article, we narrate the client-based experiences of this partnership, highlighting the ways in which OSS and open-source culture (OSC) transformed our students' and our own expectations of…

Antecedents to Reverse Auction Use

DTIC Science & Technology

2006-02-01

sourcing the specific products or services. Comprehension of the effect of sourcing strategy on a sourcing professional’s choice of sourcing media ...of strategic items and services are typically manifested in partnerships, long-term contracts, and strategic alliances . Given the nature of such...technical, service, and social benefits a customer firm receives in exchange for the price it pays for a market offering" (Anderson and Narus 1988

Specification of High Activity Gamma-Ray Sources.

ERIC Educational Resources Information Center

International Commission on Radiation Units and Measurements, Washington, DC.

The report is concerned with making recommendations for the specifications of gamma ray sources, which relate to the quantity of radioactive material and the radiation emitted. Primary consideration is given to sources in teletherapy and to a lesser extent those used in industrial radiography and in irradiation units used in industry and research.…

24 CFR 51.101 - General policy.

Code of Federal Regulations, 2010 CFR

2010-04-01

... ENVIRONMENTAL CRITERIA AND STANDARDS Noise Abatement and Control § 51.101 General policy. (a) It is HUD's..., highways and other sources of high noise. (ii) Applicants shall take into consideration HUD environmental... under 24 CFR part 58 must take into consideration the noise criteria and standards in the environmental...

Continuous flow stable isotope methods for study of δ13C fractionation during halomethane production and degradation

USGS Publications Warehouse

Kalin, Robert M.; Hamilton, John T.G.; Harper, David B.; Miller, Laurence G.; Lamb, Clare; Kennedy, James T.; Downey, Angela; McCauley, Sean; Goldstein, Allen H.

2001-01-01

Gas chromatography/mass spectrometry/isotope ratio mass spectrometry (GC/MS/IRMS) methods for δ13C measurement of the halomethanes CH3Cl, CH3Br, CH3I and methanethiol (CH3SH) during studies of their biological production, biological degradation, and abiotic reactions are presented. Optimisation of gas chromatographic parameters allowed the identification and quantification of CO2, O2, CH3Cl, CH3Br, CH3I and CH3SH from a single sample, and also the concurrent measurement of δ13C for each of the halomethanes and methanethiol. Precision of δ13C measurements for halomethane standards decreased (±0.3, ±0.5 and ±1.3‰) with increasing mass (CH3Cl, CH3Br, CH3I, respectively). Given that carbon isotope effects during biological production, biological degradation and some chemical (abiotic) reactions can be as much as 100‰, stable isotope analysis offers a precise method to study the global sources and sinks of these halogenated compounds that are of considerable importance to our understanding of stratospheric ozone destruction. 

Alloy Corrosion Considerations in Low-Cost, Clean Biomass Cookstoves for the Developing World

DOE PAGES

Brady, Michael P.; Banta, Kelly; Mizia, John; ...

2017-04-01

In nearly 40% of the world cooks on open fires or inefficient biomass-fueled cookstoves. The resulting smoke is a health hazard, contributing to an estimated 4 million premature deaths per year, as well as a major source of black carbon emissions. One solution is the introduction of improved, clean-burning biomass cookstoves. One of the most challenging components is the combustor, which must operate at high temperatures (often ≥ 600 °C) in the presence of highly corrosive species released from biomass fuel combustion, yet be sufficiently low cost to permit widespread adoption. In our present work we report the development ofmore » accelerated corrosion test screening protocols employing highly corrosive salt and water vapor species, specifically designed to evaluate alloys for clean biomass cookstove combustors, and corrosion findings for a range of commercial and developmental alloys. Lastly, a new Fe-Cr-Si base alloy that offers promise for improved corrosion resistance at lower cost than state-of the art FeCrAl and stainless steel alloys is also reported.« less

Design of resolution/power controllable Asynchronous Sigma-Delta Modulator

NASA Astrophysics Data System (ADS)

Deshmukh, Anita Arvind; Deshmukh, Raghvendra B.

2016-12-01

This paper presents the design of a Programmable Asynchronous Modulator (PAM) with field control of resolution and power. A novel variable hysteresis Schmitt Trigger (ST) is used for external programmability. Asynchronous Sigma-Delta Modulator (ASDM) implementation with external control voltages is proposed to supervise the resolution and power. This architecture with reduced circuit complexity considerably improves the earlier realizations by eliminating multiple current sources as well switched capacitor circuits and results in power saving up to 87 %. Proposed PAM design demonstrates an improved SNDR of 115 dB, DR of 96 dB, and power consumption below 280 μW. It illustrates Effective Number of Bits (ENOB) to 18.81 and Figure of Merit (FoM) to 0.15 fJ/conversion step. Modulator is implemented in Cadence UMC Hspice 0.18 μm CMOS analog technology. Off-chip PAM control for resolution/power performance has potential applications in battery operated ultra low power applications like IoT; where ADC is one of the major power consuming components. It offers the promise for an efficient performance with power saving.

Beyond information access: Support for complex cognitive activities in public health informatics tools.

PubMed

Sedig, Kamran; Parsons, Paul; Dittmer, Mark; Ola, Oluwakemi

2012-01-01

Public health professionals work with a variety of information sources to carry out their everyday activities. In recent years, interactive computational tools have become deeply embedded in such activities. Unlike the early days of computational tool use, the potential of tools nowadays is not limited to simply providing access to information; rather, they can act as powerful mediators of human-information discourse, enabling rich interaction with public health information. If public health informatics tools are designed and used properly, they can facilitate, enhance, and support the performance of complex cognitive activities that are essential to public health informatics, such as problem solving, forecasting, sense-making, and planning. However, the effective design and evaluation of public health informatics tools requires an understanding of the cognitive and perceptual issues pertaining to how humans work and think with information to perform such activities. This paper draws on research that has examined some of the relevant issues, including interaction design, complex cognition, and visual representations, to offer some human-centered design and evaluation considerations for public health informatics tools.

The impact of the tax system on health insurance coverage.

PubMed

Gruber, J

2001-01-01

A central question in health economics is the extent to which this tax subsidization matters for the health insurance coverage of the U.S. population. I assess the impact of taxes on health insurance by using the considerable existing variation in tax subsidies, both at a point in time and across time. I do so by putting together data from more than a decade of Current Population Survey (CPS) data sets, and matching to workers in those data sets their tax subsidies to health insurance coverage. I find that the elasticity of insurance eligibility of workers is at least -0.6, and that the elasticity of own insurance coverage is roughly similar; the results imply that most of the impact of taxes on insurance coverage arise through firm offering and eligibility decisions. I also find that higher tax rates induce more private coverage through other sources, but less public coverage, so that overall there is a reduction in the rate of uninsurance that is comparable to the change in own employer-provided insurance coverage.

Moocs - a Force to BE Reckoned with or a Temporary Phenomenon

NASA Astrophysics Data System (ADS)

Koenig, G.

2015-05-01

The digital revolution has dramatically changed our everyday life. Using the Internet has evolved into a key technology that became an indispensable information source. The expansion of Internet usage beyond mere information storage to a learning and communication tool sets new standards for the development of educational concepts. Digital textbooks, multimedia tutorials, elearning offers using learning management systems and massive open online courses (MOOCs) demonstrate the development phases of new strategies for knowledge transfer. Initially starting in the USA MOOC platforms like Udacity, Coursera or edX had gained an enormous media attention caused by the huge number of participants. Initially this new teaching method was welcomed euphorically; the didactic preparation of courses is however viewed with scepticism, particularly in Europe. This paper will review the status of MOOCs, with a particular emphasis on Photogrammetry, Remote Sensing, and Geomatics. A selection of these 'Geo-MOOCs' will be presented. The consideration of these free online learning resources will include a commentary on quality and perceived effectiveness. Finally it will be outlined if MOOCs are reasonable and promising in our fields.

Multi-fuel driven Janus micromotors.

PubMed

Gao, Wei; D'Agostino, Mattia; Garcia-Gradilla, Victor; Orozco, Jahir; Wang, Joseph

2013-02-11

Here the first example of a chemically powered micromotor that harvests its energy from the reactions of three different fuels is presented. The new Al/Pd Janus microspheres-prepared by depositing a Pd layer on one side of Al microparticles-are propelled efficiently by the thrust of hydrogen bubbles generated from different reactions of Al in strong acidic and alkaline environments, and by an oxygen bubble thrust produced at their partial Pd coating in hydrogen peroxide media. High speeds and long lifetimes of 200 μm s(-1) and 8 min are achieved in strong alkaline media and acidic media, respectively. The ability to autonomously adapt to the presence of a new fuel (surrounding environment), without compromising the propulsion behavior is illustrated. These data also represent the first example of a chemically powered micromotor that propels autonomously and efficiently in alkaline environments (pH > 11) without additional fuels. The ability to use multiple fuel sources to power the same micromotor offers a broader scope of operation and considerable promise for diverse applications of micromotors in different chemical environments. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

[German national second-opinion network for testicular cancer and penile carcinoma : Two sources for evidence-based information].

PubMed

Schrader, M; Zengerling, F; Hakenberg, O W; Protzel, C

2016-09-01

The second-opinion network for testicular cancer is an internet-based platform addressing physicians treating testicular cancer patients. They are offered a second-opinion before determining further therapy after orchiectomy and completion of staging. The high rate of discrepancies between the first and second opinion in more than 30 % supports the assumption of a deficit in the implementation of treatment guidelines. In 2015, approximately 22 % of the newly diagnosed cases with testicular cancer in Germany were covered by this system. According to the present interim analysis, the second-opinion platform helps to avoid overtreatment of testicular cancer patients. The high acceptance of the project and the encouraging results of this interim analysis gave rise to considerations to apply the second-opinion model to penile carcinoma. Data from the UK and the Netherlands show that the second-opinion network for penile cancer could help to improve treatment standards and results in Germany. Current data and the intended further development of the system are discussed.

A reticle retrofit and dosimetric consideration for a linear accelerator.

PubMed

Krithivas, V

1996-01-01

An imperfect reticle system in an accelerator causes uncertainties in source-skin distance (SSD), off-axis distance (OAD), isocenter, and so forth. A reticle was designed and fabricated, and its implications on x-ray and electron beam dosimetry were investigated. A new reticle frame was dimensioned to fit snugly in the accelerator. The frame was fabricated to carry a pair of adjustable cross wires and to allow the machine operation in the photon and electron modes. The impact of the cross wires on 6 MV photon and 5-10 MeV electron beam parameters such as dose rate (Gy/monitor unit), beam uniformity, surface dose, and so forth, were studied using suitable ion chambers and phantoms. The retrofitted system offered long-term mechanical stability leading to precise SSD, OAD, and isocenter measurements. Changes introduced by the cross wires on the 6 MV photon and 5-10 MeV electron beams are presented. Long-term stability of a reticle in an accelerator is important for an accurate patient setup and for making reliable dosimetric measurements. Beam characteristrics have to be studied whenever modifications on a reticle system are made.

Biochar, compost and biochar-compost blend as options to recover nutrients and sequester carbon.

PubMed

Oldfield, Thomas L; Sikirica, Nataša; Mondini, Claudio; López, Guadalupe; Kuikman, Peter J; Holden, Nicholas M

2018-07-15

This work assessed the potential environmental impact of recycling organic materials in agriculture via pyrolysis (biochar) and composting (compost), as well its combination (biochar-compost blend) versus business-as-usual represented by mineral fertiliser. Life cycle assessment methodology was applied using data sourced from experiments (FP7 project Fertiplus) in three countries (Spain, Italy and Belgium), and considering three environmental impact categories, (i) global warming; (ii) acidification and (iii) eutrophication. The novelty of this analysis is the inclusion of the biochar-compost blend with a focus on multiple European countries, and the inclusion of the acidification and eutrophication impact categories. Biochar, compost and biochar-compost blend all resulted in lower environmental impacts than mineral fertiliser from a systems perspective. Regional differences were found between biochar, compost and biochar-compost blend. The biochar-compost blend offered benefits related to available nutrients and sequestered C. It also produced yields of similar magnitude to mineral fertiliser, which makes its acceptance by farmers more likely whilst reducing environmental impacts. However, careful consideration of feedstock is required. Copyright © 2018 Elsevier Ltd. All rights reserved.

Making the Case for Laws That Improve Health: A Framework for Public Health Law Research

PubMed Central

Burris, Scott; Wagenaar, Alexander C; Swanson, Jeffrey; Ibrahim, Jennifer K; Wood, Jennifer; Mello, Michelle M

2010-01-01

Context: Public health law has received considerable attention in recent years and has become an essential field in public health. Public health law research, however, has received less attention. Methods: Expert commentary. Findings: This article explores public health law research, defined as the scientific study of the relation of law and legal practices to population health. The article offers a logic model of public health law research and a typology of approaches to studying the effects of law on public health. Research on the content and prevalence of public health laws, processes of adopting and implementing laws, and the extent to which and mechanisms through which law affects health outcomes can use methods drawn from epidemiology, economics, sociology, and other disciplines. The maturation of public health law research as a field depends on methodological rigor, adequate research funding, access to appropriate data sources, and policymakers’ use of research findings. Conclusions: Public health law research is a young field but holds great promise for supporting evidence-based policymaking that will improve population health. PMID:20579282

A survey on computer aided diagnosis for ocular diseases

PubMed Central

2014-01-01

Background Computer Aided Diagnosis (CAD), which can automate the detection process for ocular diseases, has attracted extensive attention from clinicians and researchers alike. It not only alleviates the burden on the clinicians by providing objective opinion with valuable insights, but also offers early detection and easy access for patients. Method We review ocular CAD methodologies for various data types. For each data type, we investigate the databases and the algorithms to detect different ocular diseases. Their advantages and shortcomings are analyzed and discussed. Result We have studied three types of data (i.e., clinical, genetic and imaging) that have been commonly used in existing methods for CAD. The recent developments in methods used in CAD of ocular diseases (such as Diabetic Retinopathy, Glaucoma, Age-related Macular Degeneration and Pathological Myopia) are investigated and summarized comprehensively. Conclusion While CAD for ocular diseases has shown considerable progress over the past years, the clinical importance of fully automatic CAD systems which are able to embed clinical knowledge and integrate heterogeneous data sources still show great potential for future breakthrough. PMID:25175552

Current-voltage characteristics of molecular conductors: two versus three terminal

NASA Astrophysics Data System (ADS)

Damle, P.; Rakshit, T.; Paulsson, M.; Datta, S.

2002-09-01

This paper addresses the question of whether a ``rigid molecule'' (one which does not deform in an external field) used as the conducting channel in a standard three-terminal MOSFET configuration can offer any performance advantage relative to a standard silicon MOSFET. A self-consistent solution of coupled quantum transport and Poisson's equations shows that even for extremely small channel lengths (about 1 nm), a ``well-tempered'' molecular FET demands much the same electrostatic considerations as a ``well-tempered'' conventional MOSFET. In other words, we show that just as in a conventional MOSFET, the gate oxide thickness needs to be much smaller than the channel length (length of the molecule) for the gate control to be effective. Furthermore, we show that a rigid molecule with metallic source and drain contacts has a temperature independent subthreshold slope much larger than 60 mV/decade, because the metal-induced gap states in the channel prevent it from turning off abruptly. However, this disadvantage can be overcome by using semiconductor contacts because of their band-limited nature.

[Localization of perforators in the lower leg by digital antomy imaging methods].

PubMed

Wei, Peng; Ma, Liang-Liang; Fang, Ye-Dong; Xia, Wei-Zhi; Ding, Mao-Chao; Mei, Jin

2012-03-01

To offer both the accurate three-dimensional anatomical information and algorithmic morphology of perforators in the lower leg for perforator flaps design. The cadaver was injected with a modified lead oxide-gelatin mixture. Radiography was first performed and the images were analyzed using the software Photoshop and Scion Image. Then spiral CT scan was also performed and 3-dimensional images were reconstructed with MIMICS 10.01 software. There are (27 +/- 4) perforators whose outer diameter > or = 0.5 mm ( average, 0.8 +/- 0.2 mm). The average pedicle length within the superficial fascia is (37.3 +/- 18.6) mm. The average supplied area of each perforator is (49.5 +/- 25.5) cm2. The three-dimensional model displayed accurate morphology structure and three-dimensional distribution of the perforator-to- perforator and perforator-to-source artery. The 3D reconstruction model can clearly show the geometric, local details and three-dimensional distribution. It is a considerable method for the study of morphological characteristics of the individual perforators in human calf and preoperative planning of the perforator flap.

Multi-Center Biologic Assignment Trial Comparing Reduced Intensity Allogeneic Hematopoietic Cell Transplant to Hypomethylating Therapy or Best Supportive Care in Patients Aged 50-75 with Intermediate-2 and High Risk Myelodysplastic Syndrome Blood and Marrow Transplant Clinical Trials Network #1102 Study Rationale, Design and Methods

PubMed Central

Saber, Wael; Le Rademacher, Jennifer; Sekeres, Mikkael; Logan, Brent; Lewis, Moira; Mendizabal, Adam; Leifer, Eric; Appelbaum, Frederick R.; Horowitz, Mary M; Nakamura, Ryotaro; Cutler, Corey S.

2014-01-01

The introduction of reduced intensity conditioning regimens (RIC) made it possible to offer allogeneic hematopoietic cell transplantation (alloHCT) to older patients with myelodysplastic syndromes (MDS). However, the relative risks and benefits of alloHCT compared to novel non-transplant therapies continue to be the source of considerable uncertainty. We will perform a prospective biologic assignment trial to compare RIC alloHCT to non-transplant therapies based on donor availability. Primary outcome is 3-year overall survival. Secondary outcomes include leukemia-free survival, quality of life, and cost-effectiveness. Four hundred patients will be enrolled over roughly 3 years. Planned subgroup analyses will evaluate key biologic questions, such as the impact of age & response to hypomethylating agents on treatment effects. Findings from this study potentially may set a new standard of care for older MDS patients who are considered candidates for alloHCT. PMID:24972249

Relationship between ionospheric plasma bubble occurrence and lightning strikes over the Amazon region

NASA Astrophysics Data System (ADS)

Sousasantos, Jonas; Sobral, José Humberto Andrade; Alam Kherani, Esfhan; Magalhães Fares Saba, Marcelo; Rodolfo de Campos, Diovane

2018-03-01

The vertical coupling between the troposphere and the ionosphere presents some remarkable features. Under intense tropospheric convection, gravity waves may be generated, and once they reach the ionosphere, these waves may seed instabilities and spread F and equatorial plasma bubble events may take place. Additionally, there is a close association between severe tropospheric convection and lightning strikes. In this work an investigation covering an equinox period (September-October) during the deep solar minimum (2009) presents the relation between lightning strike activity and spread F (equatorial plasma bubble) detected over a low-latitude Brazilian region. The results show a considerable correlation between these two phenomena. The common element in the center of this conformity seems to be the gravity waves. Once gravity waves and lightning strikes share the same source (intense tropospheric convection) and the effects of such gravity waves in the ionosphere include the seeding of instabilities according to the gravity waves magnitude, the monitoring of the lightning strike activity seems to offer some information about the subsequent development of spread F over the equatorial region.

Practical wavelength calibration considerations for UV-visible Fourier-transform spectroscopy.

PubMed

Salit, M L; Travis, J C; Winchester, M R

1996-06-01

The intrinsic wavelength scale in a modern reference laser-controlled Michelson interferometer-sometimes referred to as the Connes advantage-offers excellent wavelength accuracy with relative ease. Truly superb wavelength accuracy, with total relative uncertainty in line position of the order of several parts in 10(8), should be within reach with single-point, multiplicative calibration. The need for correction of the wavelength scale arises from two practical effects: the use of a finite aperture, from which off-axis rays propagate through the interferometer, and imperfect geometric alignment of the sample beam with the reference beam and the optical axis of the moving mirror. Although an analytical correction can be made for the finite-aperture effect, calibration with a trusted wavelength standard is typically used to accomplish both corrections. Practical aspects of accurate calibration of an interferometer in the UV-visible region are discussed. Critical issues regarding accurate use of a standard external to the sample source and the evaluation and selection of an appropriate standard are addressed. Anomalous results for two different potential wavelength standards measured by Fabry-Perot interferometry (Ar II and (198)Hg I) are observed.

Alloy Corrosion Considerations in Low-Cost, Clean Biomass Cookstoves for the Developing World

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brady, Michael P.; Banta, Kelly; Mizia, John

In nearly 40% of the world cooks on open fires or inefficient biomass-fueled cookstoves. The resulting smoke is a health hazard, contributing to an estimated 4 million premature deaths per year, as well as a major source of black carbon emissions. One solution is the introduction of improved, clean-burning biomass cookstoves. One of the most challenging components is the combustor, which must operate at high temperatures (often ≥ 600 °C) in the presence of highly corrosive species released from biomass fuel combustion, yet be sufficiently low cost to permit widespread adoption. In our present work we report the development ofmore » accelerated corrosion test screening protocols employing highly corrosive salt and water vapor species, specifically designed to evaluate alloys for clean biomass cookstove combustors, and corrosion findings for a range of commercial and developmental alloys. Lastly, a new Fe-Cr-Si base alloy that offers promise for improved corrosion resistance at lower cost than state-of the art FeCrAl and stainless steel alloys is also reported.« less

Evaluation of Ti-Zr-V (NEG) Thin Films for their pumping speed and pumping Capacity

NASA Astrophysics Data System (ADS)

Bansod, Tripti; Sindal, B. K.; Kumar, K. V. A. N. P. S.; Shukla, S. K.

2012-11-01

Deposition of NEG thin films onto the interior walls of the vacuum chambers is an advanced technique to convert a vacuum chamber from a gas source to an effective pump. These films offer considerably large pumping speed for reactive gases like CO, H2 etc. A UHV compatible pumping speed measurement system was developed in-house to measure the pumping speed of NEG coated chambers. To inject the fixed quantity of CO and H2 gas in pumping speed measurement set-up a calibrated leak was also developed. Stainless steel chambers were sputter coated with thin film of Ti-Zr-V getter material using varied parameters for different compositions and thickness. Pumping capacity which is a function of sorbed gas quantities was also studied at various activation temperatures. In order to optimize the activation temperature for maximum pumping speed for CO and H2, pumping speeds were measured at room temperature after activation at different temperatures. The experimental system detail, pumping performance of the NEG film at various activation temperatures and RGA analysis are presented.

Sources of funding for Nobel Prize-winning work: public or private?

PubMed

Tatsioni, Athina; Vavva, Effie; Ioannidis, John P A

2010-05-01

Funding is important for scientists' work and may contribute to exceptional research outcomes. We analyzed the funding sources reported in the landmark scientific papers of Nobel Prize winners. Between 2000 and 2008, 70 Nobel laureates won recognition in medicine, physics, and chemistry. Sixty five (70%) of the 93 selected papers related to the Nobel-awarded work reported some funding source including U.S. government sources in 53 (82%), non-U.S. government sources in 19 (29%), and nongovernment sources in 33 (51%). A substantial portion of this exceptional work was unfunded. We contacted Nobel laureates whose landmark papers reported no funding. Thirteen Nobel laureates responded and offered their insights about the funding process and difficulties inherent in funding. Overall, very diverse sources amounting to a total of 64 different listed sponsors supported Nobel-related work. A few public institutions, in particular the U.S. National Institutes of Health (with n=26 funded papers) and the National Science Foundation (with n=17 papers), stood out for their successful record for funding exceptional research. However, Nobel-level work arose even from completely unfunded research, especially when institutions offered a protected environment for dedicated scientists.

Comparative pathogenesis and characterization of contemporary 1-7-4 PRRSV isolates in weanling age piglets

USDA-ARS?s Scientific Manuscript database

Porcine respiratory and reproductive syndrome (PRRS) continues to be an economically important disease affecting commercial pig production in the United States and worldwide. Its considerable sequence and antigenic variation, coupled with the limited protection offered by current vaccine options im...

Furthering Higher Education Possibilities through Massive Open Online Courses

ERIC Educational Resources Information Center

Mesquita, Anabela, Ed.; Peres, Paula, Ed.

2015-01-01

In recent years, technological advancements have enabled higher-learning institutions to offer millions of independent learners the opportunity to participate in open-access online courses. As this practice expands, drawing considerable media attention, questions continue to arise regarding pedagogical methodology and the long-term viability of…

Sexual Harassment Victims: Psycholegal and Family Therapy Considerations.

ERIC Educational Resources Information Center

Woody, Robert Henley; Perry, Nancy Walker

1993-01-01

Examines legal proscriptions and practical definitions of sexual harassment, describes psychological effects of sexual harassment (Sexual Harassment Trauma Syndrome) for victim-client and impact on family system, and offers guidance for family therapy. Focuses on vulnerability of victim-client, reconstruction of self-concept as primary goal of…

Metabolite profiling of fish skin mucus: a novel approach for minimally-invasive environmental exposure monitoring and surveillance

EPA Science Inventory

The application of 'omics tools to biologically based monitoring and surveillance of aquatic environments shows considerable promise for complementing chemical monitoring in ecological risk assessments. However, few of the current approaches offer the ability to sample ecological...

Donor Behavior and Voluntary Support for Higher Education Institutions.

ERIC Educational Resources Information Center

Leslie, Larry L.; Ramey, Garey

Voluntary support of higher education in America is investigated through regression analysis of institutional characteristics at two points in time. The assumption of donor rationality together with explicit consideration of interorganizational relationships offers a coherent framework for the analysis of voluntary support by the major…

EDUCATIONAL TECHNOLOGY, PREPARATION AND USE IN ADULT BASIC EDUCATION PROGRAMS.

ERIC Educational Resources Information Center

IVERSON, MAURICE T.; AND OTHERS

AUDIOVISUAL MATERIALS, WHEN COMBINED WITH CONSIDERATION OF THE WAYS PEOPLE LEARN, CAN OFFER NEW WAYS OF EXPRESSING IDEAS, PRESENTING INFORMATION, AND MAKING INSTRUCTION CHALLENGING AND EFFICIENT. THIS PUBLICATION, DIRECTED AT TEACHERS OF ADULT BASIC EDUCATION AND THEIR ADMINISTRATORS, ILLUSTRATES APPLICATIONS OF INSTRUCTIONAL TECHNOLOGY TO ADULT…

Self-Psychology, Shame, and Adolescent Suicide: Theoretical and Practical Considerations.

ERIC Educational Resources Information Center

Shreve, Barry W.; Kunkel, Mark A.

1991-01-01

Discusses role of shame in adolescent suicidal behaviors using psychoanalytic self-psychology of Heinz Kohut as theoretical foundation. Describes shame as central component of suicidal behavior within context of adolescence. Offers theoretical explanation of adolescent suicidal behavior from self-psychology perspective. Presents suggestions for…

Choosing a CD-ROM Encyclopedia: How to Critically Evaluate the Product.

ERIC Educational Resources Information Center

Dickinson, Gail

1990-01-01

Offers criteria for the critical evaluation of CD-ROM encyclopedias. Differences between CD-ROM and print encyclopedias are discussed; search strategies are explained; evaluation criteria are suggested, including help messages, screen format, indexing method, and graphics and print options; future considerations are suggested, including…

Recruitment and Screening of Minors for Group Counseling.

ERIC Educational Resources Information Center

Ritchie, Martin H.; Huss, Susan Norris

2000-01-01

Group counseling with minors requires special considerations in the recruitment and screening process. Suggestions are offered to ensure that potential members are not labeled during recruitment. Discusses characteristics for screening as well as contraindications for group counseling with children and adolescents. Also discusses ethical and legal…

Infusing Outdoor Field Experiences into the Secondary Biology Curriculum.

ERIC Educational Resources Information Center

Owens, Ginny

1984-01-01

To offer students biological field experiences, teachers should use their own basic skills, be enthusiastic motivators, participate in community programs/courses/workshops to acquire additional skills/knowledge for outdoor biological education, plan outdoor excursions with safety considerations in mind, and use available resources for classroom…

Suggested Perspectives in Counseling the American Indian Client.

ERIC Educational Resources Information Center

Paisano-Suazo, Aleta

The standard western theoretical approach to mental health counseling is not applicable to the views held by Native American clients. Consideration must be given to their unique differences, if the therapist is to provide maximum effectiveness. Several perspectives offer alternative counseling procedures. For instance, Indians place great…

Creating University-Community Alliances to Build Internship Programs

ERIC Educational Resources Information Center

Perfect, Michelle M.; Schmitt, Ara J.; Hughes, Tammy L.; Herndon-Sobalvarro, Adrianna

2015-01-01

By bringing together a community of field-based practitioners, university faculty can help school districts develop accredited school psychology internships. This article describes the rationale for an increase in university involvement in the development of internships, offers considerations unique to schools when supporting the development of an…

Instructional Television Facilities: A Planning Guide.

ERIC Educational Resources Information Center

Witherspoon, John P.; Kessler, William J.

When planning an instructional television (ITV) system, it is suggested that educational objectives should outweigh technological considerations and that expert advice be secured before the planning process is far advanced. In line with the latter suggestion, the book offers a background of technical knowledge aimed at educational administrators…

A heuristic for landscape management

Treesearch

Martín Alfonso B. Mendoza; Jesús S. Zepeta; Juan José A. Fajardo

2006-01-01

The development of landscape ecology has stressed out the importance of spatial and sequential relationships as explanations to forest stand dynamics, and for other natural ambiences. This presentation offers a specific design that introduces spatial considerations into forest planning with the idea of regulating fragmentation and connectivity in commercial forest...

Towards a Theory of Rural Development.

ERIC Educational Resources Information Center

Haque, Wahidul; And Others

Historical developments in rural India, Bangladesh, Sri Lanka, and China are the empirical basis of this study which offers a theory of rural development for all Asia keyed to fundamental humanistic values rather than narrower techno-economic considerations. Previous efforts have often been "top-down" processes tending to serve…

Investigating the Use of Text Messages in Mobile Learning

ERIC Educational Resources Information Center

Geng, Gretchen

2013-01-01

Nowadays, teaching and learning have been shifted from traditional classrooms to technology-supported learning environment. By offering a convenient, efficient and financially affordable information technology learning environment, mobile learning is a topic that is of considerable interest for education audiences owing to the pervasive nature of…

What Does a Cultural Approach Offer to Research on Learning?

ERIC Educational Resources Information Center

Hatano, Giyoo; Miyake, Naomi

1991-01-01

The articles of this issue argue that taking culture into consideration in research on learning can enhance understanding of a variety of phenomena related to learning. Discussion reinforces this position and further considers learning processes that are or are not determined by culture. (SLD)

MS Is a Family Affair. Revised Edition.

ERIC Educational Resources Information Center

Braunel, Laura M.; And Others

The booklet offers practical suggestions to teach the person with multiple sclerosis to conserve energy and maintain a balance between rest and activity. The discussion centers around personal hygiene, homemaking activities, family relationships, and hobbies. Another section gives tips for getting around in the community, with considerations for…

Student Portfolios 101

ERIC Educational Resources Information Center

Lippert, Robert

2004-01-01

Student portfolios can offer great benefits to both high school and postsecondary education programs. They assist instructors in determining the progress of a student's performance and provide students with a vital self-promotion tool for job searches or the higher education application process. This brief article describes a few considerations to…

Strategies for satellite-based monitoring of CO2 from distributed area and point sources

NASA Astrophysics Data System (ADS)

Schwandner, Florian M.; Miller, Charles E.; Duren, Riley M.; Natraj, Vijay; Eldering, Annmarie; Gunson, Michael R.; Crisp, David

2014-05-01

Atmospheric CO2 budgets are controlled by the strengths, as well as the spatial and temporal variabilities of CO2 sources and sinks. Natural CO2 sources and sinks are dominated by the vast areas of the oceans and the terrestrial biosphere. In contrast, anthropogenic and geogenic CO2 sources are dominated by distributed area and point sources, which may constitute as much as 70% of anthropogenic (e.g., Duren & Miller, 2012), and over 80% of geogenic emissions (Burton et al., 2013). Comprehensive assessments of CO2 budgets necessitate robust and highly accurate satellite remote sensing strategies that address the competing and often conflicting requirements for sampling over disparate space and time scales. Spatial variability: The spatial distribution of anthropogenic sources is dominated by patterns of production, storage, transport and use. In contrast, geogenic variability is almost entirely controlled by endogenic geological processes, except where surface gas permeability is modulated by soil moisture. Satellite remote sensing solutions will thus have to vary greatly in spatial coverage and resolution to address distributed area sources and point sources alike. Temporal variability: While biogenic sources are dominated by diurnal and seasonal patterns, anthropogenic sources fluctuate over a greater variety of time scales from diurnal, weekly and seasonal cycles, driven by both economic and climatic factors. Geogenic sources typically vary in time scales of days to months (geogenic sources sensu stricto are not fossil fuels but volcanoes, hydrothermal and metamorphic sources). Current ground-based monitoring networks for anthropogenic and geogenic sources record data on minute- to weekly temporal scales. Satellite remote sensing solutions would have to capture temporal variability through revisit frequency or point-and-stare strategies. Space-based remote sensing offers the potential of global coverage by a single sensor. However, no single combination of orbit and sensor provides the full range of temporal sampling needed to characterize distributed area and point source emissions. For instance, point source emission patterns will vary with source strength, wind speed and direction. Because wind speed, direction and other environmental factors change rapidly, short term variabilities should be sampled. For detailed target selection and pointing verification, important lessons have already been learned and strategies devised during JAXA's GOSAT mission (Schwandner et al, 2013). The fact that competing spatial and temporal requirements drive satellite remote sensing sampling strategies dictates a systematic, multi-factor consideration of potential solutions. Factors to consider include vista, revisit frequency, integration times, spatial resolution, and spatial coverage. No single satellite-based remote sensing solution can address this problem for all scales. It is therefore of paramount importance for the international community to develop and maintain a constellation of atmospheric CO2 monitoring satellites that complement each other in their temporal and spatial observation capabilities: Polar sun-synchronous orbits (fixed local solar time, no diurnal information) with agile pointing allow global sampling of known distributed area and point sources like megacities, power plants and volcanoes with daily to weekly temporal revisits and moderate to high spatial resolution. Extensive targeting of distributed area and point sources comes at the expense of reduced mapping or spatial coverage, and the important contextual information that comes with large-scale contiguous spatial sampling. Polar sun-synchronous orbits with push-broom swath-mapping but limited pointing agility may allow mapping of individual source plumes and their spatial variability, but will depend on fortuitous environmental conditions during the observing period. These solutions typically have longer times between revisits, limiting their ability to resolve temporal variations. Geostationary and non-sun-synchronous low-Earth-orbits (precessing local solar time, diurnal information possible) with agile pointing have the potential to provide, comprehensive mapping of distributed area sources such as megacities with longer stare times and multiple revisits per day, at the expense of global access and spatial coverage. An ad hoc CO2 remote sensing constellation is emerging. NASA's OCO-2 satellite (launch July 2014) joins JAXA's GOSAT satellite in orbit. These will be followed by GOSAT-2 and NASA's OCO-3 on the International Space Station as early as 2017. Additional polar orbiting satellites (e.g., CarbonSat, under consideration at ESA) and geostationary platforms may also become available. However, the individual assets have been designed with independent science goals and requirements, and limited consideration of coordinated observing strategies. Every effort must be made to maximize the science return from this constellation. We discuss the opportunities to exploit the complementary spatial and temporal coverage provided by these assets as well as the crucial gaps in the capabilities of this constellation. References Burton, M.R., Sawyer, G.M., and Granieri, D. (2013). Deep carbon emissions from volcanoes. Rev. Mineral. Geochem. 75: 323-354. Duren, R.M., Miller, C.E. (2012). Measuring the carbon emissions of megacities. Nature Climate Change 2, 560-562. Schwandner, F.M., Oda, T., Duren, R., Carn, S.A., Maksyutov, S., Crisp, D., Miller, C.E. (2013). Scientific Opportunities from Target-Mode Capabilities of GOSAT-2. NASA Jet Propulsion Laboratory, California Institute of Technology, Pasadena CA, White Paper, 6p., March 2013.

Cultivating a Cross-Cultural Disposition

DTIC Science & Technology

2007-06-15

OF ADAPTATION PROCESS ........................................................................................70 REFERENCE LIST...and the use of distance learning media echo recommendations offered by one of the article’s cited military sources, retired Major General Robert H...leaving one to his or her personal definition. Those that do offer conceptualization of culture often equate it to group level cognitive processes , an

Personal travel assistants and the world wide web

DOT National Transportation Integrated Search

1997-01-01

To be successful, handheld computers known as Personal Travel Assistants (PTAs) must be connected to external information sources. The viability of using the Internet and the world wide web (www) as such sources is explored. Considerations include wh...

PCDD/F EMISSIONS FROM UNCONTROLLED, DOMESTIC WASTE BURNING

EPA Science Inventory

Considerable uncertainty exists in the inventory of polychlorinated dibenzodioxin and dibenzofuran (PCDD/F) emissions from controlled combustion sources such as backyard burning of domestic waste. The contribution from these sources to the worldwide PCDD/F balance may be signific...

Deep ultraviolet semiconductor light sources for sensing and security

NASA Astrophysics Data System (ADS)

Shatalov, Max; Bilenko, Yuri; Yang, Jinwei; Gaska, Remis

2009-09-01

III-Nitride based deep ultraviolet (DUV) light emitting diodes (LEDs) rapidly penetrate into sensing market owing to several advantages over traditional UV sources (i.e. mercury, xenon and deuterium lamps). Small size, a wide choice of peak emission wavelengths, lower power consumption and reduced cost offer flexibility to system integrators. Short emission wavelength offer advantages for gas detection and optical sensing systems based on UV induced fluorescence. Large modulation bandwidth for these devices makes them attractive for frequency-domain spectroscopy. We will review present status of DUV LED technology and discuss recent advances in short wavelength emitters and high power LED lamps.

Black cherry provenances for planting in northwestern Pennsylvania

Treesearch

Russell S. Walters; Russell S. Walters

1985-01-01

After 14 years, survival of 8 of 25 planted black cherry sources is greater than 70 percent, and there are no significant differences in height. These sources offer the greater potential for planting in northwestern Pennsylvania; they include four Pennsylvania sources plus one each from Tennessee, West Virginia, Ohio, and Virginia. Planted trees did not grow better...

Los Angeles OneSource System Youth Participant Customer Satisfaction Survey, 2010-2011

ERIC Educational Resources Information Center

Heisley, Deborah D.; Moore, Richard W.; Patch, Robin N.

2012-01-01

As part of the Workforce Investment Act of 1998, Los Angeles OneSource Centers offer low-income youth ages 14-21 services aimed at improving educational achievement, enhancing job skills, and preparing for college. The primary purpose of this study was to evaluate the youths' satisfaction with services received at 14 OneSource Centers throughout…

Distortions and Disconnections: Disrupted Brain Connectivity in Autism

ERIC Educational Resources Information Center

Wass, Sam

2011-01-01

The past few years have seen considerable interest in findings of abnormal brain connectivity in the autism spectrum disorders (ASD). We review recent work from neuroimaging and other sources, and argue that there is considerable convergent evidence suggesting that connectivity is disrupted in ASD. We point to evidence both of local…

Nanocrystalline cellulose from coir fiber: preparation, properties, and applications

USDA-ARS?s Scientific Manuscript database

Nanocrystalline cellulose derived from various botanical sources offers unique and potentially useful characteristics. In principle, any cellulosic material can be considered as a potential source of a nanocrystalline material, including crops, crop residues, and agroindustrial wastes. Because of t...

The Significance of Stance: An Invitation to Aesthetic Response.

ERIC Educational Resources Information Center

Molinelli, Paul M.

This essay explores the concept of reader stance as defined by L. Rosenblatt (1978, 1994) as a useful framework from which to view the relative imbalance between the efferent and aesthetic reading of literature, particularly among schoolage adolescents. It then examines how 4 theoretical models and perspectives offer considerable explanatory…

29 CFR 101.7 - Settlements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 2 2010-07-01 2010-07-01 false Settlements. 101.7 Section 101.7 Labor Regulations Relating... Section 10 (a) to (i) of the Act and Telegraph Merger Act Cases § 101.7 Settlements. Before any complaint... for the submission and consideration of facts, argument, offers of settlement, or proposals of...

The Role of Geriatric Assessment Units in Caring for the Elderly: An Analytic Review.

ERIC Educational Resources Information Center

Rubenstein, Laurence Z.; And Others

1982-01-01

Although their structures and objectives vary considerably Geriatric Assessment Units (GAUs) are generally designed to assess elderly patients' medical and psychosocial problems, to determine optimal placement, and often to provide therapy and rehabilitation. Offers a framework for examining structural and outcome variables for GAUs. (Author)

Touring Can Be Hazardous to Your Health: Staying Healthy on the Road.

ERIC Educational Resources Information Center

Suggs, Del

1998-01-01

The health needs and challenges of performers who travel from campus to campus are examined, and recommendations are offered for promoting better health through good sleep, good nutrition, exercise, and using medications. Considerations concerning health insurance and maintaining spiritual and emotional health are also discussed. Actions that…

Colorizing Educational Research: African American Life and Schooling as an Exemplar

ERIC Educational Resources Information Center

Monroe, Carla R.

2013-01-01

Although previous authors have offered persuasive arguments about the salience of race in the scholastic enterprise, colorism remains a relatively underexplored concept. This article augments considerations of social forces by exploring how color classifications within racial arrangements frame pathways for communities of color and, therefore,…

Teacher Retirement Benefits

ERIC Educational Resources Information Center

Costrell, Robert; Podgursky, Michael

2009-01-01

The ongoing global financial crisis is forcing many employers, from General Motors to local general stores, to take a hard look at the costs of the compensation packages they offer employees. For public school systems, this will entail a consideration of fringe benefit costs, which in recent years have become an increasingly important component of…

Diversity, Inequality, and a Post-Structural Politics for Education

ERIC Educational Resources Information Center

Youdell, Deborah

2006-01-01

This paper considers the contribution to understanding educational inequalities offered by post-structural theories of power and the subject. The paper locates this consideration in the context of the ongoing endeavour in education studies to make sense of, and identify ways of interrupting, abiding educational exclusions and inequalities. The…

Sexual Harassment in the Law Enforcement Workplace.

ERIC Educational Resources Information Center

Irons, Nicholas H.

Considerable confusion exists over male/female relationships in the work place, especially in such male-dominated professions as law enforcement. The laws governing sexual harassment offer unclear guidelines regarding the definition of harm that results from such harassment. This paper addresses the special problems of sexual harassment in the…

Climate projections FAQ

Treesearch

A.E. Daniels; J.F. Morrison; L.A. Joyce; N.L. Crookston; S.C. Chen; S.G. McNulty

2012-01-01

Climate scenarios offer one way to identify and examine the land management challenges posed by climate change. Selecting projections, however, requires careful consideration of the natural resources under study, and where and how they are sensitive to climate. Selection also depends on the robustness of different projections for the resources and geographic area of...

Commentary--Enlarging Concepts, Refining Methods, Improving Interventions

ERIC Educational Resources Information Center

Palacios, Jesús

2015-01-01

As illustrated by the articles in this special issue, the research into ethnic identity in adoption is making significant progress. At the same time, it faces new challenges in the definition of concepts, the use of appropriate methods of study, and the consideration of implications for professional interventions. This commentary offers additional…

Possible influences on clinical supervision.

PubMed

Jones, A

This article discusses clinical supervision and suggests that, aside from helping nurses to enhance their clinical effectiveness, it could offer experiential methods of assisting nurses to identify and locate supportive networks in the workplace. The advantages and difficulties of supervision relationships are described in context, including some consideration of authority and control.

48 CFR 215.203-70 - Requests for proposals-tiered evaluation of offers.

Code of Federal Regulations, 2010 CFR

2010-10-01

... ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY... shall be consistent with FAR part 19. (b) Consideration shall be given to the tiers of small businesses (e.g., 8(a), HUBZone small business, service-disabled veteran-owned small business, small business...

Carbon Offsets | Climate Neutral Research Campuses | NREL

Science.gov Websites

offsets may fit into climate action plans for your research campus. Options Considerations Sample Project United States. Instead, several organizations offer certification, so the buyer must carefully research a seller's claims for carbon reduction. Today, carbon offsets are widely available. For example, the Chicago

The "Body Domestic" and the "Body Politic": Education and Advocacy.

ERIC Educational Resources Information Center

Thompson, Patricia J.

This paper offers a new consideration of the "body domestic" and the "body politic" in educational issues. It proposes that these entities be developed as complementary, rather than oppositional, theoretical categories to explain the historical development of, and contemporary issues in, family and consumer sciences (home…

47 CFR 25.158 - Consideration of GSO-like satellite applications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... directional antennas. Examples of GSO-like satellite systems are those which use earth stations with antennas... contiguous bandwidth in both the uplink and downlink band. Each licensee's bandwidth selection shall not... selection. (e) Services offered pursuant to a GSO-like license in a frequency band granted before the...

ECS Law & Education Center Footnotes. No. 3.

ERIC Educational Resources Information Center

Education Commission of the States, Denver, CO. Law and Education Center.

Commentary and advice in four legal areas are offered in this newsletter on educational law. First, the document outlines preventive legal review for public educators in four basic steps, including anticipation of legal challenges, evaluation of the challenges' legal merits, consideration of the policy issues raised by potential challenges, and…

An Evaluation of an Automated Approach to Concept-Based Grammar Instruction

ERIC Educational Resources Information Center

Lyddon, Paul A.

2012-01-01

Acquiring sufficient linguistic proficiency to perform competently in academic and professional contexts generally requires substantial study time beyond what most language programs can offer in the classroom. As such, teachers and students alike would benefit considerably from high quality self-access materials promoting independent learning out…

The Electronic Portfolio: Ethical Considerations

ERIC Educational Resources Information Center

McFadden, Joan R.; Saiki, Diana

2005-01-01

Computer technology has become important in Family and Consumer Science (FCS) because it offers improved communication with capabilities such as the Internet that allows for a "more productive workplace" (Jones, 2003, p. 38). Kittross and Gordon (2003) alerted users that as computer technology evolves, there is a need for colleges and universities…

Strategic Renewal and Development Implications of Organisational Effectiveness Research in Higher Education in Australia.

ERIC Educational Resources Information Center

Lysons, Art

1999-01-01

Suggests that organizational effectiveness research has made considerable progress in empirically deriving a systematic framework of theoretical and practical utility in Australian higher education. Offers a taxonomy based on the competing values framework and discusses use of inter-organizational comparisons and profiles for diagnosis in…

Volunteer Community Language Bank.

ERIC Educational Resources Information Center

Novak, Sigfrid S.; And Others

Lake Charles, Louisiana established a language bank capable of providing interpreters for 20 foreign languages. All participants are volunteers who offer to help free of charge in case of emergencies arising because of the considerable numbers of foreign visitors in the area. Smooth operation of the language bank depends on the following: (1) an…

Playgrounds for Infants, Toddlers, and Preschoolers.

ERIC Educational Resources Information Center

Frost, Joe L.; Dempsey, James D.

This paper offers practical assistance for the development of high quality playgrounds for infants, toddlers, and preschoolers in child care. Discussion of the value of play in child development and the benefits of outdoor play is followed by a consideration of the ways children use playgrounds in exercise, construction, group and dramatic forms…

The Practical Considerations of Opening School Facilities to Lifelong Learning.

ERIC Educational Resources Information Center

Odell, John H.

1997-01-01

There are many reasons why a school should plan for extending its facilities' hours of use and making them available to the community. Benefits include improving cost effectiveness in using limited resources, improving security, promoting the school, enhancing staff's potential to offer industry-related training and expertise, and enriching…

Spaces of Rupture: Wondering, Wandering, Remixing

ERIC Educational Resources Information Center

Benedict, Cathy

2017-01-01

This response is based on my presentation at Teachers College, Columbia University celebrating the launch of Allsup's (2016) book, "Remixing the Classroom: Toward an Open Philosophy of Music Education." I enter the text with openness, and with a willingness to ponder and consider. As such I offer the following considerations for further…

Asian American Acculturation and Enculturation: Construct Clarification and Measurement Consolidation

ERIC Educational Resources Information Center

Zhang, Shengying; Moradi, Bonnie

2013-01-01

An overview of the evolution of Asian American acculturation and enculturation theory and measurement is offered, focusing on major theoretical advancements and methodological issues that are salient for measuring these constructs. Informed by these considerations, an empirical approach is taken to clarifying the dimensions of Asian American…

Spreadsheet Applications: Prototyping an Innovative Blended Course

ERIC Educational Resources Information Center

Baker, J. Howard

2004-01-01

After teaching the advanced spreadsheet course at a major university in Louisiana as a traditional classroom course for a number of years, it was decided to create a prototype-blended course, with a considerable portion offered via distance education. This research, which uses a prototyping methodology, is exploratory in nature. Prototyping can…

Postsecondary Distance Education in Mexico and Worldwide: Issues and Considerations

ERIC Educational Resources Information Center

Becerra, Bertha Leticia Gonzalez; Almendra, Manuel Pio Rosales; Flores, Jose Daniel Corona

2012-01-01

Postsecondary distance education has attracted increasing attention in recent years, an understandable change when one considers that innovative approaches to distance education have offered opportunities to overcome some of the key challenges in traditional "brick and mortar" education. Nonetheless, there are a plethora of issues that…

Considerations in Counseling the Retiring Career Officer for Reemployment

ERIC Educational Resources Information Center

Schlenoff, David

1977-01-01

In this article, the unique characteristics of the retiring career officer are discussed, and specific problems encountered by counselors assisting the career officer in his or her transition from the military to civilian work environment are noted. Suggestions are offered concerning counseling such persons for reemployment. (Author)

The LMS Selection Process: Practices and Considerations. ECAR Research Bulletin

ERIC Educational Resources Information Center

Cavanagh, Thomas B.

2014-01-01

With more than 80% of institutions offering online learning options and even more using web technologies to enhance traditional classroom instruction, the learning management system (LMS) is increasingly an indispensable, enterprise-level technology for today's colleges and universities. Naturally, each institution has a unique set of…

Jury Selection in Child Sex Abuse Trials: A Case Analysis

ERIC Educational Resources Information Center

Cramer, Robert J.; Adams, Desiree D.; Brodsky, Stanley L.

2009-01-01

Child sex abuse cases have been the target of considerable psycho-legal research. The present paper offers an analysis of psychological constructs for jury selection in child sex abuse cases from the defense perspective. The authors specifically delineate general and case-specific jury selection variables. General variables include…

77 FR 29257 - Registration of Copyright: Definition of Claimant

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-17

... considerable legal uncertainty while offering no clear benefits to the registration system. Removing it will... individuals or entities that have obtained the contractual right to claim legal title to copyright in an... author, the contractual right to claim legal title to the copyright in an application for copyright...

Complexities of Racial Identity Development for Asian Pacific Islander Desi American (APIDA) College Students

ERIC Educational Resources Information Center

Chan, Jason

2017-01-01

Higher education research increasingly acknowledges the multiple identities and communities within the Asian Pacific Islander Desi American (APIDA) student population. This chapter explores the complex and multifaceted aspects of APIDA students and offers key considerations for student affairs practitioners working with today's APIDA student…

Chinese Students' Approach to Learning English: Psycholinguistic and Sociolinguistic Perspectives.

ERIC Educational Resources Information Center

He, Hongwei

A study examined the historical, cultural, social, pedagogical, and psychological factors affecting Chinese students' language learning styles and attitudes, particularly concerning learning English as a Second Language (ESL). The first section offers an overview of considerations in understanding the cultural background that students bring to the…

Something's Underfoot.

ERIC Educational Resources Information Center

Morrow, Hugh

1997-01-01

Examines the decision-making factors when selecting school flooring. Areas to consider include what the area being covered is used for and the flooring's life-cycle costing. Suggestions on the types of flooring to consider are offered, as are tips on buying flooring made of recycled materials, and considerations for making the best overall…

Maximize Benefits, Minimize Risk: Selecting the Right HVAC Firm.

ERIC Educational Resources Information Center

Golden, James T.

1993-01-01

An informal survey of 20 major urban school districts found that 40% were currently operating in a "break down" maintenance mode. A majority, 57.9%, also indicated they saw considerable benefits in contracting for heating, ventilating, and air conditioning (HVAC) maintenance services with outside firms. Offers guidelines in selecting…

Design Considerations for Enhancing Confidence and Participation in Web Based Courses.

ERIC Educational Resources Information Center

Winfield, William; Mealy, Martha; Scheibel, Pamela

The University of Wisconsin Learning Innovations Center's instructional design model for World Wide Web delivered courses incorporates a range of collaborative discussions and interactive experiences for the learner. In addition, these courses capitalize on the multimedia learning environment that the web offers to accommodate many kinds of…

Things that Keep Us up at Night

ERIC Educational Resources Information Center

Fitzpatrick, Kristen MacCartney; Walker, Willis C.

2006-01-01

In this article, the authors share their experiences as librarians, and offer their perspectives on issues critical to the new academic librarian. When the authors sat down to sort through ideas for this article, it became apparent that while their backgrounds, coursework, and experiences differed considerably, their passions and concerns are more…

Biological rhythms and rotating shift work : some considerations for air traffic controllers and managers.

DOT National Transportation Integrated Search

1986-01-01

This report is a general review of some of the current themes and practices regarding rotating shift work; to inform air traffic controllers, technicians, and managers of these issues; and to offer some ideas that may be helpful in dealing with diffi...

Sighting Horizons of Teaching in Higher Education

ERIC Educational Resources Information Center

Barnett, Ronald; Guzmán-Valenzuela, Carolina

2017-01-01

This conceptual paper tackles the matter of teaching in higher education and proposes a concept of "horizons of teaching." It firstly offers an overview of the considerable empirical literature around teaching--especially conceptions of teaching, approaches to teaching and teaching practices--and goes on to pose some philosophical and…

Planning Responses to Demographic Change. AIR 1986 Annual Forum Paper.

ERIC Educational Resources Information Center

Taylor, Bryan J. R.; Taylor, Elizabeth A.

A method for forecasting the number of college graduates in the United Kingdom is described, and suggestions are offered about ways that society should react to influence declining enrollments and potential reductions in technologically skilled graduates. Consideration is given to the implications of recruiting noncollege-bound individuals to…

Teaching English to Arabic-Speaking Students: Cultural and Linguistic Considerations.

ERIC Educational Resources Information Center

Santos, Sheryl L.; Suleiman, Mahmoud F.

Cultural and linguistic information useful to teachers of native Arabic-speakers in English as a Second Language (ESL) and bilingual education is offered. This includes background information on geographic, political, religious, and ethnic divisions, stereotypes commonly held by Arabs about Americans and American society, common stereotypes about…

Studies of two cumulative effects riddles

Treesearch

R. M. Rice; R. R. Ziemer; J. Lewis; T. E. Lisle

1989-01-01

Although it is unquestionably prudent to consider the cumulative watershed effects (CWEs) of timber harvesting, the presumed CWE phenomena offer limited opportunity for scientific inquiry. We are addressing two questions: are there synergistic sedimentation effects of sufficient magnitude to warrant consideration beyond efforts to reduce on-site erosion; and what are...

24 CFR 983.51 - Owner proposal selection procedures.

Code of Federal Regulations, 2013 CFR

2013-04-01

... operated to provide broad public notice of the opportunity to offer PBV proposals for consideration by the... general circulation and other means designed and actually operated to provide broad public notice. The... operated to provide broad public notice. (e) PHA-owned units. A PHA-owned unit may be assisted under the...

Multiple Drafts of Experimental Laboratory Reports.

ERIC Educational Resources Information Center

Sanford, James F.

Students could gain considerable insight into the philosophy and methods of scientific experimentation if instructors adopted procedures based on an understanding of and respect for writing as a process. Laboratory courses in psychology offer such an opportunity. These courses usually involve a heavy workload for both students and faculty, for, in…

Hostile Work Environment: What Communication Administrators and Educators Can Learn from Communication-based Law.

ERIC Educational Resources Information Center

Newburger, Craig

2001-01-01

Presents a consideration of sexual harassment laws that are intended to underscore the variety of heuristic possibilities offered by inquiry into communication-based laws, for both communication administrators and educators. Concludes that communication administration, communication education, and evolving communication-based legal standards and…

Supporting Student Veterans in Transition

ERIC Educational Resources Information Center

Rumann, Corey B.; Hamrick, Florence A.

2009-01-01

The purpose of this chapter is to offer frameworks and considerations for student affairs professionals seeking to serve the transition needs of the current generation of student veterans. The historical intersections of the military and higher education, particularly with respect to the effects of the draft on students and higher education,…

Discourses of Cultural Relevance in Nunavut Schooling

ERIC Educational Resources Information Center

Aylward, M. Lynn

2007-01-01

Academic discourse relating to the cultural relevance of indigenous education is ever expanding both nationally in Canada and internationally. Reflecting upon recent research data as well as lived experience as a teacher educator in Nunavut, I offer a critique of some well-established beliefs connected to considerations of culturally appropriate…

Web-Based Training in Corporations: Organizational Considerations

ERIC Educational Resources Information Center

Chamers, Terri; Lee, Doris

2004-01-01

Advances in technology offer the possibility of new methods for delivering instruction. Learning via the Internet is being heralded by many as the new pedagogical model for training. Recent issues of training, computer, and management magazines all suggest that web-based training (WBT) is the best way to reach geographically dispersed employees…

Childhood Gender Identity...Disorder? Developmental, Cultural, and Diagnostic Concerns

ERIC Educational Resources Information Center

Dragowski, Eliza A.; Scharron-del Rio, Maria R.; Sandigorsky, Amy L.

2011-01-01

Childhood gender identity development is reviewed in the context of biological, environmental, cultural, and diagnostic factors. With the upcoming 5th revision of the "Diagnostic and Statistical Manual of Mental Disorders," the authors offer a critical consideration of childhood gender identity disorder, along with proposed diagnostic changes.…

Seeding techniques for sagebrush community restoration after fire

Treesearch

Jeffrey E. Ott; Anne Halford; Nancy Shaw

2016-01-01

Purpose: To outline important considerations and options for post-fire seeding, including the selection of seed mixes and seeding equipment for restoring sagebrush communities following fire. The emphasis is on lower-elevation communities where restoration needs are greatest. References and resources are offered for greater detail and guidance on specific...

Higher Education, Adult Learning, and Greening of the Economy

ERIC Educational Resources Information Center

Koester, Robert J.

2013-01-01

As formal learning communities, colleges and universities can readily integrate social, economic, and environmental considerations in day-to-day operational practices and curricular offerings. Moreover, a college or university can work with, and model for, the local community, implementing ideas that then can be adopted by the surrounding…