Ethical considerations in malaria research proposal review: empirical evidence from 114 proposals submitted to an Ethics Committee in Thailand.

PubMed

Adams, Pornpimon; Prakobtham, Sukanya; Limphattharacharoen, Chanthima; Vutikes, Pitchapa; Khusmith, Srisin; Pengsaa, Krisana; Wilairatana, Polrat; Kaewkungwal, Jaranit

2015-09-14

Malaria research is typically conducted in developing countries in areas of endemic disease. This raises specific ethical issues, including those related to local cultural concepts of health and disease, the educational background of study subjects, and principles of justice at the community and country level. Research Ethics Committees (RECs) are responsible for regulating the ethical conduct of research, but questions have been raised whether RECs facilitate or impede research, and about the quality of REC review itself. This study examines the review process for malaria research proposals submitted to the Ethics Committee of the Faculty of Tropical Medicine at Mahidol University, Thailand. Proposals for all studies submitted for review from January 2010 to December 2014 were included. Individual REC members' reviewing forms were evaluated. Ethical issues (e.g., scientific merit, risk-benefit, sample size, or informed-consent) raised in the forms were counted and analysed according to characteristics, including study classification/design, use of specimens, study site, and study population. All 114 proposals submitted during the study period were analysed, comprising biomedical studies (17 %), drug trials (13 %), laboratory studies (24 %) and epidemiological studies (46 %). They included multi-site (13 %) and international studies (4 %), and those involving minority populations (28 %), children (17 %) and pregnant women (7 %). Drug trials had the highest proportion of questions raised for most ethical issues, while issues concerning privacy and confidentiality tended to be highest for laboratory and epidemiology studies. Clarifications on ethical issues were requested by the ethics committee more for proposals involving new specimen collection. Studies involving stored data and specimens tended to attract more issues around privacy and confidentiality. Proposals involving minority populations were more likely to raise issues than those that did not. Those involving vulnerable populations were more likely to attract concerns related to study rationale and design. This study stratified ethical issues raised in a broad spectrum of research proposals. The Faculty of Tropical Medicine at Mahidol University is a significant contributor to global malaria research output. The findings shed light on the ethical review process that may be useful for stakeholders, including researchers, RECs and sponsors, conducting malaria research in other endemic settings.

36 CFR 242.20 - Request for reconsideration.

Code of Federal Regulations, 2010 CFR

2010-07-01

... statement of the facts of the dispute, the issues raised by the request, and specific references to any law... implement a final decision on a request for reconsideration after compliance with 5 U.S.C. 551-559 (APA). (g...

Space station: The role of software

NASA Technical Reports Server (NTRS)

Hall, D.

1985-01-01

Software will play a critical role throughout the Space Station Program. This presentation sets the stage and prompts participant interaction at the Software Issues Forum. The presentation is structured into three major topics: (1) an overview of the concept and status of the Space Station Program; (2) several charts designed to lay out the scope and role of software; and (3) information addressing the four specific areas selected for focus at the forum, specifically: software management, the software development environment, languages, and standards. NASA's current thinking is highlighted and some of the relevant critical issues are raised.

5 CFR 2422.31 - Application for review of a Regional Director Decision and Order.

Code of Federal Regulations, 2012 CFR

2012-01-01

... specify the matters and rulings to which exception(s) is taken, include a summary of evidence relating to any issue raised in the application, and make specific reference to page citations in the transcript...

5 CFR 2422.31 - Application for review of a Regional Director Decision and Order.

Code of Federal Regulations, 2011 CFR

2011-01-01

... specify the matters and rulings to which exception(s) is taken, include a summary of evidence relating to any issue raised in the application, and make specific reference to page citations in the transcript...

Surgical ethics and the challenge of surgical innovation.

PubMed

Angelos, Peter

2014-12-01

Surgical ethics as a specific discipline is relatively new to many. Surgical ethics focuses on the ethical issues that are particularly important to the care of surgical patients. Informed consent for surgical procedures, the level of responsibility that surgeons feel for their patients' outcomes, and the management of surgical innovation are specific issues that are important in surgical ethics and are different from other areas of medicine. The future of surgical progress is dependent on surgical innovation, yet the nature of surgical innovation raises specific concerns that challenge the professionalism of surgeons. These concerns will be considered in the following pages. Copyright © 2014 Elsevier Inc. All rights reserved.

77 FR 56421 - Standards of Performance for Petroleum Refineries; Standards of Performance for Petroleum...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

...On June 24, 2008, the EPA promulgated amendments to the Standards of Performance for Petroleum Refineries and new standards of performance for petroleum refinery process units constructed, reconstructed or modified after May 14, 2007. The EPA subsequently received three petitions for reconsideration of these final rules. On September 26, 2008, the EPA granted reconsideration and issued a stay for the issues raised in the petitions regarding process heaters and flares. On December 22, 2008, the EPA addressed those specific issues by proposing amendments to certain provisions for process heaters and flares and extending the stay of these provisions until further notice. The EPA also proposed technical corrections to the rules for issues that were raised in the petitions for reconsideration. In this action, the EPA is finalizing those amendments and technical corrections and is lifting the stay of all the provisions granted on September 26, 2008 and extended until further notice on December 22, 2008.

Corporate Funding for Schools of Public Health: Confronting the Ethical and Economic Challenges.

PubMed

Bayer, Ronald; Sampat, Bhaven N

2016-04-01

We discuss the public and private sponsoring of university research and the issues it raises in a context of diminished federal funding. We consider research funding at schools of public health and why these schools have historically had weaker links to industry than have other academic units. We argue that the possibility of enhanced links with industry at schools of public health may raise specific concerns beyond those facing universities generally. Six issues should be considered before entering into these relationships: (1) the effects on research orientation, (2) unacceptability of some funders, (3) potential threats to objectivity and academic freedom, (4) effects on academic standards, (5) the effects on dissemination of knowledge, and (6) reputational risks.

On Forests and Trees: A Response to Klingner.

ERIC Educational Resources Information Center

Neuman, Susan B.; Koskinen, Patricia

1993-01-01

Responds to criticisms raised in another article in this issue concerning a study of incidental word learning among second-language learners viewing captioned television. Suggests that the criticisms fail to "see the forest for the trees." Responds to specific methodological criticisms. (RS)

Transnational Threats: Blending Law Enforcement and Military Strategies

DTIC Science & Technology

2000-11-01

Providing Humanitarian Assistance Following NBC Accidents/Incidents: The Legal Considerations, Colorado Springs, CO: Institute for National Security Studies...draft of a position on cyber crime .36 The draft focused on such issues as extradition, mutual legal assistance, and trans-border computer searches. These...warfare also raises specific legal issues related to computer crime : what is a crime , who commits it, and what does the law say about it? 21. A

Raising Sensitive Issues in a Team

ERIC Educational Resources Information Center

Lindoerfer, Dennis

2008-01-01

Have you ever wondered how to deal with a sensitive issue within your team? For example, how do you raise the issue that the women rarely get listened to? How do you bring up your observation that the team members from Marketing always dominate the meetings? This guidebook focuses on ways to determine whether to raise such an issue in a team…

Electronic Manipulation Endangers Credibility.

ERIC Educational Resources Information Center

Schaub, Laura

1998-01-01

Argues that technological advances with digital photo enhancement computer programs raise serious questions concerning ethics in student publications, and that instructors and advisers have an obligation to teach students about the appropriate, ethical use of these programs. Outlines specific issues and reminds students that it is wrong to enhance…

5 CFR 2422.31 - When do you file an application for review of a Regional Director Decision and Order?

Code of Federal Regulations, 2013 CFR

2013-01-01

... rulings to which exception(s) is taken, include a summary of evidence relating to any issue raised in the application, and make specific references to page citations in the transcript if a hearing was held. An...

5 CFR 2422.31 - When do you file an application for review of a Regional Director Decision and Order?

Code of Federal Regulations, 2014 CFR

2014-01-01

... rulings to which exception(s) is taken, include a summary of evidence relating to any issue raised in the application, and make specific references to page citations in the transcript if a hearing was held. An...

Interpreters, Interpreting, and the Study of Bilingualism.

ERIC Educational Resources Information Center

Valdes, Guadalupe; Angelelli, Claudia

2003-01-01

Discusses research on interpreting focused specifically on issues raised by this literature about the nature of bilingualism. Suggests research carried out on interpreting--while primarily produced with a professional audience in mind and concerned with improving the practice of interpreting--provides valuable insights about complex aspects of…

7 CFR 1415.8 - Establishing priority for enrollment of properties.

Code of Federal Regulations, 2010 CFR

2010-01-01

... conversion to uses other than grazing; (3) Plant and animal biodiversity; and (4) In ranking parcels offered... Directors may establish separate ranking pools to address, for example, specific conservation issues raised by State, regional, and national conservation priorities. (f) The NRCS State Conservationist and FSA...

Reinforcement and Induction of Operant Variability

ERIC Educational Resources Information Center

Neuringer, Allen

2012-01-01

The target paper by Barba (2012) raises issues that were the focus of the author's first two publications on operant variability. The author will describe the main findings in those papers and then discuss Barba's specific arguments. Barba has argued against the operant nature of variability. (Contains 2 figures.)

Someone at School Has AIDS. 2001 Edition.

ERIC Educational Resources Information Center

Fraser, Katherine; Bogden, James F.

This policy guide explains that every state and school district needs policies addressing serious issues raised by human immunodeficiency virus (HIV) infection. Chapter 1, "Developing Policy," discusses why policies are valuable, at what level policy belongs, and whether policies should be specific to HIV. Chapter 2, "Policy…

The Difficult Pursuit of Truth: A Response to Kai Horsthemke

ERIC Educational Resources Information Center

Godon, Rafal

2017-01-01

In this article, Rafal Godon responds to Kai Horsthemke's article (this issue), "Inclusive Education and 'Barrierefreiheit': Some Social-Epistemological Considerations" (EJ1130978). The question raised by Kai Horsthemke, Godon says, draws readers' attention to a very specific aspect of the conference theme, "Philosophy as…

War, Terrorism, and Children

ERIC Educational Resources Information Center

DeRanieri, Joseph T.; Clements, Paul T.; Clark, Kathleen; Kuhn, Douglas Wolcik; Manno, Martin S.

2004-01-01

Many caregivers are encountering the issue of communicating with children and adolescents about current world events, specifically war and terrorism. As health care providers, it is important to raise awareness of how children may understand, interpret, and respond to related fears and concerns. Although honesty and reassurance are clearly the…

Resettlement: A Cultural and Psychological Crisis.

ERIC Educational Resources Information Center

Hulewat, Phyllis

1996-01-01

The stages of resettlement and need to integrate past cultural experience into their new life are similar for all immigrants. Describes stages of resettlement and basic elements needed to manage the resettlement process. Three specific groups of clients are identified, and case management methods are presented for dealing with issues raised by…

Space transfer concepts and analyses for exploration missions: Technical directive 10

NASA Technical Reports Server (NTRS)

Woodcock, Gordon R.

1992-01-01

The current technical effort is part of the third phase of a broad-scoped and systematic study of space transfer concepts for human lunar and Mars missions. The study addressed issues that were raised during the previous phases but specifically on launch vehicle size trades and MEV options.

Sheltered and Supported Work Comparison: A Response to Wehman's Comments.

ERIC Educational Resources Information Center

Lam, Chow S.

1987-01-01

Responds to comments made by Wehman, Hill, Kregel, and Moon (1987) concerning the results of Lam's 1986 study comparing supported and sheltered employment programs for persons with mental retardation. Addresses specific questions raised by Wehman and his colleagues and discusses research issues on sample comparability. (Author/NB)

Having and Raising Children: Unconventional Families, Hard Choices, and the Social Good.

ERIC Educational Resources Information Center

Narayan, Uma, Ed.; Bartkowiak, Julia J., Ed.

Noting that the term "family values" has achieved prominence in the rhetoric of political debate, this book compiles essays by philosophers, political scientists, and legal scholars exploring specific issues within the legal, ethical, and political dimensions of familial relationships. Collectively, the essays point out that many…

Harvesting the Ocean: 1. The Ocean.

ERIC Educational Resources Information Center

Caton, Albert, Ed.; And Others

This booklet is the first in a series of three interdisciplinary units which focus specifically on the Pacific Ocean and its surrounding countries. The booklet, designed for lower secondary students, provides an introduction to the ocean environment such that students can understand the physical factors underlying issues raised by the other two…

IQ--It's All in the Family.

ERIC Educational Resources Information Center

Miller, Phyllis, Ed.

1999-01-01

This issue of a research journal on gifted education examines a number of research projects that delve into questions of how family life affects intelligence, especially among gifted children. Specific articles include: (1) "Are We Raising Smarter Children Today?" (Wendy M. Williams), which discusses the effects of school-related factors…

How to investigate neuro-biochemical relationships on a regional level in humans? Methodological considerations for combining functional with biochemical imaging.

PubMed

Duncan, Niall W; Wiebking, Christine; Muñoz-Torres, Zeidy; Northoff, Georg

2014-01-15

There is an increasing interest in combining different imaging modalities to investigate the relationship between neural and biochemical activity. More specifically, imaging techniques like MRS and PET that allow for biochemical measurement are combined with techniques like fMRI and EEG that measure neural activity in different states. Such combination of neural and biochemical measures raises not only technical issues, such as merging the different data sets, but also several methodological issues. These methodological issues – ranging from hypothesis generation and hypothesis-guided use of technical facilities to target measures and experimental measures – are the focus of this paper. We discuss the various methodological problems and issues raised by the combination of different imaging methodologies in order to investigate neuro-biochemical relationships on a regional level in humans. For example, the choice of transmitter and scan type is discussed, along with approaches to allow the establishment of particular specificities (such as regional or biochemical) to in turn make results fully interpretable. An algorithm that can be used as a form of checklist for designing such multimodal studies is presented. The paper concludes that while several methodological and technical caveats needs to be overcome and addressed, multimodal imaging of the neuro-biochemical relationship provides an important tool to better understand the physiological mechanisms of the human brain.

How to investigate neuro-biochemical relationships on a regional level in humans? Methodological considerations for combining functional with biochemical imaging.

PubMed

Duncan, Niall W; Wiebking, Christine; Munoz-Torres, Zeidy; Northoff, Georg

2013-10-25

There is an increasing interest in combining different imaging modalities to investigate the relationship between neural and biochemical activity. More specifically, imaging techniques like MRS and PET that allow for biochemical measurement are combined with techniques like fMRI and EEG that measure neural activity in different states. Such combination of neural and biochemical measures raises not only technical issues, such as merging the different data sets, but also several methodological issues. These methodological issues - ranging from hypothesis generation and hypothesis-guided use of technical facilities to target measures and experimental measures - are the focus of this paper. We discuss the various methodological problems and issues raised by the combination of different imaging methodologies in order to investigate neuro-biochemical relationships on a regional level in humans. For example, the choice of transmitter and scan type is discussed, along with approaches to allow the establishment of particular specificities (such as regional or biochemical) to in turn make results fully interpretable. An algorithm that can be used as a form of checklist for designing such multimodal studies is presented. The paper concludes that while several methodological and technical caveats needs to be overcome and addressed, multimodal imaging of the neuro-biochemical relationship provides an important tool to better understand the physiological mechanisms of the human brain. Copyright © 2013. Published by Elsevier B.V.

Human-animal chimera: a neuro driven discussion? Comparison of three leading European research countries.

PubMed

Cabrera Trujillo, Laura Yenisa; Engel-Glatter, Sabrina

2015-06-01

Research with human-animal chimera raises a number of ethical concerns, especially when neural stem cells are transplanted into the brains of non-human primates (NHPs). Besides animal welfare concerns and ethical issues associated with the use of embryonic stem cells, the research is also regarded as controversial from the standpoint of NHPs developing cognitive or behavioural capabilities that are regarded as "unique" to humans. However, scientists are urging to test new therapeutic approaches for neurological diseases in primate models as they better mimic human physiology than all current animal models. As a response, various countries have issued reports on the topic. Our paper summarizes the ethical issues raised by research with human-animal brain chimeras and compares the relevant regulatory instruments and different recommendations issued in national reports from three important European research nations: Germany, Switzerland and the United Kingdom. We assess and discuss the focus and priorities set by the different reports, review various reasons for and perspectives on the importance of the brain in chimera research, and identify critical points in the reports that warrant further specification and debate.

The Campus Green: Fund Raising in Higher Education. ERIC Digest.

ERIC Educational Resources Information Center

Brittingham, Barbara E.; Pezzullo, Thomas R.

This digest summarizes issues raised in a research report on fund raising in higher education. The following questions are addressed: What are the changes and trends since the early days of educational fund raising? What are the implications? What is known about spending? What is known about donor behavior? What are the major ethical issues? What…

Newspaper reporting on child raising in Japan.

PubMed

Basnet, Narayan Bahadur; Kato, Hitoshi; Nakamura, Yoshihiro; Watanabe, Hiroshi; Igarashi, Takashi

2004-04-01

Study of child-raising issues published in newspapers is lacking. The purpose of this article is to determine the spectrum of issues associated with child raising based on a newspaper. We conducted a cross-sectional study of items related to children (aged <19 years) reported in a Japanese newspaper from July 1, 2001, to June 30, 2002. A total of 1287 child-related items were published. The percentages of reports regarding individual health, health-related issues, topics on two or more issues, and global child issues were 5.9%, 28.8%, 62.9%, and 2.4%, respectively. The most common singly reported issues from 446 items were on child play and recreation, welfare activities, security, child abuse, child death, sports, and parenting. These reports assist parents, families, nurses, pediatricians, and child care workers in providing information on healthy child raising.

77 FR 52553 - Standards of Performance for Stationary Gas Turbines; Standards of Performance for Stationary...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-29

...The EPA is proposing to amend the new source performance standards (NSPS) for stationary gas turbines and stationary combustion turbines. These amendments are primarily in response to issues raised by the regulated community. On July 6, 2006, the EPA promulgated amendments to the new source performance standards for stationary combustion turbines. On September 5, 2006, the Utility Air Regulatory Group filed a petition for reconsideration of certain aspects of the promulgated standards. The EPA is proposing to amend specific provisions in the NSPS to resolve issues and questions raised by the petition for reconsideration, and to address other technical and editorial issues. In addition, this proposed rule would amend the location and wording of existing paragraphs for clarity. The proposed amendments would increase the environmental benefits of the existing requirements because the emission standards would apply at all times. The proposed amendments would also promote efficiency by recognizing the environmental benefit of combined heat and power and the beneficial use of low energy content gases.

Advanced Donation Programs and Deceased Donor-Initiated Chains-2 Innovations in Kidney Paired Donation.

PubMed

Wall, Anji E; Veale, Jeffrey L; Melcher, Marc L

2017-12-01

Kidney paired donation (KPD) strategies have facilitated compatible living-donor kidney transplants for end-stage renal disease patients with willing but incompatible living donors. Success has inspired further innovations that expand opportunities for kidney-paired donation. Two such innovations are the advanced donation strategy in which a donor provides a kidney before their recipient is matched, or even in need of, a kidney transplant, and deceased donor initiated chains in which chains are started with deceased donors rather than altruistic living donors. Although these innovations may expand KPD, they raise several ethical issues. Specific concerns raised by advanced donation include the management of uncertainty, the extent of donor and recipient consent, the scope of the obligation that the organization has to the kidney exchange paired recipient, the naming of alternative recipients, and the potential to unfairly advantage the recipient. Use of deceased donors for chain-initiating kidneys raises ethical issues concerning the consent process for each involved party, the prioritization of deceased donor kidneys, the allocation of chain ending kidneys, and the value of a living donor kidney versus a deceased donor kidney. We outline each ethical issue and discuss how it can be conceptualized and managed so that these KPD innovations programs are ultimately successful.

Intra-Family Gamete Donation: A Solution to Concerns Regarding Gamete Donation in China?

PubMed

Liao, Juhong; Devolder, Katrien

2016-09-01

Gamete donation from third parties is controversial in China as it severs blood ties, which are considered of utmost importance in Confucian tradition. In recent years, infertile couples are increasingly demonstrating a preference for the use of gametes donated by family members to conceive children-known as "intra-family gamete donation." The main advantage of intra-family gamete donation is that it maintains blood ties between children and both parents. To date there is no practice of intra-family gamete donation in China. In this paper, we investigate intra-family adoption in China in order to illustrate that intra-family gamete donation is consistent with Confucian tradition regarding the importance of maintaining blood ties within the family. There are several specific ethical issues raised by intra-family gamete donation. It may, for example, result in consanguinity and the semblance of incest, lead to confused family relationships, and raise concerns about possible coercion of familial donors. Confucian tradition provides a new approach to understand and deal with these ethical issues in a way that Western tradition does not. As a result, we suggest intra-family gamete donation could be an acceptable solution to the problem of infertility in China. However, further discussion and open debates on the ethical issues raised by intra-family gamete donation are needed in China.

Nutrition labelling is a trade policy issue: lessons from an analysis of specific trade concerns at the World Trade Organization.

PubMed

Thow, Anne Marie; Jones, Alexandra; Hawkes, Corinna; Ali, Iqra; Labonté, Ronald

2017-01-12

Interpretive nutrition labels provide simplified nutrient-specific text and/or symbols on the front of pre-packaged foods, to encourage and enable consumers to make healthier choices. This type of labelling has been proposed as part of a comprehensive policy response to the global epidemic of non-communicable diseases. However, regulation of nutrition labelling falls under the remit of not just the health sector but also trade. Specific Trade Concerns have been raised at the World Trade Organization's Technical Barriers to Trade Committee regarding interpretive nutrition labelling initiatives in Thailand, Chile, Indonesia, Peru and Ecuador. This paper presents an analysis of the discussions of these concerns. Although nutrition labelling was identified as a legitimate policy objective, queries were raised regarding the justification of the specific labelling measures proposed, and the scientific evidence for effectiveness of such measures. Concerns were also raised regarding the consistency of the measures with international standards. Drawing on policy learning theory, we identified four lessons for public health policy makers, including: strategic framing of nutrition labelling policy objectives; pro-active policy engagement between trade and health to identify potential trade issues; identifying ways to minimize potential 'practical' trade concerns; and engagement with the Codex Alimentarius Commission to develop international guidance on interpretative labelling. This analysis indicates that while there is potential for trade sector concerns to stifle innovation in nutrition labelling policy, care in how interpretive nutrition labelling measures are crafted in light of trade commitments can minimize such a risk and help ensure that trade policy is coherent with nutrition action. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

The effect of leader communication style on safety-conscious work environments at domestic nuclear power plants

NASA Astrophysics Data System (ADS)

Goldberg, Edward Michael

Public risk from unsafe nuclear power plant operations increases when plant workers are reluctant to raise issues and concerns. The effect of leader communication style on the safety-conscious work environment (SCWE) at domestic nuclear power plants was evaluated using a descriptive quantitative research study. A sample of 379 plant employees was surveyed to determine leader communication style elements that foster SCWE. The results reveal that leader communication style significantly affects a safety-conscious work environment. Specific attributes such as wit, articulation, self-disclosure, and social composure, confirmation, and experience, were proven to directly affect worker's likelihood to raise issues and concerns. The direct effect of leader, communication style on safe plant operations and the communication actions leaders can take to improve the safety of those operations is discussed.

Accounting guidelines for HMOs: issues and practices.

PubMed

Ingram, R W; Robbins, W A

1987-03-01

HMOs are fast becoming an important part of the healthcare industry today. Unfortunately, specific accounting guidelines have not yet been established for them. This concern has led the AICPA to describe and offer recommendations concerning preferred accounting techniques for HMOs. This article looks at the issues raised by the AICPA and how current HMO financial officers feel about the practices that are recommended. It is suggested that the organization, taxability, and other attributes of an HMO must be clearly understood before strict accounting guidelines are imposed.

Researching Social Capital in Education: Some Conceptual Considerations Relating to the Contribution of Network Analysis

ERIC Educational Resources Information Center

Lee, Moosung

2010-01-01

This article discusses conceptual considerations for social capital research in education from a social network perspective. Specifically, the article raises three key conceptual issues that call for further elaboration of concepts of social capital: redefining potential resources as accessible but un-utilized sources of social capital;…

Before You Decide: What Families Would Like Policy Makers to Know.

ERIC Educational Resources Information Center

Clark, Marsha J.; Kendrick, Martie; Chamberlain, Linda; Chesley, Esther; Clement, Stacie; Cummings, Dawn; Henri-Mackenzie, Sue; Labbe, Tonya; MacDonald, Janice; McNally, Diana; Niles, Nancy; Raymond, Roberta; Russell, Candice

This booklet, developed by parents of children with developmental disabilities, is intended to help policy makers understand major parental concerns about raising a child with a disability. The specific issues addressed are: (1) the special needs of families with a disabled child; (2) the right to community integration; (3) the continuing…

The Disabled Student Experience: Does the SERVQUAL Scale Measure Up?

ERIC Educational Resources Information Center

Vaughan, Elizabeth; Woodruffe-Burton, Helen

2011-01-01

Purpose: The purpose of this paper is to empirically test a new disabled service user-specific service quality model ARCHSECRET against a modified SERVQUAL model in the context of disabled students within higher education. Design/methodology/approach: The application of SERVQUAL in the voluntary sector had raised serious issues on its portability…

Raising the Bar: Using Coaching Conversations to Address Issues of Low Expectations for Students in Urban Settings

ERIC Educational Resources Information Center

Ramkellawan, Reshma; Bell, Jacobe

2017-01-01

Two instructional coaches explore the effectiveness of targeted coaching conversations to address teachers' perceptions of their students' capacities. In this study, the researchers focus on how specific questions can promote teachers' metacognition of underlying biases held toward their students. Researchers also explore the implications for…

Measuring the Child Quality of Life: Issues and Options.

ERIC Educational Resources Information Center

Arboleda, Jairo; Levinger, Beryl

A Child Quality of Life Index (CQLI) should be developed in order to realize three objectives: (1) to raise the consciousness of decision makers, prospective donors, field workers, and community members concerning the needs of children; (2) to assist field workers and community members in planning specific programs to meet the priority needs of…

Problems with a Play Paradigm: A Reply to Dansky.

ERIC Educational Resources Information Center

Simon, Tony; Smith, Peter K.

1986-01-01

In answer to points raised by Dansky (1985) about specific inferences from Simon and Smith's study (1985) and broader issues about a single-session paradigm used in play and problem solving studies, Simon and Smith argue that their study adequately demonstrated how methodological factors in paradigm can swamp the effects of any treatment…

75 FR 60671 - Rules of Adjudication and Enforcement

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-01

... cover letter stating the nature of the commenter's interest in the proposed rulemaking. All comments... against specific individuals or entities. 44 U.S.C. 3518(c)(1)(B)(ii). Subpart C--Pleadings Sections 210... on the existence and nature of any public interest issues raised by the complaint at the time of its...

Chocolate and cardiovascular health: is it too good to be true?

PubMed

Ariefdjohan, Merlin W; Savaiano, Dennis A

2005-12-01

Recent findings indicate that cocoa and chocolate, when processed appropriately, may contain relatively large amounts of flavonoids, particularly catechin and epicatechin. We review the benefits of these flavonoids, specifically with regard to cardiovascular health, and raise several unresolved issues that suggest the need for additional research and product development in this area.

Illicit drugs, testing, prevention and work in France: ethical and legal issues.

PubMed

Fantoni-Quinton, Sophie; Bossu, Bernard; Morgenroth, Thomas; Frimat, Paul

2010-09-01

The use of illicit drugs in the workplace raises issues pertaining to prevention and safety and the responsibility of the various members of staff. It also brings into question the interface between work and private life. If employees are in theory responsible for their own safety and risk heavy penalties in the event of the consumption of illicit drugs in the workplace, such behaviour has to be proved. In reality, the worker can only be partially and marginally held liable, given the fact that the employer is prohibited from infringing on their rights and liberties (restrictions on the searching of their personal belongings and lockers as well as on the carrying out of breath testing and saliva testing under restrictive conditions). Employers have for their part a broader range of responsibilities and, above all, an absolute obligation to achieve specific goals in terms of health and safety resulting in the need to take action. In accordance with the International Labour Organization recommendations, European and national legislation, the employer has to implement a suitable preventive policy. However, where is the balance between prevention and repression? Very few studies have raised these issues and our aim is to precisely situate the place of drug testing in the employer's repressive arsenal in France and to try to answer the legal and ethical issues raised. Thus, for example, repression can only be acceptable when it deals with moderate and non-addicted users, or it could be tantamount to discrimination.

Does uncontrolled cardiac death for organ donation raise ethical questions? An opinion survey.

PubMed

Goudet, V; Albouy-Llaty, M; Migeot, V; Pain, B; Dayhot-Fizelier, C; Pinsard, M; Gil, R; Beloucif, S; Robert, R

2013-11-01

Organ donation after uncontrolled cardiac death raises complex ethical issues. We conducted a survey in a large hospital staff population, including caregivers and administrators, to determine their ethical viewpoints regarding organ donation after uncontrolled cardiac death. Multicenter observational survey using a questionnaire, including information on the practical modalities of the procedure. Respondents were asked to answer 15 detailed ethical questions corresponding to different ethical issues raised in the literature. Ethical concerns was defined when respondents expressed ethical concerns in their answers to at least three of nine specifically selected ethical questions. One thousand one hundred ninety-six questionnaires were received, and 1057 could be analysed. According to our definition, 573 respondents out of 1057 (54%) had ethical concerns with regard to donation after cardiac death and 484 (46 %) had no ethical concerns. Physicians (55%) and particularly junior intensivists (65%) tended to have more ethical issues than nurses (52%) and hospital managers (37%). Junior intensivists had more ethical issues than senior intensivists (59%), emergency room physicians (46%) and transplant specialists (43%). Only 46% of hospital-based caregivers and managers appear to accept easily the legitimacy of organ donation after cardiac death. A significant number of respondents especially intensivists, expressed concerns over the dilemma between the interests of the individual and those of society. These results underline the need to better inform both healthcare professionals and the general population to help to the development of such procedure. © 2013 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

Genetic testing and genomic analysis: a debate on ethical, social and legal issues in the Arab world with a focus on Qatar.

PubMed

El Shanti, Hatem; Chouchane, Lotfi; Badii, Ramin; Gallouzi, Imed Eddine; Gasparini, Paolo

2015-11-14

In 2013 both Saudi Arabia and Qatar launched genome projects with the aim of providing information for better diagnosis, treatment and prevention of diseases and, ultimately to realize personalized medicine by sequencing hundred thousands samples. These population based genome activities raise a series of relevant ethical, legal and social issues general, related to the specific population structure as well as to the Islamic perspective on genomic analysis and genetic testing. To contribute to the debate, the Authors after reviewing the existing literature and taking advantage of their professional experience in the field and in the geographic area, discuss and provide their opinions. In particular, the Authors focus on the impact of consanguinity on population structure and disease frequency in the Arab world, on genetic testing and genomic analysis (i.e. technical aspects, impact, etc.) and on their regulations. A comparison between the Islamic perspective and the ethical, social and legal issues raised in other population contexts is also carried. In conclusion, this opinion article with an up-to-date contribution to the discussion on the relevance and impact of genomic analysis and genetic testing in the Arab world, might help in producing specific national guidelines on genetic testing and genomic analysis and help accelerate the implementation and roll out of genome projects in Muslim countries and more specifically in Qatar, and other countries of the Gulf.

Architectural Optimization of Digital Libraries

NASA Technical Reports Server (NTRS)

Biser, Aileen O.

1998-01-01

This work investigates performance and scaling issues relevant to large scale distributed digital libraries. Presently, performance and scaling studies focus on specific implementations of production or prototype digital libraries. Although useful information is gained to aid these designers and other researchers with insights to performance and scaling issues, the broader issues relevant to very large scale distributed libraries are not addressed. Specifically, no current studies look at the extreme or worst case possibilities in digital library implementations. A survey of digital library research issues is presented. Scaling and performance issues are mentioned frequently in the digital library literature but are generally not the focus of much of the current research. In this thesis a model for a Generic Distributed Digital Library (GDDL) and nine cases of typical user activities are defined. This model is used to facilitate some basic analysis of scaling issues. Specifically, the calculation of Internet traffic generated for different configurations of the study parameters and an estimate of the future bandwidth needed for a large scale distributed digital library implementation. This analysis demonstrates the potential impact a future distributed digital library implementation would have on the Internet traffic load and raises questions concerning the architecture decisions being made for future distributed digital library designs.

Issues and Dilemmas in Sexual Treatment

ERIC Educational Resources Information Center

Lassen, Carol L.

1976-01-01

This paper raises issues and questions which repeatedly confront the sex therapist rather than the patient. Issues raised are: conflict in values; the impotent male; masturbation; nonorgasmic females; and the philosophical approach to therapy of women therapists influenced by the women's movement. (NG)

Ethical and Legal Issues in Biobanking for Genomic Research in Nigeria

PubMed Central

Akintola, Simisola. O.

2013-01-01

The pursuit of genomic research and biobanking has raised concerns and discussions about the ethical and legal implications. Given the specific challenges that surround such enterprise in low and middle income countries, it is pertinent to examine them in the light of the advent of Biobanking and Genomic research in Nigeria. In this paper I discuss the issues and suggest model solutions derived from advanced jurisdictions. These ethical and legal issues are discussed within the context of the legal system of a typical African country whose jurisprudence derives from that of its erstwhile colonial master, the United Kingdom. This includes issues relating to law and human rights, informed consent, native and customary law. PMID:24353984

29 CFR 1955.5 - Petitions for withdrawal of approval.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION... petition for public comment; (ii) Holding informal discussion on the issues raised by the petition with the... future action on those issues or any other issues raised regarding a State plan. ...

Balancing Ethical Pros and Cons of Stem Cell Derived Gametes.

PubMed

Segers, Seppe; Mertes, Heidi; de Wert, Guido; Dondorp, Wybo; Pennings, Guido

2017-07-01

In this review we aim to provide an overview of the most important ethical pros and cons of stem cell derived gametes (SCD-gametes), as a contribution to the debate about reproductive tissue engineering. Derivation of gametes from stem cells holds promising applications both for research and for clinical use in assisted reproduction. We explore the ethical issues connected to gametes derived from embryonic stem cells (both patient specific and non-patient specific) as well as those related to gametes derived from induced pluripotent stem cells. The technology of SCD-gametes raises moral concerns of how reproductive autonomy relates to issues of embryo destruction, safety, access, and applications beyond clinical infertility.

How We Become Who We Are: Ashley, Carla, and the Rest of Us.

PubMed

Nelson, Jamie Lindemann

2017-01-01

Lisa Freitag and Joan Liaschenko's thoughtful and important article goes directly to the under-examined heart of Ashley's case, namely to what sustains her in a habitable and intelligible identity. Though quite sympathetic with their conclusion and line of argument, I try to trouble their proceedings a bit, largely by wondering how having a specific such identity, out of several that may be in-principle available, matters to someone with Ashley's cognitive scope. I do this not simply to be contrary, but because their article also seems to me to raise issues in the ethics of bioethics-in particular, what I call the dilemma of ethical endeavor: How ought one publicly pursue deeply important and complex issues, the very raising of which may offend interlocutors who indeed have grounds for resentment. Making a habit of second guessing oneself may be part of the answer. Copyright 2017 The Journal of Clinical Ethics. All rights reserved.

Enemy Combatant Detainees: Habeas Corpus Challenges in Federal Court

DTIC Science & Technology

2007-04-06

33 Separation of Powers Issues . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 Eliminating...specifically intended to grant the authority of the President to adjudicate or remedy treaty violations could violate the doctrine of separation of powers , as...has wavered between two approaches to cases raising separation - of - powers claims, using a strict approach in some cases and a less rigid balancing

Cross-Cultural Career Psychology: Comment on Fouad, Harmon, and Borgen (1997) and Tracey, Watanabe, and Schneider (1997).

ERIC Educational Resources Information Center

Leong, Frederick T. L.

1997-01-01

Uses the theoretical framework of cultural validity and cultural specificity in career psychology to comment on theoretical and methodological issues raised by two articles on cross-cultural career psychology. Discusses the distinction between etic and emic approaches to cross-cultural research and the role of cultural context in understanding…

Whose Job Is It? Parents' Concerns About the Needs of Their Children with Language Problems

ERIC Educational Resources Information Center

Lindsay, G.; Dockrell, J.E.

2004-01-01

This study examined the perspectives of parents of children with specific speech and language difficulties in the United Kingdom and described the issues they raised when considering provision to meet their children's needs. The study used a mixed-methods approach. Data from interviews were analyzed using a computer-based qualitative interview…

The Role of Individualism/Collectivism in Critical Classroom Encounters: A Four Country Study

ERIC Educational Resources Information Center

Frankel, Robert; Swanson, Scott R.; Sagan, Mariusz

2005-01-01

Internationalization raises the issue of whether, and to what extent, the inherent culture of a country may have particular influence on the nature of service interactions, and on education (i.e., student-professor interactions) specifically. Thus the service encounter in the classroom becomes a subject of increasing importance and interest with…

The State, Parenting, and the Populist Energies of Anxiety

ERIC Educational Resources Information Center

Conroy, James C.

2010-01-01

In this essay James Conroy raises the question of how far the state should engage in the rearing of children, looking in particular at homeschooling as a site for contestation. He considers this question by looking specifically at recent developments in the United Kingdom around the elision of child safeguarding issues with concern about the…

75 FR 34769 - The University of Wisconsin; Facility Operating License No. R-74; Notice of Acceptance for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-18

... specific statement of the issue of law or fact to be raised or controverted. In addition, the petitioner... alleged facts or expert opinion which support the contention and on which the petitioner intends to rely... to establish those facts or expert opinion. The petition must include sufficient information to show...

Serving Homeless Children and Youth in Charter Schools. McKinney-Vento Law into Practice Brief Series

ERIC Educational Resources Information Center

National Center for Homeless Education at SERVE, 2013

2013-01-01

This brief summarizes McKinney-Vento Act mandates for local educational agencies (LEAs) and schools. It includes additional explanation on two issues about which charter schools have frequently raised questions: transportation, specifically to and from the school of origin, and enrollment policies, which may create barriers for homeless students.…

The generativist-interactionist debate over specific language impairment: psycholinguistics at a crossroads.

PubMed

Shanker, Stuart

2002-01-01

Certain defining problems in psychology force us to clarify both the origins and the limits of a paradigm that has long governed our thinking in a particular area of research. The current debate over the nature and causes of specific language impairment is proving to be just such an issue. In particular, the existence of the KE family, 15 of whose 37 members suffer from specific language impairment, has raised far-reaching questions about the conceptual foundations of our current views about language deficits and, indeed, about language development in general.

Chapter 13: Assessing Persistence and Other Evaluation Issues Cross-Cutting Protocol. The Uniform Methods Project: Methods for Determining Energy Efficiency Savings for Specific Measures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kurnik, Charles W; Violette, Daniel M.

Addressing other evaluation issues that have been raised in the context of energy efficiency programs, this chapter focuses on methods used to address the persistence of energy savings, which is an important input to the benefit/cost analysis of energy efficiency programs and portfolios. In addition to discussing 'persistence' (which refers to the stream of benefits over time from an energy efficiency measure or program), this chapter provides a summary treatment of these issues -Synergies across programs -Rebound -Dual baselines -Errors in variables (the measurement and/or accuracy of input variables to the evaluation).

Bioethics for clinicians: 26. Assisted reproductive technologies

PubMed Central

Shanner, Laura; Nisker, Jeffrey

2001-01-01

ASSISTED REPRODUCTIVE TECHNOLOGIES (ARTs) can be very helpful for certain patients, but ethical concerns have been raised about the inherent nature of specific techniques and the contexts in which many techniques are used. Physicians play important roles in supporting those who wish to become parents and in educating patients about impediments to fertilization and ways to promote conception. We discuss various ethical issues surrounding ARTs, including family relationships, informed choice, gender issues, embryo status and the commercialization of reproduction, as well as legal and policy issues. We examine the empirical evidence of the effectiveness of ARTs and suggest ways to approach ARTs in practice. PMID:11402801

Indexes of severity: conceptual development.

PubMed Central

Krischer, J P

1979-01-01

A discussion of severity index development is presented in relation to conceptual issues in index definition, analytic issues in index formulation and validation issues in index application. The CHOP index is discussed along with six severity indexes described in an earlier paper dealing with underlying concepts to illustrate the material presented. Replies are provided to specific questions raised in an accompanying paper discussing the Injury Severity Score. This conceptual material is presented to provide a foundation for severity index development, to suggest criteria to be used in their formulation and testing, and to identify analyses that can lead to the successful selection and application of an index for a defined purpose. PMID:468553

Curriculum translation and environmental education: considering issues of discursive intentionality, interpretation, and validity

NASA Astrophysics Data System (ADS)

Oliveira, Alandeom W.; Colak, Huseyin; Akerson, Valarie L.

2009-03-01

We would like to thank our commentators Reis, Ercikan and Alper for their insightful comments on our research study and respond in brief to a few of their criticisms. More specifically, we would like to address what we consider to be the three main issues they raise with regard to the practices of curriculum translation and implementation across languages, namely viewing speakers' intentions as a mode of signification in discourse analysis, exploring curriculum translation through an interpretive research approach, and establishing the validity of research on curriculum translation.

49 CFR 1150.36 - Exempt construction of connecting track.

Code of Federal Regulations, 2010 CFR

2010-10-01

... environmental issues have been raised or discovered during the environmental review process, the Board shall... significant environmental issues have been raised or discovered, the Board, through the Director of the Office... environmental issues cannot be made prior to the date that the exemption authority would otherwise become...

Alternative work schedules for female pharmacists.

PubMed

Mason, N A; Perry, W R; Ryan, M L

1991-01-01

The impact of the increased proportion of women in pharmacy is discussed, and two leadership positions for which part-time work schedules were implemented are described. Issues associated with the increased representation of women include pharmacist shortages, loss of future leaders, decreased staff productivity related to inadequate day-care services, and a reduced earning potential of pharmacists. Many of these problems can be addressed by altering benefit packages and work schedules to enable employees to raise children while continuing to work. Specific strategies include legislation, day-care programs, flex time and flex scheduling, telecommuting, and the creation of alternative work schedules or permanent part-time positions. At the University of Michigan, a part-time position that combines faculty and clinical responsibilities has been in place since 1988. At The Washington Hospital Center, one of the three assistant director of pharmacy positions is part-time. The women in both positions have met or exceeded job performance requirements while raising a family. Issues raised by the increasing number of female pharmacists must be addressed by the profession. Part-time work schedules are one strategy for enabling female pharmacists to meet both their family and career responsibilities.

Grandparents Raising Grandchildren: What Have We Learned Over the Past Decade?

PubMed

Hayslip, Bert; Fruhauf, Christine A; Dolbin-MacNab, Megan L

2017-06-28

In this manuscript, we update the literature over the last decade in addressing several new content areas that have emerged in the grandfamilies literature, along with issues that are still important to understanding grandparents raising their grandchildren today. The social science and gerontological literature since 2004 was accessed, reviewed, organized topically, and integrated, based upon an exhaustive PsychINFO literature search. Our review indicates an ongoing and/or growing emphasis on (a) the strengths of grandparent raising grandchildren, (b) diversity among grandfamilies along a number of parameters, (c) the social-interpersonal, cultural, and policy-related contexts of grandfamilies, (d) process-focused research, (e) parenting, parenting skills, and family relationships, (f) grandparent psychological distress, (g) targets for and the efficacy of interventions with grandfamilies, and (h) methodological issues relevant to the study of grandfamilies. We discuss the implications of our findings in terms of more completely understanding grandfamilies along a number of parameters, as well as presenting specific recommendations for future research and practice. © The Author 2017. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Ethical reflections on pharmacogenetics and DNA banking in a cohort of HIV-infected patients

PubMed Central

de Montgolfier, Sandrine; Moutel, Grégoire; Duchange, Nathalie; Theodorou, Ioannis; Hervé, Christian; Leport, Catherine

2002-01-01

The aim of this study was to analyze ethical questions concerning the storage of human biological samples to be used in genetic analyses and pharmacogenetic research based on a French experience of DNA banking in a cohort of HIV-infected patients receiving protease inhibitor treatment (APROCO). We describe the ethical issues raised during the establishment of a DNA bank, including questions dealing with autonomy, benefit to the patient, information sharing and confidentiality as well as guarantees concerning the storage and use of DNA. We describe the practical applications of themes illustrated theoretically in the literature. Most of the points raised are not specific to HIV, but some of them may be more accurate due to the characteristics of the HIV population. The questions raised are not exhaustive and we conclude with specific points that remain to be defined. Our results are summarized in the memorandum and consent form presented in the appendices. This work should allow other researchers and members of evaluation committees to enrich their considerations and should stimulate discussion on this subject. PMID:12464796

The problem of resonance in technology usage

NASA Technical Reports Server (NTRS)

Sayani, H. H.; Svoboda, C. P.

1981-01-01

Various information system tools and techniques are analyzed. A case study is presented which draws together the issues raised in three distinct cases. This case study shows a typical progression from the selection of an analysis methodology, to the adoption of an automated tool for specification and documentation, and the difficulty of fitting these into an existing life cycle development methodology.

75 FR 36705 - Regents of the University of California; Notice of Acceptance for Docketing and Opportunity for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-28

... of a specific statement of the issue of law or fact to be raised or controverted. In addition, the... statement of the alleged facts or expert opinion which support the contention and on which the petitioner... intends to rely to establish those facts or expert opinion. The petition must include sufficient...

Toward Increasing Professionalism in Public Relations: An Activity-Specific System for Categorizing Practitioners.

ERIC Educational Resources Information Center

Brownell, Mark A.; Niebauer, Walter E., Jr.

To develop a method of categorizing public relations practitioners according to a hierarchy of professionalism which would also identify what training is needed to raise those in lower levels to higher levels, a study surveyed 93 Iowa practitioners listed in the 1986-87 Public Relations Society of America Register Issue. Response rate was 66% and…

Curriculum and Psychology--Reflections on the Issues Raised at the 1983 British Psychological Society Education Section Conference.

ERIC Educational Resources Information Center

Barratt, Gill

1984-01-01

Issues concerning psychology and education that were raised at the 1983 British Psychology Society Education Section Conference are discussed. With respect to teacher training courses, a major issue is whether only practical experience and reflection on the experience can make theoretical learning relevant and usable. (RM)

Mapping Queer Bioethics: Space, Place, and Locality.

PubMed

Wahlert, Lance

2016-01-01

This article, which introduces the special issue of the Journal of Homosexuality on "Mapping Queer Bioethics," begins by offering an overview of the analytical scope of the issue. Specifically, the first half of this essay raises critical questions central to the concept of a space-related queer bioethics, such as: How do we appreciate and understand the special needs of queer parties given the constraints of location, space, and geography? The second half of this article describes each feature article in the issue, as well as the subsequent special sections on the ethics of reading literal, health-related maps ("Cartographies") and scrutinizing the history of this journal as concerns LGBT health ("Mapping the Journal of Homosexuality").

Introduction to the Special Issue: Precarious Solidarity-Preferential Access in Canadian Health Care.

PubMed

Reid, Lynette

2017-06-01

Systems of universal health coverage may aspire to provide care based on need and not ability to pay; the complexities of this aspiration (conceptual, practical, and ethical) call for normative analysis. This special issue arises in the wake of a judicial inquiry into preferential access in the Canadian province of Alberta, the Vertes Commission. I describe this inquiry and set out a taxonomy of forms of differential and preferential access. Papers in this special issue focus on the conceptual specification of health system boundaries (the concept of medical need) and on the normative questions raised by complex models of funding and delivery of care, where patients, providers, and services cross system boundaries.

Federal Tax Issues Raised by International Study Abroad Programs.

ERIC Educational Resources Information Center

Harding, Bertrand M., Jr.

2000-01-01

Identifies and describes tax issues raised by study abroad programs and suggests steps that a college or university can take to minimize or eliminate adverse U.S. and foreign tax exposure to both itself and its employees. (EV)

Feedback about Teaching in Higher Ed: Neglected Opportunities to Promote Change

PubMed Central

Evans, Mara; Brickman, Peggy

2014-01-01

Despite ongoing dissemination of evidence-based teaching strategies, science teaching at the university level is less than reformed. Most college biology instructors could benefit from more sustained support in implementing these strategies. One-time workshops raise awareness of evidence-based practices, but faculty members are more likely to make significant changes in their teaching practices when supported by coaching and feedback. Currently, most instructional feedback occurs via student evaluations, which typically lack specific feedback for improvement and focus on teacher-centered practices, or via drop-in classroom observations and peer evaluation by other instructors, which raise issues for promotion, tenure, and evaluation. The goals of this essay are to summarize the best practices for providing instructional feedback, recommend specific strategies for providing feedback, and suggest areas for further research. Missed opportunities for feedback in teaching are highlighted, and the sharing of instructional expertise is encouraged. PMID:26086652

Ethics review as a component of institutional approval for a multicentre continuous quality improvement project: the investigator's perspective.

PubMed

Ezzat, Hanna; Ross, Sue; von Dadelszen, Peter; Morris, Tara; Liston, Robert; Magee, Laura A

2010-07-30

For ethical approval of a multicentre study in Canada, investigators must apply separately to individual Research Ethics Boards (REBs). In principle, the protection of human research subjects is of utmost importance. However, in practice, the process of multicentre ethics review can be time consuming and costly, requiring duplication of effort for researchers and REBs. We used our experience with ethical review of The Canadian Perinatal Network (CPN), to gain insight into the Canadian system. The applications forms of 16 different REBs were abstracted for a list of standardized items. The application process across sites was compared. Correspondence between the REB and the investigators was documented in order to construct a timeline to approval, identify the specific issues raised by each board, and describe how they were resolved. Each REB had a different application form. Most (n = 9) had a two or three step application process. Overall, it took a median of 31 days (range 2-174 days) to receive an initial response from the REB. Approval took a median of 42 days (range 4-443 days). Privacy and consent were the two major issues raised. Several additional minor or administrative issues were raised which delayed approval. For CPN, the Canadian REB process of ethical review proved challenging. REBs acted independently and without unified application forms or submission procedures. We call for a critical examination of the ethical, privacy and institutional review processes in Canada, to determine the best way to undertake multicentre review.

Ethical issues in the development and implementation of nutrition-related public health policies and interventions: A scoping review.

PubMed

Hurlimann, Thierry; Peña-Rosas, Juan Pablo; Saxena, Abha; Zamora, Gerardo; Godard, Béatrice

2017-01-01

The limited integration of ethics in nutrition-related public health policies and interventions is one major concern for those who have the task of implementing them. Ethical challenges that are overlooked during the development of such interventions could raise serious ethical issues during their implementation and even after. As a result, these decision makers need technical support and ethical guidance for adaptation of interventions to local (cultural, social, economic, etc.) contexts. The goal of this scoping review is to delineate and "map" the range of ethical issues in nutrition-related public health interventions, as well as the range of the various fields in which they may arise. A scoping review of empirical research and conceptual literature was conducted following the framework of Arksey and O'Malley. Searches using PubMed with Medical Subject Headings (MeSH) categories and Advanced Search Builder as well as in the Global Health Library were performed. The final sample consists of 169 publications. The ethics of public health prevention or treatment of obesity and non-communicable diseases is the most explicitly and frequently discussed subject. In comparison, ethical issues raised by public health interventions in the fields of undernutrition, breastfeeding, vitamin/mineral supplementation and food fortification, food security, food sustainability and food safety are addressed in a lower proportion of the sample. The results illustrate the various natures, types, and scopes of existing public health nutrition-related interventions, and the various ethical issues that may be raised by these interventions, in addition to the numerous and different contexts in which they may be implemented. The ethical issues faced in the development and implementation of nutrition-related public health interventions are varied and cannot be equated with, nor generalized about, when dealing with specific activities in this field. More importantly, these ethical issues cannot be managed without a careful consideration for the complexity of contexts in which nutrition-related interventions are expected to be implemented. These interventions engage a variety of actors with diverse perspectives and interests. We discuss these challenges and also comment on the importance of considering ethical impacts in the monitoring and evaluation of such interventions. General ethical frameworks or recommendations-although useful-cannot be expected to provide policy makers, implementators and other public health personnel with sufficient practical ethical guidance as they cannot consider and anticipate the particularities of all specific nutrition-related public health interventions and the complexity of the contexts in which they are implemented. Further research is needed in order to develop more targeted ethical frameworks.

Stem cells to gametes: how far should we go?

PubMed

Whittaker, Peter

2007-03-01

Murine embryonic stem cells have recently been shown to be capable of differentiating in vitro into oocytes or sperm. Should these findings be duplicated using human embryonic stem cells, this would raise a number of social and ethical concerns, some specific to these particular developments, others shared with other aspects of stem cell research. This review outlines the properties of stem cells and their conversion to gametes. Concerns raised include embryo destruction, quality of gametes derived in this way, possibility for children with two male biological parents, movement towards germ line gene therapy and 'designer babies', and the future impacts on health service provisions. It is important that public discussion of some of these issues should take place.

The full spectrum of ethical issues in dementia care: systematic qualitative review.

PubMed

Strech, Daniel; Mertz, Marcel; Knüppel, Hannes; Neitzke, Gerald; Schmidhuber, Martina

2013-06-01

Integrating ethical issues in dementia-specific training material, clinical guidelines and national strategy plans requires an unbiased awareness of all the relevant ethical issues. To determine systematically and transparently the full spectrum of ethical issues in clinical dementia care. We conducted a systematic review in Medline (restricted to English and German literature published between 2000 and 2011) and Google books (with no restrictions). We applied qualitative text analysis and normative analysis to categorise the spectrum of ethical issues in clinical dementia care. The literature review retrieved 92 references that together mentioned a spectrum of 56 ethical issues in clinical dementia care. The spectrum was structured into seven major categories that consist of first- and second-order categories for ethical issues. The systematically derived spectrum of ethical issues in clinical dementia care presented in this paper can be used as training material for healthcare professionals, students and the public for raising awareness and understanding of the complexity of ethical issues in dementia care. It can also be used to identify ethical issues that should be addressed in dementia-specific training programmes, national strategy plans and clinical practice guidelines. Further research should evaluate whether this new genre of systematic reviews can be applied to the identification of ethical issues in other cognitive and somatic diseases. Also, the practical challenges in addressing ethical issues in training material, guidelines and policies need to be evaluated.

77 FR 58406 - Certain LED Photographic Lighting Devices and Components Thereof; Notice of Request for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-20

...Notice is hereby given that the presiding administrative law judge (``ALJ'') has issued a Final Initial Determination and Recommended Determination on Remedy and Bonding in the above-captioned investigation. The Commission is soliciting comments on public interest issues raised by the recommended relief, specifically a general exclusion order against certain LED photographic lighting devices and components thereof. The ALJ alternatively recommended a limited exclusion order against certain LED photographic lighting devices and components thereof manufactured or sold by the respondents found in violation of 19 U.S.C. 1337.

Influence Map Methodology for Evaluating Systemic Safety Issues

NASA Technical Reports Server (NTRS)

2008-01-01

"Raising the bar" in safety performance is a critical challenge for many organizations, including Kennedy Space Center. Contributing-factor taxonomies organize information about the reasons accidents occur and therefore are essential elements of accident investigations and safety reporting systems. Organizations must balance efforts to identify causes of specific accidents with efforts to evaluate systemic safety issues in order to become more proactive about improving safety. This project successfully addressed the following two problems: (1) methods and metrics to support the design of effective taxonomies are limited and (2) influence relationships among contributing factors are not explicitly modeled within a taxonomy.

Supplemental Notice to the Proposed NPDES Electronic Reporting Rule Fact Sheet

EPA Pesticide Factsheets

This notice allows EPA to identify the issues raised by commenters during the public comment period, clarify any misunderstandings about the proposal, and discuss possibilities for how EPA might modify the rule to address issues raised by stakeholders.

Has ICT come of age? Recurring debates on the role of ICT in education, 1982 2004

NASA Astrophysics Data System (ADS)

Wellington, Jerry

2005-01-01

Information and Communication Technology (ICT) has now been used in science and technology education, and in other areas of the curriculum, for over 20 years. ICT has been introduced into school education through a series of heavily funded government initiatives since the launch of microcomputers into schools in 1981. This spate of initiatives has involved a mixture of hardware, software and teacher-training, though not always in a coordinated fashion. A number of issues raised by the advent of ICT have specific relevance to those involved in science and technology education at all levels, but equally, the issues and debates highlighted in this paper are of a generic nature and are applicable to ICT use across the curriculum. I argue that the debates raised by ICT use fall into three categories: the vocational, the pedagogical and the societal. These debates are likely to be perennial and recurring, whatever the advancement made in the technology itself.

Mapping of human genome raises serious issues for individual vs. corporate rights.

PubMed

Court, J

2001-01-01

Unrestricted corporate control of genetic technologies opens a pandora's box for the balance of power between individuals and corporations. This column provides an overview of the issues raised by commercialization of the human genome from a citizen advocate's perspective.

Bond Issues.

ERIC Educational Resources Information Center

Pollack, Rachel H.

2000-01-01

Notes trends toward increased borrowing by colleges and universities and offers guidelines for institutions that are considering issuing bonds to raise money for capital projects. Discussion covers advantages of using bond financing, how use of bonds impacts on traditional fund raising, other cautions and concerns, and some troubling aspects of…

Draft Environmental Impact Report/Environmental Impact Statement. Cullinan Ranch Specific Plan.

DTIC Science & Technology

1983-05-01

COMMITMENTS OF RESOURCES WHICH WOULD BE INVOLVED IN THE PROPOSED ACTION SHOULD IT BE IMPLEMENTED 150 VII. GROWTH -INDUCING IMPACTS OF THE PROPOSED ACTION 151... conditions Involving soft bay mud and peat deposits, and 3) raise the surface level of the project to accnmmodate planned settlement and provide...data becomes available. These issues are indicated with an asterisk (*). 1. Growth inducement with required expansion of Infrastructure to support

Ethical Issues in mHealth Research Involving Persons Living with HIV/AIDS and Substance Abuse

PubMed Central

Labrique, Alain B.; Kirk, Gregory D.; Westergaard, Ryan P.; Merritt, Maria W.

2013-01-01

We aim to raise awareness and stimulate dialogue among investigators and research ethics committees regarding ethical issues that arise specifically in the design and conduct of mHealth research involving persons living with HIV/AIDS and substance abuse. Following a brief background discussion of mHealth research in general, we offer a case example to illustrate the characteristics of mHealth research involving people living with HIV/AIDS and substance abuse. With reference to a well-established systematic general ethical framework for biomedical research with human participants, we identify a range of ethical issues that have particular salience for the protection of participants in mHealth research on HIV/AIDS and substance abuse. PMID:24171110

14 CFR 302.705 - Further procedures.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL... designated time, or if a timely filed answer raises no material issue of fact, the DOT decisionmaker may... answer raising a material issue of fact is filed within the time designated in the Department's order...

14 CFR 302.705 - Further procedures.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL... designated time, or if a timely filed answer raises no material issue of fact, the DOT decisionmaker may... answer raising a material issue of fact is filed within the time designated in the Department's order...

14 CFR 302.705 - Further procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL... designated time, or if a timely filed answer raises no material issue of fact, the DOT decisionmaker may... answer raising a material issue of fact is filed within the time designated in the Department's order...

14 CFR 302.705 - Further procedures.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL... designated time, or if a timely filed answer raises no material issue of fact, the DOT decisionmaker may... answer raising a material issue of fact is filed within the time designated in the Department's order...

14 CFR 302.705 - Further procedures.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) PROCEDURAL... designated time, or if a timely filed answer raises no material issue of fact, the DOT decisionmaker may... answer raising a material issue of fact is filed within the time designated in the Department's order...

Can the EVIDEM Framework Tackle Issues Raised by Evaluating Treatments for Rare Diseases: Analysis of Issues and Policies, and Context-Specific Adaptation.

PubMed

Wagner, Monika; Khoury, Hanane; Willet, Jacob; Rindress, Donna; Goetghebeur, Mireille

2016-03-01

The multiplicity of issues, including uncertainty and ethical dilemmas, and policies involved in appraising interventions for rare diseases suggests that multicriteria decision analysis (MCDA) based on a holistic definition of value is uniquely suited for this purpose. The objective of this study was to analyze and further develop a comprehensive MCDA framework (EVIDEM) to address rare disease issues and policies, while maintaining its applicability across disease areas. Specific issues and policies for rare diseases were identified through literature review. Ethical and methodological foundations of the EVIDEM framework v3.0 were systematically analyzed from the perspective of these issues, and policies and modifications of the framework were performed accordingly to ensure their integration. Analysis showed that the framework integrates ethical dilemmas and issues inherent to appraising interventions for rare diseases but required further integration of specific aspects. Modification thus included the addition of subcriteria to further differentiate disease severity, disease-specific treatment outcomes, and economic consequences of interventions for rare diseases. Scoring scales were further developed to include negative scales for all comparative criteria. A methodology was established to incorporate context-specific population priorities and policies, such as those for rare diseases, into the quantitative part of the framework. This design allows making more explicit trade-offs between competing ethical positions of fairness (prioritization of those who are worst off), the goal of benefiting as many people as possible, the imperative to help, and wise use of knowledge and resources. It also allows addressing variability in institutional policies regarding prioritization of specific disease areas, in addition to existing uncertainty analysis available from EVIDEM. The adapted framework measures value in its widest sense, while being responsive to rare disease issues and policies. It provides an operationalizable platform to integrate values, competing ethical dilemmas, and uncertainty in appraising healthcare interventions.

Exporting DBCP and other banned pesticides: consideration of ethical issues.

PubMed

Lowry, L K; Frank, A L

1999-01-01

Many developed countries permit the export of pesticides that are banned, restricted, or unregistered within their own borders. This practice, which leads to the exposure of agricultural workers in developing countries to high levels of pesticides that are not permitted in the country of manufacture, raises many ethical issues as well as economic, social, political, and public health issues. Worldwide attempts to control export of such pesticides, through the FAO/UNEP Prior Informed Consent program, moves this issue in the right direction. This article explores the current U.S. and international practices, using the specific example of export of DBCP to banana-producing countries. The actions taken by multinational corporations, manufacturers of the pesticides, and public health officials in both the exporting and importing countries are explored, along with the impacts on workers, local economies, governments, and the environment.

Educators' Degrees Earned on Internet Raise Fraud Issues

ERIC Educational Resources Information Center

Trotter, Andrew

2004-01-01

This article discusses how the degrees earned by a dozen educators on the Internet have raised fraud issues. Small firms known as "credential evaluators" help states and school districts detect educators who present phony or flimsy academic credentials from overseas institutions--a safeguard that is becoming more important with the…

Controversial Issues in Our Schools. Fastback 146.

ERIC Educational Resources Information Center

Goldstein, William

There is virtually nothing taught in the American public school that is not potentially explosive at some time or place. America's cultural makeup provides for the development of controversy whenever such issues as sex, religion, politics, and economics are raised, and particularly when they are raised in the school environment. School…

Advancing rights for women: the role of litigation.

PubMed

Cabal, Luisa

2006-12-01

Litigation is becoming an increasingly attractive advocacy tool for human rights movements around the world. It has served as an effective strategy not only for reforming or enforcing laws that deny or protect basic human rights, but also for raising awareness of and mobilizing support for human rights issues. In this article, which is based on a presentation at a symposium session at the conference, Luisa Cabal focuses on a specific area within the realm of women's health and rights--the rights of HIV-positive women and girls, and in particular, violations they experience vis-à-vis access to health care--and discusses the potential for litigation to help raise awareness and advance efforts to protect and promote human rights in this area.

Ethics review as a component of institutional approval for a multicentre continuous quality improvement project: the investigator's perspective

PubMed Central

2010-01-01

Background For ethical approval of a multicentre study in Canada, investigators must apply separately to individual Research Ethics Boards (REBs). In principle, the protection of human research subjects is of utmost importance. However, in practice, the process of multicentre ethics review can be time consuming and costly, requiring duplication of effort for researchers and REBs. We used our experience with ethical review of The Canadian Perinatal Network (CPN), to gain insight into the Canadian system. Methods The applications forms of 16 different REBs were abstracted for a list of standardized items. The application process across sites was compared. Correspondence between the REB and the investigators was documented in order to construct a timeline to approval, identify the specific issues raised by each board, and describe how they were resolved. Results Each REB had a different application form. Most (n = 9) had a two or three step application process. Overall, it took a median of 31 days (range 2-174 days) to receive an initial response from the REB. Approval took a median of 42 days (range 4-443 days). Privacy and consent were the two major issues raised. Several additional minor or administrative issues were raised which delayed approval. Conclusions For CPN, the Canadian REB process of ethical review proved challenging. REBs acted independently and without unified application forms or submission procedures. We call for a critical examination of the ethical, privacy and institutional review processes in Canada, to determine the best way to undertake multicentre review. PMID:20673343

Flood, disaster, and turmoil: social issues in cleft and craniofacial care and crisis relief.

PubMed

Strauss, Ronald P; van Aalst, John A; Fox, Lynn; Stein, Margot; Moses, Michael; Cassell, Cynthia H

2011-11-01

To examine social issues in the conduct of cleft and craniofacial care through relief programs in disrupted crisis contexts. Social, health policy, and ethical analyses. At best, craniofacial team care is multidisciplinary, coordinated, and sustained, requiring a long-term relationship between team members, patients, and families. Disasters and societal turmoil interrupt such relationships, causing craniofacial care to become a secondary concern. Providing craniofacial team care in a crisis setting requires rebuilding disrupted coordination and communication. Crisis relief care involves a complex set of expectations and responsibilities and raises issues such as (1) quality assurance, infection control, appropriate standards of care, and follow-up care/continuity; (2) equity of access to services and clinical ethics in the context of war and/or deprivation; (3) training of visitors in the local nation or site; (4) disciplinary composition of teams, interprofessional communication/rivalry, and credentials of clinicians; (5) ownership of the site and local visitor relations; (6) fundraising and marketing strategies; and (7) ethical issues in the doctor-patient relationship. Specific ethical standards for international cleft and craniofacial care delivery also apply to domestic and global crisis relief contexts. Guidance on issues related to professional experience, informed consent, and continuity of care will help care providers address social and ethical issues raised in crisis relief programs. This paper proposes that the Position Paper of the American Cleft Palate-Craniofacial Association (ACPA) on International Treatment Programs should be used as a template to develop and disseminate a set of standards that apply to crisis relief.

Ethics guidelines, health research and Indigenous Australians.

PubMed

Anderson, Ian; Griew, Robert; McAullay, Daniel

2003-02-01

In this paper we overview the findings of a literature review that was undertaken to guide the revision of the Guidelines on Ethical Matters in Aboriginal and Torres Strait Islander Health Research (NH&MRC, 1991). The literature reviewed, in general, supported the development of specific research guidelines for Aboriginal and Torres Strait Islander contexts. The findings of this review were analysed thematically, and a number of key issues were identified for consideration in the review process. We present a summary of these key issues. In the final section of the paper we consider in more detail two of the key issues raised in the review process (the assessment of relevance or benefit of proposed research; and the process of consultation and negotiation of collective consent) in order to critically consider how these issue should be engaged in revised guidelines. On the basis of this analysis, it is our contention that specific guidelines on key issues are limited to the extent to which they can anticipate all possible research contexts. In order to address this problem, and guide researchers, guidelines should also explicitly outline the values, from an Aboriginal and Torres Islander perspective that are foundational to an ethical research process.

75 FR 78944 - Proposed Establishment of the Pine Mountain-Mayacmas Viticultural Area; Comment Period Reopening

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-17

...The Alcohol and Tobacco Tax and Trade Bureau is reopening the comment period for Notice No. 105, which concerned a proposal to establish an American viticultural area having the name Pine Mountain- Mayacamas. This reopening of the comment period solicits comments from the public on issues that were raised in public comments received in response to Notice No. 105. Three specific issues which we seek comments on concern the proper name for the proposed viticultural area, the viticultural significance of a suggested alternative name for the viticultural area, and the propriety of expanding the boundary of the proposed viticultural area.

Ethics, engineers and drama.

PubMed

Monk, John

2009-03-01

This paper describes four plays which illustrate ethical themes relevant to engineers and which could be used as a resource for engineers who wish to explore ethical topics and their relationship with professional practice. The plays themselves have been chosen because a character in the play is involved in engineering activities. Each play is analysed to highlight some of the ethical issues the play raises. Often ethical topics are presented in abstract terms but the plays relate ethical issues to individuals and individual actions in specific situations that connect either directly or figuratively to practical situations engineers find themselves in. The paper describes how the resources have or could be used in an educational programme.

A Reply to Diem et al.'s Commentary on a Recent Literature Contribution Focused on Urban-Induced Rainfall in Atlanta

NASA Technical Reports Server (NTRS)

Shepherd, J. Marshall

2004-01-01

A response is provided to Diem and colleagues discussion on the whether urbanization-enhanced precipitation should be maximized in the South-Southeast of Atlanta, Georgia as documented in Shepherd et al. (2003). Diem and colleagues have offered a critical response to Shepherd et al. (2002). The response herein offers both general and specific responses to issues raised by Diem and colleagues.

49 CFR 1105.12 - Sample newspaper notices for abandonment exemption cases.

Code of Federal Regulations, 2010 CFR

2010-10-01

... original and 10 copies of any pleading that raises matters other than environmental issues (such as trails... and 10 copies of any pleading that raises matters other than environmental issues (such as trails use... OF ENVIRONMENTAL LAWS § 1105.12 Sample newspaper notices for abandonment exemption cases. In every...

40 CFR 78.5 - Limitation on filing or presenting new evidence and raising new issues.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Limitation on filing or presenting new evidence and raising new issues. 78.5 Section 78.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPEAL PROCEDURES § 78.5 Limitation on filing or presenting...

Issues Raised by the Follow Through Evaluation.

ERIC Educational Resources Information Center

House, Ernest R.; Hutchins, Elizabeth J.

This paper presents a discussion of issues raised in the evaluation of Project Follow Through reported by Abt Associates. The paper suggests that many of the problems inherent in the design of both the program and the evaluation stem from the underlying assumption that one educational model could be found which would best alleviate the educational…

Dilemmas in Medicine, 2nd Edition 1977. CEM Probe.

ERIC Educational Resources Information Center

Undy, Harry, Ed.

Published for secondary school youth in England, the PROBE series presents provocative information and discussion questions on topical themes. The focus of this issue is on aspects of medicine which raise moral dilemmas for doctors, patients, and society in general. This issue contains case studies which illustrate ethical questions raised by the…

48 CFR 6101.21 - Hearing procedures [Rule 21].

Code of Federal Regulations, 2010 CFR

2010-10-01

...) Nature and conduct of hearings. (1) Except when necessary to maintain the confidentiality of protected... subpoena pursuant to 6101.16(h) (Rule 16(h)). (h) Issues not raised by pleadings. If evidence is objected to at a hearing on the ground that it is not within the issues raised by the pleadings, it may...

Ethical issues in the development and implementation of nutrition-related public health policies and interventions: A scoping review

PubMed Central

Peña-Rosas, Juan Pablo; Saxena, Abha; Zamora, Gerardo

2017-01-01

Background The limited integration of ethics in nutrition-related public health policies and interventions is one major concern for those who have the task of implementing them. Ethical challenges that are overlooked during the development of such interventions could raise serious ethical issues during their implementation and even after. As a result, these decision makers need technical support and ethical guidance for adaptation of interventions to local (cultural, social, economic, etc.) contexts. Aim The goal of this scoping review is to delineate and “map” the range of ethical issues in nutrition-related public health interventions, as well as the range of the various fields in which they may arise. Methods A scoping review of empirical research and conceptual literature was conducted following the framework of Arksey and O’Malley. Searches using PubMed with Medical Subject Headings (MeSH) categories and Advanced Search Builder as well as in the Global Health Library were performed. The final sample consists of 169 publications. Results The ethics of public health prevention or treatment of obesity and non-communicable diseases is the most explicitly and frequently discussed subject. In comparison, ethical issues raised by public health interventions in the fields of undernutrition, breastfeeding, vitamin/mineral supplementation and food fortification, food security, food sustainability and food safety are addressed in a lower proportion of the sample. The results illustrate the various natures, types, and scopes of existing public health nutrition-related interventions, and the various ethical issues that may be raised by these interventions, in addition to the numerous and different contexts in which they may be implemented. Discussion The ethical issues faced in the development and implementation of nutrition-related public health interventions are varied and cannot be equated with, nor generalized about, when dealing with specific activities in this field. More importantly, these ethical issues cannot be managed without a careful consideration for the complexity of contexts in which nutrition-related interventions are expected to be implemented. These interventions engage a variety of actors with diverse perspectives and interests. We discuss these challenges and also comment on the importance of considering ethical impacts in the monitoring and evaluation of such interventions. Conclusion General ethical frameworks or recommendations–although useful–cannot be expected to provide policy makers, implementators and other public health personnel with sufficient practical ethical guidance as they cannot consider and anticipate the particularities of all specific nutrition-related public health interventions and the complexity of the contexts in which they are implemented. Further research is needed in order to develop more targeted ethical frameworks. PMID:29073186

Hazard and risk assessment of industrial chemicals in the occupational context in Europe: some current issues.

PubMed

Fairhurst, S

2003-11-01

This paper is about industrial chemicals, the manner in which their toxicity is assessed and the use of such assessments in regulatory decision-making. It begins with general points concerning toxicological data availability and hazard identification, then moves on to risk assessment and occupational exposure limits, and finally looks briefly at three specific toxicological issues, asthma, chronic toxic encephalopathy, and "low toxicity" dust effects on the lung, where the science is far from resolved. The overall purpose of the paper is to raise, or perhaps to act as a reminder of a number of issues of particular relevance to industrial chemicals and the occupational setting, and hopefully to prompt further thinking and perhaps some new initiatives directed at the areas in question.

Anorexia nervosa in a girl of Chinese origin: psychological, somatic and transcultural factors.

PubMed

Demarque, Mélissa; Guzman, Gabriela; Morrison, Elodie; Ahovi, Jonathan; Moro, Marie Rose; Blanchet-Collet, Corinne

2015-04-01

The increased prevalence of anorexia nervosa reported in non-Western societies inevitably raises the issue of the influence of cultural factors in the genesis and the patterns of this disorder. Anorexia nervosa is not a straightforward Western culture-bound syndrome, although an influence of Western ideals of thinness does exist. The illness seems more related to rapid cultural shifts, either societal or individual, such as those occurring in the migratory process. Migrants and their children have to face the acculturation process and may experience a culture-clash. The pathology can also fulfil a positive acculturative function. This is a case study concerning a second-generation Chinese girl born in France presenting with anorexia nervosa. This case leads us to raise the issue of the choice of diagnostic criteria in relation to cultural background. We will also discuss the impact of the family's migratory history on the construction of identity in adolescence. Finally we will explore the specific features of care provision for anorexia nervosa in a transcultural setting. © The Author(s) 2013.

25 CFR 1000.193 - Who may raise the issue of limitation or reduction of services, contracts, or funding?

Code of Federal Regulations, 2011 CFR

2011-04-01

..., INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Limitation and/or Reduction of BIA Services..., or funding? BIA or any affected Tribe/Consortium or Tribal organization may raise the issue that a...

25 CFR 1000.193 - Who may raise the issue of limitation or reduction of services, contracts, or funding?

Code of Federal Regulations, 2010 CFR

2010-04-01

..., INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Limitation and/or Reduction of BIA Services..., or funding? BIA or any affected Tribe/Consortium or Tribal organization may raise the issue that a...

25 CFR 1000.193 - Who may raise the issue of limitation or reduction of services, contracts, or funding?

Code of Federal Regulations, 2013 CFR

2013-04-01

..., INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Limitation and/or Reduction of BIA Services..., or funding? BIA or any affected Tribe/Consortium or Tribal organization may raise the issue that a...

25 CFR 1000.193 - Who may raise the issue of limitation or reduction of services, contracts, or funding?

Code of Federal Regulations, 2012 CFR

2012-04-01

..., INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Limitation and/or Reduction of BIA Services..., or funding? BIA or any affected Tribe/Consortium or Tribal organization may raise the issue that a...

MDGs: Most Distracting Gimmicks?

ERIC Educational Resources Information Center

Antrobus, Peggy

2005-01-01

The MDGs provide a strategic entry point for raising issues that are important to women with people who pay no attention otherwise. In this article, the author gives her opinion about MDGs. She has three reasons for taking interest: (1) to talk about issues she wants to raise; (2) to advance women's interest and agendas; and (3) to get resources…

Babbitt's Brothers & Sisters: Raising Ethical Issues in Business Literature.

ERIC Educational Resources Information Center

Halpern, Jeanne W.

A college-level course in business literature is an ideal place to raise and discuss ethical issues. To be successful, a teacher of this course must engage student interest, help the students articulate and understand their own ethical attitudes, clarify the stance and artistry of the author, and refine student responses to ethical questions. When…

Public Libraries and Private Fund Raising: Opportunities and Issues.

ERIC Educational Resources Information Center

Jeavons, Thomas H.

In the context of faster growth of community information needs and demands than growth of public funds, questions about where new resources can be found are the subject of much discussion within the library profession. This report is an attempt to raise questions and clarify issues that should be considered in advance of the formulation of library…

Experimental investigation of orbitally shaken bioreactor hydrodynamics

NASA Astrophysics Data System (ADS)

Reclari, Martino; Dreyer, Matthieu; Farhat, Mohamed

2010-11-01

The growing interest in the use of orbitally shaken bioreactors for mammalian cells cultivation raises challenging hydrodynamic issues. Optimizations of mixing and oxygenation, as well as similarity relations between different culture scales are still lacking. In the present study, we investigated the relation between the shape of the free surface, the mixing process and the velocity fields, using specific image processing of high speed visualization and Laser Doppler velocimetry. Moreover, similarity parameters were identified for scale-up purposes.

Neuroscientists' everyday experiences of ethics: the interplay of regulatory, professional, personal and tangible ethical spheres.

PubMed

Brosnan, Caragh; Cribb, Alan; Wainwright, Steven P; Williams, Clare

2013-11-01

The ethical issues neuroscience raises are subject to increasing attention, exemplified in the emergence of the discipline neuroethics. While the moral implications of neurotechnological developments are often discussed, less is known about how ethics intersects with everyday work in neuroscience and how scientists themselves perceive the ethics of their research. Drawing on observation and interviews with members of one UK group conducting neuroscience research at both the laboratory bench and in the clinic, this article examines what ethics meant to these researchers and delineates four specific types of ethics that shaped their day-to-day work: regulatory, professional, personal and tangible. While the first three categories are similar to those identified elsewhere in sociological work on scientific and clinical ethics, the notion of 'tangible ethics' emerged by attending to everyday practice, in which these scientists' discursive distinctions between right and wrong were sometimes challenged. The findings shed light on how ethical positions produce and are, in turn, produced by scientific practice. Informing sociological understandings of neuroscience, they also throw the category of neuroscience and its ethical specificity into question, given that members of this group did not experience their work as raising issues that were distinctly neuro-ethical. © 2013 The Authors. Sociology of Health & Illness © 2013 Foundation for the Sociology of Health & Illness/John Wiley & Sons Ltd.

Exclusive contracts in the hospital setting: a two-edged sword, part 1: legal issues.

PubMed

Portman, Robert M

2007-05-01

Hospitals routinely enter into contracts with radiology groups for the right to be the exclusive provider of radiology services at the facility in exchange for the group agreeing to provide and manage all aspects of that service within the hospital. These "exclusive contracts" generally result in the radiology department and associated equipment being closed off to physicians who are not part of the contracting group. Exclusive contracts are generally considered to be good for physicians who have them and bad for those excluded by them. In fact, while exclusive contracts offer obvious benefits to the physicians who receive them and obvious disadvantages for those who are excluded, they also present pitfalls for physicians in the chosen group. Part I of this article discusses the legal issues raised by exclusive contracts. Although these agreements appear to be anti-competitive, most courts have rejected antitrust challenges to exclusive contracts. Excluded physicians have had much greater success in attacking exclusive contracting arrangements on breach of contract and procedural/due process grounds. Exclusive contracting arrangements can also raise concerns under the Medicare-Medicaid anti-kickback statute if the contracting physicians are required to pay consideration or accept less than fair market value compensation in exchange for exclusive contracts. These agreements can also raise issues under the Stark II physician self-referral law if the contracting physicians are in a position to refer Medicare or Medicaid patients to the hospital. Part II of this article will discuss the advantages and disadvantages of exclusive contracts for physicians covered and not covered by such contracts, as well as strategies for avoiding them or minimizing their potential adverse impact. It also will discuss specific provisions of exclusive contracts that should be included or avoided.

Advanced software development workstation. Comparison of two object-oriented development methodologies

NASA Technical Reports Server (NTRS)

Izygon, Michel E.

1992-01-01

This report is an attempt to clarify some of the concerns raised about the OMT method, specifically that OMT is weaker than the Booch method in a few key areas. This interim report specifically addresses the following issues: (1) is OMT object-oriented or only data-driven?; (2) can OMT be used as a front-end to implementation in C++?; (3) the inheritance concept in OMT is in contradiction with the 'pure and real' inheritance concept found in object-oriented (OO) design; (4) low support for software life-cycle issues, for project and risk management; (5) uselessness of functional modeling for the ROSE project; and (6) problems with event-driven and simulation systems. The conclusion of this report is that both Booch's method and Rumbaugh's method are good OO methods, each with strengths and weaknesses in different areas of the development process.

Deep Learning in Medical Image Analysis

PubMed Central

Shen, Dinggang; Wu, Guorong; Suk, Heung-Il

2016-01-01

The computer-assisted analysis for better interpreting images have been longstanding issues in the medical imaging field. On the image-understanding front, recent advances in machine learning, especially, in the way of deep learning, have made a big leap to help identify, classify, and quantify patterns in medical images. Specifically, exploiting hierarchical feature representations learned solely from data, instead of handcrafted features mostly designed based on domain-specific knowledge, lies at the core of the advances. In that way, deep learning is rapidly proving to be the state-of-the-art foundation, achieving enhanced performances in various medical applications. In this article, we introduce the fundamentals of deep learning methods; review their successes to image registration, anatomical/cell structures detection, tissue segmentation, computer-aided disease diagnosis or prognosis, and so on. We conclude by raising research issues and suggesting future directions for further improvements. PMID:28301734

Carrier testing for spinal muscular atrophy

PubMed Central

Gitlin, Jonathan M.; Fischbeck, Kenneth; Crawford, Thomas O.; Cwik, Valerie; Fleischman, Alan; Gonye, Karla; Heine, Deborah; Hobby, Kenneth; Kaufmann, Petra; Keiles, Steven; MacKenzie, Alex; Musci, Thomas; Prior, Thomas; Lloyd-Puryear, Michele; Sugarman, Elaine A.; Terry, Sharon F.; Urv, Tiina; Wang, Ching; Watson, Michael; Yaron, Yuval; Frosst, Phyllis; Howell, R. Rodney

2014-01-01

Spinal muscular atrophy is the most common fatal hereditary disease among newborns and infants. There is as yet no effective treatment. Although a carrier test is available, currently there is disagreement among professional medical societies who proffer standards of care as to whether or not carrier screening for spinal muscular atrophy should be offered as part of routine reproductive care. This leaves health care providers without clear guidance. In fall 2009, a meeting was held by National Institutes of Health to examine the scientific basis for spinal muscular atrophy carrier screening and to consider the issues that accompany such screening. In this article, the meeting participants summarize the discussions and conclude that pan-ethnic carrier screening for spinal muscular atrophy is technically feasible and that the specific study of implementing a spinal muscular atrophy carrier screening program raises broader issues about determining the scope and specifics of carrier screening in general. PMID:20808230

ONC201: Stressing tumors to death.

PubMed

Endo Greer, Yoshimi; Lipkowitz, Stanley

2016-02-16

The small molecule ONC201 was identified in a screen for compounds that would induce expression of the gene encoding tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in tumors and thus cause an autocrine- or paracrine-induced death in tumor cells. Two Research Articles in this issue of Science Signaling by Ishizawa et al. and Kline et al. describe how ONC201 can also trigger cytotoxicity by inducing a stress response. The mechanisms of the stress response induced differ between hematological malignancies and solid tumors, highlighting the complexity of ONC201-induced toxicity and raising intriguing issues of tissue-specific pathways activated by the drug. Copyright © 2016, American Association for the Advancement of Science.

Introduction: Reengaging with instruments.

PubMed

Taub, Liba

2011-12-01

Over the past twenty years or so, historians of science have become increasingly sensitized to issues involved in studying and interpreting scientific and medical instruments. The contributors to this Focus section are historians of science who have worked closely with museum objects and collections, specifically instruments used in scientific and medical contexts. Such close engagement by historians of science is somewhat rare, provoking distinctive questions as to how we define and understand instruments, opening up issues regarding the value of broken or incomplete objects, and raising concerns about which scientific and medical artifacts are displayed and interpreted in museums and in what manner. It is hoped that these essays point historians of science in new directions for reengaging with scientific objects and collections.

War, terrorism, and children.

PubMed

DeRanieri, Joseph T; Clements, Paul T; Clark, Kathleen; Kuhn, Douglas Wolcik; Manno, Martin S

2004-04-01

Many caregivers are encountering the issue of communicating with children and adolescents about current world events, specifically war and terrorism. As health care providers, it is important to raise awareness of how children may understand, interpret, and respond to related fears and concerns. Although honesty and reassurance are clearly the best approach, it is important to provide information that is developmentally appropriate. Providing education and guidance can reduce stress and enhance understanding of the chaotic events confronting our nation. It also provides a platform for communication and exploration should additional terrorist attacks or acts of war occur. It is important to examine how to approach children and adolescents to communicate with them about these sensitive issues.

Policy implications of medical tourism development in destination countries: revisiting and revising an existing framework by examining the case of Jamaica.

PubMed

Johnston, Rory; Crooks, Valorie A; Ormond, Meghann

2015-07-04

Medical tourism is now targeted by many hospitals and governments worldwide for further growth and investment. Southeast Asia provides what is perhaps the best documented example of medical tourism development and promotion on a regional scale, but interest in the practice is growing in locations where it is not yet established. Numerous governments and private hospitals in the Caribbean have recently identified medical tourism as a priority for economic development. We explore here the projects, activities, and outlooks surrounding medical tourism and their anticipated economic and health sector policy implications in the Caribbean country of Jamaica. Specifically, we apply Pocock and Phua's previously-published conceptual framework of policy implications raised by medical tourism to explore its relevance in this new context and to identify additional considerations raised by the Jamaican context. Employing case study methodology, we conducted six weeks of qualitative fieldwork in Jamaica between October 2012 and July 2013. Semi-structured interviews with health, tourism, and trade sector stakeholders, on-site visits to health and tourism infrastructure, and reflexive journaling were all used to collect a comprehensive dataset of how medical tourism in Jamaica is being developed. Our analytic strategy involved organizing our data within Pocock and Phua's framework to identify overlapping and divergent issues. Many of the issues identified in Pocock and Phua's policy implications framework are echoed in the planning and development of medical tourism in Jamaica. However, a number of additional implications, such as the involvement of international development agencies in facilitating interest in the sector, cyclical mobility of international health human resources, and the significance of health insurance portability in driving the growth of international hospital accreditation, arise from this new context and further enrich the original framework. The framework developed by Pocock and Phua is a flexible common reference point with which to document issues raised by medical tourism in established and emerging destinations. However, the framework's design does not lend itself to explaining how the underlying health system factors it identifies work to facilitate medical tourism's development or how the specific impacts of the practice are likely to unfold.

The ethics of molecular memory modification.

PubMed

Hui, Katrina; Fisher, Carl E

2015-07-01

Novel molecular interventions have recently shown the potential to erase, enhance and alter specific long-term memories. Unique features of this form of memory modification call for a close examination of its possible applications. While there have been discussions of the ethics of memory modification in the literature, molecular memory modification (MMM) can provide special insights. Previously raised ethical concerns regarding memory enhancement, such as safety issues, the 'duty to remember', selfhood and personal identity, require re-evaluation in light of MMM. As a technology that exploits the brain's updating processes, MMM helps correct the common misconception that memory is a static entity by demonstrating how memory is plastic and subject to revision even in the absence of external manipulation. Furthermore, while putatively safer than other speculative technologies because of its high specificity, MMM raises notable safety issues, including potential insidious effects on the agent's emotions and personal identity. Nonetheless, MMM possesses characteristics of a more permissible form of modification, not only because it is theoretically safer, but because its unique mechanism of action requires a heightened level of cooperation from the agent. Discussions of memory modification must consider the specific mechanisms of action, which can alter the weight and relevance of various ethical concerns. MMM also highlights the need for conceptual accuracy regarding the term 'enhancement'; this umbrella term will have to be differentiated as new technologies are applied to a widening array of purposes. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Teacher to Teacher: What Texts Effectively Raise Issues Related to 9/11 for Secondary Students?

ERIC Educational Resources Information Center

English Journal, 2006

2006-01-01

This article deals with texts that effectively raise issues related to 9/11 for secondary students, as discussed by several teachers. Kevin J. Collins from St. Thomas Aquinas High School says, "Elephant," Gus Van Sant's exploration of a Columbine-like tragedy, underscores the current generation's attempt to define the meaning of events in…

Internet Cancer Support Groups

PubMed Central

Chee, Wonshik; Tsai, Hsiu-Min; Lin, Li-Chen; Cheng, Ching-Yu

2006-01-01

Internet Cancer Support Groups (ICSGs) are an emerging form of support group on Internet specifically for cancer patients. Previous studies have indicated the effectiveness of ICSGs as a research setting or a data-collection method. Yet recent studies have also indicated that ICSGs tend to serve highly educated, high-income White males who tend to be at an early stage of cancer. In this article, a total of 317 general ICSGs and 229 ethnic-specific ICSGs searched through Google.com, Yahoo.com, http://Msn.com, AOL.com, and ACOR.org are analyzed from a feminist perspective. The written records of group discussions and written memos by the research staff members were also analyzed using content analysis. The idea categories that emerged about these groups include (a) authenticity issues; (b) ethnicity and gender issues; (c) intersubjectivity issues; and (d) potential ethical issues. The findings suggest that (a) researchers adopt multiple recruitment strategies through various Internet sites and/or real settings; (b) researchers raise their own awareness of the potential influences of the health-related resources provided by ICSGs and regularly update their knowledge related to the federal and state standards and/or policies related to ICSGs; and (c) researchers consider adopting a quota-sampling method. PMID:15681976

Raising venture capital in the biopharma industry.

PubMed

Leytes, Lev J

2002-11-15

Raising venture capital (VC) is both an art and a science. Future entrepreneurs should carefully consider the various issues of VC financing that have a strong impact on the success of their business. In addition to attracting the best venture capital firms, these issues include such subtle but important points as the timing of financing (especially of the first round), external support sources, desirable qualities of a VC firm, amount to be raised, establishing a productive interface between the founders and the venture capitalists, and most importantly the effects of well-executed VC funding on hiring senior executives and scientific leaders.

Chimeric antigen receptor for adoptive immunotherapy of cancer: latest research and future prospects.

PubMed

Shi, Huan; Sun, Meili; Liu, Lin; Wang, Zhehai

2014-09-21

Chimeric antigen receptors (CARs) are recombinant receptors that combine the specificity of an antigen-specific antibody with the T-cell's activating functions. Initial clinical trials of genetically engineered CAR T cells have significantly raised the profile of T cell therapy, and great efforts have been made to improve this approach. In this review, we provide a structural overview of the development of CAR technology and highlight areas that require further refinement. We also discuss critical issues related to CAR therapy, including the optimization of CAR T cells, the route of administration, CAR toxicity and the blocking of inhibitory molecules.

What kinds of conservatives does social psychology lack, and why?

PubMed

Ross, Lee

2015-01-01

Although Duarte et al.'s claims about the potential benefits of greater political diversity in the ranks of social psychology are apt, their discussion of the decline in such diversity, the role played by self-selection, and the specific domains they cite in discussing an anti-conservative bias raise issues that merit closer examination. The claim that sound research and analysis challenging liberal orthodoxies fails to receive a fair hearing in our journals and professional discourse is also disputed.

Science Overview: The LTTG Technology Review Meeting March 2006 Summary Report

NASA Technical Reports Server (NTRS)

Bruning, Claus; Ko, Malcolm; Lee, David; Miake-Lye, Richard

2006-01-01

This report presents an overview of the latest scientific consensus understanding of the effect of aviation emissions on the atmosphere for both local air quality and climate change in order to provide a contextual framework for raising future questions to help assess the environmental benefits of technology goals. Although studies of the two issues share a common framework (of quantifying the emissions, the change in concentrations in the atmosphere, and the environmental impacts), the communities of practitioners are distinctly different. The scientific community will continue to provide guidelines on trade-off among different contributors to a specific environmental impact, such as global climate, or local air quality. Ultimately, monetization of the costs and benefits of mitigation actions is the proper tool for quantifying and analyzing trade-offs between the two issues. Scientific assessment of the impacts and their uncertainties are critical inputs to these analyses. Until environmental effects of aviation emerge as a policy driven issue, there is little incentive within the scientific community to focus on research efforts specific to trade-off studies between local and global impacts.

Children's Difficulty with Raising: A Performance Account

ERIC Educational Resources Information Center

Choe, Jinsun; Deen, Kamil

2016-01-01

This article explores English-speaking children's acquisition of raising structures with an experiencer (e.g.," John seems to Mary to be happy"). We review and address previously unnoticed issues in the methodologies of existing studies testing the acquisition of raising, thus providing a more reliable picture of children's abilities…

Funding and Philosophy: A Conversation About Band Trips and Fund Raising.

ERIC Educational Resources Information Center

Hoffer, Charles R.

1992-01-01

A hypothetical conversation between Thoughtful Principal and Music Teacher raises some basic issues about fund raising, booster activities, and band trips. Considerations about contest criteria, door-to-door selling, student costs, support for nonband musical programs, and the educational and motivational value of band trips are discussed. (MLH)

[Discussion on solutions to ethical issues of clinical researches in a real world].

PubMed

Wang, Si-Cheng; Liu, Bao-Yan; Xiong, Ning-Ning; Xie, Qi; Zhang, Run-Shun; Zhou, Xue-Zhong; Qiao, Jie

2013-04-01

The paradigm of a real world study has become the frontiers of clinical researches, especially in the field of Chinese medicine, all over the world in recent years. In this paper, ethical issues which probably exist in real-world studies are raised and reviewed. Moreover, some preliminary solutions to these issues such as protecting subjects during the process of real-world studies and performing ethical review are raised based on recent years' practices to enhance the scientificity and ethical level of real-world studies.

Ethical aspects of malaria control and research.

PubMed

Jamrozik, Euzebiusz; de la Fuente-Núñez, Vânia; Reis, Andreas; Ringwald, Pascal; Selgelid, Michael J

2015-12-22

Malaria currently causes more harm to human beings than any other parasitic disease, and disproportionally affects low-income populations. The ethical issues raised by efforts to control or eliminate malaria have received little explicit analysis, in comparison with other major diseases of poverty. While some ethical issues associated with malaria are similar to those that have been the subject of debate in the context of other infectious diseases, malaria also raises distinct ethical issues in virtue of its unique history, epidemiology, and biology. This paper provides preliminary ethical analyses of the especially salient issues of: (i) global health justice, (ii) universal access to malaria control initiatives, (iii) multidrug resistance, including artemisinin-based combination therapy (ACT) resistance, (iv) mandatory screening, (v) mass drug administration, (vi) benefits and risks of primaquine, and (vii) malaria in the context of blood donation and transfusion. Several ethical issues are also raised by past, present and future malaria research initiatives, in particular: (i) controlled infection studies, (ii) human landing catches, (iii) transmission-blocking vaccines, and (iv) genetically-modified mosquitoes. This article maps the terrain of these major ethical issues surrounding malaria control and elimination. Its objective is to motivate further research and discussion of ethical issues associated with malaria--and to assist health workers, researchers, and policy makers in pursuit of ethically sound malaria control practice and policy.

Commercial activities and the promotion of health in schools.

PubMed

Raine, Gary

2013-11-01

Many companies nowadays consider schools to be an important setting for marketing to children. However, important concerns can be raised from a health promotion perspective about the potential negative impact of commercial activities on the health and well-being of pupils. As this discussion paper will demonstrate, some commercial activities raise concerns in relation to physical health and obesity, not only by potentially undermining formal curriculum messages, but also through the active promotion of specific products, particularly those high in fat, sugar or salt. Nonetheless, the issues raised by commercial activities are not solely limited to effects on physical health. By allowing commercial activities, schools risk instilling in pupils consumer-orientated values. This is significant as such values have been linked to the development of poor health and well-being. Furthermore, the presence in schools of commercial activities will also militate against informed decision-making and be disempowering. There is also evidence that business-sponsored teaching materials can contain biased and misleading information. The potential negative impacts of commercial activities are inconsistent with goals in relation to the promotion of health and the principles of health-promoting schools.

Science and ethics of human immunodeficiency virus/acquired immunodeficiency syndrome controversies in Africa.

PubMed

Brewster, David

2011-09-01

The human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) epidemic in Africa has raised important ethical issues for both researchers and clinicians. The most notorious controversy has been related to the zidovudine (AZT) trials in Africa in the late 1990s, in which the control groups were given a placebo rather than an effective drug to prevent vertical transmission. This raised concerns in the sponsoring country about exploitation of subjects, injustice and an ethical double standard between donor countries and resource-poor settings. However, the real double standard is between clinical practice standards in Western versus African countries, which must be addressed as part of the increasing global inequity of wealth both between countries and also within countries. There are important limitations to ethical declarations, principles and guidelines on their own without contextual ethical reasoning. The focus on research ethics with the HIV epidemic has led to a relative neglect of ethical issues in clinical practice. Although the scientific advances in HIV/AIDS have changed the ethical issues since the 1990s, there has also been progress in the bioethics of HIV/AIDS in terms of ethical review capability by local committees as well as in exposure to ethical issues by clinicians and researchers in Africa. However, serious concerns remain about the overregulation of research by bureaucratic agencies which could discourage African research on specifically African health issues. There is also a need for African academic institutions and researchers to progressively improve their research capacity with the assistance of research funders and donor agencies. © 2011 The Author. Journal of Paediatrics and Child Health © 2011 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

Managing diversity and European policy: Towards a typology for sport pedagogy.

PubMed

Dinold, Maria; Diketmüller, Rosa; Grix, Jonathan; Phillpots, Lesley

2013-01-01

This article adds to the growing body of knowledge in sport pedagogy and focuses specifically upon the intersection of gender and disability. Its purpose is twofold, to create a typology for examining good practice in sport pedagogy that is reflective and inclusive and raises awareness of the diverse needs of all participants in physical activity 'regardless' of gender and ability for all children. We acknowledge that access to physical activity, education and sport are complex and multifaceted, however, the main purpose of this paper is to raise awareness of 'diversity' by focusing specifically upon the role of gender and ability. Through an examination of gender and disability policies in official European Union (EU) policy documents and commercial examples of policy-in-practice we propose a typology for diversity and diversity management. A close look at EU level is instructive because national policies of the member countries vary a lot with respect to diversity issues but should be in accordance in the main areas. Such a reading enables the building of a typology of recommendations for how such policy can be rendered in sport pedagogy practice. We suggest six significant, but related principles that include (1) mainstreaming; (2) teaching and coaching sensitive to difference; (3) empowerment; (4) inclusion; (5) adaptation; and (6) inner differentiation. This holistic typology seeks to 'mainstream' issues of gender and disability policy by providing a set of principles that can be applied to a range of teaching and coaching settings.

Safety Communication Tools and Healthcare Professionals' Awareness of Specific Drug Safety Issues in Europe: A Survey Study.

PubMed

de Vries, Sieta T; van der Sar, Maartje J M; Coleman, Anna Marie; Escudero, Yvette; Rodríguez Pascual, Alfonso; Maciá Martínez, Miguel-Ángel; Cupelli, Amelia; Baldelli, Ilaria; Šipić, Ivana; Andrić, Adriana; Michan, Line; Denig, Petra; Mol, Peter G M

2018-07-01

National competent authorities (NCAs) use Direct Healthcare Professional Communications (DHPCs) to communicate new drug safety issues to healthcare professionals (HCPs). More knowledge is needed about the effectiveness of DHPCs and the extent to which they raise awareness of new safety issues among HCPs. The objective was to assess and compare general practitioners' (GPs'), cardiologists', and pharmacists' familiarity with DHPCs as communication tools, their awareness of specific drug safety issues, and the sources through which they had become aware of the specific issues. GPs, cardiologists, and pharmacists from nine European countries (Croatia, Denmark, Ireland, Italy, the Netherlands, Norway, Spain, Sweden, and the UK) completed a web-based survey. The survey was conducted in the context of the Strengthening Collaboration for Operating Pharmacovigilance in Europe (SCOPE) Joint Action. Respondents were asked about their familiarity with DHPCs in general and their awareness of safety issues that had recently been communicated and involved the following drugs: combined hormonal contraceptives, diclofenac, valproate, and ivabradine. Those HCPs who were aware of the specific safety issues were subsequently asked to indicate the source through which they had become aware of them. Differences between professions in familiarity with DHPCs and awareness were tested using a Pearson χ 2  test per country and post hoc Pearson χ 2  tests in the case of statistically significant differences. Of the 3288 included respondents, 54% were GPs, 40% were pharmacists, and 7% were cardiologists. The number of respondents ranged from 67 in Denmark to 916 in Spain. Most respondents (92%) were familiar with DHPCs, with one significant difference between the professions: pharmacists were more familiar than GPs in Italy (99 vs 90%, P = 0.004). GPs' awareness ranged from 96% for the diclofenac issue to 70% for the ivabradine issue. A similar pattern was shown for pharmacists (91% aware of the diclofenac issue to 66% of the ivabradine issue). Cardiologists' awareness ranged from 91% for the ivabradine issue to 34% for the valproate issue. Overall, DHPCs were a common source through which GPs (range: 45% of those aware of the contraceptives issue to 60% of those aware of the valproate issue), cardiologists (range: 33% for the contraceptives issue to 61% for the valproate issue), and pharmacists (range: 41% for the contraceptives issue to 51% for the ivabradine issue) had become aware of the specific safety issues, followed by information on websites or in newsletters. GPs, cardiologists, and pharmacists were to a similar extent (highly) familiar with DHPCs, but they differed in awareness levels of specific safety issues. Cardiologists were less aware of safety issues associated with non-cardiology drugs even if these had cardiovascular safety concerns. This implies that additional strategies may be needed to reach specialists when communicating safety issues regarding drugs outside their therapeutic area but with risks related to their field of specialisation. DHPCs were an important source for the different professions to become aware of specific safety issues, but other sources were also often used. NCAs should consider the use of a range of sources when communicating important safety issues to HCPs.

Product Fund-Raising: A Practical Resource.

ERIC Educational Resources Information Center

Lemieux, Russell A.

1997-01-01

Reviews critical issues in selecting a product fund-raising program for schools. Suggests that the most important considerations should be the quality of the product or service and its "fit" with the school. (JDI)

A gower maneuver: the American Society for Bioethics and Humanities' resolution of the "Taking Stands" debate.

PubMed

Antommaria, Armand H Matheny

2004-01-01

The American Society for Bioethics and Humanities debated for several years about whether it should adopt positions and, if so, on what range of issues. The membership recently approved an amendment to its bylaws permitting the Society to adopt positions on matters related to academic freedom and professionalism but not on substantive moral and policy issues. This resolution is problematic for a number of reasons, including the lack of a categorical difference between these types of claims and the Society's inability to speak on behalf of patients and research subjects. The implementation of the amendment also raises several issues. The Society will need to refrain from speaking too specifically and to articulate the responsibilities of its members. If the Society fails to address these concerns, it runs the risk of denigrating its public image and that of the profession.

Co-Occurring Disorders in Substance Abuse Treatment: Issues and Prospects

PubMed Central

Flynn, Patrick M.; Brown, Barry S.

2008-01-01

This paper explores the epidemiology of co-occurring disorders with an emphasis on the implications of study findings for the functioning and potential of substance abuse treatment. Severity of disorder is discussed as an issue that may have particular significance for the selection of specialized as opposed to traditional substance abuse treatment forms. Exploration is made, as well, of the resources currently available to substance abuse treatment, especially the human resources available, and the implications of resource availability for undertaking initiatives specific to co-occurring disorder. Findings from standard and enhanced treatment for comorbid individuals are examined in an effort to clarify areas of need for specialized and typical treatment personnel. Issues are raised for consideration by the clinical research and treatment provider communities in terms of assessment and diagnosis, manpower and training, and response to the challenge of relapse in this population. PMID:17574791

Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations

PubMed Central

Gelinas, Luke; Pierce, Robin; Winkler, Sabune; Cohen, I. Glenn; Lynch, Holly Fernandez; Bierer, Barbara E.

2017-01-01

The use of social media as a recruitment tool for research with humans is increasing, and likely to continue to grow. Despite this, to date there has been no specific regulatory guidance and little in the bioethics literature to guide investigators and IRBs faced with navigating the ethical issues it raises. We begin to fill this gap by first defending a non-exceptionalist methodology for assessing social media recruitment; second, examining respect for privacy and investigator transparency as key norms governing social media recruitment; and, finally, analyzing three relatively novel aspects of social media recruitment: (i) the ethical significance of compliance with website ‘terms of use’; (ii) the ethics of recruiting from the online networks of research participants; and (iii) the ethical implications of online communication from and between participants. Two checklists aimed at guiding investigators and IRBs through the ethical issues are included as Appendices. PMID:28207365

Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations.

PubMed

Gelinas, Luke; Pierce, Robin; Winkler, Sabune; Cohen, I Glenn; Lynch, Holly Fernandez; Bierer, Barbara E

2017-03-01

The use of social media as a recruitment tool for research with humans is increasing, and likely to continue to grow. Despite this, to date there has been no specific regulatory guidance and there has been little in the bioethics literature to guide investigators and institutional review boards (IRBs) faced with navigating the ethical issues such use raises. We begin to fill this gap by first defending a nonexceptionalist methodology for assessing social media recruitment; second, examining respect for privacy and investigator transparency as key norms governing social media recruitment; and, finally, analyzing three relatively novel aspects of social media recruitment: (i) the ethical significance of compliance with website "terms of use"; (ii) the ethics of recruiting from the online networks of research participants; and (iii) the ethical implications of online communication from and between participants. Two checklists aimed at guiding investigators and IRBs through the ethical issues are included as appendices.

The Full Spectrum of Clinical Ethical Issues in Kidney Failure. Findings of a Systematic Qualitative Review.

PubMed

Kahrass, Hannes; Strech, Daniel; Mertz, Marcel

2016-01-01

When treating patients with kidney failure, unavoidable ethical issues often arise. Current clinical practice guidelines some of them, but lack comprehensive information about the full range of relevant ethical issues in kidney failure. A systematic literature review of such ethical issues supports medical professionalism in nephrology, and offers a solid evidential base for efforts that aim to improve ethical conduct in health care. To identify the full spectrum of clinical ethical issues that can arise for patients with kidney failure in a systematic and transparent manner. A systematic review in Medline (publications in English or German between 2000 and 2014) and Google Books (with no restrictions) was conducted. Ethical issues were identified by qualitative text analysis and normative analysis. The literature review retrieved 106 references that together mentioned 27 ethical issues in clinical care of kidney failure. This set of ethical issues was structured into a matrix consisting of seven major categories and further first and second-order categories. The systematically-derived matrix helps raise awareness and understanding of the complexity of ethical issues in kidney failure. It can be used to identify ethical issues that should be addressed in specific training programs for clinicians, clinical practice guidelines, or other types of policies dealing with kidney failure.

The Full Spectrum of Clinical Ethical Issues in Kidney Failure. Findings of a Systematic Qualitative Review

PubMed Central

Kahrass, Hannes; Strech, Daniel; Mertz, Marcel

2016-01-01

Background When treating patients with kidney failure, unavoidable ethical issues often arise. Current clinical practice guidelines some of them, but lack comprehensive information about the full range of relevant ethical issues in kidney failure. A systematic literature review of such ethical issues supports medical professionalism in nephrology, and offers a solid evidential base for efforts that aim to improve ethical conduct in health care. Aim To identify the full spectrum of clinical ethical issues that can arise for patients with kidney failure in a systematic and transparent manner. Method A systematic review in Medline (publications in English or German between 2000 and 2014) and Google Books (with no restrictions) was conducted. Ethical issues were identified by qualitative text analysis and normative analysis. Results The literature review retrieved 106 references that together mentioned 27 ethical issues in clinical care of kidney failure. This set of ethical issues was structured into a matrix consisting of seven major categories and further first and second-order categories. Conclusions The systematically-derived matrix helps raise awareness and understanding of the complexity of ethical issues in kidney failure. It can be used to identify ethical issues that should be addressed in specific training programs for clinicians, clinical practice guidelines, or other types of policies dealing with kidney failure. PMID:26938863

Investigating the origin of AIDS: some ethical dimensions

PubMed Central

Martin, B

2003-01-01

The theory that AIDS originated from contaminated polio vaccines raises a number of challenging issues with ethical dimensions. The Journal of Medical Ethics dealt with a submission about the theory a decade ago; subsequent developments have raised further issues. Four areas of contention are addressed: whether the theory should be investigated; whether anyone should be blamed; whether defamation actions are appropriate, and whether the scientific community has a responsibility to examine unorthodox theories. PMID:12930866

Your Genes, Your Choices: Exploring the Issues Raised by Genetic Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baker, C.

1999-05-31

Your Genes, Your Choices provides accurate information about the ethical, legal, and social implications of the Human Genome Project and genetic research in an easy-to-read style and format. Each chapter in the book begins with a brief vignette, which introduces an issue within a human story, and raises a question for the reader to think about as the basic science and information are presented in the rest of the chapter.

Evaluation in health promotion: thoughts from inside a human research ethics committee.

PubMed

Allen, Judy; Flack, Felicity

2015-12-01

Health promotion research, quality improvement and evaluation are all activities that raise ethical issues. In this paper, the Chair and a member of human resear ch ethics committees provide an insiders' point of view on how to demonstrate ethical conduct in health promotion research and quality improvement. Several common issues raised by health promotion research and evaluation are discussed including researcher integrity, conflicts of interest, use of information, consent and privacy.

The Child Abuse Matter and the Major Role Played by the Teacher: Issues Raised by a Pilot Focus Group Sample of Primary Teachers

ERIC Educational Resources Information Center

Vitalaki, Elena

2013-01-01

A great deal of attention is now being paid to issues raised by child abuse. Recent reports, enquiries and relevant agencies have all recognized the important role played by teachers in aiding the detection and prevention of child abuse, due to their close everyday contact with children. The result of the ideas presented in the present work was…

Staff Development for Raising Attainment: A Practitioner's View of What Works

ERIC Educational Resources Information Center

Bates, Sharon; Watt, Laura

2016-01-01

This paper offers a practitioner's view of how continuing professional development (CPD) can help raise achievement in schools. It is one of four papers in this issue linked to a research project in Stoke-on-Trent seeking to raise attainment in schools in deprived communicates. Based on over 20 years' experience working in and with different…

Towards the discovery of drug-like RNA ligands?

PubMed

Foloppe, Nicolas; Matassova, Natalia; Aboul-Ela, Fareed

2006-11-01

Targeting RNA with small molecule drugs is an area of great potential for therapeutic treatment of infections and possibly genetic and autoimmune diseases. However, a mature set of precedents and established methodology is lacking. The physicochemical properties of RNA raise specific issues and obstacles to development, and contribute to explain the distinct characteristics of natural RNA ligands, including antibiotics. Yet, RNA-targeting strategies are being implemented to reinvigorate antibacterial discovery by using the ribosomal X-ray structures to modify known antibiotics. To exploit further these structures, we suggest the use of existing protein kinase-directed libraries of drug-like compounds to target the A-site of the bacterial ribosome, on the basis of a specific structural hypothesis.

Issues in Peer Review.

ERIC Educational Resources Information Center

Sawamura, Mark H.

2001-01-01

Based on concerns raised at a workshop at the Southern California College of Optometry, addresses critical issues in the process of peer review of faculty teaching and possible alternatives to these issues as applied to an optometric institution. (EV)

Human cloning, stem cell research. An Islamic perspective.

PubMed

Al-Aqeel, Aida I

2009-12-01

The rapidly changing technologies that involve human subjects raise complex ethical, legal, social, and religious issues. Recent advances in the field of cloning and stem cell research have introduced new hopes for the treatment of serious diseases. But this promise has raised many complex questions. This field causes debate and challenge, not only among scientists but also among ethicists, religious scholars, governments, and politicians. There is no consensus on the morality of human cloning, even within specific religious traditions. In countries in which religion has a strong influence on political decision making, the moral status of the human embryo is at the center of the debate. Because of the inevitable consequences of reproductive cloning, it is prohibited in Islam. However, stem cell research for therapeutic purposes is permissible with full consideration, and all possible precautions in the pre-ensoulment stages of early fetus development, if the source is legitimate.

Comment: Spurious Correlation and Other Observations on Experimental Design for Engineering Dimensional Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piepel, Gregory F.

2013-08-01

This article discusses the paper "Experimental Design for Engineering Dimensional Analysis" by Albrecht et al. (2013, Technometrics). That paper provides and overview of engineering dimensional analysis (DA) for use in developing DA models. The paper proposes methods for generating model-robust experimental designs to supporting fitting DA models. The specific approach is to develop a design that maximizes the efficiency of a specified empirical model (EM) in the original independent variables, subject to a minimum efficiency for a DA model expressed in terms of dimensionless groups (DGs). This discussion article raises several issues and makes recommendations regarding the proposed approach. Also,more » the concept of spurious correlation is raised and discussed. Spurious correlation results from the response DG being calculated using several independent variables that are also used to calculate predictor DGs in the DA model.« less

Meditations on the Italian population of low interest to the vaccination campaign against the pandemic from H1N1v. The point of view of the region.

PubMed

Conversano, M; Battista, T; Cipriani, R; Sponselli, G M; Caputi, G; Calamai, C; Pesare, A

2011-09-01

In this article we developed a technical reflection on the organization of the National Pandemic Influenza A H1N1 variant plan, implemented in the Italian Region and in specific in the Local Health Agency Taranto. The audit has raised some critical issues that led to the limited success of the vaccination campaign. Among the critics it was really difficult to find quickly and easily those healthy individuals at risk for disease. Therefore it raises the need to prepare a special population register as an essential preliminary step necessary for the active call of the target population in anticipation of a possible pandemic wave. In this vein, the Prevention Department of Taranto has developed a recording database system that has been experienced during the influenza vaccination campaign for the 2010-2011 season.

Stem cells: science, policy, and ethics

PubMed Central

Fischbach, Gerald D.; Fischbach, Ruth L.

2004-01-01

Human embryonic stem cells offer the promise of a new regenerative medicine in which damaged adult cells can be replaced with new cells. Research is needed to determine the most viable stem cell lines and reliable ways to promote the differentiation of pluripotent stem cells into specific cell types (neurons, muscle cells, etc.). To create new cell lines, it is necessary to destroy preimplantation blastocysts. This has led to an intense debate that threatens to limit embryonic stem cell research. The profound ethical issues raised call for informed, dispassionate debate. PMID:15545983

Current status of psychology and clinical psychology in India - an appraisal.

PubMed

Virudhagirinathan, Baboo Sankar; Karunanidhi, Subbiah

2014-10-01

This paper provides an overview of the social and cultural context for the emergence and development of psychology in India and also more specifically of the development of clinical psychology. It details the range of universities offering psychology programmes and the various bodies involved in supporting the development of the psychology. The paper also describes the development of clinical psychology in India and the variety of roles undertaken by clinical psychologists. Finally, it raises a number of issues facing the development of Indian psychology into the future.

Mineralogy and Morphology of Amphiboles Observed in Soils and Rocks in El Dorado Hills, California

USGS Publications Warehouse

Meeker, G.P.; Lowers, H.A.; Swayze, G.A.; Van Gosen, B. S.; Sutley, S.J.; Brownfield, I.K.

2006-01-01

From the Executive Summary: At the request of the U.S. Environmental Protection Agency (USEPA), the U.S. Geological Survey (USGS) has conducted an independent study of amphiboles in rocks and soils in the El Dorado Hills, California, area. The purpose of this study is to investigate specific issues regarding the presence of 'naturally occurring asbestos' raised by an USEPA activity-based sampling study and subsequent criticisms of that study outlined in a review prepared by The R.J. Lee Group (RJLG).

Recent Developments at DG Competition: 2016/2017.

PubMed

Buehler, Benno; Coublucq, Daniel; Hariton, Cyril; Langus, Gregor; Valletti, Tommaso

2017-01-01

The Directorate General for Competition at the European Commission enforces competition law in the areas of antitrust, merger control, and state aids. This year's article provides first a general presentation of the role of the Chief Competition Economist's team and surveys the main achievements of the Directorate General for Competition over 2016/2017. The article then reviews the economic work undertaken in one merger case between Dow/DuPont, which raised specific issues related to innovation, as well as in an antitrust case on parity clauses related to Amazon e-books.

Cross-functional systems

NASA Technical Reports Server (NTRS)

Lee, Mark

1991-01-01

Many companies, including Xerox and Texas Instruments, are using cross functional systems to deal with the increasingly complex and competitive business environment. However, few firms within the aerospace industry appear to be aware of the significant benefits that cross functional systems can provide. Those benefits are examined and a flexible methodology is discussed that companies can use to identify and develop cross functional systems that will help improve organizational performance. In addition, some of the managerial issues are addressed that cross functional systems may raise and specific examples are used to explore networking's contributions to cross functional systems.

Ethical Issues Surrounding the Use of Modern Human Remains for Research in South Africa.

PubMed

Briers, N; Dempers, J J

2017-02-01

Chapter 8 of the South African National Health Act 61 of 2003 (NHA) that deals with the donation of human tissue was promulgated in 2012. The new Act is perceived to impose restrictions on low-risk research involving human remains. This study aimed to identify the issues raised by a research ethics committee (REC) when reviewing protocols where human remains are used as data source. REC minutes from 2009 to 2014 were reviewed, and issues raised by the committee were categorized. In total, 127 protocols submitted to the committee over 6 years involved human remains. Queries relating to science (22.2%) and administration (18.9%) were the most common, whereas queries relating to legal issues constituted only 10.2%. Ethical issues centered on informed consent regarding sensitive topics such as HIV, DNA, and deceased children. The change in legislation did not change the number or type of legal issues identified by the REC.

Unique issues raised by drug benefit design.

PubMed

Berndt, Ernst R

2004-01-01

In this Perspective on the preceding paper by Joseph Newhouse, I point out a number of features of the pharmaceutical industry that differentiate it from other health care sectors. These differences help explain why it has proved to be so very difficult to construct policies that simultaneously contain health care costs, provide patients with high-quality care, and generate continued incentives for innovation. I then summarize Newhouse's preferred Medicare prescription drug benefit program and the issues it raises.

JPRS Report. Environmental Issues.

DTIC Science & Technology

1991-06-11

the aspects of management of raising, artificial repro- duction, artificial insemination , raising of the young, male reproduction capability...method of fresh sperm artificial insemination to impreg- nate pandas. In 1980 Mei Mei, a panda in the Chengdu Zoo, success- fully gave birth to a... insemination for panda reproduction. Beginning in 1980, in 10 years of artificially raising giant pandas, the Chengdu Zoo has had 15 pregnancies

Research Issues in Information Access.

ERIC Educational Resources Information Center

Molholt, Pat

1989-01-01

Discusses traditional library approaches to access to information and the possible impact of information technologies, library automation, and artificial intelligence. Access issues raised by these technologies are identified and a research agenda to explore these issues is outlined. (31 references) (CLB)

Treatment fidelity and research on Eye Movement Desensitization and Reprocessing (EMDR).

PubMed

Rosen, G M

1999-01-01

Eye Movement Desensitization and Reprocessing was introduced by Frances Shapiro (1989) as a treatment for posttraumatic stress disorder. When controlled studies failed to support the extraordinarily positive findings and claims made by Shapiro, proponents of EMDR raised the issue of treatment fidelity and criticized researchers for being inadequately trained. This paper considers the issues raised by EMDR proponents. It is concluded that treatment fidelity has been used as a specious, distracting issue that permits the continued promotion of EMDR in the face of negative empirical findings. Clinical psychologists are urged to remember the basic tenets of science when evaluating extraordinary claims made for novel techniques.

Library learning space--empirical research and perspective.

PubMed

Littleton, Dawn; Rethlefsen, Melissa

2008-01-01

Navigate the Net columns offer navigation to Web sites of value to medical librarians. For this issue, the authors recognize that librarians are frequently challenged to justify the need for the physical space occupied by a library in the context of the wide availability of electronic resources, ubiquitous student laptops, and competition for space needed by other institutional priorities. While this trend started years ago, it continues to raise a number of important practical and philosophical questions for libraries and the institutions they serve. What is the library for? What is library space best used for? How does the concept of "Library as Place" support informed decisions for librarians and space planners? In this issue, Web-based resources are surveyed that address these questions for libraries generally and health sciences libraries more specifically.

77 FR 45377 - Certain Light-Emitting Diodes and Products Containing the Same; Notice of Request for Statements...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-31

...Notice is hereby given that the presiding administrative law judge has issued a Final Initial Determination and a Recommended Determination on Remedy and Bonding in the above-captioned investigation. The Commission is soliciting comments on public interest issues raised by the recommended relief, specifically, a limited exclusion order (``LEO'') against light-emitting diodes (``LEDs'') found to infringe claims 1, 3, 4, 6, 8, 22, 24, 25, 26, 29, 32, 33, and 34 of U.S. Patent No. 7,151,283 that are manufactured or imported by LG Electronics, Inc. of Seoul, Republic of Korea; LG Innotek Co., Ltd. of Seoul, Republic of Korea; LG Electronics U.S.A., Inc. of Englewood Cliffs, New Jersey; and LG Innotek U.S.A., Inc. of San Diego, California.

83 FR 22712 - Certain Non-Volatile Memory Devices and Products Containing the Same; Notice of Request for...

Federal Register 2010, 2011, 2012, 2013, 2014

2018-05-16

...Notice is hereby given that the presiding administrative law judge has issued a Final Initial Determination and Recommended Determination on Remedy and Bonding in the above-captioned investigation. The Commission is soliciting comments on public interest issues raised by the recommended relief, specifically a limited exclusion order directed to respondents Toshiba Corporation of Tokyo, Japan; Toshiba Memory Corporation of Tokyo, Japan; Toshiba America, Inc. of New York, New York; Toshiba America Electronic Components, Inc. of Irvine, California; Toshiba America Information Systems, Inc. of Irvine, California; and Toshiba Information Equipment (Philippines), Inc. of Binan, Philippines, and cease and desist orders directed to the domestic respondents. This notice is soliciting public interest comments from the public only. Parties are to file public interest submissions pursuant to Commission rules.

Challenges in global ballast water management.

PubMed

Endresen, Øyvind; Lee Behrens, Hanna; Brynestad, Sigrid; Bjørn Andersen, Aage; Skjong, Rolf

2004-04-01

Ballast water management is a complex issue raising the challenge of merging international regulations, ship's specific configurations along with ecological conservation. This complexity is illustrated in this paper by considering ballast water volume, discharge frequency, ship safety and operational issues aligned with regional characteristics to address ecological risk for selected routes. A re-estimation of ballast water volumes gives a global annual level of 3500 Mton. Global ballast water volume discharged into open sea originating from ballast water exchange operations is estimated to approximately 2800 Mton. Risk based decision support systems coupled to databases for different ports and invasive species characteristics and distributions can allow for differentiated treatment levels while maintaining low risk levels. On certain routes, the risk is estimated to be unacceptable and some kind of ballast water treatment or management should be applied.

Before the experts arrive.

PubMed

Chandley, M

2001-06-01

This article addresses the rare event of the hostage situation in a forensic psychiatric nursing setting. It has a specific focus on the initial response and the accompanying issues for nurses at the clinical interface as the situation emerges. The intention of this article is to both offer guidance and raise the profile of this unique management issue because little attention is drawn to early-stage hostage situations at an organizational level. When a hostage situation occurs, inadequate preparation can mean the difference between life and death for the hostage, negotiator, or hostage taker. This article provides an overview of the relevant literature and offers guidance about the actions required when a nurse suddenly becomes responsible for managing the early stages of such a traumatic event. Responses, safety, and communication factors concerning the hostage taker are covered.

Multicultural Education: Issues and Perspectives. 6th Edition

ERIC Educational Resources Information Center

Banks, James A.; Banks, Cherry A. McGee

2006-01-01

Today's classrooms are more diverse than ever before. In order to reach these students, educators must be aware of the issues facing their various cultural, racial, ethnic, and language groups. Focusing on the pertinent issues in multicultural education, this new edition raises these critical issues and facilitates meaningful discussion. It has…

Adult Literacy and Basic Skills Unit (ALBSU) Newsletter, 1992.

ERIC Educational Resources Information Center

Adult Literacy and Basic Skills Unit (ALBSU) Newsletter, 1992

1992-01-01

This document consists of the four issues of this serial issued during 1992. Issue number 44 contains five articles: "Concerns and Fears" (issues raised by the proposed Further and Higher Education Bill in Britain); "Speaking Out for Wordpower" (Kay); "An Open Door to Mathematics" (Hay); "Literacy Problems and…

Quality and security - They work together

NASA Technical Reports Server (NTRS)

Carr, Richard; Tynan, Marie; Davis, Russell

1991-01-01

This paper describes the importance of considering computer security as part of software quality assurance practice. The intended audience is primarily those professionals involved in the design, development, and quality assurance of software. Many issues are raised which point to the need ultimately for integration of quality assurance and computer security disciplines. To address some of the issues raised, the NASA Automated Information Security program is presented as a model which may be used for improving interactions between the quality assurance and computer security community of professionals.

Considerations for setting the specifications of vaccines.

PubMed

Minor, Philip

2012-05-01

The specifications of vaccines are determined by the particular product and its method of manufacture, which raise issues unique to the vaccine in question. However, the general principles are shared, including the need to have sufficient active material to immunize a very high proportion of recipients, an acceptable level of safety, which may require specific testing or may come from the production process, and an acceptable low level of contamination with unwanted materials, which may include infectious agents or materials used in production. These principles apply to the earliest smallpox vaccines and the most recent recombinant vaccines, such as those against HPV. Manufacturing development includes more precise definitions of the product through improved tests and tighter control of the process parameters. Good manufacturing practice plays a major role, which is likely to increase in importance in assuring product quality almost independent of end-product specifications.

Theoretical frameworks used to discuss ethical issues in private physiotherapy practice and proposal of a new ethical tool.

PubMed

Drolet, Marie-Josée; Hudon, Anne

2015-02-01

In the past, several researchers in the field of physiotherapy have asserted that physiotherapy clinicians rarely use ethical knowledge to solve ethical issues raised by their practice. Does this assertion still hold true? Do the theoretical frameworks used by researchers and clinicians allow them to analyze thoroughly the ethical issues they encounter in their everyday practice? In our quest for answers, we conducted a literature review and analyzed the ethical theoretical frameworks used by physiotherapy researchers and clinicians to discuss the ethical issues raised by private physiotherapy practice. Our final analysis corpus consisted of thirty-nine texts. Our main finding is that researchers and clinicians in physiotherapy rarely use ethical knowledge to analyze the ethical issues raised in their practice and that gaps exist in the theoretical frameworks currently used to analyze these issues. Consequently, we developed, for ethical analysis, a four-part prism which we have called the Quadripartite Ethical Tool (QET). This tool can be incorporated into existing theoretical frameworks to enable professionals to integrate ethical knowledge into their ethical analyses. The innovative particularity of the QET is that it encompasses three ethical theories (utilitarism, deontologism, and virtue ethics) and axiological ontology (professional values) and also draws on both deductive and inductive approaches. It is our hope that this new tool will help researchers and clinicians integrate ethical knowledge into their analysis of ethical issues and contribute to fostering ethical analyses that are grounded in relevant philosophical and axiological foundations.

Effects of muscle atrophy on motor control

NASA Technical Reports Server (NTRS)

Stuart, D. G.

1985-01-01

As a biological tissue, muscle adapts to the demands of usage. One traditional way of assessing the extent of this adaptation has been to examine the effects of an altered-activity protocol on the physiological properties of muscles. However, in order to accurately interpret the changes associated with an activity pattern, it is necessary to employ an appropriate control model. A substantial literature exists which reports altered-use effects by comparing experimental observations with those from animals raised in small laboratory cages. Some evidence suggests that small-cage-reared animals actually represent a model of reduced use. For example, laboratory animals subjected to limited physical activity have shown resistance to insulin-induced glucose uptake which can be altered by exercise training. This project concerned itself with the basic mechanisms underlying muscle atrophy. Specifically, the project addressed the issue of the appropriateness of rats raised in conventional-sized cages as experimental models to examine this phenomenon. The project hypothesis was that rats raised in small cages are inappropriate models for the study of muscle atrophy. The experimental protocol involved: 1) raising two populations of rats, one group in conventional (small)-sized cages and the other group in a much larger (133x) cage, from weanling age (21 days) through to young adulthood (125 days); 2) comparison of size- and force-related characteristics of selected test muscles in an acute terminal paradigm.

Space Weather Concerns for All-Electric Propulsion Satellites

NASA Astrophysics Data System (ADS)

Horne, Richard B.; Pitchford, David

2015-08-01

The introduction of all-electric propulsion satellites is a game changer in the quest for low-cost access to space. It also raises new questions for satellite manufacturers, operators, and the insurance industry regarding the general risks and specifically the threat of adverse space weather. The issues surrounding this new concept were discussed by research scientists and up to 30 representatives from the space industry at a special meeting at the European Space Weather Week held in November 2014. Here we report on the discussions at that meeting. We show that for a satellite undergoing electric orbit raising for 200 days the radiation dose due to electrons is equivalent to approximately 6.7 year operation at geostationary orbit or approximately half the typical design life. We also show that electrons can be injected into the slot region (8000 km) where they pose a risk of satellite internal charging. The results highlight the importance of additional radiation protection. We also discuss the benefits, the operational considerations, the other risks from the Van Allen radiation belts, the new business opportunities for space insurance, and the need for space situation awareness in medium Earth orbit where electric orbit raising takes place.

Continuing professional development: issues raised by nurses and allied health professionals working in musculoskeletal settings.

PubMed

Haywood, Hannah; Pain, Helen; Ryan, Sarah; Adams, Jo

2013-09-01

Nurses and allied health professionals (AHPs) are required to evidence their engagement in continuing professional development (CPD) in order to retain their professional registration. Many challenges to CPD are reported, but little literature has explored pertinent CPD issues for clinicians with specialist roles or working in specialist services. No literature to date has explored the perceptions of CPD held by patients who receive these specialist services. Three focus groups and two conference calls were conducted with nurses, physiotherapists, podiatrists and occupational therapists who work in musculoskeletal (MSK) services; managers of these services; and people who use MSK services. These focus groups aimed: to explore the CPD needs and issues for this group of clinicians; to explore the perceptions of CPD held by people who have MSK conditions; and to compare the above with current literature to discern any factors specific to MSK settings. The focus groups and conference calls were audio-recorded. The recordings were coded by the researchers using a priori and inductive coding. The main issues discussed were: funding and time for CPD, providing examples of ways to provide CPD in spite of the challenges faced; that CPD needs changed with level of experience; initiatives by clinical specialists to reduce professional isolation; and future trends in CPD, including concerns about succession planning. The views of people with MSK conditions demonstrated an emphasis on communication skills that was seldom raised by managers and clinicians. Sufficient time, funding and provision of study leave were key to facilitating CPD activity for nurses and AHPs working in MSK services. People with MSK conditions particularly valued health professionals who combined good listening and communication skills with an attempt to understand what it was like to live with their condition. Copyright © 2012 John Wiley & Sons, Ltd.

Development of a software safety process and a case study of its use

NASA Technical Reports Server (NTRS)

Knight, John C.

1993-01-01

The goal of this research is to continue the development of a comprehensive approach to software safety and to evaluate the approach with a case study. The case study is a major part of the project, and it involves the analysis of a specific safety-critical system from the medical equipment domain. The particular application being used was selected because of the availability of a suitable candidate system. We consider the results to be generally applicable and in no way particularly limited by the domain. The research is concentrating on issues raised by the specification and verification phases of the software lifecycle since they are central to our previously-developed rigorous definitions of software safety. The theoretical research is based on our framework of definitions for software safety. In the area of specification, the main topics being investigated are the development of techniques for building system fault trees that correctly incorporate software issues and the development of rigorous techniques for the preparation of software safety specifications. The research results are documented. Another area of theoretical investigation is the development of verification methods tailored to the characteristics of safety requirements. Verification of the correct implementation of the safety specification is central to the goal of establishing safe software. The empirical component of this research is focusing on a case study in order to provide detailed characterizations of the issues as they appear in practice, and to provide a testbed for the evaluation of various existing and new theoretical results, tools, and techniques. The Magnetic Stereotaxis System is summarized.

Use of Genetic Testing for Primary Immunodeficiency Patients.

PubMed

Heimall, Jennifer R; Hagin, David; Hajjar, Joud; Henrickson, Sarah E; Hernandez-Trujillo, Hillary S; Tan, Yuval; Kobrynski, Lisa; Paris, Kenneth; Torgerson, Troy R; Verbsky, James W; Wasserman, Richard L; Hsieh, Elena W Y; Blessing, Jack J; Chou, Janet S; Lawrence, Monica G; Marsh, Rebecca A; Rosenzweig, Sergio D; Orange, Jordan S; Abraham, Roshini S

2018-04-01

Genetic testing plays a critical role in diagnosis for many primary immunodeficiency diseases. The goals of this report are to outline some of the challenges that clinical immunologists face routinely in the use of genetic testing for patient care. In addition, we provide a review of the types of genetic testing used in the diagnosis of PID, including their strengths and limitations. We describe the strengths and limitations of different genetic testing approaches for specific clinical contexts that raise concern for specific PID disorders in light of the challenges reported by the clinical immunologist members of the CIS in a recent membership survey. Finally, we delineate the CIS's recommendations for the use of genetic testing in light of these issues.

RESEARCH INTO EMERGING WASTE ISSUES

EPA Science Inventory

The purpose of this project is to investigate emerging waste issues. In particular, 2 issues have been raised in the last year that have major implications for the waste disposal industry: 1) waste gasification; and 2) proliferation of electronics waste.

APPCD loaned a h...

78 FR 77101 - Certain New Pneumatic Off-the-Road Tires From the People's Republic of China: Final Results of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-20

... Decision Memorandum and electronic versions of the Issues and Decision Memorandum are identical in content. Analysis of Comments Received All issues raised in this review are addressed in the Issues and Decision...

Ethical issues in cancer screening and prevention.

PubMed

Plutynski, Anya

2012-06-01

November 2009's announcement of the USPSTF's recommendations for screening for breast cancer raised a firestorm of objections. Chief among them were that the panel had insufficiently valued patients' lives or allowed cost considerations to influence recommendations. The publicity about the recommendations, however, often either simplified the actual content of the recommendations or bypassed significant methodological issues, which a philosophical examination of both the science behind screening recommendations and their import reveals. In this article, I discuss two of the leading ethical considerations at issue in screening recommendations: respect for patient autonomy and beneficence and then turn to the most significant methodological issues raised by cancer screening: the potential biases that may infect a trial of screening effectiveness, the problem of base rates in communicating risk, and the trade-offs involved in a judgment of screening effectiveness. These issues reach more broadly, into the use of "evidence-based" medicine generally, and have important implications for informed consent.

Context is everything: From cardiovascular disease to cerebral microbleeds.

PubMed

Charidimou, Andreas; Blacker, Deborah; Viswanathan, Anand

2018-01-01

Increasingly, our approach to cerebrovascular disease has become blurred by evidence published in literature often without careful consideration of what this evidence implies for specific patients at hand. In this essay, we analyze key contextual issues in cerebrovascular small vessel disease, in an attempt to highlight the symbolic gap that exists between research and clinical practice, a recurring theme in medicine. We highlight the importance of considering context when using data from epidemiologic, neuroimaging, and biomarker studies in determining relevance to the patient at hand. We argue, that while biomarkers and neuroimaging may eventually serve to help to identify individuals with specific cerebrovascular diseases, we must always continue to understand patients in a specific clinical context. These reflections are particularly relevant when considering cerebral microbleeds-a key marker of cerebrovascular small vessel disease whose detection often raises thorny clinical dilemmas.

Effects of pesticide chemicals on the activity of metabolic enzymes: focus on thiocarbamates.

PubMed

Mathieu, Cécile; Duval, Romain; Xu, Ximing; Rodrigues-Lima, Fernando; Dupret, Jean-Marie

2015-01-01

Thiocarbamates are chemicals widely used as pesticides. Occupational exposure is associated with acute intoxication. Populations can be exposed through food and water. Moreover, certain thiocarbamates are used clinically. The widespread use of thiocarbamates raises many issues regarding their toxicological and pharmacological impact. Thiocarbamates and their metabolites can modify biological macromolecules functions, in particular enzymes, through modification of cysteine residues, chelation of metal ions or modulation of the oxidative stress. Loss of enzyme activity can lead to the disruption of metabolic pathways, and explain, at least in part, the effects of these pesticides. Additionally, their reactivity and ability to easily cross biological barrier confer them a great interest for development of clinical applications. Many advances in the study of thiocarbamates metabolism and reactivity have led to a better knowledge of biological effects of these compounds. However, more data are needed on the determination of targets and specificity. Only few data concerning the exposure to a cocktail of pesticides/chemicals are available, raising the need to evaluate the toxic side effects of representative pesticides mixtures. Moreover, the dithiocarbamate Disulfiram has shown great potential in therapeutic applications and leads to the development of pharmacological thiocarbamates derivatives, highly specific to their target and easily distributed.

Challenges and dilemmas: fieldwork with upland minorities in socialist Vietnam, Laos and southwest China.

PubMed

Turner, Sarah

2010-01-01

The Chinese, Vietnamese and Lao spaces within the upland Southeast Asian massif, sheltering over 80 million people belonging to geographically dispersed and politically fragmented minority populations, have only recently reopened to overseas academic endeavours. Undertaking social sciences research there among ethnic minority groups is underscored by a specific set of challenges, dilemmas, and negotiations. This special issue brings together Western academics and post-fieldwork doctoral students from the realms of social anthropology and human geography, who have conducted in-depth fieldwork among ethnic minorities in upland southwest China, northern Vietnam, and southern Laos. The articles provide insights into the struggles and constraints they faced in the field, set against an understanding of the historical context of field research in these locales. In this unique context that nowadays interweaves economic liberalisation with centralised and authoritarian political structures, the authors explore how they have negotiated and manoeuvred access to ethnic minority voices in complex cultural configurations. The ethical challenges raised and methodological reflections offered will be insightful for others conducting fieldwork in the socialist margins of the Southeast Asian massif and beyond. This specific context is introduced here, followed by a critique of the literature on the core themes that contributors raise.

Teaching Gender Issues in Storytelling and in the College Teaching Class.

ERIC Educational Resources Information Center

Hanson, Trudy L.

An instructor, who teaches both graduate and undergraduate courses in storytelling, incorporates discussions of gender issues throughout the semester in various ways. In one course, class discussions are used to raise issues of the origin of Grimm's fairy tales and of story variants. Students are also encouraged to choose gender issues in…

Tracking: Conflicts and Resolutions. Controversial Issues in Education.

ERIC Educational Resources Information Center

Lockwood, Anne Turnbaugh

The educational tracking system raises highly controversial issues. This book offers both the viewpoints of researchers who have grappled with the issue of tracking and the personal experiences of school staff who have wrestled with the issue of whether or not to track instruction. It presents summaries of interviews that were conducted with three…

Implementing risk-stratified screening for common cancers: a review of potential ethical, legal and social issues

PubMed Central

Hall, A.E.; Chowdhury, S.; Hallowell, N.; Pashayan, N.; Dent, T.; Pharoah, P.; Burton, H.

2014-01-01

Background The identification of common genetic variants associated with common cancers including breast, prostate and ovarian cancers would allow population stratification by genotype to effectively target screening and treatment. As scientific, clinical and economic evidence mounts there will be increasing pressure for risk-stratified screening programmes to be implemented. Methods This paper reviews some of the main ethical, legal and social issues (ELSI) raised by the introduction of genotyping into risk-stratified screening programmes, in terms of Beauchamp and Childress's four principles of biomedical ethics—respect for autonomy, non-maleficence, beneficence and justice. Two alternative approaches to data collection, storage, communication and consent are used to exemplify the ELSI issues that are likely to be raised. Results Ultimately, the provision of risk-stratified screening using genotyping raises fundamental questions about respective roles of individuals, healthcare providers and the state in organizing or mandating such programmes, and the principles, which underpin their provision, particularly the requirement for distributive justice. Conclusions The scope and breadth of these issues suggest that ELSI relating to risk-stratified screening will become increasingly important for policy-makers, healthcare professionals and a wide diversity of stakeholders. PMID:23986542

To naturalize or not to naturalize? An issue for cognitive science as well as anthropology.

PubMed

Stenning, Keith

2012-07-01

Several of Beller, Bender, and Medin's (2012) issues are as relevant within cognitive science as between it and anthropology. Knowledge-rich human mental processes impose hermeneutic tasks, both on subjects and researchers. Psychology's current philosophy of science is ill suited to analyzing these: Its demand for ''stimulus control'' needs to give way to ''negotiation of mutual interpretation.'' Cognitive science has ways to address these issues, as does anthropology. An example from my own work is about how defeasible logics are mathematical models of some aspects of simple hermeneutic processes. They explain processing relative to databases of knowledge and belief-that is, content. A specific example is syllogistic reasoning, which raises issues of experimenters' interpretations of subjects' reasoning. Science, especially since the advent of understandings of computation, does not have to be reductive. How does this approach transfer onto anthropological topics? Recent cognitive science approaches to anthropological topics have taken a reductive stance in terms of modules. We end with some speculations about a different cognitive approach to, for example, religion. Copyright © 2012 Cognitive Science Society, Inc.

Common Elements in Rare Kidney Diseases: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

PubMed

Aymé, Ségolène; Bockenhauer, Detlef; Day, Simon; Devuyst, Olivier; Guay-Woodford, Lisa M; Ingelfinger, Julie R; Klein, Jon B; Knoers, Nine V A M; Perrone, Ronald D; Roberts, Julia; Schaefer, Franz; Torres, Vicente E; Cheung, Michael; Wheeler, David C; Winkelmayer, Wolfgang C

2017-10-01

Rare kidney diseases encompass at least 150 different conditions, most of which are inherited. Although individual rare kidney diseases raise specific issues, as a group these rare diseases can have overlapping challenges in diagnosis and treatment. These challenges include small numbers of affected patients, unidentified causes of disease, lack of biomarkers for monitoring disease progression, and need for complex care. To address common clinical and patient issues among rare kidney diseases, the KDIGO Controversies Conference entitled, Common Elements in Rare Kidney Diseases, brought together a panel of multidisciplinary clinical providers and patient advocates to address five central issues for rare kidney diseases. These issues encompassed diagnostic challenges, management of kidney functional decline and progression of chronic kidney disease, challenges in clinical study design, translation of advances in research to clinical care, and provision of practical and integrated patient support. Thus, by a process of consensus, guidance for addressing these challenges was developed and is presented here. Copyright © 2017 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

Transitioning issues in adolescent to young adult hemophilia patients with inhibitors: an approach for a growing population.

PubMed

Young, Guy

2010-09-01

The major adverse effect of factor replacement therapy in patients with hemophilia is the development of neutralizing antibodies termed inhibitors. This complication renders standard factor replacement therapy ineffective resulting in increased morbidity and mortality. Until recently, the population of adults with inhibitors was relatively small due to the death of many of the patients from HIV that they contracted from contaminated factor in the early 1980s. With the advent of factor products with reduced risks for deadly infections in the mid-1980s to early 1990s, a cohort of inhibitor patients is now beginning to enter adulthood thus raising the issues regarding the transition of these patients into adulthood. It is, therefore, expected that adult hematologists will be seeing more inhibitor patients and that pediatric hematologists will be faced with managing this transition process, which may not necessarily include transition to an adult facility or adult hematologist. This review will discuss the various issues ranging from choice of medical provider to a discussion of psychosocial and financial issues facing this specific patient population.

Experimentation and evaluation of advanced integrated system concepts

NASA Astrophysics Data System (ADS)

Ross, M.; Garrigus, K.; Gottschalck, J.; Rinearson, L.; Longee, E.

1980-09-01

This final report examines the implementation of a time-phased test bed for experimentation and evaluation of advanced system concepts relative to the future Defense Switched Network (DSN). After identifying issues pertinent to the DSN, a set of experiments which address these issues are developed. Experiments are ordered based on their immediacy and relative importance to DSN development. The set of experiments thus defined allows requirements for a time phased implementation of a test bed to be identified, and several generic test bed architectures which meet these requirements are examined. Specific architecture implementations are costed and cost/schedule profiles are generated as a function of experimental capability. The final recommended system consists of two separate test beds: a circuit switch test bed, configured around an off-the-shelf commercial switch, and directed toward the examination of nearer term and transitional issues raised by the evolving DSN; and a packet/hybrid test bed, featuring a discrete buildup of new hardware and software modules, and directed toward examination of the more advanced integrated voice and data telecommunications issues and concepts.

76 FR 35619 - Labeling and Effectiveness Testing; Sunscreen Drug Products for Over-the-Counter Human Use

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-17

...The Food and Drug Administration (FDA) is issuing this document to address labeling and effectiveness testing for certain over-the counter (OTC) sunscreen products containing specified active ingredients and marketed without approved applications. This document addresses labeling and effectiveness testing issues raised by the nearly 2,900 submissions that we received in response to the sunscreen proposed rule of August 27, 2007 (2007 proposed rule). The document also identifies specific claims that render a product that is subject to this rule misbranded or would not be allowed on any OTC sunscreen product marketed without an approved application. The document does not address issues related to sunscreen active ingredients or certain other issues regarding the GRASE determination for sunscreen products. The document requires OTC sunscreen products to comply with the content and format requirements for OTC drug labeling contained in the 1999 Drug Facts final rule (published in the Federal Register of March 17, 1999, by lifting the delay of implementation date for that rule that we published on September 3, 2004).

75 FR 58449 - Postal Rates

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-24

... discount design. The proceeding will allow certain issues raised in an earlier proceeding to be fully... important threshold legal and policy issues underlying the design of workshare discounts. The Commission... Mail that is CASS-certified and bears an Intelligent Mail barcode. All of these issues are eligible for...

Ethics and Epistemology in Big Data Research.

PubMed

Lipworth, Wendy; Mason, Paul H; Kerridge, Ian; Ioannidis, John P A

2017-12-01

Biomedical innovation and translation are increasingly emphasizing research using "big data." The hope is that big data methods will both speed up research and make its results more applicable to "real-world" patients and health services. While big data research has been embraced by scientists, politicians, industry, and the public, numerous ethical, organizational, and technical/methodological concerns have also been raised. With respect to technical and methodological concerns, there is a view that these will be resolved through sophisticated information technologies, predictive algorithms, and data analysis techniques. While such advances will likely go some way towards resolving technical and methodological issues, we believe that the epistemological issues raised by big data research have important ethical implications and raise questions about the very possibility of big data research achieving its goals.

Evaluation of an expert system for fault detection, isolation, and recovery in the manned maneuvering unit

NASA Technical Reports Server (NTRS)

Rushby, John; Crow, Judith

1990-01-01

The authors explore issues in the specification, verification, and validation of artificial intelligence (AI) based software, using a prototype fault detection, isolation and recovery (FDIR) system for the Manned Maneuvering Unit (MMU). They use this system as a vehicle for exploring issues in the semantics of C-Language Integrated Production System (CLIPS)-style rule-based languages, the verification of properties relating to safety and reliability, and the static and dynamic analysis of knowledge based systems. This analysis reveals errors and shortcomings in the MMU FDIR system and raises a number of issues concerning software engineering in CLIPs. The authors came to realize that the MMU FDIR system does not conform to conventional definitions of AI software, despite the fact that it was intended and indeed presented as an AI system. The authors discuss this apparent disparity and related questions such as the role of AI techniques in space and aircraft operations and the suitability of CLIPS for critical applications.

Ethical Issues in Stem Cell Research

PubMed Central

Lo, Bernard; Parham, Lindsay

2009-01-01

Stem cell research offers great promise for understanding basic mechanisms of human development and differentiation, as well as the hope for new treatments for diseases such as diabetes, spinal cord injury, Parkinson’s disease, and myocardial infarction. However, human stem cell (hSC) research also raises sharp ethical and political controversies. The derivation of pluripotent stem cell lines from oocytes and embryos is fraught with disputes about the onset of human personhood. The reprogramming of somatic cells to produce induced pluripotent stem cells avoids the ethical problems specific to embryonic stem cell research. In any hSC research, however, difficult dilemmas arise regarding sensitive downstream research, consent to donate materials for hSC research, early clinical trials of hSC therapies, and oversight of hSC research. These ethical and policy issues need to be discussed along with scientific challenges to ensure that stem cell research is carried out in an ethically appropriate manner. This article provides a critical analysis of these issues and how they are addressed in current policies. PMID:19366754

When the value of gold is zero.

PubMed

Chase, J Geoffrey; Moeller, Knut; Shaw, Geoffrey M; Schranz, Christoph; Chiew, Yeong Shiong; Desaive, Thomas

2014-06-27

This manuscript presents the concerns around the increasingly common problem of not having readily available or useful "gold standard" measurements. This issue is particularly important in critical care where many measurements used in decision making are surrogates of what we would truly wish to use. However, the question is broad, important and applicable in many other areas.In particular, a gold standard measurement often exists, but is not clinically (or ethically in some cases) feasible. The question is how does one even begin to develop new measurements or surrogates if one has no gold standard to compare with?We raise this issue concisely with a specific example from mechanical ventilation, a core bread and butter therapy in critical care that is also a leading cause of length of stay and cost of care. Our proposed solution centers around a hierarchical validation approach that we believe would ameliorate ethics issues around radiation exposure that make current gold standard measures clinically infeasible, and thus provide a pathway to create a (new) gold standard.

[How to write high-quality epidemiological research paper Ⅵ. Strengthening the Reporting of Observational Studies in Epidemiology-Nutritional Epidemiology (STROBE-nut)].

PubMed

Ding, C Y; Cao, Y; Yang, C; Sun, F; Zhan, S Y

2017-01-10

Concerns have been raised about the reporting quality in nutritional epidemiology. Therefore, strengthening the reporting of observational studies in epidemiology-nutritional epidemiology (STROBE-nut) has been proposed by extending the STROBE statement to include additional recommendations on issues related to nutritional epidemiology and dietary assessment, aiming to provide more specific guidelines on how to report observational research in the field. This paper presents a brief introduction to STROBE-nut and also an explanation of the key points in the additional items, with an example illustrating the application of the checklist.

The role of fearless dominance in differentiating psychopathy from antisocial personality disorder: comment on Marcus, Fulton, and Edens.

PubMed

Patrick, Christopher J; Venables, Noah C; Drislane, Laura E

2013-01-01

Comments on the original article by Marcus et al. (see record 2011-23134-001). Based on their meta-analytic review of the correlates of the two factors of the Psychopathic Personality Inventory (PPI), Fearless Dominance (FD) and Self-Centered Impulsivity (SCI), Marcus, Fulton, and Edens (this issue, pp. 70-79) raise important questions about the role of FD in diagnostic conceptualizations of psychopathy. In considering their findings, general limitations of metaanalyses (e.g., Ioannidis & Lau, 1999) should be borne in mind, along with specific limitations of their analysis. These limitations are discussed here.

PML Nuclear Bodies

PubMed Central

Lallemand-Breitenbach, Valérie; de Thé, Hugues

2010-01-01

PML nuclear bodies are matrix-associated domains that recruit an astonishing variety of seemingly unrelated proteins. Since their discovery in the early 1960s, PML bodies have fascinated cell biologists because of their beauty and their tight association with cellular disorders. The identification of PML, a gene involved in an oncogenic chromosomal translocation, as the key organizer of these domains drew instant interest onto them. The multiple levels of PML body regulation by a specific posttranslational modification, sumoylation, have raised several unsolved issues. Functionally, PML bodies may sequester, modify or degrade partner proteins, but in many ways, PML bodies still constitute an enigma. PMID:20452955

Teaching social determinants of child health in a pediatric advocacy rotation: small intervention, big impact.

PubMed

Klein, Melissa; Vaughn, Lisa M

2010-01-01

Traditionally, medical education does not specifically address the social determinants of health or how to advocate for families' cultural, social or economic needs in spite of our increasingly diverse society. This article describes a new social-legal curriculum added to a Pediatric Resident's Advocacy course. Pediatric interns completed 'Memos To Myself' after the Advocacy rotation. The curriculum impacted residents' (1) realization regarding family circumstances; (2) reflections regarding self and personal practice; and (3) knowledge about advocacy issues and community partnerships for solutions. This curriculum raised awareness about topics that are traditionally not covered in medical education.

A note on the microeconomics of migration.

PubMed

Stahl, K

1983-11-01

"The purpose of this note is to demonstrate in a simple model that an individual's migration from a small town to a large city may be rationalized purely by a consumption motive, rather than the motive of obtaining a higher income. More specifically, it is shown that in a large city an individual may derive a higher utility from spending a given amount of income than in a small town." A formal model is first developed that includes the principal forces at work and is then illustrated using a graphic example. The theoretical and empirical issues raised are considered in the concluding section. excerpt

A phase code for memory could arise from circuit mechanisms in entorhinal cortex

PubMed Central

Hasselmo, Michael E.; Brandon, Mark P.; Yoshida, Motoharu; Giocomo, Lisa M.; Heys, James G.; Fransen, Erik; Newman, Ehren L.; Zilli, Eric A.

2009-01-01

Neurophysiological data reveals intrinsic cellular properties that suggest how entorhinal cortical neurons could code memory by the phase of their firing. Potential cellular mechanisms for this phase coding in models of entorhinal function are reviewed. This mechanism for phase coding provides a substrate for modeling the responses of entorhinal grid cells, as well as the replay of neural spiking activity during waking and sleep. Efforts to implement these abstract models in more detailed biophysical compartmental simulations raise specific issues that could be addressed in larger scale population models incorporating mechanisms of inhibition. PMID:19656654

PML nuclear bodies.

PubMed

Lallemand-Breitenbach, Valérie; de Thé, Hugues

2010-05-01

PML nuclear bodies are matrix-associated domains that recruit an astonishing variety of seemingly unrelated proteins. Since their discovery in the early 1960s, PML bodies have fascinated cell biologists because of their beauty and their tight association with cellular disorders. The identification of PML, a gene involved in an oncogenic chromosomal translocation, as the key organizer of these domains drew instant interest onto them. The multiple levels of PML body regulation by a specific posttranslational modification, sumoylation, have raised several unsolved issues. Functionally, PML bodies may sequester, modify or degrade partner proteins, but in many ways, PML bodies still constitute an enigma.

Concept Innateness, Concept Continuity, and Bootstrapping

PubMed Central

Carey, Susan

2011-01-01

The commentators raised issues relevant to all three important theses of The Origin of Concepts (TOOC). Some questioned the very existence of innate representational primitives, and others questioned my claims about their richness and whether they should be thought of as concepts. Some questioned the existence of conceptual discontinuity in the course of knowledge acquisition and others argued that discontinuity is much more common than portrayed in TOOC. Some raised issues with my characterization of Quinian bootstrapping, and others questioned the dual factor theory of concepts motivated by my picture of conceptual development. PMID:23264705

Informed consent in the context of pharmacogenomic research: ethical considerations.

PubMed

Howard, H C; Joly, Y; Avard, D; Laplante, N; Phillips, M; Tardif, J C

2011-06-01

Although the scientific research surrounding pharmacogenomics (PGx) has been relatively plentiful, the ethical research concerning this discipline has developed rather conservatively. Following investigation of the ethical, legal and social issues (ELSI) of PGx research, as well as consulting with key stakeholders, we identified six outstanding ethical issues raised by the informed consent process in PGx research: (1) scope of consent; (2) consent to 'add-on' studies; (3) protection of personal information; (4) commercialization; (5) data sharing; and (6) potential risks stemming from population-based research. In discussing these six areas as well as offering specific considerations, this article offers a solid base from which future practical guidelines for informed consent in PGx research can be constructed. As such, this effort works toward filling the ELSI gap and provides ethical support to the numerous PGx projects undertaken by researchers every year.

'New embryos' - new challenges for the ethics of stem cell research.

PubMed

Holm, Søren

2008-01-01

Among the many ethical issues raised by human embryonic stem cell research (in the following all references to 'stem cells' should be read as references to human embryonic stem cells), two have gained specific prominence: (1) whether stem cell research is ethically problematic because it entails the destruction of human embryos and (2) what kind of control embryo donors should have over the stem cell lines derived from their embryos. In the present paper, I will analyse how these two issues are engaged by various attempts to derive stem cells from anomalous embryos (e.g. embryos in cleavage arrest, embryos not implanted following pre-implantation genetic diagnosis or embryos created by altered nuclear transfer) or in ways that are claimed to be non-destructive for the embryo (e.g. blastocyst or blastomere biopsy). Copyright 2008 S. Karger AG, Basel.

Ethical Issues in Online Education

ERIC Educational Resources Information Center

Anderson, Bill; Simpson, Mary

2007-01-01

Teaching at a distance raises ethical issues particular to the distance context. When distance teaching is also online teaching, the situation is even more complex. Online teaching environments amplify the ethical issues faced by instructors and students. Online sites support complex discourses and multiple relationships; they cross physical,…

Higher Education in TAFE: An Issues Paper

ERIC Educational Resources Information Center

Moodie, Gavin; Wheelahan, Leesa; Billett, Stephen; Kelly, Ann

2009-01-01

Growth in mixed-sector institutions offering both vocational and higher education qualifications is expected to increase given recent and predicted policy changes. This issues paper focuses on the provision and management of higher education in technical and further education (TAFE) institutes. Issues raised for discussion include the governance…

Sexual Harassment as an Ethical Issue in Academic Life. Issues in Academic Ethics.

ERIC Educational Resources Information Center

Francis, Leslie Pickering

This book provides a full examination of sexual harassment as an ethical issue in education. It considers issues raised by the definition, understanding, and regulation of campus sexual harassment and addresses the arguments that regulation may conflict with academic freedom and choice in relationships. Part 1 contains these chapters: (1) "Sexual…

Perspectives: Using Historical Documents To Think about NIF Issues.

ERIC Educational Resources Information Center

National Archives and Records Service (GSA), Washington, DC.

The purpose of using historical documents in the classroom is to generate and enhance discussion by providing a historical perspective for issues. Five documents are included in this packet and are to be used as a supplemental material for the National Issues Forum (NIF) topics. Issues raised include (1) an analysis of the documents and (2)…

Adding It Up.

ERIC Educational Resources Information Center

Bornstein, Rita

1989-01-01

A survey of institutions conducting or having completed fund-raising campaigns with goals over $1 million confirmed that campaigns have different purposes and structures, and do not all include the same sources and purposes of support in their reports. Fund-raising professionals should consider the issue of consistency in campaign accounting. (MSE)

An investigation of issues related to raising the rural interstate speed limit in Virginia.

DOT National Transportation Integrated Search

1988-01-01

In April of 1987, Congress passed the Surface Transportation and Uniform Relocation Assistance Act of 1987, which allows the states to raise, without penalty, the speed limit on interstate highways outside of urbanized areas with a population of 50,0...

Rehabilitation Broadcasts to Rural Villages. [Draft].

ERIC Educational Resources Information Center

Miles, M.

The scripts are intended for broadcasting in translation to villages in Pakistan to raise awareness about disabilities and to provide practical advice to parents of disabled children. The initial broadcast emphasizes the essential humanity of all disabled persons, while subsequent broadcasts address issues in raising children with mental…

The spectrum of ethical issues in a Learning Health Care System: a systematic qualitative review.

PubMed

McLennan, Stuart; Kahrass, Hannes; Wieschowski, Susanne; Strech, Daniel; Langhof, Holger

2018-04-01

To determine systematically the spectrum of ethical issues that is raised for stakeholders in a 'Learning Health Care System' (LHCS). The systematic review was conducted in PubMed and Google Books between the years 2007 and 2015. The literature search retrieved 1258 publications. Each publication was independently screened by two reviewers for eligibility for inclusion. Ethical issues were defined as arising when a relevant normative principle is not adequately considered or two principles come into conflict. A total of 65 publications were included in the final analysis and were analysed using an adapted version of qualitative content analysis. A coding frame was developed inductively from the data, only the highest-level categories were generated deductively for a life-cycle perspective. A total of 67 distinct ethical issues could be categorized under different phases of the LHCS life-cycle. An overarching theme that was repeatedly raised was the conflict between the current regulatory system and learning health care. The implementation of a LHCS can help realize the ethical imperative to continuously improve the quality of health care. However, the implementation of a LHCS can also raise a number of important ethical issues itself. This review highlights the importance for health care leaders and policy makers to balance the need to protect and respect individual participants involved in learning health care activities with the social value of improving health care.

The Space Shuttle Disaster: Ethical Issues in Organizational Decision-Making.

ERIC Educational Resources Information Center

Kramer, Ronald C.; Jaksa, James A.

Arguing that the issue of organizational decision making and bureaucratic responsibility in the use of technologies with potential for creating social harm should concern everyone, this paper explores the ethical issues raised by organizational decisions concerning the launch of the space shuttle "Challenger." The paper first describes a…

Self-Advocacy. Feature Issue.

ERIC Educational Resources Information Center

Hayden, Mary F., Ed.; Ward, Nancy, Ed.

1994-01-01

This feature issue newsletter looks at issues the self-advocacy movement is raising and the contributions it is making to the lives of people with developmental disabilities. Articles by self-advocates and advisors to self-advocacy organizations talk about their self-advocacy experiences, barriers to self-advocacy, and ways to support it. Primary…

Trustee Quarterly, 1990 (Four Issues).

ERIC Educational Resources Information Center

Trustee Quarterly, 1990

1990-01-01

This document consists of the four issues of the "Trustee Quarterly" for 1990. This series covers topics of current concern to community college trustees. The winter 1990 issue contains articles examining the pros and cons of board standing committees, the role of boards in planning and institutional effectiveness, innovative fund raising in…

Group Counseling in the Schools: Considerations for Child and Family Issues

ERIC Educational Resources Information Center

Crespi, Tony D.; Gustafson, Amy L.; Borges, Silvia M.

2006-01-01

School psychologists are increasingly being confronted with a wide spectrum of psychological, psychosocial, familial, and home-school issues impacting child development. With one in six children raised in alcoholic families, with divorce impacting approximately 60% of families, and with such issues as teenage pregnancy, parental neglect, as well…

Gifted Children and Divorce

ERIC Educational Resources Information Center

Dudley, John; Karnes, Frances A.

2011-01-01

Divorce is often a contentious process with multiple issues to decide, especially in cases in which there are children involved. Divorce raises several legal issues when considering the well-being of children, including those who are gifted. In this article, the authors discuss these issues which include school choice, child support, and custody…

One small edit for humans, one giant edit for humankind? Points and questions to consider for a responsible way forward for gene editing in humans.

PubMed

Howard, Heidi C; van El, Carla G; Forzano, Francesca; Radojkovic, Dragica; Rial-Sebbag, Emmanuelle; de Wert, Guido; Borry, Pascal; Cornel, Martina C

2018-01-01

Gene editing, which allows for specific location(s) in the genome to be targeted and altered by deleting, adding or substituting nucleotides, is currently the subject of important academic and policy discussions. With the advent of efficient tools, such as CRISPR-Cas9, the plausibility of using gene editing safely in humans for either somatic or germ line gene editing is being considered seriously. Beyond safety issues, somatic gene editing in humans does raise ethical, legal and social issues (ELSI), however, it is suggested to be less challenging to existing ethical and legal frameworks; indeed somatic gene editing is already applied in (pre-) clinical trials. In contrast, the notion of altering the germ line or embryo such that alterations could be heritable in humans raises a large number of ELSI; it is currently debated whether it should even be allowed in the context of basic research. Even greater ELSI debates address the potential use of germ line or embryo gene editing for clinical purposes, which, at the moment is not being conducted and is prohibited in several jurisdictions. In the context of these ongoing debates surrounding gene editing, we present herein guidance to further discussion and investigation by highlighting three crucial areas that merit the most attention, time and resources at this stage in the responsible development and use of gene editing technologies: (1) conducting careful scientific research and disseminating results to build a solid evidence base; (2) conducting ethical, legal and social issues research; and (3) conducting meaningful stakeholder engagement, education and dialogue.

Environmental Awareness: Relating Current Issues to Biology.

ERIC Educational Resources Information Center

DeFina, Anthony

1995-01-01

Presents examples of incorporating environmental issues into lesson plans to raise the level of students' environmental awareness. Topics include: ecology, taxonomy, biochemistry, energy reactions, cell structure and function, genetics and development, and human biology. (JRH)

Nora's Voice.

ERIC Educational Resources Information Center

Rameka, Nora; Stalker, Joyce

1996-01-01

The cultural and gender issues raised by a Maori adult educator (Nora Rameka) are framed by the interviewer (Joyce Stalker) who comments on methodological difficulties and compromises that were necessary in order to have Maori perspectives represented in this issue. (SK)

Exploring New Challenges of High-Resolution SWOT Satellite Altimetry with a Regional Model of the Solomon Sea

NASA Astrophysics Data System (ADS)

Brasseur, P.; Verron, J. A.; Djath, B.; Duran, M.; Gaultier, L.; Gourdeau, L.; Melet, A.; Molines, J. M.; Ubelmann, C.

2014-12-01

The upcoming high-resolution SWOT altimetry satellite will provide an unprecedented description of the ocean dynamic topography for studying sub- and meso-scale processes in the ocean. But there is still much uncertainty on the signal that will be observed. There are many scientific questions that are unresolved about the observability of altimetry at vhigh resolution and on the dynamical role of the ocean meso- and submesoscales. In addition, SWOT data will raise specific problems due to the size of the data flows. These issues will probably impact the data assimilation approaches for future scientific or operational oceanography applications. In this work, we propose to use a high-resolution numerical model of the Western Pacific Solomon Sea as a regional laboratory to explore such observability and dynamical issues, as well as new data assimilation challenges raised by SWOT. The Solomon Sea connects subtropical water masses to the equatorial ones through the low latitude western boundary currents and could potentially modulate the tropical Pacific climate. In the South Western Pacific, the Solomon Sea exhibits very intense eddy kinetic energy levels, while relatively little is known about the mesoscale and submesoscale activities in this region. The complex bathymetry of the region, complicated by the presence of narrow straits and numerous islands, raises specific challenges. So far, a Solomon sea model configuration has been set up at 1/36° resolution. Numerical simulations have been performed to explore the meso- and submesoscales dynamics. The numerical solutions which have been validated against available in situ data, show the development of small scale features, eddies, fronts and filaments. Spectral analysis reveals a behavior that is consistent with the SQG theory. There is a clear evidence of energy cascade from the small scales including the submesoscales, although those submesoscales are only partially resolved by the model. In parallel, investigations have been conducted using image assimilation approaches in order to explore the richness of high-resolution altimetry missions. These investigations illustrate the potential benefit of combining tracer fields (SST, SSS and spiciness) with high-resolution SWOT data to estimate the fine-scale circulation.

Coping with Dialectical Tensions.

ERIC Educational Resources Information Center

Brockriede, Wayne

This paper discusses some of the central issues involved in philosophizing about rhetoric by raising two primary questions within the context of three traditional branches of philosophy: ontology, axiology, and epistemology. The two questions raised are: What are dialectical tensions in a philosophy of rhetoric? and How does a person try to cope…

Dialog: Should Faculty Merit Raises Be Linked to Enrollment Increases?

ERIC Educational Resources Information Center

Change, 1978

1978-01-01

The issue of linking faculty merit raises to enrollment increases (and therefore to student recruitment) is addressed by Mary-Anne Vetterling of Northeastern University, William E. Spellman of Coe College, Suzanne E. Lindenau of the University of Georgia, and James J. Bess of Teachers College. (LBH)

A Hands-On Activity to Raise Awareness about Healthy Sun Exposure

ERIC Educational Resources Information Center

João Fonseca, Maria; Costa, Patrício; Lencastre, Leonor; Tavares, Fernando

2015-01-01

Excessive exposure to solar ultraviolet (UV) radiation causes sunburn and has been consistently associated with increased susceptibility to melanoma and skin ageing. Acknowledging the need to promote healthy sun exposure habits, numerous educational initiatives have been developed to raise public awareness towards this issue. However, studies…

Institutional Responses to the Quality/Quantity Issue in Teacher Training.

ERIC Educational Resources Information Center

Schlechty, Phillip C.; Vance, Victor S.

1983-01-01

This North Carolina-based study argues that a reexamination is needed of the competitive position of teaching in the larger occupational structure of society and that the quality of the teaching force will not be raised merely by raising entrance or exit standards in teacher education. (JBM)

Cultural Barriers to Change in Assessment Practices in Higher Education

ERIC Educational Resources Information Center

Jenkins, Deborah Bainer

2007-01-01

The culture at the authors' institution raised barriers to changing from traditional assessment to portfolio assessment in the doctoral program. A Culture of Independence presented barriers of time and functional inadequacy. A Culture of Compliance raised trust, group process, and membership issues. These barriers were managed and overcome using…

Ethical and Logistical Issues Raised by the Advanced Donation Program "Pay It Forward" Scheme.

PubMed

Ross, Lainie Friedman; Rodrigue, James R; Veatch, Robert M

2017-10-01

The advanced donation program was proposed in 2014 to allow an individual to donate a kidney in order to provide a voucher for a kidney in the future for a particular loved one. In this article, we explore the logistical and ethical issues that such a program raises. We argue that such a program is ethical in principle but there are many logistical issues that need to be addressed to ensure that the actual program is fair to both those who do and do not participate in this program. © The Author 2017. Published by Oxford University Press, on behalf of the Journal of Medicine and Philosophy Inc. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Magnetic Nozzle and Plasma Detachment Experiment

NASA Technical Reports Server (NTRS)

Chavers, Gregory; Dobson, Chris; Jones, Jonathan; Martin, Adam; Bengtson, Roger D.; Briezman, Boris; Arefiev, Alexey; Cassibry, Jason; Shuttpelz, Branwen; Deline, Christopher

2006-01-01

High power plasma propulsion can move large payloads for orbit transfer (such as the ISS), lunar missions, and beyond with large savings in fuel consumption owing to the high specific impulse. At high power, lifetime of the thruster becomes an issue. Electrodeless devices with magnetically guided plasma offer the advantage of long life since magnetic fields confine the plasma radially and keep it from impacting the material surfaces. For decades, concerns have been raised about the plasma remaining attached to the magnetic field and returning to the vehicle along the closed magnetic field lines. Recent analysis suggests that this may not be an issue of the magnetic field is properly shaped in the nozzle region and the plasma has sufficient energy density to stretch the magnetic field downstream. An experiment was performed to test the theory regarding the Magneto-hydrodynamic (MHD) detachment scenario. Data from this experiment will be presented. The Variable Specific Impulse Magnetoplasma Rocket (VASIMR) being developed by the Ad Astra Rocket Company uses a magnetic nozzle as described above. The VASIMR is also a leading candidate for exploiting an electric propulsion test platform being considered for the ISS.

Empathy, social media, and directed altruistic living organ donation.

PubMed

Moorlock, Greg; Draper, Heather

2018-06-01

In this article we explore some of the ethical dimensions of using social media to increase the number of living kidney donors. Social media provides a platform for changing non-identifiable 'statistical victims' into 'real people' with whom we can identify and feel empathy: the so-called 'identifiable victim effect', which prompts charitable action. We examine three approaches to promoting kidney donation using social media which could take advantages of the identifiable victim effect: (a) institutionally organized campaigns based on historical cases aimed at promoting non-directed altruistic donation; (b) personal case-based campaigns organized by individuals aimed at promoting themselves/or someone with whom they are in a relationship as a recipient of directed donation; (c) institutionally organized personal case-based campaigns aimed at promoting specific recipients for directed donation. We will highlight the key ethical issues raised by these approaches, and will argue that the third option, despite raising ethical concerns, is preferable to the other two. © 2018 The Authors Bioethics Published by John Wiley & Sons Ltd.

Psychiatric research: what ethical concerns do LRECs encounter? A postal survey. Local research ethics committees.

PubMed

Osborn, D P J; Fulford, K W M

2003-02-01

Psychiatric research can occasionally present particular ethical dilemmas, but it is not clear what kind of problems local research ethics committees (LRECs) actually experience in this field. We aimed to assess the type of problems that committees encounter with psychiatric research, using a postal survey of 211 LRECs. One hundred and seven (51%) of those written to replied within the time limit. Twenty eight (26%) experienced few problems with psychiatric applications. Twenty six (24%) emphasised the value of a psychiatric expert on the committee. The most common issues raised were informed consent (n=64, 60%) and confidentiality (n=17, 16%). The use of placebos (and washout periods) (n=18, 17%), the validity of psychiatric questionnaires (n=16, 15%) and overuse of psychiatric "jargon" (n=14, 13%) in psychiatric applications also raised concern. Our results suggest that LRECs have specific concerns regarding methodology, consent, and confidentiality in psychiatric research, and that they find psychiatric input invaluable.

[Aesthetic medicine and aspects related to liability, medical professional and social law].

PubMed

Jansen, Christoph

2006-01-01

There are no special legal arrangements for the field of aesthetic medicine; rather, the general medico-legal regulations apply although they raise specific questions as far as aesthetic medicine is concerned. Legally, a contract exists between physician and patient which is also applicable to aesthetic medicine. This means that the physician owes the patient only the provision of a proper, non-defective service, but does not need to guarantee that it actually leads to the desired outcome. Before performing a medically non-indicated procedure the physician is obliged to provide the patient with particularly thorough information about this procedure. Various problems and issues are raised by the advertising limitations for medical professionals and the maintenance of the boundaries confining the special field of aesthetic medicine. Medically indicated procedures are suitable for statutory reimbursement if the patient suffers from "physical disfigurement" or somatic complaints that lead to considerable impairment and if there are no other, cheaper treatment options available.

Predicting Fluid Responsiveness by Passive Leg Raising: A Systematic Review and Meta-Analysis of 23 Clinical Trials.

PubMed

Cherpanath, Thomas G V; Hirsch, Alexander; Geerts, Bart F; Lagrand, Wim K; Leeflang, Mariska M; Schultz, Marcus J; Groeneveld, A B Johan

2016-05-01

Passive leg raising creates a reversible increase in venous return allowing for the prediction of fluid responsiveness. However, the amount of venous return may vary in various clinical settings potentially affecting the diagnostic performance of passive leg raising. Therefore we performed a systematic meta-analysis determining the diagnostic performance of passive leg raising in different clinical settings with exploration of patient characteristics, measurement techniques, and outcome variables. PubMed, EMBASE, the Cochrane Database of Systematic Reviews, and citation tracking of relevant articles. Clinical trials were selected when passive leg raising was performed in combination with a fluid challenge as gold standard to define fluid responders and non-responders. Trials were included if data were reported allowing the extraction of sensitivity, specificity, and area under the receiver operating characteristic curve. Twenty-three studies with a total of 1,013 patients and 1,034 fluid challenges were included. The analysis demonstrated a pooled sensitivity of 86% (95% CI, 79-92), pooled specificity of 92% (95% CI, 88-96), and a summary area under the receiver operating characteristic curve of 0.95 (95% CI, 0.92-0.98). Mode of ventilation, type of fluid used, passive leg raising starting position, and measurement technique did not affect the diagnostic performance of passive leg raising. The use of changes in pulse pressure on passive leg raising showed a lower diagnostic performance when compared with passive leg raising-induced changes in flow variables, such as cardiac output or its direct derivatives (sensitivity of 58% [95% CI, 44-70] and specificity of 83% [95% CI, 68-92] vs sensitivity of 85% [95% CI, 78-90] and specificity of 92% [95% CI, 87-94], respectively; p < 0.001). Passive leg raising retains a high diagnostic performance in various clinical settings and patient groups. The predictive value of a change in pulse pressure on passive leg raising is inferior to a passive leg raising-induced change in a flow variable.

"It's Still Science but Not Like Normal Science": Girls' Responses to the Teaching of Socio-Scientific Issues

ERIC Educational Resources Information Center

Morris, Helen

2014-01-01

Socio-scientific issues, which are often controversial, involve the use of science and are of interest to society, raising ethical and moral dilemmas. Examples of these issues could include genetic technology or air pollution. Following a curriculum reform in England in 2006, socioscientific issues now have a heightened presence in the 14-16…

Ethical issues when using social media for health outside professional relationships.

PubMed

DeCamp, Matthew

2015-04-01

Social media have the potential to revolutionize health and healthcare, but fulfilling this potential requires attention to the ethical issues social media may raise. This article reviews the major ethical issues arising when social media are used for research, public health, mobile health applications, and global health. It focuses on social media use outside fiduciary relationships between healthcare professionals and patients. Emphasis is given to the potential of social media in these contexts, the ethical issues relatively unique to each, and where possible how existing ethical principles and frameworks could help navigate these issues. In some cases social media create the circumstance for particular ethical issues but also facilitate managing them, such as in informed consent for research. In other cases, disagreement exists about whether social media - despite their potential - should be used for certain purposes, such as in public health surveillance (where confidentiality represents a significant ethical concern). In still others, ethical uncertainty exists about how social media will affect ethical issues, such as inequality in global health. As social media technologies continue to develop, identifying and managing the ethical issues they raise will be critical to their success in improving health while preserving fundamental ethical values.

Financing of health systems to achieve the health Millennium Development Goals in low-income countries.

PubMed

Fryatt, Robert; Mills, Anne; Nordstrom, Anders

2010-01-30

Concern that underfunded and weak health systems are impeding the achievement of the health Millennium Development Goals in low-income countries led to the creation of a High Level Taskforce on Innovative International Financing for Health Systems in September, 2008. This report summarises the key challenges faced by the Taskforce and its Working Groups. Working Group 1 examined the constraints to scaling up and costs. Challenges included: difficulty in generalisation because of scarce and context-specific health-systems knowledge; no consensus for optimum service-delivery approaches, leading to wide cost differences; no consensus for health benefits; difficulty in quantification of likely efficiency gains; and challenges in quantification of the financing gap owing to uncertainties about financial commitments for health. Working Group 2 reviewed the different innovative mechanisms for raising and channelling funds. Challenges included: variable definitions of innovative finance; small evidence base for many innovative finance mechanisms; insufficient experience in harmonisation of global health initiatives; and inadequate experience in use of international investments to improve maternal, newborn, and child health. The various mechanisms reviewed and finally recommended all had different characteristics, some focusing on specific problems and some on raising resources generally. Contentious issues included the potential role of the private sector, the rights-based approach to health, and the move to results-based aid. The challenges and disagreements that arose during the work of the Taskforce draw attention to the many issues facing decision makers in low-income countries. International donors and recipient governments should work together to improve the evidence base for strengthening health systems, increase long-term commitments, and improve accountability through transparent and inclusive national approaches. Copyright 2010 Elsevier Ltd. All rights reserved.

From Cases to Capacity? A Critical Reflection on the Role of ‘Ethical Dilemmas’ in the Development of Dual-Use Governance

PubMed Central

Edwards, Brett; Revill, James; Bezuidenhout, Louise

2016-01-01

The dual-use issue is often framed as a series of paralyzing ‘dilemmas’ facing the scientific community as well as institutions which support innovation. While this conceptualization of the dual-use issue can be useful in certain contexts (such as in awareness-raising and as part of educational activities directed at the scientific community) its usefulness is more limited when reflecting on the governance and politics of the dual-use issue. Within this paper, key shortcomings of the dilemma framing are outlined. It is argued that many of the issues raised in the most recent debates about ‘dual-use’ bird flu research remain unresolved. This includes questions about the trajectories of certain lines of research, as well as broader trends in the practice and governance of science. This leads to difficult questions about current approaches to the dual-use issue within the US, as well as internationally. PMID:23703451

Genetically Engineered Plants and Foods: A Scientist's Analysis of the Issues (Part I).

PubMed

Lemaux, Peggy G

2008-01-01

Through the use of the new tools of genetic engineering, genes can be introduced into the same plant or animal species or into plants or animals that are not sexually compatible-the latter is a distinction with classical breeding. This technology has led to the commercial production of genetically engineered (GE) crops on approximately 250 million acres worldwide. These crops generally are herbicide and pest tolerant, but other GE crops in the pipeline focus on other traits. For some farmers and consumers, planting and eating foods from these crops are acceptable; for others they raise issues related to safety of the foods and the environment. In Part I of this review some general and food issues raised regarding GE crops and foods will be addressed. Responses to these issues, where possible, cite peer-reviewed scientific literature. In Part II to appear in 2009, issues related to environmental and socioeconomic aspects of GE crops and foods will be covered.

Ethical Issues Raised by Private Practice Physiotherapy Are More Diverse than First Meets the Eye: Recommendations from a Literature Review

PubMed Central

Drolet, Marie-Josée; Williams-Jones, Bryn

2015-01-01

ABSTRACT Purpose: Physiotherapy in private practice differs from physiotherapy practised in a public setting in several ways, the most evident of which is the for-profit nature of private physiotherapy clinics; these differences can generate distinct and challenging ethical issues. The objectives of this article are to identify ethical issues encountered by physiotherapists in private practice settings and to identify potential solutions and recommendations to address these issues. Method: After a literature search of eight databases, 39 studies addressing ethical issues in a private practice context were analyzed. Results: A total of 25 ethical issues emerging from the included studies were classified into three main categories: (1) business and economic issues (e.g., conflicts of interests, inequity in a managed care context, lack of time affecting quality of care); (2) professional issues (e.g., professional autonomy, clinical judgment, treatment effectiveness, professional conduct); and (3) patients' rights and welfare issues (e.g., confidentiality, power asymmetries, paternalism vs. patient autonomy, informed consent). Recommendations as to how physiotherapists could better manage these issues were then identified and categorized. Conclusions: The physiotherapy community should reflect on the challenges raised by private practice so that professionals can be supported—through education, research, and good governance—in providing the best possible care for their patients. PMID:25931663

Alcohol on Campus: Three Current Issues.

ERIC Educational Resources Information Center

Fulton, Donald R.; Spooner, Sue E.

1987-01-01

Offers views on three issues important to campus alcohol policy: (1) teaching responsible drinking; (2) operating campus pubs; and (3) raising the legal drinking age. Asserts that carefully considered decisions are needed to help establish normative behavior. (Author/NB)

Ethical Responsibility Key to Computer Security.

ERIC Educational Resources Information Center

Lynn, M. Stuart

1989-01-01

The pervasiveness of powerful computers and computer networks has raised the specter of new forms of abuse and of concomitant ethical issues. Blurred boundaries, hackers, the Computer Worm, ethical issues, and implications for academic institutions are discussed. (MLW)

Implementing risk-stratified screening for common cancers: a review of potential ethical, legal and social issues.

PubMed

Hall, A E; Chowdhury, S; Hallowell, N; Pashayan, N; Dent, T; Pharoah, P; Burton, H

2014-06-01

The identification of common genetic variants associated with common cancers including breast, prostate and ovarian cancers would allow population stratification by genotype to effectively target screening and treatment. As scientific, clinical and economic evidence mounts there will be increasing pressure for risk-stratified screening programmes to be implemented. This paper reviews some of the main ethical, legal and social issues (ELSI) raised by the introduction of genotyping into risk-stratified screening programmes, in terms of Beauchamp and Childress's four principles of biomedical ethics--respect for autonomy, non-maleficence, beneficence and justice. Two alternative approaches to data collection, storage, communication and consent are used to exemplify the ELSI issues that are likely to be raised. Ultimately, the provision of risk-stratified screening using genotyping raises fundamental questions about respective roles of individuals, healthcare providers and the state in organizing or mandating such programmes, and the principles, which underpin their provision, particularly the requirement for distributive justice. The scope and breadth of these issues suggest that ELSI relating to risk-stratified screening will become increasingly important for policy-makers, healthcare professionals and a wide diversity of stakeholders. © The Author 2013. Published by Oxford University Press on behalf of Faculty of Public Health.

Navy Warfare Development Command’s NEXT Magazine, Spring 2014 Edition. Volume 2, Number 1

DTIC Science & Technology

2014-05-01

m~plqy pr«i:ion """apron:. (tlld ~rm barrk> damag" a:sfl:-sm.gnt. (U..S. ,. IQ \\.)’ photo by Kun L0tg{lllkf~IU1«SSN) 14 nEXT SPRING2014 lead <o an...intel6gence windfaJ but may also overwhelm intelligence analysts. The OAW raises some interesting legal issues. For instance, the possibility of...against terrorists has Glready raised concerns at the United Nations about robotic warfare. AI of these issues will need to be addressed as the DAW

Harvard and Money; A Memorandum on Issues and Choices.

ERIC Educational Resources Information Center

Harvard Univ., Cambridge , MA. Univ. Committee on Governance.

This report discusses some of the financial issues and choices with which Harvard University will have to cope in an environment of increased stringency: issues of money-allocation, money raising, and money management. Part I presents highlights of Harvard's recent financial history and its prospects in quantitative terms. Part II presents some…

Higher Education Funding Issues: U.S. / UK Comparison

ERIC Educational Resources Information Center

Orkodashvili, Mariam

2007-01-01

The paper compares and contrasts higher education funding sources and systems in the U.S. and the UK. The issues raised in the paper pertain to the major challenge of academia: finding financial support in times of limited resources and enhanced competition. The issues discussed throughout the paper are: funding and quality assessment of…

Ethical Issues Associated with Information and Communication Technology in Counseling and Guidance

ERIC Educational Resources Information Center

Sampson, James P., Jr.; Makela, Julia Panke

2014-01-01

For more than 50 years, literature on the use of information and communication technology in counseling and guidance has presented ethical issues related to the development and use of technologies in practice. This paper reviews the ethical issues raised, organizing them into three categories: Social equity, resources, and services. Career…

Why Research Design and Methods Is So Crucial to Understanding Drug Use/Abuse: Introduction to the Special Issue.

PubMed

Scheier, Lawrence M

2018-06-01

The collection of articles in this special issue both raise the bar and inspire new thinking with regard to both design and methodology concerns that influence drug use/abuse research. Thematically speaking, the articles focus on issues related to missing data, response formats, strategies for data harmonization, propensity scoring methods as an alternative to randomized control trials, integrative data analysis, statistical corrections to reduce bias from attrition, challenges faced from conducting large-scale evaluations, and employing abductive theory of method as an alternative to the more traditional hypothetico-deductive reasoning. Collectively, these issues are of paramount importance as they provide specific means to improve our investigative tools and refine the logical framework we employ to examine the problem of drug use/abuse. Each of the authors addresses a specific challenge outlining how it affects our current research efforts and then outlines remedies that can advance the field. To their credit, they have included issues that affect both etiology and prevention, thus broadening our horizons as we learn more about developmental processes causally related to drug use/abuse and intervention strategies that can mitigate developmental vulnerability. This is the essential dialogue required to advance our intellectual tool kit and improve the research skills we bring to bear on the important questions facing the field of drug use/abuse. Ultimately, the goal is to increase our ability to identify the causes and consequences of drug use/abuse and find ways to ameliorate these problems as we engage the public health agenda.

77 FR 36231 - Americans With Disabilities Act (ADA) and Architectural Barriers Act (ABA) Accessibility...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-18

... Agency (FEMA) in the aftermath of Hurricanes Katrina and Rita raised issues regarding the application of... limitations. Emergency transportable housing units provided in the aftermath of Hurricanes Katrina and Rita... transportable housing units that were raised in the aftermath of Hurricanes Katrina and Rita. The committee...

Is Your Salary Schedule up to Speed?

ERIC Educational Resources Information Center

Neugebauer, Roger

1994-01-01

Presents four key questions for day-care center administrators to consider when evaluating their salary schedules: (1) what are we paying for?; (2) is our pay equitable?; (3) should we offer annual increases?; and (4) should we offer merit raises? Considers various issues raised by these questions, based upon an analysis of over 100 salary…

Environmental Awareness Raising through Universities--City Authorities' Cooperation

ERIC Educational Resources Information Center

Shelest, Ksenia D.; Ionov, Victor V.; Tikhomirov, Leonid Y.

2017-01-01

Purpose: This paper aims to the environmental awareness raising as a key issue of education for sustainable development. Youth Environmental Volunteers Movement in the area of coastal oil response operations in St. Petersburg is presented in this paper as a successful initiative in the field of environmental awareness through universities and city…

Education for the Creative Cities: Awareness Raising on Urban Challenges and Biocultural Preservation

ERIC Educational Resources Information Center

Mammadova, Aida

2018-01-01

Creative Cities are facing the big challenges due to the demographical, environmental and economic issues. In this study we considered to create the educational fieldworks inside the creative city and raise the awareness in youth about the importance of the biocultural preservations to sustain the city's creativity and sustainability. Our…

Applying bioethical principles to human biomonitoring.

PubMed

Harrison, Myron

2008-06-05

Bioethical principles are widely used as a normative framework in areas of human research and medical care. In recent years there has been increasing formalization of their use in public health decisions. The "traditional bioethical principles" are applied in this discussion to the important issue human biomonitoring for environmental exposures. They are: (1) Autonomy--Also known as the "respect for humans" principle, people understand their own best interests; (2) Beneficence--"do good" for people; (3) Nonmaleficence--"do no harm"; (4) Justice--fair distribution of benefits and costs (including risks to health) across stakeholders.Some of the points made are: (1) There is not a single generic bioethical analysis applicable to the use of human biomonitoring data, each specific use requires a separate deliberation; (2) Using unidentified, population-based biomonitoring information for risk assessment or population surveillance raises fewer bioethical concerns than personally identified biomonitoring information such as employed in health screening; (3) Companies should proactively apply normative bioethical principles when considering the disposition of products and by-products in the environment and humans; (4) There is a need for more engagement by scholars on the bioethical issues raised by the use of biomarkers of exposure; (5) Though our scientific knowledge of biology will continue to increase, there will always be a role for methods or frameworks to resolve substantive disagreements in the meaning of this data that are matters of belief rather than knowledge.

Applying bioethical principles to human biomonitoring

PubMed Central

Harrison, Myron

2008-01-01

Bioethical principles are widely used as a normative framework in areas of human research and medical care. In recent years there has been increasing formalization of their use in public health decisions. The "traditional bioethical principles" are applied in this discussion to the important issue human biomonitoring for environmental exposures. They are: (1) Autonomy – Also known as the "respect for humans" principle, people understand their own best interests; (2) Beneficence – "do good" for people; (3) Nonmaleficence – "do no harm"; (4) Justice – fair distribution of benefits and costs (including risks to health) across stakeholders. Some of the points made are: (1) There is not a single generic bioethical analysis applicable to the use of human biomonitoring data, each specific use requires a separate deliberation; (2) Using unidentified, population-based biomonitoring information for risk assessment or population surveillance raises fewer bioethical concerns than personally identified biomonitoring information such as employed in health screening; (3) Companies should proactively apply normative bioethical principles when considering the disposition of products and by-products in the environment and humans; (4) There is a need for more engagement by scholars on the bioethical issues raised by the use of biomarkers of exposure; (5) Though our scientific knowledge of biology will continue to increase, there will always be a role for methods or frameworks to resolve substantive disagreements in the meaning of this data that are matters of belief rather than knowledge. PMID:18541074

Education and training in psychiatry in the U.K.

PubMed

Carney, Stuart; Bhugra, Dinesh K

2013-07-01

Recent training and education changes have raised important issues in delivery of psychiatric education at all levels. In this article, the authors describe the current status of mental health education in the training of all doctors and postgraduate training and education in psychiatry in the U.K. The authors explore and describe some of the initiatives that are being used in order to increase exposure to mental health placements in the Foundation Program, and they then describe the existing specific mental health opportunities within general practice and other specialist training programs. After graduation from medical school, a two-year Foundation training program is a must, and, at the end of the first year, trainees become eligible for full registration with the "regulator," the General Medical Council; after finishing the second year, they become eligible to undertake specialist training. Psychiatry training takes up to 6 years, and six specialties are recognized as leading to certificates for completion of training before independent practice. These six specialties are 1) general and community; 2) child and adolescent; 3) medical psychotherapy; 4) forensic psychiatry; 5) psychiatry of old age; and 6) psychiatry of learning disability. Also, three subspecialties-liaison psychiatry, addictions, and rehabilitation-form a part of the training in general and community psychiatry. The authors discuss advantages and disadvantages of such an approach and raise key issues related to ongoing work to improve recruitment, progression, and retention of trainee psychiatrists.

Conventional Prompt Global Strike and Long-Range Ballistic Missiles: Background and Issues

DTIC Science & Technology

2013-01-10

and Long-Range Ballistic Missiles Congressional Research Service Forward-Based Global Strike ( FBGS ...they may address the nuclear ambiguity issues raised by long-range ballistic missiles in the CPGS program. Forward-Based Global Strike ( FBGS

76 FR 383 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-04

... interest issues raised by the complaint. FOR FURTHER INFORMATION CONTACT: Marilyn R. Abbott, Secretary to... Commission. Issued: December 28, 2010. Marilyn R. Abbott, Secretary to the Commission. [FR Doc. 2010-33131...

76 FR 4722 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-26

... public interest issues raised by the complaint. FOR FURTHER INFORMATION CONTACT: Marilyn R. Abbott...)(4)). By order of the Commission. Issued: January 21, 2011. Marilyn R. Abbott, Secretary to the...

77 FR 35844 - Safety Zone; Olde Ellison Bay Days Fireworks Display, Ellison Bay, WI

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-15

... of Proposed Rulemaking A. Regulatory History and Information The Coast Guard is issuing this... of any grant or loan recipients, and will not raise any novel legal or policy issues. The safety zone...

42 CFR 422.503 - General provisions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... activities, the furnishing of services, the quality improvement program, and the administrative and... program, including but not limited to reporting potential issues, investigating issues, conducting self... raised, investigating potential compliance problems as identified in the course of self-evaluations and...

The Light Node Communication Framework: A New Way to Communicate Inside Smart Homes.

PubMed

Plantevin, Valère; Bouzouane, Abdenour; Gaboury, Sebastien

2017-10-20

The Internet of things has profoundly changed the way we imagine information science and architecture, and smart homes are an important part of this domain. Created a decade ago, the few existing prototypes use technologies of the day, forcing designers to create centralized and costly architectures that raise some issues concerning reliability, scalability, and ease of access which cannot be tolerated in the context of assistance. In this paper, we briefly introduce a new kind of architecture where the focus is placed on distribution. More specifically, we respond to the first issue we encountered by proposing a lightweight and portable messaging protocol. After running several tests, we observed a maximized bandwidth, whereby no packets were lost and good encryption was obtained. These results tend to prove that our innovation may be employed in a real context of distribution with small entities.

The Light Node Communication Framework: A New Way to Communicate Inside Smart Homes

PubMed Central

Bouzouane, Abdenour; Gaboury, Sebastien

2017-01-01

The Internet of things has profoundly changed the way we imagine information science and architecture, and smart homes are an important part of this domain. Created a decade ago, the few existing prototypes use technologies of the day, forcing designers to create centralized and costly architectures that raise some issues concerning reliability, scalability, and ease of access which cannot be tolerated in the context of assistance. In this paper, we briefly introduce a new kind of architecture where the focus is placed on distribution. More specifically, we respond to the first issue we encountered by proposing a lightweight and portable messaging protocol. After running several tests, we observed a maximized bandwidth, whereby no packets were lost and good encryption was obtained. These results tend to prove that our innovation may be employed in a real context of distribution with small entities. PMID:29053581

Photovoice ethics: perspectives from Flint Photovoice.

PubMed

Wang, C C; Redwood-Jones, Y A

2001-10-01

Photovoice is a participatory health promotion strategy in which people use cameras to document their health and work realities. As participants engage in a group process of critical reflection, they may advocate for change in their communities by using the power of their images and stories to communicate with policy makers. In public health initiatives from China to California, community people have used photovoice to carry out participatory needs assessment, conduct participatory evaluation, and reach policy makers to improve community health. This article begins to address ethical issues raised by the use of photovoice: the potential for invasion of privacy and how that may be prevented; issues in recruitment, representation, participation, and advocacy; and specific methodological techniques that should be used to minimize participants' risks and to maximize benefits. The authors describe lessons learned from the large-scale Flint Photovoice involving youth, adults, and policy makers.

Brain Dynamics: Methodological Issues and Applications in Psychiatric and Neurologic Diseases

NASA Astrophysics Data System (ADS)

Pezard, Laurent

The human brain is a complex dynamical system generating the EEG signal. Numerical methods developed to study complex physical dynamics have been used to characterize EEG since the mid-eighties. This endeavor raised several issues related to the specificity of EEG. Firstly, theoretical and methodological studies should address the major differences between the dynamics of the human brain and physical systems. Secondly, this approach of EEG signal should prove to be relevant for dealing with physiological or clinical problems. A set of studies performed in our group is presented here within the context of these two problematic aspects. After the discussion of methodological drawbacks, we review numerical simulations related to the high dimension and spatial extension of brain dynamics. Experimental studies in neurologic and psychiatric disease are then presented. We conclude that if it is now clear that brain dynamics changes in relation with clinical situations, methodological problems remain largely unsolved.

Banking biological collections: data warehousing, data mining, and data dilemmas in genomics and global health policy.

PubMed

Blatt, R J R

2000-01-01

While DNA databases may offer the opportunity to (1) assess population-based prevalence of specific genes and variants, (2) simplify the search for molecular markers, (3) improve targeted drug discovery and development for disease management, (4) refine strategies for disease prevention, and (5) provide the data necessary for evidence-based decision-making, serious scientific and social questions remain. Whether samples are identified, coded, or anonymous, biological banking raises profound ethical and legal issues pertaining to access, informed consent, privacy and confidentiality of genomic information, civil liberties, patenting, and proprietary rights. This paper provides an overview of key policy issues and questions pertaining to biological banking, with a focus on developments in specimen collection, transnational distribution, and public health and academic-industry research alliances. It highlights the challenges posed by the commercialization of genomics, and proposes the need for harmonization of biological banking policies.

Evaluating "Blair's Educational Legacy?": Some Comments on the Special Issue of "Oxford Review of Education"

ERIC Educational Resources Information Center

Whitty, Geoff

2009-01-01

The December 2008 special issue of the "Oxford Review of Education" provided a review of education policy during Tony Blair's tenure as Prime Minister. This paper forms a response to the ten contributions to that special issue and discusses some of the issues raised in them. While a few positive aspects of education under New Labour were…

Feedback about Teaching in Higher Ed: Neglected Opportunities to Promote Change.

PubMed

Gormally, Cara; Evans, Mara; Brickman, Peggy

2014-01-01

Despite ongoing dissemination of evidence-based teaching strategies, science teaching at the university level is less than reformed. Most college biology instructors could benefit from more sustained support in implementing these strategies. One-time workshops raise awareness of evidence-based practices, but faculty members are more likely to make significant changes in their teaching practices when supported by coaching and feedback. Currently, most instructional feedback occurs via student evaluations, which typically lack specific feedback for improvement and focus on teacher-centered practices, or via drop-in classroom observations and peer evaluation by other instructors, which raise issues for promotion, tenure, and evaluation. The goals of this essay are to summarize the best practices for providing instructional feedback, recommend specific strategies for providing feedback, and suggest areas for further research. Missed opportunities for feedback in teaching are highlighted, and the sharing of instructional expertise is encouraged. © 2014 M. Evans et al. CBE—Life Sciences Education © 2014 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

First detection of anti-Besnoitia spp. specific antibodies in horses and donkeys in Italy.

PubMed

Villa, Luca; Gazzonis, Alessia Libera; Álvarez-García, Gema; Diezma-Díaz, Carlos; Zanzani, Sergio Aurelio; Manfredi, Maria Teresa

2018-06-20

Among Apicomplexa protozoa infecting equids, Besnoitia spp., Toxoplasma gondii and Neospora spp. represent important issues from a sanitary and zootechnical viewpoint. However, only scarce epidemiological data are available on the spread of the infections in horses and donkeys in Europe. Therefore, a serosurvey was planned to estimate the prevalence of these Sarcocystidae species in Italian equids. Serum samples from 268 horses and 18 donkeys raised in Italy were collected and serologically analyzed to detect anti-Besnoitia spp., anti-T. gondii and anti-Neospora spp. antibodies: an approach based on an initial screening by in-house ELISA followed by a confirmatory WB was used. Two horses (0.7%) and four donkeys (22.2%), showed antibodies anti-Besnoitia spp. Ten horses (3.7%) resulted positive to T. gondii and one of these (0.4%) was seropositive also to Neospora spp. This is the first detection of anti-Besnoitia spp. specific antibodies in Italian horses and donkeys. The study confirmed the circulation of Besnoitia spp. among equids in Europe. Low prevalence of T. gondii and Neospora spp. in horses raised in Italy was reported. Nevertheless, it is noteworthy to consider that consumption of horse meat could represent a source for human toxoplasmosis. Copyright © 2018. Published by Elsevier B.V.

[Ethical issues raised by 2 kinds of protocols for organ donation after cardiac death: aspects particular to France, Spain and the United States].

PubMed

Tortosa, Jean-Christophe; Rodríguez-Arias Vailhen, David; Moutel, Grégoire

2010-02-01

France, Spain and US are three leader countries in activity of organ procurement and transplantation. Donation after cardiac death is one of the strategies they have been implemented in order to face organ shortage. Donation after cardiac death is internationally considered to be an encouraging source of organs for transplantation both because of its capacity to significantly increase the donor pool and because of the quality of the organs obtained from non-heart-beating organ donors. These protocols give rise to important ethical issues that have been widely discussed in the international literature. The aim of this paper is to identify and discuss the ethical issues that these protocols raise in these three countries.

Ethics for pandemics beyond influenza: Ebola, drug-resistant tuberculosis, and anticipating future ethical challenges in pandemic preparedness and response.

PubMed

Smith, Maxwell J; Silva, Diego S

2015-01-01

The unprecedented outbreak of Ebola virus disease (EVD) in West Africa has raised several novel ethical issues for global outbreak preparedness. It has also illustrated that familiar ethical issues in infectious disease management endure despite considerable efforts to understand and mitigate such issues in the wake of past outbreaks. To improve future global outbreak preparedness and response, we must examine these shortcomings and reflect upon the current state of ethical preparedness. To this end, we focus our efforts in this article on the examination of one substantial area: ethical guidance in pandemic plans. We argue that, due in part to their focus on considerations arising specifically in relation to pandemics of influenza origin, pandemic plans and their existing ethical guidance are ill-equipped to anticipate and facilitate the navigation of unique ethical challenges that may arise in other infectious disease pandemics. We proceed by outlining three reasons why this is so, and situate our analysis in the context of the EVD outbreak and the threat posed by drug-resistant tuberculosis: (1) different infectious diseases have distinct characteristics that challenge anticipated or existing modes of pandemic prevention, preparedness, response, and recovery, (2) clear, transparent, context-specific ethical reasoning and justification within current influenza pandemic plans are lacking, and (3) current plans neglect the context of how other significant pandemics may manifest. We conclude the article with several options for reflecting upon and ultimately addressing ethical issues that may emerge with different infectious disease pandemics.

Ethics and policy in embryonic stem cell research.

PubMed

Robertson, John A

1999-06-01

Embryonic stem cells, which have the potential to save many lives, must be recovered from aborted fetuses or live embyros. Although tissue from aborted fetuses can be used without moral complicity in the underlying abortion, obtaining stem cells from embryos necessarily kills them, thus raising difficult questions about the use of embryonic human material to save others. This article draws on previous controversies over embryo research and distinctions between intrinsic and symbolic moral status to analyze these issues. It argues that stem cell research with spare embryos produced during infertility treatment, or even embryos created specifically for research or therapeutic purposes, is ethically acceptable and should receive federal funding.

[Differential diagnosis of febrile exanthema].

PubMed

Aramă, St S; Anca, Ioana Alina; Munteanu, Daniela-Ioana; Aramă, Victoria; Hristea, Adriana; Moroti, Ruxandra; Ion, Daniela Adriana

2007-01-01

Febrile exanthema (FE) is an extremely polymorphous clinical entity, frequently seen in daily clinical practice. FE is characterized by diffuse rash and fever. FE is classified in 4 types, depending on the primary skin lesion: macular, maculopapular, vesicular, and bullous exanthema. It is of infectious and non-infectious cause. Among the infectious causes the most frequent is the viral one. FE may affect all ages, but especially children and young people. Usually, FE raises important issues of differential diagnosis, because its clinical and etiological complexity. To decide the most appropriate therapeutic and prophylactic measures for FE, it is important to know the clinical criteria and the specific diagnostic methods.

[Non adherence and topical steroids].

PubMed

Aubert, H; Barbarot, S

2012-01-01

Compliance raises very specific questions in dermatology related to the frequent use of local treatments: creams or ointments, including topical corticosteroids. The adherence in dermatology is a complex issue. It is difficult to quantify objectively because of the patient subjectivity, the constant adaptation to changes in the course of the disease, and due to the lack of adapted device. Moreover poor compliance may be related to topical corticosteroid phobia, defined as a fear vis-à-vis the topical corticosteroids, rational or not. The topical corticosteroid phobia is very common in the management of chronic inflammatory skin diseases especially in atopic dermatitis. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

Self-plagiarism in academic publishing: the anatomy of a misnomer.

PubMed

Andreescu, Liviu

2013-09-01

The paper discusses self-plagiarism and associated practices in scholarly publishing. It approaches at some length the conceptual issues raised by the notion of self-plagiarism. It distinguishes among and then examines the main families of arguments against self-plagiarism, as well as the question of possibly legitimate reasons to engage in this practice. It concludes that some of the animus frequently reserved for self-plagiarism may be the result of, among others, poor choice of a label, unwarranted generalizations as to its ill effects based on the specific experience (and goals) of particular disciplines, and widespread but not necessarily beneficial publishing practices.

Internationalizing the University Mathematics Curriculum

ERIC Educational Resources Information Center

Appelbaum, Peter; Friedler, Louis M.; Ortiz, Carlos E.; Wolff, Edward F.

2009-01-01

This article offers suggestions for achieving the internationalization of university mathematics-related curricular offerings. It presents learning objectives and related student outcomes, raises general issues related to internationalization, and then discusses how to incorporate the objectives and address these issues within the university…

Suggestions for Rethinking Validation

ERIC Educational Resources Information Center

Fisher, William P., Jr.

2017-01-01

In this commentary on "Rethinking Traditional Methods of Survey Validation," found in this issue of "Measurement: Interdisciplinary Research and Perspectives," William Fisher writes that Maul's paper raises issues of validity in survey-based measurement that deserve far wider consideration and scrutiny than they typically…

Evaluating the effectiveness of Washington state repeated job search services on the employment rate of prime-age female welfare recipients☆

PubMed Central

Hsiao, Cheng; Shen, Yan; Wang, Boqing; Weeks, Greg

2014-01-01

This paper uses an unbalanced panel dataset to evaluate how repeated job search services (JSS) and personal characteristics affect the employment rate of the prime-age female welfare recipients in the State of Washington. We propose a transition probability model to take into account issues of sample attrition, sample refreshment and duration dependence. We also generalize Honoré and Kyriazidou’s [Honoré, B.E., Kyriazidou, E., 2000. Panel data discrete choice models with lagged dependent variables. Econometrica 68 (4), 839–874] conditional maximum likelihood estimator to allow for the presence of individual-specific effects. A limited information test is suggested to test for selection issues in non-experimental data. The specification tests indicate that the (conditional on the set of the confounding variables considered) assumptions of no selection due to unobservables and/or no unobserved individual-specific effects are not violated. Our findings indicate that the first job search service does have positive and significant impacts on the employment rate. However, providing repeated JSS to the same client has no significant impact. Further, we find that there are significant experience-enhancing effects. These findings suggest that providing one job search services training to individuals may have a lasting impact on raising their employment rates. PMID:26052178

Evaluating the effectiveness of Washington state repeated job search services on the employment rate of prime-age female welfare recipients.

PubMed

Hsiao, Cheng; Shen, Yan; Wang, Boqing; Weeks, Greg

2008-07-01

This paper uses an unbalanced panel dataset to evaluate how repeated job search services (JSS) and personal characteristics affect the employment rate of the prime-age female welfare recipients in the State of Washington. We propose a transition probability model to take into account issues of sample attrition, sample refreshment and duration dependence. We also generalize Honoré and Kyriazidou's [Honoré, B.E., Kyriazidou, E., 2000. Panel data discrete choice models with lagged dependent variables. Econometrica 68 (4), 839-874] conditional maximum likelihood estimator to allow for the presence of individual-specific effects. A limited information test is suggested to test for selection issues in non-experimental data. The specification tests indicate that the (conditional on the set of the confounding variables considered) assumptions of no selection due to unobservables and/or no unobserved individual-specific effects are not violated. Our findings indicate that the first job search service does have positive and significant impacts on the employment rate. However, providing repeated JSS to the same client has no significant impact. Further, we find that there are significant experience-enhancing effects. These findings suggest that providing one job search services training to individuals may have a lasting impact on raising their employment rates.

Questioning the evidence for a claim in a socio-scientific issue: an aspect of scientific literacy

NASA Astrophysics Data System (ADS)

Roberts, Ros; Gott, Richard

2010-11-01

Understanding the science in a 'socio-scientific issue' is at the heart of the varied definitions of 'scientific literacy'. Many consider that understanding evidence is necessary to participate in decision making and to challenge the science that affects people's lives. A model is described that links practical work, argumentation and scientific literacy which is used as the basis of this research. If students are explicitly taught about evidence does this transfer to students asking questions in the context of a local socio-scientific issue? What do they ask questions about? Sixty-five primary teacher training students were given the pre-test, before being taught the 'concepts of evidence' and applying them in an open-ended investigation and were tested again 15 weeks later. Data were coded using Toulmin's argument pattern (TAP) and the 'concepts of evidence'. After the intervention it was found that, in relation to a socio-scientific issue, they raised significantly more questions specifically about the evidence that lead to the scientists' claims although questions explicitly targeting the quality of the data were still rare. This has implications for curricula that aim for scientific literacy.

The Teaching of Socioscientific Issues in Interdisciplinarity Biology-philosophy, an Ethical Stake and Citizenship Issue

ERIC Educational Resources Information Center

Kacem, Saida; Simonneaux, Laurence

2009-01-01

This research starts from a relatively optimistic thinking based on the fact that the teaching of the socioscientific issues through the practice of argued debates can contribute positively towards education in scientific citizenship. The teaching of techno-sciences raises topical questions which interfere in the classroom and at the same time…

Fundamental Issues Concerning the Sustainment and Scaling Up of Professional Development Programs

ERIC Educational Resources Information Center

Tirosh, Dina; Tsamir, Pessia; Levenson, Esther

2015-01-01

The issue of sustaining and scaling up professional development for mathematics teachers raises several fundamental issues for researchers. This commentary addresses various definitions for sustainability and scaling up and how these definitions may affect the design of programs as well as the design of research. We consider four of the papers in…

Critical Issues for Teacher Educators and Literacy Specialists: A View from Higher Education in New York

ERIC Educational Resources Information Center

Goatley, Virginia

2008-01-01

This article outlines five critical issues for teacher educators and literacy specialists in New York State. Intended to raise issues and share recent policy decisions, the article provides background and conversations about current policy. Readers are encouraged to make decisions about how to participate in the current conversations across the…

Systems Engineering

DTIC Science & Technology

1989-05-01

Faced with complaints about lengthy and costly developments , rapid obsolescence, and excessive costs of ownership, we have all heard the following...microwave integrated circuits raises similar system and sub-system issues. Microprocessor developments raise new questions regarding the trade-offs between...imply the need for and utilization of more specialists, but future avionics developments will also require systems-oriented engineess. By definition

An Education Grounded in Biology: Interdisciplinary and Ethical Considerations

ERIC Educational Resources Information Center

Gardner, Howard

2009-01-01

Work in the new area of Mind, Brain, and Education (MBE) raises epistemological and ethical issues. With respect to epistemology, the norms of the component disciplines must be honored and the resulting amalgam must be more than a mere sum of the parts. With respect to ethics, the roles of scientist, educator, and practitioner each raise ethical…

Raising Empathetic Children in a Post-9-11 Climate of Uncertainty.

ERIC Educational Resources Information Center

Lantieri, Linda

2002-01-01

Discusses how to use world events such as the September 11th attacks to nurture the development of empathy and compassion in children, suggesting what families can do to foster empathy (e.g., build safe, caring, and respectful homes; provide opportunities to talk about thoughts and feelings; encourage thoughtful dialogue about issues raised by the…

The Politics of Invasive Weed Management: Gender, Race, and Risk Perception in Rural California

ERIC Educational Resources Information Center

Norgaard, Kari Marie

2007-01-01

"Biological invasions" are now recognized as the cause of significant ecological and economic damage. They also raise a series of less visible social issues. Management of invasive species is often a political process raising questions such as who decides which organisms are to be managed, and who benefits or is affected by different…

Emerging Issues and Critical Trends Affecting Fund Raising by Community Colleges.

ERIC Educational Resources Information Center

Anderson, Spencer

This paper discusses fund raising in America's community colleges. During 1997, approximately 1,755 two-year colleges in the United States enrolled more than 5.4 million first-time college freshmen, or 46% of the total students in higher education. However, these colleges received only five percent of the private financial support given to…

Math, Science, and Web-Based Activities to Raise Awareness about Nutrition and Obesity

ERIC Educational Resources Information Center

Zuercher, Deborah K.

2011-01-01

The incidence of child obesity in the United States is increasing at an alarming rate. This article provides information about nutrition, obesity, and related health conditions and suggests some classroom activities to raise awareness about these issues and empower students to live healthier, more active lives. A list of recommended health-related…

24 CFR 1720.255 - Amendments and supplemental pleadings.

Code of Federal Regulations, 2011 CFR

2011-04-01

... proceedings are tried by express or implied consent of the parties, they shall be treated in all respects as if they had been raised in the pleadings; and such amendments of the pleadings as may be necessary to make them conform to the evidence and to raise such issues shall be allowed at any time. (c...

Staff Smart: Keep the Best Teachers in Connecticut's Classrooms. A ConnCAN Issue Brief

ERIC Educational Resources Information Center

ConnCAN, 2011

2011-01-01

The research is clear: teachers are the most important factor in raising student achievement in schools. If Connecticut is serious about closing our worst-in-the-nation achievement gap and raising academic performance for all students, there must be an excellent teacher in every classroom. Connecticut's budget crisis will likely lead to widespread…

The Octopus, the Squid and the Tortoise

ERIC Educational Resources Information Center

Caruth, Gail D.; Caruth, Donald L.

2013-01-01

What is the role of the Doctor of Philosophy (PhD) today? This is not a new question. In 1903, William James questioned the value of the degree as an indicator of teaching ability. Unfortunately, the issue James raised has never been resolved. Move forward in time to 1990. Theodore Ziolkowski essentially agreed with James, but raised additional…

[Preclinical evaluation of the safety of biotechnology products: specific aspects].

PubMed

Descotes, Jacques; Ravel, Guillaume; Vial, Thierry

2003-01-01

Biotechnology-derived products represent a class of increasingly numerous drugs. One of their major characteristics is extreme diversity, which requires specific approaches for the preclinical evaluation of their safety. The selection of relevant animal species is not easy, as most of these products are human-specific. Thus, only one species will often be used, i.e. primates. As most of these products are large molecules, they can be directly immunogenic. When they are human-specific, no animal model is available to predict the risk. Many biotechnology-derived products have an expected influence on the immune system. This must be taken into account in the preclinical strategy of immunotoxicity evaluation that is now required for every new drug. As conventional toxicity testing is generally limited, safety pharmacology studies should include more than the core battery of assays required by current guidelines in order to complement missing data as much as possible. Because of these particularities, a comprehensive investigation of metabolism and pharmacokinetics is not usually needed. Some products can cross-react with cellular components not intended as therapeutic targets. It is, therefore, essential to rule out the risk of possible cross-reactions that can result in adverse effects. Finally, viral safety is a crucial component of the preclinical safety evaluation of these products. Overall, biotechnology-derived products raise specific issues because of their innovative and original characteristics, and it is difficult to address all these issues if not by using a case-by-case approach.

Personal genome testing: Test characteristics to clarify the discourse on ethical, legal and societal issues

PubMed Central

2011-01-01

Background As genetics technology proceeds, practices of genetic testing have become more heterogeneous: many different types of tests are finding their way to the public in different settings and for a variety of purposes. This diversification is relevant to the discourse on ethical, legal and societal issues (ELSI) surrounding genetic testing, which must evolve to encompass these differences. One important development is the rise of personal genome testing on the basis of genetic profiling: the testing of multiple genetic variants simultaneously for the prediction of common multifactorial diseases. Currently, an increasing number of companies are offering personal genome tests directly to consumers and are spurring ELSI-discussions, which stand in need of clarification. This paper presents a systematic approach to the ELSI-evaluation of personal genome testing for multifactorial diseases along the lines of its test characteristics. Discussion This paper addresses four test characteristics of personal genome testing: its being a non-targeted type of testing, its high analytical validity, low clinical validity and problematic clinical utility. These characteristics raise their own specific ELSI, for example: non-targeted genetic profiling poses serious problems for information provision and informed consent. Questions about the quantity and quality of the necessary information, as well as about moral responsibilities with regard to the provision of information are therefore becoming central themes within ELSI-discussions of personal genome testing. Further, the current low level of clinical validity of genetic profiles raises questions concerning societal risks and regulatory requirements, whereas simultaneously it causes traditional ELSI-issues of clinical genetics, such as psychological and health risks, discrimination, and stigmatization, to lose part of their relevance. Also, classic notions of clinical utility are challenged by the newer notion of 'personal utility.' Summary Consideration of test characteristics is essential to any valuable discourse on the ELSI of personal genome testing for multifactorial diseases. Four key characteristics of the test - targeted/non-targeted testing, analytical validity, clinical validity and clinical utility - together determine the applicability and the relevance of ELSI to specific tests. The paper identifies and discusses four areas of interest for the ELSI-debate on personal genome testing: informational problems, risks, regulatory issues, and the notion of personal utility. PMID:21672210

Video Display Terminals: Radiation Issues.

ERIC Educational Resources Information Center

Murray, William E.

1985-01-01

Discusses information gathered in past few years related to health effects of video display terminals (VDTs) with particular emphasis given to issues raised by VDT users. Topics covered include radiation emissions, health concerns, radiation surveys, occupational radiation exposure standards, and long-term risks. (17 references) (EJS)

77 FR 38495 - Safety Zone; Village of Sodus Point Fireworks Display, Sodus Bay, Sodus Point, NY

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-28

.... Regulatory History and Information The Coast Guard is issuing this temporary final rule without prior notice... of any grant or loan recipients, and will not raise any novel legal or policy issues. The safety zone...

Thinking clearly about the FIRST trial: addressing ethical challenges in cluster randomised trials of policy interventions involving health providers.

PubMed

Horn, Austin R; Weijer, Charles; Hey, Spencer Phillips; Brehaut, Jamie; Fergusson, Dean A; Goldstein, Cory E; Grimshaw, Jeremy; Taljaard, Monica

2018-04-27

The ethics of the Flexibility In duty hour Requirements for Surgical Trainees (FIRST) trial have been vehemently debated. Views on the ethics of the FIRST trial range from it being completely unethical to wholly unproblematic. The FIRST trial illustrates the complex ethical challenges posed by cluster randomised trials (CRTs) of policy interventions involving healthcare professionals. In what follows, we have three objectives. First, we critically review the FIRST trial controversy, finding that commentators have failed to sufficiently identify and address many of the relevant ethical issues. The 2012 Ottawa Statement on the Ethical Design and Conduct of Cluster Randomized Trials provides researchers and research ethics committees with specific guidance for the ethical design and conduct of CRTs. Second, we aim to demonstrate how the Ottawa Statement provides much-needed clarity to the ethical issues in the FIRST trial, including: research participant identification; consent requirements; gatekeeper roles; benefit-harm analysis and identification of vulnerable participants. We nonetheless also find that the FIRST trial raises ethical issues not adequately addressed by the Ottawa Statement. Hence, third and finally, we raise important questions requiring further ethical analysis and guidance, including: Does clinical equipoise apply to policy interventions with little or no evidence-base? Do healthcare providers have an obligation to participate in research? Does the power-differential in certain healthcare settings render healthcare providers vulnerable to duress and coercion to participant in research? If so, what safeguards might be implemented to protect providers, while allowing important research to proceed? © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Development of ITS sequence based molecular marker to distinguish, Tribulus terrestris L. (Zygophyllaceae) from its adulterants.

PubMed

Balasubramani, Subramani Paranthaman; Murugan, Ramar; Ravikumar, Kaliamoorthy; Venkatasubramanian, Padma

2010-09-01

Tribulus terrestris L. (Zygophyllaceae) is one of the highly traded raw drugs and also used as a stimulative food additive in Europe and USA. While, Ayurvedic Pharmacopoeia of India recognizes T. terrestris as Goksura, Tribulus lanuginosus and T. subramanyamii are also traded by the same name raising issues of quality control. The nuclear ribosomal RNA genes and ITS (internal transcribed spacer) sequence were used to develop species-specific DNA markers. The species-specific markers efficiently amplified 295bp for T. terrestris (TT1F and TT1R), 300bp for T. lanuginosus (TL1F and TL1R) and 214bp for T. subramanyamii (TS1F and TS1R). These DNA markers can be used to distinguish T. terrestris from its adulterants. Copyright (c) 2010 Elsevier B.V. All rights reserved.

Rethinking foundations of language from a multidisciplinary perspective.

PubMed

Gong, Tao; Shuai, Lan; Wu, Yicheng

2018-04-21

The issue of language foundations has been of great controversy ever since it was first raised in Lenneberg's (1967) monograph Biological Foundations of Language. Based on a survey of recent findings relevant to the study of language acquisition and evolution, we propose that: (i) the biological predispositions for language are largely domain-general, not necessarily language-specific or human-unique; (ii) the socio-cultural environment of language serves as another important foundation of language, which helps shape language components, induce and drive language shift; and (iii) language must have coevolved with the cognitive mechanisms associated with it through intertwined biological and cultural evolution. In addition to theoretical issues, this paper also evaluates the primary approaches recently joining the endeavor of studying language foundations and evolution, including human experiments and computer simulations. Most of the evidence surveyed in this paper comes from a variety of disciplines, and methodology therein complements each other to form a global picture of language foundations. These reflect the complexity of the issue of language foundations and the necessity of taking a multidisciplinary perspective to address it. Copyright © 2018 Elsevier B.V. All rights reserved.

Standardisation in the field of nanotechnology: some issues of legitimacy.

PubMed

Forsberg, Ellen-Marie

2012-12-01

Nanotechnology will allegedly have a revolutionary impact in a wide range of fields, but has also created novel concerns about health, safety and the environment (HSE). Nanotechnology regulation has nevertheless lagged behind nanotechnology development. In 2004 the International Organization for Standardization established a technical committee for producing nanotechnology standards for terminology, measurements, HSE issues and product specifications. These standards are meant to play a role in nanotechnology development, as well as in national and international nanotechnology regulation, and will therefore have consequences for consumers, workers and the environment. This paper gives an overview of the work in the technical committee on nanotechnology and discusses some challenges with regard to legitimacy in such work. The paper focuses particularly on stakeholder involvement and the potential problems of scientific robustness when standardising in such early stages of the scientific development. The intention of the paper is to raise some important issues rather than to draw strong conclusions. However, the paper will be concluded with some suggestions for improving legitimacy in the TC 229 and a call for increased public awareness about standardisation in the field of nanotechnology.

Use of a web site to increase knowledge and awareness of hunger-related issues.

PubMed Central

Jennings, Sharla; Cotugna, Nancy; Vickery, Connie E.

2003-01-01

The purpose of this study was to determine the current level of knowledge and awareness of hunger-related issues among a convenience sample of Delawareans. We also assessed whether raising knowledge and awareness of the hunger problem through the FBD's newly designed web site would encourage participation in antihunger activities. Via e-mail, 1,719 individuals were invited to participate in a three-phase, online survey, and 392 agreed. Phase-I questions were answered prior to viewing the web site, phase II (n=217) immediately afterward, and phase III (n=61) six weeks later. Responses indicated a high level of awareness about general hunger issues but specific knowledge proved to be at a lower level. No statistically significant differences were noted when data were collapsed across gender, age, educational level, or work setting. In a six-week post-survey, 41% of subjects were motivated by the web site to engage in an antihunger activity; 34% had told others about the web site and indicated it may be a useful tool in antihunger outreach efforts for the FBD. PMID:14651376

Ethical Issues in the Use of Extracorporeal Membrane Oxygenation in Controlled Donation After Circulatory Determination of Death.

PubMed

Dalle Ave, A L; Shaw, D M; Bernat, J L

2016-08-01

The use of donor extracorporeal membrane oxygenation (ECMO) to improve graft outcomes by some controlled donation after circulatory determination of death (cDCDD) programs raises ethical issues. We reviewed cDCDD protocols using ECMO and the relevant ethics literature to analyze these issues. It is not obvious that ECMO in cDCDD improves graft outcomes. In our opinion, ECMO implemented before death can interfere with end-of-life care and damage bodily integrity. By restoring systemic circulation, ECMO risks invalidating the preceding declaration of death if brain and cardiac perfusion is not adequately excluded because of malfunction or misplacement of the supradiaphragmatic aortic occlusion balloon. The use of ECMO is not compatible with the acronym DCDD because circulation is restored after the determination of death. Because of these deficiencies, we concluded that other techniques are preferable, such as rapid recovery or in situ cold infusion. If ECMO is performed, it requires a specific informed consent and transparency. © Copyright 2016 The American Society of Transplantation and the American Society of Transplant Surgeons.

Reproducibility and replicability of rodent phenotyping in preclinical studies.

PubMed

Kafkafi, Neri; Agassi, Joseph; Chesler, Elissa J; Crabbe, John C; Crusio, Wim E; Eilam, David; Gerlai, Robert; Golani, Ilan; Gomez-Marin, Alex; Heller, Ruth; Iraqi, Fuad; Jaljuli, Iman; Karp, Natasha A; Morgan, Hugh; Nicholson, George; Pfaff, Donald W; Richter, S Helene; Stark, Philip B; Stiedl, Oliver; Stodden, Victoria; Tarantino, Lisa M; Tucci, Valter; Valdar, William; Williams, Robert W; Würbel, Hanno; Benjamini, Yoav

2018-04-01

The scientific community is increasingly concerned with the proportion of published "discoveries" that are not replicated in subsequent studies. The field of rodent behavioral phenotyping was one of the first to raise this concern, and to relate it to other methodological issues: the complex interaction between genotype and environment; the definitions of behavioral constructs; and the use of laboratory mice and rats as model species for investigating human health and disease mechanisms. In January 2015, researchers from various disciplines gathered at Tel Aviv University to discuss these issues. The general consensus was that the issue is prevalent and of concern, and should be addressed at the statistical, methodological and policy levels, but is not so severe as to call into question the validity and the usefulness of model organisms as a whole. Well-organized community efforts, coupled with improved data and metadata sharing, have a key role in identifying specific problems and promoting effective solutions. Replicability is closely related to validity, may affect generalizability and translation of findings, and has important ethical implications. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Employee Health in the Mental Health Workplace: Clinical, Administrative, and Organizational Perspectives.

PubMed

Shah, Jai L; Kapoor, Reena; Cole, Robert; Steiner, Jeanne L

2016-04-01

Issues of mental health and employee health have risen to increasing prominence in recent years. However, there have been few explorations of the clinical and administrative challenges that these issues raise, particularly in settings that are themselves mental health workplaces. In order to identify and understand such challenges, a brief case of acute employee illness in a mental health workplace is described followed by a discussion of salient clinical, administrative, and organizational considerations. The case raises questions about medicolegal responsibilities and relationships between clinicians and patients in mental health settings, illuminates tensions between clinical staff and human resources processes, and draws attention to the need for illness prevention and mental health promotion initiatives in the workplace. Increased awareness of these issues, complications, and potential solutions would benefit clinicians, administrators, and mental health institutions.

Policy Issues in Interactive Cable Television.

ERIC Educational Resources Information Center

Kay, Peg

1978-01-01

Raises several policy issues concerning interactive cable television, including the role of government and the regulation powers, and the implications of telecommunication/social service system concerning privacy and confidentiality, approaches to electronic opinion polling, and the potential widening of the information gap between rich and poor.…

Citizenship, Diversity and Distance Learning: Videoconferencing in Connecticut.

ERIC Educational Resources Information Center

Sembor, Edward C.

1997-01-01

Profiles a videoconference that brought together two seventh-grade classes in Connecticut. Over several days, white, middle-class, rural students discussed topical issues with urban black students. Topics raised included diversity, politics, gun control and local issues. Includes students' responses to the program. (MJP)

Should Hate Be a Crime?

ERIC Educational Resources Information Center

Jacobs, James B.

1993-01-01

Explores issues surrounding hate crime legislation and prosecution, with emphasis on motivation and first amendment issues. Hate crime legislation attempts to import the civil rights model into criminal law, but the very existence of the hate crime label raises social and political stakes in intergroup crimes. (SLD)

Will we outlive our money?

PubMed

Salisbury, D L

2000-01-01

Fewer and fewer Americans retire with benefits in the form of life annuities. The author raises key issues regarding the increased importance that uncertainty plays in determining retirement income. The key issues include longevity risk and how savings withdrawals rates will be affected at varying rates of return.

Addressing Racism

ERIC Educational Resources Information Center

Journal for Research in Mathematics Education, 2013

2013-01-01

This dialogue, extracted from a conversation among some members of the Equity Special Issue Editorial Panel, concerns racism in mathematics education. It raises issues about the use of various terms; about fields of research outside of mathematics education; and about the kinds of racialization processes that occur for students, teachers, and…

16 CFR 3.13 - Adjudicative hearing on issues arising in rulemaking proceedings under the Fair Packaging and...

Code of Federal Regulations, 2010 CFR

2010-01-01

... material to the issues raised by such objections or other issues specified by the Commission. In such case...) Parties. Any person who petitions for issuance, amendment, or repeal of a rule or order, and any person... filed in the proceeding. Upon written application to the Administrative Law Judge and a showing of good...

Cognitive Neuroscience and Mathematics Learning: How Far Have We Come? Where Do We Need to Go?

ERIC Educational Resources Information Center

Ansari, Daniel; Lyons, Ian M.

2016-01-01

In this commentary on the ZDM special issue: "Cognitive neuroscience and mathematics learning--revisited after 5 years," we explore the progress that has been made since ZDM published a similar special issue in 2010. We consider the extent to which future frontiers and methodological concerns raised in the commentary on the 2010 issue by…

Addressing Individual Difficulties in Reading: Issues Relating to Reading Recovery and Pause, Prompt, Praise

ERIC Educational Resources Information Center

Wearmouth, Janice

2004-01-01

Recently the DfES has issued guidance on ways to address the needs of students who experience difficulties in literacy through Wave Three provision in the National Literacy Strategy (DfES, 2002). This guidance raises the issue of what kind of programmes might be initiated in mainstream schools that will improve what is available generally for…

The New Deal: Government and the Economy. Public Issues Series.

ERIC Educational Resources Information Center

Singleton, Laurel R., Ed.

This booklet is part of a series designed to help students take and defend a position on public issues. This unit on the New Deal era raises the following issues: (1) How responsible should the government be for the economic well being of citizens? To what extent should this responsibility outweigh traditional ideas of property rights? (2) What…

The burgeoning science of genetics and the impact on public policy.

PubMed

Hatch, Orrin G

2004-01-01

The legislative branch of government often wrestles with the challenges of public policy issues in the health care area that raise multi-dimensional questions that cut across disciplines of science, law, economics, and ethics. Sometimes the purely scientific issues can be confounding by themselves. This article highlights some key policy issues that require consideration in the post-genome era.

Teaching Ethical Reflexivity in Information Systems: How to Equip Students to Deal with Moral and Ethical Issues of Emerging Information and Communication Technologies

ERIC Educational Resources Information Center

Stahl, Bernd Carsten

2011-01-01

Teaching ethics to students of information systems (IS) raises a number of conceptual and content-related issues. The present paper starts out by developing a conceptual framework of moral and ethical issues that distinguishes between moral intuition, explicit morality, ethical theory and meta-ethical reflection. This conceptual framework…

Developing Communities of Enquiry: Dealing with Social and Ethical Issues in Science at Key Stage 3

ERIC Educational Resources Information Center

Dunlop, Lynda; Humes, Gill; Clarke, Linda; Martin, Valerie McKelvey

2011-01-01

Reproductive technologies, drug discovery and exploration of the universe are areas of contemporary research that raise issues for individuals and society. Forward Thinking, Northern Ireland uses the development of communities of enquiry to promote discussion of these and other social and ethical issues in science with students aged 11-14 years.…

Nursing career fulfillment: statistics and statements from registered nurses.

PubMed

Reineck, Carol; Furino, Antonio

2005-01-01

A state-level survey of registered nurses confirmed national findings and raised new issues. Findings revealed that while nurses love the intrinsic reward of nursing, they report workplace, relationship, and stress issues which contribute to frustration and exhaustion. These issues may prevent registered nurses from giving the nursing care they desire to deliver, hastening preventable retirement and costly turnover decisions.

Practitioner-Raised Issues and End-of-Life Care for Adults with Down Syndrome and Dementia

ERIC Educational Resources Information Center

Watchman, Karen

2005-01-01

The author interviewed a small group of practitioners working in intellectual disability and palliative care settings about their perceptions of a number of end-of-life issues related to people with Down syndrome who were affected by dementia. The study, which took place in Scotland, identified a number of issues and perceptions expressed by the…

Are Australians concerned about nanoparticles? A comparative analysis with established and emerging environmental health issues.

PubMed

Capon, Adam; Rolfe, Margaret; Gillespie, James; Smith, Wayne

2015-02-01

Introducing new technologies into society raises considerable public concern. We determine the public concern about nanoparticles, and compare this concern to other environmental health issues such as wind farms and coal seam gas production. A repeat cross sectional survey examining views on environmental health issues, risk, chemicals and trust was undertaken in more than 1,300 Australian residents in 2000 and 2013. Logistic regression and principal component analysis was used to investigate predictors of nanoparticle concern and identify a component structure for environmental health issues that could explain a trend of future nanoparticle concern. Australians have a relatively low level of concern about the risks of nanoparticles to health when compared to their concerns about other environmental health issues. Items associated with concern included gender, a general wish to avoid chemicals and possibly trust in politicians. Concern over nanoparticles clustered with similar views on technological risks. Current public concern over the risks of nanoparticles is low. However, a reframing of the issue towards 'chemicals' is likely to have a negative effect on risk perceptions. This paper raises questions about appropriate channels for the effective communication of risk. © 2015 Public Health Association of Australia.

Incorporation of Student-Centered, Practical Applications of Geographic Information Systems to Raise Awareness and Generate Solutions for Local Environmental Issues

NASA Astrophysics Data System (ADS)

Bilsley, N. A.; Love, C. A.; Minster, J. B. H.

2014-12-01

Geographic Information Systems (GIS) offer a plethora of applications for numerous fields, from geological sciences to urban planning. Therefore, developing a practical GIS curriculum for students from a diverse selection of majors can be challenging, especially since time constraints presented by the course term limit the number of projects that can cater to each student's academic focus. However, open ended assignments that allow students the freedom to personalize their projects present an opportunity to teach the universal functionality of GIS, as well as stimulate curiosity of students from all backgrounds by allowing them to tailor a project to their personal interests. During an introductory GIS course at the University of California, San Diego, projects prompted students to utilize ArcGIS in ways of their choice that raised awareness of local environmental issues, as well as encouraged students to incorporate environmentally sustainable practices into their lives. In view of the frequently stated interest of students to enter careers where they can use their newly learned GIS skills, the educational platform of choice is ESRI's ArcGIS, but the choice of platform remains flexible. As GIS resources become more accessible with the development of programs such as OpenGIS and OpenStreetMap, the potential for GIS to effectively communicate environmental issues to the public is growing fast. Incorporating these environmental issues into a curriculum not only allows students to personalize their education, but also raises awareness of such problems and provides students with the ability to communicate those issues using GIS.

The British Conservative Government and the Raising of the School Leaving Age, 1959-1964

ERIC Educational Resources Information Center

McCulloch, Gary; Cowan, Steven; Woodin, Tom

2012-01-01

This paper establishes and explains the important role of the Conservative Government of 1959-1964 in supporting the raising of the school leaving age in Britain from the age of 15 to 16. This was a significant and high-profile national issue that generated much educational, social and political debate around conflicting priorities during this…

The More Things Change the More They Stay the Same? A Response to the Audit Commission's Report on Statutory Assessment and Statements of Special Education Needs.

ERIC Educational Resources Information Center

Florian, Lani

2002-01-01

This article addresses issues raised by the British Audit Commission's report on statutory assessment and Statements of Special Educational Needs (SEN). Questions are raised concerning ideas of "special educational needs,""areas of need," and "categories of handicap"; fair distribution of SEN funding; relationships…

Empowering Grandparents Raising Grandchildren: A Training Manual for Group Leaders. Springer Series on Life Styles and Issues in Aging.

ERIC Educational Resources Information Center

Cox, Carole B.

Noting that grandparents in the parenting role are often overwhelmed by the problems of their children, grandchildren, and the social milieu in which they live, this manual presents a 14-session workshop series designed to empower grandparents who are raising their grandchildren alone. Designed to complement "To Grandmother's House We Go and…

Analytical Study of the Status of Myth in the Creation of Literary and Artistic Works

ERIC Educational Resources Information Center

Moghaddam, Sedigheh Sherkat; Abai, Andia

2016-01-01

The prevalent question raised in literary theories has been the quiddity of literature. However, the question of "what is literature?" is a philosophical issue. On the other hand, the relationship between myth and literature has always been raised by most scholars and many have considered literature a subtype of myths. In this paper,…

Knowledge for a Common World? On the Place of Feminist Epistemology in Philosophy of Education

ERIC Educational Resources Information Center

Schumann, Claudia

2016-01-01

The paper discusses the place of feminist epistemology in philosophy of education. Against frequently raised criticisms, the paper argues that the issues raised by feminist standpoint theory lead neither to a reduction of questions of knowledge to questions of power or politics nor to the endorsement of relativism. Within the on-going discussion…

Prenatal whole exome sequencing: the views of clinicians, scientists, genetic counsellors and patient representatives.

PubMed

Quinlan-Jones, Elizabeth; Kilby, Mark D; Greenfield, Sheila; Parker, Michael; McMullan, Dominic; Hurles, Matthew E; Hillman, Sarah C

2016-10-01

Focus groups were conducted with individuals involved in prenatal diagnosis to determine their opinions relating to whole exome sequencing in fetuses with structural anomalies. Five representatives of patient groups/charities (PRGs) and eight clinical professionals (CPs) participated. Three focus groups occurred (the two groups separately and then combined). Framework analysis was performed to elicit themes. A thematic coding frame was identified based on emerging themes. Seven main themes (consent, analysis, interpretation/reinterpretation of results, prenatal issues, uncertainty, incidental findings and information access) with subthemes emerged. The main themes were raised by both groups, apart from 'analysis', which was raised by CPs only. Some subthemes were raised by PRGs and CPs (with different perspectives). Others were raised either by PRGs or CPs, showing differences in patient/clinician agendas. Prenatal consent for whole exome sequencing is not a 'perfect' process, but consent takers should be fully educated regarding the test. PRGs highlighted issues involving access to results, feeling that women want to know all information. PRGs also felt that patients want reinterpretation of results over time, whilst CPs felt that interpretation should be performed at the point of testing only. © 2016 John Wiley & Sons, Ltd. © 2016 John Wiley & Sons, Ltd.

NIOSH comments to DOL on MSHA's advance notice of proposed rulemaking (ANPR) metal and nonmetal mine safety and health, radiation standards by J. D. Millar, March 18, 1985

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1985-03-18

The testimony presents the views of NIOSH with regard to specific issues raised by MSHA in a proposed rulemaking affecting metal and nonmetal mine safety and health, radiation standards. Results are included from epidemiological studies in which the relationship between lung cancer and exposure to radon daughters was examined. A quantitative risk assessment is also noted which will be considered in the development of a NIOSH recommended exposure limit for radon daughters. Specific issues addressed include risk assessment, particularly the relationship and the associated uncertainty between cumulative lifetime radon daughters exposure at or below 120 working level months and themore » lifetime risk of lung cancer or other biological response, and themethodology used to arrive at the risk relationship. The use of a nonthreshold model extrapolating from elevated exposure levels is considered along with modification of the risk relationship to account for cell repair or other factors. Questions concerning the latency period, cigarette smoking, exposure to thoron daughters, exposure to gamma radiation, and exposure to ore dusts are also addressed.« less

Using PROMs to guide patients and practitioners through the head and neck cancer journey

PubMed Central

Rogers, Simon N; Barber, Brittany

2017-01-01

The measurement of patient-reported outcome measures (PROMs) following head and neck cancer (HNC) has the capacity to substantially enhance the care of patients and their care-givers following the diagnosis and treatment of HNC. Literature concerning PROMs has increased exponentially in the past 2 decades, producing a vast array of data upon which the multidisciplinary team can reflect. For this review, “Handle On QOL” has been used as a source of references to illustrate the points raised. PROMs are contextualized by considering the clinically-distinct key stages that cancer patients endure: diagnosis, treatment, acute toxicity, early recovery, late effects, recurrence, and palliation. The PROMs are considered in six main categories: 1) those addressing cornucopia of issues not specific to cancer; 2) those addressing issues common to all cancers; 3) questionnaires with items specific to HNC; 4) questionnaires that focus on a particular aspect of head and neck function; 5) those measuring psychological concerns, such as depression, anxiety, or self-esteem; and 6) item prompt lists. Potential benefits of PROMs in clinical practice are discussed, as are barriers to use. The way forward in integrating PROMs into routine HNC care is discussed with an emphasis on information technology. PMID:29184455

Drug Testing.

ERIC Educational Resources Information Center

Legal Memorandum, 1987

1987-01-01

A number of legal issues are involved in conducting a drug testing program to determine whether students--and occasionally teachers--are using illegal drugs. Two legal issues have been raised concerning the accuracy of the urinalysis test: whether it is chemically accurate and whether appropriate procedures have been followed to make certain that…

Helping Yourself Heal: A Recovering Woman's Guide to Coping with Childhood Abuse Issues

MedlinePlus

... or alcohol. Then you may begin to feel safe enough to think about this issue. However, if the feelings are too overwhelming and painful, or if you feel that you must address them right away, know 3 that you can raise the ...

A Feminist Multicultural Perspective on Supervision

ERIC Educational Resources Information Center

Nelson, Mary Lee; Gizara, Sharon; Hope, Anna Crombach; Phelps, Rosemary; Steward, Robbie; Weitzman, Lauren

2006-01-01

Sixteen members of the Section for the Advancement of Women conference work group identified themes and issues relevant to a feminist multicultural perspective on supervision. Issues raised included feminist silence and White privilege, the importance of self-examination, the courage to be anxious, personal commitment to uncertainty, and isolation…

Great E-xpectations.

ERIC Educational Resources Information Center

Klinger, Donna

2000-01-01

Discusses issues raised in a May 2000 forum on the growing investment by colleges and universities in various electronic businesses, including offering distance education, providing a portal to the Internet, and marketing. Discusses issues concerning the importance of business process redesign, use of E-business as a strategic tool, brand value…

The Ethics of Digital Writing Research: A Rhetorical Approach

ERIC Educational Resources Information Center

McKee, Heidi; Porter, James E.

2008-01-01

The study of writers and writing in digital environments raises distinct and complex ethical issues for researchers. Rhetoric theory and casuistic ethics, working in tandem, provide a theoretical framework for addressing such issues. A casuistic heuristic grounded in rhetorical principles can help digital writing researchers critically…

Issues in the Evaluation of Educational Television Programs

ERIC Educational Resources Information Center

Aversa, Frances M.; Forman, David C.

1978-01-01

Seven issues raised during an evaluation study of televised instructional components are identified: selection and commitment of sample, environment of evaluation sessions, student and expert review, formulation of an explicit evaluation model, conflicting results from different instruments, standards and the interpretation of data, and style and…

Exploring How Globalization Shapes Education: Methodology and Theoretical Framework

ERIC Educational Resources Information Center

Pan, Su-Yan

2010-01-01

This is a commentary on some major issues raised in Carter and Dediwalage's "Globalisation and science education: The case of "Sustainability by the bay"" (this issue), particularly their methodology and theoretical framework for understanding how globalisation shapes education (including science education). While acknowledging the authors'…

Monoallelic Gene Expression in Mammals.

PubMed

Chess, Andrew

2016-11-23

Monoallelic expression not due to cis-regulatory sequence polymorphism poses an intriguing problem in epigenetics because it requires the unequal treatment of two segments of DNA that are present in the same nucleus and that can indeed have absolutely identical sequences. Here, I focus on a few recent developments in the field of monoallelic expression that are of particular interest and raise interesting questions for future work. One development is regarding analyses of imprinted genes, in which recent work suggests the possibility that intriguing networks of imprinted genes exist and are important for genetic and physiological studies. Another issue that has been raised in recent years by a number of publications is the question of how skewed allelic expression should be for it to be designated as monoallelic expression and, further, what methods are appropriate or inappropriate for analyzing genomic data to examine allele-specific expression. Perhaps the most exciting recent development in mammalian monoallelic expression is a clever and carefully executed analysis of genetic diversity of autosomal genes subject to random monoallelic expression (RMAE), which provides compelling evidence for distinct evolutionary forces acting on random monoallelically expressed genes.

The left and right hands of the eighteenth-century British musical prodigies, William Crotch and Samuel Wesley.

PubMed

Snowman, Janet

2010-01-01

The musical prodigy William Crotch (1775-1847) used his left hand for many activities including the playing of stringed instruments, drawing and painting. Information on Crotch's handedness is available in both his own writings and watercolours, and in various portraits. This paper will use Crotch and his handedness to help illuminate how left-handedness was viewed at the end of the eighteenth century, and will also consider the handedness of another near-contemporary musical prodigy, Samuel Wesley (1766-1837). In reflecting on Crotch and Wesley, it is necessary to take account of the Enlightenment background in which they were raised, and the prevalent theories about both education and genius in general, and handedness specifically. A further aspect of great interest is that stringed instruments such as the violin, viola and cello are inherently asymmetric, with one hand bowing and the other fingering strings which are themselves arranged asymmetrically. Crotch himself, described from infancy as "self-taught", raises a number of issues about the "natural" or ergonomically "optimal" way of organising instruments, in particular the cello.

Focus group evaluation of "Secret Feelings": a depression fotonovela for Latinos with limited English proficiency.

PubMed

Cabassa, Leopoldo J; Contreras, Sandra; Aragón, Rebeca; Molina, Gregory B; Baron, Melvin

2011-11-01

In this study, the authors examined reactions of Latino adults with limited English proficiency (LEP) to a culturally and linguistically adapted depression fotonovela, titled "Secret Feelings." Fotonovelas are popular health education tools that use posed photographs, text bubbles with simple text, and dramatic narratives to engage audiences and raise their awareness and knowledge about specific health issues. Four focus groups (N = 32) were conducted at an adult school program (e.g., GED classes). Content analysis was used to generate themes from transcripts and memos. "Secret Feelings" was viewed as an entertaining, engaging, and educational tool that helped combat stigma toward depression and its treatments in the Latino community. Despite learning about depression, participants reported they wanted more information about the causes of depression, the process of recovery, and felt that the story did not shift their apprehensions toward antidepressants. The findings suggest that "Secret Feelings" is a promising depression literacy tool for Latinos with LEP that can raise awareness and knowledge about depression and its treatments, reduce stigma toward depression and antidepressant medications, and model appropriate help-seeking behaviors.

Mental health nursing students' experiences of stress during training: a thematic analysis of qualitative interviews.

PubMed

Galvin, J; Suominen, E; Morgan, C; O'Connell, E-J; Smith, A P

2015-12-01

What is known on the subject? Stress can impact students on mental health nurse training. This can have implications at the individual level (e.g. their own mental health) and at the level of the organization (e.g. sickness absence and attrition). What this paper adds to existing knowledge? We interviewed 12 mental health nursing students regarding the stress they experienced during training. Participants described how the academic demands can at times be unbearable during clinical placements. There were also issues with 'being a student' on some placements, with participants describing negative attitudes towards them from staff. The younger participants reported feeling overwhelmed on their initial placements and described some of the main challenges of mental health work for them. Raising concerns about the quality of care on wards was also described as particularly challenging for the students. What are the implications for practice? This paper can be useful to help training providers support mental health nursing students. Recommendations include reducing academic demands during clinical placements and extending and promoting existing support services beyond normal 9 am-5 pm working hours, even if these services are limited. Younger students could be better supported by being allocated to the more well-resourced placements in the early stages of their training. Raising awareness among staff of the tasks students can and cannot perform can help improve staff/student relations. Finally, students should be educated about the issues around raising concerns on placements to help the government's drive for a more open and transparent National Health Service (NHS). Previous studies investigating stress in nursing students focus on general nursing students or adopt quantitative measures. A qualitative study focusing specifically on mental health nursing students is required. One-to-one interviews were carried out with mental health nursing students (n = 12). Data were thematically analysed. Participants reported unreasonable demands during clinical blocks, and described how control/support is lowest on placements with staff shortages. Negative attitudes towards students from staff and related issues were also discussed. Younger participants described struggling with mental health work during the early stages of training. Training providers should strive to provide adequate support to students to help them manage stress during training. Implications for practice Academic demands should be reasonable during clinical blocks and support services outside normal working hours should be available for students, even if these are limited in scope. Greater consideration to the allocation of placements for younger students in the mental health branch could be helpful. Furthermore, staff on placements should be aware of the tasks students can and cannot perform, to help improve staff/student relations. Educating students on the issues of raising concerns can help the government's drive for a more open and transparent National Health Service (NHS). © 2015 The Authors. Journal of Psychiatric and Mental Health Nursing published by John Wiley & Sons Ltd.

Distributed intelligent control and management (DICAM) applications and support for semi-automated development

NASA Technical Reports Server (NTRS)

Hayes-Roth, Frederick; Erman, Lee D.; Terry, Allan; Hayes-Roth, Barbara

1992-01-01

We have recently begun a 4-year effort to develop a new technology foundation and associated methodology for the rapid development of high-performance intelligent controllers. Our objective in this work is to enable system developers to create effective real-time systems for control of multiple, coordinated entities in much less time than is currently required. Our technical strategy for achieving this objective is like that in other domain-specific software efforts: analyze the domain and task underlying effective performance, construct parametric or model-based generic components and overall solutions to the task, and provide excellent means for specifying, selecting, tailoring or automatically generating the solution elements particularly appropriate for the problem at hand. In this paper, we first present our specific domain focus, briefly describe the methodology and environment we are developing to provide a more regular approach to software development, and then later describe the issues this raises for the research community and this specific workshop.

Universal, developmental, and variable aspects of young children's play: a cross-cultural comparison of pretending at home.

PubMed

Haight, W L; Wang, X L; Fung, H H; Williams, K; Mintz, J

1999-01-01

Using longitudinal data from five Irish American families in the United States and nine Chinese families in Taiwan, in conjunction with an emerging body of evidence in the cultural psychology literature, we propose universal, culturally variable, and developmental dimensions of young children's pretend play. Possible universal dimensions include the use of objects, and the predominantly social nature of pretend play. Developmental dimensions include increases in the proportion of social pretend play initiated by the child, the proportion of partner initiations elaborated upon by the child, and caregivers' use of pretend play initiations to serve other, nonplay social functions. Culturally variable dimensions include the centrality of objects, the participation of specific play partners, the extent of child initiations of social pretend play with caregivers, the various functions of social pretend play in interaction, and specific themes. These findings raise the theoretical issue of how universal and variable dimensions of pretend play interact in specific communities to create distinctive development pathways.

Cirrus clouds and climate feedback: Is the sky falling and should we go tell the king

NASA Technical Reports Server (NTRS)

Stephens, Graeme L.

1990-01-01

It is widely believed that thin cirrus clouds act to enhance the greenhouse effect owing to a particular combination of their optical properties. It is demonstrated how this effect is perhaps based on inadequate resolution of the physics of cirrus clouds and that the more likely impact of cirrus clouds to climate change remains somewhat elusive. These conclusions are developed within the context of a specific feedback mechanism incorporated into a simple mechanistic climate model. A specific scientific question addressed is whether or not the observed relationship between the ice water content and temperature of cirrus provides any significant feedback to the CO2 greenhouse warming. A related question also examined concerns the specific role of cloud microphysics and radiation in this feedback. This raises several pertinent issues about the understanding of cirrus clouds and their likely role in climate change as there presently exists a considerable uncertainty about the microphysics of these clouds (size and shape of ice crystals) and their radiative influences.

Examining Key Issues Underlying the Audit Commission Reports on SEN Policy Paper 1 (5th Series)

ERIC Educational Resources Information Center

Norwich, Brahm; Beek, Chris; Richardson, Penny; Gray, Peter

2004-01-01

This book is the first publication in the fifth series of seminars organised by the SEN Policy Options Steering Group to examine policy issues to do with special educational needs. The aim of the seminar was to examine in depth several underlying issues raised by the recent Audit Commission Reports on special educational needs. The seminar…

Copyright and the Teaching/Learning Process. Issues Analyzed at the Critical Issues Conference 4 (Washington, DC, March 21-23, 1977).

ERIC Educational Resources Information Center

Miller, Jerome K., Ed.

The nine papers in this collection discuss the educational issues raised by the 1976 Copyright Revision Act with special emphasis on conflicts between the rights of teachers and learners and the rights of creators. Topics covered include: (1) the history of copyright development in Europe and America, (2) the educational implications of the new…

Why Minimal Multiple Rules Provide a Unique Window into UG and L2

ERIC Educational Resources Information Center

Amaral, Luiz; Roeper, Tom

2014-01-01

This article clarifies some ideas presented in this issue's keynote article (Amaral and Roeper, this issue) and discusses several issues raised by the contributors' comments on the nature of the Multiple Grammars (MG) theory. One of the key goals of the article is to unequivocally state that MG is not a parametric theory and that its…

Daddies Have Wallets and Mummies Have Purses: Raising Gender Issues with Four- to Five-Year-Olds

ERIC Educational Resources Information Center

Shanker, Heidi L.

2004-01-01

In this article, the author explores gender issues which arose out of a literacy discussion with children in a reception class in a primary school. First an account is given of the discussion. This is followed by an examination of gender-related issues amongst fellow practitioners and parents. Here, the author intends to show the importance of…

Legal and ethical issues in neuroimaging research: human subjects protection, medical privacy, and the public communication of research results.

PubMed

Kulynych, Jennifer

2002-12-01

Humans subjects research entails significant legal and ethical obligations. Neuroimaging researchers must be familiar with the requirements of human subjects protection, including evolving standards for the protection of privacy and the disclosure of risk in "non-therapeutic" research. Techniques for creating veridical surface renderings from volumetric anatomical imaging data raise new privacy concerns, particularly under the federal medical privacy regulation. Additionally, neuroimaging researchers must consider their obligation to communicate research results responsibly. The emerging field of neuroethics should strive to raise awareness of these issues and to involve neuroimaging researchers in the legal, ethical, and policy debates that currently surround human subjects research.

The concept of milk kinship in Islam: issues raised when offering preterm infants of Muslim families donor human milk.

PubMed

El-Khuffash, Afif; Unger, Sharon

2012-05-01

Research has documented health benefits associated with donor human milk (DHM). Offering DHM to people of the Muslim faith raises important religious concerns for these families. Knowledge of these beliefs and an understanding of the rationale for these beliefs enable the health care team to establish rapport and build a foundation of trust with patients and their families, thereby paving the way to developing a treatment plan that is in the best interest of the patients without compromising care. This article describes the issues and a rationale for them and provides physicians caring for preterm infants of Muslim families with information to facilitate advocating DHM to those families.

Coalition Priorité Cancer and the Pharmaceutical Industry in Quebec: Conflicts of Interest in the Reimbursement of Expensive Cancer Drugs?

PubMed Central

Hughes, David; Williams-Jones, Bryn

2013-01-01

In the context of scarce public resources, patient interest groups have increasingly turned to private organizations for financing, including the pharmaceutical industry. This practice puts advocacy groups in a situation of potential conflicts between the interests of patients and those of the drug companies. The interests of patients and industry can converge on issues related to the approval and reimbursement of medications. But even on this issue, interests do not always align perfectly. Using the Quebec example of Coalition Priorité Cancer (CPC) as a case study, we examine the ethical issues raised by such financial relationships in the context of drug reimbursement decision-making. We collected, compiled and analyzed publicly available information on the CPC's organization and activities; this approach allowed us to raise and discuss important questions regarding the possible influence exerted on patient groups by donors. We conclude with some recommendations. PMID:23968674

Intranet technology in hospital information systems.

PubMed

Cimino, J J

1997-01-01

The clinical information system architecture at the Columbia-Presbyterian Medical Center in New York is being incorporated into an intranet using Internet and World Wide Web protocols. The result is an Enterprise-Wide Web which provides more flexibility for access to specific patient information and general medical knowledge. Critical aspects of the architecture include a central data repository and a vocabulary server. The new architecture provides ways of displaying patient information in summary, graphical, and multimedia forms. Using customized links called Infobuttons, we provide access to on-line information resources available on the World Wide Web. Our experience to date has raised a number of interesting issues about the use of this technology for health care systems.

Fallout from the Chernobyl nuclear disaster and congenital malformations in Europe.

PubMed

Hoffmann, W

2001-01-01

Investigators estimate that the population exposure that resulted from the Chernobyl fallout is in the range of natural background radiation for most European countries. Given current radiobiologic knowledge, health effects-if any-would not be measurable with epidemiologic tools. In several independent reports, however, researchers have described isolated peaks in the prevalence of congenital malformations in the cohort conceived immediately after onset of the fallout. The consistency of the time pattern and the specific types of malformation raise concern about their significance. In this study, the author summarizes findings from Turkey, Belarus, Croatia, Finland, Germany, and other countries, and implications for radiation protection and public health issues are discussed.

Integrating Motivational Interviewing and Brief Behavioral Activation Therapy: Theoretical and Practical Considerations

PubMed Central

Balán, Iván C.; Lejuez, C. W.; Hoffer, Marcela; Blanco, Carlos

2017-01-01

Behavioral Activation and specifically the Brief Behavioral Activation Therapy for Depression (BATD) has a strong record of empirical support but its focus on practical out of session activation-based assignments can lead to poor levels of adherence if efforts to enhance motivation are not prioritized. Towards this end, this manuscript describes the assimilative integration of Motivational Interviewing (MI) and BATD to improve clinical outcomes by integrating MI's focus on building and maintaining motivation to change into BATD. The manuscript provides an overview of MI and BATD, theoretical issue raised in integrating the two approaches, and examples of how this integration results in a nondirective and motivation-focused approach to conducting BATD. PMID:29151779

AHRQ series paper 1: comparing medical interventions: AHRQ and the effective health-care program.

PubMed

Slutsky, Jean; Atkins, David; Chang, Stephanie; Sharp, Beth A Collins

2010-05-01

In 2005, the Agency for Healthcare Research and Quality established the Effective Health Care (EHC) Program. The EHC Program aims to provide understandable and actionable information for patients, clinicians, and policy makers. The Evidence-based Practice Centers are one of the cornerstones of the EHC Program. Three key elements guide the EHC Program and thus, the conduct of Comparative Effectiveness Reviews by the EPC Program. Comparative Effectiveness Reviews introduce several specific challenges in addition to the familiar issues raised in a systematic review or meta-analysis of a single intervention. The articles in this series together form the current Methods Guide for Comparative Effectiveness Reviews of the EHC Program.

How Professionally Relevant Can Language Tests Be?: The Author Responds

ERIC Educational Resources Information Center

Wette, Rosemary

2012-01-01

In this article, the author clarifies and comments further on some of the issues raised in John Pill's response to her commentary on "English Proficiency Tests and Communication Skills Training for Overseas-Qualifies Health Professionals in Australia and New Zealand" in the recent special issue of "Language Assessment…

Better Practices for Recruiting T&E Teachers

ERIC Educational Resources Information Center

Love, Tyler S.; Love, Zachary J.; Love, Kevin S.

2016-01-01

The declining number of Technology and Engineering (T&E) educators and teacher preparation programs across the country has been identified as a critical issue plaguing the field for many years (Daugherty, 1998; Volk, 1993). Unfortunately, this issue continues to progress and has raised concerns. Why should middle and high school T&E…

Food & Environment. Teaching Global Issues.

ERIC Educational Resources Information Center

Gage, Susan

1989-01-01

Through articles and activities designed for the senior secondary level, students examine the food production system in British Columbia and the world and explore creative, sustainable alternatives for food production. A description of raising food in the first world with the critical issues of energy use and environmental degradation precedes a…

Working with Child Prostitutes in Thailand: Problems of Practice and Interpretation

ERIC Educational Resources Information Center

Montgomery, Heather

2007-01-01

Conducting anthropological fieldwork on the emotive issue of child prostitution raises difficult issues for anthropologists and other researchers. This article examines the ethical dilemmas of working with these extremely vulnerable children, focusing on the difference between the researcher's own interpretations and those given by the children…

Commentary: Minimizing Evaluation Misuse as Principled Practice

ERIC Educational Resources Information Center

Cousins, J. Bradley

2004-01-01

"Ethical Challenges," in my experience, is invariably interesting, often instructive and sometimes amusing. Some of the most engaging stimulus scenarios raise thorny evaluation practice issues that ultimately lead to disparate points of view about the nature of the issue and how to handle it (Datta, 2002; Smith, 2002). Despite my poor performance…

Moral Development in the Information Age.

ERIC Educational Resources Information Center

Willard, Nancy

This paper presents a preliminary overview of moral development issues that are raised when young people interact in cyberspace. A preliminary classification system of Internet ethics issues that parents and educators must address includes: (1) respect for property, (2) respect for territory and privacy, (3) respect for others and common courtesy,…

ACHP | News

Science.gov Websites

high-performance building district. The Seattle 2030 District recently was chosen as one of the first community partners in the Department of Energy’s Better Buildings Challenge. They saw examples of the Section 106. The discussion was important in identifying a number of issues. One issue raised was that

Issues and Concerns of Assessment for English Language Learners with Learning Disabilities

ERIC Educational Resources Information Center

Pichardo, Blanca

2014-01-01

Limited research has been accomplished within the past few years regarding issues and concerns of assessment for English Language Learners (ELL) with Learning Disabilities (LD). The increasing number of this unique population throughout schools has raised many concerns for professionals in education. English Language Learners with Learning…

Failing Boys? Issues in Gender and Achievement.

ERIC Educational Resources Information Center

Epstein, Debbie, Ed.; Elwood, Jannette, Ed.; Hey, Valerie, Ed.; Maw, Janet, Ed.

Issues surrounding boys'"underachievement" have been at the center of public debate about education and the raising of standards in recent years. Media and political responses to the "problem of boys" have tended to be simplistic, partial, and owe more to quick fixes than investigation and research. This book provides a…

Law of Empires.

ERIC Educational Resources Information Center

Martz, Carlton

2001-01-01

This issue of "Bill of Rights in Action" explores issues raised by empires and imperial law. The first article, "Clash of Empires: The Fight for North America," looks at the clash of empires and the fight for North America during the 18th century. The second article, "When Roman Law Ruled the Western World," examines…

Ethical Issues and Best Practice Considerations for Internet Research

ERIC Educational Resources Information Center

Colvin, Jan; Lanigan, Jane

2005-01-01

With rapidly increasing public use of the Internet and advances in Web technologies, family and consumer sciences researchers have the opportunity to conduct Internet-based research. However, online research raises critical ethical issues concerning human subjects that have an impact on research practices. This article provides a review of the…

The IRS Work Plan: IRS Official Identifies Hot Issues.

ERIC Educational Resources Information Center

Owens, Marcus

1993-01-01

A federal tax official specializing in tax-exempt organizations discusses the relatively new use of coordinated examination audits. Significant issues being raised as the use of such audits expands are examined, including employment tax, contractors, withholding on students, unrelated business income, bond financing, the audit process, corporate…

12 CFR 574.7 - Determination by the OTS.

Code of Federal Regulations, 2010 CFR

2010-01-01

... of legal or supervisory issues; (C) The board of directors and executive officers of the holding... the association; (D) The acquisition raises no significant issues of law or policy under then current... frames: (1) On the business day prior to the date of consummation of the acquisition, the chief financial...

National CrossTalk. Volume 13, Number 2, Spring 2005

ERIC Educational Resources Information Center

Trombley, William, Ed.

2005-01-01

The primary purpose of "National CrossTalk" is to stimulate informed discussion and debate of higher education issues. This issue contains the following articles: (1) CUNY [City University of New York] Sheds Reputation as "Tutor U": The Nation's Largest Urban University Raises Standards, and Grapples with Remediation (Jon…

Integrating Augmented Reality Technology to Enhance Children's Learning in Marine Education

ERIC Educational Resources Information Center

Lu, Su-Ju; Liu, Ying-Chieh

2015-01-01

Marine education comprises rich and multifaceted issues. Raising general awareness of marine environments and issues demands the development of new learning materials. This study adapts concepts from digital game-based learning to design an innovative marine learning program integrating augmented reality (AR) technology for lower grade primary…

A Quest for Website Accessibility in Higher Education Institutions

ERIC Educational Resources Information Center

Harper, Kelly A.; DeWaters, Jamie

2008-01-01

Researchers increasingly suggest that accessibility remains a prominent issue across the World Wide Web (www). This study raises awareness about issues of access in higher education. This qualitative research design utilized a listserv that invited university based webmasters to use freeware to evaluate the overall accessibility of their…

The Challenges of Intersectionality: Researching Difference in Physical Education

ERIC Educational Resources Information Center

Flintoff, A.; Fitzgerald, H.; Scraton, S.

2008-01-01

Researching the intersection of class, race, gender, sexuality and disability raises many issues for educational research. Indeed, Maynard (2002, 33) has recently argued that "difference is one of the most significant, yet unresolved, issues for feminist and social thinking at the beginning of the twentieth century". This paper reviews…

Representing Personal Determinants in Causal Structures.

ERIC Educational Resources Information Center

Bandura, Albert

1984-01-01

Responds to Staddon's critique of the author's earlier article and addresses issues raised by Staddon's (1984) alternative models of causality. The author argues that it is not the formalizability of causal processes that is the issue but whether cognitive determinants of behavior are reducible to past stimulus inputs in causal structures.…

Outreach and Program Evaluation: Some Measurement Issues.

ERIC Educational Resources Information Center

Richard, Alan J.; And Others

1996-01-01

The experience of 10 years evaluating HIV risk-reduction intervention for drug users leads to the argument that program outreach workers are part of the intervention continuum and have important effects on service delivery. Improving pre-enrollment data collection will address evaluation issues raised by pre-enrollment outreach contacts. (SLD)

Diversity Digest. Volume 9, Number 3

ERIC Educational Resources Information Center

Musil, Caryn McTighe, Ed.; Hovland, Kevin, Ed.

2006-01-01

This issue of "Diversity Digest" grows out of one recent effort to raise the visibility of science in diversity and global learning initiatives. Articles in this issue include: (1) Science, Diversity, and Global Learning: Untangling Complex Problems (Kevin Hovland); (2) Breaking the Pyramid: Putting Science in the Core (Darcy Kelley);…

Statewide Education Databases: Policy Issues. Discussion Draft.

ERIC Educational Resources Information Center

Hansen, Kenneth H.

This essay reviews current policy issues regarding statewide educational databases. It begins by defining the major characteristics of a database and raising two questions: (1) Is it really necessary to have a statewide educational database? (2) What is the primary rationale for creating one? The limitations of databases in formulating educational…

Teachers and Teaching: Current Issues.

ERIC Educational Resources Information Center

Hart, J. R.

Nine chapters address current issues in teaching, focusing on: (1) "Teacher Quality and Quantity" (James B. Stedman); (2) "Progress Through the Teacher Pipeline" (Robin R. Henke, Xianglei Chen, Sonya Geis, and Paula Knepper); (3) "Raising the Achievement of Low-Performing Students: What High Schools Can Do" (Gene Bottoms); (4) "Knowledge and…

Activists' Influence Tactics and Corporate Policies

ERIC Educational Resources Information Center

de Bakker, Frank G. A.; den Hond, Frank

2008-01-01

Corporations increasingly pay attention to issues of social responsibility, but their policies and procedures to articulate such responsibilities are not just a result of the good will of top management. Often, such policies and procedures are devised because some stakeholders raised their voice on issues relating to the interests of employees,…

Transsexualism: An Issue of Sex-Role Stereotyping.

ERIC Educational Resources Information Center

Raymond, Janice

Transsexualism offers a unique perspective on gender identity, sex-role stereotyping, and sex differences in a patriarchal society. It is also an important medical ethical issue which raises questions of bodily mutilation and integrity, nature versus technology, medical research priorities, unnecessary surgery, and the medical model, as well as…

[Medical research-ethics applied to social sciences: relevance, limits, issues and necessary adjustments].

PubMed

Desclaux, A

2008-04-01

Social sciences are concretely concerned by the ethics of medical research when they deal with topics related to health, since they are subjected to clearance procedures specific to this field. This raises at least three questions: - Are principles and practices of medical research ethics and social science research compatible? - Are "research subjects" protected by medical research ethics when they participate in social science research projects? - What can social sciences provide to on-going debates and reflexion in this field? The analysis of the comments coming from ethics committees about social science research projects, and of the experience of implementation of these projects, shows that the application of international ethics standards by institutional review boards or ethics committees raises many problems in particular for researches in ethnology anthropology and sociology. These problems may produce an impoverishment of research, pervert its meaning, even hinder any research. They are not only related to different norms, but also to epistemological divergences. Moreover, in the case of studies in social sciences, the immediate and differed risks, the costs, as well as the benefits for subjects, are very different from those related to medical research. These considerations are presently a matter of debates in several countries such as Canada, Brasil, and USA. From another hand, ethics committees seem to have developed without resorting in any manner to the reflexion carried out within social sciences and more particularly in anthropology Still, the stakes of the ethical debates in anthropology show that many important and relevant issues have been discussed. Considering this debate would provide openings for the reflexion in ethics of health research. Ethnographic studies of medical research ethics principles and practices in various sociocultural contexts may also contribute to the advancement of medical ethics. A "mutual adjustment" between ethics of medical research and social sciences is presently necessary: it raises new questions open for debate.

Contradictions and Predictions: Two Sources of Uncertainty that Raise the Cognitive Interest of Readers

ERIC Educational Resources Information Center

Campion, Nicolas; Martins, Daniel; Wilhelm, Alice

2009-01-01

Cognitive interest is a motivation to acquire information that is caused by a cognitive and emotional state of uncertainty about the meaning of a text. It can, therefore, be expected to increase if a text raises an issue in readers' mind without resolving it. In support of this expectation, the results of 3 experiments show that the readers'…

An International Look at the Single-Parent: Family Structure Matters More for U.S. Students

ERIC Educational Resources Information Center

Woessmann, Ludger

2015-01-01

When Daniel Patrick Moynihan raised the issue of family structure half a century ago, his concern was the increase in black families headed by women. Since then, the share of children raised in single-parent families in the United States has grown across racial and ethnic groups and with it evidence regarding the impact of family structure on…

Genetic counseling and the ethical issues around direct to consumer genetic testing.

PubMed

Hawkins, Alice K; Ho, Anita

2012-06-01

Over the last several years, direct to consumer(DTC) genetic testing has received increasing attention in the public, healthcare and academic realms. DTC genetic testing companies face considerable criticism and scepticism,particularly from the medical and genetic counseling community. This raises the question of what specific aspects of DTC genetic testing provoke concerns, and conversely,promises, for genetic counselors. This paper addresses this question by exploring DTC genetic testing through an ethic allens. By considering the fundamental ethical approaches influencing genetic counseling (the ethic of care and principle-based ethics) we highlight the specific ethical concerns raised by DTC genetic testing companies. Ultimately,when considering the ethics of DTC testing in a genetic counseling context, we should think of it as a balancing act. We need careful and detailed consideration of the risks and troubling aspects of such testing, as well as the potentially beneficial direct and indirect impacts of the increased availability of DTC genetic testing. As a result it is essential that genetic counselors stay informed and involved in the ongoing debate about DTC genetic testing and DTC companies. Doing so will ensure that the ethical theories and principles fundamental to the profession of genetic counseling are promoted not just in traditional counseling sessions,but also on a broader level. Ultimately this will help ensure that the public enjoys the benefits of an increasingly genetic based healthcare system.

Do we Need a Sociology of Energy Development?

NASA Astrophysics Data System (ADS)

Papatheodorou, Photini; Spathopoulos, Fivos

2016-04-01

The presentation discusses the need of developing a new area of scientific study, namely the "Sociology of Energy Development". It presents our knowledge gaps, regarding the reaction of societies towards energy projects. The presentation proposes that the first steps will be to study the "ethnography" of the energy companies and acquire a clear understanding of their specific cultures. In particular, the presentation argues for a need to raise meaningful questions about the values and attitudes of energy companies in areas such as environmental awareness; gender; cultural differences and other issues of conflict. It will also propose that a new conceptual framework is developed for the specific analysis of the relationship between society and energy companies, in the fields of public perception and trust. Finally, the presentation will conclude with an exploration of key principles, which may guide the development of new ethical practices in the field of energy.

Next steps in research on children exposed to domestic violence.

PubMed

Prinz, Ronald J; Feerick, Margaret M

2003-09-01

The papers in this special issue of Clinical Child and Family Psychology Review provided an overview of what is known about children's exposure to domestic violence, and include indications of gaps in extant research. These gaps and research needs are summarized in this conclusion. Specifically, there is need for further research in several broad areas: definition and measurement of children's exposure to domestic violence; development of research methods and statistical designs that provide detailed information and provide for evidence of intervention effectiveness; impact of domestic violence on parenting and family functioning; the role of child factors and exposure to violence factors in predicting developmental risk and resilience; medical and health consequences of exposure to violence; and the nature of child-system interaction in response to domestic violence. Research needs in these areas are discussed in greater detail, and specific questions are raised for further development.

Sex differences in a human analogue of the Radial Arm Maze: the "17-Box Maze Test".

PubMed

Rahman, Qazi; Abrahams, Sharon; Jussab, Fardin

2005-08-01

This study investigated sex differences in spatial memory using a human analogue of the Radial Arm Maze: a revision on the Nine Box Maze originally developed by called the 17-Box Maze Test herein. The task encourages allocentric spatial processing, dissociates object from spatial memory, and incorporates a within-participants design to provide measures of location and object, working and reference memory. Healthy adult males and females (26 per group) were administered the 17-Box Maze Test, as well as mental rotation and a verbal IQ test. Females made significantly fewer errors on this task than males. However, post hoc analysis revealed that the significant sex difference was specific to object, rather than location, memory measures. These were medium to large effect sizes. The findings raise the issue of task- and component-specific sexual dimorphism in cognitive mapping.

Integrating interface slicing into software engineering processes

NASA Technical Reports Server (NTRS)

Beck, Jon

1993-01-01

Interface slicing is a tool which was developed to facilitate software engineering. As previously presented, it was described in terms of its techniques and mechanisms. The integration of interface slicing into specific software engineering activities is considered by discussing a number of potential applications of interface slicing. The applications discussed specifically address the problems, issues, or concerns raised in a previous project. Because a complete interface slicer is still under development, these applications must be phrased in future tenses. Nonetheless, the interface slicing techniques which were presented can be implemented using current compiler and static analysis technology. Whether implemented as a standalone tool or as a module in an integrated development or reverse engineering environment, they require analysis no more complex than that required for current system development environments. By contrast, conventional slicing is a methodology which, while showing much promise and intuitive appeal, has yet to be fully implemented in a production language environment despite 12 years of development.

Climate change and health effects in Northwest Alaska.

PubMed

Brubaker, Michael; Berner, James; Chavan, Raj; Warren, John

2011-01-01

This article provides examples of adverse health effects, including weather-related injury, food insecurity, mental health issues, and water infrastructure damage, and the responses to these effects that are currently being applied in two Northwest Alaska communities. In Northwest Alaska, warming is resulting in a broad range of unusual weather and environmental conditions, including delayed freeze-up, earlier breakup, storm surge, coastal erosion, and thawing permafrost. These are just some of the climate impacts that are driving concerns about weather-related injury, the spread of disease, mental health issues, infrastructure damage, and food and water security. Local leaders are challenged to identify appropriate adaptation strategies to address climate impacts and related health effects. IMPLEMENTATION PROCESS: The tribal health system is combining local observations, traditional knowledge, and western science to perform community-specific climate change health impact assessments. Local leaders are applying this information to develop adaptation responses. The Alaska Native Tribal Health Consortium will describe relationships between climate impacts and health effects and provide examples of community-scaled adaptation actions currently being applied in Northwest Alaska. Climate change is increasing vulnerability to injury, disease, mental stress, food insecurity, and water insecurity. Northwest communities are applying adaptation approaches that are both specific and appropriate. The health impact assessment process is effective in raising awareness, encouraging discussion, engaging partners, and implementing adaptation planning. With community-specific information, local leaders are applying health protective adaptation measures.

Viral Delivery of dsRNA for Control of Insect Agricultural Pests and Vectors of Human Disease: Prospects and Challenges

PubMed Central

Kolliopoulou, Anna; Taning, Clauvis N. T.; Smagghe, Guy; Swevers, Luc

2017-01-01

RNAi is applied as a new and safe method for pest control in agriculture but efficiency and specificity of delivery of dsRNA trigger remains a critical issue. Various agents have been proposed to augment dsRNA delivery, such as engineered micro-organisms and synthetic nanoparticles, but the use of viruses has received relatively little attention. Here we present a critical view of the potential of the use of recombinant viruses for efficient and specific delivery of dsRNA. First of all, it requires the availability of plasmid-based reverse genetics systems for virus production, of which an overview is presented. For RNA viruses, their application seems to be straightforward since dsRNA is produced as an intermediate molecule during viral replication, but DNA viruses also have potential through the production of RNA hairpins after transcription. However, application of recombinant virus for dsRNA delivery may not be straightforward in many cases, since viruses can encode RNAi suppressors, and virus-induced silencing effects can be determined by the properties of the encoded RNAi suppressor. An alternative is virus-like particles that retain the efficiency and specificity determinants of natural virions but have encapsidated non-replicating RNA. Finally, the use of viruses raises important safety issues which need to be addressed before application can proceed. PMID:28659820

Climate change and health effects in Northwest Alaska

PubMed Central

Brubaker, Michael; Berner, James; Chavan, Raj; Warren, John

2011-01-01

This article provides examples of adverse health effects, including weather-related injury, food insecurity, mental health issues, and water infrastructure damage, and the responses to these effects that are currently being applied in two Northwest Alaska communities. Background In Northwest Alaska, warming is resulting in a broad range of unusual weather and environmental conditions, including delayed freeze-up, earlier breakup, storm surge, coastal erosion, and thawing permafrost. These are just some of the climate impacts that are driving concerns about weather-related injury, the spread of disease, mental health issues, infrastructure damage, and food and water security. Local leaders are challenged to identify appropriate adaptation strategies to address climate impacts and related health effects. Implementation process The tribal health system is combining local observations, traditional knowledge, and western science to perform community-specific climate change health impact assessments. Local leaders are applying this information to develop adaptation responses. Objective The Alaska Native Tribal Health Consortium will describe relationships between climate impacts and health effects and provide examples of community-scaled adaptation actions currently being applied in Northwest Alaska. Findings Climate change is increasing vulnerability to injury, disease, mental stress, food insecurity, and water insecurity. Northwest communities are applying adaptation approaches that are both specific and appropriate. Conclusion The health impact assessment process is effective in raising awareness, encouraging discussion, engaging partners, and implementing adaptation planning. With community-specific information, local leaders are applying health protective adaptation measures. PMID:22022304

Ethical Issues in Measuring Biomarkers in Children’s Environmental Health

PubMed Central

Sly, Peter D.; Eskenazi, Brenda; Pronczuk, Jenny; Šrám, Radim; Diaz-Barriga, Fernando; Machin, Diego Gonzalez; Carpenter, David O.; Surdu, Simona; Meslin, Eric M.

2009-01-01

Background Studying the impact of environmental exposures is important in children because they are more vulnerable to adverse effects on growth, development, and health. Assessing exposure in children is difficult, and measuring biomarkers is potentially useful. Research measuring biomarkers in children raises a number of ethical issues, some of which relate to children as research subjects and some of which are specific to biomarker research. Objective As an international group with experience in pediatric research, biomarkers, and the ethics of research in children, we highlight the ethical issues of undertaking biomarker research in children in these environments. Discussion Significant issues include undertaking research in vulnerable communities, especially in developing countries; managing community expectations; obtaining appropriate consent to conduct the research; the potential conflicts of obtaining permission from an ethics review board in an economically developed country to perform research in a community that may have different cultural values; returning research results to participants and communities when the researchers are uncertain of how to interpret the results; and the conflicting ethical obligations of maintaining participant confidentiality when information about harm or illegal activities mandate reporting to authorities. Conclusion None of these challenges are insurmountable and all deserve discussion. Pediatric biomarker research is necessary for advancing child health. PMID:19672395

Pharmacological cognitive enhancement—how neuroscientific research could advance ethical debate

PubMed Central

Maslen, Hannah; Faulmüller, Nadira; Savulescu, Julian

2014-01-01

There are numerous ways people can improve their cognitive capacities: good nutrition and regular exercise can produce long-term improvements across many cognitive domains, whilst commonplace stimulants such as coffee temporarily boost levels of alertness and concentration. Effects like these have been well-documented in the medical literature and they raise few (if any) ethical issues. More recently, however, clinical research has shown that the off-label use of some pharmaceuticals can, under certain conditions, have modest cognition-improving effects. Substances such as methylphenidate and modafinil can improve capacities such as working memory and concentration in some healthy individuals. Unlike their more mundane predecessors, these methods of “cognitive enhancement” are thought to raise a multitude of ethical issues. This paper presents the six principal ethical issues raised in relation to pharmacological cognitive enhancers (PCEs)—issues such as whether: (1) the medical safety-profile of PCEs justifies restricting or permitting their elective or required use; (2) the enhanced mind can be an “authentic” mind; (3) individuals might be coerced into using PCEs; (4), there is a meaningful distinction to be made between the treatment vs. enhancement effect of the same PCE; (5) unequal access to PCEs would have implications for distributive justice; and (6) PCE use constitutes cheating in competitive contexts. In reviewing the six principal issues, the paper discusses how neuroscientific research might help advance the ethical debate. In particular, the paper presents new arguments about the contribution neuroscience could make to debates about justice, fairness, and cheating, ultimately concluding that neuroscientific research into “personalized enhancement” will be essential if policy is to be truly informed and ethical. We propose an “ethical agenda” for neuroscientific research into PCEs. PMID:24999320

Pharmacological cognitive enhancement-how neuroscientific research could advance ethical debate.

PubMed

Maslen, Hannah; Faulmüller, Nadira; Savulescu, Julian

2014-01-01

THERE ARE NUMEROUS WAYS PEOPLE CAN IMPROVE THEIR COGNITIVE CAPACITIES: good nutrition and regular exercise can produce long-term improvements across many cognitive domains, whilst commonplace stimulants such as coffee temporarily boost levels of alertness and concentration. Effects like these have been well-documented in the medical literature and they raise few (if any) ethical issues. More recently, however, clinical research has shown that the off-label use of some pharmaceuticals can, under certain conditions, have modest cognition-improving effects. Substances such as methylphenidate and modafinil can improve capacities such as working memory and concentration in some healthy individuals. Unlike their more mundane predecessors, these methods of "cognitive enhancement" are thought to raise a multitude of ethical issues. This paper presents the six principal ethical issues raised in relation to pharmacological cognitive enhancers (PCEs)-issues such as whether: (1) the medical safety-profile of PCEs justifies restricting or permitting their elective or required use; (2) the enhanced mind can be an "authentic" mind; (3) individuals might be coerced into using PCEs; (4), there is a meaningful distinction to be made between the treatment vs. enhancement effect of the same PCE; (5) unequal access to PCEs would have implications for distributive justice; and (6) PCE use constitutes cheating in competitive contexts. In reviewing the six principal issues, the paper discusses how neuroscientific research might help advance the ethical debate. In particular, the paper presents new arguments about the contribution neuroscience could make to debates about justice, fairness, and cheating, ultimately concluding that neuroscientific research into "personalized enhancement" will be essential if policy is to be truly informed and ethical. We propose an "ethical agenda" for neuroscientific research into PCEs.

A web-based fact sheet series for grandparents raising grandchildren and the professionals who serve them.

PubMed

Brintnall-Peterson, Mary; Poehlmann, Julie; Morgan, Kari; Shlafer, Rebecca

2009-04-01

To develop and evaluate a series of web-based fact sheets for grandparents raising grandchildren. The fact sheets focus on child development issues that grandparents may face when raising their grandchildren. The fact sheets were developed using research on attachment theory, child development, and the needs of grandparents raising grandchildren. The fact sheets can be viewed online or downloaded for free. Evaluation data for the fact sheets were gathered using an online survey. Results of the survey revealed that the fact sheets are used by grandparents and professionals. Respondents reported sharing the fact sheets with others and using them for personal use, in support groups, and as a general agency resource. The fact sheet series is a useful way to reach both grandparents and professionals working with this audience in a variety of settings. Modifications to the fact sheet series are suggested to address additional needs of grandparents raising grandchildren.

Current Sociopolitical, Sociocultural, and Sociolinguistic Issues of Latino Immigrants in Julia Álvarez's Novel "How the García Girls Lost Their Accents"

ERIC Educational Resources Information Center

Molina-Naar, José

2016-01-01

The sociopolitical, sociocultural, and sociolinguistic issues many Latino immigrants face as they embark on the process of adjusting to American society have been depicted by many Hispanic American writers in the United States. Julia Álvarez's "How the García Girls Lost Their Accents" attempts to raise awareness of these issues through…

Defense Modeling and Simulation Initiative

DTIC Science & Technology

1992-05-01

project solicitation and priority ranking process, and reviewing policy issues . The activities of the DMSO and MSWG are also supported by a series of... issues have been raised for discussion, including: *Proumulgation of standards for the interoperability of models and simulations " Modeling and...have been completed or will be completed in the near term. The policy issues should be defined at a high level in the near term, although their

Teacher and Administrator Training, Recruitment and Retention. INAR/NACIE Joint Issues Sessions National Indian Education Assocation (NIEA) Annual Conference (22nd, San Diego, California, October 15, 1990).

ERIC Educational Resources Information Center

National Advisory Council on Indian Education, Washington, DC.

This report summarizes two joint sessions held by the Indian Nations At Risk Task Force and the National Advisory Council on Indian Education to hear testimony on Native American issues in educator training and employment. Issues and problems related to recruitment of Native Americans into teacher education include raised admission standards, more…

Violent Women: Findings from the Texas Women Inmates Study

ERIC Educational Resources Information Center

Pollock, Joycelyn M.; Mullings, Janet L.; Crouch, Ben M.

2006-01-01

Prior research on violent crime by female offenders is reviewed. A Texas female prisoner sample is used to explore specific questions raised by the literature review. Violent and nonviolent offenders were compared, looking specifically at race, socioeconomic status, having been raised in single-parent homes, criminal history, gang membership,…

7 CFR 305.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... specified temperature for a specific time period to kill targeted pests. Vapor heat. Heated air saturated with water vapor and used to raise the temperature of a commodity to a required point for a specific... products. Hot water immersion dip. Complete immersion of a commodity in heated water to raise the...

Enhancing privacy and data protection in electronic medical environments.

PubMed

Gritzalis, Stefanos

2004-12-01

Raising awareness and providing guidance to on-line data protection is by all means a crucial issue worldwide. Equally important is the issue of applying privacy-related legislation in a coherent and coordinated way. Both these topics become even more critical when referring to medical environments and thus to the protection of patients' privacy and medical data. Electronic medical transactions require the transmission of personal and medical information over insecure communication channels like the Internet. It is therefore a rather straightforward task to construct "patient profiles " that capture the electronic medical behavior of a patient, or even reveal sensitive information in regard with her/his medical history. Clearly, the consequence from maintaining such profiles is the violation of the patient's privacy. This paper studies medical environments that can support electronic medical transactions or/and the provision of medical information through the Web. Specifically it focuses on the countermeasures that the various actor categories can employ for protecting the privacy of personal and medical data transmitted during electronic medical transactions.

Edible insects - defining knowledge gaps in biological and ethical considerations of entomophagy.

PubMed

Pali-Schöll, Isabella; Binder, Regina; Moens, Yves; Polesny, Friedrich; Monsó, Susana

2018-04-25

While seeking novel food sources to feed the increasing population of the globe, several alternatives have been discussed, including algae, fungi or in vitro meat. The increasingly propagated usage of farmed insects for human nutrition raises issues regarding food safety, consumer information and animal protection. In line with law, insects like any other animals must not be reared or manipulated in a way that inflicts unnecessary pain, distress or harm on them. Currently, there is a great need for research in the area of insect welfare, especially regarding species-specific needs, health, farming systems and humane methods of killing. Recent results from neurophysiological, neuroanatomical and behavioral sciences prompt caution when denying consciousness and therefore the likelihood of presence of pain and suffering or something closely related to it to insects. From an animal protection point of view, these issues should be satisfyingly solved before propagating and establishing intensive husbandry systems for insects as a new type of mini-livestock factory farming.

Human cloning and stem cell research: engaging in the political process. (Legislation review: prohibition of Human Cloning Act 2002 and the research involving Human Embryos Act).

PubMed

Skene, Loane

2008-03-01

Committees appointed by governments to inquire into specific policy issues often have no further role when the Committee's report is delivered to government, but that is not always so. This paper describes the activities of members of the Australian Committee on human cloning and embryo research (the Lockhart Committee) to inform Parliament and the community about the Committee's recommendations after its report was tabled in Parliament. It explains their participation in the political process as their recommendations were debated and amending legislation was passed by Parliament. It illustrates a method of communication about scientific and policy issues that explores people's concerns and what they 'need to know' to make a judgment; and then responds to questions they raise, with the aim of facilitating discussion, not arguing for one view. The paper considers whether this type of engagement and communication is appropriate and could be used in other policy discussions.

A comparison of statistical criteria for setting optimally discriminating MCAT and GPA thresholds in medical school admissions.

PubMed

Albanese, Mark A; Farrell, Philip; Dottl, Susan L

2005-01-01

Using Medical College Admission Test-grade point average (MCAT-GPA) scores as a threshold has the potential to address issues raised in recent Supreme Court cases, but it introduces complicated methodological issues for medical school admissions. To assess various statistical indexes to determine optimally discriminating thresholds for MCAT-GPA scores. Entering classes from 1992 through 1998 (N = 752) are used to develop guidelines for cut scores that optimize discrimination between students who pass and do not pass the United States Medical Licensing Examination (USMLE) Step 1 on the first attempt. Risk differences, odds ratios, sensitivity, and specificity discriminated best for setting thresholds. Compensatory versus noncompensatory procedures both accounted for 54% of Step 1 failures, but demanded different performance requirements (noncompensatory MCAT-biological sciences = 8, physical sciences = 7, verbal reasoning = 7--sum of scores = 22; compensatory MCAT total = 24). Rational and defensible intellectual achievement thresholds that are likely to comply with recent Supreme Court decisions can be set from MCAT scores and GPAs.

'Everything is everywhere: but the environment selects': ubiquitous distribution and ecological determinism in microbial biogeography.

PubMed

O'Malley, Maureen A

2008-09-01

Recent discoveries of geographical patterns in microbial distribution are undermining microbiology's exclusively ecological explanations of biogeography and their fundamental assumption that 'everything is everywhere: but the environment selects'. This statement was generally promulgated by Dutch microbiologist Martinus Wilhelm Beijerinck early in the twentieth century and specifically articulated in 1934 by his compatriot, Lourens G. M. Baas Becking. The persistence of this precept throughout twentieth-century microbiology raises a number of issues in relation to its formulation and widespread acceptance. This paper will trace the conceptual history of Beijerinck's claim that 'everything is everywhere' in relation to a more general account of its theoretical, experimental and institutional context. His principle also needs to be situated in relationship to plant and animal biogeography, which, this paper will argue, forms a continuum of thought with microbial biogeography. Finally, a brief overview of the contemporary microbiological research challenging 'everything is everywhere' reveals that philosophical issues from Beijerinck's era of microbiology still provoke intense discussion in twenty-first century investigations of microbial biogeography.

Informed Consent Decision-Making in Deep Brain Stimulation.

PubMed

Mandarelli, Gabriele; Moretti, Germana; Pasquini, Massimo; Nicolò, Giuseppe; Ferracuti, Stefano

2018-05-11

Deep brain stimulation (DBS) has proved useful for several movement disorders (Parkinson’s disease, essential tremor, dystonia), in which first and/or second line pharmacological treatments were inefficacious. Initial evidence of DBS efficacy exists for refractory obsessive-compulsive disorder, treatment-resistant major depressive disorder, and impulse control disorders. Ethical concerns have been raised about the use of an invasive surgical approach involving the central nervous system in patients with possible impairment in cognitive functioning and decision-making capacity. Most of the disorders in which DBS has been used might present with alterations in memory, attention, and executive functioning, which may have an impact on the mental capacity to give informed consent to neurosurgery. Depression, anxiety, and compulsivity are also common in DBS candidate disorders, and could also be associated with an impaired capacity to consent to treatment or clinical research. Despite these issues, there is limited empirical knowledge on the decision-making levels of these patients. The possible informed consent issues of DBS will be discussed by focusing on the specific treatable diseases.

Bibliography of Literature for Avian Issues in Solar and Wind Energy and Other Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walston, Leroy J.; White, Ellen M.; Meyers, Stephanie A.

2015-04-01

Utility-scale solar energy has been a rapidly expanding energy sector in the United States in recent years and is expected to continue to grow. In 2014, concerns were raised over the risk of avian fatalities associated with utility-scale solar plants. With funding from the U.S. Department of Energy SunShot Program, Argonne National Laboratory and the National Renewable Energy Laboratory studied the issue and released A Review of Avian Monitoring and Mitigation Information at Existing Utility-Scale Solar Facilities (ANL/EVS-15/2, March 2015). A comprehensive literature review included peer-reviewed journal articles on avian fatalities from solar energy facilities and other sources (e.g., windmore » energy, building collisions, etc.), project-specific technical reports on avian monitoring and fatality at solar facilities, information on mitigation measures and best management practices, and literature pertaining to avian behavioral patterns and habitat use. The source citations are listed in this bibliography; they are current through December 2014.« less

Disclosure 'downunder': misadventures in Australian genetic privacy law.

PubMed

Bonython, Wendy; Arnold, Bruce

2014-03-01

Along with many jurisdictions, Australia is struggling with the unique issues raised by genetic information in the context of privacy laws and medical ethics. Although the consequences of disclosure of most private information are generally confined to individuals, disclosure of genetic information has far-reaching consequences, with a credible argument that genetic relatives have a right to know about potential medical conditions. In 2006, the Privacy Act was amended to permit disclosure of an individual's genetic information, without their consent, to genetic relatives, if it was to avoid or mitigate serious illness. Unfortunately, additional amendments required for operation of the disclosure amendment were overlooked. Public Interest Determinations (PIDs)-delegated legislation issued by the privacy commissioner-have, instead, been used to exempt healthcare providers from provisions which would otherwise make disclosure unlawful. This paper critiques the PIDs using documents obtained under the Freedom of Information Act-specifically the impact of both the PIDs and the disclosure amendment on patients and relatives-and confidentiality and the procedural validity of subordinate laws regulating medical privacy.

Immigration Policies and Issues on Health-Related Grounds for Exclusion

DTIC Science & Technology

2010-01-29

particularly with its relationship to foreign travel. With Mexico also suffering high infection rates of this strain of influenza, questions have been raised on...particularly with its relationship to foreign travel. With Mexico also suffering high infection rates of this strain of influenza, questions have been raised...meningococcal, pneumococcal, rotavirus, varicella , zoster, and the annual influenza vaccine.36 Most visas denied on this basis are overcome when

Understanding the Needs and Issues of Grandfamilies: A Survey of Grandparents Raising Grandchildren. A Pilot Study.

ERIC Educational Resources Information Center

Racicot, Lina

A recent report from the U.S. Census Bureau revealed that more than five million, or 7%, of U.S. children are being raised in grandparent-headed households. In many of these homes there is no biological parent in residence, and the grandparents have taken over the role of parenting. This family structure has gained enough residence to warrant the…

Spatial Displays and Spatial Instruments

NASA Technical Reports Server (NTRS)

Ellis, Stephen R. (Editor); Kaiser, Mary K. (Editor); Grunwald, Arthur J. (Editor)

1989-01-01

The conference proceedings topics are divided into two main areas: (1) issues of spatial and picture perception raised by graphical electronic displays of spatial information; and (2) design questions raised by the practical experience of designers actually defining new spatial instruments for use in new aircraft and spacecraft. Each topic is considered from both a theoretical and an applied direction. Emphasis is placed on discussion of phenomena and determination of design principles.

Review of Carbonate Breccia Genetic Classification in West Hill, Beijing

NASA Astrophysics Data System (ADS)

Yang, Shuran; Danek, Tomas; Cheng, Xianfeng; Huang, Qianrui

2017-12-01

This thesis proposes genetic classification for carbonate breccia in West Hill, Beijing, summarizes the genesis mechanism and features of 14 types of carbonate breccia there, and raises research questions. Not at all of types were included in this classification, mainly which are not so commonly discussed, such as impact breccia formed by meteorolite. Among other things, it raises the issue of overlapping the concept, which requires further research.

Problematizing the "Taken for Granted" in Educational Issues: Karl Marx, Antonio Gramsci, and Michel Foucault.

ERIC Educational Resources Information Center

Qi, Jie

This paper explores how educators would raise different questions about educational issues by using Karl Marx's framework, Antonio Gramsci's conception, and Michel Foucault's notions, respectively. First, the paper compares the historical perspectives of Marx and Foucault. Marx concludes that history is a progressive linear production and that…

The Bayesian Evaluation of Categorization Models: Comment on Wills and Pothos (2012)

ERIC Educational Resources Information Center

Vanpaemel, Wolf; Lee, Michael D.

2012-01-01

Wills and Pothos (2012) reviewed approaches to evaluating formal models of categorization, raising a series of worthwhile issues, challenges, and goals. Unfortunately, in discussing these issues and proposing solutions, Wills and Pothos (2012) did not consider Bayesian methods in any detail. This means not only that their review excludes a major…

Teacher-Student Sexual Relations: Key Risks and Ethical Issues

ERIC Educational Resources Information Center

Sikes, Pat

2010-01-01

Researching actual or purported sexual contact between teachers and students raises many difficult ethical issues, questions and dilemmas, which may help to explain why few have ventured into the field. This experientially based paper addresses key problem areas under the headings of: the ethics of researching a sensitive taboo topic; the ethics…

49 CFR 190.211 - Hearing.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 3 2012-10-01 2012-10-01 false Hearing. 190.211 Section 190.211 Transportation... PROCEDURES Enforcement § 190.211 Hearing. (a) A request for a hearing provided for in this part must be accompanied by a statement of the issues that the respondent intends to raise at the hearing. The issues may...

What Good Is Soft Evidence?

ERIC Educational Resources Information Center

Murdach, Allison D.

2010-01-01

Along with other helping professions, social work is today struggling to become a more "evidence-based" activity. This article explores some of the issues raised by this reevaluation of social work, especially as it relates to the issue of direct social work practice. Despite the current push to base social work helping methods on scientific…

On Learning to Teach Fat Feminism

ERIC Educational Resources Information Center

Boling, Patricia

2011-01-01

As a feminist theorist who frequently teaches theorizing that starts from embodied experience, the author has begun to incorporate fat feminism into her teaching. As a neophyte and a relatively thin woman, she has been self-conscious about broaching issues related to fat bodies in her teaching, even though they clearly raise important issues about…

Uncovering Student Values for Hiring in the Software Industry

ERIC Educational Resources Information Center

Chinn, Donald; Vandegrift, Tammy

2008-01-01

This article provides an analysis of student responses to an exercise used in a computer ethics and a software engineering course to raise awareness of issues related to hiring, including issues of professional responsibility and diversity. Students from two different universities were asked to evaluate four candidates for two positions in a…

Reading Recovery and ESEA Chapter 1: Issues and Possibilities.

ERIC Educational Resources Information Center

Zajano, Nancy C.

The simultaneous implementation of Reading Recovery (an early intervention program designed to help children "at risk" of failure in their first year of reading instruction) and Chapter 1 programs in schools raises a number of issues as educators attempt to provide effective reading instruction within the policies and guidelines of both…

Assessing Enquiry-Based Learning: Developing Objective Criteria from Personal Knowledge

ERIC Educational Resources Information Center

Small, Tim

2009-01-01

This article takes as its starting point the idea that policies of "personalising learning" and promoting "creativity" raise issues for assessment which the present framework for assessment and testing in schools in England and Wales does little to address. It explores the notion, also touched on elsewhere in this issue, of a…

From Serrano to Serrano. Report No. FA.

ERIC Educational Resources Information Center

Education Commission of the States, Denver, CO. Dept. of Research and Information Services.

This report examines various school finance issues raised by the California case of Serrano v. Priest. Chapter 1 focuses on the issue of local control; it discusses four methods of providing state aid to education in terms of how they affect local control of schools. Chapter 2 analyzes different remedies for inequitable distribution of funds and…

Discipline Identity in Economic History: Reflecting on an Interdisciplinary Community

ERIC Educational Resources Information Center

Shanahan, Martin

2015-01-01

The article by Aileen Fyfe (this issue) raises a number of important issues about academic identity and the importance of the disciplinary community in the creation and maintenance of that identity. It also discusses some of the additional difficulties faced by interdisciplinary disciplines; lack of recognition (and thus institutional support),…

Dialogue: A Teaching Guide to Nuclear Issues.

ERIC Educational Resources Information Center

Educators for Social Responsibility, Cambridge, MA.

Materials in this manual are designed to help educators raise the issue of nuclear war through a "day of dialog" on the subject. There are seven sections. Section 1 contains a project reationale; suggestions for implementation; methods for meeting resistance; tips for schoolwide, parent-teacher, and community discussion; uses of the media; and…

SOCIAL AND EMOTIONAL BEHAVIOR IN INFANCY--SOME DEVELOPMENTAL ISSUES AND PROBLEMS.

ERIC Educational Resources Information Center

RICCIUTI, HENRY N.

INVESTIGATIONS INTO THE NATURE AND DEVELOPMENT OF SOCIAL AND EMOTIONAL BEHAVIOR IN HUMAN INFANCY HAVE RAISED MANY RESEARCH ISSUES AND HAVE INDICATED MANY ADDITIONAL AREAS OF INQUIRY. EARLY AND CONTEMPORARY STUDIES HAVE BOTH BEEN CONCERNED WITH PROVIDING MORE PRECISE ANALYSES OF STIMULUS AND SITUATIONAL DETERMINANTS OF SOCIAL AND EMOTIONAL…

International Epidemiology of Child and Adolescent Psychopathology I: Diagnoses, Dimensions, and Conceptual Issues

ERIC Educational Resources Information Center

Achenbach, Thomas M.; Rescorla, Leslie A.; Ivanova, Masha Y.

2012-01-01

Objectives: To review international findings on the prevalence of diagnosed disorders, generalizability of dimensional scales, and distributions of dimensional scores for school-age children and to address the conceptual and clinical issues raised by the findings. Method: A review of findings for interviews (Development and Well-Being Assessment,…

Human Skill in a Computerized Society: Complex Skills and Their Acquisition.

ERIC Educational Resources Information Center

Lesgold, Alan M.

1986-01-01

This paper discusses some of the issues raised for cognitive psychologists by the computer revolution together with the role that psychologists with computer training ought to play, especially in the study of how people acquire complex skills. The issues addressed include: (1) the competition between humans and intelligent machines; (2) the…

Technology Counts 2009: Breaking Away from Tradition--E-Education Expands Opportunities for Raising Achievement

ERIC Educational Resources Information Center

Education Week, 2009

2009-01-01

This special issue presents the "Education Week's" annual report on education technology, "Technology Counts." This special issue includes the following articles: (1) Breaking Away from Tradition (Michelle R. Davis); (2) Research Shows Evolving Picture of E-Education (Debra Viadero); (3) Advanced Placement Secures Online Niche (Michelle R. Davis);…

Non-Formal Education Implementations in Turkey: Issues and Latest Challenges

ERIC Educational Resources Information Center

Bilir, Mehmet

2007-01-01

The aim of this article is to analyse the latest implementations and issues raised in Turkish non-formal education from a historical perspective in Turkey. The high population rate and lack of adequate educational opportunities for adults and migration from rural areas to urban areas caused many educational, social and cultural problems in…

A Picture Is Worth Less than a Thousand Words: Response to Reviewers.

ERIC Educational Resources Information Center

Motta, Robert W.; And Others

1993-01-01

Responds to reviewers of authors' previous article (Motta, Little, and Tobin, this issue) which reviewed data-based studies on figure drawings and found little support for their validity or use in assessing personality, behavior, emotion, or intellectual functioning. Defends position of original article and addresses issues raised by reviewers.…

Growth Attenuation and Due Process: "A Response to Gunther and Diekema (2006)"

ERIC Educational Resources Information Center

Turnbull, Rud; Wehmeyer, Michael; Turnbull, Ann; Stowe, Matt

2006-01-01

This article presents the authors' response to Gunther and Diekema's argument about growth attenuation and due process. As a case study, growth attenuation raises complicated issues. The authors address some issues that have not been sufficiently addressed. Those involve family support, assistive technology, constitutional rights to "self," the…

Ethical Issues Associated with Client Values Conversion and Therapist Value Agendas in Family Therapy.

ERIC Educational Resources Information Center

Odell, Mark; Stewart, Scott Philip

1993-01-01

Raises ethical concerns inherent in dealing with issue of values in family therapy, focusing on conversion of client values and therapists who may hold evangelistic agendas. Presents brief review of research addressing client values conversion in individual psychotherapy, along with proposed solutions for dealing with values. Offers suggestions…

School Openness, Parent Participation and Satisfaction: An Exploration of Causal Models.

ERIC Educational Resources Information Center

Spivak, Harriet

This case study in policy research was prompted by: (1) concern about a methodological issue: how useful are cross-sectional, non-experimental data for answering policy questions?--and, (2) interest in some policy issues raised by the school decentralization/community control controversies and participatory reforms of the 1960s--are participatory…

Raising Environmental Awareness through Applied Biochemistry Laboratory Experiments

ERIC Educational Resources Information Center

Salman Ashraf, S.

2013-01-01

Our environment is under constant pressure and threat from various sources of pollution. Science students, in particular chemistry students, must not only be made aware of these issues, but also be taught that chemistry (and science) can provide solutions to such real-life issues. To this end, a newly developed biochemistry laboratory experiment…

Employment Protection of School Psychologists: A Cautionary Case

ERIC Educational Resources Information Center

Zirkel, Perry A.

2013-01-01

This article addresses legal issues arising from a district's decision not to renew the employment contract of a 61-year-old school psychologist after 9 years of service. The case focuses on the issues of age discrimination and whistleblowing, although it raises other questions of current relevance to school psychologists, such as the…

Digital Broadband Content: Digital Content Strategies and policies. OECD Digital Economy Papers, No. 119

ERIC Educational Resources Information Center

OECD Publishing (NJ1), 2006

2006-01-01

The development of digital content raises new issues as rapid technological developments challenge existing business models and government policies. This OECD study identifies and discusses six groups of business and public policy issues and illustrates these with existing and potential OECD Digital Content Strategies and Policies: (1) Innovation…

A Short History of Randomized Experiments in Criminology: A Meager Feast.

ERIC Educational Resources Information Center

Farrington, David P.

2003-01-01

Discusses advantages of randomized experiments and key issues raised in this special issue. Focuses on growth and decrease in the use of randomized experiments by the California Youth Authority, the U.S. National Institute of Justice, and the British Home Office. Calls for increased recognition of the importance of randomized experiments. (SLD)

Comorbid Depression and Anxiety in Childhood and Adolescent Anorexia Nervosa: Prevalence and Implications for Outcome

ERIC Educational Resources Information Center

Hughes, Elizabeth K.

2012-01-01

Background: Comorbid conditions are common in individuals with anorexia nervosa (AN) and can raise issues for diagnosis, prognosis, and treatment planning. Methods: First, reported prevalence rates for depression and anxiety in children and adolescents with AN were reviewed. Diagnostic issues and current understanding of the temporal onset and…

Researching Multilingualism and Superdiversity: Grassroots Actions and Responsibilities

ERIC Educational Resources Information Center

Wei, Li

2014-01-01

The articles in this thematic issue document studies of grassroots actions in promoting multilingualism across different sectors of society as well as in different social and professional domains. In doing so, the contributors raise issues of the relevance of the notion of community in the age of superdiversity and the researcher's…

Teaching for Literacy: Reflections on the Bullock Report.

ERIC Educational Resources Information Center

Davis, Frances R. A., Ed.; Parker, Robert P., Jr., Ed.

The 15 articles in this book focus upon the major literacy issues raised by the Bullock Committee in Great Britain and offer reflections upon these issues by United States and British educators who work daily with literacy problems. The articles cover the following topics: the Bullock Committee's work, providing for language growth in young…

Universities Have the Responsibility to Tackle the World's Toughest Problems

ERIC Educational Resources Information Center

Klitgaard, Robert

2008-01-01

Issues that seem intractable not only dominate our news but paralyze our governments. Corruption. Immigration. Religious and cultural conflict. When such issues are raised, too often we roll our eyes and give up before we begin. Using the example of corruption, the author presents ideas for how colleges and universities can help resolve…

Evaluating Assistive Technology in the Education of Persons with Severe Disabilities

ERIC Educational Resources Information Center

Reichle, Joe

2011-01-01

This commentary includes a brief discussion of issues raised by the articles and systematic review contained in this special issue addressing technology applications for persons with severe developmental disabilities. Topical areas include a discussion of: (1) a need to compare "high tech" with "low tech" applications, (2) procedural fidelity, (3)…

78 FR 58240 - International Fisheries; Western and Central Pacific Fisheries for Highly Migratory Species...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-23

... rule. SUMMARY: NMFS issues regulations under authority of the Western and Central Pacific Fisheries... has a legal and moral mandate to reduce bigeye tuna mortality immediately. Response: As stated in the... sections of this final rule, above. The analysis follows: Significant Issues Raised by Public Comments in...

Goldwater-Nichols at 30: Defense Reform and Issues for Congress

DTIC Science & Technology

2016-06-02

observers maintain that a reform of the broader interagency system on national security matters is needed. Despite these disagreements, several...Taken together, however, the issues raised by these questions suggest the systemic nature of the challenges with which the Department of Defense...External Defense Expert Reform Proposals ............................................................................ 24 Formulating Requirements

Ethical Legal and Social Issues of Biobanking: Past, Present, and Future.

PubMed

Bledsoe, Marianna J

2017-04-01

The past 15 years has seen considerable changes in the research environment. These changes include the development of new sophisticated genetic and genomic technologies, a proliferation of databases containing large amount of genotypic and phenotypic data, and wide-spread data sharing among many institutions, nationally and internationally. These changes have raised new questions regarding how best to protect the participants of biobanking research. In response to these questions, best practices for addressing the legal, ethical, and social issues of biobanking have been developed. In addition, new ethical guidelines related to biobanking have been established, as well as new regulations regarding privacy and human subject protections. Finally, changes in the science and the research environment have raised complex ethical issues related to biobanking, such as questions about the most appropriate consent models to use for biobanking research, commercial use and ownership issues, and whether and how to return individual research results to biobank participants. This article reviews some of the developments over the past 15 years related to the ELSI of biobanking with a look toward the future.

Another look at the legal and ethical consequences of pharmacological memory dampening: the case of sexual assault.

PubMed

Chandler, Jennifer A; Mogyoros, Alexandra; Rubio, Tristana Martin; Racine, Eric

2013-01-01

Research on the use of propranolol as a pharmacological memory dampening treatment for post-traumatic stress disorder is continuing and justifies a second look at the legal and ethical issues raised in the past. We summarize the general ethical and legal issues raised in the literature so far, and we select two for in-depth reconsideration. We address the concern that a traumatized witness may be less effective in a prosecution emerging from the traumatic event after memory dampening treatment. We analyze this issue in relation to sexual assault, where the suggestion that corroborating evidence may remedy any memory defects is less likely to be helpful. We also consider the clinical ethical question about a physician's obligation to discuss potential legal consequences of memory dampening treatment. We conclude that this latter question reflects a general problem related to novel medical treatments where the broader socio-legal consequences may be poorly understood, and suggest that issues of this sort could usefully be addressed through the promulgation of practice guidelines. © 2013 American Society of Law, Medicine & Ethics, Inc.

76 FR 4155 - National Emission Standards for Hazardous Air Pollutants for Source Categories: Gasoline...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-24

...This action promulgates amendments to the National Emission Standards for Hazardous Air Pollutants for Source Categories: Gasoline Distribution Bulk Terminals, Bulk Plants, and Pipeline Facilities; and Gasoline Dispensing Facilities, which EPA promulgated on January 10, 2008, and amended on March 7, 2008. In this action, EPA is finalizing amendments and clarifications to certain definitions and applicability provisions of the final rules in response to some of the issues raised in the petitions for reconsideration. In addition, several other compliance-related questions posed by various individual stakeholders and State and local agency representatives are addressed in this action. We are also denying reconsideration on one issue raised in a petition for reconsideration received by the Agency on the final rules.

Ethical issues, dilemmas and controversies in 'cosmetic' or aesthetic dentistry. A personal opinion.

PubMed

Kelleher, M

2012-04-27

Stephen Hancocks' elegant editorial of 11 December 2011 raises interesting questions which deserve discussion. Most experienced dentists would agree that the less that is done to teeth for cosmetic reasons, the lesser are the risks of disappointment, failure of expectation, or threat of litigation. Yet there is an increasing number of cases where aesthetics are the primary concern for dentists and patients alike and some patients are consenting to treatment without being properly informed of the destructive nature of the procedures to their sound tooth tissue and structures to achieve the desired 'cosmetic' outcome. This raises ethical issues, as much of this overtreatment is unnecessarily destructive and goes against the healing and caring principles of the dental profession.

Consideration of the degree of increase in urine metadrenalines provides superior specificity in the diagnosis of phaeochromocytoma than additional urine catecholamine measurement.

PubMed

Scargill, J J; Reed, P; Kane, J

2013-01-01

Measurement of fractionated plasma or urine metadrenalines is the recommended screening test in the diagnosis of phaeochromocytoma, with clinical cut-offs geared towards diagnostic sensitivity. Current practice at Salford Royal Hospital is to add urine catecholamines onto samples with raised urine metadrenalines, with the aim of adding specificity to a diagnosis of phaeochromocytoma. This practice was reviewed by identifying a series of patients with raised urine metadrenalines who had catecholamines reflectively added. A total of 358 samples were identified from 242 patients, of which 228 had urine catecholamines measured. A diagnosis of 'phaeochromocytoma' (n = 41) or 'no phaeochromocytoma' (n = 90) was obtained in 131 of 228 patients, giving raised urine metadrenalines a positive predictive value for phaeochromocytoma of 31%. The finding of increased urine catecholamines in samples with raised urine metadrenalines increased specificity for phaeochromocytoma to 70%. However, 95% diagnostic specificity for phaeochromocytoma could be achieved by the introduction of a second cut-off for urine metadrenalines geared towards maximizing specificity. Consideration of the degree of increase in urine metadrenalines is a superior method of determining the likelihood of phaeochromocytoma than measurement of urine catecholamines.

Validation results of specifications for motion control interoperability

NASA Astrophysics Data System (ADS)

Szabo, Sandor; Proctor, Frederick M.

1997-01-01

The National Institute of Standards and Technology (NIST) is participating in the Department of Energy Technologies Enabling Agile Manufacturing (TEAM) program to establish interface standards for machine tool, robot, and coordinate measuring machine controllers. At NIST, the focus is to validate potential application programming interfaces (APIs) that make it possible to exchange machine controller components with a minimal impact on the rest of the system. This validation is taking place in the enhanced machine controller (EMC) consortium and is in cooperation with users and vendors of motion control equipment. An area of interest is motion control, including closed-loop control of individual axes and coordinated path planning. Initial tests of the motion control APIs are complete. The APIs were implemented on two commercial motion control boards that run on two different machine tools. The results for a baseline set of APIs look promising, but several issues were raised. These include resolving differing approaches in how motions are programmed and defining a standard measurement of performance for motion control. This paper starts with a summary of the process used in developing a set of specifications for motion control interoperability. Next, the EMC architecture and its classification of motion control APIs into two classes, Servo Control and Trajectory Planning, are reviewed. Selected APIs are presented to explain the basic functionality and some of the major issues involved in porting the APIs to other motion controllers. The paper concludes with a summary of the main issues and ways to continue the standards process.

Thermal impact of a small alas-valley river in a continuous permafrost area - insights and issues raised from a field monitoring Site in Syrdakh (Central Yakutia)

NASA Astrophysics Data System (ADS)

Grenier, Christophe; Nicolas, Roux; Fedorov, Alexander; Konstantinov, Pavel; Séjourné, Antoine; Costard, François; Marlin, Christelle; Khristoforov, Ivan; Saintenoy, Albane

2017-04-01

Lakes are probably the most prominent surface water bodies in continuous permafrost areas. As a consequence, they are also the most studied features in these regions (e.g. Fedorov et al. 2014). They are indeed of great interest, not only for local populations that use the water resource they represent both in winter and summer, but also from a climatic point of view as they can be a specific source of green-house gases due to the relatively warmer environment they create, especially associated with their taliks (thawed zone surrounded by permafrost located beneath large enough lakes). From a hydrogeological perspective, such taliks can form complex groundwater networks, thus possibly connecting sub-permafrost groundwater with surface water in the present context of climate change. On the other hand, rivers, another important feature of permafrost landscapes providing similar challenges, have drawn less attention so that only a few studies focus on river interactions with permafrost (e.g. Costard et al. 2014, Grenier et al. 2013). However, the processes of heat transfer at stake between river and permafrost strongly differ from lake systems for several reasons. The geometries differ, the river water flow and thermal regimes and interactions with the lateral slopes (valley) are specific. Of particular importance is the fact that the water, in the case of rivers, is in motion leading to specific heat exchange phenomena between water and soil. (Roux et al., accepted) addressed this issue recently by means of an experimental study in a cold room and associated numerical simulations. The present study focuses on a real river-permafrost system with its full natural complexity. A small alas-valley in the vicinity of Yakutsk (Central Yakutia, Siberia) was chosen. Monitoring was started in October 2012 to study the thermal and hydrological interactions between a river and its underground in this continuous permafrost environment. Thermal sensors were installed inside the river, in the atmosphere and into boreholes in the permafrost, at different locations and various distances from the river and the upstream lake. Hydrological information was collected as well (e.g. water temperature, electrical conductivity, pH and isotopic profiles; river flow rates). Soil properties were studied in pits (e.g. thermal conductivity, soil humidity and temperature measurements). More recently GPR studies were conducted along river profiles complementing the dataset. This new study site is introduced and the major results are presented as well as the main issues raised and future perspectives.

Performable Case Studies in Ethics Education.

PubMed

Robeson, Richard; King, Nancy M P

2017-09-12

Bioethics education often includes the study of short stories, novels, plays, and films, because such materials present case examples that can highlight relevant issues and questions especially vividly for a wide range of students. In addition, creative writing is widely used in the education of health professional students and in continuing education settings for health professionals. There are very few academic or professional disciplines that do not use case studies, but the case study in dialogic form has not been standard practice for thousands of years. Dramatic arts casuistry-the creation and performance of short case studies designed specifically to raise bioethics issues for discussion-represents an application of literature and the medical humanities that is both unique and uniquely valuable. This essay describes the development and history of a course that has been successfully taught to medical students and graduate bioethics students, in which the class researches, writes, and performs a case study designed to elicit reflection and discussion about a topic and set of bioethics issues of current interest to both academic and general audiences. The model is also suited to the presentation and discussion of existing case studies, both live and via on-demand audio.

Performable Case Studies in Ethics Education

PubMed Central

Robeson, Richard; King, Nancy M. P.

2017-01-01

Bioethics education often includes the study of short stories, novels, plays, and films, because such materials present case examples that can highlight relevant issues and questions especially vividly for a wide range of students. In addition, creative writing is widely used in the education of health professional students and in continuing education settings for health professionals. There are very few academic or professional disciplines that do not use case studies, but the case study in dialogic form has not been standard practice for thousands of years. Dramatic arts casuistry—the creation and performance of short case studies designed specifically to raise bioethics issues for discussion—represents an application of literature and the medical humanities that is both unique and uniquely valuable. This essay describes the development and history of a course that has been successfully taught to medical students and graduate bioethics students, in which the class researches, writes, and performs a case study designed to elicit reflection and discussion about a topic and set of bioethics issues of current interest to both academic and general audiences. The model is also suited to the presentation and discussion of existing case studies, both live and via on-demand audio. PMID:28895903

Developing a research agenda on ethical issues related to using social media in healthcare.

PubMed

Adams, Samantha A; Van Veghel, Dennis; Dekker, Lukas

2015-07-01

The consequences of using publicly available social media applications specifically for healthcare purposes are largely unaddressed in current research. Where they are addressed, the focus is primarily on issues of privacy and data protection. We therefore use a case study of the first live Twitter heart operation in the Netherlands, in combination with recent literature on social media from other academic fields, to identify a wide range of ethical issues related to using social media for health-related purposes. Although this case reflects an innovative approach to public education and patient centeredness, it also illustrates the need for institutions to weigh the various aspects of use and to develop a plan to deal with these on a per case basis. Given the continual development of technologies, researchers may not yet be able to oversee and anticipate all of the potential implications. Further development of a research agenda on this topic, the promotion of guidelines and policies, and the publication of case studies that reveal the granularity of individual situations will therefore help raise awareness and assist physicians and institutions in using social media to support existing care services.

Electronic health records, adoption, quality of care, legal and privacy issues and their implementation in emergency departments.

PubMed

Ben-Assuli, Ofir

2015-03-01

Recently, the healthcare sector has shown a growing interest in information technologies. Two popular health IT (HIT) products are the electronic health record (EHR) and health information exchange (HIE) networks. The introduction of these tools is believed to improve care, but has also raised some important questions and legal and privacy issues. The implementation of these systems has not gone smoothly, and still faces some considerable barriers. This article reviews EHR and HIE to address these obstacles, and analyzes the current state of development and adoption in various countries around the world. Moreover, legal and ethical concerns that may be encountered by EHR users and purchasers are reviewed. Finally, links and interrelations between EHR and HIE and several quality of care issues in today's healthcare domain are examined with a focus on EHR and HIE in the emergency department (ED), whose unique characteristics makes it an environment in which the implementation of such technology may be a major contributor to health, but also faces substantial challenges. The paper ends with a discussion of specific policy implications and recommendations based on an examination of the current limitations of these systems. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Evaluation of the patient safety Leadership Walkabout programme of a hospital in Singapore.

PubMed

Lim, Raymond Boon Tar; Ng, Benjamin Boon Lui; Ng, Kok Mun

2014-02-01

The Patient Safety Leadership Walkabout (PSLWA) programme is a commonly employed tool in the West, in which senior leaders visit sites within the hospital that are involved in patient care to talk to healthcare staff about patient safety issues. As there is a lack of perspective regarding PSLWA in Asia, we carried out an evaluation of its effectiveness in improving the patient safety culture in Tan Tock Seng Hospital, Singapore. A mixed methods analysis approach was used to review and evaluate all documents, protocols, meeting minutes, post-walkabout surveys, action plans and verbal feedback pertaining to the walkabouts conducted from January 2005 to October 2012. A total of 321 patient safety issues were identified during the study period. Of these, 308 (96.0%) issues were resolved as of November 2012. Among the various categories of issues raised, issues related to work environment were the most common (45.2%). Of all the issues raised during the walkabouts, 72.9% were not identified through other conventional methods of error detection. With respect to the hospital's patient safety culture, 94.8% of the participants reported an increased awareness in patient safety and 90.2% expressed comfort in openly and honestly discussing patient safety issues. PSLWA serves as a good tool to uncover latent errors before actual harm reaches the patient. If properly implemented, it is an effective method for engaging leadership, identifying patient safety issues, and supporting a culture of patient safety in the hospital setting.

Communication Tools for the Wildland-Urban Interface

Treesearch

Martha C. Monroe

2003-01-01

Effective communication tools can help resource managers address wildland-urban interface issues by reducing conflict, raising awareness, and motivating behavior change among the visitors and residents.

Evaluating the effectiveness of a smoking warning label on raising patient awareness of smoking and bladder cancer.

PubMed

Johnson, B; Abouassaly, R; Ghiculete, D; Stewart, R J

2013-08-01

We assessed the knowledge of patients with regard to the association between smoking and bladder cancer, and examined the impact of a novel smoking warning label on raising awareness of this issue. We conducted a prospective cross-sectional study involving patients who presented to urology and family practice clinics. A questionnaire was used to assess knowledge regarding the association between smoking and various diseases. Participants were also asked to evaluate a novel smoking warning label for bladder cancer. A total of 291 (97%) patients responded to the questionnaire including 143 (95.3%) at urology clinics and 148 (98.7%) at family practice clinics. Overall only 45.2% of respondents were aware of the association between smoking and bladder cancer compared to 97.4% who knew that there was an association between smoking and lung cancer. There were no significant differences in knowledge between those at urology and family practice clinics. After viewing the warning label, 58.1% of respondents stated that it had changed their opinion on smoking and bladder cancer, and 74.8% felt that this label would be an effective tool to raise awareness of the issue. Patients who changed their opinion had statistically significantly less initial knowledge about the association between smoking and bladder cancer (36.7% vs 57.5% for those who did not change their opinion, p <0.001). Awareness of the link between smoking and bladder cancer remains low. The use of a smoking warning label may help raise awareness of this important public health issue. Copyright © 2013 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Current practice and barriers to the management of sexual issues in rheumatology: results of a survey of health professionals.

PubMed

Helland, Y; Garratt, A; Kjeken, I; Kvien, T K; Dagfinrud, H

2013-01-01

To explore multidisciplinary health professionals' (HPs) management of disease-related sexual issues in patients with rheumatic diseases, including their perceptions and assessments, and identify factors that prevent HPs from addressing sexuality as a topic with patients. A self-constructed questionnaire was sent to 647 nurses, physicians, physiotherapists, occupational therapists, social workers, and psychologists working within rheumatology care. A multivariate logistic regression model of significant determinants for initiating sexual topics with patients was built. The mean age of the responders (n = 274, 42% response rate, 87% female) was 46 years. While 96% considered sexuality a relevant topic in rheumatology care, 71% seldom/never raised the topic. The patient was the main initiator (53%), and 88% of HPs gave the patient responsibility to initiate. The HPs with relevant education in sexuality were significantly more comfortable talking about sexuality (p < 0.001) and raised sexual issues significantly more often (p < 0.001). In the multivariate analyses, higher age [odds ratio (OR) 3.69], having relevant education (OR 3.16), and being comfortable to some extent (OR 3.62) or to a large extent (OR 5.58) remained significant predictors to initiating sexual topics. Although HPs regarded sexuality as a relevant topic in rheumatic health care, they seldom raised the topic in consultations. Those with further education in sexuality addressed sexual issues more frequently and felt more comfortable. Correspondingly, the majority of respondents requested more education. Such training should be part of the basic HPs' education, as well as part of postgraduate courses.

Raising Critical Issues in the Analysis of Gender and Science in Children's Literature

ERIC Educational Resources Information Center

Martin, Sonya N.; Siry, Christina A.

2009-01-01

Trevor Owens' paper provides a critique of the role of gender and authority in selected children's books that presented biographies of Albert Einstein and Marie Curie. In the context of discussing Trevor's (2009) article about children's literature, this forum explores issues related to the (a) representation and construction of gender, science,…

Commentary on the OECD's Programme for International Student Assessment (PISA) 2009 Study

ERIC Educational Resources Information Center

Froese-Germain, Bernie

2011-01-01

This paper presents some of the major issues raised in Education International's preliminary analysis of the overall PISA (Programme for International Student Assessment) 2009 study. Some of these issues are: (1) PISA has serious limitations. The study does not cover the full curriculum, focusing on a narrow set of subject areas, neglecting such…

75 FR 77588 - Foreign Futures and Options Contracts on a Non-Narrow-Based Security Index; Commission...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-13

...; information and data relating to the index, including the design, computation and maintenance thereof. In... extension is necessary to address complex or novel issues. The information that a foreign board of trade... 45 days if the foreign security index futures contract raises novel or complex issues that require...

Science as Intellectual Property: Who Controls Research? AAAS Series on Issues in Science and Technology.

ERIC Educational Resources Information Center

Nelkin, Dorothy

The controversial question of who controls research stands at the center of a growing number of legal and administrative disputes which raise critical issues of professional sovereignty, scientific secrecy, and proprietary rights. Although the idea of knowledge as property is not new, the scale and changing nature and structure of contemporary…

California Community Colleges Technology II Strategic Plan, 2000-2005.

ERIC Educational Resources Information Center

California Community Colleges, Sacramento. Office of the Chancellor.

This Strategic Plan aims to address the issues facing California Community Colleges (CCCs) due to new technology. The issues raised by the report include: (1) the pervasive and economically and socially necessary use of the Internet; (2) the digital divide; (3) the need for integrating technology into teaching and learning; (4) the impact of Tidal…

On the Compound Questions Raised by Attempts to Quantify Conversation Analysis' Phenomena, Part I: Introduction.

ERIC Educational Resources Information Center

Weider, D. Lawrence

1993-01-01

Drummond and Hopper's article in this issue, "Back Channels Revisited," is discussed in terms of its ability to elicit contrary responses from different scholars because it incorporates elements of two incommensurate approaches to the study of conversation. Weider sets the stage for subsequent articles in this issue. (11 references) (LB)

Pretending to Play or Playing to Pretend: The Case of Autism

ERIC Educational Resources Information Center

Kasari, Connie; Chang, Ya-Chih; Patterson, Stephanie

2013-01-01

An article by Angeline S. Lillard and others published in the January 2013 issue of "Psychological Bulletin" about the impact of pretend play on child development raised a number of issues about play studies and child psychology. The article claimed that, contrary to current theories on the subject, the evidence of many studies does not…

Relationship of Perinatal PCB Exposure to Neurodevelopmental Outcomes: Reply to Appraisal

ERIC Educational Resources Information Center

Gladen, Beth C.; Rogan, Walter J.

2004-01-01

D.V. Cicchetti, A.S. Kaufman, and S.S. Sparrow (this issue) examine various technical issues related to six studies of perinatal PCB exposure and neurodevelopment and one study of adult PCB exposure and motor function. They raise questions about possible imperfections of the studies, but many of their assertions are unsupported or frankly…

Character Issues: Reality Character Problems and Solutions through Education in Indonesia

ERIC Educational Resources Information Center

Saidek, Abdul Rahim; Islami, Raisul; Abdoludin

2016-01-01

Weak character education raises the problem of corruption, a fight between students, free sex, drugs and rape/abortion indicate that the issue of character education of the nation must be improved and the concern of all parties, the nation's leaders, law enforcement officers, educators, religious leaders, groups and other etc. There are two…

Classroom Assessment in Mathematics: Views from a National Science Foundation Working Conference (Greensboro, North Carolina, May 16-18, 1997).

ERIC Educational Resources Information Center

Bright, George W., Ed.; Joyner, Jeane M., Ed.

This document presents papers from a National Science Foundation (NSF) working conference to identify research issues and implementation strategies that support quality classroom assessment. Papers include: (1) "Understanding and Improving Classroom Assessment: Summary of Issues Raised" (George W. Bright and Jeane M. Joyner); (2) "Recommendations…

Raising the Bar of Teacher Quality: Accountability, Collaboration, and Social Justice. The Claremont Letter. Volume 1, Issue 4

ERIC Educational Resources Information Center

Ganley, DeLacy Derin; Quintanar, Anita P.; Loop, Lisa S.

2006-01-01

Historically, reform efforts to address poor student achievement have focused on a variety of issues other than teacher quality. Movements such as TQM (Total Quality Management), class size reduction (CSR), school leadership, parental involvement, and multicultural curriculum have not directly addressed the power or influence of the individual…

Should All Students Be Required to Take Algebra? Are Any Two Snowflakes Alike?

ERIC Educational Resources Information Center

Morgatto, Sara Festa

2008-01-01

In this article, the author explores the "algebra for all" issue to raise awareness about the many facets of this dilemma facing educators at the middle and high school levels. She discusses both sides of this controversial issue, especially regarding its impact on students' futures relative to higher education and employment. The author concludes…

Implementing a University-Wide Credit-Bearing English Language Enhancement Programme: Issues Emerging from Practice

ERIC Educational Resources Information Center

Fenton-Smith, Ben; Humphreys, Pamela; Walkinshaw, Ian; Michael, Rowan; Lobo, Ana

2017-01-01

Many nations now enrol large numbers of tertiary students with English as an additional language, raising concerns over academic literacy standards. As a result, calls for whole-institution approaches to enhance language proficiency have grown. This paper describes the issues faced by one university that attempted such an approach. We first…

Autonomy as Process and Outcome: Revisiting Cultural and Practical Issues in Motivation for Counseling

ERIC Educational Resources Information Center

Lynch, Martin F.; Vansteenkiste, Maarten; Deci, Edward L.; Ryan, Richard M.

2011-01-01

Three commentators (Carter, 2011; Kim, 2011; Scheel, 2011) concurred with a central proposition of the target article (Ryan, Lynch, Vansteenkiste, & Deci, 2011): that client motivation for counseling is of critical importance to counselors and therapists. In this Reply, we acknowledge and address a number of issues raised by the commentators,…