Science.gov

Sample records for space probes implications

  1. Space Probe Launch

    NASA Technical Reports Server (NTRS)

    1970-01-01

    Managed by Marshall Space Flight Center, the Space Tug was a reusable multipurpose space vehicle designed to transport payloads to different orbital inclinations. Utilizing mission-specific combinations of its three primary modules (crew, propulsion, and cargo) and a variety of supplementary kits, the Space Tug was capable of numerous space applications. This 1970 artist's concept depicts the Tug's propulsion module launching a space probe into lunar orbit.

  2. A Computational Analysis of Galactic Exploration with Space Probes - Implications for the Fermi Paradox

    NASA Astrophysics Data System (ADS)

    Cotta, C.; Morales, A.

    Temporal explanations to the Fermi paradox state that the vast scale of the galaxy diminishes the chances of establishing contact with an extraterrestrial technological civilization (ETC) within a certain time window. This argument is tackled in this work in the context of exploration probes, whose propagation can be faster than that of a colonization wavefront. Extensive computational simulations have been done to build a numerical model of the dynamics of the exploration. A probabilistic analysis is subsequently conducted in order to obtain bounds on the number of ETCs that may be exploring the galaxy without establishing contact with Earth, depending on factors such as the number of probes they use, their lifetime and whether they leave some long-term imprint on explored systems or not. The results indicate that it is unlikely that more than ~102-103 ETCs are exploring the galaxy in a given Myr, if their probes have a lifetime of 50 Myr and contact evidence lasts for 1 Myr. This bound goes down to ~10 if contact evidence lasts for 100 Myr, and is also shown to be inversely proportional to the lifetime of probes. These results are interpreted in light of the Fermi paradox and are compatible with non-stationary astrobiological models in which a few ETCs have gradually appeared in the Fermi-Hart timescale.

  3. Gravity Probe B Space Vehicle

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The space vehicle for Gravity Probe B (GP-B) arrives at the launch site at Vandenburg Air Force Base. GP-B is the relativity experiment being developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Scheduled for launch in 2003 and managed for NASA by the Marshall Space Flight Center, development of the GP-B is the responsibility of Stanford University, with major subcontractor Lockheed Martin Corporation.

  4. The navigation of space probes

    NASA Technical Reports Server (NTRS)

    Fliegel, H. F.; Ohandley, D. A.; Zielenbach, J. W.

    1974-01-01

    A new navigational method combining electronic measurement procedures and celestial mechanics makes it possible to conduct a space probe very close to a desired point in the neighborhood of a remote planet. Approaches for the determination of the position of the space probe in space are discussed, giving attention to the effects of errors in the employed data. The application of the navigational methods in a number of space missions is also considered.

  5. Active probing of space plasmas

    NASA Astrophysics Data System (ADS)

    Chan, Chang; Silevitch, Michael B.; Villalon, Elena

    1989-09-01

    During the course of the research period our efforts were focused on the following areas: (1) An examination of stochastic acceleration mechanisms in the ionosphere; (2) A study of nonequilibrium dynamics of the coupled magnetosphere - ionosphere system; and (3) Laboratory studies of active space experiments. Reprints include: Dynamics of charged particles in the near wake of a very negatively charged body -- Laboratory experiment and numerical simulation; Laboratory study of the electron temperature in the near wake of a conducting body; New model for auroral breakup during substorms; Substorm breakup on closed field lines; New model for substorm on sets -- The pre-breakup and triggering regimes; Model of the westward traveling surge and the generation of Pi 2 pulsations; Ionospheric electron acceleration by electromagnetic waves near regions of plasma resonances; Relativistic particle acceleration by obliquely propagating electromagnetic fields; Some consequences of intense electromagnetic wave injection into space plasmas.

  6. Probing planetary pollution from space

    NASA Technical Reports Server (NTRS)

    Fishman, Jack

    1991-01-01

    The data sets obtained from instruments that have measured carbon monoxide and tropospheric ozone from space are reviewed. These instruments include a gas cell correlation radiometer named MAPS (Measurement of Air Pollution from Satellites), the Total Ozone Mapping Spectrometer, and the Stratospheric Aerosol and Gas Experiment. Particular attention is given to differential absorption lidar technology which can determine the vertical distribution of aerosols and selected trace gases with considerably more resolution than passive remote sensing techniques. The current plans for monitoring pollution from spaceborne platforms are also discussed.

  7. Space Probes Program Status Report

    NASA Technical Reports Server (NTRS)

    1959-01-01

    Brief of Progress: A. Preparations for the 26 November launching of ABLE-4 ATLAS are proceeding as scheduled, with no problems apparent at this time. Many of the electrical tests and subsystems checks have been completed. Minor modifications have been made to the solar paddle tie-down and release mechanism, after an extensive testing program; B. Work toward the 10 December launching of ABLE-4 THOR is also progressing on schedule. Subsystem checks have been started, and mechanical fit checks have been completed; C. During the month of October, a total of 136 tests were performed on components and assemblies related to the ABLE program. These included acceptance tests, type tests, R&D tests, etc. Of this total, only three failures occurred, all of which have been corrected; D. The Space Physics Data Library, Los Angeles, California, is now in operation. Data reduction gear in the Library is in breadboard operation with completion of the installation expected by mid-November. Analysis of ABLE-3 data is progressing satisfactorily at the Library.

  8. Encounter with Jupiter. [Pioneer 10 space probe

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Pioneer 10 space probe's encounter with the Jupiter is discussed in detail. Tables are presented which include data on the distances during the encounter, times of crossing satellite orbits, important events in the flight near Jupiter, and time of experiments. Educational study projects are also included.

  9. Compression of Space for Low Visibility Probes

    PubMed Central

    Born, Sabine; Krüger, Hannah M.; Zimmermann, Eckart; Cavanagh, Patrick

    2016-01-01

    Stimuli briefly flashed just before a saccade are perceived closer to the saccade target, a phenomenon known as perisaccadic compression of space (Ross et al., 1997). More recently, we have demonstrated that brief probes are attracted towards a visual reference when followed by a mask, even in the absence of saccades (Zimmermann et al., 2014a). Here, we ask whether spatial compression depends on the transient disruptions of the visual input stream caused by either a mask or a saccade. Both of these degrade the probe visibility but we show that low probe visibility alone causes compression in the absence of any disruption. In a first experiment, we varied the regions of the screen covered by a transient mask, including areas where no stimulus was presented and a condition without masking. In all conditions, we adjusted probe contrast to make the probe equally hard to detect. Compression effects were found in all conditions. To obtain compression without a mask, the probe had to be presented at much lower contrasts than with masking. Comparing mislocalizations at different probe detection rates across masking, saccades and low contrast conditions without mask or saccade, Experiment 2 confirmed this observation and showed a strong influence of probe contrast on compression. Finally, in Experiment 3, we found that compression decreased as probe duration increased both for masks and saccades although here we did find some evidence that factors other than simply visibility as we measured it contribute to compression. Our experiments suggest that compression reflects how the visual system localizes weak targets in the context of highly visible stimuli. PMID:27013989

  10. Compression of Space for Low Visibility Probes.

    PubMed

    Born, Sabine; Krüger, Hannah M; Zimmermann, Eckart; Cavanagh, Patrick

    2016-01-01

    Stimuli briefly flashed just before a saccade are perceived closer to the saccade target, a phenomenon known as perisaccadic compression of space (Ross et al., 1997). More recently, we have demonstrated that brief probes are attracted towards a visual reference when followed by a mask, even in the absence of saccades (Zimmermann et al., 2014a). Here, we ask whether spatial compression depends on the transient disruptions of the visual input stream caused by either a mask or a saccade. Both of these degrade the probe visibility but we show that low probe visibility alone causes compression in the absence of any disruption. In a first experiment, we varied the regions of the screen covered by a transient mask, including areas where no stimulus was presented and a condition without masking. In all conditions, we adjusted probe contrast to make the probe equally hard to detect. Compression effects were found in all conditions. To obtain compression without a mask, the probe had to be presented at much lower contrasts than with masking. Comparing mislocalizations at different probe detection rates across masking, saccades and low contrast conditions without mask or saccade, Experiment 2 confirmed this observation and showed a strong influence of probe contrast on compression. Finally, in Experiment 3, we found that compression decreased as probe duration increased both for masks and saccades although here we did find some evidence that factors other than simply visibility as we measured it contribute to compression. Our experiments suggest that compression reflects how the visual system localizes weak targets in the context of highly visible stimuli.

  11. Exploring the Galaxy using space probes

    NASA Astrophysics Data System (ADS)

    Bjørk, R.

    2007-04-01

    This paper investigates the possible use of space probes to explore the Milky Way, as a means both of finding life elsewhere in the Galaxy and as finding an answer to the Fermi paradox. Exploration of the Galaxy is simulated by first examining how long time it takes a given number of space probes to explore 40000 stars in a box from -300 to 300 pc above the Galactic thin disc, as a function of Galactic radius. The Galaxy is then modelled to consist of 260000 of these 40000 stellar systems all located in a defined Galactic Habitable Zone and how long a time it takes to explore this zone is shown. The result is that with eight probes, each with eight subprobes, 4% of the Galaxy can be explored in 2.92x10^8 years. Increasing the number of probes to 200, still with eight subprobes each, reduces the exploration time to 1.52x10^7 years.

  12. Galileo Space Probe News Conference. Part 1

    NASA Technical Reports Server (NTRS)

    1996-01-01

    This NASA Kennedy Space Center (KSC) video release presents Part 1 of a press conference regarding the successful entry of the Galileo Space Probe into Jupiter's atmosphere. The press conference panel is comprised of twelve principal investigators and project scientists that oversee the Galileo mission. Among these panelists, William J. O'Neil (Jet Propulsion Lab.) begins the video praising all of the scientists that worked on the orbiter mission. He then presents a visual overview of Galileo's overall mission trajectory and schedule. Marcie Smith (NASA Ames Research Center) then describes the Galileo Probe mission and the overall engineering and data acquisition aspects of the Probe's Jupiter atmospheric entry. Dr. Richard Young (NASA Ames Research Center) follows with a brief scientific overview, describing the measurements of the atmospheric composition as well as the instruments that were used to gather the data. Atmospheric pressure, temperature, density, and radiation levels of Jupiter were among the most important parameters measured. It is explained that these measurements would be helpful in determining among other things, the overall dynamic meteorology of Jupiter. A question and answer period follows the individual presentations. Atmospheric thermal structure, water abundances, wind profiles, radiation, cloud structure, chemical composition, and electricity are among the topics discussed. Parts 2 and 3 of the press conference can be found in document numbers NONP-NASA-VT-2000001074, and NONP-NASA-VT-2000001075.

  13. Employment of Asteroids for Movement Space Ship and Probes

    NASA Technical Reports Server (NTRS)

    Bolonkin, Alexander

    2002-01-01

    At present, rockets are used to change the trajectory of space ships and probes. This method is very expensive and requires a lot of fuel, which limits the feasibility of space stations, interplanetary space ships, and probes. Sometimes space probes use the gravity field of a planet. However, there are only 9 planets in our solar system and they are separated by great distances. There are tens of millions of asteroids in outer space. The author offers a revolutionary method for changing the trajectory of space probes. This method uses the kinetic or rotary energy of asteroids, meteorites or other space bodies (small planets, natural planet satellites, etc.). to increase (to decrease) ship (probe) speed up to 1000 m/sec (or more) and to get any new direction in outer space. The flight possibilities of space ships and probes are increased by a factor of millions.

  14. Probing Stellar Dynamics With Space Photometry

    NASA Astrophysics Data System (ADS)

    García, Rafael A.; Salabert, D.; Ballot, J.; Beck, P. G.; Bigot, L.; Corsaro, E.; Creevey, O.; Egeland, R.; Jiménez, A.; Mathur, S.; Metcalfe, T.; do Nascimento, J.; Pallé, P. L.; Pérez Hernández, F.; Regulo, C.

    2016-08-01

    The surface magnetic field has substantial influence on various stellar properties that can be probed through various techniques. With the advent of new space-borne facilities such as CoRoT and Kepler, uninterrupted long high-precision photometry is available for hundred of thousand of stars. This number will substantially grow through the forthcoming TESS and PLATO missions. The unique Kepler observations -covering up to 4 years with a 30-min cadence- allows studying stellar variability with different origins such as pulsations, convection, surface rotation, or magnetism at several time scales from hours to years. We study the photospheric magnetic activity of solar-like stars by means of the variability induced in the observed signal by starspots crossing the visible disk. We constructed a solar photometric magnetic activity proxy, Sph from SPM/VIRGO/SoHO, as if the Sun was a distant star and we compare it with several solar well-known magnetic proxies. The results validate this approach. Thus, we compute the Sph proxy for a set of CoRoT and Kepler solar-like stars for which pulsations were already detected. After characterizing the rotation and the magnetic properties of 300 solar-like stars, we use their seismic properties to characterize 18 solar analogs for which we study their magnetism. This allows us to put the Sun into context of its siblings.

  15. Huygens space probe ready to leave Europe

    NASA Astrophysics Data System (ADS)

    1997-03-01

    Over the past year, the Huygens probe has been integrated and extensively tested at the facilities of Daimler Benz Aerospace Dornier Satellitensysteme in Ottobrunn near Munich. It was designed and developed for ESA by a European industrial consortium led by Aerospatiale (F) as prime contractor. The European activities have been successfully completed and this is to be formalised by the Flight Acceptance Review which will release the probe for shipment to the USA. To mark this important milestone a press briefing is scheduled for Wednesday, 26 March at 10.00 hours at Daimler-Benz Aerospace Dornier Satellitensysteme in Ottobrunn. The detailed programme of the press briefing is attached. If you wish to attend the press briefing, please complete the attached accreditation form and return it, preferably by fax, to : Daimler Benz Aerospace Dornier Satellitensysteme Mr. Mathias Pikelj, Fax. + 49 7545 8 5589, Tel. + 49 7545 8 9123 NOTE FOR THE EDITORS: Background facts about the Cassini Huygens mission Huygens is a medium-sized mission of ESA's Horizons 2000 programme for space science, and a contribution to the joint NASA ESA Cassini mission. Christiaan Huygens discovered Saturn s moon Titan in 1655, and the mission named after him aims to land a 343 kilogram probe on Titan carrying a package of scientific instruments through the atmosphere. Six sets of instruments will analyse the chemical composition of the atmosphere, observe the weather and topography of Titan, and examine the nature of its surface. Titan is larger than the planet Mercury, and its unique atmosphere, rich in nitrogen and hydrocarbons, may resemble the atmosphere of the primitive Earth, before life began. Nominal dates for the Huygens mission are as follows: * launch, 6 October 1997 * arrival at Saturn, 1 July 2004 * release of Huygens, 6 November 2004 * entry into Titan's atmosphere, 27 November 2004. The Saturn Orbiter, the other element in the Cassini mission, will relay the signals from Huygens to

  16. Space Station - Implications for space manufacturing

    NASA Technical Reports Server (NTRS)

    Tingey, D. L.; Willenberg, H. J.; Atkins, H. L.

    1985-01-01

    Space-based materials processing R&D is examined. It is proposed that the Space Station's Microgravity and Materials Processing Facility will be utilized by academic, government, and commercial customers. Users requirements for materials processing in space are discussed. Consideration is given to the time allocation of the facility, charges to users, and the property rights of the users.

  17. Space Exploration; Power Sources for Deep Space Probes

    DTIC Science & Technology

    1998-05-01

    are Europa Orbiter, Pluto Express, Solar Probe, Interstellar Probe, Europa Lander, Io Volcanic Observer, Titan Organic Explorer, and Neptune Orbiter...example, the new nuclear-fueled generator that NASA studied for use on the Pluto Express spacecraft is projected to need less than 10 pounds of

  18. Future studies of planetary rings by space probes

    NASA Technical Reports Server (NTRS)

    Stone, E. C.

    1984-01-01

    Recent space probe observations of the rings of Jupiter and Saturn have furnished a substantial enhancement of the current understanding of the outer planets' rings. Voyager 2 offers further opportunities for the study of the Neptune and Uranus ring systems. The Galileo mission to Jupiter furnishes the first opportunity for long term space probe studies of a planetary ring system. It is suggested that an appropriately instrumented Saturn orbiter would not only provide a similar opportunity for the study of the Saturn rings, but may also be the only means by which to adequately address the nature of the diverse phenomena displayed by this prototypical planetary ring system.

  19. Space-charge limits of ion sensitive probes

    NASA Astrophysics Data System (ADS)

    Brunner, D.; LaBombard, B.; Ochoukov, R.; Sullivan, R.; Whyte, D.

    2013-12-01

    Ion sensitive probes (ISPs) are used to measure ion temperature and plasma potential in magnetized plasmas. Their operation relies on the difference in electron and ion Larmor radii to preferentially collect the ion species on a recessed electrode. Because of their simple two-electrode construction and optimal geometry for heat flux handling they are an attractive probe to use in the high heat flux boundary of magnetic confinement fusion experiments. However, the integrity of its measurements is rarely, if ever, checked under such conditions. Recent measurements with an ISP in the Alcator C-Mod tokamak have shown that its ion current is space-charge limited and thus its current-voltage (I-V) response does not contain information on the ion temperature. We numerically solve a 1D Vlasov-Poisson model of ion collection to determine how much bias is needed to overcome space-charge effects and regain the classic I-V characteristic with an exponential decay. Prompted by the observations of space charge in C-Mod, we have performed a survey of ISP measurements reported in the literature. Evidence of space-charge limited current collection is found on many probes, with few authors noting its presence. Some probes are able to apparently exceed the classic 1D space-charge limit because electrons can E × B drift into the probe volume, partially reducing the net ion charge; it is argued that this does not, however, change the basic problem that space charge compromises the measurement of ion temperature. Guidance is given for design of ISPs to minimize the effects of space charge.

  20. Mission to Jupiter. [Pioneer 10 and 11 space probes

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The Pioneer 10 and Pioneer 11 space probes and their missions to Jupiter are discussed along with the experiments and investigations which will be conducted onboard. Jupiter's atmosphere, its magnetic fields, radiation belts, the spacecraft instruments, and the Jovian system will be investigated. Educational study projects are also included.

  1. The Evolving Space Weather System—Van Allen Probes Contribution

    NASA Astrophysics Data System (ADS)

    Zanetti, L. J.; Mauk, B. H.; Fox, N. J.; Barnes, R. J.; Weiss, M.; Sotirelis, T. S.; Raouafi, N.-E.; Kessel, R. L.; Becker, H. N.

    2014-10-01

    The overarching goal and purpose of the study of space weather is clear—to understand and address the issues caused by solar disturbances on humans and technological systems. Space weather has evolved in the past few decades from a collection of concerned agencies and researchers to a critical function of the National Weather Service of NOAA. The general effects have also evolved from the well-known telegraph disruptions of the mid-1800s to modern day disturbances of the electric power grid, communications and navigation, human spaceflight and spacecraft systems. The last two items in this list, and specifically the effects of penetrating radiation, were the impetus for the space weather broadcast implemented on NASA's Van Allen Probes' twin pair of satellites, launched in August of 2012 and orbiting directly through Earth's severe radiation belts. The Van Allen Probes mission, formerly the Radiation Belt Storm Probes (RBSP), was renamed soon after launch to honor the discoverer of Earth's radiation belts at the beginning of the space age, the late James Van Allen (the spacecraft themselves are still referred to as RBSP-A and RBSP-B). The Van Allen Probes are one part of NASA's Living With a Star program formulated to advance the scientific understanding of the connection between solar disturbances, the resulting heliospheric conditions, and their effects on the geospace and Earth environment.

  2. Current interpretations of periodontal probing evaluations: diagnostic and therapeutic implications.

    PubMed

    Greenstein, Gary

    2005-06-01

    Probing depth assessments are the backbone of a periodontal evaluation. However, they should be interpreted with respect to current information regarding their diagnostic and therapeutic implications. Controlled clinical trials and review papers that related probing depth determinations to diagnosing periodontal disease or assessments of therapy were selected for evaluation. The literature indicates that increased probing depths usually are related to loss of clinical attachment; however, they may not reflect periodontal disease or disease progression. When characteristics pertaining to deep and shallow sites are compared, deep sites have more bleeding on probing, elevated bacterial levels, reduced ability of oral hygiene to alter subgingival microflora, less effective root instrumentation, and a greater percentage of pockets that experience disease progression in treated and untreated sites. However, individual deep sites are not good predictors of disease progression. The preponderance of information indicates that it is preferable, but not always essential, to have shallow sites around teeth to attain and maintain periodontal health. Ultimately, therapeutic decisions based on probing depths are influenced by the medical and dental history of the patient, a practical interpretation of the literature, and clinical experience.

  3. Radiation: Behavioral Implications in Space

    DTIC Science & Technology

    1988-01-01

    anti-histamine were done with monkeys and rats [26,27]. Chlorpheniramine attenuated PD up to 30 min post-irradiation, but after that time, monkey...PD for 30 min seems to be a com- mon denominator already noted with chlorpheniramine . However, to be an acceptable agent for use in space, the final BR

  4. Probing dense granular materials by space-time dependent perturbations.

    PubMed

    Kondic, L; Dybenko, O M; Behringer, R P

    2009-04-01

    The manner in which signals propagate through dense granular systems in both space and time is not well understood. In order to probe this process, we carry out discrete element simulations of the system response to excitations where we control the driving frequency and wavelength independently. Fourier analysis shows that properties of the signal depend strongly on the space-time scales of the perturbation. The features of the response provide a test bed for models that predict statistical and continuum space-time properties. We illustrate this connection between microscale physics and macroscale behavior by comparing the system response to a simple elastic model with damping.

  5. Van Allen Probes Science Gateway and Space Weather Data Processing

    NASA Astrophysics Data System (ADS)

    Romeo, G.; Barnes, R. J.; Weiss, M.; Fox, N. J.; Mauk, B.; Potter, M.; Kessel, R.

    2014-12-01

    The Van Allen Probes Science Gateway acts as a centralized interface to the instrument Science Operation Centers (SOCs), provides mission planning tools, and hosts a number of science related activities such as the mission bibliography. Most importantly, the Gateway acts as the primary site for processing and delivering the VAP Space Weather data to users. Over the past year, the web-site has been completely redesigned with the focus on easier navigation and improvements of the existing tools such as the orbit plotter, position calculator and magnetic footprint tool. In addition, a new data plotting facility has been added. Based on HTML5, which allows users to interactively plot Van Allen Probes summary and space weather data. The user can tailor the tool to display exactly the plot they wish to see and then share this with other users via either a URL or by QR code. Various types of plots can be created, including simple time series, data plotted as a function of orbital location, and time versus L-Shell. We discuss the new Van Allen Probes Science Gateway and the Space Weather Data Pipeline.

  6. Future exploration of the asteroids. [by space probes

    NASA Technical Reports Server (NTRS)

    Morrison, D.; Niehoff, J.

    1979-01-01

    Future possibilities for the further study of the asteroids are reviewed, with particular attention paid to space missions for their direct exploration. The role of traditional ground-based and earth orbiting techniques is examined briefly, and it is concluded that although astronomical techniques are presently at their peak, and despite the opportunities provided by the Infrared Astronomical satellite, the Space Telescope and Spacelab Infrared Telescope Facility, the next major step will require direct exploration by space probes to obtain information on asteroid surface chemistry, geology and bulk properties. Various mission modes and propulsion systems for a first multi-target asteroid mission are discussed, including flyby, rendezvous, landing and sample return, and ion-drive propulsion systems. Science payloads for a basic rendezvous mission are considered, and target selection for multi-asteroid flyby tours and rendezvous tours is discussed. Consideration is also given to sample return missions for the evaluation of the asteroid as potential resources.

  7. Deep Space Network Capabilities for Receiving Weak Probe Signals

    NASA Technical Reports Server (NTRS)

    Asmar, Sami; Johnston, Doug; Preston, Robert

    2005-01-01

    Planetary probes can encounter mission scenarios where communication is not favorable during critical maneuvers or emergencies. Launch, initial acquisition, landing, trajectory corrections, safing. Communication challenges due to sub-optimum antenna pointing or transmitted power, amplitude/frequency dynamics, etc. Prevent lock-up on signal and extraction of telemetry. Examples: loss of Mars Observer, nutation of Ulysses, Galileo antenna, Mars Pathfinder and Mars Exploration Rovers Entry, Descent, and Landing, and the Cassini Saturn Orbit Insertion. A Deep Space Network capability to handle such cases has been used successfully to receive signals to characterize the scenario. This paper will describe the capability and highlight the cases of the critical communications for the Mars rovers and Saturn Orbit Insertion and preparation radio tracking of the Huygens probe at (non-DSN) radio telescopes.

  8. Welded Titanium Case for Space-Probe Rocket Motor

    NASA Technical Reports Server (NTRS)

    Brothers, A. J.; Boundy, R. A.; Martens, H. E.; Jaffe, L. D.

    1959-01-01

    The high strength-to-weight ratio of titanium alloys suggests their use for solid-propellant rocket-motor cases for high-performance orbiting or space-probe vehicles. The paper describes the fabrication of a 6-in.-diam., 0.025-in.-wall rocket-motor from the 6A1-4V titanium alloy. The rocket-motor case, used in the fourth stage of a successful JPL-NASA lunar-probe flight, was constructed using a design previously proven satisfactory for Type 410 stainless steel. The nature and scope of the problems peculiar to the use of the titanium alloy, which effected an average weight saving of 34%, are described.

  9. The medical implications of space tourism.

    PubMed

    Tarzwell, R

    2000-06-01

    Commercial space travel may soon be a reality. If so, microgravity, high acceleration, and radiation exposure, all known hazards, will be accessible to the general public. Therefore, space tourism has medical implications. Even though the first flights will feature space exposure times of only a few minutes, the potential may someday exist for exposure times long enough to warrant careful consideration of the potential hazards to the space-faring public. The effects of acceleration and microgravity exposure are well known on the corps of astronauts and cosmonauts. The effects of space radiation are partially known on astronauts, but much remains to be discovered. However, there are problems using astronaut data to make inferences about the general public. Astronauts are not necessarily representative of the general public, since they are highly fit, highly screened individuals. Astronaut data can tell us very little about the potential hazards of microgravity in pediatric, obstetric and geriatric populations, all of whom are potential space tourists. Key issues in standard setting will be determining acceptable limits of pre-existing disease and inferring medical standards from mission profiles. It will not be a trivial task drafting minimal medical standards for commercial space travel. It will require the collaboration of space medicine physicians, making the best guesses possible, based on limited amounts of data, with limited applicability. A helpful departure point may be the USAF Class 3 medical standard, applicable to NASA payload specialists. It is time to begin preliminary discussions toward defining those standards. acceleration, aerospace medicine, medical standards, microgravity, radiation, space, space tourism, environmental hazards, environmental medicine.

  10. Orbital synthesis for deep space probes at the Institute of Space and Astronautical Science

    NASA Astrophysics Data System (ADS)

    Kawaguchi, Junichiro

    The orbital design for the deep space probes is presented with the analysis of parking orbit and earth trajectory. The patched conic method and gravity assist are discussed in the framework of the powered swingby theory. The trajectories for the Sakegake extended mission are examined, and computer software for orbital design and the orbital control system is discussed.

  11. IEC Thrusters for Space Probe Applications and Propulsion

    SciTech Connect

    Miley, George H.; Momota, Hiromu; Wu Linchun; Reilly, Michael P.; Teofilo, Vince L.; Burton, Rodney; Dell, Richard; Dell, Dick; Hargus, William A.

    2009-03-16

    Earlier conceptual design studies (Bussard, 1990; Miley et al., 1998; Burton et al., 2003) have described Inertial Electrostatic Confinement (IEC) fusion propulsion to provide a high-power density fusion propulsion system capable of aggressive deep space missions. However, this requires large multi-GW thrusters and a long term development program. As a first step towards this goal, a progression of near-term IEC thrusters, stating with a 1-10 kWe electrically-driven IEC jet thruster for satellites are considered here. The initial electrically-powered unit uses a novel multi-jet plasma thruster based on spherical IEC technology with electrical input power from a solar panel. In this spherical configuration, Xe ions are generated and accelerated towards the center of double concentric spherical grids. An electrostatic potential well structure is created in the central region, providing ion trapping. Several enlarged grid opening extract intense quasi-neutral plasma jets. A variable specific impulse in the range of 1000-4000 seconds is achieved by adjusting the grid potential. This design provides high maneuverability for satellite and small space probe operations. The multiple jets, combined with gimbaled auxiliary equipment, provide precision changes in thrust direction. The IEC electrical efficiency can match or exceed efficiencies of conventional Hall Current Thrusters (HCTs) while offering advantages such as reduced grid erosion (long life time), reduced propellant leakage losses (reduced fuel storage), and a very high power-to-weight ratio. The unit is ideally suited for probing missions. The primary propulsive jet enables delicate maneuvering close to an object. Then simply opening a second jet offset 180 degrees from the propulsion one provides a 'plasma analytic probe' for interrogation of the object.

  12. Langmuir probe measurements aboard the International Space Station

    NASA Astrophysics Data System (ADS)

    Kirov, B.; Asenovski, S.; Bachvarov, D.; Boneva, A.; Grushin, V.; Georgieva, K.; Klimov, S. I.

    2016-12-01

    In the current work we describe the Langmuir Probe (LP) and its operation on board the International Space Station. This instrument is a part of the scientific complex "Ostonovka". The main goal of the complex is to establish, on one hand how such big body as the International Space Station affects the ambient plasma and on the other how Space Weather factors influence the Station. The LP was designed and developed at BAS-SRTI. With this instrument we measure the thermal plasma parameters-electron temperature Te, electron and ion concentration, respectively Ne and Ni, and also the potential at the Station's surface. The instrument is positioned at around 1.5 meters from the surface of the Station, at the Russian module "Zvezda", located at the farthermost point of the Space Station, considering the velocity vector. The Multi- Purpose Laboratory (MLM) module is providing additional shielding for our instrument, from the oncoming plasma flow (with respect to the velocity vector). Measurements show that in this area, the plasma concentration is two orders of magnitude lower, in comparison with the unperturbed areas. The surface potential fluctuates between-3 and-25 volts with respect to the ambient plasma. Fast upsurges in the surface potential are detected when passing over the twilight zone and the Equatorial anomaly.

  13. Electric Field Double Probe Measurements for Ionospheric Space Plasma Experiments

    NASA Technical Reports Server (NTRS)

    Pfaff, R.

    1999-01-01

    Double probes represent a well-proven technique for gathering high quality DC and AC electric field measurements in a variety of space plasma regimes including the magnetosphere, ionosphere, and mesosphere. Such experiments have been successfully flown on a variety of spacecraft including sounding rockets and satellites. Typical instrument designs involve a series of trades, depending on the science objectives, type of platform (e.g., spinning or 3-axis stabilized), expected plasma regime where the measurements will be made, available telemetry, budget, etc. In general, ionospheric DC electric field instruments that achieve accuracies of 0.1 mV/m or better, place spherical sensors at large distances (10m or more) from the spacecraft body in order to extend well beyond the spacecraft wake and sheath and to achieve large signal-to-noise ratios for DC and long wavelength measurements. Additional sets of sensors inboard of the primary, outermost sensors provide useful additional information, both for diagnostics of the plasma contact potentials, which particularly enhance the DC electric field measurements on non-spinning spacecraft, and for wavelength and phase velocity measurements that use the spaced receiver or "interferometer" technique. Accurate attitude knowledge enables B times V contributions to be subtracted from the measured potentials, and permits the measured components to be rotated into meaningful geophysical reference frames. We review the measurement technique for both DC and wave electric field measurements in the ionosphere discussing recent advances involving high resolution burst memories, multiple baseline double probes, new sensor surface materials, biasing techniques, and other considerations.

  14. Probing critical surfaces in momentum space using real-space entanglement entropy: Bose versus Fermi

    NASA Astrophysics Data System (ADS)

    Lai, Hsin-Hua; Yang, Kun

    2016-03-01

    A codimension-one critical surface in momentum space can be either a familiar Fermi surface, which separates occupied states from empty ones in the noninteracting fermion case, or a novel Bose surface, where gapless bosonic excitations are anchored. The presence of such surfaces gives rise to logarithmic violation of entanglement entropy area law. When they are convex, we show that the shape of these critical surfaces can be determined by inspecting the leading logarithmic term of real-space entanglement entropy. The fundamental difference between a Fermi surface and a Bose surface is revealed by the fact that the logarithmic terms in entanglement entropies differ by a factor of 2: SlogBose=2 SlogFermi , even when they have identical geometry. Our method has remarkable similarity with determining Fermi surface shape using quantum oscillation. We also discuss possible probes of concave critical surfaces in momentum space.

  15. Floating Potential Probe Deployed on the International Space Station

    NASA Technical Reports Server (NTRS)

    Ferguson, Dale C.

    2001-01-01

    In the spring and summer of 2000, at the request of the International Space Station (ISS) Program Office, a Plasma Contactor Unit Tiger Team was set up to investigate the threat of the ISS arcing in the event of a plasma contactor outage. Modeling and ground tests done under that effort showed that it is possible for the external structure of the ISS to become electrically charged to as much as -160 V under some conditions. Much of this work was done in anticipation of the deployment of the first large ISS solar array in November 2000. It was recognized that, with this deployment, the power system would be energized to its full voltage and that the predicted charging would pose an immediate threat to crewmembers involved in extravehicular activities (EVA's), as well as long-term damage to the station structure, were the ISS plasma contactors to be turned off or stop functioning. The Floating Potential Probe was conceived, designed, built, and deployed in record time by a crack team of scientists and engineers led by the NASA Glenn Research Center in response to ISS concerns about crew safety.

  16. Preliminary Results from the Space Probe Pioneer V

    NASA Technical Reports Server (NTRS)

    Fan, C. Y.; Meyer, P.; Simpson, J. A.

    1960-01-01

    The space probe Pioneer V was launched March 11, 1960, into an orbit around the sun and inside the orbit of earth. The scientific apparatus included instruments identical with the University of Chicago apparatus used on Explorer VI [Fan, Meyer, and Simpson, 1960b], namely, energetic particle detectors which measure fluxes of protons with energies greater than 75 Mev, electrons with energies greater than 15 Mev, and the bremsstrahlung from electrons and y rays of lower energy. Simultaneously with the measurements in Pioneer V a series of four neutron monitor piles were recording the changes in cosmic radiation intensity at the earth. We report here on some preliminary results obtained from the Chicago experiments during the time within which Pioneer V traveled to a distance of approximately 8 x 10 km from earth. Beginning on March 20, solar activity rapidly increased with many solar flares, radio noise bursts, etc., over a period of 10 days. Most of our results relate to this period. The preliminary data are given in Figures 1 and 2.

  17. Space industrialization. Volume 3: World and domestic implications

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The status of worldwide space industralization activities is assessed as well as the benefits to be anticipated from enhanced activities. Methods for stimulating space industralization growth are discussed with emphasis on foreign and international activities, national and world impact assessments, industry/government interfaces, legal implications, institutional implications, economics and capitalization, and implementation issues and recommendations.

  18. Magnetically Insulated Baffled Probe Measurement of Unfiltered Fluctuating Space Potential in the Texas Helimak

    NASA Astrophysics Data System (ADS)

    Koepke, M. E.; Nogami, S. H.; Demidov, V. I.; Williams, C. B.; Gentle, K.

    2016-10-01

    Success is reported in employing magnetically insulated baffled (MIB) probes for the measurement of fluctuating space potential in the Texas Helimak. The combination of the MIB probe and an unbaffled probe provides the necessary ingredients for determining cross-field transport without contamination between fluctuating space potential and electron temperature. The performance of the MIB probe is quantified by its ability to produce a probe characteristic with partially reduced magnitude of electron saturation current. The baffled probe employed in the 2016 experiments performed optimally (i.e., the magnitude of the electron saturation current is equal to the magnitude of the ion saturation current), meaning there is no difference between the probe floating potential and the space potential. The performance of the baffled probe is compared to the performance of the plug probe, tested in 2015 on the Texas Helimak. Recent radial scans at the plasma edge of unfiltered fluctuating space potential are presented. Travel support from a Big XII Faculty Fellowship is gratefully acknowledged. Collaboration in probe construction with and experimental assistance by K. Carter are gratefully acknowledged.

  19. Outer planet probe navigation. [considering Pioneer space missions

    NASA Technical Reports Server (NTRS)

    Friedman, L.

    1974-01-01

    A series of navigation studies in conjunction with outer planet Pioneer missions are reformed to determine navigation requirements and measurement systems in order to target probes. Some particular cases are established where optical navigation is important and some cases where radio alone navigation is suffucient. Considered are a direct Saturn mission, a Saturn Uranus mission, a Jupiter Uranus mission, and a Titan probe mission.

  20. Space Systems Failures: Disasters and Rescues of Satellites, Rocket and Space Probes

    NASA Astrophysics Data System (ADS)

    Harland, David M.; Lorenz, Ralph

    In the 1960s and 1970s deep space missions were dispatched in pairs in case one was lost in launch or failed during its journey. Following the triumphs of the Viking landings on Mars in 1976 and both Voyagers spacecraft successfully surveying the outer giant planets of the Solar System, it was decided by NASA to cut costs and send out just a single probe. Although Magellan successfully mapped Venus by radar, it suffered from problems during the flight. Then came the loss of Mars Observer, whose engine exploded as it was preparing to enter Mars' orbit because it was using technology designed for Earth's satellites and the engine was not suited to spending several months in space.

  1. Langmuir Probes for Obstanovka Experiment Aboard the Russian Segment of the International Space Station

    DTIC Science & Technology

    2010-08-04

    segment of the International Space Station 5a. CONTRACT NUMBER FA8655-08-1-3006 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...1 REPORT ON FA8655-08-1-3006 LANGMUIR PROBES FOR “OBSTANOVKA” EXPERIMENT ABOARD THE RUSSIAN SEGMENT OF THE INTERNATIONAL SPACE STATION August...Russian segment of the International Space Station ”. INTRODUCTION Two Langmuir electrostatic probes are included in the experiment "Obstanovka

  2. Deep Space Network capabilities for receiving weak probe signals

    NASA Technical Reports Server (NTRS)

    Asmar, Sami; Johnston, Doug; Preston, Robert

    2004-01-01

    This paper will describe the capability and highlight the cases of the critical communications for the Mars rovers and Saturn Orbit Insertion and preparation radio tracking of the Huygens probe at (non-DSN) radio telescopes.

  3. Deep Space Network capabilities for receiving weak probe signals

    NASA Technical Reports Server (NTRS)

    Asmar, Sami; Johnston, Doug; Preston, Robert

    2004-01-01

    This paper will describe the capability and highlight the cases of the critical communications for the Mars rovers and Saturn Orbit Insertion and preparation radio tracking of the Huygens probe at (non-DSN) radio telescopes.

  4. Positioning Reduction of Deep Space Probes Based on VLBI Tracking

    NASA Astrophysics Data System (ADS)

    Qiao, S. B.

    2011-11-01

    ) Investigate the application of Kalman filter to the positioning reduction of deep space probes and develop related software systems. In summary, the progress in this dissertation is made in the positioning reduction of deep space probes tracked by VLBI concerning the algorithm study, software development, real observation processing and so on, while a further study is still urgent and arduous.

  5. Probing Critical Surfaces in Momentum Space Using Real-Space Entanglement Entropy: Bose versus Fermi

    NASA Astrophysics Data System (ADS)

    Yang, Kun; Lai, Hsin-Hua

    A co-dimension one critical surface in the momentum space can be either a familiar Fermi surface, which separates occupied states from empty ones in the non-interacting fermion case, or a novel Bose surface, where gapless bosonic excitations are anchored. Their presence gives rise to logarithmic violation of entanglement entropy area law. When they are convex, we show that the shape of these critical surfaces can be determined by inspecting the leading logarithmic term of real space entanglement entropy. The fundamental difference between a Fermi surface and a Bose surface is revealed by the fact that the logarithmic terms in entanglement entropies differ by a factor of two: SlogBose = 2SlogFermi , even when they have identical geometry. Our method has remarkable similarity with determining Fermi surface shape using quantum oscillation. We also discuss possible probes of concave critical surfaces in momentum space. HHL and KY acknowledge the National Science Foundation through Grants No. DMR-1004545, DMR-1157490, No. DMR-1442366, and State of Florida. HHL is also partially supported by NSF Grant No. DMR-1309531, and the Smalley Postdoctoral Fellowship in Quantum Ma.

  6. U.S. commercial space policies - Implications for developing countries

    NASA Technical Reports Server (NTRS)

    Gillam, Isaac T., IV; Stone, Barbara A.

    1987-01-01

    Recent U.S. policy developments on the commercial use of space are summarized and their international implications are considered. Attention is given to successful applications of technology developed in space, including an implantable cancer medication system, an implantable defibrillator, an ultrasonic residual stress monitor, and aquaculture treatment techniques. NASA projects involving bioengineering and rehabilitation applications are summarized, and plans to investigate high-temperature superconductors in space are addressed. Recent agreements entred into by NASA for space commercial studies are reviewed.

  7. U.S. commercial space policies - Implications for developing countries

    NASA Technical Reports Server (NTRS)

    Gillam, Isaac T., IV; Stone, Barbara A.

    1987-01-01

    Recent U.S. policy developments on the commercial use of space are summarized and their international implications are considered. Attention is given to successful applications of technology developed in space, including an implantable cancer medication system, an implantable defibrillator, an ultrasonic residual stress monitor, and aquaculture treatment techniques. NASA projects involving bioengineering and rehabilitation applications are summarized, and plans to investigate high-temperature superconductors in space are addressed. Recent agreements entred into by NASA for space commercial studies are reviewed.

  8. Early Results from the Floating Potential Probe on the International Space Station

    NASA Technical Reports Server (NTRS)

    Morton, Thomas L.; Ferguson, Dale C.

    2001-01-01

    This viewgraph presentation provides information on the Floating Potential Probe (FPP) on the International Space Station (ISS). The FPP measures the body voltage (electric potential) of the, and the measurements are then transmitted to Earth.

  9. Data link relay design. [space probe with entry at Uranus

    NASA Technical Reports Server (NTRS)

    Parsons, P.

    1974-01-01

    The data link for the Ames baseline probe as applied to the MJU spacecraft specifically with an entry at Uranus is analyzed. A frequency analysis, a trajectory analysis, and a discussion of the effects on the spacecraft design by the data link are presented. The possibilities of a two-way link are considered.

  10. Military space station implications. Study project

    SciTech Connect

    Bourne, G.D.; Skirvin, G.D.; Wilson, G.R.

    1987-03-23

    Justifying the relevancy of a Manned Military Space Station (MMSS) and subsequently proposing its deployment to capitalize upon the United States' national security interests is the essence and purpose of this group study project. The MMSS is intended to perform a two-fold purpose: (1) facilitate military peacetime operations while simultaneously supporting and promoting civilian space initiatives; and, (2) act as a force multiplier for space and terrestrial force operations in the event of conventional, theater nuclear, and/or strategic nuclear war. Data to support the future value of the MMSS was obtained from individual and group research using unclassified sources such as professional journals, books, US Air Force Staff College reference material, and information from the US Air Force space coordinating staff in Washington, DC. The importance of space to our future and especially of a MMSS by America's national leaders and its people has yet to be fully appreciated and/or realized. The significance of space and its nexus to the United States' national security has been growing dramatically in importance since the launching of the Sputnik in 1957 by Russian. Space, as the forth dimension, cannot and should not be understated in importance as it relates to commercialism, deterrence to war, and to the stability of world order.

  11. MARINER 9 SPACE PROBE UNDERGOES FINAL CHECKS PRIOR TO ENCAPSULATION

    NASA Technical Reports Server (NTRS)

    1971-01-01

    A technician checks the Mariner I spacecraft prior to its encapsulation for launch to Mars. An Atlas-Centaur rocket successfully launched the mars-bound spacecraft from Cape Kennedy at 6:23 p.m. EDT, May 30, 1971. Designated Mariner 9 following launch, the probe will arrive at Mars in mid-November. It will transmit scientific data about that planet's surface and atmosphere.

  12. Toxicological implications of extended space flights.

    PubMed

    Weiss, B; Utell, M; Morrow, P

    1992-01-01

    The dominant reason for exposing humans to the risks of space flight is their ability to perform complex tasks and make complex decisions. To fulfill such a role, crews must be shielded against even incipient degradation of performance capacity. The space environment contains potential hazards ranging from microgravity to infectious microorganisms to chemical toxicants. An extensive literature indicates that incipient disruptions of function may occur at low levels of exposure to toxic agents and degrade performance. Such questions need to be pursued before irreversible decisions are made about space vehicle design.

  13. Space Weather Operation at KASI with Van Allen Probes Beacon Signals

    NASA Astrophysics Data System (ADS)

    Lee, J.; Kim, K. C.; Romeo, G.; Ukhorskiy, S.; Sibeck, D. G.; Kessel, R.; Mauk, B.; Giles, B. L.; Gu, B. J.; Lee, H.

    2016-12-01

    The Van Allen Probes are the first NASA mission broadcasting real time data in the Earth's radiation belts for space weather operation. Korea Astronomy and Space Science Institute has contributed in data receiving from Van Allen Probes with 7 m satellite tracking antenna since 2012 and used the data for space weather operation. It takes approximately 15 minutes from measurements to produce Level 1 data. In this study, we show how the Van Allen Probes data is handled for monitoring space weather conditions at geostationary orbit (GEO) by highlighting the Saint Patrick's Day storm occurred in 2015. During storm time, Probe-A data shows a significant increase of relativistic electron flux at L=3. The electrons diffuse out and results in large increase of > 2MeV electron flux on GEO. By monitoring the radial distribution of energetic electrons, we could predict relativistic electron enhancement events that potentially threat satellite operation. We conclude that the combination of Van Allen Probes and NOAA-GOES data can provide improved space environment information to geostationary satellite operators. In addition, the lessons learned from Van Allen Probes are that more data receiving sites are necessary and data connections should be monitored for operational data service.

  14. Photosynthesis and Its Implications for Space Research

    NASA Astrophysics Data System (ADS)

    de Vera, J. P. P.; Leya, T.; Lorek, A.; Koncz, A.; de La Torre Noetzel, R.; Kozyrovska, N.; Burlak, O.; Foing, B.

    2010-04-01

    Photosynthesis is useful for biosignature definition, for the definition of the habitability of a planet, for research on the likelihood of Panspermia and for use in manned space flight missions by integration into life supporting systems.

  15. Wilkinson Microwave Anisotropy Probe data and the curvature of space

    NASA Astrophysics Data System (ADS)

    Uzan, Jean-Philippe; Kirchner, Ulrich; Ellis, George F. R.

    2003-10-01

    Inter alia, the high-precision Wilkinson Microwave Anisotropy Probe (WMAP) data on cosmic background radiation marginally indicate that the Universe has positively curved (and hence spherical) spatial sections. In this Letter, we take this data seriously and consider some of the consequences for the background dynamics. In particular, we show that this implies a limit to the number of e-foldings that could have taken place in the inflationary epoch; however, this limit is consistent with some inflationary models that solve all the usual cosmological problems and that are consistent with standard structure formation theory.

  16. Reagent based DOS: a "Click, Click, Cyclize" strategy to probe chemical space.

    PubMed

    Rolfe, Alan; Lushington, Gerald H; Hanson, Paul R

    2010-05-07

    The synthesis of small organic molecules as probes for discovering new therapeutic agents has been an important aspect of chemical-biology. Herein we report a reagent-based, diversity-oriented synthetic (DOS) strategy to probe chemical and biological space via a "Click, Click, Cyclize" protocol. In this DOS approach, three sulfonamide linchpins underwent cyclization protocols with a variety of reagents to yield a collection of structurally diverse S-heterocycles. In silico analysis is utilized to evaluate the diversity of the compound collection against chemical space (PC analysis), shape space (PMI) and polar surface area (PSA) calculations.

  17. Space Biosensor Systems: Implications for Technology Transfer

    NASA Technical Reports Server (NTRS)

    Hines, J. W.; Somps, C. J.; Madou, M.; Imprescia, Clifford C. (Technical Monitor)

    1997-01-01

    To meet the need for continuous, automated monitoring of animal subjects, including; humans, during space flight, NASA is developing advanced physiologic sensor and biotelemetry system technologies. The ability to continuously track basic physiological parameters, such as heart rate, blood pH, and body temperature, in untethered subjects in space is a challenging task. At NASA's Ames Research Center, where a key focus is gravitational biology research, engineers have teamed with life scientists to develop wireless sensor systems for automated physiologic monitoring of animal models as small as the rat. This technology is also being adapted, in collaboration with medical professionals, to meet human clinical monitoring needs both in space and on the ground. Thus, these advanced monitoring technologies have important dual-use functions; they meet space flight data collection requirements and constraints, while concurrently addressing a number of monitoring and data acquisition challenges on the ground in areas of clinical monitoring and biomedical research. Additional applications for these and related technologies are being sought and additional partnerships established that enhance development efforts, reduce costs and facilitate technology infusion between the public and private sectors. This paper describes technology transfer and co-development projects that have evolved out of NASA's miniaturized, implantable chemical sensor development efforts.

  18. Probing chemical space with alkaloid-inspired libraries

    NASA Astrophysics Data System (ADS)

    McLeod, Michael C.; Singh, Gurpreet; Plampin, James N.; Rane, Digamber; Wang, Jenna L.; Day, Victor W.; Aubé, Jeffrey

    2014-02-01

    Screening of small-molecule libraries is an important aspect of probe and drug discovery science. Numerous authors have suggested that bioactive natural products are attractive starting points for such libraries because of their structural complexity and sp3-rich character. Here, we describe the construction of a screening library based on representative members of four families of biologically active alkaloids (Stemonaceae, the structurally related cyclindricine and lepadiformine families, lupin and Amaryllidaceae). In each case, scaffolds were based on structures of the naturally occurring compounds or a close derivative. Scaffold preparation was pursued following the development of appropriate enabling chemical methods. Diversification provided 686 new compounds suitable for screening. The libraries thus prepared had structural characteristics, including sp3 content, comparable to a basis set of representative natural products and were highly rule-of-five compliant.

  19. Probing chemical space with alkaloid-inspired libraries.

    PubMed

    McLeod, Michael C; Singh, Gurpreet; Plampin, James N; Rane, Digamber; Wang, Jenna L; Day, Victor W; Aubé, Jeffrey

    2014-02-01

    Screening of small-molecule libraries is an important aspect of probe and drug discovery science. Numerous authors have suggested that bioactive natural products are attractive starting points for such libraries because of their structural complexity and sp(3)-rich character. Here, we describe the construction of a screening library based on representative members of four families of biologically active alkaloids (Stemonaceae, the structurally related cyclindricine and lepadiformine families, lupin and Amaryllidaceae). In each case, scaffolds were based on structures of the naturally occurring compounds or a close derivative. Scaffold preparation was pursued following the development of appropriate enabling chemical methods. Diversification provided 686 new compounds suitable for screening. The libraries thus prepared had structural characteristics, including sp(3) content, comparable to a basis set of representative natural products and were highly rule-of-five compliant.

  20. Toxicological implications of extended space flights

    NASA Technical Reports Server (NTRS)

    Weiss, Bernard; Utell, Mark; Morrow, Paul

    1992-01-01

    This paper draws attention to the needs and mechanisms for shielding crewmembers on long-duration space flights from hazards related to chemical toxicants. Specific attention is given to existing data on sources of impaired performance, namely, neurotoxicants, respiratory infections, pulmonary function. The behavioral effects associated with long-term exposure to volatile organic solvents can impair crucial functional parameters of space flight and mission objectives. Respiratory infections contribute to performance decrements of up to 20 percent, and pulmonary function can be impaired by contaminants such as ozone leading to reduced performance. It is concluded that these and other sources of toxicologically induced performance reductions be studied since they impinge on vehicle design and mission objectives.

  1. Toxicological implications of extended space flights

    NASA Technical Reports Server (NTRS)

    Weiss, Bernard; Utell, Mark; Morrow, Paul

    1992-01-01

    This paper draws attention to the needs and mechanisms for shielding crewmembers on long-duration space flights from hazards related to chemical toxicants. Specific attention is given to existing data on sources of impaired performance, namely, neurotoxicants, respiratory infections, pulmonary function. The behavioral effects associated with long-term exposure to volatile organic solvents can impair crucial functional parameters of space flight and mission objectives. Respiratory infections contribute to performance decrements of up to 20 percent, and pulmonary function can be impaired by contaminants such as ozone leading to reduced performance. It is concluded that these and other sources of toxicologically induced performance reductions be studied since they impinge on vehicle design and mission objectives.

  2. National Security Implications of Inexpensive Space Access,

    DTIC Science & Technology

    2007-11-02

    to these techniques (such as eclipsing adversary solar panels or jamming uplinks), however, because rendezvous with, and capture of, hostile...are difficult to foresee and were already proposed as missions for the Space Shuttle in the early 1980s (and then turned out poorly). It may, in fact...these discussions in the late 1980s and early 1990s. At this point, political forces converged with SSTO technology. At the beginning of the Bush

  3. Space WARC 1985 - Legal Issues and Implications.

    DTIC Science & Technology

    1984-01-01

    both an international governmental organization, and an international corporation 165. INTELSAT Operating Agreement, T.I.A.S. 7532 (1971). The Operating...by their PTT. In the U.S. , government monopoly over telecommunications does not exist; the Communications Satellite Corporation (COMSAT) signed the...Arab Corporation for Space Communications (ARABSAT), was - formed by the countries of the Arab League in 1976, with the objective of establishing

  4. Probing Planckian physics in de Sitter space with quantum correlations

    SciTech Connect

    Feng, Jun; Zhang, Yao-Zhong; Gould, Mark D.; Fan, Heng; Sun, Cheng-Yi; Yang, Wen-Li

    2014-12-15

    We study the quantum correlation and quantum communication channel of both free scalar and fermionic fields in de Sitter space, while the Planckian modification presented by the choice of a particular α-vacuum has been considered. We show the occurrence of degradation of quantum entanglement between field modes for an inertial observer in curved space, due to the radiation associated with its cosmological horizon. Comparing with standard Bunch–Davies choice, the possible Planckian physics causes some extra decrement on the quantum correlation, which may provide the means to detect quantum gravitational effects via quantum information methodology in future. Beyond single-mode approximation, we construct proper Unruh modes admitting general α-vacua, and find a convergent feature of both bosonic and fermionic entanglements. In particular, we show that the convergent points of fermionic entanglement negativity are dependent on the choice of α. Moreover, an one-to-one correspondence between convergent points H{sub c} of negativity and zeros of quantum capacity of quantum channels in de Sitter space has been proved. - Highlights: • Quantum correlation and quantum channel in de Sitter space are studied. • Gibbons–Hawking effect causes entanglement degradation for static observer. • Planckian physics causes extra decrement on quantum correlation. • Convergent feature of negativity relies on the choice of alpha-vacua. • Link between negativity convergence and quantum channel capacity is given.

  5. Detecting 3D Vegetation Structure with the Galileo Space Probe: Can a Distant Probe Detect Vegetation Structure on Earth?

    PubMed Central

    2016-01-01

    Sagan et al. (1993) used the Galileo space probe data and first principles to find evidence of life on Earth. Here we ask whether Sagan et al. (1993) could also have detected whether life on Earth had three-dimensional structure, based on the Galileo space probe data. We reanalyse the data from this probe to see if structured vegetation could have been detected in regions with abundant photosynthetic pigments through the anisotropy of reflected shortwave radiation. We compare changing brightness of the Amazon forest (a region where Sagan et al. (1993) noted a red edge in the reflectance spectrum, indicative of photosynthesis) as the planet rotates to a common model of reflectance anisotropy and found measured increase of surface reflectance of 0.019 ± 0.003 versus a 0.007 predicted from only anisotropic effects. We hypothesize the difference was due to minor cloud contamination. However, the Galileo dataset had only a small change in phase angle (sun-satellite position) which reduced the observed anisotropy signal and we demonstrate that theoretically if the probe had a variable phase angle between 0–20°, there would have been a much larger predicted change in surface reflectance of 0.1 and under such a scenario three-dimensional vegetation structure on Earth could possibly have been detected. These results suggest that anisotropic effects may be useful to help determine whether exoplanets have three-dimensional vegetation structure in the future, but that further comparisons between empirical and theoretical results are first necessary. PMID:27973530

  6. Detecting 3D Vegetation Structure with the Galileo Space Probe: Can a Distant Probe Detect Vegetation Structure on Earth?

    PubMed

    Doughty, Christopher E; Wolf, Adam

    2016-01-01

    Sagan et al. (1993) used the Galileo space probe data and first principles to find evidence of life on Earth. Here we ask whether Sagan et al. (1993) could also have detected whether life on Earth had three-dimensional structure, based on the Galileo space probe data. We reanalyse the data from this probe to see if structured vegetation could have been detected in regions with abundant photosynthetic pigments through the anisotropy of reflected shortwave radiation. We compare changing brightness of the Amazon forest (a region where Sagan et al. (1993) noted a red edge in the reflectance spectrum, indicative of photosynthesis) as the planet rotates to a common model of reflectance anisotropy and found measured increase of surface reflectance of 0.019 ± 0.003 versus a 0.007 predicted from only anisotropic effects. We hypothesize the difference was due to minor cloud contamination. However, the Galileo dataset had only a small change in phase angle (sun-satellite position) which reduced the observed anisotropy signal and we demonstrate that theoretically if the probe had a variable phase angle between 0-20°, there would have been a much larger predicted change in surface reflectance of 0.1 and under such a scenario three-dimensional vegetation structure on Earth could possibly have been detected. These results suggest that anisotropic effects may be useful to help determine whether exoplanets have three-dimensional vegetation structure in the future, but that further comparisons between empirical and theoretical results are first necessary.

  7. Environmental interaction implications for large space systems

    NASA Technical Reports Server (NTRS)

    Miller, E.; Fischbein, W.; Stauber, M. C.; Suh, P. K.

    1979-01-01

    Large Space Systems (LSS) comprise a new class of spacecraft, the design and performance of which may be seriously affected by a variety of environmental interactions. The special concerns associated with spacecraft charging and plasma interactions from the LSS designer's viewpoint are addressed. Survivability of these systems under combined solar U.V., particle radiation and repeated electrical discharges is of primary importance. Additional questions regard the character of electrical discharges over very large areas, the effects of high current/voltage systems and magnitude of induced structural disturbances. A concept is described for a large scale experiment platform.

  8. Space Weather data processing and Science Gateway for the Van Allen Probes

    NASA Astrophysics Data System (ADS)

    Romeo, G.; Barnes, R. J.; Weiss, M.; Fox, N. J.; Mauk, B.; Potter, M.; Kessel, R.

    2013-12-01

    A near real-time data processing pipeline for the Space Weather broadcast data from the Van Allen Probes is presented. The Van Allen Probes broadcasts a sub-set of the science data in real-time when not downlinking the principal science data. This broadcast is received by several ground stations and relayed to APL in near real time to be ingested into the space weather processing pipeline. This pipeline processes the available level zero space weather data into higher level science data products. These products are made available to the public via the Van Allen Probes Science Gateway website (http://athena.jhuapl.edu). The website acts as pivotal point though which all other instrument SOC's can be accessed. Several other data products (e.g KP/DST indices) and tools (e.g orbit calculator) are made also available to the general public.

  9. The Future of NASA's Deep Space Network and Applications to Planetary Probe Missions

    NASA Technical Reports Server (NTRS)

    Deutsch, Leslie J.; Preston, Robert A.; Vrotsos, Peter

    2010-01-01

    NASA's Deep Space Network (DSN) has been an invaluable tool in the world's exploration of space. It has served the space-faring community for more than 45 years. The DSN has provided a primary communication pathway for planetary probes, either through direct- to-Earth links or through intermediate radio relays. In addition, its radiometric systems are critical to probe navigation and delivery to target. Finally, the radio link can also be used for direct scientific measurement of the target body ('radio science'). This paper will examine the special challenges in supporting planetary probe missions, the future evolution of the DSN and related spacecraft technology, the advantages and disadvantages of radio relay spacecraft, and the use of the DSN radio links for navigation and scientific measurements.

  10. MARINER 8 SPACE PROBE'S SOLAR ARRAYS ARE INSTALLED

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Technicians prepare to install a solar panel on the Mariner H spacecraft in preparation for its launch to Mars, no earlier than May 7, 1971. The spacecraft will be launched aboard an Atlas Centaur space vehicle from Cape Kennedy's Complex 36A, and will go into orbit around Mars at the completion of a seven-month journey from Earth. It is designed to operate 90 days and return data about the planet's atmospheric and surface characteristics. Following launch, the spacecraft will be designated Mariner 8. A second Mariner Mars spacecraft is scheduled to be launched 10 days later.

  11. MARINER 8 SPACE PROBE UNDERGOES INSTALLATION OF SOLAR ARRAYS

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Technicians install solar panels aboard the mariner H spacecraft in a cleanroom facility at Cape Kennedy. The spacecraft will orbit Mars following a seven-month journey from Earth. Designed to function 90 days, the spacecraft, which will be designated Mariner 8 following launch, will provide data about the Red Planet's atmospheric and surface characteristics. Mariner Mars H will be launched aboard an Atlas-Centaur space vehicle no earlier than May 7, 1971, from Cape Kennedy's Launch Complex 36A. A second Mariner Mars spacecraft will be launched 10 days later.

  12. Space probe/satellite ejection apparatus for spacecraft

    NASA Technical Reports Server (NTRS)

    Smyly, H. M.; Miller, C. D.; Cloyd, R. A.; Heller, C. (Inventor)

    1984-01-01

    An ejection apparatus for spinning and propelling objects for ejection from a spacecraft at a desired velocity and rotational speed is discussed. The apparatus includes a launch cradle on which the space object to be ejected rests. The cradle is rotatably supported by a central hub secured to the upper end of the pneumatic cylinder piston shaft. Release mechanisms consisting of a retractable pin and locking lug is utilized to hold the cradle and object to be ejected. The release mechanism has a fixed barrier member which holds the retractable pin in engagement with the locking lug until release by upward movement of the launch cradle beyond the barrier height.

  13. Space probe/satellite ejection apparatus for spacecraft

    NASA Technical Reports Server (NTRS)

    Smyly, H. M.; Miller, C. D.; Cloyd, R. A.; Heller, C. (Inventor)

    1985-01-01

    An ejection apparatus for spinning and propelling objects for ejection from a spacecraft at a desired velocity and rotational speed is discussed. The apparatus includes a launch cradle on which the space object to be ejected rests. The cradle is rotatably supported by a central hub secured to the upper end of the pneumatic cylinder piston shaft. Release mechanisms consisting of a retractable pin and locking lug is utilized to hold the cradle and object to be ejected. The release mechanism has a fixed barrier member which holds the retractable pin in engagement with the locking lug until release by upward movement of the launch cradle beyond the barrier height.

  14. Photonic probing of radio waves for k-space tomography.

    PubMed

    Murakowski, Janusz; Schneider, Garrett J; Shi, Shouyuan; Schuetz, Christopher A; Prather, Dennis W

    2017-07-10

    We harness coherent optical processing to simultaneously sense the angle of arrival and the frequency of radio waves. Signals captured by a distributed antenna array are up-converted to optical domain using electro-optic modulators coupled to individual antennas. Employing a common laser source to feed all the modulators ensures spatially coherent up-conversion of radio-frequency (RF) waves to optical beams carried by optical fibers. Fiber-length dispersion extends the spatial aperture of the distributed antenna array into the temporal dimension. The interference of beams emanating from the fibers is captured by a CCD and used to computationally reconstruct RF waves in k-space.

  15. Astrometric Gravitation Probe: a space mission concept for fundamental physics

    NASA Astrophysics Data System (ADS)

    Vecchiato, Alberto; Fienga, Agnes; Gai, Mario; Lattanzi, Mario G.; Riva, Alberto; Busonero, Deborah

    2015-08-01

    Modern technological developments have pushed the accuracy of astrometric measurements in the visible band down to the micro-arcsec level. This allows to test theories of gravity in the weak field limit to unprecedented level, with possible consequences spanning from the validity of fundamental physics principles, to tests of theories describing cosmological and galactic dynamics without resorting to Dark Matter and Dark Energy.This is the main goal of Astrometric Gravitation Probe (AGP) mission, which will be achieved by highly accurate astrometric determination of light deflection (as a modern rendition of the Dyson, Eddington, and Robertson eclipse experiment of 1919), aberration, and of the orbits of selected Solar System objects, with specific reference to the excess shift of the pericentre effect.The AGP concept was recently proposed for the recent call for ESA M4 missions as a collaboration among several scientists coming from many different European and US institutions. Its payload is based on a 1.15 m diameter telescope fed through a coronagraphic system by four fields, two set in symmetric positions around the Sun, and two in the opposite direction, all imaged on a CCD detector. Large parts of the instrument are common mode to all fields. The baseline operation mode is the scan of the ±1.13 deg Ecliptic strip, repeated for a minimum of 3 years and up to an optimal duration of 5 years. Operations and calibrations are simultaneous, defined in order to ensure common mode instrumental effects, identified and removed in data reduction. The astrometric and coronagraphic technologies build on the heritage of Gaia and Solar Orbiter.We review the mission concept and its science case, and discuss how this measurement concepts can be scaled to different mission implementations.

  16. Pu-powered space probes face uncertain future

    SciTech Connect

    1994-10-01

    When fragments of comet Shoemaker-Levy 9 crashed into the gas clouds of Jupiter in July, the only representatives of humankind with a good view were a trio of spacecraft, Voyager 2, Galileo, and Ulysses. Radioisotope thermoelectric generators (RTGs) supplied by the Department of Energy provided the power to run the observing instruments on these spacecraft, but now that source of power-and all deep-space missions-may be in jeopardy. Despite the fact that the recently passed congressional appropriations bill increased funding for the RTG program by nearly 20 percent, from $51 million in 1994 to $61 million in 1995, rumors persist that the program is in danger of being discontinued. Peter Ulrich, chief of the Flight Programs Branch of the Solar System Exploration Division of the Office of Space Science at NASA, was confident that the program would stay alive through NASA`s next mission. RTGs will be on board the Cassini spacecraft scheduled to blast off in 1997 for an exploration of Saturn and its rings and moons. RTG`s use the heat produced by the alpha decay of plutonium-238 to heat a thermocouple, which generates electricity. Cassini is designed to carry three RTGs, producing a total of 750 W of electricity initially, decreasing to about 600 W by the time it reaches Saturn seven years after launch. The RTGs on Cassini will carry a total of about 70 lb of plutonium oxide. RTGs have no moving parts. They are simple, rugged, and reliable. According to Ulrich, {open_quotes}It`s really a very well-matched power source for something like a remote mission.{close_quotes} The political situation is less clear, though. {open_quotes}What I hear unofficially is funding looks dime,{close_quotes} said the DOE spokesperson, {open_quotes}and the lights are being turned off for these missions.{close_quotes} If that happens, the lights will go out on NASA`s deep-space missions to other parts of our solar system.

  17. Space climate implications from substorm frequency

    NASA Astrophysics Data System (ADS)

    Newell, P. T.; Gjerloev, J. W.; Mitchell, E. J.

    2013-10-01

    solar wind impacting the Earth varies over a wide range of time scales, driving a corresponding range of geomagnetic activity. Past work has strongly indicated that the rate of merging on the frontside magnetosphere is the most important predictor for magnetospheric activity, especially over a few hours. However, the magnetosphere exhibits variations on other time scales, including UT, seasonal, and solar cycle variations. Much of this geomagnetic variation cannot be reasonably attributed to changes in the solar wind driving—that is, it is not created by the original Russell-McPherron effect or any generalization thereof. In this paper we examine the solar cycle, seasonal, and diurnal effects based upon the frequency of substorm onsets, using a data set of 53,000 substorm onsets. These were identified through the SuperMAG collaboration and span three decades with continuous coverage. Solar cycle variations include a profound minimum in 2009 (448 substorms) and peak in 2003 (3727). The magnitude of this variation (a factor of 8.3) is not explained through variations in estimators of the frontside merging rate (such as dΦMP/dt), even when the more detailed probability distribution functions are examined. Instead, v, or better, n1/2v2 seems to be implicated in the dramatic difference between active and quiet years, even beyond the role of velocity in modulating merging. Moreover, we find that although most substorms are preceded by flux loading (78.5% are above the mean and 83.8% above median solar wind driving), a high solar wind v is almost as important (68.3% above mean, 74.8% above median). This and other evidence suggest that either v or n1/2v2 (but probably not p) plays a strong secondary role in substorm onset. As for the seasonal and diurnal effects, the elliptical nature of the Earth's orbit, which is closest to the Sun in January, leads to a larger solar wind driving (measured by Bs, vBs, or dΦMP/dt) in November, as is confirmed by 22 years of solar wind

  18. NASA's Van Allen Probes Spot an Impenetrable Barrier in Space

    NASA Image and Video Library

    2017-09-28

    Two donuts of seething radiation that surround Earth, called the Van Allen radiation belts, have been found to contain a nearly impenetrable barrier that prevents the fastest, most energetic electrons from reaching Earth. Read more: 1.usa.gov/11v7nUW Caption: This is a visualization of the radiation belts with confined charged particles (blue & yellow) and plasmapause boundary (blue-green surface) Caption: NASA's Scientific Visualization Studio NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  19. Welded Titanium Case for Space-Probe Rocket Motor

    NASA Technical Reports Server (NTRS)

    Brothers, A. J.; Boundy, R. A.; Martens, H. E.; Jaffe, L. D.

    1959-01-01

    Early in 1958, the Jet Propulsion Laboratory of the California Institute of Technology was requested to participate in a lunar-probe mission code-named Juno II which would place a 15-lb Instrumented payload (Pioneer IV) in the vicinity of the moon. The vehicle was to use the same high-speed upper-stage assembly as flown on the successful Jupiter-C configuration; however, the first-stage booster was to be a Jupiter rather than a Redstone. An analysis of the intended flight and payload configuration Indicated that the feasibility of accomplishing the mission was questionable and that additional performance would have to be obtained if the mission was to be feasible. Since the most efficient way of Increasing the performance of a staged vehicle is to increase the performance of the last stage, a study of possible ways of doing this was made.. Because of the time schedule placed on this effort It was decided to reduce the weight of the fourth-stage rocket-motor case by substituting the annealed 6Al--4V titanium alloy for the Type 410 stainless steel. Although this introduced an unfamiliar material, It reduced the changes in design and fabrication techniques. This particular titanium alloy was chosen on the basis of previous tests which proved the suitability of the alloy as a pressure-vessel material when used at an annealed yield strength of about 120, 000 psi. The titanium-case fourth stage of Juno U is shown with the payload and on the missile in Fig. 1; the stainless-steel motor cases used in the Jupiter-C vehicle are shown in Fig. 2. The fourth-stage motor case has a diameter of 6 in., a length of approximately 38 in. center dot and a nominal cylindrical wall thickness of 0.025 in. As shown in Fig. 1, the case serves as the structural support of the payload and is aligned to the upper stage assembly through an alignment ring. The nozzle is threaded into the end of the motor case, and is of the ceramic-coated steel design. Figure 3 shows a comparison of the

  20. Means to remove electrode contamination effect of Langmuir probe measurement in space

    SciTech Connect

    Oyama, K.-I.; Lee, C. H.; Fang, H. K.; Cheng, C. Z.

    2012-05-15

    Precaution to remove the serious effect of electrode contamination in Langmuir probe experiments has not been taken in many space measurements because the effect is either not understood or ignored. We stress here that one should pay extra attention to the electrode contamination effect to get accurate and reliable plasma measurements so that the long time effort for sounding rocket/satellite missions does not end in vain or becomes less fruitful. In this paper, we describe two main features of voltage-current characteristic curves associated with the contaminated Langmuir probe, which are predicted from the equivalent circuit model, which we proposed in 1970's. We then show that fast sweeping dc Langmuir probes can give reliable results in the steady state regime. The fast sweeping probe can also give reliable results in transient situations such as satellite moves through plasma bubble in the ionosphere where the electron density drastically changes. This fact was first confirmed in our laboratory experiment.

  1. Means to remove electrode contamination effect of Langmuir probe measurement in space.

    PubMed

    Oyama, K-I; Lee, C H; Fang, H K; Cheng, C Z

    2012-05-01

    Precaution to remove the serious effect of electrode contamination in Langmuir probe experiments has not been taken in many space measurements because the effect is either not understood or ignored. We stress here that one should pay extra attention to the electrode contamination effect to get accurate and reliable plasma measurements so that the long time effort for sounding rocket/satellite missions does not end in vain or becomes less fruitful. In this paper, we describe two main features of voltage-current characteristic curves associated with the contaminated Langmuir probe, which are predicted from the equivalent circuit model, which we proposed in 1970's. We then show that fast sweeping dc Langmuir probes can give reliable results in the steady state regime. The fast sweeping probe can also give reliable results in transient situations such as satellite moves through plasma bubble in the ionosphere where the electron density drastically changes. This fact was first confirmed in our laboratory experiment.

  2. Means to remove electrode contamination effect of Langmuir probe measurement in space

    NASA Astrophysics Data System (ADS)

    Oyama, K.-I.; Lee, C. H.; Fang, H. K.; Cheng, C. Z.

    2012-05-01

    Precaution to remove the serious effect of electrode contamination in Langmuir probe experiments has not been taken in many space measurements because the effect is either not understood or ignored. We stress here that one should pay extra attention to the electrode contamination effect to get accurate and reliable plasma measurements so that the long time effort for sounding rocket/satellite missions does not end in vain or becomes less fruitful. In this paper, we describe two main features of voltage-current characteristic curves associated with the contaminated Langmuir probe, which are predicted from the equivalent circuit model, which we proposed in 1970's. We then show that fast sweeping dc Langmuir probes can give reliable results in the steady state regime. The fast sweeping probe can also give reliable results in transient situations such as satellite moves through plasma bubble in the ionosphere where the electron density drastically changes. This fact was first confirmed in our laboratory experiment.

  3. Launch summary for 1978 - 1982. [sounding rockets, space probes, and satellites

    NASA Technical Reports Server (NTRS)

    Hills, H. K.

    1984-01-01

    Data pertinent to the launching of space probes, soundings rockets, and satellites presented in tables include launch date, time, and site; agency rocket identification; sponsoring country or countries; instruments carried for experiments; the peak altitude achieved by the rockets; and the apoapsis and periapsis for satellites. The experimenter or institution involved in the launching is also cited.

  4. Simulating satellite and space probe motion at high school with spreadsheets

    NASA Astrophysics Data System (ADS)

    Benacka, Jan

    2017-01-01

    This paper gives an account of an experiment in which thirty-three high school students of ages 17-19 developed spreadsheet numerical models of satellite and space probe motion. The models are free to download. A survey was carried out to find out the students’ opinion of the lessons.

  5. Deep Space Chronicle: A Chronology of Deep Space and Planetary Probes 1958-2000

    NASA Technical Reports Server (NTRS)

    Siddiqi, Asif A.; Launius, Roger (Technical Monitor)

    2002-01-01

    This monograph contains brief descriptions of all robotic deep space missions attempted since the opening of the space age in 1957. The missions are listed strictly chronologically in order of launch date (not by planetary encounter).

  6. The space charge layer of the electrical probe taking into account the collisions

    NASA Astrophysics Data System (ADS)

    Sysun, V. I.; Ignakhin, V. S.

    2017-08-01

    The space charge layer of a cylindrical probe has been considered under moderate pressures. A precise solution of Poisson's equation has been obtained in the approximation of strong field taking into account collisions with atoms. The approximate expression for a space charge layer in the cylindrical geometry without collisions has been suggested; the expression yields an error of up to 1% at 1 ≤ r_{sh}/r_p ≤ 200. A simplified approximate expression for a space charge layer under moderate pressures, which is suitable for practical calculations, has also been proposed.

  7. The Space High Angular Resolution Probe for the Infrared (SHARP-IR)

    NASA Technical Reports Server (NTRS)

    Rinehart, S. A.; Rizzo, M. J.; Leisawitz, D. T.; Staguhn, J. G.; Dipirro, M.; Mentzell, J. E.; Juanola-Parramon, R.; Dhabal, A.; Mundy, L. G.; Moseley, S. H.; hide

    2016-01-01

    The Space High Angular Resolution Probe for the Infrared (SHARP-IR) is a new mission currently under study. As partof the preparation for the Decadal Survey, NASA is currently undertaking studies of four major missions, but interesthas also been shown in determining if there are feasible sub-$1B missions that could provide significant scientific return.SHARP-IR is being designed as one such potential probe. In this talk, we will discuss some of the potential scientificquestions that could be addressed with the mission, the current design, and the path forward to concept maturation.

  8. The Deep Space Network. An instrument for radio navigation of deep space probes

    NASA Technical Reports Server (NTRS)

    Renzetti, N. A.; Jordan, J. F.; Berman, A. L.; Wackley, J. A.; Yunck, T. P.

    1982-01-01

    The Deep Space Network (DSN) network configurations used to generate the navigation observables and the basic process of deep space spacecraft navigation, from data generation through flight path determination and correction are described. Special emphasis is placed on the DSN Systems which generate the navigation data: the DSN Tracking and VLBI Systems. In addition, auxiliary navigational support functions are described.

  9. Expanding Box simulations: implications the Solar Probe Plus and Solar Orbiter missions.

    NASA Astrophysics Data System (ADS)

    Verdini, A.

    2014-12-01

    Recent three-dimensional simulations in the Expanding Box Model (EBM) show how the radial evolution of the spectral anisotropy of turbulence depends on the unknown coronal spectrum. However, regardless of the source spectrum, the solar wind expansion causes 1) the emergence of microstream structures and 2) a well defined component anisotropy.I will discuss the implications of such findings for the expected turbulent spectrum in the inner heliosphere and for the identification of microstreams in Solar Probe Plus records. I will also show how the EBM can be used to cross-check the 1D spectrum and to get insights on the unknown 3D structure of turbulence during radial alignment configurations of Solar Orbiter and Solar Probe Plus.

  10. Microgravity and immune responsiveness: implications for space travel.

    PubMed

    Borchers, Andrea T; Keen, Carl L; Gershwin, M Eric

    2002-10-01

    To date, several hundred cosmonauts and astronauts have flown in space, yet knowledge about the adaptation of their immune system to space flight is rather limited. It is evident that a variety of immune parameters are changed during and after space flight, but the magnitude and pattern of these changes can differ dramatically between missions and even between crew members on the same mission. A literature search was conducted involving a total of 335 papers published between 1972 and 2002 that dealt with the key words immune response, microgravity and astronauts/cosmonauts, isolation, gravity, and human health. The data from multiple studies suggested that major discrepancies in outcome are due to methodologic differences. However, the data also suggested major factors that affect and modulate the immune response during space travel. In part at least, these discrepancies can be attributed to methodologic differences. In addition, a variety of other features, in particular the types and extent of stressors encountered during space missions, are likely to contribute to the variability of immune responses during and after space flight. That stress plays an important role in the effects of space flight on immunologic parameters is suggested by the frequent findings that stress hormones are upregulated during and after space flight. Unfortunately, however, the existing data on hormonal parameters are almost as varied as those on immunologic changes, and correlations between the two datasets have only rarely been attempted. The functional implications of space flight-induced alterations in immune response largely remain to be elucidated, but the data suggest that long-term travel will be associated with the development of immune-compromised hosts.

  11. Investigation of interplanetary dust from out-of-ecliptic space probes. [astronomical models of interplanetary dust

    NASA Technical Reports Server (NTRS)

    Fechtig, H.; Giese, R. H.; Hanner, M. S.; Zook, H. A.

    1976-01-01

    Measurements of interplanetary dust via zodiacal light observations and direct detection are discussed for an out-of-ecliptic space probe. Particle fluxes and zodiacal light brightnesses were predicted for three models of the dust distribution. These models predict that most of the information will be obtained at space probe distances less than 1 A.U. from the ecliptic plane. Joint interpretation of the direct particle measurements and the zodiacal light data can yield the best knowledge of the three-dimensional particle dynamics, spatial distribution, and physical characteristics of the interplanetary dust. Such measurements are important for an understanding of the origin and role of the dust in relation to meteoroids, asteroids, and comets, as well as the interaction of the dust with solar forces.

  12. On the detection of a cometary mass distribution. [by perturbations on space probe orbits

    NASA Technical Reports Server (NTRS)

    Boss, A. P.; Peale, S. J.

    1976-01-01

    The problem of detecting a possible cometary distribution on the fringes of the solar system is examined. The acceleration of a space probe due to a hypothetical cometary mass distribution with the surface density rising to a maximum and subsequently falling off with increasing distance from the sun is analyzed. The total minimum detectable cometary mass for the Pioneer and Mariner spacecraft is estimated on the basis of this model to be on the order of 1000 earth masses. Precision tracking of deep space probes is less sensitive by three orders of magnitude for the detection of an unseen cometary mass distribution at the fringes of the solar system than are the secular perturbations of long-period comets.

  13. Physical limitations in sensors for a drag-free deep space probe

    NASA Technical Reports Server (NTRS)

    Juillerat, R.

    1971-01-01

    The inner perturbing forces acting on sensors were analyzed, taking into account the technological limitations imposed on the proof mass position pickup and proof mass acquisition system. The resulting perturbing accelerations are evaluated as a function of the drag-free sensor parameters. Perturbations included gravitational attraction, electrical action, magnetic action, pressure effects, radiation effects, and action of the position pickup. These data can be used to study the laws of guidance, providing an optimization of the space probe as a whole.

  14. Physical limitations in sensors for a drag-free deep space probe

    NASA Technical Reports Server (NTRS)

    Juillerat, R.

    1971-01-01

    The inner perturbing forces acting on sensors were analyzed, taking into account the technological limitations imposed on the proof mass position pickup and proof mass acquisition system. The resulting perturbing accelerations are evaluated as a function of the drag-free sensor parameters. Perturbations included gravitational attraction, electrical action, magnetic action, pressure effects, radiation effects, and action of the position pickup. These data can be used to study the laws of guidance, providing an optimization of the space probe as a whole.

  15. Cosmological Implications of the First Year Wilkinson Microwave Anisotropy Probe Results

    NASA Astrophysics Data System (ADS)

    Verde, L.

    The Wilkinson Microwave Anisotropy Probe (WMAP) team has recently analyzed and released the first-year data. We will review the implications for cosmology of these results. The highlight is that cosmology now has a standard cosmological model. With only 6 parameters the model fits not only WMAP data remarkably well, but also a host of other astronomical observations. We also present the results on neutrino mass limits and on dark energy properties from a joint likelihood analysis of WMAP data with small-scale CMB experiments and large-scale structure surveys. The data and supplementary information are publicly available and can be found on the experiment web site at .

  16. Modulating molecular level space proximity: a simple and efficient strategy to design structured DNA probes.

    PubMed

    Zheng, Jing; Li, Jishan; Gao, Xiaoxia; Jin, Jianyu; Wang, Kemin; Tan, Weihong; Yang, Ronghua

    2010-05-01

    To construct efficient oligonucleotide probes, specific nucleic acid is designed as a conformationally constrained form based on the formation of a Watson-Crick-based duplex. However, instability of Watson-Crick hydrogen bonds in a complex biological environment usually leads to high background signal from the probe itself and false positive signal caused by nonspecific binding. To solve this problem, we propose a way to restrict the labeled-dyes in a hydrophobic cavity of cyclodextrin. This bounding, which acts like extra base pairs to form the Watson-Crick duplex, achieves variation of level of space proximity of the two labels and thus the degree of conformational constraint. To demonstrate the feasibility of the design, a stem-containing oligonucleotide probe (P1) for DNA hybridization assay and a stemless one (P2) for protein detection were examined as models. Both oligonucleotides were doubly labeled with pyrene at the 5'- and 3'- ends, respectively. It is the cyclodextrin/pyrene inclusion interaction that allows modulating the degree of conformational constraints of P1 and P2 and thus their background signals and selectivity. Under the optimal conditions, the ratio of signal-to-background of P1/gamma-CD induced by 1.0 equiv target DNA is near 174, which is 4-fold higher than that in the absence of gamma-CD. In addition, the usage of gamma-CD shifts the melting temperature of P1 from 57 to 68 degrees C, which is reasonable for improving target-binding selectivity. This approach is simple in design, avoiding any variation of the stem's length and sequences. Furthermore, the strategy is generalizable which is suited for not only the stem-containing probe but also the linear probe with comparable sensitivity and selectivity to conventional structured DNA probes.

  17. The deep space network. [tracking and communication support for space probes

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The objectives, functions, and organization of the deep space network are summarized. Progress in flight project support, tracking and data acquisition research and technology, network engineering, hardware and software implementation, and operations is reported. Interface support for the Mariner Venus Mercury 1973 flight and Pioneer 10 and 11 missions is included.

  18. Legal Implications of Military Uses of Outer Space

    NASA Astrophysics Data System (ADS)

    Catena, Johanna

    2002-01-01

    Acquisition of Space Weapons, the Legal, Political and Military Impact for International Peace and At the dawn of a new century an immediate danger is upon us: The weaponization of outer space, including potential cost implications upon the prospect of ushering an era of peace and prosperity. But, can such statements be explained as pure sentimentality for hopes of a new era? Or is the danger misplaced that the threat to peace and security is an ever more ominous? By militarising outer space one could monitor crisis areas that could become a potential threat and this would in turn build confidence and security amongst nations. However the Outer Space Treaty prohibits placing in orbit nuclear and other weapons of mass destruction. This does not include other military systems. Many countries feel the prohibition should be extended in the Treaty. Other military systems may involve anti-satellite weapons, (ASATS), emitting or simply placing technologies in space using laser and /or particle beams from space to intercept presently specific military targets such as ballistic missiles and hostile satellites, but in the future this may extend to destroying a target on earth. Military presence in space however, is not founded on weapons alone, but also through military surveillance systems and seen by some countries as an effective measure in verification on arms control. It is also seen as intensifying an arms race. At the forefront of the debate for space weapons is the possibility of countries deploying a National Missile Defence system. How does one reconcile such a system with present treaties? There has always been a direct relationship between weapons and space exploration, particularly if traced through the history of the late nineteenth century to the era of the space race. Konstantin Tsiolkovsky, (1857 - 1935), was one of the founders to astronautics. Robert Goddard, (1882-1945) an Englishman, developed Tsiolkovskys' work further. He built the first liquid

  19. CIM in space: Corporate Information Management (CIM) implications for space-based information systems

    NASA Astrophysics Data System (ADS)

    Mock, Richard V.

    1993-04-01

    This paper describes the DOD corporate information management (CIM) initiative, space forces, and space-based information systems used by the DOD. It then describes implications of CIM in the space industry. CIM is defined as a philosophy which has management and technical components. The CIM management philosophy includes concepts for standardization, system engineering, and the use of commercial systems and technology. The technical component uses the information engineering discipline to improve business processes. The paper provides examples of the CIM management philosophy in operation as well as opportunities for CIM application. Information engineering is described as it applies to space-based information systems. The appendix includes an illustrative example of the integrated definition (IDEF) methodology applied to the tactical warning/attack assessment mission.

  20. Operational Capabilities and Legal Implications of a Military Space Plane

    NASA Astrophysics Data System (ADS)

    Charania, A.

    2002-01-01

    The potential challenges for the United States military in this upcoming century may require new types of capabilities only achievable through the application of new technologies. One of these potential capabilities includes a Military Space Plane (MSP). An MSP is a concept to use reusable launch vehicle (RLV) technologies in a system to provide the military global access and reach in a timely fashion that could be operational within a decade. New awareness is evident from both recent federal commission reports and activities in Afghanistan of the military's possible use of such capabilities to provide asymmetric advantages. The MSP may eventually become part of a new spaceforce that coordinates the broad range of defensive and offensive space assets. In addition, a new emphasis is being placed upon NASA and the U.S. Air Force to coordinate activity on such a space plane/RLV development. The interaction of civilian and defense agencies for such a program has ramifications, not just in terms of the requirements on a final operational vehicle, but also on the legal charters of both entities. This examination presents operational scenarios for a military space plane in order to derive various legal implications.

  1. Culture and error in space: implications from analog environments.

    PubMed

    Helmreich, R L

    2000-09-01

    An ongoing study investigating national, organizational, and professional cultures in aviation and medicine is described. Survey data from 26 nations on 5 continents show highly significant national differences regarding appropriate relationships between leaders and followers, in group vs. individual orientation, and in values regarding adherence to rules and procedures. These findings replicate earlier research on dimensions of national culture. Data collected also isolate significant operational issues in multi-national flight crews. While there are no better or worse cultures, these cultural differences have operational implications for the way crews function in an international space environment. The positive professional cultures of pilots and physicians exhibit a high enjoyment of the job and professional pride. However, a negative component was also identified characterized by a sense of personal invulnerability regarding the effects of stress and fatigue on performance. This misperception of personal invulnerability has operational implications such as failures in teamwork and increased probability of error. A second component of the research examines team error in operational environments. From observational data collected during normal flight operations, new models of threat and error and their management were developed that can be generalized to operations in space and other socio-technological domains. Five categories of crew error are defined and their relationship to training programs in team performance, known generically as Crew Resource Management, is described. The relevance of these data for future spaceflight is discussed.

  2. Space pruning monotonic search for the non-unique probe selection problem.

    PubMed

    Pappalardo, Elisa; Ozkok, Beyza Ahlatcioglu; Pardalos, Panos M

    2014-01-01

    Identification of targets, generally viruses or bacteria, in a biological sample is a relevant problem in medicine. Biologists can use hybridisation experiments to determine whether a specific DNA fragment, that represents the virus, is presented in a DNA solution. A probe is a segment of DNA or RNA, labelled with a radioactive isotope, dye or enzyme, used to find a specific target sequence on a DNA molecule by hybridisation. Selecting unique probes through hybridisation experiments is a difficult task, especially when targets have a high degree of similarity, for instance in a case of closely related viruses. After preliminary experiments, performed by a canonical Monte Carlo method with Heuristic Reduction (MCHR), a new combinatorial optimisation approach, the Space Pruning Monotonic Search (SPMS) method, is introduced. The experiments show that SPMS provides high quality solutions and outperforms the current state-of-the-art algorithms.

  3. ULF Waves Observed at MAGDAS Stations as Probes for Litho-Space Weather Study

    NASA Astrophysics Data System (ADS)

    Yumoto, Kiyohumi

    K.Yumoto, Space Environment Research Center (SERC), Kyushu University started the MAGDAS Project effectively in May of 2005, with the installation of the first unit in Hualien, Taiwan (Yumoto et al., 2006, 2007). Since then, over 50 units have been deployed around the world. They are concentrated along three chains: (1) North and South of Japan (the so-called "210o Magnetic Meridian Chain"), (2) Dip Equator Chain, and (3) Africa Chain (the so-called "96o Magnetic Meridian Chain"). The main goals of MAGDAS project are: (1) study magnetospheric pro-cesses by distinguishing between temporal changes and spatial variations in the phenomena, (2) clarify global structures and propagation characteristics of magnetospheric variations from higher to equatorial latitudes, and (3) understand global generation mechanisms of the Solar-Terrestrial phenomena (see Yumoto, 2004). From MAGDAS observations, ULF waves are found to be used as good probes for litho-space weather study in developing and developed countries. In the present paper, we will introduce the following examples: Pc 5 magnetic amplitudes at lower-latitude MAGDAS station show a linear relation with the solar wind velocity, thus we can use the Pc 5 amplitudes as a monitoring probe of the solar wind velocity. Pc 3-4 magnetic pulsations have skin depth comparable with the depth of epicentre of earthquakes in the lithosphere. Therefore, we can use Pc 3-4 as a probe for detecting ULF anomaly and precursors associated with great earthquakes. Pi 2 magnetic pulsations are observed globally at MAGDAS stations located at high, middle, low, and equatorial latitudes in night-and day-time. We can use the Pi 2s as a good indicator of onsets of magnetospheric substorms. Sudden commencements (sc), sudden impulse (si), and solar flare effects (sfe) create magnetic variations at MAGDAS stations. Therefore, MAGDAS data can be used as a probe of interplanetary shocks and interplanetary discontinuities in the solar wind, and solar flare

  4. Science with the space-based interferometer LISA. IV: probing inflation with gravitational waves

    NASA Astrophysics Data System (ADS)

    Bartolo, Nicola; Caprini, Chiara; Domcke, Valerie; Figueroa, Daniel G.; Garcia-Bellido, Juan; Chiara Guzzetti, Maria; Liguori, Michele; Matarrese, Sabino; Peloso, Marco; Petiteau, Antoine; Ricciardone, Angelo; Sakellariadou, Mairi; Sorbo, Lorenzo; Tasinato, Gianmassimo

    2016-12-01

    We investigate the potential for the LISA space-based interferometer to detect the stochastic gravitational wave background produced from different mechanisms during inflation. Focusing on well-motivated scenarios, we study the resulting contributions from particle production during inflation, inflationary spectator fields with varying speed of sound, effective field theories of inflation with specific patterns of symmetry breaking and models leading to the formation of primordial black holes. The projected sensitivities of LISA are used in a model-independent way for various detector designs and configurations. We demonstrate that LISA is able to probe these well-motivated inflationary scenarios beyond the irreducible vacuum tensor modes expected from any inflationary background.

  5. Implications of Responsive Space on the Flight Software Architecture

    NASA Technical Reports Server (NTRS)

    Wilmot, Jonathan

    2006-01-01

    The Responsive Space initiative has several implications for flight software that need to be addressed not only within the run-time element, but the development infrastructure and software life-cycle process elements as well. The runtime element must at a minimum support Plug & Play, while the development and process elements need to incorporate methods to quickly generate the needed documentation, code, tests, and all of the artifacts required of flight quality software. Very rapid response times go even further, and imply little or no new software development, requiring instead, using only predeveloped and certified software modules that can be integrated and tested through automated methods. These elements have typically been addressed individually with significant benefits, but it is when they are combined that they can have the greatest impact to Responsive Space. The Flight Software Branch at NASA's Goddard Space Flight Center has been developing the runtime, infrastructure and process elements needed for rapid integration with the Core Flight software System (CFS) architecture. The CFS architecture consists of three main components; the core Flight Executive (cFE), the component catalog, and the Integrated Development Environment (DE). This paper will discuss the design of the components, how they facilitate rapid integration, and lessons learned as the architecture is utilized for an upcoming spacecraft.

  6. Cosmological Implications of the First Year Wilkinson Microwave Anisotropy Probe Results

    NASA Astrophysics Data System (ADS)

    Verde, L.

    2004-02-01

    The Wilkinson Microwave Anisotropy Probe (WMAP) team has recently analyzed and released the first-year data. We will review the implications for cosmology of these results. The highlight is that cosmology now has a standard cosmological model. With only 6 parameters the model fits not only WMAP data remarkably well, but also a host of other astronomical observations. We also present the results on neutrino mass limits and on dark energy properties from a joint likelihood analysis of WMAP data with small-scale CMB experiments and large-scale structure surveys. The data and supplementary information are publicly available and can be found on the experiment web site at .

  7. On the Transfer and Control of Space Probes Around the L1 Point of the Sun-Earth+Moon System

    NASA Astrophysics Data System (ADS)

    Hou, Xi-Yun; Liu, Lin

    2008-01-01

    The motion around the collinear libration points in the restricted three body problem is unstable. But there exist conditionally stable periodic orbits around these points. Special-purpose space probes located in the vicinity of these points (e.g., ISEE-3, SOHO) can benefit from this dynamical property, in regard to maintaining the orbit in position and the energy required of placing the probe in position. As an example, we study in this paper the launch and orbital control of a space probe around the L1 libration point in the system consisting of the Sun and the Earth-Moon. We present some theoretical and numerical simulations' results, which may serve as a basis for the realization of such a space probe in future.

  8. Van Allen Probes Mission Space Academy: Educating middle school students about Earth's mysterious radiation belts

    NASA Astrophysics Data System (ADS)

    Butler, L.; Turney, D.; Matiella Novak, A.; Smith, D.; Simon, M.

    2013-12-01

    How's the weather in space? Why on Earth did NASA send two satellites above Earth to study radiation belts and space weather? To learn the answer to questions about NASA's Van Allen Probes mission, 450 students and their teachers from Maryland middle schools attended Space Academy events highlighting the Van Allen Probes mission. Sponsored by the Applied Physics Laboratory (APL) and Discovery Education, the events are held at the APL campus in Laurel, MD. Space Academies take students and teachers on behind-the-scenes exploration of how spacecraft are built, what they are designed to study, and introduces them to the many professionals that work together to create some of NASA's most exciting projects. Moderated by a public relations representative in the format of an official NASA press conference, the daylong event includes a student press conference with students as reporters and mission experts as panelists. Lunch with mission team members gives students a chance to ask more questions. After lunch, students don souvenir clean room suits, enjoy interactive science demonstrations, and tour APL facilities where the Van Allen Probes were built and tested before launch. Students may even have an opportunity to peek inside a clean room to view spacecraft being assembled. Prior to the event, teachers are provided with classroom activities, lesson plans, and videos developed by APL and Discovery Education to help prepare students for the featured mission. The activities are aligned to National Science Education Standards and appropriate for use in the classroom. Following their visit, student journalists are encouraged to write a short article about their field trip; selections are posted on the Space Academy web site. Designed to engage, inspire, and influence attitudes about space science and STEM careers, Space Academies provide an opportunity to attract underserved populations and emphasize that space science is for everyone. Exposing students to a diverse group of

  9. Space-resolved fluorescence spectroscopic measurements with an optical fiber probe

    NASA Astrophysics Data System (ADS)

    Li, Enbang; Qiu, Hialin

    2008-12-01

    By monitoring of the emitted signal from a sample while varying the excitation wavelength, emission wavelength or both of them, fluorescence spectroscopy has become a powerful diagnostic technology. Fluorescence spectrometers can be used to measure and record the fluorescence spectra of a given sample, and have been successfully applied in different areas including biology, biochemistry, chemistry, medicine, environmental science, material science, food industry, and pharmaceutical industry. In order to increase the flexibility and applicability of conventional fluorescence spectrometers, we design an optic fiber probe for conducting the UV/Vis excitation light to a sample under study, and for collecting the fluorescence produced by the sample. Different excitation/emission fiber bundle arrangements have been fabricated and their performances have been evaluated and compared. Fiber adaptors which can be used for different commercial fluorescence spectrometers are also developed. In order to achieve space-resolved fluorescence spectroscopic measurements, we connect the fiber probe to a microscope which is mounted on a 3D traverse stage. Experiments and measurement results using the space-resolved fiber optic fluorescence spectrometer are presented in this paper.

  10. Mir Contamination Observations and Implications to the International Space Station

    NASA Technical Reports Server (NTRS)

    Soares, Carlos; Mikatarian, Ron

    2000-01-01

    A series of external contamination measurements were made on the Russian Mir Space Station. The Mir external contamination observations summarized in this paper were essential in assessing the system level impact of Russian Segment induced contamination on the International Space Station (ISS). Mir contamination observations include results from a series of flight experiments: CNES Comes-Aragatz, retrieved NASA camera bracket, Euro-Mir '95 ICA, retrieved NASA Trek blanket, Russian Astra-II, Mir Solar Array Return Experiment (SARE), etc. Results from these experiments were studied in detail to characterize Mir induced contamination. In conjunction with Mir contamination observations, Russian materials samples were tested for condensable outgassing rates in the U.S. These test results were essential in the characterization of Mir contamination sources. Once Mir contamination sources were identified and characterized, activities to assess the implications to ISS were implemented. As a result, modifications in Russian materials selection and/or usage were implemented to control contamination and mitigate risk to ISS.

  11. REFLECTIONS ON SPACE: ITS IMPLICATIONS FOR DOMESTIC AND INTERNATIONAL AFFAIRS,

    DTIC Science & Technology

    Contents: The challenge of space exploration Space and its impact on the United States The United States space effort: The cost and wisdom of the space race The space effort of the U.S.S.R. The military application of space International law and cooperation in outer space (Author)

  12. Getting together in deep space - The Rosetta space probe's long trek to Comet 67/P Churyumov-Gerasimenko

    NASA Astrophysics Data System (ADS)

    2004-02-01

    The countdown to Rosetta’s rendezvous in space began on 1 March 1997. At the end of February 2004, seven years and not a few headaches later, the European Space Agency (ESA) probe will at last be setting off on its journey to meet Comet Churyumov-Gerasimenko. The long-planned get-together will not however take place until the middle of 2014. A few months after arriving at the comet, Rosetta will release a small lander onto its surface. Then, for almost two years it will investigate Churyumov-Gerasimenko from close up. Dr Gerhard Schwehm, lead scientist for the Rosetta project, explains that, “With this mission we will be breaking new ground - this will be the first protracted cometary encounter.” The trip to the meeting place in space will certainly be a long one, located as it is some 4.5 astronomical units from the Sun, which translates into something like 675 million kilometres. Rosetta will be on the road for ten years, during which time it will clock up in excess of five billion kilometres. Launch in February 2004 Rosetta will be waved off on 26 February when it lifts off from the space centre in Kourou, French Guiana, aboard an Ariane 5 launcher. Shortly after the spacecraft’s release, its solar panels will be deployed and turned towards the Sun to build up the necessary power reserves. Its various systems and experiments will be gradually brought into operation and tested. Just three months into the mission the first active phase will be over, followed by final testing of the experiments in October 2004. Rosetta will then spend the following years flying a lonely path to the comet, passing by the Earth, Mars, the Earth and the Earth again. There is no alternative to this detour, for even Ariane 5, the most powerful launcher on the market today, lacks the power to hurl the probe on a direct route to the comet. To get the required momentum, it will rely on swing-by manœuvres, using the gravitation pull of Mars (in 2007) and the Earth (three times, in

  13. Second derivative Langmuir probe measurements in Faraday dark space in Argon d.c. gas discharge at intermediate pressures

    NASA Astrophysics Data System (ADS)

    Dimitrova, M.; Popov, Tsv K.; Todorovand, J.; Naydenova, Tsv G.

    2006-07-01

    In a d.c. discharge tube with sectional cathodes and a common grid anode, second derivative Langmuir probe measurements were performed in the Faraday dark space in argon gas discharge at intermediate pressures. Experimental results for different radial probe positions and different distances from the cathode in axial direction are presented. It is shown that the electron energy distribution function is bi-Maxwellian. Taking into account the electron depletion caused by their sinking on the probe surface, an extension of the Druyvesteyn formula is applied for more accurate determination of the electron temperature value, T, the electron density, n, and the plasma potential, Upl, from the experimental results acquired.

  14. Wall current probe: A non-invasive in situ plasma diagnostic for space and time resolved current density distribution measurement

    SciTech Connect

    Baude, R.; Gaboriau, F.; Hagelaar, G. J. M.

    2013-08-15

    In the context of low temperature plasma research, we propose a wall current probe to determine the local charged particle fluxes flowing to the chamber walls. This non-intrusive planar probe consists of an array of electrode elements which can be individually biased and for which the current can be measured separately. We detail the probe properties and present the ability of the diagnostic to be used as a space and time resolved measurement of the ion and electron current density at the chamber walls. This diagnostic will be relevant to study the electron transport in magnetized low-pressure plasmas.

  15. Wall current probe: a non-invasive in situ plasma diagnostic for space and time resolved current density distribution measurement.

    PubMed

    Baude, R; Gaboriau, F; Hagelaar, G J M

    2013-08-01

    In the context of low temperature plasma research, we propose a wall current probe to determine the local charged particle fluxes flowing to the chamber walls. This non-intrusive planar probe consists of an array of electrode elements which can be individually biased and for which the current can be measured separately. We detail the probe properties and present the ability of the diagnostic to be used as a space and time resolved measurement of the ion and electron current density at the chamber walls. This diagnostic will be relevant to study the electron transport in magnetized low-pressure plasmas.

  16. Probing theories of gravity with phase space-inferred potentials of galaxy clusters

    NASA Astrophysics Data System (ADS)

    Stark, Alejo; Miller, Christopher J.; Kern, Nicholas; Gifford, Daniel; Zhao, Gong-Bo; Li, Baojiu; Koyama, Kazuya; Nichol, Robert C.

    2016-04-01

    Modified theories of gravity provide us with a unique opportunity to generate innovative tests of gravity. In Chameleon f (R ) gravity, the gravitational potential differs from the weak-field limit of general relativity (GR) in a mass dependent way. We develop a probe of gravity which compares high mass clusters, where Chameleon effects are weak, to low mass clusters, where the effects can be strong. We utilize the escape velocity edges in the radius/velocity phase space to infer the gravitational potential profiles on scales of 0.3-1 virial radii. We show that the escape edges of low mass clusters are enhanced compared to GR, where the magnitude of the difference depends on the background field value |fR 0 ¯ | . We validate our probe using N-body simulations and simulated light cone galaxy data. For a Dark Energy Spectroscopic Instrument Bright Galaxy Sample, including observational systematics, projection effects, and cosmic variance, our test can differentiate between GR and Chameleon f (R ) gravity models, |fR 0 ¯ |=4 ×10-6 (2 ×10-6) at >5 σ (>2 σ ), more than an order of magnitude better than current cluster-scale constraints.

  17. Gradual Diffusion and Punctuated Phase Space Density Enhancements of Highly Relativistic Electrons: Van Allen Probes Observations

    NASA Technical Reports Server (NTRS)

    Baker, D. N.; Jaynes, A. N.; Li, X.; Henderson, M. G.; Kanekal, S. G.; Reeves, G. D.; Spence, H. E.; Claudepierre, S. G.; Fennell, J. F.; Hudson, M. K.

    2014-01-01

    The dual-spacecraft Van Allen Probes mission has provided a new window into mega electron volt (MeV) particle dynamics in the Earth's radiation belts. Observations (up to E (is) approximately 10MeV) show clearly the behavior of the outer electron radiation belt at different timescales: months-long periods of gradual inward radial diffusive transport and weak loss being punctuated by dramatic flux changes driven by strong solar wind transient events. We present analysis of multi-MeV electron flux and phase space density (PSD) changes during March 2013 in the context of the first year of Van Allen Probes operation. This March period demonstrates the classic signatures both of inward radial diffusive energization and abrupt localized acceleration deep within the outer Van Allen zone (L (is) approximately 4.0 +/- 0.5). This reveals graphically that both 'competing' mechanisms of multi-MeV electron energization are at play in the radiation belts, often acting almost concurrently or at least in rapid succession.

  18. Resonant detectors of gravitational wave as a possible probe of the noncommutative structure of space

    NASA Astrophysics Data System (ADS)

    Saha, Anirban; Gangopadhyay, Sunandan

    2016-10-01

    We report the plausibility of using quantum mechanical transitions, induced by the combined effect of gravitational waves (GWs) and noncommutative (NC) structure of space, among the states of a 2-dimensional harmonic oscillator, to probe the spatial NC geometry. The phonon modes excited by the passing GW within the resonant bar-detector or spherical detectors are formally identical to forced harmonic oscillator and they represent a length variation of roughly the same order of magnitude as the characteristic length-scale of spatial noncommutativity estimated from the phenomenological upper bound of the NC parameter. This motivates our present work. We employ various GW wave-forms that are typically expected from possible astronomical sources. We find that the transition probablities are quite sensitive to the nature of polarization of the GW. We also elaborate on the particular type of sources of GW, radiation from which one can induce such transitions. We speculate that this can be used as an effective probe of the spatial noncommutative structure when the quantum limit of sensitivity is achieved/surpassed in resonant bar/spherical detectors of GWs in the near future.

  19. Gravity Probe B: final results of a space experiment to test general relativity.

    PubMed

    Everitt, C W F; DeBra, D B; Parkinson, B W; Turneaure, J P; Conklin, J W; Heifetz, M I; Keiser, G M; Silbergleit, A S; Holmes, T; Kolodziejczak, J; Al-Meshari, M; Mester, J C; Muhlfelder, B; Solomonik, V G; Stahl, K; Worden, P W; Bencze, W; Buchman, S; Clarke, B; Al-Jadaan, A; Al-Jibreen, H; Li, J; Lipa, J A; Lockhart, J M; Al-Suwaidan, B; Taber, M; Wang, S

    2011-06-03

    Gravity Probe B, launched 20 April 2004, is a space experiment testing two fundamental predictions of Einstein's theory of general relativity (GR), the geodetic and frame-dragging effects, by means of cryogenic gyroscopes in Earth orbit. Data collection started 28 August 2004 and ended 14 August 2005. Analysis of the data from all four gyroscopes results in a geodetic drift rate of -6601.8±18.3  mas/yr and a frame-dragging drift rate of -37.2±7.2  mas/yr, to be compared with the GR predictions of -6606.1  mas/yr and -39.2  mas/yr, respectively ("mas" is milliarcsecond; 1  mas=4.848×10(-9)  rad).

  20. Very High Specific Energy, Medium Power Li/CFx Primary Battery for Launchers and Space Probes

    NASA Astrophysics Data System (ADS)

    Brochard, Paul; Godillot, Gerome; Peres, Jean Paul; Corbin, Julien; Espinosa, Amaya

    2014-08-01

    Benchmark with existing technologies shows the advantages of the lithium-fluorinated carbon (Li/CFx) technology for use aboard future launchers in terms of a low Total Cost of Ownership (TCO), especially for high energy demanding missions such as re-ignitable upper stages for long GTO+ missions and probes for deep space exploration.This paper presents the new results obtained on this chemistry in terms of electrical and climatic performances, abuse tests and life tests. Studies - co-financed between CNES and Saft - looked at a pure CFx version with a specific energy up to 500 Wh/kg along with a medium power of 80 to 100 W/kg.

  1. Light as a probe of the structure of space-time

    NASA Astrophysics Data System (ADS)

    Tartaglia, Angelo

    2016-05-01

    Light is an intrinsically relativistic probe and when used in an adequately sized array of ring lasers it is sensible to the curvature and to the chirality of space-time. On this basis the GINGER experiment is being implemented at the underground National Laboratories at Gran Sasso. The experiment, whose objective is the measurement of the terrestrial frame dragging effect or deviations from it, will be presented and discussed in its foundation. Furthermore, at a bigger scale, the possibilities given by the under way GAIA mission and the proposed AGP, will be analyzed with a special attention paied to the possibility of extracting information concerning the angular momenta of the sun and the main bodies of the solar system.

  2. Real-space measurement of potential distribution in PECVD ONO electrets by Kelvin probe force microscopy.

    PubMed

    Emmerich, F; Thielemann, C

    2016-05-20

    Multilayers of silicon oxide/silicon nitride/silicon oxide (ONO) are known for their good electret properties due to deep energy traps near the material interfaces, facilitating charge storage. However, measurement of the space charge distribution in such multilayers is a challenge for conventional methods if layer thickness dimensions shrink below 1 μm. In this paper, we propose an atomic force microscope based method to determine charge distributions in ONO layers with spatial resolution below 100 nm. By applying Kelvin probe force microscopy (KPFM) on freshly cleaved, corona-charged multilayers, the surface potential is measured directly along the z-axis and across the interfaces. This new method gives insights into charge distribution and charge movement in inorganic electrets with a high spatial resolution.

  3. Scalar field probes of power-law space-time singularities

    NASA Astrophysics Data System (ADS)

    Blau, Matthias; Frank, Denis; Weiss, Sebastian

    2006-08-01

    We analyse the effective potential of the scalar wave equation near generic space-time singularities of power-law type (Szekeres-Iyer metrics) and show that the effective potential exhibits a universal and scale invariant leading inverse square behaviour ~ x-2 in the ``tortoise coordinate'' x provided that the metrics satisfy the strict Dominant Energy Condition (DEC). This result parallels that obtained in [1] for probes consisting of families of massless particles (null geodesic deviation, a.k.a. the Penrose Limit). The detailed properties of the scalar wave operator depend sensitively on the numerical coefficient of the x-2-term, and as one application we show that timelike singularities satisfying the DEC are quantum mechanically singular in the sense of the Horowitz-Marolf (essential self-adjointness) criterion. We also comment on some related issues like the near-singularity behaviour of the scalar fields permitted by the Friedrichs extension.

  4. Probing the Nodal Structure of Landau Level Wave Functions in Real Space.

    PubMed

    Bindel, J R; Ulrich, J; Liebmann, M; Morgenstern, M

    2017-01-06

    The inversion layer of p-InSb(110) obtained by Cs adsorption of 1.8% of a monolayer is used to probe the Landau level wave functions within smooth potential valleys by scanning tunneling spectroscopy at 14 T. The nodal structure becomes apparent as a double peak structure of each spin polarized first Landau level, while the zeroth Landau level exhibits a single peak per spin level only. The real space data show single rings of the valley-confined drift states for the zeroth Landau level and double rings for the first Landau level. The result is reproduced by a recursive Green function algorithm using the potential landscape obtained experimentally. We show that the result is generic by comparing the local density of states from the Green function algorithm with results from a well-controlled analytic model based on the guiding center approach.

  5. Probing the Nodal Structure of Landau Level Wave Functions in Real Space

    NASA Astrophysics Data System (ADS)

    Bindel, J. R.; Ulrich, J.; Liebmann, M.; Morgenstern, M.

    2017-01-01

    The inversion layer of p -InSb (110 ) obtained by Cs adsorption of 1.8% of a monolayer is used to probe the Landau level wave functions within smooth potential valleys by scanning tunneling spectroscopy at 14 T. The nodal structure becomes apparent as a double peak structure of each spin polarized first Landau level, while the zeroth Landau level exhibits a single peak per spin level only. The real space data show single rings of the valley-confined drift states for the zeroth Landau level and double rings for the first Landau level. The result is reproduced by a recursive Green function algorithm using the potential landscape obtained experimentally. We show that the result is generic by comparing the local density of states from the Green function algorithm with results from a well-controlled analytic model based on the guiding center approach.

  6. Diagnostic of plasma streams from ion thrusters for space propulsion using emissive probes

    NASA Astrophysics Data System (ADS)

    Conde, L.; Tierno, S. P.; Domenech-Garret, J. L.; Donoso, J. M.; Castillo, M. A.; Eíriz, I.; Sáez de Ocáriz, I.

    2016-10-01

    The emissive probes are employed for the determination of the local plasma potential of plasma streams produced by ion thrusters. Its operation basically relies on electron collection and emission and are less sensitive to the ion motion than collecting probes. The diagnostic using emissive probes is reviewed with emphasis in low density plasmas. Our results support the conclusion that potential structures around the probe, as virtual cathodes, would be responsible for the operation of emissive probes in low density plasmas.

  7. Exploring Local Electrostatic Effects with Scanning Probe Microscopy: Implications for Piezoresponse Force Microscopy and Triboelectricity

    DOE PAGES

    Balke, Nina; Maksymovych, Petro; Jesse, Stephen; ...

    2014-09-25

    The implementation of contact mode Kelvin probe force microscopy (KPFM) utilizes the electrostatic interactions between tip and sample when the tip and sample are in contact with each other. Surprisingly, the electrostatic forces in contact are large enough to be measured even with tips as stiff as 4.5 N/m. As for traditional non-contact KPFM, the signal depends strongly on electrical properties of the sample, such as the dielectric constant, and the tip-properties, such as the stiffness. Since the tip is in contact with the sample, bias-induced changes in the junction potential between tip and sample can be measured with highermore » lateral and temporal resolution compared to traditional non-contact KPFM. Significant and reproducible variations of tip-surface capacitance are observed and attributed to surface electrochemical phenomena. Lastly, observations of significant surface charge states at zero bias and strong hysteretic electromechanical responses at non-ferroelectric surface have significant implications for fields such as triboelectricity and piezoresponse force microscopy.« less

  8. Exploring Local Electrostatic Effects with Scanning Probe Microscopy: Implications for Piezoresponse Force Microscopy and Triboelectricity

    SciTech Connect

    Balke, Nina; Maksymovych, Petro; Jesse, Stephen; Kravchenko, Ivan I.; Li, Qian; Kalinin, Sergei V.

    2014-09-25

    The implementation of contact mode Kelvin probe force microscopy (KPFM) utilizes the electrostatic interactions between tip and sample when the tip and sample are in contact with each other. Surprisingly, the electrostatic forces in contact are large enough to be measured even with tips as stiff as 4.5 N/m. As for traditional non-contact KPFM, the signal depends strongly on electrical properties of the sample, such as the dielectric constant, and the tip-properties, such as the stiffness. Since the tip is in contact with the sample, bias-induced changes in the junction potential between tip and sample can be measured with higher lateral and temporal resolution compared to traditional non-contact KPFM. Significant and reproducible variations of tip-surface capacitance are observed and attributed to surface electrochemical phenomena. Lastly, observations of significant surface charge states at zero bias and strong hysteretic electromechanical responses at non-ferroelectric surface have significant implications for fields such as triboelectricity and piezoresponse force microscopy.

  9. Probing the bioactivity-relevant chemical space of robust reactions and common molecular building blocks.

    PubMed

    Hartenfeller, Markus; Eberle, Martin; Meier, Peter; Nieto-Oberhuber, Cristina; Altmann, Karl-Heinz; Schneider, Gisbert; Jacoby, Edgar; Renner, Steffen

    2012-05-25

    In the search for new bioactive compounds, there is a trend toward increasingly complex compound libraries aiming to target the demanding targets of the future. In contrast, medicinal chemistry and traditional library design rely mainly on a small set of highly established and robust reactions. Here, we probe a set of 58 such reactions for their ability to sample the chemical space of known bioactive molecules, and the potential to create new scaffolds. Combined with ~26,000 common available building blocks, the reactions retrieve around 9% of a scaffold-diverse set of compounds active on human target proteins covering all major pharmaceutical target classes. Almost 80% of generated scaffolds from virtual one-step synthesis products are not present in a large set of known bioactive molecules for human targets, indicating potential for new discoveries. The results suggest that established synthesis resources are well suited to cover the known bioactivity-relevant chemical space and that there are plenty of unexplored regions accessible by these reactions, possibly providing valuable "low-hanging fruit" for hit discovery.

  10. Application of high stability oscillators to radio science experiments using deep space probes

    NASA Technical Reports Server (NTRS)

    Kursinski, Emil R.

    1990-01-01

    The microwave telecommunication links between the earth and deep space probes have long been used to conduct radio science experiments which take advantage of the phase coherency and stability of these links. These experiments measure changes in the phase delay of the signals to infer electrical, magnetic and gravitational properties of the solar system environment and beyond through which the spacecraft and radio signals pass. The precision oscillators, from which the phase of the microwave signals are derived, play a key role in the stability of these links and therefore the sensitivity of these measurements. These experiments have become a driving force behind recent and future improvements in the Deep Space Network and spacecraft oscillators and frequency and time distribution systems. Three such experiments which are key to these improvements are briefly discussed and relationship between their sensitivity and the signal phase stability is described. The first is the remote sensing of planetary atmospheres by occultation in which the radio signal passes through the atmosphere and is refracted causing the signal pathlength to change from which the pressure and the temperature of the atmosphere can be derived. The second experiment is determination of the opacity of planetary rings by passage of the radio signals through the rings. The third experiment is the research for very low frequency gravitational radiation. The fractional frequency variation of the signal is comparable to the spatial strain amplitude the system is capable of detecting. A summary of past results and future possibilities for these experiments are presented.

  11. The implications of force reflection for teleoperation in space

    SciTech Connect

    Draper, J.V.; Herndon, J.N.; Moore, W.E.

    1987-01-01

    This paper reviews previous research on teleoperator force feedback and reports results of a testing program which assessed the impact of force reflection on teleoperator task performance. Force reflection is a type of force feedback in which the forces acting on the remote portion of the teleoperator are displayed to the operator by back-driving the master controller. The testing program compared three force reflection levels: 4 to 1 (four units of force on the slave produce one unit of force at the master controller), 1 to 1, and infinity to 1 (no force reflection). Time required to complete tasks, rate of occurrence of errors, the maximum force applied to tasks components, and variability in forces applied to components during completion of representative remote handling tasks were used as dependent variables. Operators exhibited lower error rates, lower peak forces, and more consistent application of forces using force reflection than they did without it. These data support the hypothesis that force reflection provides useful information for teleoperator users. The earlier literature and the results of the experiment are discussed in terms of their implications for space-based teleoperator systems. The discussion describes the impact of force reflection on task completion performance and task strategies, as suggested by the literature. It is important to understand the trade-offs involved in using telerobotic systems with and without force reflection. Force-reflecting systems are typically more expensive (in mass, volume, and price per unit), but they reduce mean time to repair and may be safer to use, compared to systems without force reflection.

  12. Probing gravity in interplanetary space: combined use of ISA accelerometer and next-generation tracking

    NASA Astrophysics Data System (ADS)

    Peron, Roberto; Peron, R.; Bellettini, G.; Berardi, S.; Boni, A.; Cantone, C.; Coradini, A.; Currie, D. G.; Dell'Agnello, S.; Delle Monache, G. O.; Fiorenza, E.; Garattini, M.; Iafolla, V.; Intaglietta, N.; Lefevre, C.; Lops, C.; March, R.; Martini, M.; Nozzoli, S.; Patrizi, G.; Porcelli, L.; Reale, A.; Santoli, F.; Tauraso, R.; Vittori, R.

    The Solar System is a complex laboratory for testing gravitational physics. Indeed, its scale and hierarchical structure make possible a wide range of tests for gravitational theories, studying the motion of both natural and artificial objects and comparing the predictions of different theories with experimental data. Future exploration scenarios show the possibility of placing deep-space probes near the Sun or in outer Solar System, thereby extending the range of conditions in which to test directly the theories. In particular, the Sun-Earth-Moon is the most accurately known gravitational three-body laboratory, which is undergoing a new, strong wave of research and robotic exploration. In addition, the benefits of a synergetic study of planetary science and gravitational physics are of the greatest importance (as shown by the success of the Apollo program), especially in the Earth-Moon (for example with the proposed International Lunar Network, ILN), Mars-Phobos, Jovian and Saturnian sub-systems. The availability of high-quality tracking data, to be fitted by suitable dynamic models for the spacecraft dynamics, opens critical issues regarding the quality of these models, i.e. their capability of fitting data without an excessive number of empirical hypotheses. A typical case is represented by the non-gravitational phenomena, often relevant, which in general are difficult to model. More generally, gravitation tests with Lunar Laser Ranging, inner or outer Solar System probes and the appearance of the so-called "anomalies"(like the one indicated by the Pioneers), whatever their real origin (either instrumental effects or due to new physics), show the necessity of a coordinated improvement of tracking and modelization techniques. A number of steps in this directions will be discussed, employing the use of high-sensitivity accelerometers like ISA (Italian Spring Accelerometer) — in order to measure directly non-gravitational effects — and combined microwave and

  13. Magnetically insulated baffled probe for real-time monitoring of equilibrium and fluctuating values of space potentials, electron and ion temperatures, and densities

    SciTech Connect

    Demidov, V. I.; Koepke, M. E.; Raitses, Y.

    2010-10-15

    By restricting the electron-collection area of a cold Langmuir probe compared to the ion-collection area, the probe floating potential can become equal to the space potential, and thus conveniently monitored, rather than to a value shifted from the space potential by an electron-temperature-dependent offset, i.e., the case with an equal-collection-area probe. This design goal is achieved by combining an ambient magnetic field in the plasma with baffles, or shields, on the probe, resulting in species-selective magnetic insulation of the probe collection area. This permits the elimination of electron current to the probe by further adjustment of magnetic insulation which results in an ion-temperature-dependent offset when the probe is electrically floating. Subtracting the floating potential of two magnetically insulated baffled probes, each with a different degree of magnetic insulation, enables the electron or ion temperature to be measured in real time.

  14. Magnetically insulated baffled probe for real-time monitoring of equilibrium and fluctuating values of space potentials, electron and ion temperatures, and densities.

    PubMed

    Demidov, V I; Koepke, M E; Raitses, Y

    2010-10-01

    By restricting the electron-collection area of a cold Langmuir probe compared to the ion-collection area, the probe floating potential can become equal to the space potential, and thus conveniently monitored, rather than to a value shifted from the space potential by an electron-temperature-dependent offset, i.e., the case with an equal-collection-area probe. This design goal is achieved by combining an ambient magnetic field in the plasma with baffles, or shields, on the probe, resulting in species-selective magnetic insulation of the probe collection area. This permits the elimination of electron current to the probe by further adjustment of magnetic insulation which results in an ion-temperature-dependent offset when the probe is electrically floating. Subtracting the floating potential of two magnetically insulated baffled probes, each with a different degree of magnetic insulation, enables the electron or ion temperature to be measured in real time.

  15. A Model Space Mission to probe Einstein's Equivalence Principle - The STE-QUEST Study

    NASA Astrophysics Data System (ADS)

    Heske, Astrid; Cacciapuoti, Luigi; Gehler, Martin

    Understanding General Relativity at all scales requires, in particular, understanding gravity at quantum level. To attempt this, tests of the most prominent aspect of General Relativity, the Einstein Equivalence Principle, can be performed with the next generation of atomic quantum sensors to significantly improved accuracy. To exploit the ultimate limits of atomic sensors a dedicated space platform is needed; the advantages space offers are, among others, unperturbed free-fall conditions, longer interaction times per measurement and large variations in velocity and gravitational field. In the frame of the third medium class launch opportunity of ESA's Cosmic Vision 2015 - 2025 programme a study was conducted - STE-QUEST (Space-Time Explorer and QUantum Equivalence principle Test), one of the candidates for a medium class mission - and the feasibility of such a mission assessed. The spacecraft would carry two instruments probing the different aspects of the Einstein Equivalence Principle: begin{enumerate} A dual species ( (87) Rb and (85) Rb) atom interferometer to probe the universality of propagation of matter waves. A high-performance time and frequency link dedicated to comparison of atomic clocks on ground. The specific primary science objectives for STE-QUEST are: begin{enumerate} Universality of propagation of matter waves test begin{itemize} Test of the universality of free fall of matter waves to an uncertainty of the Eötvös ratio lower than 2*10 (-15) . Gravitational redshift tests begin{itemize} Sun gravitational red-shift measurement to a fractional uncertainty of 2*10 (-6) , with an ultimate goal of 5*10 (-7) . Moon gravitational red-shift measurement to a fractional uncertainty of 4*10 (-4) , with an ultimate goal of 9*10 (-5) . Such a measurement has never been attempted before. The availability of an atomic clock on-board the spacecraft (optional) would additionally allow testing the Earth gravitational red-shift measurement to a fractional

  16. Probing cosmology and gravity with redshift-space distortions around voids

    SciTech Connect

    Hamaus, Nico; Sutter, P.M.; Lavaux, Guilhem; Wandelt, Benjamin D. E-mail: sutter@iap.fr E-mail: wandelt@iap.fr

    2015-11-01

    Cosmic voids in the large-scale structure of the Universe affect the peculiar motions of objects in their vicinity. Although these motions are difficult to observe directly, the clustering pattern of their surrounding tracers in redshift space is influenced in a unique way. This allows to investigate the interplay between densities and velocities around voids, which is solely dictated by the laws of gravity. With the help of N-body simulations and derived mock-galaxy catalogs we calculate the average density fluctuations around voids identified with a watershed algorithm in redshift space and compare the results with the expectation from general relativity and the ΛCDM model. We find linear theory to work remarkably well in describing the dynamics of voids. Adopting a Bayesian inference framework, we explore the full posterior of our model parameters and forecast the achievable accuracy on measurements of the growth rate of structure and the geometric distortion through the Alcock-Paczyński effect. Systematic errors in the latter are reduced from ∼15% to ∼5% when peculiar velocities are taken into account. The relative parameter uncertainties in galaxy surveys with number densities comparable to the SDSS MAIN (CMASS) sample probing a volume of 1h{sup −3}Gpc{sup 3} yield σ{sub f/b}/(f/b).∼2% (20%) and σ{sub D{sub A{sub H}}}/D{sub AH∼0}.2% (2%), respectively. At this level of precision the linear-theory model becomes systematics dominated, with parameter biases that fall beyond these values. Nevertheless, the presented method is highly model independent; its viability lies in the underlying assumption of statistical isotropy of the Universe.

  17. Probing free-space quantum channels with laboratory-based experiments

    NASA Astrophysics Data System (ADS)

    Bohmann, M.; Kruse, R.; Sperling, J.; Silberhorn, C.; Vogel, W.

    2017-06-01

    Atmospheric channels are a promising candidate to establish secure quantum communication on a global scale. However, due to their turbulent nature, it is crucial to understand the impact of the atmosphere on the quantum properties of light and examine it experimentally. In this paper, we introduce a method to probe atmospheric free-space links with quantum light on a laboratory scale. In contrast to previous works, our method models arbitrary intensity losses caused by turbulence to emulate general atmospheric conditions. This allows us to characterize turbulent quantum channels in a well-controlled manner. To implement this technique, we perform a series of measurements with different constant attenuations and simulate the fluctuating losses by combining the obtained data. We directly test the proposed method with an on-chip source of nonclassical light and a time-bin-multiplexed detection system. With the obtained data, we characterize the nonclassicality of the generated states for different atmospheric noise models and analyze a postselection protocol. This general technique in atmospheric quantum optics allows for studying turbulent quantum channels and predicting their properties for future applications.

  18. Recent Advances in Cantilever-Free Scanning Probe Lithography: High-Throughput, Space-Confined Synthesis of Nanostructures and Beyond.

    PubMed

    He, Qiyuan; Tan, Chaoliang; Zhang, Hua

    2017-05-23

    Scalability is the major challenge for scanning probe lithography (SPL). Recently developed cantilever-free scanning probe technologies provide a solution to the issue of scalability by incorporating massive arrays of polymer pens, which fundamentally overcome the low-throughput nature of SPL. The further development of cantilever-free SPL brings up a variety of applications in electronics, biology, and chemical synthesis. In this Perspective, we highlight the space-confined synthesis of complex nanostructures enabled by different types of cantilever-free SPL technologies.

  19. Reacting to nuclear power systems in space: American public protests over outer planetary probes since the 1980s

    NASA Astrophysics Data System (ADS)

    Launius, Roger D.

    2014-03-01

    The United States has pioneered the use of nuclear power systems for outer planetary space probes since the 1970s. These systems have enabled the Viking landings to reach the surface of Mars and both Pioneers 10 and 11 and Voyagers 1 and 2 to travel to the limits of the solar system. Although the American public has long been concerned about safety of these systems, in the 1980s a reaction to nuclear accidents - especially the Soviet Cosmos 954 spacecraft destruction and the Three Mile Island nuclear power plant accidents - heightened awareness about the hazards of nuclear power and every spacecraft launch since that time has been contested by opponents of nuclear energy. This has led to a debate over the appropriateness of the use of nuclear power systems for spacecraft. It has also refocused attention on the need for strict systems of control and rigorous checks and balances to assure safety. This essay describes the history of space radioisotope power systems, the struggles to ensure safe operations, and the political confrontation over whether or not to allow the launch the Galileo and Cassini space probes to the outer planets. Effectively, these efforts have led to the successful flights of 12 deep space planetary probes, two-thirds of them operated since the accidents of Cosmos 954, Three Mile Island, and Chernobyl.

  20. Spectrophotometric probe

    DOEpatents

    Prather, William S.; O'Rourke, Patrick E.

    1994-01-01

    A support structure bearing at least one probe for making spectrophotometric measurements of a fluid using a source of light and a spectrophotometer. The probe includes a housing with two optical fibers and a planoconvex lens. A sleeve bearing a mirror surrounds the housing. The lens is separated from the mirror by a fixed distance, defining an interior space for receiving a volume of the fluid sample. A plurality of throughholes extending through the sleeve communicate between the sample volume and the exterior of the probe, all but one hole bearing a screen. A protective jacket surrounds the probe. A hollow conduit bearing a tube is formed in the wall of the probe for venting any air in the interior space when fluid enters. The probe is held at an acute angle so the optic fibers carrying the light to and from the probe are not bent severely on emergence from the probe.

  1. Spectrophotometric probe

    DOEpatents

    Prather, W.S.; O'Rourke, P.E.

    1994-08-02

    A support structure is described bearing at least one probe for making spectrophotometric measurements of a fluid using a source of light and a spectrophotometer. The probe includes a housing with two optical fibers and a planoconvex lens. A sleeve bearing a mirror surrounds the housing. The lens is separated from the mirror by a fixed distance, defining an interior space for receiving a volume of the fluid sample. A plurality of throughholes extending through the sleeve communicate between the sample volume and the exterior of the probe, all but one hole bearing a screen. A protective jacket surrounds the probe. A hollow conduit bearing a tube is formed in the wall of the probe for venting any air in the interior space when fluid enters. The probe is held at an acute angle so the optic fibers carrying the light to and from the probe are not bent severely on emergence from the probe. 3 figs.

  2. IMPLICATIONS OF NEW MEDIA FOR SPACE AND BUILDING DESIGN.

    ERIC Educational Resources Information Center

    CHRISTIANSEN, KENNETH A.

    THE EXPANDING ROLE OF EDUCATIONAL TELEVISION AND OTHER INSTRUCTIONAL AIDS AND MEDIA IN THE LEARNING MEDIA IS DISCUSSED IN TERMS OF APPROPRIATE SPACE DESIGN AND SPACE UTILIZATION. THREE AREAS ARE IDENTIFIED IN THE NEW MEDIA--(1) PROJECTION DEVICES, (2) NONPROJECTION DEVICES, AND (3) TELEVISION. ARCHITECTURE AND DESIGN CONCERNS ARE DEFINED AS--(1)…

  3. Group-galaxy correlations in redshift space as a probe of the growth of structure

    NASA Astrophysics Data System (ADS)

    Mohammad, F. G.; de la Torre, S.; Bianchi, D.; Guzzo, L.; Peacock, J. A.

    2016-05-01

    We investigate the use of the cross-correlation between galaxies and galaxy groups to measure redshift-space distortions (RSD) and thus probe the growth rate of cosmological structure. This is compared to the classical approach based on using galaxy auto-correlation. We make use of realistic simulated galaxy catalogues that have been constructed by populating simulated dark matter haloes with galaxies through halo occupation prescriptions. We adapt the classical RSD dispersion model to the case of the group-galaxy cross-correlation function and estimate the RSD parameter β by fitting both the full anisotropic correlation function ξs(rp, π) and its multipole moments. In addition, we define a modified version of the latter statistics by truncating the multipole moments to exclude strongly non-linear distortions at small transverse scales. We fit these three observable quantities in our set of simulated galaxy catalogues and estimate statistical and systematic errors on β for the case of galaxy-galaxy, group-group, and group-galaxy correlation functions. When ignoring off-diagonal elements of the covariance matrix in the fitting, the truncated multipole moments of the group-galaxy cross-correlation function provide the most accurate estimate, with systematic errors below 3 per cent when fitting transverse scales larger than 10 h-1 Mpc. Including the full data covariance enlarges statistical errors but keep unchanged the level of systematic error. Although statistical errors are generally larger for groups, the use of group-galaxy cross-correlation can potentially allow the reduction of systematics while using simple linear or dispersion models.

  4. Implications of Privacy Needs and Interpersonal Distancing Mechanisms for Space Station Design

    NASA Technical Reports Server (NTRS)

    Harrison, A. A.; Sommer, R.; Struthers, N.; Hoyt, K.

    1986-01-01

    The literature on privacy needs, personal space, interpersonal distancing, and crowding is reveiwed with special reference to spaceflight and spaceflight analogous conditions. A quantitative model is proposed for understanding privacy, interpersonal distancing, and performance. The implications for space station design is described.

  5. Evidence of Second-Order Factor Structure in a Diagnostic Problem Space: Implications for Medical Education.

    ERIC Educational Resources Information Center

    Papa, Frank J.; And Others

    1997-01-01

    Chest pain was identified as a specific medical problem space, and disease classes were modeled to define it. Results from a test taken by 628 medical residents indicate a second-order factor structure that suggests that chest pain is a multidimensional problem space. Implications for medical education are discussed. (SLD)

  6. Atrial Arrhythmias and Their Implications for Space Flight - Introduction

    NASA Technical Reports Server (NTRS)

    Polk, J. D.; Barr, Y. R.; Bauer, P.; Hamilton, D. R.; Kerstman, E.; Tarver, B.

    2010-01-01

    This panel will discuss the implications of atrial arrhythmias in astronauts from a variety of perspectives; including historical data, current practices, and future challenges for exploration class missions. The panelists will present case histories, outline the evolution of current NASA medical standards for atrial arrhythmias, discuss the use of predictive tools, and consider potential challenges for current and future missions.

  7. Space Weathering of Itokawa Particles: Implications for Regolith Evolution

    NASA Technical Reports Server (NTRS)

    Berger, Eve L.; Keller, Lindsay P.

    2015-01-01

    Space weathering processes such as solar wind irradiation and micrometeorite impacts are known to alter the the properties of regolith materials exposed on airless bodies. The rates of space weathering processes however, are poorly constrained for asteroid regoliths, with recent estimates ranging over many orders of magnitude. The return of surface samples by JAXA's Hayabusa mission to asteroid 25143 Itokawa, and their laboratory analysis provides "ground truth" to anchor the timescales for space weathering processes on airless bodies. Here, we use the effects of solar wind irradiation and the accumulation of solar flare tracks recorded in Itokawa grains to constrain the rates of space weathering and yield information about regolith dynamics on these timescales.

  8. Space-Derived Transparency: Players, Policies, Implications, and Synergies

    NASA Astrophysics Data System (ADS)

    Kinnan, C. J.

    2001-06-01

    Space-derived transparency will become a common means of monitoring, preventing, and mitigating crises, verifying compliance with treaties and law, and enabling confidence and security building measures. Democratization and globalization, the proliferation of information technologies, the availability of commercial space high-resolution imagery, and the growing influence of NGOs invite this question: What is (space-derived) transparency and what effect does it have on US security policy? Three camps have emerged in the debate -Horaeists who seek to build a transnational society through complete transparency; Preservationists, mostly military, who fear the threat to national security, want to deny most space-derived information to non-traditional/non-state actors; and Synergists who seek to capitalize on the best of both camps. There is evidence suggesting that space-derived transparency is an inevitable trend and will resist even the best means of preservationist control. Space-derived transparency may change the dynamic of the security environment by introducing new players into the policy fomentation and implementation process. These players, if not properly schooled in imagery analysis or the potential effects of their use of misinterpreted space-derived imagery, could force policy makers to make fast, ill-considered decisions in order to respond to incidents. In some cases this fast response will defuse potential crises and in other situations these rushed decisions might result in policies without considering the potential consequences, which could turn incidents into crises. Space-derived transparency is a step forward into the future for each camp . . . the challenge for the United States lies in forging synergies in an increasingly transparent world while maintaining the balance between openness and security.

  9. Legal Implications of Nuclear Propulsion for Space Objects

    NASA Astrophysics Data System (ADS)

    Pop, V.

    2002-01-01

    This paper is intended to examine nuclear propulsion concepts such as "Project Orion", "Project Daedalus", NERVA, VASIMIR, from the legal point of view. The UN Principles Relevant to the Use of Nuclear Power Sources in Outer Space apply to nuclear power sources in outer space devoted to the generation of electric power on board space objects for non-propulsive purposes, and do not regulate the use of nuclear energy as a means of propulsion. However, nuclear propulsion by means of detonating atomic bombs (ORION) is, in principle, banned under the 1963 Treaty Banning Nuclear Weapon Tests in the Atmosphere, in Outer Space, and Under Water. The legality of use of nuclear propulsion will be analysed from different approaches - historical (i.e. the lawfulness of these projects at the time of their proposal, at the present time, and in the future - in the light of the mutability and evolution of international law), spatial (i.e. the legal regime governing peaceful nuclear explosions in different spatial zones - Earth atmosphere, Earth orbit, Solar System, and interstellar space), and technical (i.e, the legal regime applicable to different nuclear propulsion techniques, and to the various negative effects - e.g. damage to other space systems as an effect of the electromagnetic pulse, etc). The paper will analyse the positive law, and will also come with suggestions "de lege ferenda".

  10. Some Implications of Space Tourism for Extraterrestrial Resources

    NASA Astrophysics Data System (ADS)

    Rogers, T. F.

    1999-01-01

    The Purpose and Scope of the Roundtable "to bring together people with ideas about what will be useful products in the space environment with those who know how to produce materials on Earth." When considering extraterrestrial resources in the context of their use in support of general public space tourism it is important to broaden this definition of Scope in certain ways. The first stages of extraterrestrial space tourism will probably take place in the Earth's lower atmosphere - far from the Moon or the planets, and even well below Earth orbit. Sophisticated aircraft could take tourists up to altitudes approaching 20 miles for short periods. And the earliest of fully reusable space transportation vehicles should be able to reach some 50 miles in altitude for short trips. Later, Earth multi-orbit trips could be offered, to be followed by stays in residence in LEO hotels for days. In time, trips could take place to/from the Moon, eventually with stays there. It should be appreciated that there are two most important extraterrestrial resources immediately available for space tourism use. They are not "materials" or "products," but are two vital space "resource intangibles."

  11. Space and time-resolved probing of heterogeneous catalysis reactions using lab-on-a-chip

    NASA Astrophysics Data System (ADS)

    Navin, Chelliah V.; Krishna, Katla Sai; Theegala, Chandra S.; Kumar, Challa S. S. R.

    2016-03-01

    Probing catalytic reactions on a catalyst surface in real time is a major challenge. Herein, we demonstrate the utility of a continuous flow millifluidic chip reactor coated with a nanostructured gold catalyst as an effective platform for in situ investigation of the kinetics of catalytic reactions by taking 5-(hydroxymethyl)furfural (HMF) to 2,5-furandicarboxylic acid (FDCA) conversion as a model reaction. The idea conceptualized in this paper can not only dramatically change the ability to probe the time-resolved kinetics of heterogeneous catalysis reactions but also used for investigating other chemical and biological catalytic processes, thereby making this a broad platform for probing reactions as they occur within continuous flow reactors.Probing catalytic reactions on a catalyst surface in real time is a major challenge. Herein, we demonstrate the utility of a continuous flow millifluidic chip reactor coated with a nanostructured gold catalyst as an effective platform for in situ investigation of the kinetics of catalytic reactions by taking 5-(hydroxymethyl)furfural (HMF) to 2,5-furandicarboxylic acid (FDCA) conversion as a model reaction. The idea conceptualized in this paper can not only dramatically change the ability to probe the time-resolved kinetics of heterogeneous catalysis reactions but also used for investigating other chemical and biological catalytic processes, thereby making this a broad platform for probing reactions as they occur within continuous flow reactors. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr06752a

  12. Implications of Public Opinion for Space Program Planning, 1980 - 2000

    NASA Technical Reports Server (NTRS)

    Overholt, W.; Wiener, A. J.; Yokelson, D.

    1975-01-01

    The effect of public opinion on future space programs is discussed in terms of direct support, apathy, or opposition, and concern about the tax burden, budgetary pressures, and national priorities. Factors considered include: the salience and visibility of NASA as compared with other issues, the sources of general pressure on the federal budget which could affect NASA, the public's opinions regarding the size and priority of NASA'S budget, the degree to which the executive can exercise leverage over NASA's budget through influencing or disregarding public opinion, the effects of linkages to other issues on space programs, and the public's general attitudes toward the progress of science.

  13. China in Space: Implications for U.S. Military Strategy

    DTIC Science & Technology

    2007-01-01

    a student at the  Industrial  College  of the Armed Forces. It won the Strategic Article  category of the 2007 Chairman of the Joint Chiefs of  Staff...tech industrial base much as the Apollo program did in the United States.5 In addition to economic development, China’s space program will likely...ndu.edu/ login?url=http://proquest.umi.com/pqdweb?did= 1144517361&Fmt=3&clientId=3921&RQT=309&V Name=PQD>. 4 Michael Westlake, “Space program engen

  14. Implications of Gun Launch to Space for Nanosatellite Architectures

    NASA Technical Reports Server (NTRS)

    Palmer, Miles R.

    1995-01-01

    Engineering and economic scaling factors for gun launch to space (GLTS) systems are compared to conventional rocket launch systems. It is argued that GLTS might reduce the cost of small satellite development and launch in the mid to far term, thereby inducing a shift away from large centralized geosynchronous communications satellites to small proliferated low earth orbit systems.

  15. China’s Space Capabilities and Their Regional Security Implications

    DTIC Science & Technology

    2011-03-18

    Cooperation Organization clearly shows its intention in building its international political capital. Therefore, in addition to its economic magnetic ...in 2003, the U.S. military effectively used space capabilities to support its war efforts in almost every aspect.40 Its lightening maneuver pace and

  16. Spacecraft charging and plasma interaction implications for large space systems

    NASA Technical Reports Server (NTRS)

    Miller, E.; Stauber, M.; Rossi, M.; Fischbein, W.

    1978-01-01

    Specific discharge mechanisms, plasma interactions, and scale effects associated with very large spacecraft are studied. The large area, low density character, and extensive use of non-conducting materials is thought to have a major impact on the performance and survivability of many large space systems.

  17. Modulation of the Foreign Body Reaction for Implants in the Subcutaneous Space: Microdialysis Probes as Localized Drug Delivery/Sampling Devices

    PubMed Central

    Mou, Xiaodun; Lennartz, Michelle R; Loegering, Daniel J; Stenken, Julie A

    2011-01-01

    Modulation of the foreign body reaction is considered to be an important step toward creation of implanted sensors with reliable long-term performance. In this work, microdialysis probes were implanted into the subcutaneous space of Sprague-Dawley rats. The probe performance was evaluated by comparing collected endogenous glucose concentrations with internal standard calibration (2-deoxyglucose, antipyrine, and vitamin B12). Probes were tested until failure, which for this work was defined as loss of fluid flow. In order to determine the effect of fibrous capsule formation on probe function, monocyte chemoattractant protein-1/CC chemokine ligand 2 (MCP-1/CCL2) was delivered locally via the probe to increase capsule thickness and dexamethasone 21-phosphate was delivered to reduce capsule thickness. Probes delivering MCP-1 had a capsule that was twice the thickness (500–600 μm) of control probes (200–225 μm) and typically failed 2 days earlier than control probes. Probes delivering dexamethasone 21-phosphate had more fragile capsules and the probes typically failed 2 days later than controls. Unexpectedly, extraction efficiency and collected glucose concentrations exhibited minor differences between groups. This is an interesting result in that the foreign body capsule formation was related to the duration of probe function but did not consistently relate to probe calibration. PMID:21722577

  18. Bioavailability of xenobiotics in unsaturated soils – implications for nucleic acid based stable isotope probing

    USDA-ARS?s Scientific Manuscript database

    The use of stable isotopes to label phylogenetically informative biomolecules (phospholipid fatty acids, DNA, or RNA), typically referred to as stable isotope probing (SIP) has the potential of providing definitive evidence that a detected population is active in a specific process, if that process ...

  19. International Space Station Execution Replanning Process: Trends and Implications

    NASA Technical Reports Server (NTRS)

    McCormick, Robet J.

    2007-01-01

    International Space Station is a joint venture. Because of this, ISS execution planning- planning within the week for the ISS requires coordination across multiple partner, and the associated processes and tools to allow this coordination to occur. These processes and tools are currently defined and are extensively used. This paper summarizes these processes, and documents the current data trends associated with these processes and tools, with a focus on the metrics provided from the ISS Planning Product Change Request (PPCR) tool. As NASA's Vision for Space Exploration and general Human spaceflight trends are implemented, the probability of joint venture long duration programs such as ISS, with varying levels of intergovernmental and/or corporate partnership, will increase. Therefore, the results of this PPCR analysis serve as current Lessons learned for the ISS and for further similar ventures.

  20. Operational Implications of Sovereignty and Freedom of Navigation in Space

    DTIC Science & Technology

    2001-04-01

    during the periods of land and gold rushes .1 As with the U.S. land and gold rushes , there are military advantages to be had with space based C2, C4, ISR...we call this the "code of conduct," but either way, it means the same thing œ we want to avoid the Wild West, or gold rush mentality œ we want to

  1. Space and time-resolved probing of heterogeneous catalysis reactions using lab-on-a-chip.

    PubMed

    Navin, Chelliah V; Krishna, Katla Sai; Theegala, Chandra S; Kumar, Challa S S R

    2016-03-14

    Probing catalytic reactions on a catalyst surface in real time is a major challenge. Herein, we demonstrate the utility of a continuous flow millifluidic chip reactor coated with a nanostructured gold catalyst as an effective platform for in situ investigation of the kinetics of catalytic reactions by taking 5-(hydroxymethyl)furfural (HMF) to 2,5-furandicarboxylic acid (FDCA) conversion as a model reaction. The idea conceptualized in this paper can not only dramatically change the ability to probe the time-resolved kinetics of heterogeneous catalysis reactions but also used for investigating other chemical and biological catalytic processes, thereby making this a broad platform for probing reactions as they occur within continuous flow reactors.

  2. Sealing scientific probes against deep space and the Venusian environment A tough job

    NASA Technical Reports Server (NTRS)

    Pokras, J.; Reinert, R. P.; Switz, R. J.

    1978-01-01

    The Pioneer Venus mission evolved from studies conducted during the late 1960s and early 1970s. It was found that a need existed for low cost orbiters and landers to explore the planet. The considered mission was to be accomplished with six separate vehicles arriving at Venus nearly simultaneously in mid-December 1978. The probes are designed to survive entry and descent into the atmosphere. A description is presented of the approaches used to maintain sealing integrity for the large and small probes under the constraints imposed by the harsh Venusian environment. Attention is given to probe vehicle configuration, pressure vessel sealing requirements, material and configuration considerations, permanent seals, separable seals, development problems, and aspects of seal testing.

  3. Sealing scientific probes against deep space and the Venusian environment A tough job

    NASA Technical Reports Server (NTRS)

    Pokras, J.; Reinert, R. P.; Switz, R. J.

    1978-01-01

    The Pioneer Venus mission evolved from studies conducted during the late 1960s and early 1970s. It was found that a need existed for low cost orbiters and landers to explore the planet. The considered mission was to be accomplished with six separate vehicles arriving at Venus nearly simultaneously in mid-December 1978. The probes are designed to survive entry and descent into the atmosphere. A description is presented of the approaches used to maintain sealing integrity for the large and small probes under the constraints imposed by the harsh Venusian environment. Attention is given to probe vehicle configuration, pressure vessel sealing requirements, material and configuration considerations, permanent seals, separable seals, development problems, and aspects of seal testing.

  4. Can Row Spacing Influence Arthropod Communities in Soybean? Implications for Early and Late Planting.

    PubMed

    Buchanan, Amanda L; Zobel, Emily; Hinds, Jermaine; Rosario-Lebron, Armando; Hooks, Cerruti R R

    2015-06-01

    Row spacing in agricultural systems can influence crop yield as well as pest and predator abundances. Soybean (Glycine max L. Merrill) growers in Maryland typically plant in narrow (∼19 cm), medium (∼38 cm), or wide (∼76 cm)-spaced rows, and there is a general lack of information on how these row-spacing schemes influence arthropod abundance and soybean yields. A study was conducted during two growing seasons to determine the effect of soybean row spacing and planting date (early and late) on soybean arthropods and yield. Despite a great deal of variation in arthropod responses to row spacing, and interactions between row spacing and study year, leaf-feeding herbivores were generally more abundant in narrow-spaced soybeans. All arthropod functional groups were more abundant, and yield was greater in early-planted soybeans relative to late-planted soybeans. Potential causes and implications of these finding are discussed.

  5. On the accuracy of the relativistic parameters beta, gamma, and the solar oblateness coefficient J2, as deduced from ranging data of a drag-free space probe

    NASA Technical Reports Server (NTRS)

    Roth, E. A.

    1971-01-01

    Motion in the general gravity field is described mathematically. A covariance analysis, based on two simple models, is presented. Two drag-free space probes were considered, for which the orbital elements are given.

  6. Human factors in space station architecture 1: Space station program implications for human factors research

    NASA Technical Reports Server (NTRS)

    Cohen, M. M.

    1985-01-01

    The space station program is based on a set of premises on mission requirements and the operational capabilities of the space shuttle. These premises will influence the human behavioral factors and conditions on board the space station. These include: launch in the STS Orbiter payload bay, orbital characteristics, power supply, microgravity environment, autonomy from the ground, crew make-up and organization, distributed command control, safety, and logistics resupply. The most immediate design impacts of these premises will be upon the architectural organization and internal environment of the space station.

  7. Insurance and indemnification implications of future space projects

    NASA Technical Reports Server (NTRS)

    O'Brien, John E.

    1987-01-01

    NASA options regarding insurance and indemnification policies as they relate to NASA customers and contractors are described. The foundation for the discussion is the way in which NASA is planning to return the Space Shuttle fleet to safe flight as well as current U.S. policy concerning future uses of the Shuttle fleet. Issues discussed include: the nature of the Shuttle manifest; the policy regarding property damage or destruction; insurance against liability to third parties; the reduction of the scope of the risk to be insured; NASA as the insurer; a sharing arrangement between the user and NASA; and contractors and subcontractors involved in Shuttle operations.

  8. Insurance and indemnification implications of future space projects

    NASA Technical Reports Server (NTRS)

    O'Brien, John E.

    1987-01-01

    NASA options regarding insurance and indemnification policies as they relate to NASA customers and contractors are described. The foundation for the discussion is the way in which NASA is planning to return the Space Shuttle fleet to safe flight as well as current U.S. policy concerning future uses of the Shuttle fleet. Issues discussed include: the nature of the Shuttle manifest; the policy regarding property damage or destruction; insurance against liability to third parties; the reduction of the scope of the risk to be insured; NASA as the insurer; a sharing arrangement between the user and NASA; and contractors and subcontractors involved in Shuttle operations.

  9. 1958 NASA/USAF Space Probes (ABLE-1). Volume 3; Vehicles, Trajectories, and Flight Histories

    NASA Technical Reports Server (NTRS)

    1959-01-01

    The three NASA/USAF lunar probes of August 17, October 13, and November 8, 1958 are described. Details of the program, the vehicles, the payloads, the firings, the tracking, and the results are presented. Principal result was the first experimental verification of a confined radiation zone of the type postulated by Van Allen and others.

  10. Nano-optical scan probes: Opening doors to previously-inaccessible parameter spaces

    SciTech Connect

    Schuck, James

    2014-06-08

    I will discuss recent progress on new near-field probe geometries, including the “campanile” geometry, which has been used in recent hyperspectral imaging experiments, providing nanoscale spectral information distinct from what is obtained with other methods. Article not available.

  11. 1958 NASA/USAF Space Probes (ABLE-1). Volume 2; Payload and Experiments

    NASA Technical Reports Server (NTRS)

    1959-01-01

    The three NASA/USAF lunar probes of August 17, October 13, and November 8, 1958 are described. Details of the program, the vehicles, the payloads, the firings, the tracking, and the results are presented. Principal result was the first experimental verification of a confined radiation zone of the type postulated by Van Allen and others.

  12. Future Mission Trends and their Implications for the Deep Space Network

    NASA Technical Reports Server (NTRS)

    Abraham, Douglas S.

    2006-01-01

    This viewgraph presentation discusses the direction of future missions and it's significance to the Deep Space Network. The topics include: 1) The Deep Space Network (DSN); 2) Past Missions Driving DSN Evolution; 3) The Changing Mission Paradigm; 4) Assessing Future Mission Needs; 5) Link Support Trends; 6) Downlink Rate Trends; 7) Uplink Rate Trends; 8) End-to-End Link Difficulty Trends; 9) Summary: Future Mission Trend Drivers; and 10) Conclusion: Implications for the DSN.

  13. The Art of Military Discovery. Chinese Air and Space Power Implications for the USAF

    DTIC Science & Technology

    2010-01-01

    their studies acknowledge that any efforts to analyze China’s space programs are hampered by the lack of transparency.34 Lt Col Carol Welsch , in her...in Chinese military writings, according to Colonel Welsch , is “only a desired capability” (emphasis in original).37 Lt Col [ 44 ] Strategic Studies... Welsch , “Protecting the Heavens: Implications of China’s Antisatellite Programs,” (Research report, AU, 2008), 5—Recipient of AFSPC Best AWC Space

  14. Gravitational biology and space life sciences: current status and implications for the Indian space programme.

    PubMed

    Dayanandan, P

    2011-12-01

    This paper is an introduction to gravitational and space life sciences and a summary of key achievements in the field. Current global research is focused on understanding the effects of gravity/microgravity onmicrobes, cells, plants, animals and humans. It is now established that many plants and animals can progress through several generations in microgravity. Astrobiology is emerging as an exciting field promoting research in biospherics and fabrication of controlled environmental life support systems. India is one of the 14-nation International Space Exploration Coordination Group (2007) that hopes that someday humans may live and work on other planets within the Solar System. The vision statement of the Indian Space Research Organization (ISRO) includes planetary exploration and human spaceflight. While a leader in several fields of space science, India is yet to initiate serious research in gravitational and life sciences. Suggestions are made here for establishing a full-fledged Indian space life sciences programme.

  15. Galactic exploration by directed self-replicating probes, and its implications for the Fermi paradox

    NASA Astrophysics Data System (ADS)

    Barlow, Martin T.

    2013-01-01

    This paper proposes a long-term scheme for robotic exploration of the galaxy, and then considers the implications in terms of the `Fermi paradox' and our search for extraterrestrial intelligence (ETI). We discuss the `Galactic ecology' of civilizations in terms of the parameters T (time between ET civilizations arising) and L, the lifetime of these civilizations. Six different regions are described.

  16. Evidence of space charge regions within semiconductor nanowires from Kelvin probe force microscopy.

    PubMed

    Narváez, Angela C; Chiaramonte, Thalita; Vicaro, Klaus O; Clerici, João H; Cotta, Mônica A

    2009-11-18

    We have studied the equilibrium electrostatic profile of III-V semiconductor nanowires using Kelvin probe force microscopy. Qualitative agreement of the measured surface potential levels and expected Fermi level variation for pure InP and InAs nanowires is obtained from electrical images with spatial resolution as low as 10 nm. Surface potential mapping for pure and heterostructured nanowires suggests the existence of charge transfer mechanisms and the formation of a metal-semiconductor electrical contact at the nanowire apex.

  17. Origins of the Ambient Solar Wind: Implications for Space Weather

    NASA Astrophysics Data System (ADS)

    Cranmer, Steven R.; Gibson, Sarah E.; Riley, Pete

    2017-10-01

    The Sun's outer atmosphere is heated to temperatures of millions of degrees, and solar plasma flows out into interplanetary space at supersonic speeds. This paper reviews our current understanding of these interrelated problems: coronal heating and the acceleration of the ambient solar wind. We also discuss where the community stands in its ability to forecast how variations in the solar wind (i.e., fast and slow wind streams) impact the Earth. Although the last few decades have seen significant progress in observations and modeling, we still do not have a complete understanding of the relevant physical processes, nor do we have a quantitatively precise census of which coronal structures contribute to specific types of solar wind. Fast streams are known to be connected to the central regions of large coronal holes. Slow streams, however, appear to come from a wide range of sources, including streamers, pseudostreamers, coronal loops, active regions, and coronal hole boundaries. Complicating our understanding even more is the fact that processes such as turbulence, stream-stream interactions, and Coulomb collisions can make it difficult to unambiguously map a parcel measured at 1 AU back down to its coronal source. We also review recent progress—in theoretical modeling, observational data analysis, and forecasting techniques that sit at the interface between data and theory—that gives us hope that the above problems are indeed solvable.

  18. Space shuttle ram glow: Implication of NO2 recombination continuum

    NASA Technical Reports Server (NTRS)

    Swenson, G. R.; Mende, S. B.; Clifton, S.

    1985-01-01

    The ram glow data gathered to data from imaging experiments on space shuttle suggest the glow is a continuum (within 34 angstrom resolution); the continuum shape is such that the peak is near 7000 angstroms decreasing to the blue and red, and the average molecular travel leading to emission after leaving the surface is 20 cm (assuming isotropic scattering from the surface). Emission continuum is rare in molecular systems but the measured spectrum does resemble the laboratory spectrum of NO2 (B) recombination continuum. The thickness of the observed emission is consistent with the NO2 hypothesis given an exit velocity of approx. 2.5 km/sec (1.3 eV) which leaves approx. 3.7 eV of ramming OI energy available for unbonding the recombined NO2 from the surface. The NO2 is formed in a 3-body recombination of OI + NO + m = NO2 + m where OI originates from the atmosphere and NO is chemically formed on the surface from atmospheric NI and OI. The spacecraft surface then acts as the n for the reaction: Evidence exists from orbital mass spectrometer data that the NO and NO2 chemistry described in this process does occur on surfaces of spectrometer orifices in orbit. Surface temperature effects are likely a factor in the NO sticking efficiency and, therefore, glow intensities.

  19. Space shuttle Ram glow: Implication of NO2 recombination continuum

    NASA Astrophysics Data System (ADS)

    Swenson, G. R.; Mende, S. B.; Clifton, S.

    1985-09-01

    The ram glow data gathered to data from imaging experiments on space shuttle suggest the glow is a continuum (within 34 angstrom resolution); the continuum shape is such that the peak is near 7000 angstroms decreasing to the blue and red, and the average molecular travel leading to emission after leaving the surface is 20 cm (assuming isotropic scattering from the surface). Emission continuum is rare in molecular systems but the measured spectrum does resemble the laboratory spectrum of NO2 (B) recombination continuum. The thickness of the observed emission is consistent with the NO2 hypothesis given an exit velocity of approx. 2.5 km/sec (1.3 eV) which leaves approx. 3.7 eV of ramming OI energy available for unbonding the recombined NO2 from the surface. The NO2 is formed in a 3-body recombination of OI + NO + m = NO2 + m where OI originates from the atmosphere and NO is chemically formed on the surface from atmospheric NI and OI. The spacecraft surface then acts as the n for the reaction: Evidence exists from orbital mass spectrometer data that the NO and NO2 chemistry described in this process does occur on surfaces of spectrometer orifices in orbit. Surface temperature effects are likely a factor in the NO sticking efficiency and, therefore, glow intensities.

  20. Fiber-Optic Imaging Probe Developed for Space Used to Detect Diabetes Through the Eye

    NASA Technical Reports Server (NTRS)

    Ansari, Rafat R.; Chenault, Michelle V.; Datiles, Manuel B., III; Sebag, J.; Suh, Kwang I.

    2000-01-01

    Approximately 16 million Americans have diabetes mellitus, which can severely impair eyesight by causing cataracts, diabetic retinopathy, and glaucoma. Cataracts are 1.6 times more common in people with diabetes than in those without diabetes, and cataract extraction is the only surgical treatment. In many cases, diabetes-related ocular pathologies go undiagnosed until visual function is compromised. This ongoing pilot project seeks to study the progression of diabetes in a unique animal model by monitoring changes in the lens with a safe, sensitive, dynamic light-scattering probe. Dynamic light scattering (DLS), has the potential to diagnose cataracts at the molecular level. Recently, a new DLS fiber-optic probe was developed at the NASA Glenn Research Center at Lewis Field for noncontact, accurate, and extremely sensitive particle-sizing measurements in fluid dispersions and suspensions (ref. 1). This compact, portable, and rugged probe is free of optical alignment, offers point-and-shoot operation for various online field applications and challenging environments, and yet is extremely flexible in regards to sample container sizes, materials, and shapes. No external vibration isolation and no index matching are required. It can measure particles as small as 1 nm and as large as few micrometers in a wide concentration range from very dilute (waterlike) dispersions to very turbid (milklike) suspensions. It is safe and fast to use, since it only requires very low laser power (10 nW to 3 mW) with very short data acquisition times (2 to 10 sec).

  1. The Use of Langmuir Probes in Non-Maxwellian Space Plasmas

    NASA Technical Reports Server (NTRS)

    Hoegy, Walter R.; Brace, Larry H.

    1998-01-01

    Disturbance of the Maxwellian plasma may occur in the vicinity of a spacecraft due to photoemission, interactions between the spacecraft and thermospheric gases, or electron emissions from other devices on the spacecraft. Significant non-maxwellian plasma distributions may also occur in nature as a mixture of ionospheric and magnetospheric plasmas or secondaries produced by photoionization in the thermosphere or auroral precipitation. The general formulas for current collection (volt-ampere curves) by planar, cylindrical, and spherical Langmuir probes in isotropic and anisotropic non-maxwellian plasmas are examined. Examples are given of how one may identify and remove the non-maxwellian components in the Langmuir probe current to permit the ionospheric parameters to be determined. Theoretical volt-ampere curves presented for typical examples of non-maxwellian distributions include: two-temperature plasmas and a thermal plasma with an energetic electron beam. If the non-ionospheric electrons are Maxwellian at a temperature distinct from that of the ionosphere electrons, the volt-ampere curves can be fitted directly to obtain the temperatures and densities of both electron components without resorting to differenting the current. For an arbitrary isotropic distribution, the current for retarded particles is shown to be identical for the three geometries. For anisotropic distributions, the three probe geometries are not equally suited for measuring the ionospheric electron temperature and density or for determining the distribution function in the presence of non-maxwellian back-round electrons.

  2. RBE of radiations in space and the implications for space travel.

    PubMed

    Edwards, A A

    2001-01-01

    Space travellers are irradiated with cosmic rays to a dose rate considerably higher than that received on earth. In order to make sensible judgements about space exploration, the risks to health of such radiation need to be assessed. Part of the assessment of risk is to allow for the enhanced biological effectiveness of high LET radiations with respect to others. In space the high LET radiations of concern are high energy neutrons and charged particles. At the doses and dose rates encountered in space, the important risk is the induction of cancer in the astronauts. For this biological end-point there is no direct human evidence for the relative effectiveness of these radiations. There are some data for neutrons for cancer and life-shortening in laboratory animals but these are for fission spectra neutrons, which are of lower energy than those encountered in space. There is a small amount of data for protons and high energy heavier charged particles. The remaining evidence comes from cellular experiments observing chromosome aberrations and gene mutations. From this sparse information, pragmatic choices need to be made for application to protection in space. The data are reviewed and the bases for the pragmatic choices discussed.

  3. Ultrahigh-energy photons as probes of Lorentz symmetry violations in stringy space-time foam models.

    PubMed

    Maccione, Luca; Liberati, Stefano; Sigl, Günter

    2010-07-09

    The time delays between γ rays of different energies from extragalactic sources have often been used to probe quantum gravity models in which Lorentz symmetry is violated. It has been claimed that these time delays can be explained by or at least put the strongest available constraints on quantum gravity scenarios that cannot be cast within an effective field theory framework, such as the space-time foam, D-brane model. Here we show that this model would predict too many photons in the ultrahigh energy cosmic ray flux to be consistent with observations. The resulting constraints on the space-time foam model are much stronger than limits from time delays and allow for Lorentz violation effects way too small for explaining the observed time delays.

  4. Radial space potential measurements in the central cell of the tandem mirror experiment with a heavy-ion-beam probe

    SciTech Connect

    Hallock, G.A.

    1983-04-11

    Spatial and temporal profiles of the space potential in the central-cell midplane of TMX have been obtained with a heavy-ion-beam probe. The absolute accuracy of measurements is +- 25 volts (with respect to the machine vacuum walls) with a resolution of approx. 2 volts. During moderate fueling with the gas boxes (i/sub gas/ approx. = 1200 Atom-Amperes D/sub 2/), the plasma potential is parabolic to at least 25 cm radius, with phi/sub e/ approx. = phi/sub max/(1-(r/32)/sup 2/) and 300 < phi/sub max/ <450 volts. With puffer-valve fueling, the space potential is relatively flat to at least 27 cm radius, with 250 < phi/sub e/ < 350 volts.

  5. Environmental design implications for two deep space SmallSats

    NASA Astrophysics Data System (ADS)

    Kahn, Peter; Imken, Travis; Elliott, John; Sherwood, Brent; Frick, Andreas; Sheldon, Douglas; Lunine, Jonathan

    2017-10-01

    The extreme environmental challenges of deep space exploration force unique solutions to small satellite design in order to enable their use as scientifically viable spacecraft. The challenges of implementing small satellites within limited resources can be daunting when faced with radiation effects on delicate electronics that require shielding or unique adaptations for protection, or mass, power and volume limitations due to constraints placed by the carrier spacecraft, or even Planetary Protection compliant design techniques that drive assembly and testing. This paper will explore two concept studies where the environmental constraints and/or planetary protection mitigations drove the design of the Flight System. The paper will describe the key technical drivers on the Sylph mission concept to explore a plume at Europa as a secondary free-flyer as a part of the planned Europa Mission. Sylph is a radiation-hardened smallsat concept that would utilize terrain relative navigation to fly at low altitudes through a plume, if found, and relay the mass spectra data back through the flyby spacecraft during its 24-h mission. The second topic to be discussed will be the mission design constraints of the Near Earth Asteroid (NEA) Scout concept. NEAScout is a 6U cubesat that would utilize an 86 sq. m solar sail as propulsion to execute a flyby with a near-Earth asteroid and help retire Strategic Knowledge Gaps for future human exploration. NEAScout would cruise for 24 months to reach and characterize one Near-Earth asteroid that is representative of Human Exploration targets and telemeter that data directly back to Earth at the end of its roughly 2.5 year mission.

  6. Probing BoNT/A Protease Exosites: Implications for Inhibitor Design and Light Chain Longevity

    PubMed Central

    2015-01-01

    Botulinum neurotoxin serotype A (BoNT/A) is one of the most lethal toxins known. Its extreme toxicity is due to its light chain (LC), a zinc protease that cleaves SNAP-25, a synaptosome-associated protein, leading to the inhibition of neuronal activity. Studies on BoNT/A LC have revealed that two regions, termed exosites, can play an important role in BoNT catalytic activity. A clear understanding of how these exosites influence neurotoxin catalytic activity would provide a critical framework for deciphering the mechanism of SNAP-25 cleavage and the design of inhibitors. Herein, based on the crystallographic structure of BoNT/A LC complexed with its substrate, we designed an α-exosite binding probe. Experiments with this unique probe demonstrated that α-exosite binding enhanced both catalytic activity and stability of the LC. These data help delineate why α-exosite binding is needed for SNAP-25 cleavage and also provide new insights into the extended lifetime observed for BoNT/A LC in vivo. PMID:25295706

  7. Modeling the disequilibrium species for Jupiter and Saturn: Implications for Juno and Saturn entry probe

    NASA Astrophysics Data System (ADS)

    Wang, Dong; Lunine, Jonathan I.; Mousis, Olivier

    2016-09-01

    Disequilibrium species have been used previously to probe the deep water abundances and the eddy diffusion coefficient for giant planets. In this paper, we present a diffusion-kinetics code that predicts the abundances of disequilibrium species in the tropospheres of Jupiter and Saturn with updated thermodynamic and kinetic data. The dependence on the deep water abundance and the eddy diffusion coefficient is investigated. We quantified the disagreements in CO kinetics that comes from using different reaction networks and identified C2H6 as a useful tracer for the eddy diffusion coefficient. We first apply an H/P/O reaction network to Jupiter and Saturn's atmospheres and suggest a new PH3 destruction pathway. New chemical pathways for SiH4 and GeH4 destruction are also suggested, and another AsH3 destruction pathway is investigated thanks to new thermodynamic and kinetic data. These new models should enhance the interpretation of the measurement of disequilibrium species by JIRAM on board Juno and allow disentangling between methods for constraining the Saturn's deep water abundance with the Saturn entry probes envisaged by NASA or ESA.

  8. Acizzia solanicola (Hemiptera: Psyllidae) probing behaviour on two Solanum spp. and implications for possible pathogen spread

    PubMed Central

    Valenzuela, Isabel; Trebicki, Piotr; Powell, Kevin S.; Vereijssen, Jessica; Norng, Sorn

    2017-01-01

    Piercing-sucking insects are vectors of plant pathogens, and an understanding of their feeding behaviour is crucial for studies on insect population dynamics and pathogen spread. This study examines probing behaviour of the eggplant psyllid, Acizzia solanicola (Hemiptera: Psyllidae), using the electrical penetration graph (EPG) technique, on two widespread and common hosts: eggplant (Solanum melongena) and tobacco bush (S. mauritianum). Six EPG waveforms were observed: waveform NP (non-probing phase), waveform C (pathway phase), G (feeding activities in xylem tissues), D (first contact with phloem tissues), E1 (salivation in the sieve elements) and E2 (ingestion from phloem tissues). Results showed that A. solanicola is predominantly a phloem feeder and time spent in salivation and ingestion phases (E1 and E2) differed between hosts. Feeding was enhanced on eggplant compared to tobacco bush which showed some degree of resistance, as evidenced by shorter periods of phloem ingestion, a higher propensity to return to the pathway phase once in the sieve elements and higher number of salivation events on tobacco bush. We discuss how prolonged phloem feeding could indicate the potential for A. solanicola to become an important pest of eggplant and potential pathogen vector. PMID:28575085

  9. Modeling the disequilibrium species for Jupiter and Saturn: Implications for Juno and Saturn entry probe

    NASA Astrophysics Data System (ADS)

    Wang, D.; Lunine, J. I.; Mousis, O.

    2016-12-01

    Disequilibrium species have been used previously to probe the deep water abundances and the eddy diffusion coefficient for giant planets. In this abstract, we present a diffusion-kinetics code that predicts the abundances of disequilibrium species in the tropospheres of Jupiter and Saturn with updated thermodynamic and kinetic data. The dependence on the deep water abundance and the eddy diffusion coefficient is investigated. We quantified the disagreements in CO kinetics that comes from using different reaction networks and identified C2H6 as a useful tracer for the eddy diffusion coefficient. We first apply an H/P/O reaction network to Jupiter and Saturn's atmospheres and suggest a new PH3 destruction pathway. New chemical pathways for SiH4 and GeH4 destruction are also suggested, and another AsH3 destruction pathway is investigated thanks to new thermodynamic and kinetic data. These new models should enhance the interpretation of the measurement of disequilibrium species by JIRAM on board Juno and allow disentangling between methods for constraining the Saturn's deep water abundance with the Saturn entry probes envisaged by NASA or ESA.

  10. The Global Positioning System constellation as a space weather monitor. Comparison of electron measurements with Van Allen Probes data

    SciTech Connect

    Morley, Steven K.; Sullivan, John P.; Henderson, Michael G.; Blake, J. Bernard; Baker, Daniel N.

    2016-02-06

    Energetic electron observations in Earth's radiation belts are typically sparse, and multipoint studies often rely on serendipitous conjunctions. This paper establishes the scientific utility of the Combined X-ray Dosimeter (CXD), currently flown on 19 satellites in the Global Positioning System (GPS) constellation, by cross-calibrating energetic electron measurements against data from the Van Allen Probes. By breaking our cross calibration into two parts—one that removes any spectral assumptions from the CXD flux calculation and one that compares the energy spectra—we first validate the modeled instrument response functions, then the calculated electron fluxes. Unlike previous forward modeling of energetic electron spectra, we use a combination of four distributions that together capture a wide range of observed spectral shapes. Moreover, our two-step approach allowed us to identify, and correct for, small systematic offsets between block IIR and IIF satellites. Using the Magnetic Electron Ion Spectrometer and Relativistic Electron-Proton Telescope on Van Allen Probes as a “gold standard,” here we demonstrate that the CXD instruments are well understood. A robust statistical analysis shows that CXD and Van Allen Probes fluxes are similar and the measured fluxes from CXD are typically within a factor of 2 of Van Allen Probes at energies inline image4 MeV. Our team present data from 17 CXD-equipped GPS satellites covering the 2015 “St. Patrick's Day” geomagnetic storm to illustrate the scientific applications of such a high data density satellite constellation and therefore demonstrate that the GPS constellation is positioned to enable new insights in inner magnetospheric physics and space weather forecasting.

  11. The Global Positioning System constellation as a space weather monitor. Comparison of electron measurements with Van Allen Probes data

    DOE PAGES

    Morley, Steven K.; Sullivan, John P.; Henderson, Michael G.; ...

    2016-02-06

    Energetic electron observations in Earth's radiation belts are typically sparse, and multipoint studies often rely on serendipitous conjunctions. This paper establishes the scientific utility of the Combined X-ray Dosimeter (CXD), currently flown on 19 satellites in the Global Positioning System (GPS) constellation, by cross-calibrating energetic electron measurements against data from the Van Allen Probes. By breaking our cross calibration into two parts—one that removes any spectral assumptions from the CXD flux calculation and one that compares the energy spectra—we first validate the modeled instrument response functions, then the calculated electron fluxes. Unlike previous forward modeling of energetic electron spectra, wemore » use a combination of four distributions that together capture a wide range of observed spectral shapes. Moreover, our two-step approach allowed us to identify, and correct for, small systematic offsets between block IIR and IIF satellites. Using the Magnetic Electron Ion Spectrometer and Relativistic Electron-Proton Telescope on Van Allen Probes as a “gold standard,” here we demonstrate that the CXD instruments are well understood. A robust statistical analysis shows that CXD and Van Allen Probes fluxes are similar and the measured fluxes from CXD are typically within a factor of 2 of Van Allen Probes at energies inline image4 MeV. Our team present data from 17 CXD-equipped GPS satellites covering the 2015 “St. Patrick's Day” geomagnetic storm to illustrate the scientific applications of such a high data density satellite constellation and therefore demonstrate that the GPS constellation is positioned to enable new insights in inner magnetospheric physics and space weather forecasting.« less

  12. Human physiological adaptation to extended Space Flight and its implications for Space Station

    NASA Technical Reports Server (NTRS)

    Kutyna, F. A.; Shumate, W. H.

    1985-01-01

    Current work evaluating short-term space flight physiological data on the homeostatic changes due to weightlessness is presented as a means of anticipating Space Station long-term effects. An integrated systems analysis of current data shows a vestibulo-sensory adaptation within days; a loss of body mass, fluids, and electrolytes, stabilizing in a month; and a loss in red cell mass over a month. But bone demineralization which did not level off is seen as the biggest concern. Computer algorithms have been developed to simulate the human adaptation to weightlessness. So far these paradigms have been backed up by flight data and it is hoped that they will provide valuable information for future Space Station design. A series of explanatory schematics is attached.

  13. Human physiological adaptation to extended Space Flight and its implications for Space Station

    NASA Technical Reports Server (NTRS)

    Kutyna, F. A.; Shumate, W. H.

    1985-01-01

    Current work evaluating short-term space flight physiological data on the homeostatic changes due to weightlessness is presented as a means of anticipating Space Station long-term effects. An integrated systems analysis of current data shows a vestibulo-sensory adaptation within days; a loss of body mass, fluids, and electrolytes, stabilizing in a month; and a loss in red cell mass over a month. But bone demineralization which did not level off is seen as the biggest concern. Computer algorithms have been developed to simulate the human adaptation to weightlessness. So far these paradigms have been backed up by flight data and it is hoped that they will provide valuable information for future Space Station design. A series of explanatory schematics is attached.

  14. Improvements in Electron-Probe Microanalysis: Applications to Terrestrial, Extraterrestrial, and Space-Grown Materials

    NASA Technical Reports Server (NTRS)

    Carpenter, Paul; Armstrong, John

    2004-01-01

    Improvement in the accuracy of electron-probe microanalysis (EPMA) has been accomplished by critical assessment of standards, correction algorithms, and mass absorption coefficient data sets. Experimental measurement of relative x-ray intensities at multiple accelerating potential highlights errors in the absorption coefficient. The factor method has been applied to the evaluation of systematic errors in the analysis of semiconductor and silicate minds. Accurate EPMA of Martian soil stimulant is necessary in studies that build on Martian rover data in anticipation of missions to Mars.

  15. Leonid Shower Probe of Aerothermochemistry in Meteoric Plasmas and Implication for the Origin of Life

    NASA Technical Reports Server (NTRS)

    Jenniskens, Peter S. I.; Packan, D.; Laux, C.; Wilson, Mike; Boyd, I. D.; Kruger, C. H.; Popova, O.; Fonda, M.; DeVincenzi, Donald L. (Technical Monitor)

    2000-01-01

    The rarefied and high Mach number (up to 270) of the flow field of a typical meteoroid as it enters the Earth's atmosphere implies conditions of ablation and atmospheric chemistry that have proven to be as difficult to grasp as the proverbial shooting star. An airborne campaign was organized to study these processes during an intense Leonid shower. A probe of molecular band emission now demonstrates that the flash of light from a common meteor originates in the wake of the object rather than in the meteor head. A new theoretical approach using the direct simulation Monte Carlo technique demonstrates that the ablation process is critical in heating the air in that wake. Air molecules impinge on a dense cloud of ablated material in front of the meteoroid head into an extended wake that has the observed excitation temperatures. These processes determine what extraterrestrial materials may have been delivered to Earth at the time of the origin of life.

  16. Probing Galaxy Formation and Evolution with Space Born Sub-Millimeter Telescopes

    NASA Technical Reports Server (NTRS)

    Dwek, Eli; Arendt, Richard G.; Moseley, Harvey; Benford, Dominic; Shafer, Richard; Mather, John; Oegerle, William (Technical Monitor)

    2002-01-01

    A major unresolved question in cosmology is how the complex system of galaxies we see in the present universe evolved from an almost perfectly smooth beginning. Multiwavelength observations of galaxies have revealed that a significant fraction of their UV-visible starlight is absorbed and reradiated by dust at infrared JR) and submillimeter wavelengths. The cumulative IR-submm. emission from galaxies since the epoch of recombination, the cosmic IR background, has recently been recorded by the COBE satellite. The COBE observations in combination with recent submm surveys conducted with the SCUBA on the 15 m JCMT have shown that most of the radiation from star formation that has taken place in the early stages of galaxy evolution is reradiated by dust at submm wavelengths. Therefore, submm telescopes offer a unique probe of the early stages of galaxy formation and evolution. This talk will: (1) consider the impact of telescope diameter on the depth of the survey (what redshift can be probed) at different wavelengths; (2) discuss the relative scientific merits of high-resolution narrow-field surveys versus lower resolution deep surveys; and (3) show how both strategies offer complementary information crucial to our understanding of the structure and evolution of galaxies in the universe.

  17. Probing Galaxy Formation and Evolution with Space Born Sub-Millimeter Telescopes

    NASA Technical Reports Server (NTRS)

    Dwek, Eli; Arendt, Richard G.; Moseley, Harvey; Benford, Dominic; Shafer, Richard; Mather, John; Oegerle, William (Technical Monitor)

    2002-01-01

    A major unresolved question in cosmology is how the complex system of galaxies we see in the present universe evolved from an almost perfectly smooth beginning. Multiwavelength observations of galaxies have revealed that a significant fraction of their UV-visible starlight is absorbed and reradiated by dust at infrared JR) and submillimeter wavelengths. The cumulative IR-submm. emission from galaxies since the epoch of recombination, the cosmic IR background, has recently been recorded by the COBE satellite. The COBE observations in combination with recent submm surveys conducted with the SCUBA on the 15 m JCMT have shown that most of the radiation from star formation that has taken place in the early stages of galaxy evolution is reradiated by dust at submm wavelengths. Therefore, submm telescopes offer a unique probe of the early stages of galaxy formation and evolution. This talk will: (1) consider the impact of telescope diameter on the depth of the survey (what redshift can be probed) at different wavelengths; (2) discuss the relative scientific merits of high-resolution narrow-field surveys versus lower resolution deep surveys; and (3) show how both strategies offer complementary information crucial to our understanding of the structure and evolution of galaxies in the universe.

  18. Designing a space-based galaxy redshift survey to probe dark energy

    NASA Astrophysics Data System (ADS)

    Wang, Yun; Percival, Will; Cimatti, Andrea; Mukherjee, Pia; Guzzo, Luigi; Baugh, Carlton M.; Carbone, Carmelita; Franzetti, Paolo; Garilli, Bianca; Geach, James E.; Lacey, Cedric G.; Majerotto, Elisabetta; Orsi, Alvaro; Rosati, Piero; Samushia, Lado; Zamorani, Giovanni

    2010-12-01

    A space-based galaxy redshift survey would have enormous power in constraining dark energy and testing general relativity, provided that its parameters are suitably optimized. We study viable space-based galaxy redshift surveys, exploring the dependence of the Dark Energy Task Force (DETF) figure-of-merit (FoM) on redshift accuracy, redshift range, survey area, target selection and forecast method. Fitting formulae are provided for convenience. We also consider the dependence on the information used: the full galaxy power spectrum P(k), P(k) marginalized over its shape, or just the Baryon Acoustic Oscillations (BAO). We find that the inclusion of growth rate information (extracted using redshift space distortion and galaxy clustering amplitude measurements) leads to a factor of ~3 improvement in the FoM, assuming general relativity is not modified. This inclusion partially compensates for the loss of information when only the BAO are used to give geometrical constraints, rather than using the full P(k) as a standard ruler. We find that a space-based galaxy redshift survey covering ~20000deg2 over with σz/(1 + z) <= 0.001 exploits a redshift range that is only easily accessible from space, extends to sufficiently low redshifts to allow both a vast 3D map of the universe using a single tracer population, and overlaps with ground-based surveys to enable robust modelling of systematic effects. We argue that these parameters are close to their optimal values given current instrumental and practical constraints.

  19. FIB-SEM Tomography Probes the Mesoscale Pore Space of an Individual Catalytic Cracking Particle

    PubMed Central

    2016-01-01

    The overall performance of a catalyst particle strongly depends on the ability of mass transport through its pore space. Characterizing the three-dimensional structure of the macro- and mesopore space of a catalyst particle and establishing a correlation with transport efficiency is an essential step toward designing highly effective catalyst particles. In this work, a generally applicable workflow is presented to characterize the transport efficiency of individual catalyst particles. The developed workflow involves a multiscale characterization approach making use of a focused ion beam-scanning electron microscope (FIB-SEM). SEM imaging is performed on cross sections of 10.000 μm2, visualizing a set of catalyst particles, while FIB-SEM tomography visualized the pore space of a large number of 8 μm3 cubes (subvolumes) of individual catalyst particles. Geometrical parameters (porosity, pore connectivity, and heterogeneity) of the material were used to generate large numbers of virtual 3D volumes resembling the sample’s pore space characteristics, while being suitable for computationally demanding transport simulations. The transport ability, defined as the ratio of unhindered flow over hindered flow, is then determined via transport simulations through the virtual volumes. The simulation results are used as input for an upscaling routine based on an analogy with electrical networks, taking into account the spatial heterogeneity of the pore space over greater length scales. This novel approach is demonstrated for two distinct types of industrially manufactured fluid catalytic cracking (FCC) particles with zeolite Y as the active cracking component. Differences in physicochemical and catalytic properties were found to relate to differences in heterogeneities in the spatial porosity distribution. In addition to the characterization of existing FCC particles, our method of correlating pore space with transport efficiency does also allow for an up-front evaluation of

  20. KINETIC EVOLUTION OF CORONAL HOLE PROTONS BY IMBALANCED ION-CYCLOTRON WAVES: IMPLICATIONS FOR MEASUREMENTS BY SOLAR PROBE PLUS

    SciTech Connect

    Isenberg, Philip A.; Vasquez, Bernard J.

    2015-08-01

    We extend the kinetic guiding-center model of collisionless coronal hole protons presented in Isenberg and Vasquez to consider driving by imbalanced spectra of obliquely propagating ion-cyclotron waves. These waves are assumed to be a small by-product of the imbalanced turbulent cascade to high perpendicular wavenumber, and their total intensity is taken to be 1% of the total fluctuation energy. We also extend the kinetic solutions for the proton distribution function in the resulting fast solar wind to heliocentric distances of 20 solar radii, which will be attainable by the Solar Probe Plus spacecraft. We consider three ratios of outward-propagating to inward-propagating resonant intensities: 1, 4, and 9. The self-consistent bulk flow speed reaches fast solar wind values in all cases, and these speeds are basically independent of the intensity ratio. The steady-state proton distribution is highly organized into nested constant-density shells by the resonant wave-particle interaction. The radial evolution of this kinetic distribution as the coronal hole plasma flows outward is understood as a competition between the inward- and outward-directed large-scale forces, causing an effective circulation of particles through the (v{sub ∥}, v{sub ⊥}) phase space and a characteristic asymmetric shape to the distribution. These asymmetries are substantial and persist to the outer limit of the model computation, where they should be observable by the Solar Probe Plus instruments.

  1. Implications of the space radiation environment for human exploration in deep space.

    PubMed

    Townsend, Lawrence W

    2005-01-01

    Human exploration of the solar system beyond Earth's orbit will entail many risks for the crew on these deep space missions. One of the most significant health risks is exposure to the harsh space radiation environment beyond the protection provided by the Earth's intrinsic magnetic field. Crew on exploration missions will be exposed to a complex mixture of very energetic particles. Chronic exposures to the ever-present background galactic cosmic ray (GCR) spectrum consisting of all naturally occurring chemical elements are combined with sporadic, possibly acute exposures to large fluxes of solar energetic particles, mainly protons and alpha particles. The background GCR environment is mainly a matter of concern for stochastic effects, such as the induction of cancer with subsequent mortality in many cases, and late deterministic effects, such as cataracts and possible damage to the central nervous system. Unfortunately, the actual risks of cancer induction and mortality owing to the very important high-energy heavy ion component of the GCR spectrum are essentially unknown. The sporadic occurrence of extremely large solar energetic particle events (SPE), usually associated with intense solar activity, is also a major concern for the possible manifestation of acute effects from the accompanying high doses of such radiations, especially acute radiation syndrome effects such as nausea, emesis, haemorrhaging or, possibly, even death. In this presentation, an overview of the space radiation environment, estimates of the associated body organ doses and equivalent doses and the potential biological effects on crew in deep space are presented. Possible methods of mitigating these radiations, thereby reducing the associated risks to crew are also described.

  2. Considerations Affecting Satellite and Space Probe Research with Emphasis on the "Scout" as a Launch Vehicle

    NASA Technical Reports Server (NTRS)

    Posner, Jack (Editor)

    1961-01-01

    This report reviews a number of the factors which influence space flight experiments. Included are discussions of payload considerations, payload design and packaging, environmental tests, launch facilities, tracking and telemetry requirements, data acquisition, processing and analysis procedures, communication of information, and project management. Particular emphasis is placed on the "Scout" as a launching vehicle. The document includes a description of the geometry of the "Scout" as well as its flight capabilities and limitations. Although oriented toward the "Scout" vehicle and its payload capabilities, the information presented is sufficiently general to be equally applicable to most space vehicle systems.

  3. Contrasting Response of Two Dipolar Fluorescence Probes in a Leucine-Based Organogel and Its Implications.

    PubMed

    Soumya, Sivalingam; Seth, Sudipta; Paul, Sneha; Samanta, Anunay

    2015-08-03

    The microenvironments of a leucine-based organogel are probed by monitoring the fluorescence behavior of coumarin 153 (C153) and 4-aminophthalimide (AP). The steady-state data reveals distinctly different locations of the two molecules in the gel. Whereas AP resides close to the hydroxyl moieties of the gelator and engages in hydrogen-bonding interactions, C153 is found in bulk-toluene-like regions. In contrast to C153, AP exhibits excitation-wavelength-dependent emission, indicating that the environments of the hydrogen-bonded AP molecules are not all identical. A two-component fluorescence decay of AP in gel, unlike C153, supports this model. A time-resolved fluorescence anisotropy study of the rotational motion of the molecules also reveals the strong association of only AP with the gelator. That AP influences the critical gelation concentration implies its direct involvement in the gel-formation process. The results highlight the importance of guest-gelator interactions in gels containing guest molecules.

  4. Probing the Chemical Stability of Mixed Ferrites: Implications for MR Contrast Agent Design

    PubMed Central

    Schultz-Sikma, Elise A.; Joshi, Hrushikesh M.; Ma, Qing; MacRenaris, Keith W.; Eckermann, Amanda L.; Dravid, Vinayak P.; Meade, Thomas J.

    2011-01-01

    Nanomaterials with mixed composition, in particular magnetic spinel ferrites, are emerging as efficient contrast agents for magnetic resonance imaging (MRI). Many factors, including size, composition, atomic structure, and surface properties are crucial in the design of such nanoparticle-based probes due to their influence on the magnetic properties. Silica-coated iron oxide (IO-SiO2) and cobalt ferrite (CoIO-SiO2) nanoparticles were synthesized using standard high temperature thermal decomposition and base-catalyzed water-in-oil microemulsion techniques. Under neutral aqueous conditions, it was found that 50–75% of the cobalt content in the CoIO-SiO2 nanoparticles leached out of the core structure. Leaching caused a 7.2-fold increase in longitudinal relaxivity and an increase in the saturation magnetization from ~48 emu/g core to ~65 emu/g core. X-ray absorption fine structure studies confirmed that the atomic structure of the ferrite core was altered following leaching, while TEM and DLS confirmed that the morphology and size of the nanoparticle remained unchanged. The CoIO-SiO2 nanoparticles converted from a partially inverted spinel cation arrangement (unleached state) to an inverse spinel arrangement (leached state). The control IO-SiO2 nanoparticles remained stable with no change in structure and negligible changes in magnetic behavior. This detailed analysis highlights how important understanding the properties of nanomaterials is in the development of reliable agents for diagnostic and therapeutic applications. PMID:21603070

  5. Probing the Chemical Stability of Mixed Ferrites: Implications for MR Contrast Agent Design.

    PubMed

    Schultz-Sikma, Elise A; Joshi, Hrushikesh M; Ma, Qing; Macrenaris, Keith W; Eckermann, Amanda L; Dravid, Vinayak P; Meade, Thomas J

    2011-05-24

    Nanomaterials with mixed composition, in particular magnetic spinel ferrites, are emerging as efficient contrast agents for magnetic resonance imaging (MRI). Many factors, including size, composition, atomic structure, and surface properties are crucial in the design of such nanoparticle-based probes due to their influence on the magnetic properties. Silica-coated iron oxide (IO-SiO(2)) and cobalt ferrite (CoIO-SiO(2)) nanoparticles were synthesized using standard high temperature thermal decomposition and base-catalyzed water-in-oil microemulsion techniques. Under neutral aqueous conditions, it was found that 50-75% of the cobalt content in the CoIO-SiO(2) nanoparticles leached out of the core structure. Leaching caused a 7.2-fold increase in longitudinal relaxivity and an increase in the saturation magnetization from ~48 emu/g core to ~65 emu/g core. X-ray absorption fine structure studies confirmed that the atomic structure of the ferrite core was altered following leaching, while TEM and DLS confirmed that the morphology and size of the nanoparticle remained unchanged. The CoIO-SiO(2) nanoparticles converted from a partially inverted spinel cation arrangement (unleached state) to an inverse spinel arrangement (leached state). The control IO-SiO(2) nanoparticles remained stable with no change in structure and negligible changes in magnetic behavior. This detailed analysis highlights how important understanding the properties of nanomaterials is in the development of reliable agents for diagnostic and therapeutic applications.

  6. Ceruloplasmin (ferroxidase) oxidizes hydroxylamine probes: deceptive implications for free radical detection.

    PubMed

    Ganini, Douglas; Canistro, Donatella; Jiang, JinJie; Jang, JinJie; Stadler, Krisztian; Mason, Ronald P; Kadiiska, Maria B

    2012-10-01

    Ceruloplasmin (ferroxidase) is a copper-binding protein known to promote Fe(2+) oxidation in plasma of mammals. In addition to its classical ferroxidase activity, ceruloplasmin is known to catalyze the oxidation of various substrates, such as amines and catechols. Assays based on cyclic hydroxylamine oxidation are used to quantify and detect free radicals in biological samples ex vivo and in vitro. We show here that human ceruloplasmin promotes the oxidation of the cyclic hydroxylamine 1-hydroxy-3-carboxy-2,2,5,5-tetramethylpyrrolidine hydrochloride (CPH) and related probes in Chelex-treated phosphate buffer and rat serum. The reaction is suppressed by the metal chelators DTPA, EDTA, and desferal, whereas heparin and bathocuproine have no effect. Catalase or superoxide dismutase additions do not interfere with the CPH-oxidation yield, demonstrating that oxygen-derived free radicals are not involved in the CPH oxidation mediated by ceruloplasmin. Plasma samples immunodepleted of ceruloplasmin have lower levels of CPH oxidation, which confirms the role of ceruloplasmin (ferroxidase) as a biological oxidizing agent of cyclic hydroxylamines. In conclusion, we show that the ferroxidase activity of ceruloplasmin is a possible biological source of artifacts in the cyclic hydroxylamine-oxidation assay used for reactive oxygen species detection and quantification. Published by Elsevier Inc.

  7. Ceruloplasmin (ferroxidase) oxidizes hydroxylamine probes: deceptive implications for free radical detection

    PubMed Central

    Ganini, Douglas; Canistro, Donatella; Jang, JinJie; Stadler, Krisztian; Mason, Ronald P.; Kadiiska, Maria B.

    2012-01-01

    Ceruloplasmin (ferroxidase) is a copper-binding protein known to promote Fe2+ oxidation in plasma of mammals. Besides its classical ferroxidase activity, ceruloplasmin is known to catalyze the oxidation of various substrates, such as amines and catechols. Assays based on cyclic hydroxylamine oxidation are used to quantify and detect free radicals in biological samples ex vivo and in vitro. We show here that human ceruloplasmin promotes the oxidation of the cyclic hydroxylamine 1-hydroxy-3-carboxy-2,2,5,5-tetramethylpyrrolidine hydrochloride (CPH) and related probes in Chelex-treated phosphate buffer and rat serum. The reaction is suppressed by the metal chelators DTPA, EDTA and Desferal, while heparin and bathocuproine have no effect. Catalase or SOD additions do not interfere with the CPH-oxidation yield, demonstrating that free radicals are not involved in the CPH oxidation mediated by ceruloplasmin. Plasma samples immunodepleted of ceruloplasmin have lower levels of CPH oxidation, which confirms the role of ceruloplasmin (ferroxidase) as a biological oxidizing agent of cyclic hydroxylamines. In conclusion, we show that the ferroxidase activity of ceruloplasmin is a possible biological source of artifacts in the cyclic hydroxylamine-oxidation assay used for ROS detection and quantification. PMID:22824865

  8. The Role Played by Space-based Probes in our Understanding of the Cosmos

    NASA Astrophysics Data System (ADS)

    Macchetto, Ferdinando Duccio

    Over the last fifteen years a growing fleet of modern space-based astronomical telescopes has changed drastically our view of the universe. Most of these accomplishments build upon the work of ground-based astronomers over many decades, or even centuries. The combination of telescopes observing the universe at many different wavelengths has converted many prior hypotheses, for which supporting empirical data were scant, ambiguous and painfully difficult to obtain, into clearly and decisively demonstrated truth. But space observatories have gone well beyond that. In particular the Hubble Space Telescope with its combination of sharp images and deep dynamic range, has provided a detailed view of the unimagined complexity and diversity of the universe, as well as its startling beauty. It has yielded numerous surprises and raised new fundamental questions on the basic structure and laws that govern the universe. To answer these questions will require the efforts of ground-based and new space-based observatories working in combined programs over many years. In my talk I will illustrate some of the key discoveries that these space-based observatories have made such as: the deep imaging the distant universe; the calibration of the distance scale and the determination of the age of the universe; the discovery of the acceleration of the expansion rate of the universe, which requires a "dark energy" or new physics to explain it; the detection and measurement of supermassive black holes and the solution to the long standing problem of the nature of Quasars; the solution to the problem of whether Gamma Ray sources originated in our galaxy or at cosmological distances; the renewed interest in the problem of the birth of Stars and the formation of Planetary Systems; the death of Stars and the formation of supernovae, black holes and neutron stars and last but not least the exciting studies of the planets and satellites in our own dynamic solar system

  9. Implications for Earth and space in new K-12 science standards

    NASA Astrophysics Data System (ADS)

    Wysession, Michael E.

    2012-11-01

    New science standards for national K-12 science education are in the process of being written by a states-led team of writers organized by Achieve, Inc., with important implications for teaching Earth and space sciences. The final version of these "Next Generation Science Standards" (NGSS) is scheduled to be released in early 2013, but a second draft of the standards will be made public in December 2012. Members of the Earth and space science (ESS) research communities can review this draft of NGSS and provide constructive feedback. Such feedback will help ensure that American students receive instruction that is accurate, relevant, and engaging.

  10. Application of Compressive Sensing to Gravitational Microlensing Data and Implications for Miniaturized Space Observatories

    NASA Technical Reports Server (NTRS)

    Korde-Patel, Asmita (Inventor); Barry, Richard K.; Mohsenin, Tinoosh

    2016-01-01

    Compressive Sensing is a technique for simultaneous acquisition and compression of data that is sparse or can be made sparse in some domain. It is currently under intense development and has been profitably employed for industrial and medical applications. We here describe the use of this technique for the processing of astronomical data. We outline the procedure as applied to exoplanet gravitational microlensing and analyze measurement results and uncertainty values. We describe implications for on-spacecraft data processing for space observatories. Our findings suggest that application of these techniques may yield significant, enabling benefits especially for power and volume-limited space applications such as miniaturized or micro-constellation satellites.

  11. The space density of magnetic and non-magnetic cataclysmic variables, and implications for CV evolution

    NASA Astrophysics Data System (ADS)

    Pretorius, M.

    2014-07-01

    I will present estimates of the space densities of both non-magnetic and magnetic cataclysmic variables (CVs), based on X-ray flux-limited samples. The measurements can be used to address several questions relevant to the evolution of CVs and to the makeup of Galactic X-ray source populations. I will discuss the implications of these results for the high predicted space density of non-magnetic CVs, the evolutionary relationship between intermediate polars and polars, the fraction of CVs with strongly magnetic white dwarfs, and for the contribution of magnetic CVs to Galactic populations of hard X-ray sources.

  12. Gravity Probe B Inspection

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The space vehicle Gravity Probe B (GP-B) is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. In this photograph, engineer Gary Reynolds is inspecting the inside of the probe neck during probe thermal repairs. GP-B is scheduled for launch in April 2004 and managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Leese, Gravity Probe B, Stanford University)

  13. Probing the Chemical Stability of Mixed Ferrites: Implications for Magnetic Resonance Contrast Agent Design

    SciTech Connect

    Schultz-Sikma, Elise A.; Joshi, Hrushikesh M.; Ma, Qing; MacRenaris, Keith W.; Eckermann, Amanda L.; Dravid, Vinayak P.; Meade, Thomas J.

    2011-09-16

    Nanomaterials with mixed composition, in particular magnetic spinel ferrites, are emerging as efficient contrast agents for magnetic resonance imaging. Many factors, including size, composition, atomic structure, and surface properties, are crucial in the design of such nanoparticle-based probes because of their influence on the magnetic properties. Silica-coated iron oxide (IO-SiO{sub 2}) and cobalt ferrite (CoIO-SiO{sub 2}) nanoparticles were synthesized using standard high-temperature thermal decomposition and base-catalyzed water-in-oil microemulsion techniques. Under neutral aqueous conditions, it was found that 50-75% of the cobalt content in the CoIO-SiO{sub 2} nanoparticles leached out of the core structure. Leaching caused a 7.2-fold increase in the longitudinal relaxivity and an increase in the saturation magnetization from {approx}48 to {approx}65 emu/g of the core. X-ray absorption fine structure studies confirmed that the atomic structure of the ferrite core was altered following leaching, while transmission electron microscopy and dynamic light scattering confirmed that the morphology and size of the nanoparticle remained unchanged. The CoIO-SiO{sub 2} nanoparticles converted from a partially inverted spinel cation arrangement (unleached state) to an inverse spinel arrangement (leached state). The control IO-SiO{sub 2} nanoparticles remained stable with no change in the structure and negligible changes in the magnetic behavior. This detailed analysis highlights how important understanding the properties of nanomaterials is in the development of reliable agents for diagnostic and therapeutic applications.

  14. Space adaptation syndrome: Incidence and operational implications for the space transportation system program

    NASA Technical Reports Server (NTRS)

    Homick, J. L.; Reschke, M. F.; Vanderploeg, J. M.

    1984-01-01

    Better methods for the prediction, prevention, and treatment of the space adaptation syndome (SAS) were developed. A systematic, long range program of operationally oriented data collection on all individuals flying space shuttle missions was initiated. Preflight activities include the use of a motion experience questionnaire, laboratory tests of susceptibility to motion sickness induced by Coriolis stimuli and determinations of antimotion sickness drug efficacy and side effects. During flight, each crewmember is required to provide a daily report of symptom status, use of medications, and other vestibular related sensations. Additional data are obtained postflight. During the first nine shuttle missions, the reported incidence of SAS has been48%. Self-induced head motions and unusual visual orientation attitudes appear to be the principal triggering stimuli. Antimotion sickness medication, was of limited therapeutic value. Complete recovery from symptoms occurred by mission day three or four. Also of relevance is the lack of a statistically significant correlation between the ground based Coriolis test and SAS. The episodes of SAS have resulted in no impact to shuttle mission objectives and, no significant impact to mission timelines.

  15. Probing space charge and resolving overlimiting current mechanisms at the microchannel-nanochannel interface

    NASA Astrophysics Data System (ADS)

    Schiffbauer, Jarrod; Liel, Uri; Leibowitz, Neta; Park, Sinwook; Yossifon, Gilad

    2015-07-01

    We present results demonstrating the space charge-mediated transition between classical, diffusion-limited current and surface-conduction dominant over-limiting current in a shallow microchannel-nanochannel device. The extended space charge layer develops at the depleted microchannel-nanochannel entrance at high current and is correlated with a distinctive maximum in the dc resistance. Experimental results for a shallow surface-conduction dominated system are compared with theoretical models, allowing estimates of the effective surface charge at high voltage to be obtained. In comparison to an equilibrium estimate of the surface charge obtained from electrochemical impedance spectroscopy, it is further observed that the effective surface charge appears to change under applied voltage.

  16. Probing space charge and resolving overlimiting current mechanisms at the microchannel-nanochannel interface.

    PubMed

    Schiffbauer, Jarrod; Liel, Uri; Leibowitz, Neta; Park, Sinwook; Yossifon, Gilad

    2015-07-01

    We present results demonstrating the space charge-mediated transition between classical, diffusion-limited current and surface-conduction dominant over-limiting current in a shallow microchannel-nanochannel device. The extended space charge layer develops at the depleted microchannel-nanochannel entrance at high current and is correlated with a distinctive maximum in the dc resistance. Experimental results for a shallow surface-conduction dominated system are compared with theoretical models, allowing estimates of the effective surface charge at high voltage to be obtained. In comparison to an equilibrium estimate of the surface charge obtained from electrochemical impedance spectroscopy, it is further observed that the effective surface charge appears to change under applied voltage.

  17. A comment on "the far future of exoplanet direct characterization"--the case for interstellar space probes.

    PubMed

    Crawford, Ian A

    2010-10-01

    Following on from ideas presented in a recent paper by Schneider et al. on "The Far Future of Exoplanet Direct Characterization," I argue that they have exaggerated the technical obstacles to performing such "direct characterization" by means of fast (order 0.1c) interstellar space probes. A brief summary of rapid interstellar spaceflight concepts that may be found in the literature is presented. I argue that the presence of interstellar dust grains, while certainly something that will need to be allowed for in interstellar vehicle design, is unlikely to be the kind of showstopper suggested by Schneider et al. Astrobiology as a discipline would be a major beneficiary of developing an interstellar spaceflight capability, albeit in the longer term, and I argue that astrobiologists should keep an open mind to the possibilities.

  18. Reciprocal space XRD mapping with varied incident angle as a probe of structure variation within surface depth

    SciTech Connect

    Yang, Qiguang; Williams, Frances; Zhao, Xin; Reece, Charles E.; Krishnan, Mahadevan

    2013-09-01

    In this study, we used a differential-depth X-Ray diffraction Reciprocal Spacing Mapping (XRD RSM) technique to investigate the crystal quality of a variety of SRF-relevant Nb film and bulk materials. By choosing different X-ray probing depths, the RSM study successfully revealed evolution the of materials microstructure after different materials processes, such as energetic condensation or surface polishing. The RSM data clearly measured the materials crystal quality at different thickness. Through a novel differential-depth RSM technique, this study found: I. for a heteroepitaxy Nb film Nb(100)/MgO(100), the film thickening process, via a cathodic arc-discharge Nb ion deposition, created a near-perfect single crystal Nb on the surfaces top-layer; II. for a mechanically polished single-crystal bulk Nb material, the microstructure on the top surface layer is more disordered than that in-grain.

  19. Payload test philosophy. [implications of STS development at Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Arman, A.

    1979-01-01

    The implications of STS development for payload testing at the Goddard Space Flight Center are reviewed. The biggest impact of STS may be that instead of testing the entire payload, most of the testing may have to be limited to the subsystem or subassembly level. Particular consideration is given to the Goddard protoflight concept in which the test is geared to the design qualification levels, the test durations being those that are expected during the actual launch sequence.

  20. Payload test philosophy. [implications of STS development at Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Arman, A.

    1979-01-01

    The implications of STS development for payload testing at the Goddard Space Flight Center are reviewed. The biggest impact of STS may be that instead of testing the entire payload, most of the testing may have to be limited to the subsystem or subassembly level. Particular consideration is given to the Goddard protoflight concept in which the test is geared to the design qualification levels, the test durations being those that are expected during the actual launch sequence.

  1. Debris Disk Science Enabled by a Probe-scale Space Coronagraph Mission

    NASA Astrophysics Data System (ADS)

    Stapelfeldt, Karl R.; Trauger, J. T.; Krist, J. E.

    2010-01-01

    Debris disks are the signposts of planetary systems: collisions between rocky/icy parent bodies maintain debris dust around main sequence stars against losses to radiation pressure and P-R drag. Debris disk structures show the location of asteroid/Kuiper belts around nearby stars, and reflect dynamical interactions with local extrasolar planets. Only 17 debris disks with high optical depth have been spatially resolved to date in scattered light images made with the Hubble Space Telescope and ground-based adaptive optics. Hundreds more with lower optical depth have been identified among nearby stars through far-IR photometry with the Spitzer Space Telescope, and more should follow in the next few years from Herschel. The most capable means for imaging this larger disk population is a next-generation coronagraphic instrument on a 1.5m class optical space telescope. Utilizing high-contrasat imaging simulations validated by laboratory demonstrations on the JPL High Contrast Imaging Testbed, we show that such a mission will be capable of imaging Kuiper disk structures down to the 10 zodi level, and exozodiacal dust down to the 1 zodi level, around a major sample of nearby stars. This performance goes well beyond what is about to be achieved with upcoming extreme adaptive optics systems or the ALMA array, and thus provides the best path for imaging exploration of planetary systems in the solar neighborhood.

  2. Probing the Allende meteorite with a miniature laser-ablation mass analyser for space application

    NASA Astrophysics Data System (ADS)

    Neuland, M. B.; Meyer, S.; Mezger, K.; Riedo, A.; Tulej, M.; Wurz, P.

    2014-10-01

    We measured the elemental composition on a sample of Allende meteorite with a miniature laser ablation mass spectrometer. This laser mass spectrometer (LMS) has been designed and built at the University of Bern in the Department of Space Research and Planetary Sciences with the objective of using such an instrument on a space mission. Utilising the meteorite Allende as the test sample in this study, it is demonstrated that the instrument allows the in situ determination of the elemental composition and thus mineralogy and petrology of untreated rocky samples, particularly on planetary surfaces. In total, 138 measurements of elemental compositions have been carried out on an Allende sample. The mass spectrometric data are evaluated and correlated with an optical image. It is demonstrated that by illustrating the measured elements in the form of mineralogical maps, LMS can serve as an element imaging instrument with a very high spatial resolution of μm scale. The detailed analysis also includes a mineralogical evaluation and an investigation of the volatile element content of Allende. All findings are in good agreement with published data and underline the high sensitivity, accuracy and capability of LMS as a mass analyser for space exploration.

  3. Full data acquisition in Kelvin Probe Force Microscopy: Mapping dynamic electric phenomena in real space

    NASA Astrophysics Data System (ADS)

    Collins, Liam; Belianinov, Alex; Somnath, Suhas; Balke, Nina; Kalinin, Sergei V.; Jesse, Stephen

    2016-08-01

    Kelvin probe force microscopy (KPFM) has provided deep insights into the local electronic, ionic and electrochemical functionalities in a broad range of materials and devices. In classical KPFM, which utilizes heterodyne detection and closed loop bias feedback, the cantilever response is down-sampled to a single measurement of the contact potential difference (CPD) per pixel. This level of detail, however, is insufficient for materials and devices involving bias and time dependent electrochemical events; or at solid-liquid interfaces, where non-linear or lossy dielectrics are present. Here, we demonstrate direct recovery of the bias dependence of the electrostatic force at high temporal resolution using General acquisition Mode (G-Mode) KPFM. G-Mode KPFM utilizes high speed detection, compression, and storage of the raw cantilever deflection signal in its entirety at high sampling rates. We show how G-Mode KPFM can be used to capture nanoscale CPD and capacitance information with a temporal resolution much faster than the cantilever bandwidth, determined by the modulation frequency of the AC voltage. In this way, G-Mode KPFM offers a new paradigm to study dynamic electric phenomena in electroactive interfaces as well as a promising route to extend KPFM to the solid-liquid interface.

  4. Full data acquisition in Kelvin Probe Force Microscopy: Mapping dynamic electric phenomena in real space

    PubMed Central

    Collins, Liam; Belianinov, Alex; Somnath, Suhas; Balke, Nina; Kalinin, Sergei V.; Jesse, Stephen

    2016-01-01

    Kelvin probe force microscopy (KPFM) has provided deep insights into the local electronic, ionic and electrochemical functionalities in a broad range of materials and devices. In classical KPFM, which utilizes heterodyne detection and closed loop bias feedback, the cantilever response is down-sampled to a single measurement of the contact potential difference (CPD) per pixel. This level of detail, however, is insufficient for materials and devices involving bias and time dependent electrochemical events; or at solid-liquid interfaces, where non-linear or lossy dielectrics are present. Here, we demonstrate direct recovery of the bias dependence of the electrostatic force at high temporal resolution using General acquisition Mode (G-Mode) KPFM. G-Mode KPFM utilizes high speed detection, compression, and storage of the raw cantilever deflection signal in its entirety at high sampling rates. We show how G-Mode KPFM can be used to capture nanoscale CPD and capacitance information with a temporal resolution much faster than the cantilever bandwidth, determined by the modulation frequency of the AC voltage. In this way, G-Mode KPFM offers a new paradigm to study dynamic electric phenomena in electroactive interfaces as well as a promising route to extend KPFM to the solid-liquid interface. PMID:27514987

  5. Full data acquisition in Kelvin Probe Force Microscopy: Mapping dynamic electric phenomena in real space.

    PubMed

    Collins, Liam; Belianinov, Alex; Somnath, Suhas; Balke, Nina; Kalinin, Sergei V; Jesse, Stephen

    2016-08-12

    Kelvin probe force microscopy (KPFM) has provided deep insights into the local electronic, ionic and electrochemical functionalities in a broad range of materials and devices. In classical KPFM, which utilizes heterodyne detection and closed loop bias feedback, the cantilever response is down-sampled to a single measurement of the contact potential difference (CPD) per pixel. This level of detail, however, is insufficient for materials and devices involving bias and time dependent electrochemical events; or at solid-liquid interfaces, where non-linear or lossy dielectrics are present. Here, we demonstrate direct recovery of the bias dependence of the electrostatic force at high temporal resolution using General acquisition Mode (G-Mode) KPFM. G-Mode KPFM utilizes high speed detection, compression, and storage of the raw cantilever deflection signal in its entirety at high sampling rates. We show how G-Mode KPFM can be used to capture nanoscale CPD and capacitance information with a temporal resolution much faster than the cantilever bandwidth, determined by the modulation frequency of the AC voltage. In this way, G-Mode KPFM offers a new paradigm to study dynamic electric phenomena in electroactive interfaces as well as a promising route to extend KPFM to the solid-liquid interface.

  6. Availability of feature-oriented scanning probe microscopy for remote-controlled measurements on board a space laboratory or planet exploration Rover.

    PubMed

    Lapshin, Rostislav V

    2009-06-01

    Prospects for a feature-oriented scanning (FOS) approach to investigations of sample surfaces, at the micrometer and nanometer scales, with the use of scanning probe microscopy under space laboratory or planet exploration rover conditions, are examined. The problems discussed include decreasing sensitivity of the onboard scanning probe microscope (SPM) to temperature variations, providing autonomous operation, implementing the capabilities for remote control, self-checking, self-adjustment, and self-calibration. A number of topical problems of SPM measurements in outer space or on board a planet exploration rover may be solved via the application of recently proposed FOS methods.

  7. 1958 NASA/USAF Space Probes (Able-1). Volume 1; Summary

    NASA Technical Reports Server (NTRS)

    1959-01-01

    Early in calendar year 1958 Space Technology Laboratories, Inc. (STL) (then Space Technology Laboratories, a division of the Ramo-Wooldridge Corp.) developed for the Air Force Ballistic Missile Division (AFBMD) an Advanced Re-entry Test Vehicle (ARTV) for the purpose of testing ballistic missile nose cones at the full range of 5500 nautical miles. The two-stage ARTV utilized the Thor ballistic missile and the second stage propulsion system developed for the Vanguard program. In late 1957 and early 1958, STL/AFBMD prepared studies of various missile combinations which could be utilized for space testing. The Thor, in combination with the Vanguard second and third stages, was one of the vehicles considered which offered a very early capability of placing a reasonable payload in a lunar orbit. These STL/AFBMD studies were presented to various appropriate groups including the Killian, Millikan, H. J . Stewart Committees; Headquarters, Air Research and Development Command, and ARDC Centers. Subsequently the Advanced Research Projects Agency (ARPA) contacted STL relative to the availability of hardware for an early lunar shot. By utilizing existing spares already purchased for the ARTV, and by making use of the ARTV contractors already in being, it appeared feasible to launch by the third quarter of calendar year 1958 a payload which would be captured by the moon's gravitational force. On 27 March 1958, ARPA directed STL to proceed with a program of three lunar shots. As much as possible, these shots were to utilize existing ARTV spare hardware and impose no interference with the ballistic missile programs. In September this program was transferred to the direction of the National Aeronautics and Space Administration (NASA). On 17 August 1958 the first launching of the Able-1 vehicle was attempted, but the flight was terminated by a propulsion failure of the first stage. Subsequent launchings were attempted on 13 October and 8 November 1958. Of these launchirigs the

  8. Full data acquisition in Kelvin Probe Force Microscopy: Mapping dynamic electric phenomena in real space

    SciTech Connect

    Balke, Nina; Kalinin, Sergei V.; Jesse, Stephen; Collins, Liam; Belianinov, Alex; Somnath, Suhas

    2016-08-12

    Kelvin probe force microscopy (KPFM) has provided deep insights into the role local electronic, ionic and electrochemical processes play on the global functionality of materials and devices, even down to the atomic scale. Conventional KPFM utilizes heterodyne detection and bias feedback to measure the contact potential difference (CPD) between tip and sample. This measurement paradigm, however, permits only partial recovery of the information encoded in bias- and time-dependent electrostatic interactions between the tip and sample and effectively down-samples the cantilever response to a single measurement of CPD per pixel. This level of detail is insufficient for electroactive materials, devices, or solid-liquid interfaces, where non-linear dielectrics are present or spurious electrostatic events are possible. Here, we simulate and experimentally validate a novel approach for spatially resolved KPFM capable of a full information transfer of the dynamic electric processes occurring between tip and sample. General acquisition mode, or G-Mode, adopts a big data approach utilising high speed detection, compression, and storage of the raw cantilever deflection signal in its entirety at high sampling rates (> 4 MHz), providing a permanent record of the tip trajectory. We develop a range of methodologies for analysing the resultant large multidimensional datasets involving classical, physics-based and information-based approaches. Physics-based analysis of G-Mode KPFM data recovers the parabolic bias dependence of the electrostatic force for each cycle of the excitation voltage, leading to a multidimensional dataset containing spatial and temporal dependence of the CPD and capacitance channels. We use multivariate statistical methods to reduce data volume and separate the complex multidimensional data sets into statistically significant components that can then be mapped onto separate physical mechanisms. Overall, G-Mode KPFM offers a new paradigm to study dynamic

  9. Full data acquisition in Kelvin Probe Force Microscopy: Mapping dynamic electric phenomena in real space

    DOE PAGES

    Balke, Nina; Kalinin, Sergei V.; Jesse, Stephen; ...

    2016-08-12

    Kelvin probe force microscopy (KPFM) has provided deep insights into the role local electronic, ionic and electrochemical processes play on the global functionality of materials and devices, even down to the atomic scale. Conventional KPFM utilizes heterodyne detection and bias feedback to measure the contact potential difference (CPD) between tip and sample. This measurement paradigm, however, permits only partial recovery of the information encoded in bias- and time-dependent electrostatic interactions between the tip and sample and effectively down-samples the cantilever response to a single measurement of CPD per pixel. This level of detail is insufficient for electroactive materials, devices, ormore » solid-liquid interfaces, where non-linear dielectrics are present or spurious electrostatic events are possible. Here, we simulate and experimentally validate a novel approach for spatially resolved KPFM capable of a full information transfer of the dynamic electric processes occurring between tip and sample. General acquisition mode, or G-Mode, adopts a big data approach utilising high speed detection, compression, and storage of the raw cantilever deflection signal in its entirety at high sampling rates (> 4 MHz), providing a permanent record of the tip trajectory. We develop a range of methodologies for analysing the resultant large multidimensional datasets involving classical, physics-based and information-based approaches. Physics-based analysis of G-Mode KPFM data recovers the parabolic bias dependence of the electrostatic force for each cycle of the excitation voltage, leading to a multidimensional dataset containing spatial and temporal dependence of the CPD and capacitance channels. We use multivariate statistical methods to reduce data volume and separate the complex multidimensional data sets into statistically significant components that can then be mapped onto separate physical mechanisms. Overall, G-Mode KPFM offers a new paradigm to study

  10. Probing the Depths of Space Weathering: A Cross-sectional View of Lunar Rock 76015

    NASA Technical Reports Server (NTRS)

    Noble, Sarah K.; Keller, L. P.; Stroud, Rhonda

    2007-01-01

    The term "space weathering" refers to the cumulative effects of several processes operating at the surface of any solar system body not protected by a thick atmosphere. These processes include cosmic and solar ray irradiation, solar wind implantation and sputtering, as well as melting and vaporization due to micrometeorite bombardment. Space weathering discussions have generally centered around soils but exposed rocks will also incur the effects of weathering. Rocks have much longer surface lifetimes than an individual soil grain and thus record a longer history of exposure. By studying the weathering products which have built up on a rock surface, we can gain a deeper perspective on the weathering process and better assess the relative importance of various weathering components. The weathered coating, or patina, of the lunar rock 76015 has been previously studied using SEM and TEM. It is a noritic breccia with both "glazed" (smooth glassy) and "classic" (microcratered and pancake-bearing) patina coatings. Previous TEM work on 76015 relied on ultramicrotomy to prepare cross sections of the patina coating, but these sections were limited by the "chatter" and loss of material in these brittle samples. Here we have used a focused ion beam (FIB) instrument to prepare cross sections in which the delicate stratigraphy of the patina coating is beautifully preserved.

  11. Probing the noncommutative effects of phase space in the time-dependent Aharonov-Bohm effect

    NASA Astrophysics Data System (ADS)

    Ma, Kai; Wang, Jian-Hua

    2017-08-01

    We study the noncommutative corrections on the time-dependent Aharonov-Bohm effect when both the coordinate-coordinate and momentum-momentum noncommutativities are considered. On the noncommutative phase space, while the ordinary gauge symmetry can be kept by the Seiberg-Witten map, but the Lorentz symmetry is broken. Therefore nontrivial noncommutative corrections are expected. We find there are three kinds of noncommutative corrections in general: (1) ξ-dependent correction which comes from the noncommutativity among momentum operators; (2) momentum-dependent correction which is rooted in the nonlocal interactions in the noncommutative extended model; (3) momentum-independent correction which emerges become of the gauge invariant condition on the nonlocal interactions in the noncommutative model. We proposed two dimensionless quantities, which are based on the distributions of the measured phase shift with respect to the external magnetic field and to the cross section enclosed by the particle trajectory, to extract the noncommutative parameters. We find that stronger (weaker) magnetic field strength can give better bounds on the coordinate-coordinate (momentum-momentum) noncommutative parameter, and large parameter space region can be explored by the time-dependent AB effect.

  12. Probing quantum state space: does one have to learn everything to learn something?

    PubMed

    Carmeli, Claudio; Heinosaari, Teiko; Schultz, Jussi; Toigo, Alessandro

    2017-05-01

    Determining the state of a quantum system is a consuming procedure. For this reason, whenever one is interested only in some particular property of a state, it would be desirable to design a measurement set-up that reveals this property with as little effort as possible. Here, we investigate whether, in order to successfully complete a given task of this kind, one needs an informationally complete measurement, or if something less demanding would suffice. The first alternative means that in order to complete the task, one needs a measurement which fully determines the state. We formulate the task as a membership problem related to a partitioning of the quantum state space and, in doing so, connect it to the geometry of the state space. For a general membership problem, we prove various sufficient criteria that force informational completeness, and we explicitly treat several physically relevant examples. For the specific cases that do not require informational completeness, we also determine bounds on the minimal number of measurement outcomes needed to ensure success in the task.

  13. Flight Experience from Space Photovoltaic Concentrator Arrays and its Implication on Terrestrial Concentrator Systems

    NASA Technical Reports Server (NTRS)

    Piszczor, Michael F., Jr.

    2003-01-01

    Nearly all photovoltaic solar arrays flown in space have used a planar (non- concentrating) design. However, there have been a few notable exceptions where photovoltaic concentrators have been tested and used as the mission s primary power source. Among these are the success experienced by the SCARLET (Solar Concentrator Array with Refractive Linear Element Technology) concept used to power NASA's Deep Space 1 mission and the problems encountered by the original Boeing 702 reflective trough concentrator design. This presentation will give a brief overview of past photovoltaic concentrator systems that have flown in space, specifically addressing the valuable lessons learned from flight experience, and other viable concentrator concepts that are being proposed for the future. The general trends of this flight experience will be noted and discussed with regard to its implications on terrestrial photovoltaic concentrator designs.

  14. Implications of privacy needs and interpersonal distancing mechanisms for space station design

    NASA Technical Reports Server (NTRS)

    Harrison, A. A.; Sommer, R.; Struthers, N.; Hoyt, K.

    1985-01-01

    Privacy needs, or the need of people to regulate their degree of contact with one another, and interpersonal distancing mechanisms, which serve to satisfy these needs, are common in all cultures. Isolation, confinement, and other conditions accociated with space flight may at once accentuate privacy needs and limit the availability of certain common interpersonal contact. Loneliness occurs when people have less contact with one another than they desire. Crowding occurs when people have more contact with one another than they desire. Crowding, which is considered the greater threat to members of isolated and confined groups, can contribute to stress, a low quality of life, and poor performance. Drawing on the general literature on privacy, personal space, and interpersonal distancing, and on specialized literature on life aboard spacecraft and in spacecraft-analogous environments, a quantitative model for understanding privacy, interpersonal distancing, loneliness, and crowding was developed and the practical implications of this model for space station design were traced.

  15. Quasar emission lines as probes of orientation: implications for disc wind geometries and unification

    NASA Astrophysics Data System (ADS)

    Matthews, J. H.; Knigge, C.; Long, K. S.

    2017-01-01

    The incidence of broad absorption lines (BALs) in quasar samples is often interpreted in the context of a geometric unification model consisting of an accretion disc and an associated outflow. We use the the Sloan Digital Sky Survey (SDSS) quasar sample to test this model by examining the equivalent widths (EWs) of C IV 1550 Å, Mg II 2800 Å, [O III] 5007 Å and C III] 1909 Å. We find that the emission line EW distributions in BAL and non-BAL quasars are remarkably similar - a property that is inconsistent with scenarios in which a BAL outflow rises equatorially from a geometrically thin, optically thick accretion disc. We construct simple models to predict the distributions from various geometries; these models confirm the above finding and disfavour equatorial geometries. We show that obscuration, line anisotropy and general relativistic effects on the disc continuum are unlikely to hide an EW inclination dependence. We carefully examine the radio and polarisation properties of BAL quasars. Both suggest that they are most likely viewed (on average) from intermediate inclinations, between type 1 and type 2 AGN. We also find that the low-ionization BAL quasars in our sample are not confined to one region of `Eigenvector I' parameter space. Overall, our work leads to one of the following conclusions, or some combination thereof: (i) the continuum does not emit like a geometrically thin, optically thick disc; (ii) BAL quasars are viewed from similar angles to non-BAL quasars, i.e. low inclinations; (iii) geometric unification does not explain the fraction of BALs in quasar samples.

  16. Quasar emission lines as probes of orientation: implications for disc wind geometries and unification

    NASA Astrophysics Data System (ADS)

    Matthews, J. H.; Knigge, C.; Long, K. S.

    2017-05-01

    The incidence of broad absorption lines (BALs) in quasar samples is often interpreted in the context of a geometric unification model consisting of an accretion disc and an associated outflow. We use the Sloan Digital Sky Survey quasar sample to test this model by examining the equivalent widths (EWs) of C iv 1550 Å, Mg ii 2800 Å, [O iii] 5007 Å and C iii] 1909 Å. We find that the emission line EW distributions in BAL and non-BAL quasars are remarkably similar - a property that is inconsistent with scenarios in which a BAL outflow rises equatorially from a geometrically thin, optically thick accretion disc. We construct simple models to predict the distributions from various geometries; these models confirm the above finding and disfavour equatorial geometries. We show that obscuration, line anisotropy and general relativistic effects on the disc continuum are unlikely to hide an EW inclination dependence. We carefully examine the radio and polarization properties of BAL quasars. Both suggest that they are most likely viewed (on average) from intermediate inclinations, between type 1 and type 2 active galactic nuclei (AGN). We also find that the low-ionization BAL quasars in our sample are not confined to one region of the 'Eigenvector 1' parameter space. Overall, our work leads to one of the following conclusions, or some combination thereof: (i) the continuum does not emit like a geometrically thin, optically thick disc; (ii) BAL quasars are viewed from similar angles to non-BAL quasars, that is, low inclinations and (iii) geometric unification does not explain the fraction of BALs in quasar samples.

  17. Ozone probe: UV whiskbroom scanning spectroradiometer for earth albedo measurements from space

    NASA Astrophysics Data System (ADS)

    Talmor, Eli T.

    1993-08-01

    An UV spectro-radiometer operating in the 0.24 - 0.30 micrometers spectral region is being devised for Earth albedo measurements from space aboard the TECHSAT-1 satellite. The sensor incorporates a four-element, wide FOV (14 degree(s)) optic with an interference wedge as a spectral dispersive element. The spatial and spectral scanning is accomplished using a single CsTe cathode photomultiplier operating in the photon-counting mode. The sensor is capable of a 2 mrad spatial and 0.01 micrometers spectral resolution. The sensor is intended to measure the Earth backscattering albedo. The spectral profile of the albedo is a function of the ozone vertical distribution. The scientific goal of this project is to investigate the long-term impact of Kuwaiti oil fires on the stratosphere above the Middle East region. An additional goal is to find out the extent of global ozone depletion over the Middle East.

  18. k-space image correlation to probe the intracellular dynamics of gold nanoparticles

    NASA Astrophysics Data System (ADS)

    Bouzin, M.; Sironi, L.; Chirico, G.; D'Alfonso, L.; Inverso, D.; Pallavicini, P.; Collini, M.

    2016-04-01

    The collective action of dynein, kinesin and myosin molecular motors is responsible for the intracellular active transport of cargoes, vesicles and organelles along the semi-flexible oriented filaments of the cytoskeleton. The overall mobility of the cargoes upon binding and unbinding to motor proteins can be modeled as an intermittency between Brownian diffusion in the cell cytoplasm and active ballistic excursions along actin filaments or microtubules. Such an intermittent intracellular active transport, exhibited by star-shaped gold nanoparticles (GNSs, Gold Nanostars) upon internalization in HeLa cancer cells, is investigated here by combining live-cell time-lapse confocal reflectance microscopy and the spatio-temporal correlation, in the reciprocal Fourier space, of the acquired image sequences. At first, the analytical theoretical framework for the investigation of a two-state intermittent dynamics is presented for Fourier-space Image Correlation Spectroscopy (kICS). Then simulated kICS correlation functions are employed to evaluate the influence of, and sensitivity to, all the kinetic and dynamic parameters the model involves (the transition rates between the diffusive and the active transport states, the diffusion coefficient and drift velocity of the imaged particles). The optimal procedure for the analysis of the experimental data is outlined and finally exploited to derive whole-cell maps for the parameters underlying the GNSs super-diffusive dynamics. Applied here to the GNSs subcellular trafficking, the proposed kICS analysis can be adopted for the characterization of the intracellular (super-) diffusive dynamics of any fluorescent or scattering biological macromolecule.

  19. Approaches for probing the sequence space of substrates recognized by molecular chaperones

    PubMed Central

    Kota, Pradeep; Dokholyan, Nikolay V.

    2011-01-01

    Neurodegeneration, the progressive loss of function in neurons that eventually leads to their death, is the cause of many neurodegenerative disorders including Alzheimer’s, Parkinson’s, and Huntington’s diseases. Protein aggregation is a hallmark of most neurodegenerative diseases, where unfolded proteins form intranuclear, cytosolic, and extracellular insoluble aggregates in neurons. Mounting evidence from studies in neurodegenerative disease models shows that molecular chaperones, key regulators of protein aggregation and degradation, play critical roles in the progression of neurodegeneration. Although chaperones exhibit promiscuity in their substrate specificity, specific molecular features are required for substrate recognition. Understanding the basis for substrate recognition by chaperones will aid in the development of therapeutic strategies that regulate chaperone expression levels in order to combat neurodegeneration. Many experimental techniques, including alanine scanning mutagenesis and phage display library screening, have been developed and applied to understand the basis of substrate recognition by chaperones. Here, we present computational algorithms that can be applied to rapidly screen the sequence space of potential substrates to determine the sequence and structural requirements for substrate recognition by chaperones. PMID:21195183

  20. Approaches for probing the sequence space of substrates recognized by molecular chaperones.

    PubMed

    Kota, Pradeep; Dokholyan, Nikolay V

    2011-03-01

    Neurodegeneration, the progressive loss of function in neurons that eventually leads to their death, is the cause of many neurodegenerative disorders including Alzheimer's, Parkinson's, and Huntington's diseases. Protein aggregation is a hallmark of most neurodegenerative diseases, where unfolded proteins form intranuclear, cytosolic, and extracellular insoluble aggregates in neurons. Mounting evidence from studies in neurodegenerative disease models shows that molecular chaperones, key regulators of protein aggregation and degradation, play critical roles in the progression of neurodegeneration. Although chaperones exhibit promiscuity in their substrate specificity, specific molecular features are required for substrate recognition. Understanding the basis for substrate recognition by chaperones will aid in the development of therapeutic strategies that regulate chaperone expression levels in order to combat neurodegeneration. Many experimental techniques, including alanine scanning mutagenesis and phage display library screening, have been developed and applied to understand the basis of substrate recognition by chaperones. Here, we present computational algorithms that can be applied to rapidly screen the sequence space of potential substrates to determine the sequence and structural requirements for substrate recognition by chaperones. Copyright © 2010 Elsevier Inc. All rights reserved.

  1. Gravity field estimation from future space missions - TOPEX/POSEIDON, Gravity Probe B, and ARISTOTELES

    NASA Technical Reports Server (NTRS)

    Pavlis, Erricos C.

    1992-01-01

    Accurate knowledge of the gravity field is a firm requirement in any study of Planet Earth. Space techniques have so far demonstrated their superiority in the global mapping of the gravity field based on ground tracking and altimeter data mostly. Numerical and analytical simulation studies of the upcoming geophysically relevant missions that will most likely carry GPS receivers, indicate significant improvements in the accuracy as well as the resolution of the gravity field. TOPEX will improve by some two orders of magnitude the long wavelength part (to degree about 20), while GP-B will contribute in the long as well as medium wavelength part of the spectrum (up to degree about 60). The gradiometer measurements on ARISTOTELES will contribute in the medium and short wavelength regions (from degree 30 up); GPS tracking of the spacecraft though will provide additional information for the long wavelength gravity and will help resolve it to accuracies comparable to those obtained from GP-B. With the mean rms coefficient error per degree kept below 10 exp -10, geophysical signals such as the post-glacial rebound, tidal variations, and secular and periodic variations of the zonal field rise above the noise level and become readily observable processes.

  2. Gravity field estimation from future space missions - TOPEX/POSEIDON, Gravity Probe B, and ARISTOTELES

    NASA Astrophysics Data System (ADS)

    Pavlis, Erricos C.

    Accurate knowledge of the gravity field is a firm requirement in any study of Planet Earth. Space techniques have so far demonstrated their superiority in the global mapping of the gravity field based on ground tracking and altimeter data mostly. Numerical and analytical simulation studies of the upcoming geophysically relevant missions that will most likely carry GPS receivers, indicate significant improvements in the accuracy as well as the resolution of the gravity field. TOPEX will improve by some two orders of magnitude the long wavelength part (to degree about 20), while GP-B will contribute in the long as well as medium wavelength part of the spectrum (up to degree about 60). The gradiometer measurements on ARISTOTELES will contribute in the medium and short wavelength regions (from degree 30 up); GPS tracking of the spacecraft though will provide additional information for the long wavelength gravity and will help resolve it to accuracies comparable to those obtained from GP-B. With the mean rms coefficient error per degree kept below 10 exp -10, geophysical signals such as the post-glacial rebound, tidal variations, and secular and periodic variations of the zonal field rise above the noise level and become readily observable processes.

  3. Gravity field estimation from future space missions - TOPEX/POSEIDON, Gravity Probe B, and ARISTOTELES

    NASA Technical Reports Server (NTRS)

    Pavlis, Erricos C.

    1992-01-01

    Accurate knowledge of the gravity field is a firm requirement in any study of Planet Earth. Space techniques have so far demonstrated their superiority in the global mapping of the gravity field based on ground tracking and altimeter data mostly. Numerical and analytical simulation studies of the upcoming geophysically relevant missions that will most likely carry GPS receivers, indicate significant improvements in the accuracy as well as the resolution of the gravity field. TOPEX will improve by some two orders of magnitude the long wavelength part (to degree about 20), while GP-B will contribute in the long as well as medium wavelength part of the spectrum (up to degree about 60). The gradiometer measurements on ARISTOTELES will contribute in the medium and short wavelength regions (from degree 30 up); GPS tracking of the spacecraft though will provide additional information for the long wavelength gravity and will help resolve it to accuracies comparable to those obtained from GP-B. With the mean rms coefficient error per degree kept below 10 exp -10, geophysical signals such as the post-glacial rebound, tidal variations, and secular and periodic variations of the zonal field rise above the noise level and become readily observable processes.

  4. Tone-Based Command of Deep Space Probes using Ground Antennas

    NASA Technical Reports Server (NTRS)

    Bokulic, Robert S.; Jensen, J. Robert

    2008-01-01

    A document discusses a technique for enabling the reception of spacecraft commands at received signal levels as much as three orders of magnitude below those of current deep space systems. Tone-based commanding deals with the reception of commands that are sent in the form of precise frequency offsets using an open-loop receiver. The key elements of this technique are an ultrastable oscillator and open-loop receiver onboard the spacecraft, both of which are part of the existing New Horizons (Pluto flyby) communications system design. This enables possible flight experimentation for tone-based commanding during the long cruise of the spacecraft to Pluto. In this technique, it is also necessary to accurately remove Doppler shift from the uplink signal presented to the spacecraft. A signal processor in the spacecraft performs a discrete Fourier transform on the received signal to determine the frequency of the received signal. Due to the long-term drift in the oscillators and orbit prediction model, the system is likely to be implemented differentially, where changes in the uplink frequency convey the command information.

  5. New developments at Hunveyor and Husar space probe model constructions in Hungarian Universities and Colleges: status report of 2008

    NASA Astrophysics Data System (ADS)

    Hegzi, S.; Bérczi, Sz.; Hudoba, Gy.; Magyar, I.; Lang, A.; Istenes, Z.; Weidinger, T.; Tepliczky, I.; Varga, T.; Hargitai, H.

    2008-09-01

    Introduction Hunveyor and Husar space probe models are the main school robotics program in Hungary in the last decade initiated by our Cosmic Materials Space research Group (CMSRG). As a new form of planetary science education in Hungary students build their lander and rover robots and test them on test tables, carry out simulations, and go with their instruments to field works of planetary geology analog sites. Recently 10 groups work in this program and here is a status report about the new results. Planetary robot construction and simulations steps We summarized in 10 steps the main "constructional and industrial research and technology" description of planetary material studying and collecting by space probes (landers, rovers). We focused on the activity we began and teach to carry out at those steps. (Main planets considered were the Moon and Mars): 1. Reconnaissance and survey of the surface of a planet by orbital space probes (i.e. Lunar Orbiter, MGS, MRO etc.) Our studies: photogeology, geomorphology, preparations to cartography. 2. Mapping of the surface of the selected planet with geographical and stratigraphical methods. We (CMSRG) prepared thematic maps on Moon, Mercury, Mars, Venus [1] and Atlas (3) in the series [2,3]. 3. Identification of various surface materials by albedo, spectroscopic [4], thermal IR, identification and selection of the target sites. (in terrestrial analog sites during field works) 4. Planning the space probe system lander and rover working together (MPF-Sojourner type assembly). Planning of the Hunveyor and Husar models. 5. Construction and manufacturing lander and rover units. All Hunveyor groups built their models [5]. 6. Launching and traveling the space probes to the planetary surface. (No rocket building, we simulate [6] some events during the voyage only). 7. Measuring the planetary surface environment on the surface of target planet [7]. (CMSRG) groups carry out test-table measurements [8] and simulations, and later they

  6. Space/age forestry: Implications of planting density and rotation age in SRIC management decisions

    SciTech Connect

    Merriam, R.A.; Phillips, V.D.; Liu, W.

    1993-12-31

    Short-rotation intensive-culture (SRIC) of promising tree crops is being evaluated worldwide for the production of methanol, ethanol, and electricity from renewable biomass resources. Planting density and rotation age are fundamental management decisions associated with SRIC energy plantations. Most studies of these variables have been conducted without the benefit of a unifying theory of the effects of growing space and rotation age on individual tree growth and stand level productivity. A modeling procedure based on field trials of Eucalyptus spp. is presented that evaluates the growth potential of a tree in the absence and presence of competition of neighboring trees in a stand. The results of this analysis are useful in clarifying economic implications of different growing space and rotation age decisions that tree plantation managers must make. The procedure is readily applicable to other species under consideration for SRIC plantations at any location.

  7. Space Physics of Close-in Exoplanets and its Implications for Planet Habitability

    NASA Astrophysics Data System (ADS)

    Cohen, Ofer

    2015-04-01

    The search for habitable exoplanets is currently focused on planets orbiting M-dwarf stars, due to the close proximity of the habitable zone to the star. However, the traditional habitability definition does not account for the physical space environment near the planets, which can be extreme at close-in orbits, and can lead to erosion of te planetary atmosphere. In order to sustain their atmosphers, M-dwarf planets need to have either an intrinsic magnetic field, or a thick atmosphere. Here we present a set of numerical magnetohydrodynamic simulations of the interaction of an Earth-like magnetized planet and a Venus-like non-magnetized planet with the stellar wind of M-dwarf star. We study space physics aspects of these interactions and their implications for planet habitability

  8. Future Mission Trends and their Implications for the Deep Space Network

    NASA Technical Reports Server (NTRS)

    Abraham, Douglas S.

    2006-01-01

    Planning for the upgrade and/or replacement of Deep Space Network (DSN) assets that typically operate for forty or more years necessitates understanding potential customer needs as far into the future as possible. This paper describes the methodology Deep Space Network (DSN) planners use to develop this understanding, some key future mission trends that have emerged from application of this methodology, and the implications of the trends for the DSN's future evolution. For NASA's current plans out to 2030, these trends suggest the need to accommodate: three times as many communication links, downlink rates two orders of magnitude greater than today's, uplink rates some four orders of magnitude greater, and end-to-end link difficulties two-to-three orders of magnitude greater. To meet these challenges, both DSN capacity and capability will need to increase.

  9. Heavy ions, radioprotectors and genomic instability: implications for human space exploration.

    PubMed

    Dziegielewski, Jaroslaw; Goetz, Wilfried; Baulch, Janet E

    2010-08-01

    The risk associated with space radiation exposure is unique from terrestrial radiation exposures due to differences in radiation quality, including linear energy transfer (LET). Both high- and low-LET radiations are capable of inducing genomic instability in mammalian cells, and this instability is thought to be a driving force underlying radiation carcinogenesis. Unfortunately, during space exploration, flight crews cannot entirely avoid radiation exposure. As a result, chemical and biological countermeasures will be an important component of successful extended missions such as the exploration of Mars. There are currently several radioprotective agents (radioprotectors) in use; however, scientists continue to search for ideal radioprotective compounds-safe to use and effective in preventing and/or reducing acute and delayed effects of irradiation. This review discusses the agents that are currently available or being evaluated for their potential as radioprotectors. Further, this review discusses some implications of radioprotection for the induction and/or propagation of genomic instability in the progeny of irradiated cells.

  10. In-situ exploration of planetary upper atmospheres with balloons ejected from sounding rockets and space probes

    NASA Astrophysics Data System (ADS)

    Danielides, Michael; Griebel, Hannes; Bayler, Klaus; Herholz, J.

    Balloon missions have been used extensively on Earth to study a large variety of atmospheric characteristics and phenomena. Of primary interest are in situ temperature, pressure and density profiles and wind velocities. The first planetary balloons were flown in the mid 1980s with the Vega 1 and 2 missions to Venus. Since then, balloons have been further developed and planed for, e.g., Mars and Titan. Testing those technologies first on Earth made sense because Earths upper (neutral) atmosphere provides many similarities to Mars atmosphere. The aim of this presentation is to provide a brief overview of the current state in scientific ballooning, and in particular report on the expertise obtained through the MIRIAM (Main Inflated Re-entry Into the Atmosphere Mission Test) Mars balloon near space deployment experiments. The test ballute MIRIAM was flown on board a REXUS 4 sounding rocket from ESRANGE in northern Sweden on October 22nd, 2008. The balloon was deployed at about 140 km altitude. On board were optical instruments, magnetometers, temperature sensors and barometers for atmospheric studies. The data gathered during decent was used to validate inflation, deployment concepts and planetary balloon technologies. Based on those results a new ballute probe MIRIAM-2 is under construction. Its aim is the recording atmospheric parameters which will be then compared to Earth upper atmospheric models. Finally, we address and discuss future prospects for balloon in situ exploration of Mars atmosphere.

  11. Encapsulated guest-host dynamics: guest rotational barriers and tumbling as a probe of host interior cavity space.

    PubMed

    Mugridge, Jeffrey S; Szigethy, Géza; Bergman, Robert G; Raymond, Kenneth N

    2010-11-17

    The supramolecular host assembly [Ga(4)L(6)](12-) (1; L = 1,5-bis[2,3-dihydroxybenzamido]naphthalene) encapsulates cationic guest molecules within its hydrophobic cavity and catalyzes a variety of chemical transformations within its confined interior space. Despite the well-defined structure, the host ligand framework and interior cavity are very flexible and 1 can accommodate a wide range of guest shapes and sizes. These observations raise questions about the steric effects of confinement within 1 and how encapsulation fundamentally changes the motions of guest molecules. Here we examine the motional dynamics (guest bond rotation and tumbling) of encapsulated guest molecules to probe the steric consequences of encapsulation within host 1. Encapsulation is found to increase the Ph-CH(2) bond rotational barrier for ortho-substituted benzyl phosphonium guest molecules by 3 to 6 kcal/mol, and the barrier is found to depend on both guest size and shape. The tumbling dynamics of guests encapsulated in 1 were also investigated, and here it was found that longer, more prolate-shaped guest molecules tumble more slowly in the host cavity than larger but more spherical guest molecules. The prolate guests reduce the host symmetry from T to C(1) in solution at low temperatures, and the distortion of the host framework that is in part responsible for this symmetry reduction is observed directly in the solid state. Analysis of guest motional dynamics is a powerful method for interrogating host structure and fundamental host-guest interactions.

  12. Nanopore-based DNA-probe sequence-evolution method unveiling characteristics of protein-DNA binding phenomena in a nanoscale confined space.

    PubMed

    Liu, Nannan; Yang, Zekun; Lou, Xiaoding; Wei, Benmei; Zhang, Juntao; Gao, Pengcheng; Hou, Ruizuo; Xia, Fan

    2015-04-07

    Almost all of the important functions of DNA are realized by proteins which interact with specific DNA, which actually happens in a limited space. However, most of the studies about the protein-DNA binding are in an unconfined space. Here, we propose a new method, nanopore-based DNA-probe sequence-evolution (NDPSE), which includes up to 6 different DNA-probe systems successively designed in a nanoscale confined space which unveil the more realistic characteristics of protein-DNA binding phenomena. There are several features; for example, first, the edge-hindrance and core-hindrance contribute differently for the binding events, and second, there is an equilibrium between protein-DNA binding and DNA-DNA hybridization.

  13. Implications of previous space commercialization experiences for the reusable launch vehicle

    NASA Astrophysics Data System (ADS)

    Obermann, Richard M.; Williamson, Ray A.

    2003-07-01

    The United States' 1994 National Space Transportation Policy directed the National Aeronautics and Space Administration (NASA) to work with industry on the development of technologies required for a reusable launch vehicle (RLV). In the partnership that has evolved from that directive, NASA envisions its role as providing support for technological risk reduction and for developing space transportation to serve government needs. NASA officials assume that the development of an operational, commercial RLV will be carried out by the private sector without use of government funds. Under that scenario, the Federal government will simply become a customer for commercial RLV services. In evaluating the prospects for the development of a commercially viable RLV, it may be useful to examine "lessons learned" from previous space commercialization efforts—both those that succeeded and those that did not. It can be argued that several distinct streams of market and technological development may have to converge for successful commercialization of space systems to occur. Potential factors influencing the prospects for commercialization include the size and growth rate of the potential customer base, the extent to which a governmental customer exists to underpin the market, the development of associated "value-added" markets, the stability of governmental policies, the levels of technological and business risk, and the degree to which competitive markets exist. This paper examines two previous space commercialization experiences, evaluates the relative importance of the various factors that influence the prospects for success of commercialization efforts, and assesses the implications of those factors for the commercial viability of the proposed RLV.

  14. Technological implications of SNAP reactor power system development on future space nuclear power systems

    SciTech Connect

    Anderson, R.V.

    1982-11-16

    Nuclear reactor systems are one method of satisfying space mission power needs. The development of such systems must proceed on a path consistent with mission needs and schedules. This path, or technology roadmap, starts from the power system technology data base available today. Much of this data base was established during the 1960s and early 1970s, when government and industry developed space nuclear reactor systems for steady-state power and propulsion. One of the largest development programs was the Systems for Nuclear Auxiliary Power (SNAP) Program. By the early 1970s, a technology base had evolved from this program at the system, subsystem, and component levels. There are many implications of this technology base on future reactor power systems. A review of this base highlights the need for performing a power system technology and mission overview study. Such a study is currently being performed by Rockwell's Energy Systems Group for the Department of Energy and will assess power system capabilities versus mission needs, considering development, schedule, and cost implications. The end product of the study will be a technology roadmap to guide reactor power system development.

  15. Investigation of the properties of the autonomous optical navigation of a space probe during rendezvous with an asteroid

    NASA Astrophysics Data System (ADS)

    Ivashkin, V. V.

    1990-11-01

    The determination of the planetocentric coordinates of a spacecraft flying by an asteroid and of a probe separated from the spaceraft for rendezvous with the asteroid is considered. It is shown that sighting of the planet on the star background makes possible the accurate evaluation of the spacecraft and probe positions with respect to the asteroid. The results obtained suggest that autonomous optical navigation can be used to guide a probe for landing on a planet.

  16. Observed Coupling Between the International Space Station PCU Plasma and a FPMU Langmuir Probe Facilitated by the Geomagnetic Field

    NASA Technical Reports Server (NTRS)

    Hartman, William; Koontz, Steven L.

    2010-01-01

    Electrical charging of the International Space Station (ISS) is a matter of serious concern resulting from the possibility of vehicle arcing and electrical shock hazard to crew during extravehicular activity (EVA). A Plasma Contactor Unit (PCU) was developed and integrated into ISS in order to control the ISS floating potential, thereby, minimize vehicle charging and associated hazards. One of the principle factors affecting ISS electrical charging is the ionosphere plasma state (i.e., electron temperature and density). To support ISS electrical charging studies a Floating Potential Monitoring Unit (FPMU) is also integrated into ISS in order to measure the ionosphere properties using Langmuir probes (LP). The FPMU was located on the Starboard side of ISS. The PCU is located near the center of ISS with its plasma exhaust pointed to port. From its integration on ISS in 2006 through November of 2009, the FPMU data exhibited nominal characteristics during PCU operation. On November 21, 2009 the FPMU was relocated from the Starboard location to a new Port location. After relocation significant enhanced noise was observed in both the LP current-voltage sweeps and the derived electron temperature data. The enhanced noise only occurred when the PCU was in discharge and at unique and repeatable locations of the ISS orbit. The cause of this enhanced noise was investigated. It was found that there is coupling occurring between the PCU plasma and the FPMU LP. In this paper we shall 1) present the on-orbit data and the presence of enhanced noise, 2) demonstrate that the coupling of the PCU plasma and the FPMU measurements is geomagnetically organized, 3) show that coupling of the PCU plasma and the FPMU is primarily due to and driven by particle-wave interaction and 4) show that the ionosphere conditions are adequate for Alfven waves to be generated by the PCU plasma.

  17. Implications of privacy needs and interpersonal distancing mechanisms for space station design

    NASA Technical Reports Server (NTRS)

    Harrison, Albert A.; Sommer, Robert; Struthers, Nancy; Hoyt, Kathleen

    1988-01-01

    Isolation, confinement, and the characteristics of microgravity will accentuate the need for privacy in the proposed NASA space station, yet limit the mechanism available for achieving it. This study proposes a quantitative model for understanding privacy, interpersonal distancing, and performance, and discusses the practical implications for Space Station design. A review of the relevant literature provided the basis for a database, definitions of physical and psychological distancing, loneliness, and crowding, and a quantitative model of situational privacy. The model defines situational privacy (the match between environment and task), and focuses on interpersonal contact along visual, auditory, olfactory, and tactile dimensions. It involves summing across pairs of crew members, contact dimensions, and time, yet also permits separate analyses of subsets of crew members and contact dimensions. The study concludes that performance will benefit when the type and level of contact afforded by the environment align with that required by the task. The key to achieving this is to design a flexible, definable, and redefinable interior environment that provides occupants with a wide array of options to meet their needs for solitude, limited social interaction, and open group activity. The report presents 49 recommendations in five categories to promote a wide range of privacy options despite the space station's volumetric limitations.

  18. Suitability of digoxin as a P-glycoprotein probe: implications of other transporters on sensitivity and specificity.

    PubMed

    Nader, Ahmed M; Foster, David R

    2014-01-01

    The study of transporter-mediated drug-drug interactions (DDI) requires use of appropriate probes to reflect transporter function. Digoxin is often used as a probe in DDI studies involving P-glycoprotein (P-gp) and is recommended by FDA for this purpose, despite several lingering questions regarding suitability of digoxin as P-gp probe. This review aims to critically evaluate use of digoxin as a probe for P-gp-mediated clinical DDI studies, with focus on sensitivity and specificity of digoxin for P-gp. Although previous reviews have evaluated digoxin transport by P-gp, the purpose of the current review is to critically evaluate such literature in light of newly evolving literature suggesting digoxin transport by non-P-gp transporters.

  19. Magnetic Cloud Bz solar cycle variation and the space weather implications

    NASA Astrophysics Data System (ADS)

    Li, Y.; Luhmann, J. G.; Jian, L.; Russell, C. T.

    2016-12-01

    The relationship between magnetic cloud (MC) polarity and the solar magnetic field polarity cycle is extended up to the present. In spite of the weak solar polar fields, the related complications of helmet streamer belt and source surface neutral line over the recent solar cycle, the MC polarity solar cycle variation pattern continues to be true. A trend related to the long solar minimum between cycles 23 and 24are longer periods of N-S polarity MCs. The MC polarity patterns at the STEREO sites generally reflect that at L1. Combining the MC events at three observing points (L1 and STEREO A&B) provides a larger data sample, and the normalized result reenforce and clarify the MC polarity trend. We conclude with some discussions regarding source regions and space weather implications.

  20. Gravity Probe B Encapsulated

    NASA Technical Reports Server (NTRS)

    2004-01-01

    In this photo, the Gravity Probe B (GP-B) space vehicle is being encapsulated atop the Delta II launch vehicle. The GP-B is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Underwood, Lockheed Martin Corporation).

  1. Gravity Probe B Encapsulated

    NASA Technical Reports Server (NTRS)

    2004-01-01

    In this photo, the Gravity Probe B (GP-B) space vehicle is being encapsulated atop the Delta II launch vehicle. The GP-B is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Underwood, Lockheed Martin Corporation).

  2. Subglacial clast behaviour and its implication for till fabric development: new results derived from wireless subglacial probe experiments

    NASA Astrophysics Data System (ADS)

    Hart, Jane K.; Rose, Kathryn C.; Martinez, Kirk; Ong, Royan

    2009-04-01

    This study has investigated the three-dimensional movement of clasts within deformation till, using embedded wireless probes. These probes were part of an environmental sensor network, which measured subglacial properties (temperature, water pressure, resistivity, case strain and tilt) six times a day, and relayed that data via radio to the glacier surface, where they were forwarded and broadcast on-line. The system was installed at Briksdalsbreen, Norway and operated from August 2004 until August 2006. Approximately 2000 probe days worth of data were collected, with an increase in performance (41% more readings) during the second year. The probes showed similar patterns of water pressure rises throughout the two years, but with slightly different magnitudes and timings. These changes in water pressure could be related to clast behaviour. The probes decreased their dip over the year, and the rate of change was related to an increase in glacier velocity. After initial changes in dip, the probes experienced changes in orientation, followed by rotation about the a-axis. This continuous rotation was similar to the motion suggested by Jeffery [1922. The motion of ellipsoidal particles immersed in a viscous fluid. Proceedings of the Royal Society of London, Series A 102, 161-179] for the behaviour of clasts within a viscous material. In addition, some probes also showed short, frequent dip oscillations in spring and autumn, which were interpreted to reflect stick-slip events, similar to lodging; and demonstrated how local conditions can interrupt the predicted rotation pattern. Overall, it is demonstrated that when water pressures were high, decoupling occurred associated with basal sliding and dip oscillations; and when water pressures fell, the ice and sediment were coupled and till deformation occurred. These events happened during summer and autumn. It is this combination of "lodgement" and deformation that builds up both a complex (but predictable) fabric and a

  3. Space Mission to the Moon with a Low Cost Moon Probe Nanosatellite: University Project Feasibility Analysis and Design Concepts

    NASA Astrophysics Data System (ADS)

    Guven, U. G.; Velidi, G. V.; Datta, L. D.

    2014-10-01

    This paper discusses the possibility of launching a 10 kg nanosatellite moon probe with a joint university effort along with industrial partners for a low cost mission to the moon. It will allow for vital experiments to take place.

  4. Space Science

    NASA Image and Video Library

    2000-04-12

    The space vehicle Gravity Probe B (GP-B) is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein’s general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth’s rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. In this photograph, engineer Gary Reynolds is inspecting the inside of the probe neck during probe thermal repairs. GP-B is scheduled for launch in April 2004 and managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Leese, Gravity Probe B, Stanford University)

  5. Initial Biological Damage from Space Radiation: Implications for Development of Biological Countermeasures

    NASA Technical Reports Server (NTRS)

    Cucinotta, Francis A.; Paloski, William H. (Technical Monitor)

    1999-01-01

    Astronauts are exposed to high-energy nuclear particles originating from the galactic cosmic rays, high-energy protons trapped in the Earth's magnetic field or solar particle events, and secondary radiation produced by nuclear reactions. Important differences between conventional radiation including X-rays or gamma-rays, and high-energy nuclei occur at the level of initial damage to DNA and other potential biological target molecules, and to tissues. Such differences include a large fraction of the initial damage from high charge and energy (HZE) nuclear particles manifested as irreparable lesions including small- and large-scale DNA deletions. Also, low dose-rate exposures in space result in a heterogeneous population of damaged cells distinct from energetic photon irradiation of tissue. We present an overview of the initial biological damage and dose and dose-rate effects produced by ionizing radiation using track structure and nuclear reaction models. Implications of the differences in cellular and tissue damage between conventional radiation and space radiation for the development of biological countermeasures are discussed.

  6. Initial Biological Damage from Space Radiation: Implications for Development of Biological Countermeasures

    NASA Technical Reports Server (NTRS)

    Cucinotta, Francis A.; Paloski, William H. (Technical Monitor)

    1999-01-01

    Astronauts are exposed to high-energy nuclear particles originating from the galactic cosmic rays, high-energy protons trapped in the Earth's magnetic field or solar particle events, and secondary radiation produced by nuclear reactions. Important differences between conventional radiation including X-rays or gamma-rays, and high-energy nuclei occur at the level of initial damage to DNA and other potential biological target molecules, and to tissues. Such differences include a large fraction of the initial damage from high charge and energy (HZE) nuclear particles manifested as irreparable lesions including small- and large-scale DNA deletions. Also, low dose-rate exposures in space result in a heterogeneous population of damaged cells distinct from energetic photon irradiation of tissue. We present an overview of the initial biological damage and dose and dose-rate effects produced by ionizing radiation using track structure and nuclear reaction models. Implications of the differences in cellular and tissue damage between conventional radiation and space radiation for the development of biological countermeasures are discussed.

  7. Forces between a rigid probe particle and a liquid interface. III. Extraction of the planar half-space interaction energy E(D).

    PubMed

    Dagastine, Raymond R; Prieve, Dennis C; White, Lee R

    2004-01-01

    The deformation of a liquid drop (radius R0) under the probe particle (radius a) greatly complicates the interpretation by atomic force microscopy. For rigid interfaces, F(DeltaX) can be directly related to the interaction energy E(D) per unit area between planar half-spaces of probe material and drop material across a thickness D of the liquid medium by the Derjaguin approximation, [formula in text], where D(0) is the intersurface separation distance on the line of the centers of the bodies and DeltaX0 is a constant set by the somewhat arbitrary choice of origin for the separation distance DeltaX between the stage on which the drop rests and the lowest point on the probe particle. The problem of absolute intersurface separation distance is common to all surface force measurement techniques. For rigid interfaces, DeltaX0 may be established by bringing the surfaces into close (essentially hard) contact and making measurements in the constant compliance regime. For deformable interfaces, this is not possible and a general method of extracting the absolute separation distance has yet to be devised. In this paper we discuss a general algorithm for extracting E(D+DeltaX0) from F(DeltaX) data. We apply the method to constructed data to investigate the effect of data noise and to a set of real data for a sessile tetradecane droplet in water with an anionic surfactant and a bare silica probe.

  8. HNO/NO Conversion Mechanisms of Cu-Based HNO Probes with Implications for Cu,Zn-SOD

    PubMed Central

    2015-01-01

    HNO has broad biological effects and pharmacological activities. Direct HNO probes for in vivo applications were recently reported, which are CuII-based complexes having fluorescence reporters with reaction to HNO resulting in CuI systems and the release of NO. Their coordination environments are similar to that in Cu,Zn-superoxide dismutase (SOD), which plays a significant role in cellular HNO/NO conversion. However, none of these conversion mechanisms are known. A quantum chemical investigation was performed here to provide structural, energetic, and electronic profiles of HNO/NO conversion pathways via the first CuII-based direct HNO probe. Results not only are consistent with experimental observations but also provide numerous structural and mechanistic details unknown before. Results also suggest the first HNO/NO conversion mechanism for Cu,Zn-SOD, as well as useful guidelines for future design of metal-based HNO probes. These results shall facilitate development of direct HNO probes and studies of HNO/NO conversions via metal complexes and metalloproteins. PMID:24803995

  9. Real-space imaging of molecular structure and chemical bonding by single-molecule inelastic tunneling probe.

    PubMed

    Chiang, Chi-lun; Xu, Chen; Han, Zhumin; Ho, W

    2014-05-23

    The arrangement of atoms and bonds in a molecule influences its physical and chemical properties. The scanning tunneling microscope can provide electronic and vibrational signatures of single molecules. However, these signatures do not relate simply to the molecular structure and bonding. We constructed an inelastic tunneling probe based on the scanning tunneling microscope to sense the local potential energy landscape of an adsorbed molecule with a carbon monoxide (CO)-terminated tip. The skeletal structure and bonding of the molecule are revealed from imaging the spatial variations of a CO vibration as the CO-terminated tip probes the core of the interactions between adjacent atoms. An application of the inelastic tunneling probe reveals the sharing of hydrogen atoms among multiple centers in intramolecular and extramolecular bonding.

  10. Laser-pump/X-ray-probe experiments with electrons ejected from a Cu(111) target: space-charge acceleration.

    PubMed

    Schiwietz, G; Kühn, D; Föhlisch, A; Holldack, K; Kachel, T; Pontius, N

    2016-09-01

    A comprehensive investigation of the emission characteristics for electrons induced by X-rays of a few hundred eV at grazing-incidence angles on an atomically clean Cu(111) sample during laser excitation is presented. Electron energy spectra due to intense infrared laser irradiation are investigated at the BESSY II slicing facility. Furthermore, the influence of the corresponding high degree of target excitation (high peak current of photoemission) on the properties of Auger and photoelectrons liberated by a probe X-ray beam is investigated in time-resolved pump and probe measurements. Strong electron energy shifts have been found and assigned to space-charge acceleration. The variation of the shift with laser power and electron energy is investigated and discussed on the basis of experimental as well as new theoretical results.

  11. A model of heat transfer in sapwood and implications for sap flux density measurements using thermal dissipation probes.

    PubMed

    Wullschleger, Stan D; Childs, Kenneth W; King, Anthony W; Hanson, Paul J

    2011-06-01

    A variety of thermal approaches are used to estimate sap flux density in stems of woody plants. Models have proved valuable tools for interpreting the behavior of heat pulse, heat balance and heat field deformation techniques, but have seldom been used to describe heat transfer dynamics for the heat dissipation method. Therefore, to better understand the behavior of heat dissipation probes, a model was developed that takes into account the thermal properties of wood, the physical dimensions and thermal characteristics of the probes, and the conductive and convective heat transfer that occurs due to water flow in the sapwood. Probes were simulated as aluminum tubes 20 mm in length and 2 mm in diameter, whereas sapwood, heartwood and bark each had a density and water fraction that determined their thermal properties. Base simulations assumed a constant sap flux density with sapwood depth and no wounding or physical disruption of xylem beyond the 2 mm diameter hole drilled for probe installation. Simulations across a range of sap flux densities showed that the dimensionless quantity k [defined as (ΔT(m) -ΔT)/ΔT, where ΔT(m) is the temperature differential (ΔT) between the heated and unheated probe under zero-flow conditions] was dependent on the thermal conductivity of the sapwood. The relationship between sap flux density and k was also sensitive to radial gradients in sap flux density and to xylem disruption near the probe. Monte Carlo analysis in which 1000 simulations were conducted while simultaneously varying thermal conductivity and wound diameter revealed that sap flux density and k showed considerable departure from the original calibration equation used with this technique. The departure was greatest for variation in sap flux density typical of ring-porous species. Depending on the specific combination of thermal conductivity and wound diameter, use of the original calibration equation resulted in an 81% under- to 48% overestimation of sap flux density

  12. A model of heat transfer in sapwood and implications for sap flux density measurements using thermal dissipation probes

    SciTech Connect

    Wullschleger, Stan D; Childs, Kenneth W; King, Anthony Wayne; Hanson, Paul J

    2011-01-01

    A variety of thermal approaches are used to estimate sap flux density in stems of woody plants. Models have proven valuable tools for interpreting the behavior of heat pulse, heat balance, and heat field deformation techniques, but have seldom been used to describe heat transfer dynamics for the heat dissipation method. Therefore, to better understand the behavior of heat dissipation probes, a model was developed that takes into account the thermal properties of wood, the physical dimensions and thermal characteristics of the probes, and the conductive and convective heat transfer that occurs due to water flow in the sapwood. Probes were simulated as aluminum tubes 20 mm in length and 2 mm in diameter, whereas sapwood, heartwood, and bark each had a density and water fraction that determined their thermal properties. Base simulations assumed a constant sap flux density with sapwood depth and no wounding or physical disruption of xylem beyond the 2 mm diameter hole drilled for probe installation. Simulations across a range of sap flux densities showed that the dimensionless quantity k defined as ( Tm T)/ T where Tm is the temperature differential ( T) between the heated and unheated probe under zero flow conditions was dependent on the thermal conductivity of the sapwood. The relationship between sap flux density and k was also sensitive to radial gradients in sap flux density and to xylem disruption near the probe. Monte Carlo analysis in which 1000 simulations were conducted while simultaneously varying thermal conductivity and wound diameter revealed that sap flux density and k showed considerable departure from the original calibration equation used with this technique. The departure was greatest for abrupt patterns of radial variation typical of ring-porous species. Depending on the specific combination of thermal conductivity and wound diameter, use of the original calibration equation resulted in an 81% under- to 48% over-estimation of sap flux density at

  13. Interaction of solar wind with Mercury and its magnetic field. [as observed by Mariner 10 space probe

    NASA Technical Reports Server (NTRS)

    Ness, N. F.; Behannon, K. W.; Lepping, R. P.; Whang, Y. C.

    1976-01-01

    A brief review is presented of magnetic field and solar wind electron observations by Mariner 10 spacecraft. The intrinsic magnetic field of the planet Mercury and the implications of such a field for the planetary interior are also discussed.

  14. Mechanism of Carbamate Inactivation of FAAH: Implications for the Design of Covalent Inhibitors and In Vivo Functional Probes for Enzymes

    PubMed Central

    Alexander, Jessica P.; Cravatt, Benjamin F.

    2006-01-01

    Summary Fatty acid amide hydrolase (FAAH) regulates a large class of signaling lipids, including the endocannabinoid anandamide. Carbamate inhibitors of FAAH display analgesic and anxiolytic properties in rodents. However, the mechanism by which carbamates inhibit FAAH remains obscure. Here, we provide biochemical evidence that carbamates covalently modify the active site of FAAH by adopting an orientation opposite of that originally predicted from modeling. Based on these results, a series of carbamates was designed that display enhanced potency. One agent was converted into a “click chemistry” probe to comprehensively evaluate the proteome reactivity of FAAH-directed carbamates in vivo. These inhibitors were selective for FAAH in the nervous system, but they reacted with several enzymes in peripheral tissues. The experimental strategy described herein can be used to create in vivo probes for any enzyme susceptible to covalent inhibition. PMID:16298297

  15. In Vivo Tumor Secretion Probing Via Ultrafiltration and Tissue Chamber: Implication for Anti-Cancer Drugs Targeting Secretome

    PubMed Central

    Huang, Chun-Ming; Nakatsuji, Teruaki; Liu, Yu-Tseung; Shi, Yang

    2009-01-01

    Tumor secreted proteins/peptides (tumor secretome) act as mediators of tumor-host communication in the tumor microenvironment. Therefore, development of anti-cancer drugs targeting secretome may effectively control tumor progression. Novel techniques including a capillary ultrafiltration (CUF) probe and a dermis-based cell-trapped system (DBCTS) linked to a tissue chamber were utilized to sample in vivo secretome from tumor masses and microenvironments. The CUF probe and tissue chamber were evaluated in the context of in vivo secretome sampling. Both techniques have been successfully integrated with mass spectrometry for secretome identification. A secretome containing multiple proteins and peptides can be analyzed by NanoLC-LTQ mass spectrometry, which is specially suited to identifying proteins in a complex mixture. In the future, the establishment of comprehensive proteomes of various host and tumor cells, as well as plasma will help in distinguishing the cellular sources of secretome. Many detection methods have been patented regarding probes and peptide used for identification of tumors. PMID:18289123

  16. Consolidated fuel reprossing program: The implications of force reflection for teleoperation in space

    NASA Technical Reports Server (NTRS)

    Draper, John V.; Herndon, Joseph N.; Moore, Wendy E.

    1987-01-01

    Previous research on teleoperator force feedback is reviewed and results of a testing program which assessed the impact of force reflection on teleoperator task performance are reported. Force relection is a type of force feedback in which the forces acting on the remote portion of the teleoperator are displayed to the operator by back-driving the master controller. The testing program compared three force reflection levels: 4 to 1 (four units of force on the slave produce one unit of force at the master controller), 1 to 1, and infinity to 1 (no force reflection). Time required to complete tasks, rate of occurrence of errors, the maximum force applied to tasks components, and variability in forces applied to components during completion of representative remote handling tasks were used as dependent variables. Operators exhibited lower error rates, lower peak forces, and more consistent application of forces using force relection than they did without it. These data support the hypothesis that force reflection provides useful information for teleoperator users. The earlier literature and the results of the experiment are discussed in terms of their implications for space based teleoperator systems. The discussion described the impact of force reflection on task completion performance and task strategies, as suggested by the literature. It is important to understand the trade-offs involved in using telerobotic systems with and without force reflection.

  17. Scientific Implications of the Modified Observing Strategy of the Fermi Gamma-ray Space Telescope

    NASA Astrophysics Data System (ADS)

    McEnery, Julie E.; Fermi-LAT Collaboration; Fermi-GBM Team

    2014-01-01

    Near the end of 2013 the Fermi Gamma-ray Space Telescope (Fermi) mission plans to change to a modified observing strategy designed to favor the Galactic center while maintaining full sky-survey capabilities. This change would have important implications for the science of the Fermi Large Area Telescope (Fermi-LAT). In particular, this change will 1) substantially increase the Fermi-LAT sensitivity to young pulsars in the inner Galaxy, 2) provide simultaneous observations of the Galactic center with a suite of other instruments that have extended observing campaigns of the expected disruption of the G2 gas cloud complex (see https://wiki.mpe.mpg.de/gascloud/ProposalList) , 3) double the rate of improvement of statistical power for of searches for spectral lines from the Galactic center. In this contribution we discuss these topics. We also investigate ways in which the modified observing strategy can induce systematic biases, and discuss how those biases can be studied and mitigated with studies of control samples of LAT data.

  18. Lower limb kinematics during treadmill walking after space flight: implications for gaze stabilization

    NASA Technical Reports Server (NTRS)

    McDonald, P. V.; Basdogan, C.; Bloomberg, J. J.; Layne, C. S.

    1996-01-01

    We examined the lower limb joint kinematics observed during pre- and postflight treadmill walking performed by seven subjects from three Space Shuttle flights flown between March 1992 and February 1994. Basic temporal characteristics of the gait patterns, such as stride time and duty cycle, showed no significant changes after flight. Evaluation of phaseplane variability across the gait cycle suggests that postflight treadmill walking is more variable than preflight, but the response throughout the course of a cycle is joint dependent and, furthermore, the changes are subject dependent. However, analysis of the phaseplane variability at the specific locomotor events of heel strike and toe off indicated statistically significant postflight increases in knee variability at the moment of heel strike and significantly higher postflight hip joint variability at the moment of toe off. Nevertheless, the observation of component-specific variability was not sufficient to cause a change in the overall lower limb joint system stability, since there was no significant change in an index used to evaluate this at both toe off and heel strike. The implications of the observed lower limb kinematics for head and gaze control during locomotion are discussed in light of a hypothesized change in the energy attenuation capacity of the musculoskeletal system in adapting to weightlessness.

  19. Certain forms of matrix metalloproteinase-9 accumulate in the extracellular space after microdialysis probe implantation and middle cerebral artery occlusion/reperfusion.

    PubMed

    Planas, Anna M; Justicia, Carles; Solé, Sònia; Friguls, Bibiana; Cervera, Alvaro; Adell, Albert; Chamorro, Angel

    2002-08-01

    Matrix metalloproteinases (MMPs) are activated in focal cerebral ischemia. The activation of MMP-9 is involved in blood-brain barrier breakdown and tissue remodeling. The MMPs are released to the extracellular space, but the form and fate of secreted enzymes in brain are unknown. Using microdialysis in vivo, the authors studied whether ischemia-induced MMP-9 in brain tissue was related to free MMP-9 in the extracellular fluid. A microdialysis probe was placed into the right striatum and microdialysis was initiated 24 hours later in controls (n = 7). One hour prior to microdialysis, a group of rats (n = 7) was subjected to 1-hour occlusion of the right middle cerebral artery, followed by reperfusion. Dialysates were collected at discrete time points up to 24 hours, and subjected to zymography and Western blot analysis. The MMP-9 was released after ischemia and accumulated in the extracellular space at 24 hours (P < 0.05). Free MMP-9 forms include mainly the 95-kd proform, and, to a lesser extent, dimers and cleaved active forms (70 kd), but not the 88-kd form found in tissue. Probe implantation and microdialysis increased free MMP-9 in the dialysate. This increase was concomitant with neutrophil infiltration after the mechanical lesion, as myeloperoxidase was found by means of Western blot analysis in the brain hemisphere subjected to microdialysis (P < 0.005), and immunohistochemistry revealed the presence of myeloperoxidase stain surrounding the site of probe implantation. The results suggest that certain forms of MMP-9 are released and accumulate in the extracellular space after brain injury, and that vascular alterations and neutrophil recruitment elicit MMP-9 activation in the brain after focal ischemia and trauma.

  20. KENNEDY SPACE CENTER, FLA. - This seal illustrates the mission of the Gravity Probe B spacecraft and the organizations who developed the experiment: Stanford University, NASA’s Marshall Space Flight Center and Lockheed Martin. The Gravity Probe B mission will test the theory of curved spacetime and "frame-dragging," depicted graphically in the lower half, that was developed by Einstein and other scientists. Above the graphic is a drawing of GP-B circling the Earth.

    NASA Image and Video Library

    2003-10-30

    KENNEDY SPACE CENTER, FLA. - This seal illustrates the mission of the Gravity Probe B spacecraft and the organizations who developed the experiment: Stanford University, NASA’s Marshall Space Flight Center and Lockheed Martin. The Gravity Probe B mission will test the theory of curved spacetime and "frame-dragging," depicted graphically in the lower half, that was developed by Einstein and other scientists. Above the graphic is a drawing of GP-B circling the Earth.

  1. Hematoma in Retzius' space following US-guided prostate biopsy: evidence of the diagnostic accuracy using transrectal end-fire probe in the anterior prostate gland.

    PubMed

    Dell'atti, Lucio

    2014-03-01

    We report a rare case of hematoma in Retzius' space in a 62-year-old man who underwent transrectal prostate biopsy using an endocavitary, end-fire, convex probe. Clinical symptoms resolved spontaneously after catheter placement and appropriate antibiotic therapy. Transrectal ultrasound 1 month later showed partial resolution of the hematoma. Based on the analysis of this unusual complication, we demonstrate the effectiveness of transrectal biopsy as compared to transperineal biopsy in detecting cancer of the anterior prostate. We have also analyzed the various factors that may be the reason why core biopsy harvested in this "hidden" area may be inadequate.

  2. Data analysis to separate particles of different speed regimes and charges. [lunar ejecta and meteorite experiment and pioneer space probe data

    NASA Technical Reports Server (NTRS)

    Wolf, H.

    1977-01-01

    Although the instruments on the lunar ejecta and meteorite experiment (LEAM) and the Pioneer 8 and 9 space probes were essentially similar, a comparison of their results indicates that different sets of particles caused the different responses. On Pioneer, the events were caused by the impact of cosmic dust, the so-called beta particles expelled from the vicinity of the sun by solar radiation pressure, augmented by extremely high energy but definitely identifiable interstellar grains. On the moon, the events were due to the impact of slowly moving, highly charged lunar dust being propelled electrostatically across the terminator. Both theoretical analysis and experimental testing confirming these conclusions are discussed.

  3. Rotary probe traversing mechanism

    NASA Astrophysics Data System (ADS)

    Hokenson, Gustave J.

    1985-04-01

    A simple mechanical device is presented which allows a probe to scan a plane in space without translating the probe support. The mechanism relies on the rotation of two shafts, one of which rotates the probe through space and the other controls the probe offset from the axis of rotation. The characteristic width of the area swept out is four times the characteristic width of the device. A simple ratcheting gear allows adjacent planes to be scanned for the purpose of obtaining gradients. Computerized control of the shafts rotations also allows noncircular domains to be scanned.

  4. Measuring the Thickness and Potential Profiles of the Space-Charge Layer at Organic/Organic Interfaces under Illumination and in the Dark by Scanning Kelvin Probe Microscopy.

    PubMed

    Rojas, Geoffrey A; Wu, Yanfei; Haugstad, Greg; Frisbie, C Daniel

    2016-03-09

    Scanning Kelvin probe microscopy was used to measure band-bending at the model donor/acceptor heterojunction poly(3-hexylthiophene) (P3HT)/fullerene (C60). Specifically, we measured the variation in the surface potential of C60 films with increasing thicknesses grown on P3HT to produce a surface potential profile normal to the substrate both in the dark and under illumination. The results confirm a space-charge carrier region with a thickness of 10 nm, consistent with previous observations. We discuss the possibility that the domain size in bulk heterojunction organic solar cells, which is comparable to the space-charge layer thickness, is actually partly responsible for less than expected electron/hole recombination rates.

  5. Prototropism of 1-hydroxypyrene in liposome suspensions: implications towards fluorescence probing of lipid bilayers in alkaline medium.

    PubMed

    Subuddhi, Usharani; Mishra, Ashok K

    2006-03-01

    The partitioning efficiency of neutral and anionic prototropic forms of 1-hydroxypyrene in liposome suspensions has been studied. The high partition coefficient value of 1-hydroxypyrene indicates an easy incorporation of the molecule into the lipid bilayer. Detailed pH studies indicate that only the neutral form of 1-hydroxypyrene partitions into the membrane and appreciable spectral changes are observed in the pH range of 9.0-11.5 in Tris-NaOH buffer. However, at pH 11 the spectral changes are maximum. The possibility of using 1-hydroxypyrene as a fluorescent molecular probe for lipid bilayer membranes in alkaline media has been examined, by employing fluorescence intensity and fluorescence anisotropy as probe parameters. The neutral form fluorescence intensity as well as fluorescence anisotropy is sensitive to the changes in the membrane properties and is capable of sensing the phase-transition. This is also capable of monitoring the changes in the membrane due to incorporation of cholesterol and the ethanol-induced interdigitation. The time resolved fluorescence data and the quenching experiments show that 1-hydroxypyrene occupies the water inaccessible interior of the liposome. The high anisotropy value of 1-hydroxypyrene in liposome suggests that it resides in a considerably rigid environment and is very sensitive to the temperature-induced changes in the liposome.

  6. Nitroxidative chemistry interferes with fluorescent probe chemistry: implications for nitric oxide detection using 2,3-diaminonaphthalene.

    PubMed

    Hu, Teh-Min; Chiu, Shih-Jiuan; Hsu, Yu-Ming

    2014-08-22

    Simultaneous production of nitric oxide (NO) and superoxide generates peroxynitrite and causes nitroxidative stress. The fluorometric method for NO detection is based on the formation of a fluorescent product from the reaction of a nonfluorescent probe molecule with NO-derived nitrosating species. Here, we present an example of how nitroxidative chemistry could interact with fluorescent probe chemistry. 2,3-Naphthotriazole (NAT) is the NO-derived fluorescent product of 2,3-diaminonaphthalene (DAN), a commonly used NO-detecting molecule. We show that NO/superoxide cogeneration, and particularly peroxynitrite, mediates the chemical decomposition of NAT. Moreover, the extent of NAT decomposition depends on the relative fluxes of NO and superoxide; the maximum effect being reached at almost equivalent generation rates for both radicals. The rate constant for the reaction of NAT with peroxynitrite was determined to be 2.2×10(3)M(-1)s(-1). Further, various peroxynitrite scavengers were shown to effectively inhibit NO/superoxide- and peroxynitrite-mediated decomposition of NAT. Taken together, the present study suggests that the interference of a fluorometric NO assay can be originated from the interaction between the final fluorescent product and the formed reactive nitrogen and oxygen species.

  7. Comparison of Metal-Backed Free-Space and Open-Ended Coaxial Probe Techniques for the Dielectric Characterization of Aeronautical Composites.

    PubMed

    López-Rodríguez, Patricia; Escot-Bocanegra, David; Poyatos-Martínez, David; Weinmann, Frank

    2016-06-24

    The trend in the last few decades is that current unmanned aerial vehicles are completely made of composite materials rather than metallic, such as carbon-fiber or fiberglass composites. From the electromagnetic point of view, this fact forces engineers and scientists to assess how these materials may affect their radar response or their electronics in terms of electromagnetic compatibility. In order to evaluate this, electromagnetic characterization of different composite materials has become a need. Several techniques exist to perform this characterization, all of them based on the utilization of different sensors for measuring different parameters. In this paper, an implementation of the metal-backed free-space technique, based on the employment of antenna probes, is utilized for the characterization of composite materials that belong to an actual drone. Their extracted properties are compared with those given by a commercial solution, an open-ended coaxial probe (OECP). The discrepancies found between both techniques along with a further evaluation of the methodologies, including measurements with a split-cavity resonator, conclude that the implemented free-space technique provides more reliable results for this kind of composites than the OECP technique.

  8. Comparison of Metal-Backed Free-Space and Open-Ended Coaxial Probe Techniques for the Dielectric Characterization of Aeronautical Composites †

    PubMed Central

    López-Rodríguez, Patricia; Escot-Bocanegra, David; Poyatos-Martínez, David; Weinmann, Frank

    2016-01-01

    The trend in the last few decades is that current unmanned aerial vehicles are completely made of composite materials rather than metallic, such as carbon-fiber or fiberglass composites. From the electromagnetic point of view, this fact forces engineers and scientists to assess how these materials may affect their radar response or their electronics in terms of electromagnetic compatibility. In order to evaluate this, electromagnetic characterization of different composite materials has become a need. Several techniques exist to perform this characterization, all of them based on the utilization of different sensors for measuring different parameters. In this paper, an implementation of the metal-backed free-space technique, based on the employment of antenna probes, is utilized for the characterization of composite materials that belong to an actual drone. Their extracted properties are compared with those given by a commercial solution, an open-ended coaxial probe (OECP). The discrepancies found between both techniques along with a further evaluation of the methodologies, including measurements with a split-cavity resonator, conclude that the implemented free-space technique provides more reliable results for this kind of composites than the OECP technique. PMID:27347966

  9. Studying Geoeffective Interplanetary Coronal Mass Ejections Between the Sun and Earth: Space Weather Implications of Solar Mass Ejection Imager Observations

    DTIC Science & Technology

    2009-05-14

    during the Mav 12th, 1997 ICME, /. Ahnos. Sol. Terr. Phys., 66, 1295-1309. Billings, D. E. (1966), A Guide to the Solar Corona , Academic, San Diego...SUBTITLE Studying geoeffective interplanetary coronal mass ejections Between the Sun and Earth: Space weather implications of Solar Mass Ejection...DISTRIBUTION . „ . ru^en.1 nomicmcni Approved for Public Release; Distribution Unlimited. *Boston College, Chestnut Hill, MA, **AFRL, National Solar Ob

  10. Using (18)O/(16)O exchange to probe an equilibrium space-charge layer at the surface of a crystalline oxide: method and application.

    PubMed

    De Souza, Roger A; Martin, Manfred

    2008-05-07

    The use of an (18)O/(16)O exchange experiment as a means for probing surface space-charge layers in oxides is examined theoretically and experimentally. On the basis of a theoretical treatment, isotope penetration profiles are calculated for (18)O/(16)O exchange across a gas-solid interface and subsequent diffusion of the labelled isotope through an equilibrium space-charge layer depleted of mobile oxygen vacancies and into a homogeneous bulk phase. Profiles calculated for a range of conditions all have a characteristic shape: a sharp drop in isotope fraction close to the surface followed by a normal bulk diffusion profile. Experimental (18)O profiles in an exchanged (001) oriented single crystal of Fe-doped SrTiO(3) were measured by time-of-flight secondary ion mass spectrometry (ToF-SIMS). By extracting the space-charge potential from such profiles, we demonstrate that this method allows the spatially resolved characterization of space-charge layers at the surfaces of crystalline oxides under thermodynamically well-defined conditions.

  11. Gravity Probe B Assembled

    NASA Technical Reports Server (NTRS)

    2000-01-01

    In this photo, the Gravity Probe B (GP-B) space vehicle is being assembled at the Sunnyvale, California location of the Lockheed Martin Corporation. The GP-B is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Underwood, Lockheed Martin Corporation).

  12. Probing the Solar System

    ERIC Educational Resources Information Center

    Wilkinson, John

    2013-01-01

    Humans have always had the vision to one day live on other planets. This vision existed even before the first person was put into orbit. Since the early space missions of putting humans into orbit around Earth, many advances have been made in space technology. We have now sent many space probes deep into the Solar system to explore the planets and…

  13. Probing the Solar System

    ERIC Educational Resources Information Center

    Wilkinson, John

    2013-01-01

    Humans have always had the vision to one day live on other planets. This vision existed even before the first person was put into orbit. Since the early space missions of putting humans into orbit around Earth, many advances have been made in space technology. We have now sent many space probes deep into the Solar system to explore the planets and…

  14. Radiation Effects on Emerging Technologies: Implications of Space Weather Risk Management

    NASA Technical Reports Server (NTRS)

    LaBel, Kenneth A.; Barth, Janet L.

    2000-01-01

    As NASA and its space partners endeavor to develop a network of satellites capable of supporting humankind's needs for advanced space weather prediction and understanding, one of the key challenges is to design a space system to operate in the natural space radiation environment In this paper, we present a description of the natural space radiation environment, the effects of interest to electronic or photonic systems, and a sample of emerging technologies and their specific issues. We conclude with a discussion of operations in the space radiation hazard and considerations for risk management.

  15. Electrical resistivity probes

    DOEpatents

    Lee, Ki Ha; Becker, Alex; Faybishenko, Boris A.; Solbau, Ray D.

    2003-10-21

    A miniaturized electrical resistivity (ER) probe based on a known current-voltage (I-V) electrode structure, the Wenner array, is designed for local (point) measurement. A pair of voltage measuring electrodes are positioned between a pair of current carrying electrodes. The electrodes are typically about 1 cm long, separated by 1 cm, so the probe is only about 1 inch long. The electrodes are mounted to a rigid tube with electrical wires in the tube and a sand bag may be placed around the electrodes to protect the electrodes. The probes can be positioned in a borehole or on the surface. The electrodes make contact with the surrounding medium. In a dual mode system, individual probes of a plurality of spaced probes can be used to measure local resistance, i.e. point measurements, but the system can select different probes to make interval measurements between probes and between boreholes.

  16. Measuring planetary field parameters by scattered cubes from the Husar-5 rover: educational space probe construction for a field work mission with great number of 5 cm sized sensorcube units launched from the rover.

    NASA Astrophysics Data System (ADS)

    Lang, A.; Kocsis, A.; Gats, J.

    2015-10-01

    The Hunveyor-Husar project tries to keep step with the main trends in the space research, in our recent case with the so called MSSM (Micro Sized Space- Mothership) and NPSDR (Nano, Pico Space Devices and Robots). [1]Of course, we do not want to scatter the smaller probe-cubes from a mothership, but from the Husar rover, and to do it on the planetary surface after landing.

  17. Space Lexicalized: Its Linguistic Impacts in English and Its Implications for EFL Learning

    ERIC Educational Resources Information Center

    Kadarisman, A. Effendi

    2010-01-01

    Our sense of space is part of our experiential universals. However, the incorporation of space into words differs across languages. This paper argues that "space" is lexicalized in English but not in Indonesian. English encodes the sense of location and direction into "adverbial particles," producing language-specific…

  18. Space Lexicalized: Its Linguistic Impacts in English and Its Implications for EFL Learning

    ERIC Educational Resources Information Center

    Kadarisman, A. Effendi

    2010-01-01

    Our sense of space is part of our experiential universals. However, the incorporation of space into words differs across languages. This paper argues that "space" is lexicalized in English but not in Indonesian. English encodes the sense of location and direction into "adverbial particles," producing language-specific…

  19. Role, Impacts and Implications of Dedicated Aboriginal Student Space at a Canadian University

    ERIC Educational Resources Information Center

    Smith, Natasha L.; Varghese, Jeji

    2016-01-01

    This article draws on a case study of the University of Guelph's Aboriginal Resource Centre (ARC) to identify the role that dedicated spaces have in the lives of Aboriginal students. Three roles that were identified include how these spaces build a sense of community, foster and enhance Aboriginal identity, and provide a safe space for Aboriginal…

  20. Role, Impacts and Implications of Dedicated Aboriginal Student Space at a Canadian University

    ERIC Educational Resources Information Center

    Smith, Natasha L.; Varghese, Jeji

    2016-01-01

    This article draws on a case study of the University of Guelph's Aboriginal Resource Centre (ARC) to identify the role that dedicated spaces have in the lives of Aboriginal students. Three roles that were identified include how these spaces build a sense of community, foster and enhance Aboriginal identity, and provide a safe space for Aboriginal…

  1. Observations of the Variable Coronal Solar Wind, and its Implications for Solar Probe Plus and Solar Orbiter

    NASA Astrophysics Data System (ADS)

    Jackson, B. V.; Yu, H. S.; Hick, P. P.; Buffington, A.

    2016-12-01

    Solar wind observations from Ulysses show polar solar regions at solar minimum to be uniform and non-structured. However, when analyzing LASCO C2 and STEREO SECCHI COR2 coronagraph images, and using UCSD-developed correlation-tracking techniques, we find the observed solar wind outflow during these periods is not a static well-ordered motion, but instead has highly-variable speed structures. These high-speed polar structures are associated with slightly brighter (and also patchy) coronal structures. When the high-speed patches are averaged with the slower surrounding corona, the solar wind acceleration with solar distance is observed consistently across the polar coronal hole regions. This change in speed with distance is also consistent with the outward flow speed observed in polar regions determined from mass flux considerations and known coronagraph polarization brightness. From this we conclude that Solar Probe Plus and Solar Orbiter will not only be able to measure these structures in situ as variable wind, but they may also be able to determine the key parameters associated with these structures and how these parameters (abundances and magnetic fields) are related to the solar wind acceleration that is observed remotely in coronagraph observations.

  2. Asymmetry of configuration space induced by unequal crossover: implications for a mathematical theory of evolutionary innovation.

    PubMed

    Shpak, M; Wagner, G P

    2000-01-01

    Evolution can be regarded as the exploration of genetic or morphological state space by populations. In traditional models of population and quantitative genetics, the state space can be formally represented as a configuration space with clearly defined concepts of neighborhood and distance, defined by the action of variational operators such as mutation and/or recombination. In this paper, we describe a process where no genetic configuration space closure (and hence, no non-arbitrary notion of distance and neighborhood) exists. The process is gene duplication by means of unequal crossover, which we regard as an example of an "innovation" process that changes the state space of the system rather than exploring a closed state space. We assert that such processes are qualitatively distinct from representations of the adaptation process, which occur on regular configuration spaces.

  3. Science with the space-based interferometer eLISA. III: probing the expansion of the universe using gravitational wave standard sirens

    NASA Astrophysics Data System (ADS)

    Tamanini, Nicola; Caprini, Chiara; Barausse, Enrico; Sesana, Alberto; Klein, Antoine; Petiteau, Antoine

    2016-04-01

    We investigate the capability of various configurations of the space interferometer eLISA to probe the late-time background expansion of the universe using gravitational wave standard sirens. We simulate catalogues of standard sirens composed by massive black hole binaries whose gravitational radiation is detectable by eLISA, and which are likely to produce an electromagnetic counterpart observable by future surveys. The main issue for the identification of a counterpart resides in the capability of obtaining an accurate enough sky localisation with eLISA. This seriously challenges the capability of four-link (2 arm) configurations to successfully constrain the cosmological parameters. Conversely, six-link (3 arm) configurations have the potential to provide a test of the expansion of the universe up to z ~ 8 which is complementary to other cosmological probes based on electromagnetic observations only. In particular, in the most favourable scenarios, they can provide a significant constraint on H0 at the level of 0.5%. Furthermore, (ΩM, ΩΛ) can be constrained to a level competitive with present SNIa results. On the other hand, the lack of massive black hole binary standard sirens at low redshift allows to constrain dark energy only at the level of few percent.

  4. Science with the space-based interferometer eLISA. III: probing the expansion of the universe using gravitational wave standard sirens

    SciTech Connect

    Tamanini, Nicola; Caprini, Chiara; Barausse, Enrico; Sesana, Alberto; Klein, Antoine; Petiteau, Antoine E-mail: chiara.caprini@cea.fr E-mail: asesana@star.sr.bham.ac.uk E-mail: antoine.petiteau@apc.univ-paris7.fr

    2016-04-01

    We investigate the capability of various configurations of the space interferometer eLISA to probe the late-time background expansion of the universe using gravitational wave standard sirens. We simulate catalogues of standard sirens composed by massive black hole binaries whose gravitational radiation is detectable by eLISA, and which are likely to produce an electromagnetic counterpart observable by future surveys. The main issue for the identification of a counterpart resides in the capability of obtaining an accurate enough sky localisation with eLISA. This seriously challenges the capability of four-link (2 arm) configurations to successfully constrain the cosmological parameters. Conversely, six-link (3 arm) configurations have the potential to provide a test of the expansion of the universe up to z ∼ 8 which is complementary to other cosmological probes based on electromagnetic observations only. In particular, in the most favourable scenarios, they can provide a significant constraint on H{sub 0} at the level of 0.5%. Furthermore, (Ω{sub M}, Ω{sub Λ}) can be constrained to a level competitive with present SNIa results. On the other hand, the lack of massive black hole binary standard sirens at low redshift allows to constrain dark energy only at the level of few percent.

  5. Detection of GRB 060927 at zeta = 5.47: Implications for the Use of Gamma-Ray Bursts as Probes of the End of the Dark Ages

    NASA Technical Reports Server (NTRS)

    Ruiz-Velasco, A. E.; Swan, H.; Troja, E.; Malesani, D.; Fynbo, J. P. U.; Sterling, R. L. C.; Xu, D.; Aharonian, F.; Akerlof, C.; Andersen, M. I.; hide

    2007-01-01

    We report on follow-up observations of the gamma-ray burst GRB 060927 using the robotic ROTSE-IIIa telescope and a suite of larger aperture groundbased telescopes. An optical afterglow was detected 20 s after the burst, the earliest rest-frame detection of optical emission from any GRB. Spectroscopy performed with the VLT about 13 hours after the trigger shows a continuum break at lambda approx. equals 8070 A, produced by neutral hydrogen absorption at zeta = 5.6. We also detect an absorption line at 8158 A which we interpret as Si II lambda 1260 at zeta = 5.467. Hence, GRB 060927 is the second most distant GRB with a spectroscopically measured redshift. The shape of the red wing of the spectral break can be fitted by a damped Ly(alpha) profile with a column density with log(N(sub HI)/sq cm) = 22.50 +/- 0.15. We discuss the implications of this work for the use of GRBs as probes of the end of the dark ages and draw three main conclusions: i) GRB afterglows originating from zeta greater than or approx. equal to 6 should be relatively easy to detect from the ground, but rapid near-infrared monitoring is necessary to ensure that they are found; ii) The presence of large H I column densities in some GRBs host galaxies at zeta > 5 makes the use of GRBs to probe the reionization epoch via spectroscopy of the red damping wing challenging; iii) GRBs appear crucial to locate typical star-forming galaxies at zeta > 5 and therefore the type of galaxies responsible for the reionization of the universe.

  6. Detection of GRB 060927 at z = 5.47: Implications for the Use of Gamma-Ray Bursts as Probes of the End of the Dark Ages

    NASA Astrophysics Data System (ADS)

    Ruiz-Velasco, A. E.; Swan, H.; Troja, E.; Malesani, D.; Fynbo, J. P. U.; Starling, R. L. C.; Xu, D.; Aharonian, F.; Akerlof, C.; Andersen, M. I.; Ashley, M. C. B.; Barthelmy, S. D.; Bersier, D.; Castro Cerón, J. M.; Castro-Tirado, A. J.; Gehrels, N.; Göǧüş, E.; Gorosabel, J.; Guidorzi, C.; Güver, T.; Hjorth, J.; Horns, D.; Huang, K. Y.; Jakobsson, P.; Jensen, B. L.; Kızıloǧlu, Ü.; Kouveliotou, C.; Krimm, H. A.; Ledoux, C.; Levan, A. J.; Marsh, T.; McKay, T.; Melandri, A.; Milvang-Jensen, B.; Mundell, C. G.; O'Brien, P. T.; Özel, M.; Phillips, A.; Quimby, R.; Rowell, G.; Rujopakarn, W.; Rykoff, E. S.; Schaefer, B. E.; Sollerman, J.; Tanvir, N. R.; Thöne, C. C.; Urata, Y.; Vestrand, W. T.; Vreeswijk, P. M.; Watson, D.; Wheeler, J. C.; Wijers, R. A. M. J.; Wren, J.; Yost, S. A.; Yuan, F.; Zhai, M.; Zheng, W. K.

    2007-11-01

    We report on follow-up observations of the gamma-ray burst GRB 060927 using the robotic ROTSE-IIIa telescope and a suite of larger aperture ground-based telescopes. An optical afterglow was detected 20 s after the burst, the earliest rest-frame detection of optical emission from any GRB. Spectroscopy performed with the VLT about 13 hr after the trigger shows a continuum break at λ~8070 Å, produced by neutral hydrogen absorption at z~5.6. We also detect an absorption line at 8158 Å, which we interpret as Si II λ1260 at z=5.467. Hence, GRB 060927 is the second most distant GRB with a spectroscopically measured redshift. The shape of the red wing of the spectral break can be fitted by a damped Lyα profile with a column density with log(NH/cm-2)=22.50+/-0.15. We discuss the implications of this work for the use of GRBs as probes of the end of the dark ages and draw three main conclusions: (1) GRB afterglows originating from z>~6 should be relatively easy to detect from the ground, but rapid near-infrared monitoring is necessary to ensure that they are found; (2) the presence of large H I column densities in some GRB host galaxies at z>5 makes the use of GRBs to probe the reionization epoch via spectroscopy of the red damping wing challenging; and (3) GRBs appear crucial to locate typical star-forming galaxies at z>5, and therefore the type of galaxies responsible for the reionization of the universe. Partly based on observations carried out with the ESO telescopes under programs 077.D-0661, 077.A-0667, 078.D-0416, and the large program 177.A-f0591.

  7. Environmental effects on phosphoryl group bonding probed by vibrational spectroscopy: implications for understanding phosphoryl transfer and enzymatic catalysis.

    PubMed

    Cheng, Hu; Nikolic-Hughes, Ivana; Wang, Jianghua H; Deng, Hua; O'Brien, Patrick J; Wu, Li; Zhang, Zhong-Yin; Herschlag, Daniel; Callender, Robert

    2002-09-25

    We have used vibrational spectroscopy to study bonding in monosubstituted dianionic phosphates, both to learn more about basic properties intrinsic to this important class of biological substrates and to assess the ability of vibrational spectroscopy to provide a "sensor" or probe of the local environment experienced by the phosphoryl group. We examined the bonding properties of the phosphoryl group via vibrational spectroscopy for a series of compounds in which the phosphoryl substituent was varied systematically and extensively. A broad linear correlation of the bridging P-O(R) bond length and the pK(a) of the substituent alcohol was observed. The results indicate that the P-O(R) bond changes by only approximately 0.04 A with alcohol substituents that vary in pK(a) by approximately 12 units, suggesting that phosphoryl group bonding responds in a subtle but regular manner to changes in the local environment. We also determined the effect on the phosphoryl bonding from changes in the solvent environment. Addition of dimethyl sulfoxide (DMSO) elongates the bridging bond, presumably as a result of lessened solvation to the nonbridging oxygens and conservation of bond order to phosphorus. Finally, we have addressed the relationship between ground-state bonding properties and reactivity, as changing the leaving group substituent and adding DMSO have large rate effects, and it was previously proposed that lengthening of the bond to be broken is the cause of the increased reactivity. The results herein suggest, however, that the change in the bridging bond energy is small compared to the changes in energy that accompany the observed reactivity differences. Further analysis indicates that electrostatic interactions can provide a common driving force underlying both bond lengthening and the observed rate increases. We suggest that ground-state distortions of substrates bound to enzymes can provide a readout of the electrostatic active site environment, an environment that

  8. Small sensor probe for monitoring the space electromagnetic environments by the application of the miniaturized plasma wave receiver

    NASA Astrophysics Data System (ADS)

    Kojima, Hirotsugu; Fukuhara, Hajime; Okada, Satoshi; Yagitani, Satoshi; Ikeda, Hirokazu; Miyake, Yohei; Usui, Hideyuki; Yamakawa, Hiroshi; Ueda, Yoshikatsu

    2010-05-01

    Plasma waves act as the medium in the transport of kinetic energies through wave-particle interactions in space plasmas. Therefore, most of the space missions to investigate space plasmas carry the onboard plasma wave receivers, which is a kind of radio receivers with very high sensitivities. Recently, the downsized satellites in science missions such as formation flights and small satellites require the further reduction of power and mass budget for onboard instruments. We also face the similar requirement from the lack of the spacecraft resources in planetary missions. To meet the requirement, we developed the very small plasma wave receiver using the analogue ASIC (Application Specific Integrated Circuit) technology. Since the plasma wave receiver needs to receive very weak signals in the various frequency ranges, it accommodates filters with different frequency responses, low noise amplifiers with high gains and oscillators. This leads to the large occupation of the board by the analogue circuits. Therefore, the breakthrough to the extreme miniaturization of the plasma wave receiver does not occur without the miniaturization of the analogue electronic circuit. We have already confirmed the feasibility in realizing six channels (three for electric fields and three for magnetic fields) of waveform receivers inside the small chip with the size of 3mm x 3mm. The developed waveform receiver shows the good feature enough for the use in scientific missions. This success in the miniaturization of plasma wave receivers allow us to develop a new system measuring plasma waves in multiple points. Based on the technology of the miniaturization of plasma wave receivers, we propose a new system for monitoring the electromagnetic environment in space. We address it MSEE (Monitor System for space Electromagnetic Environments). The MSEE is a kind of the sensor network system in space. It consists of palm-sized sensor nodes, which are randomly distributed in the target area. The

  9. Real space tests of the statistical isotropy and Gaussianity of the Wilkinson Microwave Anisotropy Probe cosmic microwave background data

    SciTech Connect

    Lew, Bartosz

    2008-08-15

    We introduce and analyze a method for testing statistical isotropy and Gaussianity and apply it to the Wilkinson Microwave Anisotropy Probe (WMAP) cosmic microwave background (CMB) foreground reduced temperature maps. We also test cross-channel difference maps to constrain levels of residual foreground contamination and systematic uncertainties. We divide the sky into regions of varying size and shape and measure the first four moments of the one-point distribution within these regions, and using their simulated spatial distributions we test the statistical isotropy and Gaussianity hypotheses. By randomly varying orientations of these regions, we sample the underlying CMB field in a new manner, that offers a richer exploration of the data content, and avoids possible biasing due to a single choice of sky division. In our analysis we account for all two-point correlations between different regions and also show the impact on the results when these correlations are neglected. The statistical significance is assessed via comparison with realistic Monte Carlo simulations. We find the three-year WMAP maps to agree well with the isotropic, Gaussian random field simulations as probed by regions corresponding to the angular scales ranging from 6 Degree-Sign to 30 Degree-Sign at 68% confidence level (CL). We report a strong, anomalous (99.8% CL) dipole 'excess' in the V band of the three-year WMAP data and also in the V band of the WMAP five-year data (99.3% CL). Using our statistics, we notice large scale hemispherical power asymmetry, and find that it is not highly statistically significant in the WMAP three-year data ( Less-Than-Or-Equivalent-To 97%) at scales l{<=}40. The significance is even smaller if multipoles up to l=1024 are considered ({approx}90% CL). We give constraints on the amplitude of the previously proposed CMB dipole modulation field parameter. We find some hints of foreground contamination in the form of a locally strong, anomalous kurtosis excess in

  10. Effects of target fragmentation on evaluation of LET spectra from space radiations: implications for space radiation protection studies

    NASA Technical Reports Server (NTRS)

    Cucinotta, F. A.; Wilson, J. W.; Shinn, J. L.; Badavi, F. F.; Badhwar, G. D.

    1996-01-01

    We present calculations of linear energy transfer (LET) spectra in low earth orbit from galactic cosmic rays and trapped protons using the HZETRN/BRYNTRN computer code. The emphasis of our calculations is on the analysis of the effects of secondary nuclei produced through target fragmentation in the spacecraft shield or detectors. Recent improvements in the HZETRN/BRYNTRN radiation transport computer code are described. Calculations show that at large values of LET (> 100 keV/micrometer) the LET spectra seen in free space and low earth orbit (LEO) are dominated by target fragments and not the primary nuclei. Although the evaluation of microdosimetric spectra is not considered here, calculations of LET spectra support that the large lineal energy (y) events are dominated by the target fragments. Finally, we discuss the situation for interplanetary exposures to galactic cosmic rays and show that current radiation transport codes predict that in the region of high LET values the LET spectra at significant shield depths (> 10 g/cm2 of Al) is greatly modified by target fragments. These results suggest that studies of track structure and biological response of space radiation should place emphasis on short tracks of medium charge fragments produced in the human body by high energy protons and neutrons.

  11. Effects of target fragmentation on evaluation of LET spectra from space radiations: implications for space radiation protection studies

    NASA Technical Reports Server (NTRS)

    Cucinotta, F. A.; Wilson, J. W.; Shinn, J. L.; Badavi, F. F.; Badhwar, G. D.

    1996-01-01

    We present calculations of linear energy transfer (LET) spectra in low earth orbit from galactic cosmic rays and trapped protons using the HZETRN/BRYNTRN computer code. The emphasis of our calculations is on the analysis of the effects of secondary nuclei produced through target fragmentation in the spacecraft shield or detectors. Recent improvements in the HZETRN/BRYNTRN radiation transport computer code are described. Calculations show that at large values of LET (> 100 keV/micrometer) the LET spectra seen in free space and low earth orbit (LEO) are dominated by target fragments and not the primary nuclei. Although the evaluation of microdosimetric spectra is not considered here, calculations of LET spectra support that the large lineal energy (y) events are dominated by the target fragments. Finally, we discuss the situation for interplanetary exposures to galactic cosmic rays and show that current radiation transport codes predict that in the region of high LET values the LET spectra at significant shield depths (> 10 g/cm2 of Al) is greatly modified by target fragments. These results suggest that studies of track structure and biological response of space radiation should place emphasis on short tracks of medium charge fragments produced in the human body by high energy protons and neutrons.

  12. A case study on the use of a formative assessment probe to determine the presence of science misconceptions in elementary school students: Implications for teaching and curriculum

    NASA Astrophysics Data System (ADS)

    Lambi, Elizabeth A.

    misconceptions. Use of a two-tiered assessment, such as the probe used in this study, will allow the teacher to gain insight into the student's level of understanding in many different concepts in science. Once the misconception is identified, it can then be corrected with additional instruction. Implications of the study included the need for professional development, the alignment of curriculum, and the need to focus attention on science literacy as the goal of science education.

  13. Space Science

    NASA Image and Video Library

    2003-07-11

    The space vehicle for Gravity Probe B (GP-B) arrives at the launch site at Vandenburg Air Force Base. GP-B is the relativity experiment being developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Scheduled for launch in 2003 and managed for NASA by the Marshall Space Flight Center, development of the GP-B is the responsibility of Stanford University, with major subcontractor Lockheed Martin Corporation.

  14. Space Science

    NASA Image and Video Library

    2000-08-01

    The Gravity Probe B (GP-B) is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein’s general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth’s rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. In this photograph, the completed space vehicle is undergoing thermal vacuum environment testing. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Underwood, Lockheed Martin Corporation.)

  15. Space Science

    NASA Image and Video Library

    2004-01-01

    In this photo, the Gravity Probe B (GP-B) space vehicle is completed during the solar array installation. The GP-B is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein’s general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth’s rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. GP-B is scheduled for launch in April 2004 and managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Underwood, Lockheed Martin Corporation).

  16. Fifty years of human space travel: implications for bone and calcium research.

    PubMed

    Smith, S M; Abrams, S A; Davis-Street, J E; Heer, M; O'Brien, K O; Wastney, M E; Zwart, S R

    2014-01-01

    Calcium and bone metabolism remain key concerns for space travelers, and ground-based models of space flight have provided a vast literature to complement the smaller set of reports from flight studies. Increased bone resorption and largely unchanged bone formation result in the loss of calcium and bone mineral during space flight, which alters the endocrine regulation of calcium metabolism. Physical, pharmacologic, and nutritional means have been used to counteract these changes. In 2012, heavy resistance exercise plus good nutritional and vitamin D status were demonstrated to reduce loss of bone mineral density on long-duration International Space Station missions. Uncertainty continues to exist, however, as to whether the bone is as strong after flight as it was before flight and whether nutritional and exercise prescriptions can be optimized during space flight. Findings from these studies not only will help future space explorers but also will broaden our understanding of the regulation of bone and calcium homeostasis on Earth.

  17. Euclidean sections of protein conformation space and their implications in dimensionality reduction.

    PubMed

    Duan, Mojie; Li, Minghai; Han, Li; Huo, Shuanghong

    2014-10-01

    Dimensionality reduction is widely used in searching for the intrinsic reaction coordinates for protein conformational changes. We find the dimensionality-reduction methods using the pairwise root-mean-square deviation (RMSD) as the local distance metric face a challenge. We use Isomap as an example to illustrate the problem. We believe that there is an implied assumption for the dimensionality-reduction approaches that aim to preserve the geometric relations between the objects: both the original space and the reduced space have the same kind of geometry, such as Euclidean geometry vs. Euclidean geometry or spherical geometry vs. spherical geometry. When the protein free energy landscape is mapped onto a 2D plane or 3D space, the reduced space is Euclidean, thus the original space should also be Euclidean. For a protein with N atoms, its conformation space is a subset of the 3N-dimensional Euclidean space R(3N). We formally define the protein conformation space as the quotient space of R(3N) by the equivalence relation of rigid motions. Whether the quotient space is Euclidean or not depends on how it is parameterized. When the pairwise RMSD is employed as the local distance metric, implicit representations are used for the protein conformation space, leading to no direct correspondence to a Euclidean set. We have demonstrated that an explicit Euclidean-based representation of protein conformation space and the local distance metric associated to it improve the quality of dimensionality reduction in the tetra-peptide and β-hairpin systems. © 2014 Wiley Periodicals, Inc.

  18. Status of Cardiovascular Issues Related to Space Flight: implications for Future Research Directions

    DTIC Science & Technology

    2009-01-01

    challenges. Published by Elsevier B.V. 1. Introduction A fundamental objective of the 2008 International Space Life Science Working Group (ISLSWG) meeting was...evidenced-based approach. 2. Defining the ‘most important’ questions Space life science research related to the identification of phys- iological...lar risks prioritized by NASA since these generally represent many of the concerns identified by most international space life science investigators

  19. Cancer Risk from Exposure to Galactic Cosmic Rays - Implications for Human Space Exploration

    NASA Technical Reports Server (NTRS)

    Cucinotta, Francis A.; Durant, marco

    2006-01-01

    Current space programs are shifting toward planetary exploration, and in particular towards human missions to the moon and Mars. However, space radiation is a major barrier to human exploration of the solar system because the biological effects of high-energy and charge (HZE) ions, which are the main contributors to radiation risks in deep space, are poorly understood. Predictions of the nature and magnitude of the risks posed by space radiation are subject to very large uncertainties. Great efforts have been dedicated worldwide in recent years toward a better understanding of the oncogenic potential of galactic cosmic rays. A review of the new results in this field will be presented here.

  20. Space Flight Calcium: Implications for Astronaut Health, Spacecraft Operations, and Earth

    PubMed Central

    Smith, Scott M.; McCoy, Torin; Gazda, Daniel; Morgan, Jennifer L. L.; Heer, Martina; Zwart, Sara R.

    2012-01-01

    The space flight environment is known to induce bone loss and, subsequently, calcium loss. The longer the mission, generally the more bone and calcium are lost. This review provides a history of bone and calcium studies related to space flight and highlights issues related to calcium excretion that the space program must consider so that urine can be recycled. It also discusses a novel technique using natural stable isotopes of calcium that will be helpful in the future to determine calcium and bone balance during space flight. PMID:23250146

  1. Space flight calcium: implications for astronaut health, spacecraft operations, and Earth.

    PubMed

    Smith, Scott M; McCoy, Torin; Gazda, Daniel; Morgan, Jennifer L L; Heer, Martina; Zwart, Sara R

    2012-12-18

    The space flight environment is known to induce bone loss and, subsequently, calcium loss. The longer the mission, generally the more bone and calcium are lost. This review provides a history of bone and calcium studies related to space flight and highlights issues related to calcium excretion that the space program must consider so that urine can be recycled. It also discusses a novel technique using natural stable isotopes of calcium that will be helpful in the future to determine calcium and bone balance during space flight.

  2. ALEX neutral beam probe

    SciTech Connect

    Pourrezaei, K.

    1982-01-01

    A neutral beam probe capable of measuring plasma space potential in a fully 3-dimensional magnetic field geometry has been developed. This neutral beam was successfully used to measure an arc target plasma contained within the ALEX baseball magnetic coil. A computer simulation of the experiment was performed to refine the experimental design and to develop a numerical model for scaling the ALEX neutral beam probe to other cases of fully 3-dimensional magnetic field. Based on this scaling a 30 to 50 keV neutral cesium beam probe capable of measuring space potential in the thermal barrier region of TMX Upgrade was designed.

  3. Synthesis-enabled probing of mitosene structural space leads to improved IC₅₀ over mitomycin C.

    PubMed

    Zheng, Zhitong; Touve, Mollie; Barnes, Josue; Reich, Norbert; Zhang, Liming

    2014-08-25

    A DNA crosslinking approach, which is distinct but related to the double alkylation by mitomycin C, involving a novel electrophilic spiro-cyclopropane intermediate is hypothesized. Rational design and substantial structural simplification permitted the expedient chemical synthesis and rapid discovery of MTSB-6, a mitomycin C analogue which is twice as potent as mitomycin C against the prostate cancer cells. MTSB-6 shows improvements in its selective action against noncancer prostate cells over mitomycin C. This hypothesis-driven discovery opens novel yet synthetically accessible mitosene structural space for discovering more potent and less toxic therapeutic candidates.

  4. CASSIOPE Enhanced Polar Outflow Probe (e-POP) Small Satellite Mission: Space Plasma Observations and International Collaborations

    NASA Astrophysics Data System (ADS)

    Yau, A. W.; James, H. G.

    2009-06-01

    In-situ observation of the micro-scale characteristics of plasma acceleration and related outflow processes is a primary scientific target of the Canadian Enhanced Polar Outflow Probe (e-POP) small satellite mission. The e-POP instrument payload will include imaging plasma and neutral particle sensors, magnetometers, dual-frequency GPS receivers, CCD cameras, a radio wave receiver and a beacon transmitter. The imaging plasma sensors will measure particle distributions and the magnetometers will measure field-aligned currents on the time scale of 10 ms and spatial scale of ~100 m. The CCD cameras will perform auroral imaging on the time scale of 100 ms and at spatial (pixel) resolution up to 0.4 km. The GPS and radio-wave receivers will perform near real-time imaging studies of the ionosphere in conjunction with ground-based radars, and the beacon transmitter in conjunction with ground receiving stations. The e-POP payload will be flown on the Canadian CASSIOPE small satellite, which is scheduled for launch in late 2008 into a polar orbit (325×1500 km, 80° inclination). International collaboration is an important and integral part of the e-POP mission strategy. Two of the 8 e-POP science instruments will be contributed by JAXA/ISAS, Japan, and Naval Research Laboratory, USA, respectively. Many of the planned e-POP investigations will entail coordinated observations using Canadian as well as foreign ground facilities, including magnetic and optical observatories, radars and heaters, such as the HAARP facility in Alaska, the EISCAT radar, and the NSF Antarctic facility. International collaboration in these investigations is expected to significantly enhance the science returns of the e-POP mission.

  5. Synthetic biology in space: considering the broad societal and ethical implications

    NASA Astrophysics Data System (ADS)

    Race, Margaret S.; Moses, Jacob; McKay, Christopher; Venkateswaran, Kasthuri J.

    2012-02-01

    Although the field of synthetic biology is still in its infancy, there are expectations for great advances in the coming decades, both on Earth and potentially in space. Promising applications for long duration space missions include a variety of biologically engineered products and biologically aided processes and technologies, which will undoubtedly be scrutinized for risks and benefits in the broad context of ethical, legal and social realms. By comparing and contrasting features of Earth-based and space-applied synthetic biology, it is possible to identify the likely similarities and differences, and to identify possible challenges ahead for space applications that will require additional research, both in the short and long terms. Using an analytical framework associated with synthetic biology and new technologies on Earth, this paper analyses the kinds of issues and concerns ahead, and identifies those areas where space applications may require additional examination. In general, while Earth- and space-based synthetic biology share many commonalities, space applications have additional challenges such as those raised by space microbiology and environmental factors, legal complications, planetary protection, lack of decision-making infrastructure(s), long duration human missions, terraforming and the possible discovery of extraterrestrial (ET) life. For synthetic biology, the way forward offers many exciting opportunities, but is not without legitimate concerns - for life, environments and society, both on Earth and beyond.

  6. Quantitative Aspects of Space Weathering: Implications for Regolith Breccia Meteorites and Asteroids

    NASA Technical Reports Server (NTRS)

    Noble, S. K.; Pieters, C. M.; Keller, L. P.

    2004-01-01

    Space weathering is defined as the physical and optical changes incurred by material exposed to the space environment. Through studies of lunar soils, these changes are becoming well understood. However, the effects of space weathering are dependent on the physical environment to which the host materials are exposed, and thus, the effects will likely vary from body to body. The optical effects of space weathering result from nanophase iron (npFe(sup 0)) created during micrometeorite bombardment and solar wind sputtering. In the asteroid belt, bodies are farther from the sun than our Moon, and are widely known to incur less solar wind implantation and sputtering. The velocity of impacts is smaller resulting in less melting and vaporization, and therefore fewer space weathering products. The impact rate in the asteroid belt is greater, which will result in more comminution, further diluting any weathering products. Ergo, asteroidal regoliths should contain fewer space weathering products than lunar soils. However, even very small degrees of space weathering can have dramatic consequences for the optical properties of soils. A discussion on the optical effects of space weathering is presented.

  7. Space Psychology: A New Frontier. Implications for the Profession of Psychology.

    ERIC Educational Resources Information Center

    Ponterotto, Joseph G.; Hayden, Davis C.

    As many of the physical problems of space travel are solved, scientists are beginning to address the psychological needs of the astronauts. While the last decade has produced technological advances making space travel and work a definite possibility, psychologists and the public are largely unaware of the psychological and socio-psychological…

  8. Creating a "Third Space" in Student Teaching: Implications for the University Supervisor's Status as Outsider

    ERIC Educational Resources Information Center

    Cuenca, Alexander; Schmeichel, Mardi; Butler, Brandon M.; Dinkelman, Todd; Nichols, Joseph R., Jr.

    2011-01-01

    The work of teacher education during student teaching typically takes place in two distinct "spaces": placement sites and college/university settings. The program featured in this article is structured in ways that clearly mark out those two spaces. Yet this configuration led our university supervisors, whose work primarily took place in the…

  9. Space Psychology: A New Frontier. Implications for the Profession of Psychology.

    ERIC Educational Resources Information Center

    Ponterotto, Joseph G.; Hayden, Davis C.

    As many of the physical problems of space travel are solved, scientists are beginning to address the psychological needs of the astronauts. While the last decade has produced technological advances making space travel and work a definite possibility, psychologists and the public are largely unaware of the psychological and socio-psychological…

  10. Creating a "Third Space" in Student Teaching: Implications for the University Supervisor's Status as Outsider

    ERIC Educational Resources Information Center

    Cuenca, Alexander; Schmeichel, Mardi; Butler, Brandon M.; Dinkelman, Todd; Nichols, Joseph R., Jr.

    2011-01-01

    The work of teacher education during student teaching typically takes place in two distinct "spaces": placement sites and college/university settings. The program featured in this article is structured in ways that clearly mark out those two spaces. Yet this configuration led our university supervisors, whose work primarily took place in the…

  11. Fifty years of human space travel: implications for bone and calcium research

    USDA-ARS?s Scientific Manuscript database

    Calcium and bone metabolism remain key concerns for space travelers, and ground-based models of space flight have provided a vast literature to complement the smaller set of reports from flight studies. Increased bone resorption and largely unchanged bone formation result in the loss of calcium and ...

  12. Critical roles for distance, task, and motion in space perception: initial conceptual framework and practical implications.

    PubMed

    DeLucia, Patricia R

    2008-10-01

    A conceptual framework of visual space perception is proposed. Prior studies suggest that the processes underlying space perception depend on viewing distance, the nature of a task, and the presence and nature of motion. Evidence from neuropsychological, neuroimaging, and behavioral studies is reviewed. A preliminary conceptual framework of space perception is proposed in which three critical factors of distance, task, and motion represent different dimensions. Different locations within the framework represent the involvement of different underlying processes. At one extreme, indirect perception underlies a stationary observer's perceptual judgments of stationary objects in far space. At the other extreme, direct perception underlies a moving observer's actions involving moving objects in near space. Between these extremes, both processes are utilized and allow for flexibility in human performance. Prior studies of space perception should be reevaluated based on viewing distances employed, the nature of the tasks, and the presence and nature of motion. Future studies of space perception should manipulate these variables. If, as proposed by the framework, observers use different underlying mechanisms to perceive near and far spaces and to perform different types of tasks, it becomes important to identify the limits of such mechanisms and to design technologies to accommodate those limits. For example, collision-avoidance warning systems may have to utilize different criteria for providing warnings at near versus far headways. Further study of the proposed framework will help improve the design of such technologies.

  13. Dynamics of Hierarchical Urban Green Space Patches and Implications for Management Policy

    PubMed Central

    Yu, Zhoulu; Wang, Yaohui; Deng, Jinsong; Shen, Zhangquan; Wang, Ke; Zhu, Jinxia; Gan, Muye

    2017-01-01

    Accurately quantifying the variation of urban green space is the prerequisite for fully understanding its ecosystem services. However, knowledge about the spatiotemporal dynamics of urban green space is still insufficient due to multiple challenges that remain in mapping green spaces within heterogeneous urban environments. This paper uses the city of Hangzhou to demonstrate an analysis methodology that integrates sub-pixel mapping technology and landscape analysis to fully investigate the spatiotemporal pattern and variation of hierarchical urban green space patches. Firstly, multiple endmember spectral mixture analysis was applied to time series Landsat data to derive green space coverage at the sub-pixel level. Landscape metric analysis was then employed to characterize the variation pattern of urban green space patches. Results indicate that Hangzhou has experienced a significant loss of urban greenness, producing a more fragmented and isolated vegetation landscape. Additionally, a remarkable amelioration of urban greenness occurred in the city core from 2002 to 2013, characterized by the significant increase of small-sized green space patches. The green space network has been formed as a consequence of new urban greening strategies in Hangzhou. These strategies have greatly fragmented the built-up areas and enriched the diversity of the urban landscape. Gradient analysis further revealed a distinct pattern of urban green space landscape variation in the process of urbanization. By integrating both sub-pixel mapping technology and landscape analysis, our approach revealed the subtle variation of urban green space patches which are otherwise easy to overlook. Findings from this study will help us to refine our understanding of the evolution of heterogeneous urban environments. PMID:28587309

  14. Dynamics of Hierarchical Urban Green Space Patches and Implications for Management Policy.

    PubMed

    Yu, Zhoulu; Wang, Yaohui; Deng, Jinsong; Shen, Zhangquan; Wang, Ke; Zhu, Jinxia; Gan, Muye

    2017-06-06

    Accurately quantifying the variation of urban green space is the prerequisite for fully understanding its ecosystem services. However, knowledge about the spatiotemporal dynamics of urban green space is still insufficient due to multiple challenges that remain in mapping green spaces within heterogeneous urban environments. This paper uses the city of Hangzhou to demonstrate an analysis methodology that integrates sub-pixel mapping technology and landscape analysis to fully investigate the spatiotemporal pattern and variation of hierarchical urban green space patches. Firstly, multiple endmember spectral mixture analysis was applied to time series Landsat data to derive green space coverage at the sub-pixel level. Landscape metric analysis was then employed to characterize the variation pattern of urban green space patches. Results indicate that Hangzhou has experienced a significant loss of urban greenness, producing a more fragmented and isolated vegetation landscape. Additionally, a remarkable amelioration of urban greenness occurred in the city core from 2002 to 2013, characterized by the significant increase of small-sized green space patches. The green space network has been formed as a consequence of new urban greening strategies in Hangzhou. These strategies have greatly fragmented the built-up areas and enriched the diversity of the urban landscape. Gradient analysis further revealed a distinct pattern of urban green space landscape variation in the process of urbanization. By integrating both sub-pixel mapping technology and landscape analysis, our approach revealed the subtle variation of urban green space patches which are otherwise easy to overlook. Findings from this study will help us to refine our understanding of the evolution of heterogeneous urban environments.

  15. Probing Effect of Salinity and pH on Surface Interactions between Air Bubbles and Hydrophobic Solids: Implications on Colloidal Assembly at Air/Water Interface.

    PubMed

    Cui, Xin; Shi, Chen; Zhang, Shuo; Xie, Lei; Liu, Jing; Jiang, Dazhi; Zeng, Hongbo

    2017-04-05

    In this work, bubble probe atomic force microscope (AFM) was employed to quantify the interactions between two air bubbles and between an air bubble and an octadecyltrichlorosilane (OTS)-hydrophobized mica under various aqueous conditions. The key parameters (e.g. surface potentials, decay length of hydrophobic attraction) were obtained by analyzing the measured forces through a theoretical model based on Reynolds lubrication theory and augmented Young-Laplace equation by including effect of disjoining pressure. The bubble-OTS hydrophobic attraction with a decay length of 1.0 nm was found to be independent of solution pH and salinity. These parameters were further used to predict the attachment of OTS-hydrophobized particles onto air/water interface, demonstrating that particle attachment driven by hydrophobic attraction could be facilitated by suppressing electrical double-layer repulsion at low pH or high salinity condition. This facile methodology can be readily extended to quantify interactions of many other colloidal particles with gas/water and oil/water interfaces, with implications on colloidal assembly at different interfaces in many engineering applications.

  16. Probing secondary glutaminyl cyclase (QC) inhibitor interactions applying an in silico-modeling/site-directed mutagenesis approach: implications for drug development.

    PubMed

    Koch, Birgit; Buchholz, Mirko; Wermann, Michael; Heiser, Ulrich; Schilling, Stephan; Demuth, Hans-Ulrich

    2012-12-01

    Glutaminyl cyclases (QCs) catalyze the formation of pyroglutamate-modified amyloid peptides deposited in neurodegenerative disorders such as Alzheimer's disease. Inhibitors of QC are currently in development as potential therapeutics. The crystal structures of the potent inhibitor PBD150 bound to human and murine QC (hQC, mQC) have been described recently. The binding modes of a dimethoxyphenyl moiety of the inhibitor are significantly different between the structures, which contrasts with a similar K(i) value. We show the conformation of PBD150 prone to disturbance by protein-protein interactions within the crystals. Semi-empirical calculations of the enzyme-inhibitor interaction within the crystal suggest significant differences in the dissociation constants between the binding modes. To probe for interactions in solution, a site-directed mutagenesis on hQC was performed. The replacement of F325 and I303 by alanine or asparagine resulted in a 800-fold lower activity of the inhibitor, whereas the exchange of S323 by alanine or valine led to a 20-fold higher activity of PBD150. The results provide an example of deciphering the interaction mode between a target enzyme and lead substance in solution, if co-crystallization does not mirror such interactions properly. Thus, the study might provide implications for rapid screening of binding modes also for other drug targets.

  17. A review of adaptive change in musculoskeletal impedance during space flight and associated implications for postflight head movement control

    NASA Technical Reports Server (NTRS)

    McDonald, P. V.; Bloomberg, J. J.; Layne, C. S.

    1997-01-01

    We present a review of converging sources of evidence which suggest that the differences between loading histories experienced in 1-g and weightlessness are sufficient to stimulate adaptation in mechanical impedance of the musculoskeletal system. As a consequence of this adaptive change we argue that we should observe changes in the ability to attenuate force transmission through the musculoskeletal system both during and after space flight. By focusing attention on the relation between human sensorimotor activity and support surfaces, the importance of controlling mechanical energy flow through the musculoskeletal system is demonstrated. The implications of such control are discussed in light of visual-vestibular function in the specific context of head and gaze control during postflight locomotion. Evidence from locomotory biomechanics, visual-vestibular function, ergonomic evaluations of human vibration, and specific investigations of locomotion and head and gaze control after space flight, is considered.

  18. Building a quality culture in the Office of Space Flight: Approach, lessons learned and implications for the future

    NASA Technical Reports Server (NTRS)

    Roberts, C. Shannon

    1992-01-01

    The purpose of this paper is to describe the approach and lessons learned by the Office of Space Flight (OSF), National Aeronautics and Space Administration (NASA), in its introduction of quality. In particular, the experience of OSF Headquarters is discussed as an example of an organization within NASA that is considering both the business and human elements of the change and the opportunities the quality focus presents to improve continuously. It is hoped that the insights shared will be of use to those embarking upon similar cultural changes. The paper is presented in the following parts: the leadership challenge; background; context of the approach to quality; initial steps; current initiatives; lessons learned; and implications for the future.

  19. A review of adaptive change in musculoskeletal impedance during space flight and associated implications for postflight head movement control

    NASA Technical Reports Server (NTRS)

    McDonald, P. V.; Bloomberg, J. J.; Layne, C. S.

    1997-01-01

    We present a review of converging sources of evidence which suggest that the differences between loading histories experienced in 1-g and weightlessness are sufficient to stimulate adaptation in mechanical impedance of the musculoskeletal system. As a consequence of this adaptive change we argue that we should observe changes in the ability to attenuate force transmission through the musculoskeletal system both during and after space flight. By focusing attention on the relation between human sensorimotor activity and support surfaces, the importance of controlling mechanical energy flow through the musculoskeletal system is demonstrated. The implications of such control are discussed in light of visual-vestibular function in the specific context of head and gaze control during postflight locomotion. Evidence from locomotory biomechanics, visual-vestibular function, ergonomic evaluations of human vibration, and specific investigations of locomotion and head and gaze control after space flight, is considered.

  20. Exercise Countermeasures for Bone Loss During Space Flight: A Method for the Study of Ground Reaction Forces and Their Implications for Bone Strain

    NASA Technical Reports Server (NTRS)

    Peterman, M.; McCrory, J. L.; Sharkey, N. A.; Piazza, S.; Cavanagh, P. R.

    1999-01-01

    The human zero-gravity locomotion simulator and the cadaver simulator offer a powerful combination for the study of the implications of exercise for maintaining bone quality during space flight. Such studies, when compared with controlled in-flight exercise programs, could help in the identification of a strain threshold for the prevention of bone loss during space flight.

  1. Probing Seismic Solar Analogues Through Observations With The NASA Kepler Space Telescope and Hermes High-Resolution Spectrograph

    NASA Astrophysics Data System (ADS)

    Beck, P. G.; Salabert, D.; Garcia, R. A.; do Nascimento, J., Jr.; Duarte, T. S. S.; Mathis, S.; Regulo, C.; Ballot, J.; Egeland, R.; Castro, M.; Pérez-Herńandez, F.,; Creevey, O.; Tkachenko, A.; van Reeth, T.; Bigot, L.; Corsaro, E.; Metcalfe, T.; Mathur, S.; Palle, P. L.; Allende Prieto, C.; Montes, D.; Johnston, C.; Andersen, M. F.; van Winckel, H.

    2016-11-01

    Stars similar to the Sun, known as solar analogues, provide an excellent opportunity to study the preceding and following evolutionary phases of our host star. The unprecedented quality of photometric data collected by the Kepler NASA mission allows us to characterise solar-like stars through asteroseismology and study diagnostics of stellar evolution, such as variation of magnetic activity, rotation and the surface lithium abundance. In this project, presented in a series of papers by Salabert et al (2016ab) and Beck et al. (2016ab), we investigate the link between stellar activity, rotation, lithium abundance and oscillations in a group of 18 solar-analogue stars through space photometry, obtained with the NASA Kepler space telescope and from currently 50+ hours of ground-based, high-resolution spectroscopy with the Hermes instrument. In these proceedings, we first discuss the selection of the stars in the sample, observations and calibrations and then summarise the main results of the project. By investigating the chromospheric and photospheric activity of the solar analogues in this sample, it was shown that for a large fraction of these stars the measured activity levels are compatible to levels of the 11-year solar activity cycle 23. A clear correlation between the lithium abundance and surface rotation was found for rotation periods shorter than the solar value. Comparing the lithium abundance measured in the solar analogues to evolutionary models with the Toulouse-Geneva Evolutionary Code (TGEC), we found that the solar models calibrated to the Sun also correctly describe the set of solar/stellar analogs showing that they share the same internal mixing physics. Finally, the star KIC3241581 and KIC10644353 are discussed in more detail.

  2. Status of cardiovascular issues related to space flight: Implications for future research directions.

    PubMed

    Convertino, Victor A

    2009-10-01

    Compromised cardiovascular performance, occurrence of serious cardiac dysrhythmias, cardiac atrophy, orthostatic intolerance, reduced aerobic capacity, operational impacts of regular physical exercise, and space radiation are risks of space flight to the cardiovascular system identified in the 2007 NASA Human Integrated Research Program. An evidence-based approach to identify the research priorities needed to resolve those cardiovascular risks that could most likely compromise the successful completion of extended-duration space missions is presented. Based on data obtained from astronauts who have flown in space, there is no compelling experimental evidence to support significant occurrence of autonomic or vascular dysfunction, cardiac dysrhythmias, or manifestation of asymptomatic cardiovascular disease. The operational impact of prolonged daily exercise and space radiation needs to be defined. In contrast, data from the literature support the notion that the highest probability of occurrence and operational impact with space flight involving cardiovascular risks to astronaut health, safety and operational performance are reduced orthostatic tolerance and aerobic capacity, the resource cost of effective countermeasures, and the potential effects of space radiation. Future research should focus on these challenges.

  3. Global Survey on Future Trends in Human Spaceflight: the Implications for Space Tourism

    NASA Astrophysics Data System (ADS)

    Gurtuna, O.; Garneau, S.

    2002-01-01

    With the much-publicized first ever space tourist flight, of Dennis Tito, and the announcement of the second space tourist flight to take place in April 2002, it is clear that an alternative motivation for human spaceflight has emerged. Human spaceflight is no longer only about meeting the priorities of national governments and space agencies, but is also about the tangible possibility of ordinary people seeing the Earth from a previously exclusive vantage point. It is imperative that major space players look beyond the existing human spaceflight rationale to identify some of the major driving forces behind space tourism, including the evolving market potential and developments in enabling technologies. In order to determine the influence of these forces on the future of commercial human spaceflight, the responses of a Futuraspace survey on future trends in human spaceflight are analyzed and presented. The motivation of this study is to identify sought-after space destinations, explore the expected trends in enabling technologies, and understand the future role of emerging space players. The survey will reflect the opinions of respondents from around the world including North America, Europe (including Russia) and Asia. The profiles of targeted respondents from space industry, government and academia are high-level executives/managers, senior researchers, as well as former and current astronauts. The survey instrument is a questionnaire which is validated by a pilot study. The sampling method is non-probabilistic, targeting as many space experts as possible who fit our intended respondent profile. Descriptive and comparative statistical analysis methods are implemented to investigate both global and regional perceptions of future commercial trends in human spaceflight. This study is not intended to be a formal market study of the potential viability of the space tourism market. Instead, the focus is on the future trends of human spaceflight, by drawing on the

  4. The Relationship between Student Performance under Training Conditions and under Probe Conditions and the Implications for Interpretations of Student Performance Data.

    ERIC Educational Resources Information Center

    Farlow, Leslie J.; And Others

    1991-01-01

    Students with severe/profound mental retardation performed functional tasks under training or probe conditions. Analysis of nine students' records indicated that students do not react to probe conditions as if they were extinction conditions; training data do not consistently reflect performance under probe conditions; and data collected under…

  5. Legal and Political Implications of Offensive Actions from and Against the Space Segment

    NASA Astrophysics Data System (ADS)

    de Angelis, Iole M.

    2002-01-01

    Hundreds of satellites now present in space benefit the people of the world economically, scientifically and by their contribution to international security. So far, activities in space have proceeded without much conflict. Means have been found for regulation and agreement to minimize interference in the radio spectrum, while making more efficient use of limited spectrum resources. The Outer Space Treaty bars the stationing of nuclear weapons in space, or other weapons of mass destruction. Nations are responsible for damages that their space activities may cause to others, perhaps including destruction of the space assets of another nation. Today, maintaining the peaceful use of space is becoming more complicated by the privatisation of the notion of security by commercial actors and by the emerging of high technology non-state threats, that are not bind by international treaties. SPACE WEAPONS The Outer Space Treaty had been adopted to avoid the possible denial of peaceful uses of outer space, and because, technically speaking, jeopardizing a satellite was a difficult task to perform. For example, an orbiting laser might take hours or days for the Earth to rotate and the laser to be at an appropriate point in its orbit to threaten a target on the ground or in the air. Conversely, a substantial number of such weapons in space might be able to destroy targets within minutes of the command to do so, if the targets were visible and not below clouds. It is currently very difficult to oppose space weapons. For this reason, they could be significantly effective against an adversary. However, there are several obvious ways to counter nation controlled space-based weapons: anti-satellite systems, economic and technological blockade and an international legal system that forbids/restricts such weapons. The problem remains for non-state international actors which are not bound by international treaties. For this reason, the principle established by the United States to tie

  6. Cancer risk from exposure to galactic cosmic rays: implications for space exploration by human beings.

    PubMed

    Cucinotta, Francis A; Durante, Marco

    2006-05-01

    Space programmes are shifting toward planetary exploration, and in particular towards missions by human beings to the moon and Mars. However, exposure to space radiation is an important barrier to exploration of the solar system by human beings because of the biological effects of high-energy heavy ions. These ions have a high charge and energy, are the main contributors to radiation risk in deep space, and their biological effects are understood poorly. Predictions of the nature and magnitude of risks posed by exposure to radiation in space are subject to many uncertainties. In recent years, worldwide efforts have focussed on an increased understanding of the oncogenic potential of galactic cosmic rays. A review of the new results in this specialty will be presented here.

  7. Autonomic neural control and implications for remote medical monitoring in space.

    PubMed

    Cooke, William H

    2007-07-01

    Long-duration space travel or extended stays on the moon or Mars will pose new challenges for maintaining and monitoring the health status of astronauts. Remote medical monitoring systems will need to be developed for a number of applications, including providing decision support for care-givers in the event of traumatic injury in space. The focus of this brief review is to introduce potential methods of monitoring astronaut status remotely from simple ECG recordings.

  8. Mammal diversity and metacommunity dynamics in urban green spaces: implications for urban wildlife conservation.

    PubMed

    Gallo, Travis; Fidino, Mason; Lehrer, Elizabeth W; Magle, Seth B

    2017-08-21

    As urban growth expands and natural environments fragment, it is essential to understand the ecological roles fulfilled by urban green spaces. To evaluate how urban green spaces function as wildlife habitat, we estimated mammal diversity and metacommunity dynamics in city parks, cemeteries, golf courses, and natural areas throughout the greater Chicago, IL, USA region. We found similar α-diversity (with the exception of city parks), but remarkably dissimilar communities in different urban green spaces. Additionally, the type of urban green space greatly influenced species colonization and persistence rates. For example, coyotes (Canis latrans) had the highest, but white-tailed deer (Odocoileus virginianus) the lowest, probability of persistence in golf courses compared to other green space types. Further, most species had a difficult time colonizing city parks even when sites were seemingly available. Our results indicate that urban green spaces contribute different, but collectively important, habitats for maintaining and conserving biodiversity in cities. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  9. Valuing urban open space using the travel-cost method and the implications of measurement error.

    PubMed

    Hanauer, Merlin M; Reid, John

    2017-08-01

    Urbanization has placed pressure on open space within and adjacent to cities. In recent decades, a greater awareness has developed to the fact that individuals derive multiple benefits from urban open space. Given the location, there is often a high opportunity cost to preserving urban open space, thus it is important for both public and private stakeholders to justify such investments. The goals of this study are twofold. First, we use detailed surveys and precise, accessible, mapping methods to demonstrate how travel-cost methods can be applied to the valuation of urban open space. Second, we assess the degree to which typical methods of estimating travel times, and thus travel costs, introduce bias to the estimates of welfare. The site we study is Taylor Mountain Regional Park, a 1100-acre space located immediately adjacent to Santa Rosa, California, which is the largest city (∼170,000 population) in Sonoma County and lies 50 miles north of San Francisco. We estimate that the average per trip access value (consumer surplus) is $13.70. We also demonstrate that typical methods of measuring travel costs significantly understate these welfare measures. Our study provides policy-relevant results and highlights the sensitivity of urban open space travel-cost studies to bias stemming from travel-cost measurement error. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Implications of number-space synesthesia on the automaticity of numerical processing.

    PubMed

    Gertner, Limor; Henik, Avishai; Reznik, Daniel; Cohen Kadosh, Roi

    2013-05-01

    Number-space synesthetes visualize numbers in specific spatial configurations. Their spatial-numerical perceptions are assumed to be automatic in nature and have been found to affect performance in various numerical tasks. The current study tested whether synesthetic number-space associations can modulate the well-established Size Congruency Effect (SiCE), which is considered to be an indication for the automaticity of numerical processing. Two groups, number-space synesthetes and matched controls, were tested on a numerical Stroop task (Henik and Tzelgov, 1982). In separate blocks, participants were presented with two digits and asked to make comparative judgments regarding either numerical values (numerical comparison) or physical size (physical comparison). Both dimensions were manipulated orthogonally, creating three congruency levels: congruent (e.g., 2 7), incongruent (e.g., 2 7) and neutral (e.g., 2 2 and 2 7 for physical and numerical blocks, respectively). For the numerical block, both synesthetes and controls showed the classic SiCE, indicating similar automatic processing of physical magnitude. However, in the physical block, synesthetes showed a lack of automatic numerical magnitude processing when the numbers to be compared were presented incompatibly with their relative position on the synesthetic number-form. This finding strongly suggests that synesthetes' number-space perceptions affect their ability to automatically process the semantic meaning of numerals. The involvement of space in automatic magnitude processing for number-space synesthetes and non-synesthetes is discussed.

  11. Implications of number-space synesthesia on the automaticity of numerical processing

    PubMed Central

    Gertner, Limor; Henik, Avishai; Reznik, Daniel; Cohen Kadosh, Roi

    2013-01-01

    Number-space synesthetes visualize numbers in specific spatial configurations. Their spatial-numerical perceptions are assumed to be automatic in nature and have been found to affect performance in various numerical tasks. The current study tested whether synesthetic number-space associations can modulate the well-established Size Congruency Effect (SiCE), which is considered to be an indication for the automaticity of numerical processing. Two groups, number-space synesthetes and matched controls, were tested on a numerical Stroop task (Henik and Tzelgov, 1982). In separate blocks, participants were presented with two digits and asked to make comparative judgments regarding either numerical values (numerical comparison) or physical size (physical comparison). Both dimensions were manipulated orthogonally, creating three congruency levels: congruent (e.g., 2 7), incongruent (e.g., 2 7) and neutral (e.g., 2 2 and 2 7 for physical and numerical blocks, respectively). For the numerical block, both synesthetes and controls showed the classic SiCE, indicating similar automatic processing of physical magnitude. However, in the physical block, synesthetes showed a lack of automatic numerical magnitude processing when the numbers to be compared were presented incompatibly with their relative position on the synesthetic number-form. This finding strongly suggests that synesthetes’ number-space perceptions affect their ability to automatically process the semantic meaning of numerals. The involvement of space in automatic magnitude processing for number-space synesthetes and non-synesthetes is discussed. PMID:22578710

  12. PROBING VERY BRIGHT END OF GALAXY LUMINOSITY FUNCTION AT z {approx}> 7 USING HUBBLE SPACE TELESCOPE PURE PARALLEL OBSERVATIONS

    SciTech Connect

    Yan Haojing; Yan Lin; Zamojski, Michel A.; Windhorst, Rogier A.; McCarthy, Patrick J.; Fan Xiaohui; Dave, Romeel; Roettgering, Huub J. A.; Koekemoer, Anton M.; Robertson, Brant E.; Cai Zheng

    2011-02-10

    We report the first results from the Hubble Infrared Pure Parallel Imaging Extragalactic Survey, which utilizes the pure parallel orbits of the Hubble Space Telescope to do deep imaging along a large number of random sightlines. To date, our analysis includes 26 widely separated fields observed by the Wide Field Camera 3, which amounts to 122.8 arcmin{sup 2} in total area. We have found three bright Y{sub 098}-dropouts, which are candidate galaxies at z {approx}> 7.4. One of these objects shows an indication of peculiar variability and its nature is uncertain. The other two objects are among the brightest candidate galaxies at these redshifts known to date (L>2L*). Such very luminous objects could be the progenitors of the high-mass Lyman break galaxies observed at lower redshifts (up to z {approx} 5). While our sample is still limited in size, it is much less subject to the uncertainty caused by 'cosmic variance' than other samples because it is derived using fields along many random sightlines. We find that the existence of the brightest candidate at z {approx} 7.4 is not well explained by the current luminosity function (LF) estimates at z {approx} 8. However, its inferred surface density could be explained by the prediction from the LFs at z {approx} 7 if it belongs to the high-redshift tail of the galaxy population at z {approx} 7.

  13. Exo-C: a probe-scale space observatory for direct imaging and spectroscopy of extrasolar planetary systems

    NASA Astrophysics Data System (ADS)

    Stapelfeldt, Karl R.; Dekens, Frank G.; Brenner, Michael P.; Warfield, Keith R.; Belikov, Ruslan; Brugarolas, Paul B.; Bryden, Geoffrey; Cahoy, Kerri L.; Chakrabarti, Supriya; Dubovitsky, Serge; Effinger, Robert T.; Hirsch, Brian; Kissil, Andrew; Krist, John E.; Lang, Jared J.; Marley, Mark S.; McElwain, Michael W.; Meadows, Victoria S.; Nissen, Joel; Oseas, Jeffrey M.; Pong, Chris; Serabyn, Eugene; Sunada, Eric; Trauger, John T.; Unwin, Stephen C.

    2015-09-01

    "Exo-C" is NASAs first community study of a modest aperture space telescope mission that is optimized for high contrast observations of exoplanetary systems. The mission will be capable of taking optical spectra of nearby exoplanets in reflected light, discovering previously undetected planets, and imaging structure in a large sample of circumstellar disks. It will obtain unique science results on planets down to super-Earth sizes and serve as a technology pathfinder toward an eventual flagship-class mission to find and characterize habitable Earth-like exoplanets. We present the mission/payload design and highlight steps to reduce mission cost/risk relative to previous mission concepts. Key elements are an unobscured telescope aperture, an internal coronagraph with deformable mirrors for precise wavefront control, and an orbit and observatory design chosen for high thermal stability. Exo-C has a similar telescope aperture, orbit, lifetime, and spacecraft bus requirements to the highly successful Kepler mission (which is our cost reference). Much of the needed technology development is being pursued under the WFIRST coronagraph study and would support a mission start in 2017, should NASA decide to proceed. This paper summarizes the study final report completed in March 2015.

  14. Space Science

    NASA Image and Video Library

    2002-10-01

    Gravity Probe-B (GP-B) is the relativity experiment being developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies -- technologies that are already enlivening other branches of science and engineering. Scheduled for launch in 2003 and managed for NASA by Marshall Space Flight Center, development of the GP-B is the responsibility of Stanford University, with major subcontractor Lockheed Martin Corporation.

  15. Space Science

    NASA Image and Video Library

    2002-10-01

    Gravity Probe-B (GP-B) is the relativity experiment being developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies -- technologies that are already enlivening other branches of science and engineering. Scheduled for launch in 2003 and managed for NASA by Marshall Space Flight Center, development of GP-B is the responsibility of Stanford University, with major subcontractor Lockheed Martin Corporation.

  16. Space Science

    NASA Image and Video Library

    2003-01-01

    The Gravity Probe B (GP-B) is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein’s general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth’s rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. This photograph is a close up of a niobium-coated gyroscope motor and its housing halves. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Don Harley.)

  17. Space Science

    NASA Image and Video Library

    2002-10-01

    Gravity Probe-B (GP-B) is the relativity experiment being developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies -- technologies that are already enlivening other branches of science and engineering. Scheduled for launch in 2003 and managed for NASA by the Marshall Space Flight Center, development of GP-B is the responsibility of Stanford University, with major subcontractor Lockheed Martin Corporation.

  18. Space Science

    NASA Image and Video Library

    2000-08-01

    The Gravity Probe B (GP-B) is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein’s general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth’s rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. In this photograph, Stanford engineer, Chris Gray, is inspecting the number 4 gyro under monochromatic light. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Leese, Stanford University.)

  19. Space Science

    NASA Image and Video Library

    2001-01-01

    Gravity Probe B (GP-B) is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein’s general theory of relativity. This photograph is of the Gravity Probe B flight dewar, a metal container made like a vacuum bottle that is used especially for storing liquefied gases, that will maintain the experiment at a temperature just above absolute zero, staying cold for two years. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth’s rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies -- technologies that are already enlivening other branches of science and engineering. Launched in 2004 and managed for NASA by the Marshall Space Flight Center, development of the GP-B is the responsibility of Stanford University, with major subcontractor Lockheed Martin Corporation. (Photo Credit: Lockheed Martin Corporation/R. Underwood)

  20. Subthalamic Stimulation Reduces Vowel Space at the Initiation of Sustained Production: Implications for Articulatory Motor Control in Parkinson's Disease.

    PubMed

    Sidtis, John J; Alken, Amy G; Tagliati, Michele; Alterman, Ron; Van Lancker Sidtis, Diana

    2016-03-19

    Stimulation of the subthalamic nuclei (STN) is an effective treatment for Parkinson's disease, but complaints of speech difficulties after surgery have been difficult to quantify. Speech measures do not convincingly account for such reports. This study examined STN stimulation effects on vowel production, in order to probe whether DBS affects articulatory posturing. The objective was to compare positioning during the initiation phase with the steady prolongation phase by measuring vowel spaces for three "corner" vowels at these two time frames. Vowel space was measured over the initial 0.25 sec of sustained productions of high front (/i/), high back (/u/) and low vowels (/a/), and again during a 2 sec segment at the midpoint. Eight right-handed male subjects with bilateral STN stimulation and seven age-matched male controls were studied based on their participation in a larger study that included functional imaging. Mean values: age = 57±4.6 yrs; PD duration = 12.3±2.7 yrs; duration of DBS = 25.6±21.2 mos, and UPDRS III speech score = 1.6±0.7. STN subjects were studied off medication at their therapeutic DBS settings and again with their stimulators off, counter-balanced order. Vowel space was larger in the initiation phase compared to the midpoint for both the control and the STN subjects off stimulation. With stimulation on, however, the initial vowel space was significantly reduced to the area measured at the mid-point. For the three vowels, the acoustics were differentially affected, in accordance with expected effects of front versus back position in the vocal tract. STN stimulation appears to constrain initial articulatory gestures for vowel production, raising the possibility that articulatory positions normally used in speech are similarly constrained.

  1. Functional implications of variation in tooth spacing and crown size in pinnipedimorpha (mammalia: carnivora).

    PubMed

    Churchill, Morgan; Clementz, Mark T

    2015-05-01

    Pinnipeds (seals, sea lions, and walruses) show variation in tooth morphology that relates to ecology. However, crown size and spacing are two aspects of morphology that have not been quantified in prior studies. We measured these characters for nearly all extant pinnipeds and three fossil taxa and then determined the principal sources of variation in tooth size and spacing using principal components (PCAs) and hierarchical cluster analysis (HCA). PCA and HCA showed that species sorted into three groups: taxa with small crowns and large diastemata, taxa with large crowns and small diastemata, and taxa that fell between these two extremes. We then performed discriminant function analysis (DFA) to determine if tooth morphology correlated with foraging strategy or diet. DFA results indicated weak correlation with diet, and stronger correlation with prey capture strategies. Tooth size and spacing were most strongly correlated with the importance of teeth in prey acquisition, with tooth size decreasing and tooth spacing increasing as teeth become less necessary in capturing food items. Taxa which relied on teeth for filtering prey from the water column or processing larger or tougher food items generally had larger crowns and smaller tooth spacing then taxa which swallowed prey whole. We found the fossil taxa Desmatophoca and Enaliarctos were most similar in tooth morphology to extant otariids, suggesting that both taxa were generalist feeders. This study established the relationship between tooth size and feeding behavior, and provides a new tool to explore the paleoecology of fossil pinnipeds and other aquatic tetrapods.

  2. Denonvilliers' space expansion by transperineal injection of hydrogel: implications for focal therapy of prostate cancer.

    PubMed

    de Castro Abreu, Andre Luis; Ma, Yanling; Shoji, Sunao; Marien, Arnaud; Leslie, Scott; Gill, Inderbir; Ukimura, Osamu

    2014-04-01

    We developed and assessed a technique of: (i) expanding Denonvilliers' space by hydrogel (polyethylene glycol) during focal cryoabation; and (ii) temperature mapping to ensure protection of the rectal wall. In a fresh cadaver, 20 cc of hydrogel was injected transperineally into Denonvilliers' space under transrectal ultrasound guidance. Successful expansion of Denonvilliers' space was achieved with a range of 9-11 mm thickness covering the entire posterior prostate surface. Two freeze-thaw cycles were used to expand the iceball reaching the rectal wall as an end-point. Intraoperative transrectal ultrasound monitoring and temperature mapping in Denonvilliers' space by multiple thermocouples documented real-time iceball expansion up to 10 mm beyond the prostate, and safety in protecting the rectal wall from thermal injury. The lowest temperatures of the thermocouples with a distance of 0 mm, 5 mm and 10 mm from the prostate were: -35°C, -18°C and 0°C (P < 0.001), respectively. In gross and microscopic examination, the hydrogel mass measured 11 × 40 × 34 mm, which was identical to the intraoperative transrectal ultrasound measurements, there was no infiltration of the hydrogel into the rectal wall or prostate and no injury to the pelvic organs. In conclusion, the expansion of Denonvilliers' space by transperineal injection of hydrogel is feasible and a promising technique to facilitate energy-based focal therapy of prostate cancer.

  3. Persistent Asymmetric Optic Disc Swelling After Long-Duration Space Flight: Implications for Pathogenesis.

    PubMed

    Mader, Thomas H; Gibson, C Robert; Otto, Christian A; Sargsyan, Ashot E; Miller, Neil R; Subramanian, Prem S; Hart, Stephen F; Lipsky, William; Patel, Nimesh B; Lee, Andrew G

    2017-06-01

    Several ophthalmic findings including optic disc swelling, globe flattening and choroidal folds have been observed in astronauts following long-duration space flight. The authors now report asymmetric choroidal expansion, disc swelling and optic disc morphologic changes in a 45-year-old astronaut which occurred during long-duration space flight and persisted following his space mission. Case study of ocular findings in an astronaut documented during and after a long-duration space flight of approximately 6 months. Before, during and after his spaceflight, he underwent complete eye examination, including fundus photography, ultrasound, and optical coherence tomography. We documented asymmetric choroidal expansion inflight that largely resolved by 30 days postflight, asymmetric disc swelling observed inflight that persisted for over 180 days postflight, asymmetric optic disc morphologic changes documented inflight by OCT that persisted for 630 days postflight and asymmetric globe flattening that began inflight and continued 660 days postflight. Lumbar puncture opening pressures obtained at 7 and 365 days post-mission were 22 and 16 cm H20 respectively. The persistent asymmetric findings noted above, coupled with the lumbar puncture opening pressures, suggest that prolonged microgravity exposure may have produced asymmetric pressure changes within the perioptic subarachnoid space.

  4. Effects of isolation and confinement on humans-implications for manned space explorations.

    PubMed

    Pagel, J I; Choukèr, A

    2016-06-15

    Human psychology and physiology are significantly altered by isolation and confinement. In light of planned exploration class interplanetary missions, the related adverse effects on the human body need to be explored and defined as they have a large impact on a mission's success. Terrestrial space analogs offer an excellent controlled environment to study some of these stressors during a space mission in isolation without the complex environment of the International Space Station. Participants subjected to these space analog conditions can encounter typical symptoms ranging from neurocognitive changes, fatigue, misaligned circadian rhythm, sleep disorders, altered stress hormone levels, and immune modulatory changes. This review focuses on both the psychological and the physiological responses observed in participants of long-duration spaceflight analog studies, such as Mars500 or Antarctic winter-over. They provide important insight into similarities and differences encountered in each simulated setting. The identification of adverse effects from confinement allows not only the crew to better prepare for but also to design feasible countermeasures that will help support space travelers during exploration class missions in the future. Copyright © 2016 the American Physiological Society.

  5. X-rays and neutrons as complementary probes to muons in magnetism: A view from reciprocal space

    NASA Astrophysics Data System (ADS)

    Lander, G. H.

    2000-08-01

    Twenty years ago magnetism and superconductivity appeared mutually exclusive and life was (relatively) simple. The discovery of heavy-fermion superconductivity (1979-1984) and high Tc (1986), changed our perceptions. Gradually, it was realised that either ordered magnetism or magnetic correlations are found in most of these materials. Here I shall concentrate on heavy fermions, in which the f electrons are responsible for the magnetism as well as (probably) the superconductivity. Muons have played a key role in elucidating these the so-called “small moment” systems, such as UPt 3, URu 2Si 2, UPd 2Al 3, etc. Recenty, at the ILL we have measured the low-energy inelastic magnetic signal from UPd 2Al 3 and the response will be compared to the conclusions derived from muon studies. Interestingly, it is accepted wisdom that muons will be sensitive to any small magnetic effects. UBe 13 is fascinating as it has long been the “exception”, with no sign of any magnetism. Now, at Risø National Laboratory, we have found evidence with neutrons for weak magnetic correlations of a most unusual form in UBe 13 - so that it no longer can be regarded as an exception. Neutrons, powerful though they are, are sometimes lost in reciprocal space. U 2Pt 2 In is a non-Fermi liquid, and there is a strong muon anomaly below 10 K, but we have been unable to find the correlations with neutrons. Finally, NpO 2 is one of the oldest “small-moment systems”, and recently muons were able to see an asymmetry below 25 K, and suggested an ordered moment of 0.1μ B. However, the signal has been too small for neutrons. Here I will explain the emergence of a new technique, resonant magnetic X-ray scattering, that, especially in the actinides, has great promise. We have used this at the ESRF to determine the magnetic structure of NpO 2.

  6. Gravity Probe B Gyroscope Rotor

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The Gravity Probe B (GP-B) is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. This photograph is a close up of a niobium-coated gyroscope motor and its housing halves. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Don Harley.)

  7. Gravity Probe B Gyroscope Rotor

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The Gravity Probe B (GP-B) is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. This photograph is a close up of a niobium-coated gyroscope motor and its housing halves. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Don Harley.)

  8. Lessons learned in creating spacecraft computer systems: Implications for using Ada (R) for the space station

    NASA Technical Reports Server (NTRS)

    Tomayko, James E.

    1986-01-01

    Twenty-five years of spacecraft onboard computer development have resulted in a better understanding of the requirements for effective, efficient, and fault tolerant flight computer systems. Lessons from eight flight programs (Gemini, Apollo, Skylab, Shuttle, Mariner, Voyager, and Galileo) and three reserach programs (digital fly-by-wire, STAR, and the Unified Data System) are useful in projecting the computer hardware configuration of the Space Station and the ways in which the Ada programming language will enhance the development of the necessary software. The evolution of hardware technology, fault protection methods, and software architectures used in space flight in order to provide insight into the pending development of such items for the Space Station are reviewed.

  9. Behavioral health in Antarctica: implications for long-duration space missions.

    PubMed

    Lugg, Desmond J

    2005-06-01

    Ideally, evidence from long-duration spaceflight should be used to predict likely occurrences of behavioral health events and for planning management strategies for such events. With small numbers of space travelers, and limited long-duration missions of a year or more, Earth analogues and simulations must be used as the evidence base, despite such analogues lacking microgravity, radiation, rapidly altering photoperiodicity, and fidelity to space. Antarctic health data are reviewed and an assessment made of the likely frequency of behavioral health events. Based on the Antarctic evidence, the likelihood of behavioral health problems in space is low. However, such cases may be serious and of high consequence, placing considerable demands on the mission crew and ground support to achieve a successful outcome, given the availability of pharmaceuticals and resources.

  10. Behavioral health in Antarctica: implications for long-duration space missions

    NASA Technical Reports Server (NTRS)

    Lugg, Desmond J.

    2005-01-01

    Ideally, evidence from long-duration spaceflight should be used to predict likely occurrences of behavioral health events and for planning management strategies for such events. With small numbers of space travelers, and limited long-duration missions of a year or more, Earth analogues and simulations must be used as the evidence base, despite such analogues lacking microgravity, radiation, rapidly altering photoperiodicity, and fidelity to space. Antarctic health data are reviewed and an assessment made of the likely frequency of behavioral health events. Based on the Antarctic evidence, the likelihood of behavioral health problems in space is low. However, such cases may be serious and of high consequence, placing considerable demands on the mission crew and ground support to achieve a successful outcome, given the availability of pharmaceuticals and resources.

  11. Effects of Varying Surface Inclines and Suit Pressure: Implications on Space Suit Design

    NASA Technical Reports Server (NTRS)

    Clowers, Kurt; Clark, Timothy; Harvill, Lauren; Morency, Richard; Rajulu, Sudhakar

    2008-01-01

    Suited human performance studies in reduced gravity environments to date include limited observations from Apollo Lunar surface Extravehicular Activities (EVA) and from previous studies conducted in partial gravity simulation environments. The Constellation Program EVA Systems Project office has initiated tests to develop design requirements for the next generation Lunar EVA suit. Theses studies were conducted in the Space Vehicle Mock-Up Facility (SVMF) at Johnson Space Center from which the results provided recommendations for suit weight, mass, center of gravity, pressure, and suit kinematic constraints that optimize human performance in partial gravity environments.

  12. Sudden emesis following parabolic flight maneuvers Implications for space motion sickness

    NASA Technical Reports Server (NTRS)

    Lackner, J. R.; Graybiel, A.

    1986-01-01

    Episodes of emesis unaccompanied by the usual prodomal signs of motion sickness have been reported by astronauts in the Space Shuttle program. Such reports have raised the issue whether space motion sickness has different characteristics from terrestrial motion sickness. Evidence is presented here from parabolic flight experiments that sudden vomiting can occur in response to a provocative vestibular stimulus even when no premonitory symptoms are being experienced. Accordingly, in chronic exposure conditions, the absence of prominent signs or symptoms of motion sickness does not necessarily mean an absence of sensitization.

  13. Physical and Social Organization of Space in a Combined Credential Programme: Implications for Inclusion

    ERIC Educational Resources Information Center

    Young, Kathryn S.

    2008-01-01

    Social geography brings a new perspective to understanding longstanding separation between general and special education in higher education. This paper uses methods from social geography to consider how the structures and processes of space function to maintain longstanding divisions between general and special education in a US teacher education…

  14. A new method of spatial analysis of irregularly spaced HLB data and biological implications

    USDA-ARS?s Scientific Manuscript database

    Field data on intensity of plant diseases is very often irregularly spaced (i.e., there are varying amounts of distance between rows, ponds, voids, roads, houses, or other land areas). A new method of analysis, sometimes called second-generation wavelet analysis, can be used on this type of irregula...

  15. Space science to the twenty-first century and the technological implications for implementation

    NASA Technical Reports Server (NTRS)

    Herman, D. H.

    1979-01-01

    The paper presents the specific plan for NASA space science missions to the 21st century and highlights the major technological advances that must be effected to accomplish the planned missions. Separate consideration is given to plans for astrophysics, planetary exploration, the solar terrestrial area, and life sciences. The technological consequences of the plans in these separate areas are discussed.

  16. Implications of acceleration environments on scaling materials processing in space to production

    NASA Technical Reports Server (NTRS)

    Demel, Ken

    1990-01-01

    Some considerations regarding materials processing in space are covered from a commercial perspective. Key areas include power, proprietary data, operational requirements (including logistics), and also the center of gravity location, and control of that location with respect to materials processing payloads.

  17. Implications of Outside-the-Box Technologies on Future Space Exploration and Colonization

    NASA Astrophysics Data System (ADS)

    Loder, Theodore C.

    2003-01-01

    In general, planning for future manned space exploration either to the moon, Mars, or an asteroid has depended on a somewhat linear extrapolation of our present technologies. Two major prohibitive cost issues regarding such planning are payload lift and in-flight energy generation. The costs of these in both engineering and actual flight costs, coupled with the planning necessary to carry out such exploration have prevented us from actively moving forward. Although, it will be worthwhile to continue to plan for such exploration using ``present'' technologies, I recommend that planning be concerned mainly with mission strategies and goals utilizing both present technology and totally new energy breakthroughs. There are presently in research and development an entire suite of relevant outside-the-box technologies which will include both zero point energy generation and antigravity technologies that will replace our present solar/nuclear/fuel cell energy technologies and liquid/solid fuel rockets. This paper describes some of these technologies, the physics behind them and their potential use for manned space exploration. The companies and countries that first incorporate these technologies into their space programs will lead the way in exploring and colonizing space.

  18. Response of Silicon-Based Linear Energy Transfer Spectrometers: Implication for Radiation Risk Assessment in Space Flights

    NASA Technical Reports Server (NTRS)

    Badhwar, G. D.; O'Neill, P. M.

    2001-01-01

    There is considerable interest in developing silicon-based telescopes because of their compactness and low power requirements. Three such telescopes have been flown on board the Space Shuttle to measure the linear energy transfer spectra of trapped, galactic cosmic ray, and solar energetic particles. Dosimeters based on single silicon detectors have also been flown on the Mir orbital station. A comparison of the absorbed dose and radiation quality factors calculated from these telescopes with that estimated from measurements made with a tissue equivalent proportional counter show differences which need to be fully understood if these telescopes are to be used for astronaut radiation risk assessments. Instrument performance is complicated by a variety of factors. A Monte Carlo-based technique was developed to model the behavior of both single element detectors in a proton beam, and the performance of a two-element, wide-angle telescope, in the trapped belt proton field inside the Space Shuttle. The technique is based on: (1) radiation transport intranuclear-evaporation model that takes into account the charge and angular distribution of target fragments, (2) Landau-Vavilov distribution of energy deposition allowing for electron escape, (3) true detector geometry of the telescope, (4) coincidence and discriminator settings, (5) spacecraft shielding geometry, and (6) the external space radiation environment, including albedo protons. The value of such detailed modeling and its implications in astronaut risk assessment is addressed. c2001 Elsevier Science B.V. All rights reserved.

  19. Response of silicon-based linear energy transfer spectrometers: implication for radiation risk assessment in space flights.

    PubMed

    Badhwar, G D; O'Neill, P M

    2001-07-11

    There is considerable interest in developing silicon-based telescopes because of their compactness and low power requirements. Three such telescopes have been flown on board the Space Shuttle to measure the linear energy transfer spectra of trapped, galactic cosmic ray, and solar energetic particles. Dosimeters based on single silicon detectors have also been flown on the Mir orbital station. A comparison of the absorbed dose and radiation quality factors calculated from these telescopes with that estimated from measurements made with a tissue equivalent proportional counter show differences which need to be fully understood if these telescopes are to be used for astronaut radiation risk assessments. Instrument performance is complicated by a variety of factors. A Monte Carlo-based technique was developed to model the behavior of both single element detectors in a proton beam, and the performance of a two-element, wide-angle telescope, in the trapped belt proton field inside the Space Shuttle. The technique is based on: (1) radiation transport intranuclear-evaporation model that takes into account the charge and angular distribution of target fragments, (2) Landau-Vavilov distribution of energy deposition allowing for electron escape, (3) true detector geometry of the telescope, (4) coincidence and discriminator settings, (5) spacecraft shielding geometry, and (6) the external space radiation environment, including albedo protons. The value of such detailed modeling and its implications in astronaut risk assessment is addressed.

  20. Response of Silicon-Based Linear Energy Transfer Spectrometers: Implication for Radiation Risk Assessment in Space Flights

    NASA Technical Reports Server (NTRS)

    Badhwar, G. D.; O'Neill, P. M.

    2001-01-01

    There is considerable interest in developing silicon-based telescopes because of their compactness and low power requirements. Three such telescopes have been flown on board the Space Shuttle to measure the linear energy transfer spectra of trapped, galactic cosmic ray, and solar energetic particles. Dosimeters based on single silicon detectors have also been flown on the Mir orbital station. A comparison of the absorbed dose and radiation quality factors calculated from these telescopes with that estimated from measurements made with a tissue equivalent proportional counter show differences which need to be fully understood if these telescopes are to be used for astronaut radiation risk assessments. Instrument performance is complicated by a variety of factors. A Monte Carlo-based technique was developed to model the behavior of both single element detectors in a proton beam, and the performance of a two-element, wide-angle telescope, in the trapped belt proton field inside the Space Shuttle. The technique is based on: (1) radiation transport intranuclear-evaporation model that takes into account the charge and angular distribution of target fragments, (2) Landau-Vavilov distribution of energy deposition allowing for electron escape, (3) true detector geometry of the telescope, (4) coincidence and discriminator settings, (5) spacecraft shielding geometry, and (6) the external space radiation environment, including albedo protons. The value of such detailed modeling and its implications in astronaut risk assessment is addressed. c2001 Elsevier Science B.V. All rights reserved.

  1. VANDENBERG AFB, CALIF. - A worker in the NASA spacecraft processing facility on North Vandenberg Air Force Base adjust the supports on a solar array panel to be lifted and installed on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-03

    VANDENBERG AFB, CALIF. - A worker in the NASA spacecraft processing facility on North Vandenberg Air Force Base adjust the supports on a solar array panel to be lifted and installed on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  2. VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, Dr. Francis Everitt, principal investigator, and Brad Parkinson, co-principal investigator, both from Stanford University, hold one of the small gyroscopes used in the Gravity Probe B spacecraft. The GP-B towers behind them. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-10

    VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, Dr. Francis Everitt, principal investigator, and Brad Parkinson, co-principal investigator, both from Stanford University, hold one of the small gyroscopes used in the Gravity Probe B spacecraft. The GP-B towers behind them. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  3. VANDENBERG AFB, CALIF. - Workers in the NASA spacecraft processing facility on North Vandenberg Air Force Base work on a solar array panel to be installed on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-03

    VANDENBERG AFB, CALIF. - Workers in the NASA spacecraft processing facility on North Vandenberg Air Force Base work on a solar array panel to be installed on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  4. VANDENBERG AFB, CALIF. - Workers in the NASA spacecraft processing facility on North Vandenberg Air Force Base attach supports to a solar array panel to be lifted and installed on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-03

    VANDENBERG AFB, CALIF. - Workers in the NASA spacecraft processing facility on North Vandenberg Air Force Base attach supports to a solar array panel to be lifted and installed on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  5. VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, the Gravity Probe B spacecraft is seen with two solar array panels installed. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-04

    VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, the Gravity Probe B spacecraft is seen with two solar array panels installed. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  6. VANDENBERG AFB, CALIF. - Workers in the NASA spacecraft processing facility on North Vandenberg Air Force Base prepare to rotate the framework containing one of four solar panels to be installed on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-03

    VANDENBERG AFB, CALIF. - Workers in the NASA spacecraft processing facility on North Vandenberg Air Force Base prepare to rotate the framework containing one of four solar panels to be installed on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  7. VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, the Gravity Probe B spacecraft is seen with all four solar array panels installed. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-04

    VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, the Gravity Probe B spacecraft is seen with all four solar array panels installed. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  8. VANDENBERG AFB, CALIF. - Workers in the NASA spacecraft processing facility on North Vandenberg Air Force Base attach a solar array panel on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-03

    VANDENBERG AFB, CALIF. - Workers in the NASA spacecraft processing facility on North Vandenberg Air Force Base attach a solar array panel on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  9. VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, a balloon gently lifts the solar array panel to be installed on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-04

    VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, a balloon gently lifts the solar array panel to be installed on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  10. VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, workers prepare to attach the top of a solar array panel onto the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-04

    VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, workers prepare to attach the top of a solar array panel onto the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  11. VANDENBERG AFB, CALIF. - Workers in the NASA spacecraft processing facility on North Vandenberg Air Force Base prepare for the installation of solar array panel 3 on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-03

    VANDENBERG AFB, CALIF. - Workers in the NASA spacecraft processing facility on North Vandenberg Air Force Base prepare for the installation of solar array panel 3 on the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  12. VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, a worker checks the installation of a solar array panel onto the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

    NASA Image and Video Library

    2003-11-04

    VANDENBERG AFB, CALIF. - In the NASA spacecraft processing facility on North Vandenberg Air Force Base, a worker checks the installation of a solar array panel onto the Gravity Probe B spacecraft. Installing each array is a 3-day process and includes a functional deployment test. The Gravity Probe B mission is a relativity experiment developed by NASA’s Marshall Space Flight Center, Stanford University and Lockheed Martin. The spacecraft will test two extraordinary predictions of Albert Einstein’s general theory of relativity that he advanced in 1916: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Gravity Probe B consists of four sophisticated gyroscopes that will provide an almost perfect space-time reference system. The mission will look in a precision manner for tiny changes in the direction of spin.

  13. Inflatable traversing probe seal

    NASA Technical Reports Server (NTRS)

    Trimarchi, Paul A.

    1991-01-01

    An inflatable seal acts as a pressure-tight zipper to provide traversing capability for instrumentation rakes and probes. A specially designed probe segment with a teardrop cross-section in the vicinity of the inflatable seal minimizes leakage at the interface. The probe is able to travel through a lengthwise slot in a pressure vessel or wind tunnel section, while still maintaining pressure integrity. The design uses two commercially available inflatable seals, opposing each other, to cover the probe slot in a wind tunnel wall. Proof-of-concept tests were conducted at vessel pressures up to 30 psig, with seals inflated to 50 psig, showing no measurable leakage along the seal's length or around the probe teardrop cross-section. This seal concept can replace the existing technology of sliding face plate/O-ring systems in applications where lengthwise space is limited.

  14. Determination of the solution-bound conformation of an amino acid binding protein by NMR paramagnetic relaxation enhancement: use of a single flexible paramagnetic probe with improved estimation of its sampling space.

    PubMed

    Bermejo, Guillermo A; Strub, Marie-Paule; Ho, Chien; Tjandra, Nico

    2009-07-15

    We demonstrate the feasibility of elucidating the bound ("closed") conformation of a periplasmic binding protein, the glutamine-binding protein (GlnBP), in solution, using paramagnetic relaxation enhancements (PREs) arising from a single paramagnetic group. GlnBP consists of two globular domains connected by a hinge. Using the ligand-free ("open") conformation as a starting point, conjoined rigid-body/torsion-angle simulated annealing calculations were performed using backbone (1)H(N)-PREs as a major source of distance information. Paramagnetic probe flexibility was accounted for via a multiple-conformer representation. A conventional approach where the entire PRE data set is enforced at once during simulated annealing yielded poor results due to inappropriate conformational sampling of the probe. On the other hand, significant improvements in coordinate accuracy were obtained by estimating the probe sampling space prior to structure calculation. Such sampling is achieved by refining the ensemble of probe conformers with intradomain PREs only, keeping the protein backbone fixed in the open form. Subsequently, while constraining the probe to the previously found conformations, the domains are allowed to move relative to each other under the influence of the non-intradomain PREs, giving the hinge region torsional degrees of freedom. Thus, by partitioning the protocol into "probe sampling" and "backbone sampling" stages, structures significantly closer to the X-ray structure of ligand-bound GlnBP were obtained.

  15. Some Thoughts on the Implications of Faster-Than-Light Interstellar Space Travel

    NASA Astrophysics Data System (ADS)

    Crawford, I. A.

    1995-09-01

    There are reasons for believing that faster-than-light (FTL) interstellar space travel may be consistent with the laws of physics, and a brief review of various FTL travel concepts is presented. It is argued that FTL travel would revolutionise the scientific exploration of the Universe, but would only significantly shorten the Galactic colonisation timescale from the 106 years estimated on the assumption of sub-light interstellar travel if the mass-production of FTL space vehicles proves to be practical. FTL travel would permit the development of interstellar social and political institutions which would probably be impossible otherwise, and may therefore strengthen the 'zoo hypothesis' as an explanation for the apparent absence of extraterrestrial beings in the Solar System.

  16. The properties of high-dimensional data spaces: implications for exploring gene and protein expression data

    PubMed Central

    Clarke, Robert; Ressom, Habtom W.; Wang, Antai; Xuan, Jianhua; Liu, Minetta C.; Gehan, Edmund A.; Wang, Yue

    2007-01-01

    High-throughput genomic and proteomic technologies are widely used in cancer research to build better predictive models of diagnosis, prognosis and therapy, to identify and characterize key signalling networks and to find new targets for drug development. These technologies present investigators with the task of extracting meaningful statistical and biological information from high-dimensional data spaces, wherein each sample is defined by hundreds or thousands of measurements, usually concurrently obtained. The properties of high dimensionality are often poorly understood or overlooked in data modelling and analysis. From the perspective of translational science, this Review discusses the properties of high-dimensional data spaces that arise in genomic and proteomic studies and the challenges they can pose for data analysis and interpretation. PMID:18097463

  17. Implications for space radiation environment models from CREAM & CREDO measurements over half a solar cycle.

    PubMed

    Dyer, C S; Truscott, P R; Peerless, C L; Watson, C J; Evans, H E; Knight, P; Cosby, M; Underwood, C; Cousins, T; Noulty, R; Maag, C

    1999-10-01

    Flight data obtained between 1990 and 1997 from the Cosmic Radiation Environment Monitors CREAM & CREDO carried on UoSAT-3, Space Shuttle, STRV-1a (Space Technology Research Vehicle) and APEX (Advanced Photovoltaic and Electronics Experiment Spacecraft) provide coverage over half a solar cycle. The modulation of cosmic rays and evolution of the South Atlantic Anomaly are observed, the former comprising a factor of three increase at high latitudes and the latter a general increase accompanied by a north-westward drift. Comparison of particle fluxes and linear energy transfer (LET) spectra is made with improved environment & radiation transport calculations which account for shield distributions and secondary particles. While there is an encouraging convergence between predictions and observations, significant improvements are still required, particularly in the treatment of locally produced secondary particles. Solar-particle events during this time period have LET spectra significantly below the October 1989 event which has been proposed as a worst case model.

  18. Transcriptome analyses of Arabidopsis thaliana seedlings grown in space: implications for gravity-responsive genes.

    PubMed

    Correll, Melanie J; Pyle, Tyler P; Millar, Katherine D L; Sun, Yijun; Yao, Jin; Edelmann, Richard E; Kiss, John Z

    2013-09-01

    The transcriptome of seedlings was analyzed from experiments performed on the International Space Station to study the interacting effects of light and gravity on plant tropisms (project named TROPI-2; Kiss et al. 2012). Seeds of Arabidopsis were germinated in space, and seedlings were then grown in the European Modular Cultivation System for 4 days at ~1g followed by exposure to a range of gravitational accelerations (from microgravity to 1g) and two light treatments (blue light with or without a 1 h pretreatment with red). At the end of the experiments, the cassettes containing the seedlings were frozen in the minus eighty laboratory freezer and returned to Earth on space shuttle mission STS-131. The RNA was extracted from whole seedlings and used for the transcriptome analyses. A comparison of 1g spaceflight samples with 1g ground controls identified 230 genes that were differentially regulated at least twofold, emphasizing the need for "in situ" tissue fixation on a 1g centrifuge as an important control for spaceflight experiments. A further comparison of all spaceflight samples with ground controls identified approximately 280 genes that were differentially regulated at least twofold. Of these genes, several were involved in regulating cell polarity (i.e., auxin, calcium, lipid metabolism), cell-wall development, oxygen status, and cell defense or stress. However, when the transcriptome of the all g-treated spaceflight samples was compared with microgravity samples, only ~130 genes were identified as being differently regulated (P ≤ 0.01). Of this subset, only 27 genes were at least twofold differently regulated between microgravity and 1g space samples and included putative/pseudo/undefined genes (14), transposable elements (5), an expansin (ATEXP24; At1g21240), a cell-wall kinase (WAK3; At1g21240), a laccase-like flavonoid oxidase (TT10; At5g48100), among others.

  19. Space Shuttle Main Engine Implications for the Abort-to-Orbit Off-the-Pad Study

    NASA Technical Reports Server (NTRS)

    Schoffstoll, Dayna L.

    2003-01-01

    In 2001, the Space Shuttle Main Engine (SSME) project office was contacted by the Space Shuttle Ascent Guidance, Navigation, and Control group to provide the engine perspective for an Abort-to-Orbit (ATO) study. The purpose of the AT0 Off-the-Pad study was to determine the feasibility of eliminating the Return to Launch Site and Transatlantic abort modes by using a five-segment solid rocket booster and throttling the remaining SSMEs to a higher power level. This would enable all abort modes to be Abort-to-Orbit. The SSME project office at Marshall Space Flight Center collaborated with MSFC's Space Transportation Directorate and Rocketdyne Propulsion and Power to provide the AT0 Off-the-Pad study with the analysis required. Power levels at 109%, 1 11% and 1 13% of rated power level were studied as well as mixture ratio decreases down to 5.85. SSME was to evaluate and define the technical and programmatic impacts to certify the SSME to these abort power levels. The SSME systems analysis group performed a steady state analysis using the SSME power balance model to determine if there were any technical issues associated with higher power level, low mixture ratio operation. Based on each power level/mixture ratio combination, an engine certification plan was created and a preliminary probabilistic risk assessment was performed. The results showed favorable results for higher power 1evel/lower mixture ratio SSME operation. In nearly all performance and redline parameters, the traded engine operation was encompassed by nominal engine performance of a prior engine configuration.

  20. Assessment of Galactic Cosmic Ray Models and Implications on the Estimation of Radiation Exposure in Space

    NASA Astrophysics Data System (ADS)

    Mrigakshi, A. I.; Matthiä, D.; Berger, T.; Reitz, G.; Wimmer-Schweingruber, R. F.

    2012-12-01

    Astronauts are subjected to elevated levels of high-energy ionizing radiation in space which poses a substantial risk to their health. Therefore, the assessment of the radiation exposure for long duration manned spaceflight is essential. This is done by measuring dose using various detector techniques and by performing numerical simulations utilizing radiation transport codes which allow to predict radiation exposure for future missions and for conditions where measurements are not feasible or available. A necessary prerequisite for an accurate estimation of the exposure using the latter approach is a reliable description of the radiation spectra. Accordingly, in order to estimate the exposure from the Galactic Cosmic Rays (GCRs), which are one of the major sources of radiation exposure in space, GCR models are required. This work presents an evaluation of GCR models for dosimetry purposes and the effect of applying these models on the estimation of GCR exposure in space outside and inside the Earth's magnetosphere. To achieve this, widely used GCR models - Badhwar-O'Neill2010, Burger-Usoskin, CREME2009 and CREME96, were evaluated by comparing model spectra for light and heavy nuclei with measurements from various high-altitude balloon and space missions over several decades. Additionally a new model, based on the GCR-ISO model, developed at the German Aerospace Centre (DLR) was also investigated. The differences arising in the radiation exposure by applying these models are quantified in terms of absorbed dose and dose equivalent rates that were estimated numerically using the GEANT4 Monte-Carlo framework. During certain epochs in the last decade, there are large discrepancies between the model and the measured spectra. All models exhibit weaknesses in describing the increased GCR flux that was observed in 2009-2010. The differences in the spectra, described by the models, result in considerable differences in the estimated dose quantities.

  1. Commercial Eyes in Space: Implications for U.S. Military Operations in 2030

    DTIC Science & Technology

    2008-03-01

    techniques could provide valuable sources of information. Differential LIDAR is a technique used by airborne systems today where multiple laser ... laser technologies will be required effectively implement commercial space-based LIDAR for specific niche markets. If the challenges can be...type of radar that takes advantage of the sensor’s movement to create a more detailed image. LIDAR emits light or lasers of specific wavelengths

  2. High Voltage Solar Concentrator Experiment with Implications for Future Space Missions

    NASA Technical Reports Server (NTRS)

    Mehdi, Ishaque S.; George, Patrick J.; O'Neill, Mark; Matson, Robert; Brockschmidt, Arthur

    2004-01-01

    This paper describes the design, development, fabrication, and test of a high performance, high voltage solar concentrator array. This assembly is believed to be the first ever terrestrial triple-junction-cell solar array rated at over 1 kW. The concentrator provides over 200 W/square meter power output at a nominal 600 Vdc while operating under terrestrial sunlight. Space-quality materials and fabrication techniques were used for the array, and the 3005 meter elevation installation below the Tropic of Cancer allowed testing as close as possible to space deployment without an actual launch. The array includes two concentrator modules, each with a 3 square meter aperture area. Each concentrator module uses a linear Fresnel lens to focus sunlight onto a photovoltaic receiver that uses 240 series-connected triple-junction solar cells. Operation of the two receivers in series can provide 1200 Vdc which would be adequate for the 'direct drive' of some ion engines or microwave transmitters in space. Lens aperture width is 84 cm and the cell active width is 3.2 cm, corresponding to a geometric concentration ratio of 26X. The evaluation includes the concentrator modules, the solar cells, and the materials and techniques used to attach the solar cells to the receiver heat sink. For terrestrial applications, a finned aluminum extrusion was used for the heat sink for the solar cells, maintaining a low cell temperature so that solar cell efficiency remains high.

  3. High Voltage Solar Concentrator Experiment with Implications for Future Space Missions - S6a-35

    NASA Astrophysics Data System (ADS)

    George, I. S. Mehdi P. J.; O'Neill, M.; Matson, R.; Borckschmidt, A.

    2004-12-01

    This paper describes the design, development, fabrication, and test of a high performance, high voltage solar concentrator array. This assembly is believed to be the first ever terrestrial triple-junction-cell solar array rated at over 1 kW. The concentrator provides over 200 W/square meter power output at a nominal 600 Vdc while operating under terrestrial sunlight. Space-quality materials and fabrication techniques were used for the array, and the 3005-meter elevation installation below the Tropic of Cancer allowed testing as close as possible to space deployment without an actual launch. The array includes two concentrator modules, each with a 3 square meter aperture area. Each concentrator module uses a linear Fresnel lens to focus sunlight onto a photovoltaic receiver that uses 240 series-connected triple-junction solar cells. Operation of the two receivers in series can provide 1200 Vdc which would be adequate for the "direct drive" of some ion engines or microwave transmitters in space. Lens aperture width is 84 cm and the cell active width is 3.2 cm, corresponding to a geometric concentration ratio of 26X. The evaluation includes the concentrator modules, the solar cells, and the materials and techniques used to attach the solar cells to the receiver heat sink. For terrestrial applications, a finned aluminum extrusion was used for the heat sink for the solar cells, maintaining a low cell temperature so that solar cell efficiency remains high.

  4. Voluntary immunomodulation: potentiality and implications for long-duration manned space-flights

    NASA Astrophysics Data System (ADS)

    Geuna, Stefano

    The influence of psychological and neural factors on immunologic activity has been dedicated a growing interest over the past fifteen years, since the publication ofPsychoneuroimmunology by Robert Ader in 1981. Studies on this topic gave evidence for bi-directional communication between psychosocial, behavioural, neuroanatomical and neuroendocrine processes with the immune system and the detrimental effects of various stressors, physical and psychological, on immune reactions were widely investigated with reports of stress-induced changes in immune paramenters and immunocompetence. Much of the evidence support the notion that stress is associated with an increase in those diseases against which the immune system defends. Recently, several studies showed that immune functions can be influenced voluntarily and the term voluntary immunomodulation was coined to describe the use of various hypnosis-like and relaxation/imagery techniques for the self-regulation of immune activity. Alterations in the immune regulatory system are one of the most critical issues to be addressed in relation to crew health management during space missions, especially long-term ones. Providing crewmembers with a tool to enhance immunocompetence might be of great value to defend against some severe diseases, such as cancer and infectious illness, which may be elicited in outer space. In this view, a critical assessment of the potential usefulness of voluntary immunomodulation for crew health maintenance during manned space-flight is presented and discussed.

  5. Methodological and technological implications of quantitative human movement analysis in long term space flights.

    PubMed

    Ferrigno, G; Baroni, G; Pedotti, A

    1999-04-01

    In the frame of the 179-days EUROMIR '95 space mission, two in-flight experiments foresaw the analysis of three-dimensional human movements in microgravity. For this aim, a space qualified opto-electronic motion analyser based on passive markers was installed onboard the MIR Space Station. The paper describes the experimental procedures designed in order to face technical and operational limitations imposed by the critical environment of the orbital module. The reliability of the performed analysis is discussed, focusing two related aspects: accuracy in three-dimensional marker localisation and data comparability among different experimental sessions. The effect of the critical experimental set-up and of TV cameras optical distortions is evaluated on in-flight acquired data, by performing an analysis on Euclidean distance conservation on rigid bodies. An optimisation method for the recovering of a unique reference frame throughout the whole mission is described. Results highlight the potentiality that opto-electronics and close-range photogrammetry have for automatic motion analysis onboard orbital modules. The discussion of the obtained results provides general suggestions for the implementation of experimental human movement analysis in critical environments, based on the suitable trade-off between external constraints and achievable analysis reliability.

  6. Expert systems, security and quality assurance: implications of patient records as data-space.

    PubMed

    Kluge, E H

    2001-01-01

    The concept of data-space is fruitful in trying to understand the ethical rights and duties that surround the treatment of patient records. However, it also provides a solution to three apparently unconnected problems: the construction of expert diagnostic systems, the development of an internal security element within the sphere of permitted data-access for health care professionals, and the development of a professional quality assurance mechanism. This paper presents a model of how these diverse aims may be achieved. It does so by developing the notion of the logical form of data within a data-space and by showing how the path taken by a health care professional through a profession-relative data-space can provide checks for the security, quality and appropriateness of the path itself. The result is important in that it provides an integrated method for information specialists to meet their fiduciary obligations towards the patients whose records are in their care, and towards the institutions that employ them.

  7. Adaptive changes of rhythmic EEG oscillations in space implications for brain-machine interface applications.

    PubMed

    Cheron, G; Cebolla, A M; Petieau, M; Bengoetxea, A; Palmero-Soler, E; Leroy, A; Dan, B

    2009-01-01

    The dramatic development of brain machine interfaces has enhanced the use of human brain signals conveying mental action for controlling external actuators. This chapter will outline current evidences that the rhythmic electroencephalographic activity of the brain is sensitive to microgravity environment. Experiments performed in the International Space Station have shown significant changes in the power of the astronauts' alpha and mu oscillations in resting condition, and other adaptive modifications in the beta and gamma frequency range during the immersion in virtual navigation. In this context, the dynamic aspects of the resting or default condition of the awaken brain, the influence of the "top-down" dynamics, and the possibility to use a more constrained configuration by a new somatosensory-evoked potential (gating approach) are discussed in the sense of future uses of brain computing interface in space mission. Although, the state of the art of the noninvasive BCI approach clearly demonstrates their ability and the great expectance in the field of rehabilitation for the restoration of defective communication between the brain and external world, their future application in space mission urgently needs a better understanding of brain neurophysiology, in particular in aspects related to neural network rhythmicity in microgravity.

  8. Investigation of outer planet atmospheres using the pioneer entry probe radio system

    NASA Technical Reports Server (NTRS)

    Croft, T. A.

    1974-01-01

    The requirements for a telecommunication link which will relay information from a space probe to a carrier spacecraft during space exploration missions are examined. Specific experiments are described and the relative value of the proposed techniques are evaluated. Radio science methods as related to telecommunications systems are discussed. Operational implications of the various approaches to scientific measurement by telemetry of tracking radios are analyzed. Emphasis is placed on a conceptual description of the physics rather than the mathematical development.

  9. Probing the space-time geometry around black hole candidates with the resonance models for high-frequency QPOs and comparison with the continuum-fitting method

    SciTech Connect

    Bambi, Cosimo

    2012-09-01

    Astrophysical black hole candidates are thought to be the Kerr black hole predicted by General Relativity. However, in order to confirm the Kerr-nature of these objects, we need to probe the geometry of the space-time around them and check that observations are consistent with the predictions of the Kerr metric. That can be achieved, for instance, by studying the properties of the electromagnetic radiation emitted by the gas in the accretion disk. The high-frequency quasi-periodic oscillations observed in the X-ray flux of some stellar-mass black hole candidates might do the job. As the frequencies of these oscillations depend only very weakly on the observed X-ray flux, it is thought they are mainly determined by the metric of the space-time. In this paper, I consider the resonance models proposed by Abramowicz and Kluzniak and I extend previous results to the case of non-Kerr space-times. The emerging picture is more complicated than the one around a Kerr black hole and there is a larger number of possible combinations between different modes. I then compare the bounds inferred from the twin peak high-frequency quasi-periodic oscillations observed in three micro-quasars (GRO J1655-40, XTE J1550-564, and GRS 1915+105) with the measurements from the continuum-fitting method of the same objects. For Kerr black holes, the two approaches do not provide consistent results. In a non-Kerr geometry, this conflict may be solved if the observed quasi-periodic oscillations are produced by the resonance ν{sub θ}:ν{sub r} = 3:1, where ν{sub θ} and ν{sub r} are the two epicyclic frequencies. It is at least worth mentioning that the deformation from the Kerr solution required by observations would be consistent with the one suggested in another recent work discussing the possibility that steady jets are powered by the spin of these compact objects.

  10. A modified method for locating parapharyngeal space neoplasms on magnetic resonance images: implications for differential diagnosis

    PubMed Central

    Liu, Xue-Wen; Wang, Ling; Li, Hui; Zhang, Rong; Geng, Zhi-Jun; Wang, De-Ling; Xie, Chuan-Miao

    2014-01-01

    The parapharyngeal space (PPS) is an inverted pyramid-shaped deep space in the head and neck region, and a variety of tumors, such as salivary gland tumors, neurogenic tumors, nasopharyngeal carcinomas with parapharyngeal invasion, and lymphomas, can be found in this space. The differential diagnosis of PPS tumors remains challenging for radiologists. This study aimed to develop and test a modified method for locating PPS tumors on magnetic resonance (MR) images to improve preoperative differential diagnosis. The new protocol divided the PPS into three compartments: a prestyloid compartment, the carotid sheath, and the areas outside the carotid sheath. PPS tumors were located in these compartments according to the displacements of the tensor veli palatini muscle and the styloid process, with or without blood vessel separations and medial pterygoid invasion. This protocol, as well as a more conventional protocol that is based on displacements of the internal carotid artery (ICA), was used to assess MR images captured from a series of 58 PPS tumors. The consequent distributions of PPS tumor locations determined by both methods were compared. Of all 58 tumors, our new method determined that 57 could be assigned to precise PPS compartments. Nearly all (13/14; 93%) tumors that were located in the pre-styloid compartment were salivary gland tumors. All 15 tumors within the carotid sheath were neurogenic tumors. The vast majority (18/20; 90%) of trans-spatial lesions were malignancies. However, according to the ICA-based method, 28 tumors were located in the pre-styloid compartment, and 24 were located in the post-styloid compartment, leaving 6 tumors that were difficult to locate. Lesions located in both the pre-styloid and the post-styloid compartments comprised various types of tumors. Compared with the conventional ICA-based method, our new method can help radiologists to narrow the differential diagnosis of PPS tumors to specific compartments. PMID:25104280

  11. The Bellagio Report: Cardiovascular risks of spaceflight: implications for the future of space travel.

    PubMed

    Sides, Marian B; Vernikos, Joan; Convertino, Victor A; Stepanek, Jan; Tripp, Lloyd D; Draeger, Jorg; Hargens, Alan R; Kourtidou-Papadeli, Chrysoula; Pavy-LeTraon, Anne; Russomano, Thais; Wong, Julielynn Y; Buccello, Regina R; Lee, Peter H; Nangalia, Vishal; Saary, M Joan

    2005-09-01

    Long-duration space missions, as well as emerging civilian tourist space travel activities, prompted review and assessment of data available to date focusing on cardiovascular risk and available risk mitigation strategies. The goal was the creation of tools for risk priority assessments taking into account the probability of the occurrence of an adverse cardiovascular event and available and published literature from spaceflight data as well as available risk mitigation strategies. An international group of scientists convened in Bellagio, Italy, in 2004 under the auspices of the Aerospace Medical Association to review available literature for cardiac risks identified in the Bioastronautics Critical Path Roadmap (versions 2000, 2004). This effort led to the creation of a priority assessment framework to allow for an objective assessment of the hazard, probability of its occurrence, mission impact, and available risk mitigation measures. Spaceflight data are presented regarding evidence/ no evidence of cardiac dysrhythmias, cardiovascular disease, and cardiac function as well as orthostatic intolerance, exercise capacity, and peripheral resistance in presyncopal astronauts compared to non-presyncopal astronauts. Assessment of the priority of different countermeasures was achieved with a tabular framework with focus on probability of occurrence, mission impact, compliance, practicality, and effectiveness of countermeasures. Special operational settings and circumstances related to sensitive portions of any mission and the impact of environmental influences on mission effectiveness are addressed. The need for development of diagnostic tools, techniques, and countermeasure devices, food preparation, preservation technologies and medication, as well as an infrastructure to support these operations are stressed. Selected countermeasure options, including artificial gravity and pharmacological countermeasures need to be systematically evaluated and validated in flight

  12. Food predictability determines space use of endangered vultures: implications for management of supplementary feeding.

    PubMed

    López-López, Pascual; García-Ripollés, Clara; Urios, Vicente

    2014-07-01

    Understanding space use of free-living endangered animals is key to informing management decisions for conservation planning. Like most scavengers, vultures have evolved under a context of unpredictability of food resources (i.e., exploiting scattered carcasses that are intermittently available). However, the role of predictable sources of food in shaping spatial ecology of vultures has seldom been studied in detail. Here, we quantify the home range of the Egyptian Vulture (Neophron percnopterus), a long-lived raptor that has experienced severe population decline throughout its range and is qualified as endangered worldwide. To this end, six adults were tracked by satellite telemetry in Spain during the breeding season, from 2007 to 2012, recording 10360 GPS locations. Using Resource Utilization Functions, we assessed the topology of the Utilization Distribution, a three-dimensional measure that shows the probability of finding an animal within the home range. Our results showed how food availability, and principally, how food predictability, determines ranging behavior of this species. Egyptian Vultures showed consistent site fidelity across years, measured as the two- and three-dimensional overlap in their home ranges. Space use varied considerably within the home range and remarkably, places located far from nesting sites were used more frequently than some areas located closer. Therefore, traditional conservation measures based on establishing restrictive rules within a fixed radius around nesting sites could be biologically meaningless if other areas within the home range are not protected too. Finally, our results emphasize the importance of anthropogenic predictable sources of food (mainly vulture restaurants) in shaping the space use of scavengers, which is in agreement with recent findings. Hence, measures aimed at ensuring food availability are essential to preserve this endangered vulture, especially in the present context of limiting carrion dumping in

  13. Spectrofluorometric analysis of amino acid mixtures: Implications for future space missions

    NASA Astrophysics Data System (ADS)

    Chan, Hoi S.; Martins, Zita; Sephton, Mark A.

    2012-01-01

    Efficient detection of organic molecules is fundamental for the success of future life detection missions. Spectrofluorometric analysis is one of the many techniques that may be used to detect organic molecules in extraterrestrial settings. A particularly important class of organic molecules to target is the amino acids on which all terrestrial life depends. This study aims to identify the optimum fluorescence excitation and emission wavelengths for 17 amino acid standards to examine the effects of amino acid concentrations, mixtures and fluorescence quenching. The results and interpretations can guide the design and operation of life detection protocols on future space missions.

  14. The Explosion of Commercial Space and the Implications for National Security

    DTIC Science & Technology

    1999-01-01

    space as an approach to this di­ lemma. On the one hand, commer ciali za tion is not a total panacea. To be sure, some functions are not ame na ble to...com mer ciali za tion, such as mis sile warning, signals intel li gence, certain sur veil lance functions inte grated into weapon sys tems, heroi...commer ciali za tion of launch is inexo ra ble. Conse quently, I think that the Air Force will follow NASA’s lead and ul ti mately purchase launch as

  15. Active Probing of Space Plasmas

    DTIC Science & Technology

    1989-09-01

    TERMS (Continue on reverse it necessary and identify by block number) FIELUP SUB-G RU Elcrnacceleration’ -,pccatinteractions. I Wave particle interaction...of a Conductinig Bodyi, Geophys, Res. Lett., 1-4, 1170 (1987). 13. M.A. Morgan, C Chan, D.L. Cooke, and M.F. Tnutz, The Dynamics of Charged Particles ...value of the incident frequenCy. Calculations or, single particle acceleration show that initially cold electrons can galin I or 2 keY for moderate

  16. Implications of the Next Generation Science Standards for Earth and Space Sciences

    NASA Astrophysics Data System (ADS)

    Wysession, M. E.; Colson, M.; Duschl, R. A.; Huff, K.; Lopez, R. E.; Messina, P.; Speranza, P.; Matthews, T.; Childress, J.

    2012-12-01

    The Next Generation Science Standards (NGSS), due to be released in 2013, set a new direction for K-12 science education in America. These standards will put forth significant changes for Earth and space sciences. The NGSS are based upon the recommendations of the National Research Council's 2011 report "A Framework for K-12 Science Education: Practices, Cross-Cutting Concepts, and Core Ideas." The standards are being written by a large group of authors who represent many different constituencies, including 26 participating states, in a process led by Achieve, Inc. The standards encourage innovative ways to teach science at the K-12 level, including enhanced integration between the content, practices, and crosscutting ideas of science and greater assimilation among the sciences and engineering, and among the sciences, mathematics, and English language arts. The NGSS presents a greater emphasis on Earth and space sciences than in previous standards, recommending a year at both the middle and high school levels. The new standards also present a greater emphasis on areas of direct impact between humans and the Earth system, including climate change, natural hazards, resource management, and sustainability.

  17. Space Flight and Manual Control: Implications for Sensorimotor Function on Future Missions

    NASA Technical Reports Server (NTRS)

    Reschke, Millard F.; Kornilova, Ludmila; Tomilovskaya, Elena; Parker, Donald E.; Leigh, R. John; Kozlovskaya, Inessa

    2009-01-01

    Control of vehicles, and other complex mechanical motion systems, is a high-level integrative function of the central nervous system (CNS) that requires good visual acuity, eye-hand coordination, spatial (and, in some cases, geographic) orientation perception, and cognitive function. Existing evidence from space flight research (Paloski et.al., 2008, Clement and Reschke 2008, Reschke et al., 2007) demonstrates that the function of each of these systems is altered by removing (and subsequently by reintroducing) a gravitational field that can be sensed by vestibular, proprioceptive, and haptic receptors and used by the CNS for spatial orientation, navigation, and coordination of movements. Furthermore, much of the operational performance data collected as a function of space flight has not been available for independent analysis, and those data that have been reviewed are equivocal owing to uncontrolled environmental and/or engineering factors. Thus, our current understanding, when it comes to manual control, is limited primarily to a review of those situations where manual control has been a factor. One of the simplest approaches to the manual control problem is to review shuttle landing data. See the Figure below for those landing for which we have Shuttle velocities over the runway threshold.

  18. The Implications of Reduced Ground Reaction Forces During Space Flight for Bone Strains

    NASA Technical Reports Server (NTRS)

    Peterman, Marc M.; Hamel, Andrew J.; Sharkey, Neil A.; Piazza, Stephen J.; Cavanagh, Peter R.

    1998-01-01

    The specific mechanisms regulating bone mass are not known, but most investigators agree that bone maintenance is largely dependent upon mechanical demand and the resultant local bone strains. During space flight, bone loss such as that reported by LeBlanc et al. may result from failure to effectively load the skeleton and generate sufficient localized bone strains. In microgravity, a gravity replacement system can be used to tether an exercising subject to a treadmill. It follows that the ability to prevent bone loss is critically dependent upon the external ground reaction forces (GRFs) and skeletal loads imparted by the tethering system. To our knowledge, the loads during orbital flight have been measured only once (on STS 81). Based on these data and data from ground based experiments, it appears likely that interventions designed to prevent bone loss in micro-gravity generate GRFs substantially less than body weight. It is unknown to what degree reductions in external GRFs will affect internal bone strain and thus the bone maintenance response. To better predict the efficacy of treadmill exercise in micro-gravity we used a unique cadaver model to measure localized bone strains under conditions representative of those that might be produced by a gravity replacement system in space.

  19. Remote sensing from manned low Earth orbit spacecraft: implications for the International Space Station

    NASA Astrophysics Data System (ADS)

    Watson, Patricia Mendoza

    2010-04-01

    This paper addresses the question of what contributions the International Space Station (ISS) can make as a sensor based remote sensing platform. There is precedent for the use of manned platforms in Low Earth Orbit (LEO). Skylab had the Earth Resources Experiment Package (EREP). In the Shuttle -Mir program, the Piroda module was dedicated to Earth sensing. One experiment in the Piroda, the Multispectral Stereo Scanner (MOMS-2PP) was used for quantifying the advantages of performing remote sensing on the ISS. The Space Shuttle program also made significant contributions to Earth observations. Sixteen missions carried electronic experiment packages for Earth observations and crew on almost every mission performed earth observations using cameras. Experiments planned for the ISS can also tell us much about the potential the ISS has as a remote sensing platform by examining their design and objectives. In March of 2009 an experiment called Agricultural Camera (AgCam) was delivered to the ISS for installation in the window of the Laboratory module. In fall of 2009 two more remote sensing experiments will arrive on the ISS - the Hyperspectral Imager for the Coastal Ocean (HICO) and the Remote Atmospheric and Ionospheric Detection System (RAIDS). These instruments will be combined on one experiment package, HICO- RAIDS experiment package (HREP), and will be placed outside the ISS, on an external platform.

  20. Estimating the temporal cutoff-rigidity variations and their implication on manned space missions

    NASA Astrophysics Data System (ADS)

    Herbst, K.; Labrenz, J.; Kopp, A.; Heber, B.; Burmeister, S.; Berger, T.

    2014-12-01

    Using the PLANETOCOSMICS code the vertical cutoff rigidity or equivalently the minimum energy a particle must have in order to reach a given location on Earth is calculated. The program allows investigations that depend on the Earth's magnetic field strength and geometry as a function of time. Today it is well known that the magnetic field is the subject of temporal variations on long as well as short time-scales which reflects itself, e.g., in the global vertical cutoff-rigidity distribution at 20 km altitude (see Herbst et al., 2013). Focusing on the changes during the era of manned space missions (1961-2014) we extend our analysis of the vertical cutoff rigidity variations to about 450 km i.e. to the International Space Station (ISS) orbit. The outcome of this analysis will be compared to measurements of the DOSimetry TELescope (DOSTEL), an instrument that has been operational for several time periods onboard the ISS, allowing to determine the response function of the instrument. Using the Force-Field parameter derived from neutron monitors (see Usoskin et al., 2011) we will present maps of DOSTEL measurements for more than 50 years that are caused by galactic cosmic ray variations along hypothetical ISS orbits.

  1. Improving primary health care facility performance in Ghana: efficiency analysis and fiscal space implications.

    PubMed

    Novignon, Jacob; Nonvignon, Justice

    2017-06-12

    Health centers in Ghana play an important role in health care delivery especially in deprived communities. They usually serve as the first line of service and meet basic health care needs. Unfortunately, these facilities are faced with inadequate resources. While health policy makers seek to increase resources committed to primary healthcare, it is important to understand the nature of inefficiencies that exist in these facilities. Therefore, the objectives of this study are threefold; (i) estimate efficiency among primary health facilities (health centers), (ii) examine the potential fiscal space from improved efficiency and (iii) investigate the efficiency disparities in public and private facilities. Data was from the 2015 Access Bottlenecks, Cost and Equity (ABCE) project conducted by the Institute for Health Metrics and Evaluation. The Stochastic Frontier Analysis (SFA) was used to estimate efficiency of health facilities. Efficiency scores were then used to compute potential savings from improved efficiency. Outpatient visits was used as output while number of personnel, hospital beds, expenditure on other capital items and administration were used as inputs. Disparities in efficiency between public and private facilities was estimated using the Nopo matching decomposition procedure. Average efficiency score across all health centers included in the sample was estimated to be 0.51. Also, average efficiency was estimated to be about 0.65 and 0.50 for private and public facilities, respectively. Significant disparities in efficiency were identified across the various administrative regions. With regards to potential fiscal space, we found that, on average, facilities could save about GH₵11,450.70 (US$7633.80) if efficiency was improved. We also found that fiscal space from efficiency gains varies across rural/urban as well as private/public facilities, if best practices are followed. The matching decomposition showed an efficiency gap of 0.29 between private

  2. Comparison of Reflectance Measurements Acquired with a Contact Probe and an Integration Sphere: Implications for the Spectral Properties of Vegetation at a Leaf Level

    PubMed Central

    Potůčková, Markéta; Červená, Lucie; Kupková, Lucie; Lhotáková, Zuzana; Lukeš, Petr; Hanuš, Jan; Novotný, Jan; Albrechtová, Jana

    2016-01-01

    Laboratory spectroscopy in visible and infrared regions is an important tool for studies dealing with plant ecophysiology and early recognition of plant stress due to changing environmental conditions. Leaf optical properties are typically acquired with a spectroradiometer coupled with an integration sphere (IS) in a laboratory or with a contact probe (CP), which has the advantage of operating flexibility and the provision of repetitive in-situ reflectance measurements. Experiments comparing reflectance spectra measured with different devices and device settings are rarely reported in literature. Thus, in our study we focused on a comparison of spectra collected with two ISs on identical samples ranging from a Spectralon and coloured papers as reference standards to vegetation samples with broadleaved (Nicotiana Rustica L.) and coniferous (Picea abies L. Karst.) leaf types. First, statistical measures such as mean absolute difference, median of differences, standard deviation and paired-sample t-test were applied in order to evaluate differences between collected reflectance values. The possibility of linear transformation between spectra was also tested. Moreover, correlation between normalised differential indexes (NDI) derived for each device and all combinations of wavelengths between 450 nm and 1800 nm were assessed. Finally, relationships between laboratory measured leaf compounds (total chlorophyll, carotenoids and water content), NDI and selected spectral indices often used in remote sensing were studied. The results showed differences between spectra acquired with different devices. While differences were negligible in the case of the Spectralon and they were possible to be modelled with a linear transformation in the case of coloured papers, the spectra collected with the CP and the ISs differed significantly in the case of vegetation samples. Regarding the spectral indices calculated from the reflectance data collected with the three devices, their mean

  3. Comparison of Reflectance Measurements Acquired with a Contact Probe and an Integration Sphere: Implications for the Spectral Properties of Vegetation at a Leaf Level.

    PubMed

    Potůčková, Markéta; Červená, Lucie; Kupková, Lucie; Lhotáková, Zuzana; Lukeš, Petr; Hanuš, Jan; Novotný, Jan; Albrechtová, Jana

    2016-10-28

    Laboratory spectroscopy in visible and infrared regions is an important tool for studies dealing with plant ecophysiology and early recognition of plant stress due to changing environmental conditions. Leaf optical properties are typically acquired with a spectroradiometer coupled with an integration sphere (IS) in a laboratory or with a contact probe (CP), which has the advantage of operating flexibility and the provision of repetitive in-situ reflectance measurements. Experiments comparing reflectance spectra measured with different devices and device settings are rarely reported in literature. Thus, in our study we focused on a comparison of spectra collected with two ISs on identical samples ranging from a Spectralon and coloured papers as reference standards to vegetation samples with broadleaved (Nicotiana Rustica L.) and coniferous (Picea abies L. Karst.) leaf types. First, statistical measures such as mean absolute difference, median of differences, standard deviation and paired-sample t-test were applied in order to evaluate differences between collected reflectance values. The possibility of linear transformation between spectra was also tested. Moreover, correlation between normalised differential indexes (NDI) derived for each device and all combinations of wavelengths between 450 nm and 1800 nm were assessed. Finally, relationships between laboratory measured leaf compounds (total chlorophyll, carotenoids and water content), NDI and selected spectral indices often used in remote sensing were studied. The results showed differences between spectra acquired with different devices. While differences were negligible in the case of the Spectralon and they were possible to be modelled with a linear transformation in the case of coloured papers, the spectra collected with the CP and the ISs differed significantly in the case of vegetation samples. Regarding the spectral indices calculated from the reflectance data collected with the three devices, their mean

  4. American and Japanese control-display stereotypes - Possible implications for design of Space Station systems

    NASA Astrophysics Data System (ADS)

    Wong, Clifford K.; Lyman, John

    The stimulus-response stereotypes of American and Japanese subjects are tested to aid in the determination of guidelines for the design of control-display systems for the Space Station. A set of 24 display configurations were tested to determine the direction which people from the two cultures most frequently turn control knobs to accomplish a certain direction or motion of a pointer in a vertical display. Only one configuration elicited similar and statistically significant reponse stereotypes from both groups. It is shown that the optimal configuration should have the control knob on the right side of the display and the numerical scale on the side of the display opposite to the control knob, with the display pointer pointing away from the knob and the scale markings increasing from bottom to top.

  5. Growth of pea epicotyl in low magnetic field implication for space research

    NASA Astrophysics Data System (ADS)

    Negishi, Y.; Hashimoto, A.; Tsushima, M.; Dobrota, C.; Yamashita, M.; Nakamura, T.

    1999-01-01

    A magnetic field is an inescapable environmental factor for plants on the earth. However, its impact on plant growth is not well understood. In order to survey how magnetic fields affect plant, Alaska pea seedlings were incubated under low magnetic field (LMF) and also in the normal geo-magnetic environment. Two-day-old etiolated seedlings were incubated in a magnetic shield box and in a control box. Sedimentation of amyloplasts was examined in the epicotyls of seedlings grown under these two conditions. The elongation of epicotyls was promoted by LMF. Elongation was most prominent in the middle part of the epicotyls. Cell elongation and increased osmotic pressure of cell sap were found in the epidermal cells exposed to LMF. When the gravitational environment was 1G, the epicotyls incubated under both LMF and normal geomagnetic field grew straight upward and amyloplasts sedimented similarly. However, under simulated microgravity (clinostat), epicotyl and cell elongation was promoted. Furthermore, the epicotyls bent and amyloplasts were dispersed in the cells in simulated microgravity. The dispersion of amyloplasts may relate to the posture control in epicotyl growth under simulated microgravity generated by 3D clinorotation, since it was not observed under LMF in 1G. Since enhanced elongation of cells was commonly seen both at LMF and in simulated microgravity, all elongation on the 3D-clinostat could result from pseudo-low magnetic field, as a by-product of clinorotation. (i.e., clinostat results could be based on randomization of magnetic field together with randomization of gravity vector.) Our results point to the possible use of space for studies in magnetic biology. With space experiments, the effects of dominant environmental factors, such as gravity on plants, could be neutralized or controlled for to reveal magnetic effects more clearly.

  6. Tectonic implications of space-time patterns of Cenozoic magmatism in the western United States

    USGS Publications Warehouse

    Snyder, W.S.; Dickinson, W.R.; Silberman, M.L.

    1976-01-01

    Locations of 2,100 radiometrically dated igneous rocks were plotted on a series of 20 maps, each representing an interval within the period 80 m.y. B.P. to present. Derivative maps showing the distributions in space and time of dated granitic intrusive rocks, silicic lavas and domes, ash-flow tuffs, andesitic-dacitic rocks, and basalts depict well the two main petrogenetic assemblages noted previously by others: (1) mainly intermediate andesitic-dacitic suites, including associated granitic intrusive rocks, silicic extrusive rocks, and minor basaltic lavas, are interpreted as reflecting plate interactions related to subduction along the continental margin; and (2) bimodal suites, dominantly basaltic but with minor silicic extrusive rocks, are interpreted as reflecting extensional tectonics. Space-time distribution of the two assemblages suggests that magmatic arcs extended continously parallel to the continental margin from Canada to Mexico in latest Mesozoic and in Oligocene times. An early Cenozoic null in magmatism in the Great Basin may delineate the region where subduction was arrested temporarily by development of the proto-San Andreas fault as a transform in coastal California or, alternatively, may reflect complex subsurface configurations of subducted plates. The late Cenozoic transition from subduction-related magmatism to extention-related basaltic volcanism in the southern Cordillera occurred at different times in different areas in harmony with current concepts about the migration of the Mendocino triple junction as the modern San Andreas transform fault was formed. The plots also reveal the existence of several discrete magmatic loci where igneous activity of various kinds was characteristically more intense and long-lived than elsewhere. ?? 1976.

  7. Growth of pea epicotyl in low magnetic field: implication for space research.

    PubMed

    Negishi, Y; Hashimoto, A; Tsushima, M; Dobrota, C; Yamashita, M; Nakamura, T

    1999-01-01

    A magnetic field is an inescapable environmental factor for plants on the earth. However, its impact on plant growth is not well understood. In order to survey how magnetic fields affect plant, Alaska pea seedlings were incubated under low magnetic field (LMF) and also in the normal geo-magnetic environment. Two-day-old etiolated seedlings were incubated in a magnetic shield box and in a control box. Sedimentation of amyloplasts was examined in the epicotyls of seedlings grown under these two conditions. The elongation of epicotyls was promoted by LMF. Elongation was most prominent in the middle part of the epicotyls. Cell elongation and increased osmotic pressure of cell sap were found in the epidermal cells exposed to LMF. When the gravitational environment was 1G, the epicotyls incubated under both LMF and normal geomagnetic field grew straight upward and amyloplasts sedimented similarly. However, under simulated microgravity (clinostat), epicotyl and cell elongation was promoted. Furthermore, the epicotyls bent and amyloplasts were dispersed in the cells in simulated microgravity. The dispersion of amyloplasts may relate to the posture control in epicotyl growth under simulated microgravity generated by 3D clinorotation, since it was not observed under LMF in 1G. Since enhanced elongation of cells was commonly seen both at LMF and in simulated microgravity, all elongation on the 3D-clinostat could result from pseudo-low magnetic field, as a by-product of clinorotation. (i.e., clinostat results could be based on randomization of magnetic field together with randomization of gravity vector.) Our results point to the possible use of space for studies in magnetic biology. With space experiments, the effects of dominant environmental factors, such as gravity on plants, could be neutralized or controlled for to reveal magnetic effects more clearly. c1999 COSPAR. Published by Elsevier Science Ltd.

  8. EMISSION-LINE GALAXIES FROM THE HUBBLE SPACE TELESCOPE PROBING EVOLUTION AND REIONIZATION SPECTROSCOPICALLY (PEARS) GRISM SURVEY. I. THE SOUTH FIELDS

    SciTech Connect

    Straughn, Amber N.; Gardner, Jonathan P.; Pirzkal, Norbert; Grogin, Norman; Panagia, Nino; Meurer, Gerhardt R.; Cohen, Seth H.; Windhorst, Rogier A.; Malhotra, Sangeeta; Rhoads, James; Jansen, Rolf A.; Hathi, Nimish P.; Di Serego Alighieri, Sperello; Gronwall, Caryl; Walsh, Jeremy; Pasquali, Anna; Xu, Chun

    2009-10-15

    We present results of a search for emission-line galaxies (ELGs) in the southern fields of the Hubble Space Telescope Probing Evolution And Reionization Spectroscopically (PEARS) grism survey. The PEARS South Fields consist of five Advanced Camera for Surveys pointings (including the Hubble Ultra Deep Field) with the G800L grism for a total of 120 orbits, revealing thousands of faint object spectra in the GOODS-South region of the sky. ELGs are one subset of objects that are prevalent among the grism spectra. Using a two-dimensional detection and extraction procedure, we find 320 emission lines originating from 226 galaxy 'knots' within 192 individual galaxies. Line identification results in 118 new grism-spectroscopic redshifts for galaxies in the GOODS-South Field. We measure emission-line fluxes using standard Gaussian fitting techniques. At the resolution of the grism data, the H{beta} and [O III] doublet are blended. However, by fitting two Gaussian components to the H{beta} and [O III] features, we find that many of the PEARS ELGs have high [O III]/H{beta} ratios compared to other galaxy samples of comparable luminosities. The star formation rates of the ELGs are presented, as well as a sample of distinct giant star-forming regions at z {approx} 0.1-0.5 across individual galaxies. We find that the radial distances of these H II regions in general reside near the galaxies' optical continuum half-light radii, similar to those of giant H II regions in local galaxies.

  9. EMISSION-LINE GALAXIES FROM THE HUBBLE SPACE TELESCOPE PROBING EVOLUTION AND REIONIZATION SPECTROSCOPICALLY (PEARS) GRISM SURVEY. II. THE COMPLETE SAMPLE

    SciTech Connect

    Pirzkal, Nor; Rothberg, Barry; Ly, Chun; Grogin, Norman A.; Dahlen, Tomas; Noeske, Kai G.; Bellini, Andrea; Malhotra, Sangeeta; Rhoads, James E.; Cohen, Seth H.; Mechtley, Matthew; Windhorst, Rogier A.; Meurer, Gerhardt R.; Walsh, Jeremy R.; Hathi, Nimish P.; Holwerda, Benne W.; Straughn, Amber N.

    2013-07-20

    We present a full analysis of the Probing Evolution And Reionization Spectroscopically (PEARS) slitess grism spectroscopic data obtained with the Advanced Camera for Surveys on board Hubble Space Telescope. PEARS covers fields within both the Great Observatories Origins Deep Survey (GOODS) North and South fields, making it ideal as a random survey of galaxies, as well as the availability of a wide variety of ancillary observations complemented by the spectroscopic results. Using the PEARS data, we are able to identify star-forming galaxies (SFGs) within the redshift volume 0 < z < 1.5. Star-forming regions in the PEARS survey are pinpointed independently of the host galaxy. This method allows us to detect the presence of multiple emission-line regions (ELRs) within a single galaxy. We identified a total of 1162 H{alpha}, [O III], and/or [O II] emission lines in the PEARS sample of 906 galaxies to a limiting flux of {approx}10{sup -18} erg s{sup -1} cm{sup -2}. The ELRs have also been compared to the properties of the host galaxy, including morphology, luminosity, and mass. From this analysis, we find three key results: (1) the computed line luminosities show evidence of a flattening in the luminosity function with increasing redshift; (2) the star-forming systems show evidence of complex morphologies with star formation occurring predominantly within one effective (half-light) radius. However, the morphologies show no correlation with host stellar mass. (3) Also, the number density of SFGs with M{sub *} {>=} 10{sup 9} M{sub Sun} decreases by an order of magnitude at z {<=} 0.5 relative to the number at 0.5 < z < 0.9, supporting the argument of galaxy downsizing.

  10. Space Science

    NASA Image and Video Library

    2000-01-01

    In this photo, the Gravity Probe B (GP-B) space vehicle is being assembled at the Sunnyvale, California location of the Lockheed Martin Corporation. The GP-B is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein’s general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth’s rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Underwood, Lockheed Martin Corporation).

  11. Space Science

    NASA Image and Video Library

    2004-01-01

    In this photo, the Gravity Probe B (GP-B) space vehicle is being encapsulated atop the Delta II launch vehicle. The GP-B is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein’s general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth’s rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Underwood, Lockheed Martin Corporation).

  12. Binary black hole mergers: astrophysics and implications for space-based gravitational-wave detectors

    NASA Astrophysics Data System (ADS)

    Lang, Ryan

    2012-03-01

    Massive black holes (MBHs) can be found at the centers of nearly all galaxies. When galaxies merge, the black holes form a binary, which eventually coalesces due to the emission of gravitational waves. The final merger is a complicated process which can only be understood by numerically integrating Einstein's equations of general relativity. For many years, this was an impossible task; however, breakthroughs in 2005 and 2006 led to the first evolutions of binary black hole spacetimes through the merger process. Far from being esoteric results interesting only to hardcore relativists, these simulations have turned out to be very important for astrophysics. For example, if the gravitational waves are emitted asymmetrically, conservation of momentum implies that the resulting black hole will experience a recoil or ``kick.'' Numerical studies have shown that in some configurations, the kick can reach values as large as ˜5000 km/s. The simulations also allow the final spins of the black holes to be calculated. In the future, astrophysical information about coalescing MBH binaries will be obtained by directly measuring the gravitational waves with space-based detectors. In this case, the inclusion of accurate merger and ringdown waveforms into the signal model allows for significant improvement in measuring system parameters like mass, spin, and luminosity distance.

  13. Muscle changes with eccentric exercise: Implications on earth and in space

    NASA Technical Reports Server (NTRS)

    Hargens, Alan R.; Parazynski, Scott; Aratow, Michael; Friden, Jan

    1989-01-01

    Recent investigations of fluid pressure, morpholo gy, and enzyme activities of skeletal muscle exercised eccentrically or concentrically in normal human subjects are reviewed. Intramuscular pressures were measured before, during, and after submaximal exercise and correlated with subjective muscle soreness, fiber size, water content, and blood indices of muscle enzymes. High intensity eccentric exercise is characterized by post exercise pain, elevated intramuscular pressures, and swelling of both type 1 and 2 fibers as compared to concentric exercise. Thus, long periods of unaccustomed, high level eccentric contraction may cause muscle injury, fiber swelling, fluid accumulation, elevated intramuscular pressure, and delayed muscle soreness. Training regimens of progressively increasing eccentric exercise, however, cause less soreness and are extremely efficacious in increasing muscle mass and strength. It is proposed that on Earth, postural muscles are uniquely adapted to low levels of prolonged eccentric contraction that are absent during weightlessness. The almost complete absence of eccentric exercise in space may be an important contributor to muscle atrophy and therefore equipment should be designed to integrate eccentric contractions into exercise protocols for long-term spaceflight.

  14. Restricted N-glycan Conformational Space in the PDB and Its Implication in Glycan Structure Modeling

    PubMed Central

    Jo, Sunhwan; Lee, Hui Sun; Skolnick, Jeffrey; Im, Wonpil

    2013-01-01

    Understanding glycan structure and dynamics is central to understanding protein-carbohydrate recognition and its role in protein-protein interactions. Given the difficulties in obtaining the glycan's crystal structure in glycoconjugates due to its flexibility and heterogeneity, computational modeling could play an important role in providing glycosylated protein structure models. To address if glycan structures available in the PDB can be used as templates or fragments for glycan modeling, we present a survey of the N-glycan structures of 35 different sequences in the PDB. Our statistical analysis shows that the N-glycan structures found on homologous glycoproteins are significantly conserved compared to the random background, suggesting that N-glycan chains can be confidently modeled with template glycan structures whose parent glycoproteins share sequence similarity. On the other hand, N-glycan structures found on non-homologous glycoproteins do not show significant global structural similarity. Nonetheless, the internal substructures of these N-glycans, particularly, the substructures that are closer to the protein, show significantly similar structures, suggesting that such substructures can be used as fragments in glycan modeling. Increased interactions with protein might be responsible for the restricted conformational space of N-glycan chains. Our results suggest that structure prediction/modeling of N-glycans of glycoconjugates using structure database could be effective and different modeling approaches would be needed depending on the availability of template structures. PMID:23516343

  15. Operational implications of a cloud model simulation of space shuttle exhaust clouds in different atmospheric conditions

    NASA Technical Reports Server (NTRS)

    Zak, J. A.

    1989-01-01

    A three-dimensional cloud model was used to characterize the dominant influence of the environment on the Space Shuttle exhaust cloud. The model was modified to accept the actual heat and moisture from rocket exhausts and deluge water as initial conditions. An upper-air sounding determined the ambient atmosphere in which the cloud would grow. The model was validated by comparing simulated clouds with observed clouds from four actual Shuttle launches. Results are discussed with operational weather forecasters in mind. The model successfully produced clouds with dimensions, rise, decay, liquid water contents, and vertical motion fields very similar to observed clouds whose dimensions were calculated from 16 mm film frames. Once validated, the model was used in a number of different atmospheric conditions ranging from very unstable to very stable. Wind shear strongly affected the appearance of both the ground cloud and vertical column cloud. The ambient low-level atmospheric moisture governed the amount of cloud water in model clouds. Some dry atmospheres produced little or no cloud water. An empirical forecast technique for Shuttle cloud rise is presented and differences between natural atmospheric convection and exhaust clouds are discussed.

  16. Distributions in Protein Conformation Space: Implications for Structure Prediction and Entropy

    PubMed Central

    Sullivan, David C.; Kuntz, Irwin D.

    2004-01-01

    By considering how polymer structures are distributed in conformation space, we show that it is possible to quantify the difficulty of structural prediction and to provide a measure of progress for prediction calculations. The critical issue is the probability that a conformation is found within a specified distance of another conformer. We address this question by constructing a cumulative distribution function (CDF) for the average probability from observations about its limiting behavior at small displacements and numerical simulations of polyalanine chains. We can use the CDF to estimate the likelihood that a structure prediction is better than random chance. For example, the chance of randomly predicting the native backbone structure of a 150-amino-acid protein to low resolution, say within 6 Å, is 10−14. A high-resolution structural prediction, say to 2 Å, is immensely more difficult (10−57). With additional assumptions, the CDF yields the conformational entropy of protein folding from native-state coordinate variance. Or, using values of the conformational entropy change on folding, we can estimate the native state's conformational span. For example, for a 150-mer protein, equilibrium α-carbon displacements in the native ensemble would be 0.3–0.5 Å based on TΔS of 1.42 kcal/(mol residue). PMID:15240450

  17. Bone Loss During Space Flights: Implication of the Vestibular System, Sex-Dependence and Countermeasure

    NASA Astrophysics Data System (ADS)

    Vignaux, G.; Besnard, S.; Philoxene, B.; Sabatier, J. P.; Allouche, S.; Denise, P.

    2008-06-01

    The decrease of mechanical load due to microgravity induces bone loss (BL) during long-term space flights. We previously postulated that vestibular system could also be involved in bone modeling. Herein, we evaluated by tomography, long-term (2 months) effects of bilateral vestibular lesion (Bilab) on BL compared to a model of diffuse osteoporosis induced by gonadectomy in male and female rats. BL (about 12%) was observed on femoral metaphysis and femoral metaphysis/diaphysis respectively in male and female Bilab groups compared to shams. Whole body and spine mineralization remained unchanged in Bilab groups while it appeared decreased in gonadectomy groups as expected. BL in Bilab groups was reported at 1 month and recovered at 2 months while it remained decreased at 2 months in our model of diffuse osteoporosis. Risedronate over counterbalanced BL in both models of BL (Bilab and gonadectomy) at 1 and 2 months. Bilateral vestibular lesions on Earth induced regional bone loss focused on bearing bones in male and female at 1 month with unknown compensatory mechanisms 2 months later.

  18. Instability of ocular torsion in zero gravity - Possible implications for space motion sickness

    NASA Technical Reports Server (NTRS)

    Diamond, Shirley G.; Markham, Charles H.; Money, Ken E.

    1990-01-01

    It is proposed that study of the eye torsion reflex and its behavior under novel gravitational states may possibly provide the basis for a long-sought test to predict space motion sickness (SMS). Measures of eye torsion such as ocular counterrolling and spontaneous eye torsion, were examined during hypo- and hypergravity in parabolic flight on the NASA KC-135 aircraft. Ten subjects, including two astronauts, one who had experienced SMS and one who had not, were ranked according to scores of torsional inability at 0 G and divided into two equal groups of high and low susceptibility to SMS. At 1.8 G the groups were significantly different in both the instability measure and the measure of torsional ability. No differences were detected in eye torsion in either 0 G or 1.8 G and none of the tests were significantly different in 1 G. Results suggest that tests of eye torsion on the KC-135 might differentiate those who would experience SMS from those who would not, although it is noted that this is not yet proven.

  19. Instability of ocular torsion in zero gravity - Possible implications for space motion sickness

    NASA Technical Reports Server (NTRS)

    Diamond, Shirley G.; Markham, Charles H.; Money, Ken E.

    1990-01-01

    It is proposed that study of the eye torsion reflex and its behavior under novel gravitational states may possibly provide the basis for a long-sought test to predict space motion sickness (SMS). Measures of eye torsion such as ocular counterrolling and spontaneous eye torsion, were examined during hypo- and hypergravity in parabolic flight on the NASA KC-135 aircraft. Ten subjects, including two astronauts, one who had experienced SMS and one who had not, were ranked according to scores of torsional inability at 0 G and divided into two equal groups of high and low susceptibility to SMS. At 1.8 G the groups were significantly different in both the instability measure and the measure of torsional ability. No differences were detected in eye torsion in either 0 G or 1.8 G and none of the tests were significantly different in 1 G. Results suggest that tests of eye torsion on the KC-135 might differentiate those who would experience SMS from those who would not, although it is noted that this is not yet proven.

  20. Cholera cases cluster in time and space in Matlab, Bangladesh: implications for targeted preventive interventions.

    PubMed

    Debes, Amanda K; Ali, Mohammad; Azman, Andrew S; Yunus, Mohammad; Sack, David A

    2016-12-01

    : Cholera remains a serious public health threat in Asia, Africa and in parts of the Americas. Three World health Organization (WHO) pre-qualified oral cholera vaccines are now available but their supply is limited, so current supplies must be administered strategically. This requires an improved understanding of disease transmission and control strategies. : We used demographics and disease surveillance data collected from 1991 to 2000 in Matlab, Bangladesh, to estimate the spatial and temporal extent of the zone of increased risk around cholera cases. Specifically, we compare the cholera incidence among individuals living close to cholera cases with that among individuals living close to those without medically-attended cholera in this rural endemic setting. : Those living within 50 m of a confirmed cholera case had 36 times (95% confidence interval: 23-56) the risk of becoming a cholera case in the first 3 days (after case presentation) compared with risk elsewhere in the community. The relative risk gradually declined in space and time, but remained significantly high up to 450 me away within 3 days of case presentation, and up to 150 m away within 23 days from the date of presentation of the case. : These findings suggest that, if conducted rapidly, vaccinating individuals living close to a case (ring vaccination) could be an efficient and effective strategy to target vaccine to a high-risk population in an endemic setting.

  1. Stability constraints for oceanic numerical models: implications for the formulation of space-time discretizations

    NASA Astrophysics Data System (ADS)

    Lemarie, Florian; Debreu, Laurent; Madec, Gurvan

    2015-04-01

    Except for vertical diffusion (and possibly the external mode and bottom drag), oceanic models usually rely on explicit time-stepping algorithms subject to Courant-Friedrichs-Lewy (CFL) stability criteria. Implicit methods could be unconditionally stable, but an algebraic system must be solved at each time step and other considerations such as accuracy and efficiency are less straightforward to achieve. Depending on the target application, the process limiting the maximum allowed time-step is generally different. In this study, we introduce offline diagnostics to predict stability limits associated with internal gravity waves, advection, diffusion, and rotation. This suite of diagnostics is applied to a set of global, regional and coastal numerical simulations with several horizontal/vertical resolutions and different numerical models. We show that, for resolutions finer that 1/2°, models with an eulerian vertical coordinate are generally constrained by vertical advection in a few hot spots and that numerics must be extremely robust to changes in Courant number. Based on those results, we review the stability and accuracy of existing numerical kernels in vogue in primitive equations oceanic models with a focus on advective processes and the dynamics of internal waves. We emphasize the additional value of studying the numerical kernel of oceanic models in the light of coupled space-time approaches instead of studying the time schemes independently from spatial discretizations. From this study, we suggest some guidelines for the development of temporal schemes in future generation multi-purpose oceanic models.

  2. Stability constraints for oceanic numerical models: implications for the formulation of time and space discretizations

    NASA Astrophysics Data System (ADS)

    Lemarié, F.; Debreu, L.; Madec, G.; Demange, J.; Molines, J. M.; Honnorat, M.

    2015-08-01

    Except for vertical diffusion (and possibly the external mode and bottom drag), oceanic models usually rely on explicit time-stepping algorithms subject to Courant-Friedrichs-Lewy (CFL) stability criteria. Implicit methods could be unconditionally stable, but an algebraic system must be solved at each time step and other considerations such as accuracy and efficiency are less straightforward to achieve. Depending on the target application, the process limiting the maximum allowed time-step is generally different. In this paper, we introduce offline diagnostics to predict stability limits associated with internal gravity waves, advection, diffusion, and rotation. This suite of diagnostics is applied to a set of global, regional and coastal numerical simulations with several horizontal/vertical resolutions and different numerical models. We show that, for resolutions finer that 1/2°, models with an Eulerian vertical coordinate are generally constrained by vertical advection in a few hot spots and that numerics must be extremely robust to changes in Courant number. Based on those results, we review the stability and accuracy of existing numerical kernels in vogue in primitive equations oceanic models with a focus on advective processes and the dynamics of internal waves. We emphasize the additional value of studying the numerical kernel of oceanic models in the light of coupled space-time approaches instead of studying the time schemes independently from spatial discretizations. From this study, we suggest some guidelines for the development of temporal schemes in future generation multi-purpose oceanic models.

  3. Gas embolism and surfactant-based intervention: implications for long-duration space-based activity.

    PubMed

    Eckmann, David M; Zhang, Jie; Lampe, Joshua; Ayyaswamy, Portonovo S

    2006-09-01

    Intravascular gas embolism can occur with decompression in space flight, and it commonly occurs during cardiac and vascular surgery. Intravascular bubbles may be deposited into any end organ such as the heart or the brain. Surface interactions between the bubble and the endothelial cells lining the vasculature result in serious impairment of blood flow and can lead to heart attack, stroke, or even death. Surfactant-based intervention is a novel treatment for gas embolism. Intravascular surfactant can adsorb onto the gas-liquid interface and compete with blood-borne macromolecules for interfacial occupancy. Surfactants can retard the progress of pathophysiological molecular and cellular events stimulated by the bubble surface, including endothelial cell injury and initiation of blood clotting. Bulk and surface transport of a surfactant to provide competition for interfacial occupancy is a therapeutic strategy because surfactant adsorption can dominate protein (or other macromolecule) adsorption. The presence of surfactant along the gas-liquid interface also induces variation in the interfacial tension, which in turn affects the blood flow and the bubble motion. We describe the interplay between biological transport processes and physiological events occurring and the cellular and molecular level in vascular gas embolization. Special consideration is given to modeling the transport and hydrodynamic interactions associated with surfactant-based intervention.

  4. Acute Meteorite Dust Exposure and Pulmonary Inflammation - Implications for Human Space Exploration

    NASA Technical Reports Server (NTRS)

    Harrington, A. D.; McCubbin, F. M.; Kaur, J.; Smirnov, A.; Galdanes, K.; Schoonen, M. A. A.; Chen, L. C.; Tsirka, S. E.; Gordon, T.

    2017-01-01

    The previous manned missions to the Moon represent milestones of human ingenuity, perseverance, and intellectual curiosity. However, one of the major ongoing concerns is the array of hazards associated with lunar surface dust. Not only did the dust cause mechanical and structural integrity issues with the suits, the dust 'storm' generated upon reentrance into the crew cabin caused "lunar hay fever" and "almost blindness [1-3]" (Figure 1). It was further reported that the allergic response to the dust worsened with each exposure [4]. The lack of gravity exacerbated the exposure, requiring the astronauts to wear their helmet within the module in order to avoid breathing the irritating particles [1]. Due to the prevalence of these high exposures, the Human Research Roadmap developed by NASA identifies the Risk of Adverse Health and Performance Effects of Celestial Dust Exposure as an area of concern [5]. Extended human exploration will further increase the probability of inadvertent and repeated exposures to celestial dusts. Going forward, hazard assessments of celestial dusts will be determined through sample return efforts prior to astronaut deployment. Studies on the lunar highland regolith indicate that the dust is not only respirable but also reactive [2, 6-9], and previous studies concluded that it is moderately toxic; generating a greater response than titanium oxide but a lower response than quartz [6]. The presence of reactive oxygen species (ROS) on the surface of the dust has been implicated. However, there is actually little data related to physicochemical characteristics of particulates and pulmonary toxicity, especially as it relates to celestial dust exposure. As a direct response to this deficit, the present study evaluates the role of a particulate's innate geochemical features (e.g., bulk chemistry, internal composition, morphology, size, and reactivity) in generating adverse toxicological responses in vitro and in vivo. This highly interdisciplinary

  5. Pulmonary Inflammatory Responses To Acute Meteorite Dust Exposures - Implications For Human Space Exploration

    NASA Technical Reports Server (NTRS)

    Harrington, A. D.; McCubbin, F. M.; Kaur, J.; Smirnov, A.; Galdanes, K.; Schoonen, M. A. A.; Chen, L. C.; Tsirka, S. E.; Gordon, T.

    2017-01-01

    The previous manned missions to the Moon represent milestones of human ingenuity, perseverance, and intellectual curiosity. However, one of the major ongoing concerns is the array of hazards associated with lunar surface dust. Not only did the dust cause mechanical and structural integrity issues with the suits, the dust 'storm' generated upon reentrance into the crew cabin caused "lunar hay fever" and "almost blindness" (Figure 1). It was further reported that the allergic response to the dust worsened with each exposure. The lack of gravity exacerbated the exposure, requiring the astronauts to wear their helmet within the module in order to avoid breathing the irritating particles. Due to the prevalence of these high exposures, the Human Research Roadmap developed by NASA identifies the Risk of Adverse Health and Performance Effects of Celestial Dust Exposure as an area of concern. Extended human exploration will further increase the probability of inadvertent and repeated exposures to celestial dusts. Going forward, hazard assessments of celestial dusts will be determined through sample return efforts prior to astronaut deployment. Studies on the lunar highland regolith indicate that the dust is not only respirable but also reactive, and previous studies concluded that it is moderately toxic; generating a greater response than titanium oxide but a lower response than quartz. The presence of reactive oxygen species (ROS) on the surface of the dust has been implicated. However, there is actually little data related to physicochemical characteristics of particulates and pulmonary toxicity, especially as it relates to celestial dust exposure. As a direct response to this deficit, the present study evaluates the role of a particulate's innate geochemical features (e.g., bulk chemistry, internal composition, morphology, size, and reactivity) in generating adverse toxicological responses in vitro and in vivo. This highly interdisciplinary study evaluates the relative

  6. Geological assessment probe

    NASA Astrophysics Data System (ADS)

    Collins, E. R.

    1980-04-01

    A probe is described which can be installed in a side hole that extends from a bore hole in the Earth, to assess the permeability of the strata surrounding the borehole. The probe is elongated and has a plurality of seals spaced therealong and sealed to the walls of the side hole to form a plurality of chambers sealed from one another. A tracer fluid injector on the probe can inject a tracer fluid into one of the chambers, while a tracer fluid detector located in another chamber can detect the tracer fluid, to thereby sense the permeability of the strata surrounding the side hole. The probe can include a train of modules, with each module having an inflatable packer which is inflated by the difference between the borehole pressure and the strata pressure.

  7. Atmospheric entry probes for outer planet exploration. Outer planet entry probe technical summary

    NASA Technical Reports Server (NTRS)

    1974-01-01

    The use of unmanned space probes for investigating the conditions existing on and around the outer planets of the solar system is discussed. The subjects included in the report are: (1) the design of a common entry probe for outer planet missions, (2) the significant trades related to the development of a common probe design, (3) the impact of bus selection on probe design, (4) the impact of probe requirements on bus modifications, and (5) the key technology elements recommended for advanced development. Drawings and illustrations of typical probes are included to show the components and systems used in the space probes.

  8. Cratering and penetration experiments in aluminum and teflon: Implications for space-exposed surfaces

    NASA Astrophysics Data System (ADS)

    Hörz, Friedrich

    2012-04-01

    Whether a target is penetrated or not during hypervelocity impact depends strongly on typical impactor dimensions (Dp) relative to the absolute target thickness (T). We have therefore conducted impact experiments in aluminum1100 and TeflonFEP targets that systematically varied Dp/T (=D*), ranging from genuine cratering events in thick targets (Dp << T) to the nondisruptive passage of the impactor through very thin films (Dp >> T). The objectives were to (1) delineate the transition from cratering to penetration events, (2) characterize the diameter of the penetration hole (Dh) as a function of D*, and (3) determine the threshold target thickness that yields Dh = Dp. We employed spherical soda-lime glass (SLG) projectiles of Dp = 50-3175 μm at impact velocities (V) from 1 to 7 km s-1, and varied target thicknesses from microns to centimeters. The transition from cratering to penetration processes in thick targets forms a continuum in all morphologic aspects. The entrance side of the target resembles that of a standard crater even when the back of the target suffers substantial, physical perforations via spallation and plastic deformation. We thus suggest that the cratering-to-penetration transition does not occur when the target becomes physically perforated (i.e., at the "ballistic limit"), but when the shock pulse duration in the projectile (tp) is identical to that in the target (tt), i.e., tp = tt. This condition is readily calculated from equation-of-state data. As a consequence, in reconstructing impactor dimensions from observations of space-exposed substrates, we recommend that crater size (Dc) be used for the case of tp < tt, and that penetration hole diameter (Dh) be used when tp > tt. The morphologic evolution of the penetration hole and its size also forms a continuum that strongly depends on both the scaled parameter D* and on V, but it is independent of the absolute scale. The condition of Dh = Dp is approached at D* > 50. The dependence of Dh on T

  9. Atmospheric methane observed from space over the Asian monsoon: implications for emission from Asian rice paddies

    NASA Astrophysics Data System (ADS)

    Hayashida, S.; Yoshizaki, S.; Frankenberg, C.; Yan, X.

    2010-12-01

    More than 40% of anthropogenic emissions of methane, the second most important greenhouse gas, is estimated to be from agricultural sources, including rice cultivation. Unfortunately, the strength of individual sources of methane remains uncertain, despite the importance of its effect in global warming. Here we focus on the Asian monsoon region to improve our understanding of methane emission from rice paddy fields. This region contains about 90% of the world’s rice fields. We analyze the temporal and spatial distribution of atmospheric methane concentrations observed from space and compare it with ground-based measurements and bottom-up emission inventory data coupled with rice field maps. Recently, Frankenberg et al. [2008] derived an updated version of methane concentration from the Scanning Imaging Absorption Spectrometer for Atmospheric Chartography (SCIAMACHY: SCIA hereafter) instrument onboard ENVISAT. This showed a clear signature of methane enhancement over the Asian monsoon. As SCIA retrievals include all involve column densities, we carefully examined potential biases and variability due to the gradient of methane concentration over source regions by comparing these data with ground-based measurements at 53 stations of the WDCGG network. After evaluating the bias and variability of methane concentration over the source regions, we examined selected areas where rice paddies were highly concentrated, and the methane emission inventories were estimated to be large. The sampled areas were North and South India, Bangladesh, Myanmar, Thailand, South China, and the Sichuan Basin. All of these are known to be major rice cultivation areas. The time series of monthly mean SCIA retrievals were compared with the emission inventory data for rice cultivation archived in the GISS dataset and Yan et al. [2009], as well as with precipitation data (Huffman et al., 1997). The phase of seasonal variation of SCIA retrievals corresponded closely to those of emission

  10. Space Science

    NASA Image and Video Library

    2001-08-01

    The Gravity Probe B (GP-B) payload was hoisted by crane to the transportation truck in the W.W. Hansen Experimental Physics Laboratory in Stanford, California for shipment to the launch site at Vandenburg Air Force Base. GP-B is the relativity experiment being developed at Stanford University to test two extraordinary predictions of Albert Einstein’s general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth’s rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004, the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University, along with major subcontractor Lockheed Martin Corporation. (Photo Credit: Stanford University)

  11. Space Science

    NASA Image and Video Library

    2004-01-01

    In this photo, the Gravity Probe B (GP-B) detector mount assembly is shown in comparison to the size of a dime. The assembly is used to detect exactly how much starlight is coming through different beams from the beam splitter in the telescope. The measurements from the tiny chips inside are what keeps GP-B aimed at the guide star. The GP-B is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein’s general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth’s rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Paul Ehrensberger, Stanford University.)

  12. The Ethical Implications of Cultural Intervention by Space-faring Civilizations -- What Science Fiction Has to Say

    NASA Astrophysics Data System (ADS)

    Ciupa, M.

    Science fiction (Scifi) plays out the concerns of our possible scientistic futures; it is a source for exploring the deep rooted psychological concerns of mankind with science and the humanities. In this paper it is proposed Scifi is a valid source of hypotheses to examine, not as "evidence", but as candidate ­ often cautionary ­ notions, i.e., scenarios to be studied. Scifi represents a kind of Jungian mythological based story-telling, putting forward tales that express our conscious/unconscious concerns. Thus, when looking into ethical questions like, "where will techno-progressive futures take us?", we import into them these archetypes, hopes and fears, as a result they frequently reappear as familiar tropes. In this respect it is appropriate not to ignore them, but to openly challenge/appreciate them: to see what scenarios are indeed likely and how they may impact us reciprocally. This paper examines some of these aspects, and provides examples of how they are represented in the Scifi genre, in particular with consideration of the ethical implications of cultural intervention by space-faring civilizations. Given the specific analysis/examples provided, it concludes with an ethical scenario analysis (a dialectic argument), within the limiting conditions of the Drake Equation, Fermi Paradox and Cultural History. It comments on the potential existential risk of the Active SETI programmes recently initiated, indeed the need for an ethical exosociological review of all proposed Interstellar projects that express an "Intervention-Propensity".

  13. Considering the Ethical Implications of Space Exploration and Potential Impacts on Planetary Environments and Possible Indigenous Life

    NASA Astrophysics Data System (ADS)

    Race, Margaret

    Since the early days of the Outer Space Treaty, a primary concern of planetary protection policy has been to avoid contamination of planetary environments by terrestrial microbes that could compromise current or subsequent scientific investigations, particularly those searching for indigenous life. Over the past decade robotic missions and astrobiological research have greatly increased our understanding of diverse planetary landscapes and altered our views about the survivability of terrestrial organisms in extreme environments. They have also expanded notions about the prospect for finding evidence of extraterrestrial life. Recently a number of different groups, including the COSPAR Planetary Protection Workshop in Montreal (January 2008), have questioned whether it is advisable to re-examine current biological planetary protection policy in light of the ethical implications and responsibilities to preserve planetary environments and possible indigenous life. This paper discusses the issues and concerns that have led to recent recommendations for convening an international workshop specifically to discuss planetary protection policy and practices within a broader ethical and practical framework, and to consider whether revisions to policy and practices should be made. In addition to including various international scientific and legal organizations and experts in such a workshop, it will be important to find ways to involve the public in these discussions about ethical aspects of planetary exploration.

  14. Probing dimensionality using a simplified 4-probe method

    NASA Astrophysics Data System (ADS)

    Kjeldby, Snorre B.; Evenstad, Otto M.; Cooil, Simon P.; Wells, Justin W.

    2017-10-01

    4-probe electrical measurements have been in existence for many decades. One of the most useful aspects of the 4-probe method is that it is not only possible to find the resistivity of a sample (independently of the contact resistances), but that it is also possible to probe the dimensionality of the sample. In theory, this is straightforward to achieve by measuring the 4-probe resistance as a function of probe separation. In practice, it is challenging to move all four probes with sufficient precision over the necessary range. Here, we present an alternative approach. We demonstrate that the dimensionality of the conductive path within a sample can be directly probed using a modified 4-probe method in which an unconventional geometry is exploited; three of the probes are rigidly fixed, and the position of only one probe is changed. This allows 2D and 3D (and other) contributions the to resistivity to be readily disentangled. The required experimental instrumentation can be vastly simplified relative to traditional variable spacing 4-probe instruments.

  15. Uptake and localization mechanisms of fluorescent and colored lipid probes. Part 2. QSAR models that predict localization of fluorescent probes used to identify ("specifically stain") various biomembranes and membranous organelles.

    PubMed

    Horobin, R W; Stockert, J C; Rashid-Doubell, F

    2015-05-01

    We discuss a variety of biological targets including generic biomembranes and the membranes of the endoplasmic reticulum, endosomes/lysosomes, Golgi body, mitochondria (outer and inner membranes) and the plasma membrane of usual fluidity. For each target, we discuss the access of probes to the target membrane, probe uptake into the membrane and the mechanism of selectivity of the probe uptake. A statement of the QSAR decision rule that describes the required physicochemical features of probes that enable selective staining also is provided, followed by comments on exceptions and limits. Examples of probes typically used to demonstrate each target structure are noted and decision rule tabulations are provided for probes that localize in particular targets; these tabulations show distribution of probes in the conceptual space defined by the relevant structure parameters ("parameter space"). Some general implications and limitations of the QSAR models for probe targeting are discussed including the roles of certain cell and protocol factors that play significant roles in lipid staining. A case example illustrates the predictive ability of QSAR models. Key limiting values of the head group hydrophilicity parameter associated with membrane-probe interactions are discussed in an appendix.

  16. Comparison between gradient-dependent hydraulic conductivities of roots using the root pressure probe: the role of pressure propagations and implications for the relative roles of parallel radial pathways.

    PubMed

    Bramley, Helen; Turner, Neil C; Turner, David W; Tyerman, Stephen D

    2007-07-01

    Hydrostatic pressure relaxations with the root pressure probe are commonly used for measuring the hydraulic conductivity (Lp(r)) of roots. We compared the Lp(r) of roots from species with different root hydraulic properties (Lupinus angustifolius L. 'Merrit', Lupinus luteus L. 'Wodjil', Triticum aestivum L. 'Kulin' and Zea mays L. 'Pacific DK 477') using pressure relaxations, a pressure clamp and osmotic gradients to induce water flow across the root. Only the pressure clamp measures water flow under steady-state conditions. Lp(r) determined by pressure relaxations was two- to threefold greater than Lp(r) from pressure clamps and was independent of the direction of water flow. Lp(r) (pressure clamp) was two- to fourfold higher than for Lp(r) (osmotic) for all species except Triticum aestivum where Lp(r) (pressure clamp) and Lp(r) (osmotic) were not significantly different. A novel technique was developed to measure the propagation of pressure through roots to investigate the cause of the differences in Lp(r). Root segments were connected between two pressure probes so that when root pressure (P(r)) was manipulated by one probe, the other probe recorded changes in P(r). Pressure relaxations did not induce the expected kinetics in pressure in the probe at the other end of the root when axial hydraulic conductance, and probe and root capacitances were accounted for. An electric circuit model of the root was constructed that included an additional capacitance in the root loaded by a series of resistances. This accounted for the double exponential kinetics for intact roots in pressure relaxation experiments as well as the reduced response observed with the double probe experiments. Although there were potential errors with all the techniques, we considered that the measurement of Lp(r) using the pressure clamp was the most unambiguous for small pressure changes, and provided that sufficient time was allowed for pressure propagation through the root. The differences in

  17. Gravity Probe B

    NASA Image and Video Library

    2003-07-12

    The Gravity Probe B experiment is lifted from its transporter in the spacecraft processing facility on North Vandenberg Air Force Base. Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  18. Gravity Probe B

    NASA Image and Video Library

    2003-07-12

    The Gravity Probe B experiment is lowered onto an assembly and test stand in the spacecraft processing facility on North Vandenberg Air Force Base. Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  19. Gravity Probe B

    NASA Image and Video Library

    2003-07-13

    In the spacecraft processing facility on North Vandenberg Air Force Base, workers prepare to remove the soft shipping cover from the Gravity Probe B experiment. Immediate processing includes setting up mechanical and electrical ground support equipment, making necessary connections and conditioning the spacecraft battery. The Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  20. Gravity Probe B

    NASA Image and Video Library

    2003-07-18

    In the spacecraft processing facility on North Vandenberg Air Force Base, workers conduct battery charge/discharge cycles as part of the battery conditioning process on Gravity Probe B. The Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  1. Gravity Probe B

    NASA Image and Video Library

    2003-07-12

    The Gravity Probe B experiment enters the spacecraft processing facility on North Vandenberg Air Force Base. Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  2. Gravity Probe B

    NASA Image and Video Library

    2003-07-12

    A transporter carrying the Gravity Probe B experiment backs into the spacecraft processing facility on North Vandenberg Air Force Base. Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  3. Gravity Probe B

    NASA Image and Video Library

    2003-07-12

    Enclosed in a canister, the Gravity Probe B (GP-B) spacecraft arrives on Vandenberg Air Force Base, headed for the spacecraft processing facility. Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  4. Gravity Probe B

    NASA Image and Video Library

    2003-07-11

    Workers in the spacecraft processing facility on North Vandenberg Air Force Base get ready to begin processing the Gravity Probe B experiment, including setting up mechanical and electrical ground support equipment, making necessary connections and conditioning the spacecraft battery. The Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  5. Gravity Probe B

    NASA Image and Video Library

    2003-07-12

    The Gravity Probe B experiment rests on an assembly and test stand in the spacecraft processing facility on North Vandenberg Air Force Base. Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  6. Gravity Probe B

    NASA Image and Video Library

    2003-07-12

    At Vandenberg AFB, the canister enclosing the Gravity Probe B (GP-B) spacecraft is removed from the transporter. Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  7. Gravity Probe B

    NASA Image and Video Library

    2003-07-11

    Workers in the spacecraft processing facility on North Vandenberg Air Force Base get ready to begin processing the Gravity Probe B experiment. Mechanical and electrical ground support equipment will be set up and necessary connections made with the spacecraft. Spacecraft battery conditioning will also begin. The Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  8. Gravity Probe B

    NASA Image and Video Library

    2003-07-18

    In the spacecraft processing facility on North Vandenberg Air Force Base, battery charge/discharge cycles are underway as part of the battery conditioning process on Gravity Probe B. The Gravity Probe B will launch a payload of four gyroscopes into low-Earth polar orbit to test two extraordinary predictions of Albert Einstein’s general theory of relativity: the geodetic effect (how space and time are warped by the presence of the Earth) and frame dragging (how Earth’s rotation drags space and time around with it). Once in orbit, for 18 months each gyroscope’s spin axis will be monitored as it travels through local spacetime, observing and measuring these effects. The experiment was developed by Stanford University, Lockheed Martin and NASA’s Marshall Space Flight Center.

  9. Floating Potential Probe Langmuir Probe Data Reduction Results

    NASA Technical Reports Server (NTRS)

    Morton, Thomas L.; Minow, Joseph I.

    2002-01-01

    During its first five months of operations, the Langmuir Probe on the Floating Potential Probe (FPP) obtained data on ionospheric electron densities and temperatures in the ISS orbit. In this paper, the algorithms for data reduction are presented, and comparisons are made of FPP data with ground-based ionosonde and Incoherent Scattering Radar (ISR) results. Implications for ISS operations are detailed, and the need for a permanent FPP on ISS is examined.

  10. Clinical Correlates, Ethnic Differences, and Prognostic Implications of Perivascular Spaces in Transient Ischemic Attack and Ischemic Stroke.

    PubMed

    Lau, Kui-Kai; Li, Linxin; Lovelock, Caroline E; Zamboni, Giovanna; Chan, Tsz-Tai; Chiang, Man-Fung; Lo, Kin-Ting; Küker, Wilhelm; Mak, Henry Ka-Fung; Rothwell, Peter M

    2017-06-01

    Perivascular spaces (PVSs) are considered markers of small vessel disease. However, their long-term prognostic implications in transient ischemic attack/ischemic stroke patients are unknown. Ethnic differences in PVS prevalence are also unknown. Two independent prospective studies were conducted, 1 comprising predominantly whites with transient ischemic attack/ischemic stroke (OXVASC [Oxford Vascular] study) and 1 comprising predominantly Chinese with ischemic stroke (University of Hong Kong). Clinical and imaging correlates, prognostic implications for stroke and death, and ethnic differences in basal ganglia (BG) and centrum semiovale (CS) PVSs were studied with adjustment for age, sex, vascular risk factors, and scanner strength. Whites with transient ischemic attack/ischemic stroke (n=1028) had a higher prevalence of both BG and CS-PVSs compared with Chinese (n=974; >20 BG-PVSs: 22.4% versus 7.1%; >20 CS-PVSs: 45.8% versus 10.4%; P<0.0001). More than 20 BG or CS-PVSs were both associated with increasing age and white matter hyperintensity, although associations with BG-PVSs were stronger (all P<0.0001). During 6924 patient-years of follow-up, BG-PVSs were also independently associated with an increased risk of recurrent ischemic stroke (adjusted hazard ratio compared with <11 PVSs, 11-20 PVSs: HR, 1.15; 95% confidence interval, 0.78-1.68; >20 PVSs: HR, 1.82; 1.18-2.80; P=0.011) but not intracerebral hemorrhage (P=0.10) or all-cause mortality (P=0.16). CS-PVSs were not associated with recurrent stroke (P=0.57) or mortality (P=0.072). Prognostic associations were similar in both cohorts. Over and above ethnic differences in frequency of PVSs in transient ischemic attack/ischemic stroke patients, BG and CS-PVSs had similar risk factors, but although >20 BG-PVSs were associated with an increased risk of recurrent ischemic stroke, CS-PVSs were not. © 2017 The Authors.

  11. Gravity Probe B Completed With Solar Arrays

    NASA Technical Reports Server (NTRS)

    2004-01-01

    In this photo, the Gravity Probe B (GP-B) space vehicle is completed during the solar array installation. The GP-B is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. GP-B is scheduled for launch in April 2004 and managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Underwood, Lockheed Martin Corporation).

  12. Gravity Probe B Completed With Solar Arrays

    NASA Technical Reports Server (NTRS)

    2004-01-01

    In this photo, the Gravity Probe B (GP-B) space vehicle is completed during the solar array installation. The GP-B is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. GP-B is scheduled for launch in April 2004 and managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Underwood, Lockheed Martin Corporation).

  13. Results of the space shuttle vehicle ascent air data system probe calibration test using a 0.07-scale external tank forebody model (68T) in the AEDC 16-foot transonic wind tunnel (IA-310), volume 1

    NASA Technical Reports Server (NTRS)

    Collette, J. G. R.

    1991-01-01

    A recalibration of the Space Shuttle Vehicle Ascent Air Data System probe was conducted in the Arnold Engineering Development Center (AEDC) transonic wind tunnel. The purpose was to improve on the accuracy of the previous calibration in order to reduce the existing uncertainties in the system. A probe tip attached to a 0.07-scale External Tank Forebody model was tested at angles of attack of -8 to +4 degrees and sideslip angles of -4 to +4 degrees. High precision instrumentation was used to acquire pressure data at discrete Mach numbers ranging from 0.6 to 1.55. Pressure coefficient uncertainties were estimated at less than 0.0020. Data is given in graphical and tabular form.

  14. Results of the space shuttle vehicle ascent air data system probe calibration test using a 0.07-scale external tank forebody model (68T) in the AEDC 16-foot transonic wind tunnel (IA-310), volume 2

    NASA Technical Reports Server (NTRS)

    Collette, J. G. R.

    1991-01-01

    A recalibration of the Space Shuttle Vehicle Ascent Air Data System probe was conducted in the Arnold Engineering and Development Center (AEDC) transonic wind tunnel. The purpose was to improve on the accuracy of the previous calibration in order to reduce the existing uncertainties in the system. A probe tip attached to a 0.07-scale External Tank Forebody model was tested at angles of attack of -8 to +4 degrees and sideslip angles of -4 to +4 degrees. High precision instrumentation was used to acquire pressure data at discrete Mach numbers ranging from 0.6 to 1.55. Pressure coefficient uncertainties were estimated at less than 0.0020. Additional information is given in tabular form.

  15. Optical probe

    DOEpatents

    Hencken, Kenneth; Flower, William L.

    1999-01-01

    A compact optical probe is disclosed particularly useful for analysis of emissions in industrial environments. The instant invention provides a geometry for optically-based measurements that allows all optical components (source, detector, rely optics, etc.) to be located in proximity to one another. The geometry of the probe disclosed herein provides a means for making optical measurements in environments where it is difficult and/or expensive to gain access to the vicinity of a flow stream to be measured. Significantly, the lens geometry of the optical probe allows the analysis location within a flow stream being monitored to be moved while maintaining optical alignment of all components even when the optical probe is focused on a plurality of different analysis points within the flow stream.

  16. Contrasting strike-slip motions on thrust and normal faults: Implications for space-geodetic monitoring of surface deformation

    NASA Astrophysics Data System (ADS)

    Hampel, Andrea; Li, Tao; Maniatis, Georgios

    2013-04-01

    emphasizes that understanding fault-parallel slip components and associated surface displacements is essential for inferring regional deformation patterns from space-geodetic and fault-slip data. References: Cheloni, D., N. D'Agostino, E. D'Anastasio, A. Avallone, S. Mantenuto, R. Giuliani, M. Mattone, S. Calcaterra, P. Gambino, D. Dominici, F. Radicioni, G. Fastellini (2010) Coseismic and initial post-seismic slip of the 2009 Mw 6.3 L'Aquila earthquake, Italy, from GPS measurements: Geophysical Journal International, 181, 1539-1546. Hampel, A., T. Li, G. Maniatis (in press) Contrasting strike-slip motions on thrust and normal faults: Implications for space-geodetic monitoring of surface deformation: Geology. Hsu, Y.-J., S.-B Yu, H.-Y. Chen (2009) Coseismic and postseismic deformation associated with the 2003 Chengkung, Taiwan, earthquake: Geophysical Journal International, 176, 420-430. Jackson, J.A., J. Gagnepain, G. Houseman, G.C.P. King, P. Papadimitriou, C. Soufleris, J. Virieux (1982) Seismicity, normal faulting, and the geomorphological development of the Gulf of Corinth (Greece): The Corinth earthquakes of February and March 1981: Earth and Planetary Science Letters, 57, 377-397. Roberts, G.P., I. Koukouvelas (1996) Structural and seismological segmentation of the Gulf of Corinth fault system: Implications for models of fault growth: Annali di Geofisica, 39, 619-646. Serpelloni, E., L. Anderlini, M.E. Belardinelli (2012) Fault geometry, coseismic-slip distribution and Coulomb stress change associated with the 2009 April 6, Mw 6.3, L'Aquila earthquake from inversion of GPS displacements: Geophysical Journal International, 188, 473-489.

  17. Noninvariance of space- and time-scale ranges under a Lorentz Transformation and the implications for the study of relativistic interactions.

    PubMed

    Vay, J-L

    2007-03-30

    We present an analysis which shows that the ranges of space and time scales spanned by a system are not invariant under Lorentz transformation. This implies the existence of a frame of reference which minimizes an aggregate measure of the range of space and time scales. Such a frame is derived, for example, for the following cases: free electron laser, laser-plasma accelerator, and particle beams interacting with electron clouds. The implications for experimental, theoretical, and numerical studies are discussed. The most immediate relevance is the reduction by orders of magnitude in computer simulation run times for such systems.

  18. On the non-invariance of space and time scale ranges under Lorentztransformation, and its implications for the study of relativisticinteractions

    SciTech Connect

    Vay, J.-L.

    2007-01-16

    We present an analysis which shows that the ranges of space and time scales spanned by a system are not invariant under the Lorentz transformation. This implies the existence of a frame of reference which minimizes an aggregate measure of the range of space and time scales. Such a frame is derived for example cases: free electron laser, laser-plasma accelerator, and particle beam interacting with electron clouds. Implications for experimental, theoretical and numerical studies are discussed. The most immediate relevance is the reduction by orders of magnitude in computer simulation run times for such systems.

  19. Noninvariance of Space and Time Scale Ranges under a Lorentz Transformation and the Implications for the Numerical Study of Relativistic Systems

    SciTech Connect

    Vay, J.-L.; Vay, J.-L.

    2007-11-12

    We present an analysis which shows that the ranges of space and time scales spanned by a system are not invariant under the Lorentz transformation. This implies the existence of a frame of reference which minimizes an aggregate measure of the range of space and time scales. Such a frame is derived for example cases: free electron laser, laser-plasma accelerator, and particle beam interacting with electron clouds. Implications for experimental, theoretical and numerical studies are discussed. The most immediate relevance is the reduction by orders of magnitude in computer simulation run times for such systems.

  20. Noninvariance of Space- and Time-Scale Ranges under a Lorentz Transformation and the Implications for the Study of Relativistic Interactions

    SciTech Connect

    Vay, J.-L.

    2007-03-30

    We present an analysis which shows that the ranges of space and time scales spanned by a system are not invariant under Lorentz transformation. This implies the existence of a frame of reference which minimizes an aggregate measure of the range of space and time scales. Such a frame is derived, for example, for the following cases: free electron laser, laser-plasma accelerator, and particle beams interacting with electron clouds. The implications for experimental, theoretical, and numerical studies are discussed. The most immediate relevance is the reduction by orders of magnitude in computer simulation run times for such system000.

  1. A review of the findings of the plasma diagnostic package and associated laboratory experiments: Implications of large body/plasma interactions for future space technology

    NASA Technical Reports Server (NTRS)

    Murphy, Gerald B.; Lonngren, Karl E.

    1986-01-01

    The discoveries and experiments of the Plasma Diagnostic Package (PDP) on the OSS 1 and Spacelab 2 missions are reviewed, these results are compared with those of other space and laboratory experiments, and the implications for the understanding of large body interactions in a low Earth orbit (LEO) plasma environment are discussed. First a brief review of the PDP investigation, its instrumentation and experiments is presented. Next a summary of PDP results along with a comparison of those results with similar space or laboratory experiments is given. Last of all the implications of these results in terms of understanding fundamental physical processes that take place with large bodies in LEO is discussed and experiments to deal with these vital questions are suggested.

  2. A highly selective space-folded photo-induced electron transfer fluorescent probe for carbonic anhydrase isozymes IX and its applications for biological imaging.

    PubMed

    Zhang, Shenyi; Yang, Chunmei; Lu, Weiqiang; Huang, Jin; Zhu, Weiping; Li, Honglin; Xu, Yufang; Qian, Xuhong

    2011-08-07

    The first highly selective and sensitive fluorescent probe Z1 for detection of carbonic anhydrase IX (CA IX) over isoforms CA I and CA II was developed. As demonstrated, Z1 worked effectively in both enzymatic systems and living hypoxia cells.

  3. Multispectral imaging probe

    DOEpatents

    Sandison, D.R.; Platzbecker, M.R.; Descour, M.R.; Armour, D.L.; Craig, M.J.; Richards-Kortum, R.

    1999-07-27

    A multispectral imaging probe delivers a range of wavelengths of excitation light to a target and collects a range of expressed light wavelengths. The multispectral imaging probe is adapted for mobile use and use in confined spaces, and is sealed against the effects of hostile environments. The multispectral imaging probe comprises a housing that defines a sealed volume that is substantially sealed from the surrounding environment. A beam splitting device mounts within the sealed volume. Excitation light is directed to the beam splitting device, which directs the excitation light to a target. Expressed light from the target reaches the beam splitting device along a path coaxial with the path traveled by the excitation light from the beam splitting device to the target. The beam splitting device directs expressed light to a collection subsystem for delivery to a detector. 8 figs.

  4. Multispectral imaging probe

    SciTech Connect

    Sandison, D.R.; Platzbecker, M.R.; Descour, M.R.; Armour, D.L.; Craig, M.J.; Richards-Kortum, R.

    1999-07-27

    A multispectral imaging probe delivers a range of wavelengths of excitation light to a target and collects a range of expressed light wavelengths. The multispectral imaging probe is adapted for mobile use and use in confined spaces, and is sealed against the effects of hostile environments. The multispectral imaging probe comprises a housing that defines a sealed volume that is substantially sealed from the surrounding environment. A beam splitting device mounts within the sealed volume. Excitation light is directed to the beam splitting device, which directs the excitation light to a target. Expressed light from the target reaches the beam splitting device along a path coaxial with the path traveled by the excitation light from the beam splitting device to the target. The beam splitting device directs expressed light to a collection subsystem for delivery to a detector. 8 figs.

  5. Multispectral imaging probe

    SciTech Connect

    Sandison, David R.; Platzbecker, Mark R.; Descour, Michael R.; Armour, David L.; Craig, Marcus J.; Richards-Kortum, Rebecca

    1999-01-01

    A multispectral imaging probe delivers a range of wavelengths of excitation light to a target and collects a range of expressed light wavelengths. The multispectral imaging probe is adapted for mobile use and use in confined spaces, and is sealed against the effects of hostile environments. The multispectral imaging probe comprises a housing that defines a sealed volume that is substantially sealed from the surrounding environment. A beam splitting device mounts within the sealed volume. Excitation light is directed to the beam splitting device, which directs the excitation light to a target. Expressed light from the target reaches the beam splitting device along a path coaxial with the path traveled by the excitation light from the beam splitting device to the target. The beam splitting device directs expressed light to a collection subsystem for delivery to a detector.

  6. Molecular cytogenetic analysis of Inv Dup(15) chromosomes, using probes specific for the Pradar-Willi/Angelman syndrome region: Clinical implications

    SciTech Connect

    Leana-Cox, J. ); Jenkins, L. ); Palmer, C.G.; Plattner, R. ); Sheppard, L. ); Flejter, W.L. ); Zackowski, J. ); Tsien, F. ); Schwartz, S. )

    1994-05-01

    Twenty-seven cases of inverted duplications of chromosome 15 (inv dup[15]) were investigated by FISH with two DNA probes specific for the Prader-Willi syndrome/Angelman syndrome (PWS/AS) region on proximal 15q. Sixteen of the marker chromosomes displayed two copies of each probe, while in the remaining 11 markers no hybridization was observed. A significant association was found between the presence of this region and an abnormal phenotype (P<.01). This is the largest study to date of inv dup(15) chromosomes, that uses molecular cytogenetic methods and is the first to report a significant association between the presence of a specific chromosomal region in such markers and an abnormal phenotype. 30 refs., 1 fig., 4 tabs.

  7. In vivo and in vitro study of radio-frequency application with a new long linear probe: implication for the maze operation.

    PubMed

    Shimoike, E; Kaji, Y; Ueda, N; Maruyama, T; Kanaya, S; Niho, Y

    2000-07-01

    The maze operation for atrial fibrillation is effective but highly invasive. We tested, both in vitro and in vivo, a new technique for creating long linear atrial lesions with a custom-made, 25-mm long, stainless-steel, linear probe and a corresponding 500-kHz generator for assistance in the maze operation. In the in vitro study with the isolated canine atria, the power of the delivered radio-frequency energy and the saline irrigating flow rate were changed independently, and the sizes of the lesions were measured. In the in vivo study radio-frequency energy was delivered to 4 portions (ie, the smooth and trabeculated portions of the right and left atria). The sizes of the lesions were measured, and the histologic features of the lesions were examined. Electrical isolation of the right atrial appendage from the remaining right atrium was attempted by using this linear probe. In the in vitro study the size of the lesion became larger as the delivered power was increased, although the lesion was limited when the flow rate was high. In the in vivo study the size of the lesion was equal at the 4 different sites. Histologic examinations demonstrated linear and transmural lesions, and electrophysiologic examinations revealed conduction block between the right atrial appendage and the remaining right atrium. The new original long linear probe was effective for creating transmural linear atrial lesions with the irrigation method, presenting the possibility of an intraoperative technique that mimics the maze procedure.

  8. Constructing Space

    NASA Astrophysics Data System (ADS)

    Henderson, Austin

    This chapter chronicles the growth of the author's understanding of Media Space through his 20-year experience with coupling spaces, using video. It is a “technology-first” understanding of the construction of space. Key ideas from research studies and practice are presented, and contrasts with other genres of communication are made. The implications for distributed collaboration are explored.

  9. Auroral Spatial Structures Probe Sub-Orbital Mission Preliminary Results

    NASA Astrophysics Data System (ADS)

    Pratt, J.; Swenson, C.; Martineau, R. J.; Fish, C. S.; Conde, M.; Hampton, D.; Crowley, G.

    2015-12-01

    The NASA Auroral Spatial Structures Probe, 49.002, was launched January 28, 2015 from the Poker Flat Research Range into active aurora over the northern coast of Alaska. The primary objective of this mission was to determine the contribution of small spatial and temporal scale fluctuations of the electric fields to the larger-scale energy deposition processes associated with the aurora. The Auroral Spatial Structures Probe Sub-Orbital Mission consisted of a formation of 7 spacecraft (a main payload with 6 deployable sub-payloads) designed for multiple temporally spaced co-located measurements of electric and magnetic fields in the earth's ionosphere. The mission was able to make observations at a short time scale and small spatial scale convergence that is unobservable by either satellite or ground-based observations. The payloads included magnetometers, electric field double probes, and Langmuir probes as well as a sweeping impedance probe on the main payload. We present here preliminary results from the measurements taken that hint at the underlying spatial structure of the currents and energy deposition in the aurora. The Poynting flux derived from the observations is shown and implications are discussed in terms of the contribution of small spatial scale, rapid temporal scale fluctuations in the currents that deposit energy in the auroral region. Funding provided by NASA Grants NNX11AE23G and NNX13AN20A.

  10. Charged Kaon interferometric probes of space-time evolution in Au+Au collisions at sqrt[S(NN)]=200 GeV.

    PubMed

    Afanasiev, S; Aidala, C; Ajitanand, N N; Akiba, Y; Alexander, J; Al-Jamel, A; Aoki, K; Aphecetche, L; Armendariz, R; Aronson, S H; Averbeck, R; Awes, T C; Azmoun, B; Babintsev, V; Baldisseri, A; Barish, K N; Barnes, P D; Bassalleck, B; Bathe, S; Batsouli, S; Baublis, V; Bauer, F; Bazilevsky, A; Belikov, S; Bennett, R; Berdnikov, Y; Bjorndal, M T; Boissevain, J G; Borel, H; Boyle, K; Brooks, M L; Brown, D S; Bucher, D; Buesching, H; Bumazhnov, V; Bunce, G; Burward-Hoy, J M; Butsyk, S; Campbell, S; Chai, J-S; Chernichenko, S; Chiba, J; Chi, C Y; Chiu, M; Choi, I J; Chujo, T; Cianciolo, V; Cleven, C R; Cobigo, Y; Cole, B A; Comets, M P; Constantin, P; Csanád, M; Csörgo, T; Dahms, T; Das, K; David, G; Delagrange, H; Denisov, A; d'Enterria, D; Deshpande, A; Desmond, E J; Dietzsch, O; Dion, A; Drachenberg, J L; Drapier, O; Drees, A; Dubey, A K; Durum, A; Dzhordzhadze, V; Efremenko, Y V; Egdemir, J; Enokizono, A; En'yo, H; Espagnon, B; Esumi, S; Fields, D E; Fleuret, F; Fokin, S L; Forestier, B; Fraenkel, Z; Frantz, J E; Franz, A; Frawley, A D; Fukao, Y; Fung, S-Y; Gadrat, S; Gastineau, F; Germain, M; Glenn, A; Gonin, M; Gosset, J; Goto, Y; Granier de Cassagnac, R; Grau, N; Greene, S V; Grosse Perdekamp, M; Gunji, T; Gustafsson, H-A; Hachiya, T; Hadj Henni, A; Haggerty, J S; Hagiwara, M N; Hamagaki, H; Harada, H; Hartouni, E P; Haruna, K; Harvey, M; Haslum, E; Hasuko, K; Hayano, R; Heffner, M; Hemmick, T K; Heuser, J M; He, X; Hiejima, H; Hill, J C; Hobbs, R; Holmes, M; Holzmann, W; Homma, K; Hong, B; Horaguchi, T; Hur, M G; Ichihara, T; Imai, K; Inaba, M; Isenhower, D; Isenhower, L; Ishihara, M; Isobe, T; Issah, M; Isupov, A; Jacak, B V; Jia, J; Jin, J; Jinnouchi, O; Johnson, B M; Joo, K S; Jouan, D; Kajihara, F; Kametani, S; Kamihara, N; Kaneta, M; Kang, J H; Kawagishi, T; Kazantsev, A V; Kelly, S; Khanzadeev, A; Kim, D J; Kim, E; Kim, Y-S; Kinney, E; Kiss, A; Kistenev, E; Kiyomichi, A; Klein-Boesing, C; Kochenda, L; Kochetkov, V; Komkov, B; Konno, M; Kotchetkov, D; Kozlov, A; Kroon, P J; Kunde, G J; Kurihara, N; Kurita, K; Kweon, M J; Kwon, Y; Kyle, G S; Lacey, R; Lajoie, J G; Lebedev, A; Le Bornec, Y; Leckey, S; Lee, D M; Lee, M K; Leitch, M J; Leite, M A L; Lim, H; Litvinenko, A; Liu, M X; Li, X H; Maguire, C F; Makdisi, Y I; Malakhov, A; Malik, M D; Manko, V I; Masui, H; Matathias, F; McCain, M C; McGaughey, P L; Miake, Y; Miller, T E; Milov, A; Mioduszewski, S; Mishra, G C; Mitchell, J T; Morrison, D P; Moss, J M; Moukhanova, T V; Mukhopadhyay, D; Murata, J; Nagamiya, S; Nagata, Y; Nagle, J L; Naglis, M; Nakamura, T; Newby, J; Nguyen, M; Norman, B E; Nouicer, R; Nyanin, A S; Nystrand, J; O'Brien, E; Ogilvie, C A; Ohnishi, H; Ojha, I D; Okada, H; Okada, K; Omiwade, O O; Oskarsson, A; Otterlund, I; Ozawa, K; Pal, D; Palounek, A P T; Pantuev, V; Papavassiliou, V; Park, J; Park, W J; Pate, S F; Pei, H; Peng, J-C; Pereira, H; Peresedov, V; Peressounko, D Yu; Pinkenburg, C; Pisani, R P; Purschke, M L; Purwar, A K; Qu, H; Rak, J; Ravinovich, I; Read, K F; Reuter, M; Reygers, K; Riabov, V; Riabov, Y; Roche, G; Romana, A; Rosati, M; Rosendahl, S S E; Rosnet, P; Rukoyatkin, P; Rykov, V L; Ryu, S S; Sahlmueller, B; Saito, N; Sakaguchi, T; Sakai, S; Samsonov, V; Sato, H D; Sato, S; Sawada, S; Semenov, V; Seto, R; Sharma, D; Shea, T K; Shein, I; Shibata, T-A; Shigaki, K; Shimomura, M; Shohjoh, T; Shoji, K; Sickles, A; Silva, C L; Silvermyr, D; Sim, K S; Singh, C P; Singh, V; Skutnik, S; Smith, W C; Soldatov, A; Soltz, R A; Sondheim, W E; Sorensen, S P; Sourikova, I V; Staley, F; Stankus, P W; Stenlund, E; Stepanov, M; Ster, A; Stoll, S P; Sugitate, T; Suire, C; Sullivan, J P; Sziklai, J; Tabaru, T; Takagi, S; Takagui, E M; Taketani, A; Tanaka, K H; Tanaka, Y; Tanida, K; Tannenbaum, M J; Taranenko, A; Tarján, P; Thomas, T L; Togawa, M; Tojo, J; Torii, H; Towell, R S; Tram, V-N; Tserruya, I; Tsuchimoto, Y; Tuli, S K; Tydesjö, H; Tyurin, N; Vale, C; Valle, H; van Hecke, H W; Velkovska, J; Vértesi, R; Vinogradov, A A; Vznuzdaev, E; Wagner, M; Wang, X R; Watanabe, Y; Wessels, J; White, S N; Willis, N; Winter, D; Woody, C L; Wysocki, M; Xie, W; Yanovich, A; Yokkaichi, S; Young, G R; Younus, I; Yushmanov, I E; Zajc, W A; Zaudtke, O; Zhang, C; Zimányi, J; Zolin, L

    2009-10-02

    Bose-Einstein correlations of charged kaons are used to probe Au+Au collisions at sqrt[S(NN)]=200 GeV and are compared to charged pion probes, which have a larger hadronic scattering cross section. Three-dimensional Gaussian source radii are extracted, along with a one-dimensional kaon emission source function. The centrality dependences of the three Gaussian radii are well described by a single linear function of N(part)1/3 with a zero intercept. Imaging analysis shows a deviation from a Gaussian tail at r greater than or approximately equal to 10 fm, although the bulk emission at lower radius is well described by a Gaussian. The presence of a non-Gaussian tail in the kaon source reaffirms that the particle emission region in a heavy-ion collision is extended, and that similar measurements with pions are not solely due to the decay of long-lived resonances.

  11. Preliminary estimation of color inhomogeneities on the surface of Venus according to the television images obtained by the VENERA-13 and VENERA-14 automated space probes

    NASA Technical Reports Server (NTRS)

    Shkuratov, Yu. G.; Kreslavskiy, M. A.; Bazilevskiy, A. T.

    1987-01-01

    Digital processing of images obtained by the Venera 13 and Venera 14 probes led to the discovery of faint color differences of some areas of the observed surface. Maximum color differences were observed in the right part of 14-1 panorama. Color anomaly is associated with the bedrock outcrop having slightly higher albedo than the surrounding. Possible causes of the discovered color differences are discussed.

  12. Study of photoemission and work function of large surface areas, phase 3, phase 4. [wavelength dependences of photoelectric space probe materials

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The photoemission of materials which might be used in probe measurements of the exo-atmospheric electric field is considered by evaluating the wavelength dependence of their photoelectric yield for eleven elements over the range 800 to 3200 A. Yield data for zinc, copper beryllium, platinum, cadmium, graphite, carbon, gold, silver, tantalum, and tungsten show that copper-beryllium is a preferred material. Silver has one of the highest photoemissions when exposed to solar radiation.

  13. Preliminary estimation of color inhomogeneities on the surface of Venus according to the television images obtained by the VENERA-13 and VENERA-14 automated space probes

    NASA Technical Reports Server (NTRS)

    Shkuratov, Yu. G.; Kreslavskiy, M. A.; Bazilevskiy, A. T.

    1987-01-01

    Digital processing of images obtained by the Venera 13 and Venera 14 probes led to the discovery of faint color differences of some areas of the observed surface. Maximum color differences were observed in the right part of 14-1 panorama. Color anomaly is associated with the bedrock outcrop having slightly higher albedo than the surrounding. Possible causes of the discovered color differences are discussed.

  14. Droplet monitoring probe

    NASA Technical Reports Server (NTRS)

    Baughman, J. R.; Thys, P. C.

    1973-01-01

    A droplet monitoring system is disclosed for analysis of mixed-phase fluid flow in development of gas turbines. The system uses a probe comprising two electrical wires spaced a known distance apart and connected at one end to means for establishing a dc potential between the wires. A drop in the fluid stream momentarily contacting both wires simultaneously causes and electrical signal which is amplified, detected and counted.

  15. RECONSTRUCTING CORONAL MASS EJECTIONS WITH COORDINATED IMAGING AND IN SITU OBSERVATIONS: GLOBAL STRUCTURE, KINEMATICS, AND IMPLICATIONS FOR SPACE WEATHER FORECASTING

    SciTech Connect

    Liu Ying; Luhmann, Janet G.; Lin, Robert P.; Bale, Stuart D.; Thernisien, Arnaud; Vourlidas, Angelos; Davies, Jackie A.

    2010-10-20

    We reconstruct the global structure and kinematics of coronal mass ejections (CMEs) using coordinated imaging and in situ observations from multiple vantage points. A forward modeling technique, which assumes a rope-like morphology for CMEs, is used to determine the global structure (including orientation and propagation direction) from coronagraph observations. We reconstruct the corresponding structure from in situ measurements at 1 AU with the Grad-Shafranov method, which gives the flux-rope orientation, cross section, and a rough knowledge of the propagation direction. CME kinematics (propagation direction and radial distance) during the transit from the Sun to 1 AU are studied with a geometric triangulation technique, which provides an unambiguous association between solar observations and in situ signatures; a track fitting approach is invoked when data are available from only one spacecraft. We show how the results obtained from imaging and in situ data can be compared by applying these methods to the 2007 November 14-16 and 2008 December 12 CMEs. This merged imaging and in situ study shows important consequences and implications for CME research as well as space weather forecasting: (1) CME propagation directions can be determined to a relatively good precision as shown by the consistency between different methods; (2) the geometric triangulation technique shows a promising capability to link solar observations with corresponding in situ signatures at 1 AU and to predict CME arrival at the Earth; (3) the flux rope within CMEs, which has the most hazardous southward magnetic field, cannot be imaged at large distances due to expansion; (4) the flux-rope orientation derived from in situ measurements at 1 AU may have a large deviation from that determined by coronagraph image modeling; and (5) we find, for the first time, that CMEs undergo a westward migration with respect to the Sun-Earth line at their acceleration phase, which we suggest is a universal

  16. Near-Field Photothermal Heating with a Plasmonic Nanofocusing Probe

    NASA Astrophysics Data System (ADS)

    Chen, Xiang; Dong, Biqing; Balogun, Oluwaseyi

    2016-03-01

    Noble metal nanostructures support plasmon resonances—collective oscillation of charge carriers at optical frequencies—and serve as effective tools to create bright light sources at the nanoscale. These sources are useful in broad application areas including, super-resolution imaging and spectroscopy, nanolithography, and near-field optomechanical transducers. The feasibility of these applications relies on efficient conversion of free-space propagating light to plasmons. Recently, we demonstrated a hybrid nanofocusing scheme for efficient coupling of light to plasmons at the apex of a scanning probe. In the approach, free-space light is coupled to propagating surface plasmon polaritons (SPPs) on the tapered shaft of the scanning probe. The SPPs propagate adiabatically towards the probe tip where they are coupled to localized plasmons (LSPs). The nanofocusing scheme was explored in a near-field scanning optical microscope for super-resolution imaging, near-field transduction of nanomechanical vibrations, and local detection of ultrasound. Owing to the strong concentration of light at the probe, significant heating of the tip and a sample positioned in the optical near-field is expected. This paper investigates the local heating produced by the plasmonic nanofocusing probe under steady-state conditions using the tip-enhanced Raman scattering approach. In addition, a finite element model is explored to study the coupling of free propagating light to LSPs, and to estimate the temperature rise expected in a halfspace heated by absorption of the LSPs. This study has implications for exploring the plasmonic nanofocusing probe in heat-assisted nanofabrication and fundamental studies of nanoscale heat transport in materials.

  17. Artist's Concept of Gravity Probe-B

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Gravity Probe-B (GP-B) is the relativity experiment being developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies -- technologies that are already enlivening other branches of science and engineering. Scheduled for launch in 2003 and managed for NASA by Marshall Space Flight Center, development of the GP-B is the responsibility of Stanford University, with major subcontractor Lockheed Martin Corporation.

  18. Artist's Concept of Gravity Probe-B

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Gravity Probe-B (GP-B) is the relativity experiment being developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies -- technologies that are already enlivening other branches of science and engineering. Scheduled for launch in 2003 and managed for NASA by the Marshall Space Flight Center, development of GP-B is the responsibility of Stanford University, with major subcontractor Lockheed Martin Corporation.

  19. Gravity Probe B Number 4 Gyro Inspected

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The Gravity Probe B (GP-B) is the relativity experiment developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. In this photograph, Stanford engineer, Chris Gray, is inspecting the number 4 gyro under monochromatic light. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies that are already enlivening other branches of science and engineering. Launched April 20, 2004 , the GP-B program was managed for NASA by the Marshall Space Flight Center. Development of the GP-B is the responsibility of Stanford University along with major subcontractor Lockheed Martin Corporation. (Image credit to Russ Leese, Stanford University.)

  20. Artist's Concept of Gravity Probe-B

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Gravity Probe-B (GP-B) is the relativity experiment being developed at Stanford University to test two extraordinary predictions of Albert Einstein's general theory of relativity. The experiment will measure, very precisely, the expected tiny changes in the direction of the spin axes of four gyroscopes contained in an Earth-orbiting satellite at a 400-mile altitude. So free are the gyroscopes from disturbance that they will provide an almost perfect space-time reference system. They will measure how space and time are very slightly warped by the presence of the Earth, and, more profoundly, how the Earth's rotation very slightly drags space-time around with it. These effects, though small for the Earth, have far-reaching implications for the nature of matter and the structure of the Universe. GP-B is among the most thoroughly researched programs ever undertaken by NASA. This is the story of a scientific quest in which physicists and engineers have collaborated closely over many years. Inspired by their quest, they have invented a whole range of technologies -- technologies that are already enlivening other branches of science and engineering. Scheduled for launch in 2003 and managed for NASA by Marshall Space Flight Center, development of GP-B is the responsibility of Stanford University, with major subcontractor Lockheed Martin Corporation.