Sample records for specially designed experimental

  1. 34 CFR 461.33 - What are special experimental demonstration projects and teacher training projects?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false What are special experimental demonstration projects...? § 461.33 What are special experimental demonstration projects and teacher training projects? (a) In... personnel in programs designed to carry out the purposes of the Act; and (ii) Training professional teachers...

  2. 34 CFR 461.33 - What are special experimental demonstration projects and teacher training projects?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What are special experimental demonstration projects...? § 461.33 What are special experimental demonstration projects and teacher training projects? (a) In... personnel in programs designed to carry out the purposes of the Act; and (ii) Training professional teachers...

  3. 34 CFR 461.33 - What are special experimental demonstration projects and teacher training projects?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false What are special experimental demonstration projects...? § 461.33 What are special experimental demonstration projects and teacher training projects? (a) In... personnel in programs designed to carry out the purposes of the Act; and (ii) Training professional teachers...

  4. 34 CFR 461.33 - What are special experimental demonstration projects and teacher training projects?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What are special experimental demonstration projects...? § 461.33 What are special experimental demonstration projects and teacher training projects? (a) In... personnel in programs designed to carry out the purposes of the Act; and (ii) Training professional teachers...

  5. 34 CFR 461.33 - What are special experimental demonstration projects and teacher training projects?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false What are special experimental demonstration projects...? § 461.33 What are special experimental demonstration projects and teacher training projects? (a) In... personnel in programs designed to carry out the purposes of the Act; and (ii) Training professional teachers...

  6. The 1988 Get Away Special Experimenter's Symposium

    NASA Technical Reports Server (NTRS)

    Thomas, Lawrence R. (Editor); Mosier, Frances L. (Editor)

    1988-01-01

    The Get Away Special (GAS) Experimenter's Symposium was held to provide a formal opportunity for GAS experimenters to share the results of their projects. The focus of this symposium is on payloads that have been flown on shuttle missions and on GAS payloads that will be flown in the future. Experiment design and payload integration issues are also examined.

  7. 26 CFR 1.263A-2 - Rules relating to property produced by the taxpayer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the incurring of significant expenditures for property of specialized design or specialized... costs incurred by publishers in writing, editing, compiling, illustrating, designing, and developing the... provides that the term research or experimental expenditures does not include expenditures incurred for...

  8. 26 CFR 1.263A-2 - Rules relating to property produced by the taxpayer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... the incurring of significant expenditures for property of specialized design or specialized... costs incurred by publishers in writing, editing, compiling, illustrating, designing, and developing the... provides that the term research or experimental expenditures does not include expenditures incurred for...

  9. 26 CFR 1.263A-2 - Rules relating to property produced by the taxpayer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... the incurring of significant expenditures for property of specialized design or specialized... costs incurred by publishers in writing, editing, compiling, illustrating, designing, and developing the... provides that the term research or experimental expenditures does not include expenditures incurred for...

  10. 26 CFR 1.263A-2 - Rules relating to property produced by the taxpayer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the incurring of significant expenditures for property of specialized design or specialized... costs incurred by publishers in writing, editing, compiling, illustrating, designing, and developing the... provides that the term research or experimental expenditures does not include expenditures incurred for...

  11. 26 CFR 1.263A-2 - Rules relating to property produced by the taxpayer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the incurring of significant expenditures for property of specialized design or specialized... costs incurred by publishers in writing, editing, compiling, illustrating, designing, and developing the... provides that the term research or experimental expenditures does not include expenditures incurred for...

  12. Proceedings of the Symposium on Psychology in the Department of Defense (8th) Held in Colorado Springs, Colorado on 21-23 April 1982

    DTIC Science & Technology

    1982-12-01

    readily visible but still represent low level flight. 33 Experimental Design and Pc,cedures. The experimental design used in this study was a 3 X 2...October 1979. Winer, B.J. Statistical principles in experimental design . New York: McGraw-Hill, 1971. 47 NONTRADITIONAL ADMISSIONS FACTORS: THE SPECIAL...Quasi- Experimental Designs for Research. Chicago: Rand McNally, 1963. R.C. Carter and H. Sbisa. Human Performance tests for repeated measurements

  13. El Paso/Yslete schools Get-Away Special Space Shuttle student projects

    NASA Technical Reports Server (NTRS)

    Azar, S. S.

    1984-01-01

    Student projects for the Get Away Special (GAS) space shuttle program were summarized. Experimental topics included: seed germination, shrimp growth, liquid lasers, planaria regeneration, fluid dynamics (wicking), soil molds, antibiotics, crystallization, the symbiosis of yeast and fungi, and the performance of electronic chips. A brief experimental design is included for each project.

  14. Methods of Microcomputer Research in Early Childhood Special Education.

    ERIC Educational Resources Information Center

    Fujiura, Glenn; Johnson, Lawrence J.

    1986-01-01

    The review of some recent studies on use of microcomputers in early childhood special education highlights methodological issues including the qualitative quantitative distinction and the interdependence of research design and interpretation. Imbedding qualitative methods into quasi- or true-experimental designs can provide more information than…

  15. 47 CFR 74.436 - Special requirements for automatic relay stations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL...) An automatic relay station must be designed, installed, and protected so that the transmitter can...

  16. 47 CFR 74.436 - Special requirements for automatic relay stations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL...) An automatic relay station must be designed, installed, and protected so that the transmitter can...

  17. 47 CFR 74.436 - Special requirements for automatic relay stations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL...) An automatic relay station must be designed, installed, and protected so that the transmitter can...

  18. 47 CFR 74.436 - Special requirements for automatic relay stations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL...) An automatic relay station must be designed, installed, and protected so that the transmitter can...

  19. 47 CFR 74.436 - Special requirements for automatic relay stations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL...) An automatic relay station must be designed, installed, and protected so that the transmitter can...

  20. Work Program. Fiscal Year 1972 for The Department of the Army. Research and Development in Training, Motivation, and Leadership

    DTIC Science & Technology

    1971-07-01

    itself. IlumRRO assistance was requested by the Infantry School both for design of experimental tests and for analysis and interpretation of the data from...of Research. To develop an experimental Army literacy training program designed to provide a level of functional literacy appropriate to present...assigned under the provisions of a long- range program (up to two years in duration) designed by tlumRRO. Specially designed experimental

  1. Effects of Training in Universal Design for Learning on Lesson Plan Development

    ERIC Educational Resources Information Center

    Spooner, Fred; Baker, Joshua N.; Harris, Amber A.; Ahlgrim-Delzell, Lynn; Browder, Diane M.

    2007-01-01

    The effects of training in Universal Design for Learning (UDL) on lesson plan development of special and general educators in a college classroom environment were investigated. A true experimental group design with a control group was used for this study. A one-hour teacher training session introduced UDL to the experimental group; the control…

  2. 45 CFR 260.76 - What special rules apply to States that are continuing evaluations of their waiver demonstrations?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... demonstrations? If a State is continuing research that employs an experimental design in order to complete an impact evaluation of a waiver demonstration, the experimental and control groups may continue to be... 45 Public Welfare 2 2013-10-01 2012-10-01 true What special rules apply to States that are...

  3. 45 CFR 260.76 - What special rules apply to States that are continuing evaluations of their waiver demonstrations?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... demonstrations? If a State is continuing research that employs an experimental design in order to complete an impact evaluation of a waiver demonstration, the experimental and control groups may continue to be... 45 Public Welfare 2 2014-10-01 2012-10-01 true What special rules apply to States that are...

  4. Estimation of sample size and testing power (Part 3).

    PubMed

    Hu, Liang-ping; Bao, Xiao-lei; Guan, Xue; Zhou, Shi-guo

    2011-12-01

    This article introduces the definition and sample size estimation of three special tests (namely, non-inferiority test, equivalence test and superiority test) for qualitative data with the design of one factor with two levels having a binary response variable. Non-inferiority test refers to the research design of which the objective is to verify that the efficacy of the experimental drug is not clinically inferior to that of the positive control drug. Equivalence test refers to the research design of which the objective is to verify that the experimental drug and the control drug have clinically equivalent efficacy. Superiority test refers to the research design of which the objective is to verify that the efficacy of the experimental drug is clinically superior to that of the control drug. By specific examples, this article introduces formulas of sample size estimation for the three special tests, and their SAS realization in detail.

  5. Replication of Special Education Research: Necessary but Far Too Rare

    ERIC Educational Resources Information Center

    Makel, Matthew C.; Plucker, Jonathan A.; Freeman, Jennifer; Lombardi, Allison; Simonsen, Brandi; Coyne, Michael

    2016-01-01

    Increased calls for rigor in special education have often revolved around the use of experimental research design. However, the replicability of research results is also a central tenet to the scientific research process. To assess the prevalence, success rate, and authorship history of replications in special education, we investigated the…

  6. Design, Specification and Construction of Specialized Measurement System in the Experimental Building

    NASA Astrophysics Data System (ADS)

    Fedorczak-Cisak, Malgorzata; Kwasnowski, Pawel; Furtak, Marcin; Hayduk, Grzegorz

    2017-10-01

    Experimental buildings for “in situ” research are a very important tool for collecting data on energy efficiency of the energy-saving technologies. One of the most advanced building of this type in Poland is the Maloposkie Laboratory of Energy-saving Buildings at Cracow University of Technology. The building itself is used by scientists as a research object and research tool to test energy-saving technologies. It is equipped with a specialized measuring system consisting of approx. 3 000 different sensors distributed in technical installations and structural elements of the building (walls, ceilings, cornices) and the ground. The authors of the paper will present the innovative design and technology of this specialized instrumentation. They will discuss issues arising during the implementation and use of the building.

  7. Impact of the Design of U.S. History Textbooks on Content Acquisition and Academic Engagement of Special Education Students: An Experimental Investigation

    ERIC Educational Resources Information Center

    Harniss, Mark K.; Caros, Jennifer; Gersten, Russell

    2007-01-01

    We used randomized controlled trials to compare the impact of the designs of 2 United States history textbooks on the content acquisition and behavior of 8th-grade students identified for special education services or identified as low achieving. We also investigated whether teachers differed in their use of instructional activities and…

  8. 45 CFR 260.76 - What special rules apply to States that are continuing evaluations of their waiver demonstrations?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... demonstrations? If a State is continuing research that employs an experimental design in order to complete an impact evaluation of a waiver demonstration, the experimental and control groups may continue to be...

  9. 45 CFR 260.76 - What special rules apply to States that are continuing evaluations of their waiver demonstrations?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... demonstrations? If a State is continuing research that employs an experimental design in order to complete an impact evaluation of a waiver demonstration, the experimental and control groups may continue to be...

  10. 45 CFR 260.76 - What special rules apply to States that are continuing evaluations of their waiver demonstrations?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... demonstrations? If a State is continuing research that employs an experimental design in order to complete an impact evaluation of a waiver demonstration, the experimental and control groups may continue to be...

  11. 14 CFR 183.31 - Designated manufacturing inspection representatives.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... airworthiness approvals for engines, propellers, and product parts that conform to the approved design... airworthiness approval tags in accordance with subpart L of part 21 of this chapter; (3) Experimental... changes to the type design requiring a flight test; and (4) Special flight permits to export aircraft. (b...

  12. 14 CFR 183.31 - Designated manufacturing inspection representatives.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... airworthiness approvals for engines, propellers, and product parts that conform to the approved design... airworthiness approval tags in accordance with subpart L of part 21 of this chapter; (3) Experimental... changes to the type design requiring a flight test; and (4) Special flight permits to export aircraft. (b...

  13. 14 CFR 183.31 - Designated manufacturing inspection representatives.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... airworthiness approvals for engines, propellers, and product parts that conform to the approved design... airworthiness approval tags in accordance with subpart L of part 21 of this chapter; (3) Experimental... changes to the type design requiring a flight test; and (4) Special flight permits to export aircraft. (b...

  14. 14 CFR 183.31 - Designated manufacturing inspection representatives.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... airworthiness approvals for engines, propellers, and product parts that conform to the approved design... airworthiness approval tags in accordance with subpart L of part 21 of this chapter; (3) Experimental... changes to the type design requiring a flight test; and (4) Special flight permits to export aircraft. (b...

  15. 14 CFR 183.31 - Designated manufacturing inspection representatives.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... airworthiness approvals for engines, propellers, and product parts that conform to the approved design... airworthiness approval tags in accordance with subpart L of part 21 of this chapter; (3) Experimental... changes to the type design requiring a flight test; and (4) Special flight permits to export aircraft. (b...

  16. Effects of a Professional Development Package to Prepare Special Education Paraprofessionals to Implement Evidence-Based Practice

    ERIC Educational Resources Information Center

    Brock, Matthew E.; Carter, Erik W.

    2015-01-01

    Although paraprofessionals have become an increasingly integral part of special education services, most paraprofessionals lack training in evidence-based instructional strategies. We used a randomized contolled experimental design to examine the efficacy of a professional development training package and its individual components to equip 25…

  17. Culturally Responsive Experimental Intervention Studies: The Development of a Rubric for Paradigm Expansion

    ERIC Educational Resources Information Center

    Bal, Aydin; Trainor, Audrey A.

    2016-01-01

    Neither legislative demand for evidence-based practices nor a focus on experimental designs for educational interventions has ameliorated the disparate educational opportunities and outcomes for youth from nondominant cultural and linguistic backgrounds. Recent initiatives to increase the rigor of intervention research in special education have…

  18. Children's Experimental Workshop: Expanding the Park Experience to Children with Special Needs.

    ERIC Educational Resources Information Center

    Ross, Wendy, Ed.; And Others

    The handbook was designed to assist those interested in developing accessible programs for the handicapped in a variety of settings - parks, recreational areas, community centers, and other cultural and educational facilities - by providing information on how the Children's Experimental Workshop (CEW) was created, implemented, and evaluated. The…

  19. A Modified Experimental Hut Design for Studying Responses of Disease-Transmitting Mosquitoes to Indoor Interventions: The Ifakara Experimental Huts

    PubMed Central

    Okumu, Fredros O.; Moore, Jason; Mbeyela, Edgar; Sherlock, Mark; Sangusangu, Robert; Ligamba, Godfrey; Russell, Tanya; Moore, Sarah J.

    2012-01-01

    Differences between individual human houses can confound results of studies aimed at evaluating indoor vector control interventions such as insecticide treated nets (ITNs) and indoor residual insecticide spraying (IRS). Specially designed and standardised experimental huts have historically provided a solution to this challenge, with an added advantage that they can be fitted with special interception traps to sample entering or exiting mosquitoes. However, many of these experimental hut designs have a number of limitations, for example: 1) inability to sample mosquitoes on all sides of huts, 2) increased likelihood of live mosquitoes flying out of the huts, leaving mainly dead ones, 3) difficulties of cleaning the huts when a new insecticide is to be tested, and 4) the generally small size of the experimental huts, which can misrepresent actual local house sizes or airflow dynamics in the local houses. Here, we describe a modified experimental hut design - The Ifakara Experimental Huts- and explain how these huts can be used to more realistically monitor behavioural and physiological responses of wild, free-flying disease-transmitting mosquitoes, including the African malaria vectors of the species complexes Anopheles gambiae and Anopheles funestus, to indoor vector control-technologies including ITNs and IRS. Important characteristics of the Ifakara experimental huts include: 1) interception traps fitted onto eave spaces and windows, 2) use of eave baffles (panels that direct mosquito movement) to control exit of live mosquitoes through the eave spaces, 3) use of replaceable wall panels and ceilings, which allow safe insecticide disposal and reuse of the huts to test different insecticides in successive periods, 4) the kit format of the huts allowing portability and 5) an improved suite of entomological procedures to maximise data quality. PMID:22347415

  20. A Comparison of Burnout among Honors, Regular Education, and Special Education K-8 Teachers

    ERIC Educational Resources Information Center

    Sharpe, Christopher

    2017-01-01

    This study employed a quantitative, ex-post facto non-experimental design to examine the effect of whether teaching honors, regular, or special education classes in either an elementary or middle school setting influenced the experience of teacher burnout. Participants included 69 teachers from two counties in a Southern state. The study survey…

  1. Dutch Research on Knowledge-Based Instructional Systems: Introduction to the Special Issue.

    ERIC Educational Resources Information Center

    van Merrienboer, Jeroen J. G.

    1994-01-01

    Provides an overview of this issue that reviews Dutch research concerning knowledge-based instructional systems. Topics discussed include experimental research, conceptual models, design considerations, and guidelines; the design of student diagnostic modules, instructional modules, and interface modules; second-language teaching; intelligent…

  2. 47 CFR 74.655 - Authorization of equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES Television Broadcast... and regulations. (f) Transmitters designed to be used exclusively for a TV STL station, a TV intercity...

  3. Experimental setup for investigation of two-phase (water-air) flows in a tube

    NASA Astrophysics Data System (ADS)

    Kazunin, D. V.; Lashkov, V. A.; Mashek, I. Ch.; Khoronzhuk, R. S.

    2018-05-01

    A special setup was designed and built at St. Petersburg State University for providing experimental research in flow dynamics of the of air-water mixtures in a pipeline. The test section of the setup allows simulating a wide range of flow regimes of a gas-liquid mixture. The parameters of the experimental setup are given; the initial test results are discussed.

  4. Instruction: Cable and Slow-Scan. Workshop.

    ERIC Educational Resources Information Center

    Pachuta, Jack

    The Rockford Cable Project is an experimental program using two-way cable television to train firefighters in prefire planning. The instructional design calls for firefighters across the city to view videotapes simultaneously and respond to computerized questions via a specially-designed pushbutton terminal. The project provides for centralized…

  5. Status of Single-Case Research Designs for Evidence-Based Practice

    ERIC Educational Resources Information Center

    Matson, Johnny L.; Turygin, Nicole C.; Beighley, Jennifer; Matson, Michael L.

    2012-01-01

    The single-case research design has become a paradoxical methodology in the applied sciences. While various experimental designs have been in place for over 50 years, there has not been wide acceptance of single-case methodology outside clinical and school psychology, or the field of special education. These methods were developed in the U.S.A.,…

  6. 47 CFR 74.533 - Remote control and unattended operation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES Aural Broadcast... designed, installed, and protected so that the transmitter can only be activated or controlled by persons...

  7. 47 CFR 74.533 - Remote control and unattended operation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES Aural Broadcast... designed, installed, and protected so that the transmitter can only be activated or controlled by persons...

  8. 47 CFR 74.1250 - Transmitters and associated equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES FM Broadcast... designed to operate. The apparatus shall be equipped with suitable meters or meter jacks so that the...

  9. 47 CFR 74.533 - Remote control and unattended operation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES Aural Broadcast... designed, installed, and protected so that the transmitter can only be activated or controlled by persons...

  10. Co-Teaching and Collaboration: Preservice Teachers' Knowledge, Attitudes, and Perceived Sense of Efficacy in Teaching Students with Disabilities

    ERIC Educational Resources Information Center

    Bowlin, Tamara M.; Bell, Sherry Mee; Coleman, Mari Beth; Cihak, David F.

    2015-01-01

    A quasi-experimental design and multiple regression analysis were used to examine responses of 153 preservice general and special education teachers as a function of (a) participation in an introductory special education course and (b) viewing a co-teaching video (Friend, 2005) versus observing an inclusive classroom. Based on responses to pre-…

  11. Space-filling designs for computer experiments: A review

    DOE PAGES

    Joseph, V. Roshan

    2016-01-29

    Improving the quality of a product/process using a computer simulator is a much less expensive option than the real physical testing. However, simulation using computationally intensive computer models can be time consuming and therefore, directly doing the optimization on the computer simulator can be infeasible. Experimental design and statistical modeling techniques can be used for overcoming this problem. This article reviews experimental designs known as space-filling designs that are suitable for computer simulations. In the review, a special emphasis is given for a recently developed space-filling design called maximum projection design. Furthermore, its advantages are illustrated using a simulation conductedmore » for optimizing a milling process.« less

  12. Space-filling designs for computer experiments: A review

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Joseph, V. Roshan

    Improving the quality of a product/process using a computer simulator is a much less expensive option than the real physical testing. However, simulation using computationally intensive computer models can be time consuming and therefore, directly doing the optimization on the computer simulator can be infeasible. Experimental design and statistical modeling techniques can be used for overcoming this problem. This article reviews experimental designs known as space-filling designs that are suitable for computer simulations. In the review, a special emphasis is given for a recently developed space-filling design called maximum projection design. Furthermore, its advantages are illustrated using a simulation conductedmore » for optimizing a milling process.« less

  13. Using SimCPU in Cooperative Learning Laboratories.

    ERIC Educational Resources Information Center

    Lin, Janet Mei-Chuen; Wu, Cheng-Chih; Liu, Hsi-Jen

    1999-01-01

    Reports research findings of an experimental design in which cooperative-learning strategies were applied to closed-lab instruction of computing concepts. SimCPU, a software package specially designed for closed-lab usage was used by 171 high school students of four classes. Results showed that collaboration enhanced learning and that blending…

  14. Medical experiments on persons with special needs, a comparative study of Islamic jurisprudence vs. Arab laws: UAE law as case study.

    PubMed

    Hammad, Hamza Abed Al-Karim

    2014-01-01

    This article is a comparative study of medical experiments on persons with special needs in Islamic jurisprudence and Arab laws; United Arab Emirates (UAE) law as case study. The current study adopts a comparative analytical and descriptive approach. The conclusion of this study points out that the Convention on the Rights of Persons with Special Needs, ratified by a number of Arab States, including the United Arab Emirates, approves conducting medical experiments on persons with special needs, subject to their free consent. As a result of ratifying this Convention, a number of special laws were enacted to be enforced in the United Arab Emirates. On the other hand, this issue is controversial from an Islamic jurisprudence point of view. One group of jurisprudents permits conducting these experimentations if they are designed to treat the person involved, and prohibits such experimentations for scientific advancement. Other jurisprudents permit conducting medical experimentations on persons with special needs, whether the purpose of such experimentations is treatment of the disabled or achieving scientific advancement. The opinion of this group is consistent with the International Convention and the Arab laws in this respect. However, neither the Convention nor the Arab laws regulate this matter by specific and comprehensive conditions, as addressed by some contemporary scholars. It is recommended that the Convention and the Arab laws adopt these conditions. Additionally, the Convention does not state whether the experimentations may be conducted for the interest of the person with disability or for the purpose of scientific advancement. The text of the Convention is unclear and therefore requires further illumination.

  15. DoD Key Technologies Plan

    DTIC Science & Technology

    1992-07-01

    methodologies ; software performance analysis; software testing; and concurrent languages. Finally, efforts in algorithms, which are primarily designed to upgrade...These codes provide a powerful research tool for testing new concepts and designs prior to experimental implementation. DoE’s laser program has also...development, and specially designed production facilities. World leadership in bth non -fluorinated and fluorinated materials resides in the U.S. but Japan

  16. 47 CFR 74.733 - UHF translator signal boosters.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV.... Care shall be taken in the design of the apparatus to insure that out-of-band radiation is not...

  17. Microteaching and Pre-Service Teachers' Sense of Self-Efficacy in Teaching

    ERIC Educational Resources Information Center

    Arsal, Zeki

    2014-01-01

    This study examined the effect of microteaching on pre-service teachers' sense of self-efficacy in teaching using a pre-test/post-test quasi-experimental design. The sample of the study consisted of 70 pre-service teachers on a special education teacher preparation programme. The pre-service teachers in the experimental group were exposed to…

  18. The Effects of Infant Day Care on Psychological Development.

    ERIC Educational Resources Information Center

    Kagan, Jerome; And Others

    This is a partial report of a longitudinal investigation designed to assess the psychological effects of an experimentally conducted day care program on children during the first 30 months of life. The experimental subjects were Chinese and Caucasian children from working and middle class families who were cared for at a special group care center…

  19. 47 CFR 74.795 - Digital low power TV and TV translator transmission system facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (CONTINUED) BROADCAST RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM... transmitter shall be designed to produce digital television signals that can be satisfactorily viewed on...., average power over a 6 MHz channel) and shall be designed to prevent the power output from exceeding the...

  20. 47 CFR 74.795 - Digital low power TV and TV translator transmission system facilities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (CONTINUED) BROADCAST RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM... transmitter shall be designed to produce digital television signals that can be satisfactorily viewed on...., average power over a 6 MHz channel) and shall be designed to prevent the power output from exceeding the...

  1. 47 CFR 74.795 - Digital low power TV and TV translator transmission system facilities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... (CONTINUED) BROADCAST RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM... transmitter shall be designed to produce digital television signals that can be satisfactorily viewed on...., average power over a 6 MHz channel) and shall be designed to prevent the power output from exceeding the...

  2. 47 CFR 74.795 - Digital low power TV and TV translator transmission system facilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (CONTINUED) BROADCAST RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM... transmitter shall be designed to produce digital television signals that can be satisfactorily viewed on...., average power over a 6 MHz channel) and shall be designed to prevent the power output from exceeding the...

  3. 47 CFR 74.795 - Digital low power TV and TV translator transmission system facilities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... (CONTINUED) BROADCAST RADIO SERVICES EXPERIMENTAL RADIO, AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM... transmitter shall be designed to produce digital television signals that can be satisfactorily viewed on...., average power over a 6 MHz channel) and shall be designed to prevent the power output from exceeding the...

  4. A Professional Learning Program for Enhancing the Competency of Students with Special Needs

    ERIC Educational Resources Information Center

    Kantavong, Pennee; Sivabaedya, Suwaree

    2010-01-01

    This study used a quasi-experimental research design to examine the impact of a professional learning program designed to enhance the competency of children with Autism, Attention Deficit Hyperactivity Disorder and Learning Disabilities and to develop knowledge, understanding and skills of teachers and parents in helping them. Data were collected…

  5. Wear-screening and joint simulation studies vs. materials selection and prosthesis design.

    PubMed

    Clarke, I C

    1982-01-01

    Satisfactory friction and wear performance of orthomedic biomaterials is an essential criterion for both hemiarthroplasty and total joint replacements. This report will chart the clinical historical experience of candidate biomaterials with their wear resistance and compare/contrast these data to experimental test predictions. The latter review will encompass publications dealing with both joint simulators and the more basic friction and wear screening devices. Special consideration will be given to the adequacy of the test protocol, the design of the experimental machines, and the accuracy of the measurement techniques. The discussion will then center on clinical reality vs. experimental adequacy and summarize current developments.

  6. Analytical and experimental investigation of liquid double drop dynamics: Preliminary design for space shuttle experiments

    NASA Technical Reports Server (NTRS)

    1981-01-01

    The preliminary grant assessed the use of laboratory experiments for simulating low g liquid drop experiments in the space shuttle environment. Investigations were begun of appropriate immiscible liquid systems, design of experimental apparatus and analyses. The current grant continued these topics, completed construction and preliminary testing of the experimental apparatus, and performed experiments on single and compound liquid drops. A continuing assessment of laboratory capabilities, and the interests of project personnel and available collaborators, led to, after consultations with NASA personnel, a research emphasis specializing on compound drops consisting of hollow plastic or elastic spheroids filled with liquids.

  7. 34 CFR 461.10 - What documents must a State submit to receive a grant?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the uses specified in section 322 of the Act are designed to expand or improve the quality of adult... concerning special experimental demonstration projects and teacher training projects supported under section...

  8. Integrated support structure

    NASA Technical Reports Server (NTRS)

    Bruneau, Stephen D.; Campbell, John T.; Struven, Christopher A.

    1990-01-01

    This Major Qualifying Project is part of the Advanced Space Design Program at WPI. The goal is to design a support structure for a NASA GetAway Special experimental canister. The payload integration, weight, volume, and structural integrity of the canister as specified by NASA guidelines were studied. The end result is a complete set of design drawings with interface drawings and data to specify the design and leave a base on which the next group can concentrate.

  9. Influence of detergents on water drift in cooling towers

    NASA Astrophysics Data System (ADS)

    Vitkovicova, Rut

    An influence of detergents on the water drift from the cooling tower was experimentally investigated. For this experimental measurements was used a model cooling tower, especially an experimental aerodynamic line, which is specially designed for the measurement and monitoring of processes taking place around the eliminators of the liquid phase. The effect of different concentrations of detergent in the cooling water on the drift of water droplets from a commonly used type eliminator was observed with visualization methods.

  10. Instructional Psychology 1976 - 1981,

    DTIC Science & Technology

    1982-06-01

    business it is to carry out applied work in the design of instructional content and delivery. These organizations include specialized divisions of...34learning disabilities" label: An experimental analysis. Comtemporary Educational Psychology, 1977, 2, 292-297. Allington, R. L. Sensitivity to

  11. Experimental Modeling of Sterilization Effects for Atmospheric Entry Heating on Microorganisms

    NASA Technical Reports Server (NTRS)

    Schubert, Wayne W.; Spry, James A.; Ronney, Paul D.; Pandian, Nathan R.; Welder, Eric

    2012-01-01

    The objective of this research was to design, build, and test an experimental apparatus for studying the parameters of atmospheric entry heating, and the inactivation of temperature-resistant bacterial spores. The apparatus is capable of controlled, rapid heating of sample coupons to temperatures of 200 to 350 C and above. The vacuum chamber permits operation under vacuum or special atmospheric gas mixtures.

  12. Outcomes of an Acceptance and Commitment Therapy-Based Skills Training Group for Students with High-Functioning Autism Spectrum Disorder: A Quasi-Experimental Pilot Study

    ERIC Educational Resources Information Center

    Pahnke, Johan; Lundgren, Tobias; Hursti, Timo; Hirvikoski, Tatja

    2014-01-01

    Autism spectrum disorder is characterized by social impairments and behavioural inflexibility. In this pilot study, the feasibility and outcomes of a 6-week acceptance and commitment therapy-based skills training group were evaluated in a special school setting using a quasi-experimental design (acceptance and commitment therapy/school classes as…

  13. Experimental research on air propellers

    NASA Technical Reports Server (NTRS)

    Durand, William F

    1918-01-01

    The purposes of the experimental investigation on the performance of air propellers described in this report are as follows: (1) the development of a series of design factors and coefficients drawn from model forms distributed with some regularity over the field of air-propeller design and intended to furnish a basis of check with similar work done in other aerodynamic laboratories, and as a point of departure for the further study of special or individual types and forms; (2) the establishment of a series of experimental values derived from models and intended for later use as a basis for comparison with similar results drawn from certain selected full-sized forms and tested in free flight.

  14. Design and experimental verification of a water-like pentamode material

    NASA Astrophysics Data System (ADS)

    Zhao, Aiguo; Zhao, Zhigao; Zhang, Xiangdong; Cai, Xuan; Wang, Lei; Wu, Tao; Chen, Hong

    2017-01-01

    Pentamode materials approximate tailorable artificial liquids. Recently, microscopic versions of these intricate structures have been fabricated, and the static mechanical experiments reveal that the ratio of bulk modulus to shear modulus as large as 1000 can be obtained. However, no direct acoustic experimental characterizations have been reported yet. In this paper, a water-like two-dimensional pentamode material sample is designed and fabricated with a single metallic material, which is a hollow metallic foam-like structure at centimeter scale. Acoustic simulation and experimental testing results indicate that the designed pentamode material mimics water in acoustic properties over a wide frequency range, i.e., it exhibits transparency when surrounded by water. This work contributes to the development of microstructural design of materials with specific modulus and density distribution, thus paving the way for the physical realization of special acoustic devices such as metamaterial lenses and vibration isolation.

  15. Behaviors of printed circuit boards due to microwave supported curing process of coating materials.

    PubMed

    Bremerkamp, Felix; Nowottnick, Mathias; Seehase, Dirk; Bui, Trinh Dung

    2012-01-01

    The Application of a microwave supported curing process for coatings in the field of electronic industry poses a challenge. Here the implementation of this technology is represented. Within the scope of the investigation special PCB Test Layouts were designed and the polymer curing process examined by the method of dielectric analysis. Furthermore the coupling of microwave radiation with conductive PCB structures was analyzed experimentally by means of special test boards. The formation of standing waves and regular heating distribution along the conductive wires on the PCB could be observed. The experimental results were compared with numerical simulation. In this context the numerical analysis of microwave PCB interaction led to important findings concerning wave propagation on wired PCB. The final valuation demonstrated a substantial similarity between numerical simulations and experimental results.

  16. Experimental CAD Course Uses Low-Cost Systems.

    ERIC Educational Resources Information Center

    Wohlers, Terry

    1984-01-01

    Describes the outstanding results obtained when a department of industrial sciences used special software on microcomputers to teach computer-aided design (CAD) as an alternative to much more expensive equipment. The systems used and prospects for the future are also considered. (JN)

  17. Model Selection in Systems Biology Depends on Experimental Design

    PubMed Central

    Silk, Daniel; Kirk, Paul D. W.; Barnes, Chris P.; Toni, Tina; Stumpf, Michael P. H.

    2014-01-01

    Experimental design attempts to maximise the information available for modelling tasks. An optimal experiment allows the inferred models or parameters to be chosen with the highest expected degree of confidence. If the true system is faithfully reproduced by one of the models, the merit of this approach is clear - we simply wish to identify it and the true parameters with the most certainty. However, in the more realistic situation where all models are incorrect or incomplete, the interpretation of model selection outcomes and the role of experimental design needs to be examined more carefully. Using a novel experimental design and model selection framework for stochastic state-space models, we perform high-throughput in-silico analyses on families of gene regulatory cascade models, to show that the selected model can depend on the experiment performed. We observe that experimental design thus makes confidence a criterion for model choice, but that this does not necessarily correlate with a model's predictive power or correctness. Finally, in the special case of linear ordinary differential equation (ODE) models, we explore how wrong a model has to be before it influences the conclusions of a model selection analysis. PMID:24922483

  18. Model selection in systems biology depends on experimental design.

    PubMed

    Silk, Daniel; Kirk, Paul D W; Barnes, Chris P; Toni, Tina; Stumpf, Michael P H

    2014-06-01

    Experimental design attempts to maximise the information available for modelling tasks. An optimal experiment allows the inferred models or parameters to be chosen with the highest expected degree of confidence. If the true system is faithfully reproduced by one of the models, the merit of this approach is clear - we simply wish to identify it and the true parameters with the most certainty. However, in the more realistic situation where all models are incorrect or incomplete, the interpretation of model selection outcomes and the role of experimental design needs to be examined more carefully. Using a novel experimental design and model selection framework for stochastic state-space models, we perform high-throughput in-silico analyses on families of gene regulatory cascade models, to show that the selected model can depend on the experiment performed. We observe that experimental design thus makes confidence a criterion for model choice, but that this does not necessarily correlate with a model's predictive power or correctness. Finally, in the special case of linear ordinary differential equation (ODE) models, we explore how wrong a model has to be before it influences the conclusions of a model selection analysis.

  19. 3D-glass molds for facile production of complex droplet microfluidic chips.

    PubMed

    Tovar, Miguel; Weber, Thomas; Hengoju, Sundar; Lovera, Andrea; Munser, Anne-Sophie; Shvydkiv, Oksana; Roth, Martin

    2018-03-01

    In order to leverage the immense potential of droplet microfluidics, it is necessary to simplify the process of chip design and fabrication. While polydimethylsiloxane (PDMS) replica molding has greatly revolutionized the chip-production process, its dependence on 2D-limited photolithography has restricted the design possibilities, as well as further dissemination of microfluidics to non-specialized labs. To break free from these restrictions while keeping fabrication straighforward, we introduce an approach to produce complex multi-height (3D) droplet microfluidic glass molds and subsequent chip production by PDMS replica molding. The glass molds are fabricated with sub-micrometric resolution using femtosecond laser machining technology, which allows directly realizing designs with multiple levels or even continuously changing heights. The presented technique significantly expands the experimental capabilities of the droplet microfluidic chip. It allows direct fabrication of multilevel structures such as droplet traps for prolonged observation and optical fiber integration for fluorescence detection. Furthermore, the fabrication of novel structures based on sloped channels (ramps) enables improved droplet reinjection and picoinjection or even a multi-parallelized drop generator based on gradients of confinement. The fabrication of these and other 3D-features is currently only available at such resolution by the presented strategy. Together with the simplicity of PDMS replica molding, this provides an accessible solution for both specialized and non-specialized labs to customize microfluidic experimentation and expand their possibilities.

  20. Army Field-Oriented S&T Experimentation Venues: A Comparative Analysis

    DTIC Science & Technology

    2011-09-01

    Microclimate Cooling Station (MCCS)). The Fort Benning AEWE provides the venue and the data collection and analysis. The costs to the S&T...forest, fields, etc.) and is designated as an Army experimental station with access to ground and an aerial fleet. Technology developers have optional...YTC), (2) tropical (the Tropic Regions Test Center, Panama Canal Zone), and (3) cold weather (CRTC, Bolio Lake Test Complex, AK. Special

  1. Broadband metamaterial lens antennas with special properties by controlling both refractive-index distribution and feed directivity

    NASA Astrophysics Data System (ADS)

    Ma, Qian; Shi, Chuan Bo; Chen, Tian Yi; Qing Qi, Mei; Li, Yun Bo; Cui, Tie Jun

    2018-04-01

    A new method is proposed to design gradient refractive-index metamaterial lens antennas by optimizing both the refractive-index distribution of the lens and the feed directivity. Comparing to the conventional design methods, source optimization provides a new degree of freedom to control aperture fields effectively. To demonstrate this method, two lenses with special properties based on this method are designed, to emit high-efficiency plane waves and fan-shaped beams, respectively. Both lenses have good performance and wide frequency band from 12 to 18 GHz, verifying the validity of the proposed method. The plane-wave emitting lens realized a high aperture efficiency of 75%, and the fan-beam lens achieved a high gain of 15 dB over board bandwidth. The experimental results have good agreement with the design targets and full-wave simulations.

  2. Experimental performance and acoustic investigation of modern, counterrotating blade concepts

    NASA Technical Reports Server (NTRS)

    Hoff, G. E.

    1990-01-01

    The aerodynamic, acoustic, and aeromechanical performance of counterrotating blade concepts were evaluated both theoretically and experimentally. Analytical methods development and design are addressed. Utilizing the analytical methods which evolved during the conduct of this work, aerodynamic and aeroacoustic predictions were developed, which were compared to NASA and GE wind tunnel test results. The detailed mechanical design and fabrication of five different composite shell/titanium spar counterrotating blade set configurations are presented. Design philosophy, analyses methods, and material geometry are addressed, as well as the influence of aerodynamics, aeromechanics, and aeroacoustics on the design procedures. Blade fabrication and quality control procedures are detailed; bench testing procedures and results of blade integrity verification are presented; and instrumentation associated with the bench testing also is identified. Additional hardware to support specialized testing is described, as are operating blade instrumentation and the associated stress limits. The five counterrotating blade concepts were scaled to a tip diameter of 2 feet, so they could be incorporated into MPS (model propulsion simulators). Aerodynamic and aeroacoustic performance testing was conducted in the NASA Lewis 8 x 6 supersonic and 9 x 15 V/STOL (vertical or short takeoff and landing) wind tunnels and in the GE freejet anechoic test chamber (Cell 41) to generate an experimental data base for these counterrotating blade designs. Test facility and MPS vehicle matrices are provided, and test procedures are presented. Effects on performance of rotor-to-rotor spacing, angle-of-attack, pylon proximity, blade number, reduced-diameter aft blades, and mismatched rotor speeds are addressed. Counterrotating blade and specialized aeromechanical hub stability test results are also furnished.

  3. The design, development and qualification of a lightweight antenna pointing mechanism

    NASA Technical Reports Server (NTRS)

    Shmulevitz, M.; Halsband, A.

    1996-01-01

    This paper describes the design, development, and qualification of a new lightweight and compact Antenna Pointing Mechanism (APM). The APM was specially designed to meet the stringent mass, envelope, and environmental requirements of OFFEQ experimental satellite. During the development phase, some problems were encountered with the brushless DC motors, slip ring contact resistance, and bearing drag torque. All of these problems were resolved, and two APM units have been operating successfully in orbit since April, 1995.

  4. A randomised controlled trial of empowerment training for Chinese abused pregnant women in Hong Kong.

    PubMed

    Tiwari, A; Leung, W C; Leung, T W; Humphreys, J; Parker, B; Ho, P C

    2005-09-01

    To evaluate the effectiveness of an empowerment intervention in reducing intimate partner violence (IPV) and improving health status. Randomised controlled trial. Antenatal clinic in a public hospital in Hong Kong. One hundred and ten Chinese pregnant women with a history of abuse by their intimate partners. Women were randomised to the experimental or control group. Experimental group women received empowerment training specially designed for Chinese abused pregnant women while the control group women received standard care for abused women. Data were collected at study entry and six weeks postnatal. IPV [on the Conflict Tactics Scale (CTS)], health-related quality of life (SF-36) and postnatal depression [Edinburgh Postnatal Depression Scale (EPDS)]. Following the training, the experimental group had significantly higher physical functioning and had significantly improved role limitation due to physical problems and emotional problems. They also reported less psychological (but not sexual) abuse, minor (but not severe) physical violence and had significantly lower postnatal depression scores. However, they reported more bodily pain. An empowerment intervention specially designed for Chinese abused pregnant women was effective in reducing IPV and improving the health status of the women.

  5. Design and adaptation of a novel supercritical extraction facility for operation in a glove box for recovery of radioactive elements

    NASA Astrophysics Data System (ADS)

    Kumar, V. Suresh; Kumar, R.; Sivaraman, N.; Ravisankar, G.; Vasudeva Rao, P. R.

    2010-09-01

    The design and development of a novel supercritical extraction experimental facility adapted for safe operation in a glove box for the recovery of radioactive elements from waste is described. The apparatus incorporates a high pressure extraction vessel, reciprocating pumps for delivering supercritical fluid and reagent, a back pressure regulator, and a collection chamber. All these components of the system have been specially designed for glove box adaptation and made modular to facilitate their replacement. Confinement of these materials must be ensured in a glove box to protect the operator and prevent contamination to the work area. Since handling of radioactive materials under high pressure (30 MPa) and temperature (up to 333 K) is involved in this process, the apparatus needs elaborate safety features in the design of the equipment, as well as modification of a standard glove box to accommodate the system. As a special safety feature to contain accidental leakage of carbon dioxide from the extraction vessel, a safety vessel has been specially designed and placed inside the glove box. The extraction vessel was enclosed in the safety vessel. The safety vessel was also incorporated with pressure sensing and controlling device.

  6. A novel field generator for magnetic stimulation in cell culture experiments.

    PubMed

    Vogt, G; Schrefl, A; Mitteregger, R; Falkenhagen, D

    1997-06-01

    A novel field generator specially designed to examine the influence of low frequency magnetic fields on specific cell material was constructed and characterized. The exposure unit described in this paper consists of a controller unit and three sets of coils. The field generator permits a precious definition of the revelant signal parameters and allows the superposition of alternating current (AC) and direct current (DC) magnetic fields. Critical system parameters were monitored continuously. The three sets of coils, each arranged in the Helmholtz Configuration were characterized. After data processing and visualization the results showed a constant and homogeneous field within the experimental area. The special coil design also allows their use in an incubator.

  7. Response to Intervention: Research and Practice

    ERIC Educational Resources Information Center

    Hall, Carol; Mahoney, Jamie

    2013-01-01

    Response to Intervention (RTI) is a service model designed to meet the learning needs of students prior to diagnosis and placement in special education settings. Results of a quantitative quasi-experimental research study to investigate the relationship between the RTI plan and self-reported implementation practices among general education…

  8. Acquisition Theory and Experimental Design: A Critique of Tomasello and Herron.

    ERIC Educational Resources Information Center

    Beck, Maria-Luise; Eubank, Lynn

    1991-01-01

    Caution should be taken in viewing previous research indicating that negative evidence, a special type of error correction to eliminate overgeneralizations, could be crucial to second-language learning, because the underlying theories adopted for that research possibly could be flawed. (10 references) (CB)

  9. Statistical process control in nursing research.

    PubMed

    Polit, Denise F; Chaboyer, Wendy

    2012-02-01

    In intervention studies in which randomization to groups is not possible, researchers typically use quasi-experimental designs. Time series designs are strong quasi-experimental designs but are seldom used, perhaps because of technical and analytic hurdles. Statistical process control (SPC) is an alternative analytic approach to testing hypotheses about intervention effects using data collected over time. SPC, like traditional statistical methods, is a tool for understanding variation and involves the construction of control charts that distinguish between normal, random fluctuations (common cause variation), and statistically significant special cause variation that can result from an innovation. The purpose of this article is to provide an overview of SPC and to illustrate its use in a study of a nursing practice improvement intervention. Copyright © 2011 Wiley Periodicals, Inc.

  10. Proceedingsof the International Conference on Inverse Design Concepts and Optimization in Engineering Sciences (3rd) ICIDES-III Held in Washington, DC 23-25 October 1991

    DTIC Science & Technology

    1991-09-01

    jet engine (even rocket engine ) rotating components. Examples have been presented for compressor and turbine profile designs. Both methods are...used for experimental studies on plasmatrons and gasdynamic stands in which the gas jets are created by special aviation and rocket engines . Similar... Aviation Institute, Bd. Pacli 220, 77538 Bucharest, ROMANIA 45 --’, Inverse Airfoil Design Procedure .Uging a Mliitigrid Navier-Stokes ,Method) J.B

  11. Experimental verification and practical application of torquewhirl theory of rotordynamic instability

    NASA Technical Reports Server (NTRS)

    Vance, J. M.; Noah, S. T.; Yim, K. B.

    1985-01-01

    A theory developed by Vance in 1978 to explain the destabilizing effect of torque on a whirling rotor was experimentally verified. The measurements made on a specially designed test apparatus are described. New computer models were also developed to investigate the effect of torque on rotordynamic stability of multidisk flexible rotor bearing systems. The effect of torque was found to be most pronounced when the system is already marginally stable from other influences. The modifications required to include torque in a typical shaft transfer matrix are described, and results are shown which identify the type of rotor design most sensitive to load torque.

  12. Integrating Reform-Oriented Math Instruction in Special Education Settings

    ERIC Educational Resources Information Center

    Bottge, Brian A.; Rueda, Enrique; LaRoque, Perry T.; Serlin, Ronald C.; Kwon, Jungmin

    2007-01-01

    This mixed-methods study assessed the effects of Enhanced Anchored Instruction (EAI) on the math performance of adolescents with learning disabilities in math (MLD). A quasi-experimental pretest-posttest control group design with switching replications was used to measure students' computation and problem-solving skills on EAI compared to control…

  13. Conceptual Questions and Lack of Formal Reasoning: Are They Mutually Exclusive?

    ERIC Educational Resources Information Center

    Igaz, Csaba; Proksa, Miroslav

    2012-01-01

    Using specially designed conceptual question pairs, 9th grade students were tested on tasks (presented as experimental situations in pictorial form) that involved controlling the variables' scheme of formal reasoning. The question topics focused on these three chemical contexts: chemistry in everyday life, chemistry without formal concepts, and…

  14. Schizophrenia and Crisis Theory.

    ERIC Educational Resources Information Center

    Mosher, Loren R.; And Others

    An experimental two-year treatment project designed to help the acute schizophrenic emerge from psychosis a stronger, better integrated person is underway at Soteria House, a comfortable 16-room house in the San Francisco Bay area. The project will compare the effects of treatment in this special facility with those of "usual" treatment in a…

  15. Rotating Fluidized Bed Reactor for Space Nuclear Propulsion. Annual Report; Design Studies and Experimental Results

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The rotating fluidized bed reactor concept is being investigated for possible application in nuclear propulsion systems. Physics calculations show U-233 to be superior to U-235 as a fuel for a cavity reactor of this type. Preliminary estimates of the effect of hydrogen in the reactor, reflector material, and power peaking are given. A preliminary engineering analysis was made for U-235 and U-233 fueled systems. An evaluation of the parameters affecting the design of the system is given, along with the thrust-to-weight ratios. The experimental equipment is described, as are the special photographic techniques and procedures. Characteristics of the fluidized bed and experimental results are given, including photographic evidence of bed fluidization at high rotational velocities.

  16. Applied Integrated Design in Composite UAV Development

    NASA Astrophysics Data System (ADS)

    Vasić, Zoran; Maksimović, Stevan; Georgijević, Dragutin

    2018-04-01

    This paper presents a modern approach to integrated development of Unmanned Aerial Vehicle made of laminated composite materials from conceptual design, through detail design, strength and stiffness analyses, definition and management of design and production data, detailed tests results and other activities related to development of laminated composite structures with main of its particularities in comparison to metal structures. Special attention in this work is focused to management processes of product data during life cycle of an UAV and experimental tests of its composite wing. Experience shows that the automation management processes of product data during life cycle, as well as processes of manufacturing, are inevitable if a company wants to get cheaper and quality composite aircraft structures. One of the most effective ways of successful management of product data today is Product Life cycle Management (PLM). In terms of the PLM, a spectrum of special measures and provisions has to be implemented when defining fiber-reinforced composite material structures in comparison to designing with metals which is elaborated in the paper.

  17. The development, design and test of a 66 W/kg (30-W/lb) roll-up solar array

    NASA Technical Reports Server (NTRS)

    Hasbach, W. A.; Ross, R. G., Jr.

    1972-01-01

    A program to develop a 250 square foot roll-up solar array with a power-to-weight ratio exceeding 30 watts per pound is described. The system design and fabrication of a full scale engineering development model are discussed. The system and development test program results are presented. Special test equipment and test procedures are included, together with comparisons of experimental and analytical results.

  18. "Technical note. Harmonization of the multi-scale multi-model activities HTAP, AQMEII and MICS-Asia: simulations, emission inventories, boundary conditions and output formats." For submission to ACP Special Issue on "Global and regional assessment of intercontinental transport of air pollution: results from HTAP, AQMEII and MICS"

    EPA Science Inventory

    The ACP Special Issue is being organized to draw together analysis of a set of cooperative modeling experiments (referred to as HTAP2). The purpose of this technical note is to provide a common description of the experimental design and set up for HTAP2 that can be referred to b...

  19. 75 FR 36467 - Livability Initiative Under Special Experimental Project No. 14

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ...] Livability Initiative Under Special Experimental Project No. 14 AGENCY: Federal Highway Administration (FHWA...). Under this initiative, the FHWA will utilize Special Experimental Project No. 14 (SEP-14) to permit, on... in order to use Federal-aid highway funds. DATES: This new experimental project is being initiated on...

  20. Imaginative Use of Nonbroadcast Technology Directs Social Services to Isolated Audiences.

    ERIC Educational Resources Information Center

    Erdman, Ann

    1981-01-01

    The keynote article in this issue summarizes some of the lessons learned after a decade of using satellites for public service, and after five years of experimentation with information technologies designed for specialized audiences. Community service programs in the Appalachian Mountain and Rocky Mountain regions and in the state of Alaska are…

  1. 26 CFR 1.513-1 - Definition of unrelated trade or business.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 7 2014-04-01 2013-04-01 true Definition of unrelated trade or business. 1.513... experimental dairy herd maintained for scientific purposes by a research organization described in section 501... 501(c)(3) has a theater auditorium which is specially designed and equipped for showing of educational...

  2. 26 CFR 1.513-1 - Definition of unrelated trade or business.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 7 2011-04-01 2009-04-01 true Definition of unrelated trade or business. 1.513... experimental dairy herd maintained for scientific purposes by a research organization described in section 501... 501(c)(3) has a theater auditorium which is specially designed and equipped for showing of educational...

  3. 26 CFR 1.513-1 - Definition of unrelated trade or business.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Definition of unrelated trade or business. 1.513... experimental dairy herd maintained for scientific purposes by a research organization described in section 501... 501(c)(3) has a theater auditorium which is specially designed and equipped for showing of educational...

  4. Development and Use of Curricular Adaptations for Students Receiving Special Education Services

    ERIC Educational Resources Information Center

    Kurth, Jennifer A.; Keegan, Lissa

    2014-01-01

    This study is a quasi-experimental descriptive design, with existing educator-made adaptations evaluated. The goals of this study were to (a) describe how educators develop adaptations and (b) evaluate the effectiveness of educator-made adaptations in facilitating the learning of students with disabilities. Findings suggest that (a) most…

  5. Integrating Theatre Arts Techniques into Your Curriculum

    ERIC Educational Resources Information Center

    McFadden, Lauren Bosworth

    2012-01-01

    The purpose of this study was to examine how the infusion of theatre arts into the language arts and social studies curricula in grades 4 and 5 impacted the cognitive and prosocial development of special populations, as well as the students' attitudes toward learning. An experimental/control group design was employed. Various instruments were used…

  6. 2011 Special Operations Forces Industry Conference

    DTIC Science & Technology

    2011-05-19

    to USSOCOM acquisition objectives and challenges . The Forum is designed to be an informative discussion, with audience participation, between... Challenge UNCLASSIFIED UNCLAS IF ED UNCLASSIFIED UNCLASSIFIED Acquisition Enterprise DOD and Service Labs, International Partners, Industry IR&D SOF...Experimentation • Mission – Support Concept & Solution Development for SOF Capability Gaps, Technology Thrust Areas & Warfighter Challenges • Objectives

  7. An Arduino-Based Experiment Designed to Clarify the Transition to Total Internal Reflection

    ERIC Educational Resources Information Center

    Atkin, Keith

    2018-01-01

    The topic of refraction and reflection of light at the boundary of transparent media is a fundamentally important one. The special case of total internal reflection is however commonly misrepresented in elementary textbooks. This paper addresses the problem and describes an experimental procedure for measuring and displaying reflected and…

  8. Exploring the Use of iPads for Literacy Instruction in the 1:1 K-6 Classroom

    ERIC Educational Resources Information Center

    Mallernee, Nora

    2017-01-01

    This non-experimental correlational quantitative study was designed to explore the effects of specialized professional development, age, gender, and years of teaching experience on the successful integration of iPads into classroom literacy education among K-6 students. The study uses the teachers' Technological Pedagogical Content Knowledge…

  9. Phenomena induced by charged particle beams. [experimental design for Spacelab

    NASA Technical Reports Server (NTRS)

    Beghin, C.

    1981-01-01

    The injection of energetic particles along the Earth's magnetic field lines is a possible remote sensing method for measuring the electric fields parallel to the magnetic field with good time resolution over the entire magnetic field. Neutralization processes, return-current effects, dynamics of the beams, triggered instabilities, and waves must be investigated before the fundamental question about proper experimental conditions, such as energy, intensity and divergence of the beams, pitch-angle injection, ion species, proper probes and detectors and their location, and rendezvous conditions, can be resolved. An experiment designed to provide a better understanding of these special physical processes and to provide some answers to questions concerning beam injection techniques is described.

  10. Design of Circular, Square, Single, and Multi-layer Induction Coils for Electromagnetic Priming Using Inductance Estimates

    NASA Astrophysics Data System (ADS)

    Fritzsch, Robert; Kennedy, Mark W.; Aune, Ragnhild E.

    2018-02-01

    Special induction coils used for electro magnetic priming of ceramic foam filters in liquid metal filtration have been designed using a combination of analytical and finite element modeling. Relatively simple empirical equations published by Wheeler in 1928 and 1982 have been used during the design process. The equations were found to accurately predict the z-component of the magnetic flux densities of both single- and multi-layer coils as verified both experimentally and by using COMSOL® 5.1 multiphysics simulations.

  11. What is the best reference RNA? And other questions regarding the design and analysis of two-color microarray experiments.

    PubMed

    Kerr, Kathleen F; Serikawa, Kyle A; Wei, Caimiao; Peters, Mette A; Bumgarner, Roger E

    2007-01-01

    The reference design is a practical and popular choice for microarray studies using two-color platforms. In the reference design, the reference RNA uses half of all array resources, leading investigators to ask: What is the best reference RNA? We propose a novel method for evaluating reference RNAs and present the results of an experiment that was specially designed to evaluate three common choices of reference RNA. We found no compelling evidence in favor of any particular reference. In particular, a commercial reference showed no advantage in our data. Our experimental design also enabled a new way to test the effectiveness of pre-processing methods for two-color arrays. Our results favor using intensity normalization and foregoing background subtraction. Finally, we evaluate the sensitivity and specificity of data quality filters, and we propose a new filter that can be applied to any experimental design and does not rely on replicate hybridizations.

  12. Theoretical studies on the mechanical behavior of granular materials under very low intergranular stresses

    NASA Technical Reports Server (NTRS)

    French, Kenneth W., Jr.

    1986-01-01

    The salient aspects of the theoretical modeling of a conventional triaxial test (CTC) of a cohesionless granular medium with stress and strain rate loading are described. Included are a controllable gravitational body force and provision for low confining pressure and/or very low intergranular stress. The modeling includes rational, analytic, and numerical phases, all in various stages of development. The numerical evolutions of theoretical models will be used in final design stages and in the analysis of the experimental data. In this the experimental design stage, it is of special interest to include in the candidate considerations every anomaly found in preliminary terrestrial experimentation. Most of the anomalies will be eliminated by design or enhanced for measurement as the project progresses. The main aspect of design being not the physical apparatus but the type and trajectories of loading elected. The major considerations that have been treated are: appearance and growth of local surface aberrations, stress-power coefficients, strain types, optical strain, radial bead migration, and measures of rotation for the proper stress flux.

  13. Broadband acoustic phased array with subwavelength active tube array

    NASA Astrophysics Data System (ADS)

    Li, Xiao-Yan; Yang, Zhang-Zhao; Zhu, Yi-Fan; Zou, Xin-Ye; Cheng, Jian-Chun

    2018-02-01

    Acoustic metasurfaces provide a way to manipulate wavefronts at anomalous reflection or refraction angles through subwavelength structures. Here, based on the generalized Snell's refraction law for acoustic metasurfaces and the classical acoustic phased array (PA) theory, a broadband acoustic PA with a subwavelength active tube array has been proposed to form a special acoustic beam and to determine the directivity characteristics of the acoustic source. Theoretical analysis shows that the dispersionless wavefront manipulation can be realized by the gradient model of the active tube array, and a wide working frequency band can be obtained in practical applications from the simulated and experimental results. The numerical results of forming a special acoustic beam and establishing an acoustic focus model with an arbitrary focal position are consistent with the theoretical predictions. The experimental results agree well with the simulated results in the model of forming the acoustic beam of 45 ° . By combining acoustic metamaterials and conventional acoustic PA, the model of the active tube array paves a way to design a composite acoustic PA with high radiation efficiency and system robustness without the need for any complex circuit control system. This design concept is expected to be used in the design of ultrasonic therapy devices and high-efficiency transducers.

  14. Cruella: developing a scalable tissue microarray data management system.

    PubMed

    Cowan, James D; Rimm, David L; Tuck, David P

    2006-06-01

    Compared with DNA microarray technology, relatively little information is available concerning the special requirements, design influences, and implementation strategies of data systems for tissue microarray technology. These issues include the requirement to accommodate new and different data elements for each new project as well as the need to interact with pre-existing models for clinical, biological, and specimen-related data. To design and implement a flexible, scalable tissue microarray data storage and management system that could accommodate information regarding different disease types and different clinical investigators, and different clinical investigation questions, all of which could potentially contribute unforeseen data types that require dynamic integration with existing data. The unpredictability of the data elements combined with the novelty of automated analysis algorithms and controlled vocabulary standards in this area require flexible designs and practical decisions. Our design includes a custom Java-based persistence layer to mediate and facilitate interaction with an object-relational database model and a novel database schema. User interaction is provided through a Java Servlet-based Web interface. Cruella has become an indispensable resource and is used by dozens of researchers every day. The system stores millions of experimental values covering more than 300 biological markers and more than 30 disease types. The experimental data are merged with clinical data that has been aggregated from multiple sources and is available to the researchers for management, analysis, and export. Cruella addresses many of the special considerations for managing tissue microarray experimental data and the associated clinical information. A metadata-driven approach provides a practical solution to many of the unique issues inherent in tissue microarray research, and allows relatively straightforward interoperability with and accommodation of new data models.

  15. 75 FR 15767 - Livability Initiative under Special Experimental Project No. 14

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-30

    ...] Livability Initiative under Special Experimental Project No. 14 AGENCY: Federal Highway Administration (FHWA... initiative to harmonize and coordinate the Federal-aid Highway Program with grant-in- aid programs... (EPA). Under this initiative, the FHWA intends to utilize Special Experimental Project No. 14 (SEP-14...

  16. A Cognitive Strategy Instruction to Improve Math Calculation for Children with ADHD and LD: A Randomized Controlled Study

    ERIC Educational Resources Information Center

    Iseman, Jackie S.; Naglieri, Jack A.

    2011-01-01

    The authors examined the effectiveness of cognitive strategy instruction based on PASS (Planning, Attention, Simultaneous, Successive) given by special education teachers to students with ADHD randomly assigned by classroom. Students in the experimental group were exposed to a brief cognitive strategy instruction for 10 days, which was designed to…

  17. Are Student Veterans a Traditional, Nontraditional, or Special Population? A Study of Veterans on the Auburn University Campus

    ERIC Educational Resources Information Center

    Pattillo, Stephen Prescott

    2011-01-01

    This non-experimental study used, with the Educational Testing Service's permission, an updated 1946 Student Opinion Questionnaire (originally designed to compare WWII veterans and nonveterans) to collect data regarding student backgrounds, attitudes and motives, worries and concerns, use of time, and perceptions of respect concerning nonveterans,…

  18. Multimedia Scenario Based Learning Programme for Enhancing the English Language Efficiency among Primary School Students

    ERIC Educational Resources Information Center

    Tupe, Navnath

    2015-01-01

    This research was undertaken with a view to assess the deficiencies in English language among Primary School Children and to develop Multimedia Scenario Based Learning Programme (MSBLP) for mastery of English language which required special attention and effective treatment. The experimental study with pre-test, post-test control group design was…

  19. Demonstration of decomposition and optimization in the design of experimental space systems

    NASA Technical Reports Server (NTRS)

    Padula, Sharon; Sandridge, Chris A.; Haftka, Raphael T.; Walsh, Joanne L.

    1989-01-01

    Effective design strategies for a class of systems which may be termed Experimental Space Systems (ESS) are needed. These systems, which include large space antenna and observatories, space platforms, earth satellites and deep space explorers, have special characteristics which make them particularly difficult to design. It is argued here that these same characteristics encourage the use of advanced computer-aided optimization and planning techniques. The broad goal of this research is to develop optimization strategies for the design of ESS. These strategics would account for the possibly conflicting requirements of mission life, safety, scientific payoffs, initial system cost, launch limitations and maintenance costs. The strategies must also preserve the coupling between disciplines or between subsystems. Here, the specific purpose is to describe a computer-aided planning and scheduling technique. This technique provides the designer with a way to map the flow of data between multidisciplinary analyses. The technique is important because it enables the designer to decompose the system design problem into a number of smaller subproblems. The planning and scheduling technique is demonstrated by its application to a specific preliminary design problem.

  20. The Problem of Size in Robust Design

    NASA Technical Reports Server (NTRS)

    Koch, Patrick N.; Allen, Janet K.; Mistree, Farrokh; Mavris, Dimitri

    1997-01-01

    To facilitate the effective solution of multidisciplinary, multiobjective complex design problems, a departure from the traditional parametric design analysis and single objective optimization approaches is necessary in the preliminary stages of design. A necessary tradeoff becomes one of efficiency vs. accuracy as approximate models are sought to allow fast analysis and effective exploration of a preliminary design space. In this paper we apply a general robust design approach for efficient and comprehensive preliminary design to a large complex system: a high speed civil transport (HSCT) aircraft. Specifically, we investigate the HSCT wing configuration design, incorporating life cycle economic uncertainties to identify economically robust solutions. The approach is built on the foundation of statistical experimentation and modeling techniques and robust design principles, and is specialized through incorporation of the compromise Decision Support Problem for multiobjective design. For large problems however, as in the HSCT example, this robust design approach developed for efficient and comprehensive design breaks down with the problem of size - combinatorial explosion in experimentation and model building with number of variables -and both efficiency and accuracy are sacrificed. Our focus in this paper is on identifying and discussing the implications and open issues associated with the problem of size for the preliminary design of large complex systems.

  1. Initial characterization of an Experimental Referee Broadened-Specification (ERBS) aviation turbine fuel

    NASA Technical Reports Server (NTRS)

    Prok, G. M.; Seng, G. T.

    1980-01-01

    Characterization data and a hydrocarbon compositional analysis are presented for a research test fuel designated as an experimental referee broadened-specification aviation turbine fuel. This research fuel, which is a special blend of kerosene and hydrotreated catalytic gas oil, is a hypothetical representation of a future fuel should it become necessary to broaden current kerojet specifications. It is used as a reference fuel in research investigations into the effects of fuel property variations on the performance and durability of jet aircraft components, including combustors and fuel systems.

  2. Application of a Computer Model to Various Specifications of Fuel Injection System for DI Diesel Engines

    NASA Astrophysics Data System (ADS)

    Yamanishi, Manabu

    A combined experimental and computational investigation was performed in order to evaluate the effects of various design parameters of an in-line injection pump on the nozzle exit characteristics for DI diesel engines. Measurements of the pump chamber pressure and the delivery valve lift were included for validation by using specially designed transducers installed inside the pump. The results confirm that the simulation model is capable of predicting the pump operation for all the different designs investigated pump operating conditions. Following the successful validation of this model, parametric studies were performed which allow for improved fuel injection system design.

  3. Long Term Follow-Through of Participants in the Vermont Experimental and Demonstration Project.

    ERIC Educational Resources Information Center

    Cashman, John R.; Mattson, Robert E.

    The report describes a Vermont project begun in 1970 and designed to assess the long term value of the Special Work Project (SWP), or Public Service Employment, as a vehicle for providing transitional employment to unemployed members of low income families with children receiving public aid. The study attempted to contact and interview the 609…

  4. Demonstration of differential phase-shift keying demodulation at 10 Gbit/s optimal fiber Bragg grating filters.

    PubMed

    Gatti, Davide; Galzerano, Gianluca; Laporta, Paolo; Longhi, Stefano; Janner, Davide; Guglierame, Andrea; Belmonte, Michele

    2008-07-01

    Optimal demodulation of differential phase-shift keying signals at 10 Gbit/s is experimentally demonstrated using a specially designed structured fiber Bragg grating composed by Fabry-Perot coupled cavities. Bit-error-rate measurements show that, as compared with a conventional Gaussian-shaped filter, our demodulator gives approximately 2.8 dB performance improvement.

  5. Bed inventory overturn in a circulating fluid bed riser with pant-leg structure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jinjing Li; Wei Wang; Hairui Yang

    2009-05-15

    The special phenomenon, nominated as bed inventory overturn, in circulating fluid bed (CFB) riser with pant-leg structure was studied with model calculation and experimental work. A compounded pressure drop mathematic model was developed and validated with the experimental data in a cold experimental test rig. The model calculation results agree well with the measured data. In addition, the intensity of bed inventory overturn is directly proportional to the fluidizing velocity and is inversely proportional to the branch point height. The results in the present study provide significant information for the design and operation of a CFB boiler with pant-leg structure.more » 15 refs., 10 figs., 1 tab.« less

  6. designGG: an R-package and web tool for the optimal design of genetical genomics experiments.

    PubMed

    Li, Yang; Swertz, Morris A; Vera, Gonzalo; Fu, Jingyuan; Breitling, Rainer; Jansen, Ritsert C

    2009-06-18

    High-dimensional biomolecular profiling of genetically different individuals in one or more environmental conditions is an increasingly popular strategy for exploring the functioning of complex biological systems. The optimal design of such genetical genomics experiments in a cost-efficient and effective way is not trivial. This paper presents designGG, an R package for designing optimal genetical genomics experiments. A web implementation for designGG is available at http://gbic.biol.rug.nl/designGG. All software, including source code and documentation, is freely available. DesignGG allows users to intelligently select and allocate individuals to experimental units and conditions such as drug treatment. The user can maximize the power and resolution of detecting genetic, environmental and interaction effects in a genome-wide or local mode by giving more weight to genome regions of special interest, such as previously detected phenotypic quantitative trait loci. This will help to achieve high power and more accurate estimates of the effects of interesting factors, and thus yield a more reliable biological interpretation of data. DesignGG is applicable to linkage analysis of experimental crosses, e.g. recombinant inbred lines, as well as to association analysis of natural populations.

  7. Experimental investigation of combustor effects on rocket thrust chamber performance

    NASA Technical Reports Server (NTRS)

    1972-01-01

    A design and experimental program to develop special instrumentation systems, design engine hardware, and conduct tests using LOX/GH2 propellants in which the propellant flow stratification was controlled is described. The mixture ratio was varied from 4.6 to 6 overall. The mixture ratios in the core and outer zone were varied from 3.5 to 6 and 5 to 8, respectively. The range in boundary layer coolant was from 0 to 10 percent of the fuel. The nominal chamber pressure and thrust were 225 psia and 7000 pounds, respectively. Pressure and heat flux profiles as well as gas sampling of the exhaust products were obtained. Specific impulse efficiencies of approximately 94 percent and characteristic velocity efficiencies of approximately 97 percent were obtained during the experiments.

  8. Experimental Design for Stochastic Models of Nonlinear Signaling Pathways Using an Interval-Wise Linear Noise Approximation and State Estimation.

    PubMed

    Zimmer, Christoph

    2016-01-01

    Computational modeling is a key technique for analyzing models in systems biology. There are well established methods for the estimation of the kinetic parameters in models of ordinary differential equations (ODE). Experimental design techniques aim at devising experiments that maximize the information encoded in the data. For ODE models there are well established approaches for experimental design and even software tools. However, data from single cell experiments on signaling pathways in systems biology often shows intrinsic stochastic effects prompting the development of specialized methods. While simulation methods have been developed for decades and parameter estimation has been targeted for the last years, only very few articles focus on experimental design for stochastic models. The Fisher information matrix is the central measure for experimental design as it evaluates the information an experiment provides for parameter estimation. This article suggest an approach to calculate a Fisher information matrix for models containing intrinsic stochasticity and high nonlinearity. The approach makes use of a recently suggested multiple shooting for stochastic systems (MSS) objective function. The Fisher information matrix is calculated by evaluating pseudo data with the MSS technique. The performance of the approach is evaluated with simulation studies on an Immigration-Death, a Lotka-Volterra, and a Calcium oscillation model. The Calcium oscillation model is a particularly appropriate case study as it contains the challenges inherent to signaling pathways: high nonlinearity, intrinsic stochasticity, a qualitatively different behavior from an ODE solution, and partial observability. The computational speed of the MSS approach for the Fisher information matrix allows for an application in realistic size models.

  9. Computational Design of Functionalized Metal–Organic Framework Nodes for Catalysis

    PubMed Central

    2017-01-01

    Recent progress in the synthesis and characterization of metal–organic frameworks (MOFs) has opened the door to an increasing number of possible catalytic applications. The great versatility of MOFs creates a large chemical space, whose thorough experimental examination becomes practically impossible. Therefore, computational modeling is a key tool to support, rationalize, and guide experimental efforts. In this outlook we survey the main methodologies employed to model MOFs for catalysis, and we review selected recent studies on the functionalization of their nodes. We pay special attention to catalytic applications involving natural gas conversion. PMID:29392172

  10. Prediction of light aircraft interior sound pressure level from the measured sound power flowing in to the cabin

    NASA Technical Reports Server (NTRS)

    Atwal, Mahabir S.; Heitman, Karen E.; Crocker, Malcolm J.

    1986-01-01

    The validity of the room equation of Crocker and Price (1982) for predicting the cabin interior sound pressure level was experimentally tested using a specially constructed setup for simultaneous measurements of transmitted sound intensity and interior sound pressure levels. Using measured values of the reverberation time and transmitted intensities, the equation was used to predict the space-averaged interior sound pressure level for three different fuselage conditions. The general agreement between the room equation and experimental test data is considered good enough for this equation to be used for preliminary design studies.

  11. ITER Magnet Feeder: Design, Manufacturing and Integration

    NASA Astrophysics Data System (ADS)

    CHEN, Yonghua; ILIN, Y.; M., SU; C., NICHOLAS; BAUER, P.; JAROMIR, F.; LU, Kun; CHENG, Yong; SONG, Yuntao; LIU, Chen; HUANG, Xiongyi; ZHOU, Tingzhi; SHEN, Guang; WANG, Zhongwei; FENG, Hansheng; SHEN, Junsong

    2015-03-01

    The International Thermonuclear Experimental Reactor (ITER) feeder procurement is now well underway. The feeder design has been improved by the feeder teams at the ITER Organization (IO) and the Institute of Plasma Physics, Chinese Academy of Sciences (ASIPP) in the last 2 years along with analyses and qualification activities. The feeder design is being progressively finalized. In addition, the preparation of qualification and manufacturing are well scheduled at ASIPP. This paper mainly presents the design, the overview of manufacturing and the status of integration on the ITER magnet feeders. supported by the National Special Support for R&D on Science and Technology for ITER (Ministry of Public Security of the People's Republic of China-MPS) (No. 2008GB102000)

  12. An Arduino-based experiment designed to clarify the transition to total internal reflection

    NASA Astrophysics Data System (ADS)

    Atkin, Keith

    2018-03-01

    The topic of refraction and reflection of light at the boundary of transparent media is a fundamentally important one. The special case of total internal reflection is however commonly misrepresented in elementary textbooks. This paper addresses the problem and describes an experimental procedure for measuring and displaying reflected and transmitted light intensities using readily available components and the Arduino microcontroller.

  13. An all digital phase locked loop for FM demodulation.

    NASA Technical Reports Server (NTRS)

    Greco, J.; Garodnick, J.; Schilling, D. L.

    1972-01-01

    A phase-locked loop designed with all-digital circuitry which avoids certain problems, and a digital voltage controlled oscillator algorithm are described. The system operates synchronously and performs all required digital calculations within one sampling period, thereby performing as a real-time special-purpose computer. The SNR ratio is computed for frequency offsets and sinusoidal modulation, and experimental results verify the theoretical calculations.

  14. Evaluation of a Group Intervention to Assist Aging Parents with Permanency Planning for an Adult Offspring with Special Needs

    ERIC Educational Resources Information Center

    Botsford, Anne L.; Rule, David

    2004-01-01

    More than three-fourths of older adults with developmental disabilities and mental illness live in the community with aging parents, the majority of whom do not complete plans for the residential, financial, and legal future of their offspring. The authors used a true experimental design to evaluate the effectiveness of a six-week…

  15. The 1986 Get Away Special Experimenter's Symposium

    NASA Technical Reports Server (NTRS)

    Thomas, Lawrence R. (Editor); Mosier, Frances L. (Editor)

    1987-01-01

    The 1986 Get Away Special (GAS) Experimenter's Symposium will provide a formal opportunity for GAS Experimenter's to share the results of their projects. The focus of this symposium is on payloads that will be flown in the future.

  16. Surface topography acquisition method for double-sided near-right-angle structured surfaces based on dual-probe wavelength scanning interferometry.

    PubMed

    Zhang, Tao; Gao, Feng; Jiang, Xiangqian

    2017-10-02

    This paper proposes an approach to measure double-sided near-right-angle structured surfaces based on dual-probe wavelength scanning interferometry (DPWSI). The principle and mathematical model is discussed and the measurement system is calibrated with a combination of standard step-height samples for both probes vertical calibrations and a specially designed calibration artefact for building up the space coordinate relationship of the dual-probe measurement system. The topography of the specially designed artefact is acquired by combining the measurement results with white light scanning interferometer (WLSI) and scanning electron microscope (SEM) for reference. The relative location of the two probes is then determined with 3D registration algorithm. Experimental validation of the approach is provided and the results show that the method is able to measure double-sided near-right-angle structured surfaces with nanometer vertical resolution and micrometer lateral resolution.

  17. Review of sonic fatigue technology

    NASA Technical Reports Server (NTRS)

    Clarkson, B. L.

    1994-01-01

    From the early-1960s until the mid-1980s, there was very little theoretical development for sonic fatigue prediction. Design nomographs based on simple theoretical models and results of specially designed tests were developed for most common aircraft structures. The use of advanced composites in the 1980s, however, generated an increased interest in development of more sophisticated theoretical models because of the possibilities for a much wider range of structural designs. The purpose of this report is to review sonic fatigue technology and, in particular, to assess recent developments. It also suggests a plan for a coordinated program of theoretical and experimental work to meet the anticipated needs of future aerospace vehicles.

  18. Design of Rail Instrumentation for Wind Tunnel Sonic Boom Measurements and Computational-Experimental Comparisons

    NASA Technical Reports Server (NTRS)

    Cliff, Susan E.; Elmiligui, A.; Aftosmis, M.; Morgenstern, J.; Durston, D.; Thomas, S.

    2012-01-01

    An innovative pressure rail concept for wind tunnel sonic boom testing of modern aircraft configurations with very low overpressures was designed with an adjoint-based solution-adapted Cartesian grid method. The computational method requires accurate free-air calculations of a test article as well as solutions modeling the influence of rail and tunnel walls. Specialized grids for accurate Euler and Navier-Stokes sonic boom computations were used on several test articles including complete aircraft models with flow-through nacelles. The computed pressure signatures are compared with recent results from the NASA 9- x 7-foot Supersonic Wind Tunnel using the advanced rail design.

  19. The centrifuge facility - A life sciences research laboratory for Space Station Freedom

    NASA Technical Reports Server (NTRS)

    Fuller, Charles A.; Johnson, Catherine C.; Hargens, Alan R.

    1991-01-01

    The paper describes the centrifugal facility that is presently being developed by NASA for studies aboard the Space Station Freedom on the role of gravity, or its absence, at varying intensities for varying periods of time and with multiple model systems. Special attention is given to the design of the centrifuge system, the habitats designed to hold plants and animals, the glovebox system designed for experimental manipulations of the specimens, and the service unit. Studies planned for the facility will include experiments in the following disciplines: cell and developmental biology, plant biology, regulatory physiology, musculoskeletal physiology, behavior and performance, neurosciences, cardiopulmonary physiology, and environmental health and radiation.

  20. [Effects of special mouth care with an aroma solution on oral status and oral cavity microorganism growth in elderly stroke patients].

    PubMed

    Lee, Eun-Hye; Park, Hyojung

    2015-02-01

    This study was conducted to examine the effect of oral care with an aroma solution on oral status and oral cavity microorganism growth in elderly patients with stroke. A non-equivalent control group, with a pretest-posttest design was used in this study. The participants were assigned to the experimental group (n=30) that received oral care with an aroma solution or the control group (n=31) that received 0.9% saline solution. To identify the effect of the experimental treatments, objective/subjective assessments of oral status and oral cavity microorganism growth were performed using the oral assessment guide, oral perception guide, and oral swab culture. Data were analyzed using Chi-square test, Fisher's exact test, and t-test with the SPSS version 21.0 program. The objective oral status was significantly lower in the experimental group than in the control group (t= -3.64, p<.001). There was no significant difference between the subjective oral status of the experimental group and control groups (t= -1.24, p=.109). Oral microorganism growth was significantly lower in the experimental group than in the control group (t= -7.39, p<.001). These findings indicate that special mouth care using an aroma solution could be an effective oral health nursing intervention for elderly patients with stroke.

  1. The Effects of Structured Physical Activity Program on Social Interaction and Communication for Children with Autism.

    PubMed

    Zhao, Mengxian; Chen, Shihui

    2018-01-01

    The purpose of this study was to investigate the effects of structured physical activity program on social interaction and communication of children with autism spectrum disorder (ASD). Fifty children with ASD from a special school were randomly divided into experimental and control groups. 25 children with ASD were placed in the experimental group, and the other 25 children as the control group participated in regular physical activity. A total of forty-one participants completed the study. A 12-week structured physical activity program was implemented with a total of 24 exercise sessions targeting social interaction and communication of children with ASD, and a quasi-experimental design was used for this study. Data were collected using quantitative and qualitative instruments. SSIS and ABLLS-R results showed that an overall improvement in social skills and social interaction for the experimental group across interim and posttests, F = 8.425, p = 0.001 ( p < 0.005), and significant improvements appeared in communication, cooperation, social interaction, and self-control subdomains ( p < 0.005). Conversely, no statistically significant differences were found in the control group ( p > 0.005). The study concluded that the special structured physical activity program positively influenced social interaction and communication skills of children with ASD, especially in social skills, communication, prompt response, and frequency of expression.

  2. Design and experimental realization of an optimal scheme for teleportation of an n-qubit quantum state

    NASA Astrophysics Data System (ADS)

    Sisodia, Mitali; Shukla, Abhishek; Thapliyal, Kishore; Pathak, Anirban

    2017-12-01

    An explicit scheme (quantum circuit) is designed for the teleportation of an n-qubit quantum state. It is established that the proposed scheme requires an optimal amount of quantum resources, whereas larger amount of quantum resources have been used in a large number of recently reported teleportation schemes for the quantum states which can be viewed as special cases of the general n-qubit state considered here. A trade-off between our knowledge about the quantum state to be teleported and the amount of quantum resources required for the same is observed. A proof-of-principle experimental realization of the proposed scheme (for a 2-qubit state) is also performed using 5-qubit superconductivity-based IBM quantum computer. The experimental results show that the state has been teleported with high fidelity. Relevance of the proposed teleportation scheme has also been discussed in the context of controlled, bidirectional, and bidirectional controlled state teleportation.

  3. Validation of the generalized model of two-phase thermosyphon loop based on experimental measurements of volumetric flow rate

    NASA Astrophysics Data System (ADS)

    Bieliński, Henryk

    2016-09-01

    The current paper presents the experimental validation of the generalized model of the two-phase thermosyphon loop. The generalized model is based on mass, momentum, and energy balances in the evaporators, rising tube, condensers and the falling tube. The theoretical analysis and the experimental data have been obtained for a new designed variant. The variant refers to a thermosyphon loop with both minichannels and conventional tubes. The thermosyphon loop consists of an evaporator on the lower vertical section and a condenser on the upper vertical section. The one-dimensional homogeneous and separated two-phase flow models were used in calculations. The latest minichannel heat transfer correlations available in literature were applied. A numerical analysis of the volumetric flow rate in the steady-state has been done. The experiment was conducted on a specially designed test apparatus. Ultrapure water was used as a working fluid. The results show that the theoretical predictions are in good agreement with the measured volumetric flow rate at steady-state.

  4. NASA Dryden's new in-house designed Propulsion Flight Test Fixture (PFTF) flew mated to a specially-

    NASA Technical Reports Server (NTRS)

    2001-01-01

    NASA Dryden Flight Research Center's new in-house designed Propulsion Flight Test Fixture (PFTF) is an airborne engine test facility that allows engineers to glean actual flight data on small experimental engines that would otherwise have to be gathered from traditional wind tunnels, ground test stands or laboratory setups. Now, with the 'captive carry' capability of the PFTF, new air-breathing propulsion schemes, such as Rocket Based Combined Cycle engines, can be economically flight-tested using sub-scale experiments. The PFTF flew mated to NASA Dryden's specially-equipped supersonic F-15B research aircraft during December 2001 and January 2002. The PFTF, carried on the F-15B's centerline attachment point, underwent in-flight checkout, known as flight envelope expansion, in order to verify its design and capabilities. Envelope expansion for the PFTF included envelope clearance, which involves maximum performance testing. Top speed of the F-15B with the PFTF is Mach 2.0. Other elements of envelope clearance are flying qualities assessment and flutter analysis. Airflow visualization of the PFTF and a 'stand-in' test engine was accomplished by attaching small tufts of nylon on them and videotaping the flow patterns revealed during flight. A surrogate experimental engine shape, called the cone tube, was flown attached to the force balance on the PFTF. The cone tube emulated the dimensional and mass properties of the maximum design load the PFTF can carry. As the F-15B put the PFTF and the attached cone tube through its paces, accurate data was garnered, allowing engineers to fully verify PFTF and force balance capabilities in real flight conditions. When the first actual experimental engine is ready to fly on the F-15B/PFTF, engineers will have full confidence and knowledge of what they can accomplish with this 'flying engine test stand.'

  5. The efficacy of a self-management programme for people with diabetes, after a special training programme for healthcare workers in Taiwan: a quasi-experimental design.

    PubMed

    Wu, Shu-Fang Vivienne; Liang, Shu-Yuan; Lee, Mei-Chen; Yu, Neng-Chun; Kao, Mu-Jung

    2014-09-01

    To analyse the efficacy of improving disease management after implementing a self-management programme for people with type 2 diabetes administered by healthcare workers who have received special training. The needs for diabetic care include increased training for healthcare providers to enhance their confidence and skills in managing patients, both physically and mentally. Quasi-experimental design. This study recruited participants from outpatient clinics in 10 hospitals in Taiwan. In 2010, purposive sampling was used to recruit 228 participants from two medical centres, five regional hospitals and three district hospitals. Participants were enrolled in a 'diabetes self-management programme' (watching patient videos, reading a diabetes self-care handbook, participating in four consultation courses of diabetes self-efficacy improvement, telephone follow-up and positive reinforcement). Efficacy analysis of post-test diabetes outcome variables of the experimental group was carried out. Sex, age and pretest score were used as the control variables for ancova test. Patients in the experimental group had significant improvement in body mass index (p < 0·01), waistline circumference (p < 0·001), haemoglobin A1C levels (p < 0·001), degrees of anxiety and depression (p < 0·001), self-efficacy (p < 0·001) and levels of self-care (p < 0·001). Self-efficacy of people with diabetes can be effectively improved by planned implementation of a 'diabetes self-management programme' by trained healthcare workers. The diabetes care professionals are provided the self-management programme to strengthen the awareness and importance of self-management in diabetes care. © 2013 John Wiley & Sons Ltd.

  6. Full area covered 3D profile measurement of special-shaped optics based on a new prototype non-contact profiler

    NASA Astrophysics Data System (ADS)

    Du, Hui-Lin; Zhou, Zhao-Zhong; Sun, Ze-Qing; Ju, Bing-Feng; Xu, Shaoning; Sun, Anyu

    2017-06-01

    A new prototype non-contact profiler based on surface tracking has been specially developed. Surface tracking is carried out by a specially designed dual stage probe system with the aid of a four-Degree Of Freedom high-precision motion platform. The dual stage probe system keeps a short-range optical probe constantly tracking the surface by a self-developed voice coil motor servo, by which a wide measuring range of up to 10 mm is realized. The system performance evaluation including resolution, repeatability, and scanning speed proved the good capability of the new prototype non-contact profiler. To realize a full area covered 3D profile measurement of special-shaped optics within one scanning procedure, a signal intensity monitor integrated in the surface tracking controller is specially developed. In the experiment, a snip-single-corner-rectangular-shaped freeform surface was successfully measured over full area by the new non-contact profiler. This work provides an effective solution for 3D profile measurement of special-shaped optical surfaces over full reflecting area. Experimental results demonstrate that the proposed measuring system is of great significance in quality evaluation of optical surfaces.

  7. Full area covered 3D profile measurement of special-shaped optics based on a new prototype non-contact profiler.

    PubMed

    Du, Hui-Lin; Zhou, Zhao-Zhong; Sun, Ze-Qing; Ju, Bing-Feng; Xu, Shaoning; Sun, Anyu

    2017-06-01

    A new prototype non-contact profiler based on surface tracking has been specially developed. Surface tracking is carried out by a specially designed dual stage probe system with the aid of a four-Degree Of Freedom high-precision motion platform. The dual stage probe system keeps a short-range optical probe constantly tracking the surface by a self-developed voice coil motor servo, by which a wide measuring range of up to 10 mm is realized. The system performance evaluation including resolution, repeatability, and scanning speed proved the good capability of the new prototype non-contact profiler. To realize a full area covered 3D profile measurement of special-shaped optics within one scanning procedure, a signal intensity monitor integrated in the surface tracking controller is specially developed. In the experiment, a snip-single-corner-rectangular-shaped freeform surface was successfully measured over full area by the new non-contact profiler. This work provides an effective solution for 3D profile measurement of special-shaped optical surfaces over full reflecting area. Experimental results demonstrate that the proposed measuring system is of great significance in quality evaluation of optical surfaces.

  8. Estimation of Hydrodynamic Impact Loads and Pressure Distributions on Bodies Approximating Elliptical Cylinders with Special Reference to Water Landings of Helicopters

    NASA Technical Reports Server (NTRS)

    Schnitzer, Emanuel; Hathaway, Melvin E

    1953-01-01

    An approximate method for computing water loads and pressure distributions on lightly loaded elliptical cylinders during oblique water impacts is presented. The method is of special interest for the case of emergency water landings of helicopters. This method makes use of theory developed and checked for landing impacts of seaplanes having bottom cross sections of V and scalloped contours. An illustrative example is given to show typical results obtained from the use of the proposed method of computation. The accuracy of the approximate method was evaluated through comparison with limited experimental data for two-dimensional drops of a rigid circular cylinder at a trim of 0 degrees and a flight -path angle of 90 degrees. The applicability of the proposed formulas to the design of rigid hulls is indicated by the rough agreement obtained between the computed and experimental results. A detailed computational procedure is included as an appendix.

  9. A Categorical Content Analysis of Highly Cited Literature Related to Trends and Issues in Special Education.

    PubMed

    Arden, Sarah V; Pentimonti, Jill M; Cooray, Rochana; Jackson, Stephanie

    2017-07-01

    This investigation employs categorical content analysis processes as a mechanism to examine trends and issues in a sampling of highly cited (100+) literature in special education journals. The authors had two goals: (a) broadly identifying trends across publication type, content area, and methodology and (b) specifically identifying articles with disaggregated outcomes for students with learning disabilities (LD). Content analyses were conducted across highly cited (100+) articles published during a 20-year period (1992-2013) in a sample ( n = 3) of journals focused primarily on LD, and in one broad, cross-categorical journal recognized for its impact in the field. Results indicated trends in the article type (i.e., commentary and position papers), content (i.e., reading and behavior), and methodology (i.e., small proportions of experimental and quasi-experimental designs). Results also revealed stability in the proportion of intervention research studies when compared to previous analyses and a decline in the proportion of those that disaggregated data specifically for students with LD.

  10. Flow-Rate-Pressure Characteristics of a Disk Blood Pump

    NASA Astrophysics Data System (ADS)

    Chernyavskii, A. M.; Medvedev, A. E.; Prikhodko, Yu. M.; Fomin, V. M.; Fomichev, V. P.; Fomichev, A. V.; Lomanovich, K. A.; Ruzmatov, T. M.; Karas‧kov, A. M.

    2017-11-01

    An experimental model of a disk pump for pumping a liquid has been designed and fabricated. This model was tested on a special stand with the use of a 40% aqueous solution of glycerin whose hydrodynamical characteristics most closely correspond to those of blood. The results obtained lend credence to the view that an implantable blood pump can be developed on the basis of the disk pump.

  11. Object's optical geometry measurements based on Extended Depth of Field (EDoF) approach

    NASA Astrophysics Data System (ADS)

    Szydłowski, Michał; Powałka, Bartosz; Chady, Tomasz; Waszczuk, Paweł

    2017-02-01

    The authors propose a method of using EDoF in macro inspections using bi-telecentric lenses and a specially designed experimental machine setup, allowing accurate focal distance changing. Also a software method is presented allowing EDoF image reconstruction using the continuous wavelet transform (CWT). Exploited method results are additionally compared with measurements performed with Keyence's LJ-V Series in-line Profilometer for reference matters.

  12. Influence of Punch Geometry on Process Parameters in Cold Backward Extrusion

    NASA Astrophysics Data System (ADS)

    Plančak, M.; Barišić, B.; Car, Z.; Movrin, D.

    2011-01-01

    In cold extrusion of steel tools make direct contact with the metal to be extruded. Those tools are exposed to high contact stresses which, in certain cases, may be limiting factors in applying this technology. The present paper was bound to the influence of punch head design on radial stress at the container wall in the process of cold backward extrusion. Five different punch head geometries were investigated. Radial stress on the container wall was measured by pin load cell technique. Special tooling for the experimental investigation was designed and made. Process has been analyzed also by FE method. 2D models of tools were obtained by UGS NX and for FE analysis Simufact Forming GP software was used. Obtained results (experimental and obtained by FE) were compared and analyzed. Optimal punch head geometry has been suggested.

  13. Strength and deformability of concrete beams reinforced by non-metallic fiber and composite rebar

    NASA Astrophysics Data System (ADS)

    Kudyakov, K. L.; Plevkov, V. S.; Nevskii, A. V.

    2015-01-01

    Production of durable and high-strength concrete structures with unique properties has always been crucial. Therefore special attention has been paid to non-metallic composite and fiber reinforcement. This article describes the experimental research of strength and deformability of concrete beams with dispersed and core fiber-based reinforcement. As composite reinforcement fiberglass reinforced plastic rods with diameters 6 mm and 10 mm are used. Carbon and basalt fibers are used as dispersed reinforcement. The developed experimental program includes designing and production of flexural structures with different parameters of dispersed fiber and composite rebar reinforcement. The preliminary testing of mechanical properties of these materials has shown their effectiveness. Structures underwent bending testing on a special bench by applying flexural static load up to complete destruction. During the tests vertical displacements were recorded, as well as value of actual load, slippage of rebars in concrete, crack formation. As a result of research were obtained structural failure and crack formation graphs, value of fracture load and maximum displacements of the beams at midspan. Analysis of experimental data showed the effectiveness of using dispersed reinforcement of concrete and the need for prestressing of fiberglass composite rebar.

  14. The 1985 Get Away Special Experimenter's Symposium

    NASA Technical Reports Server (NTRS)

    Thomas, L. R. (Editor); Mosier, F. L. (Editor)

    1986-01-01

    The 1985 Get Away Special (GAS) Experimenter's Symposium provided a formal opportunity for GAS experimenters to share the results of their projects. The focus is on payloads that have been flown on Shuttle missions, and on GAS payloads that will be flown in the near future.

  15. Quiet Clean Short Haul Experimental Engine

    NASA Image and Video Library

    1973-02-21

    Program manager Carl Ciepluch poses with a model of the Quiet Clean Short Haul Experimental Engine (QCSEE) conceived by the National Aeronautics and Space Administration (NASA) Lewis Research Center. The QCSEE engine was designed to power future short-distance transport aircraft without generating significant levels of noise or pollution and without hindering performance. The engines were designed to be utilized on aircraft operating from small airports with short runways. Lewis researchers investigated two powered-lift designs and an array of new technologies to deal with the shorter runways. Lewis contracted General Electric to design the two QCSEE engines—one with over-the-wing power-lift and one with an under-the-wing design. A scale model of the over-the-wing engine was tested in the Full Scale Tunnel at the Langley Research Center in 1975 and 1976. Lewis researchers investigated both versions in a specially-designed test stand, the Engine Noise Test Facility, on the hangar apron. The QCSEE engines met the goals set out by the NASA researchers. The aircraft industry, however, never built the short-distance transport aircraft for which the engines were intended. Different technological elements of the engine, however, were applied to some future General Electric engines.

  16. Experimental Design for Stochastic Models of Nonlinear Signaling Pathways Using an Interval-Wise Linear Noise Approximation and State Estimation

    PubMed Central

    Zimmer, Christoph

    2016-01-01

    Background Computational modeling is a key technique for analyzing models in systems biology. There are well established methods for the estimation of the kinetic parameters in models of ordinary differential equations (ODE). Experimental design techniques aim at devising experiments that maximize the information encoded in the data. For ODE models there are well established approaches for experimental design and even software tools. However, data from single cell experiments on signaling pathways in systems biology often shows intrinsic stochastic effects prompting the development of specialized methods. While simulation methods have been developed for decades and parameter estimation has been targeted for the last years, only very few articles focus on experimental design for stochastic models. Methods The Fisher information matrix is the central measure for experimental design as it evaluates the information an experiment provides for parameter estimation. This article suggest an approach to calculate a Fisher information matrix for models containing intrinsic stochasticity and high nonlinearity. The approach makes use of a recently suggested multiple shooting for stochastic systems (MSS) objective function. The Fisher information matrix is calculated by evaluating pseudo data with the MSS technique. Results The performance of the approach is evaluated with simulation studies on an Immigration-Death, a Lotka-Volterra, and a Calcium oscillation model. The Calcium oscillation model is a particularly appropriate case study as it contains the challenges inherent to signaling pathways: high nonlinearity, intrinsic stochasticity, a qualitatively different behavior from an ODE solution, and partial observability. The computational speed of the MSS approach for the Fisher information matrix allows for an application in realistic size models. PMID:27583802

  17. The 1987 Get Away Special Experimenter's Symposium

    NASA Technical Reports Server (NTRS)

    Barthelme, Neal (Editor); Mosier, Frances L. (Editor)

    1988-01-01

    The 1987 Get Away Special (GAS) Experimenter's symposium provides a formal opportunity for GAS Experimenter's to share the results of their projects. The focus of this symposium was on payloads that were flown on Shuttle missions, and on GAS payloads that will be flown in the future.

  18. 31 CFR Appendix A to Chapter V - Alphabetical Listing of Blocked Persons, Blocked Vessels, Specially Designated Nationals...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Alphabetical Listing of Blocked Persons, Blocked Vessels, Specially Designated Nationals, Specially Designated Terrorists, Specially Designated Global Terrorists, Foreign Terrorist Organizations, and Specially Designated Narcotics Traffickers (as of May 13, 2010) A Appendix A to Chapte...

  19. Methodological considerations in the design and implementation of clinical trials.

    PubMed

    Cirrincione, Constance T; Lavoie Smith, Ellen M; Pang, Herbert

    2014-02-01

    To review study design issues related to clinical trials led by oncology nurses, with special attention to those conducted within the cooperative group setting; to emphasize the importance of the statistician's role in the process of clinical trials. Studies available at clinicaltrials.gov using experimental designs that have been published in peer-reviewed journals; cooperative group trials are highlighted. The clinical trial is a primary means to test intervention efficacy. A properly designed and powered study with clear and measurable objectives is as important as the intervention itself. Collaboration among the study team, including the statistician, is central in developing and conducting appropriately designed studies. For optimal results, collaboration is an ongoing process that should begin early on. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. The Potential of Improving Medical Textile for Cutaneous Diseases

    NASA Astrophysics Data System (ADS)

    Radu, C. D.; Cerempei, A.; Salariu, M.; Parteni, O.; Ulea, E.; Campagne, Chr

    2017-10-01

    The paper dwells on the prospect of medical textiles designed to release a drug/active principle to the dermis of patients suffering from cutaneous disease (allergic dermatitis, psoriasis, bacterial/infectious conditions and inflammatory conditions). The paper is an overview of general and experimental data from textile applications. An adequate medical textile may have a cellulosic structure, mainly knitted cotton fabric. In special cases, one may use woven fabric for multilayer drug-releasing systems. As far as controlled release systems are concerned, we carried out a critical comparison between the systems described in literature and our experimental findings as concerns cyclodextrin, hydrogel, film charged with active principles and multilayer system.

  1. DESIGN AND HAZARDS SUMMARY REPORT, BOILING REACTOR EXPERIMENT V (BORAX V)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1961-05-01

    Design data for BORAX V are presented along with results of hazards evaluation studies. Considcration of the hazards associated with the operation of BORAX V was based on the following conditions: For normal steady-state power and experimental operation, the reactor and plant are adequately shielded and ventilated to allow personnel to be safely stationed in the turbine building and on the main floor of the reactor building. The control building is located one- half mile distant from the reactor building. For special, hazardous experiments, personnel are withdrawn from the reactor area. (M.C.G.)

  2. Methods of high current magnetic field generator for transcranial magnetic stimulation application

    NASA Astrophysics Data System (ADS)

    Bouda, N. R.; Pritchard, J.; Weber, R. J.; Mina, M.

    2015-05-01

    This paper describes the design procedures and underlying concepts of a novel High Current Magnetic Field Generator (HCMFG) with adjustable pulse width for transcranial magnetic stimulation applications. This is achieved by utilizing two different switching devices, the MOSFET and insulated gate bipolar transistor (IGBT). Results indicate that currents as high as ±1200 A can be generated with inputs of +/-20 V. Special attention to tradeoffs between field generators utilizing IGBT circuits (HCMFG1) and MOSFET circuits (HCMFG2) was considered. The theory of operation, design, experimental results, and electronic setup are presented and analyzed.

  3. Methods of high current magnetic field generator for transcranial magnetic stimulation application

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bouda, N. R., E-mail: nybouda@iastate.edu; Pritchard, J.; Weber, R. J.

    This paper describes the design procedures and underlying concepts of a novel High Current Magnetic Field Generator (HCMFG) with adjustable pulse width for transcranial magnetic stimulation applications. This is achieved by utilizing two different switching devices, the MOSFET and insulated gate bipolar transistor (IGBT). Results indicate that currents as high as ±1200 A can be generated with inputs of +/−20 V. Special attention to tradeoffs between field generators utilizing IGBT circuits (HCMFG{sub 1}) and MOSFET circuits (HCMFG{sub 2}) was considered. The theory of operation, design, experimental results, and electronic setup are presented and analyzed.

  4. The in vivo wear resistance of 12 composite resins.

    PubMed

    Lang, B R; Bloem, T J; Powers, J M; Wang, R F

    1992-09-01

    The in vivo wear resistance of 12 composite resins were compared with an amalgam control using the Latin Square experimental design. Sixteen edentulous patients wearing specially designed complete dentures formed the experimental population. The Michigan Computer Graphics Measurement System was used to digitize the surface of the control and composite resin samples before and after 3-month test periods to obtain wear data. The 12 composite resins selected for this investigation based on their published composite classification types were seven fine particle composites, three blends, and two microfilled composite resins. The Latin Square experimental design was found to be valid with the factor of material being statistically different at the 5% level of significance. Wear was computed as volume loss (mm3/mm2), and all of the composites studied had more wear than the amalgam control (P = .001). After 3 months, the mean (error) of wear of the amalgam was 0.028 (0.006). Means (error) of wear for the 12 composites were ranked from most to least wear by mean wear volume loss. The absence of any relationship between mean wear volume loss and the volume percentage filler was confirmed by the correlation coefficient r = -0.158.

  5. The promise of a specially-designed graft copolymer of acrylic acid onto cellulose as selective sorbent for heavy metal ions.

    PubMed

    Essawy, Hisham A; Mohamed, Magdy F; Ammar, Nabila S; Ibrahim, Hanan S

    2017-10-01

    A specially-designed graft copolymer of acrylic acid onto in-situ formed cellulose-fulvate hybrid showed privileged tendency for uptake of Pb(II) during competitive removal from a mixture containing Cd(II) and Ni(II) within 5min at pH 5. This novel trend is attributed mainly to the crowded high content of coordinating centers within the designed graft copolymer along with the acquired superabsorbency. This provides an outstanding tool to separate some metal ions selectively from mixtures containing multiple ions on kinetic basis. Thus, the designed graft copolymer structure exhibited superior efficiency that reached ∼95% for sole removal of Pb(II). Kinetic modeling for Pb(II) individual removal showed excellent fitting with a pseudo second-order model. Intraparticle diffusion model on the other hand ensured governance of boundary layer effect over diffusion during the removal process due to the superabsorbency feature of the graft copolymer. The experimental findings were described with models such as Freundlich, Langmuir, and Dubinin-Radushkevich. The Langmuir and Freundlich models showed convenience with the adsorption isotherm of Pb(II) onto the developed graft copolymer. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Ray trace visualization of negative refraction of light in two-dimensional air-bridged silicon photonic crystal slabs at 1.55 microm.

    PubMed

    Gan, Lin; Liu, Ya-Zhao; Li, Jiang-Yan; Zhang, Ze-Bo; Zhang, Dao-Zhong; Li, Zhi-Yuan

    2009-06-08

    We demonstrate design, fabrication, and ray trace observation of negative refraction of near-infrared light in a two-dimensional square lattice of air holes etched into an air-bridged silicon slab. Special surface morphologies are designed to reduce the impedance mismatch when light refracts from a homogeneous silicon slab into the photonic crystal slab. We clearly observed negative refraction of infrared light for TE-like modes in a broad wavelength range by using scanning near-field optical microscopy technology. The experimental results are in good agreement with finite-difference time-domain simulations. The results indicate the designed photonic crystal structure can serve as polarization beam splitter.

  7. Final Report to the Office of Naval Research

    DTIC Science & Technology

    1991-10-18

    microparticles suspended in the water. The main objective of the research was to develop, and experimentally verify, a theoretical model for the Laser Doppler (LD...components). This design allows great flexibility for positioning and scanning the laser beam in the water. (2) Special polystyrene microparticles were used...in the experiments. These microparticles were very uniform in shape (spherical) and size. Three different sizes were used - 0.1pm, lpm and 10pm radius

  8. Considerations for Integrating Women into Closed Occupations in the U.S. Special Operations Forces

    DTIC Science & Technology

    2015-05-01

    effectiveness of integration. Ideally, studies adopting an experimental design (using both test and control groups ) would be preferred, but sample sizes may...data -- a survey of SOF personnel and a series of focus group discussions -- collected by the research team regarding the potential challenges to... controlled positions. This report summarizes our research , analysis, and conclusions. We used a mixed-methods approach. We reviewed the current state of

  9. The Effects of Structured Physical Activity Program on Social Interaction and Communication for Children with Autism

    PubMed Central

    Zhao, Mengxian

    2018-01-01

    The purpose of this study was to investigate the effects of structured physical activity program on social interaction and communication of children with autism spectrum disorder (ASD). Fifty children with ASD from a special school were randomly divided into experimental and control groups. 25 children with ASD were placed in the experimental group, and the other 25 children as the control group participated in regular physical activity. A total of forty-one participants completed the study. A 12-week structured physical activity program was implemented with a total of 24 exercise sessions targeting social interaction and communication of children with ASD, and a quasi-experimental design was used for this study. Data were collected using quantitative and qualitative instruments. SSIS and ABLLS-R results showed that an overall improvement in social skills and social interaction for the experimental group across interim and posttests, F = 8.425, p = 0.001 (p < 0.005), and significant improvements appeared in communication, cooperation, social interaction, and self-control subdomains (p < 0.005). Conversely, no statistically significant differences were found in the control group (p > 0.005). The study concluded that the special structured physical activity program positively influenced social interaction and communication skills of children with ASD, especially in social skills, communication, prompt response, and frequency of expression. PMID:29568743

  10. 78 FR 36084 - Special Conditions: Cirrus Design Corporation Model SF50 Airplane; Function and Reliability...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-17

    ...; Special Conditions No. 23-248-SC] Special Conditions: Cirrus Design Corporation Model SF50 Airplane... granting special conditions for the Cirrus Design Corporation model SF50 airplane. We are withdrawing... Special Condition No. 23-248- SC for the Cirrus Design Corporation new model SF50 ``Vision'' Jet. The SF50...

  11. Linguistic attention control: attention shifting governed by grammaticized elements of language.

    PubMed

    Taube-Schiff, Marlene; Segalowitz, Norman

    2005-05-01

    In 2 experiments, the authors investigated attention control for tasks involving the processing of grammaticized linguistic stimuli (function words) contextualized in sentence fragments. Attention control was operationalized as shift costs obtained with adult speakers of English in an alternating-runs experimental design (R. D. Rogers & S. Monsell, 1995). Experiment 1 yielded significant attention shift costs between tasks involving judgments about the meanings of grammatical function words. The authors used a 3-stage experimental design (G. Wylie & A. Allport, 2000), and the emerging pattern of results implicated task set reconfiguration and not task set inertia in these shift costs. Experiment 2 further demonstrated that shift costs were lower when the tasks involved shared attentional resources (processing the same grammatical dimension) versus unshared resources (different grammatical dimensions). The authors discuss the results from a cognitive linguistic perspective and for their implications for the view that language itself can serve a special attention-directing function.

  12. A comparison of the effects of a special gynaecological garment and music in reducing the anxiety related to gynaecological examination.

    PubMed

    Kocabaş, Pembegül; Khorshid, Leyla

    2012-03-01

    To investigate the effect of a special gynaecological garment and music plus the special gynaecological garment on reducing the state anxiety related to gynaecological examination. Gynaecological examination is one of the most common anxiety-producing medical procedures and causes embarrassment and discomfort. Few studies have focused on the effect of a gynaecological garment on anxiety associated with gynaecological examinations. The patients were allocated to one of three groups, one control and two experimental. While the patients in the control group were subjected to the normal outpatient procedure, the patients in the first experimental group were dressed in a special gynaecological garment. In the control group, gynaecological examinations were performed with a traditional one-piece drape. In addition to wearing the special gynaecological garment, the women in the garment + music group listened to music during the gynaecological examination. The State Anxiety Inventory Form was applied to the patients in all three groups before and after gynaecological examination. The state anxiety level after gynaecological examination in patients in the control group was found to be higher, but it was found to be lower in patients in both the first experimental group (garment) and the second experimental group (garment + music). The state anxiety level was found to be more reduced in the experimental groups than in the control group. The state anxiety level after gynaecological examination was found to be higher in single patients in the second experimental group. The special gynaecological garments are effective in reducing the state anxiety associated with gynaecological examination. It should be taken into consideration that women perceived state anxiety during the gynaecological examinations. To allay anxiety associated with gynaecological examination in women, a special garment may be considered. © 2011 Blackwell Publishing Ltd.

  13. Animals in biomedical space research

    NASA Astrophysics Data System (ADS)

    Phillips, Robert W.

    The use of experimental animals has been a major component of biomedical research progress. Using animals in space presents special problems, but also provides special opportunities. Rat and squirrel monkeys experiments have been planned in concert with human experiments to help answer fundamental questions concerning the effect of weightlessness on mammalian function. For the most part, these experiments focus on identified changes noted in humans during space flight. Utilizing space laboratory facilities, manipulative experiments can be completed while animals are still in orbit. Other experiments are designed to study changes in gravity receptor structure and function and the effect of weightlessness on early vertebrate development. Following these preliminary animals experiments on Spacelab Shuttle flights, longer term programs of animal investigation will be conducted on Space Station.

  14. Misconceptions in recent papers on special relativity and absolute space theories

    NASA Technical Reports Server (NTRS)

    Torr, D. G.; Kolen, P.

    1982-01-01

    Several recent papers which purport to substantiate or negate arguments in favor of certain theories of absolute space have been based on fallacious principles. This paper discusses three related instances, indicating where misconceptions have arisen. It is established, contrary to popular belief, that the classical Lorentz ether theory accounts for all the experimental evidence which supports the special theory of relativity. It is demonstrated that the ether theory predicts the null results obtained from pulsar timing and Moessbauer experiments. It is concluded that a measurement of the one-way velocity of light has physical meaning within the context of the Lorentz theory, and it is argued that an adequately designed experiment to measure the one-way velocity of light should be attempted.

  15. Rational design of liposomal drug delivery systems, a review: Combined experimental and computational studies of lipid membranes, liposomes and their PEGylation.

    PubMed

    Bunker, Alex; Magarkar, Aniket; Viitala, Tapani

    2016-10-01

    Combined experimental and computational studies of lipid membranes and liposomes, with the aim to attain mechanistic understanding, result in a synergy that makes possible the rational design of liposomal drug delivery system (LDS) based therapies. The LDS is the leading form of nanoscale drug delivery platform, an avenue in drug research, known as "nanomedicine", that holds the promise to transcend the current paradigm of drug development that has led to diminishing returns. Unfortunately this field of research has, so far, been far more successful in generating publications than new drug therapies. This partly results from the trial and error based methodologies used. We discuss experimental techniques capable of obtaining mechanistic insight into LDS structure and behavior. Insight obtained purely experimentally is, however, limited; computational modeling using molecular dynamics simulation can provide insight not otherwise available. We review computational research, that makes use of the multiscale modeling paradigm, simulating the phospholipid membrane with all atom resolution and the entire liposome with coarse grained models. We discuss in greater detail the computational modeling of liposome PEGylation. Overall, we wish to convey the power that lies in the combined use of experimental and computational methodologies; we hope to provide a roadmap for the rational design of LDS based therapies. Computational modeling is able to provide mechanistic insight that explains the context of experimental results and can also take the lead and inspire new directions for experimental research into LDS development. This article is part of a Special Issue entitled: Biosimulations edited by Ilpo Vattulainen and Tomasz Róg. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. AN EXPERIMENTAL CURRICULUM FOR YOUNG MENTALLY RETARDED CHILDREN. TC SERIES IN SPECIAL EDUCATION.

    ERIC Educational Resources Information Center

    CONNOR, FRANCES P.; TALBOT, MABEL E.

    THIS CURRICULUM REPORT IS A DESCRIPTION OF A SPECIAL EDUCATION PROGRAM FOR PRESCHOOL EDUCABLE MENTALLY RETARDED CHILDREN, TOGETHER WITH AN ACCOUNT OF ITS DEVELOPMENT IN EXPERIMENTAL CLASSES IN NEW YORK CITY. THE EXPERIMENTAL CURRICULUM WAS THE INDEPENDENT VARIABLE OF A RESEARCH PROJECT TO STUDY THE EFFECTS OF GROUP EXPERIENCE UPON YOUNG…

  17. Summary Report of the Summer Conference of the DARPA-Materials Research Council Held in La Jolla, California on 6-30 July 1987

    DTIC Science & Technology

    1987-07-01

    that any array detector have very broad dynamic range. iv.) Analytical methods used in extracting structural data from experimental observations from...important influence on magnet design and on specialized magnetic devices ( SQUID devices) and forms the basis for promising electronic devices ’Josephson...printable inks using 123 powders. (2) Control of interfacial reactions between the superconductors and the dielectric. (3) Development of suitable

  18. Gas/Surface Interaction Study Applied to Si-based Materials Used in Driven Micro- and Nano-scale Devices

    DTIC Science & Technology

    2010-01-01

    science and engineering. For example, by measuring the frequency shift of sensor oscillations, one can measure gas adsorption on the sensor surface...free-molecular regime with varied gas pressure. The measurement path of the experimental setup is schematically shown in Fig. 3.1. The sensor is...excited by the electric field between the sensor and fixed electrode by means of a specially designed system of self-induced oscillations. The

  19. The effect of added fullness and ventilation holes in T-shirt design on thermal comfort.

    PubMed

    Ho, Chupo; Fan, Jintu; Newton, Edward; Au, Raymond

    2011-04-01

    This paper reports on an experimental investigation on the effect of added fullness and ventilation holes in T-shirt design on clothing comfort measured in terms of thermal insulation and moisture vapour resistance. Four T-shirts in four different sizes (S, M, L, XL) were cut under the traditional sizing method while another (F-1) was cut with specially added fullness to create a 'flared' drape. A thermal manikin 'Walter' was used to measure the thermal insulation and moisture vapour resistance of the T-shirts in a chamber with controlled temperature, relative humidity and air velocity. The tests included four conditions: manikin standing still in the no-wind and windy conditions and walking in the no-wind and windy condition. It was found that adding fullness in the T-shirt design (F-1) to create the 'flared' drape can significantly reduce the T-shirt's thermal insulation and moisture vapour resistance under walking or windy conditions. Heat and moisture transmission through the T-shirt can be further enhanced by creating small apertures on the front and back of the T-shirt with specially added fullness. STATEMENT OF RELEVANCE: The thermal comfort of the human body is one of the key issues in the study of ergonomics. When doing exercise, a human body will generate heat, which will eventually result in sweating. If heat and moisture are not released effectively from the body, heat stress may occur and the person's performance will be negatively affected. Therefore, contemporary athletic T-shirts are designed to improve the heat and moisture transfer from the wearer. Through special cutting, such athletic T-shirts can be designed to improve the ventilation of the wearer.

  20. Experimental Investigation of Thermal Conductivity of Meat During Freezing

    NASA Astrophysics Data System (ADS)

    Shinbayeva, A.; Arkharov, I.; Aldiyarov, A.; Drobyshev, A.; Zhubaniyazova, M.; Kurnosov, V.

    2017-04-01

    The cryogenic technologies of processing and storage of agricultural products are becoming increasingly indispensable in the food industry as an important factor of ensuring food safety. One of such technologies is the shock freezing of meat, which provides a higher degree of preservation of the quality of frozen products in comparison with traditional technologies. The thermal conductivity of meat is an important parameter influencing the energy consumption in the freezing process. This paper presents the results of an experimental investigation of the temperature dependence of the thermal conductivity of beef. The measurements were taken by using a specially designed measurement cell, which allows covering the temperature range from 80 to 300 K.

  1. Kinematical Test Theories for Special Relativity

    NASA Astrophysics Data System (ADS)

    Lämmerzahl, Claus; Braxmaier, Claus; Dittus, Hansjörg; Müller, Holger; Peters, Achim; Schiller, Stephan

    A comparison of certain kinematical test theories for Special Relativity including the Robertson and Mansouri-Sext test theories is presented and the accuracy of the experimental results testing Special Relativity are expressed in terms of the parameters appearing in these test theories. The theoretical results are applied to the most precise experimental results obtained recently for the isotropy of light propagation and the constancy of the speed of light.

  2. DEVELOPMENT OF IMPROVED FABRICATION METHODS, PROCESS AND TECHNIQUES FOR PRODUCING TYPICAL AIRCRAFT SHAPES FROM BERYLLIUM. Interim Technical Documentary Progress Report for the Period ending October 31, 1962

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jenkins, R.G.; Siergiej, J.M.

    1962-12-28

    In a program to develop a complete manufacturing process for ihe production of beryllium channels, techniques are being sought for drawing to obtain a flnal product meeting specifications more rigorous than are obtainable by direct extrusion. Progress in designing and procuring the special tooling required to draw complex shapes at elevated temperature is described, and the flrst set of draw dies is evaluated with respect to design and quality. Three experimental draw attempts have been made on U-channels, in addition to draw tests on flats. (auth)

  3. Vacuum generation in pneumatic artificial heart drives with a specially designed ejector system.

    PubMed

    Schima, H; Huber, L; Spitaler, F

    1990-06-01

    To improve the filling characteristics of pneumatically driven membrane artificial hearts (AHs), a vacuum is applied during diastole. This paper describes an ejector system for AH-drivers based on the Venturi effect, which was designed for this purpose. It provides vacuums of more than -40 mmHg at flow rates up to 50 l/min requiring a supplying primary gas pressure of less than 150 kPa (1140 mmHg). Under normal working conditions, the necessary supply flow was less than 5l/min. The device is small, cheap, quiet and fail-safe, and has been evaluated successfully in experimental and clinical use.

  4. POROUS ALUMINOPHOSPHATES :From Molecular Sieves to Designed Acid Catalysts

    NASA Astrophysics Data System (ADS)

    Pastore, H. O.; Coluccia, S.; Marchese, L.

    2005-08-01

    This review covers the synthesis, characterization, and physico-chemical properties of microporous and mesoporous aluminophosphates and silicoaluminophosphates molecular sieves. Particular emphasis is given to the materials that have found applications as acid catalysts. We consider the evolution of the synthesis procedures from the first discoveries to the current methodologies and give perspectives for new possible synthesis strategies. Emphasis is given to the use of specially prepared precursors/reactants designed for the use as molecular sieves. Experimental (especially MAS-NMR and FTIR spectroscopy) and theoretical approaches to the description of the Si insertion into the ALPO framework and to the acidic properties of SAPOs and MeAPSOs materials are discussed.

  5. FPGA implementation of ICA algorithm for blind signal separation and adaptive noise canceling.

    PubMed

    Kim, Chang-Min; Park, Hyung-Min; Kim, Taesu; Choi, Yoon-Kyung; Lee, Soo-Young

    2003-01-01

    An field programmable gate array (FPGA) implementation of independent component analysis (ICA) algorithm is reported for blind signal separation (BSS) and adaptive noise canceling (ANC) in real time. In order to provide enormous computing power for ICA-based algorithms with multipath reverberation, a special digital processor is designed and implemented in FPGA. The chip design fully utilizes modular concept and several chips may be put together for complex applications with a large number of noise sources. Experimental results with a fabricated test board are reported for ANC only, BSS only, and simultaneous ANC/BSS, which demonstrates successful speech enhancement in real environments in real time.

  6. Publication Trends in Model Organism Research

    PubMed Central

    Dietrich, Michael R.; Ankeny, Rachel A.; Chen, Patrick M.

    2014-01-01

    In 1990, the National Institutes of Health (NIH) gave some organisms special status as designated model organisms. This article documents publication trends for these NIH-designated model organisms over the past 40 years. We find that being designated a model organism by the NIH does not guarantee an increasing publication trend. An analysis of model and nonmodel organisms included in GENETICS since 1960 does reveal a sharp decline in the number of publications using nonmodel organisms yet no decline in the overall species diversity. We suggest that organisms with successful publication records tend to share critical characteristics, such as being well developed as standardized, experimental systems and being used by well-organized communities with good networks of exchange and methods of communication. PMID:25381363

  7. Design of PCB search coils for AC magnetic flux density measurement

    NASA Astrophysics Data System (ADS)

    Ulvr, Michal

    2018-04-01

    This paper presents single-layer, double-layer and ten-layer planar square search coils designed for AC magnetic flux density amplitude measurement up to 1 T in the low frequency range in a 10 mm air gap. The printed-circuit-board (PCB) method was used for producing the search coils. Special attention is given to a full characterization of the PCB search coils including a comparison between the detailed analytical design method and the finite integration technique method (FIT) on the one hand, and experimental results on the other. The results show very good agreement in the resistance, inductance and search coil constant values (the area turns) and also in the frequency dependence of the search coil constant.

  8. Ensuring the Quality of Evidence: Using the Best Design to Answer Health IT Questions.

    PubMed

    Weir, Charlene R

    2016-01-01

    The quality of logic in a research design determines the value of the results and our confidence regarding the validity of the findings. The purpose of this contribution is to review the principles of research design as they apply to research and evaluation in health IT. We review the architecture of research design, the definitions of cause, sources of bias and confounds, and the importance of measurement as related to the various types of health IT questions. The goal is to provide practitioners a roadmap for making decisions for their own specific study. The contribution is organized around the Threats to Validity taxonomy and explains how different design models address these threats through the use of blocking, factorial design, control groups and time series analysis. The contribution discusses randomized experiments, and includes regression discontinuity designs and various quasi-experimental designs with a special emphasis on how to improve pre/post designs. At the end, general recommendations are provided for improving weaker designs and general research procedures.

  9. Theoretical and experimental investigations on high peak power Q-switched Nd:YAG laser at 1112 nm

    NASA Astrophysics Data System (ADS)

    He, Miao; Yang, Feng; Wang, Zhi-Chao; Gao, Hong-Wei; Yuan, Lei; Li, Chen-Long; Zong, Nan; Shen, Yu; Bo, Yong; Peng, Qin-Jun; Cui, Da-Fu; Xu, Zu-Yan

    2018-07-01

    We report on the experimental measurement and theoretical analysis on a Q-switched high peak power laser diode (LD) side-pumped 1112 nm Nd:YAG laser by means of special mirrors coating design in cavity. In theory, a numerical model, based on four-wavelength rate equations, is performed to analyze the competition process of different gain lines and the output characteristics of the Q-switched Nd:YAG laser. In the experiment, a maximum output power of 25.2 W with beam quality factor M2 of 1.46 is obtained at the pulse repetition rate of 2 kHz and 210 ns of pulse width, corresponding to a pulse energy and peak power of 12.6 mJ and 60 kW, respectively. The experimental data agree well with the theoretical simulation results.

  10. Editorial: Special Issue on Experimental Vibration Analysis

    NASA Astrophysics Data System (ADS)

    Serra, Roger

    2018-04-01

    The vibratory analyses are particularly present today in the various fields of industry, from aeronautics to manufacturing, from machining and maintenance to civil engineering, to mention a few areas, which have made this special issue a true need. The International Journal of Mechanics & Industry compiles a Special Issue on Experimental Vibration Analysis. More than thirty manuscripts were received by the international scientific committee on the 6th congress AVE2016 and only eight papers have been selected after completing a careful and rigorous peer-review process for the Special Issue, which are briefly summarized below.

  11. 77 FR 36419 - Feasibility of Enumerating “Specially Designed” Components

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ... feasibility of positively identifying ``specially designed'' ``components'' on the Commerce Control List (CCL... exhaustive lists of the ``specially designed'' ``components'' referred to in certain Export Control... project involving minimizing the use of the term ``specially designed'' on the current Commerce Control...

  12. Candidate molten salt investigation for an accelerator driven subcritical core

    NASA Astrophysics Data System (ADS)

    Sooby, E.; Baty, A.; Beneš, O.; McIntyre, P.; Pogue, N.; Salanne, M.; Sattarov, A.

    2013-09-01

    We report a design for accelerator-driven subcritical fission in a molten salt core (ADSMS) that utilizes a fuel salt composed of NaCl and transuranic (TRU) chlorides. The ADSMS core is designed for fast neutronics (28% of neutrons >1 MeV) to optimize TRU destruction. The choice of a NaCl-based salt offers benefits for corrosion, operating temperature, and actinide solubility as compared with LiF-based fuel salts. A molecular dynamics (MD) code has been used to estimate properties of the molten salt system which are important for ADSMS design but have never been measured experimentally. Results from the MD studies are reported. Experimental measurements of fuel salt properties and studies of corrosion and radiation damage on candidate metals for the core vessel are anticipated. A special thanks is due to Prof. Paul Madden for introducing the ADSMS group to the concept of using the molten salt as the spallation target, rather than a conventional heavy metal spallation target. This feature helps to optimize this core as a Pu/TRU burner.

  13. Evaluation of hospital palliative care teams: strengths and weaknesses of the before-after study design and strategies to improve it.

    PubMed

    Simon, S; Higginson, I J

    2009-01-01

    Hospital palliative care teams (HPCTs) are well established as multi-professional services to provide palliative care in an acute hospital setting and are increasing in number. However, there is still limited evaluation of them, in terms of efficacy and effectiveness. The gold standard method of evaluation is a randomised control trial, but because of methodological (e.g., randomisation), ethical and practical difficulties such trials are often not possible. HPCT is a complex intervention, and the specific situation in palliative care makes it challenging to evaluate (e.g., distress and cognitive impairment of patients). The quasi-experimental before-after study design has the advantage of enabling an experimental character without randomisation. But this has other weaknesses and is prone to bias, for example, temporal trends and selection bias. As for every study design, avoidance and minimisation of bias is important to improve validity. Therefore, strategies of selecting an appropriate control group or time series and applying valid outcomes and measurement tools help reducing bias and strengthen the methods. Special attention is needed to plan and define the design and applied method.

  14. Design of advanced ultrasonic transducers for welding devices.

    PubMed

    Parrini, L

    2001-11-01

    A new high frequency ultrasonic transducer has been conceived, designed, prototyped, and tested. In the design phase, an advanced approach was used and established. The method is based on an initial design estimate obtained with finite element method (FEM) simulations. The simulated ultrasonic transducers and resonators are then built and characterized experimentally through laser interferometry and electrical resonance spectra. The comparison of simulation results with experimental data allows the parameters of FEM models to be adjusted and optimized. The achieved FEM simulations exhibit a remarkably high predictive potential and allow full control of the vibration behavior of the transducer. The new transducer is mounted on a wire bonder with a flange whose special geometry was calculated by means of FEM simulations. This flange allows the transducer to be attached on the wire bonder, not only in longitudinal nodes, but also in radial nodes of the ultrasonic field excited in the horn. This leads to a total decoupling of the transducer to the wire bonder, which has not been achieved so far. The new approach to mount ultrasonic transducers on a welding device is of major importance, not only for wire bonding, but also for all high power ultrasound applications and has been patented.

  15. Estimating Information Processing in a Memory System: The Utility of Meta-analytic Methods for Genetics.

    PubMed

    Yildizoglu, Tugce; Weislogel, Jan-Marek; Mohammad, Farhan; Chan, Edwin S-Y; Assam, Pryseley N; Claridge-Chang, Adam

    2015-12-01

    Genetic studies in Drosophila reveal that olfactory memory relies on a brain structure called the mushroom body. The mainstream view is that each of the three lobes of the mushroom body play specialized roles in short-term aversive olfactory memory, but a number of studies have made divergent conclusions based on their varying experimental findings. Like many fields, neurogenetics uses null hypothesis significance testing for data analysis. Critics of significance testing claim that this method promotes discrepancies by using arbitrary thresholds (α) to apply reject/accept dichotomies to continuous data, which is not reflective of the biological reality of quantitative phenotypes. We explored using estimation statistics, an alternative data analysis framework, to examine published fly short-term memory data. Systematic review was used to identify behavioral experiments examining the physiological basis of olfactory memory and meta-analytic approaches were applied to assess the role of lobular specialization. Multivariate meta-regression models revealed that short-term memory lobular specialization is not supported by the data; it identified the cellular extent of a transgenic driver as the major predictor of its effect on short-term memory. These findings demonstrate that effect sizes, meta-analysis, meta-regression, hierarchical models and estimation methods in general can be successfully harnessed to identify knowledge gaps, synthesize divergent results, accommodate heterogeneous experimental design and quantify genetic mechanisms.

  16. The study of human higher mental functions as they relate to neurophysiological processes and personal characteristics

    NASA Astrophysics Data System (ADS)

    Runnova, Anastasiya; Zhuravlev, Maxim; Kulanin, Roman; Protasov, Pavel; Hramov, Alexander; Koronovskii, Alexey

    2018-02-01

    In this paper we study the correlation between the neurophysiological processes and personal characteristics arising in the processes of human higher mental functions. We find that the activity of the brain correlates with the results of psychological tests (according to the Cattell test). Experimental studies and math processing are described for operation design with the registration of human multi-channel EEG data in two phases (the processes of passive wakefulness (background) and special psychological testing (active phase)).

  17. Introduction to GRASP - General rotorcraft aeromechanical stability program - A modern approach to rotorcraft modeling

    NASA Technical Reports Server (NTRS)

    Hodges, D. H.; Hopkins, A. S.; Kunz, D. L.; Hinnant, H. E.

    1986-01-01

    The General Rotorcraft Aeromechanical Stability Program (GRASP), which is a hybrid between finite element programs and spacecraft-oriented multibody programs, is described in terms of its design and capabilities. Numerical results from GRASP are presented and compared with the results from an existing, special-purpose coupled rotor/body aeromechanical stability program and with experimental data of Dowell and Traybar (1975 and 1977) for large deflections of an end-loaded cantilevered beam. The agreement is excellent in both cases.

  18. NUCLEON Satellite Mission. Status and Plans

    NASA Technical Reports Server (NTRS)

    Bashindzhagyan, G.; Adams, J.; Bashindzhagyan, P.; Baranova, N.; Christl, M.; Chilingarian, A.; Chupin, I.; Derrickson, J.; Drury, L.; Egorov, N.

    2003-01-01

    The main objective of the NUCLEON satellite mission is direct measurements of the elemental energy spectra of high-energy (10(exp 11) - 10(exp 15) eV) cosmic rays with Kinematic Lightweight Energy Meter (KLEM) device. The design of the instrument has been corrected to increase geometry factor and improve charge resolution. The special mechanical and electronic systems have been developed for installation of the experimental apparatus in a regular Russian satellite. It is planned to launch the NUCLEON instrument in 2006.

  19. 31 CFR 594.310 - Specially designated global terrorist; SDGT.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Specially designated global terrorist... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS General Definitions § 594.310 Specially designated global terrorist; SDGT. The term specially...

  20. 31 CFR 594.310 - Specially designated global terrorist; SDGT.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Specially designated global terrorist... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS General Definitions § 594.310 Specially designated global terrorist; SDGT. The term specially...

  1. 31 CFR 594.310 - Specially designated global terrorist; SDGT.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Specially designated global terrorist... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS General Definitions § 594.310 Specially designated global terrorist; SDGT. The term specially...

  2. 31 CFR 594.310 - Specially designated global terrorist; SDGT.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Specially designated global terrorist... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS General Definitions § 594.310 Specially designated global terrorist; SDGT. The term specially...

  3. 31 CFR 594.310 - Specially designated global terrorist; SDGT.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Specially designated global terrorist... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS General Definitions § 594.310 Specially designated global terrorist; SDGT. The term specially...

  4. Multi-objective experimental design for (13)C-based metabolic flux analysis.

    PubMed

    Bouvin, Jeroen; Cajot, Simon; D'Huys, Pieter-Jan; Ampofo-Asiama, Jerry; Anné, Jozef; Van Impe, Jan; Geeraerd, Annemie; Bernaerts, Kristel

    2015-10-01

    (13)C-based metabolic flux analysis is an excellent technique to resolve fluxes in the central carbon metabolism but costs can be significant when using specialized tracers. This work presents a framework for cost-effective design of (13)C-tracer experiments, illustrated on two different networks. Linear and non-linear optimal input mixtures are computed for networks for Streptomyces lividans and a carcinoma cell line. If only glucose tracers are considered as labeled substrate for a carcinoma cell line or S. lividans, the best parameter estimation accuracy is obtained by mixtures containing high amounts of 1,2-(13)C2 glucose combined with uniformly labeled glucose. Experimental designs are evaluated based on a linear (D-criterion) and non-linear approach (S-criterion). Both approaches generate almost the same input mixture, however, the linear approach is favored due to its low computational effort. The high amount of 1,2-(13)C2 glucose in the optimal designs coincides with a high experimental cost, which is further enhanced when labeling is introduced in glutamine and aspartate tracers. Multi-objective optimization gives the possibility to assess experimental quality and cost at the same time and can reveal excellent compromise experiments. For example, the combination of 100% 1,2-(13)C2 glucose with 100% position one labeled glutamine and the combination of 100% 1,2-(13)C2 glucose with 100% uniformly labeled glutamine perform equally well for the carcinoma cell line, but the first mixture offers a decrease in cost of $ 120 per ml-scale cell culture experiment. We demonstrated the validity of a multi-objective linear approach to perform optimal experimental designs for the non-linear problem of (13)C-metabolic flux analysis. Tools and a workflow are provided to perform multi-objective design. The effortless calculation of the D-criterion can be exploited to perform high-throughput screening of possible (13)C-tracers, while the illustrated benefit of multi-objective design should stimulate its application within the field of (13)C-based metabolic flux analysis. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. 14 CFR Special Federal Aviation... - 5-Flightcrew Compartment Access and Door Designs

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Designs Federal Special Federal Aviation Regulation 92 Aeronautics and Space FEDERAL AVIATION... No. 92-5 Special Federal Aviation Regulation 92-5—Flightcrew Compartment Access and Door Designs 1. Applicability. This Special Federal Aviation Regulation (SFAR) applies to all operators that hold an air carrier...

  6. 14 CFR Special Federal Aviation... - 5-Flightcrew Compartment Access and Door Designs

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Designs Federal Special Federal Aviation Regulation 92 Aeronautics and Space FEDERAL AVIATION... No. 92-5 Special Federal Aviation Regulation 92-5—Flightcrew Compartment Access and Door Designs 1. Applicability. This Special Federal Aviation Regulation (SFAR) applies to all operators that hold an air carrier...

  7. 77 FR 36409 - ``Specially Designed'' Definition

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ... Regulations (ITAR). The term ``specially designed'' is used widely in the Commerce Control List (CCL) and...) controls ``[c]omponents, parts, accessories, attachments and associated equipment specifically designed or... and, in order to avoid a definitional loop, do not use ``specially designed'' as a control criterion...

  8. An experimental technique for performing 3-D LDA measurements inside whirling annular seals

    NASA Technical Reports Server (NTRS)

    Morrison, Gerald L.; Johnson, Mark C.; Deotte, Robert E., Jr.; Thames, H. Davis, III.; Wiedner, Brian G.

    1992-01-01

    During the last several years, the Fluid Mechanics Division of the Turbomachinery Laboratory at Texas A&M University has developed a rather unique facility with the experimental capability for measuring the flow field inside journal bearings, labyrinth seals, and annular seals. The facility consists of a specially designed 3-D LDA system which is capable of measuring the instantaneous velocity vector within 0.2 mm of a wall while the laser beams are aligned almost perpendicular to the wall. This capability was required to measure the flow field inside journal bearings, labyrinth seals, and annular seals. A detailed description of this facility along with some representative results obtained for a whirling annular seal are presented.

  9. Characterization and simulation of soft gamma-ray mirrors for their use with spent fuel rods at reprocessing facilities

    DOE PAGES

    Ruz, J.; Descalle, M. A.; Alameda, J. B.; ...

    2016-05-24

    The use of a grazing incidence optic to selectively reflect K-shell fluorescence emission and isotope-specific lines from special nuclear materials is a highly desirable nondestructive analysis method for use in reprocessing fuel environments. Preliminary measurements have been performed, and a simulation suite has been developed to give insight into the design of the x ray optics system as a function of the source emission, multilayer coating characteristics, and general experimental configurations. As a result, the experimental results are compared to the predictions from our simulation toolkit to illustrate the ray-tracing capability and explore the effect of modified optics in futuremore » measurement campaigns.« less

  10. An ultrahigh vacuum multipurpose specimen chamber with sample introduction system for in situ transmission electron microscopy investigations

    NASA Technical Reports Server (NTRS)

    Heinemann, K.; Poppa, H.

    1986-01-01

    A commercial transmission electron microscope (TEM), with flat-plate upper pole piece configuration of the objective lens, and top-entry specimen introduction was modified by introducing an ultrahigh vacuum (UHV) specimen chamber for in situ TEM experimentation. The pumping and design principles and special features of this UHV chamber, which makes it possible to obtain 5 x 10 to the -10th mbar pressure at the site of the specimen, while maintaining the airlock system that allows operation in the 10 to the -10th mbar range within 15 min after specimen change, are described. Design operating pressures and image quality (resolution of metal particles smaller than 1 nm in size) were achieved. Schematic drawings and design dimensions are included.

  11. Optimization of a high-pressure pore water extraction device.

    PubMed

    Cyr, Martin; Daidié, Alain

    2007-02-01

    High-pressure squeezing is a technique used for the extraction of the pore water of porous materials such as sediments, soils, rocks, and concrete. The efficiency of extraction depends on the maximum pressures on the materials. This article presents the design of a high-pressure device reaching an axial pressure of 1000 MPa which has been developed to improve the efficiency of extraction. The increase in squeezing pressure implies high stresses inside the chamber, so specialized expertise was required to design a safe, functional device that could withstand pressures significantly higher than common laboratory equipment. The design includes finite element calculations, selection of appropriate materials, and descriptive construction details for the apparatus. It also includes an experimental study of the performance of the apparatus in terms of extraction efficiency.

  12. Emotional state talk and emotion understanding: a training study with preschool children.

    PubMed

    Gavazzi, Ilaria Grazzani; Ornaghi, Veronica

    2011-11-01

    ABSTRACTThe present study investigates whether training preschool children in the active use of emotional state talk plays a significant role in bringing about greater understanding of emotion terms and improved emotion comprehension. Participants were 100 preschool children (M=52 months; SD=9·9; range: 35-70 months), randomly assigned to experimental or control conditions. They were pre- and post-tested to assess their language comprehension, metacognitive language comprehension and emotion understanding. Analyses of pre-test data did not show any significant differences between experimental and control groups. During the intervention phase, the children were read stories enriched with emotional lexicon. After listening to the stories, children in the experimental group took part in conversational language games designed to stimulate use of the selected emotional terms. In contrast, the control group children did not take part in any special linguistic activities after the story readings. Analyses revealed that the experimental group outperformed the control group in the understanding of inner state language and in the comprehension of emotion.

  13. Quality of nursing diagnoses: evaluation of an educational intervention.

    PubMed

    Florin, Jan; Ehrenberg, Anna; Ehnfors, Margareta

    2005-01-01

    To investigate the effects on the quality of nursing diagnostic statements in patient records after education in the nursing process and implementation of new forms for recording. Quasi-experimental design. Randomly selected patient records reviewed before and after intervention from one experimental unit (n = 70) and three control units (n = 70). A scale with 14 characteristics pertaining to nursing diagnoses was developed and used together with the instrument (CAT-CH-ING) for record review. Quality of nursing diagnostic statements improved in the experimental unit, whereas no improvement was found in the control units. Serious flaws in the use of the etiology component were found. CONCLUSION. Nurses must be more concerned with the accuracy and quality of the nursing diagnoses and the etiology component needs to be given special attention. Education of RNs in nursing diagnostic statements and peer review using standardized evaluation instruments can be means to further enhance RNs' documentation practice.

  14. Atrial and ventricular septal changes in ethanol vapour exposed chick embryos.

    PubMed

    Kamran, Kiran; Khan, Muhammad Yunus; Minhas, Liaqat Ali

    2015-03-01

    To study the effects of ethanol vapour exposure on development of atrial and ventricular septa of chick embryo. The experimental study was conducted at the College of Physicians and Surgeons, Islamabad, from 2006 to 2007. The experimental and control groups were further divided into three subgroups based on the day of sacrifice. The experimental group was exposed to ethanol vapours produced in a specially-designed vapour chamber and then compared with age-matched controls. There were 90 eggs in each of the two groups. The development of inter-ventricular septum completed at day 7 of development in chick embryo. Ethanol vapour exposure produced a small discontinuity at day 10 of development in a chick embryo which may be labelled as ventricular septal defect since ventricular development is completed by day 7. Interatrial septum formed till day 7 with small perforations which persisted till hatching. Ethanol vapour exposure may lead to ventricular septal defect.

  15. Immunomagnetic separation for MEMS-based biosensor of waterborne pathogens detection

    NASA Astrophysics Data System (ADS)

    Guo, Jianjiang; Zhang, Rongbiao

    2017-07-01

    Rapid isolation and detection of special pathogens present in environmental drinking water is critical for water quality monitoring. Numerical analysis and experimental investigations on immunomagnetic capture and isolation of waterborne pathogens with magnetic nanoparticles (MNPs) in microfluidic channel are performed. A finite-element COMSOL-based model is established to demonstrate the novel method of on-chip capturing pathogens using MNPs together with periodic pulse magnetic field. Simulation results determine the optimum magnetic pole current and switching frequency for magnetic separation. With the magnetic isolation experiment platform built up, as a pathogen example of Escherichia coli O157:H7, the performance of the method is experimentally verified. Both numerical and experimental results are found to agree reasonably well. Results of these investigations show that the capture efficiency of the immunomagnetic separation method is more than 92%, which could be encouraging for the design and optimization of MEMS-based biosensor of waterborne pathogen detection.

  16. Spin test of turbine rotor

    NASA Technical Reports Server (NTRS)

    Vavra, M. H.; Hammer, J. E.; Bell, L. E.

    1972-01-01

    Experimental data are presented for the tangential and radial stresses in the disks of the 36,000 horsepower, 4000 rpm turbine for the M-1 engine oxidizer turbopump. The two-stage Curtis turbine is a special light-weight design utilizing thin conical disks with hollow sheet metal blades attached by electron-beam welding techniques. The turbine was fabricated from Inconel 718, a nickel-chromium alloy. The stresses were obtained by strain-gage measurements using a slip-ring assembly to transmit the electrical signals. Measurements were made at different rotative speeds and different thermal loads. In addition to presenting test data, the report describes test equipment, design of associated hardware, test procedures, instrumentation, and tests for the selection and calibration of strain gages.

  17. 43 CFR 423.60 - How special use areas are designated.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false How special use areas are designated. 423... Use Areas § 423.60 How special use areas are designated. (a) After making a determination under paragraph (b) of this section, an authorized official may: (1) Establish special use areas within...

  18. 43 CFR 423.60 - How special use areas are designated.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false How special use areas are designated. 423... Use Areas § 423.60 How special use areas are designated. (a) After making a determination under paragraph (b) of this section, an authorized official may: (1) Establish special use areas within...

  19. Performance study of the neutron-TPC

    NASA Astrophysics Data System (ADS)

    Huang, Meng; Li, Yulan; Niu, Libo; Deng, Zhi; Cheng, Xiaolei; He, Li; Zhang, Hongyan; Fu, Jianqiang; Yan, Yangyang; Cai, Yiming; Li, Yuanjing

    2017-02-01

    Fast neutron spectrometers will play an important role in the future of the nuclear industry and nuclear physics experiments, in tasks such as fast neutron reactor monitoring, thermo-nuclear fusion plasma diagnostics, nuclear reaction cross-section measurement, and special nuclear material detection. Recently, a new fast neutron spectrometer based on a GEM (Gas Electron Multiplier amplification)-TPC (Time Projection Chamber), named the neutron-TPC, has been under development at Tsinghua University. It is designed to have a high energy resolution, high detection efficiency, easy access to the medium material, an outstanding n/γ suppression ratio, and a wide range of applications. This paper presents the design, test, and experimental study of the neutron-TPC. Based on the experimental results, the energy resolution (FWHM) of the neutron-TPC can reach 15.7%, 10.3% and 7.0% with detection efficiency higher than 10-5 for 1.2 MeV, 1.81 MeV and 2.5 MeV neutrons respectively. Supported by National Natural Science Foundation of China (11275109)

  20. A novel multiport cylinder dryer.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Choi, S. U.; Yu, W.; France, D. M.

    2001-02-01

    A multiport dryer design concept that could create breakthroughs in the drying of pulp and paper is under development. The feasibility of this novel concept was demonstrated in a proof-of-concept test. Experiments were performed in a specially designed test apparatus to investigate the condensing heat-transfer characteristics of a single channel (representative of a multiport cylinder dryer) under typical operating conditions. The experimental results showed that multiport cylinder-dryer technology provides very high heat-transfer coefficients of 15,000 W/m{sup 2}{center_dot}K (2600 Btu/h{center_dot}ft{sup 2} {sup o}F) and a highly uniform distribution of cylinder-wall temperature. These experimental results suggest that a multiport cylinder dryer canmore » increase the rate of paper drying compared with a conventional cylinder dryer. The increased dryer efficiency translates into either a reduction in the number of dryers at the same level of production or an increase in the rate of production with the same number of dryers.« less

  1. Inertia-Controlled Twinning in Ni-Mn-Ga Actuators: A Discrete Twin-Boundary Dynamics Study

    NASA Astrophysics Data System (ADS)

    Faran, Eilon; Riccardi, Leonardo; Shilo, Doron

    2017-09-01

    A discrete twin-boundary modeling approach is applied for simulating the dynamic magnetomechanical response of a Ni-Mn-Ga actuator over a wide frequency range. The model is based on experimentally measured kinetic relation of individual twin boundaries and takes into account inertial forces due to acceleration of the actuator's mass. The calculated results show good agreement with experimental measurements performed on a specially designed Ni-Mn-Ga linear spring-mass actuator. In addition, the simulation reveals several new effects that have not been considered before and can be applied to the design of improved actuators. It is identified that the demagnetization effect plays a role of an "effective spring" and results in a resonance-type response. The effects of the actuator's mass and the twin-boundary density on the resonance response and the actuator performance are explored numerically. In particular, it is shown that mass-inertia poses an inherent upper limit over the actuator's bandwidth, which is approximately constant and equals to about 200 Hz.

  2. Monolithic hybrid optics for focusing ultrashort laser pulses

    NASA Astrophysics Data System (ADS)

    Fuchs, U.

    2014-03-01

    Almost any application of ultrashort laser pulses involves focusing them in order to reach high intensities and/or small spot sizes as needed for micro-machining or Femto-LASIK. Hence, it is indispensable to be able to understand pulse front distortion caused by real world optics. Focusing causes pulse front distortion due to aberrations, dispersion and diffraction. Thus, the spatio-temporal profile of ultrashort laser is altered, which increases automatically the pulse duration and the focusing spot. Consequently, the main advantage of having ultrashort laser pulses - pulse durations way below 100 fs - can be lost in that one last step of the experimental set-up by focusing them unfavorable. Since compensating for dispersion, aberration and diffraction effects is quite complicated and not always possible, we pursue a different approach. We present a specially designed monolithic hybrid optics comprising refraction and diffraction effects for tight spatial and temporal focusing of ultrashort laser pulses. Both aims can be put into practice by having a high numerical aperture (NA = 0.35) and low internal dispersion at the same time. The focusing properties are very promising, due to a design, which provides diffraction limited focusing for 100 nm bandwidth at 780 nm center wavelength. Thus, pulses with durations as short as 10 fs can be focused without pulse front distortion. The outstanding performance of this optics is shown in theory and experimentally. Above that, such focusing optics are easily adapted to their special purpose - changing the center wavelength, achromatic bandwidth or even correcting for focusing into material is possible.

  3. 22 CFR 120.41 - Specially designed.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., integration design, layouts. Note 3 to paragraph (b)(3): Commodities in “production” that are subsequently... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Specially designed. 120.41 Section 120.41... § 120.41 Specially designed. (a) Except for commodities or software described in paragraph (b) of this...

  4. Spaceflight payload design flight experience G-408

    NASA Technical Reports Server (NTRS)

    Durgin, William W.; Looft, Fred J.; Sacco, Albert, Jr.; Thompson, Robert; Dixon, Anthony G.; Roberti, Dino; Labonte, Robert; Moschini, Larry

    1992-01-01

    Worcester Polytechnic Institute's first payload of spaceflight experiments flew aboard Columbia, STS-40, during June of 1991 and culminated eight years of work by students and faculty. The Get Away Special (GAS) payload was installed on the GAS bridge assembly at the aft end of the cargo bay behind the Spacelab Life Sciences (SLS-1) laboratory. The Experiments were turned on by astronaut signal after reaching orbit and then functioned for 72 hours. Environmental and experimental measurements were recorded on three cassette tapes which, together with zeolite crystals grown on orbit, formed the basis of subsequent analyses. The experiments were developed over a number of years by undergraduate students meeting their project requirements for graduation. The experiments included zeolite crystal growth, fluid behavior, and microgravity acceleration measurement in addition to environmental data acquisition. Preparation also included structural design, thermal design, payload integration, and experiment control. All of the experiments functioned on orbit and the payload system performed within design estimates.

  5. International Space University variable gravity research facility design

    NASA Astrophysics Data System (ADS)

    Bailey, Sheila G.; Chiaramonte, Francis P.; Davidian, Kenneth J.

    1994-03-01

    A manned mission to Mars will require long travel times between Earth and Mars. However, exposure to long-duration zero gravity is known to be harmful to the human body. Some of the harmful effects are loss of heart and lung capacity, inability to stand upright, muscular weakness, and loss of bone calcium. A variable gravity research facility (VGRF) that will be placed in low Earth orbit (LEO) was designed by students of the International Space University 1989 Summer Session held in Strasbourg, France, to provide a testbed for conducting experiments in the life and physical sciences in preparation for a mission to Mars. This design exercise was unique because it addressed all aspects concerning a large space project. This report describes the VGRF design that was developed by international participants specializing in the following areas: the politics of international cooperation; engineering, architecture; in-space physiological, materials, and life science experimentation; data communications; and business and management.

  6. The International Space University's variable gravity research facility design

    NASA Astrophysics Data System (ADS)

    Bailey, Sheila G.; Chiaramonte, Francis P.; Davidian, Kenneth J.

    1991-09-01

    A manned mission to Mars will require long travel times between Earth and Mars. However, exposure to long-duration zero gravity is known to be harmful to the human body. Some of the harmful effects are loss of heart and lung capacity, inability to stand upright, muscular weakness and loss of bone calcium. A variable gravity research facility (VGRF) that would be placed in low Earth orbit (LEO) was designed by students of the International Space University 1989 Summer Session held in Strasbourg, France, to provide a testbed for conducting experiments in the life and physical sciences in preparation for a mission to Mars. This design exercise was unique because it addressed all aspects concerning a large space project. The VGRF design was described which was developed by international participants specializing in the following areas: the politics of international cooperation, engineering, architecture, in-space physiology, material and life science experimentation, data communications, business, and management.

  7. Computer aided design of digital controller for radial active magnetic bearings

    NASA Technical Reports Server (NTRS)

    Cai, Zhong; Shen, Zupei; Zhang, Zuming; Zhao, Hongbin

    1992-01-01

    A five degree of freedom Active Magnetic Bearing (AMB) system is developed which is controlled by digital controllers. The model of the radial AMB system is linearized and the state equation is derived. Based on the state variables feedback theory, digital controllers are designed. The performance of the controllers are evaluated according to experimental results. The Computer Aided Design (CAD) method is used to design controllers for magnetic bearings. The controllers are implemented with a digital signal processing (DSP) system. The control algorithms are realized with real-time programs. It is very easy to change the controller by changing or modifying the programs. In order to identify the dynamic parameters of the controlled magnetic system, a special experiment was carried out. Also, the online Recursive Least Squares (RLS) parameter identification method is studied. It can be realized with the digital controllers. Online parameter identification is essential for the realization of an adaptive controller.

  8. The International Space University's variable gravity research facility design

    NASA Technical Reports Server (NTRS)

    Bailey, Sheila G.; Chiaramonte, Francis P.; Davidian, Kenneth J.

    1991-01-01

    A manned mission to Mars will require long travel times between Earth and Mars. However, exposure to long-duration zero gravity is known to be harmful to the human body. Some of the harmful effects are loss of heart and lung capacity, inability to stand upright, muscular weakness and loss of bone calcium. A variable gravity research facility (VGRF) that would be placed in low Earth orbit (LEO) was designed by students of the International Space University 1989 Summer Session held in Strasbourg, France, to provide a testbed for conducting experiments in the life and physical sciences in preparation for a mission to Mars. This design exercise was unique because it addressed all aspects concerning a large space project. The VGRF design was described which was developed by international participants specializing in the following areas: the politics of international cooperation, engineering, architecture, in-space physiology, material and life science experimentation, data communications, business, and management.

  9. Using factorial experimental design to evaluate the separation of plastics by froth flotation.

    PubMed

    Salerno, Davide; Jordão, Helga; La Marca, Floriana; Carvalho, M Teresa

    2018-03-01

    This paper proposes the use of factorial experimental design as a standard experimental method in the application of froth flotation to plastic separation instead of the commonly used OVAT method (manipulation of one variable at a time). Furthermore, as is common practice in minerals flotation, the parameters of the kinetic model were used as process responses rather than the recovery of plastics in the separation products. To explain and illustrate the proposed methodology, a set of 32 experimental tests was performed using mixtures of two polymers with approximately the same density, PVC and PS (with mineral charges), with particle size ranging from 2 to 4 mm. The manipulated variables were frother concentration, air flow rate and pH. A three-level full factorial design was conducted. The models establishing the relationships between the manipulated variables and their interactions with the responses (first order kinetic model parameters) were built. The Corrected Akaike Information Criterion was used to select the best fit model and an analysis of variance (ANOVA) was conducted to identify the statistically significant terms of the model. It was shown that froth flotation can be used to efficiently separate PVC from PS with mineral charges by reducing the floatability of PVC, which largely depends on the action of pH. Within the tested interval, this is the factor that most affects the flotation rate constants. The results obtained show that the pure error may be of the same magnitude as the sum of squares of the errors, suggesting that there is significant variability within the same experimental conditions. Thus, special care is needed when evaluating and generalizing the process. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Solar Pumped Solid State Lasers for Space Solar Power: Experimental Path

    NASA Technical Reports Server (NTRS)

    Fork, Richard L.; Carrington, Connie K.; Walker, Wesley W.; Cole, Spencer T.; Green, Jason J. A.; Laycock, Rustin L.

    2003-01-01

    We outline an experimentally based strategy designed to lead to solar pumped solid state laser oscillators useful for space solar power. Our method involves solar pumping a novel solid state gain element specifically designed to provide efficient conversion of sunlight in space to coherent laser light. Kilowatt and higher average power is sought from each gain element. Multiple such modular gain elements can be used to accumulate total average power of interest for power beaming in space, e.g., 100 kilowatts and more. Where desirable the high average power can also be produced as a train of pulses having high peak power (e.g., greater than 10(exp 10 watts). The modular nature of the basic gain element supports an experimental strategy in which the core technology can be validated by experiments on a single gain element. We propose to do this experimental validation both in terrestrial locations and also on a smaller scale in space. We describe a terrestrial experiment that includes diagnostics and the option of locating the laser beam path in vacuum environment. We describe a space based experiment designed to be compatible with the Japanese Experimental Module (JEM) on the International Space Station (ISS). We anticipate the gain elements will be based on low temperature (approx. 100 degrees Kelvin) operation of high thermal conductivity (k approx. 100 W/cm-K) diamond and sapphire (k approx. 4 W/cm-K). The basic gain element will be formed by sequences of thin alternating layers of diamond and Ti:sapphire with special attention given to the material interfaces. We anticipate this strategy will lead to a particularly simple, robust, and easily maintained low mass modelocked multi-element laser oscillator useful for space solar power.

  11. Analysis of the bending stiffness and adhesion effect in RF-MEMS structures

    NASA Astrophysics Data System (ADS)

    Birleanu, C.; Pustan, M.; Dudescu, C.; Merie, V.; Pintea, I.

    2017-02-01

    Microelectromechanical system (MEMS) is a special branch with a wide range of applications in sensing, switching and actuating devices. Designing the reliable MEMS for thin free-standing structures like as bridges and cantilevers requires understanding of the tribomechanical properties of the materials and structures. The effect of geometrical dimensions (cross-section dimensions and length) on mechanical and tribological behavior of free-standing MEMS structures made of electroplated gold was analyzed in this paper. Special attention was given to the dependences between stiffness and cantilever length and the dependences between bending stress and variable travel range of actuated load. The force position was moved from the beams free-end toward to the anchor. The tests were performed at room temperature (22°C) and relative humidity RH of 40% with a noise- and vibration-isolated and environment-controlled XE-70 AFM from Park Systems using the contact mode. Each measurement was repeated many times in order to improve the accuracy of the experimental results. The stiffness of a microcantilever varies if the position of the acting force is changed. The experimental results obtained were in good correlation with those obtained analytically.

  12. WISPER: Wirless Space Power Experiment

    NASA Technical Reports Server (NTRS)

    Hawkins, Joseph

    1993-01-01

    The 1993 Advanced Design Project at the University of Alaska Fairbanks was to design a spacecraft as a technology demonstration of wireless power transmission (WPT). With cost effectiveness as a design constraint, a micro-satellite in low earth orbit (LEO) was chosen for the mission. Existing and near term technologies were analyzed and selected for the project. In addition to the conceptual design of the payload, support systems, and structure, the analysis included attention to safety, environmental impact, cost, and schedule for construction and operation. Wireless power beaming is not a new concept. Experimental demonstrations and study efforts have continued since the early 1960's. With the latest progress in transmitter and receiver technology, the next natural step is to beam power from earth to space. This proposed flight demonstration will advance the science of power beaming and prove the viability of various applications of WPT in space. Two methods of power beaming will be examined during the two separate phases of the spacecraft life. The first phase will demonstrate the technology and examine the theory of microwave power transmission at a high frequency. Special aspects of the first phase will include a highly accurate attitude control system and a 14 m inflatable parabolic antenna. The second phase will investigate the utilization of high intensity laser power using modified photovoltaic arrays. Special instrumentation on the spacecraft will measure the conversion efficiency from the received microwave or laser power to direct current power.

  13. 78 FR 55629 - Special Conditions: Cirrus Design Corporation, Model SF50; Inflatable Three-Point Restraint...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ...-0781; Special Conditions No. 23-261-SC] Special Conditions: Cirrus Design Corporation, Model SF50... conditions are issued for the Cirrus Design Corporation (Cirrus), model SF50. This airplane will have novel and unusual design features associated with installation of an inflatable three-point restraint safety...

  14. 75 FR 20518 - Special Conditions: Cirrus Design Corporation Model SF50 Airplane; Full Authority Digital Engine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-20

    ...; Special Conditions No. 23-246-SC] Special Conditions: Cirrus Design Corporation Model SF50 Airplane; Full Authority Digital Engine Control (FADEC) System AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... Cirrus Design Corporation model SF50 airplane. This airplane will have a novel or unusual design feature...

  15. Design and analysis issues for economic analysis alongside clinical trials.

    PubMed

    Marshall, Deborah A; Hux, Margaret

    2009-07-01

    Clinical trials can offer a valuable and efficient opportunity to collect the health resource use and outcomes data for economic evaluation. However, economic and clinical studies differ fundamentally in the question they seek to answer. The design and analysis of trial-based cost-effectiveness studies require special consideration, which are reviewed in this article. Traditional randomized controlled trials, using an experimental design with a controlled protocol, are designed to measure safety and efficacy for product registration. Cost-effectiveness analysis seeks to measure effectiveness in the context of routine clinical practice, and requires collection of health care resources to allow estimation of cost over an equal timeframe for each treatment alternative. In assessing suitability of a trial for economic data collection, the comparator treatment and other protocol factors need to reflect current clinical practice and the trial follow-up must be sufficiently long to capture important costs and effects. The broadest available population and a measure of effectiveness reflecting important benefits for patients are preferred for economic analyses. Special analytical issues include dealing with missing and censored cost data, assessing uncertainty of the incremental cost-effectiveness ratio, and accounting for the underlying heterogeneity in patient subgroups. Careful consideration also needs to be given to data from multinational studies since practice patterns can differ across countries. Although clinical trials can be an efficient opportunity to collect data for economic evaluation, careful consideration of the suitability of the study design, and appropriate analytical methods must be applied to obtain rigorous results.

  16. On-line data display

    NASA Astrophysics Data System (ADS)

    Lang, Sherman Y. T.; Brooks, Martin; Gauthier, Marc; Wein, Marceli

    1993-05-01

    A data display system for embedded realtime systems has been developed for use as an operator's user interface and debugging tool. The motivation for development of the On-Line Data Display (ODD) have come from several sources. In particular the design reflects the needs of researchers developing an experimental mobile robot within our laboratory. A proliferation of specialized user interfaces revealed a need for a flexible communications and graphical data display system. At the same time the system had to be readily extensible for arbitrary graphical display formats which would be required for data visualization needs of the researchers. The system defines a communication protocol transmitting 'datagrams' between tasks executing on the realtime system and virtual devices displaying the data in a meaningful way on a graphical workstation. The communication protocol multiplexes logical channels on a single data stream. The current implementation consists of a server for the Harmony realtime operating system and an application written for the Macintosh computer. Flexibility requirements resulted in a highly modular server design, and a layered modular object- oriented design for the Macintosh part of the system. Users assign data types to specific channels at run time. Then devices are instantiated by the user and connected to channels to receive datagrams. The current suite of device types do not provide enough functionality for most users' specialized needs. Instead the system design allows the creation of new device types with modest programming effort. The protocol, design and use of the system are discussed.

  17. Intention, Principle, Outputs and Aims of the Experimental Pavilion Research of Building Envelopes Including Windows for Wooden Buildings

    NASA Astrophysics Data System (ADS)

    Štaffenová, Daniela; Rybárik, Ján; Jakubčík, Miroslav

    2017-06-01

    The aim of experimental research in the area of exterior walls and windows suitable for wooden buildings was to build special pavilion laboratories. These laboratories are ideally isolated from the surrounding environment, airtight and controlled by the constant internal climate. The principle of experimental research is measuring and recording of required physical parameters (e.g. temperature or relative humidity). This is done in layers of experimental fragment sections in the direction from exterior to interior, as well as in critical places by stable interior and real exterior climatic conditions. The outputs are evaluations of experimental structures behaviour during the specified time period, possibly during the whole year by stable interior and real exterior boundary conditions. The main aim of this experimental research is processing of long-term measurements of experimental structures and the subsequent analysis. The next part of the research consists of collecting measurements obtained with assistance of the experimental detached weather station, analysis, evaluation for later setting up of reference data set for the research locality, from the point of view of its comparison to the data sets from Slovak Hydrometeorological Institute (SHMU) and to localities with similar climate conditions. Later on, the data sets could lead to recommendations for design of wooden buildings.

  18. 50 CFR 17.86 - Special rules-plants. [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 2 2014-10-01 2014-10-01 false Special rules-plants. [Reserved] 17.86... WILDLIFE AND PLANTS (CONTINUED) ENDANGERED AND THREATENED WILDLIFE AND PLANTS Experimental Populations § 17.86 Special rules—plants. [Reserved] ...

  19. 50 CFR 17.86 - Special rules-plants. [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 2 2011-10-01 2011-10-01 false Special rules-plants. [Reserved] 17.86... WILDLIFE AND PLANTS (CONTINUED) ENDANGERED AND THREATENED WILDLIFE AND PLANTS Experimental Populations § 17.86 Special rules—plants. [Reserved] ...

  20. 50 CFR 17.86 - Special rules-plants. [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 2 2010-10-01 2010-10-01 false Special rules-plants. [Reserved] 17.86... WILDLIFE AND PLANTS (CONTINUED) ENDANGERED AND THREATENED WILDLIFE AND PLANTS Experimental Populations § 17.86 Special rules—plants. [Reserved] ...

  1. Nuclear shieldings with the SSB-D functional.

    PubMed

    Armangué, Lluís; Solà, Miquel; Swart, Marcel

    2011-02-24

    The recently reported SSB-D functional [J. Chem. Phys. 2009, 131, 094103] is used to check the performance for obtaining nuclear magnetic resonance (NMR) shielding constants. Four different databases were studied, which contain a diversity of molecules and nuclear shielding constants. The SSB-D functional is compared with its "parent" functionals (PBE, OPBE), the KT2 functional that was designed specially for NMR applications and the coupled cluster CCSD(T) method. The best performance for the experimentally most-used elements ((1)H, (13)C) is obtained for the SSB-D and KT2 functionals.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Repins, Ingrid; Jordan, Dirk; Bosco, Nick

    The proposed new IEC standard will address the test temperature requirements in IEC 61215 (module design), IEC 61730 (module safety), IEC 62790 (junction box safety) and IEC 62852 (connectors), and will provide guidelines to modify temperature limits in four existing standards to better describe module performance in hotter climates. This workshop includes four presentations: Special Testing for Modules Deployed in Hot Use Environments - Are We Doing This in a Low-Cost Way?, Experimental Evidence, Why the highest temperatures are the most stressful to PV modules during thermal cycling, and Safety Aspects for Modules Deployed in Hot Use Environments.

  3. Sequence design and software environment for real-time navigation of a wireless ferromagnetic device using MRI system and single echo 3D tracking.

    PubMed

    Chanu, A; Aboussouan, E; Tamaz, S; Martel, S

    2006-01-01

    Software architecture for the navigation of a ferromagnetic untethered device in a 1D and 2D phantom environment is briefly described. Navigation is achieved using the real-time capabilities of a Siemens 1.5 T Avanto MRI system coupled with a dedicated software environment and a specially developed 3D tracking pulse sequence. Real-time control of the magnetic core is executed through the implementation of a simple PID controller. 1D and 2D experimental results are presented.

  4. Confocal Raman Microspectroscopy: The Measurement of VX Depth Profiles in Hairless Guinea Pig Skin and the Evaluation of RSDL

    DTIC Science & Technology

    2015-02-01

    Defense, or the U.S. Government. The experimental protocol was approved by the Animal Care and Use Committee at the United States Army Medical Research...Laboratory Animals and the Animal Welfare Act of 1966 (P.L. 89-544), as amended. The use of trade names does not constitute an official endorsement or...neat VX (0.3 µl, 13-14 x LD50), using a specially designed template that allowed repeated Raman measurements on the same skin location. Animals were

  5. Experiment Definition Using the Space Laboratory, Long Duration Exposure Facility, and Space Transportation System Shuttle

    NASA Technical Reports Server (NTRS)

    Sheppard, Albert P.; Wood, Joan M.

    1976-01-01

    Candidate experiments designed for the space shuttle transportation system and the long duration exposure facility are summarized. The data format covers: experiment title, Experimenter, technical abstract, benefits/justification, technical discussion of experiment approach and objectives, related work and experience, experiment facts space properties used, environmental constraints, shielding requirements, if any, physical description, and sketch of major elements. Information was also included on experiment hardware, research required to develop experiment, special requirements, cost estimate, safety considerations, and interactions with spacecraft and other experiments.

  6. Reconfigurable Flight Control Using Nonlinear Dynamic Inversion with a Special Accelerometer Implementation

    NASA Technical Reports Server (NTRS)

    Bacon, Barton J.; Ostroff, Aaron J.

    2000-01-01

    This paper presents an approach to on-line control design for aircraft that have suffered either actuator failure, missing effector surfaces, surface damage, or any combination. The approach is based on a modified version of nonlinear dynamic inversion. The approach does not require a model of the baseline vehicle (effectors at zero deflection), but does require feedback of accelerations and effector positions. Implementation issues are addressed and the method is demonstrated on an advanced tailless aircraft. An experimental simulation analysis tool is used to directly evaluate the nonlinear system's stability robustness.

  7. The Special Education Teacher as an Instructional Designer. Rational, Content, and Strategy for an Innovative Individualized Course on Instructional Design in Special Education. Working Paper 9.14.

    ERIC Educational Resources Information Center

    Thiagarajan, Sivasailam

    Provided are the rationale, content and strategy for an introductory course in instructional design for special education teachers. The teacher's need for varied competencies in instructional design, management and interaction are discussed. It is recommended that teacher training include development of such design skills as task analysis, learner…

  8. The high velocity impact loading on symmetrical and woven hybrid composite laminates

    NASA Astrophysics Data System (ADS)

    Jin, Martin; Richardson, Mel; Zhang, Zhong Yi

    2007-07-01

    Space structures use fibre composite materials, due to their lightweight. This paper examines the impact response of symmetrical and hybrid composite laminates. Special attention is given to the stacking sequences used. The experimental study of structures has always provided a major contribution to our understanding. Even with the formidable growth in the use and capacity of computing power the need for experimental measurement is as compelling as ever. The design of hybrid composite structures is complicated by the number of design variables and the interaction of the constituents is the composite system. Since it is desirable to experimentally test the design and it is not practical to test a full scale model, the structural/material similitude concept is used to create a small scale model with a similar structural response. In the current study, experimental investigations were carried out to determine the response of four different combinations of hybrid laminates to low-velocity impact loading using an instrumented impact testing machine. Hybrid laminates were fabricated with twill weave carbon fabric and plain weave S2-glass fabric using vacuum assisted resin molding process with SC-15 epoxy resin system. Response of carbon/epoxy and glass/epoxy laminates was also investigated to compare with that of hybrid samples. Square laminates of size 100 mm and nominal thickness of 3 mm were subjected to low-velocity impact loading at four energy levels of 10, 20, 30 and 40 J. Results of the study indicate that there is considerable improvement in the load carrying capability of hybrid composites as compared to carbon/epoxy laminates with slight reduction in stiffness.

  9. 7 CFR 868.316 - Special grade designation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FOR CERTAIN AGRICULTURAL COMMODITIES United States Standards for Milled Rice Special Grades, Special... designation for coated, granulated brewers, parboiled, undermilled, glutinous, or aromatic milled rice shall...

  10. 7 CFR 868.316 - Special grade designation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... FOR CERTAIN AGRICULTURAL COMMODITIES United States Standards for Milled Rice Special Grades, Special... designation for coated, granulated brewers, parboiled, undermilled, glutinous, or aromatic milled rice shall...

  11. Discrete event simulation tool for analysis of qualitative models of continuous processing systems

    NASA Technical Reports Server (NTRS)

    Malin, Jane T. (Inventor); Basham, Bryan D. (Inventor); Harris, Richard A. (Inventor)

    1990-01-01

    An artificial intelligence design and qualitative modeling tool is disclosed for creating computer models and simulating continuous activities, functions, and/or behavior using developed discrete event techniques. Conveniently, the tool is organized in four modules: library design module, model construction module, simulation module, and experimentation and analysis. The library design module supports the building of library knowledge including component classes and elements pertinent to a particular domain of continuous activities, functions, and behavior being modeled. The continuous behavior is defined discretely with respect to invocation statements, effect statements, and time delays. The functionality of the components is defined in terms of variable cluster instances, independent processes, and modes, further defined in terms of mode transition processes and mode dependent processes. Model construction utilizes the hierarchy of libraries and connects them with appropriate relations. The simulation executes a specialized initialization routine and executes events in a manner that includes selective inherency of characteristics through a time and event schema until the event queue in the simulator is emptied. The experimentation and analysis module supports analysis through the generation of appropriate log files and graphics developments and includes the ability of log file comparisons.

  12. Strain measurement of objects subjected to aerodynamic heating using digital image correlation: experimental design and preliminary results.

    PubMed

    Pan, Bing; Jiang, Tianyun; Wu, Dafang

    2014-11-01

    In thermomechanical testing of hypersonic materials and structures, direct observation and quantitative strain measurement of the front surface of a test specimen directly exposed to severe aerodynamic heating has been considered as a very challenging task. In this work, a novel quartz infrared heating device with an observation window is designed to reproduce the transient thermal environment experienced by hypersonic vehicles. The specially designed experimental system allows the capture of test article's surface images at various temperatures using an optical system outfitted with a bandpass filter. The captured images are post-processed by digital image correlation to extract full-field thermal deformation. To verify the viability and accuracy of the established system, thermal strains of a chromiumnickel austenite stainless steel sample heated from room temperature up to 600 °C were determined. The preliminary results indicate that the air disturbance between the camera and the specimen due to heat haze induces apparent distortions in the recorded images and large errors in the measured strains, but the average values of the measured strains are accurate enough. Limitations and further improvements of the proposed technique are discussed.

  13. Experimental design and analysis of JND test on coded image/video

    NASA Astrophysics Data System (ADS)

    Lin, Joe Yuchieh; Jin, Lina; Hu, Sudeng; Katsavounidis, Ioannis; Li, Zhi; Aaron, Anne; Kuo, C.-C. Jay

    2015-09-01

    The visual Just-Noticeable-Difference (JND) metric is characterized by the detectable minimum amount of two visual stimuli. Conducting the subjective JND test is a labor-intensive task. In this work, we present a novel interactive method in performing the visual JND test on compressed image/video. JND has been used to enhance perceptual visual quality in the context of image/video compression. Given a set of coding parameters, a JND test is designed to determine the distinguishable quality level against a reference image/video, which is called the anchor. The JND metric can be used to save coding bitrates by exploiting the special characteristics of the human visual system. The proposed JND test is conducted using a binary-forced choice, which is often adopted to discriminate the difference in perception in a psychophysical experiment. The assessors are asked to compare coded image/video pairs and determine whether they are of the same quality or not. A bisection procedure is designed to find the JND locations so as to reduce the required number of comparisons over a wide range of bitrates. We will demonstrate the efficiency of the proposed JND test, report experimental results on the image and video JND tests.

  14. 75 FR 2434 - Special Conditions: Boeing Model 747-8/-8F Series Airplanes; Design Roll Maneuver Requirement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-15

    ... have novel or unusual design features when compared to the state of technology envisioned in the... standards. Additional special conditions will be issued for other novel or unusual design features of the... 747-8/-8F because of a novel or unusual design feature, special conditions are prescribed under the...

  15. Efficiency of operation of wind turbine rotors optimized by the Glauert and Betz methods

    NASA Astrophysics Data System (ADS)

    Okulov, V. L.; Mikkelsen, R.; Litvinov, I. V.; Naumov, I. V.

    2015-11-01

    The models of two types of rotors with blades constructed using different optimization methods are compared experimentally. In the first case, the Glauert optimization by the pulsed method is used, which is applied independently for each individual blade cross section. This method remains the main approach in designing rotors of various duties. The construction of the other rotor is based on the Betz idea about optimization of rotors by determining a special distribution of circulation over the blade, which ensures the helical structure of the wake behind the rotor. It is established for the first time as a result of direct experimental comparison that the rotor constructed using the Betz method makes it possible to extract more kinetic energy from the homogeneous incoming flow.

  16. Experimental investigation of the wake behind a model of wind turbine in a water flume

    NASA Astrophysics Data System (ADS)

    Okulov, V. L.; Naumov, I. N.; Kabardin, I.; Mikkelsen, R.; Sørensen, J. N.

    2014-12-01

    The flow behind the model of wind turbine rotor is investigated experimentally in a water flume using Particle Image Velocimetry. The study carried out involves rotors of three bladed wind turbine designed using Glauert's optimization. The transitional regime, generally characterized as in between the regime governed by stable organized vortical structures and the turbulent wake, develops from disturbances of the tip and root vorticies through vortex paring and further complex behaviour towards the fully turbulent wake. Our PIV measurements pay special attention to the onset of the instabilities. The near wake characteristics (development of expansion, tip vortex position, deficit velocity and rotation in the wake) have been measured for different tip speed ratio to compare with main assumptions and conclusions of various rotor theories.

  17. Study report on interfacing major physiological subsystem models: An approach for developing a whole-body algorithm

    NASA Technical Reports Server (NTRS)

    Fitzjerrell, D. G.; Grounds, D. J.; Leonard, J. I.

    1975-01-01

    Using a whole body algorithm simulation model, a wide variety and large number of stresses as well as different stress levels were simulated including environmental disturbances, metabolic changes, and special experimental situations. Simulation of short term stresses resulted in simultaneous and integrated responses from the cardiovascular, respiratory, and thermoregulatory subsystems and the accuracy of a large number of responding variables was verified. The capability of simulating significantly longer responses was demonstrated by validating a four week bed rest study. In this case, the long term subsystem model was found to reproduce many experimentally observed changes in circulatory dynamics, body fluid-electrolyte regulation, and renal function. The value of systems analysis and the selected design approach for developing a whole body algorithm was demonstrated.

  18. Combined Experimental and Numerical Simulations of Thermal Barrier Coated Turbine Blades Erosion

    NASA Technical Reports Server (NTRS)

    Hamed, Awate; Tabakoff, Widen; Swar, Rohan; Shin, Dongyun; Woggon, Nthanial; Miller, Robert

    2013-01-01

    A combined experimental and computational study was conducted to investigate the erosion of thermal barrier coated (TBC) blade surfaces by alumina particles ingestion in a single stage turbine. In the experimental investigation, tests of particle surface interactions were performed in specially designed tunnels to determine the erosion rates and particle restitution characteristics under different impact conditions. The experimental results show that the erosion rates increase with increased impingement angle, impact velocity and temperature. In the computational simulations, an Euler-Lagrangian two stage approach is used in obtaining numerical solutions to the three-dimensional compressible Reynolds Averaged Navier-Stokes equations and the particles equations of motion in each blade passage reference frame. User defined functions (UDF) were developed to represent experimentally-based correlations for particle surface interaction models which were employed in the three-dimensional particle trajectory simulations to determine the particle rebound characteristics after each surface impact. The experimentally based erosion UDF model was used to predict the TBC erosion rates on the turbine blade surfaces based on the computed statistical data of the particles impact locations, velocities and angles relative to the blade surface. Computational results are presented for the predicted TBC blade erosion in a single stage commercial APU turbine, for a NASA designed automotive turbine, and for the NASA turbine scaled for modern rotorcraft operating conditions. The erosion patterns in the turbines are discussed for uniform particle ingestion and for particle ingestion concentrated in the inner and outer 5 percent of the stator blade span representing the flow cooling the combustor liner.

  19. 7 CFR 868.213 - Special grade designation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FOR CERTAIN AGRICULTURAL COMMODITIES United States Standards for Rough Rice Special Grades, Special... designation for infested, parboiled, smutty, glutinous, or aromatic rough rice shall include, following the...

  20. 7 CFR 868.213 - Special grade designation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... FOR CERTAIN AGRICULTURAL COMMODITIES United States Standards for Rough Rice Special Grades, Special... designation for infested, parboiled, smutty, glutinous, or aromatic rough rice shall include, following the...

  1. Experimental verification of PSM polarimetry: monitoring polarization at 193nm high-NA with phase shift masks

    NASA Astrophysics Data System (ADS)

    McIntyre, Gregory; Neureuther, Andrew; Slonaker, Steve; Vellanki, Venu; Reynolds, Patrick

    2006-03-01

    The initial experimental verification of a polarization monitoring technique is presented. A series of phase shifting mask patterns produce polarization dependent signals in photoresist and are capable of monitoring the Stokes parameters of any arbitrary illumination scheme. Experiments on two test reticles have been conducted. The first reticle consisted of a series of radial phase gratings (RPG) and employed special apertures to select particular illumination angles. Measurement sensitivities of about 0.3 percent of the clear field per percent change in polarization state were observed. The second test reticle employed the more sensitive proximity effect polarization analyzers (PEPA), a more robust experimental setup, and a backside pinhole layer for illumination angle selection and to enable characterization of the full illuminator. Despite an initial complication with the backside pinhole alignment, the results correlate with theory. Theory suggests that, once the pinhole alignment is corrected in the near future, the second reticle should achieve a measurement sensitivity of about 1 percent of the clear field per percent change in polarization state. This corresponds to a measurement of the Stokes parameters after test mask calibration, to within about 0.02 to 0.03. Various potential improvements to the design, fabrication of the mask, and experimental setup are discussed. Additionally, to decrease measurement time, a design modification and double exposure technique is proposed to enable electrical detection of the measurement signal.

  2. Benchmark Calibration Tests Completed for Stirling Convertor Heater Head Life Assessment

    NASA Technical Reports Server (NTRS)

    Krause, David L.; Halford, Gary R.; Bowman, Randy R.

    2005-01-01

    A major phase of benchmark testing has been completed at the NASA Glenn Research Center (http://www.nasa.gov/glenn/), where a critical component of the Stirling Radioisotope Generator (SRG) is undergoing extensive experimentation to aid the development of an analytical life-prediction methodology. Two special-purpose test rigs subjected SRG heater-head pressure-vessel test articles to accelerated creep conditions, using the standard design temperatures to stay within the wall material s operating creep-response regime, but increasing wall stresses up to 7 times over the design point. This resulted in well-controlled "ballooning" of the heater-head hot end. The test plan was developed to provide critical input to analytical parameters in a reasonable period of time.

  3. Structured FBG filters for 10-Gb/s DPSK signal demodulation in single ended applications

    NASA Astrophysics Data System (ADS)

    Marazzi, L.; Boffi, P.; Parolari, P.; Martinelli, M.; Gatti, D.; Coluccelli, N.; Longhi, S.

    2011-05-01

    Differential phase-shift keying (DPSK) demodulations operated by a structured fiber Bragg grating (FBG) filter and by a Mach-Zehnder delay interferometer (MZDI) in a single-ended configuration are compared. Experimental measurements at 10 Gb/s demonstrate that a specially designed FBG outperforms an integrated-optic MZDI of ˜4 dB and ˜3.5 dB in back-to-back and after 25-km propagation, respectively. Both demodulators show low polarization sensitivity and signal frequency detuning dependence, but only MZDI operating point requires a thermal control. FBG filter proves an interesting solution for DPSK demodulation in low-cost applications and, moreover, can be designed to match colorless requirements of wave division multiplexed passive optical network (WDM-PON) applications.

  4. Classroom evaluation of the Arlyn Arm robotic workstation.

    PubMed

    Eberhardt, S P; Osborne, J; Rahman, T

    2000-01-01

    High school and junior high school students with neuromuscular weakness and other disorders of the arms evaluated a recently commercialized robotic workstation, the Arlyn Arm, to carry out art projects and science experiments. These tasks were designed for independent execution with the workstation using standard or custom-designed tools. Each task was divided into subtasks, and the execution time of each subtask was determined as a measure of efficiency. Special attention was given to the causes of required experimenter intervention. While subjects easily accomplished some subtasks, others required considerable intervention. Most of these interventions could be avoided by further customizing accessories. It is concluded that the Arlyn Arm workstation could be of considerable benefit in a classroom setting to persons with severe neuromuscular disorders.

  5. Development of a special-purpose test surface guided by uncertainty analysis - Introduction of a new uncertainty analysis step

    NASA Technical Reports Server (NTRS)

    Wang, T.; Simon, T. W.

    1988-01-01

    Development of a recent experimental program to investigate the effects of streamwise curvature on boundary layer transition required making a bendable, heated and instrumented test wall, a rather nonconventional surface. The present paper describes this surface, the design choices made in its development and how uncertainty analysis was used, beginning early in the test program, to make such design choices. Published uncertainty analysis techniques were found to be of great value; but, it became clear that another step, one herein called the pre-test analysis, would aid the program development. Finally, it is shown how the uncertainty analysis was used to determine whether the test surface was qualified for service.

  6. IOTA (Integrable Optics Test Accelerator): facility and experimental beam physics program

    NASA Astrophysics Data System (ADS)

    Antipov, S.; Broemmelsiek, D.; Bruhwiler, D.; Edstrom, D.; Harms, E.; Lebedev, V.; Leibfritz, J.; Nagaitsev, S.; Park, C. S.; Piekarz, H.; Piot, P.; Prebys, E.; Romanov, A.; Ruan, J.; Sen, T.; Stancari, G.; Thangaraj, C.; Thurman-Keup, R.; Valishev, A.; Shiltsev, V.

    2017-03-01

    The Integrable Optics Test Accelerator (IOTA) is a storage ring for advanced beam physics research currently being built and commissioned at Fermilab. It will operate with protons and electrons using injectors with momenta of 70 and 150 MeV/c, respectively. The research program includes the study of nonlinear focusing integrable optical beam lattices based on special magnets and electron lenses, beam dynamics of space-charge effects and their compensation, optical stochastic cooling, and several other experiments. In this article, we present the design and main parameters of the facility, outline progress to date and provide the timeline of the construction, commissioning and research. The physical principles, design, and hardware implementation plans for the major IOTA experiments are also discussed.

  7. Logarithm conformal mapping brings the cloaking effect

    PubMed Central

    Xu, Lin; Chen, Huanyang

    2014-01-01

    Over the past years, invisibility cloaks have been extensively discussed since transformation optics emerges. Generally, the electromagnetic parameters of invisibility cloaks are complicated tensors, yet difficult to realize. As a special method of transformation optics, conformal mapping helps us design invisibility cloak with isotropic materials of a refractive index distribution. However, for all proposed isotropic cloaks, the refractive index range is at such a breadth that challenges current experimental fabrication. In this work, we propose two new kinds of logarithm conformal mappings for invisible device designs. For one of the mappings, the refractive index distribution of conformal cloak varies from 0 to 9.839, which is more feasible for future implementation. Numerical simulations by using finite element method are performed to confirm the theoretical analysis. PMID:25359138

  8. 29 CFR 1919.32 - Specially designed blocks and components.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Specially designed blocks and components. 1919.32 Section 1919.32 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION... Treatment; Competent Persons § 1919.32 Specially designed blocks and components. (a) Blocks and connecting...

  9. 78 FR 40921 - Amendment to the International Traffic in Arms Regulations: Continued Implementation of Export...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-08

    ... specially designed parts, components, accessories, and attachments therefor (a) in production, (b... production, testing and inspection equipment, and tooling, specially designed for plants or facilities..., a definition for specially designed, and responses to public comments and changes to other sections...

  10. Bio-inspired piezoelectric linear motor driven by a single-phase harmonic wave with an asymmetric stator.

    PubMed

    Pan, Qiaosheng; Miao, Enming; Wu, Bingxuan; Chen, Weikang; Lei, Xiujun; He, Liangguo

    2017-07-01

    A novel, bio-inspired, single-phase driven piezoelectric linear motor (PLM) using an asymmetric stator was designed, fabricated, and tested to avoid mode degeneracy and to simplify the drive mechanism of a piezoelectric motor. A piezoelectric transducer composed of two piezoelectric stacks and a displacement amplifier was used as the driving element of the PLM. Two simple and specially designed claws performed elliptical motion. A numerical simulation was performed to design the stator and determine the feasibility of the design mechanism of the PLM. Moreover, an experimental setup was built to validate the working principles, as well as to evaluate the performance, of the PLM. The prototype motor outputs a no-load speed of 233.7 mm/s at a voltage of 180 V p-p and a maximum thrust force of 2.3 N under a preload of 10 N. This study verified the feasibility of the proposed design and provided a method to simplify the driving harmonic signal and structure of PLMs.

  11. 78 FR 67291 - Special Conditions: Bombardier Inc., Models BD-500-1A10 and BD-500-1A11 Series Airplanes; Design...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ... have a novel or unusual design feature associated with an electronic flight control system that... because of a novel or unusual design feature, special conditions are prescribed under the provisions of... same or similar novel or unusual design feature, the special conditions would also apply to the other...

  12. Esthetic Evaluation of Anterior Single-Tooth Implants with Different Abutment Designs-Patients' Satisfaction Compared to Dentists' Observations.

    PubMed

    Patil, Ratnadeep; Gresnigt, Marco M M; Mahesh, Kavita; Dilbaghi, Anjali; Cune, Marco S

    2017-07-01

    To correlate patients' satisfaction and dentists' observations regarding two abutment designs used for single crowns in the esthetic zone: a divergent one (control) and a curved one (experimental), with special emphasis on muco-gingival esthetics. Twenty-six patients with nonadjacent missing teeth in the esthetic zone were enrolled in a randomized clinical trial (within-subject comparison). Two implants placed in each were restored using abutments of different geometry. Patients' appreciation was assessed on a visual analog scale (VAS) by recording answers to three questions, and dentists' appreciation was determined by means of the Pink Esthetic Score (PES) at T0 (crown cementation, baseline) and at T12 (1 year post-cementation). ANOVA with post hoc analysis was used to identify differences between groups and at different moments in time. Pearson correlations were calculated between all variables, both at T0 and at T12. No statistically significant differences were found at any time between the control and experimental abutment design, either for the PES or for the VAS score. PES slightly improved after 1 year, as did the VAS rating related to functioning with the implant-crown compared to the natural teeth. All PES and VAS scores demonstrated highly significant correlation. Both patient satisfaction and professional appreciation of muco-gingival conditions after single implant treatment in the esthetic zone were high; however, the curved, experimental abutment design performed no better than the conventional, divergent type. Curved abutment design does not significantly impact crown or gingival esthetics as assessed by PES and VAS scored by dentists and patients, respectively. © 2016 by the American College of Prosthodontists.

  13. 78 FR 31431 - Export Administration Regulations (EAR): Control of Spacecraft Systems and Related Items the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    .... Paragraph 9A515.b would control ground control systems and training simulators ``specially designed'' for.... Paragraph .d would control certain radiation hardened microelectronic circuits that are ``specially designed... .a would control test, inspection, and production ``equipment'' ``specially designed'' for the...

  14. Overview of the Systems Special Investigation Group investigation

    NASA Technical Reports Server (NTRS)

    Mason, James B.; Dursch, Harry; Edelman, Joel

    1993-01-01

    The Long Duration Exposure Facility (LDEF) carried a remarkable variety of electrical, mechanical, thermal, and optical systems, subsystems, and components. Nineteen of the fifty-seven experiments flown on LDEF contained functional systems that were active on-orbit. Almost all of the other experiments possessed at least a few specific components of interest to the Systems Special Investigation Group (Systems SIG), such as adhesives, seals, fasteners, optical components, and thermal blankets. Almost all top level functional testing of the active LDEF and experiment systems has been completed. Failure analysis of both LDEF hardware and individual experiments that failed to perform as designed has also been completed. Testing of system components and experimenter hardware of interest to the Systems SIG is ongoing. All available testing and analysis results were collected and integrated by the Systems SIG. An overview of our findings is provided. An LDEF Optical Experiment Database containing information for all 29 optical related experiments is also discussed.

  15. Self-folding origami at any energy scale

    NASA Astrophysics Data System (ADS)

    Pinson, Matthew B.; Stern, Menachem; Carruthers Ferrero, Alexandra; Witten, Thomas A.; Chen, Elizabeth; Murugan, Arvind

    2017-05-01

    Programmable stiff sheets with a single low-energy folding motion have been sought in fields ranging from the ancient art of origami to modern meta-materials research. Despite such attention, only two extreme classes of crease patterns are usually studied; special Miura-Ori-based zero-energy patterns, in which crease folding requires no sheet bending, and random patterns with high-energy folding, in which the sheet bends as much as creases fold. We present a physical approach that allows systematic exploration of the entire space of crease patterns as a function of the folding energy. Consequently, we uncover statistical results in origami, finding the entropy of crease patterns of given folding energy. Notably, we identify three classes of Mountain-Valley choices that have widely varying `typical' folding energies. Our work opens up a wealth of experimentally relevant self-folding origami designs not reliant on Miura-Ori, the Kawasaki condition or any special symmetry in space.

  16. Development and analysis of the Software Implemented Fault-Tolerance (SIFT) computer

    NASA Technical Reports Server (NTRS)

    Goldberg, J.; Kautz, W. H.; Melliar-Smith, P. M.; Green, M. W.; Levitt, K. N.; Schwartz, R. L.; Weinstock, C. B.

    1984-01-01

    SIFT (Software Implemented Fault Tolerance) is an experimental, fault-tolerant computer system designed to meet the extreme reliability requirements for safety-critical functions in advanced aircraft. Errors are masked by performing a majority voting operation over the results of identical computations, and faulty processors are removed from service by reassigning computations to the nonfaulty processors. This scheme has been implemented in a special architecture using a set of standard Bendix BDX930 processors, augmented by a special asynchronous-broadcast communication interface that provides direct, processor to processor communication among all processors. Fault isolation is accomplished in hardware; all other fault-tolerance functions, together with scheduling and synchronization are implemented exclusively by executive system software. The system reliability is predicted by a Markov model. Mathematical consistency of the system software with respect to the reliability model has been partially verified, using recently developed tools for machine-aided proof of program correctness.

  17. Knowledge engineering tools for reasoning with scientific observations and interpretations: a neural connectivity use case.

    PubMed

    Russ, Thomas A; Ramakrishnan, Cartic; Hovy, Eduard H; Bota, Mihail; Burns, Gully A P C

    2011-08-22

    We address the goal of curating observations from published experiments in a generalizable form; reasoning over these observations to generate interpretations and then querying this interpreted knowledge to supply the supporting evidence. We present web-application software as part of the 'BioScholar' project (R01-GM083871) that fully instantiates this process for a well-defined domain: using tract-tracing experiments to study the neural connectivity of the rat brain. The main contribution of this work is to provide the first instantiation of a knowledge representation for experimental observations called 'Knowledge Engineering from Experimental Design' (KEfED) based on experimental variables and their interdependencies. The software has three parts: (a) the KEfED model editor - a design editor for creating KEfED models by drawing a flow diagram of an experimental protocol; (b) the KEfED data interface - a spreadsheet-like tool that permits users to enter experimental data pertaining to a specific model; (c) a 'neural connection matrix' interface that presents neural connectivity as a table of ordinal connection strengths representing the interpretations of tract-tracing data. This tool also allows the user to view experimental evidence pertaining to a specific connection. BioScholar is built in Flex 3.5. It uses Persevere (a noSQL database) as a flexible data store and PowerLoom® (a mature First Order Logic reasoning system) to execute queries using spatial reasoning over the BAMS neuroanatomical ontology. We first introduce the KEfED approach as a general approach and describe its possible role as a way of introducing structured reasoning into models of argumentation within new models of scientific publication. We then describe the design and implementation of our example application: the BioScholar software. This is presented as a possible biocuration interface and supplementary reasoning toolkit for a larger, more specialized bioinformatics system: the Brain Architecture Management System (BAMS).

  18. Knowledge engineering tools for reasoning with scientific observations and interpretations: a neural connectivity use case

    PubMed Central

    2011-01-01

    Background We address the goal of curating observations from published experiments in a generalizable form; reasoning over these observations to generate interpretations and then querying this interpreted knowledge to supply the supporting evidence. We present web-application software as part of the 'BioScholar' project (R01-GM083871) that fully instantiates this process for a well-defined domain: using tract-tracing experiments to study the neural connectivity of the rat brain. Results The main contribution of this work is to provide the first instantiation of a knowledge representation for experimental observations called 'Knowledge Engineering from Experimental Design' (KEfED) based on experimental variables and their interdependencies. The software has three parts: (a) the KEfED model editor - a design editor for creating KEfED models by drawing a flow diagram of an experimental protocol; (b) the KEfED data interface - a spreadsheet-like tool that permits users to enter experimental data pertaining to a specific model; (c) a 'neural connection matrix' interface that presents neural connectivity as a table of ordinal connection strengths representing the interpretations of tract-tracing data. This tool also allows the user to view experimental evidence pertaining to a specific connection. BioScholar is built in Flex 3.5. It uses Persevere (a noSQL database) as a flexible data store and PowerLoom® (a mature First Order Logic reasoning system) to execute queries using spatial reasoning over the BAMS neuroanatomical ontology. Conclusions We first introduce the KEfED approach as a general approach and describe its possible role as a way of introducing structured reasoning into models of argumentation within new models of scientific publication. We then describe the design and implementation of our example application: the BioScholar software. This is presented as a possible biocuration interface and supplementary reasoning toolkit for a larger, more specialized bioinformatics system: the Brain Architecture Management System (BAMS). PMID:21859449

  19. The MaPLE device of Saha Institute of Nuclear Physics: construction and its plasma aspects.

    PubMed

    Pal, Rabindranath; Biswas, Subir; Basu, Subhasis; Chattopadhyay, Monobir; Basu, Debjyoti; Chaudhuri, Manis; Chowdhuri, Manis

    2010-07-01

    The Magnetized Plasma Linear Experimental (MaPLE) device is a low cost laboratory plasma device at Saha Institute of Nuclear Physics fabricated in-house with the primary aim of studying basic plasma physics phenomena such as plasma instabilities, wave propagation, and their nonlinear behavior in magnetized plasma regime in a controlled manner. The machine is specially designed to be a versatile laboratory device that can provide a number of magnetic and electric scenario to facilitate such studies. A total of 36 number of 20-turn magnet coils, designed such as to allow easy handling, is capable of producing a uniform, dc magnetic field of about 0.35 T inside the plasma chamber of diameter 0.30 m. Support structure of the coils is planned in an innovative way facilitating straightforward fabrication and easy positioning of the coils. Further special feature lies in the arrangement of the spacers between the coils that can be maneuvered rather easily to create different magnetic configurations. Various methods of plasma production can be suitably utilized according to the experimental needs at either end of the vacuum vessel. In the present paper, characteristics of a steady state plasma generated by electron cyclotron resonance method using 2.45 GHz microwave power are presented. Scans using simple probe drives revealed that a uniform and long plasma column having electron density approximately 3-5x10(10) cm(-3) and temperature approximately 7-10 eV, is formed in the center of the plasma chamber which is suitable for wave launching experiments.

  20. Experiment Design for Nonparametric Models Based On Minimizing Bayes Risk: Application to Voriconazole1

    PubMed Central

    Bayard, David S.; Neely, Michael

    2016-01-01

    An experimental design approach is presented for individualized therapy in the special case where the prior information is specified by a nonparametric (NP) population model. Here, a nonparametric model refers to a discrete probability model characterized by a finite set of support points and their associated weights. An important question arises as to how to best design experiments for this type of model. Many experimental design methods are based on Fisher Information or other approaches originally developed for parametric models. While such approaches have been used with some success across various applications, it is interesting to note that they largely fail to address the fundamentally discrete nature of the nonparametric model. Specifically, the problem of identifying an individual from a nonparametric prior is more naturally treated as a problem of classification, i.e., to find a support point that best matches the patient’s behavior. This paper studies the discrete nature of the NP experiment design problem from a classification point of view. Several new insights are provided including the use of Bayes Risk as an information measure, and new alternative methods for experiment design. One particular method, denoted as MMopt (Multiple-Model Optimal), will be examined in detail and shown to require minimal computation while having distinct advantages compared to existing approaches. Several simulated examples, including a case study involving oral voriconazole in children, are given to demonstrate the usefulness of MMopt in pharmacokinetics applications. PMID:27909942

  1. Experiment design for nonparametric models based on minimizing Bayes Risk: application to voriconazole¹.

    PubMed

    Bayard, David S; Neely, Michael

    2017-04-01

    An experimental design approach is presented for individualized therapy in the special case where the prior information is specified by a nonparametric (NP) population model. Here, a NP model refers to a discrete probability model characterized by a finite set of support points and their associated weights. An important question arises as to how to best design experiments for this type of model. Many experimental design methods are based on Fisher information or other approaches originally developed for parametric models. While such approaches have been used with some success across various applications, it is interesting to note that they largely fail to address the fundamentally discrete nature of the NP model. Specifically, the problem of identifying an individual from a NP prior is more naturally treated as a problem of classification, i.e., to find a support point that best matches the patient's behavior. This paper studies the discrete nature of the NP experiment design problem from a classification point of view. Several new insights are provided including the use of Bayes Risk as an information measure, and new alternative methods for experiment design. One particular method, denoted as MMopt (multiple-model optimal), will be examined in detail and shown to require minimal computation while having distinct advantages compared to existing approaches. Several simulated examples, including a case study involving oral voriconazole in children, are given to demonstrate the usefulness of MMopt in pharmacokinetics applications.

  2. Using Evidence-Centered Design to Create a Special Educator Observation System

    ERIC Educational Resources Information Center

    Johnson, Evelyn S.; Crawford, Angela R.; Moylan, Laura A.; Zheng, Yuzhu

    2018-01-01

    The Evidence-Centered Design (ECD) framework was used to create a special education teacher observation system, Recognizing Effective Special Education Teachers (RESET). Extensive reviews of research informed the domain analysis and modeling stages, and led to the conceptual framework in which effective special education teaching is…

  3. 76 FR 10482 - Special Conditions: Boeing Model 787-8 Airplane; Overhead Flightcrew-Rest Compartment Occupiable...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-25

    ... Boeing Model 787-8 airplane. This airplane will have novel or unusual design features associated with an... standards for this design feature. These special conditions contain the additional safety standards that the... airworthiness standards. Additional special conditions will be issued for other novel or unusual design features...

  4. 45 CFR 670.25 - Designation of specially protected species of native mammals, birds, and plants.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... native mammals, birds, and plants. 670.25 Section 670.25 Public Welfare Regulations Relating to Public... Protected Species of Mammals, Birds, and Plants § 670.25 Designation of specially protected species of native mammals, birds, and plants. The following species has been designated as Specially Protected...

  5. 45 CFR 670.25 - Designation of specially protected species of native mammals, birds, and plants.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... native mammals, birds, and plants. 670.25 Section 670.25 Public Welfare Regulations Relating to Public... Protected Species of Mammals, Birds, and Plants § 670.25 Designation of specially protected species of native mammals, birds, and plants. The following species has been designated as Specially Protected...

  6. Designs for Organizing and Administering Special Education; Proceedings of a Cooperative Work-Conference (Atwood Lodge, Dellroy, Ohio, May 9-10, 1968).

    ERIC Educational Resources Information Center

    Birch, Jack W., Ed.

    Papers included are the following: design for organizing and administering special education by Paul R. Ackerman and William C. Geer; indications of patterns and trends in special education, by Marvin E. Beekman; the organization of special education services, by John W. Kidd; and organization and administration of special education, by Harrie M.…

  7. Histological changes induced by CO2 laser microprobe specially designed for root canal sterilization: in vivo study.

    PubMed

    Kesler, G; Koren, R; Kesler, A; Hay, N; Gal, R

    1998-10-01

    Until now, no suitable delivery fiber has existed for CO2 laser endodontic radiation in the apical region, where it is most difficult to eliminate the pulp tissue using conventional methods. To overcome this problem, we have designed a microprobe that reaches closer to the apex, distributing the energy density to a smaller area of the root canal and thus favorably increasing the thermal effects. A CO2 laser microprobe coupled onto a special hand piece was attached to the delivery fiber of a Sharplan 15-F CO2 laser. The study was conducted on 30 vital maxillary or mandibulary, central, lateral, or premolar teeth destined for extraction due to periodontal problems. Twenty were experimentally treated with pulsed CO2 laser delivered by this newly developed fiber after conventional root canal preparation. Temperature measured at three points on the root surface during laser treatment did not exceed 38 degrees C. Ten teeth represented the control group, in which only root canal preparation was performed in the conventional method. Histological examination of the laser-treated teeth showed coagulation necrosis and vacuolization of the remaining pulp tissue in the root canal periphery. Primary and secondary dentin appeared normal in all cases treated with 15-F CO2 laser. Gram stain and bacteriologic examination revealed complete sterilization. These results demonstrate the unique capabilities of this special microprobe in sterilization of the root canal, with no thermal damage to the surrounding tissue. The combination of classical root canal preparation with CO2 laser irradiation using this special microprobe before closing the canal can drastically change the quality of root canal fillings.

  8. Vibration analysis of a new polymer quartz piezoelectric crystal sensor for detecting characteristic materials of volatility liquid

    NASA Astrophysics Data System (ADS)

    Gu, Yu; Li, Qiang; Xu, Bao-Jun; Zhao, Zhe

    2014-01-01

    We present a new polymer quartz piezoelectric crystal sensor that takes a quartz piezoelectric crystal as the basal material and a nanometer nonmetallic polymer thin film as the surface coating based on the principle of quartz crystal microbalance (QCM). The new sensor can be used to detect the characteristic materials of a volatile liquid. A mechanical model of the new sensor was built, whose structure was a thin circle plate composing of polytef/quartz piezoelectric/polytef. The mechanical model had a diameter of 8 mm and a thickness of 170 μm. The vibration state of the model was simulated by software ANSYS after the physical parameters and the boundary condition of the new sensor were set. According to the results of experiments, we set up a frequency range from 9.995850 MHz to 9.997225 MHz, 17 kinds of frequencies and modes of vibration were obtained within this range. We found a special frequency fsp of 9.996358 MHz. When the resonant frequency of the new sensor's mechanical model reached the special frequency, a special phenomenon occurred. In this case, the amplitude of the center point O on the mechanical model reached the maximum value. At the same time, the minimum absolute difference between the simulated frequency based on the ANSYS software and the experimental measured stable frequency was reached. The research showed that the design of the new polymer quartz piezoelectric crystal sensor perfectly conforms to the principle of QCM. A special frequency value fsp was found and subsequently became one of the most important parameters in the new sensor design.

  9. Experimental setup for investigation of nanoclusters at cryogenic temperatures by electron spin resonance and optical spectroscopies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mao, S., E-mail: maoshunghost@tamu.edu; Meraki, A.; McColgan, P. T.

    2014-07-15

    We present the design and performance of an experimental setup for simultaneous electron spin resonance (ESR) and optical studies of nanoclusters with stabilized free radicals at cryogenic temperatures. A gas mixture of impurities and helium after passing through a RF discharge for dissociation of molecules is directed onto the surface of superfluid helium to form the nanoclusters of impurities. A specially designed ESR cavity operated in the TE{sub 011} mode allows optical access to the sample. The cavity is incorporated into a homemade insert which is placed inside a variable temperature insert of a Janis {sup 4}He cryostat. The temperaturemore » range for sample investigation is 1.25–300 K. A Bruker EPR 300E and Andor 500i optical spectrograph incorporated with a Newton EMCCD camera are used for ESR and optical registration, respectively. The current experimental system makes it possible to study the ESR and optical spectra of impurity-helium condensates simultaneously. The setup allows a broad range of research at low temperatures including optically detected magnetic resonance, studies of chemical processes of the active species produced by photolysis in solid matrices, and investigations of nanoclusters produced by laser ablation in superfluid helium.« less

  10. Experimental study of the response functions of direct-reading instruments measuring surface-area concentration of airborne nanostructured particles

    NASA Astrophysics Data System (ADS)

    Bau, Sébastien; Witschger, Olivier; Gensdarmes, François; Thomas, Dominique

    2009-05-01

    An increasing number of experimental and theoretical studies focus on airborne nanoparticles (NP) in relation with many aspects of risk assessment to move forward our understanding of the hazards, the actual exposures in the workplace, and the limits of engineering controls and personal protective equipment with regard to NP. As a consequence, generating airborne NP with controlled properties constitutes an important challenge. In parallel, toxicological studies have been carried out, and most of them support the concept that surface-area could be a relevant metric for characterizing exposure to airborne NP [1]. To provide NP surface-area concentration measurements, some direct-reading instruments have been designed, based on attachment rate of unipolar ions to NP by diffusion. However, very few information is available concerning the performances of these instruments and the parameters that could affect their responses. In this context, our work aims at characterizing the actual available instruments providing airborne NP surface-area concentration. The instruments (a- LQ1-DC, Matter Engineering; b-AeroTrak™ 9000, TSI; c- NSAM, TSI model 3550;) are thought to be relevant for further workplace exposure characterization and monitoring. To achieve our work, an experimental facility (named CAIMAN) was specially designed, built and characterized.

  11. Experimental analysis of internal rigid fixation osteosynthesis performed with titanium bone screw and plate systems.

    PubMed

    Righi, E; Carta, M; Bruzzone, A A; Lonardo, P M; Marinaro, E; Pastorino, A

    1996-02-01

    The authors report the results of an experimental analysis performed on titanium miniplates and screws in order to gain a better understanding of dynamic forces in internal rigid fixation. Ten segments of bovine scapula were prepared. Osteotomies were carried out along the minor axis, following which five were fixed with four hole straight miniplates and the other five with six hole double-Y miniplates. Each sample was fastened in a special clamp adapted to a tension test machine and shearing force was applied. Force versus time was recorded and the 50 bone fragments were examined by a pathologist. On the basis of the test results, two simple computer models were developed. No significant difference was evident between the mechanical and computed tests. The most critical sections were located near the hole proximal to the osteotomy and the microscopic findings confirmed this. On the basis of the experimental results, the authors propose a new plate design in which the area subject to most stress, proximal to the bone section, would be of miniplate thickness, the distal aspect being thinner as in a microplate. It is suggested that this design would provide sufficient stability and a high degree of anatomical adjustment of the system.

  12. Development and application of a specially designed heating system for temperature-programmed high-performance liquid chromatography using subcritical water as the mobile phase.

    PubMed

    Teutenberg, T; Goetze, H-J; Tuerk, J; Ploeger, J; Kiffmeyer, T K; Schmidt, K G; Kohorst, W gr; Rohe, T; Jansen, H-D; Weber, H

    2006-05-05

    A specially designed heating system for temperature-programmed HPLC was developed based on experimental measurements of eluent temperature inside a stainless steel capillary using a very thin thermocouple. The heating system can be operated at temperatures up to 225 degrees C and consists of a preheating, a column heating and a cooling unit. Fast cycle times after a temperature gradient can be realized by an internal silicone oil bath which cools down the preheating and column heating unit. Long-term thermal stability of a polybutadiene-coated zirconium dioxide column has been evaluated using a tubular oven in which the column was placed. The packing material was stable after 50h of operation at 185 degrees C. A mixture containing four steroids was separated at ambient conditions using a mobile phase of 25% acetonitrile:75% deionized water and a mobile phase of pure deionized water at 185 degrees C using the specially designed heating system and the PBD column. Analysis time could be drastically reduced from 17 min at ambient conditions and a flow rate of 1 mL/min to only 1.2 min at 185 degrees C and a flow rate of 5 mL/min. At these extreme conditions, no thermal mismatch was observed and peaks were not distorted, thus underlining the performance of the developed heating system. Temperature programming was performed by separating cytostatic and antibiotic drugs with a temperature gradient using only water as the mobile phase. In contrast to an isocratic elution of this mixture at room temperature, overall analysis time could be reduced two-fold from 20 to 10 min.

  13. Advanced technology development multi-color holography

    NASA Technical Reports Server (NTRS)

    Vikram, Chandra S.

    1993-01-01

    This is the final report of the Multi-color Holography project. The comprehensive study considers some strategic aspects of multi-color holography. First, various methods of available techniques for accurate fringe counting are reviewed. These are heterodyne interferometry, quasi-heterodyne interferometry, and phase-shifting interferometry. Phase-shifting interferometry was found to be the most suitable for multi-color holography. Details of experimentation with a sugar solution are also reported where better than 1/200 of a fringe order measurement capability was established. Rotating plate glass phase shifter was used for the experimentation. The report then describes the possible role of using more than two wavelengths with special reference-to-object beam intensity ratio needs in multicolor holography. Some specific two- and three-color cases are also described in detail. Then some new analysis methods of the reconstructed wavefront are considered. These are deflectometry, speckle metrology, confocal optical signal processing, and phase shifting technique related applications. Finally, design aspects of an experimental breadboard are presented.

  14. SUMOFLUX: A Generalized Method for Targeted 13C Metabolic Flux Ratio Analysis

    PubMed Central

    Kogadeeva, Maria

    2016-01-01

    Metabolic fluxes are a cornerstone of cellular physiology that emerge from a complex interplay of enzymes, carriers, and nutrients. The experimental assessment of in vivo intracellular fluxes using stable isotopic tracers is essential if we are to understand metabolic function and regulation. Flux estimation based on 13C or 2H labeling relies on complex simulation and iterative fitting; processes that necessitate a level of expertise that ordinarily preclude the non-expert user. To overcome this, we have developed SUMOFLUX, a methodology that is broadly applicable to the targeted analysis of 13C-metabolic fluxes. By combining surrogate modeling and machine learning, we trained a predictor to specialize in estimating flux ratios from measurable 13C-data. SUMOFLUX targets specific flux features individually, which makes it fast, user-friendly, applicable to experimental design and robust in terms of experimental noise and exchange flux magnitude. Collectively, we predict that SUMOFLUX's properties realistically pave the way to high-throughput flux analyses. PMID:27626798

  15. Multi Ray Model for Near-Ground Millimeter Wave Radar

    PubMed Central

    Litvak, Boris; Pinhasi, Yosef

    2017-01-01

    A quasi-optical multi-ray model for a short-range millimeter wave radar is presented. The model considers multi-path effects emerging while multiple rays are scattered from the target and reflected to the radar receiver. Among the examined scenarios, the special case of grazing ground reflections is analyzed. Such a case becomes relevant when short range anti-collision radars are employed in vehicles. Such radars operate at millimeter wavelengths, and are aimed at the detection of targets located several tens of meters from the transmitter. Reflections from the road are expected to play a role in the received signal strength, together with the direct line-of-sight beams illuminated and scattered from the target. The model is demonstrated experimentally using radar operating in the W-band. Controlled measurements were done to distinguish between several scattering target features. The experimental setup was designed to imitate vehicle near-ground millimeter wave radars operating in vehicles. A comparison between analytical calculations and experimental results is made and discussed. PMID:28867776

  16. RETRACTED ARTICLE: Quasi-distributed fiber bragg grating array sensor for furnace applications

    NASA Astrophysics Data System (ADS)

    Reddy, P. Saidi; Sai Prasad, R. L. N.; Sen Gupta, D.; Sai Shankar, M.; Srimannarayana, K.; Ravinder Reddy, P.

    2012-05-01

    An experimental work on distributed temperature sensing making use of the fiber Bragg grating (FBG) array sensor for possible applications in the monitoring of the temperature profile in high temperature boilers is presented. A special sensor has been designed for this purpose which consists of four FBGs (of wavelengths λ B1 =1545.8 nm, λ B2 =1547 nm, λ B3 =1550.8 nm, λ B4 =1555.5 nm at 30 °C) written in the hydrogen-loaded fiber in line. All the FBGs are encapsulated inside a stainless steel tube using the rigid probe technique for avoiding micro cracks. The spatial distribution of the temperature profile inside a prototype boiler was measured experimentally both in horizontal and vertical directions employing the above sensor, and the results are presented. Further, the finite element simulation has been carried out by using ANSYS R11 software to predict temperature contours in the boiler, and the experimental and predicted results were found to be closely matching.

  17. Tips and Tricks for Successful Application of Statistical Methods to Biological Data.

    PubMed

    Schlenker, Evelyn

    2016-01-01

    This chapter discusses experimental design and use of statistics to describe characteristics of data (descriptive statistics) and inferential statistics that test the hypothesis posed by the investigator. Inferential statistics, based on probability distributions, depend upon the type and distribution of the data. For data that are continuous, randomly and independently selected, as well as normally distributed more powerful parametric tests such as Student's t test and analysis of variance (ANOVA) can be used. For non-normally distributed or skewed data, transformation of the data (using logarithms) may normalize the data allowing use of parametric tests. Alternatively, with skewed data nonparametric tests can be utilized, some of which rely on data that are ranked prior to statistical analysis. Experimental designs and analyses need to balance between committing type 1 errors (false positives) and type 2 errors (false negatives). For a variety of clinical studies that determine risk or benefit, relative risk ratios (random clinical trials and cohort studies) or odds ratios (case-control studies) are utilized. Although both use 2 × 2 tables, their premise and calculations differ. Finally, special statistical methods are applied to microarray and proteomics data, since the large number of genes or proteins evaluated increase the likelihood of false discoveries. Additional studies in separate samples are used to verify microarray and proteomic data. Examples in this chapter and references are available to help continued investigation of experimental designs and appropriate data analysis.

  18. Test Methodology Development for Experimental Structural Assessment of ASC Planar Spring Material for Long-Term Durability

    NASA Technical Reports Server (NTRS)

    Yun, Gunjin; Abdullah, A. B. M.; Binienda, Wieslaw; Krause, David L.; Kalluri, Sreeramesh

    2014-01-01

    A vibration-based testing methodology has been developed that will assess fatigue behavior of the metallic material of construction for the Advanced Stirling Convertor displacer (planar) spring component. To minimize the testing duration, the test setup is designed for base-excitation of a multiplespecimen arrangement, driven in a high-frequency resonant mode; this allows completion of fatigue testing in an accelerated period. A high performance electro-dynamic exciter (shaker) is used to generate harmonic oscillation of cantilever beam specimens, which are clasped on the shaker armature with specially-designed clamp fixtures. The shaker operates in closed-loop control with dynamic specimen response feedback provided by a scanning laser vibrometer. A test coordinator function synchronizes the shaker controller and the laser vibrometer to complete the closed-loop scheme. The test coordinator also monitors structural health of the test specimens throughout the test period, recognizing any change in specimen dynamic behavior. As this may be due to fatigue crack initiation, the test coordinator terminates test progression and then acquires test data in an orderly manner. Design of the specimen and fixture geometry was completed by finite element analysis such that peak stress does not occur at the clamping fixture attachment points. Experimental stress evaluation was conducted to verify the specimen stress predictions. A successful application of the experimental methodology was demonstrated by validation tests with carbon steel specimens subjected to fully-reversed bending stress; high-cycle fatigue failures were induced in such specimens using higher-than-prototypical stresses

  19. Investigation of microgravity effects on solidification phenomena of selected materials

    NASA Technical Reports Server (NTRS)

    Maag, Carl R.; Hansen, Patricia A.

    1992-01-01

    A Get Away Special (GAS) experiment payload to investigate microgravity effects on solidification phenomena of selected experimental samples has been designed for flight. It is intended that the first flight of the assembly will (1) study the p-n junction characteristics for advancing semiconductor device applications, (2) study the effects of gravity-driven convection on the growth of HgCd crystals, (3) compare the textures of the sample which crystallizes in microgravity with those found in chondrite meteorites, and (4) modify glass optical characteristics through divalent oxygen exchange. The space flight experiment consists of many small furnaces. While the experiment payload is in the low gravity environment of orbital flight, the payload controller will sequentially activate the furnaces to heat samples to their melt state and then allow cooling to resolidification in a controlled fashion. The materials processed in the microgravity environment of space will be compared to the same materials processed on earth in a one-gravity environment. This paper discusses the design of all subassemblies (furnance, electronics, and power systems) in the experiment. A complete description of the experimental materials is also presented.

  20. Self-Assembly and Nanostructures in Organogels Based on a Bolaform Cholesteryl Imide Compound with Conjugated Aromatic Spacer

    PubMed Central

    Jiao, Ti-Feng; Gao, Feng-Qing; Shen, Xi-Hai; Zhang, Qing-Rui; Zhang, Xian-Fu; Zhou, Jing-Xin; Gao, Fa-Ming

    2013-01-01

    The self-assembly of small functional molecules into supramolecular structures is a powerful approach toward the development of new nanoscale materials and devices. As a class of self-assembled materials, low weight molecular organic gelators, organized in special nanoarchitectures through specific non-covalent interactions, has become one of the hot topics in soft matter research due to their scientific values and many potential applications. Here, a bolaform cholesteryl imide compound with conjugated aromatic spacer was designed and synthesized. The gelation behaviors in 23 solvents were investigated as efficient low-molecular-mass organic gelator. The experimental results indicated that the morphologies and assembly modes of as-formed organogels can be regulated by changing the kinds of organic solvents. Scanning electron microscopy and atomic force microscopy observations revealed that the gelator molecule self-assemble into different aggregates, from wrinkle and belt to fiber with the change of solvents. Spectral studies indicated that there existed different H-bond formations between imide groups and assembly modes. Finally, some rational assembly modes in organogels were proposed and discussed. The present work may give some insight to the design and character of new organogelators and soft materials with special structures. PMID:28788428

  1. Data-driven multi-scale multi-physics models to derive process-structure-property relationships for additive manufacturing

    NASA Astrophysics Data System (ADS)

    Yan, Wentao; Lin, Stephen; Kafka, Orion L.; Lian, Yanping; Yu, Cheng; Liu, Zeliang; Yan, Jinhui; Wolff, Sarah; Wu, Hao; Ndip-Agbor, Ebot; Mozaffar, Mojtaba; Ehmann, Kornel; Cao, Jian; Wagner, Gregory J.; Liu, Wing Kam

    2018-05-01

    Additive manufacturing (AM) possesses appealing potential for manipulating material compositions, structures and properties in end-use products with arbitrary shapes without the need for specialized tooling. Since the physical process is difficult to experimentally measure, numerical modeling is a powerful tool to understand the underlying physical mechanisms. This paper presents our latest work in this regard based on comprehensive material modeling of process-structure-property relationships for AM materials. The numerous influencing factors that emerge from the AM process motivate the need for novel rapid design and optimization approaches. For this, we propose data-mining as an effective solution. Such methods—used in the process-structure, structure-properties and the design phase that connects them—would allow for a design loop for AM processing and materials. We hope this article will provide a road map to enable AM fundamental understanding for the monitoring and advanced diagnostics of AM processing.

  2. Data-driven multi-scale multi-physics models to derive process-structure-property relationships for additive manufacturing

    NASA Astrophysics Data System (ADS)

    Yan, Wentao; Lin, Stephen; Kafka, Orion L.; Lian, Yanping; Yu, Cheng; Liu, Zeliang; Yan, Jinhui; Wolff, Sarah; Wu, Hao; Ndip-Agbor, Ebot; Mozaffar, Mojtaba; Ehmann, Kornel; Cao, Jian; Wagner, Gregory J.; Liu, Wing Kam

    2018-01-01

    Additive manufacturing (AM) possesses appealing potential for manipulating material compositions, structures and properties in end-use products with arbitrary shapes without the need for specialized tooling. Since the physical process is difficult to experimentally measure, numerical modeling is a powerful tool to understand the underlying physical mechanisms. This paper presents our latest work in this regard based on comprehensive material modeling of process-structure-property relationships for AM materials. The numerous influencing factors that emerge from the AM process motivate the need for novel rapid design and optimization approaches. For this, we propose data-mining as an effective solution. Such methods—used in the process-structure, structure-properties and the design phase that connects them—would allow for a design loop for AM processing and materials. We hope this article will provide a road map to enable AM fundamental understanding for the monitoring and advanced diagnostics of AM processing.

  3. The Design of an Autonomous Underwater Vehicle for Water Quality Monitoring

    NASA Astrophysics Data System (ADS)

    Li, Yulong; Liu, Rong; Liu, Shujin

    2018-01-01

    This paper describes the development of a civilian-used autonomous underwater vehicle (AUV) for water quality monitoring at reservoirs and watercourses that can obtain realtime visual and locational information. The mechanical design was completed with CAD software Solidworks. Four thrusters—two horizontal and two vertical—on board enable the vehicle to surge, heave, yaw, and pitch. A specialized water sample collection compartment is designed to perform water collection at target locations. The vehicle has a central controller—STM32—and a sub-coordinate controller—Arduino MEGA 2560—that coordinates multiple sensors including an inertial sensor, ultrasonic sensors, etc. Global Navigation Satellite System (GNSS) and the inertial sensor enable the vehicle’s localization. Remote operators monitor and control the vehicle via a host computer system. Operators choose either semi-autonomous mode in which they set target locations or manual mode. The experimental results show that the vehicle is able to perform well in either mode.

  4. Design Parameters and Objectives of a High-­Resolution X-­ray Imaging Crystal Spectrometer for the Large Helical Device (LHD)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bitter, M; Gates, D; Neilson, H

    A high-resolution X-ray imaging crystal spectrometer, whose instrumental concept was thoroughly tested on NSTX and Alcator C-Mod, is presently being designed for LHD. The instrument will record spatially resolved spectra of helium-like Ar16+ and provide ion temperature profiles with spatial and temporal resolutions of 1 cm and > 10 ms which are obtained by a tomographic inversion of the spectral data, using the stellarator equilibrium reconstruction codes, STELLOPT and PIES. Since the spectrometer will be equipped with radiation hardened, high count rate, PILATUS detectors,, it is expected to be operational for all experimental conditions on LHD, which include plasmas ofmore » high density and plasmas with auxiliary RF and neutral beam heating. The special design features required by the magnetic field structure at LHD will be described.« less

  5. IMAGE Project: Results of Laboratory Tests on Tracers for Supercritical Conditions.

    NASA Astrophysics Data System (ADS)

    Brandvoll, Øyvind; Opsahl Viig, Sissel; Nardini, Isabella; Muller, Jiri

    2016-04-01

    The use of tracers is a well-established technique for monitoring dynamic behaviour of water and gas through a reservoir. In geothermal reservoirs special challenges are encountered due to high temperatures and pressures. In this work, tracer candidates for monitoring water at supercritical conditions (temperature > 374°C, pressure ca 218 bar), are tested in laboratory experiments. Testing of tracers at supercritical water conditions requires experimental set-ups which tolerate harsh conditions with respect to high temperature and pressure. In addition stringent HES (health, environment and safety) factors have to be taken into consideration when designing and performing the experiments. The setup constructed in this project consists of a pressure vessel, high pressure pump, instrumentation for pressure and temperature control and instrumentation required for accurate sampling of tracers. In order to achieve accurate results, a special focus has been paid to the development of the tracer sampling technique. Perfluorinated cyclic hydrocarbons (PFCs) have been selected as tracer candidates. This group of compounds is today commonly used as gas tracers in oil reservoirs. According to the literature they are stable at temperatures up to 400°C. To start with, five PFCs have been tested for thermal stability in static experiments at 375°C and 108 bar in the experimental setup described above. The tracer candidates will be further tested for several months at the relevant conditions. Preliminary results indicate that some of the PFC compounds show stability after three months. However, in order to arrive at conclusive results, the experiments have to be repeated over a longer period and paying special attention to more accurate sampling procedures.

  6. Dynamic properties of ionospheric plasma turbulence driven by high-power high-frequency radiowaves

    NASA Astrophysics Data System (ADS)

    Grach, S. M.; Sergeev, E. N.; Mishin, E. V.; Shindin, A. V.

    2016-11-01

    A review is given of the current state-of-the-art of experimental studies and the theoretical understanding of nonlinear phenomena that occur in the ionospheric F-layer irradiated by high-power high-frequency ground-based transmitters. The main focus is on the dynamic features of high-frequency turbulence (plasma waves) and low-frequency turbulence (density irregularities of various scales) that have been studied in experiments at the Sura and HAARP heating facilities operated in temporal and frequency regimes specially designed with consideration of the characteristic properties of nonlinear processes in the perturbed ionosphere using modern radio receivers and optical instruments. Experimental results are compared with theoretical turbulence models for a magnetized collisional plasma in a high-frequency electromagnetic field, allowing the identification of the processes responsible for the observed features of artificial ionospheric turbulence.

  7. Experimental Investigation of Effectiveness of Magnetic Field on Food Freezing Process

    NASA Astrophysics Data System (ADS)

    Suzuki, Toru; Takeuchi, Yuri; Masuda, Kazunori; Watanabe, Manabu; Shirakashi, Ryo; Fukuda, Yutaka; Tsuruta, Takaharu; Yamamoto, Kazutaka; Koga, Nobumitsu; Hiruma, Naoya; Ichioka, Jun; Takai, Kiyoshi

    Recently, several food refrigeration equipments that utilize magnetic field have attracted much attention from food production companies, consumers and mass media. However, the effectiveness of the freezers is not scientifically examined. Therefore, the effectiveness should be clarified by experiments or theoretical considerations. In this study, the effect of weak magnetic field (about 0.0005 T) on freezing process of several kinds of foods was investigated by using a specially designed freezer facilitated with magnetic field generator. The investigation included the comparison of freezing curves, drip amount, physicochemical evaluations on color and texture, observation of microstructure, and sensory evaluation. From the results of the control experiments, it can be concluded that weak magnetic field around 0.0005 T provided no significant difference on temperature history during freezing and on the qualities of frozen foods, within our experimental conditions.

  8. Fiber Bragg Grating Array as a Quasi Distributed Temperature Sensor for Furnace Boiler Applications

    NASA Astrophysics Data System (ADS)

    Reddy, P. Saidi; Prasad, R. L. N. Sai; Sengupta, D.; Shankar, M. Sai; Srimannarayana, K.; Kishore, P.; Rao, P. Vengal

    2011-10-01

    This paper presents the experimental work on distributed temperature sensing making use of Fiber Bragg grating (FBG) array sensor for possible applications in the monitoring of temperature profile in high temperature boilers. A special sensor has been designed for this purpose which consists of four FBGs (of wavelengths λB1 = 1547.28 nm, λB2 = 1555.72 nm, λB3 = 1550.84 nm, λB4 = 1545.92 nm) written in hydrogen loaded fiber in line with a spacing of 15 cm between them. All the FBGs are encapsulated inside a stainless steel tube for avoiding micro cracks using rigid probe technique. The spatial distribution of temperature profile inside a prototype boiler has been measured experimentally both in horizontal and vertical directions employing the above sensor and the results are presented.

  9. Experimental study of the reversible behavior of modulational instability in optical fibers

    NASA Astrophysics Data System (ADS)

    van Simaeys, Gaetan; Emplit, Philippe; Haelterman, Marc

    2002-03-01

    We report what is to our knowledge the first clear-cut experimental evidence of the reversibility of modulational instability in dispersive Kerr media. It was possible to perform this experiment with standard telecommunication fiber because we used a specially designed 550-ps square-pulse laser source based on the two-wavelength configuration of a nonlinear optical loop mirror. Our observations demonstrate that reversibility is due to well-balanced and synchronous energy transfer among a significant number of spectral wave components. These results provide what we believe is the first evidence, in the field of nonlinear optics, of the universal Fermi-Pasta-Ulam recurrence phenomenon that has been predicted for a large number of conservative nonlinear systems, including those described by a nonlinear Schrödinger equation that is relevant to the context of the present study.

  10. A model describing vestibular detection of body sway motion.

    NASA Technical Reports Server (NTRS)

    Nashner, L. M.

    1971-01-01

    An experimental technique was developed which facilitated the formulation of a quantitative model describing vestibular detection of body sway motion in a postural response mode. All cues, except vestibular ones, which gave a subject an indication that he was beginning to sway, were eliminated using a specially designed two-degree-of-freedom platform; body sway was then induced and resulting compensatory responses at the ankle joints measured. Hybrid simulation compared the experimental results with models of the semicircular canals and utricular otolith receptors. Dynamic characteristics of the resulting canal model compared closely with characteristics of models which describe eye movement and subjective responses to body rotational motions. The average threshold level, in the postural response mode, however, was considerably lower. Analysis indicated that the otoliths probably play no role in the initial detection of body sway motion.

  11. Experimental facility for the study of acoustic emission registered in the primary circuit components of WWER power units

    NASA Astrophysics Data System (ADS)

    Petrosyan, V. G.; Hovakimyan, T. H.; Yeghoyan, E. A.; Hovhannisyan, H. T.; Mayilyan, D. G.; Petrosyan, A. P.

    2017-01-01

    This paper is dedicated to the creation of a facility for the experimental study of a phenomenon of background acoustic emission (AE), which is detected in the main circulation loop (MCL) of WWER power units. The analysis of the operating principle and the design of a primary feed-and-blow down system (FB) deaerator of NPP as the most likely source of continuous acoustic emission is carried out. The experimental facility for the systematic study of a phenomenon of continuous AE is developed. A physical model of a thermal deaerator is designed and constructed. A thermal monitoring system is introduced. An automatic system providing acoustic signal registration in a low frequency (0.03-30 kHz) and high frequency (30-300 kHz) bands and study of its spectral characteristics is designed. Special software for recording and processing of digitized electrical sensor signals is developed. A separate and independent principle of study of the most probable processes responsible for the generation of acoustic emission signals in the deaerator is applied. Trial series of experiments and prechecks of acoustic signals in different modes of the deaerator model are conducted. Compliance of basic technological parameters with operating range of the real deaerator was provided. It is shown that the acoustic signal time-intensity curve has several typical regions. The pilot research showed an impact of various processes that come about during the operation of the deaerator physical model on the intensity of the AE signal. The experimental results suggest that the main sources of generation of the AE signals are the processes of steam condensation, turbulent flow of gas-vapor medium, and water boiling.

  12. Simulator certification methods and the vertical motion simulator

    NASA Technical Reports Server (NTRS)

    Showalter, T. W.

    1981-01-01

    The vertical motion simulator (VMS) is designed to simulate a variety of experimental helicopter and STOL/VTOL aircraft as well as other kinds of aircraft with special pitch and Z axis characteristics. The VMS includes a large motion base with extensive vertical and lateral travel capabilities, a computer generated image visual system, and a high speed CDC 7600 computer system, which performs aero model calculations. Guidelines on how to measure and evaluate VMS performance were developed. A survey of simulation users was conducted to ascertain they evaluated and certified simulators for use. The results are presented.

  13. DEVELOPMENT OF COLD CLIMATE HEAT PUMP USING TWO-STAGE COMPRESSION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shen, Bo; Rice, C Keith; Abdelaziz, Omar

    2015-01-01

    This paper uses a well-regarded, hardware based heat pump system model to investigate a two-stage economizing cycle for cold climate heat pump applications. The two-stage compression cycle has two variable-speed compressors. The high stage compressor was modelled using a compressor map, and the low stage compressor was experimentally studied using calorimeter testing. A single-stage heat pump system was modelled as the baseline. The system performance predictions are compared between the two-stage and single-stage systems. Special considerations for designing a cold climate heat pump are addressed at both the system and component levels.

  14. Supercritical Fluid Extraction of Toxic Heavy Metals and Uranium from Acidic Solutions with Sulfur-Containing Organophosphorus Reagents

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lin, Yuehe; Liu, Chongxuan; Wu, Hong

    2003-03-02

    The feasibility of using sulfur-containing organophosphorus reagents for the chelation-supercritical fluid extraction (SFE) of toxic heavy metals and uranium from acidic media was investigated. The SFE experiments were conducted in a specially-designed flow-through liquid extractor. Effective extraction of the metal ions from various acidic media was demonstrated. The effect of ligand concentration in supercritical CO{sub 2} on the kinetics of metal extraction was studied. A simplified model is used to describe the extraction kinetics and the good agreement of experimental data with the equilibrium-based model is achieved.

  15. Reviews

    NASA Astrophysics Data System (ADS)

    2007-09-01

    WE RECOMMEND Energy Foresight Valuable and original GCSE curriculum support on DVD Developing Scientific Literacy: Using News Media in the Classroom This book helpfully evaluates science stories in today's media Radioactivity Explained and Electricity Explained Interactive software ideal for classroom use TEP Generator Wind-up generator specially designed for schools SEP Energymeter A joule meter with more uses than its appearance suggests Into the Cool: Energy Flow, Thermodynamics and Life This book explores the physics behind biology CmapTools Handy software for mapping knowledge and resources LogIT Black Box This hub contains multiple sensors for endless experimental fun WEB WATCH Water Web 2.0

  16. Development turbine blade for ultramicro hydro power generation by 3D printer system

    NASA Astrophysics Data System (ADS)

    Kamimura, T.; Itoh, H.; Sugiura, K.

    2017-11-01

    We have developed micro generation system for effective use of unutilized energy and the spread of a self-controlled dispersion energy supply system. The turbine blade was designed for achieving high performance by special shape. The turbine type was called quasi-Peace turbine type. Turbine with a diameter of 30cm is made of metal, it was created by the 5-axis milling machine. The experimental apparatus was fabricated by the 3D printer. An experiment was carried out in the scale down model. The specific speed of this turbine was much lower than that of existing turbines.

  17. Repetitively pulsed TEA CO{sub 2} laser and its application for second harmonic generation in ZnGeP{sub 2} crystal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koval'chuk, L V; Grezev, A N; Niz'ev, V G

    2015-10-31

    Experimental results are presented on the development of a radiation source emitting at a wavelength of 4.775 μm with a pulse energy up to 50 mJ and an average power up to several watts in short pulse trains. A TEA CO{sub 2} laser and a nonlinear converter based on a ZnGeP{sub 2} crystal, which are specially designed for these experiments, are described. The main limitations of nonlinear conversion and possible ways to overcome these limitations are considered. (lasers)

  18. Experimental investigation of recirculating cells in laminar coaxial jets.

    NASA Technical Reports Server (NTRS)

    Warpinski, N. R.; Nagib, H. M.; Lavan, Z.

    1972-01-01

    Utilizing several unique means of introducing smoke into the flow field for careful visualization in addition to hot-wire techniques, experiments are performed in a specially designed facility producing laminar flows up to considerably high Reynolds numbers. Characteristics of the cells and the flow conditions that bring them about are documented by smoke photographs in the Reynolds number velocity ratio plane and the results are compared to previous analytical predictions. The cells are found to fall into three categories with different flow characteristics involving unsteadiness in position, and shear layer instabilities which result in higher mixing with the outer streams.-

  19. Manufacturing techniques for gyroscopes in gravity probe B

    NASA Technical Reports Server (NTRS)

    Rasquin, J. R.

    1976-01-01

    The design of the fused silica gyroscope configuration is presented. The first gyroscope was made for erection and spin tests only and does not contain the angle readout loops necessary for a functioning experimental gyroscope. The rotor ball described is not coated with the ultimate material, niobium, but instead with a sandwich of titanium, cooper, and titanium for spin-up test purposes. Background, historical information, manufacturing procedures, and sketches for this gyroscope are included to provide a better understanding of the device and the techniques and special tools required to manufacture a fused silica gyroscope to the required specifications.

  20. Hormone purification by isoelectric focusing in space

    NASA Technical Reports Server (NTRS)

    Bier, M.

    1982-01-01

    The performance of a ground-prototype of an apparatus for recycling isoelectric focusing was evaluated in an effort to provide technology for large scale purification of peptide hormones, proteins, and other biologicals. Special emphasis was given to the effects of gravity on the function of the apparatus and to the determination of potential advantages deriveable from its use in a microgravity environment. A theoretical model of isoelectric focusing sing chemically defined buffer systems for the establishment of the pH gradients was developed. The model was transformed to a form suitable for computer simulations and was used extensively for the design of experimental buffers.

  1. Are WISC IQ scores in children with mathematical learning disabilities underestimated? The influence of a specialized intervention on test performance.

    PubMed

    Lambert, Katharina; Spinath, Birgit

    2018-01-01

    Intelligence measures play a pivotal role in the diagnosis of mathematical learning disabilities (MLD). Probably as a result of math-related material in IQ tests, children with MLD often display reduced IQ scores. However, it remains unclear whether the effects of math remediation extend to IQ scores. The present study investigated the impact of a special remediation program compared to a control group receiving private tutoring (PT) on the WISC IQ scores of children with MLD. We included N=45 MLD children (7-12 years) in a study with a pre- and post-test control group design. Children received remediation for two years on average. The analyses revealed significantly greater improvements in the experimental group on the Full-Scale IQ, and the Verbal Comprehension, Perceptual Reasoning, and Working Memory indices, but not Processing Speed, compared to the PT group. Children in the experimental group showed an average WISC IQ gain of more than ten points. Results indicate that the WISC IQ scores of MLD children might be underestimated and that an effective math intervention can improve WISC IQ test performance. Taking limitations into account, we discuss the use of IQ measures more generally for defining MLD in research and practice. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. 45 CFR 670.29 - Designation of Antarctic Specially Protected Areas, Specially Managed Areas and Historic Sites...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... for special management and are hereby designated as Antarctic Specially Managed Areas (ASMA). Detailed..., Arlington, Virginia 22230. ASMA 1Admiralty Bay, King George Island, South Shetland Islands ASMA 2McMurdo Dry Valleys, Southern Victoria Land ASMA 3Cape Denison, Commonwealth Bay, George V Land ASMA 4Deception Island...

  3. 45 CFR 670.29 - Designation of Antarctic Specially Protected Areas, Specially Managed Areas and Historic Sites...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... for special management and are hereby designated as Antarctic Specially Managed Areas (ASMA). Detailed..., Arlington, Virginia 22230. ASMA 1Admiralty Bay, King George Island, South Shetland Islands ASMA 2McMurdo Dry Valleys, Southern Victoria Land ASMA 3Cape Denison, Commonwealth Bay, George V Land ASMA 4Deception Island...

  4. Novel Robotic Platforms for the Accurate Sampling and Monitoring of Water Columns

    PubMed Central

    Fernández, Roemi; Apalkov, Andrey; Armada, Manuel

    2016-01-01

    The hydrosphere contains large amounts of suspended particulate material, including living and non-living material that can be found in different compositions and concentrations, and that can be composed of particles of different sizes. The study of this particulate material along water columns plays a key role in understanding a great variety of biological, chemical, and physical processes. This paper presents the conceptual design of two patented robotic platforms that have been conceived for carrying out studies of water properties at desired depths with very high accuracy in the vertical positioning. One platform has been specially designed for operating near to a reservoir bottom, while the other is intended to be used near the surface. Several experimental tests have been conducted in order to validate the proposed approaches. PMID:27589745

  5. Experimental Investigation of a Piezo-Optical Transducer for Highly Sensitive Strain Gauges

    NASA Astrophysics Data System (ADS)

    Paulish, A. G.; Zagubisalo, P. S.; Barakov, V. N.; Pavlov, M. A.

    2018-03-01

    The characteristics of a piezo-optical transducer of a new design with high strain sensitivity at compact size have been studied.The original form of the photoelastic element provides a considerable increase in the stress in its working area at a given external force, resulting in an increase in the sensitivity of the transducer. The main characteristics of the transducer were measured using a specially designed device. The strain at a given applied force was calculated using a developed mathematical model of the transducer. As a result, the sensitivity to the relative strain was Δ x/ x=3 · 10-10, the dynamic range was at least four orders of magnitude higher and the gauge factor three orders of magnitude higher than those of strain-resistive gauges.

  6. IOTA (Integrable Optics Test Accelerator): Facility and experimental beam physics program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Antipov, Sergei; Broemmelsiek, Daniel; Bruhwiler, David

    The Integrable Optics Test Accelerator (IOTA) is a storage ring for advanced beam physics research currently being built and commissioned at Fermilab. It will operate with protons and electrons using injectors with momenta of 70 and 150 MeV/c, respectively. The research program includes the study of nonlinear focusing integrable optical beam lattices based on special magnets and electron lenses, beam dynamics of space-charge effects and their compensation, optical stochastic cooling, and several other experiments. In this article, we present the design and main parameters of the facility, outline progress to date and provide the timeline of the construction, commissioning andmore » research. Finally, the physical principles, design, and hardware implementation plans for the major IOTA experiments are also discussed.« less

  7. IOTA (Integrable Optics Test Accelerator): Facility and experimental beam physics program

    DOE PAGES

    Antipov, Sergei; Broemmelsiek, Daniel; Bruhwiler, David; ...

    2017-03-06

    The Integrable Optics Test Accelerator (IOTA) is a storage ring for advanced beam physics research currently being built and commissioned at Fermilab. It will operate with protons and electrons using injectors with momenta of 70 and 150 MeV/c, respectively. The research program includes the study of nonlinear focusing integrable optical beam lattices based on special magnets and electron lenses, beam dynamics of space-charge effects and their compensation, optical stochastic cooling, and several other experiments. In this article, we present the design and main parameters of the facility, outline progress to date and provide the timeline of the construction, commissioning andmore » research. Finally, the physical principles, design, and hardware implementation plans for the major IOTA experiments are also discussed.« less

  8. AC losses and stability on large cable-in-conduit superconductors

    NASA Astrophysics Data System (ADS)

    Bruzzone, Pierluigi

    1998-12-01

    The cable-in-conduit superconductors are preferred for applications where the AC losses and stability are a major concern, e.g., fusion magnets and SMES. A review of coupling currents loss results for both NbTi and Nb 3Sn cable-in-conduit conductors (CICC) is presented and the AC loss relevant features are listed, with special emphasis for the role of the interstrand resistance and strand coating. The transient stability approach for CICCs is discussed and the analytical models are quoted as well as the relevant experimental database. The likely spectrum of transient disturbance in CICC is reviewed and the need to account for interstrand current sharing in the design is outlined. Eventually a practical criterion for the interstrand resistance is proposed to link the stability and AC loss design.

  9. Development of land based radar polarimeter processor system

    NASA Technical Reports Server (NTRS)

    Kronke, C. W.; Blanchard, A. J.

    1983-01-01

    The processing subsystem of a land based radar polarimeter was designed and constructed. This subsystem is labeled the remote data acquisition and distribution system (RDADS). The radar polarimeter, an experimental remote sensor, incorporates the RDADS to control all operations of the sensor. The RDADS uses industrial standard components including an 8-bit microprocessor based single board computer, analog input/output boards, a dynamic random access memory board, and power supplis. A high-speed digital electronics board was specially designed and constructed to control range-gating for the radar. A complete system of software programs was developed to operate the RDADS. The software uses a powerful real time, multi-tasking, executive package as an operating system. The hardware and software used in the RDADS are detailed. Future system improvements are recommended.

  10. Determination of Material Constitutive Laws for Inconel 718 Superalloy Under Different Strain Rates and Working Temperatures

    NASA Astrophysics Data System (ADS)

    Grzesik, W.; Niesłony, P.; Laskowski, P.

    2017-12-01

    In this paper, a special procedure for the prediction of parameters of the Johnson-Cook constitutive material models is proposed based on the experimental data and specially developed MATLAB scripts which allow advanced modeling of complex 3D response surfaces. Experimental investigations concern two various strain rates of 10-3 and 101 1/s and the testing temperature ranging from the ambient up to 700 °C. As a result, a set of mathematical equations which fit the experimental data is determined. The applicability of the experimentally derived constitutive models to the FEM modeling of real machining processes of Inconel 718 alloy is verified.

  11. Simplified Estimation and Testing in Unbalanced Repeated Measures Designs.

    PubMed

    Spiess, Martin; Jordan, Pascal; Wendt, Mike

    2018-05-07

    In this paper we propose a simple estimator for unbalanced repeated measures design models where each unit is observed at least once in each cell of the experimental design. The estimator does not require a model of the error covariance structure. Thus, circularity of the error covariance matrix and estimation of correlation parameters and variances are not necessary. Together with a weak assumption about the reason for the varying number of observations, the proposed estimator and its variance estimator are unbiased. As an alternative to confidence intervals based on the normality assumption, a bias-corrected and accelerated bootstrap technique is considered. We also propose the naive percentile bootstrap for Wald-type tests where the standard Wald test may break down when the number of observations is small relative to the number of parameters to be estimated. In a simulation study we illustrate the properties of the estimator and the bootstrap techniques to calculate confidence intervals and conduct hypothesis tests in small and large samples under normality and non-normality of the errors. The results imply that the simple estimator is only slightly less efficient than an estimator that correctly assumes a block structure of the error correlation matrix, a special case of which is an equi-correlation matrix. Application of the estimator and the bootstrap technique is illustrated using data from a task switch experiment based on an experimental within design with 32 cells and 33 participants.

  12. Scalable, Lightweight, Integrated and Quick-to-Assemble (SLIQ) Hyperdrives for Functional Circuit Dissection.

    PubMed

    Liang, Li; Oline, Stefan N; Kirk, Justin C; Schmitt, Lukas Ian; Komorowski, Robert W; Remondes, Miguel; Halassa, Michael M

    2017-01-01

    Independently adjustable multielectrode arrays are routinely used to interrogate neuronal circuit function, enabling chronic in vivo monitoring of neuronal ensembles in freely behaving animals at a single-cell, single spike resolution. Despite the importance of this approach, its widespread use is limited by highly specialized design and fabrication methods. To address this, we have developed a Scalable, Lightweight, Integrated and Quick-to-assemble multielectrode array platform. This platform additionally integrates optical fibers with independently adjustable electrodes to allow simultaneous single unit recordings and circuit-specific optogenetic targeting and/or manipulation. In current designs, the fully assembled platforms are scalable from 2 to 32 microdrives, and yet range 1-3 g, light enough for small animals. Here, we describe the design process starting from intent in computer-aided design, parameter testing through finite element analysis and experimental means, and implementation of various applications across mice and rats. Combined, our methods may expand the utility of multielectrode recordings and their continued integration with other tools enabling functional dissection of intact neural circuits.

  13. A general approach for sample size calculation for the three-arm 'gold standard' non-inferiority design.

    PubMed

    Stucke, Kathrin; Kieser, Meinhard

    2012-12-10

    In the three-arm 'gold standard' non-inferiority design, an experimental treatment, an active reference, and a placebo are compared. This design is becoming increasingly popular, and it is, whenever feasible, recommended for use by regulatory guidelines. We provide a general method to calculate the required sample size for clinical trials performed in this design. As special cases, the situations of continuous, binary, and Poisson distributed outcomes are explored. Taking into account the correlation structure of the involved test statistics, the proposed approach leads to considerable savings in sample size as compared with application of ad hoc methods for all three scale levels. Furthermore, optimal sample size allocation ratios are determined that result in markedly smaller total sample sizes as compared with equal assignment. As optimal allocation makes the active treatment groups larger than the placebo group, implementation of the proposed approach is also desirable from an ethical viewpoint. Copyright © 2012 John Wiley & Sons, Ltd.

  14. Trainning of Special Education Teachers about Curriculum Development

    ERIC Educational Resources Information Center

    Ozcan, Deniz; Uzunboylu, Huseyin

    2015-01-01

    The aim of this study is to determine the needs of special education teachers about curriculum development, and to implement the constructivist approach to in-service training programme for special education teachers. Furthermore, this study seeks to evaluate the developed in-service training programme. The descriptive and experimental methods…

  15. The Program of Special Directed Studies: A Five Year Summary.

    ERIC Educational Resources Information Center

    Mornell, Eugene S.

    The report described one relatively small but extensively researched special admission and compensatory education program at The Claremont Colleges, California. The Program of Special Directed Studies for Transition to College (PSDS) was administered by the Claremont University Center. PSDS was a 5-year experimental project primarily funded by the…

  16. 15 CFR 744.12 - Restrictions on exports and reexports to persons designated in or pursuant to Executive Order...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... to persons designated in or pursuant to Executive Order 13224 (Specially Designated Global Terrorist... persons designated in or pursuant to Executive Order 13224 (Specially Designated Global Terrorist) (SDGT... part 594, the Global Terrorism Sanctions Regulations. OFAC announces the names of persons designated...

  17. 15 CFR 744.12 - Restrictions on exports and reexports to persons designated in or pursuant to Executive Order...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... to persons designated in or pursuant to Executive Order 13224 (Specially Designated Global Terrorist... persons designated in or pursuant to Executive Order 13224 (Specially Designated Global Terrorist) (SDGT... part 594, the Global Terrorism Sanctions Regulations. OFAC announces the names of persons designated...

  18. 15 CFR 744.12 - Restrictions on exports and reexports to persons designated in or pursuant to Executive Order...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... to persons designated in or pursuant to Executive Order 13224 (Specially Designated Global Terrorist... persons designated in or pursuant to Executive Order 13224 (Specially Designated Global Terrorist) (SDGT... part 594, the Global Terrorism Sanctions Regulations. OFAC announces the names of persons designated...

  19. 15 CFR 744.12 - Restrictions on exports and reexports to persons designated in or pursuant to Executive Order...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... to persons designated in or pursuant to Executive Order 13224 (Specially Designated Global Terrorist... persons designated in or pursuant to Executive Order 13224 (Specially Designated Global Terrorist) (SDGT... part 594, the Global Terrorism Sanctions Regulations. OFAC announces the names of persons designated...

  20. A Design Methodology for Rapid Implementation of Active Control Systems Across Lean Direct Injection Combustor Platforms

    NASA Technical Reports Server (NTRS)

    Baumann, William T.; Saunders, William R.; Vandsburger, Uri; Saus, Joseph (Technical Monitor)

    2003-01-01

    The VACCG team is comprised of engineers at Virginia Tech who specialize in the subject areas of combustion physics, chemical kinetics, dynamics and controls, and signal processing. Currently, the team's work on this NRA research grant is designed to determine key factors that influence combustion control performance through a blend of theoretical and experimental investigations targeting design and demonstration of active control for three different combustors. To validiate the accuracy of conclusions about control effectiveness, a sequence of experimental verifications on increasingly complex lean, direct injection combustors is underway. During the work period January 1, 2002 through October 15, 2002, work has focused on two different laboratory-scale combustors that allow access for a wide variety of measurements. As the grant work proceeds, one key goal will be to obtain certain knowledge about a particular combustor process using a minimum of sophisticated measurements, due to the practical limitations of measurements on full-scale combustors. In the second year, results obtained in the first year will be validated on test combustors to be identified in the first quarter of that year. In the third year, it is proposed to validate the results at more realistic pressure and power levels by utilizing the facilities at the Glenn Research Center.

  1. Do You Want to Make a Difference in the Lives of Students with Special Needs? Careers in Special Education and Related Services.

    ERIC Educational Resources Information Center

    National Clearinghouse for Professions in Special Education, Reston, VA.

    Designed for high school students interested in careers in special education and related services, this guide outlines the different roles of special education and related services professionals who teach and provide specifically designed instruction and services to children with disabilities. It addresses the different disabilities that students…

  2. 15 CFR 744.12 - Restrictions on exports and reexports to persons designated in or pursuant to Executive Order...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... to persons designated in or pursuant to Executive Order 13224 (Specially Designated Global Terrorist... Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION... persons designated in or pursuant to Executive Order 13224 (Specially Designated Global Terrorist) (SDGT...

  3. 31 CFR 536.408 - Alleged change in ownership or control of an entity designated as a specially designated...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... sale of the entity to its new owners. (b) Any continuing substantial financial obligations on the part... to or other enrichment of a specially designated narcotics trafficker could lead to designation of...

  4. Nonlinear Reduced-Order Simulation Using An Experimentally Guided Modal Basis

    NASA Technical Reports Server (NTRS)

    Rizzi, Stephen A.; Przekop, Adam

    2012-01-01

    A procedure is developed for using nonlinear experimental response data to guide the modal basis selection in a nonlinear reduced-order simulation. The procedure entails using nonlinear acceleration response data to first identify proper orthogonal modes. Special consideration is given to cases in which some of the desired response data is unavailable. Bases consisting of linear normal modes are then selected to best represent the experimentally determined transverse proper orthogonal modes and either experimentally determined inplane proper orthogonal modes or the special case of numerically computed in-plane companions. The bases are subsequently used in nonlinear modal reduction and dynamic response simulations. The experimental data used in this work is simulated to allow some practical considerations, such as the availability of in-plane response data and non-idealized test conditions, to be explored. Comparisons of the nonlinear reduced-order simulations are made with the surrogate experimental data to demonstrate the effectiveness of the approach.

  5. Design and assessment of compact optical systems towards special effects imaging

    NASA Astrophysics Data System (ADS)

    Shaoulov, Vesselin Iossifov

    A main challenge in the field of special effects is to create special effects in real time in a way that the user can preview the effect before taking the actual picture or movie sequence. There are many techniques currently used to create computer-simulated special effects, however current techniques in computer graphics do not provide the option for the creation of real-time texture synthesis. Thus, while computer graphics is a powerful tool in the field of special effects, it is neither portable nor does it provide work in real-time capabilities. Real-time special effects may, however, be created optically. Such approach will provide not only real-time image processing at the speed of light but also a preview option, allowing the user or the artist to preview the effect on various parts of the object in order to optimize the outcome. The work presented in this dissertation was inspired by the idea of optically created special effects, such as painterly effects, encoded in images captured by photographic or motion picture cameras. As part of the presented work, compact relay optics was assessed, developed, and a working prototype was built. It was concluded that even though compact relay optics can be achieved, further push for compactness and cost-effectiveness was impossible in the paradigm of bulk macro-optics systems. Thus, a paradigm for imaging with multi-aperture micro-optics was proposed and demonstrated for the first time, which constitutes one of the key contributions of this work. This new paradigm was further extended to the most general case of magnifying multi-aperture micro-optical systems. Such paradigm allows an extreme reduction in size of the imaging optics by a factor of about 10 and a reduction in weight by a factor of about 500. Furthermore, an experimental quantification of the feasibility of optically created special effects was completed, and consequently raytracing software was developed, which was later commercialized by SmARTLens(TM). While the art forms created via raytracing were powerful, they did not predict all effects acquired experimentally. Thus, finally, as key contribution of this work, the principles of scalar diffraction theory were applied to optical imaging of extended objects under quasi-monochromatic incoherent illumination in order to provide a path to more accurately model the proposed optical imaging process for special effects obtained in the hardware. The existing theoretical framework was generalized to non-paraxial in- and out-of-focus imaging and results were obtained to verify the generalized framework. In the generalized non-paraxial framework, even the most complex linear systems, without any assumptions for shift invariance, can be modeled and analyzed.

  6. Design and Implementation of an Innovative Residential PV System

    NASA Astrophysics Data System (ADS)

    Najm, Elie Michel

    This work focuses on the design and implementation of an innovative residential PV system. In chapter one, after an introduction related to the rapid growth of solar systems' installations, the most commonly used state of the art solar power electronics' configurations are discussed, which leads to introducing the proposed DC/DC parallel configuration. The advantages and disadvantages of each of the power electronics' configurations are deliberated. The scope of work in the power electronics is defined in this chapter to be related to the panel side DC/DC converter. System integration and mechanical proposals are also within the scope of work and are discussed in later chapters. Operation principle of a novel low cost PV converter is proposed in chapter 2. The proposal is based on an innovative, simplified analog implementation of a master/slave methodology resulting in an efficient, soft-switched interleaved variable frequency flybacks, operating in the boundary conduction mode (BCM). The scheme concept and circuit configuration, operation principle and theoretical waveforms, design equations, and design considerations are presented. Furthermore, design examples are also given, illustrating the significance of the newly derived frequency equation for flybacks operating in BCM. In chapters 3, 4, and 5, the design implementation and optimization of the novel DC/DC converter illustrated in chapter 2 are discussed. In chapter 3, a detailed variable frequency BCM flyback design model leading to optimizing the component selections and transformer design, detailed in chapter 4, is presented. Furthermore, in chapter 4, the method enabling the use of lower voltage rating switching devices is also discussed. In chapter 5, circuitry related to Start-UP, drive for the main switching devices, zero-voltage-switching (ZVS) as well as turn OFF soft switching and interleaving control are fully detailed. The experimental results of the proposed DC/DC converter are presented in chapter 6. In chapter 7, a novel integration method is proposed for the residential PV solar system. The proposal presents solutions to challenges experimented in the implementation of today's approaches. Faster installation time, easier system grounding, and integration of the power electronics in order to reduce the number of connectors' and system cost are detailed. Installers with special skills as well as special tools are not required for implementing the proposed system integration. Photos of the experimental results related to the installation of a 3kW system, which was fully completed in less than an hour and a half, are also presented.

  7. 14 CFR 91.319 - Aircraft having experimental certificates: Operating limitations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Aircraft having experimental certificates... RULES Special Flight Operations § 91.319 Aircraft having experimental certificates: Operating limitations. (a) No person may operate an aircraft that has an experimental certificate— (1) For other than...

  8. 14 CFR 91.319 - Aircraft having experimental certificates: Operating limitations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Aircraft having experimental certificates... RULES Special Flight Operations § 91.319 Aircraft having experimental certificates: Operating limitations. (a) No person may operate an aircraft that has an experimental certificate— (1) For other than...

  9. 14 CFR 91.319 - Aircraft having experimental certificates: Operating limitations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Aircraft having experimental certificates... RULES Special Flight Operations § 91.319 Aircraft having experimental certificates: Operating limitations. (a) No person may operate an aircraft that has an experimental certificate— (1) For other than...

  10. 14 CFR 91.319 - Aircraft having experimental certificates: Operating limitations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Aircraft having experimental certificates... RULES Special Flight Operations § 91.319 Aircraft having experimental certificates: Operating limitations. (a) No person may operate an aircraft that has an experimental certificate— (1) For other than...

  11. 14 CFR 91.319 - Aircraft having experimental certificates: Operating limitations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Aircraft having experimental certificates... RULES Special Flight Operations § 91.319 Aircraft having experimental certificates: Operating limitations. (a) No person may operate an aircraft that has an experimental certificate— (1) For other than...

  12. Computational Redesign of Thioredoxin Is Hypersensitive toward Minor Conformational Changes in the Backbone Template

    PubMed Central

    Christensen, Signe; Horowitz, Scott; Bardwell, James C.A.; Olsen, Johan G.; Willemoës, Martin; Lindorff-Larsen, Kresten; Ferkinghoff-Borg, Jesper; Hamelryck, Thomas; Winther, Jakob R.

    2017-01-01

    Despite the development of powerful computational tools, the full-sequence design of proteins still remains a challenging task. To investigate the limits and capabilities of computational tools, we conducted a study of the ability of the program Rosetta to predict sequences that recreate the authentic fold of thioredoxin. Focusing on the influence of conformational details in the template structures, we based our study on 8 experimentally determined template structures and generated 120 designs from each. For experimental evaluation, we chose six sequences from each of the eight templates by objective criteria. The 48 selected sequences were evaluated based on their progressive ability to (1) produce soluble protein in Escherichia coli and (2) yield stable monomeric protein, and (3) on the ability of the stable, soluble proteins to adopt the target fold. Of the 48 designs, we were able to synthesize 32, 20 of which resulted in soluble protein. Of these, only two were sufficiently stable to be purified. An X-ray crystal structure was solved for one of the designs, revealing a close resemblance to the target structure. We found a significant difference among the eight template structures to realize the above three criteria despite their high structural similarity. Thus, in order to improve the success rate of computational full-sequence design methods, we recommend that multiple template structures are used. Furthermore, this study shows that special care should be taken when optimizing the geometry of a structure prior to computational design when using a method that is based on rigid conformations. PMID:27659562

  13. Computational Redesign of Thioredoxin Is Hypersensitive toward Minor Conformational Changes in the Backbone Template.

    PubMed

    Johansson, Kristoffer E; Tidemand Johansen, Nicolai; Christensen, Signe; Horowitz, Scott; Bardwell, James C A; Olsen, Johan G; Willemoës, Martin; Lindorff-Larsen, Kresten; Ferkinghoff-Borg, Jesper; Hamelryck, Thomas; Winther, Jakob R

    2016-10-23

    Despite the development of powerful computational tools, the full-sequence design of proteins still remains a challenging task. To investigate the limits and capabilities of computational tools, we conducted a study of the ability of the program Rosetta to predict sequences that recreate the authentic fold of thioredoxin. Focusing on the influence of conformational details in the template structures, we based our study on 8 experimentally determined template structures and generated 120 designs from each. For experimental evaluation, we chose six sequences from each of the eight templates by objective criteria. The 48 selected sequences were evaluated based on their progressive ability to (1) produce soluble protein in Escherichia coli and (2) yield stable monomeric protein, and (3) on the ability of the stable, soluble proteins to adopt the target fold. Of the 48 designs, we were able to synthesize 32, 20 of which resulted in soluble protein. Of these, only two were sufficiently stable to be purified. An X-ray crystal structure was solved for one of the designs, revealing a close resemblance to the target structure. We found a significant difference among the eight template structures to realize the above three criteria despite their high structural similarity. Thus, in order to improve the success rate of computational full-sequence design methods, we recommend that multiple template structures are used. Furthermore, this study shows that special care should be taken when optimizing the geometry of a structure prior to computational design when using a method that is based on rigid conformations. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Functional Specialization of the Cerebral Hemispheres in Infants and Children: New Experimental and Clinical Evidence.

    ERIC Educational Resources Information Center

    Harris, Lauren Jay

    This paper presents background information, an introductory statement of theoretical positions, and brief abstracts of research papers from a symposium on the functional specialization of cerebral hemispheres in infants and children. According to one view of the development of cerebral specialization, the two hemispheres are initially…

  15. Web buckling behavior under in-plane compression and shear loads for web reinforced composite sandwich core

    NASA Astrophysics Data System (ADS)

    Toubia, Elias Anis

    Sandwich construction is one of the most functional forms of composite structures developed by the composite industry. Due to the increasing demand of web-reinforced core for composite sandwich construction, a research study is needed to investigate the web plate instability under shear, compression, and combined loading. If the web, which is an integral part of the three dimensional web core sandwich structure, happens to be slender with respect to one or two of its spatial dimensions, then buckling phenomena become an issue in that it must be quantified as part of a comprehensive strength model for a fiber reinforced core. In order to understand the thresholds of thickness, web weight, foam type, and whether buckling will occur before material yielding, a thorough investigation needs to be conducted, and buckling design equations need to be developed. Often in conducting a parametric study, a special purpose analysis is preferred over a general purpose analysis code, such as a finite element code, due to the cost and effort usually involved in generating a large number of results. A suitable methodology based on an energy method is presented to solve the stability of symmetrical and specially orthotropic laminated plates on an elastic foundation. Design buckling equations were developed for the web modeled as a laminated plate resting on elastic foundations. The proposed equations allow for parametric studies without limitation regarding foam stiffness, geometric dimensions, or mechanical properties. General behavioral trends of orthotropic and symmetrical anisotropic plates show pronounced contribution of the elastic foundation and fiber orientations on the buckling resistance of the plate. The effects of flexural anisotropy on the buckling behavior of long rectangular plates when subjected to pure shear loading are well represented in the model. The reliability of the buckling equations as a design tool is confirmed by comparison with experimental results. Comparing to predicted values, the experimental plate shear test results range between 15 and 35 percent, depending on the boundary conditions considered. The compression testing yielded conservative results, and as such, can provide a valuable tool for the designer.

  16. Wellbore Completion Systems Containment Breach Solution Experiments at a Large Scale Underground Research Laboratory : Sealant placement & scale-up from Lab to Field

    NASA Astrophysics Data System (ADS)

    Goodman, H.

    2017-12-01

    This investigation seeks to develop sealant technology that can restore containment to completed wells that suffer CO2 gas leakages currently untreatable using conventional technologies. Experimentation is performed at the Mont Terri Underground Research Laboratory (MT-URL) located in NW Switzerland. The laboratory affords investigators an intermediate-scale test site that bridges the gap between the laboratory bench and full field-scale conditions. Project focus is the development of CO2 leakage remediation capability using sealant technology. The experimental concept includes design and installation of a field scale completion package designed to mimic well systems heating-cooling conditions that may result in the development of micro-annuli detachments between the casing-cement-formation boundaries (Figure 1). Of particular interest is to test novel sealants that can be injected in to relatively narrow micro-annuli flow-paths of less than 120 microns aperture. Per a special report on CO2 storage submitted to the IPCC[1], active injection wells, along with inactive wells that have been abandoned, are identified as one of the most probable sources of leakage pathways for CO2 escape to the surface. Origins of pressure leakage common to injection well and completions architecture often occur due to tensile cracking from temperature cycles, micro-annulus by casing contraction (differential casing to cement sheath movement) and cement sheath channel development. This discussion summarizes the experiment capability and sealant testing results. The experiment concludes with overcoring of the entire mock-completion test site to assess sealant performance in 2018. [1] IPCC Special Report on Carbon Dioxide Capture and Storage (September 2005), section 5.7.2 Processes and pathways for release of CO2 from geological storage sites, page 244

  17. Adaptive identification of vessel's added moments of inertia with program motion

    NASA Astrophysics Data System (ADS)

    Alyshev, A. S.; Melnikov, V. G.

    2018-05-01

    In this paper, we propose a new experimental method for determining the moments of inertia of the ship model. The paper gives a brief review of existing methods, a description of the proposed method and experimental stand, test procedures and calculation formulas and experimental results. The proposed method is based on the energy approach with special program motions. The ship model is fixed in a special rack consisting of a torsion element and a set of additional servo drives with flywheels (reactive wheels), which correct the motion. The servo drives with an adaptive controller provide the symmetry of the motion, which is necessary for the proposed identification procedure. The effectiveness of the proposed approach is confirmed by experimental results.

  18. 31 CFR 598.408 - Alleged change in ownership or control of an entity designated as a specially designated...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... of an entity designated as a specially designated narcotics trafficker. 598.408 Section 598.408 Money... CONTROL, DEPARTMENT OF THE TREASURY FOREIGN NARCOTICS KINGPIN SANCTIONS REGULATIONS Interpretations § 598... the entity no longer meets the criteria for designation under § 598.314. Evidence submitted must...

  19. 31 CFR 598.408 - Alleged change in ownership or control of an entity designated as a specially designated...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... of an entity designated as a specially designated narcotics trafficker. 598.408 Section 598.408 Money... CONTROL, DEPARTMENT OF THE TREASURY FOREIGN NARCOTICS KINGPIN SANCTIONS REGULATIONS Interpretations § 598... the entity no longer meets the criteria for designation under § 598.314. Evidence submitted must...

  20. 31 CFR 598.408 - Alleged change in ownership or control of an entity designated as a specially designated...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of an entity designated as a specially designated narcotics trafficker. 598.408 Section 598.408 Money... CONTROL, DEPARTMENT OF THE TREASURY FOREIGN NARCOTICS KINGPIN SANCTIONS REGULATIONS Interpretations § 598... the entity no longer meets the criteria for designation under § 598.314. Evidence submitted must...

  1. 31 CFR 598.408 - Alleged change in ownership or control of an entity designated as a specially designated...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of an entity designated as a specially designated narcotics trafficker. 598.408 Section 598.408 Money... CONTROL, DEPARTMENT OF THE TREASURY FOREIGN NARCOTICS KINGPIN SANCTIONS REGULATIONS Interpretations § 598... the entity no longer meets the criteria for designation under § 598.314. Evidence submitted must...

  2. Evaluation of actuators for the SDOF and MDOF active microgravity isolation systems

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The University of Virginia examined the design of actuators for both single-degree-of-freedom (SDOF) and multiple-degree-of-freedom (MDOF) active microgravity isolation systems. For SDOF systems, two actuators were considered: a special large gap magnetic actuator and a large stroke Lorentz actuator. The magnetic actuator was viewed to be of greater difficulty than the Lorentz actuator with little compelling technical advantage and was dropped from consideration. A Lorentz actuator was designed and built for the SDOF test rig using magnetic circuit and finite element analysis. The design and some experimental results are discussed. The University also examined the design of actuators for MDOF isolation systems. This includes design of an integrated 1 cm gap 6-DOF noncontacting magnetic suspension system and of a 'coarse' follower which permits the practical extension of magnetic suspension to large strokes. The proposed 'coarse' actuator was a closed kinematic chain manipulator known as a Stewart Platform. The integration of the two isolation systems together, the isolation tasks assigned to each, and possible control architectures were also explored. The results of this research are examined.

  3. 24 CFR 3285.315 - Special snow load conditions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... HOUSING AND URBAN DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Foundations § 3285.315 Special snow load conditions. (a) General. Foundations for homes designed for and located in areas with roof live loads greater than 40 psf must be designed by the manufacturer for the special snow load...

  4. 34 CFR 387.1 - What is the Experimental and Innovative Training Program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true What is the Experimental and Innovative Training Program...) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EXPERIMENTAL AND INNOVATIVE TRAINING General § 387.1 What is the Experimental and Innovative Training Program? This program is...

  5. 34 CFR 387.1 - What is the Experimental and Innovative Training Program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true What is the Experimental and Innovative Training Program...) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EXPERIMENTAL AND INNOVATIVE TRAINING General § 387.1 What is the Experimental and Innovative Training Program? This program is...

  6. 34 CFR 387.1 - What is the Experimental and Innovative Training Program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What is the Experimental and Innovative Training... (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EXPERIMENTAL AND INNOVATIVE TRAINING General § 387.1 What is the Experimental and Innovative Training Program? This program is...

  7. 34 CFR 387.1 - What is the Experimental and Innovative Training Program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false What is the Experimental and Innovative Training... (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EXPERIMENTAL AND INNOVATIVE TRAINING General § 387.1 What is the Experimental and Innovative Training Program? This program is...

  8. 34 CFR 387.1 - What is the Experimental and Innovative Training Program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false What is the Experimental and Innovative Training... (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EXPERIMENTAL AND INNOVATIVE TRAINING General § 387.1 What is the Experimental and Innovative Training Program? This program is...

  9. 26 CFR 1.861-17 - Allocation and apportionment of research and experimental expenditures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of the group has changed methods. (f) Special rules for partnerships—(1) Research and experimental... and Wiring Equipment (SIC Industry Group 364). Thus, X's research and experimental expenses are... experimental expenditures. 1.861-17 Section 1.861-17 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF...

  10. 26 CFR 1.861-17 - Allocation and apportionment of research and experimental expenditures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... of the group has changed methods. (f) Special rules for partnerships—(1) Research and experimental... and Wiring Equipment (SIC Industry Group 364). Thus, X's research and experimental expenses are... experimental expenditures. 1.861-17 Section 1.861-17 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF...

  11. 26 CFR 1.861-17 - Allocation and apportionment of research and experimental expenditures.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... of the group has changed methods. (f) Special rules for partnerships—(1) Research and experimental... and Wiring Equipment (SIC Industry Group 364). Thus, X's research and experimental expenses are... experimental expenditures. 1.861-17 Section 1.861-17 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF...

  12. 26 CFR 1.861-17 - Allocation and apportionment of research and experimental expenditures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of the group has changed methods. (f) Special rules for partnerships—(1) Research and experimental... and Wiring Equipment (SIC Industry Group 364). Thus, X's research and experimental expenses are... experimental expenditures. 1.861-17 Section 1.861-17 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF...

  13. 26 CFR 1.861-17 - Allocation and apportionment of research and experimental expenditures.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... of the group has changed methods. (f) Special rules for partnerships—(1) Research and experimental... and Wiring Equipment (SIC Industry Group 364). Thus, X's research and experimental expenses are... experimental expenditures. 1.861-17 Section 1.861-17 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF...

  14. Understanding the Effect of Grain Boundary Character on Dynamic Recrystallization in Stainless Steel 316L

    NASA Astrophysics Data System (ADS)

    Beck, Megan; Morse, Michael; Corolewski, Caleb; Fritchman, Koyuki; Stifter, Chris; Poole, Callum; Hurley, Michael; Frary, Megan

    2017-08-01

    Dynamic recrystallization (DRX) occurs during high-temperature deformation in metals and alloys with low to medium stacking fault energies. Previous simulations and experimental research have shown the effect of temperature and grain size on DRX behavior, but not the effect of the grain boundary character distribution. To investigate the effects of the distribution of grain boundary types, experimental testing was performed on stainless steel 316L specimens with different initial special boundary fractions (SBF). This work was completed in conjunction with computer simulations that used a modified Monte Carlo method which allowed for the addition of anisotropic grain boundary energies using orientation data from electron backscatter diffraction (EBSD). The correlation of the experimental and simulation work allows for a better understanding of how the input parameters in the simulations correspond to what occurs experimentally. Results from both simulations and experiments showed that a higher fraction of so-called "special" boundaries ( e.g., Σ3 twin boundaries) delayed the onset of recrystallization to larger strains and that it is energetically favorable for nuclei to form on triple junctions without these so-called "special" boundaries.

  15. 10 CFR 170.21 - Schedule of fees for production and utilization facilities, review of standard referenced design...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., review of standard referenced design approvals, special projects, inspections and import and export... standard referenced design approvals, special projects, inspections and import and export licenses..., approvals of facility standard reference designs, re-qualification and replacement examinations for reactor...

  16. 10 CFR 170.21 - Schedule of fees for production and utilization facilities, review of standard referenced design...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., review of standard referenced design approvals, special projects, inspections and import and export... standard referenced design approvals, special projects, inspections and import and export licenses..., approvals of facility standard reference designs, re-qualification and replacement examinations for reactor...

  17. 10 CFR 170.21 - Schedule of fees for production and utilization facilities, review of standard referenced design...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., review of standard referenced design approvals, special projects, inspections and import and export... standard referenced design approvals, special projects, inspections and import and export licenses..., approvals of facility standard reference designs, re-qualification and replacement examinations for reactor...

  18. 10 CFR 170.21 - Schedule of fees for production and utilization facilities, review of standard referenced design...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., review of standard referenced design approvals, special projects, inspections and import and export... standard referenced design approvals, special projects, inspections and import and export licenses..., approvals of facility standard reference designs, re-qualification and replacement examinations for reactor...

  19. Comparative Markedness and Induced Opacity*

    PubMed Central

    Dinnsen, Daniel A.; Gierut, Judith A.; Farris-Trimble, Ashley W.

    2011-01-01

    Results are reported from a descriptive and experimental study that was intended to evaluate comparative markedness (McCarthy 2002, 2003) as an amendment to optimality theory. Two children (aged 4;3 and 4;11) with strikingly similar, delayed phonologies presented with two independent, interacting error patterns of special interest, i.e., Deaffrication ([tɪn] ‘chin’) and Consonant Harmony ([ɡɔɡ] ‘dog’) in a feeding interaction ([kik] ‘cheek’). Both children were enrolled in a counterbalanced treatment study employing a multiple base-line single-subject experimental design, which was intended to induce a grandfather effect in one case ([dɔɡ] ‘dog’ and [kik] ‘cheek’) and a counterfeeding interaction in the other ([ɡɔɡ] ‘dog’ and [tik] ‘cheek’). The results were largely supportive of comparative markedness, although some anomalies were observed. The clinical implications of these results are also explored. PMID:21666872

  20. Experimental investigation and performance analysis of six low flow coefficient centrifugal compressor stages

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Paroubek, J.; Cyrus, V.; Kyncl, J.

    1995-10-01

    Some results of a research and development program for centrifugal compressors are presented. Six-stage configurations with low flow coefficient were tested. The stages had channel width parameter b{sub 2}/D{sub 2} = 0.01 and 0.03. For each value of the width parameter, three different impellers with inlet hub to outlet diameter ratio d{sub 0}/D{sub 2} = 0.3, 0.4, and 0.5 were designed. Test rig, instrumentation, and data analysis are described. Special attention was devoted to probe calibrations and to evaluation of the leakage, bearing, and disk friction losses. Aerodynamic performance of all tested stages is presented. Slip factors of impellers obtainedmore » experimentally and theoretically are compared. Losses in both vaneless diffuser and return channel with deswirl vanes are discussed. Rotating stall was also investigated. Criteria for stall limit were tested.« less

  1. Digital image compression for a 2f multiplexing optical setup

    NASA Astrophysics Data System (ADS)

    Vargas, J.; Amaya, D.; Rueda, E.

    2016-07-01

    In this work a virtual 2f multiplexing system was implemented in combination with digital image compression techniques and redundant information elimination. Depending on the image type to be multiplexed, a memory-usage saving of as much as 99% was obtained. The feasibility of the system was tested using three types of images, binary characters, QR codes, and grey level images. A multiplexing step was implemented digitally, while a demultiplexing step was implemented in a virtual 2f optical setup following real experimental parameters. To avoid cross-talk noise, each image was codified with a specially designed phase diffraction carrier that would allow the separation and relocation of the multiplexed images on the observation plane by simple light propagation. A description of the system is presented together with simulations that corroborate the method. The present work may allow future experimental implementations that will make use of all the parallel processing capabilities of optical systems.

  2. [3D-TV health assessment system by the multi-modal physiological signals].

    PubMed

    Li, Zhongqiang; Xing, Lidong; Qian, Zhiyu; Wang, Xiao; Yu, Defei; Liu, Baoyu; Jin, Shuai

    2014-03-01

    In order to meet the requirements of the multi-physiological signal measurement of the 3D-TV health assessment, try to find the suitable biological acquisition chips and design the hardware system which can detect different physiological signals in real time. The systems mainly uses ARM11/S3C6410 microcontroller to control the EEG/EOG acquisition chip RHA2116 and the ECG acquisition chip ADS1298, and then the microcontroller transfer the data collected by the chips to the PC software by the USB port which can display and save the experimental data in real time, then use the Matlab software for further processing of the data, finally make a final health assessment. In the meantime, for the different varieties in the different brain regions of watching 3D-TV, developed the special brain electrode placement and the experimental data processing methods, then effectively disposed the multi-signal data in the multilevel.

  3. A high efficiency coaxial pulse tube cryocooler operating at 60 K

    NASA Astrophysics Data System (ADS)

    Wang, Nailiang; Zhao, Miguang; Ou, Yangyang; Zhu, Qianglong; Wei, Lingjiao; Chen, Houlei; Cai, Jinghui; Liang, Jingtao

    2018-07-01

    In recent years, improved efficiency of pulse tube cryocoolers has been required by some space infrared detectors and special military applications. Based on this, a high efficiency single-stage coaxial pulse tube cryocooler which operates at 60 K is introduced in this paper. The cryocooler is numerically designed using SAGE, and details of the analysis are presented. The performance of the cryocooler at different input powers ranging from 100 W to 200 W is experimentally tested. Experimental results show that this cryocooler typically provides a cooling power of 7.7 W at 60 K with an input power of 200 W, and achieves a relative Carnot efficiency of around 15%. When the cooling power is around 6 W, the cryocooler achieves the best relative Carnot efficiency of around 15.9% at 60 K, which is the highest efficiency ever reported for a coaxial pulse tube cryocooler.

  4. Studies of turbulence models in a computational fluid dynamics model of a blood pump.

    PubMed

    Song, Xinwei; Wood, Houston G; Day, Steven W; Olsen, Don B

    2003-10-01

    Computational fluid dynamics (CFD) is used widely in design of rotary blood pumps. The choice of turbulence model is not obvious and plays an important role on the accuracy of CFD predictions. TASCflow (ANSYS Inc., Canonsburg, PA, U.S.A.) has been used to perform CFD simulations of blood flow in a centrifugal left ventricular assist device; a k-epsilon model with near-wall functions was used in the initial numerical calculation. To improve the simulation, local grids with special distribution to ensure the k-omega model were used. Iterations have been performed to optimize the grid distribution and turbulence modeling and to predict flow performance more accurately comparing to experimental data. A comparison of k-omega model and experimental measurements of the flow field obtained by particle image velocimetry shows better agreement than k-epsilon model does, especially in the near-wall regions.

  5. DNA-bridged Chiroplasmonic Assemblies of Nanoparticles

    NASA Astrophysics Data System (ADS)

    Kotov, Nicholas

    2015-03-01

    Chirality at nanoscale attracts a lot of attention during the last decade. A number of chiral nanoscale systems had been discovered ranging from individual nanoparticles to helical nanowires and from lithographically defined substrates. DNA bridges make possible in-silico engineering and practical construction of complex assemblies of nanoparticles with of both plasmonic and excitonic nature. In this presentation, expected and unexpected optical effects that we observed in chiral plasmonic and excitonic systems will be demonstrated. Special effort will be placed on the transitioning of theoretical and experimental knowledge about chiral nanoscale systems to applications. The most obvious direction for practical targets was so far, the design of metamaterials for negative refractive index optics. The results describing the 3D materials with the highest experimentally observed chiral anisotropy factor will be presented. It will be followed by the discussion of the recent developments in analytical application of chiral assemblies for detection of cancer and bacterial contamination.

  6. Big Ideas in Special Education: Specially Designed Instruction, High-Leverage Practices, Explicit Instruction, and Intensive Instruction

    ERIC Educational Resources Information Center

    Riccomini, Paul J.; Morano, Stephanie; Hughes, Charles A.

    2017-01-01

    It is understandable that misuse of the terms "specially designed instruction" (SDI), "high-leverage practices" (HLPs), "explicit instruction" (EI), and "intensive instruction"(II) has bred confusion among professionals, and this confusion may lead to miscommunication and misunderstandings in the field.…

  7. The Habitability Framework: Linking Human Behavior and Physical Environment in Special Education.

    ERIC Educational Resources Information Center

    Preiser, Wolfgang F. E.; Taylor, Anne

    1983-01-01

    The concept of environmental design cybernetics is explained, and its use by special educators and architects in creating learning environments is discussed. A proposed habitability framework is defined, and its applications to buildings and building occupants/users are offered. Research on architectural design applied to special education…

  8. “No level up!”: no effects of video game specialization and expertise on cognitive performance

    PubMed Central

    Gobet, Fernand; Johnston, Stephen J.; Ferrufino, Gabriella; Johnston, Matthew; Jones, Michael B.; Molyneux, Antonia; Terzis, Argyrios; Weeden, Luke

    2014-01-01

    Previous research into the effects of action video gaming on cognition has suggested that long term exposure to this type of game might lead to an enhancement of cognitive skills that transfer to non-gaming cognitive tasks. However, these results have been controversial. The aim of the current study was to test the presence of positive cognitive transfer from action video games to two cognitive tasks. More specifically, this study investigated the effects that participants' expertise and genre specialization have on cognitive improvements in one task unrelated to video gaming (a flanker task) and one related task (change detection task with both control and genre-specific images). This study was unique in three ways. Firstly, it analyzed a continuum of expertise levels, which has yet to be investigated in research into the cognitive benefits of video gaming. Secondly, it explored genre-specific skill developments on these tasks by comparing Action and Strategy video game players (VGPs). Thirdly, it used a very tight experiment design, including the experimenter being blind to expertise level and genre specialization of the participant. Ninety-two university students aged between 18 and 30 (M = 21.25) were recruited through opportunistic sampling and were grouped by video game specialization and expertise level. While the results of the flanker task were consistent with previous research (i.e., effect of congruence), there was no effect of expertise, and the action gamers failed to outperform the strategy gamers. Additionally, contrary to expectation, there was no interaction between genre specialization and image type in the change detection task, again demonstrating no expertise effect. The lack of effects for game specialization and expertise goes against previous research on the positive effects of action video gaming on other cognitive tasks. PMID:25506330

  9. "No level up!": no effects of video game specialization and expertise on cognitive performance.

    PubMed

    Gobet, Fernand; Johnston, Stephen J; Ferrufino, Gabriella; Johnston, Matthew; Jones, Michael B; Molyneux, Antonia; Terzis, Argyrios; Weeden, Luke

    2014-01-01

    Previous research into the effects of action video gaming on cognition has suggested that long term exposure to this type of game might lead to an enhancement of cognitive skills that transfer to non-gaming cognitive tasks. However, these results have been controversial. The aim of the current study was to test the presence of positive cognitive transfer from action video games to two cognitive tasks. More specifically, this study investigated the effects that participants' expertise and genre specialization have on cognitive improvements in one task unrelated to video gaming (a flanker task) and one related task (change detection task with both control and genre-specific images). This study was unique in three ways. Firstly, it analyzed a continuum of expertise levels, which has yet to be investigated in research into the cognitive benefits of video gaming. Secondly, it explored genre-specific skill developments on these tasks by comparing Action and Strategy video game players (VGPs). Thirdly, it used a very tight experiment design, including the experimenter being blind to expertise level and genre specialization of the participant. Ninety-two university students aged between 18 and 30 (M = 21.25) were recruited through opportunistic sampling and were grouped by video game specialization and expertise level. While the results of the flanker task were consistent with previous research (i.e., effect of congruence), there was no effect of expertise, and the action gamers failed to outperform the strategy gamers. Additionally, contrary to expectation, there was no interaction between genre specialization and image type in the change detection task, again demonstrating no expertise effect. The lack of effects for game specialization and expertise goes against previous research on the positive effects of action video gaming on other cognitive tasks.

  10. Capitalizing on Community: the Small College Environment and the Development of Researchers

    NASA Astrophysics Data System (ADS)

    Stoneking, M. R.

    2014-03-01

    Liberal arts colleges constitute an important source of and training ground for future scientists. At Lawrence University, we take advantage of our small college environment to prepare physics students for research careers by complementing content acquisition with skill development and project experience distributed throughout the curriculum and with co-curricular elements that are tied to our close-knit supportive physics community. Small classes and frequent contact between physics majors and faculty members offer opportunities for regular and detailed feedback on the development of research relevant skills such as laboratory record-keeping, data analysis, electronic circuit design, computational programming, experimental design and modification, and scientific communication. Part of our approach is to balance collaborative group work on small projects (such as Arduino-based electronics projects and optical design challenges) with independent work (on, for example, advanced laboratory experimental extensions and senior capstone projects). Communal spaces and specialized facilities (experimental and computational) and active on-campus research programs attract eager students to the program, establish a community-based atmosphere, provide unique opportunities for the development of research aptitude, and offer opportunities for genuine contribution to a research program. Recently, we have also been encouraging innovativetendencies in physics majors through intentional efforts to develop personal characteristics, encouraging students to become more tolerant of ambiguity, risk-taking, initiative-seeking, and articulate. Indicators of the success of our approach include the roughly ten physics majors who graduate each year and our program's high ranking among institutions whose graduates go on to receive the Ph.D. in physics. Work supported in part by the National Science Foundation.

  11. End wall flow characteristics and overall performance of an axial flow compressor stage

    NASA Technical Reports Server (NTRS)

    Sitaram, N.; Lakshminarayana, B.

    1983-01-01

    This review indicates the possible future directions for research on endwall flows in axial flow compressors. Theoretical investigations on the rotor blade endwall flows in axial flow compressors reported here include the secondary flow calculation and the development of the momentum integral equations for the prediction of the annulus wall boundary layer. The equations for secondary vorticity at the rotor exit are solved analytically. The solution includes the effects of rotation and the viscosity. The momentum integral equations derived include the effect of the blade boundary layers. The axial flow compressor facility of the Department of Aerospace Engineering at The Pennsylvania State University, which is used for the experimental investigations of the endwall flows, is described in some detail. The overall performance and other preliminary experimental results are presented. Extensive radial flow surveys are carried out at the design and various off design conditions. These are presented and interpreted in this report. The following experimental investigations of the blade endwall flows are carried out. (1) Rotor blade endwall flows: The following measurements are carried out at four flow coefficients. (a) The rotor blade static pressures at various axial and radial stations (with special emphasis near the blade tips). (b) The hub wall static pressures inside the rotor blade passage at various axial and tangential stations. (2) IGV endwall flows: The following measurements are carried out at the design flow coefficient. (a) The boundary layer profiles at various axial and tangential stations inside the blade passage and at the blade exit. (b) Casing static pressures and limiting streamline angles inside the blade passage.

  12. 50 CFR 17.84 - Special rules-vertebrates.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... WILDLIFE AND PLANTS (CONTINUED) ENDANGERED AND THREATENED WILDLIFE AND PLANTS Experimental Populations § 17... experimental population. (2) No person shall take this species, except: (i) For educational purposes... section, are experimental, nonessential populations. (2) No person shall take the species, except in...

  13. 50 CFR 17.84 - Special rules-vertebrates.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... WILDLIFE AND PLANTS (CONTINUED) ENDANGERED AND THREATENED WILDLIFE AND PLANTS Experimental Populations § 17... experimental population. (2) No person shall take this species, except: (i) For educational purposes... section, are experimental, nonessential populations. (2) No person shall take the species, except in...

  14. 50 CFR 17.84 - Special rules-vertebrates.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... WILDLIFE AND PLANTS (CONTINUED) ENDANGERED AND THREATENED WILDLIFE AND PLANTS Experimental Populations § 17... experimental population. (2) No person shall take this species, except: (i) For educational purposes... section, are experimental, nonessential populations. (2) No person shall take the species, except in...

  15. 50 CFR 17.84 - Special rules-vertebrates.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... WILDLIFE AND PLANTS (CONTINUED) ENDANGERED AND THREATENED WILDLIFE AND PLANTS Experimental Populations § 17... experimental population. (2) No person shall take this species, except: (i) For educational purposes... section, are experimental, nonessential populations. (2) No person shall take the species, except in...

  16. Re-Imagining Specialized STEM Academies: Igniting and Nurturing "Decidedly Different Minds", by Design

    ERIC Educational Resources Information Center

    Marshall, Stephanie Pace

    2010-01-01

    This article offers a personal vision and conceptual design for reimagining specialized science, technology, engineering, and mathematics (STEM) academies designed to nurture "decidedly different" STEM minds and ignite a new generation of global STEM talent, innovation, and entrepreneurial leadership. This design enables students to engage…

  17. [Experimental study on a novel esophageal prosthesis made of composite biomaterials].

    PubMed

    Qin, Xiong; Xu, Zhi-fei; Shi, Hong-can; Zhao, Xue-wei; Sun, Kang; Gao, Xiang-yang

    2003-07-01

    To design and develop a novel esophageal prosthesis by selecting appropriate biomaterials, developing special manufacturing techniques, and investigating the feasibility of replacement of cervical esophagus in mongrel dogs. In accordance with the requirements of ideal esophageal substitutes, we designed a new type of esophageal prostheses. The inner stent were made with polyurethane of medical grade, and the outer surface of the prosthesis was coated with collagen-chitosan sponge. The silicone tube was used as a control. Thirteen adult mongrel dogs that were divided into two groups were used to establish the experimental models. In the experimental group (n = 8), the esophageal prostheses were completely incorporated with the native esophagus and adherent to the surrounding host connective tissues. Epithelial linings of varying degrees were formed on the luminal surface, and complete epithelization was seen in 1 month postoperatively. The granulation at the sites of the anastomosis in this group was less significant than that of the control group. One dog has been surviving for 12 months up to now without any complications. In the control group (n = 5), esophageal epithelial was not observed on the luminal surface, constriction of the regenerated esophagus progressed and all the dogs died within 2 months after operation. These observations suggest that this esophageal prosthesis made of composite biomaterials has high biocompatibility and potential for long-segment esophageal reconstruction, which is promising for the clinical repair of esophageal defects.

  18. Update of the equations of the limit state of the structural material with the realization of their deformation

    NASA Astrophysics Data System (ADS)

    Zenkov, E. V.

    2018-01-01

    Two methods are given in the article by considering the type of stressed-Deformed state (SDS) based on equations limit condition and analyzing the results of laboratory tests of special specimens for mechanical testing, focus having destruction thereof in the same view of SDS as in focus possible destruction of the structural member. The considered limited use of these methods in terms of considering physically consistent strength criterion type Pisarenko-Lebedev. A revised design-experimental procedure for determining the strength of the material of the structure, combining therein the elements of these two methods, consisting in determining the strength parameters of construction material, entering criterion equation Pisarenko-Lebedev, considering the actual appearance of the region-of-interest SDS structure. The implementation of the procedure is performed on the basis of the selection of the respective experimental laboratory specimens for mechanical testing, plan SDS in working zone coinciding with a SDS: structure whose strength is evaluated. The refinement process limit state equations demonstrated in determining 50CrV4 steel strength parameters, being in a state of biaxial stretching. Design-experimentally determined by, that steel for a given voltage limit value is almost a quarter of its value is reduced compared to the conventional tensile strength. value is reduced compared to the conventional tensile strength.

  19. Characteristics of capacitance-micro-displacement for model of complex interior surface of the 3D Taiji ball and its applications

    NASA Astrophysics Data System (ADS)

    Zhu, Ruo-Gu; Jiang, Kun; Qing, Zhao-Bo; Liu, Yue-Hui; Yan, Jun

    2006-11-01

    Taiji image originated from ancient China. It is not only the Taoism emblem but also the ancient graphic presentation sign to everything origin. It either has a too far-reaching impact on traditional culture of China, or is influencing the development of current natural science. On the basis of analyzing the classical philosophic theory of two-dimensional (2-D) Taiji image, we developed it into the model of complex interior surface-three-dimensional (3-D) Taiji ball, and explored its possible applications. Combining modern mathematics and physics knowledge, we have studied on the physical meaning of 3-D Taiji ball, thus the plane change of original Taiji image is developed into space change which is more close to the real world. The change layers are obvious increased notably, and the amount of information included in this model increases correspondingly. We also realized a special paper 3-D Taiji ball whose surface is coved with metal foil by means of laser manufacture. A new experiment set-up for measuring micro displace has been designed and constituted thus the relation between capacitance and micro displacement for the 3-D Taiji ball has performed. Experimental and theoretical analyses are also finished. This models of 3-D Taiji ball for physical characteristics are the first time set up. Experimental data and fitting curves between capacitance and micro displacement for the special paper Taiji ball coved with metal foil are suggested. It is shown that the special Taiji ball has less leakage capacitance or more strengthen electric field than an ordinary half ball capacitance. Finally their potential applied values are explored.

  20. Characteristics and application of spherical-type activation detectors in neutron spectrum measurements at a boron neutron capture therapy (BNCT) facility

    NASA Astrophysics Data System (ADS)

    Lin, Heng-Xiao; Chen, Wei-Lin; Liu, Yuan-Hao; Sheu, Rong-Jiun

    2016-03-01

    A set of spherical-type activation detectors was developed aiming to provide better determination of the neutron spectrum at the Tsing Hua Open-pool Reactor (THOR) BNCT facility. An activation foil embedded in a specially designed spherical holder exhibits three advantages: (1) minimizing the effect of neutron angular dependence, (2) creating response functions with broadened coverage of neutron energies by introducing additional moderators or absorbers to the central activation foil, and (3) reducing irradiation time because of improved detection efficiencies to epithermal neutron beam. This paper presents the design concept and the calculated response functions of new detectors. Theoretical and experimental demonstrations of the performance of the detectors are provided through comparisons of the unfolded neutron spectra determined using this method and conventional multiple-foil activation techniques.

  1. Potential of mechanical metamaterials to induce their own global rotational motion

    NASA Astrophysics Data System (ADS)

    Dudek, K. K.; Wojciechowski, K. W.; Dudek, M. R.; Gatt, R.; Mizzi, L.; Grima, J. N.

    2018-05-01

    The potential of several classes of mechanical metamaterials to induce their own overall rotational motion through the individual rotation of their subunits is examined. Using a theoretical approach, we confirm that for various rotating rigid unit systems, if by design the sum of angular momentum of subunits rotating in different directions is made to be unequal, then the system will experience an overall rotation, the extent of which may be controlled through careful choice of the geometric parameters defining these systems. This phenomenon of self-induced rotation is also confirmed experimentally. Furthermore, we discuss how these systems can be designed in a special way so as to permit extended rotations which allows them to overcome geometric lockage and the relevance of this concept in applications ranging from satellites to spacecraft and telescopes employed in space.

  2. Analytical method for establishing indentation rolling resistance

    NASA Astrophysics Data System (ADS)

    Gładysiewicz, Lech; Konieczna, Martyna

    2018-01-01

    Belt conveyors are highly reliable machines able to work in special operating conditions. Harsh environment, long distance of transporting and great mass of transported martials are cause of high energy usage. That is why research in the field of belt conveyor transportation nowadays focuses on reducing the power consumption without lowering their efficiency. In this paper, previous methods for testing rolling resistance are described, and new method designed by authors was presented. New method of testing rolling resistance is quite simple and inexpensive. Moreover it allows to conduct the experimental tests of the impact of different parameters on the value of indentation rolling resistance such as core design, cover thickness, ambient temperature, idler travel frequency, or load value as well. Finally results of tests of relationship between rolling resistance and idler travel frequency and between rolling resistance and idler travel speed was presented.

  3. Study of blade clearance effects on centrifugal pumps

    NASA Technical Reports Server (NTRS)

    Hoshide, R. K.; Nielson, C. E.

    1972-01-01

    A program of analysis, design, fabrication, and testing has been conducted to develop and experimentally verify analytical models to predict the effects of impeller blade clearance on centrifugal pumps. The effect of tip clearance on pump efficiency, and the relationship between the head coefficient and torque loss with tip clearance was established. Analysis were performed to determine the cost variation in design, manufacture, and test that would occur between unshrouded and shrouded impellers. An impeller, representative of typical rocket engine impellers, was modified by removing its front shroud to permit variation of its blade clearances. It was tested in water with special instrumentation to provide measurements of blade surface pressures during operation. Pump performance data were obtained from tests at various impeller tip clearances. Blade pressure data were obtained at the nominal tip clearance. Comparisons of predicted and measured data are given.

  4. Atomization of coal water mixtures: evaluation of fuel nozzles and a cellulose gum simulant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rosfjord, T.J.

    1985-03-01

    An experimental evaluation of four air-assist fuel nozzles has been conducted to determine atomization levels of coal-water mixture (CWM) fuels at operating conditions simulating a high pressure combustor. Two of the nozzles were commercial units marketed for use in atmospheric burners, while two nozzles were specially designed for CWM operation in a high pressure combustor. Sprays from all four injectors were characterized in tests performed over a range of liquid and air flowrates. Most of the tests were performed using a cellulose-gum water solution prepared to match the viscosity and drip characteristics of an available CWM. Atomization data acquired frommore » a limited test series using the CWM were found to be properly represented by the gum solution data. High levels of atomization (SMD about 10 micron) were achieved by two of the nozzles - one commercial unit and one special unit - at an assist airflow level corresponding to a nozzle air-fuel ratio between 0.6 - 0.8.« less

  5. Lateral specialization in unilateral spatial neglect: a cognitive robotics model.

    PubMed

    Conti, Daniela; Di Nuovo, Santo; Cangelosi, Angelo; Di Nuovo, Alessandro

    2016-08-01

    In this paper, we present the experimental results of an embodied cognitive robotic approach for modelling the human cognitive deficit known as unilateral spatial neglect (USN). To this end, we introduce an artificial neural network architecture designed and trained to control the spatial attentional focus of the iCub robotic platform. Like the human brain, the architecture is divided into two hemispheres and it incorporates bio-inspired plasticity mechanisms, which allow the development of the phenomenon of the specialization of the right hemisphere for spatial attention. In this study, we validate the model by replicating a previous experiment with human patients affected by the USN and numerical results show that the robot mimics the behaviours previously exhibited by humans. We also simulated recovery after the damage to compare the performance of each of the two hemispheres as additional validation of the model. Finally, we highlight some possible advantages of modelling cognitive dysfunctions of the human brain by means of robotic platforms, which can supplement traditional approaches for studying spatial impairments in humans.

  6. Space Software Defined Radio Characterization to Enable Reuse

    NASA Technical Reports Server (NTRS)

    Mortensen, Dale J.; Bishop, Daniel W.; Chelmins, David

    2012-01-01

    NASA's Space Communication and Navigation Testbed is beginning operations on the International Space Station this year. The objective is to promote new software defined radio technologies and associated software application reuse, enabled by this first flight of NASA's Space Telecommunications Radio System architecture standard. The Space Station payload has three software defined radios onboard that allow for a wide variety of communications applications; however, each radio was only launched with one waveform application. By design the testbed allows new waveform applications to be uploaded and tested by experimenters in and outside of NASA. During the system integration phase of the testbed special waveform test modes and stand-alone test waveforms were used to characterize the SDR platforms for the future experiments. Characterization of the Testbed's JPL SDR using test waveforms and specialized ground test modes is discussed in this paper. One of the test waveforms, a record and playback application, can be utilized in a variety of ways, including new satellite on-orbit checkout as well as independent on-board testbed experiments.

  7. Laser Based Color Film Recorder System With GaAs Microlaser

    NASA Astrophysics Data System (ADS)

    Difrancesco, David J.

    1989-07-01

    In 1984 Pixar's research and development group built and applied to the motion-picture arts at Lucasfilm's ILM facility a three color laser based film scanner/recorder system. The digital film printer is capable of reading and writing 35mm film formats on a variety of film stocks. The system has been used in award-winning special-effects work, and has been operated in a normal production environment since that time. The primary objective was to develop a full color high resolution system, free from scan artifacts, enabling traditionally photographed motion-picture film to be inter-cut with digital raster image photography. Its use is applied to the art of blue-screen traveling-matte cinematography for motion pic-ture special effects. The system was designed using the Pixar Image Computer and conventional gas laser technology as the illumination source. This paper will discuss recent experimental work in the application of GaAs microlaser technology to a digital film printing system of the future.

  8. Experimental and numerical investigation of hydro power generator ventilation

    NASA Astrophysics Data System (ADS)

    Jamshidi, H.; Nilsson, H.; Chernoray, V.

    2014-03-01

    Improvements in ventilation and cooling offer means to run hydro power generators at higher power output and at varying operating conditions. The electromagnetic, frictional and windage losses generate heat. The heat is removed by an air flow that is driven by fans and/or the rotor itself. The air flow goes through ventilation channels in the stator, to limit the electrical insulation temperatures. The temperature should be kept limited and uniform in both time and space, avoiding thermal stresses and hot-spots. For that purpose it is important that the flow of cooling air is distributed uniformly, and that flow separation and recirculation are minimized. Improvements of the air flow properties also lead to an improvement of the overall efficiency of the machine. A significant part of the windage losses occurs at the entrance of the stator ventilation channels, where the air flow turns abruptly from tangential to radial. The present work focuses exclusively on the air flow inside a generator model, and in particular on the flow inside the stator channels. The generator model design of the present work is based on a real generator that was previously studied. The model is manufactured taking into consideration the needs of both the experimental and numerical methodologies. Computational Fluid Dynamics (CFD) results have been used in the process of designing the experimental setup. The rotor and stator are manufactured using rapid-prototyping and plexi-glass, yielding a high geometrical accuracy, and optical experimental access. A special inlet section is designed for accurate air flow rate and inlet velocity profile measurements. The experimental measurements include Particle Image Velocimetry (PIV) and total pressure measurements inside the generator. The CFD simulations are performed based on the OpenFOAM CFD toolbox, and the steady-state frozen rotor approach. Specific studies are performed, on the effect of adding "pick-up" to spacers, and the effects of the inlet fan blades on the flow rate through the model. The CFD results capture the experimental flow details to a reasonable level of accuracy.

  9. Hydrogen-enhanced fatigue crack growth in steels and its frequency dependence

    NASA Astrophysics Data System (ADS)

    Matsunaga, Hisao; Takakuwa, Osamu; Yamabe, Junichiro; Matsuoka, Saburo

    2017-06-01

    In the context of the fatigue life design of components, particularly those destined for use in hydrogen refuelling stations and fuel cell vehicles, it is important to understand the hydrogen-induced, fatigue crack growth (FCG) acceleration in steels. As such, the mechanisms for acceleration and its influencing factors are reviewed and discussed in this paper, with a special focus on the peculiar frequency dependence of the hydrogen-induced FCG acceleration. Further, this frequency dependence is debated by introducing some potentially responsible elements, along with new experimental data obtained by the authors. This article is part of the themed issue 'The challenges of hydrogen and metals'.

  10. Multiplexed genome engineering and genotyping methods applications for synthetic biology and metabolic engineering.

    PubMed

    Wang, Harris H; Church, George M

    2011-01-01

    Engineering at the scale of whole genomes requires fundamentally new molecular biology tools. Recent advances in recombineering using synthetic oligonucleotides enable the rapid generation of mutants at high efficiency and specificity and can be implemented at the genome scale. With these techniques, libraries of mutants can be generated, from which individuals with functionally useful phenotypes can be isolated. Furthermore, populations of cells can be evolved in situ by directed evolution using complex pools of oligonucleotides. Here, we discuss ways to utilize these multiplexed genome engineering methods, with special emphasis on experimental design and implementation. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. How honey bees carry pollen

    NASA Astrophysics Data System (ADS)

    Matherne, Marguerite E.; Anyanwu, Gabriel; Leavey, Jennifer K.; Hu, David L.

    2017-11-01

    Honey bees are the tanker of the skies, carrying thirty percent of their weight in pollen per foraging trip using specialized orifices on their body. How do they manage to hang onto those pesky pollen grains? In this experimental study, we investigate the adhesion force of pollen to the honeybee. To affix pollen to themselves, honey bees form a suspension of pollen in nectar, creating a putty-like pollen basket that is skewered by leg hairs. We use tensile tests to show that the viscous force of the pollen basket is more than ten times the honeybee's flight force. This work may provide inspiration for the design of robotic flying pollinators.

  12. Data acquisition and experiment control system of the project Maus (materials science experiments under weightlessness)

    NASA Astrophysics Data System (ADS)

    Lensch, D.

    In the context of Spacelab and Shuttle utilization, it is possible to conduct experiments in 'Small Self Contained Packages' (SSCP). This possibility exists primarily for experiments related to materials research/industrial processing engineering. The program involved is called 'get away special' (GAS). The project Maus was established in West Germany with the aim to participate in the program GAS. The autonomous design of the considered experiments made it necessary to develop an electronic unit for the control and the automatic conduction of the experiment. In addition, the process of the acquisition and the recording of the experimental data is also controlled.

  13. Propellant material compatibility program and results

    NASA Technical Reports Server (NTRS)

    Toth, L. R.; Cannon, W. A.; Coulbert, C. D.; Long, H. R.

    1976-01-01

    The effects of long-term (up to 10 years) contact of inert materials with earth-storable propellants were studied for the purpose of designing chemical propulsion system components that can be used for current as well as future planetary spacecraft. The primary experimental work, and results to date are reported. Investigations include the following propellants: hydrazine, hydrazine-hydrazine nitrate blends, monomethyl-hydrazine, and nitrogen tetroxide. Materials include: aluminum alloys, corrosion-resistant steels, and titanium alloys. More than 700 test specimen capsules were placed in long-term storage testing at 43 C in the special material compatibility facility. Material ratings relative to the 10-year requirement have been assigned.

  14. Investigation of Condensed Media in Weak Fields by the Method of Nuclear Magnetic Resonance

    NASA Astrophysics Data System (ADS)

    Davydov, V. V.; Myazin, N. S.; Dudkin, V. I.; Velichko, E. N.

    2018-05-01

    A compact design of a rapid-response nuclear magnetic spectrometer for investigation of condensed media in weak fields is reported. As a result of investigation of different condensed media, special features of recording a nuclear magnetic resonance (NMR) signal in a weak magnetic field from a small volume of the medium under study are established. For the first time the NMR absorption spectra of condensed media in a weak field are collected. Based on the results of experimental studies, the potential of using a compact NMR-spectrometer for condensed media monitoring in a rapid response mode is determined.

  15. KSC-04pd0497

    NASA Image and Video Library

    2004-03-12

    KENNEDY SPACE CENTER, FLA. - While at the 2004 Florida Regional FIRST competition, held at the University of Central Florida, Center Director Jim Kennedy talks to participants in the FIRST LEGO™ League (FLL). Considered the "little league" of the FIRST (For Inspiration and Recognition of Science and Technology) Robotics Competition, FLL is the result of a partnership between FIRST and the LEGO™ Company. FLL extends the FIRST concept of inspiring and celebrating science and technology to children aged 9 through 14, using real-world context and hands-on experimentation. Young participants can build a robot and compete in a friendly, FIRST-style robotics event specially designed for their age group.

  16. KSC-04pd0498

    NASA Image and Video Library

    2004-03-12

    KENNEDY SPACE CENTER, FLA. - While at the 2004 Florida Regional FIRST competition, held at the University of Central Florida, Center Director Jim Kennedy talks to participants in the FIRST LEGO™ League (FLL). Considered the "little league" of the FIRST (For Inspiration and Recognition of Science and Technology) Robotics Competition, FLL is the result of a partnership between FIRST and the LEGO™ Company. FLL extends the FIRST concept of inspiring and celebrating science and technology to children aged 9 through 14, using real-world context and hands-on experimentation. Young participants can build a robot and compete in a friendly, FIRST-style robotics event specially designed for their age group.

  17. KSC-04pd0505

    NASA Image and Video Library

    2004-03-12

    KENNEDY SPACE CENTER, FLA. - During a break at the 2004 Florida Regional FIRST competition, held at the University of Central Florida, Florida Gov. Jeb Bush joins participants in the FIRST LEGO™ League (FLL). Considered the "little league" of the FIRST (For Inspiration and Recognition of Science and Technology) Robotics Competition, FLL is the result of a partnership between FIRST and the LEGO™ Company. FLL extends the FIRST concept of inspiring and celebrating science and technology to children aged 9 through 14, using real-world context and hands-on experimentation. Young participants can build a robot and compete in a friendly, FIRST-style robotics event specially designed for their age group.

  18. A study of the effects of micro-gravity on seed germination

    NASA Technical Reports Server (NTRS)

    Klein, Lynn Suzanne; Mckibben, Mark; Brain, David A.; Johnson, Theodore C.; Dannenberg, Konrad K.

    1992-01-01

    This study will identify characteristics of seed germination dependent upon gravity. To accomplish this objective, four different seed types will be germinated in space and then be compared to a control group germinated on Earth. Both the experimental and control groups will be analyzed on the cellular level for the size of cells, structural anomalies, and gravitational effects. The experiment will be conducted in a Get Away Special Canister (GAS Can no. 608) owned by the U.S. Space and Rocket Center and designed for students. The GAS Can will remain in the cargo bay of the Space Shuttle with minimal astronaut interaction.

  19. Microwave magnetic field detection based on Cs vapor cell in free space

    NASA Astrophysics Data System (ADS)

    Liu, Xiaochi; Jiang, Zhiyuan; Qu, Jifeng; Hou, Dong; Huang, Xianhe; Sun, Fuyu

    2018-06-01

    In this study, we demonstrate the direct measurement of a microwave (MW) magnetic field through the detection of atomic Rabi resonances with Cs vapor cells in a free-space low-Q cavity. The line shape (amplitude and linewidth) of detected Rabi resonances is investigated versus several experimental parameters such as the laser intensity, cell buffer gas pressure, and cell length. The specially designed low-Q cavity creates a suitable MW environment allowing easy testing of different vapor cells with distinct properties. Obtained results are analyzed to optimize the performances of a MW magnetic field sensor based on the present atom-based detection technique.

  20. KSC-04PD-0497

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. While at the 2004 Florida Regional FIRST competition, held at the University of Central Florida, Center Director Jim Kennedy talks to participants in the FIRST LEGO League (FLL). Considered the 'little league' of the FIRST (For Inspiration and Recognition of Science and Technology) Robotics Competition, FLL is the result of a partnership between FIRST and the LEGO Company. FLL extends the FIRST concept of inspiring and celebrating science and technology to children aged 9 through 14, using real-world context and hands-on experimentation. Young participants can build a robot and compete in a friendly, FIRST-style robotics event specially designed for their age group.

  1. KSC-04PD-0498

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. While at the 2004 Florida Regional FIRST competition, held at the University of Central Florida, Center Director Jim Kennedy talks to participants in the FIRST LEGO League (FLL). Considered the 'little league' of the FIRST (For Inspiration and Recognition of Science and Technology) Robotics Competition, FLL is the result of a partnership between FIRST and the LEGO Company. FLL extends the FIRST concept of inspiring and celebrating science and technology to children aged 9 through 14, using real-world context and hands-on experimentation. Young participants can build a robot and compete in a friendly, FIRST-style robotics event specially designed for their age group.

  2. KSC-04PD-0505

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. During a break at the 2004 Florida Regional FIRST competition, held at the University of Central Florida, Florida Gov. Jeb Bush joins participants in the FIRST LEGO League (FLL). Considered the 'little league' of the FIRST (For Inspiration and Recognition of Science and Technology) Robotics Competition, FLL is the result of a partnership between FIRST and the LEGO Company. FLL extends the FIRST concept of inspiring and celebrating science and technology to children aged 9 through 14, using real-world context and hands-on experimentation. Young participants can build a robot and compete in a friendly, FIRST-style robotics event specially designed for their age group.

  3. On the Physics of Fizziness: How liquid properties control bursting bubble aerosol production?

    NASA Astrophysics Data System (ADS)

    Ghabache, Elisabeth; Antkowiak, Arnaud; Josserand, Christophe; Seon, Thomas

    2014-11-01

    Either in a champagne glass or at the oceanic scales, the tiny capillary bubbles rising at the surface burst in ejecting myriads of droplets. Focusing on the ejected droplets produced by a single bubble, we investigate experimentally how liquid properties and bubble size affect their characteristics: number, ejection velocities, sizes and ejection heights. These results allow us to finely tune the bursting bubble aerosol production. In the context of champagne industry, aerosols play a major role by spreading wine aroma above the glass. We demonstrate that this champagne fizz can be enhanced by selecting the wine viscosity and the bubble size, thanks to specially designed glass.

  4. Performance of a compact, hybrid optical evanescent-wave sensor for chemical and biological applications

    NASA Astrophysics Data System (ADS)

    Helmers, H.; Greco, Pierre; Benech, Pierre; Rustad, Rolf; Kherrat, Rochdi; Bouvier, Gérard

    1996-02-01

    We describe a hybrid evanescent-wave sensor component that we fabricated by using an integrated optical interferometer with a specially adapted photodetector array. The design of the interferometer is based on the use of tapered waveguides to obtain two intersecting collimated beams. Phase shifts can be measured with an angular precision of better than 10-3 rad, which corresponds to a superstrate index change inferior of 10-6 with our structure. The interest in the device as a chemical sensor is experimentally demonstrated. The same optical component could be used in a variety of other sensor applications, e.g., biological and immunological sensors.

  5. Mode-field adapter for tapered-fiber-bundle signal and pump combiners.

    PubMed

    Koška, Pavel; Baravets, Yauhen; Peterka, Pavel; Bohata, Jan; Písařík, Michael

    2015-02-01

    We report on a novel mode-field adapter that is proposed to be incorporated inside tapered fused-fiber-bundle pump and signal combiners for high-power double-clad fiber lasers. Such an adapter allows optimization of signal-mode-field matching on the input and output fibers. Correspondingly, losses of the combiner signal branch are significantly reduced. The mode-field adapter optimization procedure is demonstrated on a combiner based on commercially available fibers. Signal wavelengths of 1.55 and 2 μm are considered. The losses can be further improved by using specially designed intermediate fiber and by dopant diffusion during splicing as confirmed by preliminary experimental results.

  6. 47 CFR 5.64 - Special provisions for satellite systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Section 5.64 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL EXPERIMENTAL RADIO SERVICE... experimental satellite facilities may begin prior to Commission grant of an authorization. Such construction is..., applicants for an experimental authorization involving a satellite system must submit a description of the...

  7. A Reference Method for Measuring Emissions of SVOCs in ...

    EPA Pesticide Factsheets

    Semivolatile organic compounds (SVOCs) are indoor air pollutants that may may have significant adverse effects on human health, and emission of SVOCs from building materials and consumer products is of growing concern. Few chamber studies have been conducted due to the challenges associated with SVOC analysis and the lack of validation procedures. Thus there is an urgent need for a reliable and accurate chamber test method to verify the performance of these measurements. A reference method employing a specially-designed chamber and experimental protocol has been developed and is undergoing extensive evaluation. A pilot interlaboratory study (ILS) has been conducted with five laboratories performing chamber tests under identical conditions. Results showed inter-laboratory variations at 25% for SVOC emission rates, with greater agreement observed between intra-laboratory measurements for most of the participating laboratories. The measured concentration profiles also compared reasonably well to the mechanistic model, demonstrating the feasibility of the proposed reference method to independently assess laboratory performance and validate SVOC emission tests. There is an urgent need for improved understanding of the measurement uncertainties associated with SVOC emissions testing. The creation of specially-designed chambers and well-characterized materials serves as a critical prerequisite for improving the procedure used to measure SVOCs emitted from indoor

  8. DEEP SPACE: High Resolution VR Platform for Multi-user Interactive Narratives

    NASA Astrophysics Data System (ADS)

    Kuka, Daniela; Elias, Oliver; Martins, Ronald; Lindinger, Christopher; Pramböck, Andreas; Jalsovec, Andreas; Maresch, Pascal; Hörtner, Horst; Brandl, Peter

    DEEP SPACE is a large-scale platform for interactive, stereoscopic and high resolution content. The spatial and the system design of DEEP SPACE are facing constraints of CAVETM-like systems in respect to multi-user interactive storytelling. To be used as research platform and as public exhibition space for many people, DEEP SPACE is capable to process interactive, stereoscopic applications on two projection walls with a size of 16 by 9 meters and a resolution of four times 1080p (4K) each. The processed applications are ranging from Virtual Reality (VR)-environments to 3D-movies to computationally intensive 2D-productions. In this paper, we are describing DEEP SPACE as an experimental VR platform for multi-user interactive storytelling. We are focusing on the system design relevant for the platform, including the integration of the Apple iPod Touch technology as VR control, and a special case study that is demonstrating the research efforts in the field of multi-user interactive storytelling. The described case study, entitled "Papyrate's Island", provides a prototypical scenario of how physical drawings may impact on digital narratives. In this special case, DEEP SPACE helps us to explore the hypothesis that drawing, a primordial human creative skill, gives us access to entirely new creative possibilities in the domain of interactive storytelling.

  9. 75 FR 38391 - Special Conditions: Boeing 757-200 With Enhanced Flight Vision System

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    .... SUMMARY: These special conditions are issued for the Boeing Model 757- 200 series airplanes. These... system (EFVS). The EFVS is a novel or unusual design feature which consists of a head-up display (HUD... regulations do not contain adequate or appropriate safety standards for this design feature. These special...

  10. 78 FR 35747 - Special Conditions: Cirrus Design Corporation, Model SF50; Fire Extinguishing for Upper Aft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-14

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 23 [Docket No. CE305; Special Conditions No. 23-245-SC] Special Conditions: Cirrus Design Corporation, Model SF50; Fire... from fires, were not envisioned in the development of the part 23 normal category regulations. The...

  11. 45 CFR 670.25 - Designation of specially protected species of native mammals, birds, and plants.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Designation of specially protected species of native mammals, birds, and plants. 670.25 Section 670.25 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION CONSERVATION OF ANTARCTIC ANIMALS AND PLANTS Specially...

  12. 45 CFR 670.25 - Designation of specially protected species of native mammals, birds, and plants.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Designation of specially protected species of native mammals, birds, and plants. 670.25 Section 670.25 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION CONSERVATION OF ANTARCTIC ANIMALS AND PLANTS Specially...

  13. 45 CFR 670.25 - Designation of specially protected species of native mammals, birds, and plants.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 3 2012-10-01 2012-10-01 false Designation of specially protected species of native mammals, birds, and plants. 670.25 Section 670.25 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION CONSERVATION OF ANTARCTIC ANIMALS AND PLANTS Specially...

  14. 7 CFR 868.264 - Special grade designation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... FOR CERTAIN AGRICULTURAL COMMODITIES United States Standards for Brown Rice for Processing Special.... The grade designation for parboiled, smutty, glutinous, or aromatic brown rice for processing shall...

  15. 7 CFR 868.264 - Special grade designation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... FOR CERTAIN AGRICULTURAL COMMODITIES United States Standards for Brown Rice for Processing Special.... The grade designation for parboiled, smutty, glutinous, or aromatic brown rice for processing shall...

  16. New Reactor Physics Benchmark Data in the March 2012 Edition of the IRPhEP Handbook

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    John D. Bess; J. Blair Briggs; Jim Gulliford

    2012-11-01

    The International Reactor Physics Experiment Evaluation Project (IRPhEP) was established to preserve integral reactor physics experimental data, including separate or special effects data for nuclear energy and technology applications. Numerous experiments that have been performed worldwide, represent a large investment of infrastructure, expertise, and cost, and are valuable resources of data for present and future research. These valuable assets provide the basis for recording, development, and validation of methods. If the experimental data are lost, the high cost to repeat many of these measurements may be prohibitive. The purpose of the IRPhEP is to provide an extensively peer-reviewed set ofmore » reactor physics-related integral data that can be used by reactor designers and safety analysts to validate the analytical tools used to design next-generation reactors and establish the safety basis for operation of these reactors. Contributors from around the world collaborate in the evaluation and review of selected benchmark experiments for inclusion in the International Handbook of Evaluated Reactor Physics Benchmark Experiments (IRPhEP Handbook) [1]. Several new evaluations have been prepared for inclusion in the March 2012 edition of the IRPhEP Handbook.« less

  17. Software for Acoustic Rendering

    NASA Technical Reports Server (NTRS)

    Miller, Joel D.

    2003-01-01

    SLAB is a software system that can be run on a personal computer to simulate an acoustic environment in real time. SLAB was developed to enable computational experimentation in which one can exert low-level control over a variety of signal-processing parameters, related to spatialization, for conducting psychoacoustic studies. Among the parameters that can be manipulated are the number and position of reflections, the fidelity (that is, the number of taps in finite-impulse-response filters), the system latency, and the update rate of the filters. Another goal in the development of SLAB was to provide an inexpensive means of dynamic synthesis of virtual audio over headphones, without need for special-purpose signal-processing hardware. SLAB has a modular, object-oriented design that affords the flexibility and extensibility needed to accommodate a variety of computational experiments and signal-flow structures. SLAB s spatial renderer has a fixed signal-flow architecture corresponding to a set of parallel signal paths from each source to a listener. This fixed architecture can be regarded as a compromise that optimizes efficiency at the expense of complete flexibility. Such a compromise is necessary, given the design goal of enabling computational psychoacoustic experimentation on inexpensive personal computers.

  18. On the suitability of different representations of solid catalysts for combinatorial library design by genetic algorithms.

    PubMed

    Gobin, Oliver C; Schüth, Ferdi

    2008-01-01

    Genetic algorithms are widely used to solve and optimize combinatorial problems and are more often applied for library design in combinatorial chemistry. Because of their flexibility, however, their implementation can be challenging. In this study, the influence of the representation of solid catalysts on the performance of genetic algorithms was systematically investigated on the basis of a new, constrained, multiobjective, combinatorial test problem with properties common to problems in combinatorial materials science. Constraints were satisfied by penalty functions, repair algorithms, or special representations. The tests were performed using three state-of-the-art evolutionary multiobjective algorithms by performing 100 optimization runs for each algorithm and test case. Experimental data obtained during the optimization of a noble metal-free solid catalyst system active in the selective catalytic reduction of nitric oxide with propene was used to build up a predictive model to validate the results of the theoretical test problem. A significant influence of the representation on the optimization performance was observed. Binary encodings were found to be the preferred encoding in most of the cases, and depending on the experimental test unit, repair algorithms or penalty functions performed best.

  19. Gradual training of alpacas to the confinement of metabolism pens reduces stress when normal excretion behavior is accommodated.

    PubMed

    Lund, Kirrin E; Maloney, Shane K; Milton, John T B; Blache, Dominique

    2012-01-01

    Confinement in metabolism pens may provoke a stress response in alpacas that will reduce the welfare of the animal and jeopardize the validity of scientific results obtained in such pens. In this study, we tested a protocol designed to successfully train alpacas to be held in a specially designed metabolism pen so that the animals' confinement would not jeopardize their welfare. We hypothesized that the alpacas would show fewer behaviors associated with a response to stress as training gradually progressed, and that they would adapt to being in the confinement of the metabolism pen. The training protocol was successful at introducing alpacas to the metabolism pens, and it did reduce the incidence of behavioral responses to stress as the training progressed. The success of the training protocol may be attributed to the progressive nature of the training, the tailoring of the protocol to suit alpacas, and the use of positive reinforcement. This study demonstrated that both animal welfare and the validity of the scientific outcomes could be maximized by the gradual training of experimental animals, thereby minimizing the stress imposed on the animals during experimental procedures.

  20. Permutation inference for the general linear model

    PubMed Central

    Winkler, Anderson M.; Ridgway, Gerard R.; Webster, Matthew A.; Smith, Stephen M.; Nichols, Thomas E.

    2014-01-01

    Permutation methods can provide exact control of false positives and allow the use of non-standard statistics, making only weak assumptions about the data. With the availability of fast and inexpensive computing, their main limitation would be some lack of flexibility to work with arbitrary experimental designs. In this paper we report on results on approximate permutation methods that are more flexible with respect to the experimental design and nuisance variables, and conduct detailed simulations to identify the best method for settings that are typical for imaging research scenarios. We present a generic framework for permutation inference for complex general linear models (glms) when the errors are exchangeable and/or have a symmetric distribution, and show that, even in the presence of nuisance effects, these permutation inferences are powerful while providing excellent control of false positives in a wide range of common and relevant imaging research scenarios. We also demonstrate how the inference on glm parameters, originally intended for independent data, can be used in certain special but useful cases in which independence is violated. Detailed examples of common neuroimaging applications are provided, as well as a complete algorithm – the “randomise” algorithm – for permutation inference with the glm. PMID:24530839

  1. Experimental evaluation of job provenance in ATLAS environment

    NASA Astrophysics Data System (ADS)

    Křenek, A.; Sitera, J.; Chudoba, J.; Dvořák, F.; Filipovič, J.; Kmuníček, J.; Matyska, L.; Mulaš, M.; Ruda, M.; Šustr, Z.; Campana, S.; Molinari, E.; Rebatto, D.

    2008-07-01

    Grid middleware stacks, including gLite, matured into the state of being able to process up to millions of jobs per day. Logging and Bookkeeping, the gLite job-tracking service, keeps pace with this rate; however, it is not designed to provide a long-term archive of information on executed jobs. ATLAS — representative of a large user community — addresses this issue with its own job catalogue (ProdDB). Development of such a customized service, not easily reusable, took considerable effort which is not affordable by smaller communities. On the contrary, Job Provenance (JP), a generic gLite service designed for long-term archiving of information on executed jobs focusing on scalability, extensibility, uniform data view, and configurability, allows more specialized catalogues to be easily built. We present the first results of an experimental JP deployment for the ATLAS production infrastructure where a JP installation was fed with a part of ATLAS jobs, and also stress tested with real production data. The main outcome of this work is a demonstration that JP can complement large-scale application-specific job catalogue services, while serving a similar purpose where there are none available.

  2. Design, Fabrication and Characterization of a Low-Impedance 3D Electrode Array System for Neuro-Electrophysiology

    PubMed Central

    Kusko, Mihaela; Craciunoiu, Florea; Amuzescu, Bogdan; Halitzchi, Ferdinand; Selescu, Tudor; Radoi, Antonio; Popescu, Marian; Simion, Monica; Bragaru, Adina; Ignat, Teodora

    2012-01-01

    Recent progress in patterned microelectrode manufacturing technology and microfluidics has opened the way to a large variety of cellular and molecular biosensor-based applications. In this extremely diverse and rapidly expanding landscape, silicon-based technologies occupy a special position, given their statute of mature, consolidated, and highly accessible areas of development. Within the present work we report microfabrication procedures and workflows for 3D patterned gold-plated microelectrode arrays (MEA) of different shapes (pyramidal, conical and high aspect ratio), and we provide a detailed characterization of their physical features during all the fabrication steps to have in the end a reliable technology. Moreover, the electrical performances of MEA silicon chips mounted on standardized connector boards via ultrasound wire-bonding have been tested using non-destructive electrochemical methods: linear sweep and cyclic voltammetry, impedance spectroscopy. Further, an experimental recording chamber package suitable for in vitro electrophysiology experiments has been realized using custom-design electronics for electrical stimulus delivery and local field potential recording, included in a complete electrophysiology setup, and the experimental structures have been tested on newborn rat hippocampal slices, yielding similar performance compared to commercially available MEA equipments. PMID:23208555

  3. Wind turbine blade fatigue tests: lessons learned and application to SHM system development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Taylor, Stuart G.; Farinholt, Kevin M.; Jeong, Hyomi

    2012-06-28

    This paper presents experimental results of several structural health monitoring (SHM) methods applied to a 9-meter CX-100 wind turbine blade that underwent fatigue loading. The blade was instrumented with piezoelectric transducers, accelerometers, acoustic emission sensors, and foil strain gauges. It underwent harmonic excitation at its first natural frequency using a hydraulically actuated resonant excitation system. The blade was initially excited at 25% of its design load, and then with steadily increasing loads until it failed. Various data were collected between and during fatigue loading sessions. The data were measured over multiple frequency ranges using a variety of acquisition equipment, includingmore » off-the-shelf systems and specially designed hardware developed by the authors. Modal response, diffuse wave-field transfer functions, and ultrasonic guided wave methods were applied to assess the condition of the wind turbine blade. The piezoelectric sensors themselves were also monitored using a sensor diagnostics procedure. This paper summarizes experimental procedures and results, focusing particularly on fatigue crack detection, and concludes with considerations for implementing such damage identification systems, which will be used as a guideline for future SHM system development for operating wind turbine blades.« less

  4. Optical Interface States Protected by Synthetic Weyl Points

    NASA Astrophysics Data System (ADS)

    Wang, Qiang; Xiao, Meng; Liu, Hui; Zhu, Shining; Chan, C. T.

    2017-07-01

    Weyl fermions have not been found in nature as elementary particles, but they emerge as nodal points in the band structure of electronic and classical wave crystals. Novel phenomena such as Fermi arcs and chiral anomaly have fueled the interest in these topological points which are frequently perceived as monopoles in momentum space. Here, we report the experimental observation of generalized optical Weyl points inside the parameter space of a photonic crystal with a specially designed four-layer unit cell. The reflection at the surface of a truncated photonic crystal exhibits phase vortexes due to the synthetic Weyl points, which in turn guarantees the existence of interface states between photonic crystals and any reflecting substrates. The reflection phase vortexes have been confirmed for the first time in our experiments, which serve as an experimental signature of the generalized Weyl points. The existence of these interface states is protected by the topological properties of the Weyl points, and the trajectories of these states in the parameter space resembles those of Weyl semimetal "Fermi arc surface states" in momentum space. Tracing the origin of interface states to the topological character of the parameter space paves the way for a rational design of strongly localized states with enhanced local field.

  5. An experimental study of resistant properties of the small intestine for an active capsule endoscope.

    PubMed

    Wang, X; Meng, M Q-H

    2010-01-01

    Use of the capsule endoscope (CE) in clinical examinations is limited by its passive movement resulting from the natural peristalsis of the gastrointestinal (GI) tract. Therefore, a locomotion mechanism is desirable for the next generation of capsule endoscope. Understanding the resistant properties of the small intestine is essential for designing a wireless magnetic actuation mechanism. In this paper, in vitro experiments were carried out to investigate the resistant force of the small intestine using 15 specially designed capsule prototypes and analysed the effect of the capsule dimension and moving speed. Segments of porcine small intestine were employed as a conservative model for the human intestine. When the capsules under experiment were moving at a speed of 0.5 mm/s, a resistant force of 20 to 100 mN were measured for the capsule diameter in the range of 8 to 13 mm. The force increased with moving speed. The intrinsic cause of the resistant force of the small intestine is discussed based on an analysis of the experimental data. It is believed that the viscoelastic properties of the tissue play an important role in the resistant characteristics of the small intestine.

  6. Design of an experimental apparatus for measurement of the surface tension of metastable fluids

    NASA Astrophysics Data System (ADS)

    Vinš, V.; Hrubý, J.; Hykl, J.; Blaha, J.; Šmíd, B.

    2013-04-01

    A unique experimental apparatus for measurement of the surface tension of aqueous mixtures has been designed, manufactured, and tested in our laboratory. The novelty of the setup is that it allows measurement of surface tension by two different methods: a modified capillary elevation method in a long vertical capillary tube and a method inspired by the approach of Hacker (National Advisory Committee for Aeronautics, Technical Note 2510, 1-20, 1951), i.e. in a short horizontal capillary tube. Functionality of all main components of the apparatus, e.g., glass chamber with the capillary tube, temperature control unit consisting of two thermostatic baths with special valves for rapid temperature jumps, helium distribution setup allowing pressure variation above the liquid meniscus inside the capillary tube, has been successfully tested. Preliminary results for the surface tension of the stable and metastable supercooled water measured by the capillary elevation method at atmospheric pressure are provided. The surface tension of water measured at temperatures between +26 °C and -11 °C is in good agreement with the extrapolated IAPWS correlation (IAPWS Release on Surface Tension of Ordinary Water Substance, September 1994); however it disagrees with data by Hacker.

  7. Research on stability of nozzle-floating plate institution

    NASA Astrophysics Data System (ADS)

    Huang, Bin; Tao, Jiayue; Yi, Jiajing; Chen, Shijing

    2016-01-01

    In this paper, air hammer instability of nozzle-floating plate institution in gas lubricated force sensor were studied. Through establishment of the theoretical model for the analysis of the nozzle-floating plate institution stability, combined with air hammer stability judgment theorems, we had some simulation research on the radius of the nozzle, the radius of the pressure chamber, pressure chamber depth, orifice radius and the relationship between air supply pressure and bearing capacity, in order to explore the instability mechanism of nozzle-floating plate institution. For conducting experimental observations for the stability of two groups nozzle-floating plate institution, which have typical structural parameters conducted experimental observations. We set up a special experimental device, verify the correctness of the theoretical study and simulation results. This paper shows that in the nozzle-floating plate institution, increasing the nozzle diameter, reduced pressure chamber radius, reducing the depth of the pressure chamber and increase the supply orifice radius, and other measures is conducive to system stability. Results of this study have important implications for research and design of gas lubricated force sensor.

  8. The IXV experience, from the mission conception to the flight results

    NASA Astrophysics Data System (ADS)

    Tumino, G.; Mancuso, S.; Gallego, J.-M.; Dussy, S.; Preaud, J.-P.; Di Vita, G.; Brunner, P.

    2016-07-01

    The atmospheric re-entry domain is a cornerstone of a wide range of space applications, ranging from reusable launcher stages developments, robotic planetary exploration, human space flight, to innovative applications such as reusable research platforms for in orbit validation of multiple space applications technologies. The Intermediate experimental Vehicle (IXV) is an advanced demonstrator which has performed in-flight experimentation of atmospheric re-entry enabling systems and technologies aspects, with significant advancements on Europe's previous flight experiences, consolidating Europe's autonomous position in the strategic field of atmospheric re-entry. The IXV mission objectives were the design, development, manufacturing, assembling and on-ground to in-flight verification of an autonomous European lifting and aerodynamically controlled reentry system, integrating critical re-entry technologies at system level. Among such critical technologies of interest, special attention was paid to aerodynamic and aerothermodynamics experimentation, including advanced instrumentation for aerothermodynamics phenomena investigations, thermal protections and hot-structures, guidance, navigation and flight control through combined jets and aerodynamic surfaces (i.e. flaps), in particular focusing on the technologies integration at system level for flight, successfully performed on February 11th, 2015.

  9. Research Designs and Special Education Research: Different Designs Address Different Questions

    ERIC Educational Resources Information Center

    Cook, Bryan G.; Cook, Lysandra

    2016-01-01

    The aim of this article is to provide practitioners and other nonresearchers a basic understanding of research designs to aid in appropriately interpreting and applying research findings in special education. Research design provides the blueprint for conducting a research study and shapes what kind of knowledge is generated by the study. We…

  10. X-33 Attitude Control Using the XRS-2200 Linear Aerospike Engine

    NASA Technical Reports Server (NTRS)

    Hall, Charles E.; Panossian, Hagop V.

    1999-01-01

    The Vehicle Control Systems Team at Marshall Space Flight Center, Structures and Dynamics Laboratory, Guidance and Control Systems Division is designing, under a cooperative agreement with Lockheed Martin Skunkworks, the Ascent, Transition, and Entry flight attitude control systems for the X-33 experimental vehicle. Test flights, while suborbital, will achieve sufficient altitudes and Mach numbers to test Single Stage To Orbit, Reusable Launch Vehicle technologies. Ascent flight control phase, the focus of this paper, begins at liftoff and ends at linear aerospike main engine cutoff (MECO). The X-33 attitude control system design is confronted by a myriad of design challenges: a short design cycle, the X-33 incremental test philosophy, the concurrent design philosophy chosen for the X-33 program, and the fact that the attitude control system design is, as usual, closely linked to many other subsystems and must deal with constraints and requirements from these subsystems. Additionally, however, and of special interest, the use of the linear aerospike engine is a departure from the gimbaled engines traditionally used for thrust vector control (TVC) in launch vehicles and poses certain design challenges. This paper discusses the unique problem of designing the X-33 attitude control system with the linear aerospike engine, requirements development, modeling and analyses that verify the design.

  11. A New Type of Motor: Pneumatic Step Motor

    PubMed Central

    Stoianovici, Dan; Patriciu, Alexandru; Petrisor, Doru; Mazilu, Dumitru; Kavoussi, Louis

    2011-01-01

    This paper presents a new type of pneumatic motor, a pneumatic step motor (PneuStep). Directional rotary motion of discrete displacement is achieved by sequentially pressurizing the three ports of the motor. Pulsed pressure waves are generated by a remote pneumatic distributor. The motor assembly includes a motor, gearhead, and incremental position encoder in a compact, central bore construction. A special electronic driver is used to control the new motor with electric stepper indexers and standard motion control cards. The motor accepts open-loop step operation as well as closed-loop control with position feedback from the enclosed sensor. A special control feature is implemented to adapt classic control algorithms to the new motor, and is experimentally validated. The speed performance of the motor degrades with the length of the pneumatic hoses between the distributor and motor. Experimental results are presented to reveal this behavior and set the expectation level. Nevertheless, the stepper achieves easily controllable precise motion unlike other pneumatic motors. The motor was designed to be compatible with magnetic resonance medical imaging equipment, for actuating an image-guided intervention robot, for medical applications. For this reason, the motors were entirely made of nonmagnetic and dielectric materials such as plastics, ceramics, and rubbers. Encoding was performed with fiber optics, so that the motors are electricity free, exclusively using pressure and light. PneuStep is readily applicable to other pneumatic or hydraulic precision-motion applications. PMID:21528106

  12. Process analytical technology (PAT) approach to the formulation of thermosensitive protein-loaded pellets: Multi-point monitoring of temperature in a high-shear pelletization.

    PubMed

    Kristó, Katalin; Kovács, Orsolya; Kelemen, András; Lajkó, Ferenc; Klivényi, Gábor; Jancsik, Béla; Pintye-Hódi, Klára; Regdon, Géza

    2016-12-01

    In the literature there are some publications about the effect of impeller and chopper speeds on product parameters. However, there is no information about the effect of temperature. Therefore our main aim was the investigation of elevated temperature and temperature distribution during pelletization in a high shear granulator according to process analytical technology. During our experimental work, pellets containing pepsin were formulated with a high-shear granulator. A specially designed chamber (Opulus Ltd.) was used for pelletization. This chamber contained four PyroButton-TH® sensors built in the wall and three PyroDiff® sensors 1, 2 and 3cm from the wall. The sensors were located in three different heights. The impeller and chopper speeds were set on the basis of 3 2 factorial design. The temperature was measured continuously in 7 different points during pelletization and the results were compared with the temperature values measured by the thermal sensor of the high-shear granulator. The optimization parameters were enzyme activity, average size, breaking hardness, surface free energy and aspect ratio. One of the novelties was the application of the specially designed chamber (Opulus Ltd.) for monitoring the temperature continuously in 7 different points during high-shear granulation. The other novelty of this study was the evaluation of the effect of temperature on the properties of pellets containing protein during high-shear pelletization. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. A special purpose silicon compiler for designing supercomputing VLSI systems

    NASA Technical Reports Server (NTRS)

    Venkateswaran, N.; Murugavel, P.; Kamakoti, V.; Shankarraman, M. J.; Rangarajan, S.; Mallikarjun, M.; Karthikeyan, B.; Prabhakar, T. S.; Satish, V.; Venkatasubramaniam, P. R.

    1991-01-01

    Design of general/special purpose supercomputing VLSI systems for numeric algorithm execution involves tackling two important aspects, namely their computational and communication complexities. Development of software tools for designing such systems itself becomes complex. Hence a novel design methodology has to be developed. For designing such complex systems a special purpose silicon compiler is needed in which: the computational and communicational structures of different numeric algorithms should be taken into account to simplify the silicon compiler design, the approach is macrocell based, and the software tools at different levels (algorithm down to the VLSI circuit layout) should get integrated. In this paper a special purpose silicon (SPS) compiler based on PACUBE macrocell VLSI arrays for designing supercomputing VLSI systems is presented. It is shown that turn-around time and silicon real estate get reduced over the silicon compilers based on PLA's, SLA's, and gate arrays. The first two silicon compiler characteristics mentioned above enable the SPS compiler to perform systolic mapping (at the macrocell level) of algorithms whose computational structures are of GIPOP (generalized inner product outer product) form. Direct systolic mapping on PLA's, SLA's, and gate arrays is very difficult as they are micro-cell based. A novel GIPOP processor is under development using this special purpose silicon compiler.

  14. Experimenting with Support of Mobile Touch Devices for Pupils with Special Educational Needs

    ERIC Educational Resources Information Center

    Gybas, Vojtech; Kostolányová, Katerina; Klubal, Libor

    2017-01-01

    The aim of this paper is to describe one of the learning option for pupils with special educational needs with the support of ICT in the educational area Man and Nature, "a basic knowledge of chemistry." Form of experimental teaching is not commonly used in elementary school special education. With the support of ICT, specifically the…

  15. Comparative Outcomes of Two Instructional Models for Students with Learning Disabilities: Inclusion with Co-Teaching and Solo-Taught Special Education

    ERIC Educational Resources Information Center

    Tremblay, Philippe

    2013-01-01

    We compared two instructional models (co-teaching inclusion and solo-taught special education) for students with learning disabilities (LD) with regard to their effect on academic achievement and class attendance. Twelve inclusive classes (experimental group) and 13 special education classes (control group) participated in the study. In grade 1,…

  16. Preface of the special issue quantum foundations: information approach

    PubMed Central

    2016-01-01

    This special issue is based on the contributions of a group of top experts in quantum foundations and quantum information and probability. It enlightens a number of interpretational, mathematical and experimental problems of quantum theory. PMID:27091161

  17. Aeroelasticity matters: Some reflections on two decades of testing in the NASA Langley transonic dynamics tunnel

    NASA Technical Reports Server (NTRS)

    Reed, W. H., III

    1981-01-01

    Testing of wind-tunnel aeroelastic models is a well established, widely used means of studying flutter trends, validating theory and investigating flutter margins of safety of new vehicle designs. The Langley Transonic Dynamics Tunnel was designed specifically for work on dynamics and aeroelastic problems of aircraft and space vehicles. A cross section of aeroelastic research and testing in the facility since it became operational more than two decades ago is presented. Examples selected from a large store of experience illustrate the nature and purpose of some major areas of work performed in the tunnel. These areas include: specialized experimental techniques; development testing of new aircraft and launch vehicle designs; evaluation of proposed "fixes" to solve aeroelastic problems uncovered during development testing; study of unexpected aeroelastic phenomena (i.e., "surprises"); control of aeroelastic effects by active and passive means; and, finally, fundamental research involving measurement of unsteady pressures on oscillating wings and control surface.

  18. XAPiir: A recursive digital filtering package

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harris, D.

    1990-09-21

    XAPiir is a basic recursive digital filtering package, containing both design and implementation subroutines. XAPiir was developed for the experimental array processor (XAP) software package, and is written in FORTRAN. However, it is intended to be incorporated into any general- or special-purpose signal analysis program. It replaces the older package RECFIL, offering several enhancements. RECFIL is used in several large analysis programs developed at LLNL, including the seismic analysis package SAC, several expert systems (NORSEA and NETSEA), and two general purpose signal analysis packages (SIG and VIEW). This report is divided into two sections: the first describes the use ofmore » the subroutine package, and the second, its internal organization. In the first section, the filter design problem is briefly reviewed, along with the definitions of the filter design parameters and their relationship to the subroutine input parameters. In the second section, the internal organization is documented to simplify maintenance and extensions to the package. 5 refs., 9 figs.« less

  19. Considerations on Experimental Design and Data Analysis of Chromatin Immunoprecipitation Experiments.

    PubMed

    Jordán-Pla, Antonio; Visa, Neus

    2018-01-01

    Arguably one of the most valuable techniques to study chromatin organization, ChIP is the method of choice to map the contacts established between proteins and genomic DNA. Ever since its inception, more than 30 years ago, ChIP has been constantly evolving, improving, and expanding its capabilities and reach. Despite its widespread use by many laboratories across a wide variety of disciplines, ChIP assays can be sometimes challenging to design, and are often sensitive to variations in practical implementation.In this chapter, we provide a general overview of the ChIP method and its most common variations, with a special focus on ChIP-seq. We try to address some of the most important aspects that need to be taken into account in order to design and perform experiments that generate the most reproducible, high-quality data. Some of the main topics covered include the use of properly characterized antibodies, alternatives to chromatin preparation, the need for proper controls, and some recommendations about ChIP-seq data analysis.

  20. Optimization of soy isoflavone extraction with different solvents using the simplex-centroid mixture design.

    PubMed

    Yoshiara, Luciane Yuri; Madeira, Tiago Bervelieri; Delaroza, Fernanda; da Silva, Josemeyre Bonifácio; Ida, Elza Iouko

    2012-12-01

    The objective of this study was to optimize the extraction of different isoflavone forms (glycosidic, malonyl-glycosidic, aglycone and total) from defatted cotyledon soy flour using the simplex-centroid experimental design with four solvents of varying polarity (water, acetone, ethanol and acetonitrile). The obtained extracts were then analysed by high-performance liquid chromatography. The profile of the different soy isoflavones forms varied with different extractions solvents. Varying the solvent or mixture used, the extraction of different isoflavones was optimized using the centroid-simplex mixture design. The special cubic model best fitted to the four solvents and its combination for soy isoflavones extraction. For glycosidic isoflavones extraction, the polar ternary mixture (water, acetone and acetonitrile) achieved the best extraction; malonyl-glycosidic forms were better extracted with mixtures of water, acetone and ethanol. Aglycone isoflavones, water and acetone mixture were best extracted and total isoflavones, the best solvents were ternary mixture of water, acetone and ethanol.

  1. Design, analysis, fabrication and test of the Space Shuttle solid rocket booster motor case

    NASA Technical Reports Server (NTRS)

    Kapp, J. R.

    1978-01-01

    The motor case used in the solid propellant booster for the Space Shuttle is unique in many respects, most of which are indigenous to size and special design requirements. The evolution of the case design from initial requirements to finished product is discussed, with increased emphasis of reuse capability, special design features, fracture mechanics and corrosion control. Case fabrication history and the resulting procedure are briefly reviewed with respect to material development, processing techniques and special problem areas. Case assembly, behavior and performance during the DM-1 static firing are reviewed, with appropriate comments and conclusions.

  2. Inclusive Design: Building Educator Evaluation Systems That Support Students with Disabilities. Special Issues Brief. Revised Edition

    ERIC Educational Resources Information Center

    Holdheide, Lynn

    2013-01-01

    This Special Issues Brief from the Center on Great Teachers and Leaders (GTL Center) offers recommendations for the design and implementation of educator evaluation systems that support the academic and social growth of students with disabilities. Teachers of students with disabilities work closely with specialized instructional support personnel…

  3. 78 FR 64415 - Special Conditions: Airbus, Model A350-900 Series Airplane; Ground Pivoting Loads

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-29

    ... series because of a novel or unusual design feature, special conditions are prescribed under Sec. 21.16... A350-900 series airplane will incorporate the following novel or unusual design features: a braking...-0890; Notice No. 25-13-10-SC] Special Conditions: Airbus, Model A350-900 Series Airplane; Ground...

  4. 32 CFR Appendix B to Part 80 - Procedures for Special Educational Programs (Including Related Services) for Preschool Children...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the regular physical education program available to students without disabilities unless: a. The... child or child with a disability needs specially designed physical education, as prescribed in his or her IEP. 4. If specially designed physical education services are prescribed in the IEP of a preschool...

  5. 31 CFR Appendix A to Chapter V - Information Pertaining to the Specially Designated Nationals and Blocked Persons List

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Specially Designated Nationals and Blocked Persons List A Appendix A to Chapter V Money and Finance... OF THE TREASURY Ch. V, App. A Appendix A to Chapter V—Information Pertaining to the Specially... the economic sanctions programs in chapter V. 6. Specific licenses previously issued by OFAC may...

  6. 75 FR 20516 - Special Conditions: Cirrus Design Corporation, Model SF50; Fire Extinguishing for Upper Aft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-20

    ...; Special Conditions No. 23-245-SC] Special Conditions: Cirrus Design Corporation, Model SF50; Fire... protect such installed engines from fires, were not envisioned in the development of the part 23 normal... condition for the fire extinguishing system for the engine on the model SF50 is required. Regulations...

  7. Investigating Experimental Effects within the Framework of Structural Equation Modeling: An Example with Effects on Both Error Scores and Reaction Times

    ERIC Educational Resources Information Center

    Schweizer, Karl

    2008-01-01

    Structural equation modeling provides the framework for investigating experimental effects on the basis of variances and covariances in repeated measurements. A special type of confirmatory factor analysis as part of this framework enables the appropriate representation of the experimental effect and the separation of experimental and…

  8. 78 FR 45011 - Designation of Bulut Yayla, AKA: Samet Ince as a Specially Designated Global Terrorist Pursuant...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ... DEPARTMENT OF STATE [Public Notice 8390] Designation of Bulut Yayla, AKA: Samet Ince as a Specially Designated Global Terrorist Pursuant to Section 1(b) of Executive Order 13224, as Amended Acting under the authority of and in accordance with section 1(b) of Executive Order 13224 of September 23...

  9. Recent Innovations in the Changing Criterion Design: Implications for Research and Practice in Special Education

    ERIC Educational Resources Information Center

    McDougall, Dennis; Hawkins, Jacqueline; Brady, Michael; Jenkins, Amelia

    2006-01-01

    This article illustrates (a) 2 recent innovations in the changing criterion research design, (b) how these innovations apply to research and practice in special education, and (c) how clinical needs influence design features of the changing criterion design. The first innovation, the range-bound changing criterion, is a very simple variation of…

  10. FR4-based electromagnetic energy harvester for wireless sensor nodes

    NASA Astrophysics Data System (ADS)

    Hatipoglu, G.; Ürey, H.

    2010-01-01

    Electromagnetic (EM) energy harvesting seems to be one of the most promising ways to power wireless sensors in a wireless sensor network. In this paper, FR4, the most commonly used PCB material, is utilized as a mechanical vibrating structure for EM energy harvesting for body-worn sensors and intelligent tire sensors, which involve impact loadings. FR4 can be a better material for such applications compared to silicon MEMS devices due to lower stiffness and broadband response. In order to demonstrate FR4 performance and broadband response, three moving magnet type EM generator designs are developed and investigated throughout the paper. A velocity-damped harvester simulation model is first developed, including a detailed magnetic model and the magnetic damping effects. The numerical results agree well with the experimental results. Human running acceleration at the hip area that is obtained experimentally is simulated in order to demonstrate system performance, which results in a scavenged power of about 40 µW with 15 m s-2 acceleration input. The designed FR4 energy scavengers with mechanical stoppers implemented are particularly well suited for nearly periodic and non-sinusoidal high- g excitations with rich harmonic content. For the intelligent tire applications, a special compact FR4 scavenger is designed that is able to withstand large shocks and vibrations due to mechanical shock stoppers built into the structure. Using our design, 0.4 mW power across a load resistance at off-resonance operation is obtained in shaker experiments. In the actual operation, the tangential accelerations as a result of the tire-road contact are estimated to supply power around 1 mW with our design, which is sufficient for powering wireless tire sensors. The normalized power density (NPD) of the designed actuators compares favorably with most actuators reported in the literature.

  11. Design complexity in termite-fishing tools of chimpanzees (Pan troglodytes)

    PubMed Central

    Sanz, Crickette; Call, Josep; Morgan, David

    2009-01-01

    Adopting the approach taken with New Caledonian crows (Corvus moneduloides), we present evidence of design complexity in one of the termite-fishing tools of chimpanzees (Pan troglodytes) in the Goualougo Triangle, Republic of Congo. Prior to termite fishing, chimpanzees applied a set of deliberate, distinguishable actions to modify herb stems to fashion a brush-tipped probe, which is different from the form of fishing tools used by chimpanzees in East and West Africa. This means that ‘brush-tipped fishing probes’, unlike ‘brush sticks’, are not a by-product of use but a deliberate design feature absent in other chimpanzee populations. The specialized modifications to prepare the tool for termite fishing, measures taken to repair non-functional brushes and appropriate orientation of the modified end suggest that these wild chimpanzees are attentive to tool modifications. We also conducted experimental trials that showed that a brush-tipped probe is more effective in gathering insects than an unmodified fishing probe. Based on these findings, we suggest that chimpanzees in the Congo Basin have developed an improved fishing probe design. PMID:19324641

  12. Concept and design of charged particle optics using energy Fourier plane collimation

    NASA Astrophysics Data System (ADS)

    Yang, Guojun; Wei, Tao; Zhang, Zhuo; He, Xiaozhong; Zhang, Xiaoding; Li, Yiding; Shi, Jinshui

    2014-09-01

    Charged particle radiography has become a promising new approach in the field of transmission radiography because of the invention of the magnetic imaging lens. The using of the imaging lens makes it possible for thick objects to get significantly improved transmission radiography. Currently, the conventional charged particle radiography only uses the information of the flux attenuation and the angular scattering of the transmitted particles to determine the properties of the sample. However, the energy loss of the incident particles introduced by ionizations throughout the object limits the spatial resolution of the image because of the chromatic blur. In this paper a new concept of imaging lens that uses the information of the energy loss is proposed. With a specially designed imaging lens, the information of the energy loss could result in apparent contrast in the final image. This design procedure of the energy loss imaging lens is presented, and a preliminary design is verified by numerical simulations. Experimental demonstration is also expected on a cyclotron at the Institute of Fluid Physics, CAEP.

  13. [System design of small intellectualized ultrasound hyperthermia instrument in the LabVIEW environment].

    PubMed

    Jiang, Feng; Bai, Jingfeng; Chen, Yazhu

    2005-08-01

    Small-scale intellectualized medical instrument has attracted great attention in the field of biomedical engineering, and LabVIEW (Laboratory Virtual Instrument Engineering Workbench) provides a convenient environment for this application due to its inherent advantages. The principle and system structure of the hyperthermia instrument are presented. Type T thermocouples are employed as thermotransducers, whose amplifier consists of two stages, providing built-in ice point compensation and thus improving work stability over temperature. Control signals produced by specially designed circuit drive the programmable counter/timer 8254 chip to generate PWM (Pulse width modulation) wave, which is used as ultrasound radiation energy control signal. Subroutine design topics such as inner-tissue real time feedback temperature control algorithm, water temperature control in the ultrasound applicator are also described. In the cancer tissue temperature control subroutine, the authors exert new improvments to PID (Proportional Integral Differential) algorithm according to the specific demands of the system and achieve strict temperature control to the target tissue region. The system design and PID algorithm improvement have experimentally proved to be reliable and excellent, meeting the requirements of the hyperthermia system.

  14. Compact high voltage, high peak power, high frequency transformer for converter type modulator applications.

    PubMed

    Reghu, T; Mandloi, V; Shrivastava, Purushottam

    2016-04-01

    The design and development of a compact high voltage, high peak power, high frequency transformer for a converter type modulator of klystron amplifiers is presented. The transformer has been designed to operate at a frequency of 20 kHz and at a flux swing of ±0.6 T. Iron (Fe) based nanocrystalline material has been selected as a core for the construction of the transformer. The transformer employs a specially designed solid Teflon bobbin having 120 kV insulation for winding the high voltage secondary windings. The flux swing of the core has been experimentally found by plotting the hysteresis loop at actual operating conditions. Based on the design, a prototype transformer has been built which is per se a unique combination of high voltage, high frequency, and peak power specifications. The transformer was able to provide 58 kV (pk-pk) at the secondary with a peak power handling capability of 700 kVA. The transformation ratio was 1:17. The performance of the transformer is also presented and discussed.

  15. PIV measurements in a compact return diffuser under multi-conditions

    NASA Astrophysics Data System (ADS)

    Zhou, L.; Lu, W. G.; Shi, W. D.

    2013-12-01

    Due to the complex three-dimensional geometries of impellers and diffusers, their design is a delicate and difficult task. Slight change could lead to significant changes in hydraulic performance and internal flow structure. Conversely, the grasp of the pump's internal flow pattern could benefit from pump design improvement. The internal flow fields in a compact return diffuser have been investigated experimentally under multi-conditions. A special Particle Image Velocimetry (PIV) test rig is designed, and the two-dimensional PIV measurements are successfully conducted in the diffuser mid-plane to capture the complex flow patterns. The analysis of the obtained results has been focused on the flow structure in diffuser, especially under part-load conditions. The vortex and recirculation flow patterns in diffuser are captured and analysed accordingly. Strong flow separation and back flow appeared at the part-load flow rates. Under the design and over-load conditions, the flow fields in diffuser are uniform, and the flow separation and back flow appear at the part-load flow rates, strong back flow is captured at one diffuser passage under 0.2Qdes.

  16. 50 CFR 223.301 - Special rules-marine and anadromous fishes.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... section comprise a nonessential, experimental population (NEP). (2) Take of this species that is allowed... 50 CFR 223.203(a). (4) Geographic extent of the nonessential experimental population of Middle Columbia River steelhead. (i) The geographic range of this experimental population is all accessible...

  17. Effects of special composite stretching on the swing of amateur golf players

    PubMed Central

    Lee, Joong-chul; Lee, Sung-wan; Yeo, Yun-ghi; Park, Gi Duck

    2015-01-01

    [Purpose] The study investigated stretching for safer a golf swing compared to present stretching methods for proper swings in order to examine the effects of stretching exercises on golf swings. [Subjects] The subjects were 20 amateur golf club members who were divided into two groups: an experimental group which performed stretching, and a control group which did not. The subjects had no bone deformity, muscle weakness, muscle soreness, or neurological problems. [Methods] A swing analyzer and a ROM measuring instrument were used as the measuring tools. The swing analyzer was a GS400-golf hit ball analyzer (Korea) and the ROM measuring instrument was a goniometer (Korea). [Results] The experimental group showed a statistically significant improvement in driving distance. After the special stretching training for golf, a statistically significant difference in hit-ball direction deviation after swings were found between the groups. The experimental group showed statistically significant decreases in hit ball direction deviation. After the special stretching training for golf, statistically significant differences in hit-ball speed were found between the groups. The experimental group showed significant increases in hit-ball speed. [Conclusion] To examine the effects of a special stretching program for golf on golf swing-related factors, 20 male amateur golf club members performed a 12-week stretching training program. After the golf stretching training, statistically significant differences were found between the groups in hit-ball driving distance, direction deviation, deflection distance, and speed. PMID:25995553

  18. Effects of special composite stretching on the swing of amateur golf players.

    PubMed

    Lee, Joong-Chul; Lee, Sung-Wan; Yeo, Yun-Ghi; Park, Gi Duck

    2015-04-01

    [Purpose] The study investigated stretching for safer a golf swing compared to present stretching methods for proper swings in order to examine the effects of stretching exercises on golf swings. [Subjects] The subjects were 20 amateur golf club members who were divided into two groups: an experimental group which performed stretching, and a control group which did not. The subjects had no bone deformity, muscle weakness, muscle soreness, or neurological problems. [Methods] A swing analyzer and a ROM measuring instrument were used as the measuring tools. The swing analyzer was a GS400-golf hit ball analyzer (Korea) and the ROM measuring instrument was a goniometer (Korea). [Results] The experimental group showed a statistically significant improvement in driving distance. After the special stretching training for golf, a statistically significant difference in hit-ball direction deviation after swings were found between the groups. The experimental group showed statistically significant decreases in hit ball direction deviation. After the special stretching training for golf, statistically significant differences in hit-ball speed were found between the groups. The experimental group showed significant increases in hit-ball speed. [Conclusion] To examine the effects of a special stretching program for golf on golf swing-related factors, 20 male amateur golf club members performed a 12-week stretching training program. After the golf stretching training, statistically significant differences were found between the groups in hit-ball driving distance, direction deviation, deflection distance, and speed.

  19. Shuttle considerations for the design of large space structures

    NASA Technical Reports Server (NTRS)

    Roebuck, J. A., Jr.

    1980-01-01

    Shuttle related considerations (constraints and guidelines) are compiled for use by designers of a potential class of large space structures which are transported to orbit and, deployed, fabricated or assembled in space using the Space Shuttle Orbiter. Considerations of all phases of shuttle operations from launch to ground turnaround operations are presented. Design of large space structures includes design of special construction fixtures and support equipment, special stowage cradles or pallets, special checkout maintenance, and monitoring equipment, and planning for packaging into the orbiter of all additional provisions and supplies chargeable to payload. Checklists of design issues, Shuttle capabilities constraints and guidelines, as well as general explanatory material and references to source documents are included.

  20. 7 CFR 810.108 - Special grade designations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... Multiple special grade designations will be listed in alphabetical order. In the case of treated wheat, the official certificate shall show whether the wheat has been scoured, limed, washed, sulfured, or otherwise...

  1. 48 CFR 239.7409 - Special assembly.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Special assembly. 239.7409... Services 239.7409 Special assembly. (a) Special assembly is the designing, manufacturing, arranging... general use equipment. (b) Special assembly rates and charges shall be based on estimated costs. The...

  2. 48 CFR 239.7409 - Special assembly.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Special assembly. 239.7409... Services 239.7409 Special assembly. (a) Special assembly is the designing, manufacturing, arranging... general use equipment. (b) Special assembly rates and charges shall be based on estimated costs. The...

  3. 48 CFR 239.7409 - Special assembly.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Special assembly. 239.7409... Services 239.7409 Special assembly. (a) Special assembly is the designing, manufacturing, arranging... general use equipment. (b) Special assembly rates and charges shall be based on estimated costs. The...

  4. 48 CFR 239.7409 - Special assembly.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Special assembly. 239.7409... Services 239.7409 Special assembly. (a) Special assembly is the designing, manufacturing, arranging... general use equipment. (b) Special assembly rates and charges shall be based on estimated costs. The...

  5. 48 CFR 239.7409 - Special assembly.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Special assembly. 239.7409... Services 239.7409 Special assembly. (a) Special assembly is the designing, manufacturing, arranging... general use equipment. (b) Special assembly rates and charges shall be based on estimated costs. The...

  6. 76 FR 10476 - Special Conditions: Boeing Model 787-8 Airplane; Overhead Crew-Rest Compartment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-25

    ...\\ in interior volume, the design must ensure the ability to contain a fire likely to occur within the... or unusual design features associated with installation of an overhead crew-rest (OCR) compartment... this design feature. These special conditions contain the additional safety standards that the...

  7. 76 FR 65103 - Special Conditions: Gulfstream Aerospace Corporation, Model GIV-X Airplane; Aircraft Electronic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-20

    ... interior design configuration in the Gulfstream Model GIV-X passenger airplane. The Gulfstream Model GIV-X.... This airplane will have novel or unusual design features associated with the architecture and... appropriate safety standards for these design features. These special conditions contain the additional safety...

  8. Assistive Technology Design in Special Education. Issue Brief 2.

    ERIC Educational Resources Information Center

    Burnette, Jane

    The issue brief discusses technological principles, issues, and design features discovered or used by projects funded by the Office of Special Education Programs (OSEP). Information was obtained from interviews with project directors who were asked about their project experiences, the features and design principles essential to the success of…

  9. PERIGRAMMA--A System for the Support of People with Cognitive or Movement Impairments Working in Secretarial Positions.

    ERIC Educational Resources Information Center

    Destounis, Panagiotis; Garofalakis, John; Kondilis, Theodore; Mavritsakis, George; Rigou, Maria; Sirmakessis, Spiros; Tzimas, John

    In spite of the growing interest in interaction design, there remains a large user population that needs special interest: users with special needs. These users can dramatically benefit from software that better responds to their interaction needs, not to mention the fact that designing software that takes into account the special needs of such…

  10. Issues and Guidelines in Designing Follow-up Systems for Special Education Service Programs. Project Report Number 89-2.

    ERIC Educational Resources Information Center

    Bruininks, Robert H.; And Others

    This paper examines issues in designing post-school follow-up studies in special education. The examination focuses on survey research techniques, which are widely used in the investigation of post-school adjustment of former students with handicaps. In special education, survey research studies are used commonly to address many important…

  11. NASA Tech Briefs, March 1998. Volume 22, No. 3

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Topics include: special coverage of computer aided design and engineering, electronic components and circuits, electronic systems, physical sciences, materials, computer software, special coverage on mechanical technology, machinery/automation, manufacturing/fabrication, mathematics and information sciences, book and reports, and a special section of Electronics Tech Briefs. Profiles of the exhibitors at the National Design Engineering show are also included in this issue.

  12. 30 CFR 785.13 - Experimental practices mining.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... purposes, or to allow an alternative postmining land use, and may be undertaken if they are approved by the... accordance with the requirements of subchapter G of this chapter. (b) An application for an experimental... duration of the experimental practice, and any special monitoring which will be conducted; (2) How use of...

  13. 77 FR 64023 - Special Conditions: Airbus Model A318, A319, A320, and A321 Series Airplanes; Design Roll...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-18

    ... airplanes with modification 160023 (Sharklet). These airplanes will have novel or unusual design features..., A320, and A321 series airplanes because of a novel or unusual design feature, special conditions are... model that incorporates the same novel or unusual design feature, or should any other model already...

  14. Serial and parallel power equipment with high-temperature superconducting elements

    NASA Technical Reports Server (NTRS)

    Bencze, Laszlo; Goebl, Nandor; Palotas, Bela; Vajda, Istvan

    1995-01-01

    One of the prospective, practical applications of high-temperature superconductors is the fault-current limitation in electrical energy networks. The development and testing of experimental HTSC serial current limiters have been reported in the literature. A Hungarian electric power company has proposed the development of a parallel equipment for arc suppressing both in the industrial and customers' networks. On the basis of the company's proposal the authors have outlined the scheme of a compound circuit that can be applied both for current limitation and arc suppressing. In this paper the design principles and methods of the shunt equipment are presented. These principles involve the electrical, mechanical and cryogenic aspects with the special view on the electrical and mechanical connection between the HTSC material and the current lead. Preliminary experiments and tests have been carried out to demonstrate the validity of the design principles developed. The results of the experiments and of the technological investigations are presented.

  15. Mental exercising through simple socializing: social interaction promotes general cognitive functioning.

    PubMed

    Ybarra, Oscar; Burnstein, Eugene; Winkielman, Piotr; Keller, Matthew C; Manis, Melvin; Chan, Emily; Rodriguez, Joel

    2008-02-01

    Social interaction is a central feature of people's life and engages a variety of cognitive resources. Thus, social interaction should facilitate general cognitive functioning. Previous studies suggest such a link, but they used special populations (e.g., elderly with cognitive impairment), measured social interaction indirectly (e.g., via marital status), and only assessed effects of extended interaction in correlational designs. Here the relation between mental functioning and direct indicators of social interaction was examined in a younger and healthier population. Study 1 using survey methodology found a positive relationship between social interaction, assessed via amount of actual social contact, and cognitive functioning in people from three age groups including younger adults. Study 2 using an experimental design found that a small amount of social interaction (10 min) can facilitate cognitive performance. The findings are discussed in the context of the benefits social relationships have for so many aspects of people's lives.

  16. A versatile atomic force microscope integrated with a scanning electron microscope.

    PubMed

    Kreith, J; Strunz, T; Fantner, E J; Fantner, G E; Cordill, M J

    2017-05-01

    A versatile atomic force microscope (AFM), which can be installed in a scanning electron microscope (SEM), is introduced. The flexible design of the instrument enables correlated analysis for different experimental configurations, such as AFM imaging directly after nanoindentation in vacuum. In order to demonstrate the capabilities of the specially designed AFM installed inside a SEM, slip steps emanating around nanoindents in single crystalline brass were examined. This example showcases how the combination of AFM and SEM imaging can be utilized for quantitative dislocation analysis through the measurement of the slip step heights without the hindrance of oxide formation. Finally, an in situ nanoindentation technique is introduced, illustrating the use of AFM imaging during indentation experiments to examine plastic deformation occurring under the indenter tip. The mechanical indentation data are correlated to the SEM and AFM images to estimate the number of dislocations emitted to the surface.

  17. Active vibration attenuating seat suspension for an armored helicopter crew seat

    NASA Astrophysics Data System (ADS)

    Sztein, Pablo Javier

    An Active Vibration Attenuating Seat Suspension (AVASS) for an MH-60S helicopter crew seat is designed to protect the occupants from harmful whole-body vibration (WBV). Magnetorheological (MR) suspension units are designed, fabricated and installed in a helicopter crew seat. These MR isolators are built to work in series with existing Variable Load Energy Absorbers (VLEAs), have minimal increase in weight, and maintain crashworthiness for the seat system. Refinements are discussed, based on testing, to minimize friction observed in the system. These refinements include the addition of roller bearings to replace friction bearings in the existing seat. Additionally, semi-active control of the MR dampers is achieved using special purpose built custom electronics integrated into the seat system. Experimental testing shows that an MH-60S retrofitted with AVASS provides up to 70.65% more vibration attenuation than the existing seat configuration as well as up to 81.1% reduction in vibration from the floor.

  18. Development of a compact filament-discharge multi-cusp H- ion source.

    PubMed

    Jia, XianLu; Zhang, TianJue; Zheng, Xia; Qin, JiuChang

    2012-02-01

    A 14 MeV medical cyclotron with the external ion source has been designed and is being constructed at China Institute of Atomic Energy. The H(-) ion will be accelerated by this machine and the proton beam will be extracted by carbon strippers in dual opposite direction. The compact multi-cusp H(-) ion source has been developed for the cyclotron. The 79.5 mm long ion source is 48 mm in diameter, which is consisting of a special shape filament, ten columns of permanent magnets providing a multi-cusp field, and a three-electrode extraction system. So far, the 3 mA∕25 keV H(-) beam with an emittance of 0.3 π mm mrad has been obtained from the ion source. The paper gives the design details and the beam test results. Further experimental study is under way and an extracted beam of 5 mA is expected.

  19. The Effect of Propellant Variables on Slag in Subscale Spin Motors. Part 1; Design and Qualification of a Slag Discrimination Motor

    NASA Technical Reports Server (NTRS)

    Perkins, F. M.; Beus, R. W.; May, D. H.

    1995-01-01

    The formation, collection, and expulsion of aluminum oxide slag is known to affect the performance of many solid rocket motor systems. Slag expulsion, in particular, is believed to be capable of causing pressure and thrust perturbations. Propellant combustion studies, performed and documented by many investigators, have shown that variations in propellant raw materials and processing affect the nature of alumina droplets at the burning propellant surface, and hence, may affect the quantity of slag retained in the motor chamber, available for expulsion. Thiokol has completed an experimental and analytical evaluation to determine the effects of several material and process variables on Space SHuttle propellant and its propensity to 'slag'. This paper describes the test article, a small scale spin motor with special nozzle, designed and qualified as a slag discriminating tool for use in the evaluation.

  20. Sector and Sphere: the design and implementation of a high-performance data cloud

    PubMed Central

    Gu, Yunhong; Grossman, Robert L.

    2009-01-01

    Cloud computing has demonstrated that processing very large datasets over commodity clusters can be done simply, given the right programming model and infrastructure. In this paper, we describe the design and implementation of the Sector storage cloud and the Sphere compute cloud. By contrast with the existing storage and compute clouds, Sector can manage data not only within a data centre, but also across geographically distributed data centres. Similarly, the Sphere compute cloud supports user-defined functions (UDFs) over data both within and across data centres. As a special case, MapReduce-style programming can be implemented in Sphere by using a Map UDF followed by a Reduce UDF. We describe some experimental studies comparing Sector/Sphere and Hadoop using the Terasort benchmark. In these studies, Sector is approximately twice as fast as Hadoop. Sector/Sphere is open source. PMID:19451100

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