The Effect of Temperature on Faceplate/Core Delamination in Composite/Titanium Sandwich Plates

NASA Technical Reports Server (NTRS)

Liechti, Kenneth M.; Marton, Balazs

2000-01-01

A study was made of the delamination behavior of sandwich beams made of titanium core bonded to face-plates that consisted of carbon fiber reinforced polymer composite. Nominally mode I behavior was considered at 23C and 180C, by making use of a specially reinforced double cantilever (DCB) specimens. The toughness of the bond between the faceplate and the core was determined on the basis of a beam on elastic foundation analysis. The specimen compliance, and toughness were all independent of temperature in these relatively short-term experiments. The fracture mechanism showed temperature dependence, due to the hygrothermal sensitivity of the adhesive.

Technology-Aided Instruction and Intervention for Students with ASD: A Meta-Analysis Using Novel Methods of Estimating Effect Sizes for Single-Case Research

ERIC Educational Resources Information Center

Barton, Erin E.; Pustejovsky, James E.; Maggin, Daniel M.; Reichow, Brian

2017-01-01

The adoption of methods and strategies validated through rigorous, experimentally oriented research is a core professional value of special education. We conducted a systematic review and meta-analysis examining the experimental literature on Technology-Aided Instruction and Intervention (TAII) using research identified as part of the National…

A Vehicle for Bivariate Data Analysis

ERIC Educational Resources Information Center

Roscoe, Matt B.

2016-01-01

Instead of reserving the study of probability and statistics for special fourth-year high school courses, the Common Core State Standards for Mathematics (CCSSM) takes a "statistics for all" approach. The standards recommend that students in grades 6-8 learn to summarize and describe data distributions, understand probability, draw…

National Sexuality Education Standards: Core Content and Skills, K-12. A Special Publication of the Journal of School Health. Special Report

ERIC Educational Resources Information Center

American School Health Association (NJ1), 2012

2012-01-01

The goal of this paper, "National Sexuality Education Standards: Core Content and Skills, K-12," is to provide clear, consistent and straightforward guidance on the "essential minimum, core content" for sexuality education that is developmentally and age-appropriate for students in grades K-12. The development of these standards is a result of an…

Evaluation of residual oil saturation after waterflood in a carbonate reservoir

DOE Office of Scientific and Technical Information (OSTI.GOV)

Verma, M.K.; Boucherit, M.; Bouvier, L.

Four different approaches, including special core analysis (SCAL), log-inject-log, thermal-decay-time (TDT) logs, and material balance, were used to narrow the range of residual oil saturation (ROS) after waterflood, S[sub orw], in a carbonate reservoir in Qatar to between 23% and 27%. An equation was developed that relates S[sub orw] with connate-water saturation, S[sub wi], and porosity. This paper presents the results of S[sub orw] determinations with four different techniques: core waterflood followed by centrifuging, log-inject-log, TDT logging, and material balance.

Role of CT scanning in formation evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bergosh, J.L.; Dibona, B.G.

1988-01-01

The use of the computerized tomographic (CT) scanner in formation evaluation of difficult to analyze core samples has moved from the research and development phase to daily, routine use in the core-analysis laboratory. The role of the CT scanner has become increasingly important as geologists try to obtain more representative core material for accurate formation evaluation. The most common problem facing the core analyst when preparing to measure petrophysical properties is the selection of representative and unaltered core samples for routine and special core testing. Recent data have shown that heterogeneous reservoir rock can be very difficult, if not impossible,more » to assess correctly when using standard core examination procedures, because many features, such as fractures, are not visible on the core surface. Another problem is the invasion of drilling mud into the core sample. Flushing formation oil and water from the core can greatly alter the saturation and distribution of fluids and lead to serious formation evaluation problems. Because the quality and usefulness of the core date are directly tied to proper sample selection, it has become imperative that the CT scanner be used whenever possible.« less

A Core Knowledge Architecture of Visual Working Memory

ERIC Educational Resources Information Center

Wood, Justin N.

2011-01-01

Visual working memory (VWM) is widely thought to contain specialized buffers for retaining spatial and object information: a "spatial-object architecture." However, studies of adults, infants, and nonhuman animals show that visual cognition builds on core knowledge systems that retain more specialized representations: (1) spatiotemporal…

Special Education Teachers' Knowledge and Use of Brain-Based Teaching, Common Core State Standards, Formative Feedback Practices and Instructional Efficacy for the Diverse Learning Needs of Students in High and Low Proficiency Groups

ERIC Educational Resources Information Center

Walker-Thompson, Malasia

2014-01-01

This study examined special education teachers' knowledge and use of: brain-based teaching strategies, Common Core State Standards, formative feedback, and instructional efficacy for diverse students. The study identified the differences amongst special education teachers' responses on the dimensions of brain-based teaching strategies, Common Core…

Opportunities and Challenges of Linking Scientific Core Samples to the Geoscience Data Ecosystem

NASA Astrophysics Data System (ADS)

Noren, A. J.

2016-12-01

Core samples generated in scientific drilling and coring are critical for the advancement of the Earth Sciences. The scientific themes enabled by analysis of these samples are diverse, and include plate tectonics, ocean circulation, Earth-life system interactions (paleoclimate, paleobiology, paleoanthropology), Critical Zone processes, geothermal systems, deep biosphere, and many others, and substantial resources are invested in their collection and analysis. Linking core samples to researchers, datasets, publications, and funding agencies through registration of globally unique identifiers such as International Geo Sample Numbers (IGSNs) offers great potential for advancing several frontiers. These include maximizing sample discoverability, access, reuse, and return on investment; a means for credit to researchers; and documentation of project outputs to funding agencies. Thousands of kilometers of core samples and billions of derivative subsamples have been generated through thousands of investigators' projects, yet the vast majority of these samples are curated at only a small number of facilities. These numbers, combined with the substantial similarity in sample types, make core samples a compelling target for IGSN implementation. However, differences between core sample communities and other geoscience disciplines continue to create barriers to implementation. Core samples involve parent-child relationships spanning 8 or more generations, an exponential increase in sample numbers between levels in the hierarchy, concepts related to depth/position in the sample, requirements for associating data derived from core scanning and lithologic description with data derived from subsample analysis, and publications based on tens of thousands of co-registered scan data points and thousands of analyses of subsamples. These characteristics require specialized resources for accurate and consistent assignment of IGSNs, and a community of practice to establish norms, workflows, and infrastructure to support implementation.

Common Core Expertise for Special Education Teachers: What Do Special Education Administrators Think Is Important?

ERIC Educational Resources Information Center

Van Boxtel, Joanne M.

2017-01-01

The Common Core State Standards (CCSS) have been described as the next chapter in American education with the promise to deliver "fewer, clearer, and higher" standards aimed at preparing "all" students for college "and" career (Rothman, 2013). Though CCSS articulates minimum expectations for what college and…

34 CFR 300.18 - Highly qualified special education teachers.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Highly qualified special education teachers. 300.18... SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE... special education teachers. (a) Requirements for special education teachers teaching core academic...

Behavior of composite sandwich panels with several core designs at different impact velocities

NASA Astrophysics Data System (ADS)

Jiga, Gabriel; Stamin, Ştefan; Dinu, Gabriela

2018-02-01

A sandwich composite represents a special class of composite materials that is manufactured by bonding two thin but stiff faces to a low density and low strength but thick core. The distance between the skins given by the core increases the flexural modulus of the panel with a low mass increase, producing an efficient structure able to resist at flexural and buckling loads. The strength of sandwich panels depends on the size of the panel, skins material and number or density of the cells within it. Sandwich composites are used widely in several industries, such as aerospace, automotive, medical and leisure industries. The behavior of composite sandwich panels with different core designs under different impact velocities are analyzed in this paper by numerical simulations performed on sandwich panels. The modeling was done in ANSYS and the analysis was performed through LS-DYNA.

Magnetic resonance imaging in laboratory petrophysical core analysis

NASA Astrophysics Data System (ADS)

Mitchell, J.; Chandrasekera, T. C.; Holland, D. J.; Gladden, L. F.; Fordham, E. J.

2013-05-01

Magnetic resonance imaging (MRI) is a well-known technique in medical diagnosis and materials science. In the more specialized arena of laboratory-scale petrophysical rock core analysis, the role of MRI has undergone a substantial change in focus over the last three decades. Initially, alongside the continual drive to exploit higher magnetic field strengths in MRI applications for medicine and chemistry, the same trend was followed in core analysis. However, the spatial resolution achievable in heterogeneous porous media is inherently limited due to the magnetic susceptibility contrast between solid and fluid. As a result, imaging resolution at the length-scale of typical pore diameters is not practical and so MRI of core-plugs has often been viewed as an inappropriate use of expensive magnetic resonance facilities. Recently, there has been a paradigm shift in the use of MRI in laboratory-scale core analysis. The focus is now on acquiring data in the laboratory that are directly comparable to data obtained from magnetic resonance well-logging tools (i.e., a common physics of measurement). To maintain consistency with well-logging instrumentation, it is desirable to measure distributions of transverse (T2) relaxation time-the industry-standard metric in well-logging-at the laboratory-scale. These T2 distributions can be spatially resolved over the length of a core-plug. The use of low-field magnets in the laboratory environment is optimal for core analysis not only because the magnetic field strength is closer to that of well-logging tools, but also because the magnetic susceptibility contrast is minimized, allowing the acquisition of quantitative image voxel (or pixel) intensities that are directly scalable to liquid volume. Beyond simple determination of macroscopic rock heterogeneity, it is possible to utilize the spatial resolution for monitoring forced displacement of oil by water or chemical agents, determining capillary pressure curves, and estimating wettability. The history of MRI in petrophysics is reviewed and future directions considered, including advanced data processing techniques such as compressed sensing reconstruction and Bayesian inference analysis of under-sampled data. Although this review focuses on rock core analysis, the techniques described are applicable in a wider context to porous media in general, such as cements, soils, ceramics, and catalytic materials.

Using special additions to preparation of the moulding mixture for casting steel parts of drive wheel type

NASA Astrophysics Data System (ADS)

Josan, A.; Pinca Bretotean, C.

2015-06-01

The paper presents the possibility of using special additions to the execution of moulding mixtures for steel castings, drive wheel type. Critical analysis of moulding technology leads to the idea that most defects appear due to using improper moulding mixture. Using a improper moulding mixture leads to penetration of steel in moulding mixture, resulting in the formation of adherences, due to inadequate refractarity of the mould and core mixtures. Using only the unique mixture to the moulding leads to increasing consumption of new sand, respectively to the increase of price of piece. Acording to the dates registered in the industrial practice is necessary to use the special additions to obtain the moulding mixtures, carbonaceous materials respectively.

Air-Gapped Structures as Magnetic Elements for Use in Power Processing Systems. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Ohri, A. K.

1977-01-01

Methodical approaches to the design of inductors for use in LC filters and dc-to-dc converters using air gapped magnetic structures are presented. Methods for the analysis and design of full wave rectifier LC filter circuits operating with the inductor current in both the continuous conduction and the discontinuous conduction modes are also described. In the continuous conduction mode, linear circuit analysis techniques are employed, while in the case of the discontinuous mode, the method of analysis requires computer solutions of the piecewise linear differential equations which describe the filter in the time domain. Procedures for designing filter inductors using air gapped cores are presented. The first procedure requires digital computation to yield a design which is optimized in the sense of minimum core volume and minimum number of turns. The second procedure does not yield an optimized design as defined above, but the design can be obtained by hand calculations or with a small calculator. The third procedure is based on the use of specially prepared magnetic core data and provides an easy way to quickly reach a workable design.

Improved transformer-winding method

NASA Technical Reports Server (NTRS)

Mclyman, W. T.

1978-01-01

Proposed technique using special bobbin and fixture to wind copper wire directly on core eliminates need core cut prior to assembly. Application of technique could result in production of quieter core with increased permeability and no localized heating.

Analysis of tracheid development in suppressed-growth Ponderosa Pine using the FPL ring profiler

Treesearch

C. Tim Scott; David W. Vahey

2012-01-01

The Ring Profiler was developed to examine the cross-sectional morphology of wood tracheids in a 12.5-mm core sample. The instrument integrates a specially designed staging apparatus with an optical imaging system to obtain high-contrast, high-resolution images containing about 200-500 tracheids. These images are further enhanced and analyzed to extract tracheid cross-...

75 FR 22816 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Revitalizing Core...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-30

...(c)(4) and (6), Title 5, U.S.C., and the Determination of the Director, Management Analysis and..., PhD, M.P.H., NCIPC/ERPO, CDC, 4770 Buford Highway, NE., M/S F62, Atlanta, Georgia 30341-3724... and Prevention. [FR Doc. 2010-10164 Filed 4-29-10; 8:45 am] BILLING CODE 4163-18-P ...

United States Department of Agriculture/Agricultural Research Service (USDA-ARS) Eastern Regional Research Center Core Technologies

PubMed Central

Nunez, A.; Strahan, G.; Soroka, D.S.; Damert, W.; Needleman, D.

2011-01-01

The Core Technologies (CT) unit, located at the Eastern Regional Research Center (ERRC), is a centralized resource of specialized instrumentation and technologies. Its objective is to provide supplementary research data processing, interpretation, analysis and consultation for a broad range of research programs approved by the Agricultural Research Service (ARS), the in-house research arm of the United States Department of Agriculture. The CT unit is comprised of four research related components: genetic analysis, proteomicsbiopolymers mass spectrometry, electron microscopy, and magnetic resonance spectroscopy (NMR). In addition, the Research Data Systems, the information pipeline of the CT, provides the means to facilitate data distribution to researchers, stakeholders, and the general public. The availability of integrated resource laboratories assures professional and dependable support to the goals of the ARS community.

Addressing Pre-Service Teachers' Understandings and Difficulties with Some Core Concepts in the Special Theory of Relativity

ERIC Educational Resources Information Center

Selcuk, Gamze Sezgin

2011-01-01

The aim of this study is to investigate pre-service teachers' understanding of and difficulties with some core concepts in the special theory of relativity. The pre-service teachers (n = 185) from the Departments of Physics Education and Elementary Science Education at Dokuz Eylul University (in Turkey) participated. Both quantitative and…

Specifying the core network supporting episodic simulation and episodic memory by activation likelihood estimation

PubMed Central

Benoit, Roland G.; Schacter, Daniel L.

2015-01-01

It has been suggested that the simulation of hypothetical episodes and the recollection of past episodes are supported by fundamentally the same set of brain regions. The present article specifies this core network via Activation Likelihood Estimation (ALE). Specifically, a first meta-analysis revealed joint engagement of core network regions during episodic memory and episodic simulation. These include parts of the medial surface, the hippocampus and parahippocampal cortex within the medial temporal lobes, and the lateral temporal and inferior posterior parietal cortices on the lateral surface. Both capacities also jointly recruited additional regions such as parts of the bilateral dorsolateral prefrontal cortex. All of these core regions overlapped with the default network. Moreover, it has further been suggested that episodic simulation may require a stronger engagement of some of the core network’s nodes as wells as the recruitment of additional brain regions supporting control functions. A second ALE meta-analysis indeed identified such regions that were consistently more strongly engaged during episodic simulation than episodic memory. These comprised the core-network clusters located in the left dorsolateral prefrontal cortex and posterior inferior parietal lobe and other structures distributed broadly across the default and fronto-parietal control networks. Together, the analyses determine the set of brain regions that allow us to experience past and hypothetical episodes, thus providing an important foundation for studying the regions’ specialized contributions and interactions. PMID:26142352

34 CFR 300.10 - Core academic subjects.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 2 2012-07-01 2012-07-01 false Core academic subjects. 300.10 Section 300.10 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES General Definitions Used in This Part § 300.10 Core academic subjects. Core academic subjects...

34 CFR 300.10 - Core academic subjects.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true Core academic subjects. 300.10 Section 300.10 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES General Definitions Used in This Part § 300.10 Core academic subjects. Core academic subjects...

34 CFR 300.10 - Core academic subjects.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 2 2013-07-01 2013-07-01 false Core academic subjects. 300.10 Section 300.10 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES General Definitions Used in This Part § 300.10 Core academic subjects. Core academic subjects...

34 CFR 300.10 - Core academic subjects.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 2 2014-07-01 2013-07-01 true Core academic subjects. 300.10 Section 300.10 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND... DISABILITIES General Definitions Used in This Part § 300.10 Core academic subjects. Core academic subjects...

Catalytic performance of M@Ni (M = Fe, Ru, Ir) core-shell nanoparticles towards ammonia decomposition for CO x -free hydrogen production

NASA Astrophysics Data System (ADS)

Chen, Xin; Zhou, Junwei; Chen, Shuangjing; Zhang, Hui

2018-06-01

To reduce the use of precious metals and maintain the catalytic activity for NH3 decomposition reaction, it is an effective way to construct bimetallic nanoparticles with special structures. In this paper, by using density functional theory methods, we investigated NH3 decomposition reaction on three types of core-shell nanoparticles M@Ni (M = Fe, Ru, Ir) with 13 core M atoms and 42 shell Ni atoms. The size of these three particles is about 1 nm. Benefit from alloying with Ru in this nanocluster, Ru@Ni core-shell nanoparticles exhibit catalytic activity comparable to that of single metal Ru, based on the analysis of the adsorption energy and potential energy diagram of NH3 decomposition, as well as N2 desorption processes. However, as for Fe@Ni and Ir@Ni core-shell nanoparticles, their catalytic activities are still unsatisfactory compared to the active metal Ru. In addition, in order to further explain the synergistic effect of bimetallic core-shell nanoparticles, the partial density of states were also calculated. The results show that d-band electrons provided by the core metal are the main factors affecting the entire catalytic process.

Potential microbial contamination during sampling of permafrost soil assessed by tracers

NASA Astrophysics Data System (ADS)

Bang-Andreasen, Toke; Schostag, Morten; Priemé, Anders; Elberling, Bo; Jacobsen, Carsten S.

2017-02-01

Drilling and handling of permanently frozen soil cores without microbial contamination is of concern because contamination e.g. from the active layer above may lead to incorrect interpretation of results in experiments investigating potential and actual microbial activity in these low microbial biomass environments. Here, we present an example of how microbial contamination from active layer soil affected analysis of the potentially active microbial community in permafrost soil. We also present the development and use of two tracers: (1) fluorescent plastic microspheres and (2) Pseudomonas putida genetically tagged with Green Fluorescent Protein production to mimic potential microbial contamination of two permafrost cores. A protocol with special emphasis on avoiding microbial contamination was developed and employed to examine how far microbial contamination can penetrate into permafrost cores. The quantity of tracer elements decreased with depth into the permafrost cores, but the tracers were detected as far as 17 mm from the surface of the cores. The results emphasize that caution should be taken to avoid microbial contamination of permafrost cores and that the application of tracers represents a useful tool to assess penetration of potential microbial contamination into permafrost cores.

Potential microbial contamination during sampling of permafrost soil assessed by tracers.

PubMed

Bang-Andreasen, Toke; Schostag, Morten; Priemé, Anders; Elberling, Bo; Jacobsen, Carsten S

2017-02-23

Drilling and handling of permanently frozen soil cores without microbial contamination is of concern because contamination e.g. from the active layer above may lead to incorrect interpretation of results in experiments investigating potential and actual microbial activity in these low microbial biomass environments. Here, we present an example of how microbial contamination from active layer soil affected analysis of the potentially active microbial community in permafrost soil. We also present the development and use of two tracers: (1) fluorescent plastic microspheres and (2) Pseudomonas putida genetically tagged with Green Fluorescent Protein production to mimic potential microbial contamination of two permafrost cores. A protocol with special emphasis on avoiding microbial contamination was developed and employed to examine how far microbial contamination can penetrate into permafrost cores. The quantity of tracer elements decreased with depth into the permafrost cores, but the tracers were detected as far as 17 mm from the surface of the cores. The results emphasize that caution should be taken to avoid microbial contamination of permafrost cores and that the application of tracers represents a useful tool to assess penetration of potential microbial contamination into permafrost cores.

Potential microbial contamination during sampling of permafrost soil assessed by tracers

PubMed Central

Bang-Andreasen, Toke; Schostag, Morten; Priemé, Anders; Elberling, Bo; Jacobsen, Carsten S.

2017-01-01

Drilling and handling of permanently frozen soil cores without microbial contamination is of concern because contamination e.g. from the active layer above may lead to incorrect interpretation of results in experiments investigating potential and actual microbial activity in these low microbial biomass environments. Here, we present an example of how microbial contamination from active layer soil affected analysis of the potentially active microbial community in permafrost soil. We also present the development and use of two tracers: (1) fluorescent plastic microspheres and (2) Pseudomonas putida genetically tagged with Green Fluorescent Protein production to mimic potential microbial contamination of two permafrost cores. A protocol with special emphasis on avoiding microbial contamination was developed and employed to examine how far microbial contamination can penetrate into permafrost cores. The quantity of tracer elements decreased with depth into the permafrost cores, but the tracers were detected as far as 17 mm from the surface of the cores. The results emphasize that caution should be taken to avoid microbial contamination of permafrost cores and that the application of tracers represents a useful tool to assess penetration of potential microbial contamination into permafrost cores. PMID:28230151

Special methods for aerodynamic-moment calculations from parachute FSI modeling

NASA Astrophysics Data System (ADS)

Takizawa, Kenji; Tezduyar, Tayfun E.; Boswell, Cody; Tsutsui, Yuki; Montel, Kenneth

2015-06-01

The space-time fluid-structure interaction (STFSI) methods for 3D parachute modeling are now at a level where they can bring reliable, practical analysis to some of the most complex parachute systems, such as spacecraft parachutes. The methods include the Deforming-Spatial-Domain/Stabilized ST method as the core computational technology, and a good number of special FSI methods targeting parachutes. Evaluating the stability characteristics of a parachute based on how the aerodynamic moment varies as a function of the angle of attack is one of the practical analyses that reliable parachute FSI modeling can deliver. We describe the special FSI methods we developed for this specific purpose and present the aerodynamic-moment data obtained from FSI modeling of NASA Orion spacecraft parachutes and Japan Aerospace Exploration Agency (JAXA) subscale parachutes.

Fukushima Daiichi Unit 1 Ex-Vessel Prediction: Core Concrete Interaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robb, Kevin R; Farmer, Mitchell; Francis, Matthew W

Lower head failure and corium concrete interaction were predicted to occur at Fukushima Daiichi Unit 1 (1F1) by several different system-level code analyses, including MELCOR v2.1 and MAAP5. Although these codes capture a wide range of accident phenomena, they do not contain detailed models for ex-vessel core melt behavior. However, specialized codes exist for analysis of ex-vessel melt spreading (e.g., MELTSPREAD) and long-term debris coolability (e.g., CORQUENCH). On this basis, an analysis was carried out to further evaluate ex-vessel behavior for 1F1 using MELTSPREAD and CORQUENCH. Best-estimate melt pour conditions predicted by MELCOR v2.1 and MAAP5 were used as input.more » MELTSPREAD was then used to predict the spatially dependent melt conditions and extent of spreading during relocation from the vessel. The results of the MELTSPREAD analysis are reported in a companion paper. This information was used as input for the long-term debris coolability analysis with CORQUENCH.« less

Comparison of laboratory and in-situ measurements of waterflood residual oil saturations for the Cormorant field

DOE Office of Scientific and Technical Information (OSTI.GOV)

van Poelgeest, F.; Niko, H.; Modwid, A.R.

1991-03-01

Shell Expro and Koninklijke/Shell E and P Laboratorium (KSEPL) have been engaged in a multidisciplinary effort to determine the water flood residual oil saturation (ROS) in two principal reservoirs of the Cormorant oil field in the U.K. sector of the North Sea. Data acquisition included special coring and testing. The study, which involved new reservoir-engineering and petrophysical techniques, was aimed at establishing consistent ROS values. This paper reports that reservoir-engineering work centered on reservoir-condition corefloods in the relative-permeability-at-reservoir-conditions (REPARC) apparatus, in which restoration of representative wettability condition was attempted with the aging technique. Aging results in a consistent reduction ofmore » water-wetness of all core samples. The study indicated that ROS values obtained on aged cores at water throughputs of at least 5 PV represented reservoir conditions. The petrophysical part of the study involved ROS estimation from sponge-core analysis and log evaluation.« less

48 CFR 3439.703 - Federal desktop core configuration (FDCC) compatibility.

Code of Federal Regulations, 2014 CFR

2014-10-01

... OF EDUCATION ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Department Requirements for Acquisition of Information Technology 3439.703 Federal desktop core...

48 CFR 3439.703 - Federal desktop core configuration (FDCC) compatibility.

Code of Federal Regulations, 2012 CFR

2012-10-01

... OF EDUCATION ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Department Requirements for Acquisition of Information Technology 3439.703 Federal desktop core...

48 CFR 3439.703 - Federal desktop core configuration (FDCC) compatibility.

Code of Federal Regulations, 2011 CFR

2011-10-01

... OF EDUCATION ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Department Requirements for Acquisition of Information Technology 3439.703 Federal desktop core...

48 CFR 3439.703 - Federal desktop core configuration (FDCC) compatibility.

Code of Federal Regulations, 2013 CFR

2013-10-01

... OF EDUCATION ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Department Requirements for Acquisition of Information Technology 3439.703 Federal desktop core...

SPERT Destructive Test - I on Aluminum, Highly Enriched Plate Type Core

ScienceCinema

None

2018-01-16

SPERT - Special Power Excursion Reactor Tests Destructive Test number 1 On Aluminum, Highly Enriched Plate Type Core. A test studying the behavior of the reactor under destructive conditions on a light water moderated pool-type reactor with a plate-type core.

Specifying the core network supporting episodic simulation and episodic memory by activation likelihood estimation.

PubMed

Benoit, Roland G; Schacter, Daniel L

2015-08-01

It has been suggested that the simulation of hypothetical episodes and the recollection of past episodes are supported by fundamentally the same set of brain regions. The present article specifies this core network via Activation Likelihood Estimation (ALE). Specifically, a first meta-analysis revealed joint engagement of expected core-network regions during episodic memory and episodic simulation. These include parts of the medial surface, the hippocampus and parahippocampal cortex within the medial temporal lobes, and the temporal and inferior posterior parietal cortices on the lateral surface. Both capacities also jointly recruited additional regions such as parts of the bilateral dorsolateral prefrontal cortex. All of these core regions overlapped with the default network. Moreover, it has further been suggested that episodic simulation may require a stronger engagement of some of the core network's nodes as well as the recruitment of additional brain regions supporting control functions. A second ALE meta-analysis indeed identified such regions that were consistently more strongly engaged during episodic simulation than episodic memory. These comprised the core-network clusters located in the left dorsolateral prefrontal cortex and posterior inferior parietal lobe and other structures distributed broadly across the default and fronto-parietal control networks. Together, the analyses determine the set of brain regions that allow us to experience past and hypothetical episodes, thus providing an important foundation for studying the regions' specialized contributions and interactions. Copyright © 2015 Elsevier Ltd. All rights reserved.

Porous silicon omnidirectional mirrors and distributed Bragg reflectors for planar waveguide applications

NASA Astrophysics Data System (ADS)

Xifré-Pérez, E.; Marsal, L. F.; Ferré-Borrull, J.; Pallarès, J.

2007-09-01

The use of omnidirectional mirrors (an special case of distributed Bragg reflectors) as cladding for planar waveguides is proposed and analyzed. The proposed structure is an all-porous silicon multilayer consisting of a core layer inserted between two omnidirectional mirrors. The transfer matrix method is applied for the modal analysis. The influence of the parameters of the waveguide structure on the guided modes is analyzed. These parameters are the layer thickness and number of periods of the omnidirectional mirror, and the refractive index and thickness of the core layer. Finally, the confinement of the omnidirectional mirror cladding is analyzed with respect to two other different distributed Bragg reflector claddings.

Mapping and converting essential Federal Geographic Data Committee (FGDC) metadata into MARC21 and Dublin Core: towards an alternative to the FGDC Clearinghouse

USGS Publications Warehouse

Chandler, A.; Foley, D.; Hafez, A.M.

2000-01-01

The purpose of this article is to raise and address a number of issues related to the conversion of Federal Geographic Data Committee metadata into MARC21 and Dublin Core. We present an analysis of 466 FGDC metadata records housed in the National Biological Information Infrastructure (NBII) node of the FGDC Clearinghouse, with special emphasis on the length of fields and the total length of records in this set. One of our contributions is a 34 element crosswalk, a proposal that takes into consideration the constraints of the MARC21 standard as implemented in OCLC's World Cat and the realities of user behavior.

Genome-Wide Analysis of the Core DNA Replication Machinery in the Higher Plants Arabidopsis and Rice1[W][OA

PubMed Central

Shultz, Randall W.; Tatineni, Vinaya M.; Hanley-Bowdoin, Linda; Thompson, William F.

2007-01-01

Core DNA replication proteins mediate the initiation, elongation, and Okazaki fragment maturation functions of DNA replication. Although this process is generally conserved in eukaryotes, important differences in the molecular architecture of the DNA replication machine and the function of individual subunits have been reported in various model systems. We have combined genome-wide bioinformatic analyses of Arabidopsis (Arabidopsis thaliana) and rice (Oryza sativa) with published experimental data to provide a comprehensive view of the core DNA replication machinery in plants. Many components identified in this analysis have not been studied previously in plant systems, including the GINS (go ichi ni san) complex (PSF1, PSF2, PSF3, and SLD5), MCM8, MCM9, MCM10, NOC3, POLA2, POLA3, POLA4, POLD3, POLD4, and RNASEH2. Our results indicate that the core DNA replication machinery from plants is more similar to vertebrates than single-celled yeasts (Saccharomyces cerevisiae), suggesting that animal models may be more relevant to plant systems. However, we also uncovered some important differences between plants and vertebrate machinery. For example, we did not identify geminin or RNASEH1 genes in plants. Our analyses also indicate that plants may be unique among eukaryotes in that they have multiple copies of numerous core DNA replication genes. This finding raises the question of whether specialized functions have evolved in some cases. This analysis establishes that the core DNA replication machinery is highly conserved across plant species and displays many features in common with other eukaryotes and some characteristics that are unique to plants. PMID:17556508

Anterior knee pain

MedlinePlus

... squat to look at muscle imbalance and your core stability. X-rays are very often normal. However, ... and hamstring muscles. Learn exercises to strengthen your core. Lose weight (if you are overweight). Use special ...

Analysis of an Aircraft Honeycomb Sandwich Panel with Circular Face Sheet/Core Disbond Subjected to Ground-Air Pressurization

NASA Technical Reports Server (NTRS)

Rinker, Martin; Krueger, Ronald; Ratcliffe, James

2013-01-01

The ground-air pressurization of lightweight honeycomb sandwich structures caused by alternating pressure differences between the enclosed air within the honeycomb core and the ambient environment is a well-known and controllable loading condition of aerospace structures. However, initial face sheet/core disbonds intensify the face sheet peeling effect of the internal pressure load significantly and can decrease the reliability of the sandwich structure drastically. Within this paper, a numerical parameter study was carried out to investigate the criticality of initial disbonds in honeycomb sandwich structures under ground-air pressurization. A fracture mechanics approach was used to evaluate the loading at the disbond front. In this case, the strain energy release rate was computed via the Virtual Crack Closure Technique. Special attention was paid to the pressure-deformation coupling which can decrease the pressure load within the disbonded sandwich section significantly when the structure is highly deformed.

Paraprofessional Implementation of Evidence-Based Practices for Special Education Students

ERIC Educational Resources Information Center

Bubb-McKinnie, Esther

2017-01-01

Paraprofessionals often constitute the primary support system for special education students and are core members of special education instructional teams. Therefore, the Individuals With Disabilities Education Act requires that paraprofessionals receive adequate training, including training in evidence-based practices (EBP). However,…

Chromium doped nano-phase separated yttria-alumina-silica glass based optical fiber preform: fabrication and characterization

NASA Astrophysics Data System (ADS)

Dutta, Debjit; Dhar, Anirban; Das, Shyamal; Bysakh, Sandip; Kir'yanov, Alexandar; Paul, Mukul Chandra

2015-06-01

Transition metal (TM) doping in silica core optical fiber is one of the research area which has been studied for long time and Chromium (Cr) doping specially attracts a lot of research interest due to their broad emission band covering U, C and L band with many potential application such as saturable absorber or broadband amplifier etc. This paper present fabrication of Cr doped nano-phase separated silica fiber within yttria-alumina-silica core glass through conventional Modified Chemical Vapor Deposition (MCVD) process coupled with solution doping technique along with different material and optical characterization. For the first time scanning electron microscope (SEM) / energy dispersive X-ray (EDX) analysis of porous soot sample and final preform has been utilized to investigate incorporation mechanism of Crions with special emphasis on Cr-species evaporation at different stages of fabrication. We also report that optimized annealing condition of our fabricated preform exhibited enhanced fluorescence emission and a broad band within 550- 800 nm wavelength region under pumping at 532 nm wavelength due to nano-phase restructuration.

Fukushima Daiichi Unit 1 ex-vessel prediction: Core melt spreading

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farmer, M. T.; Robb, K. R.; Francis, M. W.

Lower head failure and corium-concrete interaction were predicted to occur at Fukushima Daiichi Unit 1 (1F1) by several different system-level code analyses, including MELCOR v2.1 and MAAP5. Although these codes capture a wide range of accident phenomena, they do not contain detailed models for ex-vessel core melt behavior. However, specialized codes exist for analysis of ex-vessel melt spreading (e.g., MELTSPREAD) and long-term debris coolability (e.g., CORQUENCH). On this basis, an analysis has been carried out to further evaluate ex-vessel behavior for 1F1 using MELTSPREAD and CORQUENCH. Best-estimate melt pour conditions predicted by MELCOR v2.1 and MAAP5 were used as input.more » MELTSPREAD was then used to predict the spatially-dependent melt conditions and extent of spreading during relocation from the vessel. Lastly, this information was then used as input for the long-term debris coolability analysis with CORQUENCH that is reported in a companion paper.« less

Fukushima Daiichi Unit 1 ex-vessel prediction: Core melt spreading

DOE PAGES

Farmer, M. T.; Robb, K. R.; Francis, M. W.

2016-10-31

Lower head failure and corium-concrete interaction were predicted to occur at Fukushima Daiichi Unit 1 (1F1) by several different system-level code analyses, including MELCOR v2.1 and MAAP5. Although these codes capture a wide range of accident phenomena, they do not contain detailed models for ex-vessel core melt behavior. However, specialized codes exist for analysis of ex-vessel melt spreading (e.g., MELTSPREAD) and long-term debris coolability (e.g., CORQUENCH). On this basis, an analysis has been carried out to further evaluate ex-vessel behavior for 1F1 using MELTSPREAD and CORQUENCH. Best-estimate melt pour conditions predicted by MELCOR v2.1 and MAAP5 were used as input.more » MELTSPREAD was then used to predict the spatially-dependent melt conditions and extent of spreading during relocation from the vessel. Lastly, this information was then used as input for the long-term debris coolability analysis with CORQUENCH that is reported in a companion paper.« less

34 CFR 300.18 - Highly qualified special education teachers.

Code of Federal Regulations, 2014 CFR

2014-07-01

... subjects. For any public elementary or secondary school special education teacher teaching core academic... school or secondary school special education teacher teaching in a State, highly qualified requires that..., except that when used with respect to any teacher teaching in a public charter school, highly qualified...

34 CFR 300.18 - Highly qualified special education teachers.

Code of Federal Regulations, 2013 CFR

2013-07-01

... subjects. For any public elementary or secondary school special education teacher teaching core academic... school or secondary school special education teacher teaching in a State, highly qualified requires that..., except that when used with respect to any teacher teaching in a public charter school, highly qualified...

34 CFR 300.18 - Highly qualified special education teachers.

Code of Federal Regulations, 2012 CFR

2012-07-01

... subjects. For any public elementary or secondary school special education teacher teaching core academic... school or secondary school special education teacher teaching in a State, highly qualified requires that..., except that when used with respect to any teacher teaching in a public charter school, highly qualified...

34 CFR 300.18 - Highly qualified special education teachers.

Code of Federal Regulations, 2011 CFR

2011-07-01

... subjects. For any public elementary or secondary school special education teacher teaching core academic... school or secondary school special education teacher teaching in a State, highly qualified requires that..., except that when used with respect to any teacher teaching in a public charter school, highly qualified...

Special Advanced Course for Core Sciences to Bring Up Project Leaders

NASA Astrophysics Data System (ADS)

Inagaki, Kenji; Tabata, Nobuhisa; Gofuku, Akio; Harada, Isao; Takada, Jun

Special Advanced Course for Core Sciences has been introduced recently to Graduate School of Natural Science and Technology, Okayama University, to bring up a project leader. The following points are key education goals in this program : (1) knowledge of core sciences, (2) communication ability by using English, and (3) wide viewpoints for researches. In order to accomplish these goals, several lectures for core sciences, patent systems and engineering ethics as well as long term internships by the collaboration with some regional companies have been put in practice. In this paper, we describe the outline of the program, educational effects, and our experiences. Then, we discuss how effective the program is for bringing up an engineer or a scientist who can lead sciences and technologies of their domains. This paper also describes current activities of the program.

40 CFR 467.61 - Specialized definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

....61 Specialized definitions. For the purpose of this subpart: (a) The “core” of the drawing with... any operation not previously included in the core, performed on-site, following or preceding the...

40 CFR 467.21 - Specialized definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Specialized definitions. For the purpose of this subpart: (a) The “core” of the rolling with emulsions... included in the core, performed on-site, following or preceding the rolling operation. The ancillary...

A Novel In-Beam Delayed Neutron Counting Technique for Characterization of Special Nuclear Materials

NASA Astrophysics Data System (ADS)

Bentoumi, G.; Rogge, R. B.; Andrews, M. T.; Corcoran, E. C.; Dimayuga, I.; Kelly, D. G.; Li, L.; Sur, B.

2016-12-01

A delayed neutron counting (DNC) system, where the sample to be analyzed remains stationary in a thermal neutron beam outside of the reactor, has been developed at the National Research Universal (NRU) reactor of the Canadian Nuclear Laboratories (CNL) at Chalk River. The new in-beam DNC is a novel approach for non-destructive characterization of special nuclear materials (SNM) that could enable identification and quantification of fissile isotopes within a large and shielded sample. Despite the orders of magnitude reduction in neutron flux, the in-beam DNC method can be as informative as the conventional in-core DNC for most cases while offering practical advantages and mitigated risk when dealing with large radioactive samples of unknown origin. This paper addresses (1) the qualification of in-beam DNC using a monochromatic thermal neutron beam in conjunction with a proven counting apparatus designed originally for in-core DNC, and (2) application of in-beam DNC to an examination of large sealed capsules containing unknown radioactive materials. Initial results showed that the in-beam DNC setup permits non-destructive analysis of bulky and gamma shielded samples. The method does not lend itself to trace analysis, and at best could only reveal the presence of a few milligrams of 235U via the assay of in-beam DNC total counts. Through analysis of DNC count rates, the technique could be used in combination with other neutron or gamma techniques to quantify isotopes present within samples.

Related Core Academic Knowledge and Skills. Georgia Core Standards for Occupational Clusters.

ERIC Educational Resources Information Center

Georgia Univ., Athens. Dept. of Occupational Studies.

This document lists the industry-identified core academic knowledge and skills that should be possessed by all Georgia students who are enrolled in occupational cluster programs and are preparing to enter the work force or continue their occupational specialization at the postsecondary level. First, 63 related communications competencies are…

Study on micro-bend light transmission performance of novel liquid-core optical fiber

NASA Astrophysics Data System (ADS)

Ma, Junyan; Zhao, Zhimin; Wang, Kaisheng; Guo, Linfeng

2007-01-01

With the increasing development of material technology and electronic integration technology, optical fiber and its using in smart structure have become hot in the field of material research. And liquid-core optical fiber is a special kind of optical fiber, which is made using liquid material as core and polymer material as optical layer and protective covering, and it has the characteristics of large core diameter, high numerical aperture, large-scope and efficient spectrum transmission and long life for using. So the liquid-core optical fiber is very suitable for spectrum cure, ultraviolet solidification, fluorescence detection, criminal investigation and evidence obtainment, etc, and especially as light transfer element in some new structures for the measurement of some signals, such as concentration, voltage, temperature, light intensity and so on. In this paper, the novel liquid-core optical fiber is self-made, and then through the test of its light transmission performance in free state, the relation between axial micro-bend and light-intensity loss are presented. When the liquid-core optical fiber is micro-bent axially, along with the axial displacement's increase, output power of light is reducing increasingly, and approximately has linear relation to micro-displacement in a range. According to the results liquid-core fiber-optic micro-bend sensor can be designed to measure micro-displacement of the tested objects. Experimental data and analysis provide experimental basis for further application of liquid-core optical fiber.

40 CFR 467.11 - Specialized definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Specialized definitions. For the purpose of this subpart: (a) The “core” of the rolling with neat oils... operation not previously included in the core, performed on-site, following or preceding the rolling...

40 CFR 467.51 - Specialized definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Specialized definitions. For the purpose of this subpart: (a) The “core” of the drawing with neat oils... in the core, performed on-site, following or preceding the drawing operation. The ancillary operation...

40 CFR 467.11 - Specialized definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Specialized definitions. For the purpose of this subpart: (a) The “core” of the rolling with neat oils... operation not previously included in the core, performed on-site, following or preceding the rolling...

40 CFR 467.51 - Specialized definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Specialized definitions. For the purpose of this subpart: (a) The “core” of the drawing with neat oils... in the core, performed on-site, following or preceding the drawing operation. The ancillary operation...

Using Lesson Study to Prepare Preservice Special Educators

ERIC Educational Resources Information Center

Roberts, Carly A.; Benedict, Amber E.; Kim, So Yeon; Tandy, Jacob

2018-01-01

Learning to teach students with disabilities is challenging. Preservice special educators must develop critical knowledge of content as well as skill for enacting evidence-based practices effectively. Preservice special educators need increased opportunities to learn core knowledge coupled with a mechanism to support them in situating their newly…

A comparative analysis of moral principles and behavioral norms in eight ethical codes relevant to health sciences librarianship, medical informatics, and the health professions.

PubMed

Byrd, Gary D; Winkelstein, Peter

2014-10-01

Based on the authors' shared interest in the interprofessional challenges surrounding health information management, this study explores the degree to which librarians, informatics professionals, and core health professionals in medicine, nursing, and public health share common ethical behavior norms grounded in moral principles. Using the "Principlism" framework from a widely cited textbook of biomedical ethics, the authors analyze the statements in the ethical codes for associations of librarians (Medical Library Association [MLA], American Library Association, and Special Libraries Association), informatics professionals (American Medical Informatics Association [AMIA] and American Health Information Management Association), and core health professionals (American Medical Association, American Nurses Association, and American Public Health Association). This analysis focuses on whether and how the statements in these eight codes specify core moral norms (Autonomy, Beneficence, Non-Maleficence, and Justice), core behavioral norms (Veracity, Privacy, Confidentiality, and Fidelity), and other norms that are empirically derived from the code statements. These eight ethical codes share a large number of common behavioral norms based most frequently on the principle of Beneficence, then on Autonomy and Justice, but rarely on Non-Maleficence. The MLA and AMIA codes share the largest number of common behavioral norms, and these two associations also share many norms with the other six associations. The shared core of behavioral norms among these professions, all grounded in core moral principles, point to many opportunities for building effective interprofessional communication and collaboration regarding the development, management, and use of health information resources and technologies.

A comparative analysis of moral principles and behavioral norms in eight ethical codes relevant to health sciences librarianship, medical informatics, and the health professions

PubMed Central

Byrd, Gary D.; Winkelstein, Peter

2014-01-01

Objective: Based on the authors' shared interest in the interprofessional challenges surrounding health information management, this study explores the degree to which librarians, informatics professionals, and core health professionals in medicine, nursing, and public health share common ethical behavior norms grounded in moral principles. Methods: Using the “Principlism” framework from a widely cited textbook of biomedical ethics, the authors analyze the statements in the ethical codes for associations of librarians (Medical Library Association [MLA], American Library Association, and Special Libraries Association), informatics professionals (American Medical Informatics Association [AMIA] and American Health Information Management Association), and core health professionals (American Medical Association, American Nurses Association, and American Public Health Association). This analysis focuses on whether and how the statements in these eight codes specify core moral norms (Autonomy, Beneficence, Non-Maleficence, and Justice), core behavioral norms (Veracity, Privacy, Confidentiality, and Fidelity), and other norms that are empirically derived from the code statements. Results: These eight ethical codes share a large number of common behavioral norms based most frequently on the principle of Beneficence, then on Autonomy and Justice, but rarely on Non-Maleficence. The MLA and AMIA codes share the largest number of common behavioral norms, and these two associations also share many norms with the other six associations. Implications: The shared core of behavioral norms among these professions, all grounded in core moral principles, point to many opportunities for building effective interprofessional communication and collaboration regarding the development, management, and use of health information resources and technologies. PMID:25349543

Quantum chemical calculation of the equilibrium structures of small metal atom clusters

NASA Technical Reports Server (NTRS)

Kahn, L. R.

1982-01-01

Metal atom clusters are studied based on the application of ab initio quantum mechanical approaches. Because these large 'molecular' systems pose special practical computational problems in the application of the quantum mechanical methods, there is a special need to find simplifying techniques that do not compromise the reliability of the calculations. Research is therefore directed towards various aspects of the implementation of the effective core potential technique for the removal of the metal atom core electrons from the calculations.

PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways): Introduction and overview

NASA Astrophysics Data System (ADS)

Ó Cofaigh, Colm; Briner, Jason P.; Kirchner, Nina; Lucchi, Renata G.; Meyer, Hanno; Kaufman, Darrell S.

2016-09-01

This special issue relates to the Second International Conference of the PAST Gateways (Palaeo-Arctic Spatial and Temporal Gateways) network which was held in Trieste, Italy in 2014. Twenty five papers are included and they address topics under four main themes: (1) The growth and decay of Arctic ice sheets; (2) Arctic sea ice and palaeoceanography; (3) Terrestrial Arctic environments and permafrost change; and (4) Holocene Arctic environmental change. Geographically the focus is circum-Arctic; the special issue includes detailed regional studies from Greenland, Scandinavia, Russia, and Arctic North America and the adjoining seas, as well as a series of synthesis-type, review papers on Fennoscandian Ice Sheet deglaciation and Holocene Arctic palaeo-climate change. The methodologies employed are diverse and include marine sediment core and geophysical investigations, terrestrial glacial geology and geomorphology, isotopic analysis of ground ice, palaeo-ecological analysis of lacustrine and terrestrial sedimentary archives, geochronology and numerical ice sheet modeling.

Review of Recent US Value Frameworks-A Health Economics Approach: An ISPOR Special Task Force Report [6].

PubMed

Willke, Richard J; Neumann, Peter J; Garrison, Louis P; Ramsey, Scott D

2018-02-01

The sixth section of our Special Task Force (STF) report reviews and comments on recent US-oriented value assessment frameworks, specifically those published by the American College of Cardiology/American Heart Association, the Institute for Clinical and Economic Research, the American Society of Clinical Oncology, the National Comprehensive Cancer Network, and the Memorial Sloan Kettering Cancer Center. We review published commentaries that address the validity, reliability, and conceptual underpinnings of these frameworks. We find common themes of critique regarding the strengths and limitations across frameworks. Particular shortcomings of some frameworks pose greater threats to their face validity and utility compared with others. The most significant limitations include lack of clear perspective (e.g., patient vs. health plan) and poor transparency in accounting for costs and benefits. We then review how each framework adheres to core STF recommendations, with particular emphasis on whether the framework can be used to support coverage decisions by health insurers, and whether it adheres to core principles of cost-effectiveness analysis. The Institute for Clinical and Economic Research framework most closely adheres to core STF recommendations. Others have significant limitations that vary widely from framework to framework. We also review how the frameworks follow STF recommendations for addressing potentially relevant issues beyond cost-effectiveness analysis - for example, equity in resource allocation and patient heterogeneity. Finally, we review whether and how each framework uses value thresholds and addresses affordability concerns. We conclude with suggestions for further research, particularly in the areas of testing the measurement and use of novel elements of value and deliberative processes. Copyright © 2018 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

46 CFR 35.01-25 - Sacrificial anode installations-TB/ALL.

Code of Federal Regulations, 2012 CFR

2012-10-01

... bolted connections to the supporting structure. Special consideration will be given to proprietary... utilize a mild steel core with necessary attachments. Other types may be used but will require special...

The development of specialized palliative care in the community: A qualitative study of the evolution of 15 teams.

PubMed

Seow, Hsien; Bainbridge, Daryl

2018-05-01

Interprofessional specialized palliative care teams at home improve patient outcomes, reduce healthcare costs, and support many patients to die at home. However, practical details about how to develop home-based teams in different regions and health systems are scarce. To examine how a variety of home-based specialized palliative care teams created and grew their team over time and to identify critical steps in their evolution. A qualitative study was designed based on a grounded theory approach, using semi-structured interviews and other documentation. In all, 15 specialized palliative care teams from Ontario, Canada, representing rural and urban areas. Data were collected from core members of the teams, including nurses, physicians, personal support workers, spiritual counselors, and administrators. In all, 122 individuals where interviewed, ranging from 4 to 10 per team. The analysis revealed four stages in team evolution: Inception, Start-up (n = 4 teams), Growth (n = 5), and Mature (n = 6). In the Inception stage, a champion provider was required to leverage existing resources to form the team. Start-up teams were testing and adjusting care processes to solidify their presence in the community. Growth teams had core expertise, relationships with fellow providers, and 24/7 support. Mature teams were fully integrated in the community, but still engaged in continuous quality improvement. Understanding the developmental stages of teams can help to inform the progress of other community-based teams. Appropriate outcome measures at each stage are also critical for team motivation and steady progress.

An analysis of the medical specialty training system in Spain.

PubMed

Freire, José-Manuel; Infante, Alberto; de Aguiar, Adriana Cavalcanti; Carbajo, Pilar

2015-06-02

In this paper, we analyse the medical specialty training system in Spain (the so-called "residency system"). In order to do so, we a) summarize its historical evolution; b) describe the five major architectural pillars on which the system is currently based; c) analyse the special contract of the specialist-in-training; d) discuss the three major challenges for the medical specialist training future: the evolution and expansion of the residency system to other health professions, the issue of grouping specialties with a common core trunk and the continuity of the learning process; and e) draw four conclusions that may be relevant for those who are in the process of developing or revising their own medical specialization systems.

Cyclical Changes in the Pleistocene Climate from an Analysis of Biogenic Silica in a Bottom Sediment Core Sample of Lake Baikal

NASA Astrophysics Data System (ADS)

Dergachev, V. A.; Dmitriev, P. B.

2017-12-01

An inhomogeneous time series of measurements of the percentage content of biogenic silica in the samples of joint cores BDP-96-1 and BDP-96-2 from the bottom of Lake Baikal drilled at a depth of 321 m under water has been analyzed. The composite depth of cores is 77 m, which covers the Pleistocene Epoch to 1.8 Ma. The time series was reduced to a regular form with a time step of 1 kyr, which allowed 16 distinct quasi-periodic components with periods from 19 to 251 kyr to be revealed in this series at a significance level of their amplitudes exceeding 4σ. For this, the combined spectral periodogram (a modification of the spectral analysis method) was used. Some of the revealed quasi-harmonics are related to the characteristic cyclical oscillations of the Earth's orbital parameters. Special focus was payed to the temporal change in the parameters of the revealed quasi-harmonic components over the Pleistocene Epoch, which was studied by constructing the spectral density of the analyzed data in the running window of 201 and 701 kyr.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paulauskas, Tadas; Buurma, Christopher; Colegrove, Eric

Dislocation cores have long dominated the electronic and optical behaviors of semiconductor devices and detailed atomic characterization is required to further explore their effects. Miniaturization of semiconductor devices to nanometre scale also puts emphasis on a material's mechanical properties to withstand failure due to processing or operational stresses. Sessile junctions of dislocations provide barriers to propagation of mobile dislocations and may lead to work-hardening. The sessile Lomer–Cottrell and Hirth lock dislocations, two stable lowest elastic energy stair-rods, are studied in this paper. More specifically, using atomic resolution high-angle annular dark-field imaging and atomic-column-resolved X-ray spectrum imaging in an aberration-corrected scanningmore » transmission electron microscope, dislocation core structures are examined in zinc-blende CdTe. A procedure is outlined for atomic scale analysis of dislocation junctions which allows determination of their identity with specially tailored Burgers circuits and also formation mechanisms of the polar core structures based on Thompson's tetrahedron adapted to reactions of polar dislocations as they appear in CdTe and other zinc-blende solids. Strain fields associated with the dislocations calculatedviageometric phase analysis are found to be diffuse and free of `hot spots' that reflect compact structures and low elastic energy of the pure-edge stair-rods.« less

Monitoring of NMR porosity changes in the full-size core salvage through the drying process

NASA Astrophysics Data System (ADS)

Fattakhov, Artur; Kosarev, Victor; Doroginitskii, Mikhail; Skirda, Vladimir

2015-04-01

Currently the principle of nuclear magnetic resonance (NMR) is one of the most popular technologies in the field of borehole geophysics and core analysis. Results of NMR studies allow to calculate the values of the porosity and permeability of sedimentary rocks with sufficient reliability. All standard tools for the study of core salvage on the basis of NMR have significant limitations: there is considered only long relaxation times corresponding to the mobile formation fluid. Current trends in energy obligate to move away from conventional oil to various alternative sources of energy. One of these sources are deposits of bitumen and high-viscosity oil. In Kazan (Volga Region) Federal University (Russia) there was developed a mobile unit for the study of the full-length core salvage by the NMR method ("NMR-Core") together with specialists of "TNG-Group" (a company providing maintenance services to oil companies). This unit is designed for the study of core material directly on the well, after removing it from the core receiver. The maximum diameter of the core sample may be up to 116 mm, its length (or length of the set of samples) may be up to 1000 mm. Positional precision of the core sample relative to the measurement system is 1 mm, and the spatial resolution along the axis of the core is 10 mm. Acquisition time of the 1 m core salvage varies depending on the mode of research and is at least 20 minutes. Furthermore, there is implemented a special investigation mode of the core samples with super small relaxation times (for example, heavy oil) is in the tool. The aim of this work is tracking of the NMR porosity changes in the full-size core salvage in time. There was used a water-saturated core salvage from the shallow educational well as a sample. The diameter of the studied core samples is 93 mm. There was selected several sections length of 1m from the 200-meter coring interval. The studied core samples are being measured several times. The time interval between the measurements is from 1 hour to 48 hours. Making the measurements it possible to draw conclusions about that the processes of NMR porosity changes in time as a result of evaporation of the part of fluid from the surface layer of the core salvage and suggest a core analysis technique directly on the well. This work is supported by the grant of Ministry of Education and Science of the Russian Federation (project No. 02.G25.31.0029).

Attaining Success for Beginning Special Education Teachers.

ERIC Educational Resources Information Center

McCabe, Marjorie; And Others

1993-01-01

Three case studies are presented that highlight problem scenarios relating to beginning special education intern teachers and explain how the teachers attained success. The cases focus on classroom management, adaptation of the core curriculum, and knowledge of instructional practices. (JDD)

Petrology and geochemistry of lithic fragments separated from the Apollo 15 deep-drill core

NASA Technical Reports Server (NTRS)

Lindstrom, M. M.; Nielsen, R. L.; Drake, M. J.

1977-01-01

Petrological and geochemical analysis of lithic fragments separated from the Apollo 15 deep-drill core showed these fragments to fall into the essentially the same range of rock types as observed in surface soil samples and large rock samples. Three particles are singled out as being of special interest. One sample is a mare basalt containing extremely evolved phases. The particle may represent small-scale imperfect crystal/liquid separation in a lava flow. A green glass particle is not the ultramafic emerald green glass described from the Apollo 15 site, but rather an ANT-like light green color, and has a quite different chemical composition from the ultramafic variety. One mare basalt displays a positive Eu anomaly and is enriched in plagioclase relative to olivine plus pyroxene.

Analysis of C/E results of fission rate ratio measurements in several fast lead VENUS-F cores

NASA Astrophysics Data System (ADS)

Kochetkov, Anatoly; Krása, Antonín; Baeten, Peter; Vittiglio, Guido; Wagemans, Jan; Bécares, Vicente; Bianchini, Giancarlo; Fabrizio, Valentina; Carta, Mario; Firpo, Gabriele; Fridman, Emil; Sarotto, Massimo

2017-09-01

During the GUINEVERE FP6 European project (2006-2011), the zero-power VENUS water-moderated reactor was modified into VENUS-F, a mock-up of a lead cooled fast spectrum system with solid components that can be operated in both critical and subcritical mode. The Fast Reactor Experiments for hybrid Applications (FREYA) FP7 project was launched in 2011 to support the designs of the MYRRHA Accelerator Driven System (ADS) and the ALFRED Lead Fast Reactor (LFR). Three VENUS-F critical core configurations, simulating the complex MYRRHA core design and one configuration devoted to the LFR ALFRED core conditions were investigated in 2015. The MYRRHA related cores simulated step by step design peculiarities like the BeO reflector and in pile sections. For all of these cores the fuel assemblies were of a simple design consisting of 30% enriched metallic uranium, lead rodlets to simulate the coolant and Al2O3 rodlets to simulate the oxide fuel. Fission rate ratios of minor actinides such as Np-237, Am-241 as well as Pu-239, Pu-240, Pu-242 and U-238 to U-235 were measured in these VENUS-F critical assemblies with small fission chambers in specially designed locations, to determine the spectral indices in the different neutron spectrum conditions. The measurements have been analyzed using advanced computational tools including deterministic and stochastic codes and different nuclear data sets like JEFF-3.1, JEFF-3.2, ENDF/B7.1 and JENDL-4.0. The analysis of the C/E discrepancies will help to improve the nuclear data in the specific energy region of fast neutron reactor spectra.

[Habitat factor analysis for Torreya grandis cv. Merrillii based on spatial information technology].

PubMed

Wang, Xiao-ming; Wang, Ke; Ao, Wei-jiu; Deng, Jin-song; Han, Ning; Zhu, Xiao-yun

2008-11-01

Torreya grandis cv. Merrillii, a tertiary survival plant, is a rare tree species of significant economic value and expands rapidly in China. Its special habitat factor analysis has the potential value to provide guide information for its planting, management, and sustainable development, because the suitable growth conditions for this tree species are special and strict. In this paper, the special habitat factors for T. grandis cv. Merrillii in its core region, i.e., in seven villages of Zhuji City, Zhejiang Province were analyzed with Principal Component Analysis (PCA) and a series of data, such as IKONOS image, Digital Elevation Model (DEM), and field survey data supported by the spatial information technology. The results showed that T. grandis cv. Merrillii exhibited high selectivity of environmental factors such as elevation, slope, and aspect. 96.22% of T. grandis cv. Merrillii trees were located at the elevation from 300 to 600 m, 97.52% of them were found to present on the areas whose slope was less than 300, and 74.43% of them distributed on sunny and half-sunny slopes. The results of PCA analysis indicated that the main environmental factors affecting the habitat of T. grandis cv. Merrillii were moisture, heat, and soil nutrients, and moisture might be one of the most important ecological factors for T. grandis cv. Merrillii due to the unique biological and ecological characteristics of the tree species.

The SAS4A/SASSYS-1 Safety Analysis Code System, Version 5

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fanning, T. H.; Brunett, A. J.; Sumner, T.

The SAS4A/SASSYS-1 computer code is developed by Argonne National Laboratory for thermal, hydraulic, and neutronic analysis of power and flow transients in liquidmetal- cooled nuclear reactors (LMRs). SAS4A was developed to analyze severe core disruption accidents with coolant boiling and fuel melting and relocation, initiated by a very low probability coincidence of an accident precursor and failure of one or more safety systems. SASSYS-1, originally developed to address loss-of-decay-heat-removal accidents, has evolved into a tool for margin assessment in design basis accident (DBA) analysis and for consequence assessment in beyond-design-basis accident (BDBA) analysis. SAS4A contains detailed, mechanistic models of transientmore » thermal, hydraulic, neutronic, and mechanical phenomena to describe the response of the reactor core, its coolant, fuel elements, and structural members to accident conditions. The core channel models in SAS4A provide the capability to analyze the initial phase of core disruptive accidents, through coolant heat-up and boiling, fuel element failure, and fuel melting and relocation. Originally developed to analyze oxide fuel clad with stainless steel, the models in SAS4A have been extended and specialized to metallic fuel with advanced alloy cladding. SASSYS-1 provides the capability to perform a detailed thermal/hydraulic simulation of the primary and secondary sodium coolant circuits and the balance-ofplant steam/water circuit. These sodium and steam circuit models include component models for heat exchangers, pumps, valves, turbines, and condensers, and thermal/hydraulic models of pipes and plena. SASSYS-1 also contains a plant protection and control system modeling capability, which provides digital representations of reactor, pump, and valve controllers and their response to input signal changes.« less

Measuring Helicase Inhibition of the DEAD-box Protein Dbp2 by Yra1

PubMed Central

Ma, Wai Kit; Tran, Elizabeth J.

2016-01-01

Despite the highly conserved helicase core, individual DEAD-box proteins are specialized in diverse RNA metabolic processes. One mechanism that determines DEAD-box protein specificity is enzymatic regulation by other protein cofactors. In this chapter, we describe a protocol for purifying the Saccharomyces cerevisiae DEAD-box RNA helicase Dbp2 and RNA-binding protein Yra1 and subsequent analysis of helicase regulation. The experiments described here can be adapted to RNA helicase and purified co-factor. PMID:25579587

Discussion on Microwave-Matter Interaction Mechanisms by In Situ Observation of "Core-Shell" Microstructure during Microwave Sintering.

PubMed

Liu, Wenchao; Xu, Feng; Li, Yongcun; Hu, Xiaofang; Dong, Bo; Xiao, Yu

2016-02-23

This research aims to deepen the understanding of the interaction mechanisms between microwave and matter in a metal-ceramic system based on in situ synchrotron radiation computed tomography. A special internal "core-shell" microstructure was discovered for the first time and used as an indicator for the interaction mechanisms between microwave and matter. Firstly, it was proved that the microwave magnetic field acted on metal particles by way of inducing an eddy current in the surface of the metal particles, which led to the formation of a "core-shell" microstructure in the metal particles. On this basis, it was proposed that the ceramic particles could change the microwave field and open a way for the microwave, thereby leading to selective heating in the region around the ceramic particles, which was verified by the fact that all the "core-shell" microstructure was located around ceramic particles. Furthermore, it was indicated that the ceramic particles would gather the microwaves, and might lead to local heating in the metal-ceramic contact region. The focusing of the microwave was proved by the quantitative analysis of the evolution rate of the "core-shell" microstructure in a different region. This study will help to reveal the microwave-matter interaction mechanisms during microwave sintering.

In vitro evaluation of five core materials.

PubMed

Gu, Steven; Rasimick, Brian J; Deutsch, Allan S; Musikant, Barry L

2007-01-01

This in vitro study determined the fracture strength of five core materials supported by two different endodontic dowels. Diametral tensile strength and microhardness of the three resin composite core materials used in this study were also tested. The fracture strength study used one lanthanide-reinforced flowable resin composite (Ti-Core Auto E), one titanium- and lanthanide-reinforced composite (Ti-Core), one lanthanide-reinforced composite (Ti-Core Natural), and two metal-reinforced glass ionomer core materials (Ketac Silver and GC Miracle Mix). Two types of dowels were used: a multitiered, split-shank threaded dowel with a flange (#1 Flexi-Flange) and one without a flange design (#1 Flexi-Post). The specimens were divided into ten groups. Each tooth/dowel and core specimen was placed in a special jig at 45 degrees and subjected to a load by a universal testing machine. The diametral tensile strength and the microhardness of the three resin composite core materials were measured by a universal testing machine and Barcol hardness tester, respectively. All test groups contained ten specimens. The fracture strength value of the resin composite core materials was significantly larger ( p < 0.0001) than those for the metal-reinforced glass-ionomer core materials. Analysis of variance (ANOVA) also showed that the Flexi-Flange dowel interacted with Ti-Core and Ti-Core Auto E to significantly ( p < 0.0013) increase the fracture strength relative to the Flexi-Post. One-way ANOVA revealed that there were no significant differences between them in terms of diametral tensile strength. The Barcol hardness values of the composite core materials were statistically different ( p < 0.0001), with the Ti-Core the highest, followed by Ti-Core Natural, then Ti-Core Auto E. Resin composite core material performed better than glass ionomer material in this in vitro study. The flowable composite core material performed about the same in terms of fracture strength and diametral tensile strength compared with nonflowable composites. Combined with certain core materials, the flange design increased the fracture strength of the tooth/dowel and core combination.

A Preliminary Core Domain Set for Clinical Trials of Shoulder Disorders: A Report from the OMERACT 2016 Shoulder Core Outcome Set Special Interest Group.

PubMed

Buchbinder, Rachelle; Page, Matthew J; Huang, Hsiaomin; Verhagen, Arianne P; Beaton, Dorcas; Kopkow, Christian; Lenza, Mario; Jain, Nitin B; Richards, Bethan; Richards, Pamela; Voshaar, Marieke; van der Windt, Danielle; Gagnier, Joel J

2017-12-01

The Outcome Measures in Rheumatology (OMERACT) Shoulder Core Outcome Set Special Interest Group (SIG) was established to develop a core outcome set (COS) for clinical trials of shoulder disorders. In preparation for OMERACT 2016, we systematically examined all outcome domains and measurement instruments reported in 409 randomized trials of interventions for shoulder disorders published between 1954 and 2015. Informed by these data, we conducted an international Delphi consensus study including shoulder trial experts, clinicians, and patients to identify key domains that should be included in a shoulder disorder COS. Findings were discussed at a stakeholder premeeting of OMERACT. At OMERACT 2016, we sought consensus on a preliminary core domain set and input into next steps. There were 13 and 15 participants at the premeeting and the OMERACT 2016 SIG meeting, respectively (9 attended both meetings). Consensus was reached on a preliminary core domain set consisting of an inner core of 4 domains: pain, physical function/activity, global perceived effect, and adverse events including death. A middle core consisted of 3 domains: emotional well-being, sleep, and participation (recreation and work). An outer core of research required to inform the final COS was also formulated. Our next steps are to (1) analyze whether participation (recreation and work) should be in the inner core, (2) conduct a third Delphi round to finalize definitions and wording of domains and reach final endorsement for the domains, and (3) determine which instruments fulfill the OMERACT criteria for measuring each domain.

Evaluation of Features of Development of Sports Way of Swimming of Students of Various Sports Specialization

ERIC Educational Resources Information Center

Yermahanova, Amina; Nurmakhambetova, Dinara; Bozhig, Zhanbolat; Imanbetov, Amanbek

2016-01-01

Bachelor educational program "Physical culture and sport" must master special, substantive and core competencies, not only in the chosen specialization, but also in the basic sports, including "Swimming." It is a necessity due to the fact that the graduate program in order to protect their health and life should own at least…

Estimating the Effects of Teacher Certification on the Academic Achievement of Exceptional High School Students in North Carolina

ERIC Educational Resources Information Center

Montrosse, Bianca Elizabeth

2009-01-01

Legislative amendments contained in the most recent reauthorization of IDEA and NCLB have mandated that all students, including those with special needs, be taught by an appropriately certified teacher. Specifically, both of these laws require that teachers of special education students in core academic classes must meet state special education…

Determination of the /sup 237/Np(n, 2n) reaction cross section in the core of the BN-350 reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goncharov, R.K.; Zvonarev, A.V.; Ivanov, V.I.

1987-05-01

Analysis of irradiated fuel (regular fuel elements and special ampule samples) makes it possible to obtain data on the neutron-physical characteristics that do not lend themselves to measurement in experiments with a low neutron flux. The authors studied samples of spent fuel from regular fuel elements and samples of /sup 236/U and /sup 237/Np irradiated in special ampules. We give the results of measurements of the ratio (sigma/sub n,2n/ + sigma/sub ..gamma..,n/)sigma/sub c/ for /sup 237/Np in different zones of the BN-350 reactor and the results of calculations performed using the neptunium group constants calculated from the data of themore » files ENDFB IV and ENDFB V« less

Web buckling behavior under in-plane compression and shear loads for web reinforced composite sandwich core

NASA Astrophysics Data System (ADS)

Toubia, Elias Anis

Sandwich construction is one of the most functional forms of composite structures developed by the composite industry. Due to the increasing demand of web-reinforced core for composite sandwich construction, a research study is needed to investigate the web plate instability under shear, compression, and combined loading. If the web, which is an integral part of the three dimensional web core sandwich structure, happens to be slender with respect to one or two of its spatial dimensions, then buckling phenomena become an issue in that it must be quantified as part of a comprehensive strength model for a fiber reinforced core. In order to understand the thresholds of thickness, web weight, foam type, and whether buckling will occur before material yielding, a thorough investigation needs to be conducted, and buckling design equations need to be developed. Often in conducting a parametric study, a special purpose analysis is preferred over a general purpose analysis code, such as a finite element code, due to the cost and effort usually involved in generating a large number of results. A suitable methodology based on an energy method is presented to solve the stability of symmetrical and specially orthotropic laminated plates on an elastic foundation. Design buckling equations were developed for the web modeled as a laminated plate resting on elastic foundations. The proposed equations allow for parametric studies without limitation regarding foam stiffness, geometric dimensions, or mechanical properties. General behavioral trends of orthotropic and symmetrical anisotropic plates show pronounced contribution of the elastic foundation and fiber orientations on the buckling resistance of the plate. The effects of flexural anisotropy on the buckling behavior of long rectangular plates when subjected to pure shear loading are well represented in the model. The reliability of the buckling equations as a design tool is confirmed by comparison with experimental results. Comparing to predicted values, the experimental plate shear test results range between 15 and 35 percent, depending on the boundary conditions considered. The compression testing yielded conservative results, and as such, can provide a valuable tool for the designer.

CoreFlow: a computational platform for integration, analysis and modeling of complex biological data.

PubMed

Pasculescu, Adrian; Schoof, Erwin M; Creixell, Pau; Zheng, Yong; Olhovsky, Marina; Tian, Ruijun; So, Jonathan; Vanderlaan, Rachel D; Pawson, Tony; Linding, Rune; Colwill, Karen

2014-04-04

A major challenge in mass spectrometry and other large-scale applications is how to handle, integrate, and model the data that is produced. Given the speed at which technology advances and the need to keep pace with biological experiments, we designed a computational platform, CoreFlow, which provides programmers with a framework to manage data in real-time. It allows users to upload data into a relational database (MySQL), and to create custom scripts in high-level languages such as R, Python, or Perl for processing, correcting and modeling this data. CoreFlow organizes these scripts into project-specific pipelines, tracks interdependencies between related tasks, and enables the generation of summary reports as well as publication-quality images. As a result, the gap between experimental and computational components of a typical large-scale biology project is reduced, decreasing the time between data generation, analysis and manuscript writing. CoreFlow is being released to the scientific community as an open-sourced software package complete with proteomics-specific examples, which include corrections for incomplete isotopic labeling of peptides (SILAC) or arginine-to-proline conversion, and modeling of multiple/selected reaction monitoring (MRM/SRM) results. CoreFlow was purposely designed as an environment for programmers to rapidly perform data analysis. These analyses are assembled into project-specific workflows that are readily shared with biologists to guide the next stages of experimentation. Its simple yet powerful interface provides a structure where scripts can be written and tested virtually simultaneously to shorten the life cycle of code development for a particular task. The scripts are exposed at every step so that a user can quickly see the relationships between the data, the assumptions that have been made, and the manipulations that have been performed. Since the scripts use commonly available programming languages, they can easily be transferred to and from other computational environments for debugging or faster processing. This focus on 'on the fly' analysis sets CoreFlow apart from other workflow applications that require wrapping of scripts into particular formats and development of specific user interfaces. Importantly, current and future releases of data analysis scripts in CoreFlow format will be of widespread benefit to the proteomics community, not only for uptake and use in individual labs, but to enable full scrutiny of all analysis steps, thus increasing experimental reproducibility and decreasing errors. This article is part of a Special Issue entitled: Can Proteomics Fill the Gap Between Genomics and Phenotypes? Copyright © 2014 Elsevier B.V. All rights reserved.

RALPH: An online computer program for acquisition and reduction of pulse height data

NASA Technical Reports Server (NTRS)

Davies, R. C.; Clark, R. S.; Keith, J. E.

1973-01-01

A background/foreground data acquisition and analysis system incorporating a high level control language was developed for acquiring both singles and dual parameter coincidence data from scintillation detectors at the Radiation Counting Laboratory at the NASA Manned Spacecraft Center in Houston, Texas. The system supports acquisition of gamma ray spectra in a 256 x 256 coincidence matrix (utilizing disk storage) and simultaneous operation of any of several background support and data analysis functions. In addition to special instruments and interfaces, the hardware consists of a PDP-9 with 24K core memory, 256K words of disk storage, and Dectape and Magtape bulk storage.

Junior High Environmental and Outdoor Education: Teacher

ERIC Educational Resources Information Center

Alberta Dept. of Education, Edmonton. Curriculum Branch.

This manual for Junior High Environmental and Outdoor Education courses specifically addresses the special needs of adolescent students. A program development model is organized around six elements: (1) outdoor core; (2) personal and group development; (3) environmental core; (4) outdoor expeditions; (5) environmental investigations; and (6)…

INFN-Pisa scientific computation environment (GRID, HPC and Interactive Analysis)

NASA Astrophysics Data System (ADS)

Arezzini, S.; Carboni, A.; Caruso, G.; Ciampa, A.; Coscetti, S.; Mazzoni, E.; Piras, S.

2014-06-01

The INFN-Pisa Tier2 infrastructure is described, optimized not only for GRID CPU and Storage access, but also for a more interactive use of the resources in order to provide good solutions for the final data analysis step. The Data Center, equipped with about 6700 production cores, permits the use of modern analysis techniques realized via advanced statistical tools (like RooFit and RooStat) implemented in multicore systems. In particular a POSIX file storage access integrated with standard SRM access is provided. Therefore the unified storage infrastructure is described, based on GPFS and Xrootd, used both for SRM data repository and interactive POSIX access. Such a common infrastructure allows a transparent access to the Tier2 data to the users for their interactive analysis. The organization of a specialized many cores CPU facility devoted to interactive analysis is also described along with the login mechanism integrated with the INFN-AAI (National INFN Infrastructure) to extend the site access and use to a geographical distributed community. Such infrastructure is used also for a national computing facility in use to the INFN theoretical community, it enables a synergic use of computing and storage resources. Our Center initially developed for the HEP community is now growing and includes also HPC resources fully integrated. In recent years has been installed and managed a cluster facility (1000 cores, parallel use via InfiniBand connection) and we are now updating this facility that will provide resources for all the intermediate level HPC computing needs of the INFN theoretical national community.

The competencies required by professional hospice palliative care spiritual care providers.

PubMed

Cooper, Dan; Aherne, Michael; Pereira, José

2010-07-01

The Canadian Hospice Palliative Care Association (2002) identifies spiritual care of the dying and their families as a core service for Hospice Palliative Care programs. Yet, until the Spiritual Care Development Initiative of the Canadian Pallium Project, there was no published literature indicating systematic profiling of occupationally relevant core competencies or competency-based training programs specific to this specialized field of practice. This article describes a Canadian Community of Practice process to develop an occupational analysis-based competency profile for the Professional Hospice Palliative Care Spiritual Care Provider utilizing a modified Developing a Curriculum (DACUM) methodology. Competency profiles are important contributions to the development of curricula to train care providers who are recognized by other professions and by institutions as possessing the requisite theoretical and clinical expertise, particularly in academic tertiary care settings.

Vocational Didactics: Core Assumptions and Approaches from Denmark, Germany, Norway, Spain and Sweden

ERIC Educational Resources Information Center

Gessler, Michael; Moreno Herrera, Lázaro

2015-01-01

The design of vocational didactics has to meet special requirements. Six core assumptions are identified: outcome orientation, cultural-historical embedding, horizontal structure, vertical structure, temporal structure, and the changing nature of work. Different approaches and discussions from school-based systems (Spain and Sweden) and dual…

Polarimetric Thomson scattering for high Te fusion plasmas

NASA Astrophysics Data System (ADS)

Giudicotti, L.

2017-11-01

Polarimetric Thomson scattering (TS) is a technique for the analysis of TS spectra in which the electron temperature Te is determined from the depolarization of the scattered radiation, a relativistic effect noticeable only in very hot (Te >= 10 keV) fusion plasmas. It has been proposed as a complementary technique to supplement the conventional spectral analysis in the ITER CPTS (Core Plasma Thomson Scattering) system for measurements in high Te, low ne plasma conditions. In this paper we review the characteristics of the depolarized TS radiation with special emphasis to the conditions of the ITER CPTS system and we describe a possible implementation of this diagnostic method suitable to significantly improve the performances of the conventional TS spectral analysis in the high Te range.

Nuclear core positioning system

DOEpatents

Garkisch, Hans D.; Yant, Howard W.; Patterson, John F.

1979-01-01

A structural support system for the core of a nuclear reactor which achieves relatively restricted clearances at operating conditions and yet allows sufficient clearance between fuel assemblies at refueling temperatures. Axially displaced spacer pads having variable between pad spacing and a temperature compensated radial restraint system are utilized to maintain clearances between the fuel elements. The core support plates are constructed of metals specially chosen such that differential thermal expansion produces positive restraint at operating temperatures.

Ex-Vessel Core Melt Modeling Comparison between MELTSPREAD-CORQUENCH and MELCOR 2.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robb, Kevin R.; Farmer, Mitchell; Francis, Matthew W.

System-level code analyses by both United States and international researchers predict major core melting, bottom head failure, and corium-concrete interaction for Fukushima Daiichi Unit 1 (1F1). Although system codes such as MELCOR and MAAP are capable of capturing a wide range of accident phenomena, they currently do not contain detailed models for evaluating some ex-vessel core melt behavior. However, specialized codes containing more detailed modeling are available for melt spreading such as MELTSPREAD as well as long-term molten corium-concrete interaction (MCCI) and debris coolability such as CORQUENCH. In a preceding study, Enhanced Ex-Vessel Analysis for Fukushima Daiichi Unit 1: Meltmore » Spreading and Core-Concrete Interaction Analyses with MELTSPREAD and CORQUENCH, the MELTSPREAD-CORQUENCH codes predicted the 1F1 core melt readily cooled in contrast to predictions by MELCOR. The user community has taken notice and is in the process of updating their systems codes; specifically MAAP and MELCOR, to improve and reduce conservatism in their ex-vessel core melt models. This report investigates why the MELCOR v2.1 code, compared to the MELTSPREAD and CORQUENCH 3.03 codes, yield differing predictions of ex-vessel melt progression. To accomplish this, the differences in the treatment of the ex-vessel melt with respect to melt spreading and long-term coolability are examined. The differences in modeling approaches are summarized, and a comparison of example code predictions is provided.« less

Comparative Genomic Analysis of Drechmeria coniospora Reveals Core and Specific Genetic Requirements for Fungal Endoparasitism of Nematodes

PubMed Central

Thakur, Nishant; Arguel, Marie-Jeanne; Polanowska, Jolanta; Henrissat, Bernard; Record, Eric; Magdelenat, Ghislaine; Barbe, Valérie; Raffaele, Sylvain; Barbry, Pascal

2016-01-01

Drechmeria coniospora is an obligate fungal pathogen that infects nematodes via the adhesion of specialized spores to the host cuticle. D. coniospora is frequently found associated with Caenorhabditis elegans in environmental samples. It is used in the study of the nematode’s response to fungal infection. Full understanding of this bi-partite interaction requires knowledge of the pathogen’s genome, analysis of its gene expression program and a capacity for genetic engineering. The acquisition of all three is reported here. A phylogenetic analysis placed D. coniospora close to the truffle parasite Tolypocladium ophioglossoides, and Hirsutella minnesotensis, another nematophagous fungus. Ascomycete nematopathogenicity is polyphyletic; D. coniospora represents a branch that has not been molecularly characterized. A detailed in silico functional analysis, comparing D. coniospora to 11 fungal species, revealed genes and gene families potentially involved in virulence and showed it to be a highly specialized pathogen. A targeted comparison with nematophagous fungi highlighted D. coniospora-specific genes and a core set of genes associated with nematode parasitism. A comparative gene expression analysis of samples from fungal spores and mycelia, and infected C. elegans, gave a molecular view of the different stages of the D. coniospora lifecycle. Transformation of D. coniospora allowed targeted gene knock-out and the production of fungus that expresses fluorescent reporter genes. It also permitted the initial characterisation of a potential fungal counter-defensive strategy, involving interference with a host antimicrobial mechanism. This high-quality annotated genome for D. coniospora gives insights into the evolution and virulence of nematode-destroying fungi. Coupled with genetic transformation, it opens the way for molecular dissection of D. coniospora physiology, and will allow both sides of the interaction between D. coniospora and C. elegans, as well as the evolutionary arms race that exists between pathogen and host, to be studied. PMID:27153332

Science Education for Students with Special Needs

ERIC Educational Resources Information Center

Villanueva, Mary Grace; Taylor, Jonte; Therrien, William; Hand, Brian

2012-01-01

Students with special needs tend to show significantly lower achievement in science than their peers. Reasons for this include severe difficulties with academic skills (i.e. reading, math and writing), behaviour problems and limited prior understanding of core concepts background knowledge. Despite this bleak picture, much is known on how to…

Special Educators' Perceptions of State Standards in a Large, Urban School District

ERIC Educational Resources Information Center

Cramer, Elizabeth D.; Gallo, Rosalia F.

2017-01-01

The implementation of Common Core State Standards raises challenges for teachers, particularly those in urban settings and those who work with students with unique learning challenges, particularly students with disabilities. This article provides the results of a study that surveyed special education teachers' perspectives related to the…

Special Education and the P-16 Initiative: Addressing CEC Competencies through Portfolio Development and Assessment.

ERIC Educational Resources Information Center

Kenney, Stephanie L.; Hammitte, Diana J.; Rakestraw, Jennie; LaMontagne, M. J.

2000-01-01

This article discusses how Georgia Southern University redesigned its special education teacher curriculum to reflect the core competencies identified by the Council for Exceptional Children, the Georgia Professional Standards Commission, and the National Collegiate Accreditation for Teacher Education. Portfolio assessment procedures were…

Seismic waves and earthquakes in a global monolithic model

NASA Astrophysics Data System (ADS)

Roubíček, Tomáš

2018-03-01

The philosophy that a single "monolithic" model can "asymptotically" replace and couple in a simple elegant way several specialized models relevant on various Earth layers is presented and, in special situations, also rigorously justified. In particular, global seismicity and tectonics is coupled to capture, e.g., (here by a simplified model) ruptures of lithospheric faults generating seismic waves which then propagate through the solid-like mantle and inner core both as shear (S) or pressure (P) waves, while S-waves are suppressed in the fluidic outer core and also in the oceans. The "monolithic-type" models have the capacity to describe all the mentioned features globally in a unified way together with corresponding interfacial conditions implicitly involved, only when scaling its parameters appropriately in different Earth's layers. Coupling of seismic waves with seismic sources due to tectonic events is thus an automatic side effect. The global ansatz is here based, rather for an illustration, only on a relatively simple Jeffreys' viscoelastic damageable material at small strains whose various scaling (limits) can lead to Boger's viscoelastic fluid or even to purely elastic (inviscid) fluid. Self-induced gravity field, Coriolis, centrifugal, and tidal forces are counted in our global model, as well. The rigorous mathematical analysis as far as the existence of solutions, convergence of the mentioned scalings, and energy conservation is briefly presented.

A Rural County Journeys to the Common Core

ERIC Educational Resources Information Center

Ceballos, Pansy T.

2012-01-01

Small, rural school districts face a special challenge when implementing the next generation of academic standards known as the Common Core State Standards. This is the task facing the instructional consultants with the Tulare County Office of Education. The county, located in central California with its dominant agricultural economy, has 45…

Impact of Work Awareness Instruction for Adolescents with Special Needs.

ERIC Educational Resources Information Center

Black, Rhonda S.

A work awareness curriculum designed to help disabled students develop the core social skills critical to success in the workplace was developed and presented to disabled students in two states. The core social skills were identified in a literature review. The curriculum included activities to increase students' awareness of often-unstated…

Using Sentence Frames to Develop Academic Vocabulary for English Learners

ERIC Educational Resources Information Center

Donnelly, Whitney Bray; Roe, Christopher J.

2010-01-01

Often, English-language development (ELD) is taught during a dedicated time of the school day. There is often a mismatch between the content of ELD and the lessons taught during core instruction provided during the remainder of the day. During core instruction, teachers use specially designed academic instruction in English strategies to ensure…

Development of an extensible dual-core wireless sensing node for cyber-physical systems

NASA Astrophysics Data System (ADS)

Kane, Michael; Zhu, Dapeng; Hirose, Mitsuhito; Dong, Xinjun; Winter, Benjamin; Häckell, Mortiz; Lynch, Jerome P.; Wang, Yang; Swartz, A.

2014-04-01

The introduction of wireless telemetry into the design of monitoring and control systems has been shown to reduce system costs while simplifying installations. To date, wireless nodes proposed for sensing and actuation in cyberphysical systems have been designed using microcontrollers with one computational pipeline (i.e., single-core microcontrollers). While concurrent code execution can be implemented on single-core microcontrollers, concurrency is emulated by splitting the pipeline's resources to support multiple threads of code execution. For many applications, this approach to multi-threading is acceptable in terms of speed and function. However, some applications such as feedback controls demand deterministic timing of code execution and maximum computational throughput. For these applications, the adoption of multi-core processor architectures represents one effective solution. Multi-core microcontrollers have multiple computational pipelines that can execute embedded code in parallel and can be interrupted independent of one another. In this study, a new wireless platform named Martlet is introduced with a dual-core microcontroller adopted in its design. The dual-core microcontroller design allows Martlet to dedicate one core to standard wireless sensor operations while the other core is reserved for embedded data processing and real-time feedback control law execution. Another distinct feature of Martlet is a standardized hardware interface that allows specialized daughter boards (termed wing boards) to be interfaced to the Martlet baseboard. This extensibility opens opportunity to encapsulate specialized sensing and actuation functions in a wing board without altering the design of Martlet. In addition to describing the design of Martlet, a few example wings are detailed, along with experiments showing the Martlet's ability to monitor and control physical systems such as wind turbines and buildings.

NATCRCTR: One-dimensional thermal-hydraulics analysis code for natural-circulation TRIGA reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feltus, M.A.; Rubinaccio, G.

1996-12-31

The Pennsylvania State University nuclear engineering department is evaluating the upgrade of the Reed College (Portland, Oregon) TRIGA reactor from 250 kW to 1 MW in two areas: thermal-hydraulics and steady-state neutronics analysis. This analysis was initiated as a cooperative effort between Penn State and Reed College as a training project for two International Atomic Energy Agency (IAEA) fellows from Ghana. The two Ghanaian IAEA fellows were assisted by G. Rubinaccio, an undergraduate, who undertook the task of writing the new computer programs for the thermal-hydraulic and physics evaluation as a three-credit special design project course. The Reed College TRIGA,more » which has a fixed graphite radial reflector, is cooled by natural circulation, without external cross-flow; whereas, the Penn State Breazeale Reactor has significant crossflow into its sides. To model the Reed TRIGA, the NATCRCTR program has been developed from first principles using the following assumptions: 1. The core is surrounded by the fixed reflector structure, which acts as a one-dimensional channel. 2. The core inlet temperature distribution is constant at the core bottom. 3. The axial heat flux distribution is a chopped cosine shape. 4. The heat transfer in the fuel is primarily in the radial directions. 5. A small gap between the fuel and cladding exists. The NATCRCTR code is used to find the peak centerline fuel, gap, and cladding surface temperatures, based on assumed flux and engineering peaking factors.« less

Hyper Text Mark-up Language and Dublin Core metadata element set usage in websites of Iranian State Universities' libraries.

PubMed

Zare-Farashbandi, Firoozeh; Ramezan-Shirazi, Mahtab; Ashrafi-Rizi, Hasan; Nouri, Rasool

2014-01-01

Recent progress in providing innovative solutions in the organization of electronic resources and research in this area shows a global trend in the use of new strategies such as metadata to facilitate description, place for, organization and retrieval of resources in the web environment. In this context, library metadata standards have a special place; therefore, the purpose of the present study has been a comparative study on the Central Libraries' Websites of Iran State Universities for Hyper Text Mark-up Language (HTML) and Dublin Core metadata elements usage in 2011. The method of this study is applied-descriptive and data collection tool is the check lists created by the researchers. Statistical community includes 98 websites of the Iranian State Universities of the Ministry of Health and Medical Education and Ministry of Science, Research and Technology and method of sampling is the census. Information was collected through observation and direct visits to websites and data analysis was prepared by Microsoft Excel software, 2011. The results of this study indicate that none of the websites use Dublin Core (DC) metadata and that only a few of them have used overlaps elements between HTML meta tags and Dublin Core (DC) elements. The percentage of overlaps of DC elements centralization in the Ministry of Health were 56% for both description and keywords and, in the Ministry of Science, were 45% for the keywords and 39% for the description. But, HTML meta tags have moderate presence in both Ministries, as the most-used elements were keywords and description (56%) and the least-used elements were date and formatter (0%). It was observed that the Ministry of Health and Ministry of Science follows the same path for using Dublin Core standard on their websites in the future. Because Central Library Websites are an example of scientific web pages, special attention in designing them can help the researchers to achieve faster and more accurate information resources. Therefore, the influence of librarians' ideas on the awareness of web designers and developers will be important for using metadata elements as general, and specifically for applying such standards.

Hyper Text Mark-up Language and Dublin Core metadata element set usage in websites of Iranian State Universities’ libraries

PubMed Central

Zare-Farashbandi, Firoozeh; Ramezan-Shirazi, Mahtab; Ashrafi-Rizi, Hasan; Nouri, Rasool

2014-01-01

Introduction: Recent progress in providing innovative solutions in the organization of electronic resources and research in this area shows a global trend in the use of new strategies such as metadata to facilitate description, place for, organization and retrieval of resources in the web environment. In this context, library metadata standards have a special place; therefore, the purpose of the present study has been a comparative study on the Central Libraries’ Websites of Iran State Universities for Hyper Text Mark-up Language (HTML) and Dublin Core metadata elements usage in 2011. Materials and Methods: The method of this study is applied-descriptive and data collection tool is the check lists created by the researchers. Statistical community includes 98 websites of the Iranian State Universities of the Ministry of Health and Medical Education and Ministry of Science, Research and Technology and method of sampling is the census. Information was collected through observation and direct visits to websites and data analysis was prepared by Microsoft Excel software, 2011. Results: The results of this study indicate that none of the websites use Dublin Core (DC) metadata and that only a few of them have used overlaps elements between HTML meta tags and Dublin Core (DC) elements. The percentage of overlaps of DC elements centralization in the Ministry of Health were 56% for both description and keywords and, in the Ministry of Science, were 45% for the keywords and 39% for the description. But, HTML meta tags have moderate presence in both Ministries, as the most-used elements were keywords and description (56%) and the least-used elements were date and formatter (0%). Conclusion: It was observed that the Ministry of Health and Ministry of Science follows the same path for using Dublin Core standard on their websites in the future. Because Central Library Websites are an example of scientific web pages, special attention in designing them can help the researchers to achieve faster and more accurate information resources. Therefore, the influence of librarians’ ideas on the awareness of web designers and developers will be important for using metadata elements as general, and specifically for applying such standards. PMID:24741646

The Dilemma of Inclusion: Is Full Inclusion Ethical? An Examination of the Culture of Special Education within a Semi-Rural Pre-K to Sixth Grade Elementary School District

ERIC Educational Resources Information Center

Press, Kandie A.

2010-01-01

At its core the political push for full inclusion models of special education delivery derives from the belief that inclusion provides equal access, equitable distribution of resources and increased social opportunity to children. This study focused upon the evolution of special education programming within a pre-K to sixth grade elementary school…

VISCEL: A general-purpose computer program for analysis of linear viscoelastic structures (user's manual), volume 1

NASA Technical Reports Server (NTRS)

Gupta, K. K.; Akyuz, F. A.; Heer, E.

1972-01-01

This program, an extension of the linear equilibrium problem solver ELAS, is an updated and extended version of its earlier form (written in FORTRAN 2 for the IBM 7094 computer). A synchronized material property concept utilizing incremental time steps and the finite element matrix displacement approach has been adopted for the current analysis. A special option enables employment of constant time steps in the logarithmic scale, thereby reducing computational efforts resulting from accumulative material memory effects. A wide variety of structures with elastic or viscoelastic material properties can be analyzed by VISCEL. The program is written in FORTRAN 5 language for the Univac 1108 computer operating under the EXEC 8 system. Dynamic storage allocation is automatically effected by the program, and the user may request up to 195K core memory in a 260K Univac 1108/EXEC 8 machine. The physical program VISCEL, consisting of about 7200 instructions, has four distinct links (segments), and the compiled program occupies a maximum of about 11700 words decimal of core storage.

Special Education: Program of Studies for Senior High School, Core IV.

ERIC Educational Resources Information Center

Forsyth County - Winston-Salem City Schools, NC.

A curriculum guide for senior high school educable retarded pupils, based on activities undertaken during the first 2 years of the special program, is oriented toward job training and preparation. Purposes, course structure, and objectives are given for each of the following areas of study: arts and crafts, binding, business practice, driver…

Special Planning for Special Spaces. Selected Articles from "Planning for Higher Education."

ERIC Educational Resources Information Center

Rickes, Persis, Ed.

This collection contains articles from the journal "Planning for Higher Education" organized around four core spaces commonly found on a college or university campus. Following an introduction, Section 2, "Cultural Spaces," contains these articles: (1) "Planning the Successful Performing Arts Facility" (Wendell Brase, v18 n3); (2) "Frontier…

Restructuring Vocational Special Needs Education through Interdisciplinary Team Effort: Local Motion in the Pacific Basin.

ERIC Educational Resources Information Center

Smith, Garnett J.; Stodden, Robert A.

1994-01-01

The Restructuring through Interdisciplinary Team Effort project focuses on changing the culture and structure of vocational special needs education in the Pacific Basin. Its three dimensions are cognitive core (best practices, outcome-focused design, strategic planning); team network of stakeholders; and systemic renewal (school-to-work…

Instructional Scaffolds for Learning from Formative Peer Assessment: Effects of Core Task, Peer Feedback, and Dialogue

ERIC Educational Resources Information Center

Deiglmayr, Anne

2018-01-01

Formative peer assessment is an instructional method that offers many opportunities to foster students' learning with respect to both the domain of the core task and students' assessment skills. The contributions to this special issue effectively address earlier calls for more research into instructional scaffolds and the implementation of…

Counselor Preparation: Reimagining Counselor Education with Diversity as a Core Value

ERIC Educational Resources Information Center

Stadler, Holly A.; Cobia, Debra C.; Middleton, Renee A.; Carney, Jamie S.

2006-01-01

To move diversity from the periphery of counselor preparation to its core requires effort beyond the 1 or 2 "special" courses that have been the main stay of multicultural counselor education (T. E. Midgette & S. S. Meggert, 1991). The authors describe the processes and outcomes of a systemic reimagining of Auburn University's counselor education…

34 CFR 365.21 - What funds may the State use to provide the IL core services?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true What funds may the State use to provide the IL core services? 365.21 Section 365.21 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION STATE...

Common Core Preparation in Special Education Teacher Education Programs: Beginning the Conversation

ERIC Educational Resources Information Center

Murphy, Michelle R.; Marshall, Kathleen J.

2015-01-01

The Common Core State Standards (CCSS) were developed to encourage a common focus of instruction and evaluation in the areas of mathematics, reading/language arts, writing, speaking, and listening. As of 2011, all but five states have adopted CCSS for math and English Language Arts (ELA), with another adopting only the standards for ELA. With…

Fast multi-core based multimodal registration of 2D cross-sections and 3D datasets.

PubMed

Scharfe, Michael; Pielot, Rainer; Schreiber, Falk

2010-01-11

Solving bioinformatics tasks often requires extensive computational power. Recent trends in processor architecture combine multiple cores into a single chip to improve overall performance. The Cell Broadband Engine (CBE), a heterogeneous multi-core processor, provides power-efficient and cost-effective high-performance computing. One application area is image analysis and visualisation, in particular registration of 2D cross-sections into 3D image datasets. Such techniques can be used to put different image modalities into spatial correspondence, for example, 2D images of histological cuts into morphological 3D frameworks. We evaluate the CBE-driven PlayStation 3 as a high performance, cost-effective computing platform by adapting a multimodal alignment procedure to several characteristic hardware properties. The optimisations are based on partitioning, vectorisation, branch reducing and loop unrolling techniques with special attention to 32-bit multiplies and limited local storage on the computing units. We show how a typical image analysis and visualisation problem, the multimodal registration of 2D cross-sections and 3D datasets, benefits from the multi-core based implementation of the alignment algorithm. We discuss several CBE-based optimisation methods and compare our results to standard solutions. More information and the source code are available from http://cbe.ipk-gatersleben.de. The results demonstrate that the CBE processor in a PlayStation 3 accelerates computational intensive multimodal registration, which is of great importance in biological/medical image processing. The PlayStation 3 as a low cost CBE-based platform offers an efficient option to conventional hardware to solve computational problems in image processing and bioinformatics.

Experiences of Patient-Centredness With Specialized Community-Based Care

PubMed Central

Winsor, S; Smith, A; Vanstone, M; Giacomini, M; Brundisini, FK; DeJean, D

2013-01-01

Background Specialized community-based care (SCBC) endeavours to help patients manage chronic diseases by formalizing the link between primary care providers and other community providers with specialized training. Many types of health care providers and community-based programs are employed in SCBC. Patient-centred care focuses on patients’ psychosocial experience of health and illness to ensure that patients’ care plans are modelled on their individual values, preferences, spirituality, and expressed needs. Objectives To synthesize qualitative research on patient and provider experiences of SCBC interventions and health care delivery models, using the core principles of patient-centredness. Data Sources This report synthesizes 29 primary qualitative studies on the topic of SCBC interventions for patients with chronic conditions. Included studies were published between 2002 and 2012, and followed adult patients in North America, Europe, Australia, and New Zealand. Review Methods Qualitative meta-synthesis was used to integrate findings across primary research studies. Results Three core themes emerged from the analysis: patients’ health beliefs affect their participation in SCBC interventions; patients’ experiences with community-based care differ from their experiences with hospital-based care; patients and providers value the role of nurses differently in community-based chronic disease care. Limitations Qualitative research findings are not intended to generalize directly to populations, although meta-synthesis across several qualitative studies builds an increasingly robust understanding that is more likely to be transferable. The diversity of interventions that fall under SCBC and the cross-interventional focus of many of the studies mean that findings might not be generalizable to all forms of SCBC or its specific components. Conclusions Patients with chronic diseases who participated in SCBC interventions reported greater satisfaction when SCBC helped them better understand their diagnosis, facilitated increased socialization, provided them with a role in managing their own care, and assisted them in overcoming psychological and social barriers. Plain Language Summary More and more, to reduce bed shortages in hospitals, health care systems are providing programs called specialized community-based care (SCBC) to patients with chronic diseases. These SCBC programs allow patients with chronic diseases to be managed in the community by linking their family physicians with other community-based health care providers who have specialized training. This report looks at the experiences of patients and health care providers who take part in SCBC programs, focusing on psychological and social factors. This kind of lens is called patient-centred. Three themes came up in our analysis: patients’ health beliefs affect how they take part in SCBC interventions; patients’ experiences with care in the community differ from their experiences with care in the hospital; patients and providers value the role of nurses differently. The results of this analysis could help those who provide SCBC programs to better meet patients’ needs. PMID:24228080

Experiences of patient-centredness with specialized community-based care: a systematic review and qualitative meta-synthesis.

PubMed

Winsor, S; Smith, A; Vanstone, M; Giacomini, M; Brundisini, F K; DeJean, D

2013-01-01

Specialized community-based care (SCBC) endeavours to help patients manage chronic diseases by formalizing the link between primary care providers and other community providers with specialized training. Many types of health care providers and community-based programs are employed in SCBC. Patient-centred care focuses on patients' psychosocial experience of health and illness to ensure that patients' care plans are modelled on their individual values, preferences, spirituality, and expressed needs. To synthesize qualitative research on patient and provider experiences of SCBC interventions and health care delivery models, using the core principles of patient-centredness. This report synthesizes 29 primary qualitative studies on the topic of SCBC interventions for patients with chronic conditions. Included studies were published between 2002 and 2012, and followed adult patients in North America, Europe, Australia, and New Zealand. Qualitative meta-synthesis was used to integrate findings across primary research studies. Three core themes emerged from the analysis: patients' health beliefs affect their participation in SCBC interventions;patients' experiences with community-based care differ from their experiences with hospital-based care;patients and providers value the role of nurses differently in community-based chronic disease care. Qualitative research findings are not intended to generalize directly to populations, although meta-synthesis across several qualitative studies builds an increasingly robust understanding that is more likely to be transferable. The diversity of interventions that fall under SCBC and the cross-interventional focus of many of the studies mean that findings might not be generalizable to all forms of SCBC or its specific components. Patients with chronic diseases who participated in SCBC interventions reported greater satisfaction when SCBC helped them better understand their diagnosis, facilitated increased socialization, provided them with a role in managing their own care, and assisted them in overcoming psychological and social barriers. More and more, to reduce bed shortages in hospitals, health care systems are providing programs called specialized community-based care (SCBC) to patients with chronic diseases. These SCBC programs allow patients with chronic diseases to be managed in the community by linking their family physicians with other community-based health care providers who have specialized training. This report looks at the experiences of patients and health care providers who take part in SCBC programs, focusing on psychological and social factors. This kind of lens is called patient-centred. Three themes came up in our analysis: patients' health beliefs affect how they take part in SCBC interventions; patients' experiences with care in the community differ from their experiences with care in the hospital; patients and providers value the role of nurses differently. The results of this analysis could help those who provide SCBC programs to better meet patients' needs.

ZnSe based semiconductor core-shell structures: From preparation to application

NASA Astrophysics Data System (ADS)

Sun, Chengcheng; Gu, Yarong; Wen, Weijia; Zhao, Lijuan

2018-07-01

Inorganic core-shell semiconductor materials have attracted increasing interest in recent years because of the unique structure, stable chemical properties and high performance in devices. With special properties such as a direct band-gap and excellent photoelectrical characteristics, ZnSe based semiconductor core-shell structures are promising materials for applications in such fields as photocatalysts, light-emitting diodes, solar cells, photodetectors, biomedical science and so on. However, few reviews on ZnSe based semiconductor core-shell structures have been reported so far. Therefore this manuscript mainly focuses on the research activities on ZnSe based semiconductor core-shell composites including various preparation methods and the applications of these core-shell structures, especially in photocatalysts, light emitting, solar cells and photodetectors. The possibilities and limitations of studies on ZnSe based semiconductor core-shell composites are also highlighted.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wagner, B.

A specially designed wire line retrievable continuous coring system cored its initial project wells to total depth in hard rock formations in less than half the time that would have been required by conventional coring rigs. The hybrid wire line coring systems have since been used on other wells in similar lithologies, with a total of 38,000 m (124,640 ft) of hole cored and with penetration rates averaging 2.27 m/hr (7.45 ft/hr). This paper reports that Parker Drilling Co. designed the hybrid rigs and has recently been contracted to wire line core several holes for oil and gas exploration inmore » the Congo. The first core hole has been completed to 1,490 m, and total depth was reached in 21 days. The rig is now being mobilized to a second hole in the Congo.« less

Skilled interaction among professional carers in special accommodations for adult people with learning disabilities.

PubMed

Antonsson, H; Aström, S; Lundström, M; Graneheim, U H

2013-09-01

Communicative difficulties affect interactions between people with learning disabilities and their carers. Despite such difficulties, however, some carers seem to interact successfully with people who have limited ability to communicate verbally and exhibit challenging behaviour. This study aims to illuminate skilled interaction among carers working in special accommodations for people with learning disabilities. Interactions between 16 caregivers and 11 residents with learning disabilities were recorded on video. Verbal and non-verbal interaction skills among the carers were identified. Four caring situations with people with learning disabilities were chosen to illuminate skilled interaction. The transcribed text was subjected to qualitative content analysis and core stories were created. The results show that skilled interaction between the carers and the people with learning disabilities is based upon being confirming, sharing daily life experience, giving time and space, and using congruent and distinct language. In this paper we present examples that offer concrete suggestions of how to promote successful interaction and create meaning in the shared day-to-day life in special accommodations for people with learning disabilities. © 2012 John Wiley & Sons Ltd.

Evidence for Updating the Core Domain Set of Outcome Measures for Juvenile Idiopathic Arthritis: Report from a Special Interest Group at OMERACT 2016.

PubMed

Morgan, Esi M; Riebschleger, Meredith P; Horonjeff, Jennifer; Consolaro, Alessandro; Munro, Jane E; Thornhill, Susan; Beukelman, Timothy; Brunner, Hermine I; Creek, Emily L; Harris, Julia G; Horton, Daniel B; Lovell, Daniel J; Mannion, Melissa L; Olson, Judyann C; Rahimi, Homaira; Gallo, Maria Chiara; Calandra, Serena; Ravelli, Angelo; Ringold, Sarah; Shenoi, Susan; Stinson, Jennifer; Toupin-April, Karine; Strand, Vibeke; Bingham, Clifton O

2017-12-01

The current Juvenile Idiopathic Arthritis (JIA) Core Set was developed in 1997 to identify the outcome measures to be used in JIA clinical trials using statistical and consensus-based techniques, but without patient involvement. The importance of patient/parent input into the research process has increasingly been recognized over the years. An Outcome Measures in Rheumatology (OMERACT) JIA Core Set Working Group was formed to determine whether the outcome domains of the current core set are relevant to those involved or whether the core set domains should be revised. Twenty-four people from the United States, Canada, Australia, and Europe, including patient partners, formed the working group. Guided by the OMERACT Filter 2.0 process, we performed (1) a systematic literature review of outcome domains, (2) a Web-based survey (142 patients, 343 parents), (3) an idea-generation study (120 parents), (4) 4 online discussion boards (24 patients, 20 parents), and (5) a Special Interest Group (SIG) activity at the OMERACT 13 (2016) meeting. A MEDLINE search of outcome domains used in studies of JIA yielded 5956 citations, of which 729 citations underwent full-text review, and identified additional domains to those included in the current JIA Core Set. Qualitative studies on the effect of JIA identified multiple additional domains, including pain and participation. Twenty-one participants in the SIG achieved consensus on the need to revise the entire JIA Core Set. The results of qualitative studies and literature review support the need to expand the JIA Core Set, considering, among other things, additional patient/parent-centered outcomes, clinical data, and imaging data.

A radiographic scanning technique for cores

USGS Publications Warehouse

Hill, G.W.; Dorsey, M.E.; Woods, J.C.; Miller, R.J.

1979-01-01

A radiographic scanning technique (RST) can produce single continuous radiographs of cores or core sections up to 1.5 m long and up to 30 cm wide. Changing a portable industrial X-ray unit from the normal still-shot mode to a scanning mode requires simple, inexpensive, easily constructed, and highly durable equipment. Additional components include a conveyor system, antiscatter cylinder-diaphragm, adjustable sample platform, developing tanks, and a contact printer. Complete cores, half cores, sample slabs or peels may be scanned. Converting the X-ray unit from one mode to another is easy and can be accomplished without the use of special tools. RST provides the investigator with a convenient, continuous, high quality radiograph, saves time and money, and decreases the number of times cores have to be handled. ?? 1979.

Equilibrium cycle pin by pin transport depletion calculations with DeCART

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kochunas, B.; Downar, T.; Taiwo, T.

As the Advanced Fuel Cycle Initiative (AFCI) program has matured it has become more important to utilize more advanced simulation methods. The work reported here was performed as part of the AFCI fellowship program to develop and demonstrate the capability of performing high fidelity equilibrium cycle calculations. As part of the work here, a new multi-cycle analysis capability was implemented in the DeCART code which included modifying the depletion modules to perform nuclide decay calculations, implementing an assembly shuffling pattern description, and modifying iteration schemes. During the work, stability issues were uncovered with respect to converging simultaneously the neutron flux,more » isotopics, and fluid density and temperature distributions in 3-D. Relaxation factors were implemented which considerably improved the stability of the convergence. To demonstrate the capability two core designs were utilized, a reference UOX core and a CORAIL core. Full core equilibrium cycle calculations were performed on both cores and the discharge isotopics were compared. From this comparison it was noted that the improved modeling capability was not drastically different in its prediction of the discharge isotopics when compared to 2-D single assembly or 2-D core models. For fissile isotopes such as U-235, Pu-239, and Pu-241 the relative differences were 1.91%, 1.88%, and 0.59%), respectively. While this difference may not seem large it translates to mass differences on the order of tens of grams per assembly, which may be significant for the purposes of accounting of special nuclear material. (authors)« less

Dual Powerpoint Presentation Approach for Students with Special Educational Needs and Note-Takers

ERIC Educational Resources Information Center

Naik, Nitin

2017-01-01

In higher education, supporting students with special educational needs (SEN) necessitates an understanding of these needs, additional teaching aids and innovative ideas. The teacher must be an integral part of this support process, and this is difficult for the majority of teachers, due to their lack of core understanding of SEN. However,…

77 FR 6131 - National Institute of Diabetes and Digestive and Kidney Diseases Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-07

... Diabetes and Digestive and Kidney Diseases Notice of Closed Meetings Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; PAR09-247 Ancillary Studies in... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; George M. O'Brien Kidney Research Core...

Numerical studies of interacting vortices

NASA Technical Reports Server (NTRS)

Liu, G. C.; Hsu, C. H.

1985-01-01

To get a basic understanding of the physics of flowfields modeled by vortex filaments with finite vortical cores, systematic numerical studies of the interactions of two dimensional vortices and pairs of coaxial axisymmetric circular vortex rings were made. Finite difference solutions of the unsteady incompressible Navier-Stokes equations were carried out using vorticity and stream function as primary variables. Special emphasis was placed on the formulation of appropriate boundary conditions necessary for the calculations in a finite computational domain. Numerical results illustrate the interaction of vortex filaments, demonstrate when and how they merge with each other, and establish the region of validity for an asymptotic analysis.

Disparities in Access to Healthcare Transition Services for Adolescents with Down Syndrome.

PubMed

Nugent, James; Gorman, Gregory; Erdie-Lalena, Christine R

2018-06-01

To compare healthcare transition planning in adolescents with Down syndrome with adolescents with other special healthcare needs. Data were drawn from the 2009-2010 National Survey of Children with Special Health Care Needs, a nationally representative sample with 17 114 adolescents aged 12-17 years. Parents were asked whether providers and the study child had discussed shifting to an adult provider, changing healthcare needs, maintaining health insurance coverage, and taking responsibility for self-care. The transition core outcome was a composite measure based on the results of these 4 questions. Multivariable logistic regression determined the association between Down syndrome and the transition core outcome as well as each of the 4 individual component measures. Although 40% of adolescents with other special healthcare needs met the transition core outcome, 11.0% of adolescents with Down syndrome met this outcome. Adolescents with Down syndrome were less likely to be encouraged to take responsibility for their health (32.2% vs 78.4%). After adjustment for demographic, socioeconomic, and health-related factors, adolescents with Down syndrome had 4 times the odds of not meeting the transition core outcome. For the component measures, Down syndrome adolescents had 4 times the odds of not being encouraged to take responsibility for self-care. Medical home access increased the odds of transition preparation. Adolescents with Down syndrome experience disparities in access to transition services. Provider goals for adolescents with Down syndrome should encourage as much independence as possible in their personal care and social lives. Copyright © 2018 Elsevier Inc. All rights reserved.

Defining Tobacco Regulatory Science Competencies.

PubMed

Wipfli, Heather L; Berman, Micah; Hanson, Kacey; Kelder, Steven; Solis, Amy; Villanti, Andrea C; Ribeiro, Carla M P; Meissner, Helen I; Anderson, Roger

2017-02-01

In 2013, the National Institutes of Health and the Food and Drug Administration funded a network of 14 Tobacco Centers of Regulatory Science (TCORS) with a mission that included research and training. A cross-TCORS Panel was established to define tobacco regulatory science (TRS) competencies to help harmonize and guide their emerging educational programs. The purpose of this paper is to describe the Panel's work to develop core TRS domains and competencies. The Panel developed the list of domains and competencies using a semistructured Delphi method divided into four phases occurring between November 2013 and August 2015. The final proposed list included a total of 51 competencies across six core domains and 28 competencies across five specialized domains. There is a need for continued discussion to establish the utility of the proposed set of competencies for emerging TRS curricula and to identify the best strategies for incorporating these competencies into TRS training programs. Given the field's broad multidisciplinary nature, further experience is needed to refine the core domains that should be covered in TRS training programs versus knowledge obtained in more specialized programs. Regulatory science to inform the regulation of tobacco products is an emerging field. The paper provides an initial list of core and specialized domains and competencies to be used in developing curricula for new and emerging training programs aimed at preparing a new cohort of scientists to conduct critical TRS research. © The Author 2016. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Physical Connectivity Mapping by Circular Permutation of Human Telomerase RNA Reveals New Regions Critical for Activity and Processivity.

PubMed

Mefford, Melissa A; Zappulla, David C

2016-01-15

Telomerase is a specialized ribonucleoprotein complex that extends the 3' ends of chromosomes to counteract telomere shortening. However, increased telomerase activity is associated with ∼90% of human cancers. The telomerase enzyme minimally requires an RNA (hTR) and a specialized reverse transcriptase protein (TERT) for activity in vitro. Understanding the structure-function relationships within hTR has important implications for human disease. For the first time, we have tested the physical-connectivity requirements in the 451-nucleotide hTR RNA using circular permutations, which reposition the 5' and 3' ends. Our extensive in vitro analysis identified three classes of hTR circular permutants with altered function. First, circularly permuting 3' of the template causes specific defects in repeat-addition processivity, revealing that the template recognition element found in ciliates is conserved in human telomerase RNA. Second, seven circular permutations residing within the catalytically important core and CR4/5 domains completely abolish telomerase activity, unveiling mechanistically critical portions of these domains. Third, several circular permutations between the core and CR4/5 significantly increase telomerase activity. Our extensive circular permutation results provide insights into the architecture and coordination of human telomerase RNA and highlight where the RNA could be targeted for the development of antiaging and anticancer therapeutics. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

Physical Connectivity Mapping by Circular Permutation of Human Telomerase RNA Reveals New Regions Critical for Activity and Processivity

PubMed Central

Mefford, Melissa A.

2015-01-01

Telomerase is a specialized ribonucleoprotein complex that extends the 3′ ends of chromosomes to counteract telomere shortening. However, increased telomerase activity is associated with ∼90% of human cancers. The telomerase enzyme minimally requires an RNA (hTR) and a specialized reverse transcriptase protein (TERT) for activity in vitro. Understanding the structure-function relationships within hTR has important implications for human disease. For the first time, we have tested the physical-connectivity requirements in the 451-nucleotide hTR RNA using circular permutations, which reposition the 5′ and 3′ ends. Our extensive in vitro analysis identified three classes of hTR circular permutants with altered function. First, circularly permuting 3′ of the template causes specific defects in repeat-addition processivity, revealing that the template recognition element found in ciliates is conserved in human telomerase RNA. Second, seven circular permutations residing within the catalytically important core and CR4/5 domains completely abolish telomerase activity, unveiling mechanistically critical portions of these domains. Third, several circular permutations between the core and CR4/5 significantly increase telomerase activity. Our extensive circular permutation results provide insights into the architecture and coordination of human telomerase RNA and highlight where the RNA could be targeted for the development of antiaging and anticancer therapeutics. PMID:26503788

A satellite observational and numerical study of precipitation characteristics in western North Atlantic tropical cyclones

NASA Technical Reports Server (NTRS)

Rodgers, Edward B.; Chang, Simon W.; Pierce, Harold F.

1994-01-01

Special Sensor Microwave/Imager (SSM/I) observations were used to examine the spatial and temporal changes of the precipitation characteristics of tropical cyclones. SSM/I observations were also combined with the results of a tropical cyclone numerical model to examine the role of inner-core diabatic heating in subsequent intensity changes of tropical cyclones. Included in the SSM/I observations were rainfall characteristics of 18 named western North Atlantic tropical cyclones between 1987 and 1989. The SSM/I rain-rate algorithm that employed the 85-GHz channel provided an analysis of the rain-rate distribution in greater detail. However, the SSM/I algorithm underestimated the rain rates when compared to in situ techniques but appeared to be comparable to the rain rates obtained from other satellite-borne passive microwave radiometers. The analysis of SSM/I observations found that more intense systems had higher rain rates, more latent heat release, and a greater contribution from heavier rain to the total tropical cyclone rainfall. In addition, regions with the heaviest rain rates were found near the center of the most intense tropical cyclones. Observational analysis from SSM/I also revealed that the greatest rain rates in the inner-core regions were found in the right half of fast-moving cyclones, while the heaviest rain rates in slow-moving tropical cyclones were found in the forward half. The combination of SSM/I observations and an interpretation of numerical model simulations revealed that the correlation between changes in the inner core diabetic heating and the subsequent intensity became greater as the tropical cyclones became more intense.

Treatment and postrelease rehabilitative programs for juvenile offenders.

PubMed

Underwood, Lee A; Knight, Pamela

2006-04-01

The juvenile justice system has become notably aware of the increasing use of postrelease rehabilitative treatment interventions for offenders. In many instances, juvenile justice systems are required to ensure that core treatment needs of youth are met. As a result of the heightened awareness of the need for postrelease rehabilitation treatment programs, many researchers and providers are calling for more systematic approaches to offender treatment. This article summarizes a body of literature on juvenile offenders who have specialized postrelease rehabilitative treatment needs. It reviews cognitive-behavioral theoretical models and core postrelease treatment strategies. It presents a review of youth who have specialized needs in light of postrelease practices, describes several model postrelease rehabilitation programs, and reviews outcomes of these programs.

Integrating the older/special needs adoptive child into the family.

PubMed

Clark, Pamela; Thigpen, Sally; Yates, Amy Moeller

2006-04-01

This qualitative, grounded theory study investigated 11 families who reported having successfully integrated into their family unit at least one older/special needs adoptee. The theory that emerged through the constant comparative methodology consisted of two categories (Decision to Adopt and Adjustment) and a core category (Developing a Sense of Family). The two categories and core category comprised a process that was informed by the Family Narrative Paradigm and culminated in the successful integration of the child or children into the existing family unit. Parental perceptions that appeared to facilitate this process included: (a) finding strengths in the children overlooked by previous caregivers, (b) viewing behavior in context, (c) reframing negative behavior, and (d) attributing improvement in behavior to parenting efforts.

In-core flux sensor evaluations at the ATR critical facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Troy Unruh; Benjamin Chase; Joy Rempe

2014-09-01

Flux detector evaluations were completed as part of a joint Idaho State University (ISU) / Idaho National Laboratory (INL) / French Atomic Energy commission (CEA) ATR National Scientific User Facility (ATR NSUF) project to compare the accuracy, response time, and long duration performance of several flux detectors. Special fixturing developed by INL allows real-time flux detectors to be inserted into various ATRC core positions and perform lobe power measurements, axial flux profile measurements, and detector cross-calibrations. Detectors initially evaluated in this program include the French Atomic Energy Commission (CEA)-developed miniature fission chambers; specialized self-powered neutron detectors (SPNDs) developed by themore » Argentinean National Energy Commission (CNEA); specially developed commercial SPNDs from Argonne National Laboratory. As shown in this article, data obtained from this program provides important insights related to flux detector accuracy and resolution for subsequent ATR and CEA experiments and flux data required for bench-marking models in the ATR V&V Upgrade Initiative.« less

Fabrication and Testing of a Modular Micro-Pocket Fission Detector Instrumentation System for Test Nuclear Reactors

NASA Astrophysics Data System (ADS)

Reichenberger, Michael A.; Nichols, Daniel M.; Stevenson, Sarah R.; Swope, Tanner M.; Hilger, Caden W.; Roberts, Jeremy A.; Unruh, Troy C.; McGregor, Douglas S.

2018-01-01

Advancements in nuclear reactor core modeling and computational capability have encouraged further development of in-core neutron sensors. Measurement of the neutron-flux distribution within the reactor core provides a more complete understanding of the operating conditions in the reactor than typical ex-core sensors. Micro-Pocket Fission Detectors have been developed and tested previously but have been limited to single-node operation and have utilized highly specialized designs. The development of a widely deployable, multi-node Micro-Pocket Fission Detector assembly will enhance nuclear research capabilities. A modular, four-node Micro-Pocket Fission Detector array was designed, fabricated, and tested at Kansas State University. The array was constructed from materials that do not significantly perturb the neutron flux in the reactor core. All four sensor nodes were equally spaced axially in the array to span the fuel-region of the reactor core. The array was filled with neon gas, serving as an ionization medium in the small cavities of the Micro-Pocket Fission Detectors. The modular design of the instrument facilitates the testing and deployment of numerous sensor arrays. The unified design drastically improved device ruggedness and simplified construction from previous designs. Five 8-mm penetrations in the upper grid plate of the Kansas State University TRIGA Mk. II research nuclear reactor were utilized to deploy the array between fuel elements in the core. The Micro-Pocket Fission Detector array was coupled to an electronic support system which has been specially developed to support pulse-mode operation. The Micro-Pocket Fission Detector array composed of four sensors was used to monitor local neutron flux at a constant reactor power of 100 kWth at different axial locations simultaneously. The array was positioned at five different radial locations within the core to emulate the deployment of multiple arrays and develop a 2-dimensional measurement of neutron flux in the reactor core.

The Role of Leadership in Changing the Culture of an International School to Be Inclusive of Students with Special Learning Needs

ERIC Educational Resources Information Center

Gillespie, Simon

2017-01-01

Educating a diverse student population is a core principle of international school education. Historically, many international schools have had admissions policies that excluded students with special learning needs. However, admission policies have changed to require more inclusiveness and school support for a wider range of students and for…

High Stakes Testing in the 21st Century: Implications for Students in Special Education

ERIC Educational Resources Information Center

Gordon, Lola

2016-01-01

High-stakes testing has been a part of American education since its inception. The laws that govern the use of high-stakes tests include language that mandates the inclusion of students in special education. These laws play an influential role in the new large-scale assessments aligned with the Common Core State Standards (CCSS). The assessments…

Instructional Supports for Students with Special Education Needs in French as a Second Language Education: A Review of Canadian Empirical Literature

ERIC Educational Resources Information Center

Mady, Callie; Muhling, Stefanie

2017-01-01

With the view to responding to a call for information on instructional supports for students with special education needs (SSEN) in French as a second language (FSL) education, this article reviews the empirical literature from three Canadian contexts: core French, intensive French and French immersion. More specifically, we developed this…

Protocol for the Assessment of Common Core Teaching: The Impact of Instructional Inclusion on Students with Special Needs

ERIC Educational Resources Information Center

Gallagher, Kathleen L.; Odozi, Anthony

2015-01-01

The quality of instruction in the classroom is the most powerful leverage point for school improvement because it is the only thing over which educators have a significant degree of control. As student assessments change to reflect the higher expectations of Common Core State Standards (CCSS), it is important that the assessment and development of…

The Utilization of the Microflora Indigenous to and Present in Oil-Bearing Formations to Selectively Plug the More Porous Zones Thereby Increasing Oil Recovery During Waterflooding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Lewis R.; Stephens, James O.; Vadie, Alex A.

The objective of this work is to demonstrate the use of indigenous microbes as a method of profile control in waterfloods. It is expected that as the microbial population is induced to increase, that the expanded biomass will selectively block the more permeable zones of the reservoir thereby forcing injection water to flow through the less permeable zones which will result in improved sweep efficiency. This increase in microbial population will be accomplished by injecting a nutrient solution into four injectors. Four other injectors will act as control wells. During Phase I, two wells will be cored through the zonemore » of interest. The core will be subjected to special core analyses in order to arrive at the optimum nutrient formulation. During Phase II, nutrient injection will begin, the results monitored, and adjustments to the nutrient composition made, if necessary. Phase II also will include the drilling of three wells for post-mortem core analysis. Phase III will focus on technology transfer of the results. It should be pointed out that one expected outcome of this new technology will be a prolongation of economical waterflooding operations, i.e. economical oil recovery should continue for much longer periods in the producing wells subjected to this selective plugging technique.« less

Dynamical Core in Atmospheric Model Does Matter in the Simulation of Arctic Climate

NASA Astrophysics Data System (ADS)

Jun, Sang-Yoon; Choi, Suk-Jin; Kim, Baek-Min

2018-03-01

Climate models using different dynamical cores can simulate significantly different winter Arctic climates even if equipped with virtually the same physics schemes. Current climate simulated by the global climate model using cubed-sphere grid with spectral element method (SE core) exhibited significantly warmer Arctic surface air temperature compared to that using latitude-longitude grid with finite volume method core. Compared to the finite volume method core, SE core simulated additional adiabatic warming in the Arctic lower atmosphere, and this was consistent with the eddy-forced secondary circulation. Downward longwave radiation further enhanced Arctic near-surface warming with a higher surface air temperature of about 1.9 K. Furthermore, in the atmospheric response to the reduced sea ice conditions with the same physical settings, only the SE core showed a robust cooling response over North America. We emphasize that special attention is needed in selecting the dynamical core of climate models in the simulation of the Arctic climate and associated teleconnection patterns.

Fast multi-core based multimodal registration of 2D cross-sections and 3D datasets

PubMed Central

2010-01-01

Background Solving bioinformatics tasks often requires extensive computational power. Recent trends in processor architecture combine multiple cores into a single chip to improve overall performance. The Cell Broadband Engine (CBE), a heterogeneous multi-core processor, provides power-efficient and cost-effective high-performance computing. One application area is image analysis and visualisation, in particular registration of 2D cross-sections into 3D image datasets. Such techniques can be used to put different image modalities into spatial correspondence, for example, 2D images of histological cuts into morphological 3D frameworks. Results We evaluate the CBE-driven PlayStation 3 as a high performance, cost-effective computing platform by adapting a multimodal alignment procedure to several characteristic hardware properties. The optimisations are based on partitioning, vectorisation, branch reducing and loop unrolling techniques with special attention to 32-bit multiplies and limited local storage on the computing units. We show how a typical image analysis and visualisation problem, the multimodal registration of 2D cross-sections and 3D datasets, benefits from the multi-core based implementation of the alignment algorithm. We discuss several CBE-based optimisation methods and compare our results to standard solutions. More information and the source code are available from http://cbe.ipk-gatersleben.de. Conclusions The results demonstrate that the CBE processor in a PlayStation 3 accelerates computational intensive multimodal registration, which is of great importance in biological/medical image processing. The PlayStation 3 as a low cost CBE-based platform offers an efficient option to conventional hardware to solve computational problems in image processing and bioinformatics. PMID:20064262

Deterministic Modeling of the High Temperature Test Reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ortensi, J.; Cogliati, J. J.; Pope, M. A.

2010-06-01

Idaho National Laboratory (INL) is tasked with the development of reactor physics analysis capability of the Next Generation Nuclear Power (NGNP) project. In order to examine INL’s current prismatic reactor deterministic analysis tools, the project is conducting a benchmark exercise based on modeling the High Temperature Test Reactor (HTTR). This exercise entails the development of a model for the initial criticality, a 19 column thin annular core, and the fully loaded core critical condition with 30 columns. Special emphasis is devoted to the annular core modeling, which shares more characteristics with the NGNP base design. The DRAGON code is usedmore » in this study because it offers significant ease and versatility in modeling prismatic designs. Despite some geometric limitations, the code performs quite well compared to other lattice physics codes. DRAGON can generate transport solutions via collision probability (CP), method of characteristics (MOC), and discrete ordinates (Sn). A fine group cross section library based on the SHEM 281 energy structure is used in the DRAGON calculations. HEXPEDITE is the hexagonal z full core solver used in this study and is based on the Green’s Function solution of the transverse integrated equations. In addition, two Monte Carlo (MC) based codes, MCNP5 and PSG2/SERPENT, provide benchmarking capability for the DRAGON and the nodal diffusion solver codes. The results from this study show a consistent bias of 2–3% for the core multiplication factor. This systematic error has also been observed in other HTTR benchmark efforts and is well documented in the literature. The ENDF/B VII graphite and U235 cross sections appear to be the main source of the error. The isothermal temperature coefficients calculated with the fully loaded core configuration agree well with other benchmark participants but are 40% higher than the experimental values. This discrepancy with the measurement stems from the fact that during the experiments the control rods were adjusted to maintain criticality, whereas in the model, the rod positions were fixed. In addition, this work includes a brief study of a cross section generation approach that seeks to decouple the domain in order to account for neighbor effects. This spectral interpenetration is a dominant effect in annular HTR physics. This analysis methodology should be further explored in order to reduce the error that is systematically propagated in the traditional generation of cross sections.« less

Multicore fiber beamforming network for broadband satellite communications

NASA Astrophysics Data System (ADS)

Zainullin, Airat; Vidal, Borja; Macho, Andres; Llorente, Roberto

2017-02-01

Multi-core fiber (MCF) has been one of the main innovations in fiber optics in the last decade. Reported work on MCF has been focused on increasing the transmission capacity of optical communication links by exploiting space-division multiplexing. Additionally, MCF presents a strong potential in optical beamforming networks. The use of MCF can increase the compactness of the broadband antenna array controller. This is of utmost importance in platforms where size and weight are critical parameters such as communications satellites and airplanes. Here, an optical beamforming architecture that exploits the space-division capacity of MCF to implement compact optical beamforming networks is proposed, being a new application field for MCF. The experimental demonstration of this system using a 4-core MCF that controls a four-element antenna array is reported. An analysis of the impact of MCF on the performance of antenna arrays is presented. The analysis indicates that the main limitation comes from the relatively high insertion loss in the MCF fan-in and fan-out devices, which leads to angle dependent losses which can be mitigated by using fixed optical attenuators or a photonic lantern to reduce MCF insertion loss. The crosstalk requirements are also experimentally evaluated for the proposed MCF-based architecture. The potential signal impairment in the beamforming network is analytically evaluated, being of special importance when MCF with a large number of cores is considered. Finally, the optimization of the proposed MCF-based beamforming network is addressed targeting the scalability to large arrays.

System for Automated Geoscientific Analyses (SAGA) v. 2.1.4

NASA Astrophysics Data System (ADS)

Conrad, O.; Bechtel, B.; Bock, M.; Dietrich, H.; Fischer, E.; Gerlitz, L.; Wehberg, J.; Wichmann, V.; Böhner, J.

2015-02-01

The System for Automated Geoscientific Analyses (SAGA) is an open-source Geographic Information System (GIS), mainly licensed under the GNU General Public License. Since its first release in 2004, SAGA has rapidly developed from a specialized tool for digital terrain analysis to a comprehensive and globally established GIS platform for scientific analysis and modeling. SAGA is coded in C++ in an object oriented design and runs under several operating systems including Windows and Linux. Key functional features of the modular organized software architecture comprise an application programming interface for the development and implementation of new geoscientific methods, an easily approachable graphical user interface with many visualization options, a command line interpreter, and interfaces to scripting and low level programming languages like R and Python. The current version 2.1.4 offers more than 700 tools, which are implemented in dynamically loadable libraries or shared objects and represent the broad scopes of SAGA in numerous fields of geoscientific endeavor and beyond. In this paper, we inform about the system's architecture, functionality, and its current state of development and implementation. Further, we highlight the wide spectrum of scientific applications of SAGA in a review of published studies with special emphasis on the core application areas digital terrain analysis, geomorphology, soil science, climatology and meteorology, as well as remote sensing.

System for Automated Geoscientific Analyses (SAGA) v. 2.1.4

NASA Astrophysics Data System (ADS)

Conrad, O.; Bechtel, B.; Bock, M.; Dietrich, H.; Fischer, E.; Gerlitz, L.; Wehberg, J.; Wichmann, V.; Böhner, J.

2015-07-01

The System for Automated Geoscientific Analyses (SAGA) is an open source geographic information system (GIS), mainly licensed under the GNU General Public License. Since its first release in 2004, SAGA has rapidly developed from a specialized tool for digital terrain analysis to a comprehensive and globally established GIS platform for scientific analysis and modeling. SAGA is coded in C++ in an object oriented design and runs under several operating systems including Windows and Linux. Key functional features of the modular software architecture comprise an application programming interface for the development and implementation of new geoscientific methods, a user friendly graphical user interface with many visualization options, a command line interpreter, and interfaces to interpreted languages like R and Python. The current version 2.1.4 offers more than 600 tools, which are implemented in dynamically loadable libraries or shared objects and represent the broad scopes of SAGA in numerous fields of geoscientific endeavor and beyond. In this paper, we inform about the system's architecture, functionality, and its current state of development and implementation. Furthermore, we highlight the wide spectrum of scientific applications of SAGA in a review of published studies, with special emphasis on the core application areas digital terrain analysis, geomorphology, soil science, climatology and meteorology, as well as remote sensing.

IDEA at Age Forty: Weathering Common Core Standards and Data Driven Decision Making

ERIC Educational Resources Information Center

Bicehouse, Vaughn; Faieta, Jean

2017-01-01

Special education, a discipline that aims to provide specialized instruction to meet the unique needs of each child with a disability, has turned 40 years old in the United States. Ever since the passage of the Education for All Handicapped Children Act (P.L. 94-142) in 1975, every state has been directed to provide a free and appropriate…

Neurodiversity in the Classroom: Strength-Based Strategies to Help Students with Special Needs Succeed in School and Life

ERIC Educational Resources Information Center

Armstrong, Thomas

2012-01-01

By looking at the positive strengths of your students with special needs, you can help those students flourish, ensure their success, and align their instruction to Common Core State Standards. One of our most popular authors, Thomas Armstrong, shows you the steps you need to take to establish a more favorable, productive learning environment for…

The Transition from the Core Vowels to the Following Segments in Japanese Children Who Stutter: The Second, Third and Fourth Syllables

ERIC Educational Resources Information Center

Matsumoto-Shimamori, Sachiyo; Ito, Tomohiko; Fukuda, Suzy E.; Fukuda, Shinji

2011-01-01

Shimamori and Ito (2007, Syllable weight and phonological encoding in Japanese children who stutter. "Japanese Journal of Special Education", 44, 451-462; 2008, Syllable weight and frequency of stuttering: Comparison between children who stutter with and without a family history of stuttering. "Japanese Journal of Special Education", 45, 437-445;…

Black Economic Advancement in the New Millennium: Globalization, Education, and Technology. Special Report: National Policy Institute (8th, Washington, DC, January 20-22, 2000).

ERIC Educational Resources Information Center

Focus, 2000

2000-01-01

This special issue presents, in capsule form, presentations from workshops at the Eighth National Policy Institute. The conference theme of black economic advancement in the new century focused on globalization, education, and technology. Ten workshops were the core of the conference, and their topics were: (1) overcoming the 2000 Census…

Illuminating system and method for specialized and decorative lighting using liquid light guides

DOEpatents

Zorn, C.J.; Kross, B.J.; Majewski, S.; Wojcik, R.F.

1998-08-25

The present invention comprises an illumination system for specialized decorative lighting including a light source, a flexible plastic tube sheath for distributing the light to a remote location, a transparent liquid core filling the tube that has an index of refraction greater than that of the plastic tube and an arrangement where light coupled from the light source is caused to leak from the liquid light guide at desired locations for the purposes of specialized lighting, such as underwater illumination in swimming pools. 5 figs.

Illuminating system and method for specialized and decorative lighting using liquid light guides

DOEpatents

Zorn, Carl J.; Kross, Brian J.; Majewski, Stanislaw; Wojcik, Randolph F.

1998-01-01

The present invention comprises an illumination system for specialized decorative lighting including a light source, a flexible plastic tube sheath for distributing the light to a remote location, a transparent liquid core filling the tube that has an index of refraction greater than that of the plastic tube and an arrangement where light coupled from the light source is caused to leak from the liquid light guide at desired locations for the purposes of specialized lighting, such as underwater illumination in swimming pools.

Positioning Mechanism For Hoisting

NASA Technical Reports Server (NTRS)

Marlin, John D., III; Moore, Barry J.; Myers, Robert I.

1992-01-01

Mechanism positions large, heavy objects in container for lifting out by hoist, crane, or winch. Handles objects gently and ensures they are lifted cleanly away in vertical direction without bumping container. Developed for lifting offset pieces of solid-propellant core out of rocket motor through its propellant port. Similar specialized mechanisms can be developed to lift other specially shaped, specially contained heavy objects. Track in base of mechanism guides each trunnion and piece to which attached to middle as hydraulic rods extend. When mechanism lifted, tilted pieces swing inward and come to rest on energy-absorbing paddle.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huml, O.

The objective of this work was to determine the neutron flux density distribution in various places of the training reactor VR-1 Sparrow. This experiment was performed on the new core design C1, composed of the new low-enriched uranium fuel cells IRT-4M (19.7 %). This fuel replaced the old high-enriched uranium fuel IRT-3M (36 %) within the framework of the RERTR Program in September 2005. The measurement used the neutron activation analysis method with gold wires. The principle of this method consists in neutron capture in a nucleus of the material forming the activation detector. This capture can change the nucleusmore » in a radioisotope, whose activity can be measured. The absorption cross-section values were evaluated by MCNP computer code. The gold wires were irradiated in seven different positions in the core C1. All irradiations were performed at reactor power level 1E8 (1 kW{sub therm}). The activity of segments of irradiated wires was measured by special automatic device called 'Drat' (Wire in English). (author)« less

Evaluation of a uranium zirconium hydride fuel rod option for conversion of the MIT research reactor (MITR) from highly-enriched uranium to low-enriched uranium

DOE PAGES

Dunn, F. E.; Wilson, E. H.; Feldman, E. E.; ...

2017-03-23

The conversion of the Massachusetts Institute of Technology Reactor (MITR) from the use of highly-enriched uranium (HEU) fuel-plate assemblies to low-enriched uranium (LEU) by replacing the HEU fuel plates with specially designed General Atomics (GA) uranium zirconium hydride (UZrH) LEU fuel rods is evaluated in this paper. The margin to critical heat flux (CHF) in the core, which is cooled by light water at low pressure, is evaluated analytically for steady-state operation. A form of the Groeneveld CHF lookup table method is used and described in detail. A CHF ratio of 1.41 was found in the present analysis at 10more » MW with engineering hot channel factors included. Therefore, the nominal reactor core power, and neutron flux performance, would need to be reduced by at least 25% in order to meet the regulatory requirement of a minimum CHF ratio of 2.0.« less

Evaluation of a uranium zirconium hydride fuel rod option for conversion of the MIT research reactor (MITR) from highly-enriched uranium to low-enriched uranium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunn, F. E.; Wilson, E. H.; Feldman, E. E.

The conversion of the Massachusetts Institute of Technology Reactor (MITR) from the use of highly-enriched uranium (HEU) fuel-plate assemblies to low-enriched uranium (LEU) by replacing the HEU fuel plates with specially designed General Atomics (GA) uranium zirconium hydride (UZrH) LEU fuel rods is evaluated in this paper. The margin to critical heat flux (CHF) in the core, which is cooled by light water at low pressure, is evaluated analytically for steady-state operation. A form of the Groeneveld CHF lookup table method is used and described in detail. A CHF ratio of 1.41 was found in the present analysis at 10more » MW with engineering hot channel factors included. Therefore, the nominal reactor core power, and neutron flux performance, would need to be reduced by at least 25% in order to meet the regulatory requirement of a minimum CHF ratio of 2.0.« less

Statistics of gravitational lenses - The uncertainties

NASA Technical Reports Server (NTRS)

Mao, Shude

1991-01-01

The assumptions in the analysis of gravitational lensing statistics are examined. Special emphasis is given to the uncertainties in the theoretical predictions. It is shown that a simple redshift cutoff model, which may result from galaxy evolution, can significantly reduce the lensing probability and explain the large mean separation of images in observed gravitational lenses. This effect may affect the constraint on the contribution of the cosmological constant to producing a flat universe from the number counts of the observed lenses. For the Omega(0) = 1 (filled beam) model, the lensing probability of early-type galaxies with finite core radii is reduced roughly by a factor of 2 for high-redshift quasars as compared with the corresponding singular isothermal sphere model. The finite core radius effect is about 20 percent for a lambda-dominated flat universe. It is also shown that the most recent galaxy luminosity function gives lensing probabilities that are smaller than previously estimated roughly by a factor of 3.

78 FR 76328 - Application for Renewal of Special Nuclear Material License SNM-2014 From Tennessee Valley...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-17

... SNM in the form of fully-assembled fuel assemblies that would later form the initial reactor core of WBN2. The SNM in the fuel assemblies is enriched up to 5% in the isotope U-235. The fresh fuel... received the initial core for WBN2. The NRC has not yet issued the OL for the Unit 2 reactor. The...

Finding the Common Ground: A Comparison of Writing Expectations and Outcomes between the Texas Essential Knowledge and Skills and the Common Core State Standards

ERIC Educational Resources Information Center

Jacoby, Pat; Vasinda, Sheri

2014-01-01

In the Winter 2013 edition of the "Texas Journal of Literacy Education," we announced that a special task force from the TALE board would be sharing the common ground among the Texas Essential Knowledge and Skills (TEKS), Common Core State Standards (CCSS), and the College and Career Readiness Standards (CCRS). In that first edition, we…

An innovative piston corer for large‐volume sediment samples

PubMed Central

Haselmair, Alexandra; Stachowitsch, Michael; Zuschin, Martin

2016-01-01

Abstract Coring is one of several standard procedures to extract sediments and their faunas from open marine, estuarine, and limnic environments. Achieving sufficiently deep penetration, obtaining large sediment volumes in single deployments, and avoiding sediment loss upon retrieval remain problematic. We developed a piston corer with a diameter of 16 cm that enables penetration down to 1.5 m in a broad range of soft bottom types, yields sufficient material for multiple analyses, and prevents sediment loss due to a specially designed hydraulic core catcher. A novel extrusion system enables very precise slicing and preserves the original sediment stratification by keeping the liners upright. The corer has moderate purchase costs and a robust and simple design that allows for a deployment from relatively small vessels as available at most marine science institutions. It can easily be operated by two to three researchers rather than by specially trained technicians. In the northern Adriatic Sea, the corer successfully extracted more than 50 cores from a range of fine mud to coarse sand, at water depths from three to 45 m. The initial evaluation of the cores demonstrated their usefulness for fauna sequences along with heavy metal, nutrient and pollutant analyses. Their length is particularly suited for historical ecological work requiring sedimentary and faunal sequences to reconstruct benthic communities over the last millennia. PMID:28111529

Few Ant Species Play a Central Role Linking Different Plant Resources in a Network in Rupestrian Grasslands

PubMed Central

Mello, Marco A. R.; Bronstein, Judith L.; Guerra, Tadeu J.; Muylaert, Renata L.; Leite, Alice C.; Neves, Frederico S.

2016-01-01

Ant-plant associations are an outstanding model to study the entangled ecological interactions that structure communities. However, most studies of plant-animal networks focus on only one type of resource that mediates these interactions (e.g, nectar or fruits), leading to a biased understanding of community structure. New approaches, however, have made possible to study several interaction types simultaneously through multilayer networks models. Here, we use this approach to ask whether the structural patterns described to date for ant-plant networks hold when multiple interactions with plant-derived food rewards are considered. We tested whether networks characterized by different resource types differ in specialization and resource partitioning among ants, and whether the identity of the core ant species is similar among resource types. We monitored ant interactions with extrafloral nectaries, flowers, and fruits, as well as trophobiont hemipterans feeding on plants, for one year, in seven rupestrian grassland (campo rupestre) sites in southeastern Brazil. We found a highly tangled ant-plant network in which plants offering different resource types are connected by a few central ant species. The multilayer network had low modularity and specialization, but ant specialization and niche overlap differed according to the type of resource used. Beyond detecting structural differences across networks, our study demonstrates empirically that the core of most central ant species is similar across them. We suggest that foraging strategies of ant species, such as massive recruitment, may determine specialization and resource partitioning in ant-plant interactions. As this core of ant species is involved in multiple ecosystem functions, it may drive the diversity and evolution of the entire campo rupestre community. PMID:27911919

High quality tissue miniarray technique using a conventional TV/radio telescopic antenna.

PubMed

Elkablawy, Mohamed A; Albasri, Abdulkader M

2015-01-01

The tissue microarray (TMA) is widely accepted as a fast and cost-effective research tool for in situ tissue analysis in modern pathology. However, the current automated and manual TMA techniques have some drawbacks restricting their productivity. Our study aimed to introduce an improved manual tissue miniarray (TmA) technique that is simple and readily applicable to a broad range of tissue samples. In this study, a conventional TV/radio telescopic antenna was used to punch tissue cores manually from donor paraffin embedded tissue blocks which were pre-incubated at 40oC. The cores were manually transferred, organized and attached to a standard block mould, and filled with liquid paraffin to construct TmA blocks without any use of recipient paraffin blocks. By using a conventional TV/radio antenna, it was possible to construct TmA paraffin blocks with variable formats of array size and number (2-mm x 42, 2.5-mm x 30, 3-mm x 24, 4-mm x 20 and 5-mm x 12 cores). Up to 2-mm x 84 cores could be mounted and stained on a standard microscopic slide by cutting two sections from two different blocks and mounting them beside each other. The technique was simple and caused minimal damage to the donor blocks. H and E and immunostained slides showed well-defined tissue morphology and array configuration. This technique is easy to reproduce, quick, inexpensive and creates uniform blocks with abundant tissues without specialized equipment. It was found to improve the stability of the cores within the paraffin block and facilitated no losses during cutting and immunostaining.

[Soldiers and HIV: impact of medical knowledge on the analysis of discrimination in the constitution].

PubMed

Pou Giménez, Francisca

2012-01-01

In 2007 the Mexican Supreme Court issued several opinions dealing with military personnel dismissed from the Army because of their being HIV-positive. The author describes the main questions under discussion and the core arguments developed by the Court, and stresses three reasons why these cases deserve close attention: positively, because they reinforced the use of the proportionality principle as a tool for identifying discriminatory norms and because they opened the door to the use of specialized scientific knowledge in constitutional adjudication; negatively, because they failed to build on the direct normative efficacy of the right to health.

40 CFR 467.31 - Specialized definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... definitions. For the purpose of this subpart: (a) The “core” of the extrusion subcategory shall include... the core, performed on-site, following or preceding the extrusion operation. The ancillary operations...

40 CFR 467.31 - Specialized definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... definitions. For the purpose of this subpart: (a) The “core” of the extrusion subcategory shall include... the core, performed on-site, following or preceding the extrusion operation. The ancillary operations...

A fast CT reconstruction scheme for a general multi-core PC.

PubMed

Zeng, Kai; Bai, Erwei; Wang, Ge

2007-01-01

Expensive computational cost is a severe limitation in CT reconstruction for clinical applications that need real-time feedback. A primary example is bolus-chasing computed tomography (CT) angiography (BCA) that we have been developing for the past several years. To accelerate the reconstruction process using the filtered backprojection (FBP) method, specialized hardware or graphics cards can be used. However, specialized hardware is expensive and not flexible. The graphics processing unit (GPU) in a current graphic card can only reconstruct images in a reduced precision and is not easy to program. In this paper, an acceleration scheme is proposed based on a multi-core PC. In the proposed scheme, several techniques are integrated, including utilization of geometric symmetry, optimization of data structures, single-instruction multiple-data (SIMD) processing, multithreaded computation, and an Intel C++ compilier. Our scheme maintains the original precision and involves no data exchange between the GPU and CPU. The merits of our scheme are demonstrated in numerical experiments against the traditional implementation. Our scheme achieves a speedup of about 40, which can be further improved by several folds using the latest quad-core processors.

Report from the OMERACT Hand Osteoarthritis Special Interest Group: advances and future research priorities.

PubMed

Kloppenburg, Margreet; Bøyesen, Pernille; Smeets, Wilma; Haugen, Ida K; Haugen, Ida; Liu, Rani; Visser, Willemien; van der Heijde, Désirée M

2014-04-01

Osteoarthritis (OA) is one of the most common musculoskeletal disorders, frequently affecting the hands. In the last decade there has been increased awareness concerning this disorder because of its clinical burden. Unfortunately, only limited treatments for symptom alleviation are available, and no effective treatment for disease modification exists. The lack of treatment is due not only to a lack of understanding of the disease process, but also to poor outcome measures to assess the condition. The OMERACT Hand OA Special Interest Group (SIG) has started to develop a core set of outcome measures for hand OA clinical trials, observational studies, and clinical record keeping. At OMERACT 11, results from a Delphi exercise were presented, and a preliminary set of core domains was discussed. The group attempted to adopt the new OMERACT Filter 2.0 in the process, and literature overviews of conventional radiographs, ultrasonography, and magnetic resonance imaging as outcome measures in hand OA were presented. Discussions that followed highlighted further suggestions for core domains, the heterogeneity of hand OA, and future research priorities.

A Fast CT Reconstruction Scheme for a General Multi-Core PC

PubMed Central

Zeng, Kai; Bai, Erwei; Wang, Ge

2007-01-01

Expensive computational cost is a severe limitation in CT reconstruction for clinical applications that need real-time feedback. A primary example is bolus-chasing computed tomography (CT) angiography (BCA) that we have been developing for the past several years. To accelerate the reconstruction process using the filtered backprojection (FBP) method, specialized hardware or graphics cards can be used. However, specialized hardware is expensive and not flexible. The graphics processing unit (GPU) in a current graphic card can only reconstruct images in a reduced precision and is not easy to program. In this paper, an acceleration scheme is proposed based on a multi-core PC. In the proposed scheme, several techniques are integrated, including utilization of geometric symmetry, optimization of data structures, single-instruction multiple-data (SIMD) processing, multithreaded computation, and an Intel C++ compilier. Our scheme maintains the original precision and involves no data exchange between the GPU and CPU. The merits of our scheme are demonstrated in numerical experiments against the traditional implementation. Our scheme achieves a speedup of about 40, which can be further improved by several folds using the latest quad-core processors. PMID:18256731

A single-cell analysis platform for electrochemiluminescent detection of platelets adhesion to endothelial cells based on Au@DL-ZnCQDs nanoprobes.

PubMed

Long, Dongping; Shang, Yunfei; Qiu, Youyi; Zhou, Bin; Yang, Peihui

2018-04-15

A novel single-cell analysis platform (SCA) was developed for the investigation of platelets adhesion to single human umbilical vein endothelial cell (HUVEC) via using the adhesion molecule (E-selectin) on the damaged HUVEC as the marker site, and integrating electrochemiluminescence (ECL) with the ultrasensitive Au@DL-ZnCQDs nanoprobes. The Au@DL-ZnCQDs nanocomposite, a kind of double layer zinc-coadsorbed carbon quantum dot (ZnCQDs) core-shell nanoprobe, was firstly constructed by using gold nanoparticles (AuNPs) as the core to load with ZnCQDs and then the citrate-modified silver nanoparticles (AgNPs) as the bridge to link AuNPs-ZnCQDs with ZnCQDs to form the core-shell with double layer ZnCQDs (DL-ZnCQDs) nanoprobe, revealed a 10-fold signal amplification. The H 2 O 2 -induced oxidative damage HUVECs were utilized as the cellular model on which anti-E-selectin functionalized nanoprobes specially recognized E-selectin, the SCA showed that the ECL signals decreased with platelets adhesion to single HUVEC. The proposed SCA could effectively and dynamically monitor the adhesion between single HUVEC and platelets in the absence and presence of collagen activation, moreover, be able to quantitatively detect the number of platelets adhesion to single HUVEC, and show a good analytical performance with linear range from 1 to 15 platelets. In contrast, the HUVEC was down-regulated the expression of adhesion molecules by treating with quercetin inhibitor, and the SCA also exhibited the feasibility for analysis of platelets adhesion to single HUVEC. Therefore, the single-cell analysis platform provided a novel and promising protocol for analysis of the single intercellular adhesion, and it will be beneficial to elucidate the pathogenesis of cardiovascular diseases. Copyright © 2017 Elsevier B.V. All rights reserved.

Design and implementation of spatial knowledge grid for integrated spatial analysis

NASA Astrophysics Data System (ADS)

Liu, Xiangnan; Guan, Li; Wang, Ping

2006-10-01

Supported by spatial information grid(SIG), the spatial knowledge grid (SKG) for integrated spatial analysis utilizes the middleware technology in constructing the spatial information grid computation environment and spatial information service system, develops spatial entity oriented spatial data organization technology, carries out the profound computation of the spatial structure and spatial process pattern on the basis of Grid GIS infrastructure, spatial data grid and spatial information grid (specialized definition). At the same time, it realizes the complex spatial pattern expression and the spatial function process simulation by taking the spatial intelligent agent as the core to establish space initiative computation. Moreover through the establishment of virtual geographical environment with man-machine interactivity and blending, complex spatial modeling, network cooperation work and spatial community decision knowledge driven are achieved. The framework of SKG is discussed systematically in this paper. Its implement flow and the key technology with examples of overlay analysis are proposed as well.

Using a Four-Point Scaled Writing Rubric: Improving the Quantity and the Quality of the Writing in a First Grade Specialized 8:1:1 Classroom

ERIC Educational Resources Information Center

Carlson, Lynn

2013-01-01

Educators today are faced with learning to implement the Common Core Standards in Language Arts and Math. Administrators are requiring grade level general education teachers/special education teachers to meet in Private Learning Communities in order to discuss the best ways to implement the CCS as well as to discuss best practices for writing…

Evolutionary routes to biochemical innovation revealed by integrative analysis of a plant-defense related specialized metabolic pathway

PubMed Central

Moghe, Gaurav D; Leong, Bryan J; Hurney, Steven M; Daniel Jones, A

2017-01-01

The diversity of life on Earth is a result of continual innovations in molecular networks influencing morphology and physiology. Plant specialized metabolism produces hundreds of thousands of compounds, offering striking examples of these innovations. To understand how this novelty is generated, we investigated the evolution of the Solanaceae family-specific, trichome-localized acylsugar biosynthetic pathway using a combination of mass spectrometry, RNA-seq, enzyme assays, RNAi and phylogenomics in different non-model species. Our results reveal hundreds of acylsugars produced across the Solanaceae family and even within a single plant, built on simple sugar cores. The relatively short biosynthetic pathway experienced repeated cycles of innovation over the last 100 million years that include gene duplication and divergence, gene loss, evolution of substrate preference and promiscuity. This study provides mechanistic insights into the emergence of plant chemical novelty, and offers a template for investigating the ~300,000 non-model plant species that remain underexplored. PMID:28853706

Evolutionary routes to biochemical innovation revealed by integrative analysis of a plant-defense related specialized metabolic pathway.

PubMed

Moghe, Gaurav D; Leong, Bryan J; Hurney, Steven M; Daniel Jones, A; Last, Robert L

2017-08-30

The diversity of life on Earth is a result of continual innovations in molecular networks influencing morphology and physiology. Plant specialized metabolism produces hundreds of thousands of compounds, offering striking examples of these innovations. To understand how this novelty is generated, we investigated the evolution of the Solanaceae family-specific, trichome-localized acylsugar biosynthetic pathway using a combination of mass spectrometry, RNA-seq, enzyme assays, RNAi and phylogenomics in different non-model species. Our results reveal hundreds of acylsugars produced across the Solanaceae family and even within a single plant, built on simple sugar cores. The relatively short biosynthetic pathway experienced repeated cycles of innovation over the last 100 million years that include gene duplication and divergence, gene loss, evolution of substrate preference and promiscuity. This study provides mechanistic insights into the emergence of plant chemical novelty, and offers a template for investigating the ~300,000 non-model plant species that remain underexplored.

TEM study of 〈110〉-type 35.26° dislocations specially induced by polishing of SrTiO₃ single crystals.

PubMed

Jin, L; Guo, X; Jia, C L

2013-11-01

The dislocations created by mechanical polishing of SrTiO₃ (100) single crystals were investigated by means of transmission electron microscopy (TEM) techniques combined with scanning TEM (STEM) techniques. A high density of dislocations was observed in the surface layer with a thickness of about 5 μm. These dislocations were found to be straight and highly aligned along the 〈111〉 directions. In most cases they appear in pairs or as a bundle. The nature of the dislocations was determined as mixed 〈110〉-type with the line vector t=〈111〉. They are 〈110〉-type 35.26° dislocations. The isolated 〈110〉-type 35.26° dislocations possess a compact core structure with a core spreading of ~0.5 nm. Dissociation of the dislocation occurs on the {1−10} glide plane, leading to the formation of two b=a/2〈110〉 partials separated by a stacking fault. The separation of the two partials was estimated to be 2.53 ± 0.32 nm based on a cross-correlation analysis of atomic-resolution images. Our results provide a solid experimental evidence for this special type of dislocation in SrTiO₃. The high density of straight and highly 〈111〉-orientated dislocations is expected to have an important influence on the anisotropy in electrical and mass transport properties. © 2013 Elsevier B.V. All rights reserved.

75 FR 6043 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-05

... Infectious Diseases Special Emphasis Panel; Nonhuman Primate Cellular Immunology Core for HIV Vaccine..., Allergy, Immunology, and Transplantation Research; 93.856, Microbiology and Infectious Diseases Research...

40 CFR 467.41 - Specialized definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... definitions. For the purpose of this subpart: (a) The “core” of the forging subcategory shall include forging... operation not previously included in the core, performed on-site, following or preceding the forging...

40 CFR 467.41 - Specialized definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... definitions. For the purpose of this subpart: (a) The “core” of the forging subcategory shall include forging... operation not previously included in the core, performed on-site, following or preceding the forging...

Efficiency of static core turn-off in a system-on-a-chip with variation

DOEpatents

Cher, Chen-Yong; Coteus, Paul W; Gara, Alan; Kursun, Eren; Paulsen, David P; Schuelke, Brian A; Sheets, II, John E; Tian, Shurong

2013-10-29

A processor-implemented method for improving efficiency of a static core turn-off in a multi-core processor with variation, the method comprising: conducting via a simulation a turn-off analysis of the multi-core processor at the multi-core processor's design stage, wherein the turn-off analysis of the multi-core processor at the multi-core processor's design stage includes a first output corresponding to a first multi-core processor core to turn off; conducting a turn-off analysis of the multi-core processor at the multi-core processor's testing stage, wherein the turn-off analysis of the multi-core processor at the multi-core processor's testing stage includes a second output corresponding to a second multi-core processor core to turn off; comparing the first output and the second output to determine if the first output is referring to the same core to turn off as the second output; outputting a third output corresponding to the first multi-core processor core if the first output and the second output are both referring to the same core to turn off.

75 FR 51280 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-19

... Infectious Diseases Special Emphasis Panel, Nonhuman Primate Core Humoral Immunology Vaccine Laboratory. Date..., [email protected] . (Catalogue of Federal Domestic Assistance Program Nos. 93.855, Allergy, Immunology...

Functional perspectives on emotion, behavior, and cognition.

PubMed

Lench, Heather C; Darbor, Kathleen E; Berg, Logan A

2013-12-01

This Editorial reviews the challenges and advantages posed by a functional perspective on the relationships among emotion, behavior, and cognition. We identify the core themes among the articles published as part of this Special Issue. The articles generally address two important questions: (1) are emotions functional and what is their impact on behavioral and cognitive processes, and (2) how do the interactions among emotion, cognition, and behavior play out in particular situations that present adaptive challenges? We also identify two core questions raised by the articles included in this Special Issue. Future research must address the extent to which emotions are best represented as discrete emotional constructs (e.g., anger, sadness, fear) versus emotions that vary along dimensions, such as valence and arousal. Functional perspectives would also be facilitated by identification of situations or environments that are likely to elicit particular emotions and reactions.

Relative stability of core groups in pollination networks in a biodiversity hotspot over four years.

PubMed

Fang, Qiang; Huang, Shuang-Quan

2012-01-01

Plants and their pollinators form pollination networks integral to the evolution and persistence of species in communities. Previous studies suggest that pollination network structure remains nested while network composition is highly dynamic. However, little is known about temporal variation in the structure and function of plant-pollinator networks, especially in species-rich communities where the strength of pollinator competition is predicted to be high. Here we quantify temporal variation of pollination networks over four consecutive years in an alpine meadow in the Hengduan Mountains biodiversity hotspot in China. We found that ranked positions and idiosyncratic temperatures of both plants and pollinators were more conservative between consecutive years than in non-consecutive years. Although network compositions exhibited high turnover, generalized core groups--decomposed by a k-core algorithm--were much more stable than peripheral groups. Given the high rate of turnover observed, we suggest that identical plants and pollinators that persist for at least two successive years sustain pollination services at the community level. Our data do not support theoretical predictions of a high proportion of specialized links within species-rich communities. Plants were relatively specialized, exhibiting less variability in pollinator composition at pollinator functional group level than at the species level. Both specialized and generalized plants experienced narrow variation in functional pollinator groups. The dynamic nature of pollination networks in the alpine meadow demonstrates the potential for networks to mitigate the effects of fluctuations in species composition in a high biodiversity area.

Face Sheet/Core Disbond Growth in Honeycomb Sandwich Panels Subjected to Ground-Air-Ground Pressurization and In-Plane Loading

NASA Technical Reports Server (NTRS)

Chen, Zhi M.; Krueger, Ronald; Rinker, Martin

2015-01-01

Typical damage modes in light honeycomb sandwich structures include face sheet/core disbonding and core fracture, both of which can pose a threat to the structural integrity of a component. These damage modes are of particular interest to aviation certification authorities since several in-service occurrences, such as rudder structural failure and other control surface malfunctions, have been attributed to face sheet/core disbonding. Extensive studies have shown that face sheet/core disbonding and core fracture can lead to damage propagation caused by internal pressure changes in the core. The increasing use of composite sandwich construction in aircraft applications makes it vitally important to understand the effect of ground-air-ground (GAG) cycles and conditions such as maneuver and gust loads on face sheet/core disbonding. The objective of the present study was to use a fracture mechanics based approach developed earlier to evaluate the loading at the disbond front caused by ground-air-ground pressurization and in-plane loading. A honeycomb sandwich panel containing a circular disbond at one face sheet/core interface was modeled with three-dimensional (3D) solid finite elements. The disbond was modeled as a discrete discontinuity and the strain energy release rate along the disbond front was computed using the Virtual Crack Closure Technique (VCCT). Special attention was paid to the pressure-deformation coupling which can decrease the pressure load within the disbonded sandwich section significantly when the structure is highly deformed. The commercial finite element analysis software, Abaqus/Standard, was used for the analyses. The recursive pressure-deformation coupling problem was solved by representing the entrapped air in the honeycomb cells as filled cavities in Abaqus/Standard. The results show that disbond size, face sheet thickness and core thickness are important parameters that determine crack tip loading at the disbond front. Further, the pressure-deformation coupling was found to have an important load decreasing effect [6]. In this paper, a detailed problem description is provided first. Second, the analysis methodology is presented. The fracture mechanics approach used is described and the specifics of the finite element model, including the fluid-filled cavities, are introduced. Third, the initial model verification and validation are discussed. Fourth, the findings from a closely related earlier study [6] are summarized. These findings provided the basis for the current investigation. Fifth, an aircraft ascent scenario from 0 to 12192 m (0 to 40000 ft) is considered and the resulting crack tip loading at the disbond front is determined. In-plane loading to simulate maneuvers and gust conditions are also considered. Sixth, the results are shown for a curved panel, which was used to simulate potential fuselage applications. Finally, a brief summary of observations is presented and recommendations for improvement are provided.

ORBS, ORCS, OACS, a Software Suite for Data Reduction and Analysis of the Hyperspectral Imagers SITELLE and SpIOMM

NASA Astrophysics Data System (ADS)

Martin, T.; Drissen, L.; Joncas, G.

2015-09-01

SITELLE (installed in 2015 at the Canada-France-Hawaii Telescope) and SpIOMM (a prototype attached to the Observatoire du Mont-Mégantic) are the first Imaging Fourier Transform Spectrometers (IFTS) capable of obtaining a hyperspectral data cube which samples a 12 arc minutes field of view into four millions of visible spectra. The result of each observation is made up of two interferometric data cubes which need to be merged, corrected, transformed and calibrated in order to get a spectral cube of the observed region ready to be analysed. ORBS is a fully automatic data reduction software that has been entirely designed for this purpose. The data size (up to 68 Gb for larger science cases) and the computational needs have been challenging and the highly parallelized object-oriented architecture of ORBS reflects the solutions adopted which made possible to process 68 Gb of raw data in less than 11 hours using 8 cores and 22.6 Gb of RAM. It is based on a core framework (ORB) that has been designed to support the whole software suite for data analysis (ORCS and OACS), data simulation (ORUS) and data acquisition (IRIS). They all aim to provide a strong basis for the creation and development of specialized analysis modules that could benefit the scientific community working with SITELLE and SpIOMM.

Application of Laser Induced Breakdown Spectroscopy under Polar Conditions

NASA Astrophysics Data System (ADS)

Clausen, J. L.; Hark, R.; Bol'shakov, A.; Plumer, J.

2015-12-01

Over the past decade our research team has evaluated the use of commercial-off-the-shelf laser-induced breakdown spectroscopy (LIBS) for chemical analysis of snow and ice samples under polar conditions. One avenue of research explored LIBS suitability as a detector of paleo-climate proxy indicators (Ca, K, Mg, and Na) in ice as it relates to atmospheric circulation. LIBS results revealed detection of peaks for C and N, consistent with the presence of organic material, as well as major ions (Ca, K, Mg, and Na) and trace metals (Al, Cu, Fe, Mn, Ti). The detection of Ca, K, Mg, and Na confirmed that LIBS has sufficient sensitivity to be used as a tool for characterization of paleo-climate proxy indicators in ice-core samples. Techniques were developed for direct analysis of ice as well as indirect measurements of ice via melting and filtering. Pitfalls and issues of direct ice analysis using several cooling techniques to maintain ice integrity will be discussed. In addition, a new technique, laser ablation molecular isotopic spectroscopy (LAMIS) was applied to detection of hydrogen and oxygen isotopes in ice as isotopic analysis of ice is the main tool in paleoclimatology and glaciology studies. Our results demonstrated that spectra of hydroxyl isotopologues 16OH, 18OH, and 16OD can be recorded with a compact spectrograph to determine hydrogen and oxygen isotopes simultaneously. Quantitative isotopic calibration for ice analysis can be accomplished using multivariate chemometric regression as previously realized for water vapor. Analysis with LIBS and LAMIS required no special sample preparation and was about ten times faster than analysis using ICP-MS. Combination of the two techniques in one portable instrument for in-field analysis appears possible and would eliminate the logistical and cost issues associated with ice core management.

Fukushima Daiichi Unit 1 Ex-Vessel Prediction: Core-Concrete Interaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robb, Kevin R.; Farmer, Mitchell T.; Francis, Matthew W.

Lower head failure and corium-concrete interaction were predicted to occur at Fukushima Daiichi Unit 1 (1F1) by several different system-level code analyses, including MELCOR v2.1 and MAAP5. Although these codes capture a wide range of accident phenomena, they do not contain detailed models for ex-vessel core melt behavior. However, specialized codes exist for the analysis of ex-vessel melt spreading (e.g., MELTSPREAD) and long-term debris coolability (e.g., CORQUENCH). On this basis, in this paper an analysis was carried out to further evaluate ex-vessel behavior for 1F1 using MELTSPREAD and CORQUENCH. Best-estimate melt pour conditions predicted by MELCOR v2.1 and MAAP5 weremore » used as input. MELTSPREAD was then used to predict the spatially dependent melt conditions and extent of spreading during relocation from the vessel. The results of the MELTSPREAD analysis are reported in a companion paper. This information was used as input for the long-term debris coolability analysis with CORQUENCH. For the MELCOR-based melt pour scenario, CORQUENCH predicted the melt would readily cool within 2.5 h after the pour, and the sumps would experience limited ablation (approximately 18 cm) under water-flooded conditions. Finally, for the MAAP-based melt pour scenarios, CORQUENCH predicted that the melt would cool in approximately 22.5 h, and the sumps would experience approximately 65 cm of concrete ablation under water-flooded conditions.« less

Fukushima Daiichi Unit 1 Ex-Vessel Prediction: Core-Concrete Interaction

DOE PAGES

Robb, Kevin R.; Farmer, Mitchell T.; Francis, Matthew W.

2016-10-31

Lower head failure and corium-concrete interaction were predicted to occur at Fukushima Daiichi Unit 1 (1F1) by several different system-level code analyses, including MELCOR v2.1 and MAAP5. Although these codes capture a wide range of accident phenomena, they do not contain detailed models for ex-vessel core melt behavior. However, specialized codes exist for the analysis of ex-vessel melt spreading (e.g., MELTSPREAD) and long-term debris coolability (e.g., CORQUENCH). On this basis, in this paper an analysis was carried out to further evaluate ex-vessel behavior for 1F1 using MELTSPREAD and CORQUENCH. Best-estimate melt pour conditions predicted by MELCOR v2.1 and MAAP5 weremore » used as input. MELTSPREAD was then used to predict the spatially dependent melt conditions and extent of spreading during relocation from the vessel. The results of the MELTSPREAD analysis are reported in a companion paper. This information was used as input for the long-term debris coolability analysis with CORQUENCH. For the MELCOR-based melt pour scenario, CORQUENCH predicted the melt would readily cool within 2.5 h after the pour, and the sumps would experience limited ablation (approximately 18 cm) under water-flooded conditions. Finally, for the MAAP-based melt pour scenarios, CORQUENCH predicted that the melt would cool in approximately 22.5 h, and the sumps would experience approximately 65 cm of concrete ablation under water-flooded conditions.« less

Linguistic explanation and domain specialization: a case study in bound variable anaphora.

PubMed

Adger, David; Svenonius, Peter

2015-01-01

The core question behind this Frontiers research topic is whether explaining linguistic phenomena requires appeal to properties of human cognition that are specialized to language. We argue here that investigating this issue requires taking linguistic research results seriously, and evaluating these for domain-specificity. We present a particular empirical phenomenon, bound variable interpretations of pronouns dependent on a quantifier phrase, and argue for a particular theory of this empirical domain that is couched at a level of theoretical depth which allows its principles to be evaluated for domain-specialization. We argue that the relevant principles are specialized when they apply in the domain of language, even if analogs of them are plausibly at work elsewhere in cognition or the natural world more generally. So certain principles may be specialized to language, though not, ultimately, unique to it. Such specialization is underpinned by ultimately biological factors, hence part of UG.

Linguistic explanation and domain specialization: a case study in bound variable anaphora

PubMed Central

Adger, David; Svenonius, Peter

2015-01-01

The core question behind this Frontiers research topic is whether explaining linguistic phenomena requires appeal to properties of human cognition that are specialized to language. We argue here that investigating this issue requires taking linguistic research results seriously, and evaluating these for domain-specificity. We present a particular empirical phenomenon, bound variable interpretations of pronouns dependent on a quantifier phrase, and argue for a particular theory of this empirical domain that is couched at a level of theoretical depth which allows its principles to be evaluated for domain-specialization. We argue that the relevant principles are specialized when they apply in the domain of language, even if analogs of them are plausibly at work elsewhere in cognition or the natural world more generally. So certain principles may be specialized to language, though not, ultimately, unique to it. Such specialization is underpinned by ultimately biological factors, hence part of UG. PMID:26441791

Naval Special Warfare: Identifying and Prioritizing Core Attributes of the Profession

DTIC Science & Technology

2014-12-01

literature review supports the need for research that is designed to advance the NSW profession. Analytic rigor could inform how NSW should refine its...B. SKILLS REQUIRED - WHAT (QUESTIONS 10–25, 26, 30) This research was designed to answer the following question: “What are the practical skills...NSW PRODEV: Naval Special Warfare Professional Development This research is designed to answer the following question. What are the practical

Parallelization of combinatorial search when solving knapsack optimization problem on computing systems based on multicore processors

NASA Astrophysics Data System (ADS)

Rahman, P. A.

2018-05-01

This scientific paper deals with the model of the knapsack optimization problem and method of its solving based on directed combinatorial search in the boolean space. The offered by the author specialized mathematical model of decomposition of the search-zone to the separate search-spheres and the algorithm of distribution of the search-spheres to the different cores of the multi-core processor are also discussed. The paper also provides an example of decomposition of the search-zone to the several search-spheres and distribution of the search-spheres to the different cores of the quad-core processor. Finally, an offered by the author formula for estimation of the theoretical maximum of the computational acceleration, which can be achieved due to the parallelization of the search-zone to the search-spheres on the unlimited number of the processor cores, is also given.

Theoretical Developments in Understanding Massive Star Formation

NASA Technical Reports Server (NTRS)

Yorke, Harold W.; Bodenheimer, Peter

2007-01-01

Except under special circumstances massive stars in galactic disks will form through accretion. The gravitational collapse of a molecular cloud core will initially produce one or more low mass quasi-hydrostatic objects of a few Jupiter masses. Through subsequent accretion the masses of these cores grow as they simultaneously evolve toward hydrogen burning central densities and temperatures. We review the evolution of accreting (proto-)stars, including new results calculated with a publicly available stellar evolution code written by the authors.

Largely improved the low temperature toughness of acrylonitrile-styrene-acrylate (ASA) resin: Fabricated a core-shell structure of two elastomers through the differences of interfacial tensions

NASA Astrophysics Data System (ADS)

Mao, Zepeng; Zhang, Jun

2018-06-01

The phase morphology of two elastomers (i.e., chlorinated polyethylene (CPE) and polybutadiene rubber (BR)) were devised to be a core-shell structure in acrylonitrile-styrene-acrylate (ASA) resin matrix, via the interfacial tension differences of polymer pairs. Selective extraction test and scanning electron microscopy (SEM) were utilized to verify this special phase morphology. The results demonstrated that the core-shell structure, BR core and CPE shell, significantly contributed to improve the low temperature toughness of ASA/CPE/BR ternary blends, which may be because the nonpolar BR core was segregated from polar ASA by the CPE shell. The CPE shell served dual functions: Not only did it play compatibilizing effect in the interface between BR and ASA matrix, but it also toughened the blends at 25 and 0 °C. The blends of ASA/CPE/BR (100/27/3, w/w/w) and ASA/CPE/BR (100/22/8, w/w/w) showed the peak impact strengths at about 28 and 9 kJ/m2 at 0 and -30 °C, respectively, which were higher than both that of ASA/CPE/BR (100/30/0, w/w/w) and ASA/CPE/BR (100/0/30, w/w/w). Moreover, the impact strength of ternary blends at room temperature kept at 40 kJ/m2 when BR content was lower than 10 phr. Other characterizations including contact angle measurement, dynamic mechanical thermal analysis (DMTA), morphology of impact-fractured surfaces, tensile properties, flexural properties, and Fourier transform infrared spectroscopy (FTIR) were measured as well.

Applying the concept of quality of life to Israeli special education programs: a national curriculum for enhanced autonomy in students with special needs.

PubMed

Reiter, Shunit; Schalock, Robert L

2008-03-01

This study provides a description of the design and development of guidelines and programs for a national core curriculum for special education in Israel. Israel was exposed during the 1970s to the ideology of normalization. Later on, toward the end of the 1980s, the concept of quality of life was added. Several research studies were conducted, resulting in the following core ideas about education: a shift of emphasis from teaching independent-living skills to teaching autonomy, self-awareness, self-direction, and interdependence is required. On the basis of these ideas, a new model of instruction was devised and termed the 'cycle of internalized learning' (CIL). The CIL is based on a holistic orientation toward the student and builds on abilities rather than disabilities. The peer group is the basic unit of instruction. Attention is on processes and outcomes. The CIL involves several clearly defined teaching steps: (i) opening--the presentation of the subject matter; (ii) discussion--a conceptual analysis of the subject; (iii) open conversation--students discuss the issues they raised during the first session, express their personal life experiences while applying the new concepts they learned, and suggest possible solutions to problems; (iv) trying out the solutions suggested by students; and (v) repeated discussions, to arrive at personal and social conclusions. Currently there are three published units of the CIL: (i) Social Education, (ii) Career Education, and (iii) Towards Leaving Home for Independent Living in the Community. The fourth unit, on citizenship education through the use of computers, is in its final stages of preparation. The success of the implementation of the program is expressed both at the students' level--as an enhanced sense of self-worth and self-confidence, as well as enhanced academic achievements and social skills--and at the teachers' level--as a paradigm shift from a medical model of approach to students with disabilities to a social and humanistic one.

Evolution of larval life mode of Oecophoridae (Lepidoptera: Gelechioidea) inferred from molecular phylogeny.

PubMed

Kim, Sora; Kaila, Lauri; Lee, Seunghwan

2016-08-01

Phylogenetic relationships within family Oecophoridae have been poorly understood. Consequently the subfamily and genus level classifications with this family problematic. A comprehensive phylogenetic analysis of Oecophoridae, the concealer moths, was performed based on analysis of 4444 base pairs of mitochondrial COI, nuclear ribosomal RNA genes (18S and 28S) and nuclear protein coding genes (IDH, MDH, Rps5, EF1a and wingless) for 82 taxa. Data were analyzed using maximum likelihood (ML), parsimony (MP) and Bayesian (BP) phylogenetic frameworks. Phylogenetic analyses indicated that (i) genera Casmara, Tyrolimnas and Pseudodoxia did not belong to Oecophoridae, suggesting that Oecophoridae s. authors was not monophyletic; (ii) other oecophorids comprising two subfamilies, Pleurotinae and Oecophorinae, were nested within the same clade, and (iii) Martyringa, Acryptolechia and Periacmini were clustered with core Xyloryctidae. They appeared to be sister lineage with core Oecophoridae. BayesTraits were implemented to explore the ancestral character states to infer historical microhabitat patterns and sheltering strategy of larvae. Reconstruction of ancestral microhabitat of oecophorids indicated that oecophorids might have evolved from dried plant feeders and further convergently specialized. The ancestral larva sheltering strategy of oecophorids might have used a silk tube by making itself, shifting from mining leaves. Copyright © 2016 Elsevier Inc. All rights reserved.

Preface to Special Topic: Acoustic Metamaterials and Metasurfaces

NASA Astrophysics Data System (ADS)

Assouar, Badreddine

2018-03-01

The advent of acoustic metamaterials in the beginning of 2000s and very recently of acoustic metasurfaces has created tremendous excitement and efforts in the field of materials science and physics by introducing and building real transformative research and dealing with unprecedented physics and applications. The acoustic/elastic metamaterials and metasurfaces, which can simply be described as designed artificial materials with unusual physical properties, form the core of the present Special Topic published by the Journal of Applied Physics.

Fitness characteristics of a suburban special weapons and tactics team.

PubMed

Pryor, Riana R; Colburn, Deanna; Crill, Matthew T; Hostler, David P; Suyama, J

2012-03-01

Special Weapons and Tactics (SWAT) operators are specialized law enforcement officers who traditionally perform their duties with higher anticipated workloads because of additional body armor, weapons, and equipment used for enhanced operations and protection. This elevated workload increases the need for SWAT operators to improve or maintain their physical fitness to consistently perform routine operations. Typical tasks require trunk rotation, overhead upper extremity use, upper and lower body strength use, and long waiting periods followed by explosive movements while wearing additional equipment. Eleven male SWAT operators from 1 SWAT team performed flexibility, strength, power, and aerobic capacity tests and a variety of job-related tasks. Data were compared with age- and gender-based normative data. Fitness testing revealed that officers ranked high on tests of muscular strength (leg strength, 90th percentile; bench press, 85th percentile); however, body composition (55th percentile), core body strength, and flexibility ranked lower. Furthermore, aerobic capacity and muscular power had a wide range of scores and were also not ideal to support maximal performance during routine operations. These data can assist exercise specialists choose fitness programs specifically for job-related tasks of SWAT operators when creating fitness programs. Fitness programming for law enforcement should focus on improving aerobic fitness, flexibility, core strength, and muscular power while maintaining muscular strength to meet the needs of these specialized officers.

Hardware accelerated high performance neutron transport computation based on AGENT methodology

NASA Astrophysics Data System (ADS)

Xiao, Shanjie

The spatial heterogeneity of the next generation Gen-IV nuclear reactor core designs brings challenges to the neutron transport analysis. The Arbitrary Geometry Neutron Transport (AGENT) AGENT code is a three-dimensional neutron transport analysis code being developed at the Laboratory for Neutronics and Geometry Computation (NEGE) at Purdue University. It can accurately describe the spatial heterogeneity in a hierarchical structure through the R-function solid modeler. The previous version of AGENT coupled the 2D transport MOC solver and the 1D diffusion NEM solver to solve the three dimensional Boltzmann transport equation. In this research, the 2D/1D coupling methodology was expanded to couple two transport solvers, the radial 2D MOC solver and the axial 1D MOC solver, for better accuracy. The expansion was benchmarked with the widely applied C5G7 benchmark models and two fast breeder reactor models, and showed good agreement with the reference Monte Carlo results. In practice, the accurate neutron transport analysis for a full reactor core is still time-consuming and thus limits its application. Therefore, another content of my research is focused on designing a specific hardware based on the reconfigurable computing technique in order to accelerate AGENT computations. It is the first time that the application of this type is used to the reactor physics and neutron transport for reactor design. The most time consuming part of the AGENT algorithm was identified. Moreover, the architecture of the AGENT acceleration system was designed based on the analysis. Through the parallel computation on the specially designed, highly efficient architecture, the acceleration design on FPGA acquires high performance at the much lower working frequency than CPUs. The whole design simulations show that the acceleration design would be able to speedup large scale AGENT computations about 20 times. The high performance AGENT acceleration system will drastically shortening the computation time for 3D full-core neutron transport analysis, making the AGENT methodology unique and advantageous, and thus supplies the possibility to extend the application range of neutron transport analysis in either industry engineering or academic research.

Double layered tailorable advanced blanket insulation

NASA Technical Reports Server (NTRS)

Falstrup, D.

1983-01-01

An advanced flexible reusable surface insulation material for future space shuttle flights was investigated. A conventional fly shuttle loom with special modifications to weave an integral double layer triangular core fabric from quartz yarn was used. Two types of insulating material were inserted into the cells of the fabric, and a procedure to accomplish this was developed. The program is follow up of a program in which single layer rectangular cell core fabrics are woven and a single type of insulating material was inserted into the cells.

Deterministic Modeling of the High Temperature Test Reactor with DRAGON-HEXPEDITE

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. Ortensi; M.A. Pope; R.M. Ferrer

2010-10-01

The Idaho National Laboratory (INL) is tasked with the development of reactor physics analysis capability of the Next Generation Nuclear Power (NGNP) project. In order to examine the INL’s current prismatic reactor analysis tools, the project is conducting a benchmark exercise based on modeling the High Temperature Test Reactor (HTTR). This exercise entails the development of a model for the initial criticality, a 19 fuel column thin annular core, and the fully loaded core critical condition with 30 fuel columns. Special emphasis is devoted to physical phenomena and artifacts in HTTR that are similar to phenomena and artifacts in themore » NGNP base design. The DRAGON code is used in this study since it offers significant ease and versatility in modeling prismatic designs. DRAGON can generate transport solutions via Collision Probability (CP), Method of Characteristics (MOC) and Discrete Ordinates (Sn). A fine group cross-section library based on the SHEM 281 energy structure is used in the DRAGON calculations. The results from this study show reasonable agreement in the calculation of the core multiplication factor with the MC methods, but a consistent bias of 2–3% with the experimental values is obtained. This systematic error has also been observed in other HTTR benchmark efforts and is well documented in the literature. The ENDF/B VII graphite and U235 cross sections appear to be the main source of the error. The isothermal temperature coefficients calculated with the fully loaded core configuration agree well with other benchmark participants but are 40% higher than the experimental values. This discrepancy with the measurement partially stems from the fact that during the experiments the control rods were adjusted to maintain criticality, whereas in the model, the rod positions were fixed. In addition, this work includes a brief study of a cross section generation approach that seeks to decouple the domain in order to account for neighbor effects. This spectral interpenetration is a dominant effect in annular HTR physics. This analysis methodology should be further explored in order to reduce the error that is systematically propagated in the traditional generation of cross sections.« less

Phylogenetic analysis of the core histone doublet and DNA topo II genes of Marseilleviridae: evidence of proto-eukaryotic provenance.

PubMed

Erives, Albert J

2017-11-28

While the genomes of eukaryotes and Archaea both encode the histone-fold domain, only eukaryotes encode the core histone paralogs H2A, H2B, H3, and H4. With DNA, these core histones assemble into the nucleosomal octamer underlying eukaryotic chromatin. Importantly, core histones for H2A and H3 are maintained as neofunctionalized paralogs adapted for general bulk chromatin (canonical H2 and H3) or specialized chromatin (H2A.Z enriched at gene promoters and cenH3s enriched at centromeres). In this context, the identification of core histone-like "doublets" in the cytoplasmic replication factories of the Marseilleviridae (MV) is a novel finding with possible relevance to understanding the origin of eukaryotic chromatin. Here, we analyze and compare the core histone doublet genes from all known MV genomes as well as other MV genes relevant to the origin of the eukaryotic replisome. Using different phylogenetic approaches, we show that MV histone domains encode obligate H2B-H2A and H4-H3 dimers of possible proto-eukaryotic origin. MV core histone moieties form sister clades to each of the four eukaryotic clades of canonical and variant core histones. This suggests that MV core histone moieties diverged prior to eukaryotic neofunctionalizations associated with paired linear chromosomes and variant histone octamer assembly. We also show that MV genomes encode a proto-eukaryotic DNA topoisomerase II enzyme that forms a sister clade to eukaryotes. This is a relevant finding given that DNA topo II influences histone deposition and chromatin compaction and is the second most abundant nuclear protein after histones. The combined domain architecture and phylogenomic analyses presented here suggest that a primitive origin for MV histone genes is a more parsimonious explanation than horizontal gene transfers + gene fusions + sufficient divergence to eliminate relatedness to eukaryotic neofunctionalizations within the H2A and H3 clades without loss of relatedness to each of the four core histone clades. We thus suggest MV histone doublet genes and their DNA topo II gene possibly were acquired from an organism with a chromatinized replisome that diverged prior to the origin of eukaryotic core histone variants for H2/H2A.Z and H3/cenH3. These results also imply that core histones were utilized ancestrally in viral DNA compaction and/or protection from host endonucleases.

Predicting extractives content of Eucalyptus bosistoana F. Muell. Heartwood from stem cores by near infrared spectroscopy

NASA Astrophysics Data System (ADS)

Li, Yanjie; Altaner, Clemens

2018-06-01

Time and resource are the restricting factors for the wider use of chemical information of wood in tree breeding programs. NIR offers an advantage over wet-chemical analysis in these aspects and is starting to be used for tree breeding. This work describes the development of a NIR-based assessment of extractive content in heartwood of E. bosistoana, which does not require milling and conditioning of the samples. This was achieved by applying the signal processing algorithms (external parameter orthogonalisation (EPO) and significance multivariate correlation (sMC)) to spectra obtained from solid wood cores, which were able to correct for moisture content, grain direction and sample form. The accuracy of extractive content predictions was further improved by variable selection, resulting in a root mean square error of 1.27%. Considering the range of extractive content in E. bosistoana heartwood of 1.3 to 15.0%, the developed NIR calibration has the potential to be used in an E. bosistoana breeding program or to assess the special variation in extractive content throughout a stem.

Modeling and testing of ethernet transformers

NASA Astrophysics Data System (ADS)

Bowen, David

2011-12-01

Twisted-pair Ethernet is now the standard home and office last-mile network technology. For decades, the IEEE standard that defines Ethernet has required electrical isolation between the twisted pair cable and the Ethernet device. So, for decades, every Ethernet interface has used magnetic core Ethernet transformers to isolate Ethernet devices and keep users safe in the event of a potentially dangerous fault on the network media. The current state-of-the-art Ethernet transformers are miniature (<5mm diameter) ferrite-core toroids wrapped with approximately 10 to 30 turns of wire. As small as current Ethernet transformers are, they still limit further Ethernet device miniaturization and require a separate bulky package or jack housing. New coupler designs must be explored which are capable of exceptional miniaturization or on-chip fabrication. This dissertation thoroughly explores the performance of the current commercial Ethernet transformers to both increase understanding of the device's behavior and outline performance parameters for replacement devices. Lumped element and distributed circuit models are derived; testing schemes are developed and used to extract model parameters from commercial Ethernet devices. Transfer relation measurements of the commercial Ethernet transformers are compared against the model's behavior and it is found that the tuned, distributed models produce the best transfer relation match to the measured data. Process descriptions and testing results on fabricated thin-film dielectric-core toroid transformers are presented. The best results were found for a 32-turn transformer loaded with 100Ω, the impedance of twisted pair cable. This transformer gave a flat response from about 10MHz to 40MHz with a height of approximately 0.45. For the fabricated transformer structures, theoretical methods to determine resistance, capacitance and inductance are presented. A special analytical and numerical analysis of the fabricated transformer inductance is presented. Planar cuts of magnetic slope fields around the dielectric-core toroid are shown that describe the effect of core height and winding density on flux uniformity without a magnetic core.

Using DSDP/ODP/IODP core photographs and digital images in the classroom

NASA Astrophysics Data System (ADS)

Pereira, Hélder; Berenguer, Jean-Luc

2017-04-01

Since the late 1960's, several scientific ocean drilling programmes have been uncovering the history of the Earth hidden beneath the seafloor. The adventure began in 1968 with the Deep Sea Drilling Project (DSDP) and its special drill ship, the Glomar Challenger. The next stage was the Ocean Drilling Program (ODP) launched in 1985 with a new drill ship, the JOIDES Resolution. The exploration of the ocean seafloor continued, between 2003 and 2013, through the Integrated Ocean Drilling Program (IODP). During that time, in addition to the JOIDES Resolution, operated by the US, the scientists had at their service the Chikyu, operated by Japan, and Mission-Specific-Platforms, funded and implemented by the European Consortium for Ocean Research Drilling. Currently, scientific ocean drilling continues through the collaboration of scientists from 25 nations within the International Ocean Discovery Program (IODP). Over the last 50 years, the scientific ocean drilling expeditions conducted by these programmes have drilled and cored more than 3500 holes. The numerous sediment and rock samples recovered from the ocean floor have provided important insight on the active biological, chemical, and geological processes that have shaped the Earth over millions of years. During an expedition, once the 9.5-meter long cores arrive from the seafloor, the technicians label and cut them into 1.5-meter sections. Next, the shipboard scientists perform several analysis using non-destructive methods. Afterward, the technicians split the cores into two halves, the "working half", which scientists sample and use aboard the drilling platform, and the "archive half", which is kept in untouched condition after being visually described and photographed with a digital imaging system. The shipboard photographer also takes several close-up pictures of the archive-half core sections. This work presents some examples of how teachers can use DSDP/ODP/IODP core photographs and digital images, available through the Janus and LIMS online databases, to develop inquiry-based learning activities for secondary level students.

The INTIMATE event stratigraphy of the last glacial period

NASA Astrophysics Data System (ADS)

Olander Rasmussen, Sune; Svensson, Anders

2015-04-01

The North Atlantic INTIMATE (INtegration of Ice-core, MArine and TErrestrial records) group has previously recommended an Event Stratigraphy approach for the synchronisation of records of the Last Termination using the Greenland ice core records as the regional stratotypes. A key element of these protocols has been the formal definition of numbered Greenland Stadials (GS) and Greenland Interstadials (GI) within the past glacial period as the Greenland expressions of the characteristic Dansgaard-Oeschger events that represent cold and warm phases of the North Atlantic region, respectively. Using a recent synchronization of the NGRIP, GRIP, and GISP2 ice cores that allows the parallel analysis of all three records on a common time scale, we here present an extension of the GS/GI stratigraphic template to the entire glacial period. In addition to the well-known sequence of Dansgaard-Oeschger events that were first defined and numbered in the ice core records more than two decades ago, a number of short-lived climatic oscillations have been identified in the three synchronized records. Some of these events have been observed in other studies, but we here propose a consistent scheme for discriminating and naming all the significant climatic events of the last glacial period that are represented in the Greenland ice cores. In addition to presenting the updated event stratigraphy, we make a series of recommendations on how to refer to these periods in a way that promotes unambiguous comparison and correlation between different proxy records, providing a more secure basis for investigating the dynamics and fundamental causes of these climatic perturbations. The work presented is a part of a newly published paper in an INTIMATE special issue of Quaternary Science Reviews: Rasmussen et al., 'A stratigraphic framework for abrupt climatic changes during the Last Glacial period based on three synchronized Greenland ice-core records: refining and extending the INTIMATE event stratigraphy', Quaternary Science Reviews, vol. 106, p. 14-24, 2014.

Canada's neglected tropical disease research network: who's in the core-who's on the periphery?

PubMed

Phillips, Kaye; Kohler, Jillian Clare; Pennefather, Peter; Thorsteinsdottir, Halla; Wong, Joseph

2013-01-01

This study designed and applied accessible yet systematic methods to generate baseline information about the patterns and structure of Canada's neglected tropical disease (NTD) research network; a network that, until recently, was formed and functioned on the periphery of strategic Canadian research funding. MULTIPLE METHODS WERE USED TO CONDUCT THIS STUDY, INCLUDING: (1) a systematic bibliometric procedure to capture archival NTD publications and co-authorship data; (2) a country-level "core-periphery" network analysis to measure and map the structure of Canada's NTD co-authorship network including its size, density, cliques, and centralization; and (3) a statistical analysis to test the correlation between the position of countries in Canada's NTD network ("k-core measure") and the quantity and quality of research produced. Over the past sixty years (1950-2010), Canadian researchers have contributed to 1,079 NTD publications, specializing in Leishmania, African sleeping sickness, and leprosy. Of this work, 70% of all first authors and co-authors (n = 4,145) have been Canadian. Since the 1990s, however, a network of international co-authorship activity has been emerging, with representation of researchers from 62 different countries; largely researchers from OECD countries (e.g. United States and United Kingdom) and some non-OECD countries (e.g. Brazil and Iran). Canada has a core-periphery NTD international research structure, with a densely connected group of OECD countries and some African nations, such as Uganda and Kenya. Sitting predominantly on the periphery of this research network is a cluster of 16 non-OECD nations that fall within the lowest GDP percentile of the network. The publication specialties, composition, and position of NTD researchers within Canada's NTD country network provide evidence that while Canadian researchers currently remain the overall gatekeepers of the NTD research they generate; there is opportunity to leverage existing research collaborations and help advance regions and NTD areas that are currently under-developed.

Results of Tests on Radiators for Aircraft Engines

NASA Technical Reports Server (NTRS)

Dickinson, H C; James, W S; Kleinschmidt, R V

1920-01-01

Part 1 is to present the results of tests on 56 types of core in a form convenient for use in the study of the performance of and possible improvements in existing designs. Working rules are given by which the data contained in the report may be used, and the most obvious conclusions as to the behavior of cores are summarized. Part 2 presents the results of tests made to determine the pressure necessary to produce water flows up to 50 gallons per minute through an 8-inch square section of radiator core. These data are of special value in evaluating the hydraulic head against which the circulating pump is required to operate.

Automatic Between-Pulse Analysis of DIII-D Experimental Data Performed Remotely on a Supercomputer at Argonne Leadership Computing Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kostuk, M.; Uram, T. D.; Evans, T.

For the first time, an automatically triggered, between-pulse fusion science analysis code was run on-demand at a remotely located supercomputer at Argonne Leadership Computing Facility (ALCF, Lemont, IL) in support of in-process experiments being performed at DIII-D (San Diego, CA). This represents a new paradigm for combining geographically distant experimental and high performance computing (HPC) facilities to provide enhanced data analysis that is quickly available to researchers. Enhanced analysis improves the understanding of the current pulse, translating into a more efficient use of experimental resources, and to the quality of the resultant science. The analysis code used here, called SURFMN,more » calculates the magnetic structure of the plasma using Fourier transform. Increasing the number of Fourier components provides a more accurate determination of the stochastic boundary layer near the plasma edge by better resolving magnetic islands, but requires 26 minutes to complete using local DIII-D resources, putting it well outside the useful time range for between pulse analysis. These islands relate to confinement and edge localized mode (ELM) suppression, and may be controlled by adjusting coil currents for the next pulse. Argonne has ensured on-demand execution of SURFMN by providing a reserved queue, a specialized service that launches the code after receiving an automatic trigger, and with network access from the worker nodes for data transfer. Runs are executed on 252 cores of ALCF’s Cooley cluster and the data is available locally at DIII-D within three minutes of triggering. The original SURFMN design limits additional improvements with more cores, however our work shows a path forward where codes that benefit from thousands of processors can run between pulses.« less

Automatic Between-Pulse Analysis of DIII-D Experimental Data Performed Remotely on a Supercomputer at Argonne Leadership Computing Facility

DOE PAGES

Kostuk, M.; Uram, T. D.; Evans, T.; ...

2018-02-01

For the first time, an automatically triggered, between-pulse fusion science analysis code was run on-demand at a remotely located supercomputer at Argonne Leadership Computing Facility (ALCF, Lemont, IL) in support of in-process experiments being performed at DIII-D (San Diego, CA). This represents a new paradigm for combining geographically distant experimental and high performance computing (HPC) facilities to provide enhanced data analysis that is quickly available to researchers. Enhanced analysis improves the understanding of the current pulse, translating into a more efficient use of experimental resources, and to the quality of the resultant science. The analysis code used here, called SURFMN,more » calculates the magnetic structure of the plasma using Fourier transform. Increasing the number of Fourier components provides a more accurate determination of the stochastic boundary layer near the plasma edge by better resolving magnetic islands, but requires 26 minutes to complete using local DIII-D resources, putting it well outside the useful time range for between pulse analysis. These islands relate to confinement and edge localized mode (ELM) suppression, and may be controlled by adjusting coil currents for the next pulse. Argonne has ensured on-demand execution of SURFMN by providing a reserved queue, a specialized service that launches the code after receiving an automatic trigger, and with network access from the worker nodes for data transfer. Runs are executed on 252 cores of ALCF’s Cooley cluster and the data is available locally at DIII-D within three minutes of triggering. The original SURFMN design limits additional improvements with more cores, however our work shows a path forward where codes that benefit from thousands of processors can run between pulses.« less

Parent education programmes for special health care needs children: a systematic review.

PubMed

Jackson, Alun C; Liang, Rachel P-T; Frydenberg, Erica; Higgins, Rosemary O; Murphy, Barbara M

2016-06-01

The aim of this review was to examine parent education programmes for families with children with special health care needs, to better design interventions focusing on the psychosocial aspects of living with a child's chronic condition. Studies of familial coping with children with special health care needs indicate high levels of parenting stress, with families with children with special health care needs at risk of major psychological and social disturbances and financial strain. Despite increased knowledge of the factors affecting children with special health care needs themselves, evidence for the effectiveness of preventative and treatment interventions in the form of parent education programmes remains limited. Systematic review using PRISMA guidelines. Multi database Boolean searches in EBSCO Discovery Services using the search terms 'complex/special health care needs children', 'child/pediatric/congenital heart disease', 'chronic illness (including diabetes, cancer and cystic fibrosis)', 'family coping', 'siblings' AND 'parenting/family support programs' were conducted. Analysis of 13 included studies showed evidence for the effectiveness of both mixed-health condition and condition-specific parenting programmes delivered in a variety of modes. Three common core intervention approaches were: use of narrative therapy enabling families to tell their own stories, thus facilitating emotional processing and (co-) construction of meaning; a focus on strengthening protective factors such as enhancing parents' skills in communication, and behavioural management and provision of psycho-education to deepen parents' understanding of their child's condition and associated developmental challenges. Irrespective of the type of outcome measures used in the studies, the review showed that there were positive gains and improvements across a range of areas of family functioning such as mental health, parenting, communication and problem-solving skills postprogramme. Identification of what programme characteristics enhance functioning for families with children with special health care needs should encourage the design of effective interventions. © 2016 John Wiley & Sons Ltd.

Transit Operations Decision Support System (TODSS) core requirements evaluation and update recommendations.

DOT National Transportation Integrated Search

2009-10-01

Transit Operations Decision Support Systems (TODSS) are systems designed to support dispatchers and others in real-time operations : management in response to incidents, special events, and other changing conditions in order to improve operating spee...

Primary Care-Mental Health Integration in the Veterans Affairs Health System: Program Characteristics and Performance.

PubMed

Cornwell, Brittany L; Brockmann, Laurie M; Lasky, Elaine C; Mach, Jennifer; McCarthy, John F

2018-06-01

The Veterans Health Administration (VHA) has achieved substantial national implementation of primary care-mental health integration (PC-MHI) services. However, little is known regarding program characteristics, variation in characteristics across settings, or associations between program fidelity and performance. This study identified core elements of PC-MHI services and evaluated their associations with program characteristics and performance. A principal-components analysis (PCA) of reports from 349 sites identified factors associated with PC-MHI fidelity. Analyses assessed the correlation among factors and between each factor and facility type (medical center or community-based outpatient clinic), primary care population size, and performance indicators (receipt of PC-MHI services, same-day access to mental health and primary care services, and extended duration of services). PCA identified seven factors: core implementation, care management (CM) assessments and supervision, CM supervision receipt, colocated collaborative care (CCC) by prescribing providers, CCC by behavioral health providers, participation in patient aligned care teams (PACTs) for special populations, and treatment of complex mental health conditions. Sites serving larger populations had greater core implementation scores. Medical centers and sites serving larger populations had greater scores for CCC by prescribing providers, CM assessments and supervision, and participation in PACTs. Greater core implementation scores were associated with greater same-day access. Sites with greater scores for CM assessments and supervision had lower scores for treatment of complex conditions. Outpatient clinics and sites serving smaller populations experienced challenges in integrated care implementation. To enhance same-day access, VHA should continue to prioritize PC-MHI implementation. Providing brief, problem-focused care may enhance CM implementation.

Scanning Our Future. A Report from the NGO Forum on the World Economic Order in Support of the Seventh Special Session of the UN General Assembly on Development and International Economic Cooperation (September 1-12, 1975).

ERIC Educational Resources Information Center

Archer, Angus, Ed.

This report of the Seventh Special Session at the Conference of Non-Governmental Organizations (NGOs) presents an account of the Forum on World Economic Order. Its purpose is to gain public awareness of the issues debated. The core of this report is the unique exchange of over 50 opinions which provide a compendium of ideas and judgments in the…

Development of a Rapidly Deployable Special Operations Component Command (SOCC) Core Concept for the North Atlantic Treaty Organization (NATO) Special Operations Headquarters (NSHQ)

DTIC Science & Technology

2011-12-01

operating in their territory. NSHQ is a new and evolving organization, which was instructed to develop a rapidly deployable HQ. NSHQ receives its...single overarching concept, eliminating redundancy, and integrates new deployable operational C2 structures (notably NSHQ) agreed through the...of the command and control issue is the ability to communicate effectively both up and down the chain of command. With the new technologies

Feasibility Study of Supercritical Light Water Cooled Reactors for Electric Power Production, Nuclear Energy Research Initiative Project 2001-001, Westinghouse Electric Co. Grant Number: DE-FG07-02SF22533, Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Philip E. MacDonald

2005-01-01

The supercritical water-cooled reactor (SCWR) is one of the six reactor technologies selected for research and development under the Generation IV program. SCWRs are promising advanced nuclear systems because of their high thermal efficiency (i.e., about 45% versus about 33% efficiency for current Light Water Reactors [LWRs]) and considerable plant simplification. SCWRs are basically LWRs operating at higher pressure and temperatures with a direct once-through cycle. Operation above the critical pressure eliminates coolant boiling, so the coolant remains single-phase throughout the system. Thus, the need for a pressurizer, steam generators, steam separators, and dryers is eliminated. The main mission ofmore » the SCWR is generation of low-cost electricity. It is built upon two proven technologies: LWRs, which are the most commonly deployed power generating reactors in the world, and supercritical fossil-fired boilers, a large number of which are also in use around the world. The reference SCWR design for the U.S. program is a direct cycle system operating at 25.0 MPa, with core inlet and outlet temperatures of 280 and 500 C, respectively. The coolant density decreases from about 760 kg/m3 at the core inlet to about 90 kg/m3 at the core outlet. The inlet flow splits with about 10% of the inlet flow going down the space between the core barrel and the reactor pressure vessel (the downcomer) and about 90% of the inlet flow going to the plenum at the top of the rector pressure vessel, to then flow down through the core in special water rods to the inlet plenum. Here it mixes with the feedwater from the downcomer and flows upward to remove the heat in the fuel channels. This strategy is employed to provide good moderation at the top of the core. The coolant is heated to about 500 C and delivered to the turbine. The purpose of this NERI project was to assess the reference U.S. Generation IV SCWR design and explore alternatives to determine feasibility. The project was organized into three tasks: Task 1. Fuel-cycle Neutronic Analysis and Reactor Core Design Task 2. Fuel Cladding and Structural Material Corrosion and Stress Corrosion Cracking Task 3. Plant Engineering and Reactor Safety Analysis. moderator rods. materials.« less

Transmission in Optically Transparent Core Networks

NASA Astrophysics Data System (ADS)

Kilper, Dan; Jensen, Rich; Petermann, Klaus; Karasek, Miroslav

2007-03-01

Scope of Submission

• Optically transparent system design issues, transmission experiments, and field trials
• Optically transparent network architectures and topologies
• Dispersion management in reconfigurable and mesh systems
• Optically transparent network device and sub-system performance, design, characterization and control, including: amplifiers, transmitters, receivers, switches, add/drop multiplexers
• Transient and fault management
• Physical layer system control
• Monitoring and compensation to support transparency
• Wavelength routing and planning as they relate to physical layer transmission
• Hardware cost and configuration optimization for optically transparent networks

Controlled Synthesis of Pd/Pt Core Shell Nanoparticles Using Area-selective Atomic Layer Deposition

PubMed Central

Cao, Kun; Zhu, Qianqian; Shan, Bin; Chen, Rong

2015-01-01

We report an atomic scale controllable synthesis of Pd/Pt core shell nanoparticles (NPs) via area-selective atomic layer deposition (ALD) on a modified surface. The method involves utilizing octadecyltrichlorosilane (ODTS) self-assembled monolayers (SAMs) to modify the surface. Take the usage of pinholes on SAMs as active sites for the initial core nucleation, and subsequent selective deposition of the second metal as the shell layer. Since new nucleation sites can be effectively blocked by surface ODTS SAMs in the second deposition stage, we demonstrate the successful growth of Pd/Pt and Pt/Pd NPs with uniform core shell structures and narrow size distribution. The size, shell thickness and composition of the NPs can be controlled precisely by varying the ALD cycles. Such core shell structures can be realized by using regular ALD recipes without special adjustment. This SAMs assisted area-selective ALD method of core shell structure fabrication greatly expands the applicability of ALD in fabricating novel structures and can be readily applied to the growth of NPs with other compositions. PMID:25683469

Multi-level slug tests in highly permeable formations: 2. Hydraulic conductivity identification, method verification, and field applications

USGS Publications Warehouse

Zlotnik, V.A.; McGuire, V.L.

1998-01-01

Using the developed theory and modified Springer-Gelhar (SG) model, an identification method is proposed for estimating hydraulic conductivity from multi-level slug tests. The computerized algorithm calculates hydraulic conductivity from both monotonic and oscillatory well responses obtained using a double-packer system. Field verification of the method was performed at a specially designed fully penetrating well of 0.1-m diameter with a 10-m screen in a sand and gravel alluvial aquifer (MSEA site, Shelton, Nebraska). During well installation, disturbed core samples were collected every 0.6 m using a split-spoon sampler. Vertical profiles of hydraulic conductivity were produced on the basis of grain-size analysis of the disturbed core samples. These results closely correlate with the vertical profile of horizontal hydraulic conductivity obtained by interpreting multi-level slug test responses using the modified SG model. The identification method was applied to interpret the response from 474 slug tests in 156 locations at the MSEA site. More than 60% of responses were oscillatory. The method produced a good match to experimental data for both oscillatory and monotonic responses using an automated curve matching procedure. The proposed method allowed us to drastically increase the efficiency of each well used for aquifer characterization and to process massive arrays of field data. Recommendations generalizing this experience to massive application of the proposed method are developed.Using the developed theory and modified Springer-Gelhar (SG) model, an identification method is proposed for estimating hydraulic conductivity from multi-level slug tests. The computerized algorithm calculates hydraulic conductivity from both monotonic and oscillatory well responses obtained using a double-packer system. Field verification of the method was performed at a specially designed fully penetrating well of 0.1-m diameter with a 10-m screen in a sand and gravel alluvial aquifer (MSEA site, Shelton, Nebraska). During well installation, disturbed core samples were collected every 0.6 m using a split-spoon sampler. Vertical profiles of hydraulic conductivity were produced on the basis of grain-size analysis of the disturbed core samples. These results closely correlate with the vertical profile of horizontal hydraulic conductivity obtained by interpreting multi-level slug test responses using the modified SG model. The identification method was applied to interpret the response from 474 slug tests in 156 locations at the MSEA site. More than 60% of responses were oscillatory. The method produced a good match to experimental data for both oscillatory and monotonic responses using an automated curve matching procedure. The proposed method allowed us to drastically increase the efficiency of each well used for aquifer characterization and to process massive arrays of field data. Recommendations generalizing this experience to massive application of the proposed method are developed.

The Kalanchoe genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, Xiaohan; Hu, Rongbin; Yin, Hengfu

Crassulacean acid metabolism (CAM) is a specialized photosynthetic adaptation to arid environments, found predominantly in diverse eudicotyledonous (eudicot) and monocotyledonous (monocot) lineages that diverged approximately 135 million years ago. To test whether convergent evolution underpins the independent emergences of CAM, we present de novo genome assembly and gene expression data for Kalanchoë fedtschenkoi, an obligate CAM species that was shown by multigene phylogenetic analysis to represent one of the earliest-diverging lineages of core eudicots. Our combined analysis of K. fedtschenkoi and two monocot CAM species (Ananas comosus and Phalaenopsis equestris) identified signatures of convergence in protein sequence and in themore » diel re-scheduling of genes involved in metabolism and signaling. Lastly, our results provide significant insight into CAM evolution, facilitating CAM-into-C 3 engineering for enhancing drought tolerance in crops.« less

The Kalanchoe genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism

DOE PAGES

Yang, Xiaohan; Hu, Rongbin; Yin, Hengfu; ...

2017-12-01

Crassulacean acid metabolism (CAM) is a specialized photosynthetic adaptation to arid environments, found predominantly in diverse eudicotyledonous (eudicot) and monocotyledonous (monocot) lineages that diverged approximately 135 million years ago. To test whether convergent evolution underpins the independent emergences of CAM, we present de novo genome assembly and gene expression data for Kalanchoë fedtschenkoi, an obligate CAM species that was shown by multigene phylogenetic analysis to represent one of the earliest-diverging lineages of core eudicots. Our combined analysis of K. fedtschenkoi and two monocot CAM species (Ananas comosus and Phalaenopsis equestris) identified signatures of convergence in protein sequence and in themore » diel re-scheduling of genes involved in metabolism and signaling. Lastly, our results provide significant insight into CAM evolution, facilitating CAM-into-C 3 engineering for enhancing drought tolerance in crops.« less

Core dynamics and the nutations of the Earth.

NASA Astrophysics Data System (ADS)

Dehant, V. M. A.; Laguerre, R.; Rekier, J.; Rivoldini, A.; Trinh, A.; Triana, A. S.; Van Hoolst, T.; Zhu, P.

2016-12-01

We here present an overview of the recent activities within the project RotaNut - Rotation and Nutation of a Wobbly Earth, an ERC Advanced Grant funding from the European Research Council. We have recomputed the Basic Earth Parameters from recent VLBI series and we interpret them in terms of physics of the Earth's deep interior. This includes updates of the nutational constraints on Earth's internal magnetic field and inner core viscosity, as well as of the coupling constants at the core-mantle boundary (CMB) and inner core boundary ICB. We have explored on simplified Earth models the interactions between rotational and gravito-inertial modes. With the help of numerical simulations, we have also addressed the coupling between the global rotation and the inertial waves in the fluid core through parametric instabilities. Special interests have been given to the influence of the inner core onto the stability properties of the liquid core and the large scale formation in the turbulent flow through inverse cascade of energy. The role of precession and nutation forcing for the liquid core is characterized as well as the interaction between the Free Core Nutation (in the fluid core community called the tilt-over mode) and the inertial waves. This research represents the first steps in the project RotaNut financed by the European Research Council under ERC Advanced Grant 670874 for 2015-2020.

Site characterization design and techniques used at the Southern Shipbuilding Corporation site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mueller, J.P.; Geraghty, C.A.; Moore, G.W.

1995-12-31

The Southern Shipbuilding Corporation (SSC) site is an inactive barge/ship manufacturing and repair facility situated on approximately 54 acres in Slidell, St. Tammany Parish, Louisiana. Two unlined surface impoundments (North and South impoundments) are situated on the northwest portion of the site and are surrounded on three sides by Bayou Bonfouca. These impoundments are the sources of carcinogenic polynuclear aromatic hydrocarbon (CPAH) contamination at the site. Inadequate containment has resulted in the release of impoundment wastes into the bayou. To evaluate potential response alternatives for the site, an Engineering Evaluation/Cost Analysis (EE/CA) field investigation was conducted from July through Octobermore » 1994. A two phase sampling approach was used in combination with innovative and traditional sampling techniques, field screening technologies, and exploitation of the visual characteristics of the waste to determine the extent of waste migration with limited off-site laboratory confirmation. A skid-mounted mobile drilling unit, secured to a specialized sampling platform designed for multiple applications, was used for collection of sediment cores from the bayou as well as tarry sludge cores from the impoundments. Field screening of core samples was accomplished on site using an organic vapor analyzer and a total petroleum hydrocarbon (TPH) field analyzer. Pollutants of concern include metals, cyanide, dioxin, and organic compounds. This paper presents details on the sampling design and characterization techniques used to accomplish the EE/CA field investigation.« less

Non-Abelian statistics of vortices with non-Abelian Dirac fermions.

PubMed

Yasui, Shigehiro; Hirono, Yuji; Itakura, Kazunori; Nitta, Muneto

2013-05-01

We extend our previous analysis on the exchange statistics of vortices having a single Dirac fermion trapped in each core to the case where vortices trap two Dirac fermions with U(2) symmetry. Such a system of vortices with non-Abelian Dirac fermions appears in color superconductors at extremely high densities and in supersymmetric QCD. We show that the exchange of two vortices having doublet Dirac fermions in each core is expressed by non-Abelian representations of a braid group, which is explicitly verified in the matrix representation of the exchange operators when the number of vortices is up to four. We find that the result contains the matrices previously obtained for the vortices with a single Dirac fermion in each core as a special case. The whole braid group does not immediately imply non-Abelian statistics of identical particles because it also contains exchanges between vortices with different numbers of Dirac fermions. However, we find that it does contain, as its subgroup, genuine non-Abelian statistics for the exchange of the identical particles, that is, vortices with the same number of Dirac fermions. This result is surprising compared with conventional understanding because all Dirac fermions are defined locally at each vortex, unlike the case of Majorana fermions for which Dirac fermions are defined nonlocally by Majorana fermions located at two spatially separated vortices.

Abnormal functional lateralization and activity of language brain areas in typical specific language impairment (developmental dysphasia)

PubMed Central

De Guibert, Clément; Maumet, Camille; Jannin, Pierre; Ferré, Jean-Christophe; Tréguier, Catherine; Barillot, Christian; Le Rumeur, Elisabeth; Allaire, Catherine; Biraben, Arnaud

2011-01-01

Atypical functional lateralization and specialization for language have been proposed to account for developmental language disorders, yet results from functional neuroimaging studies are sparse and inconsistent. This functional magnetic resonance imaging study compared children with a specific subtype of specific language impairment affecting structural language (n=21), to a matched group of typically-developing children using a panel of four language tasks neither requiring reading nor metalinguistic skills, including two auditory lexico-semantic tasks (category fluency and responsive naming) and two visual phonological tasks based on picture naming. Data processing involved normalizing the data with respect to a matched pairs pediatric template, groups and between-groups analysis, and laterality indexes assessment within regions of interest using single and combined task analysis. Children with specific language impairment exhibited a significant lack of left lateralization in all core language regions (inferior frontal gyrus-opercularis, inferior frontal gyrus-triangularis, supramarginal gyrus, superior temporal gyrus), across single or combined task analysis, but no difference of lateralization for the rest of the brain. Between-group comparisons revealed a left hypoactivation of Wernicke’s area at the posterior superior temporal/supramarginal junction during the responsive naming task, and a right hyperactivation encompassing the anterior insula with adjacent inferior frontal gyrus and the head of the caudate nucleus during the first phonological task. This study thus provides evidence that this specific subtype of specific language impairment is associated with atypical lateralization and functioning of core language areas. PMID:21719430

Facile preparation of gold nanocages and hollow gold nanospheres via solvent thermal treatment and their surface plasmon resonance and photothermal properties.

PubMed

Wang, Haifei; Han, Jing; Lu, Wensheng; Zhang, Jianping; Li, Jinru; Jiang, Long

2015-02-15

Although template etching method is one of the most common ways of preparation of hollow gold nanostructures, this approach still requires further improvements to avoid the collapse of gold shells after the cores were removed. In this work, an improved template etching method, with which hollow gold nanostructure is fabricated by etching Polystyrene (PS) cores from PS@Au core-shell nanospheres with solvent thermal treatment in N,N-Dimethylformamide (DMF), is demonstrated. When PS cores were removed by a thermal treatment process, gold nanoshells reconstruct and the collapse of the nanoshells is avoided. Gold nanocages and hollow gold nanospheres are easily obtained from the various structures of PS@Au core-shell nanospheres. These hollow nanostructures represent special near infrared (NIR) optical property and photothermal property. Compared with hollow gold nanospheres, the gold nanocages show higher temperature increase at the same particle concentration. Copyright © 2014 Elsevier Inc. All rights reserved.

Development code for sensitivity and uncertainty analysis of input on the MCNPX for neutronic calculation in PWR core

NASA Astrophysics Data System (ADS)

Hartini, Entin; Andiwijayakusuma, Dinan

2014-09-01

This research was carried out on the development of code for uncertainty analysis is based on a statistical approach for assessing the uncertainty input parameters. In the butn-up calculation of fuel, uncertainty analysis performed for input parameters fuel density, coolant density and fuel temperature. This calculation is performed during irradiation using Monte Carlo N-Particle Transport. The Uncertainty method based on the probabilities density function. Development code is made in python script to do coupling with MCNPX for criticality and burn-up calculations. Simulation is done by modeling the geometry of PWR terrace, with MCNPX on the power 54 MW with fuel type UO2 pellets. The calculation is done by using the data library continuous energy cross-sections ENDF / B-VI. MCNPX requires nuclear data in ACE format. Development of interfaces for obtaining nuclear data in the form of ACE format of ENDF through special process NJOY calculation to temperature changes in a certain range.

Operation of the WWR-S Reactor in Poland and in the Period 1961-1962; DOKLAD OB ISPOL'ZOVANII I EKSPLUATATSII REAKTORA TIPA VVR-C V POL'SHE ZA 1961-1962 GODA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aleksandrowicz, J.

1963-03-01

The experimental equipment used in the work at the horizontal reactor channels is listed. Diagrams of the utilization of the nominal reactor power and core loading are given, the reactivity fractions of the separate fuel assemblies are detonated, together with the diagram of reactivity versus burnup. Reactor channels and space used for sample irradiation and isotope production are described, and the total number of irradiations is given. Results of the measurements connected with the routine reactor operation are quoted, namely: analysis of water purity in the primary circuit, analysis of the work of the ion exchanger and mechanical filter, andmore » analysis of air activity in the special ventilation system. Data are given concerning radiation protection of personnel, including individual monitoring. Leak testing of the fuel elements is discussed. Damage of the reactor equipment and appearance of alarm signals are described. (auth)« less

Development code for sensitivity and uncertainty analysis of input on the MCNPX for neutronic calculation in PWR core

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hartini, Entin, E-mail: entin@batan.go.id; Andiwijayakusuma, Dinan, E-mail: entin@batan.go.id

2014-09-30

This research was carried out on the development of code for uncertainty analysis is based on a statistical approach for assessing the uncertainty input parameters. In the butn-up calculation of fuel, uncertainty analysis performed for input parameters fuel density, coolant density and fuel temperature. This calculation is performed during irradiation using Monte Carlo N-Particle Transport. The Uncertainty method based on the probabilities density function. Development code is made in python script to do coupling with MCNPX for criticality and burn-up calculations. Simulation is done by modeling the geometry of PWR terrace, with MCNPX on the power 54 MW with fuelmore » type UO2 pellets. The calculation is done by using the data library continuous energy cross-sections ENDF / B-VI. MCNPX requires nuclear data in ACE format. Development of interfaces for obtaining nuclear data in the form of ACE format of ENDF through special process NJOY calculation to temperature changes in a certain range.« less

Pathview Web: user friendly pathway visualization and data integration

PubMed Central

Pant, Gaurav; Bhavnasi, Yeshvant K.; Blanchard, Steven G.; Brouwer, Cory

2017-01-01

Abstract Pathway analysis is widely used in omics studies. Pathway-based data integration and visualization is a critical component of the analysis. To address this need, we recently developed a novel R package called Pathview. Pathview maps, integrates and renders a large variety of biological data onto molecular pathway graphs. Here we developed the Pathview Web server, as to make pathway visualization and data integration accessible to all scientists, including those without the special computing skills or resources. Pathview Web features an intuitive graphical web interface and a user centered design. The server not only expands the core functions of Pathview, but also provides many useful features not available in the offline R package. Importantly, the server presents a comprehensive workflow for both regular and integrated pathway analysis of multiple omics data. In addition, the server also provides a RESTful API for programmatic access and conveniently integration in third-party software or workflows. Pathview Web is openly and freely accessible at https://pathview.uncc.edu/. PMID:28482075

Low-Power Embedded DSP Core for Communication Systems

NASA Astrophysics Data System (ADS)

Tsao, Ya-Lan; Chen, Wei-Hao; Tan, Ming Hsuan; Lin, Maw-Ching; Jou, Shyh-Jye

2003-12-01

This paper proposes a parameterized digital signal processor (DSP) core for an embedded digital signal processing system designed to achieve demodulation/synchronization with better performance and flexibility. The features of this DSP core include parameterized data path, dual MAC unit, subword MAC, and optional function-specific blocks for accelerating communication system modulation operations. This DSP core also has a low-power structure, which includes the gray-code addressing mode, pipeline sharing, and advanced hardware looping. Users can select the parameters and special functional blocks based on the character of their applications and then generating a DSP core. The DSP core has been implemented via a cell-based design method using a synthesizable Verilog code with TSMC 0.35[InlineEquation not available: see fulltext.]m SPQM and 0.25[InlineEquation not available: see fulltext.]m 1P5M library. The equivalent gate count of the core area without memory is approximately 50 k. Moreover, the maximum operating frequency of a[InlineEquation not available: see fulltext.] version is 100 MHz (0.35[InlineEquation not available: see fulltext.]m) and 140 MHz (0.25[InlineEquation not available: see fulltext.]m).

Tank 241-AY-101 Privatization Push Mode Core Sampling and Analysis Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

TEMPLETON, A.M.

2000-01-12

This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for samples obtained from tank 241-AY-101. The purpose of this sampling event is to obtain information about the characteristics of the contents of 241-AY-101 required to satisfy Data Quality Objectives For RPP Privatization Phase I: Confirm Tank T Is An Appropriate Feed Source For High-Level Waste Feed Batch X(HLW DQO) (Nguyen 1999a), Data Quality Objectives For TWRS Privatization Phase I : Confirm Tank T Is An Appropriate Feed Source For Low-Activity Waste Feed Batch X (LAW DQO) (Nguyen 1999b), Low Activitymore » Waste and High-Level Waste Feed Data Quality Objectives (L and H DQO) (Patello et al. 1999), and Characterization Data Needs for Development, Design, and Operation of Retrieval Equipment Developed through the Data Quality Objective Process (Equipment DQO) (Bloom 1996). Special instructions regarding support to the LAW and HLW DQOs are provided by Baldwin (1999). Push mode core samples will be obtained from risers 15G and 150 to provide sufficient material for the chemical analyses and tests required to satisfy these data quality objectives. The 222-S Laboratory will extrude core samples; composite the liquids and solids; perform chemical analyses on composite and segment samples; archive half-segment samples; and provide subsamples to the Process Chemistry Laboratory. The Process Chemistry Laboratory will prepare test plans and perform process tests to evaluate the behavior of the 241-AY-101 waste undergoing the retrieval and treatment scenarios defined in the applicable DQOs. Requirements for analyses of samples originating in the process tests will be documented in the corresponding test plans and are not within the scope of this SAP.« less

Tank 241-AY-101 Privatization Push Mode Core Sampling and Analysis Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

TEMPLETON, A.M.

2000-05-19

This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for samples obtained from tank 241-AY-101. The purpose of this sampling event is to obtain information about the characteristics of the contents of 241-AY-101 required to satisfy ''Data Quality Objectives For RPP Privatization Phase I: Confirm Tank T Is An Appropriate Feed Source For High-Level Waste Feed Batch X(HLW DQO)' (Nguyen 1999a), ''Data Quality Objectives For TWRS Privatization Phase I: Confirm Tank T Is An Appropriate Feed Source For Low-Activity Waste Feed Butch X (LAW DQO) (Nguyen 1999b)'', ''Low Activity Wastemore » and High-Level Waste Feed Data Quality Objectives (L&H DQO)'' (Patello et al. 1999), and ''Characterization Data Needs for Development, Design, and Operation of Retrieval Equipment Developed through the Data Quality Objective Process (Equipment DQO)'' (Bloom 1996). Special instructions regarding support to the LAW and HLW DQOs are provided by Baldwin (1999). Push mode core samples will be obtained from risers 15G and 150 to provide sufficient material for the chemical analyses and tests required to satisfy these data quality objectives. The 222-S Laboratory will extrude core samples; composite the liquids and solids; perform chemical analyses on composite and segment samples; archive half-segment samples; and provide sub-samples to the Process Chemistry Laboratory. The Process Chemistry Laboratory will prepare test plans and perform process tests to evaluate the behavior of the 241-AY-101 waste undergoing the retrieval and treatment scenarios defined in the applicable DQOs. Requirements for analyses of samples originating in the process tests will be documented in the corresponding test plans and are not within the scope of this SAP.« less

Magnetic spherical cores partly coated with periodic mesoporous organosilica single crystals.

PubMed

Li, Jing; Wei, Yong; Li, Wei; Deng, Yonghui; Zhao, Dongyuan

2012-03-07

Core-shell structured materials are of special significance in various applications. Until now, most reported core-shell structures have polycrystalline or amorphous coatings as their shell layers, with popular morphologies of microspheres or quasi-spheres. However, the single crystals, either mesoscale or atomic ones, are still rarely reported as shell layers. If single crystals can be coated on core materials, it would result in a range of new type core-shell structures with various morphologies, and probably more potential applications. In this work, we demonstrate that periodic mesoporous organosilica (PMO) single crystals can partly grow on magnetic microspheres to form incomplete Fe(3)O(4)@nSiO(2)@PMO core-shell materials in aqueous solution, which indeed is the first illustration that mesoporous single-crystal materials can be used as shell layers for preparation of core-shell materials. The achieved materials have advantages of high specific surface areas, good magnetic responses, embedded functional groups and cubic mesopore channels, which might provide them with various application conveniences. We suppose the partial growth is largely decided by the competition between growing tendency of single crystals and the resistances to this tendency. In principle, other single crystals, including a range of atomic single crystals, such as zeolites, are able to be developed into such core-shell structures.

Food inflation in South Africa: some implications for economic policy.

PubMed

Rangasamy, Logan

2011-01-01

This paper analyses the trends in food price movements in South Africa between 1980 and 2008. There are three main results emanating from the analysis in this paper. Firstly, food price movements have played a large role in generating inflationary episodes in South Africa. Secondly, while external influences do matter, South African food price movements are mainly due to domestic influences. This implies that national policy has an important role to play in taming domestic food price inflation. Thirdly, given the strong second round impacts, food price movements warrant special attention in monetary policymaking. Core measures of inflation that exclude food price movements may not accurately reflect the underlying inflationary pressures in the economy and could compromise the attainment of the goal of price stability.

MSAViewer: interactive JavaScript visualization of multiple sequence alignments.

PubMed

Yachdav, Guy; Wilzbach, Sebastian; Rauscher, Benedikt; Sheridan, Robert; Sillitoe, Ian; Procter, James; Lewis, Suzanna E; Rost, Burkhard; Goldberg, Tatyana

2016-11-15

The MSAViewer is a quick and easy visualization and analysis JavaScript component for Multiple Sequence Alignment data of any size. Core features include interactive navigation through the alignment, application of popular color schemes, sorting, selecting and filtering. The MSAViewer is 'web ready': written entirely in JavaScript, compatible with modern web browsers and does not require any specialized software. The MSAViewer is part of the BioJS collection of components. The MSAViewer is released as open source software under the Boost Software License 1.0. Documentation, source code and the viewer are available at http://msa.biojs.net/Supplementary information: Supplementary data are available at Bioinformatics online. msa@bio.sh. © The Author 2016. Published by Oxford University Press.

MSAViewer: interactive JavaScript visualization of multiple sequence alignments

PubMed Central

Yachdav, Guy; Wilzbach, Sebastian; Rauscher, Benedikt; Sheridan, Robert; Sillitoe, Ian; Procter, James; Lewis, Suzanna E.; Rost, Burkhard; Goldberg, Tatyana

2016-01-01

Summary: The MSAViewer is a quick and easy visualization and analysis JavaScript component for Multiple Sequence Alignment data of any size. Core features include interactive navigation through the alignment, application of popular color schemes, sorting, selecting and filtering. The MSAViewer is ‘web ready’: written entirely in JavaScript, compatible with modern web browsers and does not require any specialized software. The MSAViewer is part of the BioJS collection of components. Availability and Implementation: The MSAViewer is released as open source software under the Boost Software License 1.0. Documentation, source code and the viewer are available at http://msa.biojs.net/. Supplementary information: Supplementary data are available at Bioinformatics online. Contact: msa@bio.sh PMID:27412096

Earthquake Resilient Tall Reinforced Concrete Buildings at Near-Fault Sites Using Base Isolation and Rocking Core Walls

NASA Astrophysics Data System (ADS)

Calugaru, Vladimir

This dissertation pursues three main objectives: (1) to investigate the seismic response of tall reinforced concrete core wall buildings, designed following current building codes, subjected to pulse type near-fault ground motion, with special focus on the relation between the characteristics of the ground motion and the higher-modes of response; (2) to determine the characteristics of a base isolation system that results in nominally elastic response of the superstructure of a tall reinforced concrete core wall building at the maximum considered earthquake level of shaking; and (3) to demonstrate that the seismic performance, cost, and constructability of a base-isolated tall reinforced concrete core wall building can be significantly improved by incorporating a rocking core-wall in the design. First, this dissertation investigates the seismic response of tall cantilever wall buildings subjected to pulse type ground motion, with special focus on the relation between the characteristics of ground motion and the higher-modes of response. Buildings 10, 20, and 40 stories high were designed such that inelastic deformation was concentrated at a single flexural plastic hinge at their base. Using nonlinear response history analysis, the buildings were subjected to near-fault seismic ground motions as well as simple close-form pulses, which represented distinct pulses within the ground motions. Euler-Bernoulli beam models with lumped mass and lumped plasticity were used to model the buildings. Next, this dissertation investigates numerically the seismic response of six seismically base-isolated (BI) 20-story reinforced concrete buildings and compares their response to that of a fixed-base (FB) building with a similar structural system above ground. Located in Berkeley, California, 2 km from the Hayward fault, the buildings are designed with a core wall that provides most of the lateral force resistance above ground. For the BI buildings, the following are investigated: two isolation systems (both implemented below a three-story basement), isolation periods equal to 4, 5, and 6 s, and two levels of flexural strength of the wall. The first isolation system combines tension-resistant friction pendulum bearings and nonlinear fluid viscous dampers (NFVDs); the second combines low-friction tension-resistant cross-linear bearings, lead-rubber bearings, and NFVDs. Finally, this dissertation investigates the seismic response of four 20-story buildings hypothetically located in the San Francisco Bay Area, 0.5 km from the San Andreas fault. One of the four studied buildings is fixed-base (FB), two are base-isolated (BI), and one uses a combination of base isolation and a rocking core wall (BIRW). Above the ground level, a reinforced concrete core wall provides the majority of the lateral force resistance in all four buildings. The FB and BI buildings satisfy requirements of ASCE 7-10. The BI and BIRW buildings use the same isolation system, which combines tension-resistant friction pendulum bearings and nonlinear fluid viscous dampers. The rocking core-wall includes post-tensioning steel, buckling-restrained devices, and at its base is encased in a steel shell to maximize confinement of the concrete core. The total amount of longitudinal steel in the wall of the BIRW building is 0.71 to 0.87 times that used in the BI buildings. Response history two-dimensional analysis is performed, including the vertical components of excitation, for a set of ground motions scaled to the design earthquake and to the maximum considered earthquake (MCE). While the FB building at MCE level of shaking develops inelastic deformations and shear stresses in the wall that may correspond to irreparable damage, the BI and the BIRW buildings experience nominally elastic response of the wall, with floor accelerations and shear forces which are 0.36 to 0.55 times those experienced by the FB building. The response of the four buildings to two historical and two simulated near-fault ground motions is also studied, demonstrating that the BIRW building has the largest deformation capacity at the onset of structural damage. (Abstract shortened by UMI.).

Nuclear engine flow reactivity shim control

DOEpatents

Walsh, J.M.

1973-12-11

A nuclear engine control system is provided which automatically compensates for reactor reactivity uncertainties at the start of life and reactivity losses due to core corrosion during the reactor life in gas-cooled reactors. The coolant gas flow is varied automatically by means of specially provided control apparatus so that the reactor control drums maintain a predetermined steady state position throughout the reactor life. This permits the reactor to be designed for a constant drum position and results in a desirable, relatively flat temperature profile across the core. (Official Gazette)

Depositional history and inventories of polychlorinated biphenyls (PCBs) in sediment cores from an Antarctic Specially Managed Area (Admiralty Bay, King George Island).

PubMed

Combi, Tatiane; Martins, César C; Taniguchi, Satie; Leonel, Juliana; Lourenço, Rafael André; Montone, Rosalinda Carmela

2017-05-15

Temporal patterns, fluxes and inventories of polychlorinated biphenyls (PCBs) were assessed in nine sediment cores collected from selected areas of Admiralty Bay off the Antarctic Peninsula. Concentrations of total PCBs were low, but slightly higher in comparison to low-impacted, remote environments in the world, ranging from below the detection limit to 11.9ngg -1 in dry weight. PCB concentrations and inventories suggest a possible minor influence related to the nearby logistic activities, especially in the sediment core collected close to the Ferraz Station. Despite being the most remote and protected area on the planet, the Antarctic continent is no longer a pristine environment. Copyright © 2017 Elsevier Ltd. All rights reserved.

48 CFR 970.1707-2 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-10-01

... commercialization; (c) Maintain facility core competencies; (d) Enhance the science and technology capabilities at... REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Special Contracting Methods 970.1707-2 Purpose. The purpose... accomplishing goals that may otherwise be unattainable and to avoid the possible duplication of effort at...

Curriculum Design Issues in Developing a Doctor of Philosophy Program in Aeronology.

ERIC Educational Resources Information Center

Johnson, Jeffrey A.

1997-01-01

Aviation education institutions (75 of 105 surveyed) expressed their preferences for the elements of a Ph.D. program in aeronology (nonengineering aerospace/aeronautical sciences). A research/practitioner model, core curriculum, and second area of specialization were supported. (SK)

[Special cannulas for the puncture of implanted catheter port systems].

PubMed

Haindl, H; Müller, H

1989-04-01

The Huber-Point cannula is generally recommended for portal puncture. Two comparative studies are published that show no advantage in using Huber-point cannulas. This has been verified by technical investigations. A new type of non-coring cannula is described.

SYNOPSIS OF EMERGING PATHOGEN WORKSHOP PUBLICATION

EPA Science Inventory

This presentation will highlight the core principles and findings from the 2001 workshop, the proceedings of which were recently published in a special edition of Compost Science. It will also provide a historical, policy and regulatory framework to shed light on, and be...

Transit Operations Decision Support System (TODSS) core requirements prototype development case study and lessons learned.

DOT National Transportation Integrated Search

2010-02-01

Transit Operations Decision Support Systems (TODSS) are systems designed to support dispatchers and others in real-time operations : management in response to incidents, special events, and other changing conditions. As part of a joint Federal Transi...

Genomic analysis of the type VI secretion systems in Pseudomonas spp.: novel clusters and putative effectors uncovered.

PubMed

Barret, Matthieu; Egan, Frank; Fargier, Emilie; Morrissey, John P; O'Gara, Fergal

2011-06-01

Bacteria encode multiple protein secretion systems that are crucial for interaction with the environment and with hosts. In recent years, attention has focused on type VI secretion systems (T6SSs), which are specialized transporters widely encoded in Proteobacteria. The myriad of processes associated with these secretion systems could be explained by subclasses of T6SS, each involved in specialized functions. To assess diversity and predict function associated with different T6SSs, comparative genomic analysis of 34 Pseudomonas genomes was performed. This identified 70 T6SSs, with at least one locus in every strain, except for Pseudomonas stutzeri A1501. By comparing 11 core genes of the T6SS, it was possible to identify five main Pseudomonas phylogenetic clusters, with strains typically carrying T6SSs from more than one clade. In addition, most strains encode additional vgrG and hcp genes, which encode extracellular structural components of the secretion apparatus. Using a combination of phylogenetic and meta-analysis of transcriptome datasets it was possible to associate specific subsets of VgrG and Hcp proteins with each Pseudomonas T6SS clade. Moreover, a closer examination of the genomic context of vgrG genes in multiple strains highlights a number of additional genes associated with these regions. It is proposed that these genes may play a role in secretion or alternatively could be new T6S effectors.

Scribl: an HTML5 Canvas-based graphics library for visualizing genomic data over the web.

PubMed

Miller, Chase A; Anthony, Jon; Meyer, Michelle M; Marth, Gabor

2013-02-01

High-throughput biological research requires simultaneous visualization as well as analysis of genomic data, e.g. read alignments, variant calls and genomic annotations. Traditionally, such integrative analysis required desktop applications operating on locally stored data. Many current terabyte-size datasets generated by large public consortia projects, however, are already only feasibly stored at specialist genome analysis centers. As even small laboratories can afford very large datasets, local storage and analysis are becoming increasingly limiting, and it is likely that most such datasets will soon be stored remotely, e.g. in the cloud. These developments will require web-based tools that enable users to access, analyze and view vast remotely stored data with a level of sophistication and interactivity that approximates desktop applications. As rapidly dropping cost enables researchers to collect data intended to answer questions in very specialized contexts, developers must also provide software libraries that empower users to implement customized data analyses and data views for their particular application. Such specialized, yet lightweight, applications would empower scientists to better answer specific biological questions than possible with general-purpose genome browsers currently available. Using recent advances in core web technologies (HTML5), we developed Scribl, a flexible genomic visualization library specifically targeting coordinate-based data such as genomic features, DNA sequence and genetic variants. Scribl simplifies the development of sophisticated web-based graphical tools that approach the dynamism and interactivity of desktop applications. Software is freely available online at http://chmille4.github.com/Scribl/ and is implemented in JavaScript with all modern browsers supported.

Preface of the special issue: "Vertical coupling in the atmosphere-ionosphere system: Recent progress"

NASA Astrophysics Data System (ADS)

2018-06-01

This special issue of the Journal of Atmospheric and Solar-Terrestrial Physics comprises papers dealing with investigation of the coupling phenomena in the neutral Atmosphere-Ionosphere System of the Earth. The core of the special issue is formed by the recent results presented during the 6th IAGA/ICMA/SCOSTEP Workshop on the Vertical Coupling in the Neutral Atmosphere-Ionosphere System held in Taipei, Taiwan, July 2016. Workshops are organized with a substantial support of the scientific international bodies, such as the International Association of Geomagnetism and Aeronomy (IAGA), International Commission for the Middle Atmosphere (ICMA) and Committee on Solar-Terrestrial Physics (SCOSTEP). The special issue includes also recent results of other members of the aeronomic research community. Hence it represents the state-of-art knowledge in the associated research fields.

Proteomic analysis of laser capture microscopy purified myotendinous junction regions from muscle sections

PubMed Central

2014-01-01

The myotendinous junction is a specialized structure of the muscle fibre enriched in mechanosensing complexes, including costameric proteins and core elements of the z-disc. Here, laser capture microdissection was applied to purify membrane regions from the myotendinous junctions of mouse skeletal muscles, which were then processed for proteomic analysis. Sarcolemma sections from the longitudinal axis of the muscle fibre were used as control for the specificity of the junctional preparation. Gene ontology term analysis of the combined lists indicated a statistically significant enrichment in membrane-associated proteins. The myotendinous junction preparation contained previously uncharacterized proteins, a number of z-disc costameric ligands (e.g., actinins, capZ, αB cristallin, filamin C, cypher, calsarcin, desmin, FHL1, telethonin, nebulin, titin and an enigma-like protein) and other proposed players of sarcomeric stretch sensing and signalling, such as myotilin and the three myomesin homologs. A subset were confirmed by immunofluorescence analysis as enriched at the myotendinous junction, suggesting that laser capture microdissection from muscle sections is a valid approach to identify novel myotendinous junction players potentially involved in mechanotransduction pathways. PMID:25071420

Comparative evolutionary genomics of Corynebacterium with special reference to codon and amino acid usage diversities.

PubMed

Pal, Shilpee; Sarkar, Indrani; Roy, Ayan; Mohapatra, Pradeep K Das; Mondal, Keshab C; Sen, Arnab

2018-02-01

The present study has been aimed to the comparative analysis of high GC composition containing Corynebacterium genomes and their evolutionary study by exploring codon and amino acid usage patterns. Phylogenetic study by MLSA approach, indel analysis and BLAST matrix differentiated Corynebacterium species in pathogenic and non-pathogenic clusters. Correspondence analysis on synonymous codon usage reveals that, gene length, optimal codon frequencies and tRNA abundance affect the gene expression of Corynebacterium. Most of the optimal codons as well as translationally optimal codons are C ending i.e. RNY (R-purine, N-any nucleotide base, and Y-pyrimidine) and reveal translational selection pressure on codon bias of Corynebacterium. Amino acid usage is affected by hydrophobicity, aromaticity, protein energy cost, etc. Highly expressed genes followed the cost minimization hypothesis and are less diverged at their synonymous positions of codons. Functional analysis of core genes shows significant difference in pathogenic and non-pathogenic Corynebacterium. The study reveals close relationship between non-pathogenic and opportunistic pathogenic Corynebaterium as well as between molecular evolution and survival niches of the organism.

Integrated Marketing Communications: A New Master's Degree Concept.

ERIC Educational Resources Information Center

Caywood, Clarke; Ewing, Raymond

1991-01-01

Describes how separate graduate degree programs have been fused into an integrated marketing communications program at Northwestern University. Discusses the five-quarter program that includes a core of new marketing communications planning and management classes, professional specialization classes in corporate public relations, advertising, and…

78 FR 9403 - National Eye Institute; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Eye Institute... personal privacy. Name of Committee: National Eye Institute Special Emphasis Panel; NEI Core Grant (P30... Extramural Research, National Eye Institute, National Institutes of Health, 5635 Fishers Lane, Suite 1300...

77 FR 1707 - National Cancer Institute; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-11

... Special Emphasis Panel; Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts... Domestic Assistance Program Nos. 93.392, Cancer Construction; 93.393, Cancer Cause and Prevention Research; 93.394, Cancer Detection and Diagnosis Research; 93.395, Cancer Treatment Research; 93.396, Cancer...

77 FR 49450 - National Cancer Institute; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-16

... Committee: National Cancer Institute Special Emphasis Panel; Core Infrastructure and Methodological Research...; Small Grants for Behavioral Research in Cancer Control. Date: September 18-19, 2012.. Time: 9 a.m. to 12...., Scientific Review Officer, Research Programs Review Branch, Division of Extramural Activities, National...

76 FR 57748 - National Cancer Institute Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-16

... Cancer Institute Special Emphasis Panel; Core Infrastructure and Methodological Research for Cancer... Review Officer, Research Programs Review Branch, Division of Extramural Activities, National Cancer... Panel; Community Clinical Oncology Program Research Bases (U10). Date: November 9, 2011. Time: 8:30 a.m...

Mental Health and the Law.

ERIC Educational Resources Information Center

Weinstein, Henry C.

1982-01-01

Briefly reviews historical development of mental health and the law as a multidisciplinary field and considers variety of information seekers addressing certain topics of special importance. Pertinent information sources and services are outlined. Fifteen references and a recommended core library for fellowship programs in forensic psychiatry are…

Four New Course Competencies for Majors.

ERIC Educational Resources Information Center

Van Leuven, Jim

1999-01-01

Notes changes in the past decade in the field of public relations. Proposes four new required core competencies for all undergraduate public-relations majors in programs housed in journalism/mass-communication units. Articulates these regarding appropriate outcomes, pedagogies, and assessment methods. Notes special considerations for small,…

New Medicine for the U.S. Health Care System: Training Physicians for Structural Interventions.

PubMed

Hansen, Helena; Metzl, Jonathan M

2017-03-01

Structural competency provides a language and theoretical framework to promote institutional-level interventions by clinical practitioners working with community organizations, non-health-sector institutions, and policy makers. The special collection of articles on structural competency in this issue of Academic Medicine addresses the need to move from theory to an appraisal of core educational interventions that operationalize the goals of and foster structural competency. In this Commentary, the authors review the role of clinical practitioners in enhancing population-level health outcomes through collaborations with professionals in fields outside medicine, including the social sciences and law. They describe the core elements of structural competency in preclinical and clinical education, as illustrated by the articles of this special collection: perceiving the structural causes of patients' disease, envisioning structural interventions, and cultivating alliances with non-health-sector agencies that can implement structural interventions. Finally, the authors argue that preparing trainees to form partnerships will empower them to influence the social determinants of their patients' health and reduce health inequalities.

The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles

PubMed Central

Topalidou, Irini; Cattin-Ortolá, Jérôme; MacCoss, Michael J.

2016-01-01

The dense-core vesicle is a secretory organelle that mediates the regulated release of peptide hormones, growth factors, and biogenic amines. Dense-core vesicles originate from the trans-Golgi of neurons and neuroendocrine cells, but it is unclear how this specialized organelle is formed and acquires its specific cargos. To identify proteins that act in dense-core vesicle biogenesis, we performed a forward genetic screen in Caenorhabditis elegans for mutants defective in dense-core vesicle function. We previously reported the identification of two conserved proteins that interact with the small GTPase RAB-2 to control normal dense-core vesicle cargo-sorting. Here we identify several additional conserved factors important for dense-core vesicle cargo sorting: the WD40 domain protein EIPR-1 and the endosome-associated recycling protein (EARP) complex. By assaying behavior and the trafficking of dense-core vesicle cargos, we show that mutants that lack EIPR-1 or EARP have defects in dense-core vesicle cargo-sorting similar to those of mutants in the RAB-2 pathway. Genetic epistasis data indicate that RAB-2, EIPR-1 and EARP function in a common pathway. In addition, using a proteomic approach in rat insulinoma cells, we show that EIPR-1 physically interacts with the EARP complex. Our data suggest that EIPR-1 is a new interactor of the EARP complex and that dense-core vesicle cargo sorting depends on the EARP-dependent trafficking of cargo through an endosomal sorting compartment. PMID:27191843

Multi-Core Processor Memory Contention Benchmark Analysis Case Study

NASA Technical Reports Server (NTRS)

Simon, Tyler; McGalliard, James

2009-01-01

Multi-core processors dominate current mainframe, server, and high performance computing (HPC) systems. This paper provides synthetic kernel and natural benchmark results from an HPC system at the NASA Goddard Space Flight Center that illustrate the performance impacts of multi-core (dual- and quad-core) vs. single core processor systems. Analysis of processor design, application source code, and synthetic and natural test results all indicate that multi-core processors can suffer from significant memory subsystem contention compared to similar single-core processors.

Planktonic foraminifera as proxies of Upper Quaternary sedimentation in The Okhotsk sea

NASA Astrophysics Data System (ADS)

Romanova, Alexandra

2013-04-01

Analyzing planktonic foraminifera in marine sediments assists us in reconstructing historical maps of climatic changes. The object of the study is the Okhotsk Sea, largest Russian Far East sea. Okhotsk sea, like other marginal seas, is very sensitive to global and regional climate changes. Planktonic foraminifera are poorly investigated in Okhotsk sea. Studying of planktonic foraminifera in Okhotsk sea has some problems: low quantity of species, one taxon domination, low percents of another species, influence of dissolution. These facts don't allow us to use standard approaches for paleotemperature reconstructions using planktonic foraminifera. This research explores the response of this group of microorganisms to main paleoclimatic events in Okhotsk region and attempt to reveal the special characteristics of this proxy for interpreting the paleoodata. The research was based on samples from 4 cores in the central part of the sea and 67 sediment stations from north to south (total of about 270 samples). As a result of studying sediment stations we created a map of biogeographycal distribution of planktonic foraminifera and distinguished five provinces. Each province has specific quantitive and qualative characteristics of foraminifera assemblages that give us information about their modern distribution and ecological preferences. This information is necessary for comparison with cores data. By correlating data from other analysis (radiocarbon dating, benthic and planktonic δ18O records, geochemical, pollen, diatom analyses) with discovered foraminifera sample data (core 936), we established certain climatic patterns and defined 5 criteria to apply to all of the other cores that did not have the same depth of climate information. We find that variation in abundance of different morhpotypes allows determining period of cooling and warming, which is confirmed by the variation in abundance across all of foraminifera species. These criteria might be a solution for paleotemerature reconstruction using planktonic foraminifera.

Signatures of host specialization and a recent transposable element burst in the dynamic one-speed genome of the fungal barley powdery mildew pathogen.

PubMed

Frantzeskakis, Lamprinos; Kracher, Barbara; Kusch, Stefan; Yoshikawa-Maekawa, Makoto; Bauer, Saskia; Pedersen, Carsten; Spanu, Pietro D; Maekawa, Takaki; Schulze-Lefert, Paul; Panstruga, Ralph

2018-05-22

Powdery mildews are biotrophic pathogenic fungi infecting a number of economically important plants. The grass powdery mildew, Blumeria graminis, has become a model organism to study host specialization of obligate biotrophic fungal pathogens. We resolved the large-scale genomic architecture of B. graminis forma specialis hordei (Bgh) to explore the potential influence of its genome organization on the co-evolutionary process with its host plant, barley (Hordeum vulgare). The near-chromosome level assemblies of the Bgh reference isolate DH14 and one of the most diversified isolates, RACE1, enabled a comparative analysis of these haploid genomes, which are highly enriched with transposable elements (TEs). We found largely retained genome synteny and gene repertoires, yet detected copy number variation (CNV) of secretion signal peptide-containing protein-coding genes (SPs) and locally disrupted synteny blocks. Genes coding for sequence-related SPs are often locally clustered, but neither the SPs nor the TEs reside preferentially in genomic regions with unique features. Extended comparative analysis with different host-specific B. graminis formae speciales revealed the existence of a core suite of SPs, but also isolate-specific SP sets as well as congruence of SP CNV and phylogenetic relationship. We further detected evidence for a recent, lineage-specific expansion of TEs in the Bgh genome. The characteristics of the Bgh genome (largely retained synteny, CNV of SP genes, recently proliferated TEs and a lack of significant compartmentalization) are consistent with a "one-speed" genome that differs in its architecture and (co-)evolutionary pattern from the "two-speed" genomes reported for several other filamentous phytopathogens.

Blended-Wing-Body (BWB) Fuselage Structural Design for Weight Reduction

NASA Technical Reports Server (NTRS)

Mukhopadhyay, V.

2005-01-01

Structural analysis and design of efficient pressurized fuselage configurations for the advanced Blended-Wing-Body (BWB) flight vehicle is a challenging problem. Unlike a conventional cylindrical pressurized fuselage, stress level in a box type BWB fuselage is an order of magnitude higher, because internal pressure primarily results in bending stress instead of skin-membrane stress. In addition, resulting deformation of aerodynamic surface could significantly affect performance advantages provided by lifting body. The pressurized composite conformal multi-lobe tanks of X-33 type space vehicle also suffered from similar problem. In the earlier BWB design studies, Vaulted Ribbed Shell (VLRS), Flat Ribbed Shell (FRS); Vaulted shell Honeycomb Core (VLHC) and Flat sandwich shell Honeycomb Core (FLHC) concepts were studied. The flat and vaulted ribbed shell concepts were found most efficient. In a recent study, a set of composite sandwich panel and cross-ribbed panel were analyzed. Optimal values of rib and skin thickness, rib spacing, and panel depth were obtained for minimal weight under stress and buckling constraints. In addition, a set of efficient multi-bubble fuselage (MBF) configuration concept was developed. The special geometric configuration of this concept allows for balancing internal cabin pressure load efficiently, through membrane stress in inner-stiffened shell and inter-cabin walls, while the outer-ribbed shell prevents buckling due to external resultant compressive loads. The initial results from these approximate finite element analyses indicate progressively lower maximum stresses and deflections compared to the earlier study. However, a relative comparison of the FEM weight per unit floor area of the segment unit indicates that the unit weights are still relatively higher that the conventional B777 type cylindrical or A380 type elliptic fuselage design. Due to the manufacturing concern associated with multi-bubble fuselage, a Y braced box-type fuselage alternative with special resin-film injected (RFI) stitched carbon composite with foam-core was designed by Boeing under a NASA research contract for the 480 passenger version. It is shown that this configuration can be improved to a modified multi-bubble fuselage which has better stress distribution, for same material and dimension.

High permeability cores to optimize the stimulation of deeply located brain regions using transcranial magnetic stimulation

NASA Astrophysics Data System (ADS)

Salvador, R.; Miranda, P. C.; Roth, Y.; Zangen, A.

2009-05-01

Efficient stimulation of deeply located brain regions with transcranial magnetic stimulation (TMS) poses many challenges, arising from the fact that the induced field decays rapidly and becomes less focal with depth. We propose a new method to improve the efficiency of TMS of deep brain regions that combines high permeability cores, to increase focality and field intensity, with a coil specifically designed to induce a field that decays slowly with increasing depth. The performance of the proposed design was investigated using the finite element method to determine the total electric field induced by this coil/core arrangement on a realistically shaped homogeneous head model. The calculations show that the inclusion of the cores increases the field's magnitude by as much as 25% while also decreasing the field's decay with depth along specific directions. The focality, as measured by the area where the field's norm is greater than 1/\\sqrt 2 of its maximum value, is also improved by as much as 15% with some core arrangements. The coil's inductance is not significantly increased by the cores. These results show that the presence of the cores might make this specially designed coil even more suited for the effective stimulation of deep brain regions.

Enhancement of the sweep efficiency of waterflooding operations by the in-situ microbial population of petroleum reservoirs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, L.R.; Vadie, A.A.; Stephens, J.O.

1995-12-31

Live cores were obtained from five reservoirs using special precautions to prevent contamination by exogenous microorganisms and minimize exposure to oxygen. The depths from which the cores were obtained ranged from 2,705 ft to 6,568 ft. Core plugs were cut radially from live cores, encased in heat-shrink plastic tubes, placed in core holders, and fitted with inlets and outlets. Nutrient additions stimulated the in-situ microbial population to increase, dissolve stratal material, produce gases, and release oil. Reduction in flow through the core plugs was observed in some cases, while in other cases flow was increased, probably due to the dissolutionmore » of carbonates in the formation. A field demonstration of the ability of the in-situ microbial population to increase oil recovery by blocking the more permeable zones of the reservoir is currently underway. This demonstration is being conducted in the North Blowhorn Creek Unit situated in Lamar County, Alabama. Live cores were obtained from a newly drilled well in the field and tested as described above. The field project involves four test patterns each including one injector, four to five producers, and a comparable control injector with its four to five producers. Nutrient injection in the field began November 1994.« less

Research Library Issues: A Report from ARL, CNI, and SPARC. RLI 283

ERIC Educational Resources Information Center

Baughman, M. Sue, Ed.

2013-01-01

"Research Library Issues" ("RLI") focuses on current and emerging topics that are strategically important to research libraries. The articles explore issues, share information, pose critical questions, and provide examples. This issue includes the following articles: (1) Special at the Core: Aligning, Integrating, and…

76 FR 37358 - National Cancer Institute; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-27

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Cancer Institute... personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel, Core Infrastructure and Methological Research for Cancer Epidemiology Cohorts, Date: July 12, 2011, Time: 8 a,m, to 5 p,m...

What a Cognitivist Can Take from Discursive Research

ERIC Educational Resources Information Center

Brown, Margaret

2016-01-01

To an unreconstructed cognitivist with experience of developing General Certificate of Secondary Education (GCSE) examinations and national tests in mathematics, the three papers which provide the core of this special issue (Morgan & Sfard; Morgan, Morgan & Tang) provided a refreshing opportunity to consider examination items from a…

Combat Conditioning: The Need for Stronger Marines

DTIC Science & Technology

2008-02-18

shows how the average weight carried by warriors has increased over time. 3 “ CrossFit is a core strength and conditioning program...We have designed our program to elicit as broad an adaptational response as possible. CrossFit is not a specialized fitness program but a

Improvements in Fabrication of Sand/Binder Cores for Casting

NASA Technical Reports Server (NTRS)

Bakhitiyarov, Sayavur I.; Overfelt, Ruel A.; Adanur, Sabit

2005-01-01

Three improvements have been devised for the cold-box process, which is a special molding process used to make sand/binder cores for casting hollow metal parts. These improvements are: The use of fiber-reinforced composite binder materials (in contradistinction to the non-fiber-reinforced binders used heretofore), The substitution of a directed-vortex core-blowing subprocess for a prior core-blowing process that involved a movable gassing plate, and The use of filters made from filtration-grade fabrics to prevent clogging of vents. For reasons that exceed the scope of this article, most foundries have adopted the cold-box process for making cores for casting metals. However, this process is not widely known outside the metal-casting industry; therefore, a description of pertinent aspects of the cold-box process is prerequisite to a meaningful description of the aforementioned improvements. In the cold-box process as practiced heretofore, sand is first mixed with a phenolic resin (considered to be part 1 of a three-part binder) and an isocyanate resin (part 2 of the binder). Then by use of compressed air, the mixture is blown into a core box, which is a mold for forming the core. Next, an amine gas (part 3 of the binder) that acts as a catalyst for polymerization of parts 1 and 2 is blown through the core box. Alternatively, a liquid amine that vaporizes during polymerization can be incorporated into the sand/resin mixture. Once polymerization is complete, the amine gas is purged from the core box by use of compressed air. The finished core is then removed from the core box.

SPERT I DESTRUCTIVE TEST PROGRAM SAFETY ANALYSIS REPORT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spano, A.H.; Miller, R.W.

1962-06-15

The water-moderated core used for destructive experiments is mounted in the Spent I open-type reactor vessel, which has no provision for pressurization or forced coolant flow. The core is an array of highly enriched aluminum clad, plate-type fuel assemblies, using four bladetype, gang-operated control rods. Reactor transients are initiated at ambient temperature by step-insentions of reactivity, using a control rod which can be quickly ejected from the core. Following an initial series of static measurements to determine the basic- reactor properties of the test core, a series of nondestructive, self-limiting power excursion tests was performed, which covered a reactor periodmore » range down to the point where minor fuel plate damage first occurred -approximately for a 10- msec period test. These tests provided power, temperature, and pressure data. Additional kinetic teste in the period region between 10 and 5 msec were completed to explore the region of limited core damage. Fuel plate damage results included plate distortion, cladding cracking, and fuel melting. These exploratory tests were valuable in revealing unexpected changes in the dependence of pressure, temperature, burst energy, and burst shape parameters on reactor period, although the dependence of peak power on reactor period was not significantly changed. An evaluation of hazards involved in conducting the 2- msec test, based on pessimistic assumptions regarding fission product release and weather conditions, indicates that with the procedural controls normally exercised in the conduct of any transient test at Spent and the special controls to be in effect during the destructive test series, no significant hazard to personnel or to the general public will be obtained. All nuclear operation is conducted remotely approximately 1/2 mile from the reactor building. Discussion is also given of the supervision and control of personnel during and after each destructive test, and of the plans for re-entry, cleanup, and restoration of the facility. (auth)« less

Special nuclear material simulation device

DOEpatents

Leckey, John H.; DeMint, Amy; Gooch, Jack; Hawk, Todd; Pickett, Chris A.; Blessinger, Chris; York, Robbie L.

2014-08-12

An apparatus for simulating special nuclear material is provided. The apparatus typically contains a small quantity of special nuclear material (SNM) in a configuration that simulates a much larger quantity of SNM. Generally the apparatus includes a spherical shell that is formed from an alloy containing a small quantity of highly enriched uranium. Also typically provided is a core of depleted uranium. A spacer, typically aluminum, may be used to separate the depleted uranium from the shell of uranium alloy. A cladding, typically made of titanium, is provided to seal the source. Methods are provided to simulate SNM for testing radiation monitoring portals. Typically the methods use at least one primary SNM spectral line and exclude at least one secondary SNM spectral line.

Oral Health on Wheels: A Service Learning Project for Dental Hygiene Students.

PubMed

Flick, Heather; Barrett, Sheri; Carter-Hanson, Carrie

2016-08-01

To provide dental hygiene students with a service learning opportunity to work with special needs and culturally diverse underserved populations through the Oral Health on Wheels (OHOW) community based mobile dental hygiene clinic. A student feedback survey was administered between the years of 2009 and 2013 to 90 students in order to gather and identify significant satisfaction, skills acquisition and personal growth information after the student's clinical experience on the OHOW. ANOVA and Pearson correlation coefficient statistical analysis were utilized to investigate relationships between student responses to key questions in the survey. An analysis of 85 student responses (94.44%) demonstrated statistically significant correlations between student learning and their understanding of underserved populations, building confidence in skills, participation as a dental team member and understanding their role in total patient care. The strong correlations between these key questions related to the clinical experience and students confidence, skills integration into the dental team, and understanding of both total patient care, and the increased understanding of the oral health care needs of special populations. All questions directly link to the core mission of the OHOW program. The OHOW clinical experience allows dental hygiene students a unique opportunity to engage in their community while acquiring necessary clinical competencies required by national accreditation and providing access to oral health care services to underserved patients who would otherwise go without treatment. Copyright © 2016 The American Dental Hygienists’ Association.

Study on Mobile Object Positioning and Alarming System Based on the “Map World” in the Core Area of the Silk Road Economic Belt

NASA Astrophysics Data System (ADS)

Mu, Kai

2017-02-01

The established “Map World” on the National Geographic Information Public Service Platform offers free access to many geographic information in the Core Area of the Silk Road Economic Belt. Considering the special security situation and severe splittism and anti-splittism struggles in the Core Area of the Silk Road Economic Belt, a set of moving target positioning and alarming platform based on J2EE platform and B/S structure was designed and realized by combining the “Map World” data and global navigation satellite system. This platform solves various problems, such as effective combination of Global Navigation Satellite System (GNSS) and “Map World” resources, moving target alarming setting, inquiry of historical routes, system management, etc.

Stability of a Bifunctional Cu-Based Core@Zeolite Shell Catalyst for Dimethyl Ether Synthesis Under Redox Conditions Studied by Environmental Transmission Electron Microscopy and In Situ X-Ray Ptychography.

PubMed

Baier, Sina; Damsgaard, Christian D; Klumpp, Michael; Reinhardt, Juliane; Sheppard, Thomas; Balogh, Zoltan; Kasama, Takeshi; Benzi, Federico; Wagner, Jakob B; Schwieger, Wilhelm; Schroer, Christian G; Grunwaldt, Jan-Dierk

2017-06-01

When using bifunctional core@shell catalysts, the stability of both the shell and core-shell interface is crucial for catalytic applications. In the present study, we elucidate the stability of a CuO/ZnO/Al2O3@ZSM-5 core@shell material, used for one-stage synthesis of dimethyl ether from synthesis gas. The catalyst stability was studied in a hierarchical manner by complementary environmental transmission electron microscopy (ETEM), scanning electron microscopy (SEM) and in situ hard X-ray ptychography with a specially designed in situ cell. Both reductive activation and reoxidation were applied. The core-shell interface was found to be stable during reducing and oxidizing treatment at 250°C as observed by ETEM and in situ X-ray ptychography, although strong changes occurred in the core on a 10 nm scale due to the reduction of copper oxide to metallic copper particles. At 350°C, in situ X-ray ptychography indicated the occurrence of structural changes also on the µm scale, i.e. the core material and parts of the shell undergo restructuring. Nevertheless, the crucial core-shell interface required for full bifunctionality appeared to remain stable. This study demonstrates the potential of these correlative in situ microscopy techniques for hierarchically designed catalysts.

Candidate molten salt investigation for an accelerator driven subcritical core

NASA Astrophysics Data System (ADS)

Sooby, E.; Baty, A.; Beneš, O.; McIntyre, P.; Pogue, N.; Salanne, M.; Sattarov, A.

2013-09-01

We report a design for accelerator-driven subcritical fission in a molten salt core (ADSMS) that utilizes a fuel salt composed of NaCl and transuranic (TRU) chlorides. The ADSMS core is designed for fast neutronics (28% of neutrons >1 MeV) to optimize TRU destruction. The choice of a NaCl-based salt offers benefits for corrosion, operating temperature, and actinide solubility as compared with LiF-based fuel salts. A molecular dynamics (MD) code has been used to estimate properties of the molten salt system which are important for ADSMS design but have never been measured experimentally. Results from the MD studies are reported. Experimental measurements of fuel salt properties and studies of corrosion and radiation damage on candidate metals for the core vessel are anticipated. A special thanks is due to Prof. Paul Madden for introducing the ADSMS group to the concept of using the molten salt as the spallation target, rather than a conventional heavy metal spallation target. This feature helps to optimize this core as a Pu/TRU burner.

A core syllabus for the teaching of neuroanatomy to medical students.

PubMed

Moxham, Bernard; McHanwell, Stephen; Plaisant, Odile; Pais, Diogo

2015-09-01

There is increasingly a call for clinical relevance in the teaching of biomedical sciences within all health care courses. However, this presupposes that there is a clear understanding of what can be considered core material within the curricula. To date, the anatomical sciences have been relatively poorly served by the development of core syllabuses, particularly for specialized core syllabuses such as neuroanatomy. One of the aims of the International Federation of Associations of Anatomists (IFAA) and of the European Federation for Experimental Morphology (EFEM) is to formulate, on an international scale, core syllabuses for all branches of the anatomical sciences using Delphi Panels consisting of anatomists, scientists, and clinicians to initially evaluate syllabus content. In this article, the findings of a Delphi Panel for neuroanatomy are provided. These findings will subsequently be published on the IFAA website to enable anatomical (and other cognate learned) societies and individual anatomists, clinicians, and students to freely comment upon, and elaborate and amend, the syllabuses. The aim is to set internationally recognized standards and thus to provide guidelines concerning neuroanatomical knowledge when engaged in course development. © 2015 Wiley Periodicals, Inc.

Single Cell Synchrotron FT-IR Microspectroscopy Reveals a Link between Neutral Lipid and Storage Carbohydrate Fluxes in S. cerevisiae

PubMed Central

Jamme, Frédéric; Vindigni, Jean-David; Méchin, Valérie; Cherifi, Tamazight; Chardot, Thierry; Froissard, Marine

2013-01-01

In most organisms, storage lipids are packaged into specialized structures called lipid droplets. These contain a core of neutral lipids surrounded by a monolayer of phospholipids, and various proteins which vary depending on the species. Hydrophobic structural proteins stabilize the interface between the lipid core and aqueous cellular environment (perilipin family of proteins, apolipoproteins, oleosins). We developed a genetic approach using heterologous expression in Saccharomyces cerevisiae of the Arabidopsis thaliana lipid droplet oleosin and caleosin proteins AtOle1 and AtClo1. These transformed yeasts overaccumulate lipid droplets, leading to a specific increase in storage lipids. The phenotype of these cells was explored using synchrotron FT-IR microspectroscopy to investigate the dynamics of lipid storage and cellular carbon fluxes reflected as changes in spectral fingerprints. Multivariate statistical analysis of the data showed a clear effect on storage carbohydrates and more specifically, a decrease in glycogen in our modified strains. These observations were confirmed by biochemical quantification of the storage carbohydrates glycogen and trehalose. Our results demonstrate that neutral lipid and storage carbohydrate fluxes are tightly connected and co-regulated. PMID:24040242

New milarite/osumilite-type phase formed during ancient glazing of an Egyptian scarab

NASA Astrophysics Data System (ADS)

Artioli, G.; Angelini, I.; Nestola, F.

2013-02-01

A scarab found in grave 25 of the Monte Prama necropolis, near Cabras, Oristano, Sardinia, is of special importance for the archaeological interpretation and dating of this important archaeological site. The object has been misinterpreted in the past as composed by bone: recent archaeometric analyses showed that it is a glazed steatite of Egyptian origin and that the altered surface contains interesting phases crystallized during the high-temperature interaction of the Mg-rich talc core with the alkali-rich glass used for glazing. A novel single crystal X-ray diffraction analysis of one of the phases indicates that it is a new compound having the milarite-osumilite structure type, with a peculiar composition close to (Na1.52K0.12□0.36)(Mg3)(Mg1.72Cu0.16Fe0.12)(Si11.4Al0.6)O30, not reported for naturally occurring minerals. The structural and crystal chemical features of the compound, together with the known high-temperature stability of the series, allow a complete interpretation of the glazing process and conditions, based on direct application of the glaze on the steatite core with subsequent treatment at temperatures above 1000 °C.

Microevolution of aquatic Streptococcus agalactiae ST-261 from Australia indicates dissemination via imported tilapia and ongoing adaptation to marine hosts or environment.

PubMed

Kawasaki, Minami; Delamare-Deboutteville, Jerome; Bowater, Rachel O; Walker, Mark J; Beatson, Scott; Ben Zakour, Nouri L; Barnes, Andrew C

2018-06-18

Streptococcus agalactiae (GBS) causes disease in a wide range of animals. The serotype Ib lineage is highly adapted to aquatic hosts, exhibiting substantial genome reduction compared with terrestrial conspecifics. Here we sequence genomes from 40 GBS isolates including 25 from wild fish and captive stingrays in Australia, six local veterinary or human clinical isolates, and nine isolates from farmed tilapia in Honduras and compare with 42 genomes from public databases. Phylogenetic analysis based on non-recombinant core genome SNPs indicated that aquatic serotype Ib isolates from Queensland were distantly related to local veterinary and human clinical isolates. In contrast, Australian aquatic isolates are most closely related to a tilapia isolate from Israel, differing by only 63 core-genome SNPs. A consensus minimum spanning tree based on core genome SNPs indicates dissemination of ST-261 from an ancestral tilapia strain, which is congruent with several introductions of tilapia into Australia from Israel during the 1970s and 1980s. Pan-genome analysis identified 1,440 genes as core with the majority being dispensable or strain-specific with non-protein-coding intergenic regions (IGRs) divided amongst core and strain-specific genes. Aquatic serotype Ib strains have lost many virulence factors during adaptation, but six adhesins were well conserved across the aquatic isolates and might be critical for virulence in fish and targets for vaccine development. The close relationship amongst recent ST-261 isolates from Ghana, USA and China with the Israeli tilapia isolate from 1988 implicates the global trade in tilapia seed for aquaculture in the widespread dissemination of serotype Ib fish-adapted GBS. Importance Streptococcus agalactiae (GBS) is a significant pathogen of humans and animals. Some lineages have become adapted to particular hosts and serotype Ib is highly specialized to fish. Here we show that this lineage is likely to have been distributed widely by the global trade in tilapia for aquaculture, with probable introduction into Australia in the 1970s and subsequent dissemination in wild fish populations. We report variability in the polysaccharide capsule amongst this lineage, but identify a cohort of common surface proteins that may be a focus of future vaccine development to reduce the biosecurity risk in international fish trade. © Crown copyright 2018.

Magnetic field generation in the cores of terrestrial bodies

NASA Astrophysics Data System (ADS)

Runcorn, S. K.

Efforts to find some scaling law for the dipole moments of planets seem illusory for, although dynamo theory is still in a rudimentary state, once the critical magnetic Reynolds Number is exceeded it appears that the field strength is determined by the energy source, it it is permissible to treat the core as a heat engine. For this reason the lunar magnetic field is of special significance as the paleomagnetic evidence strongly suggests that the surface field was about 1 G 3.9 by diminishing exponentially to about .02 G 3.2 by ago and completely disappearing some time later.

Dating, synthesis, and interpretation of palaeoclimatic records of the Last Glacial cycle and model-data integration: advances by the INTIMATE (INTegration of Ice-core, MArine and TErrestrial records) COST Action ES0907

NASA Astrophysics Data System (ADS)

Rasmussen, Sune O.; Birks, Hilary H.; Blockley, Simon P. E.; Brauer, Achim; Hajdas, Irka; Hoek, Wim Z.; Lowe, J. John; Moreno, Ana; Renssen, Hans; Roche, Didier M.; Svensson, Anders M.; Valdes, Paul; Walker, Mike J. C.

2014-12-01

Since 2010, the INTIMATE (INTegration of Ice-core, MArine and TErrestrial records) network has been operating as a COST Action (designated ES0907). This paper outlines the accomplishments of the INTIMATE COST Action in the context of how the INTIMATE ideas have evolved during the network's twenty-year life span, and highlights a number of challenges that can guide further work. In the second part of the paper, the contributions that comprise this INTIMATE special issue are introduced.

A direction detective asymmetrical twin-core fiber curving sensor

NASA Astrophysics Data System (ADS)

An, Maowei; Geng, Tao; Yang, Wenlei; Zeng, Hongyi; Li, Jian

2015-10-01

Long period fiber gratings (LPFGs), which can couple the core mode to the forward propagating cladding modes of a fiber and have the advantage of small additional loss, no backward reflection, small size, which is widely used in optical fiber sensors and optical communication systems. LPFG has different fabricating methods, in order to write gratings on the twin-core at the same time effectively, we specially choose electric heating fused taper system to fabricate asymmetric dual-core long period fiber grating, because this kind of method can guarantee the similarity of gratings on the twin cores and obtain good geometric parameters of LPFG, such as cycle, cone waist. Then we use bending test platform to conduct bending test for each of the core of twin-core asymmetric long period fiber grating. Experiments show that: the sensitivity of asymmetrical twin-core long period fiber grating's central core under bending is -5.47nm·m, while the sensitivity of asymmetric twin-core long period fiber grating partial core changed with the relative position of screw micrometer. The sensitivity at 0°, 30°, 90° direction is -4.22nm·m, -9.84nm·m, -11.44nm·m respectively. The experiment results strongly demonstrate the properties of rim sensing of asymmetrical twin-core fiber gratings which provides the possibility of simultaneously measuring the bending magnitude and direction and solving the problem of cross sensing when multi-parameter measuring. In other words, we can detect temperature and bend at the same time by this sensor. As our knowledge, it is the first time simultaneously measuring bend and temperature using this structure of fiber sensors.

Advanced core-analyses for subsurface characterization

NASA Astrophysics Data System (ADS)

Pini, R.

2017-12-01

The heterogeneity of geological formations varies over a wide range of length scales and represents a major challenge for predicting the movement of fluids in the subsurface. Although they are inherently limited in the accessible length-scale, laboratory measurements on reservoir core samples still represent the only way to make direct observations on key transport properties. Yet, properties derived on these samples are of limited use and should be regarded as sample-specific (or `pseudos'), if the presence of sub-core scale heterogeneities is not accounted for in data processing and interpretation. The advent of imaging technology has significantly reshaped the landscape of so-called Special Core Analysis (SCAL) by providing unprecedented insight on rock structure and processes down to the scale of a single pore throat (i.e. the scale at which all reservoir processes operate). Accordingly, improved laboratory workflows are needed that make use of such wealth of information by e.g., referring to the internal structure of the sample and in-situ observations, to obtain accurate parameterisation of both rock- and flow-properties that can be used to populate numerical models. We report here on the development of such workflow for the study of solute mixing and dispersion during single- and multi-phase flows in heterogeneous porous systems through a unique combination of two complementary imaging techniques, namely X-ray Computed Tomography (CT) and Positron Emission Tomography (PET). The experimental protocol is applied to both synthetic and natural porous media, and it integrates (i) macroscopic observations (tracer effluent curves), (ii) sub-core scale parameterisation of rock heterogeneities (e.g., porosity, permeability and capillary pressure), and direct 3D observation of (iii) fluid saturation distribution and (iv) the dynamic spreading of the solute plumes. Suitable mathematical models are applied to reproduce experimental observations, including both 1D and 3D numerical schemes populated with the parameterisation above. While it validates the core-flooding experiments themselves, the calibrated mathematical model represents a key element for extending them to conditions prevalent in the subsurface, which would be otherwise not attainable in the laboratory.

Rehabilitation Counselor Preparation for Working with Youth with Psychiatric Disabilities

ERIC Educational Resources Information Center

Mellin, Elizabeth A.; Hunt, Brandon; Lorenz, Dawn C.

2009-01-01

Faculty in CORE-accredited rehabilitation counseling programs (N = 46) were surveyed to assess preparation for work with youth with psychiatric disabilities and to identify barriers to developing and maintaining a specialization focused on this population within the curriculum. Although faculty reported that students enrolled in their programs…

[VIEW Level, Special Education Core Curriculum Manual.] I.E.P. Development Guide.

ERIC Educational Resources Information Center

Bergen County Region III, Demerest, NJ. Div. of Special Education.

The Individualized Educational Program development guide is intended for handicapped students at the VIEW level (Vocational Instruction and Experience Workshop). Goals, objectives, and activities are specified for each of seven categories (sample subsections in parentheses): (1) assembly skills (collating, sorting, filing, folding); (2)…

Leisure Service Career Programs Model. Final Report.

ERIC Educational Resources Information Center

Twining, Marilyn

This report identifies leisure career occupations, determines the occupational outlook, and develops primary core competencies as well as specialized, optional competencies for entry level employment. The main method of inquiry is described as a needs assessment based on an audit at Moraine Valley Community College, two previous studies by the…

Setting Clear Learning Targets to Guide Instruction for All Students

ERIC Educational Resources Information Center

Konrad, Moira; Keesey, Susan; Ressa, Virginia A.; Alexeeff, Maggie; Chan, Paula E.; Peters, Mary T.

2014-01-01

As more states adopt the Common Core State Standards, teachers face new challenges. Teachers must unpack these standards and develop explicit learning targets to make these rigorous standards accessible to their students. This task can be especially challenging for special educators who must balance standards-based education with individualized…

Two-Year Core Curriculum for Agricultural Education in Montana. Revised.

ERIC Educational Resources Information Center

Montana State Univ., Bozeman. Dept. of Agricultural and Industrial Education.

This guide contains suggested units of instruction for the first two years of instruction in secondary vocational agriculture. It is intended to aid teachers and administrators in planning instructional programs to equip students with essential basic competencies required for more specialized programs. Instructor materials include information on…

ADP's ABCs of Training

ERIC Educational Resources Information Center

Weinstein, Margery

2010-01-01

When a company's core competence is processing data, it is sometimes easy to lose sight of the obvious--the information right under its nose. In the case of Automatic Data Processing, Inc. (ADP), a business outsourcing company specializing in human resources, payroll, tax, and benefits administrations solutions, that is not a problem. Through…

Word and World Reading: Evaluation Report and Executive Summary

ERIC Educational Resources Information Center

See, Beng Huat; Gorard, Stephen; Siddiqui, Nadia

2015-01-01

The Word and World Reading programme aimed to improve the reading comprehension and wider literacy skills of children aged 7-9 from low income families. The programme focused on improving the vocabulary and background knowledge (sometimes labelled "core knowledge") of pupils, through the use of specially designed "knowledge…

"Special Delivery": Case Studies in Alternative Teacher Licensure Programs for Students of Color.

ERIC Educational Resources Information Center

Hasslen, Robin; Green, Les

St. Cloud State University's Teacher of Color project provides alternate licensure for degreed individuals needing only to complete their teacher education core and subject area coursework. It offers minority students on- and off-campus programs, financial support, flexible hours, and a compressed program. Researchers examined participating…

INTERMAGNET and magnetic observatories

USGS Publications Warehouse

Love, Jeffrey J.; Chulliat, Arnaud

2012-01-01

A magnetic observatory is a specially designed ground-based facility that supports time-series measurement of the Earth’s magnetic field. Observatory data record a superposition of time-dependent signals related to a fantastic diversity of physical processes in the Earth’s core, mantle, lithosphere, ocean, ionosphere, magnetosphere, and, even, the Sun and solar wind.

An Intelligent Tutor-Assisted Mathematics Intervention Program for Students with Learning Difficulties

ERIC Educational Resources Information Center

Xin, Yan Ping; Tzur, Ron; Hord, Casey; Liu, Jia; Park, Joo Young; Si, Luo

2017-01-01

The Common Core Mathematics Standards have raised expectations for schools and students in the United States. These standards demand much deeper content knowledge from teachers of mathematics and their students. Given the increasingly diverse student population in today's classrooms and shortage of qualified special education teachers,…

The Implementation of Graduate Education to Professional Performance: Teachers' Perspectives

ERIC Educational Resources Information Center

Berkant, Hasan Güner; Baysal, Seda

2017-01-01

One of the core figures of education system is undoubtfully the teacher who is expected to contribute dramatically to the qualified learning environment both with professional skills and with personal characteristics. Therefore, the need for graduate education and its significance to specialize in maintaining education after Bachelor's degree has…

Private Industry and the Disadvantaged Worker.

ERIC Educational Resources Information Center

Shelly (E.F.) and Co., New York, NY.

Although publicized figures indicate that private industry has hired over 100,000 "hard-core" nationally, this study identified less than 10,000 persons who were receiving special training. Data on the successes, failures and problems of training programs were obtained by questionnaire from 224 companies with a total work force of over…

The Mandate Is Still Being Honored: In Defense of Weber's Disciples.

ERIC Educational Resources Information Center

Scott, W. Richard

1996-01-01

Stern and Barley's article in this same "Administrative Science Quarterly" issue gives too much attention to work appearing in the core organization journals and not enough to findings reported in broader and more specialized social-science journals and the book literature. Surveying this broader domain suggests that organizational…

Development and Measurement of Preschoolers' Quantitative Knowledge

ERIC Educational Resources Information Center

Geary, David C.

2015-01-01

The collection of studies in this special issue make an important contribution to our understanding and measurement of the core cognitive and noncognitive factors that influence children's emerging quantitative competencies. The studies also illustrate how the field has matured, from a time when the quantitative competencies of infants and young…

Preparing to Teach in Secondary Schools

ERIC Educational Resources Information Center

Brooks, Valerie, Ed.; Abbott, Ian, Ed.; Bills, Liz, Ed.

2004-01-01

This book is key reading for all trainee secondary school teachers. It covers the range of core professional skills that student teachers need to acquire irrespective of their subject specialism or their training route. It also considers recent developments in teaching, exploring the opportunities and challenges they present for those about to…

The NATA code; theory and analysis. Volume 3: Programmer's manual. [for calculating flow in arc-heated wind tunnels and conditions on models tested in reentry simulation

NASA Technical Reports Server (NTRS)

Bade, W. L.; Yos, J. M.

1975-01-01

The present, third volume of the final report is a programmer's manual for the code. It provides a listing of the FORTRAN 4 source program; a complete glossary of FORTRAN symbols; a discussion of the purpose and method of operation of each subroutine (including mathematical analyses of special algorithms); and a discussion of the operation of the code on IBM/360 and UNIVAC 1108 systems, including required control cards and the overlay structure used to accommodate the code to the limited core size of the 1108. In addition, similar information is provided to document the programming of the NOZFIT code, which is employed to set up nozzle profile curvefits for use in NATA.

Earliest isotopic evidence in the Maya region for animal management and long-distance trade at the site of Ceibal, Guatemala

PubMed Central

Emery, Kitty F.; Inomata, Takeshi; Triadan, Daniela; Kamenov, George D.; Krigbaum, John

2018-01-01

This study uses a multiisotope (carbon, nitrogen, oxygen, and strontium) approach to examine early animal management in the Maya region. An analysis of faunal specimens across almost 2,000 years (1000 BC to AD 950) at the site of Ceibal, Guatemala, reveals the earliest evidence for live-traded dogs and possible captive-reared taxa in the Americas. These animals may have been procured for ceremonial functions based on their location in the monumental site core, suggesting that animal management and trade began in the Maya area to promote special events, activities that were critical in the development of state society. Isotopic evidence for animal captivity at Ceibal reveals that animal management played a greater role in Maya communities than previously believed. PMID:29555750

Improved 3-D turbomachinery CFD algorithm

NASA Technical Reports Server (NTRS)

Janus, J. Mark; Whitfield, David L.

1988-01-01

The building blocks of a computer algorithm developed for the time-accurate flow analysis of rotating machines are described. The flow model is a finite volume method utilizing a high resolution approximate Riemann solver for interface flux definitions. This block LU implicit numerical scheme possesses apparent unconditional stability. Multi-block composite gridding is used to orderly partition the field into a specified arrangement. Block interfaces, including dynamic interfaces, are treated such as to mimic interior block communication. Special attention is given to the reduction of in-core memory requirements by placing the burden on secondary storage media. Broad applicability is implied, although the results presented are restricted to that of an even blade count configuration. Several other configurations are presently under investigation, the results of which will appear in subsequent publications.

Twin-Core Fiber-Based Mach Zehnder Interferometer for Simultaneous Measurement of Strain and Temperature

PubMed Central

Kowal, Dominik; Urbanczyk, Waclaw; Mergo, Pawel

2018-01-01

In this paper we present an all-fiber interferometric sensor for the simultaneous measurement of strain and temperature. It is composed of a specially fabricated twin-core fiber spliced between two pieces of a single-mode fiber. Due to the refractive index difference between the two cores in a twin-core fiber, a differential interference pattern is produced at the sensor output. The phase response of the interferometer to strain and temperature is measured in the 850–1250 nm spectral range, showing zero sensitivity to strain at 1000 nm. Due to the significant difference in sensitivities to both parameters, our interferometer is suitable for two-parameter sensing. The simultaneous response of the interferometer to strain and temperature was studied using the two-wavelength interrogation method and a novel approach based on the spectral fitting of the differential phase response. As the latter technique uses all the gathered spectral information, it is more reliable and yields the results with better accuracy. PMID:29558386

Strength and deformability of concrete beams reinforced by non-metallic fiber and composite rebar

NASA Astrophysics Data System (ADS)

Kudyakov, K. L.; Plevkov, V. S.; Nevskii, A. V.

2015-01-01

Production of durable and high-strength concrete structures with unique properties has always been crucial. Therefore special attention has been paid to non-metallic composite and fiber reinforcement. This article describes the experimental research of strength and deformability of concrete beams with dispersed and core fiber-based reinforcement. As composite reinforcement fiberglass reinforced plastic rods with diameters 6 mm and 10 mm are used. Carbon and basalt fibers are used as dispersed reinforcement. The developed experimental program includes designing and production of flexural structures with different parameters of dispersed fiber and composite rebar reinforcement. The preliminary testing of mechanical properties of these materials has shown their effectiveness. Structures underwent bending testing on a special bench by applying flexural static load up to complete destruction. During the tests vertical displacements were recorded, as well as value of actual load, slippage of rebars in concrete, crack formation. As a result of research were obtained structural failure and crack formation graphs, value of fracture load and maximum displacements of the beams at midspan. Analysis of experimental data showed the effectiveness of using dispersed reinforcement of concrete and the need for prestressing of fiberglass composite rebar.

Scribl: an HTML5 Canvas-based graphics library for visualizing genomic data over the web

PubMed Central

Miller, Chase A.; Anthony, Jon; Meyer, Michelle M.; Marth, Gabor

2013-01-01

Motivation: High-throughput biological research requires simultaneous visualization as well as analysis of genomic data, e.g. read alignments, variant calls and genomic annotations. Traditionally, such integrative analysis required desktop applications operating on locally stored data. Many current terabyte-size datasets generated by large public consortia projects, however, are already only feasibly stored at specialist genome analysis centers. As even small laboratories can afford very large datasets, local storage and analysis are becoming increasingly limiting, and it is likely that most such datasets will soon be stored remotely, e.g. in the cloud. These developments will require web-based tools that enable users to access, analyze and view vast remotely stored data with a level of sophistication and interactivity that approximates desktop applications. As rapidly dropping cost enables researchers to collect data intended to answer questions in very specialized contexts, developers must also provide software libraries that empower users to implement customized data analyses and data views for their particular application. Such specialized, yet lightweight, applications would empower scientists to better answer specific biological questions than possible with general-purpose genome browsers currently available. Results: Using recent advances in core web technologies (HTML5), we developed Scribl, a flexible genomic visualization library specifically targeting coordinate-based data such as genomic features, DNA sequence and genetic variants. Scribl simplifies the development of sophisticated web-based graphical tools that approach the dynamism and interactivity of desktop applications. Availability and implementation: Software is freely available online at http://chmille4.github.com/Scribl/ and is implemented in JavaScript with all modern browsers supported. Contact: gabor.marth@bc.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:23172864

Publications - GMC 418 | Alaska Division of Geological & Geophysical

Science.gov Websites

DGGS GMC 418 Publication Details Title: Porosity, permeability, grain density core analysis (CT scans , permeability, grain density core analysis (CT scans), and core photos from the ConocoPhillips N. Cook Inlet

Cytotoxicity, genotoxicity, transplacental transfer and tissue disposition in pregnant rats mediated by nanoparticles: the case of magnetic core mesoporous silica nanoparticles.

PubMed

Pinto, Suyene Rocha; Helal-Neto, Edward; Paumgartten, Francisco; Felzenswalb, Israel; Araujo-Lima, Carlos Fernando; Martínez-Máñez, Ramón; Santos-Oliveira, Ralph

2018-04-24

Whether in the cosmetic or as therapeutic, the use of nanoparticles has been increasing and taking on global proportion. However, there are few studies about the physical potential of long-term use or use in special conditions such as chronic, AIDS, pregnant women and other special health circumstances. In this context, the study of the mutagenicity and the transplacental passage represents an important and reliable model for the primary evaluation of potential health risks, especially maternal and child health. In this study we performed mutagenicity, cytotoxic and transplacental evaluation of magnetic core mesoporous silica nanoparticles, radiolabeled with 99m Tc for determination of toxicogenic and embryonic/fetuses potential risk in animal model. Magnetic core mesoporous silica nanoparticles were produced and characterized by obtaining nanoparticles with a size of (58.9 ± 8.1 nm) in spherical shape and with intact magnetic core. The 99 m Tc radiolabeling process demonstrated high efficacy and stability in 98% yield over a period of 8 hours of stability. Mutagenicity assays were performed using Salmonella enteric serovar Typhimurium standard strains TA98, TA100 and TA102. Cytotoxicity assays were performed using WST-1. The transplacental evaluation assays were performed using the in vivo model with rats in two periods: embryonic and fetal stage. The results of both analyzes corroborate that the nanoparticles can i) generate DNA damage; ii) generate cytotoxic potential and iii) cross the transplantation barrier in both stages and bioaccumulates in both embryos and fetuses. The results suggest that complementary evaluations should be conducted in order to attest safety, efficacy and quality of nanoparticles before unrestricted approval of their use.

Pathview Web: user friendly pathway visualization and data integration.

PubMed

Luo, Weijun; Pant, Gaurav; Bhavnasi, Yeshvant K; Blanchard, Steven G; Brouwer, Cory

2017-07-03

Pathway analysis is widely used in omics studies. Pathway-based data integration and visualization is a critical component of the analysis. To address this need, we recently developed a novel R package called Pathview. Pathview maps, integrates and renders a large variety of biological data onto molecular pathway graphs. Here we developed the Pathview Web server, as to make pathway visualization and data integration accessible to all scientists, including those without the special computing skills or resources. Pathview Web features an intuitive graphical web interface and a user centered design. The server not only expands the core functions of Pathview, but also provides many useful features not available in the offline R package. Importantly, the server presents a comprehensive workflow for both regular and integrated pathway analysis of multiple omics data. In addition, the server also provides a RESTful API for programmatic access and conveniently integration in third-party software or workflows. Pathview Web is openly and freely accessible at https://pathview.uncc.edu/. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

New Frontiers in Analyzing Dynamic Group Interactions: Bridging Social and Computer Science

PubMed Central

Lehmann-Willenbrock, Nale; Hung, Hayley; Keyton, Joann

2017-01-01

This special issue on advancing interdisciplinary collaboration between computer scientists and social scientists documents the joint results of the international Lorentz workshop, “Interdisciplinary Insights into Group and Team Dynamics,” which took place in Leiden, The Netherlands, July 2016. An equal number of scholars from social and computer science participated in the workshop and contributed to the papers included in this special issue. In this introduction, we first identify interaction dynamics as the core of group and team models and review how scholars in social and computer science have typically approached behavioral interactions in groups and teams. Next, we identify key challenges for interdisciplinary collaboration between social and computer scientists, and we provide an overview of the different articles in this special issue aimed at addressing these challenges. PMID:29249891

New Frontiers in Analyzing Dynamic Group Interactions: Bridging Social and Computer Science.

PubMed

Lehmann-Willenbrock, Nale; Hung, Hayley; Keyton, Joann

2017-10-01

This special issue on advancing interdisciplinary collaboration between computer scientists and social scientists documents the joint results of the international Lorentz workshop, "Interdisciplinary Insights into Group and Team Dynamics," which took place in Leiden, The Netherlands, July 2016. An equal number of scholars from social and computer science participated in the workshop and contributed to the papers included in this special issue. In this introduction, we first identify interaction dynamics as the core of group and team models and review how scholars in social and computer science have typically approached behavioral interactions in groups and teams. Next, we identify key challenges for interdisciplinary collaboration between social and computer scientists, and we provide an overview of the different articles in this special issue aimed at addressing these challenges.

Cost of Equity Estimation in Fuel and Energy Sector Companies Based on CAPM

NASA Astrophysics Data System (ADS)

Kozieł, Diana; Pawłowski, Stanisław; Kustra, Arkadiusz

2018-03-01

The article presents cost of equity estimation of capital groups from the fuel and energy sector, listed at the Warsaw Stock Exchange, based on the Capital Asset Pricing Model (CAPM). The objective of the article was to perform a valuation of equity with the application of CAPM, based on actual financial data and stock exchange data and to carry out a sensitivity analysis of such cost, depending on the financing structure of the entity. The objective of the article formulated in this manner has determined its' structure. It focuses on presentation of substantive analyses related to the core of equity and methods of estimating its' costs, with special attention given to the CAPM. In the practical section, estimation of cost was performed according to the CAPM methodology, based on the example of leading fuel and energy companies, such as Tauron GE and PGE. Simultaneously, sensitivity analysis of such cost was performed depending on the structure of financing the company's operation.

A panel method study of vortex sheets with special emphasis on sheets of axisymmetric geometry. M.S. Thesis

NASA Technical Reports Server (NTRS)

Sugioka, I.; Widnall, S. E.

1985-01-01

The self induced evolution of a vortex sheet was simulated by modeling the sheet using an integration of discrete elements of vorticity. Replacing small sections of a vortex sheet by flat panels of constant vorticity is found to reproduce more accurately the initial conditions for the Lagrangian simulation technique than replacement by point vortices. The flat panel method for the vortex sheet was then extended to model axisymmetric vortex sheets. The local and far field velocities induced by the axisymmetric panels were obtained using matched asymptotic analysis, and some of the uncertainties involved in other models of the axisymmetric vortex sheet have been eliminated. One important result of this analysis is the determination of the proper choice of core size for a circular vortex filament which may replace a section of an axisymmetric vortex sheet. Roll-up of both two dimensional and axisymmetric vortex sheets was computed using the panel methods developed in the report.

Real time emotion aware applications: a case study employing emotion evocative pictures and neuro-physiological sensing enhanced by Graphic Processor Units.

PubMed

Konstantinidis, Evdokimos I; Frantzidis, Christos A; Pappas, Costas; Bamidis, Panagiotis D

2012-07-01

In this paper the feasibility of adopting Graphic Processor Units towards real-time emotion aware computing is investigated for boosting the time consuming computations employed in such applications. The proposed methodology was employed in analysis of encephalographic and electrodermal data gathered when participants passively viewed emotional evocative stimuli. The GPU effectiveness when processing electroencephalographic and electrodermal recordings is demonstrated by comparing the execution time of chaos/complexity analysis through nonlinear dynamics (multi-channel correlation dimension/D2) and signal processing algorithms (computation of skin conductance level/SCL) into various popular programming environments. Apart from the beneficial role of parallel programming, the adoption of special design techniques regarding memory management may further enhance the time minimization which approximates a factor of 30 in comparison with ANSI C language (single-core sequential execution). Therefore, the use of GPU parallel capabilities offers a reliable and robust solution for real-time sensing the user's affective state. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

The influence of geometric imperfections on the stability of three-layer beams with foam core

NASA Astrophysics Data System (ADS)

Wstawska, Iwona

2017-01-01

The main objective of this work is the numerical analysis (FE analysis) of stability of three-layer beams with metal foam core (alumina foam core). The beams were subjected to pure bending. The analysis of the local buckling was performed. Furthermore, the influence of geometric parameters of the beam and material properties of the core (linear and non-linear model) on critical loads values and buckling shape were also investigated. The calculations were made on a family of beams with different mechanical properties of the core (elastic and elastic-plastic material). In addition, the influence of geometric imperfections on deflection and normal stress values of the core and the faces has been evaluated.

A Finite Element Analysis for Predicting the Residual Compressive Strength of Impact-Damaged Sandwich Panels

NASA Technical Reports Server (NTRS)

Ratcliffe, James G.; Jackson, Wade C.

2008-01-01

A simple analysis method has been developed for predicting the residual compressive strength of impact-damaged sandwich panels. The method is tailored for honeycomb core-based sandwich specimens that exhibit an indentation growth failure mode under axial compressive loading, which is driven largely by the crushing behavior of the core material. The analysis method is in the form of a finite element model, where the impact-damaged facesheet is represented using shell elements and the core material is represented using spring elements, aligned in the thickness direction of the core. The nonlinear crush response of the core material used in the analysis is based on data from flatwise compression tests. A comparison with a previous analysis method and some experimental data shows good agreement with results from this new approach.

A Finite Element Analysis for Predicting the Residual Compression Strength of Impact-Damaged Sandwich Panels

NASA Technical Reports Server (NTRS)

Ratcliffe, James G.; Jackson, Wade C.

2008-01-01

A simple analysis method has been developed for predicting the residual compression strength of impact-damaged sandwich panels. The method is tailored for honeycomb core-based sandwich specimens that exhibit an indentation growth failure mode under axial compression loading, which is driven largely by the crushing behavior of the core material. The analysis method is in the form of a finite element model, where the impact-damaged facesheet is represented using shell elements and the core material is represented using spring elements, aligned in the thickness direction of the core. The nonlinear crush response of the core material used in the analysis is based on data from flatwise compression tests. A comparison with a previous analysis method and some experimental data shows good agreement with results from this new approach.

Trace: a high-throughput tomographic reconstruction engine for large-scale datasets.

PubMed

Bicer, Tekin; Gürsoy, Doğa; Andrade, Vincent De; Kettimuthu, Rajkumar; Scullin, William; Carlo, Francesco De; Foster, Ian T

2017-01-01

Modern synchrotron light sources and detectors produce data at such scale and complexity that large-scale computation is required to unleash their full power. One of the widely used imaging techniques that generates data at tens of gigabytes per second is computed tomography (CT). Although CT experiments result in rapid data generation, the analysis and reconstruction of the collected data may require hours or even days of computation time with a medium-sized workstation, which hinders the scientific progress that relies on the results of analysis. We present Trace, a data-intensive computing engine that we have developed to enable high-performance implementation of iterative tomographic reconstruction algorithms for parallel computers. Trace provides fine-grained reconstruction of tomography datasets using both (thread-level) shared memory and (process-level) distributed memory parallelization. Trace utilizes a special data structure called replicated reconstruction object to maximize application performance. We also present the optimizations that we apply to the replicated reconstruction objects and evaluate them using tomography datasets collected at the Advanced Photon Source. Our experimental evaluations show that our optimizations and parallelization techniques can provide 158× speedup using 32 compute nodes (384 cores) over a single-core configuration and decrease the end-to-end processing time of a large sinogram (with 4501 × 1 × 22,400 dimensions) from 12.5 h to <5 min per iteration. The proposed tomographic reconstruction engine can efficiently process large-scale tomographic data using many compute nodes and minimize reconstruction times.

Library Functions, Scholarly Communication, and the Foundation of the Digital Library: Laying Claim to the Control Zone.

ERIC Educational Resources Information Center

Atkinson, Ross

1996-01-01

Discussion of academic libraries and online systems focuses on core library services and a digital library which could serve as an alternative publishing mechanism for specialized scholarly communication. Highlights include adding value to sources of information; conflicts, including those with commercial publishers; and standardization and…

Teaching Self-Determination: Empowered Teachers, Empowered Students

ERIC Educational Resources Information Center

Jones, Melissa

2006-01-01

A popular term in contemporary special education circles is "empowerment," but what does it actually mean to be an empowered individual? Although many definitions exist in the literature and include such terms such as self-determination and self-advocacy, at the core of empowerment is the understanding that an individual is truly empowered the…

A Module-Based Approach: Training Paraeducators on Evidence-Based Practices

ERIC Educational Resources Information Center

Da Fonte, M. Alexandra; Capizzi, Andrea M.

2015-01-01

Paraeducators are on the front lines in special education settings, providing support to teachers and students with significant disabilities and specific health-care needs. The important role they play demands efficient and cost-effective training in core skills. This study utilized a multiple-baseline across behaviors design to evaluate a…

Low cost, formable, high T(sub c) superconducting wire

NASA Technical Reports Server (NTRS)

Smialek, James L. (Inventor)

1991-01-01

A ceramic superconductivity part such as a wire is produced through the partial oxidation of a specially formulated copper alloy in the core. The alloys contain low level quantities of rare earth and alkaline earth dopant elements. Upon oxidation at high temperature, superconducting oxide phases are formed as a thin film.

Vocabulary Acquisition in an Academic Discipline: ESL Learners and Theology.

ERIC Educational Resources Information Center

Lessard-Clouston, Michael

A study investigated and compared the acquisition of specialized vocabulary among English-as-a-Second Language (ESL) and native English-speaking (NES) graduate students in theology. Research was undertaken in an anglophone city in central Canada. Subjects were 12 students (5 Chinese ESLs, 7 NESs) enrolled in an introductory core theology course. A…

The Post-Human I: Encountering "Data" in New Materialism

ERIC Educational Resources Information Center

Somerville, Margaret

2016-01-01

The editors of a recent special edition of "Qualitative Studies in Education" map a new field of post-qualitative research and raise fundamental questions about core concepts such as "method" and "data." They ask whether qualitative inquiry as we know it is any longer possible if we understand language, the human and…

Educating Children with Multiple Disabilities: A Collaborative Approach. Fourth Edition

ERIC Educational Resources Information Center

Orelove, Fred P., Ed.; Sobsey, Dick, Ed.; Silberman, Rosanne K., Ed.

2004-01-01

Now in its fourth edition, this highly respected, bestselling textbook gives undergraduate and graduate students up-to-the-minute research and strategies for educating children with severe and multiple disabilities. This popular core text--for 15 years, a staple of teacher training programs in special education and related fields--thoroughly…

75 FR 70057 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-16

..., and deals with U.S. securities laws, regulations, sales practices and special products drawn from the standard Series 7 examination. The Series 37 version is for Canadian registrants who have successfully completed the basic core module of the CSI Global Education (``CSI'', formerly the Canadian Securities...

75 FR 70052 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-16

..., and deals with U.S. securities laws, regulations, sales practices and special products drawn from the standard Series 7 examination. The Series 37 version is for Canadian registrants who have successfully completed the basic core module of the CSI Global Education (``CSI'', formerly the Canadian Securities...

Emerging Evidence for Instructional Practice: Repeated Viewings of Sign Language Models

ERIC Educational Resources Information Center

Beal-Alvarez, Jennifer S.; Huston, Sandra G.

2014-01-01

Current initiatives in education, such as No Child Left Behind and the National Common Core Standards movement, call for the use of evidence-based practices, or those instructional practices that are supported by documentation of their effectiveness related to student learning outcomes, including students with special needs. While hearing loss is…

Cognitive Aging and Computer-Based Instructional Design: Where Do We Go from Here?

ERIC Educational Resources Information Center

Van Gerven, Pascal W. M.; Paas, Fred; Tabbers, Huib K.

2006-01-01

In this article, the most relevant literature on cognitive aging and instructional design is merged to formulate recommendations for designing computer-based training material aimed at elderly learners. The core message is that researchers and instructional designers do not need to develop special computerized instruction for older adults. Rather,…

Inclusive Instruction: Evidence-Based Practices for Teaching Students with Disabilities. What Works for Special-Needs Learners Series

ERIC Educational Resources Information Center

Brownell, Mary T.; Smith, Sean J.; Crockett, Jean B.; Griffin, Cynthia C.

2012-01-01

This accessible book presents research-based strategies for supporting K-8 students with high-incidence disabilities to become accomplished learners. The authors clearly describe the core components of effective inclusive instruction, showing how to recognize and respond to individual students' needs quickly and appropriately. Teachers are…

Preschool Education in Today's World: Teaching Children with Diverse Backgrounds and Abilities

ERIC Educational Resources Information Center

Burns, M. Susan; Johnson, Richard T.; Assaf, Mona M.

2012-01-01

Future early childhood educators need to know how to teach "all" young learners effectively--including children with diverse cultural, linguistic, and economic backgrounds and children with special needs. This core textbook equips early childhood educators with the knowledge they'll need to succeed in the classroom and ensure the best…

Technology Transfer and Innovation Initiatives in Strategic Management: Generating an Alternative Perspective

ERIC Educational Resources Information Center

Major, E.

2003-01-01

This paper taps the strategic management discipline to inform our understanding of technology transfer and innovation (TTI) initiatives. With special focus on the UK Foresight programme it considers the impacts that the resource-based and core competence approaches to strategy can have on understanding the nature and effectiveness of TTI…

Listening to What Cannot Be Said: Broken Narratives and the Lived Body

ERIC Educational Resources Information Center

Kokanovic, Renata; Stone, Meredith

2018-01-01

The core of this special issue of "Arts and Humanities in Higher Education" emerged from the "Broken Narratives and the Lived Body" conference held in 2016. The "Broken Narrative" essays included in this issue open up a critical space for understanding and theorising illness narratives that defy a conventional…

Comparative genomics and prediction of conditionally dispensable sequences in legume-infecting Fusarium oxysporum formae speciales facilitates identification of candidate effectors

USDA-ARS?s Scientific Manuscript database

Focusing on the identification of pathogenicity gene content, we leveraged the reference genomes of Fusarium pathogens F. oxysporum f. sp. lycopersici (tomato-infecting) and F. solani (pea-infecting) and their well-characterised core and dispensable chromosomes to predict genomic organisation in the...

Parallel Distributed Processing at 25: Further Explorations in the Microstructure of Cognition

ERIC Educational Resources Information Center

Rogers, Timothy T.; McClelland, James L.

2014-01-01

This paper introduces a special issue of "Cognitive Science" initiated on the 25th anniversary of the publication of "Parallel Distributed Processing" (PDP), a two-volume work that introduced the use of neural network models as vehicles for understanding cognition. The collection surveys the core commitments of the PDP…

Bridges to Student Success: NASPA and NCDS Present 2003 Exemplary Programs.

ERIC Educational Resources Information Center

National Association of Student Personnel Administrators, Inc.

This special community college edition of "Bridges to Student Success" serves to showcase the important role of student services within the community college and to highlight the creative initiatives at the core of the community college mission. This publication invited five community college leaders, many of whom began their careers in student…

Trends in Image Use by Historians and the Implications for Librarians and Archivists

ERIC Educational Resources Information Center

Harris, Valerie; Hepburn, Peter

2013-01-01

For years, libraries have offered reproduction services to users, with historians being the core audience. More recently, archives and special collections have developed digitization programs to make primary sources widely available through the Internet. The authors tracked image use from 2000 through 2009 in journals from the discipline of…

77 FR 28397 - National Institute of Arthritis and Musculoskeletal and Skin Diseases; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-14

... Arthritis and Musculoskeletal and Skin Diseases Special Emphasis Panel, P30 Rheumatic Diseases Core Center... Arthritis and Musculoskeletal and Skin Diseases; Notice of Closed Meeting Pursuant to section 10(d) of the..., Musculoskeletal and Skin Diseases, National Institutes of Health, 6701 Democracy Blvd., Suite 800, Bethesda, MD...

High temperature thermocouple development program, part A and part B

NASA Technical Reports Server (NTRS)

Toenshoff, D. A.; Zysk, E. D.; Fleischner, P. L.

1972-01-01

The problem of extending the useful life of thermocouples intended for in-core and out-of-core thermionic applications in a vacuum environment at temperatures up to 2273 K for periods of time up to 10,000 hours was investigated. Many factors that may influence this useful life were examined, and a basic probe design was developed. With a few modifications, twenty-three thermocouple assemblies were fabricated. Generally the finished thermocouple consisted of solid doped W-3% Re and W-25% Re wires and high purity and high density BeO insulators, and was sheathed in a high purity tantalum tube. In a few probes, stranded thermocouple wires were substituted; commercial grade BeO was used; and in two cases, CVD W-22% Re tubing was used. Each of the components was made of the highest purity materials available; was subjected to special cleaning steps, and was assembled in a class 10,000 clean room. Pertinent physical and chemical properties were determined on each of the components. Special processing techniques were used in the fabrication of the high purity (99.95%), high density (over 95% of theoretical) BeO.

Comparative genomics and prediction of conditionally dispensable sequences in legume-infecting Fusarium oxysporum formae speciales facilitates identification of candidate effectors.

PubMed

Williams, Angela H; Sharma, Mamta; Thatcher, Louise F; Azam, Sarwar; Hane, James K; Sperschneider, Jana; Kidd, Brendan N; Anderson, Jonathan P; Ghosh, Raju; Garg, Gagan; Lichtenzveig, Judith; Kistler, H Corby; Shea, Terrance; Young, Sarah; Buck, Sally-Anne G; Kamphuis, Lars G; Saxena, Rachit; Pande, Suresh; Ma, Li-Jun; Varshney, Rajeev K; Singh, Karam B

2016-03-05

Soil-borne fungi of the Fusarium oxysporum species complex cause devastating wilt disease on many crops including legumes that supply human dietary protein needs across many parts of the globe. We present and compare draft genome assemblies for three legume-infecting formae speciales (ff. spp.): F. oxysporum f. sp. ciceris (Foc-38-1) and f. sp. pisi (Fop-37622), significant pathogens of chickpea and pea respectively, the world's second and third most important grain legumes, and lastly f. sp. medicaginis (Fom-5190a) for which we developed a model legume pathosystem utilising Medicago truncatula. Focusing on the identification of pathogenicity gene content, we leveraged the reference genomes of Fusarium pathogens F. oxysporum f. sp. lycopersici (tomato-infecting) and F. solani (pea-infecting) and their well-characterised core and dispensable chromosomes to predict genomic organisation in the newly sequenced legume-infecting isolates. Dispensable chromosomes are not essential for growth and in Fusarium species are known to be enriched in host-specificity and pathogenicity-associated genes. Comparative genomics of the publicly available Fusarium species revealed differential patterns of sequence conservation across F. oxysporum formae speciales, with legume-pathogenic formae speciales not exhibiting greater sequence conservation between them relative to non-legume-infecting formae speciales, possibly indicating the lack of a common ancestral source for legume pathogenicity. Combining predicted dispensable gene content with in planta expression in the model legume-infecting isolate, we identified small conserved regions and candidate effectors, four of which shared greatest similarity to proteins from another legume-infecting ff. spp. We demonstrate that distinction of core and potential dispensable genomic regions of novel F. oxysporum genomes is an effective tool to facilitate effector discovery and the identification of gene content possibly linked to host specificity. While the legume-infecting isolates didn't share large genomic regions of pathogenicity-related content, smaller regions and candidate effector proteins were highly conserved, suggesting that they may play specific roles in inducing disease on legume hosts.

Evaluation of Analysis Techniques for Fluted-Core Sandwich Cylinders

NASA Technical Reports Server (NTRS)

Lovejoy, Andrew E.; Schultz, Marc R.

2012-01-01

Buckling-critical launch-vehicle structures require structural concepts that have high bending stiffness and low mass. Fluted-core, also known as truss-core, sandwich construction is one such concept. In an effort to identify an analysis method appropriate for the preliminary design of fluted-core cylinders, the current paper presents and compares results from several analysis techniques applied to a specific composite fluted-core test article. The analysis techniques are evaluated in terms of their ease of use and for their appropriateness at certain stages throughout a design analysis cycle (DAC). Current analysis techniques that provide accurate determination of the global buckling load are not readily applicable early in the DAC, such as during preliminary design, because they are too costly to run. An analytical approach that neglects transverse-shear deformation is easily applied during preliminary design, but the lack of transverse-shear deformation results in global buckling load predictions that are significantly higher than those from more detailed analysis methods. The current state of the art is either too complex to be applied for preliminary design, or is incapable of the accuracy required to determine global buckling loads for fluted-core cylinders. Therefore, it is necessary to develop an analytical method for calculating global buckling loads of fluted-core cylinders that includes transverse-shear deformations, and that can be easily incorporated in preliminary design.

s-core network decomposition: A generalization of k-core analysis to weighted networks

NASA Astrophysics Data System (ADS)

Eidsaa, Marius; Almaas, Eivind

2013-12-01

A broad range of systems spanning biology, technology, and social phenomena may be represented and analyzed as complex networks. Recent studies of such networks using k-core decomposition have uncovered groups of nodes that play important roles. Here, we present s-core analysis, a generalization of k-core (or k-shell) analysis to complex networks where the links have different strengths or weights. We demonstrate the s-core decomposition approach on two random networks (ER and configuration model with scale-free degree distribution) where the link weights are (i) random, (ii) correlated, and (iii) anticorrelated with the node degrees. Finally, we apply the s-core decomposition approach to the protein-interaction network of the yeast Saccharomyces cerevisiae in the context of two gene-expression experiments: oxidative stress in response to cumene hydroperoxide (CHP), and fermentation stress response (FSR). We find that the innermost s-cores are (i) different from innermost k-cores, (ii) different for the two stress conditions CHP and FSR, and (iii) enriched with proteins whose biological functions give insight into how yeast manages these specific stresses.

Wide-range structurally optimized channel for monitoring the certified power of small-core reactors

NASA Astrophysics Data System (ADS)

Koshelev, A. S.; Kovshov, K. N.; Ovchinnikov, M. A.; Pikulina, G. N.; Sokolov, A. B.

2016-12-01

The results of tests of a prototype version of a channel for monitoring the certified power of small-core reactors performed at the BR-K1 reactor at the All-Russian Scientific Research Institute of Experimental Physics are reported. An SNM-11 counter and commercial KNK-4 and KNK-3 compensated ion chambers were used as neutron detectors in the tested channel, and certified NCMM and CCMM measurement modules controlled by a PC with specialized software were used as measuring instruments. The specifics of metrological assurance of calibration of the channel in the framework of reactor power monitoring are discussed.

Wide-range structurally optimized channel for monitoring the certified power of small-core reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koshelev, A. S., E-mail: alexsander.coshelev@yandex.ru; Kovshov, K. N.; Ovchinnikov, M. A.

The results of tests of a prototype version of a channel for monitoring the certified power of small-core reactors performed at the BR-K1 reactor at the All-Russian Scientific Research Institute of Experimental Physics are reported. An SNM-11 counter and commercial KNK-4 and KNK-3 compensated ion chambers were used as neutron detectors in the tested channel, and certified NCMM and CCMM measurement modules controlled by a PC with specialized software were used as measuring instruments. The specifics of metrological assurance of calibration of the channel in the framework of reactor power monitoring are discussed.

Lithotripsy Performance of Specially Designed Laser Fiber Tips.

PubMed

Kronenberg, Peter; Traxer, Olivier

2016-05-01

We evaluated and compared a standard laser lithotripsy fiber to laser fibers claimed to have lithotripsy performance enhancing features. A special AccuMax™ 200 polished tip fiber and an AccuTrac™ ball-shaped tip fiber, each with an approximately 240 μm core, were compared to a standard 272 μm core fiber (Rocamed™). The polished and ball-shaped tip fibers were used and reused without preparation. The standard fiber was stripped and cleaved according to manufacturer instructions after each experiment. An automated laser fragmentation testing system was used to perform multiple 30-second laser lithotripsy experiments. To mimic most typical lithotripsy conditions soft and hard stone materials were used with high frequency, low pulse energy (20 Hz and 0.5 J) or with low frequency, high pulse energy (5 Hz and 2.0 J) lithotripter settings. Ablation volumes and laser fiber tip photographs before and after lithotripsy were compared. The standard and ball-shaped tip fibers did not differ in ablation volume (p = 0.72) but they ablated 174% and 188% more stone, respectively, than the polished tip fiber (p <0.0001). The ball-shaped tip showed remarkable fiber tip degradation after short-term use at low frequency, high pulse energy settings. When high pulse energy settings were applied first even for short-term use, the ablation volume achieved by the polished and ball-shaped tip fibers at high frequency, low pulse energy settings decreased more than 20%. The standard laser fiber was as good as and sometimes better than the specially designed fibers. Rapid degradation of the specially designed laser fiber tips strongly limits their general usefulness but ball-shaped tip fibers may be useful in specific situations. Copyright © 2016 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Protomagnetar and black hole formation in high-mass stars

NASA Astrophysics Data System (ADS)

Obergaulinger, M.; Aloy, M. Á.

2017-07-01

Using axisymmetric simulations coupling special relativistic magnetohydrodynamics (MHD), an approximate post-Newtonian gravitational potential and two-moment neutrino transport, we show different paths for the formation of either protomagnetars or stellar mass black holes. The fraction of prototypical stellar cores which should result in collapsars depends on a combination of several factors, among which the structure of the progenitor star and the profile of specific angular momentum are probably the foremost. Along with the implosion of the stellar core, we also obtain supernova-like explosions driven by neutrino heating and hydrodynamic instabilities or by magneto-rotational effects in cores of high-mass stars. In the latter case, highly collimated, mildly relativistic outflows are generated. We find that after a rather long post-collapse phase (lasting ≳1 s) black holes may form in cases both of successful and failed supernova-like explosions. A basic trend is that cores with a specific angular momentum smaller than that obtained by standard, one-dimensional stellar evolution calculations form black holes (and eventually collapsars). Complementary, protomagnetars result from stellar cores with the standard distribution of specific angular momentum obtained from prototypical stellar evolution calculations including magnetic torques and moderate to large mass-loss rates.

High-power picosecond pulse delivery through hollow core photonic band gap fibers

NASA Astrophysics Data System (ADS)

Michieletto, Mattia; Johansen, Mette M.; Lyngsø, Jens K.; Lægsgaard, Jesper; Bang, Ole; Alkeskjold, Thomas T.

2016-03-01

We demonstrated robust and bend insensitive fiber delivery of high power laser with diffraction limited beam quality for two different kinds of hollow core band gap fibers. The light source for this experiment consists of ytterbium-doped double clad fiber aeroGAIN-ROD-PM85 in a high power amplifier setup. It provided 22ps pulses with a maximum average power of 95W, 40MHz repetition rate at 1032nm (~2.4μJ pulse energy), with M2 <1.3. We determined the facet damage threshold for a 7-cells hollow core photonic bandgap fiber and showed up to 59W average power output for a 5 meters fiber. The damage threshold for a 19-cell hollow core photonic bandgap fiber exceeded the maximum power provided by the light source and up to 76W average output power was demonstrated for a 1m fiber. In both cases, no special attention was needed to mitigate bend sensitivity. The fibers were coiled on 8 centimeters radius spools and even lower bending radii were present. In addition, stimulated rotational Raman scattering arising from nitrogen molecules was measured through a 42m long 19 cell hollow core fiber.

Single Event Effects (SEE) Testing of Embedded DSP Cores within Microsemi RTAX4000D Field Programmable Gate Array (FPGA) Devices

NASA Technical Reports Server (NTRS)

Perez, Christopher E.; Berg, Melanie D.; Friendlich, Mark R.

2011-01-01

Motivation for this work is: (1) Accurately characterize digital signal processor (DSP) core single-event effect (SEE) behavior (2) Test DSP cores across a large frequency range and across various input conditions (3) Isolate SEE analysis to DSP cores alone (4) Interpret SEE analysis in terms of single-event upsets (SEUs) and single-event transients (SETs) (5) Provide flight missions with accurate estimate of DSP core error rates and error signatures.

An improved method for field extraction and laboratory analysis of large, intact soil cores

USGS Publications Warehouse

Tindall, J.A.; Hemmen, K.; Dowd, J.F.

1992-01-01

Various methods have been proposed for the extraction of large, undisturbed soil cores and for subsequent analysis of fluid movement within the cores. The major problems associated with these methods are expense, cumbersome field extraction, and inadequate simulation of unsaturated flow conditions. A field and laboratory procedure is presented that is economical, convenient, and simulates unsaturated and saturated flow without interface flow problems and can be used on a variety of soil types. In the field, a stainless steel core barrel is hydraulically pressed into the soil (30-cm diam. and 38 cm high), the barrel and core are extracted from the soil, and after the barrel is removed from the core, the core is then wrapped securely with flexible sheet metal and a stainless mesh screen is attached to the bottom of the core for support. In the laboratory the soil core is set atop a porous ceramic plate over which a soil-diatomaceous earth slurry has been poured to assure good contact between plate and core. A cardboard cylinder (mold) is fastened around the core and the empty space filled with paraffin wax. Soil cores were tested under saturated and unsaturated conditions using a hanging water column for potentials ???0. Breakthrough curves indicated that no interface flow occurred along the edge of the core. This procedure proved to be reliable for field extraction of large, intact soil cores and for laboratory analysis of solute transport.

Preventing War: Special Operations Engagement in Support of Security Sector Reform

DTIC Science & Technology

2014-12-04

This study analyzes recent special operations engagement in Mali and the Philippines . Through that analysis, enduring engagement, special......recent special operations engagement in Mali and the Philippines . Through that analysis, enduring engagement, special operation engagement campaigns

ICP-MS analysis of fission product diffusion in graphite for High-Temperature Gas-Cooled Reactors

NASA Astrophysics Data System (ADS)

Carter, Lukas M.

Release of radioactive fission products from nuclear fuel during normal reactor operation or in accident scenarios is a fundamental safety concern. Of paramount importance are the understanding and elucidation of mechanisms of chemical interaction, nuclear interaction, and transport phenomena involving fission products. Worldwide efforts to reduce fossil fuel dependence coupled with an increasing overall energy demand have generated renewed enthusiasm toward nuclear power technologies, and as such, these mechanisms continue to be the subjects of vigorous research. High-Temperature Gas-Cooled Reactors (HTGRs or VHTRs) remain one of the most promising candidates for the next generation of nuclear power reactors. An extant knowledge gap specific to HTGR technology derives from an incomplete understanding of fission product transport in major core materials under HTGR operational conditions. Our specific interest in the current work is diffusion in reactor graphite. Development of methods for analysis of diffusion of multiple fission products is key to providing accurate models for fission product release from HTGR core components and the reactor as a whole. In the present work, a specialized diffusion cell has been developed and constructed to facilitate real-time diffusion measurements via ICP-MS. The cell utilizes a helium gas-jet system which transports diffusing fission products to the mass spectrometer using carbon nanoparticles. The setup was designed to replicate conditions present in a functioning HTGR, and can be configured for real-time release or permeation measurements of single or multiple fission products from graphite or other core materials. In the present work, we have analyzed release rates of cesium in graphite grades IG-110, NBG-18, and a commercial grade of graphite, as well as release of iodine in IG-110. Additionally we have investigated infusion of graphite samples with Cs, I, Sr, Ag, and other surrogate fission products for use in release or profile measurements of diffusion coefficients.

Population Genetic Structure of Glycyrrhiza inflata B. (Fabaceae) Is Shaped by Habitat Fragmentation, Water Resources and Biological Characteristics.

PubMed

Yang, Lulu; Chen, Jianjun; Hu, Weiming; Yang, Tianshun; Zhang, Yanjun; Yukiyoshi, Tamura; Zhou, Yanyang; Wang, Ying

2016-01-01

Habitat fragmentation, water resources and biological characteristics are important factors that shape the genetic structure and geographical distribution of desert plants. Analysis of the relationships between these factors and population genetic variation should help to determine the evolutionary potential and conservation strategies for genetic resources for desert plant populations. As a traditional Chinese herb, Glycyrrhiza inflata B. (Fabaceae) is restricted to the fragmented desert habitat in China and has undergone a dramatic decline due to long-term over-excavation. Determining the genetic structure of the G. inflata population and identifying a core collection could help with the development of strategies to conserve this species. We investigated the genetic variation of 25 G. inflata populations based on microsatellite markers. A high level of population genetic divergence (FST = 0.257), population bottlenecks, reduced gene flow and moderate genetic variation (HE = 0.383) were detected. The genetic distances between the populations significantly correlated with the geographical distances, and this suggests that habitat fragmentation has driven a special genetic structure of G. inflata in China through isolation by distance. STRUCTURE analysis showed that G. inflata populations were structured into three clusters and that the populations belonged to multiple water systems, which suggests that water resources were related to the genetic structure of G. inflata. In addition, the biological characteristics of the perennial species G. inflata, such as its long-lived seeds, asexual reproduction, and oasis ecology, may be related to its resistance to habitat fragmentation. A core collection of G. inflata, that included 57 accessions was further identified, which captured the main allelic diversity of G. inflata. Recent habitat fragmentation has accelerated genetic divergence. The population genetic structure of G. inflata has been shaped by habitat fragmentation, water resources and biological characteristics. This genetic information and core collection will facilitate the conservation of wild germplasm and breeding of this Chinese medicinal plant.

Population Genetic Structure of Glycyrrhiza inflata B. (Fabaceae) Is Shaped by Habitat Fragmentation, Water Resources and Biological Characteristics

PubMed Central

Yang, Lulu; Chen, Jianjun; Hu, Weiming; Yang, Tianshun; Zhang, Yanjun; Yukiyoshi, Tamura; Zhou, Yanyang; Wang, Ying

2016-01-01

Background Habitat fragmentation, water resources and biological characteristics are important factors that shape the genetic structure and geographical distribution of desert plants. Analysis of the relationships between these factors and population genetic variation should help to determine the evolutionary potential and conservation strategies for genetic resources for desert plant populations. As a traditional Chinese herb, Glycyrrhiza inflata B. (Fabaceae) is restricted to the fragmented desert habitat in China and has undergone a dramatic decline due to long-term over-excavation. Determining the genetic structure of the G. inflata population and identifying a core collection could help with the development of strategies to conserve this species. Results We investigated the genetic variation of 25 G. inflata populations based on microsatellite markers. A high level of population genetic divergence (FST = 0.257), population bottlenecks, reduced gene flow and moderate genetic variation (HE = 0.383) were detected. The genetic distances between the populations significantly correlated with the geographical distances, and this suggests that habitat fragmentation has driven a special genetic structure of G. inflata in China through isolation by distance. STRUCTURE analysis showed that G. inflata populations were structured into three clusters and that the populations belonged to multiple water systems, which suggests that water resources were related to the genetic structure of G. inflata. In addition, the biological characteristics of the perennial species G. inflata, such as its long-lived seeds, asexual reproduction, and oasis ecology, may be related to its resistance to habitat fragmentation. A core collection of G. inflata, that included 57 accessions was further identified, which captured the main allelic diversity of G. inflata. Conclusions Recent habitat fragmentation has accelerated genetic divergence. The population genetic structure of G. inflata has been shaped by habitat fragmentation, water resources and biological characteristics. This genetic information and core collection will facilitate the conservation of wild germplasm and breeding of this Chinese medicinal plant. PMID:27711241

Canada's Neglected Tropical Disease Research Network: Who's in the Core—Who's on the Periphery?

PubMed Central

Phillips, Kaye; Kohler, Jillian Clare; Pennefather, Peter; Thorsteinsdottir, Halla; Wong, Joseph

2013-01-01

Background This study designed and applied accessible yet systematic methods to generate baseline information about the patterns and structure of Canada's neglected tropical disease (NTD) research network; a network that, until recently, was formed and functioned on the periphery of strategic Canadian research funding. Methodology Multiple methods were used to conduct this study, including: (1) a systematic bibliometric procedure to capture archival NTD publications and co-authorship data; (2) a country-level “core-periphery” network analysis to measure and map the structure of Canada's NTD co-authorship network including its size, density, cliques, and centralization; and (3) a statistical analysis to test the correlation between the position of countries in Canada's NTD network (“k-core measure”) and the quantity and quality of research produced. Principal Findings Over the past sixty years (1950–2010), Canadian researchers have contributed to 1,079 NTD publications, specializing in Leishmania, African sleeping sickness, and leprosy. Of this work, 70% of all first authors and co-authors (n = 4,145) have been Canadian. Since the 1990s, however, a network of international co-authorship activity has been emerging, with representation of researchers from 62 different countries; largely researchers from OECD countries (e.g. United States and United Kingdom) and some non-OECD countries (e.g. Brazil and Iran). Canada has a core-periphery NTD international research structure, with a densely connected group of OECD countries and some African nations, such as Uganda and Kenya. Sitting predominantly on the periphery of this research network is a cluster of 16 non-OECD nations that fall within the lowest GDP percentile of the network. Conclusion/Significance The publication specialties, composition, and position of NTD researchers within Canada's NTD country network provide evidence that while Canadian researchers currently remain the overall gatekeepers of the NTD research they generate; there is opportunity to leverage existing research collaborations and help advance regions and NTD areas that are currently under-developed. PMID:24340113

Recovery and Lithologic Analysis of Sediment from Hole UT-GOM2-1-H002, Green Canyon 955, Northern Gulf of Mexico

NASA Astrophysics Data System (ADS)

Kinash, N.; Cook, A.; Sawyer, D.; Heber, R.

2017-12-01

In May 2017 the University of Texas led a drilling and pressure coring expedition in the northern Gulf of Mexico, UT-GOM2-01. The holes were located in Green Canyon Block 955, where the Gulf of Mexico Joint Industry Project Leg II identified an approximately 100m thick hydrate-filled course-grained levee unit in 2009. Two separate wells were drilled into this unit: Holes H002 and H005. In Hole H002, a cutting shoe drill bit was used to collect the pressure cores, and only 1 of the 8 cores collected was pressurized during recovery. The core recovery in Hole H002 was generally poor, about 34%, while the only pressurized core had 45% recovery. In Hole H005, a face bit was used during pressure coring where 13 cores were collected and 9 cores remained pressurized. Core recovery in Hole H005 was much higher, at about 75%. The type of bit was not the only difference between the holes, however. Drilling mud was used throughout the drilling and pressure coring of Hole H002, while only seawater was used during the first 80m of pressure cores collected in Hole H005. Herein we focus on lithologic analysis of Hole H002 with the goal of documenting and understanding core recovery in Hole H002 to compare with Hole H005. X-ray Computed Tomography (XCT) images were collected by Geotek on pressurized cores, mostly from Hole H005, and at Ohio State on unpressurized cores, mostly from Hole H002. The XCT images of unpressurized cores show minimal sedimentary structures and layering, unlike the XCT images acquired on the pressurized, hydrate-bearing cores. Only small sections of the unpressurized cores remained intact. The unpressurized cores appear to have two prominent facies: 1) silt that did not retain original sedimentary fabric and often was loose within the core barrel, and 2) dense mud sections with some sedimentary structures and layering present. On the XCT images, drilling mud appears to be concentrated on the sides of cores, but also appears in layers and fractures within intact core sections. On microscope images, the drilling mud also appears to saturate the pores in some silt intervals. Further analysis of the unpressurized cores is planned, including X-ray diffraction, grain size analysis and porosity measurements. These results will be compared to the pressurized cores to understand if further lithologic factors could have affected core recovery.

Simulation of hypervelocity impacts using a contact charge

NASA Astrophysics Data System (ADS)

Giblin, I.; Martelli, G.; Smith, P. N.; di Martino, M.

1994-12-01

Two sets of hypervelocity impact experiments have been performed in the open using a contact charge technique and recorded using fast-framing cameras. It has been possible to record the uninterrupted ballistic trajectories of fragments from the catastrophically disrupted targets, together with their velocity and rotational properties directly after the impact, as well as their size. By performing these experiments in the open and on fairly soft ground, secondary fragmentation normally caused by impact onto the walls or floor of a test chamber has been minimized. A total of 10 experiments have been performed using targets of artificial rock which were either homogeneous, cored or carefully pre-fractured. We report here on the analysis of some of these data using a computer and special software written and developed by our group, with an indication of the results obtained.

Absolute stellar photometry on moderate-resolution FPA images

USGS Publications Warehouse

Stone, T.C.

2009-01-01

An extensive database of star (and Moon) images has been collected by the ground-based RObotic Lunar Observatory (ROLO) as part of the US Geological Survey program for lunar calibration. The stellar data are used to derive nightly atmospheric corrections for the observations from extinction measurements, and absolute calibration of the ROLO sensors is based on observations of Vega and published reference flux and spectrum data. The ROLO telescopes were designed for imaging the Moon at moderate resolution, thus imposing some limitations for the stellar photometry. Attaining accurate stellar photometry with the ROLO image data has required development of specialized processing techniques. A key consideration is consistency in discriminating the star core signal from the off-axis point spread function. The analysis and processing methods applied to the ROLO stellar image database are described. ?? 2009 BIPM and IOP Publishing Ltd.

Development of a neutronics calculation method for designing commercial type Japanese sodium-cooled fast reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Takeda, T.; Shimazu, Y.; Hibi, K.

2012-07-01

Under the R and D project to improve the modeling accuracy for the design of fast breeder reactors the authors are developing a neutronics calculation method for designing a large commercial type sodium- cooled fast reactor. The calculation method is established by taking into account the special features of the reactor such as the use of annular fuel pellet, inner duct tube in large fuel assemblies, large core. The Verification and Validation, and Uncertainty Qualification (V and V and UQ) of the calculation method is being performed by using measured data from the prototype FBR Monju. The results of thismore » project will be used in the design and analysis of the commercial type demonstration FBR, known as the Japanese Sodium fast Reactor (JSFR). (authors)« less

Earliest isotopic evidence in the Maya region for animal management and long-distance trade at the site of Ceibal, Guatemala.

PubMed

Sharpe, Ashley E; Emery, Kitty F; Inomata, Takeshi; Triadan, Daniela; Kamenov, George D; Krigbaum, John

2018-04-03

This study uses a multiisotope (carbon, nitrogen, oxygen, and strontium) approach to examine early animal management in the Maya region. An analysis of faunal specimens across almost 2,000 years (1000 BC to AD 950) at the site of Ceibal, Guatemala, reveals the earliest evidence for live-traded dogs and possible captive-reared taxa in the Americas. These animals may have been procured for ceremonial functions based on their location in the monumental site core, suggesting that animal management and trade began in the Maya area to promote special events, activities that were critical in the development of state society. Isotopic evidence for animal captivity at Ceibal reveals that animal management played a greater role in Maya communities than previously believed. Copyright © 2018 the Author(s). Published by PNAS.

Deep ocean research meets the special education classroom

NASA Astrophysics Data System (ADS)

Turner, A.; Turner, M.; Edwards, K. J.; Scientific Team Of Iodp Expedition 327

2010-12-01

The scientific activities carried out on board the JOIDES Resolution during IODP Expedition 327: Juan de Fuca Hydrogeology (summer 2010) are exciting to elementary-level students and provide an excellent opportunity to use that enthusiasm to teach concepts outlined in state-mandated curricula. This is especially important for special education classrooms where individualized education plans are implemented to bring students up to these standards when regular classrooms have failed to do so. Using concepts from drilling and coring to geobiology and sedimentology, we have developed cross-curricular lesson plans for elementary special education students with learning and cognitive disabilities. All lesson plans include hands-on, visual and auditory activities and are aimed at using students' natural interest in real research to drive home simple concepts like integers, geography, pressure and descriptive writing. Because special education classrooms more often than not include children with variable abilities in all subjects, the lesson plans developed in this project can be adapted for several levels so that every child in the classroom can participate.

Improvement of Speckle Contrast Image Processing by an Efficient Algorithm.

PubMed

Steimers, A; Farnung, W; Kohl-Bareis, M

2016-01-01

We demonstrate an efficient algorithm for the temporal and spatial based calculation of speckle contrast for the imaging of blood flow by laser speckle contrast analysis (LASCA). It reduces the numerical complexity of necessary calculations, facilitates a multi-core and many-core implementation of the speckle analysis and enables an independence of temporal or spatial resolution and SNR. The new algorithm was evaluated for both spatial and temporal based analysis of speckle patterns with different image sizes and amounts of recruited pixels as sequential, multi-core and many-core code.

Schottky barrier parameters and structural properties of rapidly annealed Zr Schottky electrode on p-type GaN

NASA Astrophysics Data System (ADS)

Rajagopal Reddy, V.; Asha, B.; Choi, Chel-Jong

2017-06-01

The Schottky barrier junction parameters and structural properties of Zr/p-GaN Schottky diode are explored at various annealing temperatures. Experimental analysis showed that the barrier height (BH) of the Zr/p-GaN Schottky diode increases with annealing at 400 °C (0.92 eV (I-V)/1.09 eV (C-V)) compared to the as-deposited one (0.83 eV (I-V)/0.93 eV (C-V)). However, the BH decreases after annealing at 500 °C. Also, at different annealing temperatures, the series resistance and BH are assessed by Cheung's functions and their values compared. Further, the interface state density (N SS) of the diode decreases after annealing at 400 °C and then somewhat rises upon annealing at 500 °C. Analysis reveals that the maximum BH is obtained at 400 °C, and thus the optimum annealing temperature is 400 °C for the diode. The XPS and XRD analysis revealed that the increase in BH may be attributed to the creation of Zr-N phases with increasing annealing up to 400 °C. The BH reduces for the diode annealed at 500 °C, which may be due to the formation of Ga-Zr phases at the junction. The AFM measurements reveal that the overall surface roughness of the Zr film is quite smooth during rapid annealing process. Project supported by the R&D Program for Industrial Core Technology (No. 10045216) and the Transfer Machine Specialized Lighting Core Technology Development Professional Manpower Training Project (No. N0001363) Funded by the Ministry of Trade, Industry and Energy (MOTIE), Republic of Korea.

User’s guide to the collection and analysis of tree cores to assess the distribution of subsurface volatile organic compounds

USGS Publications Warehouse

Vroblesky, Don A.

2008-01-01

Analysis of the volatile organic compound content of tree cores is an inexpensive, rapid, simple approach to examining the distribution of subsurface volatile organic compound contaminants. The method has been shown to detect several volatile petroleum hydrocarbons and chlorinated aliphatic compounds associated with vapor intrusion and ground-water contamination. Tree cores, which are approximately 3 inches long, are obtained by using an increment borer. The cores are placed in vials and sealed. After a period of equilibration, the cores can be analyzed by headspace analysis gas chromatography. Because the roots are exposed to volatile organic compound contamination in the unsaturated zone or shallow ground water, the volatile organic compound concentrations in the tree cores are an indication of the presence of subsurface volatile organic compound contamination. Thus, tree coring can be used to detect and map subsurface volatile organic compound contamination. For comparison of tree-core data at a particular site, it is important to maintain consistent methods for all aspects of tree-core collection, handling, and analysis. Factors affecting the volatile organic compound concentrations in tree cores include the type of volatile organic compound, the tree species, the rooting depth, ground-water chemistry, the depth to the contaminated horizon, concentration differences around the trunk related to variations in the distribution of subsurface volatile organic compounds, concentration differences with depth of coring related to volatilization loss through the bark and possibly other unknown factors, dilution by rain, seasonal influences, sorption, vapor-exchange rates, and within-tree volatile organic compound degradation.

Bibliometric study of grey literature in core veterinary medical journals

PubMed Central

Pelzer, Nancy L.; Wiese, William H.

2003-01-01

Objectives: Grey literature has been perceived by many as belonging to the primary sources of information and has become an accepted method of nonconventional communication in the sciences and medicine. Since little is known about the use and nature of grey literature in veterinary medicine, a systematic study was done to analyze and characterize the bibliographic citations appearing in twelve core veterinary journals. Methods: Citations from 2,159 articles published in twelve core veterinary journals in 2000 were analyzed to determine the portion of citations from grey literature. Those citations were further analyzed and categorized according to the type of publication. Results: Citation analysis yielded 55,823 citations, of which 3,564 (6.38%) were considered to be grey literature. Four veterinary specialties, internal medicine, pathology, theriogenology, and microbiology, accounted for 70% of the total number of articles. Three small-animal clinical practice journals cited about 2.5–3% grey literature, less than half that of journals with basic research orientations, where results ranged from almost 6% to approximately 10% grey literature. Nearly 90% of the grey literature appeared as conferences, government publications, and corporate organization literature. Conclusions: The results corroborate other reported research that the incidence of grey literature is lower in medicine and biology than in some other fields, such as aeronautics and agriculture. As in other fields, use of the Internet and the Web has greatly expanded the communication process among veterinary professionals. The appearance of closed community email forums and specialized discussion groups within the veterinary profession is an example of what could become a new kind of grey literature. PMID:14566374

Bibliometric study of grey literature in core veterinary medical journals.

PubMed

Pelzer, Nancy L; Wiese, William H

2003-10-01

Grey literature has been perceived by many as belonging to the primary sources of information and has become an accepted method of nonconventional communication in the sciences and medicine. Since little is known about the use and nature of grey literature in veterinary medicine, a systematic study was done to analyze and characterize the bibliographic citations appearing in twelve core veterinary journals. Citations from 2,159 articles published in twelve core veterinary journals in 2000 were analyzed to determine the portion of citations from grey literature. Those citations were further analyzed and categorized according to the type of publication. Citation analysis yielded 55,823 citations, of which 3,564 (6.38%) were considered to be grey literature. Four veterinary specialties, internal medicine, pathology, theriogenology, and microbiology, accounted for 70% of the total number of articles. Three small-animal clinical practice journals cited about 2.5-3% grey literature, less than half that of journals with basic research orientations, where results ranged from almost 6% to approximately 10% grey literature. Nearly 90% of the grey literature appeared as conferences, government publications, and corporate organization literature. The results corroborate other reported research that the incidence of grey literature is lower in medicine and biology than in some other fields, such as aeronautics and agriculture. As in other fields, use of the Internet and the Web has greatly expanded the communication process among veterinary professionals. The appearance of closed community email forums and specialized discussion groups within the veterinary profession is an example of what could become a new kind of grey literature.

The effects of vortex structure and vortex translation on the tropical cyclone boundary layer wind field

NASA Astrophysics Data System (ADS)

Williams, Gabriel J.

2015-03-01

The effects of vortex translation and radial vortex structure in the distribution of boundary layer winds in the inner core of mature tropical cyclones are examined using a high-resolution slab model and a multilevel model. It is shown that the structure and magnitude of the wind field (and the corresponding secondary circulation) depends sensitively on the radial gradient of the gradient wind field above the boundary layer. Furthermore, it is shown that vortex translation creates low wave number asymmetries in the wind field that rotate anticyclonically with height. A budget analysis of the steady state wind field for both models was also performed in this study. Although the agradient force drives the evolution of the boundary layer wind field for both models, it is shown that the manner in which the boundary layer flow responds to this force differs between the two model representations. In particular, the inner core boundary layer flow in the slab model is dominated by the effects of horizontal advection and horizontal diffusion, leading to the development of shock structures in the model. Conversely, the inner core boundary layer flow in the multilevel model is primarily influenced by the effects of vertical advection and vertical diffusion, which eliminates shock structures in this model. These results further indicate that special care is required to ensure that qualitative applications from slab models are not unduly affected by the neglect of vertical advection. This article was corrected on 31 MAR 2015. See the end of the full text for details.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sen, Ramazan Sonat; Hummel, Andrew John; Hiruta, Hikaru

The deterministic full core simulators require homogenized group constants covering the operating and transient conditions over the entire lifetime. Traditionally, the homogenized group constants are generated using lattice physics code over an assembly or block in the case of prismatic high temperature reactors (HTR). For the case of strong absorbers that causes strong local depressions on the flux profile require special techniques during homogenization over a large volume. Fuel blocks with burnable poisons or control rod blocks are example of such cases. Over past several decades, there have been a tremendous number of studies performed for improving the accuracy ofmore » full-core calculations through the homogenization procedure. However, those studies were mostly performed for light water reactor (LWR) analyses, thus, may not be directly applicable to advanced thermal reactors such as HTRs. This report presents the application of SuPer-Homogenization correction method to a hypothetical HTR core.« less

Simplifying the design of microstructured optical fibre pressure sensors.

PubMed

Osório, Jonas H; Chesini, Giancarlo; Serrão, Valdir A; Franco, Marcos A R; Cordeiro, Cristiano M B

2017-06-07

In this paper, we propose a way to simplify the design of microstructured optical fibres with high sensitivity to applied pressure. The use of a capillary fibre with an embedded core allows the exploration of the pressure-induced material birefringence due to the capillary wall displacements and the photoelastic effect. An analytical description of pressure-induced material birefringence is provided, and fibre modal characteristics are explored through numerical simulations. Moreover, a capillary fibre with an embedded core is fabricated and used to probe pressure variations. Even though the embedded-core fibre has a non-optimized structure, measurements showed a pressure sensitivity of (1.04 ± 0.01) nm/bar, which compares well with more complex, specially designed fibre geometries reported in the literature. These results demonstrate that this geometry enables a novel route towards the simplification of microstructured fibre-based pressure sensors.

Neural evidence that human emotions share core affective properties.

PubMed

Wilson-Mendenhall, Christine D; Barrett, Lisa Feldman; Barsalou, Lawrence W

2013-06-01

Research on the "emotional brain" remains centered around the idea that emotions like fear, happiness, and sadness result from specialized and distinct neural circuitry. Accumulating behavioral and physiological evidence suggests, instead, that emotions are grounded in core affect--a person's fluctuating level of pleasant or unpleasant arousal. A neuroimaging study revealed that participants' subjective ratings of valence (i.e., pleasure/displeasure) and of arousal evoked by various fear, happiness, and sadness experiences correlated with neural activity in specific brain regions (orbitofrontal cortex and amygdala, respectively). We observed these correlations across diverse instances within each emotion category, as well as across instances from all three categories. Consistent with a psychological construction approach to emotion, the results suggest that neural circuitry realizes more basic processes across discrete emotions. The implicated brain regions regulate the body to deal with the world, producing the affective changes at the core of emotions and many other psychological phenomena.

Neural Evidence that Human Emotions Share Core Affective Properties

PubMed Central

Wilson-Mendenhall, Christine D.; Barrett, Lisa Feldman; Barsalou, Lawrence W.

2014-01-01

Research on the “emotional brain” remains centered around the idea that emotions like fear, happiness, and sadness result from specialized and distinct neural circuitry. Accumulating behavioral and physiological evidence suggests, instead, that emotions are grounded in core affect – a person's fluctuating level of pleasant or unpleasant arousal. A neuroimaging study revealed that participants' subjective ratings of valence (i.e., pleasure/displeasure) and of arousal evoked by various fear, happiness, and sadness experiences correlated with neural activity in specific brain regions (orbitofrontal cortex and amygdala, respectively). We observed these correlations across diverse instances within each emotion category, as well as across instances from all three categories. Consistent with a psychological construction approach to emotion, the results suggest that neural circuitry realizes more basic processes across discrete emotions. The implicated brain regions regulate the body to deal with the world, producing the affective changes at the core of emotions and many other psychological phenomena. PMID:23603916

Special series on "The meaning of behavioral medicine in the psychosomatic field" establishment of a core curriculum for behavioral science in Japan: The importance of such a curriculum from the perspective of psychology.

PubMed

Shimazu, Akihito; Nakao, Mutsuhiro

2016-01-01

This article discusses the core curriculum for behavioral science, from the perspective of psychology, recommended by the Japanese Society of Behavioral Medicine and seeks to explain how the curriculum can be effectively implemented in medical and health-related departments. First, the content of the core curriculum is reviewed from the perspective of psychology. We show that the curriculum features both basic and applied components and that the basic components are closely related to various aspects of psychology. Next, we emphasize two points to aid the effective delivery of the curriculum: 1) It is necessary to explain the purpose and significance of basic components of behavioral science to improve student motivation; and 2) it is important to encourage student self-efficacy to facilitate application of the acquired knowledge and skills in clinical practice.

All-fiber orbital angular momentum mode generation and transmission system

NASA Astrophysics Data System (ADS)

Heng, Xiaobo; Gan, Jiulin; Zhang, Zhishen; Qian, Qi; Xu, Shanhui; Yang, Zhongmin

2017-11-01

We proposed and demonstrated an all-fiber system for generating and transmitting orbital angular momentum (OAM) mode light. A specially designed multi-core fiber (MCF) was used to endow with guide modes different phase change and two tapered transition regions were used for providing low-loss interfaces between different fiber structures. By arranging the refractive index distribution among the multi-cores and controlling the length of MCF, which essentially change the phase difference between the neighboring cores, OAM modes with different topological charge l can be generated selectively. Through two tapered transition regions, the non-OAM mode light can be effectively injected into the MCF and the generated OAM mode light can be easily launched into OAM mode supporting fiber for long distance and high purity transmission. Such an all-fiber OAM mode generation and transmission system owns the merits of flexibility, compactness, portability, and would have practical application value in OAM optical fiber communication systems.

Full-spectrum volumetric solar thermal conversion via photonic nanofluids.

PubMed

Liu, Xianglei; Xuan, Yimin

2017-10-12

Volumetric solar thermal conversion is an emerging technique for a plethora of applications such as solar thermal power generation, desalination, and solar water splitting. However, achieving broadband solar thermal absorption via dilute nanofluids is still a daunting challenge. In this work, full-spectrum volumetric solar thermal conversion is demonstrated over a thin layer of the proposed 'photonic nanofluids'. The underlying mechanism is found to be the photonic superposition of core resonances, shell plasmons, and core-shell resonances at different wavelengths, whose coexistence is enabled by the broken symmetry of specially designed composite nanoparticles, i.e., Janus nanoparticles. The solar thermal conversion efficiency can be improved by 10.8% compared with core-shell nanofluids. The extinction coefficient of Janus dimers with various configurations is also investigated to unveil the effects of particle couplings. This work provides the possibility to achieve full-spectrum volumetric solar thermal conversion, and may have potential applications in efficient solar energy harvesting and utilization.

Parallelized Kalman-Filter-Based Reconstruction of Particle Tracks on Many-Core Processors and GPUs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cerati, Giuseppe; Elmer, Peter; Krutelyov, Slava

2017-01-01

For over a decade now, physical and energy constraints have limited clock speed improvements in commodity microprocessors. Instead, chipmakers have been pushed into producing lower-power, multi-core processors such as Graphical Processing Units (GPU), ARM CPUs, and Intel MICs. Broad-based efforts from manufacturers and developers have been devoted to making these processors user-friendly enough to perform general computations. However, extracting performance from a larger number of cores, as well as specialized vector or SIMD units, requires special care in algorithm design and code optimization. One of the most computationally challenging problems in high-energy particle experiments is finding and fitting the charged-particlemore » tracks during event reconstruction. This is expected to become by far the dominant problem at the High-Luminosity Large Hadron Collider (HL-LHC), for example. Today the most common track finding methods are those based on the Kalman filter. Experience with Kalman techniques on real tracking detector systems has shown that they are robust and provide high physics performance. This is why they are currently in use at the LHC, both in the trigger and offine. Previously we reported on the significant parallel speedups that resulted from our investigations to adapt Kalman filters to track fitting and track building on Intel Xeon and Xeon Phi. Here, we discuss our progresses toward the understanding of these processors and the new developments to port the Kalman filter to NVIDIA GPUs.« less

Perceived preparedness for physiatric specialization and future career goals of graduating postgraduate year IV residents during the 2004-2005 academic year.

PubMed

Raj, Vishwa S; Rintala, Diana H

2007-12-01

The purpose of this study was to evaluate trends among postgraduate year (PGY) IV physiatry residents, at the time of graduation from residency, in terms of their perceived experiences in the core clinical areas, confidence with procedural subspecialization, choice in career specialization, and desire to pursue clinical fellowship. Surveys were distributed to 386 PGY IV residents in physiatry at the end of the 2004-2005 academic year. Ninety-three residents (24%) completed responses in a confidential manner. Residents who were generally more confident in core clinical areas, as defined by the Self-Assessment Examination, and specialty prescription writing also believed themselves to be more prepared to practice these topics in their careers. Overall levels of confidence and perceived preparedness correlated positively with months of training and negatively with the belief in the need for postresidency fellowship training to incorporate these areas into clinical practice. Positive correlations also existed among perceived levels of preparedness in performing various physiatric procedures. Statistically significant differences in levels of confidence and preparedness existed among geographic regions when evaluating core physiatric subject matter. Fifty-six percent of residents who responded planned to pursue fellowship training, and a majority of residents intended to perform interventional procedures and musculoskeletal medicine in their practices. These results provide insight into how trainees perceive their current clinical education. With validation of measures for confidence and preparedness, this survey may be useful as an adjunct resource for residency programs to evaluate their trainees.

Parallelized Kalman-Filter-Based Reconstruction of Particle Tracks on Many-Core Processors and GPUs

NASA Astrophysics Data System (ADS)

Cerati, Giuseppe; Elmer, Peter; Krutelyov, Slava; Lantz, Steven; Lefebvre, Matthieu; Masciovecchio, Mario; McDermott, Kevin; Riley, Daniel; Tadel, Matevž; Wittich, Peter; Würthwein, Frank; Yagil, Avi

2017-08-01

For over a decade now, physical and energy constraints have limited clock speed improvements in commodity microprocessors. Instead, chipmakers have been pushed into producing lower-power, multi-core processors such as Graphical Processing Units (GPU), ARM CPUs, and Intel MICs. Broad-based efforts from manufacturers and developers have been devoted to making these processors user-friendly enough to perform general computations. However, extracting performance from a larger number of cores, as well as specialized vector or SIMD units, requires special care in algorithm design and code optimization. One of the most computationally challenging problems in high-energy particle experiments is finding and fitting the charged-particle tracks during event reconstruction. This is expected to become by far the dominant problem at the High-Luminosity Large Hadron Collider (HL-LHC), for example. Today the most common track finding methods are those based on the Kalman filter. Experience with Kalman techniques on real tracking detector systems has shown that they are robust and provide high physics performance. This is why they are currently in use at the LHC, both in the trigger and offine. Previously we reported on the significant parallel speedups that resulted from our investigations to adapt Kalman filters to track fitting and track building on Intel Xeon and Xeon Phi. Here, we discuss our progresses toward the understanding of these processors and the new developments to port the Kalman filter to NVIDIA GPUs.

Characterization Data Package for Containerized Sludge Samples Collected from Engineered Container SCS-CON-210

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fountain, Matthew S.; Fiskum, Sandra K.; Baldwin, David L.

This data package contains the K Basin sludge characterization results obtained by Pacific Northwest National Laboratory during processing and analysis of four sludge core samples collected from Engineered Container SCS-CON-210 in 2010 as requested by CH2M Hill Plateau Remediation Company. Sample processing requirements, analytes of interest, detection limits, and quality control sample requirements are defined in the KBC-33786, Rev. 2. The core processing scope included reconstitution of a sludge core sample distributed among four to six 4-L polypropylene bottles into a single container. The reconstituted core sample was then mixed and subsampled to support a variety of characterization activities. Additionalmore » core sludge subsamples were combined to prepare a container composite. The container composite was fractionated by wet sieving through a 2,000 micron mesh and a 500-micron mesh sieve. Each sieve fraction was sampled to support a suite of analyses. The core composite analysis scope included density determination, radioisotope analysis, and metals analysis, including the Waste Isolation Pilot Plant Hazardous Waste Facility Permit metals (with the exception of mercury). The container composite analysis included most of the core composite analysis scope plus particle size distribution, particle density, rheology, and crystalline phase identification. A summary of the received samples, core sample reconstitution and subsampling activities, container composite preparation and subsampling activities, physical properties, and analytical results are presented. Supporting data and documentation are provided in the appendices. There were no cases of sample or data loss and all of the available samples and data are reported as required by the Quality Assurance Project Plan/Sampling and Analysis Plan.« less

Medical thrillers: doctored fiction for future doctors?

PubMed

Charpy, Jean-Pierre

2014-12-01

Medical thrillers have been a mainstay of popular fiction since the late 1970s and still attract a wide readership today. This article examines this specialized genre and its core conventions within the context of professionally-based fiction, i.e. the class of thrillers written by professionals or former professionals. The author maps this largely unchartered territory and analyzes the fictional representations of doctors and medicine provided in such novels. He argues that medical thrillers, which are not originally aimed at specialized readers and sometimes project a flawed image of medicine, may be used as a pedagogical tool with non-native learners of medical English.

Which future for traumatology in Europe?

PubMed

Rommens, P M

2014-01-01

The last decades have been characterized by rapid changes in society, medicine and surgery. There is a distinct evolution towards specialization and super-specialization. Trauma surgery also evolves towards a specialty, focused on the care of the injured. To optimize the quality of care and meet the needs of patients and care providers, a well-structured trauma surgery training program as well as the regionalization of trauma care with the implementation of Level I trauma centers are needed. The core competence of the European trauma surgeon is the coordination of the early management of the severely injured and the treatment of muskuloskeletal trauma, which represent the most common pathologies in our countries.

Hybrid Text: An Engaging Genre to Teach Content Area Material across the Curriculum

ERIC Educational Resources Information Center

Bintz, William P.; Ciecierski, Lisa M.

2017-01-01

The Common Core State Standards for English language arts expect that teachers will use narrative and informational texts to teach content area material across the curriculum. However, many teachers at all grade levels struggle to incorporate both kinds of text, especially given the vast amount of specialized content they are required to teach.…

77 FR 27783 - National Institute of Neurological Disorders and Stroke Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-11

... Neurological Disorders and Stroke Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory... Disorders and Stroke Special Emphasis Panel, Center Core Grants. Date: June 28, 2012. Time: 8:00 a.m. to 6... Institute of Neurological Disorders and Stroke Initial Review Group, Neurological Sciences and Disorders B...

77 FR 35987 - National Institute of Neurological Disorders and Stroke; Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-15

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Neurological Disorders and Stroke; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Disorders and Stroke Special Emphasis Panel; Center Core Grants. Date: June 28, 2012. Time: 8:00 a.m. to 5...

Joining Forces: Communities and Schools Working Together for a Change. A Special Report.

ERIC Educational Resources Information Center

Rugg, Carol D.

School and community partnerships form the very core of the Mott Foundation, as seen in its founding principles and its varied Civil Society, Flint, and Poverty programs. Although community education has evolved over the years to address increasingly serious problems, the work of today's community organizers is deeply rooted in past theories:…

Visions Lost and Dreams Forgotten: Environmental Education, Systems Thinking, and Possible Futures in American Public Schools

ERIC Educational Resources Information Center

Cassell, John A.; Nelson, Thomas

2010-01-01

This article discusses the contributions to this special issue of "Teacher Education Quarterly." At the core of all the contributions is the compellingly urgent realization that humanity is facing, and must deal with, enormous ecological and social problems and challenges. This situation has created an urgent and compelling need centered…

Method of forming low cost, formable High T(subc) superconducting wire

NASA Technical Reports Server (NTRS)

Smialek, James L. (Inventor)

1989-01-01

A ceramic superconductivity part, such as a wire, is produced through the partial oxidation of a specially formulated copper alloy in a core. The alloys contains low level of quantities of rare earth and alkaline earth dopant elements. Upon oxidation at high temperatures, and superconducting oxide phases are formed as a thin film.

Study on the Competency of Bilingual Art Teachers Based on the Psychology Capital Intervention Model

ERIC Educational Resources Information Center

Li, Donglan

2013-01-01

In this globalization era, it is an important strategy to focus on the core status of bilingual art teachers in the internationalization of higher education. And it is necessary to prepare a thorough, detailed, well-designed assessment criterion for teachers, especially for teachers specialized in art, as their competency relates directly to…

Vocabulary Learning Strategies for Specialized Vocabulary Acquisition: A Case Study.

ERIC Educational Resources Information Center

Lessard-Clouston, Michael

A study investigated and compared the vocabulary learning strategies (VLSs) of five non-native English-speaking and six native English-speaking (NES) graduate students of theology in a core course. The students of English as a Second Language (ESL) were all native speakers of Cantonese or Mandarin Chinese. Specifically, the research explored (1)…

Accessing the Common Core Standards for Students with Learning Disabilities: Strategies for Writing Standards-Based IEP Goals

ERIC Educational Resources Information Center

Caruana, Vicki

2015-01-01

Since the reauthorization of the Individuals With Disabilities Education Act (IDEA) in 2004, standards-based individualized education plans (IEPs) have been an expectation for serving students with disabilities in the K-12 public school setting. Nearly a decade after the mandates calling for standards-based IEPs, special educators still struggle…

Writing IEPs for the Audience of Teachers, Parents, and Students: The Case for the Communicative Individual Education Program

ERIC Educational Resources Information Center

Lucido, Richard J.

2013-01-01

Our current paradigm of Individualized Education Program (IEP) construction, the creation of a legal document or contract between parents and schools, needs rethinking. This paradigm's unintended consequences have resulted in vast inefficiencies in special education and have detracted from the core purpose of the IEP document, the communication of…

Toward the 21st Century: Preparing Proactive Visionary Transformational Leaders for Building Learning Communities. Human Resource Development.

ERIC Educational Resources Information Center

Groff, Warren H.

This package includes a description of Nova University's Human Resource Development (HRD) core seminar and seven doctoral student papers. The description (by Warren Groff) explains how a major curriculum change was made to convert the vocational, technical, and occupational specialization seminar, Personnel-Human Resources Development, to the core…

Health Education Textbook Adoption in Texas: A Lesson in Politics and Morality

ERIC Educational Resources Information Center

Wiley, David; Barr, Elissa

2007-01-01

Textbooks are often a core element of curricula and delivery of classroom instruction and have long been a source of controversy. The textbook adoption process has become less about content and more about political/cultural pressure. Special-interest groups from the right and left exert enormous influence on textbook content through bias and…

Seeking Connection and Coherence in Sport Pedagogy: Minding Gaps and Contemplating a Core

ERIC Educational Resources Information Center

Pope, Clive C.

2014-01-01

Three decades after Daryl Siedentop announced sport pedagogy to be the forgotten sport science, the seven articles in this special issue collectively present sport pedagogy as an emergent field of research and practice. Each contribution presents one or more foci that invite attention to what and how we conduct our research, the political…

Waiver Hopefuls Put through Paces by Review Process

ERIC Educational Resources Information Center

McNeil, Michele

2012-01-01

Before awarding waivers from core tenets of the No Child Left Behind Act to 11 states, the U.S. Department of Education ordered changes to address a significant weakness in most states' proposals: how they would hold schools accountable for groups of students deemed academically at risk, particularly those in special education or learning English.…

The Special Education Core Curriculum Manual, Basic Level. Learning Skills, Oral Language, Reading, Mathematics.

ERIC Educational Resources Information Center

Margolis, Leonard

The manual is designed to serve as a guideline for teachers and child study teams who have the primary responsibility for the education of handicapped children in four areas--learning skills, oral language, reading, and mathematics. Sections for each of the above areas are subdivided into the following objectives and activities: gross motor…

Impact of Enhanced Anchored Instruction in Inclusive Math Classrooms

ERIC Educational Resources Information Center

Bottge, Brian A.; Toland, Michael D.; Gassaway, Linda; Butler, Mark; Choo, Sam; Griffen, Ann Katherine; Ma, Xin

2015-01-01

The Common Core State Standards for Mathematics will place more pressure on special education and math teachers to raise the skill levels of all students, especially those with disabilities in math (MD). The purpose of this study was to assess the effects of enhanced anchored instruction (EAI) on students with and without MD in co-taught general…

Moving Forward: State Engagement with the Next Generation Science Standards. Special re:VISION Insert. Issue 5

ERIC Educational Resources Information Center

Hunt Institute, 2014

2014-01-01

A rigorous K-12 science education builds student knowledge in core scientific content and equips students to analyze problems, use evidence, and investigate solutions. The education requirements of careers across the economy are increasing and all students--regardless of whether they pursue science as a career--need greater proficiency in the…

APPLICATION OF COMPUTER-AIDED TOMOGRAPHY (CAT) AS A POTENTIAL INDICATOR OF MARINE MARCO BENTHIC ACTIVITY ALONG POLLUTION GRADIENTS

EPA Science Inventory

Sediment cores were imaged using a local hospital CAT scanner. These image data were transferred to a personal computer at our laboratory using specially developed software. Previously, we reported an inverse correlation (r2 = 0.98, P<0.01) between the average sediment x-ray atte...

Designing a Course in Statistics for a Learning Health Systems Training Program

ERIC Educational Resources Information Center

Samsa, Gregory P.; LeBlanc, Thomas W.; Zaas, Aimee; Howie, Lynn; Abernethy, Amy P.

2014-01-01

The core pedagogic problem considered here is how to effectively teach statistics to physicians who are engaged in a "learning health system" (LHS). This is a special case of a broader issue--namely, how to effectively teach statistics to academic physicians for whom research--and thus statistics--is a requirement for professional…

A Full Virial Analysis of the Prestellar Cores in the Ophiuchus Molecular Cloud

NASA Astrophysics Data System (ADS)

Pattle, Kate; Ward-Thompson, Derek

We use SCUBA-2, HARP C18O J= 3 -> 2, Herschel and IRAM N2H+ J= 1 -> 0 observations of the Ophiuchus molecular cloud to identify and characterise the properties of the starless cores in the region. The SCUBA-2, HARP and Herschel data were taken as part of the JCMT and Herschel Gould Belt Surveys. We determine masses and temperatures and perform a full virial analysis on our cores, and find that our cores are all either bound or virialised, with gravitational energy and external pressure energy on average of similar importance in confining the cores. There is wide variation from region to region, with cores in the region influenced by B stars (Oph A) being substantially gravitationally bound, and cores in the most quiescent region (Oph C) being pressure-confined. We observe dissipation of turbulence in all our cores, and find that this dissipation is more effective in regions which do not contain outflow-driving protostars. Full details of this analysis are presented by Pattle et al. (2015).

Core Physics and Kinetics Calculations for the Fissioning Plasma Core Reactor

NASA Technical Reports Server (NTRS)

Butler, C.; Albright, D.

2007-01-01

Highly efficient, compact nuclear reactors would provide high specific impulse spacecraft propulsion. This analysis and numerical simulation effort has focused on the technical feasibility issues related to the nuclear design characteristics of a novel reactor design. The Fissioning Plasma Core Reactor (FPCR) is a shockwave-driven gaseous-core nuclear reactor, which uses Magneto Hydrodynamic effects to generate electric power to be used for propulsion. The nuclear design of the system depends on two major calculations: core physics calculations and kinetics calculations. Presently, core physics calculations have concentrated on the use of the MCNP4C code. However, initial results from other codes such as COMBINE/VENTURE and SCALE4a. are also shown. Several significant modifications were made to the ISR-developed QCALC1 kinetics analysis code. These modifications include testing the state of the core materials, an improvement to the calculation of the material properties of the core, the addition of an adiabatic core temperature model and improvement of the first order reactivity correction model. The accuracy of these modifications has been verified, and the accuracy of the point-core kinetics model used by the QCALC1 code has also been validated. Previously calculated kinetics results for the FPCR were described in the ISR report, "QCALC1: A code for FPCR Kinetics Model Feasibility Analysis" dated June 1, 2002.

Synthesis and characterization of lanthanum phosphate nanoparticles as carriers for 223Ra and 225Ra for targeted alpha therapy

DOE PAGES

Rojas, J. V.; Woodward, J. D.; Chen, N.; ...

2015-03-19

Targeted alpha therapy (TAT) has the potential for killing specific tumor cells with minimum collateral damage to surrounding healthy tissue. Radionuclides such as 223Ra, 225Ra, and 225Ac are of special interest for radiotherapeutic applications as they emit multiple -particles during their decay. Utilizing appropriate carriers capable of retaining both the parent radioisotope as well as daughter products is important for the effective delivery of the radioisotope to the tumor site while mitigating global in vivo radiotoxicity. Methods. In this work, core and core+2 shells (NPs with 2 additional layers of cold LaPO 4 deposited on the core surfaces) LaPO4 nanoparticlesmore » (NPs) were synthesized containing either 223Ra or 225Ra/ 225Ac and the retention of the parents and daughters within the NPs in vitro was investigated. Results. The NPs crystallized in rhabdophane phase with mean diameters of 3.4 and 6.3 nm for core and core+2 shells, respectively. The core LaPO 4 NPs retained up to 88% of 223Ra over 35 days. However, in the core+2 shell NPs, the retention of 223Ra and its daughter, 211Pb, was improved to > 99.9% over 27 days. Additionally, the retention of 225Ra/ 225Ac parents was > 99.98% and ~80% for the 221Fr and 213Bi daughters over 35 days for the core+2 shell NPs. Conclusions. These results suggest that LaPO 4 NPs are potentially effective carriers of radium isotopes.« less

Synthesis and characterization of lanthanum phosphate nanoparticles as carriers for 223Ra and 225Ra for targeted alpha therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rojas, J. V.; Woodward, J. D.; Chen, N.

Targeted alpha therapy (TAT) has the potential for killing specific tumor cells with minimum collateral damage to surrounding healthy tissue. Radionuclides such as 223Ra, 225Ra, and 225Ac are of special interest for radiotherapeutic applications as they emit multiple -particles during their decay. Utilizing appropriate carriers capable of retaining both the parent radioisotope as well as daughter products is important for the effective delivery of the radioisotope to the tumor site while mitigating global in vivo radiotoxicity. Methods. In this work, core and core+2 shells (NPs with 2 additional layers of cold LaPO 4 deposited on the core surfaces) LaPO4 nanoparticlesmore » (NPs) were synthesized containing either 223Ra or 225Ra/ 225Ac and the retention of the parents and daughters within the NPs in vitro was investigated. Results. The NPs crystallized in rhabdophane phase with mean diameters of 3.4 and 6.3 nm for core and core+2 shells, respectively. The core LaPO 4 NPs retained up to 88% of 223Ra over 35 days. However, in the core+2 shell NPs, the retention of 223Ra and its daughter, 211Pb, was improved to > 99.9% over 27 days. Additionally, the retention of 225Ra/ 225Ac parents was > 99.98% and ~80% for the 221Fr and 213Bi daughters over 35 days for the core+2 shell NPs. Conclusions. These results suggest that LaPO 4 NPs are potentially effective carriers of radium isotopes.« less

Optofluidic tuning of multimode interference fiber filters

NASA Astrophysics Data System (ADS)

Antonio-Lopez, J. E.; May-Arrioja, D. A.; LiKamWa, P.

2009-05-01

We report on the optofluidic tuning of MMI-based bandpass filters. It is well known that MMI devices exhibit their highest sensitivity when their diameter (D) is modified, since they have a D2 wavelength dependence. In order to increase the MMF diameter we use a special fiber, called No-Core fiber, which is basically a MMF with a diameter of 125 μm with air as the cover. Therefore, when this No-Core fiber is immersed in liquids with different refractive indexes, as a result of the Goes-Hänchen shift the effective width (fundamental mode width) of the No-Core fiber is increased, and thus the peak wavelength is tuned. A tunability of almost 40 nm in going from air (n=1.333) to ethylene glycol (n=1.434) was easily obtained, with a minimum change in peak transmission, contrast, and bandwidth. Moreover, since replacing the entire liquid can be difficult, the device was placed vertically and the liquid was covering the No-Core fiber in small steps. This provided similar amount of tuning as before, but a more controllable tuning mechanism.

Integration of the stratigraphic aspects of very large sea-floor databases using information processing

USGS Publications Warehouse

Jenkins, Clinton N.; Flocks, J.; Kulp, M.; ,

2006-01-01

Information-processing methods are described that integrate the stratigraphic aspects of large and diverse collections of sea-floor sample data. They efficiently convert common types of sea-floor data into database and GIS (geographical information system) tables, visual core logs, stratigraphic fence diagrams and sophisticated stratigraphic statistics. The input data are held in structured documents, essentially written core logs that are particularly efficient to create from raw input datasets. Techniques are described that permit efficient construction of regional databases consisting of hundreds of cores. The sedimentological observations in each core are located by their downhole depths (metres below sea floor - mbsf) and also by a verbal term that describes the sample 'situation' - a special fraction of the sediment or position in the core. The main processing creates a separate output event for each instance of top, bottom and situation, assigning top-base mbsf values from numeric or, where possible, from word-based relative locational information such as 'core catcher' in reference to sampler device, and recovery or penetration length. The processing outputs represent the sub-bottom as a sparse matrix of over 20 sediment properties of interest, such as grain size, porosity and colour. They can be plotted in a range of core-log programs including an in-built facility that better suits the requirements of sea-floor data. Finally, a suite of stratigraphic statistics are computed, including volumetric grades, overburdens, thicknesses and degrees of layering. ?? The Geological Society of London 2006.

Theory and Theorizing in Nursing Science: Commentary from the Nursing Research Special Issue Editorial Team.

PubMed

Jairath, Nalini N; Peden-McAlpine, Cynthia J; Sullivan, Mary C; Vessey, Judith A; Henly, Susan J

Articles from three landmark symposia on theory for nursing-published in Nursing Research in 1968-1969-served as a key underpinning for the development of nursing as an academic discipline. The current special issue on Theory and Theorizing in Nursing Science celebrates the 50th anniversary of publication of these seminal works in nursing theory. The purpose of this commentary is to consider the future of nursing theory development in light of articles published in the anniversary issue. The Editorial Team for the special issue identified core questions about continued nursing theory development, as related to the nursing metaparadigm, practice theory, big data, and doctoral education. Using a dialogue format, the editors discussed these core questions. The classic nursing metaparadigm (health, person, environment, nursing) was viewed as a continuing unifying element for the discipline but is in need of revision in today's scientific and practice climates. Practice theory and precision healthcare jointly arise from an emphasis on individualization. Big data and the methods of e-science are challenging the assumptions on which nursing theory development was originally based. Doctoral education for nursing scholarship requires changes to ensure that tomorrow's scholars are prepared to steward the discipline by advancing (not reifying) past approaches to nursing theory. Ongoing reexamination of theory is needed to clarify the domain of nursing, guide nursing science and practice, and direct and communicate the unique and essential contributions of nursing science to the broader health research effort and of nursing to healthcare.

Best estimate plus uncertainty analysis of departure from nucleate boiling limiting case with CASL core simulator VERA-CS in response to PWR main steam line break event

DOE PAGES

Brown, Cameron S.; Zhang, Hongbin; Kucukboyaci, Vefa; ...

2016-09-07

VERA-CS (Virtual Environment for Reactor Applications, Core Simulator) is a coupled neutron transport and thermal-hydraulics subchannel code under development by the Consortium for Advanced Simulation of Light Water Reactors (CASL). VERA-CS was used to simulate a typical pressurized water reactor (PWR) full core response with 17x17 fuel assemblies for a main steam line break (MSLB) accident scenario with the most reactive rod cluster control assembly stuck out of the core. The accident scenario was initiated at the hot zero power (HZP) at the end of the first fuel cycle with return to power state points that were determined by amore » system analysis code and the most limiting state point was chosen for core analysis. The best estimate plus uncertainty (BEPU) analysis method was applied using Wilks’ nonparametric statistical approach. In this way, 59 full core simulations were performed to provide the minimum departure from nucleate boiling ratio (MDNBR) at the 95/95 (95% probability with 95% confidence level) tolerance limit. The results show that this typical PWR core remains within MDNBR safety limits for the MSLB accident.« less

Best estimate plus uncertainty analysis of departure from nucleate boiling limiting case with CASL core simulator VERA-CS in response to PWR main steam line break event

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, Cameron S.; Zhang, Hongbin; Kucukboyaci, Vefa

VERA-CS (Virtual Environment for Reactor Applications, Core Simulator) is a coupled neutron transport and thermal-hydraulics subchannel code under development by the Consortium for Advanced Simulation of Light Water Reactors (CASL). VERA-CS was used to simulate a typical pressurized water reactor (PWR) full core response with 17x17 fuel assemblies for a main steam line break (MSLB) accident scenario with the most reactive rod cluster control assembly stuck out of the core. The accident scenario was initiated at the hot zero power (HZP) at the end of the first fuel cycle with return to power state points that were determined by amore » system analysis code and the most limiting state point was chosen for core analysis. The best estimate plus uncertainty (BEPU) analysis method was applied using Wilks’ nonparametric statistical approach. In this way, 59 full core simulations were performed to provide the minimum departure from nucleate boiling ratio (MDNBR) at the 95/95 (95% probability with 95% confidence level) tolerance limit. The results show that this typical PWR core remains within MDNBR safety limits for the MSLB accident.« less

Loss of Coolant Accident (LOCA) / Emergency Core Coolant System (ECCS Evaluation of Risk-Informed Margins Management Strategies for a Representative Pressurized Water Reactor (PWR)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Szilard, Ronaldo Henriques

A Risk Informed Safety Margin Characterization (RISMC) toolkit and methodology are proposed for investigating nuclear power plant core, fuels design and safety analysis, including postulated Loss-of-Coolant Accident (LOCA) analysis. This toolkit, under an integrated evaluation model framework, is name LOCA toolkit for the US (LOTUS). This demonstration includes coupled analysis of core design, fuel design, thermal hydraulics and systems analysis, using advanced risk analysis tools and methods to investigate a wide range of results.

An integrative approach to energy, carbon, and redox metabolism in the cyanobacterium Synechocystis sp. PCC 6803

DOE Office of Scientific and Technical Information (OSTI.GOV)

Overbeek, Ross; Fonstein, Veronika; Osterman, Andrei

2005-02-15

The team of the Fellowship for Interpretation of Genomes (FIG) under the leadership of Ross Overbeek, began working on this Project in November 2003. During the previous year, the Project was performed at Integrated Genomics Inc. A transition from the industrial environment to the public domain prompted us to adjust some aspects of the Project. Notwithstanding the challenges, we believe that these adjustments had a strong positive impact on our deliverables. Most importantly, the work of the research team led by R. Overbeek resulted in the deployment of a new open source genomic platform, the SEED (Specific Aim 1). Thismore » platform provided a foundation for the development of CyanoSEED a specialized portal to comparative analysis and metabolic reconstruction of all available cyanobacterial genomes (Specific Aim 3). The SEED represents a new generation of software for genome analysis. Briefly, it is a portable and extendable system, containing one of the largest and permanently growing collections of complete and partial genomes. The complete system with annotations and tools is freely available via browsing or via installation on a user's Mac or Linux computer. One of the important unique features of the SEED is the support of metabolic reconstruction and comparative genome analysis via encoding and projection of functional subsystems. During the project period, the FIG research team has validated the new software by developing a significant number of core subsystems, covering many aspects of central metabolism (Specific Aim 2), as well as metabolic areas specific for cyanobacteria and other photoautotrophic organisms (Specific Aim 3). In addition to providing a proof of technology and a starting point for further community-based efforts, these subsystems represent a valuable asset. An extensive coverage of central metabolism provides the bulk of information required for metabolic modeling in Synechocystis sp.PCC 6803. Detailed analysis of several subsystems covering energy, carbon, and redox metabolism in the Synechocystis sp. PCC 6803 and other cyanobacteria has been performed (Specific Aim 4). The main objectives for this year (adjusted to reflect a new, public domain, setting of the Project research team) were: Aim 1. To develop, test, and deploy a new open source system, the SEED, for integrating community-based annotation, and comparative analysis of all publicly available microbial genomes. Develop a comprehensive genomic database by integrating within SEED all publicly available complete and nearly complete genome sequences with special emphasis on genomes of cyanobacteria, phototrophic eukaryotes, and anoxygenic phototrophic bacteria--invaluable for comparative genomic studies of energy and carbon metabolism in Synechocystis sp. PCC 6803. Aim 2. To develop the SEED's biological content in the form of a collection of encoded Subsystems largely covering the conserved cellular machinery in prokaryotes (and central metabolic machinery in eukaryotes). Aim 3. To develop, utilizing core SEED technology, the CyanoSEED--a specialized WEB portal for community-based annotation, and comparative analysis of all publicly available cyanobacterial genomes. Encode the set of additional subsystems representing key metabolic transformations in cyanobacteria and other photoautotrophs. We envisioned this resource as complementary to other public access databases for comparative genomic analysis currently available to the cyanobacterial research community. Aim 4. Perform in-depth analysis of several subsystems covering energy, carbon, and redox metabolism in the Synechocystis sp. PCC 6803 and all other cyanobacteria with available genome sequences. Reveal inconsistencies and gaps in the current knowledge of these subsystems. Use functional and genome context analysis tools in CyanoSEED to predict, whenever possible, candidate genes for inferred functional roles. To disseminate freely these conjectures and predictions by publishing them on CyanoSEED (http://cyanoseed.thefig.info/) and the Subsystems Forum (http://brucella.uchicago.edu/SubsystemForum/) in order to facilitate experimental analysis by our collaborator on this Project and by other experimentalists working in various field of cyanobacterial physiology and biotechnology.« less

Voltage-spike analysis for a free-running parallel inverter

NASA Technical Reports Server (NTRS)

Lee, F. C. Y.; Wilson, T. G.

1974-01-01

Unwanted and sometimes damaging high-amplitude voltage spikes occur during each half cycle in many transistor saturable-core inverters at the moment when the core saturates and the transistors switch. The analysis shows that spikes are an intrinsic characteristic of certain types of inverters even with negligible leakage inductance and purely resistive load. The small but unavoidable after-saturation inductance of the saturable-core transformer plays an essential role in creating these undesired thigh-voltage spikes. State-plane analysis provides insight into the complex interaction between core and transistors, and shows the circuit parameters upon which the magnitude of these spikes depends.

Glycosylation with ribitol-phosphate in mammals: New insights into the O-mannosyl glycan.

PubMed

Manya, Hiroshi; Endo, Tamao

2017-10-01

O-mannosyl glycans have been found in a limited number of glycoproteins of the brain, nerves, and skeletal muscles, particularly in α-dystroglycan (α-DG). Defects in O-mannosyl glycan on α-DG are the primary cause of a group of congenital muscular dystrophies, which are collectively termed α-dystroglycanopathy. Recent studies have revealed various O-mannosyl glycan structures, which can be classified as core M1, core M2, and core M3 glycans. Although many dystroglycanopathy genes are involved in core M3 processing, the structure and biosynthesis of core M3 glycan remains only partially understood. This review presents recent findings about the structure, biosynthesis, and pathology of O-mannosyl glycans. Recent studies have revealed that the entire structure of core M3 glycan, including ribitol-5-phosphate, is a novel structure in mammals; its unique biosynthetic pathway has been elucidated by the identification of new causative genes for α-dystroglycanopathies and their functions. O-mannosyl glycan has a novel, unique structure that is important for the maintenance of brain and muscle functions. These findings have opened up a new field in glycoscience. These studies will further contribute to the understanding of the pathomechanism of α-dystroglycanopathy and the development of glycotherapeutics. This article is part of a Special Issue entitled Neuro-glycoscience, edited by Kenji Kadomatsu and Hiroshi Kitagawa. Copyright © 2017 Elsevier B.V. All rights reserved.

Particle-in-cell simulation study on halo formation in anisotropic beams

NASA Astrophysics Data System (ADS)

Ikegami, Masanori

2000-11-01

In a recent paper (M. Ikegami, Nucl. Instr. and Meth. A 435 (1999) 284), we investigated halo formation processes in transversely anisotropic beams based on the particle-core model. The effect of simultaneous excitation of two normal modes of core oscillation, i.e., high- and low-frequency modes, was examined. In the present study, self-consistent particle simulations are performed to confirm the results obtained in the particle-core analysis. In these simulations, it is confirmed that the particle-core analysis can predict the halo extent accurately even in anisotropic situations. Furthermore, we find that the halo intensity is enhanced in some cases where two normal modes of core oscillation are simultaneously excited as expected in the particle-core analysis. This result is of practical importance because pure high-frequency mode oscillation has frequently been assumed in preceding halo studies. The dependence of halo intensity on the 2:1 fixed point locations is also discussed.

Damage Tolerance of Sandwich Plates With Debonded Face Sheets

NASA Technical Reports Server (NTRS)

Sankar, Bhavani V.

2001-01-01

A nonlinear finite element analysis was performed to simulate axial compression of sandwich beams with debonded face sheets. The load - end-shortening diagrams were generated for a variety of specimens used in a previous experimental study. The energy release rate at the crack tip was computed using the J-integral, and plotted as a function of the load. A detailed stress analysis was performed and the critical stresses in the face sheet and the core were computed. The core was also modeled as an isotropic elastic-perfectly plastic material and a nonlinear post buckling analysis was performed. A Graeco-Latin factorial plan was used to study the effects of debond length, face sheet and core thicknesses, and core density on the load carrying capacity of the sandwich composite. It has been found that a linear buckling analysis is inadequate in determining the maximum load a debonded sandwich beam can carry. A nonlinear post-buckling analysis combined with an elastoplastic model of the core is required to predict the compression behavior of debonded sandwich beams.

Quantifying the Impact of Nanoparticle Coatings and Non-uniformities on XPS Analysis: Gold/silver Core-shell Nanoparticles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Yung-Chen Andrew; Engelhard, Mark H.; Baer, Donald R.

2016-03-07

Abstract or short description: Spectral modeling of photoelectrons can serve as a valuable tool when combined with X-ray photoelectron spectroscopy (XPS) analysis. Herein, a new version of the NIST Simulation of Electron Spectra for Surface Analysis (SESSA 2.0) software, capable of directly simulating spherical multilayer NPs, was applied to model citrate stabilized Au/Ag-core/shell nanoparticles (NPs). The NPs were characterized using XPS and scanning transmission electron microscopy (STEM) to determine the composition and morphology of the NPs. The Au/Ag-core/shell NPs were observed to be polydispersed in size, non-circular, and contain off-centered Au-cores. Using the average NP dimensions determined from STEM analysis,more » SESSA spectral modeling indicated that washed Au/Ag-core shell NPs were stabilized with a 0.8 nm l« less

A measuring tool for tree-rings analysis

NASA Astrophysics Data System (ADS)

Shumilov, Oleg; Kanatjev, Alexander; Kasatkina, Elena

2013-04-01

A special tool has been created for the annual tree-ring widths measurement and analysis. It consists of professional scanner, computer system and software. This created complex in many aspects does not yield the similar systems (LINTAB, WinDENDRO), but in comparison to manual measurement systems, it offers a number of advantages: productivity gain, possibility of archiving the results of the measurements at any stage of the processing, operator comfort. It has been developed a new software, allowing processing of samples of different types (cores, saw cuts), including those which is difficult to process, having got a complex wood structure (inhomogeneity of growing in different directions, missed, light and false rings etc.). This software can analyze pictures made with optical scanners, analog or digital cameras. The complex software program was created on programming language C++, being compatible with modern operating systems like Windows X. Annual ring widths are measured along paths traced interactively. These paths can have any orientation and can be created so that ring widths are measured perpendicular to ring boundaries. A graphic of ring-widths in function of the year is displayed on a screen during the analysis and it can be used for visual and numerical cross-dating and comparison with other series or master-chronologies. Ring widths are saved to the text files in a special format, and those files are converted to the format accepted for data conservation in the International Tree-Ring Data Bank. The created complex is universal in application that will allow its use for decision of the different problems in biology and ecology. With help of this complex it has been reconstructed a long-term juniper (1328-2004) and pine (1445-2005) tree-ring chronologies on the base of samples collected at Kola Peninsula (northwestern Russia).

Temporal changes in the structure of a plant-frugivore network are influenced by bird migration and fruit availability

PubMed Central

Andresen, Ellen; Díaz-Castelazo, Cecilia

2016-01-01

Background. Ecological communities are dynamic collections whose composition and structure change over time, making up complex interspecific interaction networks. Mutualistic plant–animal networks can be approached through complex network analysis; these networks are characterized by a nested structure consisting of a core of generalist species, which endows the network with stability and robustness against disturbance. Those mutualistic network structures can vary as a consequence of seasonal fluctuations and food availability, as well as the arrival of new species into the system that might disorder the mutualistic network structure (e.g., a decrease in nested pattern). However, there is no assessment on how the arrival of migratory species into seasonal tropical systems can modify such patterns. Emergent and fine structural temporal patterns are adressed here for the first time for plant-frugivorous bird networks in a highly seasonal tropical environment. Methods. In a plant-frugivorous bird community, we analyzed the temporal turnover of bird species comprising the network core and periphery of ten temporal interaction networks resulting from different bird migration periods. Additionally, we evaluated how fruit abundance and richness, as well as the arrival of migratory birds into the system, explained the temporal changes in network parameters such as network size, connectance, nestedness, specialization, interaction strength asymmetry and niche overlap. The analysis included data from 10 quantitative plant-frugivorous bird networks registered from November 2013 to November 2014. Results. We registered a total of 319 interactions between 42 plant species and 44 frugivorous bird species; only ten bird species were part of the network core. We witnessed a noteworthy turnover of the species comprising the network periphery during migration periods, as opposed to the network core, which did not show significant temporal changes in species composition. Our results revealed that migration and fruit richness explain the temporal variations in network size, connectance, nestedness and interaction strength asymmetry. On the other hand, fruit abundance only explained connectance and nestedness. Discussion. By means of a fine-resolution temporal analysis, we evidenced for the first time how temporal changes in the interaction network structure respond to the arrival of migratory species into the system and to fruit availability. Additionally, few migratory bird species are important links for structuring networks, while most of them were peripheral species. We showed the relevance of studying bird–plant interactions at fine temporal scales, considering changing scenarios of species composition with a quantitative network approach. PMID:27330852

"Run-through" training at specialist training year 1 and uncoupled core surgical training for oral and maxillofacial surgery in the United Kingdom: a snapshot survey.

PubMed

Garg, M; Collyer, J; Dhariwal, D

2018-05-01

Training in oral and maxillofacial surgery (OMFS) in the UK has undergone considerable changes during the last 10years, and "core" surgical training has replaced "basic" surgical training. In 2014 a pilot "run-through" training programme from specialist training year one (ST1)-ST7 was introduced to facilitate early entry into the speciality. Run-through training guarantees that a trainee, after a single competitive selection process and satisfactory progress, will be given training that covers the entire curriculum of the speciality, whereas uncoupled training requires a second stage of competitive recruitment after the first one (for OMFS only) or two years of "core" training to progress to higher specialty training. The first two years of run-through training (ST1-ST2) are the same as for core surgical training. Dual-qualified maxillofacial aspirants and those in their second degree course are curious to know whether they should go for the uncoupled core surgical training or the run-through programme in OMFS. The General Medical Council (GMC) has now agreed that run-through training can be rolled out nationally in OMFS. To assess the two pathways we used an online questionnaire to gain feedback about the experience from all OMFS ST3 and run-through trainees (ST3/ST4) in 2016-2017. We identified and contacted 21 trainees, and 17 responded, including seven run-through trainees. Eleven, including five of the run-through trainees, recommended the run-through training programme in OMFS. Six of the seven run-through trainees had studied dentistry first. The overall mean quality of training was rated as 5.5 on a scale 0-10 by the 17 respondents. This survey gives valuable feedback from the current higher surgical trainees in OMFS, which will be useful to the GMC, Health Education England, OMFS Specialist Advisory Committee, and those seeking to enter higher surgical training in OMFS. Copyright © 2018 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

[Regional network for patients with dementia--carrying out Kumamoto model for dementia].

PubMed

Ikeda, Manabu

2014-01-01

The Japanese government has tried to establish 150 Medical Centers for Dementia (MCDs) since 2008 to overcome the dementia medical service shortage. MCDs are required to provide special medical services for dementia and connect with other community resources in order to contribute to building a comprehensive support network for demented patients. The main specific needs are as follows: 1) special medical consultation; 2) differential diagnosis and early intervention; 3) medical treatment for the acute stage of BPSD; 4) corresponding to serious physical complications of dementia; 5) education for general physicians (GPs) and other community professionals. According to the population rate, two dementia medical centers were planned in Kumamoto Prefecture. However, it seemed to be too few to cover the vast Kumamoto area. Therefore, the local government and I proposed to the Japanese government that we build up networks that consist of one core MCD in our university hospital and several regional MCDs in local mental hospitals. The local government selected seven (nine at present) centers according to the area balance and condition of equipment. The Japanese government has recommended and funded such networks between core and regional centers since 2010. The main roles of the core centers are as follows: 1) early diagnosis such as Mild cognitive impairment, very mild Alzheimer's disease, Dementia with Lewy bodies, and Frontotemporal lobar degeneration using comprehensive neuropsychological batteries and neuroimagings, such as MRI and SPECT scans; 2) education for GPs; 3) training for young consultants. The core center opens case conferences at least every one or two months for all staff of regional centers to maintain the quality of all centers and give training opportunities for standardized international assessment scales. While the main roles of the regional centers are differential diagnosis, intervention for BPSD, and management of general medical problems using local networks with general hospitals and GPs, and organizing local networks for dementia with GPs and care staff In short, the regional centers take responsibility for ordinal clinical work for dementia. To construct a more extensive network, each regional center must hold regional case conferences and lectures on dementia for care staff and GPs sharing knowledge and skills acquired from case conferences by the core center.

A pressure core ultrasonic test system for on-board analysis of gas hydrate-bearing sediments under in situ pressures.

PubMed

Yang, Lei; Zhou, Weihua; Xue, Kaihua; Wei, Rupeng; Ling, Zheng

2018-05-01

The enormous potential as an alternative energy resource has made natural gas hydrates a material of intense research interest. Their exploration and sample characterization require a quick and effective analysis of the hydrate-bearing cores recovered under in situ pressures. Here a novel Pressure Core Ultrasonic Test System (PCUTS) for on-board analysis of sediment cores containing gas hydrates at in situ pressures is presented. The PCUTS is designed to be compatible with an on-board pressure core transfer device and a long gravity-piston pressure-retained corer. It provides several advantages over laboratory core analysis including quick and non-destructive detection, in situ and successive acoustic property acquisition, and remission of sample storage and transportation. The design of the unique assembly units to ensure the in situ detection is demonstrated, involving the U-type protecting jackets, transducer precession device, and pressure stabilization system. The in situ P-wave velocity measurements make the detection of gas hydrate existence in the sediments possible on-board. Performance tests have verified the feasibility and sensitivity of the ultrasonic test unit, showing the dependence of P-wave velocity on gas hydrate saturation. The PCUTS has been successfully applied for analysis of natural samples containing gas hydrates recovered from the South China Sea. It is indicated that on-board P-wave measurements could provide a quick and effective understanding of the hydrate occurrence in natural samples, which can assist further resource exploration, assessment, and subsequent detailed core analysis.

A pressure core ultrasonic test system for on-board analysis of gas hydrate-bearing sediments under in situ pressures

NASA Astrophysics Data System (ADS)

Yang, Lei; Zhou, Weihua; Xue, Kaihua; Wei, Rupeng; Ling, Zheng

2018-05-01

The enormous potential as an alternative energy resource has made natural gas hydrates a material of intense research interest. Their exploration and sample characterization require a quick and effective analysis of the hydrate-bearing cores recovered under in situ pressures. Here a novel Pressure Core Ultrasonic Test System (PCUTS) for on-board analysis of sediment cores containing gas hydrates at in situ pressures is presented. The PCUTS is designed to be compatible with an on-board pressure core transfer device and a long gravity-piston pressure-retained corer. It provides several advantages over laboratory core analysis including quick and non-destructive detection, in situ and successive acoustic property acquisition, and remission of sample storage and transportation. The design of the unique assembly units to ensure the in situ detection is demonstrated, involving the U-type protecting jackets, transducer precession device, and pressure stabilization system. The in situ P-wave velocity measurements make the detection of gas hydrate existence in the sediments possible on-board. Performance tests have verified the feasibility and sensitivity of the ultrasonic test unit, showing the dependence of P-wave velocity on gas hydrate saturation. The PCUTS has been successfully applied for analysis of natural samples containing gas hydrates recovered from the South China Sea. It is indicated that on-board P-wave measurements could provide a quick and effective understanding of the hydrate occurrence in natural samples, which can assist further resource exploration, assessment, and subsequent detailed core analysis.

Spatial Variability of Climate Signatures Recorded in an Array of Shallow Firn Cores from the Western Greenland Percolation Zone

NASA Astrophysics Data System (ADS)

Thundercloud, Z. R.; Osterberg, E. C.; Ferris, D. G.; Graeter, K.; Lewis, G.; Hawley, R. L.; Marshall, H. P.

2016-12-01

Greenland ice cores provide seasonally to annually resolved proxy records of past temperature, accumulation and atmospheric circulation. Most Greenland ice cores have been collected from the dry snow zone at elevations greater than 2500 m to produce records of North Atlantic paleoclimate over the last full glacial cycle. Ice cores collected from more costal regions, however, provide the opportunity to develop regional-scale records of climate conditions along ice sheet margins where recent temperature and precipitation changes have been larger than those in the ice sheet interior. These cores are more readily comparable to lake sediment and landscape (i.e. moraine) records from the ice sheet margin, and are potentially more sensitive to sea-ice variability due to the proximity to the coast. Here we present major ion and stable isotope records from an array of firn cores (40-55 year records) collected in the western Greenland percolation zone, and assess the spatial variability of ice core statistical relationships with the North Atlantic Oscillation (NAO) and Baffin Bay sea ice extent. Seven cores were collected from elevations of 2100-2500 m along a 400-km segment of the ice sheet from Dye-2 to Milcent as part of the Greenland Traverse for Accumulation and Climate Studies (GreenTrACS) project from May-June 2016. They were sampled by a continuous melter system at Dartmouth College, and analyzed using Dionex ion chromatographs and a Picarro L2130-i laser ring-down spectrometer. We focus on the signature of the NAO and Baffin Bay sea ice extent in the sea-salt, dust, deuterium excess (d-excess), and methanesulfonic acid (MSA) firn core records, and assess the special variability of these climate-ice core relationships across the study area. Climate reanalysis data indicate that NAO-ice core correlations should be stronger at lower elevation in the percolation zone than high in the dry snow zone. Our results will provide valuable insight into the sensitivity of Greenland ice core paleoclimate reconstructions to the specific ice core location, and thereby aid in site selection for deeper ice cores that could span the Holocene.

Unusual Domain Structure and Filamentary Superfluidity for 2D Hard-Core Bosons in Insulating Charge-Ordered Phase

NASA Astrophysics Data System (ADS)

Panov, Yu. D.; Moskvin, A. S.; Rybakov, F. N.; Borisov, A. B.

2016-12-01

We made use of a special algorithm for compute unified device architecture for NVIDIA graphics cards, a nonlinear conjugate-gradient method to minimize energy functional, and Monte-Carlo technique to directly observe the forming of the ground state configuration for the 2D hard-core bosons by lowering the temperature and its evolution with deviation away from half-filling. The novel technique allowed us to examine earlier implications and uncover novel features of the phase transitions, in particular, look upon the nucleation of the odd domain structure, emergence of filamentary superfluidity nucleated at the antiphase domain walls of the charge-ordered phase, and nucleation and evolution of different topological structures.

Experimental measurement and numerical analysis of group velocity dispersion in cladding modes of an endlessly single-mode photonic crystal fiber

NASA Astrophysics Data System (ADS)

Baselt, Tobias; Taudt, Christopher; Nelsen, Bryan; Lasagni, Andrés. Fabián.; Hartmann, Peter

2017-06-01

The optical properties of the guided modes in the core of photonic crystal fibers (PCFs) can be easily manipulated by changing the air-hole structure in the cladding. Special properties can be achieved in this case such as endless singlemode operation. Endlessly single-mode fibers, which enable single-mode guidance over a wide spectral range, are indispensable in the field of fiber technology. A two-dimensional photonic crystal with a silica central core and a micrometer-spaced hexagonal array of air holes is an established method to achieve endless single-mode properties. In addition to the guidance of light in the core, different cladding modes occur. The coupling between the core and the cladding modes can affect the endlessly single-mode guides. There are two possible ways to determine the dispersion: measurement and calculation. We calculate the group velocity dispersion (GVD) of different cladding modes based on the measurement of the fiber structure parameters, the hole diameter and the pitch of a presumed homogeneous hexagonal array. Based on the scanning electron image, a calculation was made of the optical guiding properties of the microstructured cladding. We compare the calculation with a method to measure the wavelength-dependent time delay. We measure the time delay of defined cladding modes with a homemade supercontinuum light source in a white light interferometric setup. To measure the dispersion of cladding modes of optical fibers with high accuracy, a time-domain white-light interferometer based on a Mach-Zehnder interferometer is used. The experimental setup allows the determination of the wavelengthdependent differential group delay of light travelling through a thirty centimeter piece of test fiber in the wavelength range from VIS to NIR. The determination of the GVD using different methods enables the evaluation of the individual methods for characterizing the cladding modes of an endlessly single-mode fiber.

Tank 241-B-108, cores 172 and 173 analytical results for the final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nuzum, J.L., Fluoro Daniel Hanford

1997-03-04

The Data Summary Table (Table 3) included in this report compiles analytical results in compliance with all applicable DQOS. Liquid subsamples that were prepared for analysis by an acid adjustment of the direct subsample are indicated by a `D` in the A column in Table 3. Solid subsamples that were prepared for analysis by performing a fusion digest are indicated by an `F` in the A column in Table 3. Solid subsamples that were prepared for analysis by performing a water digest are indicated by a I.wl. or an `I` in the A column of Table 3. Due to poormore » precision and accuracy in original analysis of both Lower Half Segment 2 of Core 173 and the core composite of Core 173, fusion and water digests were performed for a second time. Precision and accuracy improved with the repreparation of Core 173 Composite. Analyses with the repreparation of Lower Half Segment 2 of Core 173 did not show improvement and suggest sample heterogeneity. Results from both preparations are included in Table 3.« less

Product competitiveness analysis for e-commerce platform of special agricultural products

NASA Astrophysics Data System (ADS)

Wan, Fucheng; Ma, Ning; Yang, Dongwei; Xiong, Zhangyuan

2017-09-01

On the basis of analyzing the influence factors of the product competitiveness of the e-commerce platform of the special agricultural products and the characteristics of the analytical methods for the competitiveness of the special agricultural products, the price, the sales volume, the postage included service, the store reputation, the popularity, etc. were selected in this paper as the dimensionality for analyzing the competitiveness of the agricultural products, and the principal component factor analysis was taken as the competitiveness analysis method. Specifically, the web crawler was adopted to capture the information of various special agricultural products in the e-commerce platform ---- chi.taobao.com. Then, the original data captured thereby were preprocessed and MYSQL database was adopted to establish the information library for the special agricultural products. Then, the principal component factor analysis method was adopted to establish the analysis model for the competitiveness of the special agricultural products, and SPSS was adopted in the principal component factor analysis process to obtain the competitiveness evaluation factor system (support degree factor, price factor, service factor and evaluation factor) of the special agricultural products. Then, the linear regression method was adopted to establish the competitiveness index equation of the special agricultural products for estimating the competitiveness of the special agricultural products.

Specialized Microbiome of a Halophyte and its Role in Helping Non-Host Plants to Withstand Salinity

PubMed Central

Yuan, Zhilin; Druzhinina, Irina S.; Labbé, Jessy; Redman, Regina; Qin, Yuan; Rodriguez, Russell; Zhang, Chulong; Tuskan, Gerald A.; Lin, Fucheng

2016-01-01

Root microbiota is a crucial determinant of plant productivity and stress tolerance. Here, we hypothesize that the superior halo-tolerance of seepweed Suaeda salsa is tightly linked to a specialized belowground microbiome. To test this hypothesis, we performed a phylogenetic trait-based framework analysis based on bacterial 16S rRNA gene and fungal nuclear rRNA internal transcribed spacer profiling. Data showed that the dominant α-proteobacteria and γ-proteobacteria communities in bulk soil and root endosphere tend to be phylogenetically clustered and at the same time exhibit phylogenetic over-dispersion in rhizosphere. Likewise, the dominant fungal genera occurred at high phylogenetic redundancy. Interestingly, we found the genomes of rhizospheric and endophytic bacteria associated with S. salsa to be enriched in genes contributing to salt stress acclimatization, nutrient solubilization and competitive root colonization. A wide diversity of rhizobacteria with similarity to known halotolerant taxa further supported this interpretation. These findings suggest that an ecological patterned root-microbial interaction strategy has been adopted in S. salsa system to confront soil salinity. We also demonstrated that the potential core microbiome members improve non-host plants growth and salt tolerance. This work provides a platform to improve plant fitness with halophytes-microbial associates and novel insights into the functions of plant microbiome under salinity. PMID:27572178

Heparan sulfate proteoglycans regulate autophagy in Drosophila.

PubMed

Reynolds-Peterson, Claire E; Zhao, Na; Xu, Jie; Serman, Taryn M; Xu, Jielin; Selleck, Scott B

2017-08-03

Heparan sulfate-modified proteoglycans (HSPGs) are important regulators of signaling and molecular recognition at the cell surface and in the extracellular space. Disruption of HSPG core proteins, HS-synthesis, or HS-degradation can have profound effects on growth, patterning, and cell survival. The Drosophila neuromuscular junction provides a tractable model for understanding the activities of HSPGs at a synapse that displays developmental and activity-dependent plasticity. Muscle cell-specific knockdown of HS biosynthesis disrupted the organization of a specialized postsynaptic membrane, the subsynaptic reticulum (SSR), and affected the number and morphology of mitochondria. We provide evidence that these changes result from a dysregulation of macroautophagy (hereafter referred to as autophagy). Cellular and molecular markers of autophagy are all consistent with an increase in the levels of autophagy in the absence of normal HS-chain biosynthesis and modification. HS production is also required for normal levels of autophagy in the fat body, the central energy storage and nutritional sensing organ in Drosophila. Genetic mosaic analysis indicates that HS-dependent regulation of autophagy occurs non-cell autonomously, consistent with HSPGs influencing this cellular process via signaling in the extracellular space. These findings demonstrate that HS biosynthesis has important regulatory effects on autophagy and that autophagy is critical for normal assembly of postsynaptic membrane specializations.

Tank 241-AP-105, cores 208, 209 and 210, analytical results for the final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nuzum, J.L.

1997-10-24

This document is the final laboratory report for Tank 241-AP-105. Push mode core segments were removed from Risers 24 and 28 between July 2, 1997, and July 14, 1997. Segments were received and extruded at 222-S Laboratory. Analyses were performed in accordance with Tank 241-AP-105 Push Mode Core Sampling and Analysis Plan (TSAP) (Hu, 1997) and Tank Safety Screening Data Quality Objective (DQO) (Dukelow, et al., 1995). None of the subsamples submitted for total alpha activity (AT), differential scanning calorimetry (DSC) analysis, or total organic carbon (TOC) analysis exceeded the notification limits as stated in TSAP and DQO. The statisticalmore » results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group, and are not considered in this report. Appearance and Sample Handling Two cores, each consisting of four segments, were expected from Tank 241-AP-105. Three cores were sampled, and complete cores were not obtained. TSAP states core samples should be transported to the laboratory within three calendar days from the time each segment is removed from the tank. This requirement was not met for all cores. Attachment 1 illustrates subsamples generated in the laboratory for analysis and identifies their sources. This reference also relates tank farm identification numbers to their corresponding 222-S Laboratory sample numbers.« less

Drilling the Thuringian Syncline, Germany: core processing during the INFLUINS scientific deep drilling campaign

NASA Astrophysics Data System (ADS)

Abratis, Michael; Methe, Pascal; Aehnelt, Michaela; Kunkel, Cindy; Beyer, Daniel; Kukowski, Nina; Totsche, Kai Uwe

2014-05-01

Deep drilling of the central Thuringian Syncline was carried out in order to gather substantial knowledge of subsurface fluid dynamics and fluid rock interaction within a sedimentary basin. The final depth of the borehole was successfully reached at 1179 m, just a few meters above the Buntsandstein - Zechstein boundary. One of the aspects of the scientific drilling was obtaining sample material from different stratigraphic units for insights in genesis, rock properties and fluid-rock interactions. Parts of the section were cored whereas cuttings provide record of the remaining units. Coring was conducted in aquifers and their surrounding aquitards, i.e. parts of the Upper Muschelkalk (Trochitenkalk), the Middle Muschelkalk, the Upper Buntsandstein (Pelitrot and Salinarrot) and the Middle Buntsandstein. In advance and in cooperation with the GFZ Potsdam team "Scientific Drilling" core handling was discussed and a workflow was developed to ensure efficient and appropriate processing of the valuable core material and related data. Core curation including cleaning, fitting, marking, measuring, cutting, boxing, photographing and unrolled scanning using a DMT core scanner was carried out on the drilling site in Erfurt. Due care was exercised on samples for microbiological analyses. These delicate samples were immediately cut when leaving the core tube and stored within a cooling box at -78°C. Special software for data input was used developed by smartcube GmbH. Advantages of this drilling information system (DIS) are the compatibility with formats of international drilling projects from the IODP and ICDP drilling programs and thus options for exchanges with the international data bases. In a following step, the drill cores were brought to the national core repository of the BGR in Berlin Spandau where the cores were logged for their physical rock properties using a GeoTek multi sensor core logger (MSCL). After splitting the cores into a working and archive half, the cores were scanned for compositional variations using an XRF core scanner at the BGR lab and scan images of the slabbed surfaces were performed. The average core recovery rate was very high at nearly 100%. Altogether, we gained 533 m of excellent core material including sandstones, siltstones and claystones, carbonates, sulfates and chlorides. This provides valuable insight into the stratigraphic column of the Thuringian Syncline.

Special interests and subjective wellbeing in autistic adults.

PubMed

Grove, Rachel; Hoekstra, Rosa A; Wierda, Marlies; Begeer, Sander

2018-05-01

Special interests form part of the core features of autism. However, to date there has been limited research focusing on the role of special interests in the lives of autistic adults. This study surveyed autistic adults on their special interest topics, intensity, and motivation. It also assessed the relationship between special interests and a range of quality of life measures including subjective wellbeing and domain specific life satisfaction. About two thirds of the sample reported having a special interest, with relatively more males reporting a special interest than females. Special interest topics included computers, autism, music, nature and gardening. Most autistic adults engaged in more than one special interest, highlighting that these interests may not be as narrow as previously described. There were no differences in subjective wellbeing between autistic adults with and without special interests. However, for autistic adults who did have special interests, motivation for engaging in special interests was associated with increased subjective wellbeing. This indicates that motivation may play an important role in our understanding of special interests in autism. Special interests had a positive impact on autistic adults and were associated with higher subjective wellbeing and satisfaction across specific life domains including social contact and leisure. However, a very high intensity of engagement with special interests was negatively related to wellbeing. Combined, these findings have important implications for the role of special interests in the lives of autistic adults. Autism Res 2018, 11: 766-775. © 2018 International Society for Autism Research, Wiley Periodicals, Inc. Autistic adults reported having special interests in a range of topics, including computers, music, autism, nature and gardening. Special interests were associated with a number of positive outcomes for autistic adults. They were also related to subjective wellbeing and satisfaction across specific life domains including social contact and leisure. Very high intensity of engagement with special interests was related to lower levels of wellbeing. This highlights the important role that special interests play in the lives of autistic adults. © 2018 International Society for Autism Research, Wiley Periodicals, Inc.

Unfinished business: efforts to define dual-use research of bioterrorism concern.

PubMed

Zmorzynska, Anna; Suk, Jonathan E; Biederbick, Walter; Maidhof, Heinrich; Sasse, Julia; Semenza, Jan C; Hunger, Iris

2011-12-01

Biotechnological research poses a special security problem because of the duality between beneficial use and misuse. In order to find a balance between regulating potentially dangerous research and assuring scientific advancement, a number of assessments have tried to define which types of research are especially open to misuse and should therefore be considered dual-use research of special concern requiring rigorous oversight. So far, there has been no common understanding of what such activities are. Here we present a review of 27 assessments focusing on biological dual-use issues published between 1997 and 2008. Dual-use research activities identified by these assessments as being of special concern were compiled and compared. Moreover, from these 27 assessments, the primary research publications explicitly identified as examples of concerning research activities were extracted and analyzed. We extracted a core list of 11 activities of special concern and show that this list does not match with the reasons why primary research publications were identified as being of special concern. Additionally, we note that the 11 activities identified are not easily conducted or replicated, and therefore the likelihood of their being used in a high-tech mass casualty bioterrorism event should be reevaluated. © Mary Ann Liebert, Inc.

Identification of 526 conserved metazoan genetic innovations exposes a new role for cofactor E-like in neuronal microtubule homeostasis.

PubMed

Frédéric, Melissa Y; Lundin, Victor F; Whiteside, Matthew D; Cueva, Juan G; Tu, Domena K; Kang, S Y Catherine; Singh, Hansmeet; Baillie, David L; Hutter, Harald; Goodman, Miriam B; Brinkman, Fiona S L; Leroux, Michel R

2013-01-01

The evolution of metazoans from their choanoflagellate-like unicellular ancestor coincided with the acquisition of novel biological functions to support a multicellular lifestyle, and eventually, the unique cellular and physiological demands of differentiated cell types such as those forming the nervous, muscle and immune systems. In an effort to understand the molecular underpinnings of such metazoan innovations, we carried out a comparative genomics analysis for genes found exclusively in, and widely conserved across, metazoans. Using this approach, we identified a set of 526 core metazoan-specific genes (the 'metazoanome'), approximately 10% of which are largely uncharacterized, 16% of which are associated with known human disease, and 66% of which are conserved in Trichoplax adhaerens, a basal metazoan lacking neurons and other specialized cell types. Global analyses of previously-characterized core metazoan genes suggest a prevalent property, namely that they act as partially redundant modifiers of ancient eukaryotic pathways. Our data also highlights the importance of exaptation of pre-existing genetic tools during metazoan evolution. Expression studies in C. elegans revealed that many metazoan-specific genes, including tubulin folding cofactor E-like (TBCEL/coel-1), are expressed in neurons. We used C. elegans COEL-1 as a representative to experimentally validate the metazoan-specific character of our dataset. We show that coel-1 disruption results in developmental hypersensitivity to the microtubule drug paclitaxel/taxol, and that overexpression of coel-1 has broad effects during embryonic development and perturbs specialized microtubules in the touch receptor neurons (TRNs). In addition, coel-1 influences the migration, neurite outgrowth and mechanosensory function of the TRNs, and functionally interacts with components of the tubulin acetylation/deacetylation pathway. Together, our findings unveil a conserved molecular toolbox fundamental to metazoan biology that contains a number of neuronally expressed and disease-related genes, and reveal a key role for TBCEL/coel-1 in regulating microtubule function during metazoan development and neuronal differentiation.

Highly stable multi-wall carbon nanotubes@poly(3,4-ethylenedioxythiophene)/poly(styrene sulfonate) core-shell composites with three-dimensional porous nano-network for electrochemical capacitors

NASA Astrophysics Data System (ADS)

Zhou, Haihan; Han, Gaoyi; Chang, Yunzhen; Fu, Dongying; Xiao, Yaoming

2015-01-01

A facile and feasible electrochemical polymerization method has been used to construct the multi-wall carbon nanotubes@poly(3,4-ethylenedioxythiophene)/poly(styrene sulfonate) (MWCNTs@PEDOT/PSS) core-shell composites with three-dimensional (3D) porous nano-network microstructure. The composites are characterized with Fourier transform infrared spectroscopy, scanning electron microscope, and transmission electron microscopy. This special core-shell nanostructure can significantly reduce the ions diffusion distance and the 3D porous nano-network microstructure effectively enlarges the electrode/electrolyte interface. The electrochemical tests including cyclic voltammetry, galvanostatic charge/discharge measurements, and electrochemical impedance spectroscopy tests are performed, the results manifest the MWCNTs@PEDOT/PSS core-shell composites have superior capacitive behaviors and excellent cyclic stability, and a high areal capacitance of 98.1 mF cm-2 is achieved at 5 mV s-1 cyclic voltammetry scan. Furthermore, the MWCNTs@PEDOT/PSS composites exhibit obviously superior capacitive performance than that of PEDOT/PSS and PEDOT/Cl electrodes, indicating the effective composite of MWCNTs and PEDOT noticeably boosts the capacitive performance of PEDOT-based electrodes for electrochemical energy storage. Such a highly stable core-shell 3D network structural composite is very promising to be used as electrode materials for the high-performance electrochemical capacitors.

Overview of Automotive Core Tools: Applications and Benefits

NASA Astrophysics Data System (ADS)

Doshi, Jigar A.; Desai, Darshak

2017-08-01

Continuous improvement of product and process quality is always challenging and creative task in today's era of globalization. Various quality tools are available and used for the same. Some of them are successful and few of them are not. Considering the complexity in the continuous quality improvement (CQI) process various new techniques are being introduced by the industries, as well as proposed by researchers and academia. Lean Manufacturing, Six Sigma, Lean Six Sigma is some of the techniques. In recent years, there are new tools being opted by the industry, especially automotive, called as Automotive Core Tools (ACT). The intention of this paper is to review the applications and benefits along with existing research on Automotive Core Tools with special emphasis on continuous quality improvement. The methodology uses an extensive review of literature through reputed publications—journals, conference proceedings, research thesis, etc. This paper provides an overview of ACT, its enablers, and exertions, how it evolved into sophisticated methodologies and benefits used in organisations. It should be of value to practitioners of Automotive Core Tools and to academics who are interested in how CQI can be achieved using ACT. It needs to be stressed here that this paper is not intended to scorn Automotive Core Tools, rather, its purpose is limited only to provide a balance on the prevailing positive views toward ACT.

Posttest calculations of bundle quench test CORA-13 with ATHLET-CD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bestele, J.; Trambauer, K.; Schubert, J.D.

Gesellschaft fuer Anlagen- und Reaktorsicherheit is developing, in cooperation with the Institut fuer Kernenergetik und Energiesysteme, Stuttgart, the system code Analysis of Thermalhydraulics of Leaks and Transients with Core Degradation (ATHLET-CD). The code consists of detailed models of the thermal hydraulics of the reactor coolant system. This thermo-fluid dynamics module is coupled with modules describing the early phase of the core degradation, like cladding deformation, oxidation and melt relocation, and the release and transport of fission products. The assessment of the code is being done by the analysis of separate effect tests, integral tests, and plant events. The code willmore » be applied to the verification of severe accident management procedures. The out-of-pile test CORA-13 was conducted by Forschungszentrum Karlsruhe in their CORA test facility. The test consisted of two phases, a heatup phase and a quench phase. At the beginning of the quench phase, a sharp peak in the hydrogen generation rate was observed. Both phases of the test have been calculated with the system code ATHLET-CD. Special efforts have been made to simulate the heat losses and the flow distribution in the test facility and the thermal hydraulics during the quench phase. In addition to previous calculations, the material relocation and the quench phase have been modeled. The temperature increase during the heatup phase, the starting time of the temperature escalation, and the maximum temperatures have been calculated correctly. At the beginning of the quench phase, an increased hydrogen generation rate has been calculated as measured in the experiment.« less

Metabolomics analysis: Finding out metabolic building blocks

PubMed Central

2017-01-01

In this paper we propose a new methodology for the analysis of metabolic networks. We use the notion of strongly connected components of a graph, called in this context metabolic building blocks. Every strongly connected component is contracted to a single node in such a way that the resulting graph is a directed acyclic graph, called a metabolic DAG, with a considerably reduced number of nodes. The property of being a directed acyclic graph brings out a background graph topology that reveals the connectivity of the metabolic network, as well as bridges, isolated nodes and cut nodes. Altogether, it becomes a key information for the discovery of functional metabolic relations. Our methodology has been applied to the glycolysis and the purine metabolic pathways for all organisms in the KEGG database, although it is general enough to work on any database. As expected, using the metabolic DAGs formalism, a considerable reduction on the size of the metabolic networks has been obtained, specially in the case of the purine pathway due to its relative larger size. As a proof of concept, from the information captured by a metabolic DAG and its corresponding metabolic building blocks, we obtain the core of the glycolysis pathway and the core of the purine metabolism pathway and detect some essential metabolic building blocks that reveal the key reactions in both pathways. Finally, the application of our methodology to the glycolysis pathway and the purine metabolism pathway reproduce the tree of life for the whole set of the organisms represented in the KEGG database which supports the utility of this research. PMID:28493998

Integration of ANFIS, NN and GA to determine core porosity and permeability from conventional well log data

NASA Astrophysics Data System (ADS)

Ja'fari, Ahmad; Hamidzadeh Moghadam, Rasoul

2012-10-01

Routine core analysis provides useful information for petrophysical study of the hydrocarbon reservoirs. Effective porosity and fluid conductivity (permeability) could be obtained from core analysis in laboratory. Coring hydrocarbon bearing intervals and analysis of obtained cores in laboratory is expensive and time consuming. In this study an improved method to make a quantitative correlation between porosity and permeability obtained from core and conventional well log data by integration of different artificial intelligent systems is proposed. The proposed method combines the results of adaptive neuro-fuzzy inference system (ANFIS) and neural network (NN) algorithms for overall estimation of core data from conventional well log data. These methods multiply the output of each algorithm with a weight factor. Simple averaging and weighted averaging were used for determining the weight factors. In the weighted averaging method the genetic algorithm (GA) is used to determine the weight factors. The overall algorithm was applied in one of SW Iran’s oil fields with two cored wells. One-third of all data were used as the test dataset and the rest of them were used for training the networks. Results show that the output of the GA averaging method provided the best mean square error and also the best correlation coefficient with real core data.

Documentation to the NCES Common Core of Data Public Elementary/Secondary School Universe Survey: School Year 2003-04. NCES 2006-324

ERIC Educational Resources Information Center

Sable, Jennifer; Thomas, Jane Moy; Shen, Quansheng

2006-01-01

The Public Elementary/Secondary School Universe Survey Data provides information about schools such as: type of school (special education, vocational education, charter, magnet); students by grade, race/ethnicity and gender; free lunch eligibility; and classroom teachers. All data are for public elementary and secondary schools for the 2003-04…

The Civic and Political Health of the Nation: A Generational Portrait

ERIC Educational Resources Information Center

Keeter, Scott; Zukin, Cliff; Andolina, Molly; Jenkins, Krista

2002-01-01

This study describes the civic and political behavior of the American public, with a special focus on youth ages 15 to 25. Using an extensive national telephone survey of 3,246 respondents, the authors describe what citizens are doing, and how often they are doing it. They look at a panorama of 19 core activities--ranging from voting to…

Walking the Walk: The Presence of Core Educational Leadership Standards in the Development and Implementation of Partnership Academies

ERIC Educational Resources Information Center

RedCorn, Alex

2016-01-01

In this commentary, the author highlights some of the insights and commentaries of the various stakeholder perspectives contained in this special issue. It was highly apparent that the leaders not only were talking the talk, they were also walking the walk, specifically in the development and implementation of leadership academies. University…

Meeting Professional Competencies through Specialized Distance Education: The McMaster University Addiction Studies Program

ERIC Educational Resources Information Center

Csiernik, Rick; McGaghran, Christie

2013-01-01

Historically, addiction has been an area in which Canadian social workers have received limited formal education. This reality led to the development of 18 core technical competencies through the auspices of the Canadian Centre on Substance Abuse in 2006. A survey of Canadian schools and faculties of social work found that social work students…

Developing a Competency Framework for the Initial Training of Educational Psychologists Working with Young People Aged 16-25

ERIC Educational Resources Information Center

Atkinson, Cathy; Dunsmuir, Sandra; Lang, Jane; Wright, Sarah

2015-01-01

The Children and Families Act (2014) extends statutory protections for young people with special educational needs and disabilities until age 25. Consequently the core curriculum for trainee educational psychologists (TEPs) needs to be developed beyond the current focus of work with early years and school-age children. In order to define requisite…

15 CFR Supplement No. 3 to Part 783 - List of Specified Equipment and Non-Nuclear Material for the Reporting of Imports

Code of Federal Regulations, 2011 CFR

2011-01-01

..., holding or storage vessels for plutonium solutions are designed to avoid criticality problems resulting... windings on a laminated low loss iron core comprised of thin layers typically 2.0 mm (0.08 in) thick or..., and columns with internal turbine mixers), specially designed or prepared for uranium enrichment using...

15 CFR Supplement No. 3 to Part 783 - List of Specified Equipment and Non-Nuclear Material for the Reporting of Imports

Code of Federal Regulations, 2012 CFR

2012-01-01

..., holding or storage vessels for plutonium solutions are designed to avoid criticality problems resulting... windings on a laminated low loss iron core comprised of thin layers typically 2.0 mm (0.08 in) thick or..., and columns with internal turbine mixers), specially designed or prepared for uranium enrichment using...

15 CFR Supplement No. 3 to Part 783 - List of Specified Equipment and Non-Nuclear Material for the Reporting of Imports

Code of Federal Regulations, 2010 CFR

2010-01-01

..., holding or storage vessels for plutonium solutions are designed to avoid criticality problems resulting... windings on a laminated low loss iron core comprised of thin layers typically 2.0 mm (0.08 in) thick or..., and columns with internal turbine mixers), specially designed or prepared for uranium enrichment using...

15 CFR Supplement No. 3 to Part 783 - List of Specified Equipment and Non-Nuclear Material for the Reporting of Imports

Code of Federal Regulations, 2013 CFR

2013-01-01

..., holding or storage vessels for plutonium solutions are designed to avoid criticality problems resulting... windings on a laminated low loss iron core comprised of thin layers typically 2.0 mm (0.08 in) thick or..., and columns with internal turbine mixers), specially designed or prepared for uranium enrichment using...

15 CFR Supplement No. 3 to Part 783 - List of Specified Equipment and Non-Nuclear Material for the Reporting of Imports

Code of Federal Regulations, 2014 CFR

2014-01-01

..., holding or storage vessels for plutonium solutions are designed to avoid criticality problems resulting... windings on a laminated low loss iron core comprised of thin layers typically 2.0 mm (0.08 in) thick or..., and columns with internal turbine mixers), specially designed or prepared for uranium enrichment using...

The Nature of People: Renewing Teacher Education as a Shared Responsibility within Colleges and Schools of Education.

ERIC Educational Resources Information Center

Smith, Garnett J.; Edelen-Smith, Patricia J.

2002-01-01

A survey of 28 National Network for Educational Renewal (NNER) colleges found there was a small core of faculty (21%) who were highly committed to the NNER precept of parity for special education faculty and there was less commitment at the secondary level, particularly for integrated teacher training. (Contains references.) (CR)

Evaluating the Critical Thinking Skills and Academic Characteristics of Undergraduate Students at Two Post-Secondary Institutions Utilizing Two Different Curriculum Models

ERIC Educational Resources Information Center

Hepner, Michael Robert

2012-01-01

This mixed methods study compared the critical thinking skills of students at two post-secondary education institutions that utilize two different curriculum models. A contemporary institution that offers a core curriculum and degree specialization (majors) was contrasted with a Great Books school that utilizes a canon of primary sources and…

Afterschool Supporting Students with Disabilities and Other Special Needs. MetLife Foundation Afterschool Alert. Issue Brief No. 64

ERIC Educational Resources Information Center

Afterschool Alliance, 2014

2014-01-01

The Afterschool Alliance, in partnership with MetLife Foundation, is proud to present the second in their latest series of four issue briefs examining critical issues facing middle school youth and the vital role afterschool programs play in addressing these issues. This series explores afterschool and: the Common Core State Standards, students…

Using CoRes to Develop the Pedagogical Content Knowledge (PCK) of Early Career Science and Technology Teachers

ERIC Educational Resources Information Center

Williams, John; Lockley, John

2012-01-01

Research has shown that one of the factors that enable effective teachers is their rich "Pedagogical Content Knowledge" (PCK), a special blend of content knowledge and pedagogical knowledge that is built up over time and experience. This form of professional knowledge, first theorized by Shulman (1987), is topic-specific, unique to each…

Measurement of 89Y(n,2n) spectral averaged cross section in LR-0 special core reactor spectrum

NASA Astrophysics Data System (ADS)

Košťál, Michal; Losa, Evžen; Baroň, Petr; Šolc, Jaroslav; Švadlenková, Marie; Koleška, Michal; Mareček, Martin; Uhlíř, Jan

2017-12-01

The present paper describes reaction rate measurement of 89Y(n,2n)88Y in a well-defined reactor spectrum of a special core assembled in the LR-0 reactor and compares this value with results of simulation. The reaction rate is derived from the measurement of activity of 88Y using gamma-ray spectrometry of irradiated Y2O3 sample. The resulting cross section value averaged in spectrum is 43.9 ± 1.5 μb, averaged in the 235U spectrum is 0.172 ± 0.006 mb. This cross-section is important as it is used as high energy neutron monitor and is therefore included in the International Reactor Dosimetry and Fusion File. Calculations of reaction rates were performed with the MCNP6 code using ENDF/B-VII.0, JEFF-3.1, JEFF-3.2, JENDL-3.3, JENDL-4, ROSFOND-2010, CENDL-3.1 and IRDFF nuclear data libraries. The agreement with uranium description by CIELO library is very good, while in ENDF/B-VII.0 description of uranium, underprediction about 10% in average can be observed.

VENTURE/PC manual: A multidimensional multigroup neutron diffusion code system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shapiro, A.; Huria, H.C.; Cho, K.W.

1991-12-01

VENTURE/PC is a recompilation of part of the Oak Ridge BOLD VENTURE code system, which will operate on an IBM PC or compatible computer. Neutron diffusion theory solutions are obtained for multidimensional, multigroup problems. This manual contains information associated with operating the code system. The purpose of the various modules used in the code system, and the input for these modules are discussed. The PC code structure is also given. Version 2 included several enhancements not given in the original version of the code. In particular, flux iterations can be done in core rather than by reading and writing tomore » disk, for problems which allow sufficient memory for such in-core iterations. This speeds up the iteration process. Version 3 does not include any of the special processors used in the previous versions. These special processors utilized formatted input for various elements of the code system. All such input data is now entered through the Input Processor, which produces standard interface files for the various modules in the code system. In addition, a Standard Interface File Handbook is included in the documentation which is distributed with the code, to assist in developing the input for the Input Processor.« less

3D Magnetic Field Analysis of a Turbine Generator Stator Core-end Region

NASA Astrophysics Data System (ADS)

Wakui, Shinichi; Takahashi, Kazuhiko; Ide, Kazumasa; Takahashi, Miyoshi; Watanabe, Takashi

In this paper we calculated magnetic flux density and eddy current distributions of a 71MVA turbine generator stator core-end using three-dimensional numerical magnetic field analysis. Subsequently, the magnetic flux densities and eddy current densities in the stator core-end region on the no-load and three-phase short circuit conditions obtained by the analysis have good agreements with the measurements. Furthermore, the differences of eddy current and eddy current loss in the stator core-end region for various load conditions are shown numerically. As a result, the facing had an effect that decrease the eddy current loss of the end plate about 84%.

Project WISH: The Emerald City

NASA Technical Reports Server (NTRS)

Oz, Hayrani; Dunne, Jim; Butchar, Stan; George, Tommy; Hellstrom, Rob; Kringen, Tricia; Owens, George; Perrea, Mike; Semeraro, Paul; Thorndike, Phil

1992-01-01

Phase 3 of Project WISH saw the evolution of the Emerald City (E-City) from a collection of specialized independent analyses and ideas to a working structural design integrated with major support systems and analyses. Emphasis was placed on comparing and contrasting the closed and open cycle gas core nuclear rocket engines to further determine the optimum propulsive system for the E-City. Power and thermal control requirements were then defined and the question of how to meet these requirements was addressed. Software was developed to automate the mission/system/configuration analysis so changes dictated by various subsystem constraints could be managed efficiently and analyzed interactively. In addition, the liquid hydrogen propellant tank was statically designed for minimum mass and shape optimization using a finite element modeling package called SDRC I-DEAS. Spoke and shaft cross-sectional areas were optimized on ASTROS (Automated Structural Optimization System) for mass minimization. A structural dynamic analysis of the optimal structure also conducted using ASTROS enabled a study of the modes, frequencies, displacements, and accelerations of the E-City. Finally, the attitude control system design began with an initial mass moment of inertia analysis and was then designed and optimized using linear quadratic regulator control theory.

[Implementation of Telemedicine in Cape Verde: Influencing Factors].

PubMed

Correia, Artur; Azevedo, Vanda; Lapão, Luís Velez

2017-04-28

Telemedicine is the provision of health services, where distance is a critical factor, using information and communication technologies. Cape Verde has bet on using this tool to increase access of the population of its islands to specialized care. Qualitative study, covering the period between 2013 and 2014. It uses document analysis, semi-structured interviews and focus groups to collect data and analysis of content for their analysis. The participant population includes doctors, nurses and professionals from some institutions related to telemedicine. The priorities of the National Telemedicine Program are set, the cores and reference centers are operational, with trained personnel and equipment installed. Several other policy instruments and conditioning factors and facilitators of the program have been identified. Telemedicine is contributing to the reduction of inequalities in access to health, in Cape Verde. However, the full adoption of a service based on a new technology depends on conditioning factors and facilitators, and several success factors of telemedicine, identified in the literature, are not observed and in conjunction with other existing weaknesses affect the overall development of the National Telemedicine Program. However the strengths and capabilities are highlighted opportunities to act. Despite the progress, some telemedicine success factors highlighted on the literature are not seen in the country.

Project Wish: The Emerald City, phase 3

NASA Technical Reports Server (NTRS)

1992-01-01

Phase 3 of Project Wish saw the evolution of the Emerald City (E-City) from a collection of specialized independent analyses and ideas to a working structural design integrated with major support systems and analyses. Emphasis was placed on comparing and contrasting the closed and open cycle gas core nuclear rocket engines to further determine the optimum propulsive system for the C-City. Power and thermal control requirements were then defined and the question of how to meet these requirements was addressed. Software was developed to automate the mission/system/configuration analysis so changes dictated by various subsystems constraints could be managed efficiently and analyzed interactively. In addition, the liquid hydrogen propellant tank was statically designed for minimum mass and shape optimization using a finite element modeling package called SDRC I-DEAS while spoke and shaft cross-sectional areas were optimized on ASTROS (Automated Structural Optimization System). A structural dynamic analysis also conducted using ASTROS enabled a study of the displacements, accelerations, modes and frequencies of the C-City. Finally, the attitude control system design began with an initial mass moment of inertia analysis and was then designed and optimized using linear quadratic regulator control theory.

An Unexpected Detection of Bifurcated Blue Straggler Sequences in the Young Globular Cluster NGC 2173

NASA Astrophysics Data System (ADS)

Li, Chengyuan; Deng, Licai; de Grijs, Richard; Jiang, Dengkai; Xin, Yu

2018-03-01

The bifurcated patterns in the color–magnitude diagrams of blue straggler stars (BSSs) have attracted significant attention. This type of special (but rare) pattern of two distinct blue straggler sequences is commonly interpreted as evidence that cluster core-collapse-driven stellar collisions are an efficient formation mechanism. Here, we report the detection of a bifurcated blue straggler distribution in a young Large Magellanic Cloud cluster, NGC 2173. Because of the cluster’s low central stellar number density and its young age, dynamical analysis shows that stellar collisions alone cannot explain the observed BSSs. Therefore, binary evolution is instead the most viable explanation of the origin of these BSSs. However, the reason why binary evolution would render the color–magnitude distribution of BSSs bifurcated remains unclear. C. Li, L. Deng, and R. de Grijs jointly designed this project.

Analysis of core-periphery organization in protein contact networks reveals groups of structurally and functionally critical residues.

PubMed

Isaac, Arnold Emerson; Sinha, Sitabhra

2015-10-01

The representation of proteins as networks of interacting amino acids, referred to as protein contact networks (PCN), and their subsequent analyses using graph theoretic tools, can provide novel insights into the key functional roles of specific groups of residues. We have characterized the networks corresponding to the native states of 66 proteins (belonging to different families) in terms of their core-periphery organization. The resulting hierarchical classification of the amino acid constituents of a protein arranges the residues into successive layers - having higher core order - with increasing connection density, ranging from a sparsely linked periphery to a densely intra-connected core (distinct from the earlier concept of protein core defined in terms of the three-dimensional geometry of the native state, which has least solvent accessibility). Our results show that residues in the inner cores are more conserved than those at the periphery. Underlining the functional importance of the network core, we see that the receptor sites for known ligand molecules of most proteins occur in the innermost core. Furthermore, the association of residues with structural pockets and cavities in binding or active sites increases with the core order. From mutation sensitivity analysis, we show that the probability of deleterious or intolerant mutations also increases with the core order. We also show that stabilization centre residues are in the innermost cores, suggesting that the network core is critically important in maintaining the structural stability of the protein. A publicly available Web resource for performing core-periphery analysis of any protein whose native state is known has been made available by us at http://www.imsc.res.in/ ~sitabhra/proteinKcore/index.html.

Advanced Materials and Solids Analysis Research Core (AMSARC)

EPA Science Inventory

The Advanced Materials and Solids Analysis Research Core (AMSARC), centered at the U.S. Environmental Protection Agency's (EPA) Andrew W. Breidenbach Environmental Research Center in Cincinnati, Ohio, is the foundation for the Agency's solids and surfaces analysis capabilities. ...

Determination of power distribution in the VVER-440 core on the basis of data from in-core monitors by means of a metric analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kryanev, A. V.; Udumyan, D. K.; Kurchenkov, A. Yu., E-mail: s327@vver.kiae.ru

2014-12-15

Problems associated with determining the power distribution in the VVER-440 core on the basis of a neutron-physics calculation and data from in-core monitors are considered. A new mathematical scheme is proposed for this on the basis of a metric analysis. In relation to the existing mathematical schemes, the scheme in question improves the accuracy and reliability of the resulting power distribution.

Publications - GMC 385 | Alaska Division of Geological & Geophysical

Science.gov Websites

DGGS GMC 385 Publication Details Title: Porosity, permeability, and capillary pressure core analysis Shimer, G., 2011, Porosity, permeability, and capillary pressure core analysis results (2,124'-2,193 -capilar.xls (108.0 K) gmc385-cores-water.xls (19.0 K) Keywords Oil and Gas; Permeability; Porosity Top of Page

An Interpretative Phenomenological Analysis of the Common Core Standards Program in the State of South Dakota

ERIC Educational Resources Information Center

Alase, Abayomi

2017-01-01

This interpretative phenomenological analysis (IPA) study investigated and interpreted the Common Core State Standards program (the phenomenon) that has been the dominating topic of discussions amongst educators all across the country since the inauguration of the program in 2014/2015 school session. Common Core State Standards (CCSS) was a…

Aqueous poly(amidoamine) dendrimer G3 and G4 generations with several interior cores at pHs 5 and 7: a molecular dynamics simulation study.

PubMed

Kavyani, Sajjad; Amjad-Iranagh, Sepideh; Modarress, Hamid

2014-03-27

Poly(amidoamine) (PAMAM) dendrimers play an important role in drug delivery systems, because the dendrimers are susceptible to gain unique features with modification of their structure such as changing their terminals or improving their interior core. To investigate the core improvement and the effect of core nature on PAMAM dendrimers, we studied two generations G3 and G4 PAMAM dendrimers with the interior cores of commonly used ethylendiamine (EDA), 1,5-diaminohexane (DAH), and bis(3-aminopropyl) ether (BAPE) solvated in water, as an aqueous dendrimer system, by using molecular dynamics simulation and applying a coarse-grained (CG) dendrimer force field. To consider the electrostatic interactions, the simulations were performed at two protonation states, pHs 5 and 7. The results indicated that the core improvement of PAMAM dendrimers with DAH produces the largest size for G3 and G4 dendrimers at both pHs 5 and 7. The increase in the size was also observed for BAPE core but it was not so significant as that for DAH core. By considering the internal structure of dendrimers, it was found that PAMAM dendrimer shell with DAH core had more cavities than with BAPE core at both pHs 5 and 7. Also the moment of inertia calculations showed that the generation G3 is more open-shaped and has higher structural asymmetry than the generation G4. Possessing these properties by G3, specially due to its structural asymmetry, make penetration of water beads into the dendrimer feasible. But for higher generation G4 with its relatively structural symmetry, the encapsulation efficiency for water molecules can be enhanced by changing its core to DAH or BAPE. It is also observed that for the higher generation G4 the effect of core modification is more profound than G3 because the core modification promotes the structural asymmetry development of G4 more significantly. Comparing the number of water beads that penetrate into the PAMAM dendrimers for EDA, DAH, and BAPE cores indicates a significant increase when their cores have been modified with DAH or BAPE and substantiates the effective influence of the core nature in the dendrimer encapsulation efficiency.

Surface integral analogy approaches for predicting noise from 3D high-lift low-noise wings

NASA Astrophysics Data System (ADS)

Yao, Hua-Dong; Davidson, Lars; Eriksson, Lars-Erik; Peng, Shia-Hui; Grundestam, Olof; Eliasson, Peter E.

2014-06-01

Three surface integral approaches of the acoustic analogies are studied to predict the noise from three conceptual configurations of three-dimensional high-lift low-noise wings. The approaches refer to the Kirchhoff method, the Ffowcs Williams and Hawkings (FW-H) method of the permeable integral surface and the Curle method that is known as a special case of the FW-H method. The first two approaches are used to compute the noise generated by the core flow region where the energetic structures exist. The last approach is adopted to predict the noise specially from the pressure perturbation on the wall. A new way to construct the integral surface that encloses the core region is proposed for the first two methods. Considering the local properties of the flow around the complex object-the actual wing with high-lift devices-the integral surface based on the vorticity is constructed to follow the flow structures. The surface location is discussed for the Kirchhoff method and the FW-H method because a common surface is used for them. The noise from the core flow region is studied on the basis of the dependent integral quantities, which are indicated by the Kirchhoff formulation and by the FW-H formulation. The role of each wall component on noise contribution is analyzed using the Curle formulation. Effects of the volume integral terms of Lighthill's stress tensors on the noise prediction are then evaluated by comparing the results of the Curle method with the other two methods.

Information-computational system for storage, search and analytical processing of environmental datasets based on the Semantic Web technologies

NASA Astrophysics Data System (ADS)

Titov, A.; Gordov, E.; Okladnikov, I.

2009-04-01

In this report the results of the work devoted to the development of working model of the software system for storage, semantically-enabled search and retrieval along with processing and visualization of environmental datasets containing results of meteorological and air pollution observations and mathematical climate modeling are presented. Specially designed metadata standard for machine-readable description of datasets related to meteorology, climate and atmospheric pollution transport domains is introduced as one of the key system components. To provide semantic interoperability the Resource Description Framework (RDF, http://www.w3.org/RDF/) technology means have been chosen for metadata description model realization in the form of RDF Schema. The final version of the RDF Schema is implemented on the base of widely used standards, such as Dublin Core Metadata Element Set (http://dublincore.org/), Directory Interchange Format (DIF, http://gcmd.gsfc.nasa.gov/User/difguide/difman.html), ISO 19139, etc. At present the system is available as a Web server (http://climate.risks.scert.ru/metadatabase/) based on the web-portal ATMOS engine [1] and is implementing dataset management functionality including SeRQL-based semantic search as well as statistical analysis and visualization of selected data archives [2,3]. The core of the system is Apache web server in conjunction with Tomcat Java Servlet Container (http://jakarta.apache.org/tomcat/) and Sesame Server (http://www.openrdf.org/) used as a database for RDF and RDF Schema. At present statistical analysis of meteorological and climatic data with subsequent visualization of results is implemented for such datasets as NCEP/NCAR Reanalysis, Reanalysis NCEP/DOE AMIP II, JMA/CRIEPI JRA-25, ECMWF ERA-40 and local measurements obtained from meteorological stations on the territory of Russia. This functionality is aimed primarily at finding of main characteristics of regional climate dynamics. The proposed system represents a step in the process of development of a distributed collaborative information-computational environment to support multidisciplinary investigations of Earth regional environment [4]. Partial support of this work by SB RAS Integration Project 34, SB RAS Basic Program Project 4.5.2.2, APN Project CBA2007-08NSY and FP6 Enviro-RISKS project (INCO-CT-2004-013427) is acknowledged. References 1. E.P. Gordov, V.N. Lykosov, and A.Z. Fazliev. Web portal on environmental sciences "ATMOS" // Advances in Geosciences. 2006. Vol. 8. p. 33 - 38. 2. Gordov E.P., Okladnikov I.G., Titov A.G. Development of elements of web based information-computational system supporting regional environment processes investigations // Journal of Computational Technologies, Vol. 12, Special Issue #3, 2007, pp. 20 - 28. 3. Okladnikov I.G., Titov A.G. Melnikova V.N., Shulgina T.M. Web-system for processing and visualization of meteorological and climatic data // Journal of Computational Technologies, Vol. 13, Special Issue #3, 2008, pp. 64 - 69. 4. Gordov E.P., Lykosov V.N. Development of information-computational infrastructure for integrated study of Siberia environment // Journal of Computational Technologies, Vol. 12, Special Issue #2, 2007, pp. 19 - 30.

GALFIT-CORSAIR: Implementing the Core-Sérsic Model Into GALFIT

NASA Astrophysics Data System (ADS)

Bonfini, Paolo

2014-10-01

We introduce GALFIT-CORSAIR: a publicly available, fully retro-compatible modification of the 2D fitting software GALFIT (v.3) which adds an implementation of the core-Sersic model. We demonstrate the software by fitting the images of NGC 5557 and NGC 5813, which have been previously identified as core-Sersic galaxies by their 1D radial light profiles. These two examples are representative of different dust obscuration conditions, and of bulge/disk decomposition. To perform the analysis, we obtained deep Hubble Legacy Archive (HLA) mosaics in the F555W filter (~V-band). We successfully reproduce the results of the previous 1D analysis, modulo the intrinsic differences between the 1D and the 2D fitting procedures. The code and the analysis procedure described here have been developed for the first coherent 2D analysis of a sample of core-Sersic galaxies, which will be presented in a forth-coming paper. As the 2D analysis provides better constraining on multi-component fitting, and is fully seeing-corrected, it will yield complementary constraints on the missing mass in depleted galaxy cores.

Mapping the literature of diagnostic medical sonography.

PubMed Central

Walcott, B M

1999-01-01

Diagnostic medical sonography has been evolving as a recognized allied health occupation since the early 1970s, but no bibliometric studies of the literature of the field have been published. This study, part of the Medical Library Association Nursing and Allied Health Resources Section's Project for Mapping the Literature of Allied Health, attempted to identify the core journals in diagnostic medical sonography and determine how well these journals are indexed by MEDLINE, EMBASE/Excerpta Medica, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL). Citation analysis was done using the three journals listed for the field by the Brandon/Hill list. Characteristics of two of these three journals affected the results to the extent that more data should be gathered to reach conclusions about the literature of diagnostic medical sonography as a whole. Results of the analysis do suggest that the literature of echocardiography, which is a special area of diagnostic medical sonography, is indexed much more completely by MEDLINE and EMBASE/Excerpta Medica than by CINAHL. Suggestions are made for librarians making collection development decisions in this area of allied health. PMID:10427429

Multicore photonic crystal fiber force meters

NASA Astrophysics Data System (ADS)

Reimlinger, M.; Colalillo, A.; Coompson, J.; Wynne, R.

2011-04-01

A silica based three core photonic crystal fiber (PCF) force meter with fast response times (<30μs) for low wind speed detection is presented. Results are provided for PCF structures containing cores with varied lattice spacing. Force meters with high spatial resolution (sample regions <10cm) specially outfitted for extreme environmental conditions are of interest to both industry and basic research institutions. The featured PCF force meter exhibited sensitivities that agreed with theoretical predictions that are useful for the detection of minimum displacements for wind speeds <30m/s. The results of this investigation are relevant to civil engineering applications including urban sensing technologies that involve air quality monitoring. The deflection of the PCF detection interface was measured as a function of the fiber deflection or the applied force (e.g. wind speed). The three core PCF has a core diameter of 3.9μm, outer diameter of 132.5μm and 7.56μm core-core spacing. A 4cm length of the PCF is attached to the surface of a thin metal beam. One end of the PCF section is fusion spliced to a single mode fiber (SMF) at the fiber input. The remaining fiber end is coupled to a CCD camera with a lens at the PCF output. The applied force deflects the supported PCF such that the intensity distribution of the optical field for the multiple cores changes as a function of displacement. Experimental results from static deflection measurements are in agreement with coupled-mode theory and simple beam deflection theory models.

Brazilian Portuguese version of the CORE-OM: cross-cultural adaptation of an instrument to assess the efficacy and effectiveness of psychotherapy.

PubMed

Santana, Márcia Rosane Moreira; da Silva, Marília Marques; de Moraes, Danielle Souza; Fukuda, Cláudia Cristina; Freitas, Lucia Helena; Ramos, Maria Eveline Cascardo; Fleury, Heloísa Junqueira; Evans, Chris

2015-01-01

The Clinical Outcome in Routine Evaluation - Outcome Measurement (CORE-OM) was developed in the 1990s, with the aim of assessing the efficacy and effectiveness of mental health treatments. To adapt the CORE-OM for use in the Brazilian population. The instrument was translated and adapted based on the international protocol developed by the CORE System Trust which contains seven steps: translation, semantic equivalence analysis, synthesis of the translated versions, pre-testing in the target population, data analysis and back translation. After semantic analysis, modifications were necessary in seven of the 34 original items. Changes were made to avoid repetition of words and the use of terms difficult to understand. Internal consistency analysis showed evidence of score stability in the CORE-OM adapted to Brazilian Portuguese. The instrument was successfully adapted to Brazilian Portuguese, and its semantic and conceptual properties were equivalent to those of the original instrument.

Introduction to special issue: moving forward in pediatric neuropsychology.

PubMed

Daly, Brian P; Giovannetti, Tania; Zabel, T Andrew; Chute, Douglas L

2011-08-01

This special issue of The Clinical Neuropsychologist focuses on advances in the emerging subspecialty of pediatric neuropsychology. The national and international contributions in this issue cover a range of key clinical, research, training, and professional issues specific to pediatric neuropsychology. The genesis for this project developed out of a series of talks at the Philadelphia Pediatric Neuropsychology Symposium in 2010, hosted by the Stein Family Fellow, the Department of Psychology of the College of Arts and Sciences at Drexel University, and the Philadelphia Neuropsychology Society. Articles that explore clinical practice issue focus on the assessment of special medical populations with congenital and/or acquired central nervous system insults. Research articles investigate the core features of developmental conditions, the use of technology in neuropsychological research studies, and large sample size genomic, neuropsychological, and imaging studies of under-represented populations. The final series of articles examine new considerations in training, advocacy, and subspecialty board certification that have emerged in pediatric neuropsychology. This introductory article provides an overview of the articles in this special issue and concluding thoughts about the future of pediatric neuropsychology.

Development of a three-dimensional core dynamics analysis program for commercial boiling water reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bessho, Yasunori; Yokomizo, Osamu; Yoshimoto, Yuichiro

1997-03-01

Development and qualification results are described for a three-dimensional, time-domain core dynamics analysis program for commercial boiling water reactors (BWRs). The program allows analysis of the reactor core with a detailed mesh division, which eliminates calculational ambiguity in the nuclear-thermal-hydraulic stability analysis caused by reactor core regional division. During development, emphasis was placed on high calculational speed and large memory size as attained by the latest supercomputer technology. The program consists of six major modules, namely a core neutronics module, a fuel heat conduction/transfer module, a fuel channel thermal-hydraulic module, an upper plenum/separator module, a feedwater/recirculation flow module, and amore » control system module. Its core neutronics module is based on the modified one-group neutron kinetics equation with the prompt jump approximation and with six delayed neutron precursor groups. The module is used to analyze one fuel bundle of the reactor core with one mesh (region). The fuel heat conduction/transfer module solves the one-dimensional heat conduction equation in the radial direction with ten nodes in the fuel pin. The fuel channel thermal-hydraulic module is based on separated three-equation, two-phase flow equations with the drift flux correlation, and it analyzes one fuel bundle of the reactor core with one channel to evaluate flow redistribution between channels precisely. Thermal margin is evaluated by using the GEXL correlation, for example, in the module.« less

Functional specialization of medial auditory belt cortex in the alert rhesus monkey.

PubMed

Kusmierek, Pawel; Rauschecker, Josef P

2009-09-01

Responses of neural units in two areas of the medial auditory belt (middle medial area [MM] and rostral medial area [RM]) were tested with tones, noise bursts, monkey calls (MC), and environmental sounds (ES) in microelectrode recordings from two alert rhesus monkeys. For comparison, recordings were also performed from two core areas (primary auditory area [A1] and rostral area [R]) of the auditory cortex. All four fields showed cochleotopic organization, with best (center) frequency [BF(c)] gradients running in opposite directions in A1 and MM than in R and RM. The medial belt was characterized by a stronger preference for band-pass noise than for pure tones found medially to the core areas. Response latencies were shorter for the two more posterior (middle) areas MM and A1 than for the two rostral areas R and RM, reaching values as low as 6 ms for high BF(c) in MM and A1, and strongly depended on BF(c). The medial belt areas exhibited a higher selectivity to all stimuli, in particular to noise bursts, than the core areas. An increased selectivity to tones and noise bursts was also found in the anterior fields; the opposite was true for highly temporally modulated ES. Analysis of the structure of neural responses revealed that neurons were driven by low-level acoustic features in all fields. Thus medial belt areas RM and MM have to be considered early stages of auditory cortical processing. The anteroposterior difference in temporal processing indices suggests that R and RM may belong to a different hierarchical level or a different computational network than A1 and MM.

Viewers' perceptions of a YouTube music therapy session video.

PubMed

Gregory, Dianne; Gooding, Lori G

2013-01-01

Recent research revealed diverse content and varying levels of quality in YouTube music therapy videos and prompted questions about viewers' discrimination abilities. This study compares ratings of a YouTube music therapy session video by viewers with different levels of music therapy expertise to determine video elements related to perceptions of representational quality. Eighty-one participants included 25 novices (freshmen and sophomores in an introductory music therapy course), 25 pre-interns (seniors and equivalency students who had completed all core Music Therapy courses), 26 professionals (MT-BC or MT-BC eligibility) with a mean of 1.75 years of experience, and an expert panel of 5 MT-BC professionals with a mean of 11 years of experience in special education. After viewing a music therapy special education video that in previous research met basic competency criteria and professional standards of the American Music Therapy Association, participants completed a 16-item questionnaire. Novices' ratings were more positive (less discriminating) compared to experienced viewers' neutral or negative ratings. Statistical analysis (ANOVA) of novice, pre-intern, and professional ratings of all items revealed significant differences p, .05) for specific therapy content and for a global rating of representational quality. Experienced viewers' ratings were similar to the expert panel's ratings. Content analysis of viewers' reasons for their representational quality ratings corroborated ratings of therapy-specific content. A video that combines and clearly depicts therapy objectives, client improvement, and the effectiveness of music within a therapeutic intervention best represent the music therapy profession in a public social platform like YouTube.

An analysis of teacher’s preparation in implementing 2013 revision edition curriculum on mathematics specialization learning

NASA Astrophysics Data System (ADS)

Susilo, T.; Suryawan, A.

2018-05-01

This study aimed to determine the pedagogical competence of teachers, the readiness of planning and implementation of learning related to the implementation 2013 revised edition curriculum on mathematics specialization learning for senior high schools Wonogiri. Informants in this study there are 6 high school mathematics teachers X and XI class who teach in the school district Wonogiri. Data were collected using questionnaire method, interview, observation and documentation. Qualitative data analysis is done interactively through 4 paths: data collection, data reduction, data display, drawing conclusion. The results showed that high school mathematics teacher class X and XI in school district of Wonogiri City. The results show that most high school mathematics teachers in grade X and XI are ready to implement the 2013 revised edition curriculum and a few have not been able to implement due to internal or external factors. High school math teachers at Wonogiri district who are ready to face the 2013 revised edition curriculum have applied 10 teacher pedagogic competency indicators according to Regulation of the national education ministry Number 16 Year 2007 in learning. The readiness and implementation of mathematics learning is in line with the demands of the 2013 revised edition curriculum. Based on the teachers who are not ready, data on issues that arise in the implementation of the 2013 revised edition curriculum. Especially the problems in learning, namely mismatch of Core Competence (KI) and Basic Competence (KD) in teacher manual, material disregard in student handbook and lack of examples of problems that exist in teacher manual.

Motion of the Mantle in the Translational Modes of the Earth and Mercury

NASA Technical Reports Server (NTRS)

Grinfeld, Pavel; Wisdom, Jack

2005-01-01

Slichter modes refer to the translational motion of the inner core with respect to the outer core and the mantle. The polar Slichter mode is the motion of the inner core along the axis of rotation. Busse presented an analysis of the polar mode which yielded an expression for its period. Busse's analysis included the assumption that the mantle was stationary. This approximation is valid for planets with small inner cores, such as the Earth whose inner core is about 1/60 of the total planet mass. On the other hand, many believe that Mercury's core may be enormous. If so, the motion of the mantle should be expected to produce a significant effect. We present a formal framework for including the motion of the mantle in the analysis of the translational motion of the inner core. We analyze the effect of the motion of the mantle on the Slichter modes for a non-rotating planet with an inner core of arbitrary size. We omit the effects of viscosity in the outer core, magnetic effects, and solid tides. Our approach is perturbative and is based on a linearization of Euler's equations for the motion of the fluid and Newton's second law for the motion of the inner core. We find an analytical expression for the period of the Slichter mode. Our result agrees with Busse's in the limiting case of small inner core. We present the unexpected result that even for Mercury the motion of the mantle does not significantly change the period of oscillation.

A New Capability for Nuclear Thermal Propulsion Design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Amiri, Benjamin W.; Nuclear and Radiological Engineering Department, University of Florida, Gainesville, FL 32611; Kapernick, Richard J.

2007-01-30

This paper describes a new capability for Nuclear Thermal Propulsion (NTP) design that has been developed, and presents the results of some analyses performed with this design tool. The purpose of the tool is to design to specified mission and material limits, while maximizing system thrust to weight. The head end of the design tool utilizes the ROCket Engine Transient Simulation (ROCETS) code to generate a system design and system design requirements as inputs to the core analysis. ROCETS is a modular system level code which has been used extensively in the liquid rocket engine industry for many years. Themore » core design tool performs high-fidelity reactor core nuclear and thermal-hydraulic design analysis. At the heart of this process are two codes TMSS-NTP and NTPgen, which together greatly automate the analysis, providing the capability to rapidly produce designs that meet all specified requirements while minimizing mass. A PERL based command script, called CORE DESIGNER controls the execution of these two codes, and checks for convergence throughout the process. TMSS-NTP is executed first, to produce a suite of core designs that meet the specified reactor core mechanical, thermal-hydraulic and structural requirements. The suite of designs consists of a set of core layouts and, for each core layout specific designs that span a range of core fuel volumes. NTPgen generates MCNPX models for each of the core designs from TMSS-NTP. Iterative analyses are performed in NTPgen until a reactor design (fuel volume) is identified for each core layout that meets cold and hot operation reactivity requirements and that is zoned to meet a radial core power distribution requirement.« less

Special Purpose Nuclear Reactor (5 MW) for Reliable Power at Remote Sites Assessment Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sterbentz, James William; Werner, James Elmer; McKellar, Michael George

The Phenomena Identification and Ranking Table (PIRT) technique was conducted on the Special Purpose Reactor nuclear plant design. The PIRT is a structured process to identify safety-relevant/safety-significant phenomena and assess the importance and knowledge base by ranking the phenomena. The Special Purpose Reactor is currently in the conceptual design stage. The candidate reactor has a solid monolithic stainless steel core with an array of heat pipes and fuel pellets embedded in the monolith. The heat pipes are used to remove heat from the core using simple, reliable, and well-characterized physics (capillarity, boiling, and condensation). In the initial design, one heatmore » exchanger is used for the working fluid that produces energy, and a second heat exchanger is used to remove decay heat in emergency or shutdown conditions. In addition, a power conversion cycle such as an open-air Brayton system is available as an option for power conversion and process heat. This report summarizes and documents the process and scope of the four PIRT reviews, noting the major activities and conclusions. The identified phenomena, analyses, rationales, and associated ratings are presented along with a summary of the findings from the four individual PIRTs, namely (1) Reactor Accident and Normal Operations, (2) Heat Pipes, (3) Materials, and (4) Power Conversion. The PIRT reports for these four major system areas evaluated are attached as appendixes to this report and provide considerably more detail about each assessment as well as a more complete listing of the phenomena that were evaluated.« less

A counter-rotating vortex pair in inviscid fluid

NASA Astrophysics Data System (ADS)

Habibah, Ummu; Fukumoto, Yasuhide

2017-12-01

We study the motion of a counter-rotating vortex pair with the circulations ±Γ move in incompressible fluid. The assumption is made that the core is very thin, that is the core radius σ is much smaller than the vortex radius d such that ɛ = σ/d ≪ 1. With this condition, the method of matched asymptotic expansion is employed. The solutions of the Navier-Stokes equations and the Biot-Savart law, regarding the inner and outer solutions respectively, are constructed in the form of a small parameter. An asymptotic expansion of the Biot-Savart law near the vortex core provides with the matching condition for an asymptotic expansion for limiting the Navier-Stokes equations for large radius r. The general formula of an anti-parallel vortex pair is established. At leading order O(ɛ0), we apply the special case in inviscid fluid, the Rankine vortex, a circular vortex of uniform vorticity. Furthermore at leading order O(ɛ5) we show the traveling speed of a vortex pair.

Hollow-core photonic-crystal-fiber-based optical frequency references

NASA Astrophysics Data System (ADS)

Holá, Miroslava; Hrabina, Jan; Mikel, Břetislav; Lazar, Josef; Číp, Ondřej

2016-12-01

This research deals with preparation of an optical frequency references based on hollow-core photonic crystal fibers (HC-PCF). This fiber-based type of absorption cells represents a effiecient way how to replace classic bulky and fragile glass made tubes references with low-weight and low-volume optical fibers. This approach allows not only to increase possible interaction length between incident light and absorption media but it also carries a possibility of manufacturing of easy-operable reference which is set up just by plugging-in of optical connectors into the optical setup. We present the results of preparation, manufacturing and filling of a set of fiber-based cells intended for lasers frequency stabilization. The work deals with setting and optimalization of HC-PCF splicing processes, minimalization of optical losses between HC-PCF and SMF fiber transitions and finishing of HC-PCF spliced ends with special care for optimal closing of hollow-core structure needed for avoiding of absorption media leakage.

Highly luminescent core-shell InP/ZnX (X = S, Se) quantum dots prepared via a phosphine synthetic route.

PubMed

Mordvinova, Natalia; Vinokurov, Alexander; Kuznetsova, Tatiana; Lebedev, Oleg I; Dorofeev, Sergey

2017-01-24

Here we report a simple method for the creation of highly luminescent core-shell InP/ZnX (X = S, Se) quantum dots (QDs) on the basis of a phosphine synthetic route. In this method a Zn precursor was added to the reaction mixture at the beginning of the synthesis to form an In(Zn)P alloy structure, which promoted the formation of a ZnX shell. Core-shell InP/ZnX QDs exhibit highly intensive emission with a quantum yield over 50%. The proposed method is primarily important for practical applications. Advantages of this method compared to the widely used SILAR technique are discussed. We further demonstrate that the SILAR approach consisting of consequent addition of Zn and chalcogen precursors to pre-prepared non-doped InP colloidal nanoparticles is not quite suitable for shell growth without the addition of special activator agents or the use of very reactive precursors.