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Sample records for specific speed centrifugal

  1. Centrifugal pumps: which suction specific speeds are acceptable

    SciTech Connect

    Hallam, J.L.

    1982-04-01

    Suction specific speed is an important consideration when purchasing or analyzing centrifugal pumps. There is a direct correlation between this parameter, pump reliability and maintenance expenses. This article demonstrates that in a large Gulf Coast oil refinery, centrifugal pumps with a suction specific speed greater than 11,000 failed at a frequency nearly twice that of centrifugal pumps with suction specific speed less than 11,000. This study consisted primarily of hydrocarbon pumps with an average horsepower of 150 hp. Results may vary some from those found if high energy water pumps are studied. 5 refs.

  2. TOTAL EFFICIENCY SPECIFIC-SPEED CHARACTERISTICS OF CENTRIFUGAL COMPRESSORS

    NASA Technical Reports Server (NTRS)

    Galvas, M. R.

    1994-01-01

    A computer program has been developed for predicting design point specific speed-efficiency characteristics of centrifugal compressors. Compressor efficiency has been shown to be a function of specific speed. Specific speed is a characteristic that relates compressor inlet volume flow rate, rotation speed, and ideal enthalpy rise. Generally, high efficiencies are associated with high specific speeds, and low efficiencies are associated with low specific speeds. Compressor design point geometries that produce maximum attainable efficiency are also functions of specific speed. Knowing the variation in optimum design point geometric variables with specific speed permits rapid selection of high efficiency configurations. This computer program uses a one-dimensional mean streamline analysis conducted at fixed stagnation conditions. Seven specific losses are calculated for each set of compressor geometric variables and inlet velocity diagram characteristics studied. These are inlet guide vane, blade loading, skin friction, disk friction, recirculation, vaneless diffuser, and vaned diffuser losses. Each of these individual losses is expressed as a decrement in compressor total efficiency. The effect of these losses is then related to overall compressor performance and specific speed. By examining the program output, the user can select values of inducer hub-tip diameter ratio, inducer tip-exit diameter ratio, impeller blade exit backsweep, impeller exit blade height-diameter ratio, and impeller exit absolute flow angle that will result in maximum total efficiency for the chosen application. For given inlet stagnation conditions, the user can generate efficiency, pressure ratio, specific speed, and relative loss distribution data corresponding to various combinations of impeller inlet velocity diagram characteristics and impeller overall geometries. By examining the output data, a compressor geometry can be chosen which will yield maximum efficiency under the constraints

  3. Hydrogen test of a small, low specific speed centrifugal pump stage

    NASA Technical Reports Server (NTRS)

    1991-01-01

    A small, low specific speed centrifugal pump stage with a 2 inch tip diameter, .030 inch tip width shrouded impeller and volute collector was tested with liquid hydrogen as the pumped fluid. The hydrodynamic design of the pump stage is summarized and the noncavitating and cavitating performance results are presented. Test speeds were 60 and 80 percent of the 77,000 rpm design speed. Liquid hydrogen test results are compared with data from previous tests of the stage in water.

  4. FORTRAN program for calculating total efficiency - specific speed characteristics of centrifugal compressors

    NASA Technical Reports Server (NTRS)

    Galvas, M. R.

    1972-01-01

    A computer program for predicting design point specific speed - efficiency characteristics of centrifugal compressors is presented with instructions for its use. The method permits rapid selection of compressor geometry that yields maximum total efficiency for a particular application. A numerical example is included to demonstrate the selection procedure.

  5. Analytical correlation of centrifugal compressor design geometry for maximum efficiency with specific speed

    NASA Technical Reports Server (NTRS)

    Galvas, M. R.

    1972-01-01

    Centrifugal compressor performance was examined analytically to determine optimum geometry for various applications as characterized by specific speed. Seven specific losses were calculated for various combinations of inlet tip-exit diameter ratio, inlet hub-tip diameter ratio, blade exit backsweep, and inlet-tip absolute tangential velocity for solid body prewhirl. The losses considered were inlet guide vane loss, blade loading loss, skin friction loss, recirculation loss, disk friction loss, vaneless diffuser loss, and vaned diffuser loss. Maximum total efficiencies ranged from 0.497 to 0.868 for a specific speed range of 0.257 to 1.346. Curves of rotor exit absolute flow angle, inlet tip-exit diameter ratio, inlet hub-tip diameter ratio, head coefficient and blade exit backsweep are presented over a range of specific speeds for various inducer tip speeds to permit rapid selection of optimum compressor size and shape for a variety of applications.

  6. Unsteady flow characteristic of low-specific-speed centrifugal pump under different flow-rate conditions

    NASA Astrophysics Data System (ADS)

    Cui, Baoling; Chen, Desheng; Xu, Wenjing; Jin, Yingzi; Zhu, Zuchao

    2015-02-01

    To investigate the unsteady flow characteristics in centrifugal pump, the flow field in a low-specific-speed centrifugal pump with complex impeller is numerically simulated under different conditions. The RNG κ-ɛ turbulence model and sliding mesh are adopted during the process of computation. The results show that the interaction between impeller and volute results in the unstable flow of the fluid, which causes the uneven distribution of pressure fluctuations around the circumference of volute. Besides the main frequency and its multiple frequency of pressure fluctuations in the centrifugal pump, the frequency caused by the long blades of complex impeller also plays a dominant role in the low-frequency areas. Furthermore, there exists biggish fluctuation phenomenon near the tongue. The composition of static pressure fluctuations frequency on the volute wall and blade outlet is similar except that the fluctuation amplitude near the volute wall reduces. In general, the different flow rates mainly have influence on the amplitude of fluctuation frequency in the pump, while have little effect on the frequency composition.

  7. SEAL FOR HIGH SPEED CENTRIFUGE

    DOEpatents

    Skarstrom, C.W.

    1957-12-17

    A seal is described for a high speed centrifuge wherein the centrifugal force of rotation acts on the gasket to form a tight seal. The cylindrical rotating bowl of the centrifuge contains a closure member resting on a shoulder in the bowl wall having a lower surface containing bands of gasket material, parallel and adjacent to the cylinder wall. As the centrifuge speed increases, centrifugal force acts on the bands of gasket material forcing them in to a sealing contact against the cylinder wall. This arrangememt forms a simple and effective seal for high speed centrifuges, replacing more costly methods such as welding a closure in place.

  8. The analysis of unsteady characteristics in the low specific speed centrifugal pump with drainage gaps

    NASA Astrophysics Data System (ADS)

    Zhu, B.; Chen, H. X.; Wei, Q.; Zhang, R.

    2012-11-01

    The gap drainage impeller is a new structure of impeller which is based on the idea of flow control, and it has been validated in experiments that this structure can increase the pump efficiency. The purpose of this paper is to explore a valid numerical analysis method for the simulation of low specific speed centrifugal pump, and then investigate the unsteady characteristics of the gap drainage impeller pump. The internal flow numerical simulations were done at multi-flow rates, and the calculated results were analyzed based on comparison with the experimental data of hydraulic performance, pressure pulsation and vibration acceleration. It was confirmed that: the results from the simulation tend to agree well with the experiments; the unsteady method is generally superior to the steady method in computing robustness and prediction accuracy at partial flow rates; the wall friction and clearance leakage should be considered in the performance prediction of the low specific centrifugal pump; the frequency spectra of pressure fluctuation is mainly controlled by the rotor-stator interaction, and the overall energy of pressure fluctuation and vibration is increased in part-load working conditions, especially at large flow rates; the pressure pulsation and the impeller radial fluid force are uneven in circumference, and they propagate in the opposite direction of the shaft rotating; however, the calculation error is considerable when comparing with experiments, and the reasons for which should be researched furthermore.

  9. The optimization of low specific speed centrifugal pump based on incomplete sensitivities

    NASA Astrophysics Data System (ADS)

    Zhang, R. H.; Zheng, K.; Yao, L. H.; Shi, F. X.

    2012-11-01

    In this research, the optimization method for low specific speed centrifugal pump impeller based on incomplete sensitivities was proposed. The main feature of the algorithm is that it avoids solving the flow field repeatedly in one optimization cycle in finite difference method and it avoids solving the adjoint equation in adjoint method. The blade meridional plan is considered as constant, and the blade camber line was parameterize by Taylor function. The coefficients in the Taylor function were taken as the control variable. The moment acting on the blade was considered as the objective function. With the incomplete sensitivities we can get the gradient of the objective function with respect to the control variable easily, and the blade shape can be renewed according to the inverse direction of the gradient. We will find the optimum design when the objective function is minimized. The computational cost is greatly reduced. The calculation cases show that the proposed theory and method is rotational.

  10. Optimization on the impeller of a low-specific-speed centrifugal pump for hydraulic performance improvement

    NASA Astrophysics Data System (ADS)

    Pei, Ji; Wang, Wenjie; Yuan, Shouqi; Zhang, Jinfeng

    2016-09-01

    In order to widen the high-efficiency operating range of a low-specific-speed centrifugal pump, an optimization process for considering efficiencies under 1.0 Q d and 1.4 Q d is proposed. Three parameters, namely, the blade outlet width b 2, blade outlet angle β 2, and blade wrap angle φ, are selected as design variables. Impellers are generated using the optimal Latin hypercube sampling method. The pump efficiencies are calculated using the software CFX 14.5 at two operating points selected as objectives. Surrogate models are also constructed to analyze the relationship between the objectives and the design variables. Finally, the particle swarm optimization algorithm is applied to calculate the surrogate model to determine the best combination of the impeller parameters. The results show that the performance curve predicted by numerical simulation has a good agreement with the experimental results. Compared with the efficiencies of the original impeller, the hydraulic efficiencies of the optimized impeller are increased by 4.18% and 0.62% under 1.0 Q d and 1.4Qd, respectively. The comparison of inner flow between the original pump and optimized one illustrates the improvement of performance. The optimization process can provide a useful reference on performance improvement of other pumps, even on reduction of pressure fluctuations.

  11. Multi-objective optimization of a low specific speed centrifugal pump using an evolutionary algorithm

    NASA Astrophysics Data System (ADS)

    An, Zhao; Zhounian, Lai; Peng, Wu; Linlin, Cao; Dazhuan, Wu

    2016-07-01

    This paper describes the shape optimization of a low specific speed centrifugal pump at the design point. The target pump has already been manually modified on the basis of empirical knowledge. A genetic algorithm (NSGA-II) with certain enhancements is adopted to improve its performance further with respect to two goals. In order to limit the number of design variables without losing geometric information, the impeller is parametrized using the Bézier curve and a B-spline. Numerical simulation based on a Reynolds averaged Navier-Stokes (RANS) turbulent model is done in parallel to evaluate the flow field. A back-propagating neural network is constructed as a surrogate for performance prediction to save computing time, while initial samples are selected according to an orthogonal array. Then global Pareto-optimal solutions are obtained and analysed. The results manifest that unexpected flow structures, such as the secondary flow on the meridian plane, have diminished or vanished in the optimized pump.

  12. Variable-Speed Instrumented Centrifuges

    NASA Technical Reports Server (NTRS)

    Chapman, David K.; Brown, Allan H.

    1991-01-01

    Report describes conceptual pair of centrifuges, speed of which varied to produce range of artificial gravities in zero-gravity environment. Image and data recording and controlled temperature and gravity provided for 12 experiments. Microprocessor-controlled centrifuges include video cameras to record stop-motion images of experiments. Potential applications include studies of effect of gravity on growth and on production of hormones in corn seedlings, experiments with magnetic flotation to separate cells, and electrophoresis to separate large fragments of deoxyribonucleic acid.

  13. Variable-Speed Instrumented Centrifuges

    NASA Technical Reports Server (NTRS)

    Chapman, David K.; Brown, Allan H.

    1991-01-01

    Report describes conceptual pair of centrifuges, speed of which varied to produce range of artificial gravities in zero-gravity environment. Image and data recording and controlled temperature and gravity provided for 12 experiments. Microprocessor-controlled centrifuges include video cameras to record stop-motion images of experiments. Potential applications include studies of effect of gravity on growth and on production of hormones in corn seedlings, experiments with magnetic flotation to separate cells, and electrophoresis to separate large fragments of deoxyribonucleic acid.

  14. Experimental research on internal flow in impeller of a low specific speed centrifugal pump by PIV

    NASA Astrophysics Data System (ADS)

    Zhang, J. F.; Wang, Y. F.; Yuan, S. Q.

    2016-05-01

    For the purpose of investigating the influence of two different impellers, one is with splitter blades and the other one is without splitter blades, on a low-specific centrifugal pump. The experimental investigation in impellers was conducted at different conditions and phases by means of PIV (Particle Image Velocimetry) to study the internal flow. Meanwhile, the absolute and relative velocity distributions in impellers were obtained. Experimental results show that the head value is higher in the impeller with splitter blades and both two head curves appear hump phenomena at small flow rate. The absolute velocity value increases with radius and from pressure side to suction side at the same radius gradually. The splitter blades can scour the wake, making outlet velocity distribution more uniform and improving the internal flow. The velocity distribution becomes less even in the process of closing to tongue due to reinforced interference of tongue on internal flow.

  15. Tip clearance effects on loads and performances of semi-open impeller centrifugal pumps at different specific speeds

    NASA Astrophysics Data System (ADS)

    Boitel, G.; Fedala, D.; Myon, N.

    2016-11-01

    Relevant industrial standards or customer's specifications could strictly forbid any device adjusting the axial rotor/stator position, so that tip clearance between semi-open impeller and casing might become a result of the pump machining tolerances and assembling process, leading to big tip clearance variations compared to its nominal value. Consequently, large disparities of global performances (head, power, efficiency) and axial loads are observed with high risk of both specifications noncompliance and bearing damages. This work aims at quantifying these variations by taking into account tip clearance value and pump specific speed. Computational Fluid Dynamics is used to investigate this phenomenon by means of steady simulations led on a semi-open centrifugal pump numerical model including secondary flows, based on a k-omega SST turbulence model. Four different specific speed pump sizes are simulated (from 8 to 50, SI units), with three tip clearances for each size on a wide flow range (from 40% to 120% of the best efficiency point). The numerical results clearly show that head, power and efficiency increase as the tip clearance decreases for the whole flow range. This effect is more significant when the specific speed is low. Meanwhile, the resulting axial thrust on the impeller is very sensitive to the tip clearance and can even lead to direction inversion.

  16. Experimental study of characteristic curves of centrifugal pumps working as turbines in different specific speeds

    SciTech Connect

    Derakhshan, Shahram; Nourbakhsh, Ahmad

    2008-01-15

    Pump manufacturers do not normally provide the characteristic curves of their pumps working as turbines. Therefore, establishing a correlation between the performances of direct (pump) and reverse (turbine) modes is essential in selecting the proper machine. In this paper, several centrifugal pumps (N{sub s} < 60 (m, m{sup 3}/s)) were tested as turbines. Using experimental data, some relations were derived to predict the best efficiency point of a pump working as a turbine, based on pump hydraulic characteristics. Validity of the presented method was shown using some referenced experimental data. Two equations were presented to estimate the complete characteristic curves of centrifugal pumps as turbines based on their best efficiency point. Deviations of suggested method from experimental data were considered and discussed. Finally, a procedure was presented for selecting a suitable pump to work as a turbine in a small hydro-site. (author)

  17. Secondary Containment Design for a High Speed Centrifuge

    SciTech Connect

    Snyder, K.W.

    1999-03-01

    Secondary containment for high speed rotating machinery, such as a centrifuge, is extremely important for operating personnel safety. Containment techniques can be very costly, ungainly and time consuming to construct. A novel containment concept is introduced which is fabricated out of modular sections of polycarbonate glazed into a Unistrut metal frame. A containment study for a high speed centrifuge is performed which includes the development of parameters for secondary containment design. The Unistrut/polycarbonate shield framing concept is presented including design details and proof testing procedures. The economical fabrication and modularity of the design indicates a usefulness for this shielding system in a wide variety of containment scenarios.

  18. Effect of Speed (Centrifugal Load) on Gear Crack Propagation Direction

    NASA Technical Reports Server (NTRS)

    Lewicki, David G.

    2001-01-01

    The effect of rotational speed (centrifugal force) on gear crack propagation direction was explored. Gears were analyzed using finite element analysis and linear elastic fracture mechanics. The analysis was validated with crack propagation experiments performed in a spur gear fatigue rig. The effects of speed, rim thickness, and initial crack location on gear crack propagation direction were investigated. Crack paths from the finite element method correlated well with those deduced from gear experiments. For the test gear with a backup ratio (rim thickness divided by tooth height) of nib = 0.5, cracks initiating in the tooth fillet propagated to rim fractures when run at a speed of 10,000 rpm and became tooth fractures for speeds slower than 10,000 rpm for both the experiments and anal sis. From additional analysis, speed had little effect on crack propagation direction except when initial crack locations were near the tooth/rim fracture transition point for a given backup ratio. When at that point, higher speeds tended to promote rim fracture while lower speeds (or neglecting centrifugal force) produced tooth fractures.

  19. Experimental characterization of high speed centrifugal compressor aerodynamic forcing functions

    NASA Astrophysics Data System (ADS)

    Gallier, Kirk

    The most common and costly unexpected post-development gas turbine engine reliability issue is blade failure due to High Cycle Fatigue (HCF). HCF in centrifugal compressors is a coupled nonlinear fluid-structure problem for which understanding of the phenomenological root causes is incomplete. The complex physics of this problem provides significant challenges for Computational Fluid Dynamics (CFD) techniques. Furthermore, the available literature fails to address the flow field associated with the diffuser potential field, a primary cause of forced impeller vibration. Because of the serious nature of HCF, the inadequacy of current design approaches to predict HCF, and the fundamental lack of benchmark experiments to advance the design practices, there exists a need to build a database of information specific to the nature of the diffuser generated forcing function as a foundation for understanding flow induced blade vibratory failure. The specific aim of this research is to address the fundamental nature of the unsteady aerodynamic interaction phenomena inherent in high-speed centrifugal compressors wherein the impeller exit flow field is dynamically modulated by the vaned diffuser potential field or shock structure. The understanding of this unsteady aerodynamic interaction is fundamental to characterizing the impeller forcing function. Unsteady static pressure measurement at several radial and circumferential locations in the vaneless space offer a depiction of pressure field radial decay, circumferential variation and temporal fluctuation. These pressure measurements are coupled with high density, full field measurement of the velocity field within the diffuser vaneless space at multiple spanwise positions. The velocity field and unsteady pressure field are shown to be intimately linked. A strong momentum gradient exiting the impeller is shown to extend well across the vaneless space and interact with the diffuser vane leading edge. The deterministic unsteady

  20. Application of a compressible flow solver and barotropic cavitation model for the evaluation of the suction head in a low specific speed centrifugal pump impeller channel

    NASA Astrophysics Data System (ADS)

    Limbach, P.; Müller, T.; Skoda, R.

    2015-12-01

    Commonly, for the simulation of cavitation in centrifugal pumps incompressible flow solvers with VOF kind cavitation models are applied. Since the source/sink terms of the void fraction transport equation are based on simplified bubble dynamics, empirical parameters may need to be adjusted to the particular pump operating point. In the present study a barotropic cavitation model, which is based solely on thermodynamic fluid properties and does not include any empirical parameters, is applied on a single flow channel of a pump impeller in combination with a time-explicit viscous compressible flow solver. The suction head curves (head drop) are compared to the results of an incompressible implicit standard industrial CFD tool and are predicted qualitatively correct by the barotropic model.

  1. NASA Low-Speed Centrifugal Compressor for Fundamental Research

    NASA Technical Reports Server (NTRS)

    Wood, J. R.; Adam, P. W.; Buggele, A. E.

    1983-01-01

    A centrifugal compressor facility being built by the NASA Lewis Research Center is described; its purpose is to obtain benchmark experimental data for internal flow code verification and modeling. The facility will be heavily instrumented with standard pressure and temperature probes and have provisions for flow visualization and laser Doppler velocimetry. The facility will accommodate rotational speeds to 2400 rpm and will be rated at pressures to 1.25 atm. The initial compressor stage for testing is geometrically and dynamically representative of modern high-performance stages with the exception of Mach number levels. Design exit tip speed for the initial stage is 500 ft/sec with a pressure ratio of 1.17. The rotor exit backsweep is 55 deg from radial.

  2. NASA low-speed centrifugal compressor for fundamental research

    NASA Technical Reports Server (NTRS)

    Wood, J. R.; Adam, P. W.; Buggele, A. E.

    1983-01-01

    A new centrifugal compressor facility being built by the NASA Lewis Research Center is described; its purpose is to obtain 'benchmark' experimental data for internal flow code verification and modeling. The facility will be heavily instrumented with standard pressure and temperature probes and have provisions for flow visualization and laser Doppler velocimetry. The facility will accommodate rotational speeds to 2400 rpm and will be rated at pressures to 1.25 atm. The initial compressor stage for testing is geometrically and dynamically representative of modern high-performance stages with the exception of Mach number levels. Design exit tip speed for the initial stage is 500 ft/sec with a pressure ratio of 1.17. The rotor exit backsweep is 55 deg from radial. The facility is expected to be operational in the first half of 1985.

  3. A study on energy saving rate for variable speed condition of multistage centrifugal pump

    NASA Astrophysics Data System (ADS)

    Suh, Sang-Ho; Rakibuzzaman; Kim, Kyung-Wuk; Kim, Hyoung-Ho; Yoon, In Sik; Cho, Min-Tae

    2015-11-01

    Centrifugal pumps are being widely used in many industrial and commercial applications. Many of these pumps are being operated at constant speed but could provide energy savings through adjustable speed operations. The purpose of this study was to get the energy saving rates of the multistage centrifugal pump with variable speed conditions. For this investigation an experimental set up of variable flow and pressure system was made to get energy saving rates and numerical analyses are applied to validate the pump performance. The energy saving and therefore the cost saving depends on the specific duty cycle of which the machine operates. Duty cycle is the proportion of time during which a component, device and system is operated. The duty cycle segmented into different flow rates and weighting the average value for each segment by the interval time. The system was operated at 50% or less of the pump capacity. The input power of the system was carried out by pump characteristics curve of each operating point. The energy consumption was done by the product of specific duty cycle and the input power of the system for constant speed and variable speed drive operation. The total energy consumed for constant speed drive pump was 75,770 kW.hr and for variable speed drive pump was 31,700 kW.hr. The total energy saving of the system was 44,070 kW.hr or 58.16% annually. So, this paper suggests a method of implementing an energy saving on variable-flow and pressure system of the multistage centrifugal pump.

  4. A HIGH SPEED VACUUM CENTRIFUGE SUITABLE FOR THE STUDY OF FILTERABLE VIRUSES

    PubMed Central

    Bauer, Johannes H.; Pickels, Edward G.

    1936-01-01

    1. A high speed centrifuge is described in which the speed is limited only by the strength of the material of which the rotor is made. It carries sixteen tubes, each of which conveniently accommodates 7 cc. of fluid. 2. The centrifuge operates in a very high vacuum and therefore requires only a small amount of driving energy. The arrangement has been found to eliminate the possibility of producing injurious frictional heat. 3. The rotating parts are supported by anair-bearing and are driven by compressed air. 4. The centrifuge has been successfully operated at a speed of 30,000 revolutions per minute, representing a maximum centrifugal force in the fluid of 95,000 times gravity. 5 Celluloid tubes used for centrifugation of fluid at high speeds are described. 6. Experiments are described in which good sedimentation of the yellow fever virus was obtained. PMID:19870550

  5. [The analytical setting of rotary speed of centrifuge rotor and centrifugation time in chemical, biochemical and microbiological practice].

    PubMed

    Zolotarev, K V

    2012-08-01

    The researchers happen to face with suspensions in their chemical, biochemical and microbiological practice. The suspensions are the disperse systems with solid dispersed phase and liquid dispersion medium and with dispersed phase particle size > 100 nm (10-7 m). Quite often the necessity occurs to separate solid particles from liquid. To use for this purpose the precipitation in gravitation field can make the process to progress too long. In this respect an effective mode is the precipitation in the field of centrifugal forces--the centrifugation. The rotary speed of centrifuge rotor and centrifugation time can be set analytically using regularities of general dynamics and hydrodynamics. To this effect, should be written and transformed the equation of First and Second Newton Laws for suspension particle being in the field of centrifugal forces and forces of resistance of liquid and vessel wall. The force of liquid resistance depends on particle motion condition in liquid. To determine the regimen the Archimedes and Reynolds numerical dimensionless criteria are to be applied. The article demonstrates the results of these transformations as analytical inverse ratio dependence of centrifugation time from rotary speed. The calculation of series of "rate-time" data permits to choose the optimal data pair on the assumption of centrifuge capacity and practical reasonability. The results of calculations are validated by actual experimental data hence the physical mathematical apparatus can be considered as effective one. The setting progress depends both from parameter (Reynolds criterion) and data series calculation. So, the most convenient way to apply this operation is the programming approach. The article proposes to use the program Microsoft Excel and VBA programming language for this purpose. The possibility to download the file from Internet to use it for fast solution is proposed.

  6. Centrifugally activated bearing for high-speed rotating machinery

    DOEpatents

    Post, Richard F.

    1994-01-01

    A centrifugally activated bearing is disclosed. The bearing includes an annular member that extends laterally and radially from a central axis. A rotating member that rotates about the central axis relative to the annular member is also included. The rotating member has an interior chamber that surrounds the central axis and in which the annular member is suspended. Furthermore, the interior chamber has a concave shape for retaining a lubricant therein while the rotating member is at rest and for retaining a lubricant therein while the rotating member is rotating. The concave shape is such that while the rotating member is rotating a centrifugal force causes a lubricant to be forced away from the central axis to form a cylindrical surface having an axis collinear with the central axis. This centrifugally displaced lubricant provides restoring forces to counteract lateral displacement during operation.

  7. Centrifugally activated bearing for high-speed rotating machinery

    DOEpatents

    Post, R.F.

    1994-02-15

    A centrifugally activated bearing is disclosed. The bearing includes an annular member that extends laterally and radially from a central axis. A rotating member that rotates about the central axis relative to the annular member is also included. The rotating member has an interior chamber that surrounds the central axis and in which the annular member is suspended. Furthermore, the interior chamber has a concave shape for retaining a lubricant therein while the rotating member is at rest and for retaining a lubricant therein while the rotating member is rotating. The concave shape is such that while the rotating member is rotating a centrifugal force causes a lubricant to be forced away from the central axis to form a cylindrical surface having an axis collinear with the central axis. This centrifugally displaced lubricant provides restoring forces to counteract lateral displacement during operation. 4 figures.

  8. CENTRIFUGE

    DOEpatents

    Rushing, F.C.

    1960-09-01

    A vibration damping mechanism for damping vibration forces occurring during the operation of a centrifuge is described. The vibration damping mechanism comprises a plurality of nested spaced cylindrical elements surrounding the rotating shaft of the centrifuge. Some of the elements are held substantially stationary while the others are held with respect to a pair of hearings spaced along the rotating shaft. A fluid is retained about the cylindrical elements.

  9. The Haemonetics Cell Saver 5 washing properties: effect of different washing pump and centrifuge speeds.

    PubMed

    Naumenko, Konstantin S; Kim, Sergey F; Cherkanova, Marina S; Naumenko, Sergey E

    2008-10-01

    This study evaluated the effect of different washing and centrifuge rates of the Cell Saver 5 on the quality of processed autologous blood. Autologous blood was washed with 1000 ml of sterile normal saline at centrifuge speed of 5650 revolutions per minute (rpm) (group I) or 4350 rpm (group II) with different washing pump speeds--500, 800 and 1000 ml/min. Hemoglobin, free hemoglobin, hematocrit, erythrocytes, leukocytes, platelets, and protein were measured before and after processing. The highest values of hemoglobin, hematocrit and erythrocytes were achieved using 800 and 1000 ml/min pump speeds in group I and 500 ml/min speed in group II. Red blood cells concentration was higher in group I. There were no significant changes of free hemoglobin removal within group I. In group II the lowest free hemoglobin was achieved when 1000 ml/min rate was used. Platelets and protein did not depend on wash pump speeds in both groups. Platelet recovery in group I was higher than in group II at all washing pump speeds. Leukocytes were not adequately removed at all pump speeds. The Cell Saver 5 produces optimum results when the high wash pump speeds (800 and 1000 ml/min) and standard centrifuge speed are used.

  10. Dense and Homogeneous Compaction of Fine Ceramic and Metallic Powders: High-Speed Centrifugal Compaction Process

    SciTech Connect

    Suzuki, Hiroyuki Y.

    2008-02-15

    High-Speed Centrifugal Compaction Process (HCP) is a variation of colloidal compacting method, in which the powders sediment under huge centrifugal force. Compacting mechanism of HCP differs from conventional colloidal process such as slip casting. The unique compacting mechanism of HCP leads to a number of characteristics such as a higher compacting speed, wide applicability for net shape formation, flawless microstructure of the green compacts, etc. However, HCP also has several deteriorative characteristics that must be overcome to fully realize this process' full potential.

  11. Inference of optimal speed for sound centrifugal casting of Al-12Si alloys

    NASA Astrophysics Data System (ADS)

    Agari, Shailesh Rao; Mukunda, P. G.; Rao, Shrikantha S.; Sudhakar, K. G.

    2011-05-01

    True centrifugal casting is a standard casting technique for the manufacture of hollow, intricate and sound castings without the use of cores. The molten metal or alloy poured into the rotating mold forms a hollow casting as the centrifugal forces lift the liquid along the mold inner surface. When a mold is rotated at low and very high speeds defects are found in the final castings. Obtaining the critical speed for sound castings should not be a matter of guess or based on experience. The defects in the casting are mainly due to the behavior of the molten metal during the teeming and solidification process. Motion of molten metal at various speeds and its effect during casting are addressed in this paper. Eutectic Al-12Si alloy is taken as an experiment fluid and its performance during various rotational speeds is discussed.

  12. Specific Yield--Column drainage and centrifuge moisture content

    USGS Publications Warehouse

    Johnson, A.I.; Prill, R.C.; Morris, D.A.

    1963-01-01

    The specific yield of a rock or soil, with respect to water, is the ratio of (1) the volume of water which, after being saturated, it will yield by gravity to (2) its own volume. Specific retention represents the water retained against gravity drainage. The specific yield and retention when added together are equal to the total interconnected porosity of the rock or soil. Because specific retention is more easily determined than specific yield, most methods for obtaining yield first require the determination of specific retention. Recognizing the great need for developing improved methods of determining the specific yield of water-bearing materials, the U.S. Geological Survey and the California Department of Water Resources initiated a cooperative investigation of this subject. The major objectives of this research are (1) to review pertinent literature on specific yield and related subjects, (2) to increase basic knowledge of specific yield and rate of drainage and to determine the most practical methods of obtaining them, (3) to compare and to attempt to correlate the principal laboratory and field methods now commonly used to obtain specific yield, and (4) to obtain improved estimates of specific yield of water-bearing deposits in California. An open-file report, 'Specific yield of porous media, an annotated bibliography,' by A. I. Johnson, D. A. Morris, and R. C. Prill, was released in 1960 in partial fulfillment of the first objective. This report describes the second phase of the specific-yield study by the U.S. Geological Survey Hydrologic Laboratory at Denver, Colo. Laboratory research on column drainage and centrifuge moisture equivalent, two methods for estimating specific retention of porous media, is summarized. In the column-drainage study, a wide variety of materials was packed into plastic columns of 1- to 8-inch diameter, wetted with Denver tap water, and drained under controlled conditions of temperature and humidity. The effects of cleaning the

  13. Experimental and computational results from a large low-speed centrifugal impeller

    NASA Technical Reports Server (NTRS)

    Hathaway, M. D.; Chriss, R. M.; Wood, J. R.; Strazisar, A. J.

    1993-01-01

    An experimental and computational investigation of the NASA Low-Speed Centrifugal Compressor (LSCC) flow field has been conducted using laser anemometry and Dawes' 3D viscous code. The experimental configuration consists of a backswept impeller followed by a vaneless diffuser. Measurements of the three-dimensional velocity field were acquired at several measurement planes through the compressor. The measurements describe both the throughflow and secondary velocity field along each measurement plane and in several cases provide details of the flow within the blade boundary layers. The experimental and computational results provide a clear understanding of the development of the throughflow momentum wake which is characteristic of centrifugal compressors.

  14. Evaluating the role of low-speed centrifugation towards transfecting human peripheral blood mononuclear cell culture.

    PubMed

    Majumdar, M; Ratho, R; Chawla, Y; Singh, M P

    2014-01-01

    The conventional method of transfection of suspension cells by chemical has proven to be very difficult. We present a new transfection protocol, wherein, low-speed centrifugation of cell culture plates immediately after adding the lipid: DNA complex significantly enhances the transfection efficiency. Peripheral blood mononuclear cells (PBMCs) were transfected with BLOCK-iT™ Fluorescent Oligo (scrambled siRNA) and lipofectamine complex using conventional and low-speed centrifugation modified transfection protocols. The efficiency of transfection was determined using flowcytometer and cell viability was checked using MTT assay. Incorporation of low-speed centrifugation significantly enhances the transfection efficiency of BLOCK-iT™ in the suspension culture of PBMCs as compared to conventional transfection method (99.8% vs 28.3%; P < 0.0001), even at a low concentration of 40 picomoles without affecting the cell viability. Centrifugation enhanced transfection (CET) technique is simple, time-saving and novel application without compromising the cell viability in the context of recently popular RNA interference in suspension cultures of PBMCs. This undemanding modification might be applicable to a wide variety of cell lines and solve crucial problem of researchers working with RNA interference in suspension cultures.

  15. Lipaemic samples: effective process for lipid reduction using high speed centrifugation compared with ultracentrifugation.

    PubMed

    Dimeski, Goce; Jones, Brock W

    2011-01-01

    Reducing laboratory errors and improving patient safety is receiving a lot of attention. Lipaemic samples are cause of analytical errors and present challenges for laboratories, particularly for those without ultracentrifuges. Lipaemia can originate from physiological (postprandial metabolism), para-physiological causes (e.g. IV administration of lipids) as well as metabolic disturbances (e.g. hypertriglyceridaemia). We have evaluated a procedure with 10 native lipaemic sample pools (triglyceride concentration range 11.6-42.7 mmol/L) for the ability to reduce lipid concentration using a high speed micro-centrifuge (double centrifuged at 21.885 x g for 15 min) compared with an ultracentrifuge, and provide accurate results. Results of sodium, creatinine, urate, total protein, lactate dehydrogenase (LD), magnesium and, cholesterol and triglyceride analysis on a Beckman DxC800 analyser are presented. Data from our tertiary level hospital showed approximately 0.7% of the samples received for lipid studies have triglyceride levels > 10 mmol/L which can potentially cause analytical interference. The mean differences from the neat aliquot to the ultracentrifuged and high speed centrifuged sample pools were: cholesterol 4.9 mmol/L and 3.1 mmol/L; and triglycerides 17.4 mmol/L and 15.0 mmol/L respectively. The data confirms high speed centrifugation is almost as effective as ultracentrifugation in lipid reduction. The procedure utilized in this study using a high speed micro-centrifuge showed it is effective in reducing lipid levels and provides a suitable alternative to ultracentrifuged samples to provide accurate results.

  16. Chemical characteristics of low-fat soymilk prepared by low-speed centrifugal fractionation of the raw soymilk.

    PubMed

    Liu, Zhi-Sheng; Chang, Sam K C

    2010-06-01

    Large oil-protein particles (2 to 60 microm) were found in raw soymilk (or water extract of soybean), which was prepared in specific conditions. The large particles could be separated by sedimentation by centrifuging raw soymilk for 5 to 30 min at a low gravitational force ranging from 96 to 2410 x g. Chemical analysis showed that 80% to 90% of the total lipids and 30% to 40% of the total proteins were located in the precipitated fraction. The supernatant fraction had a dramatically higher protein-to-lipid ratio than the whole soymilk. The ratio of 11S/7S proteins and the ratio of 11S acidic/basic subunits were significantly (P < 0.05) higher in the precipitate than that either in the whole soymilk or in the supernatant. Besides centrifuging conditions, other factors, including soymilk concentration, grinding method, soybean variety, and soybean storage, also significantly (P < 0.05) affected the centrifugal fractionation. This study showed that low-speed centrifugation facilitated the separation of oil-protein particles from raw soymilk, and can be used as an innovative method for preparing low-fat soymilk and 11S protein-enriched ingredients. The findings also increased our understanding of the association or aggregation between proteins and lipids in raw soymilk after grinding.

  17. Review of the gas centrifuge until 1962. Part II: Principles of high-speed rotation

    NASA Astrophysics Data System (ADS)

    Whitley, Stanley

    1984-01-01

    The principles of the separation physics of the gas centrifuge were described in Part I of this review. In this second section the principles involved in spinning the rotors of these centrifuges are described. Three types of rotor can be identified, depending on the ratio of length to diameter. If the rotor is very short, length-diameter ratio less than one, it is gyroscopically stable and easy to spin. If the length-diameter ratio is in the region of 4 or 5, the rotor behaves as a rigid body and is relatively easy to accelerate to speed; however, it has a tendency at full speed to exhibit gyroscopic precessions. Finally, if the length-diameter ratio is very large, the rotor becomes easy to stabilize gyroscopically, but it is difficult to get it to speed because long rotors are very flexible and have resonant frequencies of flexure lower than the operating speed. The problems of these three types of centrifuge (the rotor dynamics, the bearings used to support the rotor, and the stress analysis of the rotating components) were investigated in the last century as part of classical mechanics because of the emergence of steam turbines during the latter part of the industrial revolution. These early principles are briefly reviewed, with particular reference to the work of De Laval, who invented the principle of self-balancing, Reynolds and Evershed, who developed hydrodynamic and magnetic bearing, respectively, and Chree, who did the most extensive early work on the stress analysis of tubes and discs. The work is described as it applies to the centrifuges developed in America and Germany during the war and in the Soviet Union after the war. The work of Beams in America is described in most detail, since he and his colleagues developed all three types of centrifuge during the Manhattan Project. The other work described is that of Groth and Beyerle, who developed subcritical machines in Germany during the war, and of Steenbeck and Zippe, who helped to develop both

  18. CENTRIFUGE APPARATUS

    DOEpatents

    Skarstrom, C.; Urey, H.C.; Cohen, K.

    1960-08-01

    A high-speed centrifuge for the separation of gaseous isotopes is designed comprising a centrifugal pump mounted on the outlet of a centrifuge bowl and arranged to pump the heavy and light fractions out of the centrifuge bowl in two separate streams.

  19. CENTRIFUGES

    DOEpatents

    Beams, J.W.; Snoddy, L.B.

    1960-08-01

    Damping bearings for use on the shafts of an ultracentrifuge were designed which are capable of passing through critical angular speeds. The shaft extending from one end of the rotor is journaled in fixed-plain bearings mounted on annular resilient shock-absorbing elements to dampen small vibrations. The shaft at the other end of the rotor is journaled in two damper-bearing assemblies which are so spaced on the shaft that a vibration node can at no time exist at both bearing assemblies. These bearings are similar to the other bearings except that the bearing housings are slidably mounted on the supporting structure for movement transverse to the rotational axis of the rotor.

  20. Critical cavitation coefficient analysis of a space low specific centrifugal pump with micro gravity

    NASA Astrophysics Data System (ADS)

    Liu, J. T.; Li, Y.; Gao, Y.; Hu, Q.; Zhou, C.; Wu, Y. L.

    2016-05-01

    Centrifugal pump was used in the loop as a baselined unit. The flow rate of the pump was very small, while the head was high. This space pump must work stable for a long time (more than a year), so the performance of the pump attracted public attention. The rotational speed of the impeller was limited for stability, so the pump belonged to low specific centrifugal pump. In this paper, a single-phase centrifugal pump, which was designed for single-phase fluid loops in satellites, was modeled for numerical simulation. The hydraulic region of the pump was discretized by structured mesh. Three dimensional (3-D) flow in the pump was studied by the use of computational fluid dynamics. Partially-Averaged Navier- Stokes (PANS) model based on RNG k-ε turbulence model was developed for the simulation of the unsteady flow. Velocity inlet and pressure outlet was used as the boundary conditions. Interface was used between the impeller and the casing, as well as the impeller and inlet pipe. Performances and pressure fluctuation of the pump were investigated. The dominant frequency of the pressure fluctuation is blade passing frequency at the region close to the tongue of the casing, while it is twice of blade passing frequency at the other region.

  1. Experimental and computational investigation of the NASA low-speed centrifugal compressor flow field

    NASA Technical Reports Server (NTRS)

    Hathaway, Michael D.; Chriss, Randall M.; Wood, Jerry R.; Strazisar, Anthony J.

    1993-01-01

    An experimental and computational investigation of the NASA Lewis Research Center's low-speed centrifugal compressor (LSCC) flow field was conducted using laser anemometry and Dawes' three-dimensional viscous code. The experimental configuration consisted of a backswept impeller followed by a vaneless diffuser. Measurements of the three-dimensional velocity field were acquired at several measurement planes through the compressor. The measurements describe both the throughflow and secondary velocity field along each measurement plane. In several cases the measurements provide details of the flow within the blade boundary layers. Insight into the complex flow physics within centrifugal compressors is provided by the computational fluid dynamics analysis (CFD), and assessment of the CFD predictions is provided by comparison with the measurements. Five-hole probe and hot-wire surveys at the inlet and exit to the impeller as well as surface flow visualization along the impeller blade surfaces provided independent confirmation of the laser measurement technique. The results clearly document the development of the throughflow velocity wake that is characteristic of unshrouded centrifugal compressors.

  2. Quality evaluation of energy consumed in flow regulation method by speed variation in centrifugal pumps

    NASA Astrophysics Data System (ADS)

    Morales, S.; Culman, M.; Acevedo, C.; Rey, C.

    2014-06-01

    Nowadays, energy efficiency and the Electric Power Quality are two inseparable issues in the evaluation of three-phase induction motors, framed within the program of Rational and Efficient Use of Energy (RUE).The use of efficient energy saving devices has been increasing significantly in RUE programs, for example the use of variable frequency drives (VFD) in pumping systems.The overall objective of the project was to evaluate the impact on power quality and energy efficiency in a centrifugal pump driven by an induction three-phase motor, using the flow control method of speed variation by VFD. The fundamental purpose was to test the opinions continuously heard about the use of flow control methods in centrifugal pumps, analyzing the advantages and disadvantages that have been formulated deliberately in order to offer support to the industry in taking correct decisions. The VFD changes the speed of the motor-pump system increasing efficiency compared to the classical methods of regulation. However, the VFD originates conditions that degrade the quality of the electric power supplied to the system and therefore its efficiency, due to the nonlinearity and presence of harmonic currents. It was possible to analyze the power quality, ensuring that the information that comes to the industry is generally biased.

  3. [Technical consideration of setting up a specification for human centrifuge evaluation of anti-G equipment].

    PubMed

    Zhang, C L; Geng, X C; Zhang, W X; Yan, G D; Chu, X

    1999-12-01

    Anti-G equipment needs to be evaluated using human centrifuge before further developed. However, there isn't a general specification for human centrifuge evaluation of anti-G equipment. From related literature and from our over thirty years experience in this area, we sum up to five aspect technical consideration below: human centrifuge, medical specification for using human in +Gz stress experiment, anti-G equipment experimental assembly, principle should be abided by during human centrifuge evaluation of anti-G equipment. We hope that the technical considerations mentioned in the paper should be helpful to the work of setting up a specification for human centrifuge evaluation anti-G equipment. After we have a specification, the research will be conducted orderly and the anti-G [correction of an-G] equipment will be developed sequentially.

  4. In-Situ Observation of Horizontal Centrifugal Casting using a High-Speed Camera

    NASA Astrophysics Data System (ADS)

    Esaka, Hisao; Kawai, Kohsuke; Kaneko, Hiroshi; Shinozuka, Kei

    2012-07-01

    In order to understand the solidification process of horizontal centrifugal casting, experimental equipment for in-situ observation using transparent organic substance has been constructed. Succinonitrile-1 mass% water alloy was filled in the round glass cell and the glass cell was completely sealed. To observe the movement of equiaxed grains more clearly and to understand the effect of movement of free surface, a high-speed camera has been installed on the equipment. The most advantageous point of this equipment is that the camera rotates with mold, so that one can observe the same location of the glass cell. Because the recording rate could be increased up to 250 frames per second, the quality of movie was dramatically modified and this made easier and more precise to pursue the certain equiaxed grain. The amplitude of oscillation of equiaxed grain ( = At) decreased as the solidification proceeded.

  5. High Speed Stereovision Setup for Position and Motion Estimation of Fertilizer Particles Leaving a Centrifugal Spreader

    PubMed Central

    Hijazi, Bilal; Cool, Simon; Vangeyte, Jürgen; Mertens, Koen C.; Cointault, Frédéric; Paindavoine, Michel; Pieters, Jan G.

    2014-01-01

    A 3D imaging technique using a high speed binocular stereovision system was developed in combination with corresponding image processing algorithms for accurate determination of the parameters of particles leaving the spinning disks of centrifugal fertilizer spreaders. Validation of the stereo-matching algorithm using a virtual 3D stereovision simulator indicated an error of less than 2 pixels for 90% of the particles. The setup was validated using the cylindrical spread pattern of an experimental spreader. A 2D correlation coefficient of 90% and a Relative Error of 27% was found between the experimental results and the (simulated) spread pattern obtained with the developed setup. In combination with a ballistic flight model, the developed image acquisition and processing algorithms can enable fast determination and evaluation of the spread pattern which can be used as a tool for spreader design and precise machine calibration. PMID:25401688

  6. Digital PIV Measurements in the Diffuser of a High Speed Centrifugal Compressor

    NASA Technical Reports Server (NTRS)

    Wernet, Mark P.

    1998-01-01

    Particle Imaging Velocimetry (PIV) is a powerful measurement technique which can be used as an alternative or complementary approach to Laser Doppler Velocimetry (LDV) in a wide range of research applications. PIV data are measured simultaneously at multiple points in space, which enables the investigation of the non-stationary spatial structures typically encountered in turbomachinery. Obtaining ample optical access, sufficiently high seed particle concentrations and accurate synchronization of image acquisition relative to impeller position are the most formidable tasks in the successful implementation of PIV in turbomachinery. Preliminary results from the successful application of the standard 2-D digital PIV technique in the diffuser of a high speed centrifugal compressor are presented. Instantaneous flow. measurements were also obtained during compressor surge.

  7. High speed stereovision setup for position and motion estimation of fertilizer particles leaving a centrifugal spreader.

    PubMed

    Hijazi, Bilal; Cool, Simon; Vangeyte, Jürgen; Mertens, Koen C; Cointault, Frédéric; Paindavoine, Michel; Pieters, Jan G

    2014-11-13

    A 3D imaging technique using a high speed binocular stereovision system was developed in combination with corresponding image processing algorithms for accurate determination of the parameters of particles leaving the spinning disks of centrifugal fertilizer spreaders. Validation of the stereo-matching algorithm using a virtual 3D stereovision simulator indicated an error of less than 2 pixels for 90% of the particles. The setup was validated using the cylindrical spread pattern of an experimental spreader. A 2D correlation coefficient of 90% and a Relative Error of 27% was found between the experimental results and the (simulated) spread pattern obtained with the developed setup. In combination with a ballistic flight model, the developed image acquisition and processing algorithms can enable fast determination and evaluation of the spread pattern which can be used as a tool for spreader design and precise machine calibration.

  8. An Investigation of Surge in a High-Speed Centrifugal Compressor Using Digital PIV

    NASA Technical Reports Server (NTRS)

    Wernet, Mark P.; Bright, Michelle M.; Skoch, Gary J.

    2002-01-01

    Compressor stall is a catastrophic breakdown of the flow in a compressor, which can lead to a loss of engine power, large pressure transients in the inlet/nacelle and engine flameout. The implementation of active or passive strategies for controlling rotating stall and surge can significantly extend the stable operating range of a compressor without substantially sacrificing performance. It is crucial to identify the dynamic changes occurring in the flow field prior to rotating stall and surge in order to successfully control these events. Generally, pressure transducer measurements are made to capture the transient response of a compressor prior to rotating stall. In this investigation, Digital Particle Imaging Velocimetry (DPIV) is used in conjunction with dynamic pressure transducers to simultaneously capture transient velocity and pressure measurements in the non-stationary flow field during compressor surge. DPIV is an instantaneous, planar measurement technique which is ideally suited for studying transient flow phenomena in high speed turbomachinery and has been used previously to successfully map the stable operating point flow field in the diffuser of a high speed centrifugal compressor. Through the acquisition of both DPIV images and transient pressure data, the time evolution of the unsteady flow during surge is revealed.

  9. Compound planetary hydro-mechanical transmission with speed-responsive centrifugal clutch means

    SciTech Connect

    Smith, R.R.

    1986-02-04

    This patent describes a power transmission consisting of a first sun gear constituting a first drive, a ring gear constituting a driven output, a number of first non-orbiting planet gears arranged between the first sun gear and ring gear to constitute a first driving connection. A second sun gear constitutes a second drive, the second sun gear having a different rotation axis than the first sun gear. A number of second non-orbiting planet gears individually are rotatable on the same axis as the first planet gears. The second planet gears are meshed with the second sun gear to be driven. Each of the second planet gears have a different diameter whereby each second planet gear has a different rotational speed. Each also has a centrifugal clutch arranged between each of the first planet gears and the associated second planet gear. When each first planet gear attains a predetermined rotational speed, a second driving connection is established from each second planet gear to the associated first planet gear.

  10. The effect of centrifugation speeds of 11,000 g and 13,000 g on small salivary protein profiles (less than 30 kDa)

    NASA Astrophysics Data System (ADS)

    Nugraha, R. A.; Baskoro, B. D.; Puspitawati, R.; Redjeki, S.

    2017-08-01

    Previous research suggested that centrifugation is not necessary to see proteins <30 kDa. There is no standard procedure for regulating the centrifugation speed to separate proteins <30 kDa. The aim of this study is too determine the effect of centrifugation speeds of 11,000 g and 13,000 g on separating salivary supernatant proteins <30 kDa. After being centrifuged at 11,000 g and 13,000 g, the salivary protein profile was tested using SDS-PAGE. The frequency of salivary supernatant protein occurrence (after being centrifuged at 11,000 g and 13,000 g) were 35 and 45 with ranges of 9-27 kDa and 8-18 kDa respectively. Compared to 11,000 g, the centrifugation speed of 13,000 g separates more proteins <30 kDa with a narrower range.

  11. Optical Flow-Field Techniques Used for Measurements in High-Speed Centrifugal Compressors

    NASA Technical Reports Server (NTRS)

    Skoch, Gary J.

    1999-01-01

    The overall performance of a centrifugal compressor depends on the performance of the impeller and diffuser as well as on the interactions occurring between these components. Accurate measurements of the flow fields in each component are needed to develop computational models that can be used in compressor design codes. These measurements must be made simultaneously over an area that covers both components so that researchers can understand the interactions occurring between the two components. Optical measurement techniques are being used at the NASA Lewis Research Center to measure the velocity fields present in both the impeller and diffuser of a 4:1 pressure ratio centrifugal compressor operating at several conditions ranging from design flow to surge. Laser Doppler Velocimetry (LDV) was used to measure the intrablade flows present in the impeller, and the results were compared with analyses obtained from two three-dimensional viscous codes. The development of a region of low throughflow velocity fluid within this high-speed impeller was examined and compared with a similar region first observed in a large low-speed centrifugal impeller at Lewis. Particle Image Velocimetry (PIV) is a relatively new technique that has been applied to measuring the diffuser flow fields. PIV can collect data rapidly in the diffuser while avoiding the light-reflection problems that are often encountered when LDV is used. The Particle Image Velocimeter employs a sheet of pulsed laser light that is introduced into the diffuser in a quasi-radial direction through an optical probe inserted near the diffuser discharge. The light sheet is positioned such that its centerline is parallel to the hub and shroud surfaces and such that it is parallel to the diffuser vane, thereby avoiding reflections from the solid surfaces. Seed particles small enough to follow the diffuser flow are introduced into the compressor at an upstream location. A high-speed charge-coupled discharge (CCD) camera is

  12. Effect of rotational speed on rapid separation of primary silicon from an Al-Si alloy by novel centrifugation

    NASA Astrophysics Data System (ADS)

    Youn, Ji Won; Jeon, Je-Beom; Hee Seo, Kum; Kim, Suk Jun; Young Kim, Ki

    2016-01-01

    The optimum rotational speed (RS) of a novel centrifugation method for obtaining high-purity Si separated from Al-Si melts was evaluated numerically and experimentally. Numerical calculations showed that the separation efficiency (Si to Al ratio in the separated solid) increases and finally reaches a plateau at a high RS. The calculated relationship between RS and the separation efficiency was consistent with experimentally measured data except for the removal of primary Si crystallites, which happened at centrifugation at 800 revolutions per minute (RPM). Based on the acquired data, it was established that 700 RPM is the optimal RS for our centrifugation apparatus (developed in a previous study) to maximize the separation efficiency.

  13. Correlation of microstructure and thermal-fatigue properties of centrifugally cast high-speed steel rolls

    NASA Astrophysics Data System (ADS)

    Kim, Chang Kyu; Park, Jong Il; Ryu, Jae Hwa; Lee, Sunghak

    2004-02-01

    This is a study of thermal-fatigue properties in centrifugally cast high-speed steel (HSS) rolls. The thermal-fatigue mechanism was investigated, with special focus on the roll microstructure and the increase in tensile stress which led the specimens to fracture when it reached the tensile strength. The thermal-fatigue test results indicated that the thermal-fatigue life decreased with increasing maximum temperature of the thermal-fatigue cycle. The results were then interpreted based on the amount of carbides and the cyclic-softening phenomenon associated with the exposed time to elevated temperatures. The coarse intercellular carbides on the specimen surface acted as fatigue-crack initiation sites as they cleaved at a low stress level to form cracks. The roll having the lowest matrix hardness and the smallest amount of intercellular carbides, thus, showed better thermal fatigue properties than the other rolls. For the improvement of the thermal-fatigue properties of the rolls, this study suggests a homogeneous distribution of carbides by reducing the carbide segregation formed along the solidification cell boundary and by optimizing the roll compositions.

  14. An Investigation of Surge in a High-Speed Centrifugal Compressor Using Digital PIV

    NASA Technical Reports Server (NTRS)

    Wernet, Mark P.; Bright, Michelle M.; Skoch, Gary J.

    2001-01-01

    Compressor stall is a catastrophic breakdown of the flow in a compressor, which con lead to a loss of engine power, large pressure transients in the inlet/nacelle, and engine flameout. The implementation of active or passive strategies for controlling rotating stall and surge can significantly extend the stable operating range of a compressor without substantially sacrificing performance. It is crucial to identify the dynamic changes occurring in the flow field prior to rotating stall and surge in order to control these events successfully. Generally, pressure transducer measurements are made to capture the transient response of a compressor prior to rotating stall. In this investigation, Digital Particle Imaging Velocimetry (DPIV) is used in conjunction with dynamic pressure transducers to capture transient velocity and pressure measurements simultaneously in the nonstationary flow field during compressor surge. DPIV is an instantaneous, planar measurement technique that is ideally suited for studying transient flow phenomena in highspeed turbomachinery and has been used previously to map the stable operating point flow field in the diffuser of a high-speed centrifugal compressor. Through the acquisition of both DPIV images and transient pressure data, the time evolution of the unsteady flow during surge is revealed.

  15. Numerical study of unsteady flows with cavitation in a high-speed micro centrifugal pump

    NASA Astrophysics Data System (ADS)

    Li, Yeqiang; Yuan, Shiwei; Lai, Huanxin

    2017-02-01

    The unsteady flows caused by the interaction between the impeller and the volute in a high-speed micro centrifugal pump are numerically studied. The internal flows of both with and without cavitations are analyzed using the CFX. The characteristics of unsteady pressure on the blade surfaces and the symmetric plane of the volute are presented and compared. The results show that the amplitudes of pressure fluctuations of critical cavitation on the blade pressure surface (PS) are bigger as compared with those at the non-cavitation condition, but on the suction surface (SS), the situation is on the contrary. When cavitation occurs, reduction of load in the impeller is a result. In the present study, such reduction of load is observed mainly on the first half of the blades. Pressure fluctuations at five monitoring points, denoted by WK1 to WK5 in the volute, are also analyzed. No matter at the critical cavitation or at the non-cavitation conditions, the monitored pressure fluctuations are at the same frequencies, which equal to the blade passing frequency (BPF) and its multiples. However, the amplitudes of the fluctuations at critical cavitation condition are considerably stronger, as compared with those for without cavitation.

  16. Development of the seeding system used for laser velocimeter surveys of the NASA Low-Speed Centrifugal Compressor flow field

    NASA Technical Reports Server (NTRS)

    Wasserbauer, Charles A.; Hathaway, Michael D.

    1993-01-01

    An atomizer-based system for distributing high-volume rates of seed material was developed to support laser velocimeter investigations of the NASA Low-Speed Centrifugal Compressor flow field. The seeding system and the major concerns that were addressed during its development are described. Of primary importance were that the seed material be dispersed as single particles and that the liquid carrier used be completely evaporated before entering the compressor.

  17. NASA low-speed centrifugal compressor for 3-D viscous code assessment and fundamental flow physics research

    NASA Technical Reports Server (NTRS)

    Hathaway, M. D.; Wood, J. R.; Wasserbauer, C. A.

    1991-01-01

    A low speed centrifugal compressor facility recently built by the NASA Lewis Research Center is described. The purpose of this facility is to obtain detailed flow field measurements for computational fluid dynamic code assessment and flow physics modeling in support of Army and NASA efforts to advance small gas turbine engine technology. The facility is heavily instrumented with pressure and temperature probes, both in the stationary and rotating frames of reference, and has provisions for flow visualization and laser velocimetry. The facility will accommodate rotational speeds to 2400 rpm and is rated at pressures to 1.25 atm. The initial compressor stage being tested is geometrically and dynamically representative of modern high-performance centrifugal compressor stages with the exception of Mach number levels. Preliminary experimental investigations of inlet and exit flow uniformly and measurement repeatability are presented. These results demonstrate the high quality of the data which may be expected from this facility. The significance of synergism between computational fluid dynamic analysis and experimentation throughout the development of the low speed centrifugal compressor facility is demonstrated.

  18. The effects of the centrifugation speed on the survival of autogenous fat grafts in a rat model.

    PubMed

    Bozkurt, Mehmet; Kapı, Emin; Şirinoğlu, Hakan; Güvercin, Emre; Filinte, Gaye Taylan; Filinte, Deniz

    2016-06-01

    Purpose The most important problem in fat transplantation is the durability, which is closely associated with the applied technique. This study includes the comparison of different centrifugation speeds on the survival of autogenous fat grafts in rats. Materials and methods Forty-nine Sprague-Dawley rats were divided into seven groups and the left inguinal fat pad was extracted and re-implanted under the scalp after performing appropriate preparation processes. In the first group the fatty tissue was re-implanted in en-bloc fashion and in the second group it was re-implanted after trimming. After trimming, centrifugation with a G-force of 111.8 (1000 rpm) was performed in the third group, 447.2 (2000 rpm) in the fourth group, 1006.2 (3000 rpm) in the fifth group, 1788.8 (4000 rpm) in the sixth group, and 2795 (5000 rpm) in the seventh group for 4 minutes. The fat grafts were taken after 3 months and histopathological and statistical evaluations were performed. Results The rate of viable fat grafts was significantly higher in the 4th and 5th groups comparing to the first three groups. Total weight and volume amounts of the 4th and 5th groups were also significantly higher comparing to the first three groups. Conclusion Maximal long-term durability and fat cell viability results were obtained in the groups with 2000 rpm or 447.2 G-force/4 minutes and 3000 rpm or 1006.2 G-force/4 minutes centrifugation speed, indicating that 4 minutes centrifugation with an average G-force of 698.75 or 2500 rpm provides the best results for the survival of autogenous fat grafts.

  19. Study of interactions between cells and microbubbles in high speed centrifugation field for biomolecule delivery.

    PubMed

    He, Chuan; Chen, Jie

    2014-01-01

    Biomolecule delivery has a very wide range of applications in biology and medicine. In this study, a microbubble based delivery method was developed. In a high centrifugation field, cells deform and collide with microbubbles to induce intracellular pathways on cell membranes. As a result, biomaterials can then easily enter cells. Experimental results show that this delivery method can achieve high delivery efficiency. Simulation results showed that cells with more deformed structure experienced higher strain on cell membranes than cells with less deformed structure. The models can help explain how centrifugation affects cell membrane permeability. By controlling cell morphology and its mechanical properties, high biomolecule delivery efficiency can be achieved.

  20. The method of the gas-dynamic centrifugal compressor stage characteristics recalculation for variable rotor rotational speeds and the rotation angle of inlet guide vanes blades if the kinematic and dynamic similitude conditions are not met

    NASA Astrophysics Data System (ADS)

    Vanyashov, A. D.; Karabanova, V. V.

    2017-08-01

    A mathematical description of the method for obtaining gas-dynamic characteristics of a centrifugal compressor stage is proposed, taking into account the control action by varying the rotor speed and the angle of rotation of the guide vanes relative to the "basic" characteristic, if the kinematic and dynamic similitude conditions are not met. The formulas of the correction terms for the non-dimensional coefficients of specific work, consumption and efficiency are obtained. A comparative analysis of the calculated gas-dynamic characteristics of a high-pressure centrifugal stage with experimental data is performed.

  1. Low speed centrifugal casting of Functionally Graded solid cast ingot by anomalous particle distribution

    NASA Astrophysics Data System (ADS)

    Mer, K. K. S.; Ray, S.

    2011-12-01

    Functionally graded cylindrical ingot of Al-Al2O3 composite synthesized by centrifugal casting shows particle distribution and hardness decreasing radially from the outer radius to inner radius. The progressive decrease in alumina content and hardness from the outer radius towards the center may be attributed to higher centrifugal force acting on relatively denser alumina particles during rotation, as compared to that acting on lighter alloy melt. It is also observed, as one moves down from the top to the bottom of cast ingot the alumina content decreases. This is surprising in view of higher density of alumina particles relative to the melt. The particle settling should have resulted at more particles towards the bottom, but distribution observed is in contradiction.

  2. Completely pulsatile high flow circulatory support with a constant-speed centrifugal blood pump: mechanisms and early clinical observations.

    PubMed

    Yamazaki, Kenji; Saito, Satoshi; Kihara, Shinichiro; Tagusari, Osamu; Kurosawa, Hiromi

    2007-04-01

    Various types of rotary blood pumps (axial flow, centrifugal) have been introduced into clinical use recently. These pumps have different pressure-flow characteristics, and some investigators have noted that a limited pump flow rate and less pulsatility are the problems with the axial flow devices. A new implantable centrifugal blood pump was developed that has an extremely flat pressure-flow curve and is able to produce a significantly high pump flow rate of 20 l/min at a low pressure of 10-30mmHg. When the pressure difference between the left ventricle and aorta decreases during systole, an instant high peak flow is achieved, which results in a higher peak pressure in the aorta (systolic pressure). During the diastolic phase, the left ventricle-aorta pressure difference increases to maximum, and the pump flow rate decreases to minimum. Thus, the pump flow rate becomes completely pulsatile, and the high peak flow provides a higher mean pump flow rate. This pump was applied to two end-stage heart failure patients (dilated cardiomyopathy, New York Heart Association (NYHA) class IV, inotrope-dependent). The pump was observed to provide completely pulsatile high flow assistance of 6-9 l/min with a constant pump speed. Both patients are currently in NYHA class I after 1 year on the device with no major adverse events. The new centrifugal blood pump provides completely pulsatile high-flow circulatory support with a constant pump speed, which solves the current clinical problems with rotary blood pumps.

  3. The Use of a "Qual" Centrifuge for Greatly Simplifying and Speeding the Study of Milk

    NASA Astrophysics Data System (ADS)

    Petersen, Quentin R.

    1996-09-01

    Laboratory study of the constituents of milk is almost always slowed by difficult separation of relatively large amounts of curd and whey by filtration. In the two-and-one-half hour experiment described, only 5 mL of skim milk is used and the curd is separated from the whey by using a simple "qual" centrifuge. Casein and serum proteins are quickly isolated as solids in essentially-quantitative yields in a procedure utilizing only two 13 x 100 mm test tubes and a 50 mL beaker along with the centrifuge and a hotplate. Protein solutions are prepared in the test tubes in which they were isolated and subjected to a variety of classical tests, the most dramatic of which is the Hopkins-Cole test which shows the presence of tryptophan in casein and its absence in serum protein. An essentially-quantitative yield of solid lactose is obtained by evaporation of the supernatant liquid obtained from the serum protein centrifugation. A lactose solution is subjected to Benedict's and Barfoed's tests, identifying it as a disaccharide. Sufficient time is available to compare the fat and enzyme contents of raw milk and skim milk.

  4. Measurement of rock-core capillary pressure curves using a single-speed centrifuge and one-dimensional magnetic-resonance imaging

    NASA Astrophysics Data System (ADS)

    Chen, Quan; Balcom, Bruce J.

    2005-06-01

    Capillary pressure curves are widely used in materials, soil, and environmental sciences, and especially in the petroleum industry. The traditional (Hassler-Brunner) interpretation of centrifugal capillary pressure data is based on several assumptions. These assumptions are known to lead to significant errors in the measurement of capillary pressure curves. In this work, we propose a new "single-shot" method to measure the capillary pressure curve of a long sedimentary rock core using a single-speed centrifuge experiment and magnetic-resonance imaging to directly determine the water saturation distribution along the length of the sample. Since only a single moderate centrifuge speed is employed, the effect of gravity can be ignored and the outlet boundary condition of the core plug was maintained. The capillary pressure curve obtained by the single-shot method is remarkably consistent with results determined with conventional mercury-intrusion methods. The proposed method is much faster and more precise than traditional centrifuge methods.

  5. Hydraulic losses in the spiral case of low specific speed pumps

    NASA Astrophysics Data System (ADS)

    Klas, Roman; Pochylý, František; Rudolf, Pavel

    2014-03-01

    This contribution is focused on analysis of pressure losses in spiral case of centrifugal pump with thick trailing edges and with recirculation channels. Recirculation channels have different geometrical configuration and influence the size of available specific energy as well as hydraulic efficiency. Subsequently, the contribution analyses the flow in spiral case itself with respect to its function and its filling with liquid. Studied phenomena affect the research of pumps with low specific speed, the stability of specific energy characteristic curves and also the configuration of recirculation channels.

  6. Determination of the specific gravity of certain helminth eggs using sucrose density gradient centrifugation.

    PubMed

    David, E D; Lindquist, W D

    1982-10-01

    The specific gravities of ten species of helminth eggs were determined using sucrose density gradient centrifugation. Fecal or egg concentrate was layered over a 3 to 54% sucrose density gradient. The gradient was then centrifuged at 800 g for 20 min, allowing 5 min for acceleration and 5 for deceleration. Bands formed were identified and measured. Refractive index was measured at the middle of narrow bands, or at the level at which the concentration of eggs was highest, in the case of wide bands or when no band was formed. The specific gravity corresponding to this refractive index was taken as the specific gravity of the eggs. The ten species of helminth eggs studied and specific gravities measured on three or four gradients were: Toxascaris leonina, 1.0559; Ancylostoma caninum, 1.0559; Toxocara canis, 1.0900; Parascaris equorum, 1.0969; Toxocara cati (embryonated), 1.1005; Ascaris suum, 1.1299; Trichuris suis, 1.1299; Trichuris vulpis, 1.1453; Taenia sp., 1.2251; and Physaloptera sp., 1.2376. These determinations agree with or approximate those of previous workers. The specific gravities of P. equorum, T. suis, Taenia sp., and Physaloptera sp., are reported for the first time.

  7. The Effects of Austenitizing Conditions on the Microstructure and Wear Resistance of a Centrifugally Cast High-Speed Steel Roll

    NASA Astrophysics Data System (ADS)

    Kang, Minwoo; Lee, Young-Kook

    2016-07-01

    The influences of austenitizing conditions on the microstructure and wear resistance of a centrifugally cast high-speed steel roll were investigated through thermodynamic calculation, microstructural analysis, and high-temperature wear tests. When the austenitizing temperature was between 1323 K and 1423 K (1050 °C and 1150 °C), coarse eutectic M2C plates were decomposed into a mixture of MC and M6C particles. However, at 1473 K (1200 °C), the M2C plates were first replaced by both new austenite grains and MC particles without M6C particles, and then remaining M2C particles were dissolved during the growth of MC particles. The wear resistance of the HSS roll was improved with increasing austenitizing temperature up to 1473 K (1200 °C) because the coarse eutectic M2C plates, which are vulnerable to crack propagation, changed to disconnected hard M6C and MC particles.

  8. Laser Anemometer Measurements of the Three-Dimensional Rotor Flow Field in the NASA Low-Speed Centrifugal Compressor

    NASA Technical Reports Server (NTRS)

    Hathaway, Michael D.; Chriss, Randall M.; Strazisar, Anthony J.; Wood, Jerry R.

    1995-01-01

    A laser anemometer system was used to provide detailed surveys of the three-dimensional velocity field within the NASA low-speed centrifugal impeller operating with a vaneless diffuser. Both laser anemometer and aerodynamic performance data were acquired at the design flow rate and at a lower flow rate. Floor path coordinates, detailed blade geometry, and pneumatic probe survey results are presented in tabular form. The laser anemometer data are presented in the form of pitchwise distributions of axial, radial, and relative tangential velocity on blade-to-blade stream surfaces at 5-percent-of-span increments, starting at 95-percent-of-span from the hub. The laser anemometer data are also presented as contour and wire-frame plots of throughflow velocity and vector plots of secondary velocities at all measurement stations through the impeller.

  9. Influence of rotational speed of centrifugal casting process on appearance, microstructure, and sliding wear behaviour of Al-2Si cast alloy

    NASA Astrophysics Data System (ADS)

    Mukunda, P. G.; Shailesh, Rao A.; Rao, Shrikantha S.

    2010-02-01

    Although the manner in which the molten metal flows plays a major role in the formation of the uniform cylinder in centrifugal casting, not much information is available on this topic. The flow in the molten metal differs at various rotational speeds, which in turn affects the final casting. In this paper, the influence of the flow of molten metal of hyper eutectic Al-2Si alloys at various rotational speeds is discussed. At an optimum speed of 800 rpm, a uniform cylinder was formed. For the rotational speeds below and above these speeds, an irregular shaped casting was formed, which is mainly due to the influence of melt. Primary á-Al particles were formed in the tube periphery at low rotational speed, and their sizes and shapes were altered with changes in rotational speeds. The wear test for the inner surface of the casting showed better wear properties for the casting prepared at the optimum speed of rotation.

  10. Purification of Proteins From Cell-Culture Medium or Cell-Lysate by High-Speed Counter-Current Chromatography Using Cross-Axis Coil Planet Centrifuge

    PubMed Central

    Shibusawa, Yoichi; Ito, Yoichiro

    2014-01-01

    This review describes protein purifications from cell culture medium or cell-lysate by high speed counter-current chromatography using the cross-axis coil planet centrifuge. Purifications were performed using aqueous two phase systems composed of polyethylene glycols and dextrans. PMID:25360182

  11. Feedforward compensation control of rotor imbalance for high-speed magnetically suspended centrifugal compressors using a novel adaptive notch filter

    NASA Astrophysics Data System (ADS)

    Zheng, Shiqiang; Feng, Rui

    2016-03-01

    This paper introduces a feedforward control strategy combined with a novel adaptive notch filter to solve the problem of rotor imbalance in high-speed Magnetically Suspended Centrifugal Compressors (MSCCs). Unbalance vibration force of rotor in MSCC is mainly composed of current stiffness force and displacement stiffness force. In this paper, the mathematical model of the unbalance vibration with the proportional-integral-derivative (PID) control laws is presented. In order to reduce the unbalance vibration, a novel adaptive notch filter is proposed to identify the synchronous frequency displacement of the rotor as a compensation signal to eliminate the current stiffness force. In addition, a feedforward channel from position component to control output is introduced to compensate displacement stiffness force to achieve a better performance. A simplified inverse model of power amplifier is included in the feedforward channel to reject the degrade performance caused by its low-pass characteristic. Simulation and experimental results on a MSCC demonstrate a significant effect on the synchronous vibration suppression of the magnetically suspended rotor at a high speed.

  12. Effects of Alloying Elements on Microstructure, Hardness, Wear Resistance, and Surface Roughness of Centrifugally Cast High-Speed Steel Rolls

    NASA Astrophysics Data System (ADS)

    Ha, Dae Jin; Sung, Hyo Kyung; Park, Joon Wook; Lee, Sunghak

    2009-11-01

    A study was made of the effects of carbon, tungsten, molybdenum, and vanadium on the wear resistance and surface roughness of five high-speed steel (HSS) rolls manufactured by the centrifugal casting method. High-temperature wear tests were conducted on these rolls to experimentally simulate the wear process during hot rolling. The HSS rolls contained a large amount (up to 25 vol pct) of carbides, such as MC, M2C, and M7C3 carbides formed in the tempered martensite matrix. The matrix consisted mainly of tempered lath martensite when the carbon content in the matrix was small, and contained a considerable amount of tempered plate martensite when the carbon content increased. The high-temperature wear test results indicated that the wear resistance and surface roughness of the rolls were enhanced when the amount of hard MC carbides formed inside solidification cells increased and their distribution was homogeneous. The best wear resistance and surface roughness were obtained from a roll in which a large amount of MC carbides were homogeneously distributed in the tempered lath martensite matrix. The appropriate contents of the carbon equivalent, tungsten equivalent, and vanadium were 2.0 to 2.3, 9 to 10, and 5 to 6 pct, respectively.

  13. An investigational study of minimum rotational pump speed to avoid retrograde flow in three centrifugal blood pumps in a pediatric extracorporeal life support model.

    PubMed

    Clark, Joseph B; Guan, Yulong; McCoach, Robert; Kunselman, Allen R; Myers, John L; Undar, Akif

    2011-05-01

    During extracorporeal life support with centrifugal blood pumps, retrograde pump flow may occur when the pump revolutions decrease below a critical value determined by the circuit resistance and the characteristics of the pump. We created a laboratory model to evaluate the occurrence of retrograde flow in each of three centrifugal blood pumps: the Rotaflow, the CentriMag, and the Bio-Medicus BP-50. At simulated patient pressures of 60, 80, and 100 mmHg, each pump was evaluated at speeds from 1000 to 2200 rpm and flow rates were measured. Retrograde flow occurred at low revolution speeds in all three centrifugal pumps. The Bio-Medicus pump was the least likely to demonstrate retrograde flow at low speeds, followed by the Rotaflow pump. The CentriMag pump showed the earliest transition to retrograde flow, as well as the highest degree of retrograde flow. At every pump speed evaluated, the Bio-Medicus pump delivered the highest antegrade flow and the CentriMag pump delivered the least.

  14. 40 CFR Table 1 to Subpart Wwww of... - Equations To Calculate Organic HAP Emissions Factors for Specific Open Molding and Centrifugal...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 12 2011-07-01 2009-07-01 true Equations To Calculate Organic HAP Emissions Factors for Specific Open Molding and Centrifugal Casting Process Streams 1 Table 1 to Subpart... Specific Open Molding and Centrifugal Casting Process Streams ER25AU05.020 ER25AU05.021...

  15. 40 CFR Table 1 to Subpart Wwww of... - Equations To Calculate Organic HAP Emissions Factors for Specific Open Molding and Centrifugal...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 13 2013-07-01 2012-07-01 true Equations To Calculate Organic HAP Emissions Factors for Specific Open Molding and Centrifugal Casting Process Streams 1 Table 1 to Subpart... Factors for Specific Open Molding and Centrifugal Casting Process Streams ER25AU05.020 ER25AU05.021...

  16. 40 CFR Table 1 to Subpart Wwww of... - Equations To Calculate Organic HAP Emissions Factors for Specific Open Molding and Centrifugal...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 13 2014-07-01 2014-07-01 false Equations To Calculate Organic HAP Emissions Factors for Specific Open Molding and Centrifugal Casting Process Streams 1 Table 1 to Subpart... Factors for Specific Open Molding and Centrifugal Casting Process Streams ER25AU05.020 ER25AU05.021...

  17. 40 CFR Table 1 to Subpart Wwww of... - Equations To Calculate Organic HAP Emissions Factors for Specific Open Molding and Centrifugal...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 13 2012-07-01 2012-07-01 false Equations To Calculate Organic HAP Emissions Factors for Specific Open Molding and Centrifugal Casting Process Streams 1 Table 1 to Subpart... Factors for Specific Open Molding and Centrifugal Casting Process Streams ER25AU05.020 ER25AU05.021...

  18. 40 CFR Table 1 to Subpart Wwww of... - Equations To Calculate Organic HAP Emissions Factors for Specific Open Molding and Centrifugal...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Emissions Factors for Specific Open Molding and Centrifugal Casting Process Streams 1 Table 1 to Subpart... (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES National Emissions... Specific Open Molding and Centrifugal Casting Process Streams ER25AU05.020 ER25AU05.021 ...

  19. Reduction of relative centrifugation force within injectable platelet-rich-fibrin (PRF) concentrates advances patients' own inflammatory cells, platelets and growth factors: the first introduction to the low speed centrifugation concept.

    PubMed

    Choukroun, J; Ghanaati, S

    2017-03-10

    The aim of this study was to analyze systematically the influence of the relative centrifugation force (RCF) on leukocytes, platelets and growth factor release within fluid platelet-rich fibrin matrices (PRF). Systematically using peripheral blood from six healthy volunteers, the RCF was reduced four times for each of the three experimental protocols (I-III) within the spectrum (710-44 g), while maintaining a constant centrifugation time. Flow cytometry was applied to determine the platelets and leukocyte number. The growth factor concentration was quantified 1 and 24 h after clotting using ELISA. Reducing RCF in accordance with protocol-II (177 g) led to a significantly higher platelets and leukocytes numbers compared to protocol-I (710 g). Protocol-III (44 g) showed a highly significant increase of leukocytes and platelets number in comparison to -I and -II. The growth factors' concentration of VEGF and TGF-β1 was significantly higher in protocol-II compared to -I, whereas protocol-III exhibited significantly higher growth factor concentration compared to protocols-I and -II. These findings were observed among 1 and 24 h after clotting, as well as the accumulated growth factor concentration over 24 h. Based on the results, it has been demonstrated that it is possible to enrich PRF-based fluid matrices with leukocytes, platelets and growth factors by means of a single alteration of the centrifugation settings within the clinical routine. We postulate that the so-called low speed centrifugation concept (LSCC) selectively enriches leukocytes, platelets and growth factors within fluid PRF-based matrices. Further studies are needed to evaluate the effect of cell and growth factor enrichment on wound healing and tissue regeneration while comparing blood concentrates gained by high and low RCF.

  20. Reduction of relative centrifugal forces increases growth factor release within solid platelet-rich-fibrin (PRF)-based matrices: a proof of concept of LSCC (low speed centrifugation concept).

    PubMed

    El Bagdadi, K; Kubesch, A; Yu, X; Al-Maawi, S; Orlowska, A; Dias, A; Booms, P; Dohle, E; Sader, R; Kirkpatrick, C J; Choukroun, J; Ghanaati, S

    2017-03-21

    Purpose The present study evaluated the platelet distribution pattern and growth factor release (VEGF, TGF-β1 and EGF) within three PRF (platelet-rich-fibrin) matrices (PRF, A-PRF and A-PRF+) that were prepared using different relative centrifugation forces (RCF) and centrifugation times. Materials and methods immunohistochemistry was conducted to assess the platelet distribution pattern within three PRF matrices. The growth factor release was measured over 10 days using ELISA. Results The VEGF protein content showed the highest release on day 7; A-PRF+ showed a significantly higher rate than A-PRF and PRF. The accumulated release on day 10 was significantly higher in A-PRF+ compared with A-PRF and PRF. TGF-β1 release in A-PRF and A-PRF+ showed significantly higher values on days 7 and 10 compared with PRF. EGF release revealed a maximum at 24 h in all groups. Toward the end of the study, A-PRF+ demonstrated significantly higher EGF release than PRF. The accumulated growth factor releases of TGF-β1 and EGF on day 10 were significantly higher in A-PRF+ and A-PRF than in PRF. Moreover, platelets were located homogenously throughout the matrix in the A-PRF and A-PRF+ groups, whereas platelets in PRF were primarily observed within the lower portion. ​Discussion the present results show an increase growthfactor release by decreased RCF. However, further studies must be conducted to examine the extent to which enhancing the amount and the rate of released growth factors influence wound healing and biomaterial-based tissue regeneration. ​Conclusion These outcomes accentuate the fact that with a reduction of RCF according to the previously LSCC (described low speed centrifugation concept), growth factor release can be increased in leukocytes and platelets within the solid PRF matrices.

  1. General and specific perceptual learning in radial speed discrimination.

    PubMed

    Huang, Xuan; Lu, Hongjing; Zhou, Yifeng; Liu, Zili

    2011-04-14

    The specificity of learning in speed discrimination was examined in three psychophysical experiments. In Experiment 1, half of the observers trained with inward motion direction on a speed discrimination task, whereas the other half trained on the same task but with outward motion direction. The results indicated that significant training-based improvement transferred from a trained radial direction to an untrained radial direction. Experiment 2 confirmed this transfer by showing that complete transfer was obtained even when stimuli moving in an untrained radial direction were used in the transfer task. In Experiment 3, observers were trained at a viewing distance of 114 cm. The results showed that learning transferred partly to the viewing distances of 57 cm and 228 cm. In summary, the present transfer results indicate that reliable generalizations can be obtained in perceptual learning of radial speed discrimination.

  2. Variations in battery life of a heart-lung machine using different pump speeds, pressure loads, boot material, centrifugal pump head, multiple pump usage, and battery age.

    PubMed

    Marshall, Cornelius; Hargrove, Martin; O'Donnell, Aonghus; Aherne, Thomas

    2005-09-01

    Electrical failure during cardiopulmonary bypass (CPB) has previously been reported to occur in 1 of every 1500 cases. Most heart-lung machine pump consoles are equipped with built-in battery back-up units. Battery run times of these devices are variable and have not been reported. Different conditions of use can extend battery life in the event of electrical failure. This study was designed to examine the run time of a fully charged battery under various conditions of pump speed, pressure loads, pump boot material, multiple pump usage, and battery life. Battery life using a centrifugal pump also was examined. The results of this study show that battery life is affected by pump speed, circuit pressure, boot stiffness, and the number of pumps in service. Centrifugal pumps also show a reduced drain on battery when compared with roller pumps. These elements affect the longevity and performance of the battery. This information could be of value to the individual during power failure as these are variables that can affect the battery life during such a challenging scenario.

  3. Variations in Battery Life of a Heart—Lung Machine Using Different Pump Speeds, Pressure Loads, Boot Material, Centrifugal Pump Head, Multiple Pump Usage, and Battery Age

    PubMed Central

    Marshall, Cornelius; Hargrove, Martin; O’Donnell, Aonghus; Aherne, Thomas

    2005-01-01

    Abstract: Electrical failure during cardiopulmonary bypass (CPB) has previously been reported to occur in 1 of every 1500 cases. Most heart—lung machine pump consoles are equipped with built-in battery back-up units. Battery run times of these devices are variable and have not been reported. Different conditions of use can extend battery life in the event of electrical failure. This study was designed to examine the run time of a fully charged battery under various conditions of pump speed, pressure loads, pump boot material, multiple pump usage, and battery life. Battery life using a centrifugal pump also was examined. The results of this study show that battery life is affected by pump speed, circuit pressure, boot stiffness, and the number of pumps in service. Centrifugal pumps also show a reduced drain on battery when compared with roller pumps. These elements affect the longevity and performance of the battery. This information could be of value to the individual during power failure as these are variables that can affect the battery life during such a challenging scenario. PMID:16350380

  4. Fluid forces on rotating centrifugal impeller with whirling motion

    NASA Technical Reports Server (NTRS)

    Shoji, H.; Ohashi, H.

    1980-01-01

    Fluid forces on a centrifugal impeller, whose rotating axis whirls with a constant speed, were calculated by using unsteady potential theory. Calculations were performed for various values of whirl speed, number of impeller blades and angle of blades. Specific examples as well as significant results are given.

  5. Centrifugal compressor design for electrically assisted boost

    NASA Astrophysics Data System (ADS)

    Y Yang, M.; Martinez-Botas, R. F.; Zhuge, W. L.; Qureshi, U.; Richards, B.

    2013-12-01

    Electrically assisted boost is a prominent method to solve the issues of transient lag in turbocharger and remains an optimized operation condition for a compressor due to decoupling from turbine. Usually a centrifugal compressor for gasoline engine boosting is operated at high rotational speed which is beyond the ability of an electric motor in market. In this paper a centrifugal compressor with rotational speed as 120k RPM and pressure ratio as 2.0 is specially developed for electrically assisted boost. A centrifugal compressor including the impeller, vaneless diffuser and the volute is designed by meanline method followed by 3D detailed design. Then CFD method is employed to predict as well as analyse the performance of the design compressor. The results show that the pressure ratio and efficiency at design point is 2.07 and 78% specifically.

  6. The optimization of a low specific speed pipeline pump

    NASA Astrophysics Data System (ADS)

    Zhao, A.; Wu, P.; Wu, D. Z.; Wang, L. Q.

    2013-12-01

    A low specific speed pipeline pump is researched to improve work performance through several certain modifications. The target is to raise the pump's head up to 80m and increase its total efficiency to 26.5% when the volume flow rate is 6.3m3/h with a rotatory speed of 2960rpm. CFD Numerical simulation is employed to predict the hydraulic performance of the pump. The volute is redesigned and splitters are imported to change the structure of the impeller. A lot of factors are taken into account, for instance number of vanes, forms of vanes, width of the volute, shape of volute's cross section, etc. These transformations ameliorate the distribution of pressure and velocity in the impeller and volute that finally increase the pump's hydraulic efficiency. The impeller trim has also been made according to the affinity law to fatherly decrease the disc friction which causes pump's mechanical loss and then achieves the optimization goal finally. It is a practical case in low specific speed pump's optimization and conclusions given at the end may be experience in the design of this sort of device.

  7. Action-specific perception of speed is independent of attention.

    PubMed

    Witt, Jessica K; Sugovic, Mila; Dodd, Michael D

    2016-04-01

    According to the action-specific account of perception, a perceiver's ability to act influences how the environment is perceived. For example, in a computer-based task, participants perceive fish as moving faster when they use a smaller net, and are thus less effective at catching the fish (Witt & Sugovic, 2013a). Here, we examined the degree to which attention may influence perceptual judgments by requiring participants to engage in a secondary task that directed their attention either toward (Exp. 1) or away from (Exp. 2) the to-be-caught fish. Though perceived fish speed was influenced by participants' catching performance-replicating previous results-attentional allocation did not impact this relationship between catching performance and perceived fish speed. The present results suggest that action directly influences spatial perception, rather than exerting indirect effects via attentional processes.

  8. Experimental study of operation performance for hydrocarbon fuel pump with low specific speed

    NASA Astrophysics Data System (ADS)

    Wu, Xianyu; Yang, Jun; Jin, Xuan

    2017-10-01

    In this paper, a small flow rate hydrocarbon turbine pump was used to pressurize the fuel supply system of scramjet engine. Some experiments were carried out to investigate the characteristics of turbine pump driven by nitrogen or combustion gas under different operating conditions. A experimental database with regard to the curves of the rotational speed, mass flow rate and net head with regard to centrifugal pump were plotted. These curves were represented as functions of the pressure and temperature at turbine inlet/outlet and the throttle diameter at downstream of centrifugal pump. A sensitivity study has been carried out based on design of experiments. The experimental was employed to analyze net head of centrifugal and throttle characteristics. The research results can accumulate foundations for the close loop control system of turbine pump.

  9. The impact of homogeniser speed, dispersing aggregate size and centrifugation on particle size analyses of pork as a measure of myofibrillar fragmentation.

    PubMed

    Ngapo, T M; Vachon, L

    2017-11-01

    Particle size analysis has been proposed as a measure of myofibrillar fragmentation resulting from post-mortem proteolysis in meat. The aim of this study was to examine the effect of homogenisation speed, dispersing aggregate size and centrifugation on particle size characteristics of pork loin. Particle size characteristics were significantly (P≤0.023) greater for samples aged 2 than 8d for all but the 80 and 90% quantiles. Differentiation with ageing was only achieved when homogenised at 11,000rpm using the smaller dispersing aggregate (9 vs 13mm rotor diameters). Centrifugation had no effect on particle size characteristics. Significant correlations with MFI (r=-0.40 to -0.81, P<0.001) and shear force in meat aged at 3.7°C (r=0.36-0.47; P<0.001) were observed. Weak or inconsistent correlations with shear force suggest adoption of particle size analyses as a method of tenderness classification unlikely. Rather, value lies in the detailed profiles of particle size distributions with meat ageing. Copyright © 2017. Published by Elsevier Ltd.

  10. Novel speed test for evaluation of badminton-specific movements.

    PubMed

    Madsen, Christian M; Karlsen, Anders; Nybo, Lars

    2015-05-01

    In this study, we developed a novel badminton-specific speed test (BST). The test was designed to mimic match play. The test starts in the center of the court and consists of 5 maximal actions to sensors located in each of the 4 corners of the court. The 20 actions are performed in randomized order as dictated by computer screen shots displayed 1 second after completion of the previous action. We assessed day-to-day variation in elite players, and specificity of the test was evaluated by comparing 30-m sprint performance and time to complete the BST in 20 elite players, 21 skilled players, and 20 age-matched physical active subjects (non-badminton players). Sprint performance was similar across groups, whereas the elite players were significantly (p ≤ 0.05) faster in the BST (total test time: 32.3 ± 1.1 seconds; average: 1.6 seconds per action) than the skilled (34.1 ± 2.0 seconds) and non-badminton players (35.7 ± 1.7 seconds). Day-to-day coefficient of variation (CV) of the BST was 0.7% for the elite players, whereas CV for repeated tests on the same day was 1.7% for elite, 2.6% for skilled, and 2.5% for non-badminton players. On this basis, we suggest that the BST may be valuable for evaluation of short-term maximal movement speed in badminton players. Thus, the BST seems to be sport specific, as it may discriminate between groups (elite, less trained players, and non-badminton players) with similar sprinting performance, and the low test-retest variation may allow for using the BST to evaluate longitudinal changes, for example, training effects or seasonal variations.

  11. Correlations between adolescent processing speed and specific spindle frequencies

    PubMed Central

    Nader, Rebecca S.; Smith, Carlyle T.

    2015-01-01

    Sleep spindles are waxing and waning thalamocortical oscillations with accepted frequencies of between 11 and 16 Hz and a minimum duration of 0.5 s. Our research has suggested that there is spindle activity in all of the sleep stages, and thus for the present analysis we examined the link between spindle activity (Stage 2, rapid eye movement (REM) and slow wave sleep (SWS)) and waking cognitive abilities in 32 healthy adolescents. After software was used to filter frequencies outside the desired range, slow spindles (11.00–13.50 Hz), fast spindles (13.51–16.00 Hz) and spindle-like activity (16.01–18.50 Hz) were observed in Stage 2, SWS and REM sleep. Our analysis suggests that these specific EEG frequencies were significantly related to processing speed, which is one of the subscales of the intelligence score, in adolescents. The relationship was prominent in SWS and REM sleep. Further, the spindle-like activity (16.01–18.50 Hz) that occurred during SWS was strongly related to processing speed. Results suggest that the ability of adolescents to respond to tasks in an accurate, efficient and timely manner is related to their sleep quality. These findings support earlier research reporting relationships between learning, learning potential and sleep spindle activity in adults and adolescents. PMID:25709575

  12. Design optimization of a high specific speed Francis turbine runner

    NASA Astrophysics Data System (ADS)

    Enomoto, Y.; Kurosawa, S.; Kawajiri, H.

    2012-11-01

    Francis turbine is used in many hydroelectric power stations. This paper presents the development of hydraulic performance in a high specific speed Francis turbine runner. In order to achieve the improvements of turbine efficiency throughout a wide operating range, a new runner design method which combines the latest Computational Fluid Dynamics (CFD) and a multi objective optimization method with an existing design system was applied in this study. The validity of the new design system was evaluated by model performance tests. As the results, it was confirmed that the optimized runner presented higher efficiency compared with an originally designed runner. Besides optimization of runner, instability vibration which occurred at high part load operating condition was investigated by model test and gas-liquid two-phase flow analysis. As the results, it was confirmed that the instability vibration was caused by oval cross section whirl which was caused by recirculation flow near runner cone wall.

  13. Development and numerical analysis of low specific speed mixed-flow pump

    NASA Astrophysics Data System (ADS)

    Li, H. F.; Huo, Y. W.; Pan, Z. B.; Zhou, W. C.; He, M. H.

    2012-11-01

    With the development of the city, the market of the mixed flow pump with large flux and high head is prospect. The KSB Shanghai Pump Co., LTD decided to develop low speed specific speed mixed flow pump to meet the market requirements. Based on the centrifugal pump and axial flow pump model, aiming at the characteristics of large flux and high head, a new type of guide vane mixed flow pump was designed. The computational fluid dynamics method was adopted to analyze the internal flow of the new type model and predict its performances. The time-averaged Navier-Stokes equations were closed by SST k-ω turbulent model to adapt internal flow of guide vane with larger curvatures. The multi-reference frame(MRF) method was used to deal with the coupling of rotating impeller and static guide vane, and the SIMPLEC method was adopted to achieve the coupling solution of velocity and pressure. The computational results shows that there is great flow impact on the head of vanes at different working conditions, and there is great flow separation at the tailing of the guide vanes at different working conditions, and all will affect the performance of pump. Based on the computational results, optimizations were carried out to decrease the impact on the head of vanes and flow separation at the tailing of the guide vanes. The optimized model was simulated and its performance was predicted. The computational results show that the impact on the head of vanes and the separation at the tailing of the guide vanes disappeared. The high efficiency of the optimized pump is wide, and it fit the original design destination. The newly designed mixed flow pump is now in modeling and its experimental performance will be getting soon.

  14. CENTRIFUGAL SEPARATORS

    DOEpatents

    Skarstrom, C.

    1959-03-10

    A centrifugal separator is described for separating gaseous mixtures where the temperature gradients both longitudinally and radially of the centrifuge may be controlled effectively to produce a maximum separation of the process gases flowing through. Tbe invention provides for the balancing of increases and decreases in temperature in various zones of the centrifuge chamber as the result of compression and expansions respectively, of process gases and may be employed effectively both to neutralize harmful temperature gradients and to utilize beneficial temperaturc gradients within the centrifuge.

  15. Development of the Seeding System Used for Laser Velocimeter Surveys of the NASA Low-Speed Centrifugal Compressor Flow Field

    NASA Technical Reports Server (NTRS)

    Wasserbauer, C. A.; Hathaway, M. D.

    1994-01-01

    Consideration is given to an atomizer-based system for distributing high-volume rates of polystyrene latex (PSL) seed material developed to support laser velocimeter investigations of the NASA Low-Speed Compressor flow field. Complete evaporation of the liquid carrier before the flow entering the compressor was of primary concern for the seeder system design. It is argued that the seed nozzle should incorporate a needle valve that can mechanically dislodge accumulated PSL seed material when the nozzle is turned off. Water is less expensive as the liquid carrier and should be used whenever adequate residence times are available to ensure complete evaporation. PSL agglomerates over time and needs to be mixed or blended before use. Arrangement of the spray nozzles needs to be adjustable to provide maximum seeding at the laser probe volume.

  16. Development of the Seeding System Used for Laser Velocimeter Surveys of the NASA Low-Speed Centrifugal Compressor Flow Field

    NASA Technical Reports Server (NTRS)

    Wasserbauer, C. A.; Hathaway, M. D.

    1994-01-01

    Consideration is given to an atomizer-based system for distributing high-volume rates of polystyrene latex (PSL) seed material developed to support laser velocimeter investigations of the NASA Low-Speed Compressor flow field. Complete evaporation of the liquid carrier before the flow entering the compressor was of primary concern for the seeder system design. It is argued that the seed nozzle should incorporate a needle valve that can mechanically dislodge accumulated PSL seed material when the nozzle is turned off. Water is less expensive as the liquid carrier and should be used whenever adequate residence times are available to ensure complete evaporation. PSL agglomerates over time and needs to be mixed or blended before use. Arrangement of the spray nozzles needs to be adjustable to provide maximum seeding at the laser probe volume.

  17. Centrifugally decoupling touchdown bearings

    DOEpatents

    Post, Richard F

    2014-06-24

    Centrifugally decoupling mechanical bearing systems provide thin tensioned metallic ribbons contained in a support structure. This assembly rotates around a stationary shaft being centered at low speeds by the action of the metal ribbons. Tension springs are connected on one end to the ribbons and on the other end to the support structure. The ribbons pass through slots in the inner ring of the support structure. The spring preloading thus insures contact (or near-contact) between the ribbons and the shaft at rotation speeds below the transition speed. Above this speed, however, the centrifugal force on the ribbons produces a tensile force on them that exceeds the spring tensile force so that the ribbons curve outward, effectively decoupling them from mechanical contact with the shaft. They still remain, however, in position to act as a touchdown bearing in case of abnormally high transverse accelerations.

  18. Specification and analysis of a high speed transport protocol

    NASA Astrophysics Data System (ADS)

    Tipici, Huseyin A.

    1993-06-01

    While networks have been getting faster, perceived throughput at the application has not always increased accordingly and the bottleneck has moved to the communications processing part of the system. The issues that cause the performance bottlenecks in the current transport protocols are discussed in this thesis, and a further study on a high speed transport protocol which tries to overcome these difficulties with some unique features is presented. By using the Systems of Communicating Machines (SCM) model as a framework, a refined and improved version of the formal protocol specification is built over the previous work, and it is analyzed to verify that the protocol is free from logical errors such as deadlock, unspecified reception, unexecuted transitions and blocking loops. The analysis is conducted in two phases which consists of the application of the associated system state analysis and the simulation of the protocol using the programming language ADA. The thesis also presents the difficulties encountered during the course of the analysis, and suggests possible solutions to some of the problems.

  19. Numerical Investigations of Slip Phenomena in Centrifugal Compressor Impellers

    NASA Astrophysics Data System (ADS)

    Huang, Jeng-Min; Luo, Kai-Wei; Chen, Ching-Fu; Chiang, Chung-Ping; Wu, Teng-Yuan; Chen, Chun-Han

    2013-03-01

    This study systematically investigates the slip phenomena in the centrifugal air compressor impellers by CFD. Eight impeller blades for different specific speeds, wrap angles and exit blade angles are designed by compressor design software to analyze their flow fields. Except for the above three variables, flow rate and number of blades are the other two. Results show that the deviation angle decreases as the flow rate increases. The specific speed is not an important parameter regarding deviation angle or slip factor for general centrifugal compressor impellers. The slip onset position is closely related to the position of the peak value in the blade loading factor distribution. When no recirculation flow is present at the shroud, the variations of slip factor under various flow rates are mainly determined by difference between maximum blade angle and exit blade angle, Δβmax-2. The solidity should be of little importance to slip factor correlations in centrifugal compressor impellers.

  20. Attack on centrifugal costs

    SciTech Connect

    Murray, P.F.

    1986-03-01

    The Monsanto Chocolate Bayou plant has had an aggressive and successful energy conservation program. The combined efforts have resulted in a 80% reduction in unit energy consumption compared to 1972. The approach of using system audits to optimize fluid systems was developed. Since most of the fluid movers are centrifugal, the name Centrifugal Savings Task Force was adopted. There are three tools that are particularly valuable in optimizing fluid systems. First, a working level understanding of the Affinity Laws seems a must. In addition, the performance curves for the fluid movers is needed. The last need is accurate system field data. Systems effectively managed at the Chocolate Bayou plant were process air improvement, feed-water pressure reduction, combustion air blower turbine speed control, and cooling tower pressure reduction. Optimization of centrifugal systems is an often-overlooked opportunity for energy savings. The basic guidelines are to move only the fluid needed, and move it at as low a pressure as possible.

  1. Centrifuge apparatus

    DOEpatents

    Sartory, Walter K.; Eveleigh, John W.

    1976-01-01

    A method and apparatus for operating a continuous flow blood separation centrifuge are provided. The hematocrit of the entrant whole blood is continuously maintained at an optimum constant value by the addition of plasma to the entrant blood. The hematocrit of the separated red cells is monitored to indicate the degree of separation taking place, thereby providing a basis for regulating the flow through the centrifuge.

  2. Specificity of acceleration, maximum speed, and agility in professional soccer players.

    PubMed

    Little, Thomas; Williams, Alun G

    2005-02-01

    High-speed actions are known to impact soccer performance and can be categorized into actions requiring maximal speed, acceleration, or agility. Contradictory findings have been reported as to the extent of the relationship between the different speed components. This study comprised 106 professional soccer players who were assessed for 10-m sprint (acceleration), flying 20-m sprint (maximum speed), and zigzag agility performance. Although performances in the three tests were all significantly correlated (p < 0.0005), coefficients of determination (r(2)) between the tests were just 39, 12, and 21% for acceleration and maximum speed, acceleration and agility, and maximum speed and agility, respectively. Based on the low coefficients of determination, it was concluded that acceleration, maximum speed, and agility are specific qualities and relatively unrelated to one another. The findings suggest that specific testing and training procedures for each speed component should be utilized when working with elite players.

  3. Application of centrifugal precipitation chromatography and high-speed counter-current chromatography equipped with a spiral tubing support rotor for the isolation and partial characterization of carotenoid cleavage-like enzymes in Enteromorpha compressa (L.) Nees.

    PubMed

    Baldermann, Susanne; Mulyadi, Andriati N; Yang, Ziyin; Murata, Ariaka; Fleischmann, Peter; Winterhalter, Peter; Knight, Martha; Finn, Thomas M; Watanabe, Naoharu

    2011-10-01

    Centrifugal precipitation chromatography and a high-speed counter-current chromatography system equipped with a spiral tubing support rotor (spHSCCC) were successfully applied for the identification and isolation of carotenoid cleavage-like enzymes from Enteromorpha compressa (L.) Nees. This is the first study separating active enzymes from a complex natural matrix by spHSCCC. The target enzymes were identified after fractionation of the proteins in an acetone Tris-buffer gradient by centrifugal precipitation chromatography. Also, an aqueous two-phase solvent system consisting of PEG 1000 and mono- and dibasic potassium phosphate was used for the isolation of the enzymes by spHSCCC. The purified fractions contained two proteins of 65 and 72 kDa, respectively. The enzymes could cleave β-carotene and β-apo-8'-carotenal to produce β-ionone.

  4. National geotechnical centrifuge

    NASA Technical Reports Server (NTRS)

    Hallam, J. A.; Kunz, N.; Vallotton, W. C.

    1982-01-01

    A high G-ton centrifuge, able to take a 2700 kg (6000 lb) payload up to 300 G, is described. The stability of dams and embankments, the bearing capacity of soil foundations, and the dynamic behavior of foundations due to vibration of machinery are examples of applications. A power rating of 6,000 kW (9,000 hp) was established for the motor. An acceptable maximum speed of 70 rpm was determined. A speed increase with a ratio of 1:3 is discussed. The isolated tension straps, the anti-spreader bar and the flexwall bucket, and safety precautions are also discussed.

  5. National geotechnical centrifuge

    NASA Astrophysics Data System (ADS)

    Hallam, J. A.; Kunz, N.; Vallotton, W. C.

    1982-05-01

    A high G-ton centrifuge, able to take a 2700 kg (6000 lb) payload up to 300 G, is described. The stability of dams and embankments, the bearing capacity of soil foundations, and the dynamic behavior of foundations due to vibration of machinery are examples of applications. A power rating of 6,000 kW (9,000 hp) was established for the motor. An acceptable maximum speed of 70 rpm was determined. A speed increase with a ratio of 1:3 is discussed. The isolated tension straps, the anti-spreader bar and the flexwall bucket, and safety precautions are also discussed.

  6. A step in embryonic axis specification in Xenopus laevis is simulated by cytoplasmic displacements elicited by gravity and centrifugal force

    NASA Astrophysics Data System (ADS)

    Black, Steven D.

    Determination of the body pattern in Xenopus embryos is known to involve at least six steps. One of these steps can be experimentally simulated by inclining the fertilized egg with respect to gravity or centrifugal force (10-30 g × 4 min, directed 90° to the animal-vegetal axis). In these eggs, the dorsal structures of the body axis form from the side of the egg that was uppermost in the gravitational or centrifugal field. This topography is seen even if the sperm entry point side (the prospective ventral side in control eggs) was uppermost. In addition, conjoined twin embryos form at very high frequencies in response to certain conditions of single or double centrifugation. Cytological analysis shows that the dorsal structures invariably form from the side(s) of the egg away from which vegetal cytoplasm was displaced. This is similar to the situation in the unperturbed egg, where the subcortical cytoplasm of the vegetal hemisphere rotates some 30° relative to the surface, and the dorsal structures form from the side of the egg away from which the subcortical cytoplasm moved. The displacements elicited by centrifugation probably substitute for the normal displacements brought about by the subcortical rotation. These and other data suggest that the subcortical rotation is a crucial step in the process of axis determination. The subcortical rotation is an autonomous activity of the activated egg, and can displace cytoplasm against gravity. I believe that the subcortical rotation will function normally at microgravity, and I expect that overall development and axis polarity at microgravity will be normal. This will be tested in spaceflight.

  7. Hydrodynamic drive of tubular centrifuges

    SciTech Connect

    Tsybul'nik, A.P.

    1986-07-01

    A drive has been developed for a tubular centrifuge having a 10 kW ASTs-10-504 high-frequency electric motor with a synchronous rotation speed of 15,000 rpm. Despite a few demerits, the drive met the basic production requirements; simplicity and reliability of design, admissable rotation speed, and explosion resistance. However, this drive for tubular centrifuges had to be abandoned because experimental prototypes of high-frequency motors were used for the industrial tests and lot production of such motors is not probable in the near future. Industrial tests of a new hydrodynamic drive were performed, and the schematic diagram is shown. The hydrodrive was tested during centrifuge operation with polyester lac. It was found that the hydodynamic drive is distinguished by operational reliability and easy serviceability, holds promise for increased centrifuge speed, ensures smooth start of the centrifuge and satisfactory stability of the rotor rotation speed in the steady regime, reliably protects the motor from overloading and is fully explosion-proof.

  8. Optimum design for LRE centrifugal pumps

    NASA Astrophysics Data System (ADS)

    Zhu, Zuchao; Zhang, Guoqian; Sun, Jiren

    1995-05-01

    We set up a mathematical model to predict low specific speed liquid rocket engine (LRE) centrifugal pump unit performance. Using the model in question, performance predictions were carried out for 10 types of LRE centrifugal pumps. Relative errors between experimental values and predicted values associated with efficiency and lift were all within 4%. Using the model in question, design optimization with efficiency as the target function was carried out on AM-7H and O pumps as well as AM-1R pumps and AM-50 pumps. Results clearly show that, with a presupposition of surety systems possessing high vapor corrosion characteristics, the efficiencies of these four types of pumps can be respectively raised 6.5%, 5.22%, 5.2%, and 4.41%.

  9. Centrifugal pump fuel system

    SciTech Connect

    McGlone, M.E.; Larkins, L.J.; Johnson, R.O.; Moeller, K.A.

    1993-06-22

    A centrifugal pump fuel system for an engine driven fuel pump for an aircraft gas turbine engine is described comprising: a centrifugal pump having at constant speed rising head/flow characteristic at low flows; a plumbing system receiving flow from the pump, and having at least one control valve located down stream of and defining a discrete volume of the plumbing system; a plumbing resonant frequency defined by the discrete volume, the geometry of the plumbing system, and the bulk modulus of the fuel; a pressure difference regulating valve located adjacent to the discharge of the pump, up stream of the vast majority of the discrete volume; and the frequency response of the regulating valve being significantly less than the frequency response of the plumbing system such that the response of the regulating valve is attenuated at the resonant frequency of the plumbing system.

  10. DEM simulation of granular flows in a centrifugal acceleration field

    NASA Astrophysics Data System (ADS)

    Cabrera, Miguel Angel; Peng, Chong; Wu, Wei

    2017-04-01

    The main purpose of mass-flow experimental models is abstracting distinctive features of natural granular flows, and allow its systematic study in the laboratory. In this process, particle size, space, time, and stress scales must be considered for the proper representation of specific phenomena [5]. One of the most challenging tasks in small scale models, is matching the range of stresses and strains among the particle and fluid media observed in a field event. Centrifuge modelling offers an alternative to upscale all gravity-driven processes, and it has been recently employed in the simulation of granular flows [1, 2, 3, 6, 7]. Centrifuge scaling principles are presented in Ref. [4], collecting a wide spectrum of static and dynamic models. However, for the case of kinematic processes, the non-uniformity of the centrifugal acceleration field plays a major role (i.e., Coriolis and inertial effects). In this work, we discuss a general formulation for the centrifugal acceleration field, implemented in a discrete element model framework (DEM), and validated with centrifuge experimental results. Conventional DEM simulations relate the volumetric forces as a function of the gravitational force Gp = mpg. However, in the local coordinate system of a rotating centrifuge model, the cylindrical centrifugal acceleration field needs to be included. In this rotating system, the centrifugal acceleration of a particle depends on the rotating speed of the centrifuge, as well as the position and speed of the particle in the rotating model. Therefore, we obtain the formulation of centrifugal acceleration field by coordinate transformation. The numerical model is validated with a series of centrifuge experiments of monodispersed glass beads, flowing down an inclined plane at different acceleration levels and slope angles. Further discussion leads to the numerical parameterization necessary for simulating equivalent granular flows under an augmented acceleration field. The premise of

  11. Centrifugal pyrocontactor

    DOEpatents

    Chow, L.S.; Leonard, R.A.

    1993-10-19

    A method is described for mixing and separating immiscible liquid salts and liquid metals in a centrifugal contractor. The method includes introducing the liquids into an annular mixing zone and intensely mixing the liquids using vertical vanes attached to a rotor cooperating with vertical baffles, a horizontal baffle, and bottom vanes attached to the contactor housing. The liquids enter the contactor in the range of 700-800 degrees Celsius. The liquids are separated in the rotor into a dense phase and a light phase which are discharged from the contactor. 6 figures.

  12. Centrifugal pyrocontactor

    DOEpatents

    Chow, Lorac S.; Leonard, Ralph A.

    1993-01-01

    A method for mixing and separating immiscible liquid salts and liquid metals in a centrifugal contractor. The method includes introducing the liquids into an annular mixing zone and intensely mixing the liquids using vertical vanes attached to a rotor cooperating with vertical baffles, a horizontal baffle, and bottom vanes attached to the contactor housing. The liquids enter the contactor in the range of 700-800 degrees Celsius. The liquids are separated in the rotor into a dense phase and a light phase which are discharged from the contactor.

  13. A vehicle-specific power approach to speed- and facility-specific emissions estimates for diesel transit buses.

    PubMed

    Zhai, Haibo; Frey, H Christopher; Rouphail, Nagui M

    2008-11-01

    Emissions during a trip often depend on transient vehicle dynamics that influence the instantaneous engine load. Vehicle specific power (VSP) is a proxy variable for engine load that has been shown to be highly correlated with emissions. This study estimates roadway link average emission rates for diesel-fueled transit buses based on link mean speeds, using newly defined VSP modes from data gathered by a portable emissions monitoring system. Speed profiles were categorized by facility type and mean travel speed, and stratified into discrete VSP modes. VSP modal average emission rates and the time spent in the corresponding VSP modes were then used to make aggregate estimates of total and average emission rates for a road link. The average emission rates were sensitive to link mean speed, but not to facility type. A recommendation is made regarding the implementation of link average emission rates in conjunction with transportation models for the purpose of estimating regional emissions for diesel transit buses.

  14. Liquid rocket engine centrifugal flow turbopumps. [design criteria

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Design criteria and recommended practices are discussed for the following configurations selected from the design sequence of a liquid rocket engine centrifugal flow turbopump: (1) pump performance including speed, efficiency, and flow range; (2) impeller; (3) housing; and (4) thrust balance system. Hydrodynamic, structural, and mechanical problems are addressed for the achievement of required pump performance within the constraints imposed by the engine/turbopump system. Materials and fabrication specifications are also discussed.

  15. Individual Differences in the Speed of Facial Emotion Recognition Show Little Specificity but Are Strongly Related with General Mental Speed: Psychometric, Neural and Genetic Evidence.

    PubMed

    Liu, Xinyang; Hildebrandt, Andrea; Recio, Guillermo; Sommer, Werner; Cai, Xinxia; Wilhelm, Oliver

    2017-01-01

    Facial identity and facial expression processing are crucial socio-emotional abilities but seem to show only limited psychometric uniqueness when the processing speed is considered in easy tasks. We applied a comprehensive measurement of processing speed and contrasted performance specificity in socio-emotional, social and non-social stimuli from an individual differences perspective. Performance in a multivariate task battery could be best modeled by a general speed factor and a first-order factor capturing some specific variance due to processing emotional facial expressions. We further tested equivalence of the relationships between speed factors and polymorphisms of dopamine and serotonin transporter genes. Results show that the speed factors are not only psychometrically equivalent but invariant in their relation with the Catechol-O-Methyl-Transferase (COMT) Val158Met polymorphism. However, the 5-HTTLPR/rs25531 serotonin polymorphism was related with the first-order factor of emotion perception speed, suggesting a specific genetic correlate of processing emotions. We further investigated the relationship between several components of event-related brain potentials with psychometric abilities, and tested emotion specific individual differences at the neurophysiological level. Results revealed swifter emotion perception abilities to go along with larger amplitudes of the P100 and the Early Posterior Negativity (EPN), when emotion processing was modeled on its own. However, after partialling out the shared variance of emotion perception speed with general processing speed-related abilities, brain-behavior relationships did not remain specific for emotion. Together, the present results suggest that speed abilities are strongly interrelated but show some specificity for emotion processing speed at the psychometric level. At both genetic and neurophysiological levels, emotion specificity depended on whether general cognition is taken into account or not. These

  16. Individual Differences in the Speed of Facial Emotion Recognition Show Little Specificity but Are Strongly Related with General Mental Speed: Psychometric, Neural and Genetic Evidence

    PubMed Central

    Liu, Xinyang; Hildebrandt, Andrea; Recio, Guillermo; Sommer, Werner; Cai, Xinxia; Wilhelm, Oliver

    2017-01-01

    Facial identity and facial expression processing are crucial socio-emotional abilities but seem to show only limited psychometric uniqueness when the processing speed is considered in easy tasks. We applied a comprehensive measurement of processing speed and contrasted performance specificity in socio-emotional, social and non-social stimuli from an individual differences perspective. Performance in a multivariate task battery could be best modeled by a general speed factor and a first-order factor capturing some specific variance due to processing emotional facial expressions. We further tested equivalence of the relationships between speed factors and polymorphisms of dopamine and serotonin transporter genes. Results show that the speed factors are not only psychometrically equivalent but invariant in their relation with the Catechol-O-Methyl-Transferase (COMT) Val158Met polymorphism. However, the 5-HTTLPR/rs25531 serotonin polymorphism was related with the first-order factor of emotion perception speed, suggesting a specific genetic correlate of processing emotions. We further investigated the relationship between several components of event-related brain potentials with psychometric abilities, and tested emotion specific individual differences at the neurophysiological level. Results revealed swifter emotion perception abilities to go along with larger amplitudes of the P100 and the Early Posterior Negativity (EPN), when emotion processing was modeled on its own. However, after partialling out the shared variance of emotion perception speed with general processing speed-related abilities, brain-behavior relationships did not remain specific for emotion. Together, the present results suggest that speed abilities are strongly interrelated but show some specificity for emotion processing speed at the psychometric level. At both genetic and neurophysiological levels, emotion specificity depended on whether general cognition is taken into account or not. These

  17. Centrifugation and the Manhattan Project

    NASA Astrophysics Data System (ADS)

    Reed, Cameron

    2009-05-01

    A study of U. S. Army Manhattan Engineer District documents reveals that consideration of centrifugation as a means of uranium enrichment during World War II was considerably more extensive than is commonly appreciated. By the time the centrifuge project was abandoned in early 1944 a full-scale prototype unit had been fabricated and tested at near-production speeds, enrichments of close to theoretically-expected levels had been demonstrated with pilot-plant units, and plans for production plants had been developed. This paper will review the history of this little-known aspect of the Project and examine the circumstances of how it came to be discontinued.

  18. Centrifugation and the Manhattan Project

    NASA Astrophysics Data System (ADS)

    Reed, Cameron

    2009-04-01

    A study of U. S. Army Manhattan Engineer District documents reveals that consideration of centrifugation as a means of uranium enrichment during World War II was considerably more extensive than is commonly appreciated. By the time the centrifuge project was abandoned in early 1944 a full-scale prototype unit had been fabricated and tested at near-production speeds, enrichments of close to theoretically-expected levels had been demonstrated with pilot-plant units, and plans for production plants had been developed. This paper will review the history of this little-known aspect of the Project and examine the circumstances of how it came to be discontinued.

  19. Effect of Rotational Speeds on the Cast Tube During Vertical Centrifugal Casting Process on Appearance, Microstructure, and Hardness Behavior for Al-2Si Alloy

    NASA Astrophysics Data System (ADS)

    Shailesh Rao, A.; Tattimani, Mahantesh S.; Rao, Shrikantha S.

    2015-04-01

    The flow of molten metal plays a crucial role in determining casting quality. During rotation of the mold, melt flow around its inner circumference determines the final configurations and properties of the cast tube. In this paper, Al-2Si alloy is cast in the vertical mold at the various rotational speeds of the mold. The uniform cylinder tube is formed at a rotational speed of 1000 rpm, while before and beyond this speed, irregular-shaped cast tube is formed. Finally, fine structured grain size with high hardness value is found in uniform cast tube compared with others.

  20. Specific binding of sup 125 I-rErythropoietin to Friend polycythemia virus-transformed erythroleukemia cells purified by centrifugal elutriation

    SciTech Connect

    Correa, P.N.; Bard, V.; Axelrad, A.A. )

    1990-01-01

    We have used countercurrent centrifugal elutriation (CCE) to determine the distribution of cells with respect to cell volume and buoyant density for an erythroleukemia cell line (JG6) transformed by the polycythemia strain of Friend virus (FV-P), and to determine the effect of inducing the cells to differentiate with dimethylsulfoxide (DMSO) on this distribution. CCE made it possible to obtain suspensions of modal JG6 populations virtually free of dead cells and uniform with respect to volume and buoyant density. These modal populations were assayed for specific binding of erythropoietin (Epo). Between 500 and 550 Epo receptors per cell were detected. These belonged to a single class having a dissociation constant of 0.36 nM. DMSO induction of differentiation of the JG6 cells had no effect on the number of Epo receptors expressed.

  1. Performance Measurements of a Low Specific Speed TurboClaw® Compressor

    NASA Astrophysics Data System (ADS)

    Parra, J.; Cattell, R.; Etemad, S.; Pullen, K. R.

    2015-08-01

    Low specific speed compressors have been historically based on positive displacement machines. Attempts to bring advantages of turbomachinery such as oil free, low parts counts, low cost of manufacture, and reliability to low flow rate applications have not been sparse, but the principle difficulty has always been that the conventional turbomachine design operates at ultra-high speed to deliver low volume flow rates. This is synonymous with low efficiency due to higher losses (windage, surface finish, and tip clearances). The innovative TurboClaw® design is a low specific speed turbomachinery with forward swept impeller geometry. It owes its high efficiency and operational stability to careful design of its nearly tangential forward swept blading and diffuser geometry.

  2. Effect of exercise and pump speed modulation on invasive hemodynamics in patients with centrifugal continuous-flow left ventricular assist devices.

    PubMed

    Muthiah, Kavitha; Robson, Desiree; Prichard, Roslyn; Walker, Robyn; Gupta, Sunil; Keogh, Anne M; Macdonald, Peter S; Woodard, John; Kotlyar, Eugene; Dhital, Kumud; Granger, Emily; Jansz, Paul; Spratt, Phillip; Hayward, Christopher S

    2015-04-01

    Continuous-flow left ventricular assist devices (CF-LVADs) improve functional capacity in patients with end-stage heart failure. Pump output can be increased by increased pump speed as well as changes in loading conditions. The effect of exercise on invasive hemodynamics was studied in two study protocols. The first examined exercise at fixed pump speed (n = 8) and the second with progressive pump speed increase (n = 11). Patients underwent simultaneous right-heart catheterization, mixed venous saturation, echocardiography and mean arterial pressure monitoring. Before exercise, a ramp speed study was performed in all patients. Patients then undertook symptom-limited supine bicycle exercise. Upward titration of pump speed at rest (by 11.6 ± 8.6% from baseline) increased pump flow from 5.3 ± 1.0 to 6.3 ± 1.0 liters/min (18.9% increase, p < 0.001) and decreased pulmonary capillary wedge pressure (PCWP; 13.6 ± 5.4 to 8.9 ± 4.1 mm Hg, p < 0.001). Exercise increased pump flow to a similar extent as pump speed change alone (to 6.2 ± 1.0 liters/min, p < 0.001), but resulted in increased right- and left-heart filling pressures (right atrial pressure [RAP]: 16.6 ± 7.5 mm Hg, p < 0.001; PCWP 24.8 ± 6.7 mm Hg, p < 0.001). Concomitant pump speed increase with exercise enhanced the pump flow increase (to 7.0 ± 1.4 liters/min, p < 0.001) in Protocol 2, but did not alleviate the increase in pre-load (RAP: 20.5 ± 8.0 mm Hg, p = 0.07; PCWP: 26.8 ± 12.7 mm Hg; p = 0.47). Serum lactate and NT-proBNP levels increased significantly with exercise. Pump flow increases with up-titration of pump speed and with exercise. Although increased pump speed decreases filling pressures at rest, the benefit is not seen with exercise despite concurrent up-titration of pump speed. Crown Copyright © 2015. Published by Elsevier Inc. All rights reserved.

  3. The influence of rotor type and centrifugation time on the yield and purity of extracellular vesicles

    PubMed Central

    Cvjetkovic, Aleksander; Lötvall, Jan; Lässer, Cecilia

    2014-01-01

    Background Extracellular vesicles (EV), the collective term for vesicles released from cells, consist of vesicle species ranging in size from 30 nm to 5 µm in diameter. These vesicles are most commonly isolated by differential centrifugations, which pellets particles based on their differential movement through the liquid medium in which they are immersed. Multiple parameters, including the utilization of different rotor types, can influence the yield and purity of isolated vesicles; however, the understanding of how these factors affect is limited. Materials and methods Here, we compare the influence of multiple centrifugation parameters, including the use of swinging bucket and fixed angle rotors, as well as different centrifugation times, for the isolation of the smallest EVs, “exosomes.” In particular, we determine the yields of exosomal RNA and protein, as well as the nature of the isolated vesicles and possible protein contamination with methods such as electron microscopy, western blot and flow cytometry. Results Our results show that application of a specific g-force or rotation speed by itself does not predict the ability of pelleting exosomes, and that prolonged centrifugation times can achieve greater yields of exosomal RNA and protein, whereas very long centrifugation times result in excessive protein concentrations in the exosome pellet. Conclusion In conclusion, rotor type, g-force and centrifugation times significantly influence exosome yield during centrifugation-based isolation procedures, and current commonly recommended isolation protocols may not be fully optimized for yield and purity of exosomes. PMID:24678386

  4. Marine Snow Aggregates: Size Specific Settling Speeds, Abundance, and Size Specific Ratios of Settling to Total Abundance of Aggregates

    NASA Astrophysics Data System (ADS)

    Diercks, Arne-Roland

    1995-01-01

    Determining in situ settling speeds, vertical profiles of total aggregate abundance, and the amount of settling aggregates as a ratio of the total aggregate abundance were the main objectives of this research. Aggregate abundance was determined with the MAGENUM (Marine AGgregate ENUMerator) camera system (modified after Honjo et al., 1984). Aggregate flux and settling speeds were determined with the MAFIA (Marine Aggregate Flux Investigation Apparatus), a combination of aggregate camera system and sediment trap. In situ settling speed data (MAFIA) of aggregates from the central Black Sea and the northern Gulf of Mexico were analyzed for five size classes of aggregates, showed a wide variation in settling speeds in the individual size classes. Neither environment studied showed a positive correlation of aggregate settling speed to aggregate diameter, indicating that particle density was the more important factor in determining the aggregates settling speed. Marine snow abundance data from the Equatorial Pacific were analyzed using discrete fourier transform analysis to estimate size specific settling speeds of aggregates ranging from 1 to 10 mm spherical diameter. Settling speeds of aggregates followed the exponential function: rm Settling^eed = 22.3 e^ {(0.147 {aggregate diameter [ mm]})} (r^2 of 0.65). The ratio of the abundance of settling aggregates to the total abundance of aggregates, termed S-ratio, was calculated from MAFIA data from the central Black Sea and the northern Gulf of Mexico for six size classes of aggregates. In both locations ratios greater than one were calculated. This suggested that the MAGENUM did not record the total aggregate abundance, as assumed, but only a fraction of the aggregates present in the water column. The abundance of fine particles was compared to profiles of abundance of marine snow aggregates. Interactions were qualitatively discussed between these two size classes. In most profiles aggregates and fine particles showed

  5. Can reading-specific training stimuli improve the effect of perceptual learning on peripheral reading speed?

    PubMed Central

    Bernard, Jean-Baptiste; Arunkumar, Amit; Chung, Susana T.L.

    2012-01-01

    In a previous study, Chung, Legge & Cheung (2004) showed that training using repeated presentation of trigrams (sequences of three random letters) resulted in an increase in the size of the visual span (number of letters recognized in a glance) and reading speed in the normal periphery. In this study, we asked whether we could optimize the benefit of trigram training on reading speed by using trigrams more specific to the reading task (i.e. trigrams frequently used in the English language) and presenting them according to their frequencies of occurrence in normal English usage and observers’ performance. Averaged across seven observers, our training paradigm (four days of training) increased the size of the visual span by 6.44 bits, with an accompanied 63.6% increase in the maximum reading speed, compared with the values before training. However, these benefits were not statistically different from those of Chung et al (2004) using a random-trigram training paradigm. Our findings confirm the possibility of increasing the size of the visual span and reading speed in the normal periphery with perceptual learning, and suggest that the benefits of training on letter recognition and maximum reading speed may not be linked to the types of letter strings presented during training. PMID:22750053

  6. Can reading-specific training stimuli improve the effect of perceptual learning on peripheral reading speed?

    PubMed

    Bernard, Jean-Baptiste; Arunkumar, Amit; Chung, Susana T L

    2012-08-01

    In a previous study, Chung, Legge, and Cheung (2004) showed that training using repeated presentation of trigrams (sequences of three random letters) resulted in an increase in the size of the visual span (number of letters recognized in a glance) and reading speed in the normal periphery. In this study, we asked whether we could optimize the benefit of trigram training on reading speed by using trigrams more specific to the reading task (i.e., trigrams frequently used in the English language) and presenting them according to their frequencies of occurrence in normal English usage and observers' performance. Averaged across seven observers, our training paradigm (4 days of training) increased the size of the visual span by 6.44 bits, with an accompanied 63.6% increase in the maximum reading speed, compared with the values before training. However, these benefits were not statistically different from those of Chung, Legge, and Cheung (2004) using a random-trigram training paradigm. Our findings confirm the possibility of increasing the size of the visual span and reading speed in the normal periphery with perceptual learning, and suggest that the benefits of training on letter recognition and maximum reading speed may not be linked to the types of letter strings presented during training.

  7. Assessing specific deterrence effects of increased speeding penalties using four measures of recidivism.

    PubMed

    Watson, B; Siskind, V; Fleiter, J J; Watson, A; Soole, D

    2015-11-01

    Traffic law enforcement sanctions can impact on road user behaviour through general and specific deterrence mechanisms. The manner in which specific deterrence can influence recidivist behaviour can be conceptualised in different ways. While any reduction in speeding will have road safety benefits, the ways in which a 'reduction' is determined deserves greater methodological attention and has implications for countermeasure evaluation more generally. The primary aim of this research was to assess the specific deterrent impact of penalty increases for speeding offences in Queensland, Australia, in 2003 on two cohorts of drivers detected for speeding prior to and after the penalty changes were investigated. Since the literature is relatively silent on how to assess recidivism in the speeding context, the secondary research aim was to contribute to the literature regarding ways to conceptualise and measure specific deterrence in the speeding context. We propose a novel way of operationalising four measures which reflect different ways in which a specific deterrence effect could be conceptualised: (1) the proportion of offenders who re-offended in the follow up period; (2) the overall frequency of re-offending in the follow up period; (3) the length of delay to re-offence among those who re-offended; and (4) the average number of re-offences during the follow up period among those who re-offended. Consistent with expectations, results suggested an absolute deterrent effect of penalty changes, as evidenced by significant reductions in the proportion of drivers who re-offended and the overall frequency of re-offending, although effect sizes were small. Contrary to expectations, however, there was no evidence of a marginal specific deterrent effect among those who re-offended, with a significant reduction in the length of time to re-offence and no significant change in the average number of offences committed. Additional exploratory analyses investigating potential

  8. Vacuum chamber-free centrifuge with magnetic bearings.

    PubMed

    Park, Cheol Hoon; Kim, Soohyun; Kim, Kyung-Soo

    2013-09-01

    Centrifuges are devices that separate particles of different densities and sizes through the application of a centrifugal force. If a centrifuge could be operated under atmospheric conditions, all vacuum-related components such as the vacuum chamber, vacuum pump, diffusion pump, and sealing could be removed from a conventional centrifuge system. The design and manufacturing procedure for centrifuges could then be greatly simplified to facilitate the production of lightweight centrifuge systems of smaller volume. Furthermore, the maintenance costs incurred owing to wear and tear due to conventional ball bearings would be eliminated. In this study, we describe a novel vacuum chamber-free centrifuge supported by magnetic bearings. We demonstrate the feasibility of the vacuum chamber-free centrifuge by presenting experimental results that verify its high-speed support capability and motoring power capacity.

  9. [Galileo and centrifugal force].

    PubMed

    Vilain, Christiane

    This work intends to focus on Galileo's study of what is now called "centrifugal force," within the framework of the Second Day of his Dialogo written in 1632, rather than on the previously published commentaries on the topic. Galileo proposes three geometrical demonstrations in order to prove that gravity will always overcome centrifugalforce, and that the potential rotation of the Earth, whatever its speed, cannot in any case project objects beyond it. Each of these demonstrations must consequently contain an error and it has seemed to us that the first one had not been understood up until now. Our analysis offers an opportunity to return to Galileo's geometrical representation of dynamical questions; actually, we get an insight into the sophistication of Galileo's practices more than into his mistakes. Our second point, concerning the historiography of the problem, shows an evolution from anachronic critics to more contextual considerations, in the course of the second half of the twentieth century.

  10. Safety aspects of gas centrifuge enrichment plants

    SciTech Connect

    Hansen, A.H.

    1987-01-01

    Uranium enrichment by gas centrifuge is a commercially proven, viable technology. Gas centrifuge enrichment plant operations pose hazards that are also found in other industries as well as unique hazards as a result of processing and handling uranium hexafluoride and the handling of enriched uranium. Hazards also found in other industries included those posed by the use of high-speed rotating equipment and equipment handling by use of heavy-duty cranes. Hazards from high-speed rotating equipment are associated with the operation of the gas centrifuges themselves and with the operation of the uranium hexafluoride compressors in the tail withdrawal system. These and related hazards are discussed. It is included that commercial gas centrifuge enrichment plants have been designed to operate safely.

  11. Power transmission mechanism equipped with fluid and centrifugal clutch

    SciTech Connect

    Tamura, K.; Takeshita, S.; Fukunaga, T.

    1986-12-30

    This patent describes a power transmission mechanism equipped with a fluid coupling, an input shaft thereof interconnected to a power source being interconnected through the fluid coupling to an output shaft, and the output shaft being interconnected to a forward-rearward changeover mechanism including a speed changer. It is characterized in that the fluid coupling includes a shell, an impeller in the shell and a centrifugal clutch means in the shell for engaging the impeller and for driving the impeller when the shell is rotated by the input shaft at a speed above idle speed and for disengaging the impeller and the driving of the impeller when the shell is rotated by the input shaft at the idle speed. A turbine is included in the shell for standing idle in the shell when the centrifugal clutch means is disengaged and for drive by the impeller when the centrifugal clutch means is engaged and for driving the output shaft. The centrifugal clutch means comprises a support member fixed to the shell, a centrifugal shoe mounted on the support member for radial movement outwardly of the support member by centrifugal force and radial movement inwardly toward the support member. It also comprises spring means for moving the shoe inwardly toward the support member when the shell is rotated at idle speed, a cylindrical casing fixed to the impeller radially outward from the shoe and having an engaging surface for engagement by the centrifugal shoe when the shell is rotated at a speed above idle speed and the centrifugal shoe is moved radially outward by centrifugal force. The forward-rearward changeover mechanism, including the speed changer, is driven by the turbine when the centrifugal clutch means is engaged with the engaging surface and standing idle when the centrifugal clutch means is disengaged from the engaging surface and the turbine is standing idle.

  12. IMMUNOLOGICAL SPECIFICITY OF MATERIAL SEDIMENTABLE AT HIGH SPEED PRESENT IN NORMAL AND TUMOR TISSUES

    PubMed Central

    Furth, Jacob; Kabat, Elvin A.

    1941-01-01

    Materials sedimentable at high speed (approximately 27,000 R.P.M.) were found in all normal and neoplastic tissues studied. They are carriers of the Forssman antigen and of the Wassermann hapten. These heavy materials exhibit species, organ, and individual specificity and produce several antibodies which can be demonstrated by absorption tests. Heavy materials from chicken sarcoma and chicken spleen could not be distinguished by complement fixation tests. PMID:19871132

  13. Experiences with the hydraulic design of the high specific speed Francis turbine

    NASA Astrophysics Data System (ADS)

    Obrovsky, J.; Zouhar, J.

    2014-03-01

    The high specific speed Francis turbine is still suitable alternative for refurbishment of older hydro power plants with lower heads and worse cavitation conditions. In the paper the design process of such kind of turbine together with the results comparison of homological model tests performed in hydraulic laboratory of ČKD Blansko Engineering is introduced. The turbine runner was designed using the optimization algorithm and considering the high specific speed hydraulic profile. It means that hydraulic profiles of the spiral case, the distributor and the draft tube were used from a Kaplan turbine. The optimization was done as the automatic cycle and was based on a simplex optimization method as well as on a genetic algorithm. The number of blades is shown as the parameter which changes the resulting specific speed of the turbine between ns=425 to 455 together with the cavitation characteristics. Minimizing of cavitation on the blade surface as well as on the inlet edge of the runner blade was taken into account during the design process. The results of CFD analyses as well as the model tests are mentioned in the paper.

  14. Testing of pyrochemical centrifugal contactors

    SciTech Connect

    Chow, L.S.; Carls, E.L.; Basco, J.K.; Johnson, T.R.

    1996-08-01

    A centrifugal contactor that performs oxidation and reduction exchange reactions between molten metals and salts at 500 degrees Centigrade has been tested successfully at Argonne National Laboratory (ANL). The design is based on contactors for aqueous- organic systems operation near room temperature. In tests to demonstrate the performance of the pyrocontactor, cadmium and LICl- KCl eutectic salt were the immiscible solvent phases, and rare earths were the distributing solutes. The tests showed that the pyrocontactor mixed and separated the phases well, with stage efficiencies approaching 99% at rotor speeds near 2700 rpm. The contactor ran smoothly and reliably over the entire range of speeds that was tested.

  15. Centrifugal reciprocating compressor

    NASA Technical Reports Server (NTRS)

    High, W. H.

    1980-01-01

    Efficient compressor uses centrifugal force to compress gas. System incorporates two coupled dc motors, each driving separate centrifugal reciprocating-compressor assembly. Motors are synchronized to accelerate and decelerate alternately.

  16. Solid deuterium centrifuge pellet injector

    SciTech Connect

    Foster, C.A.

    1982-01-01

    Pellet injectors are needed to fuel long pulse tokamak plasmas and other magnetic confinement devices. For this purpose, an apparatus has been developed that forms 1.3-mm-diam pellets of frozen deuterium at a rate of 40 pellets per second and accelerates them to a speed of 1 km/s. Pellets are formed by extruding a billet of solidified deuterium through a 1.3-mm-diam nozzle at a speed of 5 cm/s. The extruding deuterium is chopped with a razor knife, forming 1.3-mm right circular cylinders of solid deuterium. The pellets are accelerated by synchronously injecting them into a high speed rotating arbor containing a guide track, which carries them from a point near the center of rotation to the periphery. The pellets leave the wheel after 150/sup 0/ of rotation at double the tip speed. The centrifuge is formed in the shape of a centrifugal catenary and is constructed of high strength KEVLAR/epoxy composite. This arbon has been spin-tested to a tip speed of 1 km/s.

  17. CENTRIFUGE END CAP

    DOEpatents

    Beams, J.W.; Snoddy, L.B.

    1960-08-01

    An end cap for ultra-gas centrifuges is designed to impart or remove angular momentum to or from the gas and to bring the entering gas to the temperature of the gas inside the centrifuge. The end cap is provided with slots or fins for adjusting the temperature and the angular momentum of the entering gas to the temperature and momentum of the gas in the centrifuge and is constructed to introduce both the inner and the peripheral stream into the centrifuge.

  18. Investigation on internal flow of draft tube at overload condition in low specific speed Francis turbine

    NASA Astrophysics Data System (ADS)

    Tamura, Yuta; Tani, Kiyohito

    2016-11-01

    The cavitating vortices causes the unsteady phenomena like the pressure fluctuation, the noise and the vibration in the draft tube at the overload condition which is the far operating point from the design point. Because the full load was normally near the design point, there were few troubles due to cavitating vortices at the full load. Today, however, the design point is sometimes set to lower load to achieve the high efficiency from the partial load to the full load in low specific speed Francis turbines, which have good performance to a change in a discharge. Then, the full load is relatively further from the design point. As the result, the potential for the cavitating vortices at the full load is increased. To control of the unsteady phenomena at the full load, the study focused on the cavitating vortices at the overload condition is important. This paper presents the unsteady behavior of the cavitating vortices at the overload condition with the scaled model of specific speed NQE=0.083. On the experimental approach, the pressure pulsation in the upper draft tube was measured and the unsteady behavior of cavitating vortices was taken movies with a high speed camera. On the numerical approach, Computational Fluid Dynamics (CFD) adopting a two-phase unsteady analysis was carried out. The pressure fluctuation and the velocity distribution of two runners, an original and a newly designed, were compared.

  19. Action-specific effects in a social context: others' abilities influence perceived speed.

    PubMed

    Witt, Jessica K; Sugovic, Mila; Taylor, J Eric T

    2012-06-01

    According to the action-specific account of perception, perceivers see the environment relative to their ability to perform the intended action. For example, in a modified version of the computer game Pong, balls that were easier to block looked to be moving slower than balls that were more difficult to block (Witt & Sugovic, 2010). It is unknown, however, if perception can be influenced by another person's abilities. In the current experiment, we examined whether another person's ability to block a ball influenced the observer's perception of ball speed. Participants played and observed others play the modified version of Pong where the task was to successfully block the ball with paddles that varied in size, and both the actor and observer estimated the speed of the ball. The results showed that both judged the ball to be moving faster when it was harder to block. However, the same effect of difficulty on speed estimates was not found when observers watched a computer play, suggesting the effect is specific to people and not to the task. These studies suggest that the environment can be perceived relative to another person's abilities.

  20. Effects of domain-specific exercise load on speed and accuracy of a domain-specific perceptual-cognitive task.

    PubMed

    Schapschröer, M; Baker, J; Schorer, J

    2016-08-01

    In the context of perceptual-cognitive expertise it is important to know whether physiological loads influence perceptual-cognitive performance. This study examined whether a handball specific physical exercise load influenced participants' speed and accuracy in a flicker task. At rest and during a specific interval exercise of 86.5-90% HRmax, 35 participants (experts: n=8, advanced: n=13, novices, n=14) performed a handball specific flicker task with two types of patterns (structured and unstructured). For reaction time, results revealed moderate effect sizes for group, with experts reacting faster than advanced and advanced reacting faster than novices, and for structure, with structured videos being performed faster than unstructured ones. A significant interaction for structure×group was also found, with experts and advanced players faster for structured videos, and novices faster for unstructured videos. For accuracy, significant main effects were found for structure with structured videos solved more accurately. A significant interaction for structure×group was revealed, with experts and advanced more accurate for structured scenes and novices more accurate for unstructured scenes. A significant interaction was also found for condition×structure; at rest, unstructured and structured scenes were performed with the same accuracy while under physical exercise, structured scenes were solved more accurately. No other interactions were found. These results were somewhat surprising given previous work in this area, although the impact of a specific physical exercise on a specific perceptual-cognitive task may be different from those tested generally.

  1. CENTRIFUGAL MEMBRANE FILTRATION

    SciTech Connect

    Daniel J. Stepan; Bradley G. Stevens; Melanie D. Hetland

    1999-10-01

    The overall project consists of several integrated research phases related to the applicability, continued development, demonstration, and commercialization of the SpinTek centrifugal membrane filtration process. Work performed during this reporting period consisted of Phase 2 evaluation of the SpinTek centrifugal membrane filtration technology and Phase 3, Technology Partnering. During Phase 1 testing conducted at the EERC using the SpinTek ST-IIL unit operating on a surrogate tank waste, a solids cake developed on the membrane surface. The solids cake was observed where linear membrane velocities were less than 17.5 ft/s and reduced the unobstructed membrane surface area up to 25%, reducing overall filtration performance. The primary goal of the Phase 2 research effort was to enhance filtration performance through the development and testing of alternative turbulence promoter designs. The turbulence promoters were designed to generate a shear force across the entire membrane surface sufficient to maintain a self-cleaning membrane capability and improve filtration efficiency and long-term performance. Specific Phase 2 research activities included the following: System modifications to accommodate an 11-in.-diameter, two-disk rotating membrane assembly; Development and fabrication of alternative turbulence promoter designs; Testing and evaluation of the existing and alternative turbulence promoters under selected operating conditions using a statistically designed test matrix; and Data reduction and analysis; The objective of Phase 3 research was to demonstrate the effectiveness of SpinTek's centrifugal membrane filtration as a pretreatment to remove suspended solids from a liquid waste upstream of 3M's WWL cartridge technology for the selective removal of technetium (Tc).

  2. Active pneumatic control of centrifugal microfluidic flows for lab-on-a-chip applications.

    PubMed

    Clime, Liviu; Brassard, Daniel; Geissler, Matthias; Veres, Teodor

    2015-06-07

    This paper reports a novel method of controlling liquid motion on a centrifugal microfluidic platform based on the integration of a regulated pressure pump and a programmable electromechanical valving system. We demonstrate accurate control over the displacement of liquids within the system by pressurizing simultaneously multiple ports of the microfluidic device while the platform is rotating at high speed. Compared to classical centrifugal microfluidic platforms where liquids are solely driven by centrifugal and capillary forces, the method presented herein adds a new degree of freedom for fluidic manipulation, which represents a paradigm change in centrifugal microfluidics. We first demonstrate how various core microfluidic functions such as valving, switching, and reverse pumping (i.e., against the centrifugal field) can be easily achieved by programming the pressures applied at dedicated access ports of the microfluidic device. We then show, for the first time, that the combination of centrifugal force and active pneumatic pumping offers the possibility of mixing fluids rapidly (~0.1 s) and efficiently based on the creation of air bubbles at the bottom of a microfluidic reservoir. Finally, the suitability of the developed platform for performing complex bioanalytical assays in an automated fashion is demonstrated in a DNA harvesting experiment where recovery rates of about 70% were systematically achieved. The proposed concept offers the interesting prospect to decouple basic microfluidic functions from specific material properties, channel dimensions and fabrication tolerances, surface treatments, or on-chip active components, thus promoting integration of complex assays on simple and low-cost microfluidic cartridges.

  3. Research on energy conversion mechanism of a screw centrifugal pump under the water

    NASA Astrophysics Data System (ADS)

    Quan, H.; Li, R. N.; Su, Q. M.; Han, W.; Cheng, X. R.; Shen, Z. J.

    2013-12-01

    In order to research screw centrifugal pump impeller power capability and energy conversion mechanism, we used Navier-Stokes equation and standard k-ε equation turbulence model on the basis of the Euler equations to carry out screw centrifugal pump internal flow numerical simulation. This was explored by simulating specific design conditions; the medium is water, variation of speed and pressure of flow filed under the action of the impeller, and the screw centrifugal impeller shroud line and wheel line segment take monitoring sites. The monitoring points are between dynamic head and static head change to analyze the energy conversion capability along the impeller corners of screw centrifugal pump. The results show that the energy of fluid of the screw centrifugal pump is provided by spiral segment, the spiral segment in front of the impeller has played a multi-level role, it has significant reference value to research the energy conversion mechanism of screw centrifugal pump under solid-liquid two phase.

  4. Design of a centrifugal blood pump: Heart Turcica Centrifugal.

    PubMed

    Demir, Onur; Biyikli, Emre; Lazoglu, Ismail; Kucukaksu, Suha

    2011-07-01

    A prototype of a new implantable centrifugal blood pump system named Heart Turcica Centrifugal (HTC) was developed as a left ventricular assist device (LVAD) for the treatment of end-stage cardiac failure. In the development of HTC, effects of blade height and volute tongue profiles on the hydraulic and hemolytic performances of the pump were investigated. As a result, the prototype was manufactured using the best blade height and volute tongue profiles. Performance of the prototype model was experimentally evaluated in a closed-loop flow system using water as the medium. The hydraulic performance requirement of an LVAD (5 L/min flow rate against a pressure difference of 100 mm Hg) was attained at 2800 rpm rotational speed.

  5. Gas centrifuge purge method

    DOEpatents

    Theurich, Gordon R.

    1976-01-01

    1. In a method of separating isotopes in a high speed gas centrifuge wherein a vertically oriented cylindrical rotor bowl is adapted to rotate about its axis within an evacuated chamber, and wherein an annular molecular pump having an intake end and a discharge end encircles the uppermost portion of said rotor bowl, said molecular pump being attached along its periphery in a leak-tight manner to said evacuated chamber, and wherein end cap closure means are affixed to the upper end of said rotor bowl, and a process gas withdrawal and insertion system enters said bowl through said end cap closure means, said evacuated chamber, molecular pump and end cap defining an upper zone at the discharge end of said molecular pump, said evacuated chamber, molecular pump and rotor bowl defining a lower annular zone at the intake end of said molecular pump, a method for removing gases from said upper and lower zones during centrifuge operation with a minimum loss of process gas from said rotor bowl, comprising, in combination: continuously measuring the pressure in said upper zone, pumping gas from said lower zone from the time the pressure in said upper zone equals a first preselected value until the pressure in said upper zone is equal to a second preselected value, said first preselected value being greater than said second preselected value, and continuously pumping gas from said upper zone from the time the pressure in said upper zone equals a third preselected value until the pressure in said upper zone is equal to a fourth preselected value, said third preselected value being greater than said first, second and fourth preselected values.

  6. Unshrouded Centrifugal Turbopump Impeller

    NASA Technical Reports Server (NTRS)

    Prueger, George; Williams, Morgan; Chen, Wei; Paris, John; Stewart, Eric; Williams, Robert

    1999-01-01

    The ratio of rocket engine thrust to weight is a limiting constraint in placing more payload into orbit at a low cost. A key component of an engine's overall weight is the turbopump weight, Reducing the turbopump weight can result in significant engine weight reduction and hence, increased delivered payload. There are two main types of pumps: centrifugal and axial pumps. These types of pumps can be further sub-divided into those with shrouds and those without shrouds (unshrouded pumps). Centrifugal pumps can achieve the same pump discharge pressure as an axial pump and it requires fewer pump stages and lower pump weight than an axial pump. Also, with unshrouded centrifugal pumps (impeller), the number of stages and weight can be further reduced. However. there are several issues with regard to using an unshrouded impeller: 1) there is a pump performance penalty due to the front open face recirculation flow; 2) there is a potential pump axial thrust problem from the unbalanced front open face and the back shroud face; and, 3) since test data is very linu'ted for this configuration, there is uncertainty in the magnitude and phase of the rotordynamics forces due to the front impeller passage. The purpose of the paper is to discuss the design of an unshrouded impeller and to examine the design's hydrodynamic performance, axial thrust, and rotordynamics performance. The design methodology will also be discussed. This work will help provide some guidelines for unshrouded impeller design. In particular, the paper will discuss the design of three unshrouded impellers - one with 5 full and 5 partial blades (5+5). one with 6+6 blades and one with 8+8 blades. One of these designs will be selected for actual fabrication and flow test. Computational fluid dynamics (CFD) is used to help design and optimize the unshrouded impeller. The relative pump performance penalty is assessed by comparing the CFD results of the unshrouded impeller with the equivalent shrouded impeller for a

  7. [Rapid centrifugation assay standarization for dengue virus isolation].

    PubMed

    Palomino, Miryam; Gutierrez, Victoria; Salas, Ramses

    2010-03-01

    The plate centrifugation assay was standardized for dengue virus isolation from serum samples. C6/36-HT cells were used determining the optimal values for centrifugation spin speed, inoculum, sera dilution, and incubation time. Then, 22 positive serum samples with viral isolation and viral strains of the four reference dengue virus serotypes were tested simultaneously by the standardized plate centrifugation method and the conventional tube culture. The isolations were typified by indirect immunofluorescent test using monoclonal antibodies. The plate centrifugation method was optimized to 200 μL of inoculum, dilution of sera 1/20, centrifugation speed at 1600 rpm/30 min, and sensitivity of 95,5% after 5 days post-inoculation. We concluded that the plate centrifugation method increased dengue virus isolation, with a significant reduction of the time of isolation for dengue virus.

  8. Centrifuge advances using HTS magnetic bearings

    NASA Astrophysics Data System (ADS)

    Werfel, F. N.; Flögel-Delor, U.; Rothfeld, R.; Wippich, D.; Riedel, T.

    2001-05-01

    Passive magnetic bearings are of increasing technical interest. We performed experiments with centrifugal rotors to analyze gyroscopic forces in terms imbalance, rotor elasticity and damping. Centrifuge rotors need to be operated soft and stable without whirling the sediments. In order to evaluate optimal parameters critical and resonance behaviors are investigated. Eccentricities up 2 mm are safely passed by accelerating test wheels. In a simple model we describe the effect of passing critical rotational speeds. Measurements of bearing properties and wheel performance are presented. We have constructed a first prototype centrifuge designed with a HTS double bearing which operates a titanium rotor safely up to 30 000 rpm. A 15 W Stirling cooler serves cryogenics of the YBCO stators. From the experiments design guidelines for centrifugal applications with HTS bearings are given.

  9. Gender-specific influences of balance, speed, and power on agility performance.

    PubMed

    Sekulic, Damir; Spasic, Miodrag; Mirkov, Dragan; Cavar, Mile; Sattler, Tine

    2013-03-01

    The quick change of direction (i.e., agility) is an important athletic ability in numerous sports. Because of the diverse and therefore hardly predictable manifestations of agility in sports, studies noted that the improvement in speed, power, and balance should result in an improvement of agility. However, there is evident lack of data regarding the influence of potential predictors on different agility manifestations. The aim of this study was to determine the gender-specific influence of speed, power, and balance on different agility tests. A total of 32 college-aged male athletes and 31 college-aged female athletes (age 20.02 ± 1.89 years) participated in this study. The subjects were mostly involved in team sports (soccer, team handball, basketball, and volleyball; 80% of men, and 75% of women), martial arts, gymnastics, and dance. Anthropometric variables consisted of body height, body weight, and the body mass index. Five agility tests were used: a t-test (T-TEST), zig-zag test, 20-yard shuttle test, agility test with a 180-degree turn, and forward-backward running agility test (FWDBWD). Other tests included 1 jumping ability power test (squat jump, SQJ), 2 balance tests to determine the overall stability index and an overall limit of stability score (both measured by Biodex Balance System), and 2 running speed tests using a straight sprint for 10 and 20 m (S10 and S20, respectively). A reliability analysis showed that all the agility tests were reliable. Multiple regression and correlation analysis found speed and power (among women), and balance (among men), as most significant predictors of agility. The highest Pearson's correlation in both genders is found between the results of the FWDBWD and S10M tests (0.77 and 0.81 for men and women, respectively; p < 0.05). Power, measured using the SQJ, is significantly (p < 0.05) related to FWDBWD and T-TEST results but only for women (-0.44; -0.41). The balance measures were significantly related to the agility

  10. Effect of specific versus variable practice upon overhead throwing speed in children.

    PubMed

    van den Tillaar, Roland; Marques, Mário C

    2013-06-01

    This study compared the effect of practice throwing with specific weights (specificity principle) or with variable weights (variability of practice) for a short practice period in children. Primary school children (N = 41; M age = 7.7 yr., SD = 0.5) were randomly divided into three homogenous groups. The first two groups used specific overhead throwing practice: throws with a soccer ball or 1 kg balls, while the third group used variable practice with 0.35, 0.45, 0.5, and 1 kg balls. All groups trained twice per week for six weeks. The same workload per session between the three groups varied from 24 throws (1 kg practice group) to 43 throws (soccer ball practice group). Throwing speed and distance with different balls was measured before and after the practice period. Statistically significant increases in performance in all three practice groups were found with no significant differences between groups. The results indicate that both specific and variable practice of throwing in children lead to increases in performance. However, it seems that the increased workload (practice) is a more important factor than the type of practice (specific or variable) in enhancing performance in children.

  11. Effect of interactions between bubbles and graphite particles in copper alloy melts on microstructure formed during centrifugal casting. Part 1: Theoretical analysis

    SciTech Connect

    Kim, J.K.; Rohatgi, P.K.

    1999-06-01

    Frequently, particles get associated with gas bubbles in a melt and their interaction influences the final distribution of particles and porosity in the casting. An analytical model for the separation of a particle from a bubble in melts containing dispersed particles and bubbles is proposed. During centrifugal casting of alloys containing dispersed particles, both the particles and gas bubbles present in the melt move with the centrifugal forces. Using the force balance between surface tension and net centrifugal forces (centrifugal force minus buoyancy force), the critical rotational speed of the mold for the separation of the particles and the bubbles during centrifugal casting is calculated. The critical rotational speed of the mold to separate the particle from the bubble is lower for a small particle attached to a larger bubble, as compared to the case when a large particle is attached to a smaller bubble. For a given bubble size, the critical rotational speed of the mold to separate the bubble from the particle decreases with increasing particle size. For the specific case of spherical 5-{micro}m radius graphite particles dispersed in copper alloy melt, it was found that even at a low semiapical angle of about 9 deg, the critical rotational speed needs to be around 5000 rpm for a bubble size of 500-{micro}m radius and 0.09-m-diameter mold. The rotational speed decreases to 1000 rpm when the graphite particle radius increases to 100 {micro}m for the same bubble size in copper alloy melt.

  12. Visual tracking speed is related to basketball-specific measures of performance in NBA players.

    PubMed

    Mangine, Gerald T; Hoffman, Jay R; Wells, Adam J; Gonzalez, Adam M; Rogowski, Joseph P; Townsend, Jeremy R; Jajtner, Adam R; Beyer, Kyle S; Bohner, Jonathan D; Pruna, Gabriel J; Fragala, Maren S; Stout, Jeffrey R

    2014-09-01

    The purpose of this study was to determine the relationship between visual tracking speed (VTS) and reaction time (RT) on basketball-specific measures of performance. Twelve professional basketball players were tested before the 2012-13 season. Visual tracking speed was obtained from 1 core session (20 trials) of the multiple object tracking test, whereas RT was measured by fixed- and variable-region choice reaction tests, using a light-based testing device. Performance in VTS and RT was compared with basketball-specific measures of performance (assists [AST]; turnovers [TO]; assist-to-turnover ratio [AST/TO]; steals [STL]) during the regular basketball season. All performance measures were reported per 100 minutes played. Performance differences between backcourt (guards; n = 5) and frontcourt (forward/centers; n = 7) positions were also examined. Relationships were most likely present between VTS and AST (r = 0.78; p < 0.003), STL (r = 0.77; p < 0.003), and AST/TO (r = 0.78; p < 0.003), whereas a likely relationship was also observed with TO (r = 0.49; p < 0.109). Reaction time was not related to any of the basketball-specific performance measures. Backcourt players were most likely to outperform frontcourt players in AST and very likely to do so for VTS, TO, and AST/TO. In conclusion, VTS seems to be related to a basketball player's ability to see and respond to various stimuli on the basketball court that results in more positive plays as reflected by greater number of AST and STL and lower turnovers.

  13. Effect of particle size on the performance of batchwise centrifugal filtration.

    PubMed

    Hwang, K J

    2001-01-01

    The effect of particle size distribution on the performance of batchwise centrifugal filtration is studied. By analyzing the velocity of particles in a filter, a numerical program is designed for simulating the migration and deposition of particles. The particle size distributions and the average specific filtration resistances of cake are then estimated under various rotating speeds of the centrifuge. A large deviation of particle concentration profiles in the filter chamber will occur if the particle size distribution is not taken into consideration. A more heterogeneous cake will form under a lower rotating speed due to the sedimentation effect of particles. The predicted results of particle size distribution and average specific filtration resistance of cake agree well with the available experimental data.

  14. Optimization of Centrifugal Pump Characteristic Dimensions for Mechanical Circulatory Support Devices.

    PubMed

    Korakianitis, Theodosios; Rezaienia, Mohammad A; Paul, Gordon M; Rahideh, Akbar; Rothman, Martin T; Mozafari, Sahand

    2016-01-01

    The application of artificial mechanical pumps as heart assist devices impose power and size limitations on the pumping mechanism, and therefore requires careful optimization of pump characteristics. Typically new pumps are designed by relying on the performance of other previously designed pumps of known performance using concepts of fluid dynamic similarity. Such data are readily available for industrial pumps, which operate in Reynolds numbers region of 10. Heart assist pumps operate in Reynolds numbers of 10. There are few data available for the design of centrifugal pumps in this characteristic range. This article develops specific speed versus specific diameter graphs suitable for the design and optimization of these smaller centrifugal pumps concentrating in dimensions suitable for ventricular assist devices (VADs) and mechanical circulatory support (MCS) devices. A combination of experimental and numerical techniques was used to measure and analyze the performance of 100 optimized pumps designed for this application. The data are presented in the traditional Cordier diagram of nondimensional specific speed versus specific diameter. Using these data, nine efficient designs were selected to be manufactured and tested in different operating conditions of flow, pressure, and rotational speed. The nondimensional results presented in this article enable preliminary design of centrifugal pumps for VADs and MCS devices.

  15. Influence of low-specific speed pump modifications on stability of Y-Q curve

    NASA Astrophysics Data System (ADS)

    Klas, Roman; Pochylý, František; Rudolf, Pavel

    2015-05-01

    Contribution is focused on modification of low-specific speed pump impellers with respect to stability of their Y-Q curves (i.e. head curves). The design modifications are driven by analysis of the dissipated power. First, dissipated power is evaluated by CFD software in individual working parts of the pump and then its dependence on flow rate is investigated. Pressure fields within the pump are also carefully examined. Special attention is paid to impellers and configuration of the blade channels and recirculating channels. Results point to significant influence of the proper inflow to recirculating channels and also to role of the volute, which is more pronounced than in conventional impellers. All integral characteristics from CFD simulations are verified experimentally.

  16. Dissociating perception from judgment in the action-specific effect of blocking ease on perceived speed.

    PubMed

    Witt, Jessica K; Tenhundfeld, Nathan L; Bielak, Allison A M

    2017-01-01

    The action-specific approach to perception claims that a person's ability to act directly influences perceptual processes related to spatial vision. For example, a person's ability to block a moving ball impacts perceptual judgments of the ball's speed. However, an alternative explanation is that action rather than perception influences judgments. Here, we explore this distinction directly. Our method produces two distinct effects, one that is clearly a judgment-based effect and is based on the outcome of the trial (trial-outcome effect) and one that is under debate as to whether or not it is perceptual and is based on the ease with which the ball can be blocked (paddle-size effect). We explored whether these two effects would produce convergence or dissociations across various populations and manipulations. A dissociation is evidence for two separate underlying processes, whereas if the two effects did not dissociate, this would be consistent with claims that both effects were judgment-based. In Experiment 1, we examined whether older and younger adults would show a dissociation between the two effects given some precedent for older adults to show greater susceptibility to nonperceptual factors in their judgments. In Experiment 2, we used a cover story to excuse poor performance and examined its effects on both types of effects. Both experiments revealed dissociations, suggesting that while one effect is judgment-based, the other effect is not. Coupled with prior research, we conclude that the action-specific effect of ease to block a ball on estimated ball speed is perceptual.

  17. Valve for gas centrifuges

    DOEpatents

    Hahs, C.A.; Rurbage, C.H.

    1982-03-17

    The invention is pneumatically operated valve assembly for simulatenously (1) closing gas-transfer lines connected to a gas centrifuge or the like and (2) establishing a recycle path between two on the lines so closed. The value assembly is especially designed to be compact, fast-acting, reliable, and comparatively inexpensive. It provides large reductions in capital costs for gas-centrifuge cascades.

  18. A biological safety centrifuge.

    PubMed

    Hall, C V

    1975-04-01

    The Washington State Public Health Laboratories has devised a metho to capture and remove aerosols produced during centrifugation. The method to adapt any centrifuge having an enclosed chamber with an air intake hole in the lid, and an exhaust hole in the bottom of the chamber, is discussed.

  19. METHOD OF CENTRIFUGE OPERATION

    DOEpatents

    Cohen, K.

    1960-05-10

    A method of isotope separation is described in which two streams are flowed axially of, and countercurrently through, a cylindrical centrifuge bowl. Under the influence of a centrifugal field, the light fraction is concentrated in a stream flowing through the central portion of the bowl, whereas the heavy fraction is concentrated in a stream at the periphery thereof.

  20. Centrifuge: rapid and sensitive classification of metagenomic sequences.

    PubMed

    Kim, Daehwan; Song, Li; Breitwieser, Florian P; Salzberg, Steven L

    2016-12-01

    Centrifuge is a novel microbial classification engine that enables rapid, accurate, and sensitive labeling of reads and quantification of species on desktop computers. The system uses an indexing scheme based on the Burrows-Wheeler transform (BWT) and the Ferragina-Manzini (FM) index, optimized specifically for the metagenomic classification problem. Centrifuge requires a relatively small index (4.2 GB for 4078 bacterial and 200 archaeal genomes) and classifies sequences at very high speed, allowing it to process the millions of reads from a typical high-throughput DNA sequencing run within a few minutes. Together, these advances enable timely and accurate analysis of large metagenomics data sets on conventional desktop computers. Because of its space-optimized indexing schemes, Centrifuge also makes it possible to index the entire NCBI nonredundant nucleotide sequence database (a total of 109 billion bases) with an index size of 69 GB, in contrast to k-mer-based indexing schemes, which require far more extensive space. © 2016 Kim et al.; Published by Cold Spring Harbor Laboratory Press.

  1. Centrifuge: rapid and sensitive classification of metagenomic sequences

    PubMed Central

    Song, Li; Breitwieser, Florian P.

    2016-01-01

    Centrifuge is a novel microbial classification engine that enables rapid, accurate, and sensitive labeling of reads and quantification of species on desktop computers. The system uses an indexing scheme based on the Burrows-Wheeler transform (BWT) and the Ferragina-Manzini (FM) index, optimized specifically for the metagenomic classification problem. Centrifuge requires a relatively small index (4.2 GB for 4078 bacterial and 200 archaeal genomes) and classifies sequences at very high speed, allowing it to process the millions of reads from a typical high-throughput DNA sequencing run within a few minutes. Together, these advances enable timely and accurate analysis of large metagenomics data sets on conventional desktop computers. Because of its space-optimized indexing schemes, Centrifuge also makes it possible to index the entire NCBI nonredundant nucleotide sequence database (a total of 109 billion bases) with an index size of 69 GB, in contrast to k-mer-based indexing schemes, which require far more extensive space. PMID:27852649

  2. Hydraulic design of a low-specific speed Francis runner for a hydraulic cooling tower

    NASA Astrophysics Data System (ADS)

    Ruan, H.; Luo, X. Q.; Liao, W. L.; Zhao, Y. P.

    2012-11-01

    The air blower in a cooling tower is normally driven by an electromotor, and the electric energy consumed by the electromotor is tremendous. The remaining energy at the outlet of the cooling cycle is considerable. This energy can be utilized to drive a hydraulic turbine and consequently to rotate the air blower. The purpose of this project is to recycle energy, lower energy consumption and reduce pollutant discharge. Firstly, a two-order polynomial is proposed to describe the blade setting angle distribution law along the meridional streamline in the streamline equation. The runner is designed by the point-to-point integration method with a specific blade setting angle distribution. Three different ultra-low-specificspeed Francis runners with different wrap angles are obtained in this method. Secondly, based on CFD numerical simulations, the effects of blade setting angle distribution on pressure coefficient distribution and relative efficiency have been analyzed. Finally, blade angles of inlet and outlet and control coefficients of blade setting angle distribution law are optimal variables, efficiency and minimum pressure are objective functions, adopting NSGA-II algorithm, a multi-objective optimization for ultra-low-specific speed Francis runner is carried out. The obtained results show that the optimal runner has higher efficiency and better cavitation performance.

  3. Sound generation in centrifugal compressors

    NASA Astrophysics Data System (ADS)

    Raitor, Till; Neise, Wolfgang

    2008-07-01

    An experimental study is described to explore the dominant sound generation mechanisms of the spectral components governing the overall noise level of centrifugal compressors. At the design speed with supersonic flow conditions in the rotor blade channels, blade tone noise and buzz-saw noise are the main contributors. On the inlet, rotor-alone noise is the main source while rotor-stator interaction noise dominates on the outlet side in case of vaned outlet diffusers. Over a large range of rotor speeds with subsonic flow conditions, radial compressor noise is dominated by tip clearance noise which is produced by the secondary flow through the gap between rotor blade tips and the casing wall which in turn gives rise to the rotating instability phenomena observed earlier in axial-flow machines.

  4. System analysis of plasma centrifuges and sputtering

    NASA Technical Reports Server (NTRS)

    Hong, S. H.

    1978-01-01

    System analyses of cylindrical plasma centrifuges are presented, for which the velocity field and electromagnetic fields are calculated. The effects of different electrode geometrics, induced magnetic fields, Hall-effect, and secondary flows are discussed. It is shown that speeds of 10000 m/sec can be achieved in plasma centrifuges, and that an efficient separation of U238 and U235 in uranium plasmas is feasible. The external boundary-value problem for the deposition of sputtering products is reduced to a Fredholm integral equation, which is solved analytically by means of the method of successive approximations.

  5. Centrifuge workers study. Phase II, completion report

    SciTech Connect

    Wooten, H.D.

    1994-09-01

    Phase II of the Centrifuge Workers Study was a follow-up to the Phase I efforts. The Phase I results had indicated a higher risk than expected among centrifuge workers for developing bladder cancer when compared with the risk in the general population for developing this same type of cancer. However, no specific agent could be identified as the causative agent for these bladder cancers. As the Phase II Report states, Phase I had been limited to workers who had the greatest potential for exposure to substances used in the centrifuge process. Phase II was designed to expand the survey to evaluate the health of all employees who had ever worked in Centrifuge Program Departments 1330-1339 but who had not been interviewed in Phase I. Employees in analytical laboratories and maintenance departments who provided support services for the Centrifuge Program were also included in Phase II. In December 1989, the Oak Ridge Associated Universities (ORAU), now known as Oak Ridge Institute for Science and Education (ORISE), was contracted to conduct a follow-up study (Phase II). Phase H of the Centrifuge Workers Study expanded the survey to include all former centrifuge workers who were not included in Phase I. ORISE was chosen because they had performed the Phase I tasks and summarized the corresponding survey data therefrom.

  6. Centrifuge for SLS-1

    NASA Image and Video Library

    1981-01-16

    S81-25565 (Feb 1981) --- Expected to be a busy item of flight hardware on the Spacelab Life Sciences (SLS-1) mission is this low-gravity centrifuge. To be flown onboard Columbia for STS-40, the centrifuge is able to simulate several gravity levels (0.5 g, 1.0 g, 1.5 g. and 2.0 g). Blood samples, taken during the flight, will be placed in the centrifuge, fixed for post flight analysis and transferred to a freezer.

  7. Velocity and pressure measurements in guide vane clearance gap of a low specific speed Francis turbine

    NASA Astrophysics Data System (ADS)

    Thapa, B. S.; Dahlhaug, O. G.; Thapa, B.

    2016-11-01

    In Francis turbine, a small clearance gap between the guide vanes and the cover plates is usually required to pivot guide vanes as a part of governing system. Deflection of cover plates and erosion of mating surfaces causes this gap to increase from its design value. The clearance gap induces the secondary flow in the distributor system. This effects the main flow at the runner inlet, which causes losses in efficiency and instability. A guide vane cascade of a low specific speed Francis turbine has been developed for experimental investigations. The test setup is able to produce similar velocity distributions at the runner inlet as that of a reference prototype turbine. The setup is designed for particle image velocimetry (PIV) measurements from the position of stay vane outlet to the position of runner inlet. In this study, velocity and pressure measurements are conducted with 2 mm clearance gap on one side of guide vane. Leakage flow is observed and measured together with pressure measurements. It is concluded that the leakage flow behaves as a jet and mixes with the main flow in cross-wise direction and forms a vortex filament. This causes non-uniform inlet flow conditions at runner blades.

  8. Hydraulic Performance Comparison for Axial Flow Impeller and Mixed Flow Impeller with Same Specific Speed

    NASA Astrophysics Data System (ADS)

    Pan, Zhongyong; Ni, Yongyan; Yuan, Jianping; Ji, Pei

    2015-12-01

    An axial flow impeller and a mixed flow impeller with same specific speed were experimentally investigated, and the suction performance was studied with the help of CFD simulations. The results show that the axial impeller is roughly better than the mixed flow one. Especially under the design condition and a low flow rate condition range near the designed one, the axial flow impeller is more stable and therefore more suitable to be used in a water jet propulsion, while under these conditions the mixed flow impeller displays significant discrepancies. On the other hand, though its efficiency at the best efficiency point is lower than that of the axial flow one, the mixed flow impeller has a larger range of high efficiency conditions and is more convenient to be controlled to satisfy the irrigation and drainage systems that ought to be adjusted to varied flow rate conditions under a fixed head. In addition, the numerical investigation at the rated point shows that the axial impeller has a much better suction performance than the mixed flow impeller, which contradicts with the experience knowledge and therefore details need to be further studied.

  9. Evaluation of a specific reaction and action speed test for the soccer goalkeeper.

    PubMed

    Knoop, Marco; Fernandez-Fernandez, Jaime; Ferrauti, Alexander

    2013-08-01

    The aim of this study was to develop and evaluate a new test for the soccer goalkeeper that involved perceptual and movement response components (i.e., sprint running, jumping, diving, and direction changing). The evaluation consisted of measurements in different age (U19 [18.0 ± 0.9 years], n = 21; U14 [14.1 ± 0.3 years], n = 13) and performance (i.e., first goalkeepers and substitutes) groups of goalkeepers, including measures of test-retest reliability. Validity was assessed comparing the 2 groups of goalkeepers with different expertise levels (i.e., competitive level and age group). The test-retest correlations of the reaction and action speed (RAS) test performance were significant in all single (intraclass correlation coefficient [ICC] = 0.68-0.95; p < 0.01) and complex measurements (ICC = 0.91; p < 0.01). The RAS single test performance was higher in older (U19) compared with in younger (U14) players (p < 0.001), and they also showed better results in the RAS complex tests (p = 0.000), being significantly different between the first goalkeepers and their substitutes (p = 0.001). Moreover, for all age groups (i.e., U14, U19), defensive actions to the bottom corners were faster than those to the top corners, with large ES (i.e., > 1). The major findings of the study were that the RAS test provided a reliable and valid method of assessing specific defensive agility in a group of youth soccer goalkeepers. Performance responses during the RAS test allow coaches to discriminate between age-matched goalkeepers, identify weaknesses (e.g., nonpreferred side dive performance), and to design specific training tasks.

  10. Valve for gas centrifuges

    DOEpatents

    Hahs, Charles A.; Burbage, Charles H.

    1984-01-01

    The invention is a pneumatically operated valve assembly for simultaneously (1) closing gas-transfer lines connected to a gas centrifuge or the like and (2) establishing a recycle path between two of the lines so closed. The valve assembly is especially designed to be compact, fast-acting, reliable, and comparatively inexpensive. It provides large reductions in capital costs for gas-centrifuge cascades.

  11. Two-Stage Centrifugal Fan

    NASA Technical Reports Server (NTRS)

    Converse, David

    2011-01-01

    Fan designs are often constrained by envelope, rotational speed, weight, and power. Aerodynamic performance and motor electrical performance are heavily influenced by rotational speed. The fan used in this work is at a practical limit for rotational speed due to motor performance characteristics, and there is no more space available in the packaging for a larger fan. The pressure rise requirements keep growing. The way to ordinarily accommodate a higher DP is to spin faster or grow the fan rotor diameter. The invention is to put two radially oriented stages on a single disk. Flow enters the first stage from the center; energy is imparted to the flow in the first stage blades, the flow is redirected some amount opposite to the direction of rotation in the fixed stators, and more energy is imparted to the flow in the second- stage blades. Without increasing either rotational speed or disk diameter, it is believed that as much as 50 percent more DP can be achieved with this design than with an ordinary, single-stage centrifugal design. This invention is useful primarily for fans having relatively low flow rates with relatively high pressure rise requirements.

  12. MHD Stability of Centrifugally Confined Plasmas

    NASA Astrophysics Data System (ADS)

    Huang, Yi-Min

    2003-10-01

    Centrifugally confined plasmas utilize centrifugal forces from plasma rotation to augment magnetic confinement, as an alternative approach to fusion. One magnetic geometry is mirror-type, with rotation about the axis induced from a central, biased core conductor. The outward centrifugal forces from the rotation have a component along the field lines, thus confining ions to the center. The immediate concern, of course, is that the system could be flute unstable to the interchange. The antidote here is that the radial shear in the rotation could stabilize the flute. Our 2D simulations show, first, that plasma pressure is highly peaked at the center away from the mirror end coils. Next, 3D simulations show unequivocally that velocity shear is providing the stability. Further study indicates that the flute stability is sensitive to the density profile. A favorable density profile could be achieved by judiciously placing the particle source, also necessary for a steady state centrifuge. As flows approach the Alfven speed, electromagnetic modes could be involved. The latter is motivated by the question of whether magnetorotational instability, thought to be an angular momentum transporter in accretion disks, could be found in centrifugal plasmas, since all the ingredients are there. We show that the MRI as understood should be stable; however, a related astrophysical instability, the Parker instability, could arise. The Parker instability results in plasma accumulating in regions of bent field lines, further accentuating the bending.

  13. ORNL centrifuge pellet fueling system

    SciTech Connect

    Foster, C.A.; Houlberg, W.A.; Gouge, M.J.; Grapperhaus, M.J.; Milora, S.L. ); Drawin, H.; Geraud, A.; Chatelier, M.; Gros, G. )

    1992-01-01

    A centrifuge pellet injecter designed and built at Oak Ridge National Laboratory (ORNL) is in operation on Tore Supra. This injector has the capability of injecting up to 100 pellets at speeds up to 800 M/s. The solid deuterium pellets can be formed with a variable mass from 3 to 10 torr-L and are fired at a rate of up to 10 pellets per second. The experimental program that is under way combines repetitive pellet fueling with the ergodic divertor and pump limiters to establish and understand long-pulse plasmas in which the pellet fuel source is in balance with the particle exhaust. With lower hybrid current drive, pulse lengths of up to 2 min might be achieved. To prepare for these extended pulse lengths, the pellet source on the centrifuge will be extended to provide a 300- to 500-pellet capability. A similar system extended to steady-state pellet fabrication technology and designed for a radiation and tritium environment would be a candidate for a fueling system for the International Thermonuclear Experimental Reactor (ITER). Analysis of pellet-fueled ITER discharges using the WHIST code shows the potential for controlling the radial fuel deposition point to achieve the desired core density while maintaining the edge density and temperatures so as to minimize the diverter plate erosion. A centrifuge fueling system would have the capability of taking the D-T exhaust directly from the cryopumping systems, recondensing and purifying the fuel, and injecting the reconstituted pellets into the plasma, thereby minimizing the tritium inventory.

  14. ORNL centrifuge pellet fueling system

    SciTech Connect

    Foster, C.A.; Houlberg, W.A.; Gouge, M.J.; Grapperhaus, M.J.; Milora, S.L.; Drawin, H.; Geraud, A.; Chatelier, M.; Gros, G.

    1992-11-01

    A centrifuge pellet injecter designed and built at Oak Ridge National Laboratory (ORNL) is in operation on Tore Supra. This injector has the capability of injecting up to 100 pellets at speeds up to 800 M/s. The solid deuterium pellets can be formed with a variable mass from 3 to 10 torr-L and are fired at a rate of up to 10 pellets per second. The experimental program that is under way combines repetitive pellet fueling with the ergodic divertor and pump limiters to establish and understand long-pulse plasmas in which the pellet fuel source is in balance with the particle exhaust. With lower hybrid current drive, pulse lengths of up to 2 min might be achieved. To prepare for these extended pulse lengths, the pellet source on the centrifuge will be extended to provide a 300- to 500-pellet capability. A similar system extended to steady-state pellet fabrication technology and designed for a radiation and tritium environment would be a candidate for a fueling system for the International Thermonuclear Experimental Reactor (ITER). Analysis of pellet-fueled ITER discharges using the WHIST code shows the potential for controlling the radial fuel deposition point to achieve the desired core density while maintaining the edge density and temperatures so as to minimize the diverter plate erosion. A centrifuge fueling system would have the capability of taking the D-T exhaust directly from the cryopumping systems, recondensing and purifying the fuel, and injecting the reconstituted pellets into the plasma, thereby minimizing the tritium inventory.

  15. A Methodological Report: Adapting the 505 Change-of-Direction Speed Test Specific to American Football.

    PubMed

    Lockie, Robert G; Farzad, Jalilvand; Orjalo, Ashley J; Giuliano, Dominic V; Moreno, Matthew R; Wright, Glenn A

    2017-02-01

    Lockie, RG, Jalilvand, F, Orjalo, AJ, Giuliano, DV, Moreno, MR, and Wright, GA. A methodological report: Adapting the 505 change-of-direction speed test specific to American football. J Strength Cond Res 31(2): 539-547, 2017-The 505 involves a 10-m sprint past a timing gate, followed by a 180° change-of-direction (COD) performed over 5 m. This methodological report investigated an adapted 505 (A505) designed to be football-specific by changing the distances to 10 and 5 yd. Twenty-five high school football players (6 linemen [LM]; 8 quarterbacks, running backs, and linebackers [QB/RB/LB]; 11 receivers and defensive backs [R/DB]) completed the A505 and 40-yd sprint. The difference between A505 and 0 to 10-yd time determined the COD deficit for each leg. In a follow-up session, 10 subjects completed the A505 again and 10 subjects completed the 505. Reliability was analyzed by t-tests to determine between-session differences, typical error (TE), and coefficient of variation. Test usefulness was examined via TE and smallest worthwhile change (SWC) differences. Pearson's correlations calculated relationships between the A505 and 505, and A505 and COD deficit with the 40-yd sprint. A 1-way analysis of variance (p ≤ 0.05) derived between-position differences in the A505 and COD deficit. There were no between-session differences for the A505 (p = 0.45-0.76; intraclass correlation coefficient = 0.84-0.95; TE = 2.03-4.13%). Additionally, the A505 was capable of detecting moderate performance changes (SWC0.5 > TE). The A505 correlated with the 505 and 40-yard sprint (r = 0.58-0.92), suggesting the modified version assessed similar qualities. Receivers and defensive backs were faster than LM in the A505 for both legs, and right-leg COD deficit. Quarterbacks, running backs, and linebackers were faster than LM in the right-leg A505. The A505 is reliable, can detect moderate performance changes, and can discriminate between football position groups.

  16. Naming Speed as a Clinical Marker in Predicting Basic Calculation Skills in Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Kleemans, Tijs; Segers, Eliane; Verhoeven, Ludo

    2012-01-01

    The present study investigated the role of naming speed in predicting the basic calculation skills (i.e., addition and subtraction) of kindergartners with Specific Language Impairment (SLI), when compared to a group of Normal Language Achieving (NLA) children. Fifty-three kindergartners with SLI and 107 kindergartners with NLA were tested on…

  17. Naming Speed as a Clinical Marker in Predicting Basic Calculation Skills in Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Kleemans, Tijs; Segers, Eliane; Verhoeven, Ludo

    2012-01-01

    The present study investigated the role of naming speed in predicting the basic calculation skills (i.e., addition and subtraction) of kindergartners with Specific Language Impairment (SLI), when compared to a group of Normal Language Achieving (NLA) children. Fifty-three kindergartners with SLI and 107 kindergartners with NLA were tested on…

  18. Small centrifugal pumps for low-thrust rocket engines

    NASA Technical Reports Server (NTRS)

    Furst, R. B.

    1986-01-01

    Six small, low specific speed centrifugal pump configurations were designed, fabricated, and tested. The configurations included shrouded, and 25 and 100% admission open face impellers with 2 inch tip diameters; 25, 50, and 100% emission vaned diffusers; and volutes with conical exits. Impeller tip widths varied from 0.030 inch to 0.052 inch. Design specific speeds (N sub s = RPM*GPM**0.5.FT**0.75) were 430 (four configurations) and 215 (two configurations). The six configurations were tested with water as the pumped fluid. Noncavitating performance results are presented for the design speed of 24,500 rpm over a flowrate range from 1 to 6 gpm for the N sub s = 430 configurations and test speeds up to 29,000 rpm over a flowrate range from 0.3 to 1.2 gpm for the N sub s = 215 configurations. Cavitating performance results are presented over a flowrate range from 60 to 120% of design flow. Fabrication of the small pump conponents is also discussed.

  19. Centrifugal main fuel pump

    SciTech Connect

    Cole, E.F.

    1986-08-26

    For a gas turbine power plant having a fuel supply and a fuel metering valve and variable geometry for the power plant including servo actuating mechanisms for the fuel metering valve and variable geometry, a fuel pumping system, is described to supply pressurized fuel for the servo actuating mechanisms and for the engine working fluid medium. The pumping system includes a centrifugal pump solely supplying the fuel to the fuel metering valve to be delivered to the power plant for its working fluid medium, a positive displacement pump in parallel with the centrifugal pump and solely to supply pressurized fuel to the servo actuating mechanisms for the fuel metering valve and for the variable geometry, and a boost pump means disposed in serial relationship with the positive displacement pump and the centrifugal pump for augmenting the pressure supplied by the positive displacement pump and the centrifugal pump during predetermined operating conditions of the power plant. The combined boost pump and centrifugal pump capability is sufficient to satisfy the vapor to liquid ratio requirements of the power during its entire operating envelope.

  20. Operating and maintenance guidelines for screenbowl centrifuges

    SciTech Connect

    Jahnig, W.S.R.; Bratton, R.; Luttrell, G.

    2009-01-15

    Plant dewatering circuits equipped with screenbowl centrifuges need to be well designed, properly operated, and adequately maintained to maximize the dewatering performance. The most important 'feed variables' are particle size, dry solids feed rate and slurry flow rate. The most important 'machine variables' include pool depth, rotational speed and gearbox ratio. The article discusses the effect of these parameters and offers some maintenance guidelines. The article was adapted from a paper presented at CoalPrep 2008. 6 refs., 2 figs., 2 tabs.

  1. Naming speed as a clinical marker in predicting basic calculation skills in children with specific language impairment.

    PubMed

    Kleemans, Tijs; Segers, Eliane; Verhoeven, Ludo

    2012-01-01

    The present study investigated the role of naming speed in predicting the basic calculation skills (i.e., addition and subtraction) of kindergartners with Specific Language Impairment (SLI), when compared to a group of Normal Language Achieving (NLA) children. Fifty-three kindergartners with SLI and 107 kindergartners with NLA were tested on cognitive, linguistic and basic calculation skills. The results showed that phonological awareness, grammatical ability, general intelligence and working memory accounted for the variation in the basic calculation skills of both groups. However, an additional effect of naming speed on both addition and subtraction was found for the group of children with SLI, suggesting that naming speed may act as a clinical marker in identifying those children who are likely to develop problems in basic calculation skills.

  2. An Application-Specific Compiler for High-Speed Binary Image Morphology

    DTIC Science & Technology

    2006-01-01

    unclassified b. ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 pilation speed. We will...large disadvantage: the .ngd file is a pro- prietary Xilinx file, and we have no guarantee that the for- mat will not be changed in the future. If this

  3. Cognitive Risk Factors for Specific Learning Disorder: Processing Speed, Temporal Processing, and Working Memory.

    PubMed

    Moll, Kristina; Göbel, Silke M; Gooch, Debbie; Landerl, Karin; Snowling, Margaret J

    2016-01-01

    High comorbidity rates between reading disorder (RD) and mathematics disorder (MD) indicate that, although the cognitive core deficits underlying these disorders are distinct, additional domain-general risk factors might be shared between the disorders. Three domain-general cognitive abilities were investigated in children with RD and MD: processing speed, temporal processing, and working memory. Since attention problems frequently co-occur with learning disorders, the study examined whether these three factors, which are known to be associated with attention problems, account for the comorbidity between these disorders. The sample comprised 99 primary school children in four groups: children with RD, children with MD, children with both disorders (RD+MD), and typically developing children (TD controls). Measures of processing speed, temporal processing, and memory were analyzed in a series of ANCOVAs including attention ratings as covariate. All three risk factors were associated with poor attention. After controlling for attention, associations with RD and MD differed: Although deficits in verbal memory were associated with both RD and MD, reduced processing speed was related to RD, but not MD; and the association with RD was restricted to processing speed for familiar nameable symbols. In contrast, impairments in temporal processing and visuospatial memory were associated with MD, but not RD. © Hammill Institute on Disabilities 2014.

  4. Geotechnical centrifuge under construction

    NASA Astrophysics Data System (ADS)

    Richman, Barbara T.

    Modifications are underway at the National Aeronautics and Space Administration (NASA) Ames Research Center in California to transform a centrifuge used in the Apollo space program to the largest geotechnical centrifuge in the free world. The centrifuge, to be finished in August and opened next January, following check out and tuning, will enable geoscientists to model stratigraphic features down to 275 m below the earth's surface. Scientists will be able to model processes that are coupled with body force loading, including earthquake response of earth structures and soil structure interaction; rubbled-bed behavior during in situ coal gasification or in oil shale in situ retorts; behavior of frozen soil; frost heave; behavior of offshore structures; wave-seabed interactions; explosive cratering; and blast-induced liquefaction.The centrifuge will have a load capacity of 900-g-tons (short); that is, it will be able to carry a net soil load of 3 short tons to a centripetal acceleration of 300 times the acceleration caused by gravity. Modified for a total cost of $2.4 million, the centrifuge will have an arm with a 7.6-m radius and a swinging platform or bucket at its end that will be able to carry a payload container measuring 2.1×2.1 m. An additional future input of $500,000 would enable the purchase of a larger bucket that could accommodate a load of up to 20 tons, according to Charles Babendreier, program director for geotechnical engineering at the National Science Foundation. Additional cooling for the motor would also be required. The centrifuge has the capability of accelerating the 20-ton load to 100 g.

  5. Tropic Responses of Phycomyces Sporangiophores to Gravitational and Centrifugal Stimuli

    PubMed Central

    Dennison, David S.

    1961-01-01

    A low-speed centrifuge was used to study the tropic responses of Phycomyces sporangiophores in darkness to the stimulus of combined gravitational and centrifugal forces. If this stimulus is constant the response is a relatively slow tropic reaction, which persists for up to 12 hours. The response is accelerated by increasing the magnitude of the gravitational-centrifugal force. A wholly different tropic response, the transient response, is elicited by an abrupt change in the gravitational-centrifugal stimulus. The transient response has a duration of only about 6 min. but is characterized by a high bending speed (about 5°/min.). An analysis of the distribution of the transient response along the growing zone shows that the active phase of the response has a distribution similar to that of the light sensitivity for the light-growth and phototropic responses. Experiments in which sporangiophores are centrifuged in an inert dense fluid indicate that the sensory mechanism of the transient response is closely related to the physical deformation of the growing zone caused by the action of the gravitational-centrifugal force on the sporangiophore as a whole. However, the response to a steady gravitational-centrifugal force is most likely not connected with this deformation, but is probably triggered by the shifting of regions or particles of differing density relative to one another inside the cell. PMID:13721903

  6. Centrifugal projectile launchers

    NASA Astrophysics Data System (ADS)

    Felber, F. S.

    1982-01-01

    The concept of a centrifugal projectile launcher as an alternative to both chemical and electromagnetic launchers for anti-tank and air defence systems is discussed. It is shown that centrifugal projectile launchers can provide reliable, efficient, compact systems that will accelerate projectiles to 2-3 km/s with energies up to one megajoule. State-of-the-art composite rotors can be modified to launch projectiles of tens of grams to the order of 1 km/s. A demonstration rotor with reasonable energy density can be designed to accelerate 60 gram projectiles to 3 km/s repetitively.

  7. Lightweight Shield for Centrifuge

    NASA Technical Reports Server (NTRS)

    Luper, C.

    1982-01-01

    Centrifuge bowl composed of laminated aluminum offers required combination of high strength at reduced weight. Around outside wall of bowl core of 1/16 inch thick spun aluminum are wrapped two layers of aluminum, each also one-sixteenth inch thick. Layered structure prevents cracks from propagating through wall.

  8. Centrifuge pump selection

    SciTech Connect

    Buehler, M.W.

    1985-12-01

    Selection of a centrifuge pump is addressed. The problem of assessing pump needs based on system design is broken down into a step-by-step approach. Topics included are designing the pump system, calculating such pressure NPSH, and building in a safety factor.

  9. Human Powered Centrifuge

    NASA Technical Reports Server (NTRS)

    Mulenburg, Gerald M. (Inventor); Vernikos, Joan (Inventor)

    1997-01-01

    A human powered centrifuge has independently established turntable angular velocity and human power input. A control system allows excess input power to be stored as electric energy in a battery or dissipated as heat through a resistors. In a mechanical embodiment, the excess power is dissipated in a friction brake.

  10. Centrifugal Gas Compression Cycle

    NASA Astrophysics Data System (ADS)

    Fultun, Roy

    2002-11-01

    A centrifuged gas of kinetic, elastic hard spheres compresses isothermally and without flow of heat in a process that reverses free expansion. This theorem follows from stated assumptions via a collection of thought experiments, theorems and other supporting results, and it excludes application of the reversible mechanical adiabatic power law in this context. The existence of an isothermal adiabatic centrifugal compression process makes a three-process cycle possible using a fixed sample of the working gas. The three processes are: adiabatic mechanical expansion and cooling against a piston, isothermal adiabatic centrifugal compression back to the original volume, and isochoric temperature rise back to the original temperature due to an influx of heat. This cycle forms the basis for a Thomson perpetuum mobile that induces a loop of energy flow in an isolated system consisting of a heat bath connectable by a thermal path to the working gas, a mechanical extractor of the gas's internal energy, and a device that uses that mechanical energy and dissipates it as heat back into the heat bath. We present a simple experimental procedure to test the assertion that adiabatic centrifugal compression is isothermal. An energy budget for the cycle provides a criterion for breakeven in the conversion of heat to mechanical energy.

  11. Enhancing Centrifugal Separation With Electrophoresis

    NASA Technical Reports Server (NTRS)

    Herrmann, F. T.

    1986-01-01

    Separation of biological cells by coil-planet centrifuge enhanced by electrophoresis. By itself, coil-planet centrifuge offers relatively gentle method of separating cells under low centrifugal force in physiological medium that keeps cells alive. With addition of voltage gradient to separation column of centrifuge, separation still gentle but faster and more complete. Since separation apparatus contains no rotary seal, probability of leakage, contamination, corrosion, and short circuits reduced.

  12. The Human Centrifuge

    NASA Astrophysics Data System (ADS)

    van Loon, Jack J. W. A.

    2009-01-01

    Life on Earth has developed at unit gravity, 9.81 m/s2, which was a major factor especially when vertebrates emerged from water onto land in the late Devonian, some 375 million years ago. But how would nature have evolved on a larger planet? We are able to address this question simply in experiments using centrifuges. Based on these studies we have gained valuable insights in the physiological process in plants and animals. They adapt to a new steady state suitable for the high-g environments applied. Information on mammalian adaptations to hyper-g is interesting or may be even vital for human space exploration programs. It has been shown in long duration animal hypergravity studies, ranging from snails, rats to primates, that various structures like muscles, bones, neuro-vestibular, or the cardio-vascular system are affected. However, humans have never been exposed to a hyper-g environment for long durations. Centrifuge studies involving humans are mostly in the order of hours. The current work on human centrifuges are all focused on short arm systems to apply short periods of artificial gravity in support of long duration space missions in ISS or to Mars. In this paper we will address the possible usefulness of a large human centrifuge on Earth. In such a centrifuge a group of humans can be exposed to hypergravity for, in principle, an unlimited period of time like living on a larger planet. The input from a survey under scientists working in the field of gravitational physiology, but also other disciplines, will be discussed.

  13. Solvent-free cleaning using a centrifugal cryogenic pellet accelerator

    SciTech Connect

    Haines, J.R.; Fisher, P.W.; Foster, C.A.

    1995-06-01

    An advanced centrifuge that accelerates frozen CO{sub 2} pellets to high speeds for surface cleaning and paint removal is being developed at the Oak Ridge National Laboratory. The centrifuge-based accelerator was designed, fabricated, and tested under a program sponsored by the Warner Robins Air Logistics Center, Robins Air Force Base, Georgia. In comparison to the more conventional compressed air ``sandblast`` pellet accelerators, the centrifugal accelerator system can achieve higher pellet speeds, has precise speed control, and is more than ten times as energy efficient. Furthermore, the use of frozen CO{sub 2} pellets instead of conventional metal, plastic, sand, or other abrasive materials that remain solid at room temperature, minimizes the waste stream. This apparatus has been used to demonstrate cleaning of various surfaces, including removal of paint, oxide coatings, metal coatings, organic coatings, and oil and grease coatings from a variety of surfaces. The design and operation of the apparatus is discussed.

  14. Effect of relative centrifugal force and centrifugation time on sedimentation of mycobacteria in clinical specimens.

    PubMed

    Ratnam, S; March, S B

    1986-03-01

    Optimum relative centrifugal force (RCF) and centrifugation time to concentrate mycobacteria in clinical specimens were determined by processing split samples of sputa and urines containing mycobacteria with combinations of different RCFs and centrifugation times. Although individual test results showed considerable variation in the recovery rates of mycobacteria in the sediment, the data indicated that higher recovery rates occurred as centrifugation speed and time were increased. With a 15- to 20-min centrifugation time, on the average, 67 to 71% of mycobacteria were recovered at an RCF of 2,074 X g, and 76 to 80% were recovered at 3,005 or 3,895 X g at maximum radius. The remainder of mycobacteria was mostly recovered from the supernatant, but culturing of supernatant was not profitable. Increasing RCF had a negligible effect on acid-fast bacillus smear sensitivity. The smear sensitivity for about 25,000 clinical specimens processed with an RCF of 3,800 X g for 20 min was 71% compared with 69% as determined for over 30,000 specimens processed in a similar manner but an RCF of 2,000 X g. An RCF of 3,000 X g applied for 15 min, or an RCF of about 2,000 to 2,500 X g applied for 20 min, is considered adequate to concentrate mycobacteria in clinical specimens.

  15. Effect of relative centrifugal force and centrifugation time on sedimentation of mycobacteria in clinical specimens.

    PubMed Central

    Ratnam, S; March, S B

    1986-01-01

    Optimum relative centrifugal force (RCF) and centrifugation time to concentrate mycobacteria in clinical specimens were determined by processing split samples of sputa and urines containing mycobacteria with combinations of different RCFs and centrifugation times. Although individual test results showed considerable variation in the recovery rates of mycobacteria in the sediment, the data indicated that higher recovery rates occurred as centrifugation speed and time were increased. With a 15- to 20-min centrifugation time, on the average, 67 to 71% of mycobacteria were recovered at an RCF of 2,074 X g, and 76 to 80% were recovered at 3,005 or 3,895 X g at maximum radius. The remainder of mycobacteria was mostly recovered from the supernatant, but culturing of supernatant was not profitable. Increasing RCF had a negligible effect on acid-fast bacillus smear sensitivity. The smear sensitivity for about 25,000 clinical specimens processed with an RCF of 3,800 X g for 20 min was 71% compared with 69% as determined for over 30,000 specimens processed in a similar manner but an RCF of 2,000 X g. An RCF of 3,000 X g applied for 15 min, or an RCF of about 2,000 to 2,500 X g applied for 20 min, is considered adequate to concentrate mycobacteria in clinical specimens. PMID:3082926

  16. Numerical and Experimental Investigation of Cavitating Characteristics in Centrifugal Pump with Gap Impeller

    NASA Astrophysics Data System (ADS)

    Zhu, Bing; Chen, Hongxun; Wei, Qun

    2014-06-01

    This paper is to study the cavitating characteristics in a low specific speed centrifugal pump with gap structure impeller experimentally and numerically. A scalable DES numerical method is proposed and developed by introducing the von Karman scale instead of the local grid scale, which can switch at the RANS and LES region interface smoothly and reasonably. The SDES method can detect and grasp unsteady scale flow structures, which were proved by the flow around a triangular prism and the cavitation flow in a centrifugal pump. Through numerical and experimental research, it's shown that the simulated results match qualitatively with tested cavitation performances and visualization patterns, and we can conclude that the gap structure impeller has a superior feature of cavitation suppression. Its mechanism may be the guiding flow feature of the small vice blade and the pressure auto-balance effect of the gap tunnel.

  17. A review of leakage flow in centrifugal blood pumps.

    PubMed

    Chan, Weng-Kong; Wong, Yew-Wah

    2006-05-01

    This article presents a new approach in determining the functional relationship between the leakage flow in a centrifugal blood pump and various parameters that affect it. While high leakage flow in a blood pump is essential for good washout and can help prevent thrombus formation, excessive leakage flow will result in higher fluid shear stress that may lead to hemolysis. Dimensional analysis is employed to provide a functional relationship between leakage flow rate and other important parameters governing the operation of a centrifugal blood pump. Results showed that pump performance with a smaller gap clearance is clearly superior compared to those of two other similar pumps with larger gap clearances. It was also observed that the nondimensional leakage flow rate varies almost linearly with dimensionless pump head. It also decreases with increasing volume flow rate. A smaller gap clearance will also increase the flow resistance and hence, decrease the nondimensional leakage flow rate. Increasing surface roughness, length of the gap clearance passage, or loss coefficient of the gap geometry will increase losses and hence, decrease the leakage flow rate. It is also interesting to note that for a given pump and gap clearance geometry, the nondimensional leakage flow rate is almost independent of the Reynolds number when specific speed is constant.

  18. A preliminary investigation of the effect of hypomanic personality on the specificity and speed of autobiographical memory recall

    PubMed Central

    Delduca, Claire M.; Jones, Steven H.; Barnard, Philip

    2009-01-01

    There is some evidence that patients with bipolar disorder recall more overgeneral than specific autobiographical memories, a pattern widely reported in depression. However, there are also theoretical arguments (Barnard, Watkins, & Ramponi, 2006) suggesting that experiential processing should predominate during mania/hypomania, with an associated prediction of an increase in specific rather than overgeneral memories. This hypothesis was explicitly tested using the Autobiographical Memory Test (AMT). The specificity and speed of autobiographical recollection was compared for those with high or low levels of hypomanic personality as indexed by the Hypomanic Personality Scale (HPS). High HPS scorers recalled specific autobiographical memories in response to unpleasant cues more frequently and faster than low scorers. These results provide partial support for the hypothesis, but only for unpleasant cues. PMID:19927258

  19. Centrifugal inertia effects in two-phase face seal films

    NASA Technical Reports Server (NTRS)

    Basu, P.; Hughes, W. F.; Beeler, R. M.

    1987-01-01

    A simplified, semianalytical model has been developed to analyze the effect of centrifugal inertia in two-phase face seals. The model is based on the assumption of isothermal flow through the seal, but at an elevated temperature, and takes into account heat transfer and boiling. Using this model, seal performance curves are obtained with water as the working fluid. It is shown that the centrifugal inertia of the fluid reduces the load-carrying capacity dramatically at high speeds and that operational instability exists under certain conditions. While an all-liquid seal may be starved at speeds higher than a 'critical' value, leakage always occurs under boiling conditions.

  20. Centrifugal inertia effects in two-phase face seal films

    NASA Technical Reports Server (NTRS)

    Basu, P.; Hughes, W. F.; Beeler, R. M.

    1987-01-01

    A simplified, semianalytical model has been developed to analyze the effect of centrifugal inertia in two-phase face seals. The model is based on the assumption of isothermal flow through the seal, but at an elevated temperature, and takes into account heat transfer and boiling. Using this model, seal performance curves are obtained with water as the working fluid. It is shown that the centrifugal inertia of the fluid reduces the load-carrying capacity dramatically at high speeds and that operational instability exists under certain conditions. While an all-liquid seal may be starved at speeds higher than a 'critical' value, leakage always occurs under boiling conditions.

  1. Centrifugal unbalance detection system

    DOEpatents

    Cordaro, Joseph V.; Reeves, George; Mets, Michael

    2002-01-01

    A system consisting of an accelerometer sensor attached to a centrifuge enclosure for sensing vibrations and outputting a signal in the form of a sine wave with an amplitude and frequency that is passed through a pre-amp to convert it to a voltage signal, a low pass filter for removing extraneous noise, an A/D converter and a processor and algorithm for operating on the signal, whereby the algorithm interprets the amplitude and frequency associated with the signal and once an amplitude threshold has been exceeded the algorithm begins to count cycles during a predetermined time period and if a given number of complete cycles exceeds the frequency threshold during the predetermined time period, the system shuts down the centrifuge.

  2. Individual differences in task-specific paired associates learning in older adults: the role of processing speed and working memory.

    PubMed

    Kurtz, Tanja; Mogle, Jacqueline; Sliwinski, Martin J; Hofer, Scott M

    2013-01-01

    BACKGROUND/STUDY CONTEXT: The role of processing speed and working memory was investigated in terms of individual differences in task-specific paired associates learning in a sample of older adults. Task-specific learning, as distinct from content-oriented item-specific learning, refers to gains in performance due to repeated practice on a learning task in which the to-be-learned material changes over trials. Learning trajectories were modeled within an intensive repeated-measures design based on participants obtained from an opt-in Internet-based sampling service (M(age) = 65.3, SD = 4.81). Participants completed an eight-item paired associates task daily over a 7-day period. Results indicated that a three-parameter hyperbolic model (i.e., initial level, learning rate, and asymptotic performance) best described learning trajectory. After controlling for age-related effects, both higher working memory and higher processing speed had a positive effect on all three learning parameters. These results emphasize the role of cognitive abilities for individual differences in task-specific learning of older adults.

  3. INDIVIDUAL DIFFERENCES IN TASK-SPECIFIC PAIRED ASSOCIATES LEARNING IN OLDER ADULTS: THE ROLE OF PROCESSING SPEED AND WORKING MEMORY

    PubMed Central

    Kurtz, Tanja; Mogle, Jacqueline; Sliwinski, Martin J.; Hofer, Scott M.

    2013-01-01

    Background The role of processing speed and working memory was investigated in terms of individual differences in task-specific paired associates learning in a sample of older adults. Task-specific learning, as distinct from content-oriented item-specific learning, refers to gains in performance due to repeated practice on a learning task in which the to-be-learned material changes over trials. Methods Learning trajectories were modeled within an intensive repeated-measures design based on participants obtained from an opt-in internet-based sampling service (Mage = 65.3, SD = 4.81). Participants completed an eight-item paired associates task daily over a seven-day period. Results Results indicated that a three-parameter hyperbolic model (i.e., initial level, learning rate, and asymptotic performance) best described learning trajectory. After controlling for age-related effects, both higher working memory and higher processing speed had a positive effect on all three learning parameters. Conclusion These results emphasize the role of cognitive abilities for individual differences in task-specific learning of older adults. PMID:24151913

  4. Centrifugal Contactor Efficiency Measurements

    SciTech Connect

    Mincher, Bruce Jay; Tillotson, Richard Dean; Grimes, Travis Shane

    2017-01-01

    The contactor efficiency of a 2-cm acrylic centrifugal contactor, fabricated by ANL using 3D printer technology was measured by comparing a contactor test run to 5-min batch contacts. The aqueous phase was ~ 3 ppm depleted uranium in 3 M HNO3, and the organic phase was 1 M DAAP/dodecane. Sampling during the contactor run showed that equilibrium was achieved within < 3 minutes. The contactor efficiency at equilibrium was 95% to 100 %, depending on flowrate.

  5. Pumps, Centrifugal and Reciprocating

    DTIC Science & Technology

    2011-04-27

    reciprocating pumps. 15. SUBJECT TERMS Centrifugal pump Total discharge head Reciprocating pump Total suction head Head 16. SECURITY ... CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR 18. NUMBER OF PAGES 40 19a. NAME OF RESPONSIBLE PERSON a. REPORT B...Satisfy the needs of MIL-STD-4612. High-Altitude Electromagnetic Pulse ( HEMP ) Test Facility Satisfy the needs of MIL-STD-461. Rail Impact Test

  6. Centrifugal adsorption system

    NASA Technical Reports Server (NTRS)

    Gonda, Steve R. (Inventor); Tsao, Yow-Min D. (Inventor); Lee, Wenshan (Inventor)

    2006-01-01

    A gas-liquid separator uses a helical passageway to impart a spiral motion to a fluid passing therethrough. The centrifugal force generated by the spiraling motion urges the liquid component of the fluid radially outward which forces the gas component radially inward. The gas component is then separated through a gas-permeable, liquid-impervious membrane and discharged through a central passageway. A filter material captures target substances contained in the fluid.

  7. Centrifuge separation effect on bacterial indicator reduction in dairy manure.

    PubMed

    Liu, Zong; Carroll, Zachary S; Long, Sharon C; Roa-Espinosa, Aicardo; Runge, Troy

    2017-04-15

    Centrifugation is a commonly applied separation method for manure processing on large farms to separate solids and nutrients. Pathogen reduction is also an important consideration for managing manure. Appropriate treatment reduces risks from pathogen exposure when manure is used as soil amendments or the processed liquid stream is recycled to flush the barn. This study investigated the effects of centrifugation and polymer addition on bacterial indicator removal from the liquid fraction of manure slurries. Farm samples were taken from a manure centrifuge processing system. There were negligible changes of quantified pathogen indicator concentrations in the low-solids centrate compared to the influent slurry. To study if possible improvements could be made to the system, lab scale experiments were performed investigating a range of g-forces and flocculating polymer addition. The results demonstrated that polymer addition had a negligible effect on the indicator bacteria levels when centrifuged at high g forces. However, the higher g force centrifugation was capable of reducing bacterial indicator levels up to two-log10 in the liquid stream of the manure, although at speeds higher than typical centrifuge operations currently used for manure processing applications. This study suggests manure centrifuge equipment could be redesigned to provide pathogen reduction to meet emerging issues, such as zoonotic pathogen control. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  8. Gravitropism in Phycomyces: threshold determination on a clinostat centrifuge.

    PubMed

    Galland, Paul; Finger, Heike; Wallacher, Yvonne

    2004-06-01

    The absolute sensitivity of sporangiophores of Phycomyces blakesleeanus to centrifugal acceleration was determined on a clinostat centrifuge. The centrifuge provides centrifugal accelerations ranging from 10(-4) to 6 x g. The rotor of the centrifuge, which accommodates 96 culture vials with single sporangiophores, is clinostatted, that is, turning "head over", at slow speed (1 rev min(-1)) while it is running. The negative gravitropism of sporangiophores is characterized by two components: a polar angle, which is measured in the plane of bending, and an aiming-error angle, which indicates the deviation of the plane of bending from the vector of the centrifugal acceleration. Dose-response curves were generated for both angles with centrifugations lasting 3, 5, and 8 h. The threshold for the polar angle depends on the presence of statoliths, so-called octahedral protein crystals in the vacuoles. The albino strain C171 carAcarR (with crystals) has a threshold near 10(-2) x g while the albino strain C2 carAgeo-3 (without crystals) has a threshold of about 2 x 10(-1) x g. The threshold for the aiming error angle is ill defined and is between 10(-2) and 10(-1) x g. The threshold for the polar angle of the wild type NRRL 1555 (with crystals) is near 8 x 10(-2) x g.

  9. Reproductive-tactic-specific variation in sperm swimming speeds in a shell-brooding cichlid.

    PubMed

    Fitzpatrick, J L; Desjardins, J K; Milligan, N; Montgomerie, R; Balshine, S

    2007-08-01

    Theory predicts that males experiencing elevated levels of sperm competition will invest more in gonads and produce faster-swimming sperm. Although there is ample evidence in support of the first prediction, few studies have examined sperm swimming speed in relation to sperm competition. In this study, we tested these predictions from sperm competition theory by examining sperm characteristics in Telmatochromis vittatus, a small shell-brooding cichlid fish endemic to Lake Tanganyika. Males exhibit four different reproductive tactics: pirate, territorial, satellite, and sneaker. Pirate males temporarily displace all other competing males from a shell nest, whereas sneaker males always release sperm in the presence of territorial and satellite males. Due to the fact that sneakers spawn in the presence of another male, sneakers face the highest levels of sperm competition and pirates the lowest, whereas satellites and territorials experience intermediate levels. In accordance with predictions, sperm from sneakers swam faster than sperm from males adopting the other reproductive tactics, whereas sperm from pirates was slowest. Interestingly, we were unable to detect any variation in sperm tail length among these reproductive tactics. Thus, sperm competition appears to have influenced sperm energetics in this species without having any influence on sperm size.

  10. Balancing specificity, sensitivity, and speed of ligand discrimination by zero-order ultraspecificity

    NASA Astrophysics Data System (ADS)

    Kajita, Masashi K.; Aihara, Kazuyuki; Kobayashi, Tetsuya J.

    2017-07-01

    Specific interactions between receptors and their target ligands in the presence of nontarget ligands are crucial for biological processes such as T cell ligand discrimination. To discriminate between the target and nontarget ligands, cells have to increase specificity to the target ligands by amplifying the small differences in affinity among ligands. In addition, sensitivity to the ligand concentration and quick discrimination are also important to detect low amounts of target ligands and facilitate fast cellular decision making after ligand recognition. In this work we propose a mechanism for nonlinear specificity amplification (ultraspecificity) based on zero-order saturating reactions, which was originally proposed to explain nonlinear sensitivity amplification (ultrasensitivity) to the ligand concentration. In contrast to the previously proposed proofreading mechanisms that amplify the specificity by a multistep reaction, our model can produce an optimal balance of specificity, sensitivity, and quick discrimination. Furthermore, we show that a model for insensitivity to a large number of nontarget ligands can be naturally derived from a model with the zero-order ultraspecificity. The zero-order ultraspecificity, therefore, may provide an alternative way to understand ligand discrimination from the viewpoint of nonlinear properties in biochemical reactions.

  11. Gas Centrifuges and Nuclear Proliferation

    SciTech Connect

    Albright, David

    2004-09-15

    Gas centrifuges have been an ideal enrichment method for a wide variety of countries. Many countries have built gas centrifuges to make enriched uranium for peaceful nuclear purposes. Other countries have secretly sought centrifuges to make highly enriched uranium for nuclear weapons. In more recent times, several countries have secretly sought or built gas centrifuges in regions of tension. The main countries that have been of interest in the last two decades have been Pakistan, Iraq, Iran, and North Korea. Currently, most attention is focused on Iran, Pakistan, and North Korea. These states did not have the indigenous abilities to make gas centrifuges, focusing instead on illicit and questionable foreign procurement. The presentation covered the following main sections: Spread of centrifuges through illicit procurement; Role of export controls in stopping proliferation; Increasing the transparency of gas centrifuge programs in non-nuclear weapon states; and, Verified dismantlement of gas centrifuge programs. Gas centrifuges are important providers of low enriched uranium for civil nuclear power reactors. They also pose special nuclear proliferation risks. We all have special responsibilities to prevent the spread of gas centrifuges into regions of tension and to mitigate the consequences of their spread into the Middle East, South Asia, and North Asia.

  12. Specification and Design Methodologies for High-Speed Fault-Tolerant Array Algorithms and Structures for VLSI.

    DTIC Science & Technology

    1987-06-01

    A182 772 SPECIFICATION AND DESIGN METHODOLOGIES FOR NIGH-SPEED 11 FAULT-TOLERANT ARRA.. CU) CALIFORNIA UNIY LOS ANGELES DEPT OF COMPUTER SCIENCE M D ...ERCEGOVAC ET AL. JUN 0? UNLASSIFIED N611-03--K-S49 F/ 91 ML Ji 1 2. ~ iiii -i ’IfIhIN I_______ IIIII .l n. ’ 3 ’ 3 .3 .5 *. .. w w, - .. .J’. ~ d ...STRUCTURES FOR VLSI Office of Naval Research Contract No. N00014-83-K-0493 Principal Investigator Milo D . Ercegovac ELECTE Co-Principal Ivestigator S AUG 0

  13. Action-Specific Effects in a Social Context: Others' Abilities Influence Perceived Speed

    ERIC Educational Resources Information Center

    Witt, Jessica K.; Sugovic, Mila; Taylor, J. Eric T.

    2012-01-01

    According to the action-specific account of perception, perceivers see the environment relative to their ability to perform the intended action. For example, in a modified version of the computer game Pong, balls that were easier to block looked to be moving slower than balls that were more difficult to block (Witt & Sugovic, 2010). It is unknown,…

  14. Rapid ABO genotyping by high-speed droplet allele-specific PCR using crude samples.

    PubMed

    Taira, Chiaki; Matsuda, Kazuyuki; Takeichi, Naoya; Furukawa, Satomi; Sugano, Mitsutoshi; Uehara, Takeshi; Okumura, Nobuo; Honda, Takayuki

    2017-03-13

    ABO genotyping has common tools for personal identification of forensic and transplantation field. We developed a new method based on a droplet allele-specific PCR (droplet-AS-PCR) that enabled rapid PCR amplification. We attempted rapid ABO genotyping using crude DNA isolated from dried blood and buccal cells. We designed allele-specific primers for three SNPs (at nucleotides 261, 526, and 803) in exons 6 and 7 of the ABO gene. We pretreated dried blood and buccal cells with proteinase K, and obtained crude DNAs without DNA purification. Droplet-AS-PCR allowed specific amplification of the SNPs at the three loci using crude DNA, with results similar to those for DNA extracted from fresh peripheral blood. The sensitivity of the methods was 5%-10%. The genotyping of extracted DNA and crude DNA were completed within 8 and 9 minutes, respectively. The genotypes determined by the droplet-AS-PCR method were always consistent with those obtained by direct sequencing. The droplet-AS-PCR method enabled rapid and specific amplification of three SNPs of the ABO gene from crude DNA treated with proteinase K. ABO genotyping by the droplet-AS-PCR has the potential to be applied to various fields including a forensic medicine and transplantation medical care. © 2017 Wiley Periodicals, Inc.

  15. The American Gas Centrifuge Past, Present, and Future

    SciTech Connect

    Waters, Dean

    2004-09-15

    The art of gas centrifugation was born in 1935 at the University of Virginia when Dr. Jesse Beams demonstrated experimentally the separation of chlorine isotopes using an ultra-high speed centrifuge. Dr. Beam’s experiment initiated work that created a rich history of scientific and engineering accomplishment in the United States in the art of isotope separation and even large scale biological separation by centrifugation. The early history of the gas centrifuge development was captured in a lecture and documented by Dr. Jesse Beams in 1975. Much of Dr. Beams lecture material is used in this paper up to the year 1960. Following work by Dr. Gernot Zippe at the University of Virginia between 1958 and 1960, the US government embarked on a centrifuge development program that ultimately led to the start of construction of the Gas Centrifuge Enrichment Plant in Piketon Ohio in the late 1970’s. The government program was abandoned in 1985 after investing in the construction of two of six planned process buildings, a complete supply chain for process and centrifuge parts, and the successful manufacture and brief operation of an initial complement of production machines that would have met 15 percent of the planned capacity of the constructed process buildings. A declining market for enriched uranium, a glut of uranium enrichment capacity worldwide, and the promise of a new laser based separation process factored in the decision to stop the government program. By the late 1990’s it had become evident that gas centrifugation held the best promise to produce enriched uranium at low cost. In1999, the United States Enrichment Corporation undertook an initiative to revive the best of the American centrifuge technology that had been abandoned fourteen years earlier. This is an exciting story and one that when complete will enable the United States to maintain its domestic supply and to be highly competitive in the world market for this important energy commodity. (auth)

  16. Characteristic analysis on the pressure fluctuation in the impeller of a low specific speed mixed flow pump

    NASA Astrophysics Data System (ADS)

    Zhang, W. W.; Yu, Z. Y.; Zhu, B. S.

    2016-05-01

    To explore the pressure fluctuation characteristics of a low speed specific speed mixed flow pump caused by rotor-stator interaction, the unsteady flow was simulated with CFX for the whole flow passage of a mixed flow pump with a specific speed of 148.8. The structured mesh of the computation domain was generated with ICEM CFD and TurboGrid, and mesh-independent analysis was done in the design condition. Through the comparison with the experiment data, the reliability of the simulation was verified. In different locations of the impeller passage, monitoring points were set. With Fast Fourier Transform (FFT), the characteristic analysis on the pressure fluctuation in the impeller passage was done for three flow rate conditions (0.75Qd, Qd, 1.25Qd). The results show that the pressure fluctuation amplitude increases from the inlet to the outlet. And the maximum values in different flow rates exist near the hub of the outlet; The pressure fluctuation is small in the design condition, but the largest in the small flow rate condition, accompanied by the secondary dominant frequencies with large amplitudes; In the small flow rate condition and design condition, the dominant frequency varies from the inlet to the outlet because the combine action of the impeller and guide vane; while in the large flow rate condition, the pressure fluctuation in the whole impeller passage is affected significantly by the guide vane, and the domain frequency is 8 times the rotational frequency of impeller. In addition, the change of pressure fluctuation from the pressure surface to the suction surface in the off-design conditions is investigated, and the results demonstrates that the intensity of the pressure fluctuation in the impeller passage is closely related with the impeller as well as the distribution of the vorticity and the pressure.

  17. Quasi-three dimensional hydraulic design and performance calculation of high specific speed mixed-flow pump

    NASA Astrophysics Data System (ADS)

    Su, M.; Zhang, Y. X.; Zhang, J. Y.; Hou, H. C.

    2016-05-01

    According to the basic parameters of 211-80 high specific speed mixed-flow pump, based on the quasi-three dimensional flow theory, the hydraulic design of impeller and its matching spaced guide vanes for high specific speed mixed flow pump was completed, in which the iterative calculation of S 1, S 2 stream surfaces was employed to obtain meridional flow fields and the point-by-point integration method was employed to draw blade camber lines. Blades are thickened as well as blade leading edges are smoothed in the conformal mapping surface. Subsequently the internal fields of the whole flow passage of the designed pump were simulated by using RANS equations with RNG k-ε two-equation turbulent model. The results show that, compared with the 211-80 model, the hydraulic efficiency of the designed pump at the optimal flow rate increases 9.1%. The hydraulic efficiency of designed pump in low flow rate condition (78% designed flow rate) increases 6.46%. The hydraulic efficiency in high flow rate areas increases obviously and there is no bad phenomenon of suddenly decrease of hydraulic efficiency in model pump. From the distributions of velocity and pressure fields, it can be seen that the flow in impeller is uniform and the increase of pressure is gentle. There are no obvious impact phenomenon on impeller inlet and obvious wake shedding vortex phenomenon from impeller outlet to guide vanes inlet.

  18. Pea Chaperones under Centrifugation

    NASA Astrophysics Data System (ADS)

    Talalaiev, Oleksandr

    2008-06-01

    Etiolated Pisum sativum seedlings were subjected to altered g-forces by centrifugation (3-14g). By using semiquantitative RT-PCR, we studied transcripts of pea genes coding for chaperones that are representatives of small heat shock proteins (sHsps) family. Four members from the different classes of sHsps: cytosolic Hsp17.7 and Hsp18.1 (class I and class II accordingly), chloroplast Hsp21 (class III) and endoplasmic reticulum Hsp22.7 (class IV) were investigated. We conclude that exposure to 3, 7, 10 and 14g for 1h did not affect the level of sHsp transcripts.

  19. Centrifugal Adsorption Cartridge System

    NASA Technical Reports Server (NTRS)

    Gonda, Steve R.; Tsao, Yow-Min D.; Lee, Wenshan

    2004-01-01

    The centrifugal adsorption cartridge system (CACS) is an apparatus that recovers one or more bioproduct(s) from a dilute aqueous solution or suspension flowing from a bioreactor. The CACS can be used both on Earth in unit gravity and in space in low gravity. The CACS can be connected downstream from the bioreactor; alternatively, it can be connected into a flow loop that includes the bioreactor so that the liquid can be recycled. A centrifugal adsorption cartridge in the CACS (see figure) includes two concentric cylinders with a spiral ramp between them. The volume between the inner and outer cylinders, and between the turns of the spiral ramp is packed with an adsorbent material. The inner cylinder is a sieve tube covered with a gas-permeable, hydrophobic membrane. During operation, the liquid effluent from the bioreactor is introduced at one end of the spiral ramp, which then constrains the liquid to flow along the spiral path through the adsorbent material. The spiral ramp also makes the flow more nearly uniform than it would otherwise be, and it minimizes any channeling other than that of the spiral flow itself. The adsorbent material is formulated to selectively capture the bioproduct(s) of interest. The bioproduct(s) can then be stored in bound form in the cartridge or else eluted from the cartridge. The centrifugal effect of the spiral flow is utilized to remove gas bubbles from the liquid. The centrifugal effect forces the bubbles radially inward, toward and through the membrane of the inner cylinder. The gas-permeable, hydrophobic membrane allows the bubbles to enter the inner cylinder while keeping the liquid out. The bubbles that thus enter the cylinder are vented to the atmosphere. The spacing between the ramps determines rate of flow along the spiral, and thereby affects the air-bubble-removal efficiency. The spacing between the ramps also determines the length of the fluid path through the cartridge adsorbent, and thus affects the bioproduct

  20. Centrifugal-reciprocating compressor

    NASA Technical Reports Server (NTRS)

    Higa, W. H. (Inventor)

    1984-01-01

    A centrifugal compressor is described which includes at least one pair of cylinders arranged in coaxial alignment and supported for angular displacement about a common axis of rotation normally disecting a common longitudinal axis of symmetry for the cylinders. The cylinders are characterized by ported closures located at the mutually remote ends thereof through which the cylinders are charged and discharged, and a pair of piston heads seated within the cylinders and supported for floating displacement in compressive strokes in response to unidirectional angular displacement imparted to the cylinders.

  1. Experimental Investigation of Centrifugal Compressor Stabilization Techniques

    NASA Technical Reports Server (NTRS)

    Skoch, Gary J.

    2003-01-01

    Results from a series of experiments to investigate techniques for extending the stable flow range of a centrifugal compressor are reported. The research was conducted in a high-speed centrifugal compressor at the NASA Glenn Research Center. The stabilizing effect of steadily flowing air-streams injected into the vaneless region of a vane-island diffuser through the shroud surface is described. Parametric variations of injection angle, injection flow rate, number of injectors, injector spacing, and injection versus bleed were investigated for a range of impeller speeds and tip clearances. Both the compressor discharge and an external source were used for the injection air supply. The stabilizing effect of flow obstructions created by tubes that were inserted into the diffuser vaneless space through the shroud was also investigated. Tube immersion into the vaneless space was varied in the flow obstruction experiments. Results from testing done at impeller design speed and tip clearance are presented. Surge margin improved by 1.7 points using injection air that was supplied from within the compressor. Externally supplied injection air was used to return the compressor to stable operation after being throttled into surge. The tubes, which were capped to prevent mass flux, provided 9.3 points of additional surge margin over the baseline surge margin of 11.7 points.

  2. Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain.

    PubMed

    Pirazzini, Marco; Henke, Tina; Rossetto, Ornella; Mahrhold, Stefan; Krez, Nadja; Rummel, Andreas; Montecucco, Cesare; Binz, Thomas

    2013-11-29

    Botulinum neurotoxins translocate their enzymatic domain across vesicular membranes. The molecular triggers of this process are unknown. Here, we tested the possibility that this is elicited by protonation of conserved surface carboxylates. Glutamate-48, glutamate-653 and aspartate-877 were identified as possible candidates and changed into amide. This triple mutant showed increased neurotoxicity due to faster cytosolic delivery of the enzymatic domain; membrane translocation could take place at less acidic pH. Thus, neutralisation of specific negative surface charges facilitates membrane contact permitting a faster initiation of the toxin membrane insertion.

  3. Centrifuge impact cratering experiment 5

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Transient crates motions, cratering flow fields, crates dynamics, determining impact conditions from total crater welt, centrifuge quarter-space cratering, and impact cratering mechanics research is documented.

  4. Latex Micro-balloon Pumping in Centrifugal Microfluidic Platforms

    PubMed Central

    Aeinehvand, Mohammad Mahdi; Ibrahim, Fatimah; Al-Faqheri, Wisam; Thio, Tzer Hwai Gilbert; Kazemzadeh, Amin; Wadi harun, Sulaiman; Madou, Marc

    2014-01-01

    Centrifugal microfluidic platforms have emerged as point-of-care diagnostic tools. However, the unidirectional nature of the centrifugal force limits the available space for multi-stepped processes on a single microfluidics disc. To overcome this limitation, a passive pneumatic pumping method actuated at high rotational speeds has been previously proposed to pump liquid against the centrifugal force. In this paper, a novel micro-balloon pumping method that relies on elastic energy stored in a latex membrane is introduced. It operates at low rotational speeds and pumps a larger volume of liquid towards the centre of the disc. Two different micro-balloon pumping designs have been developed to study the pump performance and capacity at a range of rotational frequencies from 0 to 1500 rpm. The behaviour of the micro-balloon pump on the centrifugal microfluidic platforms has been theoretically analysed and compared with the experimental data. The experimental data shows that, the developed pumping method dramatically decreases the required rotational speed to pump liquid compared to the previously developed pneumatic pumping methods. It also shows that within a range of rotational speed, desirable volume of liquid can be stored and pumped by adjusting the size of the micro-balloon. PMID:24441792

  5. Measurements of the rotordynamic shroud forces for centrifugal pumps

    NASA Technical Reports Server (NTRS)

    Guinzburg, A.; Brennen, C. E.; Acosta, A. J.; Caughey, T. K.

    1990-01-01

    An experiment was designed to measure the rotordynamic shroud forces on a centrifugal pump impeller. The measurements were done for various whirl/impeller speed ratios and for different flow rates. A destabilizing tangential force was measured for small positive whirl ratios and this force decreased with increasing flow rate.

  6. Prediction of performance of centrifugal pumps during starts under pressure

    NASA Technical Reports Server (NTRS)

    Rostafinski, W.

    1969-01-01

    Method which calculates start-up characteristics of centrifugal pumps reveals a capacity to predict pressure drop characteristics of pumps with vaned diffusers. Calculations are based on pump geometry, design-point flow, speed, and pressure rise, and the pump characteristic within range of approximately ten percent of the design-point flow.

  7. Latex micro-balloon pumping in centrifugal microfluidic platforms.

    PubMed

    Aeinehvand, Mohammad Mahdi; Ibrahim, Fatimah; Harun, Sulaiman Wadi; Al-Faqheri, Wisam; Thio, Tzer Hwai Gilbert; Kazemzadeh, Amin; Madou, Marc

    2014-03-07

    Centrifugal microfluidic platforms have emerged as point-of-care diagnostic tools. However, the unidirectional nature of the centrifugal force limits the available space for multi-step processes on a single microfluidic disc. To overcome this limitation, a passive pneumatic pumping method actuated at high rotational speeds has been previously proposed to pump liquid against the centrifugal force. In this paper, a novel micro-balloon pumping method that relies on elastic energy stored in a latex membrane is introduced. It operates at low rotational speeds and pumps a larger volume of liquid towards the centre of the disc. Two different micro-balloon pumping mechanisms have been designed to study the pump performance at a range of rotational frequencies from 0 to 1500 rpm. The behaviour of the micro-balloon pump on the centrifugal microfluidic platforms has been theoretically analysed and compared with the experimental data. The experimental data show that the developed pumping method dramatically decreases the required rotational speed to pump liquid compared to the previously developed pneumatic pumping methods. It also shows that within a range of rotational speed, a desirable volume of liquid can be stored and pumped by adjusting the size of the micro-balloon.

  8. Measurements of the rotordynamic shroud forces for centrifugal pumps

    NASA Technical Reports Server (NTRS)

    Guinzburg, A.; Brennen, C. E.; Acosta, A. J.; Caughey, T. K.

    1990-01-01

    An experiment was designed to measure the rotordynamic shroud forces on a centrifugal pump impeller. The measurements were done for various whirl/impeller speed ratios and for different flow rates. A destabilizing tangential force was measured for small positive whirl ratios and this force decreased with increasing flow rate.

  9. Centrifugal shot blast system

    SciTech Connect

    1998-02-01

    This report describes a demonstration of Concrete cleaning, Inc., modified centrifugal shot blast technology to remove the paint coating from concrete flooring. This demonstration is part of the Chicago Pile-5 (CP-5) Large-Scale Demonstration Project (LSDP) sponsored by the US Department of Energy (DOE), office of Science and Technology (OST), Deactivation and Decommissioning Focus Area (DDFA). The objective of the LSDP is to select and demonstrate potentially beneficial technologies at the Argonne National Laboratory-East (ANL) CP-5 Research Reactor. The purpose of the LSDP is to demonstrate that using innovative and improved decontamination and decommissioning (D and D) technologies from various sources can result in significant benefits, such as decreased cost and increased health and safety, as compared with baseline D and D technologies. Potential markets exist for the innovative centrifugal shot blast system at the following sites: Fernald Environmental Management Project, Los Alamos, Nevada, Oak Ridge Y-12 and K-25, Paducah, Portsmouth Gaseous Diffusion site, and the Savannah River Site. This information is based on a revision to the OST Linkage Tables dated August 4, 1997.

  10. Centrifugal precipitation chromatography.

    PubMed

    Ito, Yoichiro; Qi, Lin

    2010-01-15

    Centrifugal precipitation chromatography separates analytes according their solubility in ammonium sulfate (AS) solution and other precipitants. The separation column is made from a pair of long spiral channels partitioned with a semipermeable membrane. In a typical separation, concentrated ammonium sulfate is eluted through one channel while water is eluted through the other channel in the opposite direction. This countercurrent process forms an exponential AS concentration gradient through the water channel. Consequently, protein samples injected into the water channel is subjected to a steadily increasing AS concentration and at the critical AS concentration they are precipitated and deposited in the channel bed by the centrifugal force. Then the chromatographic separation is started by gradually reducing the AS concentration in the AS channel which lowers the AS gradient concentration in the water channel. This results in dissolution of deposited proteins which are again precipitated at an advanced critical point as they move through the channel. Consequently, proteins repeat precipitation and dissolution through a long channel and finally eluted out from the column in the order of their solubility in the AS solution. The present method has been successfully applied to a number of analytes including human serum proteins, recombinant ketosteroid isomerase, carotenoid cleavage enzymes, plasmid DNA, polysaccharide, polymerized pigments, PEG-protein conjugates, etc. The method is capable to single out the target species of proteins by affinity ligand or immunoaffinity separation.

  11. Engineering design of centrifugal casting machine

    NASA Astrophysics Data System (ADS)

    Kusnowo, Roni; Gunara, Sophiadi

    2017-06-01

    Centrifugal casting is a metal casting process in which metal liquid is poured into a rotating mold at a specific temperature. Given round will generate a centrifugal force that will affect the outcome of the casting. Casting method is suitable in the manufacture of the casting cylinder to obtain better results. This research was performed to design a prototype machine by using the concept of centrifugal casting. The design method was a step-by-step systematic approach in the process of thinking to achieve the desired goal of realizing the idea and build bridges between idea and the product. Design process was commenced by the conceptual design phase and followed by the embodiment design stage and detailed design stage. With an engineering design process based on the method developed by G. E. Dieter, draft prototype of centrifugal casting machine with dimension of 550×450×400 mm, ¼ HP motor power, pulley and belt mechanism, diameter of 120-150mm, simultaneously with the characteristics of simple casting product, easy manufacture and maintenance, and relatively inexpensive, was generated.

  12. Relationship between Insulin-Resistance Processing Speed and Specific Executive Function Profiles in Neurologically Intact Older Adults.

    PubMed

    Frazier, Darvis T; Bettcher, Brianne M; Dutt, Shubir; Patel, Nihar; Mungas, Dan; Miller, Joshua; Green, Ralph; Kramer, Joel H

    2015-09-01

    This study investigated the relationship between insulin-resistance and constituent components of executive function in a sample of neurologically intact older adult subjects using the homeostasis model assessment (HOMA-IR) and latent factors of working memory, cognitive control and processing speed derived from confirmatory factor analysis. Low-density lipoprotein (LDL), mean arterial pressure (MAP), along with body mass index (BMI) and white matter hypointensity (WMH) were used to control for vascular risk factors, adiposity and cerebrovascular injury. The study included 119 elderly subjects recruited from the University of California, San Francisco Memory and Aging Center. Subjects underwent neuropsychological assessment, fasting blood draw and brain magnetic resonance imaging (MRI). Partial correlations and linear regression models were used to examine the HOMA-IR-executive function relationship. Pearson correlation adjusting for age showed a significant relationship between HOMA-IR and working memory (rp = -.18; p = .047), a trend with cognitive control (rp = -.17; p = .068), and no relationship with processing speed (rp = .013; p = .892). Linear regression models adjusting for demographic factors (age, education, and gender), LDL, MAP, BMI, and WMH indicated that HOMA-IR was negatively associated with cognitive control (r = -.256; p = .026) and working memory (r = -.234; p = .054). These results suggest a greater level of peripheral insulin-resistance is associated with decreased cognitive control and working memory. After controlling for demographic factors, vascular risk, adiposity and cerebrovascular injury, HOMA-IR remained significantly associated with cognitive control, with working memory showing a trend. These findings substantiate the insulin-resistance-executive function hypothesis and suggest a complex interaction, demonstrated by the differential impact of insulin-resistance on processing speed and specific aspects of executive function.

  13. Centrifugal casting of ZA8 zinc alloy and composite A356/silicon carbide: Study and modeling of phases' and particles' segregation

    NASA Astrophysics Data System (ADS)

    Balout, Bahaa

    Centrifugation is a casting technology that allows the production of cylindrical and graduated parts with different mechanical properties through the section. The need for materials with good quality and specific mechanical properties has been driven this technology in order to produce different types of materials such as zinc alloys and graduated metal matrix composites reinforced by hard and wear resistant particles. The goal of this research project is to study and model the eutectic macrosegregation, the solidification speed, and the speeds of solidification fronts during centrifugal casting of ZA8 zinc-aluminum alloy in order to improve the part quality and increase its strength and field reliability. Moreover, the segregation of the particles during centrifugal casting of an aluminum matrix composite reinforced by silicon carbide particles (A356/SiC) is also studied to improve and control the graduation of the parts. The cooling rate, the speed, acceleration/deceleration, displacement, and segregation of the particles across the section will be modeled by discretization of Stokes' law in time in order to take into consideration the change in the centrifugal radius and melt viscosity during cooling process. This study will allow the control of the graduation degree of particles across the section in order to improve the properties and wear resistance of the composite. This composite can be used in systems where friction is critical and load is high (reinforcements of parts for the cylinders of pneumatic systems). The results show that the maximum macrosegregation zone of the eutectic across the casting section corresponds to the last point of solidification. The eutectic macrosegregation produced during centrifugal casting of thin walled part is a normal segregation which varies depending on the solidification speed and the ratio between the speeds of solidification fronts. On the other hand, it was found that the position and volume fraction of the particles

  14. Centrifuge treatment of coal tar

    SciTech Connect

    L.A. Kazak; V.Z. Kaidalov; L.F. Syrova; O.S. Miroshnichenko; A.S. Minakov

    2009-07-15

    New technology is required for the removal of water and heavy fractions from regular coal tar. Centrifuges offer the best option. Purification of coal tar by means of centrifuges at OAO NLMK permits the production of pitch coke or electrode pitch that complies with current standards.

  15. Exosome enrichment of human serum using multiple cycles of centrifugation.

    PubMed

    Kim, Jeongkwon; Tan, Zhijing; Lubman, David M

    2015-09-01

    In this work, we compared the use of repeated cycles of centrifugation at conventional speeds for enrichment of exosomes from human serum compared to the use of ultracentrifugation (UC). After removal of cells and cell debris, a speed of 110 000 × g or 40 000 × g was used for the UC or centrifugation enrichment process, respectively. The enriched exosomes were analyzed using the bicinchoninic acid assay, 1D gel separation, transmission electron microscopy, Western blotting, and high-resolution LC-MS/MS analysis. It was found that a five-cycle repetition of UC or centrifugation is necessary for successful removal of nonexosomal proteins in the enrichment of exosomes from human serum. More significantly, 5× centrifugation enrichment was found to provide similar or better performance than 5× UC enrichment in terms of enriched exosome protein amount, Western blot band intensity for detection of CD-63, and numbers of identified exosome-related proteins and cluster of differentiation (CD) proteins. A total of 478 proteins were identified in the LC-MS/MS analyses of exosome proteins obtained from 5× UCs and 5× centrifugations including many important CD membrane proteins. The presence of previously reported exosome-related proteins including key exosome protein markers demonstrates the utility of this method for analysis of proteins in human serum.

  16. Experimental analysis of centrifugal dewatering process of polyelectrolyte flocculated waste activated sludge.

    PubMed

    Chu, C P; Lee, D J

    2001-07-01

    The study experimentally investigated the centrifugal separation of moisture from activated sludge subject to cationic polyelectrolyte flocculation. An arm-suspended centrifuge was employed which allowed in-situ detection on all positions of interfaces of centrifuged sludge as functions of time. Experimental results revealed that, sludge flocculation would yield a significant sedimentation effect at the first phase of centrifugation. Therefore, not as suggested in conventional centrifugal-filtration models, the most significant moisture-removal stages included filtrate to flow through a wet cake. Moreover, an optimal rotational speed exists at which the moisture-removal rate reaches a maximum value. New theories/correlations are required to describe centrifugation dewatering of polyelectrolyte flocculated sludge.

  17. Rat growth during chronic centrifugation

    NASA Technical Reports Server (NTRS)

    Pitts, G. C.; Oyama, J.

    1978-01-01

    Female weanling rats were chronically centrifuged at 4.15 G with controls at terrestrial gravity. Samples were sacrificed for body composition studies at 0, 28, 63, 105 and 308 days of centrifugation. The centrifuged group approached a significantly lower mature body mass than the controls (251 and 318g) but the rate of approach was the same in both groups. Retirement to 1G on the 60th day resulted in complete recovery. Among individual components muscle, bone, skin, CNS, heart, kidneys, body water and body fat were changed in the centrifuged group. However, an analysis of the growth of individual components relative to growth of the total fat-free compartment revealed that only skin (which increased in mass) was responding to centrifugation per se.

  18. Rat growth during chronic centrifugation

    NASA Technical Reports Server (NTRS)

    Pitts, G. C.; Oyama, J.

    1978-01-01

    Female weanling rats were chronically centrifuged at 4.15 G with controls at terrestrial gravity. Samples were sacrificed for body composition studies at 0, 28, 63, 105 and 308 days of centrifugation. The centrifuged group approached a significantly lower mature body mass than the controls (251 and 318g) but the rate of approach was the same in both groups. Retirement to 1G on the 60th day resulted in complete recovery. Among individual components muscle, bone, skin, CNS, heart, kidneys, body water and body fat were changed in the centrifuged group. However, an analysis of the growth of individual components relative to growth of the total fat-free compartment revealed that only skin (which increased in mass) was responding to centrifugation per se.

  19. Aerodynamically induced radial forces in a centrifugal gas compressor. Part 1: Experimental measurement

    SciTech Connect

    Moore, J.J.; Flathers, M.B.

    1998-04-01

    Net radial loading arising from asymmetric pressure fields in the volutes of centrifugal pumps during off-design operation is well known and has been studied extensively. In order to achieve a marked improvement in overall efficiency in centrifugal gas compressors, vaneless volute diffusers are matched to specific impellers to yield improved performance over a wide application envelope. As observed in centrifugal pumps, nonuniform pressure distributions that develop during operation above and below the design flow create static radial loads on the rotor. In order to characterize these radial forces, a novel experimental measurement and post-processing technique is employed that yields both the magnitude and direction of the load by measuring the shaft centerline locus in the tilt-pad bearings. The method is applicable to any turbomachinery operating on fluid film radial bearings equipped with proximity probes. The forces are found to be a maximum near surge and increase with higher pressures and speeds. The results are nondimensionalized, allowing the radial loading for different operating conditions to be predicted.

  20. Investigation of the Flow Field and Performances of a Centrifugal Pump at Part Load

    NASA Astrophysics Data System (ADS)

    Prunières, R.; Inoue, Y.; Nagahara, T.

    2016-11-01

    Centrifugal pump performance curve instability, characterized by a local dent at part load, can be the consequence of flow instabilities in rotating or stationary parts. Such flow instabilities often result in abnormal operating conditions which can damage both the pump and the system. In order for the pump to have reliable operation over a wide flow rate range, it is necessary to achieve a design free of instability. The present paper focuses on performance curve instability of a centrifugal pump of mid specific speed (ωs = 0.65) for which instability was observed at part load during tests. The geometry used for this research consist of the first stage of a multi-stage centrifugal pump and is composed of a suction bend, a closed-type impeller, a vaned diffuser and return guide vanes. In order to analyse the instability phenomenon, PIV and CFD analysis were performed. Both methods qualitatively agree relatively well. It appears that the main difference before and after head drop is an increase of reverse flow rate at the diffuser passage inlet on the hub side. This reverse flow decreases the flow passing area at the diffuser passage inlet, disallowing effective flow deceleration and impairing static pressure recovery.

  1. Immunoaffinity centrifugal precipitation chromatography.

    PubMed

    Qi, Lin; Ito, Yoichiro

    2007-06-01

    Purification of proteins based on immunoaffinity has been performed using a solid support coated with antibody against the target proteins. The method requires immobilizing the antibody onto the solid support using protein A or G, and has a risk of adsorptive loss of target proteins onto the solid support. Centrifugal precipitation chromatography has been successfully used to purify enzymes, such as ketosteroid isomerase and hyaluronidase without the use of solid support. The purpose of this study is to demonstrate that immunoaffinity centrifugal precipitation chromatography is capable of isolating an antigen by exploiting antigen-antibody binding. The separation was initiated by filling both channels with 40% saturated ammonium sulfate (AS) of pH 4-4.5 followed by loading 20 microl of human plasma (National Institutes of Health blood bank) mixed with 2 mg of rabbit anti-HSA (human serum protein) antibody (Sigma). Then, the sample channel was eluted with water at 0.03 ml/min and AS channel with 40% AS solution of pH 4-4.5 at 1 ml/min until all non-binding components were eluted. Then, the releasing reagent (50% AS solution containing 0.5 M glycine and 10% ammonium hydroxide at pH 10) was introduced through the AS channel to release the target protein (HSA). The retained antibody was recovered by eluting the sample channel with water at 1 ml/min. A hollow fiber membrane device at the outlet (MicroKros, Spectrum, New Brunswick, NJ, USA) was provided on-line dialysis of the eluent before fractions were collected, so that the fractions could be analyzed by SDS-PAGE (sodium dodecyl sulfate - polyacrylamide gel electrophoresis) without further dialysis. The current method does not require immobilizing the antibody onto a matrix, which is used by the conventional immunoaffinity chromatography. This method ensures full recovery of the antigen and antibody, and it may be applied to purification of other proteins.

  2. The Digit Naming Speed Test: Its Power and Incremental Validity in Identifying Children with Specific Reading Disabilities.

    ERIC Educational Resources Information Center

    Davis, John M.; Spring, Carl

    1990-01-01

    Conducted two studies to examine usefulness of Digit Naming Speed Test in diagnostic battery to assess reading disabilities. In first study, Digit Naming Speed Test significantly differentiated male elementary school disabled readers from age-matched boys reading at appropriate grade levels. In second study, Digit Naming Speed Test accounted for…

  3. Numerical simulation of centrifugal casting of pipes

    NASA Astrophysics Data System (ADS)

    Kaschnitz, E.

    2012-07-01

    A numerical simulation model for the horizontal centrifugal pipe casting process was developed with the commercial simulation package Flow3D. It considers - additionally to mass, energy and momentum conservation equations and free surface tracking - the fast radial and slower horizontal movement of the mold. The iron inflow is not steady state but time dependent. Of special importance is the friction between the liquid and the mold in connection with the viscosity and turbulence of the iron. Experiments with the mold at controlled revolution speeds were carried out using a high-speed camera. From these experiments friction coefficients for the description of the interaction between mold and melt were obtained. With the simulation model, the influence of typical process parameters (e.g. melts inflow, mold movement, melt temperature, cooling media) on the wall thickness of the pipes can be studied. The comparison to results of pipes from production shows a good agreement between simulation and reality.

  4. [Hemodynamic analysis of a centrifugal blood pump].

    PubMed

    Wang, Yang; Yang, Ming; Xu, Zihao; Zhuang, Xiaoqi; Li, Qilei; Xu, Liang

    2015-01-01

    This paper built the mathematical model of a centrifugal blood pump, which was designed by ourselves, combined it with that of the human cardiovascular system and simulated the coupling system using Matlab. Then we set up the experiment platform, linked the blood pump to mock human cardiovascular system in case of three-stage heart failure, and measured aortic pressure and flow under different speed. The comparison between experiment results and simulation results not only indicates the coupling model is correct and the blood pump works well, but also shows that with the increase of blood pump speed, the pulsation of aortic pressure and flow will be reduced, this situation will affect the structure and function of blood vessels.

  5. Centrifugally Stimulated Exospheric Ion Escape at Mercury

    NASA Technical Reports Server (NTRS)

    Delcourt, Dominique; Seki, K.; Terada, N.; Moore, Thomas E.

    2012-01-01

    We investigate the transport of ions in the low-altitude magnetosphere magnetosphere of Mercury. We show that, because of small spatial scales, the centrifugal effect due to curvature of the E B drift paths can lead to significant particle energization in the parallel direction. We demonstrate that because of this effect, ions with initial speed smaller than the escape speed such as those produced via thermal desorption can overcome gravity and escape into the magnetosphere. The escape route of this low-energy exosphere originating material is largely controlled by the magnetospheric convection rate. This escape route spreads over a narrower range of altitudes when the convection rate increases. Bulk transport of low-energy planetary material thus occurs within a limited region of space once moderate magnetospheric convection is established. These results suggest that, via release of material otherwise gravitationally trapped, the E B related centrifugal acceleration is an important mechanism for the net supply of plasma to the magnetosphere of Mercury.

  6. On the characteristics of centrifugal-reciprocating machines. [cryogenic coolers

    NASA Technical Reports Server (NTRS)

    Higa, W. H.

    1980-01-01

    A method of compressing helium gas for cryogenic coolers is presented which uses centrifugal force to reduce the forces on the connecting rod and crankshaft in the usual reciprocating compressor. This is achieved by rotating the piston-cylinder assembly at a speed sufficient for the centrifugal force on the piston to overcome the compressional force due to the working fluid. The rotating assembly is dynamically braked in order to recharge the working space with fluid. The intake stroke consists of decelerating the rotating piston-cylinder assembly and the exhaust stroke consists of accelerating the assembly.

  7. Numerical Simulation and Cold Modeling experiments on Centrifugal Casting

    NASA Astrophysics Data System (ADS)

    Keerthiprasad, Kestur Sadashivaiah; Murali, Mysore Seetharam; Mukunda, Pudukottah Gopaliengar; Majumdar, Sekhar

    2011-02-01

    In a centrifugal casting process, the fluid flow eventually determines the quality and characteristics of the final product. It is difficult to study the fluid behavior here because of the opaque nature of melt and mold. In the current investigation, numerical simulations of the flow field and visualization experiments on cold models have been carried out for a centrifugal casting system using horizontal molds and fluids of different viscosities to study the effect of different process variables on the flow pattern. The effects of the thickness of the cylindrical fluid annulus formed inside the mold and the effects of fluid viscosity, diameter, and rotational speed of the mold on the hollow fluid cylinder formation process have been investigated. The numerical simulation results are compared with corresponding data obtained from the cold modeling experiments. The influence of rotational speed in a real-life centrifugal casting system has also been studied using an aluminum-silicon alloy. Cylinders of different thicknesses are cast at different rotational speeds, and the flow patterns observed visually in the actual castings are found to be similar to those recorded in the corresponding cold modeling experiments. Reasonable agreement is observed between the results of numerical simulation and the results of cold modeling experiments with different fluids. The visualization study on the hollow cylinders produced in an actual centrifugal casting process also confirm the conclusions arrived at from the cold modeling experiments and numerical simulation in a qualitative sense.

  8. The simulation and performance of a centrifugal chiller

    NASA Astrophysics Data System (ADS)

    Jackson, W. L.; Chen, F. C.; Hwang, B. C.

    A computer simulation model was developed to analyze the performance of a water-cooled centrifugal chiller. The model is based on a heat pump thermodynamic cycle and empirical correlations for the performance of the system components. The system simulated is composed of a variable-speed centrifugal compressor with a hot-gas bypass option for capacity control, two shell-and-tube heat exchangers, and an expansion device. The model was validated and calibrated against the experimental test results of a 125-ton chiller. The performance of a similar chiller system at various operating conditions and design modifications was analyzed. System performance comparisons were made between a baseline case, cases with high-performance heat exchanger tubes and compressor motor, and various variable-speed compressor operating strategies. It was found that significant performance improvement can be realized by using variable-speed drive and on-demand control strategy.

  9. Aerodynamic and mechanical design of an 8:1 pressure ratio centrifugal compressor

    NASA Technical Reports Server (NTRS)

    Osborne, C.; Runstadler, P. W., Jr.; Stacy, W. D.

    1974-01-01

    A high-pressure-ratio, low-mass-flow centrifugal compressor stage was designed, fabricated, and tested. The design followed specifications that the stage be representative of state-of-the-art performance and that the stage is to be used as a workhorse compressor for planned experiments using laser Doppler velocimeter equipment. The final design is a 75,000-RPM, 19-blade impeller with an axial inducer and 30 degrees of backward leaning at the impeller tip. The compressor design was tested for two- and/or quasi-three-dimensional aerodynamic and stress characteristics. Critical speed analyses were performed for the high speed rotating impeller assembly. An optimally matched, 17-channel vane island diffuser was also designed and built.

  10. Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation.

    PubMed

    Rashid, Mamunur; Belmont, Judson; Carpenter, David; Turner, Christopher E; Olson, Eric C

    2017-09-21

    Paxillin and Hic-5 are homologous focal adhesion adaptor proteins that coordinate cytoskeletal rearrangements in response to integrin-signaling, but their role(s) in cortical development are unknown. Here, we find that Hic-5 deficient mice are postnatal viable with normal cortical layering. Mice with a neural-specific deletion of paxillin are also postnatal viable, but show evidence of a cortical neuron migration delay that is evident pre and perinatally, but is not detected at postnatal day 35 (P35). This phenotype is not modified by Hic-5 deficiency (double knockout). Specific deletion of paxillin in postmitotic neurons by Nex-Cre mediated recombination as well as in utero electroporation of a Cre-expression construct identified a cell-autonomous requirement for paxillin in migrating neurons. Paxillin-deficient neurons have shorter leading processes that exhibited multiple swellings in comparison to control. Multiphoton imaging revealed that paxillin-deficient neurons migrate ∼30% slower than control neurons. This phenotype is similar to that produced by deletion of focal adhesion kinase (FAK), a signaling partner of paxillin and suggests paxillin and FAK function cell autonomously to control migrating neuron morphology and speed during cortical development. © 2017. Published by The Company of Biologists Ltd.

  11. Waves in Strong Centrifugal Field

    NASA Astrophysics Data System (ADS)

    Bogovalov, S. V.; Kislov, V. A.; Tronin, I. V.

    Dynamics of waves generated by scopes in gas centrifuges (GC) for isotope separation is considered. The centrifugal acceleration in the GC reaches values of the order of 106g. The centrifugal and Coriolis forces modify essentially the conventional sound waves. Three families of the waves with different polarization and dispersion exist in these conditions. Dynamics of the flow in the model GC Iguasu is investigated numerically. Comparison of the results of the numerical modeling of the wave dynamics with the analytical predictions is performed. New phenomena of the resonances in the GC is found. The resonances occur for the waves polarized along the rotational axis having the smallest dumping due to the viscosity.

  12. Oil-free centrifugal hydrogen compression technology demonstration

    SciTech Connect

    Heshmat, Hooshang

    2014-05-31

    One of the key elements in realizing a mature market for hydrogen vehicles is the deployment of a safe and efficient hydrogen production and delivery infrastructure on a scale that can compete economically with current fuels. The challenge, however, is that hydrogen, being the lightest and smallest of gases with a lower viscosity and density than natural gas, readily migrates through small spaces and is difficult to compresses efficiently. While efficient and cost effective compression technology is crucial to effective pipeline delivery of hydrogen, the compression methods used currently rely on oil lubricated positive displacement (PD) machines. PD compression technology is very costly, has poor reliability and durability, especially for components subjected to wear (e.g., valves, rider bands and piston rings) and contaminates hydrogen with lubricating fluid. Even so called “oil-free” machines use oil lubricants that migrate into and contaminate the gas path. Due to the poor reliability of PD compressors, current hydrogen producers often install duplicate units in order to maintain on-line times of 98-99%. Such machine redundancy adds substantially to system capital costs. As such, DOE deemed that low capital cost, reliable, efficient and oil-free advanced compressor technologies are needed. MiTi’s solution is a completely oil-free, multi-stage, high-speed, centrifugal compressor designed for flow capacity of 500,000 kg/day with a discharge pressure of 1200 psig. The design employs oil-free compliant foil bearings and seals to allow for very high operating speeds, totally contamination free operation, long life and reliability. This design meets the DOE’s performance targets and achieves an extremely aggressive, specific power metric of 0.48 kW-hr/kg and provides significant improvements in reliability/durability, energy efficiency, sealing and freedom from contamination. The multi-stage compressor system concept has been validated through full scale

  13. Numerical simulation and analysis of solid-liquid two-phase flow in centrifugal pump

    NASA Astrophysics Data System (ADS)

    Zhang, Yuliang; Li, Yi; Cui, Baoling; Zhu, Zuchao; Dou, Huashu

    2013-01-01

    The flow with solid-liquid two-phase media inside centrifugal pumps is very complicated and the relevant method for the hydraulic design is still immature so far. There exist two main problems in the operation of the two-phase flow pumps, i.e., low overall efficiency and severe abrasion. In this study, the three-dimensional, steady, incompressible, and turbulent solid-liquid two-phase flows in a low-specific-speed centrifugal pump are numerically simulated and analyzed by using a computational fluid dynamics (CFD) code based on the mixture model of the two-phase flow and the RNG k- ɛ two-equation turbulence model, in which the influences of rotation and curvature are fully taken into account. The coupling between impeller and volute is implemented by means of the frozen rotor method. The simulation results predicted indicate that the solid phase properties in two-phase flow, especially the concentration, the particle diameter and the density, have strong effects on the hydraulic performance of the pump. Both the pump head and the efficiency are reduced with increasing particle diameter or concentration. However, the effect of particle density on the performance is relatively minor. An obvious jet-wake flow structure is presented near the volute tongue and becomes more remarkable with increasing solid phase concentration. The suction side of the blade is subject to much more severe abrasion than the pressure side. The obtained results preliminarily reveal the characteristics of solid-liquid two-phase flow in the centrifugal pump, and are helpful for improvement and empirical correction in the hydraulic design of centrifugal pumps.

  14. Detection of circulating microparticles by flow cytometry: influence of centrifugation, filtration of buffer, and freezing

    PubMed Central

    Dey-Hazra, Emily; Hertel, Barbara; Kirsch, Torsten; Woywodt, Alexander; Lovric, Svjetlana; Haller, Hermann; Haubitz, Marion; Erdbruegger, Uta

    2010-01-01

    The clinical importance of microparticles resulting from vesiculation of platelets and other blood cells is increasingly recognized, although no standardized method exists for their measurement. Only a few studies have examined the analytical and preanalytical steps and variables affecting microparticle detection. We focused our analysis on microparticle detection by flow cytometry. The goal of our study was to analyze the effects of different centrifugation protocols looking at different durations of high and low centrifugation speeds. We also analyzed the effect of filtration of buffer and long-term freezing on microparticle quantification, as well as the role of Annexin V in the detection of microparticles. Absolute and platelet-derived microparticles were 10- to 15-fold higher using initial lower centrifugation speeds at 1500 × g compared with protocols using centrifugation speeds at 5000 × g (P < 0.01). A clear separation between true events and background noise was only achieved using higher centrifugation speeds. Filtration of buffer with a 0.2 μm filter reduced a significant amount of background noise. Storing samples for microparticle detection at −80°C decreased microparticle levels at days 28, 42, and 56 (P < 0.05 for all comparisons with fresh samples). We believe that staining with Annexin V is necessary to distinguish true events from cell debris or precipitates. Buffers should be filtered and fresh samples should be analyzed, or storage periods will have to be standardized. Higher centrifugation speeds should be used to minimize contamination by smaller size platelets. PMID:21191433

  15. Centrifugal pump impeller

    SciTech Connect

    Lovisetto, P.

    1988-01-19

    An impeller for a centrifugal pump is described comprising: a rotatable impeller shaft; circumferentially spaced vanes mounted for rotation with the impeller shaft, the vanes extending outwardly relative to the impeller shaft and each including first and second axially-spaced edges; first and second axially-spaced cover members for vanes, the cover members being mounted for rotation with the impeller shaft and extending outwardly relative to the axial direction of the impeller shaft, the first cover member being disposed adjacent to the first edges of the vanes and the second cover member being disposed adjacent to the second edges of the vanes so as to provide an impeller chamber between the first and second cover members which is divided into subchambers by the vanes. One of the first and second cover members has a centrally disposed inlet opening therethrough for admitting fluid into the impeller chamber to then be conducted outwardly upon rotation of the impeller shaft; and the fist cover member being so constructed and mounted relative to the vanes that a portion thereof is free to flex axially away from respective portions of the first edges of the vanes in response to fluid pressure pulsations within the impeller chamber to temporarily increase the distance between the portion of the first cover and the respective portions of the first edges of the vanes.

  16. Modified Centrifugal Compressor

    DTIC Science & Technology

    1974-11-01

    surface area, and friction coefficient for bladed disks. 43 SECTION VI VALIDATION OF TEST DATA Estimates of the uncertainty of the data acquired from...Total Temperature __i_ m jhrond Watt - 20 P.MO ipoim. THRVEL CHESI Figure A-10. Inducer Exit Traverse; 99% Speed, 0-deg IGV, Run 9. 03. 74 Figure

  17. HOUSINGS AND MOUNTINGS FOR CENTRIFUGES

    DOEpatents

    Rushing, F.C.

    1960-08-16

    A protective housing for a gas centrifuge comprises a slidable connection between flanges and framework portions for absorbing rotational energy in case of bursting of the rotor and a sealing means for sealing the rotor chamber.

  18. Centrifugal dryers keep pace with the market

    SciTech Connect

    Fiscor, S.

    2008-03-15

    New plant design and upgrades create a shift in dewatering strategies. The article describes recent developments. Three major manufacturers supply centrifugal dryers - TEMA, Centrifugal & Mechanical Industries (CMI) and Ludowici. CMI introduced a line of vertical centrifugal dryers. TEMA improved the techniques by developing a horizontal vibratory centrifuge (HVC) which simplified maintenance. 3 figs., 1 photo.

  19. Microwave assisted centrifuge and related methods

    DOEpatents

    Meikrantz, David H [Idaho Falls, ID

    2010-08-17

    Centrifuge samples may be exposed to microwave energy to heat the samples during centrifugation and to promote separation of the different components or constituents of the samples using a centrifuge device configured for generating microwave energy and directing the microwave energy at a sample located in the centrifuge.

  20. Control of centrifugal blood pump based on the motor current.

    PubMed

    Iijima, T; Inamoto, T; Nogawa, M; Takatani, S

    1997-07-01

    In this study, centrifugal pump performance was examined in a mock circulatory loop to derive an automatic pump rotational speed (rpm) control method. The pivot bearing supported sealless centrifugal pump was placed in the left ventricular apex to aorta bypass mode. The pneumatic pulsatile ventricle was used to simulate the natural ventricle. To simulate the suction effect in the ventricle, a collapsible rubber tube was placed in the inflow port of the centrifugal pump in series with the apex of the simulated ventricle. Experimentally, the centrifugal pump speed (rpm) was gradually increased to simulate the suction effect. The pump flow through the centrifugal pump measured by an electromagnetic flowmeter, the aortic pressure, and the motor current were continuously digitized at 100 Hz and stored in a personal computer. The analysis of the cross-spectral density between the pump flow and motor current waveforms revealed that 2 waveforms were highly correlated at the frequency range between 0 and 4 Hz, with the coherence and phase angles being close to 1.0 and 0 degree, respectively. The fast Fourier transform analysis of the motor current indicated that the second harmonic component of the motor current power density increased with the occurrence of the suction effect in the circuit. The ratio of the fundamental to the second harmonic component decreased less than 1.3 as the suction effect developed in the circuit. It is possible to detect and prevent the suction effect of the centrifugal blood pump in the natural ventricle through analysis of the motor current waveform.

  1. The slide centrifuge gram stain as a urine screening method.

    PubMed

    Olson, M L; Shanholtzer, C J; Willard, K E; Peterson, L R

    1991-10-01

    A slide centrifuge Gram stain procedure was performed to screen for bacteriuria 4161 urine specimens submitted in urine preservative tubes for routine culture. For slide centrifuge Gram staining, each urine sample was mixed well. Thereafter, 0.2 mL of each sample was placed, using a pipette, into a slide centrifuge chamber and centrifuged at 2,000 rpm for 5 minutes. The slides were heat fixed, Gram stained, and read by laboratory personnel who scanned 12 consecutive oil-immersion fields using a set pattern. The presence of the same organism in six or more fields was defined as a positive urine screen. Urine samples were cultured using a 0.001-mL loop and a comparison of culture growth with slide centrifuge screening was made. When growth of 100,000 or more colony-forming units per milliliter (CFU/mL) was the reference for comparison, the screen had a sensitivity rate of 98%, a specificity rate of 90%, a negative predictive value of 99%, and a positive predictive value of 65%. When a lower colony count of 10,000 or more CFU/mL was the reference for comparison, the screen had a sensitivity rate of 88%, a specificity rate of 95%, a negative predictive value of 96%, and a positive predictive value of 84%. The slide centrifuge Gram stain is a very sensitive screening method to detect bacteriuria in an adult male population.

  2. Centrifugal Compressor Aeroelastic Analysis Code

    NASA Astrophysics Data System (ADS)

    Keith, Theo G., Jr.; Srivastava, Rakesh

    2002-01-01

    Centrifugal compressors are very widely used in the turbomachine industry where low mass flow rates are required. Gas turbine engines for tanks, rotorcraft and small jets rely extensively on centrifugal compressors for rugged and compact design. These compressors experience problems related with unsteadiness of flowfields, such as stall flutter, separation at the trailing edge over diffuser guide vanes, tip vortex unsteadiness, etc., leading to rotating stall and surge. Considerable interest exists in small gas turbine engine manufacturers to understand and eventually eliminate the problems related to centrifugal compressors. The geometric complexity of centrifugal compressor blades and the twisting of the blade passages makes the linear methods inapplicable. Advanced computational fluid dynamics (CFD) methods are needed for accurate unsteady aerodynamic and aeroelastic analysis of centrifugal compressors. Most of the current day industrial turbomachines and small aircraft engines are designed with a centrifugal compressor. With such a large customer base and NASA Glenn Research Center being, the lead center for turbomachines, it is important that adequate emphasis be placed on this area as well. Currently, this activity is not supported under any project at NASA Glenn.

  3. Experimental and Theoretical Study on Circular Disk Particles Suspended in Centrifugal and Non-Centrifugal Force Environments

    SciTech Connect

    Torii, Shuichi; Watanabe, Yoshimi; Tanaka, Satoyuki; Yano, Toshiaki; Iino, Naoko

    2008-02-15

    Theoretical and experimental studies are performed on suspension particle motion in Centrifugal and Non-Centrifugal Force Environment, i.e., in both an axially rotating drum and a stable liquid tank. The particle velocity of circular disks is measured by PTV (Particle Tracking Velocimetry) method and is predicted by BBO (Basset-Boussinesq-Ossen) equation. It is found that (1) as time progresses, one side of the disk in the axially rotating drum is attracted toward the drum wall and its velocity is affected by the rotating speed, (2) when the particle moves in the Stokes' regime, its velocity is linearly increased with the distance from the center of the drum, (3) in contrast, the autorotation of the disk occurs in the non-centrifugal force field, and (4) the corresponding drag coefficient in the low Reynolds number region is in good agreement with the theoretical value of the sphere.

  4. Realization of Low Power High-Speed Channel Filters with Stringent Adjacent Channel Attenuation Specifications for Wireless Communication Receivers

    NASA Astrophysics Data System (ADS)

    Mathew, Jimson; Mahesh, R.; Vinod, A. P.; Lai, Edmund M.-K.

    Finite impulse response (FIR) filtering is the most computationally intensive operation in the channelizer of a wireless communication receiver. Higher order FIR channel filters are needed in the channelizer to meet the stringent adjacent channel attenuation specifications of wireless communications standards. The computational cost of FIR filters is dominated by the complexity of the coefficient multipliers. Even though many methods for reducing the complexity of filter multipliers have been proposed in literature, these works focused on lower order filters. This paper presents a coefficient-partitioning-based binary subexpression elimination method for realizing low power FIR filters. We show that the FIR filters implemented using proposed method consume less power and achieve speed improvement compared to existing filter implementations. Design examples of the channel filters employed in the Digital Advanced Mobile Phone System (D-AMPS) and Personal Digital Cellular (PDC) receivers show that the proposed method achieved 23% average reductions of full adder and power consumption and 23.3% reduction of delay over the best existing method. Synthesis results show that the proposed method offers average area reduction of 8% and power reduction of 22% over the best known method in literature.

  5. The impact of the centrifuge characteristics and centrifugation protocols on the cells, growth factors, and fibrin architecture of a leukocyte- and platelet-rich fibrin (L-PRF) clot and membrane.

    PubMed

    Dohan Ehrenfest, David M; Pinto, Nelson R; Pereda, Andrea; Jiménez, Paula; Corso, Marco Del; Kang, Byung-Soo; Nally, Mauricio; Lanata, Nicole; Wang, Hom-Lay; Quirynen, Marc

    2017-04-24

    of the visible cell bodies appeared destroyed (squashed or shrunk). In the second part of this study, the slow release of the three tested growth factors from original L-PRF membranes was significantly stronger (more than twice stronger, p<0.001) at all experimental times than the release from A-PRF membranes. No trace of BMP2 could be detected in the A-PRF. A slow release of BMP2 was detected during at least 7 days in the original L-PRF. Moreover, the original L-PRF clots and membranes (produced with 9 mL blood) were always significantly larger than the A-PRF (produced with 10 mL blood). The A-PRF membranes dissolved in vitro after less than 3 days, while the L-PRF membrane remained in good shape during at least 7 days. Each centrifuge has its clear own profile of vibrations depending on the rotational speed, and the centrifuge characteristics are directly impacting the architecture and cell content of a L-PRF clot. This result may reveal a considerable flaw in all the PRP/PRF literature, as this parameter was never considered. The original L-PRF clot (Intra-Spin) presented very specific characteristics, which appeared distorted when using centrifuges with a higher vibration level. A-PRF, LW and Salvin centrifuges produced PRF-like materials with a damaged and almost destroyed cell population through the standard protocol, and it is therefore impossible to classify these products in the L-PRF family. Moreover, when using the same centrifuge, the original L-PRF protocol allowed producing larger clots/membranes and a more intense release of growth factors (biological signature at least twice stronger) than the modified A-PRF protocol. Both protocols are therefore significantly different, and the clinical and experimental results from the original L-PRF shall not be extrapolated to the A-PRF. Finally, the comparison between the total released amounts and the initial content of the membrane (after forcible extraction) highlighted that the leukocytes living in the fibrin

  6. Rules governing the classification of coal slurries for filtering centrifuges

    SciTech Connect

    G.Y. Gol'berg; Y.B. Rubinshtein; S.A. Osadchii

    2008-07-01

    The feasibility of using filtering centrifuges for the cleaning of a coking-coal slurry is confirmed in principle, and regime operating parameters which ensure the production of a concentrate of conditioned quality are determined on the basis of results of experimental-industrial tests of a new procedure for this operation at the Neryungrinskaya Concentrating Mill. An equation is proposed for determination of solid carry-off in the centrifuge effluent, which completely satisfactorily (with a correlation coefficient of 0.7-0.8) describes the dependence of the parameter in question on the solid content in the centrifuge feed, and on its content of -0.2-mm material. It is noted that special investigations to determine the effect of the speed of the rotor and shape of the particles on the amount of solid carry-off in the centrifuge effluent are required for construction of a model describing the size reduction of solid-phase particles in the effluent during centrifuge filtration.

  7. High efficiency centrifugal pump

    SciTech Connect

    Nasvytis, P.J.; Jahrstorfer, G.W.

    1983-10-11

    A high speed fuel pump for a gas turnbine engine has a positively-driven shroud positioned between a main impeller and the wall of a pumping cavity to reduce impeller drag. The shroud is formed by a first disc having a boost impeller connected to its central hub portion and a second disc having a gear carried by its central hub portion. The main drive shaft assembly to which the main impeller is connected, carries a gear which meshes with gear mounted upon a shaft. The shaft also carries a gear which meshes with the gear. The gears are sized so that the shroud is driven at one-half the speed of the main impeller in order to maximize impeller drag reduction and enhance pumping capability when severe inlet conditions are present at the pump inlet.

  8. Gait-specific metabolic costs and preferred speeds in ring-tailed lemurs (Lemur catta), with implications for the scaling of locomotor costs.

    PubMed

    O'Neill, Matthew C

    2012-11-01

    Metabolic costs of resting and locomotion have been used to gain novel insights into the behavioral ecology and evolution of a wide range of primates; however, most previous studies have not considered gait-specific effects. Here, metabolic costs of ring-tailed lemurs (Lemur catta) walking, cantering and galloping are used to test for gait-specific effects and a potential correspondence between costs and preferred speeds. Metabolic costs, including the net cost of locomotion (COL) and net cost of transport (COT), change as a curvilinear function of walking speed and (at least provisionally) as a linear function of cantering and galloping speeds. The baseline quantity used to calculate net costs had a significant effect on the magnitude of speed-specific estimates of COL and COT, especially for walking. This is because non-locomotor metabolism constitutes a substantial fraction (41-61%, on average) of gross metabolic rate at slow speeds. The slope-based estimate of the COT was 5.26 J kg(-1) m(-1) for all gaits and speeds, while the gait-specific estimates differed between walking (0.5 m s(-1) : 6.69 J kg(-1) m(-1) ) and cantering/galloping (2.0 m s(-1) : 5.61 J kg(-1) m(-1) ). During laboratory-based overground locomotion, ring-tailed lemurs preferred to walk at ~0.5 m s(-1) and canter/gallop at ~2.0 m s(-1) , with the preferred walking speed corresponding well to the COT minima. Compared with birds and other mammals, ring-tailed lemurs are relatively economical in walking, cantering, and galloping. These results support the view that energetic optima are an important movement criterion for locomotion in ring-tailed lemurs, and other terrestrial animals.

  9. Splitter-bladed centrifugal compressor impeller designed for automotive gas turbine application. [at the Lewis Research Center

    NASA Technical Reports Server (NTRS)

    Pampreen, R. C.

    1977-01-01

    Mechanical design and fabrication of two splitter-bladed centrifugal compressor impellers were completed for rig testing at NASA Lewis Research Center. These impellers were designed for automotive gas turbine application. The mechanical design was based on NASA specifications for blade-shape and flowpath configurations. The contractor made engineering drawings and performed calculations for mass and center-of-gravity, for stress and vibration analyses, and for shaft critical speed analysis. One impeller was machined to print; the other had a blade height and exit radius of 2.54 mm larger than print dimensions.

  10. Modeling on Fluid Flow and Inclusion Motion in Centrifugal Continuous Casting Strands

    NASA Astrophysics Data System (ADS)

    Wang, Qiangqiang; Zhang, Lifeng; Sridhar, Seetharaman

    2016-08-01

    During the centrifugal continuous casting process, unreasonable casting parameters can cause violent level fluctuation, serious gas entrainment, and formation of frozen shell pieces at the meniscus. Thus, in the current study, a three-dimensional multiphase turbulent model was established to study the transport phenomena during centrifugal continuous casting process. The effects of nozzle position, casting and rotational speed on the flow pattern, centrifugal force acting on the molten steel, level fluctuation, gas entrainment, shear stress on mold wall, and motion of inclusions during centrifugal continuous casting process were investigated. Volume of Fluid model was used to simulate the molten steel-air two-phase. The level fluctuation and the gas entrainment during casting were calculated by user-developed subroutines. The trajectory of inclusions in the rotating system was calculated using the Lagrangian approach. The results show that during centrifugal continuous casting, a large amount of gas was entrained into the molten steel, and broken into bubbles of various sizes. The greater the distance to the mold wall, the smaller the centrifugal force. Rotation speed had the most important influence on the centrifugal force distribution at the side region. Angular moving angle of the nozzle with 8° and keeping the rotation speed with 60 revolutions per minute can somehow stabilize the level fluctuation. The increase of angular angle of nozzle from 8 to 18 deg and rotation speed from 40 to 80 revolutions per minute favored to decrease the total volume of entrained bubbles, while the increase of distance of nozzle moving left and casting speed had reverse effects. The trajectories of inclusions in the mold were irregular, and then rotated along the strand length. After penetrating a certain distance, the inclusions gradually moved to the center of billet and gathered there. More work, such as the heat transfer, the solidification, and the inclusions entrapment

  11. Factors affecting yield and survival of cells when suspensions are subjected to centrifugation. Influence of centrifugal acceleration, time of centrifugation, and length of the suspension column in quasi-homogeneous centrifugal fields.

    PubMed

    Katkov, I I; Mazur, P

    1999-01-01

    The goals of the centrifugation of cell suspensions are to obtain the maximum yield of cells with minimum adverse effects of centrifugation. In the case of mechanically sensitive cells such as mouse sperm, the two goals are somewhat contradictory in that g-forces sufficient to achieve high yields are damaging, and g-forces that yield high viability produce low yields. This paper mathematically analyzes the factors contributing to each goal. The total yield of pelleted cells is determined by the sedimentation rate governed by Stokes' Law, and depends on the relative centrifugal force, centrifugation time, size and shape of the cells, density of the cells and medium, viscosity of the medium, and the length of the column of suspension. Because in the situation analyzed the column is short relative to the rotor radius, the analysis considers the centrifugal field to be quasi-homogeneous. The assumption is that cells are not damaged during sedimentation, but that they become injured at an exponential rate once they are pelleted, a rate that will depend on the specific cell type. The behavior is modeled by the solution of coupled differential equations. The predictions of the analysis are in good agreement with experimental data on the centrifugation of mouse sperm.

  12. CENTRIFUGAL MEMBRANE FILTRATION

    SciTech Connect

    William A. Greene; Patricia A. Kirk; Richard Hayes; Joshua Riley

    2005-10-28

    SpinTek Membrane Systems, Inc., the developer of a centrifugal membrane filtration technology, has engineered and developed a system for use within the U.S. Department of Energy (DOE) Environmental Management (EM) Program. The technology uses supported microporous membranes rotating at high rpm, under pressure, to separate suspended and colloidal solids from liquid streams, yielding a solids-free permeate stream and a highly concentrated solids stream. This is a crosscutting technology that falls under the Efficient Separations and Processing Crosscutting Program, with potential application to tank wastes, contaminated groundwater, landfill leachate, and secondary liquid waste streams from other remediation processes, including decontamination and decommissioning systems. SpinTek II High Shear Rotary Membrane Filtration System is a unique compact crossflow membrane system that has large, demonstrable advantages in performance and cost compared to currently available systems: (1) High fluid shear prevents membrane fouling even with very high solids content; hazardous and radioactive components can be concentrated to the consistency of a pasty slurry without fouling. (2) Induced turbulence and shear across the membrane increases membrane flux by a factor of ten over existing systems and allows operation on fluids not otherwise treatable. (3) Innovative ceramic membrane and mechanical sealing technology eliminates compatibility problems with aggressive DOE waste streams. (4) System design allows rapid, simple disassembly for inspection or complete decontamination. (5) Produces colloidal- and suspended-solids-free filtrate without the addition of chemicals. The first phase of this project (PRDA maturity stage 5) completed the physical scale-up of the SpinTek unit and verified successful scale-up with surrogate materials. Given successful scale-up and DOE concurrence, the second phase of this project (PRDA maturity stage 6) will provide for the installation and

  13. Characterization of instability initiation in centrifugal compressors

    NASA Astrophysics Data System (ADS)

    Oakes, William Charles

    On a compressor performance map, the region of unstable operation is bounded by the surge line. As operation in this unstable region can be detrimental to the integrity of the machine, a surge margin is maintained. The proximity of the surge line to the compressor maximum pressure rise makes a reduction in the required surge margin desirable. Prior to establishing a strategy for designing a compressor with reduced surge margin, an understanding of the instability initiation process must be attained. The determination of the role that rotating stall plays in surge initiation of high speed compressors is of particular interest. Toward this end, a series of experiments at both low and high speed were undertaken to characterize centrifugal compressor rotating stall. Utilizing spatial arrays of inlet microphones and impeller mounted microphones, the origin of the low speed compressor rotating stall is found to be a separation zone near the impeller midchord that propagates at the stall frequency. This disturbance grows as the compressor is destabilized. The impeller flowfield during rotating stall has also been measured using PIV. The inducer region shows no separation at midspan. A region of zero relative velocity is located during the stall cycle at 70% impeller meridional chord. The investigation of the high-speed centrifugal compressor has identified two distinct rotating stall modes, a one mode and a nine mode. Both are located at or near the diffuser. Examination of the component performance reveals that the one mode is associated with mild or deep surge cycles while the nine mode exists independently and serves as a blockage, reducing diffuser performance. Rotating stall is observed between surge cycles, similar to axial compressor results. A surge chamber diffuser is employed and produces a 1% increase in maximum stable pressure coefficient. The surge chamber reduces the magnitude of the rotating stall by 60%. Speed transients at constant throttle settings are

  14. Lack of sex-specific movement patterns in an alien species at its invasion front - consequences for invasion speed.

    PubMed

    Herfindal, Ivar; Melis, Claudia; Åhlén, Per-Arne; Dahl, Fredrik

    2016-08-01

    Efficient targeting of actions to reduce the spread of invasive alien species relies on understanding the spatial, temporal, and individual variation of movement, in particular related to dispersal. Such patterns may differ between individuals at the invasion front compared to individuals in established and dense populations due to differences in environmental and ecological conditions such as abundance of conspecifics or sex-specific dispersal affecting the encounter rate of potential mates. We assessed seasonal and diurnal variation in movement pattern (step length and turning angle) of adult male and female raccoon dog at their invasion front in northern Sweden using data from Global Positioning System (GPS)-marked adult individuals and assessed whether male and female raccoon dog differed in their movement behavior. There were few consistent sex differences in movement. The rate of dispersal was rather similar over the months, suggesting that both male and female raccoon dog disperse during most of the year, but with higher speed during spring and summer. There were diurnal movement patterns in both sexes with more directional and faster movement during the dark hours. However, the short summer nights may limit such movement patterns, and long-distance displacement was best explained by fine-scale movement patterns from 18:00 to 05:00, rather than by movement patterns only from twilight and night. Simulation of dispersing raccoon dogs suggested a higher frequency of male-female encounters that were further away from the source population for the empirical data compared to a scenario with sex differences in movement pattern. The lack of sex differences in movement pattern at the invasion front results in an increased likelihood for reproductive events far from the source population. Animals outside the source population should be considered potential reproducing individuals, and a high effort to capture such individuals is needed throughout the year to prevent

  15. Analysis of cantilever NEMS in centrifugal-fluidic systems

    NASA Astrophysics Data System (ADS)

    Mohsen-Nia, Mohsen; Abadian, Fateme; Abadian, Naeime; Dehkordi, Keivan Mosaiebi; Keivani, Maryam; Abadyan, Mohamadreza

    2016-07-01

    Electromechanical nanocantilevers are promising for using as sensors/detectors in centrifugal-fluidic systems. For this application, the presence of angular speed and electrolyte environment should be considered in the theoretical analysis. Herein, the pull-in instability of the nanocantilever incorporating the effects of angular velocity and liquid media is investigated using a size-dependent continuum theory. Using d’Alembert principle, the angular speed is transformed into an equivalent centrifugal force. The electrochemical and dispersion forces are incorporated considering the corrections due to the presence of electrolyte media. Two different approaches, i.e., the Rayleigh-Ritz method (RRM) and proposing a lumped parameter model (LPM), were applied to analyze the system. The models are validated with the results presented in literature. Impacts of the angular velocity, electrolyte media, dispersion forces, and size effect on the instability characteristics of the nanocantilever are discussed.

  16. Perceived radial translation during centrifugation.

    PubMed

    Bos, Jelte E; Correia Grácio, Bruno J

    2015-01-01

    Linear acceleration generally gives rise to translation perception. Centripetal acceleration during centrifugation, however, has never been reported giving rise to a radial, inward translation perception. To study whether centrifugation can induce a radial translation perception in the absence of visual cues. To that end, we exposed 12 subjects to a centripetal acceleration with eyes closed. To avoid confounding with angular motion perception, subjects were fist rotated on-axis, and were shifted out fast and slow only after rotation sensation had vanished. They were asked for translation direction and velocity right after the shift-out, as well as after about 60 seconds of constant centrifugation. Independent of fast or slow shift-out, the vast statistically significant majority of trials yielded an inward radial translation perception, which velocity was constant after 60 seconds of constant centrifugation. We therefore conclude that during centrifugation, an inward radial translation perception does exist in humans, which perception reaches a constant, non-zero value during constant rotation, lasting for at least one minute. These results can be understood by high-pass filtering of otolith afferents to make a distinction between inertial and gravitational acceleration, followed by a mere integration over time to reach a constant velocity perception.

  17. Centrifuge-Based Fluidic Platforms

    NASA Astrophysics Data System (ADS)

    Zoval, Jim; Jia, Guangyao; Kido, Horacio; Kim, Jitae; Kim, Nahui; Madou, Marc

    In this chapter centrifuge-based microfluidic platforms are reviewed and compared with other popular microfluidic propulsion methods. The underlying physical principles of centrifugal pumping in microfluidic systems are presented and the various centrifuge fluidic functions such as valving, decanting, calibration, mixing, metering, heating, sample splitting, and separation are introduced. Those fluidic functions have been combined with analytical measurements techniques such as optical imaging, absorbance and fluorescence spectroscopy and mass spectrometry to make the centrifugal platform a powerful solution for medical and clinical diagnostics and high-throughput screening (HTS) in drug discovery. Applications of a compact disc (CD)-based centrifuge platform analyzed in this review include: two-point calibration of an optode-based ion sensor, an automated immunoassay platform, multiple parallel screening assays and cellular-based assays. The use of modified commercial CD drives for high-resolution optical imaging is discussed as well. From a broader perspective, we compare the technical barriers involved in applying microfluidics for sensing and diagnostic as opposed to applying such techniques to HTS. The latter poses less challenges and explains why HTS products based on a CD fluidic platform are already commercially available, while we might have to wait longer to see commercial CD-based diagnostics.

  18. Hemolysis in different centrifugal pumps.

    PubMed

    Kawahito, K; Nosé, Y

    1997-04-01

    Different types of centrifugal pumps cause different amounts of hemolysis based on shear stress and blood exposure time. However, the hemolytic characteristics of centrifugal pumps in each clinical condition are not always clear. We compared the hemolytic characteristics of one cone-type centrifugal pump (Medtronic BioMedicus BP-80) and 2 impeller-type centrifugal pumps (Nikkiso HMS-12 and Terumo Capiox) under experimental conditions simulating their use in cardiopulmonary bypass (CPB), extracorporeal membrane oxygenation (ECMO), and percutaneous cardiopulmonary support (PCPS) as well as their use as left ventricular assist devices (LVADs). The normalized indexes of hemolysis (NIHs; grams free plasma hemoglobin per 100 L blood pumped) during use as LVADs were not significantly different among the 3 pumps. The BP-80 pump produced almost 3-fold more hemolysis than the HMS-12 and Capiox pumps during CPB, 3- to 4-fold more hemolysis during ECMO, and 5.5-fold more hemolysis during PCPS. The 2 impeller-type centrifugal pumps will therefore cause less hemolysis under high flow, high pressure difference (as in CPB) and low flow, high pressure difference (as in ECMO and PCPS) conditions than the cone-type pump.

  19. Centrifugal governor for internal combustion engines

    SciTech Connect

    Ohnishi, M.

    1986-09-23

    A centrifugal governor is described for use with an internal combustion engine which consists of: a control rack for regulating the quantity of fuel to be supplied to the engine; flyweights radially displaceable in response to the rotational speed of the engine; a tension lever pivotable through an angle dependent upon the amount of radial displacement of the flyweights; an idling spring for urging the tension lever against radially outward displacement of the flyweights; a torque cam having a cam surface determining a fuel increment to be applied at the start of the engine; a sensor lever having one end engaged by the control rack, and another end adapted to engage with the cam surface of the torque cam; a cancelling spring interposed between the torque cam and the tension lever; a control lever; a floating lever interlocking with the control lever; and spring force adjusting means arranged at one end of the idling spring.

  20. Centrifugal slip casting of components

    SciTech Connect

    Steinlage, G.A.; Roeder, R.K.; Trumble, K.P.; Bowman, K.J.

    1996-05-01

    Research in layered and functionally gradient materials has emerged because of the increasing demand for high-performance engineering materials. Many techniques have been used to produce layered and functionally gradient components. Common examples include thermal spray processing, powder processing, chemical and physical vapor deposition, high-temperature or combustion synthesis, diffusion treatments, microwave processing and infiltration. Of these techniques, powder processing routes offer excellent microstructural control and product quality, and they are capable of producing large components. Centrifugal slip casting is a powder-processing technique combining the effects of slip casting and centrifugation. In slip casting, consolidation takes place as fluid is removed by the porous mold. Particles within the slip move with the suspending fluid until reaching the mold wall, at which point they are consolidated. In centrifugation, particles within the slip move through the fluid at a rate dependent upon the gravitational force and particle drag.

  1. Excessive centrifugal fields damage high density lipoprotein[S

    PubMed Central

    Munroe, William H.; Phillips, Martin L.; Schumaker, Verne N.

    2015-01-01

    HDL is typically isolated ultracentrifugally at 40,000 rpm or greater, however, such high centrifugal forces are responsible for altering the recovered HDL particle. We demonstrate that this damage to HDL begins at approximately 30,000 rpm and the magnitude of loss increases in a rotor speed-dependent manner. The HDL is affected by elevated ultracentrifugal fields resulting in a lower particle density due to the shedding of associated proteins. To circumvent the alteration of the recovered HDL, we utilize a KBr-containing density gradient and a lowered rotor speed of 15,000 rpm to separate the lipoproteins using a single 96 h centrifugation step. This recovers the HDL at two density ranges; the bulk of the material has a density of about 1.115 g/ml, while lessor amounts of material are recovered at >1.2 g/ml. Thus, demonstrating the isolation of intact HDL is possible utilizing lower centrifuge rotor speeds. PMID:25910941

  2. Bubble Eliminator Based on Centrifugal Flow

    NASA Technical Reports Server (NTRS)

    Gonda, Steve R.; Tsao, Yow-Min D.; Lee, Wenshan

    2004-01-01

    The fluid bubble eliminator (FBE) is a device that removes gas bubbles from a flowing liquid. The FBE contains no moving parts and does not require any power input beyond that needed to pump the liquid. In the FBE, the buoyant force for separating the gas from the liquid is provided by a radial pressure gradient associated with a centrifugal flow of the liquid and any entrained bubbles. A device based on a similar principle is described in Centrifugal Adsorption Cartridge System (MSC- 22863), which appears on page 48 of this issue. The FBE was originally intended for use in filtering bubbles out of a liquid flowing relatively slowly in a bioreactor system in microgravity. Versions that operate in normal Earth gravitation at greater flow speeds may also be feasible. The FBE (see figure) is constructed as a cartridge that includes two concentric cylinders with flanges at the ends. The outer cylinder is an impermeable housing; the inner cylinder comprises a gas-permeable, liquid-impermeable membrane covering a perforated inner tube. Multiple spiral disks that collectively constitute a spiral ramp are mounted in the space between the inner and outer cylinders. The liquid enters the FBE through an end flange, flows in the annular space between the cylinders, and leaves through the opposite end flange. The spiral disks channel the liquid into a spiral flow, the circumferential component of which gives rise to the desired centrifugal effect. The resulting radial pressure gradient forces the bubbles radially inward; that is, toward the inner cylinder. At the inner cylinder, the gas-permeable, liquid-impermeable membrane allows the bubbles to enter the perforated inner tube while keeping the liquid in the space between the inner and outer cylinders. The gas thus collected can be vented via an endflange connection to the inner tube. The centripetal acceleration (and thus the radial pressure gradient) is approximately proportional to the square of the flow speed and

  3. MEANS FOR DETERMINING CENTRIFUGE ALIGNMENT

    DOEpatents

    Smith, W.Q.

    1958-08-26

    An apparatus is presented for remotely determining the alignment of a centrifuge. The centrifage shaft is provided with a shoulder, upon which two followers ride, one for detecting radial movements, and one upon the shoulder face for determining the axial motion. The followers are attached to separate liquid filled bellows, and a tube connects each bellows to its respective indicating gage at a remote location. Vibrations produced by misalignment of the centrifuge shaft are transmitted to the bellows, and tbence through the tubing to the indicator gage. This apparatus is particularly useful for operation in a hot cell where the materials handled are dangerous to the operating personnel.

  4. Size-isolation of ultrasound-mediated phase change perfluorocarbon droplets using differential centrifugation.

    PubMed

    Mercado, Karla P; Radhakrishnan, Kirthi; Stewart, Kyle; Snider, Lindsay; Ryan, Devin; Haworth, Kevin J

    2016-05-01

    Perfluorocarbon droplets that are capable of an ultrasound-mediated phase transition have applications in diagnostic and therapeutic ultrasound. Techniques to modify the droplet size distribution are of interest because of the size-dependent acoustic response of the droplets. Differential centrifugation has been used to isolate specific sizes of microbubbles. In this work, differential centrifugation was employed to isolate droplets with diameters between 1 and 3 μm and 2 and 5 μm from an initially polydisperse distribution. Further, an empirical model was developed for predicting the droplet size distribution following differential centrifugation and to facilitate the selection of centrifugation parameters for obtaining desired size distributions.

  5. Lightweight, high speed bearing balls: A concept

    NASA Technical Reports Server (NTRS)

    Parker, R. J.

    1974-01-01

    Low mass bearing balls with hardened iron-plated surfaces can eliminate problems of low fatigue strength and flexure fatigue, and lead to increased life and reliability of high speed ball bearings. Low mass balls exert lower centrifugal forces on outer race of bearing thus eliminating detrimental effect of high speed operation.

  6. Validation of Temporal and Spatial Consistency of Facility- and Speed-specific VSP Distribution for Emission Estimation: A Case Study in Beijing.

    PubMed

    Zhai, Zhiqiang; Song, Guohua; Lu, Hongyu; He, Weinan; Yu, Lei

    2017-02-22

    Vehicle specific power (VSP) has been found to be highly correlated with vehicle emissions. It is used in many studies on emissions modeling such as the MOVES model. The existing studies develop specific VSP distributions (or OpMode distribution in MOVES) for different road types and various average speeds to represent the vehicle operating modes on road. However, it is still not clear if the facility- and speed-specific VSP distributions are consistent temporally and spatially. For instance, is it necessary to update periodically the database of the VSP distributions in the emission model? Are the VSP distributions developed in the city CBD area applicable to its suburb area? In this context, this study examined the temporal and spatial consistency of the facility- and speed-specific VSP distributions in Beijing. The VSP distributions in different years and in different areas are developed, based on real-world vehicle activity data. The root mean square error (RMSE) is employed to quantify the difference between the VSP distributions. The maximum differences of the VSP distributions between different years and between different areas are approximately 20% of that between different road types. The analysis on the CO2 emission factor indicates that the temporal and spatial differences of the VSP distributions have no significant impact on vehicle emission estimation, with relative error of less than 3%. Implications The temporal and spatial differences have no significant impact on the development of the facility- and speed-specific VSP distributions for the vehicle emission estimation. The database of the specific VSP distributions in the VSP-based emission models can maintain in terms of time. Thus it is unnecessary to update the database regularly, and it is reliable to use the history vehicle activity data to forecast the emissions in the future. In one city, the areas with less data can still develop accurate VSP distributions based on better data from other

  7. Centrifugal pumps for rocket engines

    NASA Technical Reports Server (NTRS)

    Campbell, W. E.; Farquhar, J.

    1974-01-01

    The use of centrifugal pumps for rocket engines is described in terms of general requirements of operational and planned systems. Hydrodynamic and mechanical design considerations and techniques and test procedures are summarized. Some of the pump development experiences, in terms of both problems and solutions, are highlighted.

  8. Life Sciences Centrifuge Facility assessment

    NASA Technical Reports Server (NTRS)

    Benson, Robert H.

    1994-01-01

    This report provides an assessment of the status of the Centrifuge Facility being developed by ARC for flight on the International Space Station Alpha. The assessment includes technical status, schedules, budgets, project management, performance of facility relative to science requirements, and identifies risks and issues that need to be considered in future development activities.

  9. Laser and gas centrifuge enrichment

    SciTech Connect

    Heinonen, Olli

    2014-05-09

    Principles of uranium isotope enrichment using various laser and gas centrifuge techniques are briefly discussed. Examples on production of high enriched uranium are given. Concerns regarding the possibility of using low end technologies to produce weapons grade uranium are explained. Based on current assessments commercial enrichment services are able to cover the global needs of enriched uranium in the foreseeable future.

  10. Life Sciences Centrifuge Facility review

    NASA Technical Reports Server (NTRS)

    Young, Laurence R.

    1994-01-01

    The Centrifuge Facility Project at ARC was reviewed by a code U team to determine appropriateness adequacy for the ISSA. This report represents the findings of one consultant to this team and concentrates on scientific and technical risks. This report supports continuation of the project to the next phase of development.

  11. Laser and gas centrifuge enrichment

    NASA Astrophysics Data System (ADS)

    Heinonen, Olli

    2014-05-01

    Principles of uranium isotope enrichment using various laser and gas centrifuge techniques are briefly discussed. Examples on production of high enriched uranium are given. Concerns regarding the possibility of using low end technologies to produce weapons grade uranium are explained. Based on current assessments commercial enrichment services are able to cover the global needs of enriched uranium in the foreseeable future.

  12. 77 FR 9273 - USEC Inc. (American Centrifuge Lead Cascade Facility and American Centrifuge Plant); Direct...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-16

    ... COMMISSION USEC Inc. (American Centrifuge Lead Cascade Facility and American Centrifuge Plant); Direct Transfer of Licenses In the Matter of USEC INC. (American Centrifuge Lead Cascade Facility and American... holder of materials licenses SNM-7003 and SNM-2011 for the American Centrifuge Lead Cascade Facility...

  13. An alternative arrangement of metered dosing fluid using centrifugal pump

    NASA Astrophysics Data System (ADS)

    Islam, Md. Arafat; Ehsan, Md.

    2017-06-01

    Positive displacement dosing pumps are extensively used in various types of process industries. They are widely used for metering small flow rates of a dosing fluid into a main flow. High head and low controllable flow rates make these pumps suitable for industrial flow metering applications. However their pulsating flow is not very suitable for proper mixing of fluids and they are relatively more expensive to buy and maintain. Considering such problems, alternative techniques to control the fluid flow from a low cost centrifugal pump is practiced. These include - throttling, variable speed drive, impeller geometry control and bypass control. Variable speed drive and impeller geometry control are comparatively costly and the flow control by throttling is not an energy efficient process. In this study an arrangement of metered dosing flow was developed using a typical low cost centrifugal pump using bypass flow technique. Using bypass flow control technique a wide range of metered dosing flows under a range of heads were attained using fixed pump geometry and drive speed. The bulk flow returning from the system into the main tank ensures better mixing which may eliminate the need of separate agitators. Comparative performance study was made between the bypass flow control arrangement of centrifugal pump and a diaphragm type dosing pump. Similar heads and flow rates were attainable using the bypass control system compared to the diaphragm dosing pump, but using relatively more energy. Geometrical optimization of the centrifugal pump impeller was further carried out to make the bypass flow arrangement more energy efficient. Although both the systems run at low overall efficiencies but the capital cost could be reduced by about 87% compared to the dosing pump. The savings in capital investment and lower maintenance cost very significantly exceeds the relatively higher energy cost of the bypass system. This technique can be used as a cost effective solution for

  14. Sandia National Laboratories 8. 8 metre (29-foot) and 10. 7-metre (35-foot) centrifuge facilities

    SciTech Connect

    Adams, P.H.; Ault, R.L.; Fulton, D.L.

    1980-05-01

    This report outlines the capabilities and limitations of the two centrifuges and gives other details which must be considered in preparing test specifications and designing fixtures, gives the theory and terminology of centrifuge testing, and describes the layout, operating principles, support functions, and reference material for each facility.

  15. Quasi-steady centrifuge method for unsaturated hydraulic properties

    USGS Publications Warehouse

    Caputo, M.C.; Nimmo, J.R.

    2005-01-01

    [1] We have developed the quasi-steady centrifuge (QSC) method as a variation of the steady state centrifuge method that can be implemented simply and inexpensively with greater versatility in terms of sample size and other features. It achieves these advantages by somewhat relaxing the criterion for steadiness of flow through the sample. This compromise entails an increase in measurement uncertainty but to a degree that is tolerable in most applications. We have tested this new approach with an easily constructed apparatus to establish a quasi-steady flow of water in unsaturated porous rock samples spinning in a centrifuge, obtaining measurements of unsaturated hydraulic conductivity and water retention that agree with results of other methods. The QSC method is adaptable to essentially any centrifuge suitable for hydrogeologic applications, over a wide range of sizes and operating speeds. The simplified apparatus and greater adaptability of this method expands the potential for exploring situations that are common in nature but have been the subject of few laboratory investigations. Copyright 2005 by the American Geophysical Union.

  16. 21 CFR 864.5350 - Microsedimentation centrifuge.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Microsedimentation centrifuge. 864.5350 Section 864.5350 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... § 864.5350 Microsedimentation centrifuge. (a) Identification. A microsedimentation centrifuge is a...

  17. 21 CFR 864.5350 - Microsedimentation centrifuge.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Microsedimentation centrifuge. 864.5350 Section 864.5350 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... § 864.5350 Microsedimentation centrifuge. (a) Identification. A microsedimentation centrifuge is a...

  18. 21 CFR 864.5350 - Microsedimentation centrifuge.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Microsedimentation centrifuge. 864.5350 Section 864.5350 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... § 864.5350 Microsedimentation centrifuge. (a) Identification. A microsedimentation centrifuge is a...

  19. 21 CFR 864.5350 - Microsedimentation centrifuge.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Microsedimentation centrifuge. 864.5350 Section 864.5350 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... § 864.5350 Microsedimentation centrifuge. (a) Identification. A microsedimentation centrifuge is a...

  20. High efficiency, variable geometry, centrifugal cryogenic pump

    SciTech Connect

    Forsha, M.D.; Nichols, K.E.; Beale, C.A.

    1994-12-31

    A centrifugal cryogenic pump has been developed which has a basic design that is rugged and reliable with variable speed and variable geometry features that achieve high pump efficiency over a wide range of head-flow conditions. The pump uses a sealless design and rolling element bearings to achieve high reliability and the ruggedness to withstand liquid-vapor slugging. The pump can meet a wide range of variable head, off-design flow requirements and maintain design point efficiency by adjusting the pump speed. The pump also has features that allow the impeller and diffuser blade heights to be adjusted. The adjustable height blades were intended to enhance the pump efficiency when it is operating at constant head, off-design flow rates. For small pumps, the adjustable height blades are not recommended. For larger pumps, they could provide off-design efficiency improvements. This pump was developed for supercritical helium service, but the design is well suited to any cryogenic application where high efficiency is required over a wide range of head-flow conditions.

  1. Application of Individualized Speed Thresholds to Interpret Position Specific Running Demands in Elite Professional Rugby Union: A GPS Study

    PubMed Central

    Reardon, Cillian; Tobin, Daniel P.; Delahunt, Eamonn

    2015-01-01

    A number of studies have used GPS technology to categorise rugby union locomotive demands. However, the utility of the results of these studies is confounded by small sample sizes, sub-elite player status and the global application of absolute speed thresholds to all player positions. Furthermore, many of these studies have used GPS units with low sampling frequencies. The aim of the present study was to compare and contrast the high speed running (HSR) demands of professional rugby union when utilizing micro-technology units sampling at 10 Hz and applying relative or individualised speed zones. The results of this study indicate that application of individualised speed zones results in a significant shift in the interpretation of the HSR demands of both forwards and backs and positional sub-categories therein. When considering the use of an absolute in comparison to an individualised HSR threshold, there was a significant underestimation for forwards of HSR distance (HSRD) (absolute = 269 ± 172.02, individualised = 354.72 ± 99.22, p < 0.001), HSR% (absolute = 5.15 ± 3.18, individualised = 7.06 ± 2.48, p < 0.001) and HSR efforts (HSRE) (absolute = 18.81 ± 12.25; individualised = 24.78 ± 8.30, p < 0.001). In contrast, there was a significant overestimation of the same HSR metrics for backs with the use of an absolute threshold (HSRD absolute = 697.79 ± 198.11, individualised = 570.02 ± 171.14, p < 0.001; HSR% absolute = 10.85 ± 2.82, individualised = 8.95 ± 2.76, p < 0.001; HSRE absolute = 41.55 ± 11.25; individualised = 34.54 ± 9.24, p < 0.001). This under- or overestimation associated with an absolute speed zone applies to varying degrees across the ten positional sub-categories analyzed and also to individuals within the same positional sub-category. The results of the present study indicated that although use of an individulised HSR threshold improves the interpretation of the HSR demands on a positional basis, inter-individual variability in maximum

  2. CENTRIFUGAL CASTING MACHINE

    DOEpatents

    Shuck, A.B.

    1958-04-01

    A device is described that is specifically designed to cast uraniumn fuel rods in a vacuunn, in order to obtain flawless, nonoxidized castings which subsequently require a maximum of machining or wastage of the expensive processed material. A chamber surrounded with heating elements is connected to the molds, and the entire apparatus is housed in an airtight container. A charge of uranium is placed in the chamber, heated, then is allowed to flow into the molds While being rotated. Water circulating through passages in the molds chills the casting to form a fine grained fuel rod in nearly finished form.

  3. Centrifugal separator devices, systems and related methods

    DOEpatents

    Meikrantz, David H [Idaho Falls, ID; Law, Jack D [Pocatello, ID; Garn, Troy G [Idaho Falls, ID; Todd, Terry A [Aberdeen, ID; Macaluso, Lawrence L [Carson City, NV

    2012-03-20

    Centrifugal separator devices, systems and related methods are described. More particularly, fluid transfer connections for a centrifugal separator system having support assemblies with a movable member coupled to a connection tube and coupled to a fixed member, such that the movable member is constrained to movement along a fixed path relative to the fixed member are described. Also, centrifugal separator systems including such fluid transfer connections are described. Additionally, methods of installing, removing and/or replacing centrifugal separators from centrifugal separator systems are described.

  4. Validation Test Report for NFLUX PRE: Validation of Specific Humidity, Surface Air Temperature, and Wind Speed Precision and Accuracy for Assimilation into Global and Regional Models

    DTIC Science & Technology

    2013-12-17

    NRL/MR/7320--14-9523 Validation Test Report for NFLUX PRE: Validation of Specific Humidity, Surface Air Temperature, and Wind Speed...REPORT DATE 17 DEC 2013 2. REPORT TYPE 3. DATES COVERED 00-00-2013 to 00-00-2013 4. TITLE AND SUBTITLE Validation Test Report for NFLUX PRE...products overlay the existing global product estimate. The location of the observations is tested to see if it falls within one of the regional areas

  5. High Efficiency Centrifugal Compressor for Rotorcraft Applications

    NASA Technical Reports Server (NTRS)

    Medic, Gorazd; Sharma, Om P.; Jongwook, Joo; Hardin, Larry W.; McCormick, Duane C.; Cousins, William T.; Lurie, Elizabeth A.; Shabbir, Aamir; Holley, Brian M.; Van Slooten, Paul R.

    2014-01-01

    The report "High Efficiency Centrifugal Compressor for Rotorcraft Applications" documents the work conducted at UTRC under the NRA Contract NNC08CB03C, with cost share 2/3 NASA, and 1/3 UTRC, that has been extended to 4.5 years. The purpose of this effort was to identify key technical barriers to advancing the state-of-the-art of small centrifugal compressor stages; to delineate the measurements required to provide insight into the flow physics of the technical barriers; to design, fabricate, install, and test a state-of-the-art research compressor that is representative of the rear stage of an axial-centrifugal aero-engine; and to acquire detailed aerodynamic performance and research quality data to clarify flow physics and to establish detailed data sets for future application. The design activity centered on meeting the goal set outlined in the NASA solicitation-the design target was to increase efficiency at higher work factor, while also reducing the maximum diameter of the stage. To fit within the existing Small Engine Components Test Facility at NASA Glenn Research Center (GRC) and to facilitate component re-use, certain key design parameters were fixed by UTRC, including impeller tip diameter, impeller rotational speed, and impeller inlet hub and shroud radii. This report describes the design effort of the High Efficiency Centrifugal Compressor stage (HECC) and delineation of measurements, fabrication of the compressor, and the initial tests that were performed. A new High-Efficiency Centrifugal Compressor stage with a very challenging reduction in radius ratio was successfully designed, fabricated and installed at GRC. The testing was successful, with no mechanical problems and the running clearances were achieved without impeller rubs. Overall, measured pressure ratio of 4.68, work factor of 0.81, and at design exit corrected flow rate of 3 lbm/s met the target requirements. Polytropic efficiency of 85.5 percent and stall margin of 7.5 percent were

  6. Centrifugal loop-mediated isothermal amplification microdevice for rapid, multiplex and colorimetric foodborne pathogen detection.

    PubMed

    Oh, Seung Jun; Park, Byung Hyun; Jung, Jae Hwan; Choi, Goro; Lee, Doh C; Kim, Do Hyun; Seo, Tae Seok

    2016-01-15

    We present a centrifugal microfluidic device which enables multiplex foodborne pathogen identification by loop-mediated isothermal amplification (LAMP) and colorimetric detection using Eriochrome Black T (EBT). Five identical structures were designed in the centrifugal microfluidic system to perform the genetic analysis of 25 pathogen samples in a high-throughput manner. The sequential loading and aliquoting of the LAMP cocktail, the primer mixtures, and the DNA sample solutions were accomplished by the optimized zigzag-shaped microchannels and RPM control. We targeted three kinds of pathogenic bacteria (Escherichia coli O157:H7, Salmonella typhimurium and Vibrio parahaemolyticus) and detected the amplicons of the LAMP reaction by the EBT-mediated colorimetric method. For the limit-of-detection (LOD) test, we carried out the LAMP reaction on a chip with serially diluted DNA templates of E. coli O157:H7, and could observe the color change with 380 copies. The used primer sets in the LAMP reaction were specific only to the genomic DNA of E. coli O157:H7, enabling the on-chip selective, sensitive, and high-throughput pathogen identification with the naked eyes. The entire process was completed in 60min. Since the proposed microsystem does not require any bulky and expensive instrumentation for end-point detection, our microdevice would be adequate for point-of-care (POC) testing with high simplicity and high speed, providing an advanced genetic analysis microsystem for foodborne pathogen detection.

  7. Theory and experiments on centrifuge cratering

    NASA Astrophysics Data System (ADS)

    Schmidt, R. M.; Holsapple, K. A.

    1980-01-01

    Centrifuge experimental techniques provide possibilities for laboratory simulation of ground motion and cratering effects due to explosive loadings. The results of a similarity analysis for the thermomechanical response of a continuum show that increased gravity is a necessary condition for subscale testing when identical materials for both model and prototype are being used. The general similarity requirements for this type of subscale testing are examined both theoretically and experimentally. The similarity analysis is used to derive the necessary and sufficient requirements due to the general balance and jump equations and gives relations among all the scale factors for size, density, stress, body forces, internal energy, heat supply, heat conduction, heat of detonation, and time. Additional constraints due to specific choices of material constitutive equations are evaluated separately. The class of constitutive equations that add no further requirements is identified. For this class of materials, direct simulation of large-scale cratering events at small scale on the centrifuge is possible and independent of the actual constitutive equations. For a rate-independent soil it is shown that a small experiment at gravity g and energy E is similar to a large event at 1 G but with energy equal to g3E. Consequently, experiments at 500 G with 8 grams of explosives can be used to simulate a kiloton in the field. A series of centrifuge experiments was performed to validate the derived similarity requirements and to determine the practicality of applying the technique to dry granular soils having little or no cohesion. Ten shots using Ottawa sand at various gravities confirmed reproducibility of results in the centrifuge environment, provided information on particle size effects, and demonstrated the applicability of the derived similitude requirements. These experiments used 0.5-4 grams of pentaerythritol-tetranitrate (PETN) and 1.7 grams of lead-azide explosives. They

  8. Investigation of Bond Strength in Centrifugal Lining of Babbitt on Cast Iron

    NASA Astrophysics Data System (ADS)

    Diouf, Papa; Jones, Alan

    2010-03-01

    The quality of the bond between Babbitt metal and a cast iron substrate was evaluated for centrifugal casting and static casting using the Chalmers bond strength method and scanning electron microscopy (SEM). The effect of three different centrifugal casting parameters, the speed of revolution, the pouring rate, and the cooling rate, was investigated. The bond strength and the microstructure at the bond interface were predominantly affected by the cooling rate, with a fast cooling rate resulting in better properties. The speed of revolution and the pouring rate only had a small effect on the bond strength, with faster revolution and faster pouring rate resulting in slightly better bonds.

  9. Echocardiographic outflow pump ramp test in centrifugal-flow left ventricular assist device.

    PubMed

    Iacovoni, Attilio; Vittori, Claudia; Fontana, Alessandra; Carobbio, Alessandra; Fino, Carlo; D'Elia, Emilia; Terzi, Amedeo; Senni, Michele

    2017-04-18

    This study sought to develop a novel echocardiogram outflow ramp test to detect device malfunctions in centrifugal-flow left ventricular assist devices (LVADs). This new ramp pump test is based on the direct analyses of systolic and diastolic ratio (S/D) Doppler velocity in the outflow cannula in the HeartWare LVAD during progressive increases in speed. The results showed that in patients with normal pump function, the Doppler velocity S/D ratio gradually decreased during LVAD speed increases. This test is easily performed and seems promising to detect normal pump function in patients assisted by a centrifugal flow LVAD.

  10. Dynamic considerations in the development of centrifugal separators used for reprocessing nuclear fuel

    SciTech Connect

    Strunk, W.D.; Singh, S.P.; Tuft, R.M.

    1988-01-01

    The development of centrifugal separators has been a key ingredient in improving the process used for reprocessing of spent nuclear fuel. The separators are used to segregate uranium and plutonium from the fission products produced by a controlled nuclear reaction. The separators are small variable speed centrifuges, designed to operate in a harsh environment. Dynamic problems were detected by vibration analysis and resolved using modal analysis and trending. Problems with critical speeds, resonances in the base, balancing, weak components, precision manufacturing, and short life have been solved.

  11. Impact testing with a centrifuge

    NASA Astrophysics Data System (ADS)

    Foglietta, Jim; Olin, Malcolm; Venturi, Richard

    A test program intended to verify an aircraft wing armor protection system is described, focusing on testing methodologies, the centrifuge release system design, and aiming and system controls. Two armor impact tests were conducted which used a centrifuge to propel a large irregular projectile into a target surface. The first test was performed on the armor protected side of the simulated fuel tank. The impactor was deflected off the armored surface, damaging the armor slightly and causing a small leak in the tank. The impactor broke into three pieces. The second test was performed on the reverse side of the simulated fuel tank. The impactor penetrated the tank and remained lodged inside, causing a massive leak.

  12. Performance of a centrifugal phytotron

    NASA Astrophysics Data System (ADS)

    Tani, A.; Nishiura, Y.; Kiyota, M.; Murase, H.; Honami, N.; Aiga, I.

    1996-01-01

    It is possible to cultivate plants under an artificial gravity field generated by a centrifugal device in space. In order to determine an optimal magnitude of gravity, there is a need to investigate the relationship between plant growth and gravity, including not only reduced gravity but also gravity greater than 1G. A prototype centrifugal phytotron was designed and fabricated in order to investigate the relationship between plant growth and increased gravity. This device enables us to cultivate plants over the long term by controlling environmental conditions in the phytotron such as temperature, relative humidity, CO_2 concentration and light intensity. The results of our experiment indicate that plant seeds can germinate and grow even under an artificial gravity which changes sinusoidally from 2G to 4G.

  13. Waves in a gas centrifuge

    NASA Astrophysics Data System (ADS)

    Bogovalov, S. V.; Kislov, V. A.; Tronin, I. V.

    2016-09-01

    Impact of the pulsed braking force on the axial gas circulation and gas content in centrifuges for uranium isotope separation was investigated by the method of numerical simulation. Pulsed brake of the rotating gas by the momentum source results into generation of the waves which propagate along the rotor of the centrifuge. The waves almost doubles the axial circulation flux in the working camera in compare with the case of the steady state breaking force with the same average power in the model under the consideration. Flux through the hole in the bottom baffle on 15% exceeds the flux in the stationary case for the same pressure and temperature in the model. We argue that the waves reduce the pressure in the GC on the same 15%.

  14. When to maintain centrifugal pumps

    SciTech Connect

    Karassik, I.J.

    1993-04-01

    Centrifugal pumps comprise critical maintenance equipment. The rationale of when to maintain them relates to a spreading tendency to contain costs in the face of tight money. Plant managers are thus entitled to a thorough analysis of whether reduced expenditures truly lower costs or actually hinder maintenance and increase costs. Absence of such an analysis hides the fact that proper and timely maintenance has a double effect: it not only reduces power consumption but also extends equipment life, and thus reduces the frequency of labor and material expenditures for scheduled or crisis maintenance. Centrifugal pump maintenance can demonstrate well the validity of this observation. The paper discusses: restoring internal clearances; real cost of renewing clearances; and monitoring clearances and pump performance.

  15. On sound generation mechanism by a centrifugal blower

    NASA Astrophysics Data System (ADS)

    Wu, Sean

    2002-05-01

    Centrifugal blower noise has often been modeled as dipoles and quadrupoles to account for the effects of fluid-structure interaction and turbulence as the impeller rotates. However, many experimental results have shown that sound powers from centrifugal blowers increase with speed to the power of 4-6, which implies the existence of a monopole [Lighthill, Proc. R. Soc., Ser. A 222, 564-587 (1952)]. This paper demonstrates that such a monopole indeed exists for a blower running inside a heating ventilation and air-conditioning (HVAC) unit of a vehicle. Tests indicate that this monopole is producible by a volumetric fluctuation due to an unsteady rotor. When the blower is operated at the voltage power input specified by the car manufacturer, the sound power increases with the speed to the power of 4. When the blower is installed on a stable shaft and running at the same voltage power input, the volumetric fluctuations are significantly reduced and the sound power increases with speed to the power of 6. This implies that the monopole sound has been effectively replaced by the dipole sound. Since dipole is less effective in generating sound at low speeds than monopole, eliminating rotor fluctuations can lower vehicle HVAC noise levels.

  16. Speed(s).

    ERIC Educational Resources Information Center

    Levy-Leblond, Jean-Marc

    1980-01-01

    Presents three simple distinct operational procedures for transforming the empirical notion of speed into a formal concept. The relationship between these three procedures and Galilean velocity and Einsteinian relativity is also included. (HM)

  17. Specification of minimum short circuit capacity for three-phase unbalance evaluation of high-speed railway power system

    SciTech Connect

    Chen, S.L.; Kao, F.C.; Lee, T.M.

    1995-12-31

    In the paper, firstly, the authors present an efficient computational algorithm to evaluate the short circuit capacity distribution at a substation bus, and on basis of this distribution to specify the minimum short circuit capacity for the year under evaluation. Secondly, the authors estimate the maximum traction load at seven 161kv substations of Taiwan high-speed railway system which is now under planning. Thirdly, using the maximum traction load and the minimum short circuit capacity derived, the authors estimate the maximum unbalance of the 3{phi} voltage at these seven 161kv substations, and compare their results with that by Taipower to demonstrate the effectiveness of their proposed algorithm.

  18. Development of Advanced Centrifugal Pumps

    SciTech Connect

    Rohatgi, U.

    2009-09-30

    A CRADA project was performed between BNL and Flowserve, California, under the auspices of Initiative for Proliferation Prevention (IPP) with the DOE support. The purpose was to jointly support a team of Russian institutes led by Kurchatov Institute to develop technology to increase operating life of centrifugal pumps. The work was performed from March 1, 2002 to September 30, 2009. The project resulted in development and validation the total cost of the sub-contract with Kurchatov Institute was $700,000, with matching fund from the industrial partner, Flowserve. The technical objective of this project is to develop advanced centrifugal pumps for the power, petroleum, chemical and water services industries by increasing the reliability of pumping equipment without a corresponding increase in life cycle cost. This major market need can be served by developing centrifugal pumps that generate only modest forces on the mechanical system even when operating under significant off-design conditions. This project is focused towards understanding the origin of hydraulic forces (both radial and axial, steady and time-dependent) and to develop design options, which reduce these forces over a broad flow range. This focus will include the force generation due to cavitation inside the pump as the operating conditions extend to low suction pressures. The results of research will reduce the inception of cavitation that leads to surface erosion and to find passive method of reducing peaks in axial thrust during whole range of flow rates.

  19. Practical considerations in realizing a magnetic centrifugal mass filter

    SciTech Connect

    Gueroult, Renaud; Fisch, Nathaniel J.

    2012-12-15

    The magnetic centrifugal mass filter concept represents a variation on the plasma centrifuge, with applications that are particularly promising for high-throughput separation of ions with large mass differences. A number of considerations, however, constrain the parameter space in which this device operates best. The rotation speed, magnetic field intensity, and ion temperature are constrained by the ion confinement requirements. Collisions must also be large enough to eject ions, but small enough not to eject them too quickly. The existence of favorable regimes meeting these constraints is demonstrated by a single-particle orbit code. As an example of interest, it is shown that separation factors of about 2.3 are achievable in a single pass when separating Aluminum from Strontium ions.

  20. A centrifugal pump concept designed for multiple use in space

    NASA Astrophysics Data System (ADS)

    Wunderlich, E.; Wulz, H. G.

    A centrifugal pump concept was elaborated for a multiple application in future spacecrafts. Based on this concept a prototype of a small centrifugal pump was manufactured and comprehensively tested. The model pump has been approved in different test series with the fluids liquid ammonia and demineralized water. The design of the model pump was driven by strict requirements of COLUMBUS, namely long life, noiseless operation, minimum mass and low energy consumption. Because of its modular design and as a result of selected materials of multiple compatibility, this pump is suited for the delivery of various further fluids, such as freons, hydrocarbons, propellants (hydrazine) etc.. It is also capable of pumping corrosive or toxic fluids for laboratory processes in space. The wide speed range from about 1,00 to 20,000 rpm which corresponds to a flow from about 1 to 20 l/min, permits an energy saving adaption and flow control.

  1. Fabrication of silk fibroin film using centrifugal casting technique for corneal tissue engineering.

    PubMed

    Lee, Min Chae; Kim, Dong-Kyu; Lee, Ok Joo; Kim, Jung-Ho; Ju, Hyung Woo; Lee, Jung Min; Moon, Bo Mi; Park, Hyun Jung; Kim, Dong Wook; Kim, Su Hyeon; Park, Chan Hum

    2016-04-01

    Films prepared from silk fibroin have shown potential as biomaterials in tissue engineering applications for the eye. Here, we present a novel process for fabrication of silk fibroin films for corneal application. In this work, fabrication of silk fibroin films was simply achieved by centrifugal force. In contrast to the conventional dry casting method, we carried out the new process in a centrifuge with a rotating speed of 4000 rpm, where centrifugal force was imposed on an aluminum tube containing silk fibroin solution. In the present study, we also compared the surface roughness, mechanical properties, transparency, and cell proliferation between centrifugal and dry casting method. In terms of surface morphology, films fabricated by the centrifugal casting have less surface roughness than those by the dry casting. For elasticity and transparency, silk fibroin films obtained from the centrifugal casting had favorable results compared with those prepared by dry casting. Furthermore, primary human corneal keratocytes grew better in films prepared by the centrifugal casting. Therefore, our results suggest that this new fabrication process for silk fibroin films offers important potential benefits for corneal tissue regeneration.

  2. Magnetically Coupled Adjustable Speed Motor Drives - Motor Tip Sheet #13

    SciTech Connect

    2008-07-01

    Alternating current electric motors rotate at a nearly constant speed that is determined by motor design and line frequency. Energy savings of 50% or more may be available when fixed speed systems are modified to allow the motor speed to match variable load requirements of a centrifugal fan or pump.

  3. Concept designs of nonrotating-type centrifugal blood pump and basic study on output characteristics of the oscillating disk-type centrifugal pump.

    PubMed

    Kabei, N; Tuichiya, K; Sakurai, Y

    1994-09-01

    When designing a turbo-type blood pump as an artificial heart, the gap between a rotating shaft and a pump housing should be perfectly sealed to prevent any leakage or contamination through a seal. In addition, blood coagulation in a blood chamber must be avoided. To overcome these problems, we proposed five different nonrotating-type turbo pumps: a caudal-fin-type axial-flow pump, a caudal-fin-type centrifugal pump, a nutating-column-type centrifugal pump, a nutating-collapsible-tube-type centrifugal pump, and an oscillating-disk-type centrifugal pump. We selected and developed the oscillating-disk-type centrifugal pump that consists of a disk, a driving rod, a seal, an oscillation mechanism, and a pump housing. The disk is mounted on the end of the rod, which is connected to a high-speed DC motor through an oscillation mechanism. The rod and the disk do not rotate, but they oscillate in the pump housing. This movement of the disk generates forward fluid flow around the axis (i.e., the rotational fluid flow). Centrifugal force due to fluid rotation supports the pressure difference between the outlet and the inlet. The diameter of the disk is 39 mm, the maximum inner diameter of the pump housing is 40 mm, and the volume of the blood chamber for 25 degrees' oscillation is 16.9 ml. The performance of the pump was tested in a mock circulatory system.(ABSTRACT TRUNCATED AT 250 WORDS)

  4. Comparative hemolysis study of clinically available centrifugal pumps.

    PubMed

    Naito, K; Suenaga, E; Cao, Z L; Suda, H; Ueno, T; Natsuaki, M; Itoh, T

    1996-06-01

    Centrifugal pumps have become important devices for cardiopulmonary bypass and circulatory assistance. Five types of centrifugal pumps are clinically available in Japan. To evaluate the blood trauma caused by centrifugal pumps, a comparative hemolysis study was performed under identical conditions. In vitro hemolysis test circuits were constructed to operate the BioMedicus BP-80 (Medtronic, BioMedicus), Sarns Delphin (Sarns/3M Healthcare), Isoflow (St. Jude Medical [SJM]), HPM-15 (Nikkiso), and Capiox CX-SP45 (Terumo). The hemolysis test loop consisted of two 1.5 m lengths of polyvinyl chloride tubing with a 3/8-inch internal diameter, a reservoir with a sampling port, and a pump head. All pumps were set to flow at 6 L/min against the total pressure head of 120 mm Hg. Experiments were conducted simultaneously for 6 h at room temperature (21 degrees C) with fresh bovine blood. Blood samples for plasma-free hemoglobin testing were taken, and the change in temperature at the pump outlet port was measured during the experiment. The mean pump rotational speeds were 1,570, 1,374, 1,438, 1,944, and 1,296 rpm, and the normalized indexes of hemolysis were 0.00070, 0.00745, 0.00096, 0.00066, 0.00090 g/100 L for the BP-80, Sarns, SJM, Nikkiso, and Terumo pumps, respectively. The change in temperature at the pump outlet port was the least for the Nikkiso pump (1.8 degrees C) and the most with the SJM pump (3.8 degrees C). This study showed that there is no relationship between the pump rotational speed (rpm) and the normalized index of hemolysis in 5 types of centrifugal pumps. The pump design and number of impellers could be more notable factors in blood damage.

  5. Twinning of amphibian embryos by centrifugation

    NASA Technical Reports Server (NTRS)

    Black, S. D.

    1984-01-01

    In the frog Xenopus laevis, the dorsal structures of the embryonic body axis normally derive from the side of the egg opposite the side of sperm entry. However, if the uncleaved egg is inclined at lg or centrifuged in an inclined position, this topographic relationship is overridden: the egg makes its dorsal axial structures according to its orientation in the gravitational/centrifugal field, irrespective of the position of sperm entry. Certain conditions of centrifugation cause eggs to develop into conjoined twins with two sets of axial structures. A detailed analysis of twinning provided some insight into experimental axis orientation. First, as with single-axis embryos, both axes in twins are oriented according to the direction of centrifugation. One axis forms at the centripetal side of the egg and the other forms at the centrifugal side, even when the side of sperm entry is normal to the centrifugal force vector. Second, if eggs are centrifuged to give twins, but are inclined at lg to prevent post-centrifugation endoplasmic redistributions, only single-axis embryos develop. Thus, a second redistribution is required for high-frequency secondary axis formation. This can be accomplished by lg (as in the single centrifugations) or by a second centrifugation directed along the egg's animal-vegetal axis.

  6. Twinning of amphibian embryos by centrifugation

    NASA Technical Reports Server (NTRS)

    Black, S. D.

    1984-01-01

    In the frog Xenopus laevis, the dorsal structures of the embryonic body axis normally derive from the side of the egg opposite the side of sperm entry. However, if the uncleaved egg is inclined at lg or centrifuged in an inclined position, this topographic relationship is overridden: the egg makes its dorsal axial structures according to its orientation in the gravitational/centrifugal field, irrespective of the position of sperm entry. Certain conditions of centrifugation cause eggs to develop into conjoined twins with two sets of axial structures. A detailed analysis of twinning provided some insight into experimental axis orientation. First, as with single-axis embryos, both axes in twins are oriented according to the direction of centrifugation. One axis forms at the centripetal side of the egg and the other forms at the centrifugal side, even when the side of sperm entry is normal to the centrifugal force vector. Second, if eggs are centrifuged to give twins, but are inclined at lg to prevent post-centrifugation endoplasmic redistributions, only single-axis embryos develop. Thus, a second redistribution is required for high-frequency secondary axis formation. This can be accomplished by lg (as in the single centrifugations) or by a second centrifugation directed along the egg's animal-vegetal axis.

  7. Velocity thresholds for women's soccer matches: sex specificity dictates high-speed running and sprinting thresholds - Female Athletes in Motion (FAiM).

    PubMed

    Bradley, Paul S; Vescovi, Jason D

    2015-01-01

    There is no methodological standardization of velocity thresholds for the quantification of distances covered in various locomotor activities for women's soccer matches, especially for high-speed running and sprinting. Applying velocity thresholds used for motion analysis of men's soccer has likely created skewed observations about high-intensity movement demands for the women's game because these thresholds do not accurately reflect the capabilities of elite female players. Subsequently, a cohesive view of the locomotor characteristics of women's soccer does not yet exist. The aim of this commentary is to provide suggestions for standardizing high-speed running and sprint velocity thresholds specific to women's soccer. The authors also comment on using generic vs individualized thresholds, as well as age-related considerations, to establish velocity thresholds.

  8. Effects of centrifugal force and centrifugation time on the sedimentation of plant organelles.

    PubMed

    Nagahashi, J; Hiraike, K

    1982-02-01

    The effect of centrifugal force and length of centrifugation time on the sedimentation of plant organelles was determined for corn (Zea mays L.) root homogenates. A centrifugal force of 6000g for at least 20 minutes was necessary to pellet 90% of the mitochondrial marker (cytochrome c oxidase). This initial centrifugation step is optimal for separating mitochondria from microsomes, since cross-contamination of endoplasmic reticulum and plasma membrane vesicles with mitochondria is minimized. Centrifugal forces of 8000g or 10,000g for 20 minutes and 13,000g for 15 minutes pellet 90% of the mitochondrial marker; however, these centrifugation conditions also sediment more plasma membrane and endoplasmic reticulum.

  9. Use of the Centritech Lab centrifuge for perfusion culture of hybridoma cells in protein-free medium.

    PubMed

    Johnson, M; Lanthier, S; Massie, B; Lefebvre, G; Kamen, A A

    1996-01-01

    As part of an effort to develop a suspension-culture perfusion-based process with high flow rate without the fouling and antibody retention inherent to filter-based cell-separation devices, we have evaluated and contributed to the development of the Centritech Lab centrifuge for the perfusion culture of hybridoma cells in protein-free medium. Culture start-ups showed that cell growth and monoclonal-antibody (MAb) production rates were similar in both a spinner flask and continuous centrifugation coupled to a bioreactor. The centrifuge efficiently separated viable cells from dead ones. Viable-cell recoveries were never below 98%, whereas dead-cell recoveries were usually around 80%. The cell content of the centrifuge supernatant and concentrate was strongly determined by the total amount of cells, viable and dead, in the culture broth, but an influence of the centrifugation parameters (feed rate, times of separation and discharge, and rotor speed) was observed. This understanding of the separation process inside the centrifuge is important and may apply to other similar devices. Monoclonal antibodies were not retained in the bioreactor during centrifugation perfusion. However, whereas similar growth rates were obtained in perfusion cultures using either continuous centrifugation or filtration, MAb concentrations were 35% lower in the former case. Utilization of the centrifuge in an intermittent fashion decreased the daily cell residence time outside the bioreactor, the daily pelleted-cell residence time in the centrifuge, and the frequency of cell passage to the centrifuge. This led to higher viable-cell numbers in the bioreactor and an accompanying increase in MAb concentrations, 225-250 mg of IgM L-1, equal to the performance of filter-based perfusion systems with the same cell line. It was hypothesized that having cells periodically packed at the bottom of the centrifuge insert (up to 800 x 10(6) cells mL-1) is deleterious to the culture by exposing the pelleted

  10. Fluids vertical transfer utilizing VFD based centrifugal pumps

    NASA Astrophysics Data System (ADS)

    Thiruchelvam, Vinesh; Hong, Lim Min

    2017-04-01

    Efficiency of centrifugal pumps has been consistently improving with technology enhancements. Pump manufacturers have increased the variety of pump dimension. Pump selection is based on application selection primarily on energy conversation. In a conventional pumping system, the pump will be driven at the same speed even though the output usage is below the actual demand. As a result, energy is wasted and the pump could have been driven at a lower speed for the same operational function. One of the ideal solutions is to vary the pump speed based on real-time demand. The paper illustrates the system simulation for a high rise building water transfer and the relevant design calculations such as the volumetric flow rate and net positive suction head. Supporting this operational function, the variable frequency device (VFD) has also been designed and simulated by using the Proteus software.

  11. Ultrasound-Assisted Extraction, Centrifugation and Ultrafiltration: Multistage Process for Polyphenol Recovery from Purple Sweet Potatoes.

    PubMed

    Zhu, Zhenzhou; Jiang, Tian; He, Jingren; Barba, Francisco J; Cravotto, Giancarlo; Koubaa, Mohamed

    2016-11-20

    This work provides an evaluation of an ultrasound-assisted, combined extraction, centrifugation and ultrafiltration process for the optimal recovery of polyphenols. A purple sweet potato (PSP) extract has been obtained using ultrasonic circulating extraction equipment at a power of 840 W, a frequency of 59 kHz and using water as solvent. Extract ultrafiltration, using polyethersulfone (PES), was carried out for the recovery of polyphenol, protein and anthocyanin. Pre-treatment, via the centrifugation of purple sweet potato extract at 2500 rpm over 6 min, led to better polyphenol recovery, with satisfactory protein removal (reused for future purposes), than PSP extract filtration without centrifugation. Results showed that anthocyanin was efficiently recovered (99%) from permeate. The exponential model fit well with the experimental ultrafiltration data and led to the calculation of the membrane's fouling coefficient. The optimization of centrifugation conditions showed that, at a centrifugation speed of 4000 rpm (1195× g) and duration of 7.74 min, the optimized polyphenol recovery and fouling coefficient were 34.5% and 29.5 m(-1), respectively. The removal of proteins in the centrifugation process means that most of the anthocyanin content (90%) remained after filtration. No significant differences in the intensities of the HPLC-DAD-ESI-MS² peaks were found in the samples taken before and after centrifugation for the main anthocyanins; peonidin-3-feruloylsophoroside-5-glucoside, peonidin-3-caffeoyl-p-hydroxybenzoylsophoroside-5-glucoside, and peonidin-3-caffeoyl-feruloyl sophoroside-5-glucoside. This proves that centrifugation is an efficient method for protein removal without anthocyanin loss. This study considers this process an ultrasound-assisted extraction-centrifugation-ultrafiltration for purple sweet potato valorization in "green" technology.

  12. A modeling study of a centrifugal compressor

    SciTech Connect

    Popovic, P.; Shapiro, H.N.

    1998-12-31

    A centrifugal compressor, which is part of a chlorofluorocarbon R-114 chiller installation, was investigated, operating with a new refrigerant, hydrofluorocarbon R-236ea, a proposed alternative to R-114. A large set of R-236ea operating data, as well as a limited amount of R-114 data, were available for this study. A relatively simple analytical compressor model was developed to describe compressor performance. The model was built upon a thorough literature search, experimental data, and some compressor design parameters. Two original empirical relations were developed, providing a new approach to the compressor modeling. The model was developed in a format that would permit it to be easily incorporated into a complete chiller simulation. The model was found to improve somewhat on the quantitative and physical aspects of a compressor model of the same format found in the literature. It was found that the compressor model is specific to the particular refrigerant.

  13. Experimental and numerical investigation of unsteady behavior of cavitating vortices in draft tube of low specific speed Francis turbine

    NASA Astrophysics Data System (ADS)

    Tamura, Y.; Tani, K.; Okamoto, N.

    2014-03-01

    At both partial and full load of Francis turbines, the unsteady behavior of cavitating draft tube vortices occurs and leads to undesirable matters such as power house vibration, noise and power swing in some cases. This paper presents the investigation of the interaction between the flow pattern at runner outlet and the unsteady behavior of cavitating vortices in draft tube with experimental and numerical approaches. On the experimental research, the pressure pulsation in the draft tube is measured and the unsteady behavior of cavitating vortices is taken pictures with a high speed camera in the model test. On the numerical research, by Computational Fluid Dynamics (CFD) adopting a two-phase unsteady analysis, the analysis domain from the guide vane to the draft tube is carried out for investigating the interaction between the runner outlet flow and the vortex pattern. The pressure pulsation at the upper draft tube and the unsteady behavior of cavitating vortices obtained from CFD results are similar to those obtained in the model test. Detailed analysis of CFD results at overload indicates the repeat of expansion and contraction of cavitating vortices, which were shaped helical vortices with opposite direction of runner rotation, and the corresponding flow pattern in every time step of the pressure pulsations.

  14. Centrifugal separators and related devices and methods

    DOEpatents

    Meikrantz, David H [Idaho Falls, ID; Law, Jack D [Pocatello, ID; Garn, Troy G [Idaho Falls, ID; Macaluso, Lawrence L [Carson City, NV; Todd, Terry A [Aberdeen, ID

    2012-03-06

    Centrifugal separators and related methods and devices are described. More particularly, centrifugal separators comprising a first fluid supply fitting configured to deliver fluid into a longitudinal fluid passage of a rotor shaft and a second fluid supply fitting sized and configured to sealingly couple with the first fluid supply fitting are described. Also, centrifugal separator systems comprising a manifold having a drain fitting and a cleaning fluid supply fitting are described, wherein the manifold is coupled to a movable member of a support assembly. Additionally, methods of cleaning centrifugal separators are described.

  15. Pressure data from a 64A010 airfoil at transonic speeds in heavy gas media of ratio of specific heats from 1.67 to 1.12

    NASA Technical Reports Server (NTRS)

    Gross, A. R.; Steinle, F. W., Jr.

    1975-01-01

    A NACA 64A010 pressure-instrumented airfoil was tested at transonic speeds over a range of angle of attack from -1 to 12 degrees at various Reynolds numbers ranging from 2 to 6 million in air, argon, Freon 12, and a mixture of argon and Freon 12 having a ratio of specific heats corresponding to air. Good agreement of results is obtained for conditions where compressibility is not significant and for the air and comparable argon-Freon 12 mixture. Comparison of heavy gas results with air, when adjusted for transonic similarity, show improved, but less than desired agreement.

  16. Centrifugal acceleration in the isotropic photon field

    NASA Astrophysics Data System (ADS)

    Bakhtadze, G. G.; Berezhiani, V. I.; Osmanov, Z.

    In this paper, we study centrifugal acceleration of particles moving along a prescribed rotating curved trajectories. We consider the physical system embedded in an isotropic photon field and study the influence of the photon drag force on the acceleration process. For this purpose, we study three major configurations of the field lines: the straight line, the Archimede spiral and the dipolar field line configuration. By analyzing dynamics of particles sliding along the field lines in the equatorial plane, we have found several interesting features of motion. In particular, it has been shown that for rectilinear field lines, the particles reach the light cylinder (area where the linear velocity of rotation exactly equals the speed of light) zone relatively slowly for bigger drag forces. Considering the Archimedes’ spiral, we have found that in cases when the field lines lag behind the rotation, the particles achieve the force-free regime of dynamics regardless of the drag force. Unlike this scenario, when the spiral is oriented in an opposite direction, the particles do not reach the force free regime, but tend to stable equilibrium locations.

  17. Centrifugal governor for internal combustion engines

    SciTech Connect

    Ohkoshi, M.

    1987-04-14

    This patent describes a centrifugal governor for use with an internal combustion engine, comprising: a control rack for regulating the quantity of fuel to be supplied to the engine; flyweights radially displaceable in response to the rotational speed of the engine; a tension lever pivotable through an angle dependent upon the amount of radial displacement of the flyweights; a torque cam pivotable about and relative to a fulcrum shaft thereof and having a cam surface including a cam surface portion determining a fuel increment to be applied at the start of the engine; a sensor lever having one end engaged by the control rack; the sensor lever having another end disposed to engage with the cam surface portion of the torque cam when the engine is in a starting condition, to permit displacement of the control rack into a fuel increasing position for the start of the engine; and a cancelling spring interposed between the torque cam and the tension lever and urging the torque cam with a force dependent upon the angularity of the tension lever to cause pivoting of the torque cam about the fulcrum shaft thereof in a direction of disengaging the sensor lever from the cam surface portion of the torque cam. The improvement is described comprising biasing means for forcibly pivotally displacing, immediately before operation of a starter of the engine, the torque cam in one direction against the urging force of the cancelling spring to a predetermined position.

  18. Centrifugal governor for internal combustion engines

    SciTech Connect

    Ohnishi, M.

    1986-08-12

    A centrifugal governor is described for use with an internal combustion engine, comprising: a control rack for regulating the quantity of fuel to be supplied to the engine; flyweights radially displaceable in response to the rotational speed of the engine; a tension lever pivotable about a stationary fulcrum in response to the radial displacement of the flyweights; a torque cam having a cam surface determining a fuel increment to be applied at the start of the engine; a sensor lever having one end engaged by the control rack and another end disposed for engagement with the cam surface of the torque cam, the sensor lever being adapted to engage with the cam surface of the torque cam when the engine is in a starting condition, to cause displacement of the control rack into a fuel increasing position for the start of the engine; and spring means interposed between the torque cam and the tension lever and urging the torque cam with a force dependent upon the angularity of the tension lever in a direction of disengaging the sensor lever from the cam surface of the torque cam; the spring means comprising first and second springs, one of the first and second springs being formed of a thermosensitive material having a smaller spring constant at a low temperature below a predetermined value, and a larger spring constant at a temperature above the predetermined value; and the first and second springs of the spring means comprising coiled springs disposed concentrically with each other.

  19. Hydraulic forces on a centrifugal impeller undergoing synchronous whirl

    NASA Technical Reports Server (NTRS)

    Allaire, P. E.; Sato, C. J.; Branagan, L. A.

    1984-01-01

    High speed centrifugal rotating machinery with large vibrations caused by aerodynamic forces on impellers was examined. A method to calculate forces in a two dimensional orbiting impeller in an unbounded fluid with nonuniform entering flow was developed. A finite element model of the full impeller is employed to solve the inviscid flow equations. Five forces acting on the impeller are: Coriolis forces, centripetal forces, changes in linear momentum, changes in pressure due to rotation and pressure changes due to linear momentum. Both principal and cross coupled stiffness coefficients are calculated for the impeller.

  20. Tuning of shortening speed in coleoid cephalopod muscle: no evidence for tissue-specific muscle myosin heavy chain isoforms

    PubMed Central

    Shaffer, Justin F.; Kier, William M.

    2015-01-01

    The contractile protein myosin II is ubiquitous in muscle. It is widely accepted that animals express tissue-specific myosin isoforms that differ in amino acid sequence and ATPase activity in order to tune muscle contractile velocities. Recent studies, however, suggested that the squid Doryteuthis pealeii might be an exception; members of this species do not express muscle-specific myosin isoforms, but instead alter sarcomeric ultrastructure to adjust contractile velocities. We investigated whether this alternative mechanism of tuning muscle contractile velocity is found in other coleoid cephalopods. We analyzed myosin heavy chain transcript sequences and expression profiles from muscular tissues of a cuttlefish, Sepia officinalis, and an octopus, Octopus bimaculoides, in order to determine if these cephalopods express tissue-specific myosin heavy chain isoforms. We identified transcripts of four and six different myosin heavy chain isoforms in S. officinalis and O. bimaculoides muscular tissues, respectively. Transcripts of all isoforms were expressed in all muscular tissues studied, and thus S. officinalis and O. bimaculoides do not appear to express tissue-specific muscle myosin isoforms. We also examined the sarcomeric ultrastructure in the transverse muscle fibers of the arms of O. bimaculoides and the arms and tentacles of S. officinalis using transmission electron microscopy and found that the fast contracting fibers of the prey capture tentacles of S. officinalis have shorter thick filaments than those found in the slower transverse muscle fibers of the arms of both species. It thus appears that coleoid cephalopods, including the cuttlefish and octopus, may use ultrastructural modifications rather than tissue-specific myosin isoforms to adjust contractile velocities. PMID:26997860

  1. Tuning of shortening speed in coleoid cephalopod muscle: no evidence for tissue-specific muscle myosin heavy chain isoforms.

    PubMed

    Shaffer, Justin F; Kier, William M

    2016-03-01

    The contractile protein myosin II is ubiquitous in muscle. It is widely accepted that animals express tissue-specific myosin isoforms that differ in amino acid sequence and ATPase activity in order to tune muscle contractile velocities. Recent studies, however, suggested that the squid Doryteuthis pealeii might be an exception; members of this species do not express muscle-specific myosin isoforms, but instead alter sarcomeric ultrastructure to adjust contractile velocities. We investigated whether this alternative mechanism of tuning muscle contractile velocity is found in other coleoid cephalopods. We analyzed myosin heavy chain transcript sequences and expression profiles from muscular tissues of a cuttlefish, Sepia officinalis, and an octopus, Octopus bimaculoides, in order to determine if these cephalopods express tissue-specific myosin heavy chain isoforms. We identified transcripts of four and six different myosin heavy chain isoforms in S. officinalis and O. bimaculoides muscular tissues, respectively. Transcripts of all isoforms were expressed in all muscular tissues studied, and thus S. officinalis and O. bimaculoides do not appear to express tissue-specific muscle myosin isoforms. We also examined the sarcomeric ultrastructure in the transverse muscle fibers of the arms of O. bimaculoides and the arms and tentacles of S. officinalis using transmission electron microscopy and found that the fast contracting fibers of the prey capture tentacles of S. officinalis have shorter thick filaments than those found in the slower transverse muscle fibers of the arms of both species. It thus appears that coleoid cephalopods, including the cuttlefish and octopus, may use ultrastructural modifications rather than tissue-specific myosin isoforms to adjust contractile velocities.

  2. Modelling of horizontal centrifugal casting of work roll

    NASA Astrophysics Data System (ADS)

    Xu, Zhian; Song, Nannan; Tol, Rob Val; Luan, Yikun; Li, Dianzhong

    2012-07-01

    A numerical model to simulate horizontal centrifugal roll castings is presented in this paper. In order to simulate the flow fluid and solidification of horizontal centrifugal roll casting correctly, the model uses a body fitted mesh technique to represent the geometry. This new method maps a plate layer mesh to a circular mesh. The smooth body fitted mesh method gives more accurate calculation results for cylindrical geometries. A velocity depending on the angular velocity and inner radius of the mould is set up as a velocity boundary condition. The fluid flow coupled with heat transfer and solidification in a rapidly rotating roll is simulated. A gravity free falling method is applied as a pouring condition. A moveable pouring system is also used in the simulations. High speed steel is used to produce the work roll. Two different gating positions and a moveable gating system are simulated in this paper. Results show that the position of pouring system has a significant influence on the temperature distribution. The temperature distribution at a fixed central pouring system is more favourable than the distribution from a side pouring system. A moving gating system method is a better way to obtain a uniform temperature field in centrifugal casting and offers an alternative for existing techniques.

  3. Effect of centrifugal forces on dimensional error of bored shapes

    NASA Astrophysics Data System (ADS)

    Arsuaga, M.; de Lacalle, L. N. López; Lobato, R.; Urbikain, G.; Campa, F.

    2012-04-01

    Boring operations of deep holes with a slender boring bar are often hindered by the precision because of their low static stiffness and high deformations. Because of that, it is not possible to remove much larger depths of cuts than the nose radius of the tool, unlike the case of turning and face milling operations, and consequently, the relationship between the cutting force distribution, tool geometry, feed rate and depth of cut becomes non-linear and complex. This problem gets worse when working with a rotating boring head where apart from the cutting forces and the variation of the inclination angle because of shape boring, the bar and head are affected by de centrifugal forces. The centrifugal forces, and therefore the centrifugal deflection, will vary as a function of the rotating speed, boring bar mass distribution and variable radial position of the bar in shape boring. Taking in to account all this effects, a load and deformation model was created. This model has been experimentally validated to use as a corrector factor of the radial position of the U axis in the boring head.

  4. Multiphase flow modeling in centrifugal partition chromatography.

    PubMed

    Adelmann, S; Schwienheer, C; Schembecker, G

    2011-09-09

    The separation efficiency in Centrifugal Partition Chromatography (CPC) depends on selection of a suitable biphasic solvent system (distribution ratio, selectivity factor, sample solubility) and is influenced by hydrodynamics in the chambers. Especially the stationary phase retention, the interfacial area for mass transfer and the flow pattern (backmixing) are important parameters. Their relationship with physical properties, operating parameters and chamber geometry is not completely understood and predictions are hardly possible. Experimental flow visualization is expensive and two-dimensional only. Therefore we simulated the flow pattern using a volume-of-fluid (VOF) method, which was implemented in OpenFOAM®. For the three-dimensional simulation of a rotating FCPC®-chamber, gravitational centrifugal and Coriolis forces were added to the conservation equation. For experimental validation the flow pattern of different solvent systems was visualized with an optical measurement system. The amount of mobile phase in a chamber was calculated from gray scale values of videos recorded by an image processing routine in ImageJ®. To visualize the flow of the stationary phase polyethylene particles were used to perform a qualitative particle image velocimetry (PIV) analysis. We found a good agreement between flow patterns and velocity profiles of experiments and simulations. By using the model we found that increasing the chamber depth leads to higher specific interfacial area. Additionally a circular flow in the stationary phase was identified that lowers the interfacial area because it pushes the jet of mobile phase to the chamber wall. The Coriolis force alone gives the impulse for this behavior. As a result the model is easier to handle than experiments and allows 3D prediction of hydrodynamics in the chamber. Additionally it can be used for optimizing geometry and operating parameters for given physical properties of solvent systems. Copyright © 2011 Elsevier B

  5. Optimization of flavanones extraction by modulating differential solvent densities and centrifuge temperatures.

    PubMed

    Chebrolu, Kranthi K; Jayaprakasha, G K; Jifon, J; Patil, Bhimanagouda S

    2011-07-15

    Understanding the factors influencing flavonone extraction is critical for the knowledge in sample preparation. The present study was focused on the extraction parameters such as solvent, heat, centrifugal speed, centrifuge temperature, sample to solvent ratio, extraction cycles, sonication time, microwave time and their interactions on sample preparation. Flavanones were analyzed in a high performance liquid chromatography (HPLC) and later identified by liquid chromatography and mass spectrometry (LC-MS). The five flavanones were eluted by a binary mobile phase with 0.03% phosphoric acid and acetonitrile in 20 min and detected at 280 nm, and later identified by mass spectral analysis. Dimethylsulfoxide (DMSO) and dimethyl formamide (DMF) had optimum extraction levels of narirutin, naringin, neohesperidin, didymin and poncirin compared to methanol (MeOH), ethanol (EtOH) and acetonitrile (ACN). Centrifuge temperature had a significant effect on flavanone distribution in the extracts. The DMSO and DMF extracts had homogeneous distribution of flavanones compared to MeOH, EtOH and ACN after centrifugation. Furthermore, ACN showed clear phase separation due to differential densities in the extracts after centrifugation. The number of extraction cycles significantly increased the flavanone levels during extraction. Modulating the sample to solvent ratio increased naringin quantity in the extracts. Current research provides critical information on the role of centrifuge temperature, extraction solvent and their interactions on flavanone distribution in extracts. Published by Elsevier B.V.

  6. Analogue scale modelling of extensional tectonic processes using a large state-of-the-art centrifuge

    NASA Astrophysics Data System (ADS)

    Park, Heon-Joon; Lee, Changyeol

    2017-04-01

    Analogue scale modelling of extensional tectonic processes such as rifting and basin opening has been numerously conducted. Among the controlling factors, gravitational acceleration (g) on the scale models was regarded as a constant (Earth's gravity) in the most of the analogue model studies, and only a few model studies considered larger gravitational acceleration by using a centrifuge (an apparatus generating large centrifugal force by rotating the model at a high speed). Although analogue models using a centrifuge allow large scale-down and accelerated deformation that is derived by density differences such as salt diapir, the possible model size is mostly limited up to 10 cm. A state-of-the-art centrifuge installed at the KOCED Geotechnical Centrifuge Testing Center, Korea Advanced Institute of Science and Technology (KAIST) allows a large surface area of the scale-models up to 70 by 70 cm under the maximum capacity of 240 g-tons. Using the centrifuge, we will conduct analogue scale modelling of the extensional tectonic processes such as opening of the back-arc basin. Acknowledgement This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (grant number 2014R1A6A3A04056405).

  7. Thickening of ultrafine coal-water slurries in a solid-bowl centrifuge

    SciTech Connect

    Pinkerton, A.P.; Klima, M.S.; Morrison, J.L.; Miller, B.G.

    1999-07-01

    As part of a study being conducted for the Electric Power Research Institute's (EPRI's) Upgraded Coal Interest Group (UCIG) to evaluate ultrafine coal dewatering technologies, testing was carried out to investigate the use of a solid-bowl (high-g) centrifuge for thickening ultrafine coalwater slurries. The objective of this study was to increase the solids concentration to a level suitable for use as a coal-water slurry fuel, while maximizing overall solids recovery. Feed material was collected from the combined discharge (centrate) streams from several screen-bowl centrifuges. These devices are currently being used in a commercial coal cleaning facility to dewater the clean coal product from a froth flotation circuit. Current plant practice is to discharge the centrate to settling ponds. The screen bowl centrate averages 5% solids by weight and contains nearly 60% material finer than 10 {mu}m. The current study examined the effects of operating conditions on centrifuge performance. The test conditions included centrifuge bowl and scroll speeds and volumetric feed rate. In addition to thickening, some cleaning was also achieved, because the finest particles (e.g. < 3 {micro}m), which contained a large percentage of liberated clays, were removed with the bulk of the water. The centrifuge products were analyzed for solids concentration, particle size distribution, and ash content. Size selectivity curves were also used to evaluate centrifuge performance.

  8. Isolation of Intact Mitochondria from Skeletal Muscle by Differential Centrifugation for High-resolution Respirometry Measurements.

    PubMed

    Djafarzadeh, Siamak; Jakob, Stephan Mathias

    2017-03-08

    Mitochondria are involved in cellular energy metabolism and use oxygen to produce energy in the form of adenosine triphosphate (ATP). Differential centrifugation at low- and high-speed is commonly used to isolate mitochondria from tissues and cultured cells. Crude mitochondrial fractions obtained by differential centrifugation are used for respirometry measurements. The differential centrifugation technique is based on the separation of organelles according to their size and sedimentation velocity. The isolation of mitochondria is performed immediately after tissue harvesting. The tissue is immersed in an ice-cold homogenization medium, minced using scissors and homogenized in a glass homogenizer with a loose-fitting pestle. The differential centrifugation technique is efficient, fast and inexpensive and the mitochondria obtained by differential centrifugation are pure enough for respirometry assays. Some of the limitations and disadvantages of isolated mitochondria, based on differential centrifugation, are that the mitochondria can be damaged during the homogenization and isolation procedure and that large amounts of the tissue biopsy or cultured cells are required for the mitochondrial isolation.

  9. Laser tracker TSPI uncertainty quantification via centrifuge trajectory

    NASA Astrophysics Data System (ADS)

    Romero, Edward; Paez, Thomas; Brown, Timothy; Miller, Timothy

    2009-08-01

    Sandia National Laboratories currently utilizes two laser tracking systems to provide time-space-position-information (TSPI) and high speed digital imaging of test units under flight. These laser trackers have been in operation for decades under the premise of theoretical accuracies based on system design and operator estimates. Advances in optical imaging and atmospheric tracking technology have enabled opportunities to provide more precise six degree of freedom measurements from these trackers. Applying these technologies to the laser trackers requires quantified understanding of their current errors and uncertainty. It was well understood that an assortment of variables contributed to laser tracker uncertainty but the magnitude of these contributions was not quantified and documented. A series of experiments was performed at Sandia National Laboratories large centrifuge complex to quantify TSPI uncertainties of Sandia National Laboratories laser tracker III. The centrifuge was used to provide repeatable and economical test unit trajectories of a test-unit to use for TSPI comparison and uncertainty analysis. On a centrifuge, testunits undergo a known trajectory continuously with a known angular velocity. Each revolution may represent an independent test, which may be repeated many times over for magnitudes of data practical for statistical analysis. Previously these tests were performed at Sandia's rocket sled track facility but were found to be costly with challenges in the measurement ground truth TSPI. The centrifuge along with on-board measurement equipment was used to provide known ground truth position of test units. This paper discusses the experimental design and techniques used to arrive at measures of laser tracker error and uncertainty.

  10. Apparatus for centrifugal separation of coal particles

    SciTech Connect

    Dickie, William; Cavallaro, Joseph A.; Killmeyer, Richard P.

    1991-01-01

    A gravimetric cell for centrifugal separation of fine coal by density has a cylindrical body and a butterfly valve or other apparatus for selectively sealing the body radially across the approximate center of the cylinder. A removable top is provided which seals the cylinder in the centrifuge and in unvented areas.

  11. Isotopic enrichment in a plasma centrifuge

    SciTech Connect

    Del Bosco, E.; Dallaqua, R.S.; Ludwig, G.O.; Bittencourt, J.A.

    1987-06-15

    High rotational velocity and centrifugal isotopic separation of carbon in a vacuum-arc plasma centrifuge are presented. Enrichments of up to 390% for /sup 13/C are measured at 6 cm radius with angular rotation frequencies in excess of 1.0 x 10/sup 5/ rad/s in an axial magnetic field of 0.12 T.

  12. Novel high-speed droplet-allele specific-polymerase chain reaction: application in the rapid genotyping of single nucleotide polymorphisms.

    PubMed

    Taira, Chiaki; Matsuda, Kazuyuki; Yamaguchi, Akemi; Sueki, Akane; Koeda, Hiroshi; Takagi, Fumio; Kobayashi, Yukihiro; Sugano, Mitsutoshi; Honda, Takayuki

    2013-09-23

    Single nucleotide alterations such as single nucleotide polymorphisms (SNP) and single nucleotide mutations are associated with responses to drugs and predisposition to several diseases, and they contribute to the pathogenesis of malignancies. We developed a rapid genotyping assay based on the allele-specific polymerase chain reaction (AS-PCR) with our droplet-PCR machine (droplet-AS-PCR). Using 8 SNP loci, we evaluated the specificity and sensitivity of droplet-AS-PCR. Buccal cells were pretreated with proteinase K and subjected directly to the droplet-AS-PCR without DNA extraction. The genotypes determined using the droplet-AS-PCR were then compared with those obtained by direct sequencing. Specific PCR amplifications for the 8 SNP loci were detected, and the detection limit of the droplet-AS-PCR was found to be 0.1-5.0% by dilution experiments. Droplet-AS-PCR provided specific amplification when using buccal cells, and all the genotypes determined within 9 min were consistent with those obtained by direct sequencing. Our novel droplet-AS-PCR assay enabled high-speed amplification retaining specificity and sensitivity and provided ultra-rapid genotyping. Crude samples such as buccal cells were available for the droplet-AS-PCR assay, resulting in the reduction of the total analysis time. Droplet-AS-PCR may therefore be useful for genotyping or the detection of single nucleotide alterations. Copyright © 2013 Elsevier B.V. All rights reserved.

  13. Motion of a Probe Ball in the Fluid under Centrifugal Acceleration

    NASA Astrophysics Data System (ADS)

    Nyrkova, I. A.; Semenov, A. N.; Khokhlov, A. R.; Linliu, K.; Chu, B.

    1997-11-01

    The viscosity of a fluid can be measured by observing the motion of a probe sphere (or ball) in a centrifuge tube filled with this fluid. The hydrodynamic behavior of the probe ball moving in the centrifuge tube has been solved theoretically. We have got the universal relationship (for balls of a given material andsize in a given tube) between the terminal ball velocity, the fluid viscosity and the centrifuge acceleration using the only adjustable parameter — the rotational friction coefficient between the ball and the tube. The rotation of the centrifuge tube in the horizontal plane induces an inertia force which is counterbalanced by the friction force acting on the ball. As a result, the ball moves along the tube with some characteristic speed, which is a measure of the viscosity of the fluid. This speed was calculated in the lubrication approximation. The gravitational acceleration causes the ball to move very close to the bottom of the centrifuge tube. In this situation, the gravity is balanced by a “levitation” force introduced and calculated in the present paper. The origin of this force is the formation of the “bubble” behind and below the moving ball. The theoretical development on the terminal velocity for the ball moving very near the bottom of the horizontal centrifuge tube is tested by using a specially designed centrifuge for two types of balls and a wide set of viscosity standards. Excellent agreement between theory and experiment suggests that we have developed a new approach to measure high viscosities of fluids at low shear rates which might be especially useful for the investigation of polymer melts.

  14. Rotor for centrifugal fast analyzers

    DOEpatents

    Lee, N.E.

    1984-01-01

    The invention is an improved photometric analyzer of the rotary cuvette type, the analyzer incorporating a multicuvette rotor of novel design. The rotor (a) is leaktight, (b) permits operation in the 90/sup 0/ and 180/sup 0/ excitation modes, (c) is compatible with extensively used Centrifugal Fast Analyzers, and (d) can be used thousands of times. The rotor includes an assembly comprising a top plate, a bottom plate, and a central plate, the rim of the central plate being formed with circumferentially spaced indentations. A uv-transmitting ring is sealably affixed to the indented rim to define with the indentations an array of cuvettes. The ring serves both as a sealing means and an end window for the cuvettes.

  15. Rotor for centrifugal fast analyzers

    DOEpatents

    Lee, Norman E.

    1985-01-01

    The invention is an improved photometric analyzer of the rotary cuvette type, the analyzer incorporating a multicuvette rotor of novel design. The rotor (a) is leaktight, (b) permits operation in the 90.degree. and 180.degree. excitation modes, (c) is compatible with extensively used Centrifugal Fast Analyzers, and (d) can be used thousands of times. The rotor includes an assembly comprising a top plate, a bottom plate, and a central plate, the rim of the central plate being formed with circumferentially spaced indentations. A UV-transmitting ring is sealably affixed to the indented rim to define with the indentations an array of cuvettes. The ring serves both as a sealing means and an end window for the cuvettes.

  16. Centrifuges in gravitational physiology research

    NASA Technical Reports Server (NTRS)

    Ballard, Rodney W.; Davies, Phil; Fuller, Charles A.

    1993-01-01

    Data from space flight and ground based experiments have clearly demonstrated the importance of Earth gravity for normal physiological function in man and animals. Gravitational Physiology is concerned with the role and influence of gravity on physiological systems. Research in this field examines how we perceive and respond to gravity and the mechanisms underlying these responses. Inherent in our search for answers to these questions is the ability to alter gravity, which is not physically possible without leaving Earth. However, useful experimental paradigms have been to modify the perceived force of gravity by changing either the orientation of subjects to the gravity vector (i.e., postural changes) or by applying inertial forces to augment the magnitude of the gravity vector. The later technique has commonly been used by applying centripetal force via centrifugation.

  17. Centrifugal membrane filtration -- Task 9

    SciTech Connect

    1996-08-01

    The Energy and Environmental Research Center (EERC) has teamed with SpinTek Membrane Systems, Inc., the developer of a centrifugal membrane filtration technology, to demonstrate applications for the SpinTek technology within the US Department of Energy (DOE) Environmental management (EM) Program. The technology uses supported microporous membranes rotating at high rpm, under pressure, to separate suspended and colloidal solids from liquid streams, yielding a solids-free permeate stream and a highly concentrated solids stream. This is a crosscutting technology that falls under the Efficient Separations and Processing Crosscutting Program, with potential application to tank wastes, contaminated groundwater, landfill leachate, and secondary liquid waste streams from other remediation processes, including decontamination and decommissioning systems. Membrane-screening tests were performed with the SpinTek STC-X4 static test cell filtration unit, using five ceramic membranes with different pore size and composition. Based on permeate flux, a 0.25-{micro}m TiO{sub 2}/Al{sub 2}O{sub 3} membrane was selected for detailed performance evaluation using the SpinTek ST-IIL centrifugal membrane filtration unit with a surrogate tank waste solution. An extended test run of 100 hr performed on a surrogate tank waste solution showed some deterioration in filtration performance, based on flux, apparently due to the buildup of solids near the inner portion of the membrane where relative membrane velocities were low. Continued testing of the system will focus on modifications to the shear pattern across the entire membrane surface to affect improved long-term performance.

  18. Concrete Cleaning, Inc. centrifugal shot blaster: Baseline report; Summary

    SciTech Connect

    1997-07-31

    The centrifugal shot blaster is an electronically operated shot-blast machine that removes layer of concrete of varying depths. Hardened steel shot propelled at a high rate of speed abrades the surface of the concrete. The depth of material removed is determined by the rate of speed the machine is traveling and the volume of shot being fired into the blast chamber. The steel shot is reused until it is pulverized to dust, which is deposited in the waste container with the concrete being removed. Debris is continually vacuumed by a large dust collection system attached to the shot blaster. The safety and health evaluation during the human factors assessment focused on two main areas: noise and dust.

  19. Cavitation Performance of a Centrifugal Pump with Water and Mercury

    NASA Technical Reports Server (NTRS)

    Hammitt, F. G.; Barton, R. K.; Cramer, V. F.; Robinson, M. J.

    1961-01-01

    The cavitation performance of a given centrifugal pump with water (hot and cold) and mercury is compared. It is found that there are significant scale effects with all fluids tested, with the Thoma cavitation parameter decreasing in all cases for increased pump speed or fluid Reynolds' number. The data for a fixed flow coefficient fall into a single curve when plotted against pump speed (or fluid velocity), rather than against Reynolds' number. Conversely, the Thoma parameter for a given Reynolds' number is approximately twice as large for mercury as for water. The direction of this variation is as predicted from consideration of the cavitation thermodynamic parameters which vary by a factor of 10(exp 7) between these fluids. No difference in cavitation performance between hot and cold water (approximately 160 F and 80 F) was observed, However, the thermodynamic parameters vary only by a factor of 5.

  20. Performance of high pressure COIL with centrifugal bubble singlet oxygen generator

    NASA Astrophysics Data System (ADS)

    Zagidullin, Marsel V.; Nikolaev, Valery D.; Khvatov, Nikolay A.; Svistun, Michael I.

    2007-05-01

    A centrifugal bubbling SOG is a perspective source of oxygen at high pressure with high depletion of the BHP in the single burn dawn. The theoretical estimations show that at high centrifugal acceleration gas-liquid contact specific surface 30cm -1, frequency of the surface renewal can less than 10 -3s and bubble rise velocity up to 500 cm/s be realized in the bubble SOG. The results of the measurements of O II(1Δ) yield, chlorine utilization and water fraction at the exit of the centrifugal bubble SOG are presented. A high O II(1Δ) yield and chlorine utilization higher than 90% have been obtained at chlorine gas loading up to 6 mmole/s per 1 cm2 of the bubbler surface. The ejector COIL powered by centrifugal bubbling SOG demonstrated ~25% of chemical efficiency with specific power 6 kW per 1 litre/s of the BHP volumetric rate.

  1. Flow Analysis of the Cleveland Clinic Centrifugal Pump

    NASA Technical Reports Server (NTRS)

    Veres, Joseph P.; Golding, Leonard A. R.; Smith, William A.; Horvath, David; Medvedev, Alexander

    1997-01-01

    An implantable ventricular assist rotordynamic blood pump is being developed by the Cleveland Clinic Foundation in cooperation with the NASA Lewis Research Center. At the nominal design condition, the pump provides blood flow at the rate of 5 liters per minute at a pressure rise of 100 mm of mercury and a rotative speed of 3000 RPM. Bench testing of the centrifugal pump in a water/glycerin mixture has provided flow and pressure data at several rotative speeds. A one-dimensional empirical based pump flow analysis computer code developed at NASA Lewis Research Center has been used in the design process to simulate the flow in the primary centrifugal pump stage. The computer model was used to size key impeller and volute geometric parameters that influence pressure rise and flow. Input requirements to the computer model include a simple representation of the pump geometry. The model estimates the flow conditions at the design and at off-design operating conditions at the impeller leading and trailing edges and the volute inlet and exit. The output from the computer model is compared to flow and pressure data obtained from bench testing.

  2. Extraction of phenol in wastewater with annular centrifugal contactors.

    PubMed

    Xu, Jin-Quan; Duan, Wu-Hua; Zhou, Xiu-Zhu; Zhou, Jia-Zhen

    2006-04-17

    Solvent extraction is an effective way to treat and recover the phenolic compounds from the high content phenolic wastewater at present. The experimental study on treating the wastewater containing phenol has been carried out with QH-1extractant (the amine mixture) and annular centrifugal contactors. The distribution ratio of phenol was 108.6 for QH-1-phenol system. The mass-transfer process of phenol for the system was mainly controlled by diffusion. When the flow ratio (aqueous/organic) was changed from 1/1 to 4/1, the rotor speed was changed from 2500 to 4000 r/min, and the total flow of two phases was changed from 20 to 70 mL/min, the mass-transfer efficiency E of the single-stage centrifugal contactor was more than 95%. When the flow ratio was changed from 4.4/1 to 4.9/1, the rotor speed was 3000 r/min, and the total flow of two phases was changed from 43.0 to 47.0 mL/min, the extraction rate rho of the three-stage cascade was more than 99%. When 15% NaOH was used for stripping of phenol in QH-1, the stripping efficiency of the three-stage cascade was also more than 99% under the experimental conditions.

  3. Concrete Cleaning, Inc. centrifugal shot blaster: Baseline report; Greenbook (chapter)

    SciTech Connect

    1997-07-31

    The centrifugal shot blaster technology was tested and is being evaluated at Florida International University (FIU) as a baseline technology. In conjunction with FIU`s evaluation of efficiency and cost, this report covers the evaluation conducted for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The centrifugal shot blaster is an electronically operated shot blast machine that has been modified to remove layers of concrete to varying depths. A hardened steel shot propelled at a high rate of speed abrades the surface of the concrete. The depth of material removed is determined by the rate of speed the machine is traveling and the volume of shot being fired into the blast chamber. The steel shot is recycled and used over until it is pulverized into dust, which ends up in the waste container with the concrete being removed. Debris is continually vacuumed by a large dust collection system attached to the shot blaster. The safety and health evaluation during the human factors assessment focused on two main areas: noise and dust.

  4. Concrete Cleaning, Inc. centrifugal shot blaster: Baseline report

    SciTech Connect

    1997-07-31

    The centrifugal shot blaster technology was tested and is being evaluated at Florida International University (FIU) as a baseline technology. In conjunction with FIU`s evaluation of efficiency and cost, this report covers the evaluation conducted for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The centrifugal shot blaster is an electronically operated shot blast machine that has been modified to remove layers of concrete to varying depths. A hardened steel shot propelled at a high rate of speed abrades the surface of the concrete. The depth of material removed is determined by the rate of speed the machine is traveling and the volume of shot being fired into the blast chamber. The steel shot is recycled and used over until it is pulverized into dust, which ends up in the waste container with the concrete being removed. Debris is continually vacuumed by a large dust collection system attached to the shot blaster. The safety and health evaluation during the human factors assessment focused on two main areas: noise and dust.

  5. Evaluation and prediction of blade-passing frequency noise generated by a centrifugal blower

    SciTech Connect

    Ohta, Y.; Outa, E.; Tajima, K.

    1996-07-01

    The blade-passing frequency noise, abbreviated to BPF noise, of a low-specific-speed centrifugal blower is analyzed by separating the frequency response of the transmission passage and the intensity of the noise source. Frequency response has previously been evaluated by the authors using a one-dimensional linear wave model, and the results have agreed well with the experimental response in a practical range of the blower speed. In the present study, the intensity of the noise source is estimated by introducing the quasi-steady model of the blade wake impingement on the scroll surface. The effective location of the noise source is determined by analyzing the cross-correlation between measured data of the blower suction noise and pressure fluctuation on the scroll surface. Then, the surface density distribution of a dipole noise source is determined from pressure fluctuations expressed in terms of quasi-steady dynamic pressure of the traveling blade wake. Finally, the free-field noise level is predicted by integrating the density spectrum of the noise source over the effective source area. The sound pressure level of the blower suction noise is easily predicted by multiplying the free-field noise level by the frequency-response characteristics of the noise transmission passage.

  6. Numerical investigation of nonlinear vibration for rotor-seal system of centrifugal pump

    NASA Astrophysics Data System (ADS)

    Zhou, W. J.; Yang, Y. C.; Xing, G. K.; Wang, L. Q.

    2013-12-01

    The exciting force in the seal is an important factor for the stability of a multiple stage centrifugal pump. With the speed increasing, the rotor system of multiple stage centrifugal pump presents some nonlinear characters. In order to provide supports for the research of nonlinear characters of multiple stage centrifugal pump, a rotor-seal system model of centrifugal pump is presented and the Muszynska nonlinear seal model is used to express the seal exciting force with multiple parameters in the paper. The fourth-order Runge-Kutta method is also used to determine the vibration response at the impeller place and obtain bifurcation diagram, axis orbit, phase diagram as well as Poincaré Map. The bifurcation results show that the rotor-seal system would be stable under a lower speed and change to be unstable as the rotor speed increases. Various multi-periodic motions and quasi-periodic motions are found showing the complicated motions in the rotor-seal system under nonlinear seal forces.

  7. Centrifugal Spinning and Its Energy Storage Applications

    NASA Astrophysics Data System (ADS)

    Yao, Lu

    Lithium-ion batteries (LIBs) and supercapacitors are important electrochemical energy storage systems. LIBs have high specific energy density, long cycle life, good thermal stability, low self-discharge, and no memory effect. However, the low abundance of Li in the Earth's crust and the rising cost of LIBs urge the attempts to develop alternative energy storage systems. Recently, sodium-ion batteries (SIBs) have become an attractive alternative to LIBs due to the high abundance and low cost of Na. Although the specific capacity and energy density of SIBs are not as high as LIBs, SIBs can still be promising power sources for certain applications such as large-scale, stationary grids. Supercapacitors are another important class of energy storage devices. Electric double-layer capacitors (EDLCs) are one important type of supercapacitors and they exhibit high power density, long cycle life, excellent rate capability and environmental friendliness. The potential applications of supercapacitors include memory protection in electronic circuitry, consumer portable electronic devices, and electrical hybrid vehicles. The electrochemical performance of SIBs and EDLCs is largely dependent on the electrode materials. Therefore, development of superior electrodes is the key to achieve highperformance alternative energy storage systems. Recently, one-dimensional nano-/micro-fiber based electrodes have become promising candidates in energy storage because they possess a variety of desirable properties including large specific surface area, well-guided ionic/electronic transport, and good electrode-electrolyte contact, which contribute to enhanced electrochemical performance. Currently, most nano-/micro-fiber based electrodes are prepared via electrospinning method. However, the low production rate of this approach hinders its practical application in the production of fibrous electrodes. Thus, it is significantly important to employ a rapid, low-cost and scalable nano

  8. Dermatoscopic features of central centrifugal cicatricial alopecia.

    PubMed

    Miteva, Mariya; Tosti, Antonella

    2014-09-01

    No data exist on the dermatoscopic findings in central centrifugal cicatricial alopecia (CCCA). We sought to establish the spectrum of dermatoscopic features and their frequency in CCCA. We retrospectively evaluated 153 nonpolarized dermatoscopic images obtained from 51 women with histologically proven CCCA and established a list of 12 dermatoscopic features that were independently scored for each image. Controls included 30 dermatoscopic images from histologically proven cases of scarring traction alopecia and discoid lupus erythematosus. The receiver operating characteristic curve analysis assessed the specificity and sensitivity; Cohen kappa statistics assessed the agreement. Dermatoscopic pathologic correlations were performed on the horizontal sections of 41 of the 51 specimens, which were obtained with dermatoscopy-guided biopsy procedures. Peripilar white gray halo around the emergence of hairs was observed in 94% of patients and was highly specific and sensitive for CCCA in all clinical stages. It corresponds on pathology to the lamellar fibrosis surrounding the outer root sheath. This was a retrospective study. The presence of a peripilar white halo is a dermatoscopic feature that suggests the diagnosis of CCCA in African American patients with mild central thinning, and it is an optimal site from which to obtain a biopsy specimen. Copyright © 2014 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

  9. Gas dynamics in strong centrifugal fields

    SciTech Connect

    Bogovalov, S.V.; Kislov, V.A.; Tronin, I.V.

    2015-03-10

    Dynamics of waves generated by scopes in gas centrifuges (GC) for isotope separation is considered. The centrifugal acceleration in the GC reaches values of the order of 106g. The centrifugal and Coriolis forces modify essentially the conventional sound waves. Three families of the waves with different polarisation and dispersion exist in these conditions. Dynamics of the flow in the model GC Iguasu is investigated numerically. Comparison of the results of the numerical modelling of the wave dynamics with the analytical predictions is performed. New phenomena of the resonances in the GC is found. The resonances occur for the waves polarized along the rotational axis having the smallest dumping due to the viscosity.

  10. Water Drainage from Unsaturated Soils in a Centrifuge Permeameter

    NASA Astrophysics Data System (ADS)

    Ornelas, G.; McCartney, J.; Zhang, M.

    2013-12-01

    This study involves an analysis of water drainage from an initially saturated silt layer in a centrifuge permeameter to evaluate the hydraulic properties of the soil layer in unsaturated conditions up to the point where the water phase becomes discontinuous. These properties include the soil water retention curve (SWRC) and the hydraulic conductivity function (HCF). The hydraulic properties of unsaturated silt are used in soil-atmosphere interaction models that take into account the role of infiltration and evaporation of water from soils due to atmospheric interaction. These models are often applied in slope stability analyses, landfill cover design, aquifer recharge analyses, and agricultural engineering. The hydraulic properties are also relevant to recent research concerning geothermal heating and cooling, as they can be used to assess the insulating effects of soil around underground heat exchangers. This study employs a high-speed geotechnical centrifuge to increase the self-weight of a compacted silt specimen atop a filter plate. Under a centrifuge acceleration of N times earth's gravity, the concept of geometric similitude indicates that the water flow process in a small-scale soil layer will be similar to those in a soil layer in the field that is N times thicker. The centrifuge acceleration also results in an increase in the hydraulic gradient across the silt specimen, which causes water to flow out of the pores following Darcy's law. The drainage test was performed until the rate of liquid water flow out of the soil layer slowed to a negligible level, which corresponds to the transition point at which further water flow can only occur due to water vapor diffusion following Fick's law. The data from the drainage test in the centrifuge were used to determine the SWRC and HCF at different depths in the silt specimen, which compared well with similar properties defined using other laboratory tests. The transition point at which liquid water flow stopped (and

  11. High Technology Centrifugal Compressor for Commercial Air Conditioning Systems

    SciTech Connect

    Ruckes, John

    2006-04-15

    R&D Dynamics, Bloomfield, CT in partnership with the State of Connecticut has been developing a high technology, oil-free, energy-efficient centrifugal compressor called CENVA for commercial air conditioning systems under a program funded by the US Department of Energy. The CENVA compressor applies the foil bearing technology used in all modern aircraft, civil and military, air conditioning systems. The CENVA compressor will enhance the efficiency of water and air cooled chillers, packaged roof top units, and other air conditioning systems by providing an 18% reduction in energy consumption in the unit capacity range of 25 to 350 tons of refrigeration The technical approach for CENVA involved the design and development of a high-speed, oil-free foil gas bearing-supported two-stage centrifugal compressor, CENVA encompassed the following high technologies, which are not currently utilized in commercial air conditioning systems: Foil gas bearings operating in HFC-134a; Efficient centrifugal impellers and diffusers; High speed motors and drives; and System integration of above technologies. Extensive design, development and testing efforts were carried out. Significant accomplishments achieved under this program are: (1) A total of 26 builds and over 200 tests were successfully completed with successively improved designs; (2) Use of foil gas bearings in refrigerant R134a was successfully proven; (3) A high speed, high power permanent magnet motor was developed; (4) An encoder was used for signal feedback between motor and controller. Due to temperature limitations of the encoder, the compressor could not operate at higher speed and in turn at higher pressure. In order to alleviate this problem a unique sensorless controller was developed; (5) This controller has successfully been tested as stand alone; however, it has not yet been integrated and tested as a system; (6) The compressor successfully operated at water cooled condensing temperatures Due to temperature

  12. Meteor Crater: Energy of formation - Implications of centrifuge scaling

    NASA Technical Reports Server (NTRS)

    Schmidt, R. M.

    1980-01-01

    Recent work on explosive cratering has demonstrated the utility of performing subscale experiments on a geotechnic centrifuge to develop scaling rules for very large energy events. The present investigation is concerned with an extension of this technique to impact cratering. Experiments have been performed using a projectile gun mounted directly on the centrifuge rotor to launch projectiles into a suitable soil container undergoing centripetal accelerations in excess of 500 G. The pump tube of a two-stage light-gas gun was used to attain impact velocities of approximately 2 km/sec. The results of the experiments indicate that the energy of formation of any large impact crater depends upon the impact velocity. This dependence, shown for the case of Meteor Crater, is consistent with analogous results for the specific energy dependence of explosives and is expected to persist to impact velocities in excess of 25 km/sec.

  13. Evolutionary Optimization of Centrifugal Nozzles for Organic Vapours

    NASA Astrophysics Data System (ADS)

    Persico, Giacomo

    2017-03-01

    This paper discusses the shape-optimization of non-conventional centrifugal turbine nozzles for Organic Rankine Cycle applications. The optimal aerodynamic design is supported by the use of a non-intrusive, gradient-free technique specifically developed for shape optimization of turbomachinery profiles. The method is constructed as a combination of a geometrical parametrization technique based on B-Splines, a high-fidelity and experimentally validated Computational Fluid Dynamic solver, and a surrogate-based evolutionary algorithm. The non-ideal gas behaviour featuring the flow of organic fluids in the cascades of interest is introduced via a look-up-table approach, which is rigorously applied throughout the whole optimization process. Two transonic centrifugal nozzles are considered, featuring very different loading and radial extension. The use of a systematic and automatic design method to such a non-conventional configuration highlights the character of centrifugal cascades; the blades require a specific and non-trivial definition of the shape, especially in the rear part, to avoid the onset of shock waves. It is shown that the optimization acts in similar way for the two cascades, identifying an optimal curvature of the blade that both provides a relevant increase of cascade performance and a reduction of downstream gradients.

  14. Modeling of Centrifugal Force Field and the Effect on Filling and Solidification in Centrifugal Casting

    NASA Astrophysics Data System (ADS)

    Sheng, Wenbin; Ma, Chunxue; Gu, Wanli

    2011-06-01

    Based on the steady flow in a tube, a mathematical model has been established for the consideration of centrifuging force field by combining the equations of continuity, conservation of momentum and general energy. Effects of centrifugal field on the filling and solidification are modeled by two accessional terms: centrifugal force and Chorios force. In addition, the transfer of heat by convection is considered to achieve a coupling calculation of velocity field and temperature field. The solution of pressure item is avoided by introducing the stream function ψ(x,y) and the eddy function ξ(x,y). Corresponding difference formats for the simultaneous equations of centrifugal filling, the accessional terms and the solidifying latent heat have been established by the finite difference technique. Furthermore, the centrifugal filling and solidification processes in a horizontal tube are summarized to interpret the mechanism by which internal defects are formed in centrifugal castings.

  15. Effects of Centrifugal Force and Centrifugation Time on the Sedimentation of Plant Organelles 1

    PubMed Central

    Nagahashi, Jerry; Hiraike, Kathleen

    1982-01-01

    The effect of centrifugal force and length of centrifugation time on the sedimentation of plant organelles was determined for corn (Zea mays L.) root homogenates. A centrifugal force of 6000g for at least 20 minutes was necessary to pellet 90% of the mitochondrial marker (cytochrome c oxidase). This initial centrifugation step is optimal for separating mitochondria from microsomes, since cross-contamination of endoplasmic reticulum and plasma membrane vesicles with mitochondria is minimized. Centrifugal forces of 8000g or 10,000g for 20 minutes and 13,000g for 15 minutes pellet 90% of the mitochondrial marker; however, these centrifugation conditions also sediment more plasma membrane and endoplasmic reticulum. PMID:16662245

  16. Numerical simulation on dimension decrease for annular casing of one centrifugal boiler circulation pump

    NASA Astrophysics Data System (ADS)

    Fan, Y. Z.; Zuo, Z. G.; Liu, S. H.; Wu, Y. L.; Sha, Y. J.

    2012-11-01

    Primary formulation derivation indicates that the dimension of one existing centrifugal boiler circulation pump casing is too large. As great manufacture cost can be saved by dimension decrease, a numerical simulation research is developed in this paper on dimension decrease for annular casing of this pump with a specific speed equaling to 189, which aims at finding an appropriately smaller dimension of the casing while hydraulic performance and strength performance will hardly be changed according to the requirements of the cooperative company. The research object is one existing centrifugal pump with a diffuser and a semi-spherical annular casing, working as the boiler circulation pump for (ultra) supercritical units in power plants. Dimension decrease, the modification method, is achieved by decreasing the existing casing's internal radius (marked as "Ri0") while keeping the wall thickness. The research analysis is based on primary formulation derivation, CFD (Computational Fluid Dynamics) simulation and FEM (Finite Element Method) simulation. Primary formulation derivation estimates that a design casing's internal radius should be less than 0.75 Ri0. CFD analysis indicates that smaller casing with 0.75 Ri0 has a worse hydraulic performance when working at large flow rates and a better hydraulic performance when working at small flow rates. In consideration of hydraulic performance and dimension decrease, an appropriate casing's internal radius is determined, which equals to 0.875 Ri0. FEM analysis then confirms that modified pump casing has nearly the same strength performance as the existing pump casing. It is concluded that dimension decrease can be an economical method as well as a practical method for large pumps in engineering fields.

  17. Improved methodology for the quantitative analysis of mixtures by band centrifugation: reversible equilibration in immunoglobulin preparations.

    PubMed

    Kranz, T; Schmidt, K H

    1979-01-01

    Double-sector aluminium centerpieces are modified for use in analytical high-speed band centrifugation up to 60,000 rpm. A method has been developed for testing IG preparations according to administrative regulations with special regard to precision and reproducibility. The proposed band-forming centrifugation method with scanner registration in UV absorption optics and special evaluation of the curves gives values in comparison to well-known procedures by Svedberg and Pedersen. Subjective and systematic errors are especially estimated with this method and the sensitivity is best suited to automatic computerization and results are therefore readily available at the end of the centrifuge run within a few minutes. Investigations have been undertaken to analyze reversible equilibration in immunoglobulin preparations; the results are discussed.

  18. Estimating soil hydraulic parameters from transient flow experiments in a centrifuge using parameter optimization technique

    USGS Publications Warehouse

    Simunek, J.; Nimmo, J.R.

    2005-01-01

    A modified version of the Hydrus software package that can directly or inversely simulate water flow in a transient centrifugal field is presented. The inverse solver for parameter estimation of the soil hydraulic parameters is then applied to multirotation transient flow experiments in a centrifuge. Using time-variable water contents measured at a sequence of several rotation speeds, soil hydraulic properties were successfully estimated by numerical inversion of transient experiments. The inverse method was then evaluated by comparing estimated soil hydraulic properties with those determined independently using an equilibrium analysis. The optimized soil hydraulic properties compared well with those determined using equilibrium analysis and steady state experiment. Multirotation experiments in a centrifuge not only offer significant time savings by accelerating time but also provide significantly more information for the parameter estimation procedure compared to multistep outflow experiments in a gravitational field. Copyright 2005 by the American Geophysical Union.

  19. Gas centrifuge with driving motor

    DOEpatents

    Dancy, Jr., William H.

    1976-01-01

    1. A centrifuge for separating gaseous constituents of different masses comprising a vertical tubular rotor, means for introducing a gas mixture of different masses into said rotor and means for removing at least one of the gas components from the rotor, a first bearing means supporting said rotor at one end for rotational movement, a support, a damping bearing mounted on said support, a shaft fixed to said rotor at the opposite end and mechanically connecting said rotor to said damping bearing, a cup-shaped tube of electrically conductive, non-magnetic material in coaxial relationship with said shaft, the open end of said tube extending away from said rotor and the closed end of said tube being directly secured to the adjacent end of the rotor, an annular core of magnetic material fixedly mounted on said support so as to be disposed within said tube and around said shaft, and a second annular magnetic core with coils arranged thereon to receive polyphase current to produce a rotating magnetic field traversing the circumference of said tube, fixedly mounted on said support so as to surround said tube, the size of said first annular core and said second annular core being such as to permit limited radial displacement of said shaft and said tube.

  20. ROTATIONAL INSTABILITIES AND CENTRIFUGAL HANGUP

    SciTech Connect

    K. NEW; J. CENTRELLA

    2000-12-01

    One interesting class of gravitational radiation sources includes rapidly rotating astrophysical objects that encounter dynamical instabilities. We have carried out a set of simulations of rotationally induced instabilities in differentially rotating polytropes. An n=1.5 polytrope with the Maclaurin rotation law will encounter the m=2 bar instability at T/{vert_bar}W{vert_bar} {ge} 0.27. Our results indicate that the remnant of this in-stability is a persistent bar-like structure that emits a long-lived gravitational radiation signal. Furthermore, dynamical instability is shown to occur in n=3.33 polytropes with the j-constant rotation law at T/{vert_bar}W{vert_bar} {ge} 0:14. In this case, the dominant mode of instability is m=1. Such instability may allow a centrifugally-hung core to begin collapsing to neutron star densities on a dynamical timescale. If it occurs in a supermassive star, it may produce gravitational radiation detectable by LISA.

  1. Optical detection strategies for centrifugal microfluidic platforms

    NASA Astrophysics Data System (ADS)

    King, Damien; O'Sullivan, Mary; Ducrée, Jens

    2014-01-01

    Centrifugal microfluidic systems have become one of the principal platforms for implementing bioanalytical assays, most notably for biomedical point-of-care diagnostics. These so-called 'lab-on-a-disc' systems primarily utilise the rotationally controlled centrifugal field in combination with capillary forces to automate a range of laboratory unit operations (LUOs) for sample preparation, such as metering, aliquoting, mixing and extraction for biofluids as well as sorting, isolation and counting of bioparticles. These centrifugal microfluidic LUOs have been regularly surveyed in the literature. However, even though absolutely essential to provide true sample-to-answer functionality of lab-on-a-disc platforms, systematic examination of associated, often optical, read-out technologies has been so far neglected. This review focusses on the history and state-of-the-art of optical read-out strategies for centrifugal microfluidic platforms, arising (commercial) application potential and future opportunities.

  2. Crew Training - Apollo 8 (Centrifuge) - MSC

    NASA Image and Video Library

    1968-11-05

    S68-53186 (1 Nov. 1968) --- Astronaut Frank Borman, Apollo 8 commander, egresses the gondola in Building 29 after centrifuge training in the Manned Spacecraft Center's (MSC) Flight Acceleration Facility (FAF).

  3. Combination Of Investment And Centrifugal Casting

    NASA Technical Reports Server (NTRS)

    Creeger, Gordon A.

    1994-01-01

    Modifications, including incorporation of centrifugal casting, made in investment-casting process reducing scrap rate. Used to make first- and second-stage high-pressure-fuel-turbopump nozzles, containing vanes with thin trailing edges and other thin sections. Investment mold spun for short time while being filled, and stopped before solidification occurs. Centrifugal force drives molten metal into thin trailing edges, ensuring they are filled. With improved filling, preheat and pour temperatures reduced and solidification hastened so less hot tearing.

  4. Renal Response to Chronic Centrifugation in Rats

    NASA Technical Reports Server (NTRS)

    Ortiz, Rudy M.; Wang, T. J.; Corbin, B. J.; Wade, C. E.; Hargens, Alan R. (Technical Monitor)

    1996-01-01

    Previously reported effects of chronic centrifugation on renal function in mammals are contradictory. The present study was conducted as an effort to provide a comprehensive analysis of renal response to chronic centrifugation (12 days at +2 Gz). Sixteen male Sprague-Dawley rats (210-230 g) were used: eight centrifuged (EC) and eight off centrifuge controls (OCC). During centrifugation EC had lower body weight and food consumption. EC showed a decrease (72%) in water intake for the first two days (T1 and T2) followed by significant increases from T4-T6. EC urine output increased two-fold over the first four days, returning to baseline by T9. EC urea excretion was elevated on T3 through T5. Creatinine, Na(+), K(+), and osmolar excretion were lower than OCC over the last four days of the study. Assuming constant plasma osmolarity and creatinine levels, EC free water clearance (C(sub H2O)) was elevated significantly on T4 when the peak urine output was exhibited. EC also had a greater C(sub H2O) over the last four days, associated with a significantly lower osmolar clearance and GFR. The initial diuresis exhibited during centrifugation can be attributed to a reduced water resorption and increased urea excretion. This diuresis was mediated independent of changes in GFR over the first eight days. However, differences in excretion seen after eight days of centrifugation are probably GFR mediated which would imply animals established a new homeostatic setpoint by that time. Centrifugation elicites an acute alteration in fluid homeostasis followed by adaptation within a week.

  5. Combination Of Investment And Centrifugal Casting

    NASA Technical Reports Server (NTRS)

    Creeger, Gordon A.

    1994-01-01

    Modifications, including incorporation of centrifugal casting, made in investment-casting process reducing scrap rate. Used to make first- and second-stage high-pressure-fuel-turbopump nozzles, containing vanes with thin trailing edges and other thin sections. Investment mold spun for short time while being filled, and stopped before solidification occurs. Centrifugal force drives molten metal into thin trailing edges, ensuring they are filled. With improved filling, preheat and pour temperatures reduced and solidification hastened so less hot tearing.

  6. Renal Response to Chronic Centrifugation in Rats

    NASA Technical Reports Server (NTRS)

    Ortiz, Rudy M.; Wang, T. J.; Corbin, B. J.; Wade, C. E.; Hargens, Alan R. (Technical Monitor)

    1996-01-01

    Previously reported effects of chronic centrifugation on renal function in mammals are contradictory. The present study was conducted as an effort to provide a comprehensive analysis of renal response to chronic centrifugation (12 days at +2 Gz). Sixteen male Sprague-Dawley rats (210-230 g) were used: eight centrifuged (EC) and eight off centrifuge controls (OCC). During centrifugation EC had lower body weight and food consumption. EC showed a decrease (72%) in water intake for the first two days (T1 and T2) followed by significant increases from T4-T6. EC urine output increased two-fold over the first four days, returning to baseline by T9. EC urea excretion was elevated on T3 through T5. Creatinine, Na(+), K(+), and osmolar excretion were lower than OCC over the last four days of the study. Assuming constant plasma osmolarity and creatinine levels, EC free water clearance (C(sub H2O)) was elevated significantly on T4 when the peak urine output was exhibited. EC also had a greater C(sub H2O) over the last four days, associated with a significantly lower osmolar clearance and GFR. The initial diuresis exhibited during centrifugation can be attributed to a reduced water resorption and increased urea excretion. This diuresis was mediated independent of changes in GFR over the first eight days. However, differences in excretion seen after eight days of centrifugation are probably GFR mediated which would imply animals established a new homeostatic setpoint by that time. Centrifugation elicites an acute alteration in fluid homeostasis followed by adaptation within a week.

  7. Isolation of symbiotic dinoflagellates by centrifugal elutriation

    SciTech Connect

    Bird, A.E.; Quinn, R.J.

    1986-01-01

    Centrifugal elutriation, a method combining centripetal liquid flow with centrifugal force, has been used to isolate symbiotic dinoflagellates from a cnidarian host. The elutriated cells were shown to be viable by photosynthetic incorporation of /sup 14/CO/sub 2/ and low release of photosynthetic products into the incubation medium. The level of contamination by clinging debris was low and by host solids was negligible.

  8. In vitro pulsatility analysis of axial-flow and centrifugal-flow left ventricular assist devices.

    PubMed

    Stanfield, J Ryan; Selzman, Craig H

    2013-03-01

    Recently, continuous-flow ventricular assist devices (CF-VADs) have supplanted older, pulsatile-flow pumps, for treating patients with advanced heart failure. Despite the excellent results of the newer generation devices, the effects of long-term loss of pulsatility remain unknown. The aim of this study is to compare the ability of both axial and centrifugal continuous-flow pumps to intrinsically modify pulsatility when placed under physiologically diverse conditions. Four VADs, two axial- and two centrifugal-flow, were evaluated on a mock circulatory flow system. Each VAD was operated at a constant impeller speed over three hypothetical cardiac conditions: normo-tensive, hypertensive, and hypotensive. Pulsatility index (PI) was compared for each device under each condition. Centrifugal-flow devices had a higher PI than that of axial-flow pumps. Under normo-tension, flow PI was 0.98 ± 0.03 and 1.50 ± 0.02 for the axial and centrifugal groups, respectively (p < 0.01). Under hypertension, flow PI was 1.90 ± 0.16 and 4.21 ± 0.29 for the axial and centrifugal pumps, respectively (p = 0.01). Under hypotension, PI was 0.73 ± 0.02 and 0.78 ± 0.02 for the axial and centrifugal groups, respectively (p = 0.13). All tested CF-VADs were capable of maintaining some pulsatile-flow when connected in parallel with our mock ventricle. We conclude that centrifugal-flow devices outperform the axial pumps from the basis of PI under tested conditions.

  9. Mapping size distributions of parenteral fluorocarbon emulsions by a novel method of centrifugal sedimentation followed by densitometry.

    PubMed

    Apte, S P; Turco, S J

    1992-01-01

    A novel method for characterization of size distributions of parenteral fluorocarbon emulsions is described. Prepared emulsions were centrifuged to sediment droplets above predetermined diameters out of a known supernatant sample volume using the Bostok-Stoke's equation. Centrifugation times may be calculated using centrifuge parameters and physical properties of the fluorocarbon oil phase and the dispersion medium. The fluorocarbon content of the supernatant sample volume at successive centrifugation times was determined both by densitometry and by Gas Chromatography. A close correlation was found between the two methods. The density data was processed and converted into a volume distribution histogram by means of a program written in BASIC. The speed, simplicity of use, non reliance on costly equipment and good correlation to absolute particle counting methods makes the density method suitable for submicron size characterization.

  10. Determination of the Heat Transfer Coefficient at the Metal-Mold Interface During Centrifugal Casting

    NASA Astrophysics Data System (ADS)

    Vacca, Santiago; Martorano, Marcelo A.; Heringer, Romulo; Boccalini, Mário

    2015-05-01

    The heat transfer coefficient at the metal-mold interface ( h MM) has been determined for the first time during the centrifugal casting of a Fe-C alloy tube using the inverse solution method. To apply this method, a centrifugal casting experiment was carried out to measure cooling curves within the tube wall under a mold rotation speed of 900 rpm, imposing a centrifugal force 106 times as large as the gravity force (106 G). As part of the solution method, a comprehensive heat transfer model of the centrifugal casting was also developed and coupled to an optimization algorithm. Finally, the evolution of h MM with time that gives the minimum squared error between measured and calculated cooling curves was obtained. The determined h MM is approximately 870 W m-2 K-1 immediately after melt pouring, decreasing to about 50 W m-2 K-1 when the average temperature of the tube is ~973 K (700 °C), after the end of solidification. Despite the existence of a centrifugal force that could enhance the metal-mold contact, these values are lower than those generally reported for static molds with or without an insulating coating at the mold inner surface. The implemented model shows that the heat loss by radiation is dominant over that by convection at the tube inner surface, causing the formation of a solidification front that meets another front coming from the outer surface of the tube.

  11. The use of a solid-bowl centrifuge for ultrafine coal thickening

    SciTech Connect

    Pinkerton, A.P.; Klima, M.S.; Morrison, J.L.; Miller, B.G.

    2000-07-01

    Testing was carried out to investigate the use of a solid-bowl (decanter) centrifuge for thickening ultrafine coal-water slurries. This study was conducted for Electric Power Research Institute's (EPRI's) Upgraded Coal Interest Group (UCIG) to evaluate ultrafine dewatering technologies. The objective was to increase the solids concentration of an ultrafine coal discard stream to a level suitable for use as a coal-water slurry fuel, while maximizing overall solids recovery. The feed material was collected from the combined discharge (centrate) streams from several screen-bowl centrifuges, which are currently being used in a commercial coal cleaning facility to dewater froth flotation product. The centrate averages 5% solids by weight and contains nearly 60% material finer than 10 {micro}m. This study examined the effects of operating conditions on centrifuge performance, including centrifuge bowl and scroll speeds, and feed solids concentration. The effects of flocculation addition on centrifuge performance and slurry rheology were also examined. The results indicated that solids concentrations exceeding 55% were obtained in nearly all cases.

  12. Development of special rotor for centrifugal separation of isotopes in solid pure metals.

    PubMed

    Ono, Masao; Sueyoshi, Masanori; Okayasu, Satoru; Hao, Ting; Esaka, Fumitaka; Osawa, Takahito; Iguchi, Yusuke; Mashimo, Tsutomu

    2009-08-01

    A prototype rotor with two grooves for the multistage centrifugal isotope separation in solid state was developed to test a new idea. This idea is based on the sedimentation of constitutional atoms in solid. In the performance test using indium specimen, it is verified that the developed rotor can receive all injected molten-indium droplets from an automatic raw-material feeding system even at the high rotational speed of 97,000 rpm without the loss of rotational stability, and the received indium specimens can be transferred in/between two grooves through the plastic flow under the influence of strong centrifugal force even in the solid state. The isotope ratio of centrifuged indium specimens was analyzed employing the secondary ion mass spectrometry, and it is confirmed that intended isotope separation by the centrifugation is realized in the solid state. The developed rotor can be used to perform the isotope separation on at least solid metals under the conditions of up to 400 degrees C in specimen temperature and 0.4x10(6)g in centrifugal force field.

  13. A novel centrifuge for animal physiological researches in hypergravity and variable gravity forces

    NASA Astrophysics Data System (ADS)

    Kumei, Yasuhiro; Hasegawa, Katsuya; Inoue, Katarzyna; Zeredo, . Jorge; Kimiya Narikiyo, .; Maezawa, Yukio; Yuuki Watanabe, .; Aou, Shuji

    2012-07-01

    Understanding the physiological responses to altered gravitational environments is essential for space exploration and long-term human life in space. Currently available centrifuges restrict experimentation due to limited space for laboratory equipments. We developed a medium-sized disc-type centrifuge to conduct ground-based studies on animal physiological response to hypergravity and variable gravity forces, which features the following advantages: 1) It enables simultaneous examination into the effects of various gravity levels including rotation control. 2) Beside the constant G force, variable G forces (delta-G) can be loaded to generate gravitational acceleration and deceleration. 3) Multiple imaging techniques can be used, such as high-speed video (16 channels wireless) and photography, X-ray, and infra-red imaging. 4) Telemetry is available on the disc table of the centrifuge through 128-channel analog and 32-channel digital signals, with sampling rate of 100 kHz for 2 hours. Our dynamic-balanced centrifuge can hold payloads of 600 kg that enable experimentation on various models of living organisms, from cells to animals and plants. We use this novel centrifuge for neurochemical and neurophysiological approaches such as microdialysis and telemetrical recording of neuronal activity in the rat brain. Financial supports from JSPS to K. Hasegawa (2011) and from JAXA to Y. Kumei (2011).

  14. Transient thermal analysis of solidification in a centrifugal casting for composite materials containing particle segregation

    SciTech Connect

    Kang, C.G.; Rohatgi, P.K.

    1996-04-01

    One-dimensional heat-transfer analysis during centrifugal casting of aluminum alloy and copper base metal matrix composites containing Al{sub 2}O{sub 3}, SiC{sub p}, and graphite particles has been studied. The model of the particle segregation is calculated by varying the volume fraction during centrifugal casting, and a finite difference technique has been adopted. The results indicate that the thickness of the region in which dispersed particles are segregated due to the centrifugal force is strongly influenced by the speed of rotation of the mold, the solidification time, and the density difference between the base alloy and the reinforcement. In the case where the base alloy density is larger than that of the particles, the thickness of the particle-rich region near the inner periphery decreases with an increase in speed, thereby increasing the volume fraction of dispersion. The solidification time of the casting is also dependent upon the speed of rotation of the mold, and it decreases with an increase in speed. This study also indicates that the presence of particles increases the solidification time of the casting.

  15. Determining the Effect of Centrifugal Force on the Desired Growth and Properties of PCPDTBT as p-Type Nanowires

    NASA Astrophysics Data System (ADS)

    Doris, Muhamad; Aziz, Fakhra; Alhummiany, Haya; Bawazeer, Tahani; Alsenany, Nourah; Mahmoud, Alaa; Zakaria, Rozalina; Sulaiman, Khaulah; Supangat, Azzuliani

    2017-01-01

    In this study, low-bandgap polymer poly{[4,4-bis(2-ethylhexyl)-cyclopenta-(2,1- b;3,4- b')dithiophen]-2,6-diyl- alt-(2,1,3-benzothiadiazole)-4,7-diyl} (PCPDTBT) nanostructures have been synthesized via a hard nanoporous alumina template of centrifugal process. Centrifuge has been used to infiltrate the PCPDTBT solution into the nanoporous alumina by varying the rotational speeds. The rotational speed of centrifuge is directly proportional to the infiltration force that penetrates into the nanochannels of the template. By varying the rotational speed of centrifuge, different types of PCPDTBT nanostructures are procured. Infiltration force created during the centrifugal process has been found a dominant factor in tuning the morphological, optical, and structural properties of PCPDTBT nanostructures. The field emission scanning electron microscopy (FESEM) images proved the formation of nanotubes and nanowires. The energy-dispersive X-ray spectroscope (EDX) analysis showed that the nanostructures were composed of PCPDTBT with complete dissolution of the template.

  16. Centrifugal Microfluidic System for Nucleic Acid Amplification and Detection

    PubMed Central

    Miao, Baogang; Peng, Niancai; Li, Lei; Li, Zheng; Hu, Fei; Zhang, Zengming; Wang, Chaohui

    2015-01-01

    We report here the development of a rapid PCR microfluidic system comprising a double-shaft turntable and centrifugal-based disc that rapidly drives the PCR mixture between chambers set at different temperatures, and the bidirectional flow improved the space utilization of the disc. Three heating resistors and thermistors maintained uniform, specific temperatures for the denaturation, annealing, and extension steps of the PCR. Infrared imaging showed that there was little thermal interference between reaction chambers; the system enabled the cycle number and reaction time of each step to be independently adjusted. To validate the function and efficiency of the centrifugal microfluidic system, a 350-base pair target gene from the hepatitis B virus was amplified and quantitated by fluorescence detection. By optimizing the cycling parameters, the reaction time was reduced to 32 min as compared to 120 min for a commercial PCR machine. DNA samples with concentrations ranging from 10 to 106 copies/mL could be quantitatively analyzed using this system. This centrifugal-based microfluidic platform is a useful system and possesses industrialization potential that can be used for portable diagnostics. PMID:26556354

  17. Water Containment Systems for Testing High-Speed Flywheels

    NASA Technical Reports Server (NTRS)

    Trase, Larry; Thompson, Dennis

    2006-01-01

    Water-filled containers are used as building blocks in a new generation of containment systems for testing high-speed flywheels. Such containment systems are needed to ensure safety by trapping high-speed debris in the event of centrifugal breakup or bearing failure. Traditional containment systems for testing flywheels consist mainly of thick steel rings. The effectiveness of this approach to shielding against high-speed debris was demonstrated in a series of tests.

  18. Creating porous tubes by centrifugal forces for soft tissue application.

    PubMed

    Dalto, P D; Shoichet, M S

    2001-10-01

    Chemically crosslinked poly(2-hydroxyethyl methacrylate) (PHEMA) tubes were synthesized by applying centrifugal forces to propagating polymer chains in solution. Initiated monomer solutions, with a composition typical for PHEMA sponges, were placed into a cylindrical mold that was rotated about its long axis. As polymerization proceeded, phase separated PHEMA formed a sediment at the periphery under centrifugal action. The solvent remained in the center of the mold while the PHEMA phase gelled, resulting in a tube. By controlling the rotational speed and the formulation chemistry (i.e., monomer, initiator and crosslinking agent concentrations), the tube dimensions and wall morphology were manipulated. Tube manufacture was limited by a critical casting concentration [M]c, above which only rods formed. All tubes had an outer diameter of 2.4 mm, reflecting the internal diameter of the mold and a wall thickness of approximately 40-400 microm. Wall morphologies varied from interconnecting polymer and water phases to a closed cell, gel-like, structure. Concentric tubes were successfully prepared by using formulations that enhanced phase separation over gelation/network formation. This was achieved by using formulations with lower concentrations of monomer and crosslinking agent and higher concentrations of initiator. This technique offers a new approach to the synthesis of polymeric tubes for use in soft tissue applications, such as nerve guidance channels.

  19. Numerical Study of Unsteady Flow in Centrifugal Cold Compressor

    NASA Astrophysics Data System (ADS)

    Zhang, Ning; Zhang, Peng; Wu, Jihao; Li, Qing

    In helium refrigeration system, high-speed centrifugal cold compressor is utilized to pumped gaseous helium from saturated liquid helium tank at low temperature and low pressure for producing superfluid helium or sub-cooled helium. Stall and surge are common unsteady flow phenomena in centrifugal cold compressors which severely limit operation range and impact efficiency reliability. In order to obtain the installed range of cold compressor, unsteady flow in the case of low mass flow or high pressure ratio is investigated by the CFD. From the results of the numerical analysis, it can be deduced that the pressure ratio increases with the decrease in reduced mass flow. With the decrease of the reduced mass flow, backflow and vortex are intensified near the shroud of impeller. The unsteady flow will not only increase the flow loss, but also damage the compressor. It provided a numerical foundation of analyzing the effect of unsteady flow field and reducing the flow loss, and it is helpful for the further study and able to instruct the designing.

  20. Prediction of active control of subsonic centrifugal compressor rotating stall

    NASA Technical Reports Server (NTRS)

    Lawless, Patrick B.; Fleeter, Sanford

    1993-01-01

    A mathematical model is developed to predict the suppression of rotating stall in a centrifugal compressor with a vaned diffuser. This model is based on the employment of a control vortical waveform generated upstream of the impeller inlet to damp weak potential disturbances that are the early stages of rotating stall. The control system is analyzed by matching the perturbation pressure in the compressor inlet and exit flow fields with a model for the unsteady behavior of the compressor. The model was effective at predicting the stalling behavior of the Purdue Low Speed Centrifugal Compressor for two distinctly different stall patterns. Predictions made for the effect of a controlled inlet vorticity wave on the stability of the compressor show that for minimum control wave magnitudes, on the order of the total inlet disturbance magnitude, significant damping of the instability can be achieved. For control waves of sufficient amplitude, the control phase angle appears to be the most important factor in maintaining a stable condition in the compressor.

  1. Mechanical properties and microstructure of centrifugally cast alloy 718

    NASA Astrophysics Data System (ADS)

    Michel, D. J.; Smith, H. H.

    1985-07-01

    The relationship between the microstructure and mechanical properties of alloy 718 was investigated for two discs centrifugally cast at 50 and 200 rpm and given a duplex age heat treatment. The results of mechanical property tests at temperatures from 426 to 649 °C showed that the tensile yield and ultimate strength levels of both castings were similar. However, the creep-rupture properties were considerably enhanced for the casting produced at 200 rpm. Comparison of the radial and transverse creep properties of each disc indicated that creep life was generally independent of orientation, but ductility was greatest for specimens oriented transverse to the radial direction of the casting. Fatigue crack propagation performance was not greatly influenced by orientation or mold speed parameters and was comparable to wrought alloy 718 when compared on the basis of stress intensity factor range. The centrifugal casting process was found to produce a homogeneous microstructure free of porosity but with the expected segregation of solute alloying elements to Laves and carbide phases. The effect of the as-cast microstructure on the mechanical behavior and the potential influence of hot isostatic pressing to improve the microstructure are discussed.

  2. Magnetically suspended centrifugal blood pump with a self bearing motor.

    PubMed

    Masuzawa, Toru; Onuma, Hiroyuki; Kim, Seung-Jong; Okada, Yohji

    2002-01-01

    A magnetically suspended centrifugal blood pump with a self bearing motor has been developed for long-term ventricular assistance. A rotor of the self bearing motor is actively suspended and rotated by an electromagnetic field without mechanical bearings. Radial position of the rotor is controlled actively, and axial position of the rotor is passively stable within the thin rotor structure. An open impeller and a semiopened impeller were examined to determine the best impeller structure. The outer diameter and height of the impeller are 63 and 34 mm, respectively. Both the impellers indicated similar pump performance. Single volute and double volute structures were also tested to confirm the performance of the double volute. Power consumption for levitation and radial displacement of the impeller with a rotational speed of 1,500 rpm were 0.7 W and 0.04 mm in the double volute, while those in the single volute were 1.3 W and 0.07 mm, respectively. The stator of the self bearing motor was redesigned to avoid magnetic saturation and improve motor performance. Maximum flow rate and pressure head were 9 L/min and 250 mm Hg, respectively. The developed magnetically suspended centrifugal blood pump is a candidate for an implantable left ventricular assist device.

  3. Prediction of leakage flow in a shrouded centrifugal blood pump.

    PubMed

    Teo, Ji-Bin; Chan, Weng-Kong; Wong, Yew-Wah

    2010-09-01

    This article proposes a phenomenological model to predict the leakage flow in the clearance gap of shrouded centrifugal blood pumps. A good washout in the gap clearance between the rotating impeller surfaces and volute casing is essential to avoid thrombosis. However, excessive leakage flow will result in higher fluid shear stress that may lead to hemolysis. Computational fluid dynamics (CFD) analysis was performed to investigate the leakage flow in a miniaturized shrouded centrifugal blood pump operating at a speed of 2000 rpm. Based on an analytical model derived earlier, a phenomenological model is proposed to predict the leakage flow. The leakage flow rate is found to be proportional to h(α) , where h is the gap size and the exponent α ranges from 2.955 to 3.15 for corresponding gap sizes of 0.2-0.5 mm. In addition, it is observed that α is a linear function of the gap size h. The exponent α compensates for the variation of pressure difference along the circumferential direction as well as inertia effects that are dominant for larger gap clearances. The proposed model displays good agreement with computational results. The CFD analysis also showed that for larger gap sizes, the total leakage flow rate is of the same order of magnitude as the operating flow rate, thus suggesting low volumetric efficiency.

  4. Influence of hydrophibization of impellers of centrifugal pumps on their operating characteristics

    NASA Astrophysics Data System (ADS)

    Volkov, A. V.; Parygin, A. G.; Naumov, A. V.; Vikhlyantsev, A. A.; Šoukal, J.; Sedlář, M.; Komárek, M.

    2016-12-01

    This work presents experimental estimation results of changing of basic operation characteristics of a group of centrifugal pumps covering a range of values of dimensionless power-speed coefficient n s from 33 to 330 after hydrophobization of their impellers' surfaces. Hydrophobization of functional surfaces of impellers in all experiments was performed by formation of structures of organic covers by technology of MPEI NRU, which provides increasing of limiting wetting angle of surfaces to 120° and greater. Results of experimental researches of the influence of hydrophobization of impeller surfaces for high-speed pump ( n s = 330) on its characteristics is presented for the first time. Positive effect of applying hydrophobization technology to impeller surfaces in all the considered range of power-speed coefficient was generalized and estimated. It was shown that hydrophobization of impeller surfaces of centrifugal pumps provides increment to their efficiency factors within an acceptable operation range from 0.5 to 7.5%. Empiric function defining dependencies of efficiency factor increment of pump on relative supply and power-speed coefficient are suggested. Possibilities and estimation of extending acceptable operation range of a pump depending on powerspeed coefficient as a result of impeller surface hydrophobization are shown. Experimental data of comparative cavitation tests of high-speed pumps before and after hydrophobization of their impeller surfaces are generalized for the first time for considered range of power-speed coefficient values. The influence of power-speed coefficient on changing of critical net pump suction head (critical positive suction pressure) is shown. Based on existing knowledge on pumps, an attempt to validate experimentally obtained lows of changing of power and anticavitation features of centrifugal pumps after hydrophobization of their impeller surfaces is made.

  5. Runtime and Inversion Impacts on Estimation of Moisture Retention Relations by Centrifuge

    NASA Astrophysics Data System (ADS)

    Sigda, J. M.; Wilson, J. L.

    2003-12-01

    Standard laboratory methods in soil physics for measuring the moisture retention relation (drainage matric potential-volumetric moisture content relation) are each limited to only part of the moisture content range. Centrifuge systems allow intensive accurate measurements across much of the saturation range, and typically require much less time than traditional laboratory methods. An initially liquid-saturated sample is subjected to a stepwise-increasing series of angular velocities while carefully monitoring changes in liquid content. Angular velocity is held constant until the capillary and centrifugal forces equilibrate, forcing liquid flux to zero, and then a final average liquid content is noted. The procedure is repeated after increasing the angular velocity. Centrifuge measurement time is greatly reduced because the centrifugal body force gradient can far exceed the driving forces utilized in standard lab methods. Widely-used in the petroleum industry for decades, centrifuge measurement of moisture retention relations is seldom encountered in the soil physics or vadose hydrology literatures. Yet there is a need to better understand and improve the experimental methodology given the increasing number of centrifuges employed in these fields. Errors in centrifuge measurement of moisture retention relations originate from both experimental protocol and from data inversion. Like standard methods, centrifuge methods assume equilibrium conditions, and so are sensitive to errors introduced by insufficient runtimes. Unlike standard methods, centrifuge experiments require inversion of the angular velocity and average sample moisture content data to a location-specific pair of matric potential and moisture content values, The force balance causes matric potential and moisture content to vary with sample length while the sample is spinning. Numerous data inversion techniques exist, each yielding different moisture retention relations. We present analyses demonstrating

  6. Centrifugal techniques for measuring saturated hydraulic conductivity

    USGS Publications Warehouse

    Nimmo, John R.; Mello, Karen A.

    1991-01-01

    Centrifugal force is an alternative to large pressure gradients for the measurement of low values of saturated hydraulic conductivity (Ksat). With a head of water above a porous medium in a centrifuge bucket, both constant-head and falling-head measurements are practical at forces up to at least 1800 times normal gravity. Darcy's law applied to the known centrifugal potential leads to simple formulas for Ksat that are analogous to those used in the standard gravity-driven constant- and falling-head methods. Both centrifugal methods were tested on several fine-textured samples of soil and ceramic with Ksat between about 10−10 and 10−9 m/s. The results were compared to falling-head gravity measurements. The comparison shows most measurements agreeing to within 20% for a given sample, much of the variation probably resulting from run-to-run changes in sample structure. The falling-head centrifuge method proved to be especially simple in design and operation and was more accurate than the constant-head method. With modified apparatus, Ksat measurements less than 10−10 m/s should be attainable.

  7. Liquid centrifugation for nuclear waste partitioning

    SciTech Connect

    Bowman, C.D.

    1992-03-11

    The performance of liquid centrifugation for nuclear waste partitioning is examined for the Accelerator Transmutation of Waste Program currently under study at the Los Alamos National Laboratory. Centrifugation might have application for the separation of the LiF-BeF{sub 2} salt from heavier radioactive materials fission product and actinides in the separation of fission product from actinides, in the isotope separation of fission-product cesium before transmutation of the {sup 137}Cs and {sup 135}Cs, and in the removal of spallation product from the liquid lead target. It is found that useful chemical separations should be possible using existing materials for the centrifuge construction for all four cases with the actinide fraction in fission product perhaps as low as 1 part in 10{sup 7} and the fraction of {sup 137}CS in {sup 133}Cs being as low as a few parts in 10{sup 5}. A centrifuge cascade has the advantage that it can be assembled and operated as a completely closed system without a waste stream except that associated with maintenance or replacement of centrifuge components.

  8. Developing a high-resolution vehicular emission inventory by integrating an emission model and a traffic model: Part 1--Modeling fuel consumption and emissions based on speed and vehicle-specific power.

    PubMed

    Wang, Haikun; Fu, Lixin

    2010-12-01

    To improve the accuracy and applicability of vehicular emission models, this study proposes a speed and vehicle-specific power (VSP) modeling method to estimate vehicular emissions and fuel consumption using data gathered by a portable emissions monitoring system (PEMS). The PEMS data were categorized into discrete speed-VSP bins on the basis of the characteristics of vehicle driving conditions and emissions in Chinese cities. Speed-VSP modal average rates of emissions (or fuel consumption) and the time spent in the corresponding speed-VSP bins were then used to calculate the total trip emissions (or fuel consumption) and emission factors (or fuel economy) under specific average link speeds. The model approach was validated by comparing it against measured data with prediction errors within 20% for trip emissions and link-speed-based emission factors. This analysis is based on the data of light-duty gasoline vehicles in China; however, this research approach could be generalized to other vehicle fleets in other countries. This modeling method could also be coupled with traffic demand models to establish high-resolution emissions inventories and evaluate the impacts of traffic-related emission control measures.

  9. [Automatic polishing of dental prostheses. 1. Development of a centrifugal barrel finishing apparatus].

    PubMed

    Tamaki, Y; Miyazaki, T; Aoyama, N; Suzuki, E; Miyaji, T

    1990-09-01

    A centrifugal barrel finishing apparatus with a variable turn table rotational speed (250-1,000 rpm) was newly developed and barrel finishing of Ni-Cr casting plates (10 x 10 x 2 mm) was performed using alumina base chips. When using the sample with a mirror face the amount of polishing and the surface roughness increased and the surface gloss decreased with the increase in rotation speed. A high rotational speed was useful for coarse polishing and low rotational speed was useful for fine polishing. The continuous barrel polishing was trially performed using the sample prepared by the carborundum wheel under variable rotational speed. Automatic polishing to fine polishing could be done using this apparatus.

  10. Detailed stress tensor measurements in a centrifugal compressor vaneless diffuser

    SciTech Connect

    Pinarbasi, A.; Johnson, M.W.

    1996-04-01

    Detailed flow measurements have been made in the vaneless diffuser of a large low-speed centrifugal compressor using hot-wire anemometry. The three time mean velocity components and full stress tensor distributions have been determined on eight measurement plans within the diffuser. High levels of Reynolds stress result in the rapid mixing out of the blade wake. Although high levels of turbulent kinetic energy are found in the passage wake, they are not associated with strong Reynolds stresses and hence the passage wake mixes out only slowly. Low-frequency meandering of the wake position is therefore likely to be responsible for the high kinetic energy levels. The anisotropic nature of the turbulence suggests that Reynolds stress turbulence models are required for CFD modeling of diffuser flows.

  11. Novel Design for Centrifugal Countercurrent Chromatography: I. Zigzag Toroidal Column

    PubMed Central

    Yang, Yi; Aisa, Haji Akber; Ito, Yoichiro

    2009-01-01

    The toroidal coil using an equilateral triangular core has improved both retention of the stationary phase and peak resolution of the conventional toroidal coil in centrifugal countercurrent chromatography. To further improve the retention of stationary phase and peak resolution, a novel zigzag toroidal coil was designed and the performance of the system was evaluated at various flow rates. The results indicated that both retention of stationary phase and peak resolution were improved as the flow rate was decreased. Modification of the tubing by pressing at given intervals with a pair of pliers improved the peak resolution without increasing the column pressure. All these separations were performed under low column pressure indicating the separation can be further improved by increasing the column length and/or revolution speed without damaging the separation column. PMID:20046954

  12. Thirty Stage Annular Centrifugal Contactor Thermal Profile Measurements

    SciTech Connect

    David H. Meikrantz; Troy G. Garn; Jack D. Law

    2010-02-01

    A thirty stage 5 cm annular centrifugal contactor cascade has been assembled and tested to obtain thermal profiles during both ambient and heated input conditions of operation. Thermocouples were installed on every stage as well as feed inputs and Real-time data was taken during experiments lasting from two to eight hours at total flow rates of 0.5 to 1.4 liters per minute. Ambient temperature profile results show that only a small amount of heat is generated by the mechanical energy of the contactors. Steady state temperature profiles mimic the ambient temperature of the lab but are higher toward the middle of the cascade. Heated inlet solutions gave temperature profiles with smaller temperature gradients, more driven by the temperature of the inlet solutions than ambient lab temperature. Temperature effects of solution mixing, even at rotor speeds of 4000 rpm, were not measurable.

  13. Characterization of a centrifugal pump in He II

    NASA Technical Reports Server (NTRS)

    Weisend, J. G., II; Van Sciver, S. W.

    1988-01-01

    As part of an effort to determine the feasibility of helium transfer in space, a centrifugal pump was tested in He II at a variety of flow rates, pump speeds, and fluid temperatures. The pump, which has a straight bladed impeller 6.86 cm in diameter, generated a maximum pressure rise of 15 kPa and a maximum flow rate of 22 g/s for the conditions of the test. Pump performance seems to be independent of fluid temperature and is in good agreement with the values predicted by the manufacturer. Over the range of flow coefficients, the measured maximum efficiency is around 50 percent. Cavitation is observed in the pump and is thought to be highly dependent on the local heating of the helium in the pump. Preliminary measurements of the noise spectra of the pump suggest a possible mechanism to predict the onset of cavitation.

  14. Characterization of a centrifugal pump in He II

    NASA Technical Reports Server (NTRS)

    Weisend, J. G., II; Van Sciver, S. W.

    1988-01-01

    As part of an effort to determine the feasibility of helium transfer in space, a centrifugal pump was tested in He II at a variety of flow rates, pump speeds, and fluid temperatures. The pump, which has a straight bladed impeller 6.86 cm in diameter, generated a maximum pressure rise of 15 kPa and a maximum flow rate of 22 g/s for the conditions of the test. Pump performance seems to be independent of fluid temperature and is in good agreement with the values predicted by the manufacturer. Over the range of flow coefficients, the measured maximum efficiency is around 50 percent. Cavitation is observed in the pump and is thought to be highly dependent on the local heating of the helium in the pump. Preliminary measurements of the noise spectra of the pump suggest a possible mechanism to predict the onset of cavitation.

  15. Centrifugal compressors for automotive air conditioners -- Component design

    SciTech Connect

    Yun, H.; Smith, J.L. Jr.

    1996-12-31

    The application of a novel, electric motor-driven, variable-speed centrifugal compressor for automotive air conditioners has been investigated. For the feasibility analysis, a configuration design has been performed. It includes refrigerant selection, thermodynamic cycle analysis, compressor aerodynamic design, and mechanical layout of the integrated motor-compressor structure. Both the motor constraints (provided by the Laboratory for Electromagnetic and Electronic Systems at M.I.T.) and the compressor constraints were considered for the configuration design. The result is an inter-cooled two-stage compression system using R123 as the refrigerant. The inter-cooling is achieved by feeding back a small fraction of the condenser liquid into the return channel between the first and the second stage through the electric motor. At the design condition, the pressure ratio is 3.2 for the first stage and 1.9 for the second stage. The design rotational speed is 75,000 rpm, and the maximum cooling capacity is 5,275 Watts. High efficiency is expected by varying the compressor speed to match the required cooling load at each instant.

  16. A rapid prototyping technique for valves and filters in centrifugal microfluidic devices.

    PubMed

    LaCroix-Fralish, Angela; Templeton, Erin J; Salin, Eric D; Skinner, Cameron D

    2009-11-07

    Using short lengths of fused silica capillary tubing embedded in the disk, a system for valving and filtering samples on centrifugal microfluidic devices has been designed and implemented. Sedimentation of turbid samples and transfer of the clear supernatant was also accomplished. Also demonstrated is the transfer of the liquid through a second capillary valve to the final reservoir. By controlling rotational speed, sedimentation and multiple step valving operations are readily implemented and easily prototyped.

  17. Progress of High Efficiency Centrifugal Compressor Simulations Using TURBO

    NASA Technical Reports Server (NTRS)

    Kulkarni, Sameer; Beach, Timothy A.

    2017-01-01

    Three-dimensional, time-accurate, and phase-lagged computational fluid dynamics (CFD) simulations of the High Efficiency Centrifugal Compressor (HECC) stage were generated using the TURBO solver. Changes to the TURBO Parallel Version 4 source code were made in order to properly model the no-slip boundary condition along the spinning hub region for centrifugal impellers. A startup procedure was developed to generate a converged flow field in TURBO. This procedure initialized computations on a coarsened mesh generated by the Turbomachinery Gridding System (TGS) and relied on a method of systematically increasing wheel speed and backpressure. Baseline design-speed TURBO results generally overpredicted total pressure ratio, adiabatic efficiency, and the choking flow rate of the HECC stage as compared with the design-intent CFD results of Code Leo. Including diffuser fillet geometry in the TURBO computation resulted in a 0.6 percent reduction in the choking flow rate and led to a better match with design-intent CFD. Diffuser fillets reduced annulus cross-sectional area but also reduced corner separation, and thus blockage, in the diffuser passage. It was found that the TURBO computations are somewhat insensitive to inlet total pressure changing from the TURBO default inlet pressure of 14.7 pounds per square inch (101.35 kilopascals) down to 11.0 pounds per square inch (75.83 kilopascals), the inlet pressure of the component test. Off-design tip clearance was modeled in TURBO in two computations: one in which the blade tip geometry was trimmed by 12 mils (0.3048 millimeters), and another in which the hub flow path was moved to reflect a 12-mil axial shift in the impeller hub, creating a step at the hub. The one-dimensional results of these two computations indicate non-negligible differences between the two modeling approaches.

  18. Liquid egg white pasteurization using a centrifugal UV irradiator.

    PubMed

    Geveke, David J; Torres, Daniel

    2013-03-01

    Studies are limited on UV nonthermal pasteurization of liquid egg white (LEW). The objective of this study was to inactivate Escherichia coli using a UV irradiator that centrifugally formed a thin film of LEW on the inside of a rotating cylinder. The LEW was inoculated with E. coli K12 to approximately 8 log cfu/ml and was processed at the following conditions: UV intensity 1.5 to 9.0 mW/cm²; cylinder rotational speed 450 to 750 RPM, cylinder inclination angle 15° to 45°, and flow rate 300 to 900 ml/min, and treatment time 1.1 to 3.2s. Appropriate dilutions of the samples were pourplated with tryptic soy agar (TSA). Sublethal injury was determined using TSA+4% NaCl. The regrowth of surviving E. coli during refrigerated storage for 28 days was investigated. The electrical energy of the UV process was also determined. The results demonstrated that UV processing of LEW at a dose of 29 mJ/cm² at 10°C reduced E. coli by 5 log cfu/ml. Inactivation significantly increased with increasing UV dose and decreasing flow rate. The results at cylinder inclination angles of 30° and 45° were similar and were significantly better than those at 15°. The cylinder rotational speed had no significant effect on inactivation. The occurrence of sublethal injury was detected. Storage of UV processed LEW at 4° and 10°C for 21 days further reduced the population of E. coli to approximately 1 log cfu/ml where it remained for an additional 7 days. The UV energy applied to the LEW to obtain a 5 log reduction of E. coli was 3.9 J/ml. These results suggest that LEW may be efficiently pasteurized, albeit at low flow rates, using a nonthermal UV device that centrifugally forms a thin film.

  19. Possible segregation caused by centrifugal titanium casting.

    PubMed

    Watanabe, K; Okawa, S; Kanatani, M; Nakano, S; Miyakawa, O; Kobayashi, M

    1996-12-01

    The possibility of the segregation under solidification process using a centrifugal casting machine was investigated using an electron probe microanalyzer with elemental distribution map, line analysis and quantitative analysis. When a very small quantity of platinum was added to local molten titanium during the casting process, macroscopic segregation was observed under conditions of density difference of 0.1 g/cm3 at the most, confirming that the centrifugal force of the casting machine is extremely strong. When a Ti-6Al-4V alloy was cast, however, no macroscopic segregation was observed. The centrifugal force of the casting machine examined in the present study hardly results in the body-force segregation in this titanium alloy.

  20. Effects of chronic centrifugation on mice

    NASA Technical Reports Server (NTRS)

    Janer, L.; Duke, J.

    1984-01-01

    Previous studies have shown that exposure to excess gravity in vitro alters the developmental sequence in embryonic mouse limbs and palates (Duke, Janer and Campbell, 1984; Duke, 1983). The effects of excess gravity on in vivo mammalian development was investigated using a small animal centrifuge. Four-week old female mice exposed to excess gravities of 1.8-3.5 G for eight weeks weighed significantly less than controls. Mice were mated after five weeks of adaptation to excess G, and sacrificed either at gestational day 12 or 18. There were fewer pregnancies in the centrifuged group (4/36) than in controls (9/31), and crown rump lengths (CRL) of embryos developing in the centrifuge were less than CRLs of 1-G embryos. These results show that although immersed in amniotic fluid, embryos are responsive to Delta-G.

  1. Effects of chronic centrifugation on mice

    NASA Technical Reports Server (NTRS)

    Janer, L.; Duke, J.

    1984-01-01

    Previous studies have shown that exposure to excess gravity in vitro alters the developmental sequence in embryonic mouse limbs and palates (Duke, Janer and Campbell, 1984; Duke, 1983). The effects of excess gravity on in vivo mammalian development was investigated using a small animal centrifuge. Four-week old female mice exposed to excess gravities of 1.8-3.5 G for eight weeks weighed significantly less than controls. Mice were mated after five weeks of adaptation to excess G, and sacrificed either at gestational day 12 or 18. There were fewer pregnancies in the centrifuged group (4/36) than in controls (9/31), and crown rump lengths (CRL) of embryos developing in the centrifuge were less than CRLs of 1-G embryos. These results show that although immersed in amniotic fluid, embryos are responsive to Delta-G.

  2. Neuro-Motor Responses to Daily Centrifugation in Bed-Rested Subjects

    NASA Technical Reports Server (NTRS)

    Reschke, Millard F.; Somers, Jeffery T.; Krnavek, Jody; Fisher, Elizibeth; Ford, George; Paloski, William H.

    2007-01-01

    It is well known from numerous space flight studies that exposure to micro-g produces both morphological and neural adaptations in the major postural muscles. However, the characteristics and mechanism of these changes, particularly when it may involve the central nervous system are not defined. Furthermore, it is not known what role unloading of the muscular system may have on central changes in sensorimotor function or if centrifugation along the +Gz direction (long body axis) can mitigate both the peripheral changes in muscle function and modification of the central changes in sensorimotor adaptation to the near weightless environment of space flight. The purpose of this specific effort was, therefore, to investigate the efficacy of artificial gravity (AG) as a method for maintaining sensorimotor function in micro-g. Eight male subjects were exposed to daily 1 hr centrifugation during a 21 day 6 degree head-down bed rest study. Seven controls were placed on the centrifuge without rotation. The radius and angular velocity of the centrifuge were adjusted such that each subject experienced a centripetal acceleration of 2.5g at the feet, and approximately 1.0g at the heart. Both the tendon (MSR) and functional stretch reflexes (FSR) were collected using an 80 lb. ft. servomotor controlled via position feedback to provide a dorsiflexion step input to elicit the MSR, and the same step input with a built in 3 sec hold to evoke the FSR. EMG data were obtained from the triceps surae. Supplementary torque, velocity and position data were collected with the EMG responses. All data were digitized and sampled at 4 kHz. Only the MSR data has been analyzed at this time, and preliminary results suggest that those subjects exposed to active centrifugation (treatment group) show only minor changes in MSR peak latency times, either as a function of time spent in bed rest or exposure to centrifugation, while the control subjects show delays in the MSR peak latencies that are

  3. Neuro-Motor Responses to Daily Centrifugation in Bed-Rested Subjects

    NASA Technical Reports Server (NTRS)

    Reschke, Millard F.; Somers, Jeffery T.; Krnavek, Jody; Fisher, Elizibeth; Ford, George; Paloski, William H.

    2007-01-01

    It is well known from numerous space flight studies that exposure to micro-g produces both morphological and neural adaptations in the major postural muscles. However, the characteristics and mechanism of these changes, particularly when it may involve the central nervous system are not defined. Furthermore, it is not known what role unloading of the muscular system may have on central changes in sensorimotor function or if centrifugation along the +Gz direction (long body axis) can mitigate both the peripheral changes in muscle function and modification of the central changes in sensorimotor adaptation to the near weightless environment of space flight. The purpose of this specific effort was, therefore, to investigate the efficacy of artificial gravity (AG) as a method for maintaining sensorimotor function in micro-g. Eight male subjects were exposed to daily 1 hr centrifugation during a 21 day 6 degree head-down bed rest study. Seven controls were placed on the centrifuge without rotation. The radius and angular velocity of the centrifuge were adjusted such that each subject experienced a centripetal acceleration of 2.5g at the feet, and approximately 1.0g at the heart. Both the tendon (MSR) and functional stretch reflexes (FSR) were collected using an 80 lb. ft. servomotor controlled via position feedback to provide a dorsiflexion step input to elicit the MSR, and the same step input with a built in 3 sec hold to evoke the FSR. EMG data were obtained from the triceps surae. Supplementary torque, velocity and position data were collected with the EMG responses. All data were digitized and sampled at 4 kHz. Only the MSR data has been analyzed at this time, and preliminary results suggest that those subjects exposed to active centrifugation (treatment group) show only minor changes in MSR peak latency times, either as a function of time spent in bed rest or exposure to centrifugation, while the control subjects show delays in the MSR peak latencies that are

  4. 26. RW Meyer Sugar Mill: 18761889. Centrifugals, 1879, 1881. Manufacturer, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. RW Meyer Sugar Mill: 1876-1889. Centrifugals, 1879, 1881. Manufacturer, unknown. Supplied by Honolulu Ironworks, Honolulu, Hawaii, 1879, 1881. View: Historical view, 1934, from T. T. Waterman collection, Hawaiian Sugar Planters' Association. Once the molasses was separated from the sugar crystals it flowed through the spouts in the base of the centrifugals. The centrifugals' pulleys can be seen underneath the centrifugal. The centrifugal on the right has been reinforced with seven metal bands. The handles for the clutch mechanism are located above the centrifugal. - R. W. Meyer Sugar Mill, State Route 47, Kualapuu, Maui County, HI

  5. Compact type-I coil planet centrifuge for counter-current chromatography

    PubMed Central

    Yang, Yi; Gu, Dongyu; Liu, Yongqiang; Aisa, Haji Akber; Ito, Yoichiro

    2009-01-01

    A compact type-I coil planet centrifuge has been developed for performing counter-current chromatography. It has a revolution radius of 10 cm and a column holder height of 5 cm compared with 37 cm and 50 cm in the original prototype, respectively. The reduction in the revolution radius and column length permits application of higher revolution speed and more stable balancing of the rotor which leads us to learn more about its performance and the future potential of type-I coil planet centrifuge. The chromatographic performance of this apparatus was evaluated in terms of retention of the stationary phase (Sf), peak resolution (Rs), theoretical plate (N) and peak retention time (tR). The results of the experiment indicated that increasing the revolution speed slightly improved both the retention of the stationary phase and the peak resolution while the separation time is remarkably shortened to yield an excellent peak resolution at a revolution speed of 800 rpm. With a 12 ml capacity coiled column, DNP-glu, DNP-β-ala and DNP-ala were resolved at Rs of 2.75 and 2.16 within 90 min at a flow rate of 0.4 ml/min. We believe that the compact type-I coil planet centrifuge has a high analytical potential. PMID:20060979

  6. Compact type-I coil planet centrifuge for counter-current chromatography.

    PubMed

    Yang, Yi; Gu, Dongyu; Liu, Yongqiang; Aisa, Haji Akber; Ito, Yoichiro

    2010-02-19

    A compact type-I coil planet centrifuge has been developed for performing counter-current chromatography. It has a revolution radius of 10 cm and a column holder height of 5 cm compared with 37 and 50 cm in the original prototype, respectively. The reduction in the revolution radius and column length permits application of higher revolution speed and more stable balancing of the rotor which leads us to learn more about its performance and the future potential of type-I coil planet centrifuge. The chromatographic performance of this apparatus was evaluated in terms of retention of the stationary phase (S(f)), peak resolution (R(s)), theoretical plate (N) and peak retention time (t(R)). The results of the experiment indicated that increasing the revolution speed slightly improved both the retention of the stationary phase and the peak resolution while the separation time is remarkably shortened to yield an excellent peak resolution at a revolution speed of 800 rpm. With a 12 ml capacity coiled column, DNP-DL-glu, DNP-beta-ala and DNP-l-ala were resolved at R(s) of 2.75 and 2.16 within 90 min at a flow rate of 0.4 ml/min. We believe that the compact type-I coil planet centrifuge has a high analytical potential. Published by Elsevier B.V.

  7. Development of an autoflow cruise control system for a centrifugal pump.

    PubMed

    Nishida, H; Beppu, T; Nakajima, M; Nishinaka, T; Nakatani, H; Ihashi, K; Katsumata, T; Kitamura, M; Aomi, S; Endo, M

    1995-07-01

    To improve the ease of driving a centrifugal pump that is afterload dependent, we have developed an automatic flow control system for the Terumo Capiox centrifugal pump system. This system consists of an autoflow cruise control system with a safety cutoff. The Capiox Pump Console 3000 was controlled by a personal computer through a serial communication line. In the usual manual mode, the motor speed knob works as a pump speed control, and in the autoflow mode, the same knob works as a blood flow rate control. After selecting and obtaining the desired flow rate, the mode was changed from manual to autoflow mode. In the autoflow mode, the computer compares the desired flow rate with the actual flow measured by an ultrasonic Doppler flowmeter and adjusts the motor rotational speed accordingly. During both in vivo and in vitro testing, this autoflow mode was able to return the changed flow that was disrupted by either clamping and declamping of the tubing or by the bolus injection of a vasomotor drug to the selected flow rate within 10 s without any significant fluctuation. In conclusion, the newly developed computer controlled autoflow system was able to produce a reliable and effective flow regulation for a centrifugal pump.

  8. A real-time dynamic imaging system for centrifugal microflow platforms

    NASA Astrophysics Data System (ADS)

    Chang, Hsing-Cheng; Tsou, Chingfu; Lai, Chi-Chih; Wun, Guo-Hong

    2008-07-01

    Based on the operational concept of quasi-static state and optoelectronic measurement technology, this research develops a real-time dynamic imaging system for centrifugal microfluidic platforms. Unlike the conventional centrifugal inspection system, which can only be used for examination of the final steady stage in microflow analysis, the developed system with a multi-speed controller and object tracking design is fabricated with low cost to recognize dynamic microflow patterns for different kinds of compact disc-type centrifugal microstructures. The characteristics of rotational control efficiency and image acquisition quality are obtained from fluidic microvalve experiments that are achieved in measuring microflow dynamic responses and in visualizing transient microflow patterns. A man-machine interface was connected with a computer to perform the control and alignment adjustments to catch exact image data for following analysis. The rotation stability of the system has been evaluated, and the rotation speed up to 4500 rpm with vertical vibration less than ±0.2 mm is achieved measured at radial distance of 5 cm. The image acquisition is transferred via USB 2.0 at a speed of up to 30 images per second to the display and memory module.

  9. Group Balance Training Specifically Designed for Individuals With Alzheimer Disease: Impact on Berg Balance Scale, Timed Up and Go, Gait Speed, and Mini-Mental Status Examination.

    PubMed

    Ries, Julie D; Hutson, Janet; Maralit, Leslie A; Brown, Megan B

    2015-01-01

    Individuals with Alzheimer disease (IwAD) experience more frequent and more injurious falls than their cognitively intact peers. Evidence of balance and gait dysfunction is observed earlier in the course of Alzheimer disease (AD) than once believed. Balance training has been demonstrated to be effective in improving balance and decreasing falls in cognitively intact older adults but is not well studied in IwAD. This study was designed to analyze the effects of a group balance training program on balance and falls in IwAD. The program was developed specifically for IwAD, with explicit guidelines for communication/interaction and deliberate structure of training sessions catered to the motor learning needs of IwAD. This prospective, quasi-experimental, pretest-posttest design study describes the effects of a balance training program for a cohort of IwAD. Thirty IwAD were recruited from 3 adult day health centers; 22 completed at least 1 posttest session. Participants were tested with Berg Balance Scale (BBS), Timed Up and Go (TUG), Self-Selected Gait Speed (SSGS), Fast Gait Speed (FGS), and Mini-Mental Status Examination (MMSE) immediately before and after the 3-month intervention and again 3 months later. Group training was held at the adult day health centers for 45 minutes, twice per week. Sessions were characterized by massed, constant, and blocked practice of functional, relevant activities with considerable repetition. Ratio of participant to staff member never exceeded 3:1. Physical therapist staff members assured that participants were up on their feet the majority of each session and were individually challenged as much as possible. Repeated-measures analysis of variance (ANOVA) for BBS was significant (F = 15.04; df = 1.67/28.40; P = .000) with post hoc tests, revealing improvement between pretest and immediate posttest (P = .000) and decline in performance between immediate and 3-month posttest (P = .012). Repeated-measures ANOVA posttest for MMSE was

  10. Effects of Centrifuge Diameter and Operation on Rodent Adaptation to Chronic Centrifugation

    NASA Technical Reports Server (NTRS)

    Fuller, Charles A.

    1997-01-01

    This study examined the responses of rats to centrifugation in a constant acceleration field (1.5 G). Centrifuge diameter (1.8m, 2.5m or 6.0m) and schedule of operation (Daily or weekly stop) varied between groups. Body mass, food consumption, water consumption and neurovestibular function were measured weekly. Body temperature and activity were continuously monitored using telemetry. A subset of subjects were videotaped (50 minutes per day) to allow for movement analysis. Exposure to a hyperdynamic field of this magnitude did cause the expected depression in the physiological variables monitored. Recovery was accomplished within a relatively rapid time frame; all variables returned to precentrifugation levels. In general, the magnitudes of the changes and the rate of recovery were similar at different centrifuge diameters and stopping frequency. There were cases, however, in which the magnitude of the response and/or the rate of recovery to a new steady-state were altered as a result of centrifuge diameter. In summary, these results indicate that stopping frequency has little, if any, effect on adaptation to chronic centrifugation. However, the angular velocity (omega), and therefore centrifuge diameter is an important consideration in the adaptation of an organism to chronic centrifugation.

  11. Effects of Centrifuge Diameter and Operation on Rodent Adaptation to Chronic Centrifugation

    NASA Technical Reports Server (NTRS)

    Fuller, Charles A.

    1992-01-01

    This study examined the responses of rats to centrifugation in a constant acceleration field (1.5 G). Centrifuge diameter (1.8m, 2.5m or 6.0m) and schedule of operation (Daily or weekly stop) varied between groups. Body mass, food consumption, water consumption and neurovestibular function were measured weekly. Body temperature and activity were continuously monitored using telemetry. A subset of subjects were videotaped (50 minutes per day) to allow for movement analysis. Exposure to a hyperdynamic field of this magnitude did cause the expected depression in the physiological variables monitored. Recovery was accomplished within a relatively rapid time frame; all variables returned to precentrifugation levels. In general, the magnitudes of the changes and the rate of recovery were similar at different centrifuge diameters and stopping frequency. There were cases, however, in which the magnitude of the response and/or the rate of recovery to a new steady-state were altered as a result of centrifuge diameter. In summary, these results indicate that stopping frequency has little, if any, effect on adaptation to chronic centrifugation. However, the angular velocity (omega), and therefore centrifuge diameter is an important consideration in the adaptation of an organism to chronic centrifugation.

  12. A network application for modeling a centrifugal compressor performance map

    NASA Astrophysics Data System (ADS)

    Nikiforov, A.; Popova, D.; Soldatova, K.

    2017-08-01

    The approximation of aerodynamic performance of a centrifugal compressor stage and vaneless diffuser by neural networks is presented. Advantages, difficulties and specific features of the method are described. An example of a neural network and its structure is shown. The performances in terms of efficiency, pressure ratio and work coefficient of 39 model stages within the range of flow coefficient from 0.01 to 0.08 were modeled with mean squared error 1.5 %. In addition, the loss and friction coefficients of vaneless diffusers of relative widths 0.014-0.10 are modeled with mean squared error 2.45 %.

  13. Critique of ``Centrifugal Gas Compression Cycle''

    NASA Astrophysics Data System (ADS)

    Wheeler, John C.

    2002-11-01

    In a paper in this volume, "Centrifugal Gas Compression Cycle," a thermodynamic cycle is introduced that the author claims will convert heat from a reservoir at fixed temperature entirely into work. His analysis suffers from a fatal flaw that invalidates his conclusion, namely, a failure to correctly account for the work and heat flux involved in an isothermal centrifugal compression of a gas. We give a correct accounting here that demonstrates that this process is not simultaneously isothermal and adiabatic, as the author claims, but rather involves the evolution of heat. This invalidates the author's analysis.

  14. Centrifuge for separating helium from natural gas

    SciTech Connect

    Theyse, F.H.; Kelling, F.E.T.

    1980-01-08

    Ultra Centrifuge Nederland N.V.'s improved centrifuge for separating helium from natural gas comprises a hollow cylindrical rotor, designated as a separating drum, within a stationary housing. Natural gas liquids that condense under pressure in the separating drum pass through openings in the drum into the space between the drum and housing. In this space, a series of openings, or throttling restrictors, allows the liquids to expand and return to gas. The gaseous component that does not liquefy in the drum remains separate for drawing off.

  15. Wave-Driven Rotation In Centrifugal Mirrors

    SciTech Connect

    Abraham J. Fetterman and Nathaniel J. Fisch

    2011-03-28

    Centrifugal mirrors use supersonic rotation to provide axial confinement and enhanced stability. Usually the rotation is produced using electrodes, but these electrodes have limited the rotation to the Alfven critical ionization velocity, which is too slow to be useful for fusion. Instead, the rotation could be produced using radio frequency waves. A fixed azimuthal ripple is a simple and efficient wave that could produce rotation by harnessing alpha particle energy. This is an extension of the alpha channeling effect. The alpha particle power and efficiency in a simulated devices is sufficient to produce rotation without external energy input. By eliminating the need for electrodes, this opens new opportunities for centrifugal traps.

  16. Detection methods for centrifugal microfluidic platforms.

    PubMed

    Burger, Robert; Amato, Letizia; Boisen, Anja

    2016-02-15

    Centrifugal microfluidics has attracted much interest from academia as well as industry, since it potentially offers solutions for affordable, user-friendly and portable biosensing. A wide range of so-called fluidic unit operations, e.g. mixing, metering, liquid routing, and particle separation, have been developed and allow automation and integration of complex assay protocols in lab-on-a-disc systems. Besides liquid handling, the detection strategy for reading out the assay is crucial for developing a fully integrated system. In this review, we focus on biosensors and readout methods for the centrifugal microfluidics platform and cover optical as well as mechanical and electrical detection principles.

  17. Numerical comparisons of the performance of a hydraulic coupling with different pump rotational speeds

    NASA Astrophysics Data System (ADS)

    Luo, Y.; Feng, L. H.; Liu, S. H.; Chen, T. J.; Fan, H. G.

    2013-12-01

    A hydraulic coupling is a hydrodynamic device for transmitting rotating mechanical power. It is widely used in the machinery industry because of its advantages of high energy transmission efficiency, shock absorption and good adaptability, etc. In this paper, SIMPLEC algorithm and SST k-ω turbulence model were employed to simulate the steady state flows at operating conditions of two different rotational speeds (3000r/min and 7500 r/min) of the pump of a specified hydraulic coupling model. The results indicate the existence of similarity in the distributions of the flow fields between the two speeds, but the efficiency at the optimum condition is larger with higher rotational speed. It is concluded that the similarity principle of the efficiency of the hydraulic couplings does not apply in this case due to the relatively high rotating speed and small geometric specifications. It is also shown that the radially stratified pressure distribution on the torus section becomes more obvious with larger speed ratios, since the centrifugal movement plays more dominant roles over the circulating movement in these situations. When the speed ratio is small, with the completion of the circulating flow, the pressure distribution presents in a more circular pattern around the neutral zone of the torus section.

  18. Density-gradient-assisted centrifugal microfluidics: an approach to continuous-mode particle separation.

    PubMed

    Ukita, Yoshiaki; Oguro, Takayuki; Takamura, Yuzuru

    2017-06-01

    Centrifugal microfluidics has been recognized as a promising pumping method in microfluidics because of its simplicity, easiness of automation, and parallel processing. However, the patterning of stripe flow in centrifugal microfluidics is challenging because a fluid is significantly affected by the Coriolis force, which produces an intrinsic secondary flow. This paper reports a technical and design strategy for centrifugal microfluidics called "density-gradient-assisted centrifugal microfluidics." The flow behavior is observed with the presence of a density gradient and without a density gradient in two concentrically traveling phase flows. As a result, clear stripe flow pattern is observed with a density difference of 0.05 g/cm(3) between water and a percoll solution at a flow rate of 11.8 μl/s (7 ml/10 min) and spinning speed of 3000 rpm. In contrast, without a density gradient, it is necessary to reduce the flow rate and spinning speed to 0.1 μl/s and 1000 rpm, respectively. This paper also presents the use of a density gradient to assist in focusing resin (polystyrene) particles on the boundary of a stripe flow pattern that consists of water and percoll with different densities. Moreover, the density-based separation and sorting of particles in a mixed particle suspension is demonstrated. Polystyrene is selectively focused on the boundary, but silica particles are separated from the focused trajectory due to a difference in density. The separated particles are continuously sorted into different reservoirs with polystyrene and silica separation efficiencies of 96.5% and 98.5%, respectively. The pumping, stripe flow pattern formation, particle concentration, and sorting are simultaneously realized by applying a density gradient and centrifugal force. Therefore, this principle can realize a very simple technique for label-free particle separation by just spinning a disk device and can be applied in other applications by the use of the density

  19. Invited Review Article: Review of centrifugal microfluidic and bio-optical disks

    NASA Astrophysics Data System (ADS)

    Nolte, David D.

    2009-10-01

    Spinning biodisks have advantages that make them attractive for specialized biochip applications. The two main classes of spinning biodisks are microfluidic disks and bio-optical compact disks (BioCD). Microfluidic biodisks take advantage of noninertial pumping for lab-on-a-chip devices using noninertial valves and switches under centrifugal and Coriolis forces to distribute fluids about the disks. BioCDs use spinning-disk interferometry, under the condition of common-path phase quadrature, to perform interferometric label-free detection of molecular recognition and binding. The optical detection of bound molecules on a disk is facilitated by rapid spinning that enables high-speed repetitive sampling to eliminate 1/f noise through common-mode rejection of intensity fluctuations and extensive signal averaging. Multiple quadrature classes have been developed, such as microdiffraction, in-line, phase contrast, and holographic adaptive optics. Thin molecular films are detected through the surface dipole density with a surface height sensitivity for the detection of protein spots that is approximately 1 pm. This sensitivity easily resolves a submonolayer of solid-support immobilized antibodies and their antigen targets. Fluorescence and light scattering provide additional optical detection techniques on spinning disks. Immunoassays have been applied to haptoglobin using protein A/G immobilization of antibodies and to prostate specific antigen. Small protein spots enable scalability to many spots per disk for high-throughput and highly multiplexed immonoassays.

  20. Centrifugal and Axial Pump Design and Off-Design Performance Prediction

    NASA Technical Reports Server (NTRS)

    Veres, Joseph P.

    1995-01-01

    A meanline pump-flow modeling method has been developed to provide a fast capability for modeling pumps of cryogenic rocket engines. Based on this method, a meanline pump-flow code PUMPA was written that can predict the performance of pumps at off-design operating conditions, given the loss of the diffusion system at the design point. The design-point rotor efficiency and slip factors are obtained from empirical correlations to rotor-specific speed and geometry. The pump code can model axial, inducer, mixed-flow, and centrifugal pumps and can model multistage pumps in series. The rapid input setup and computer run time for this meanline pump flow code make it an effective analysis and conceptual design tool. The map-generation capabilities of the code provide the information needed for interfacing with a rocket engine system modeling code. The off-design and multistage modeling capabilities of PUMPA permit the user to do parametric design space exploration of candidate pump configurations and to provide head-flow maps for engine system evaluation.

  1. Development of small centrifugal pumps for an electric propellant pump system

    NASA Astrophysics Data System (ADS)

    Johnsson, Göran; Bigert, Mikael

    Small centrifugal pumps with low specific speeds have been designed, manufactured and performance tested at Volvo Flygmotor AB under a contract from the European Space Agency (ESA) over the period mid-1985 to mid-1988. The development of the pumps is a part of the work carried out to develop an Electric Propellant Pump System (EPPS) for the storable propellant monomethyl hydrazine (MMH) and nitrogen tetraoxide (NTO). Supporting technology development has been funded by the Swedish Delegation for Space Activities (DFR) and Swedish Space Corporation (SSC) together with Volvo Flygmotor. The main advantages of a typical EPPS communication satellite application are weight and volume reduction of the propellant system compared with a pressure-fed system. Active engine mixture ratio control and improved propellant utilization are also possible. Refuelling in space is another potential application where EPPS can be used. The development work was focused on communication satellite apogee propulsion and used the MBB 3 kN engine as reference. This paper presents the pump design and analyses and the results from the test campaigns of three different pump configurations, carried out with water as test liquid. The head rise, efficiency and suction performance together with other characteristics are also given. The planned next development step is to demonstrate pump performance in the propellants and primarily in NTO. The step is funded by (DFR)/(SSC) together with Volvo Flygmotor.

  2. Experimental on-stream elimination of resonant whirl in a large centrifugal compressor

    NASA Technical Reports Server (NTRS)

    Bhat, G. I.; Eierman, R. G.

    1984-01-01

    Resonant whirl condition during operation of a multi-stage centrifugal compressor at higher than anticipated speeds and loads was reported. The condition was diagnosed by a large scale computerized Machinery Condition Monitoring System (MACMOS). This computerized system verified that the predominant subsynchronous whirl frequency locked in on the first resonant frequency of the compressor rotor and did not vary with compressor speed. Compressor stability calculations showed the rotor system had excessive hearing stiffness and inadequate effective damping. An optimum bearing design which was developed to minimize the unbalance response and to maximize the stability threshold is presented.

  3. Rotary Speed Sensor for Antilocking Brakes

    NASA Technical Reports Server (NTRS)

    Berdahl, C. M.

    1986-01-01

    Sensor based on fluidic principles produces negative pressure approximately proportional to rotational speed. Sensor developed as part of antilocking brake system for motorcycles. Uses inlet pressure rather than outlet pressure as braking-control signal, eliminating pressure pulsations caused by pump vanes and ensuring low-noise signal. Sensor is centrifugal air pump turned by one of motorcycle wheels. Air enters pump through orifice plates, and suction taken off through port in pump inlet plenum.

  4. Astronaut Virgil Grissom - Training Prep - Centrifuge - Johnsonville, PA

    NASA Image and Video Library

    1959-01-01

    B59-00586 (1959) --- Astronaut Virgil (Gus) Grissom is seen preparing for training in the centrifuge at Johnsville. A Navy corpsman attaches sensors to Grissom to monitor his body's reaction to the centrifuge. Photo credit: NASA

  5. Research centrifuge accommodations on Space Station Freedom

    NASA Technical Reports Server (NTRS)

    Arno, Roger D.; Horkachuk, Michael J.

    1990-01-01

    Life sciences research using plants and animals on the Space Station Freedom requires the ability to maintain live subjects in a safe and low stress environment for long durations at microgravity and at one g. The need for a centrifuge to achieve these accelerations is evident. Programmatic, technical, and cost considerations currently favor a 2.5 meter diameter centrifuge located either in the end cone of a Space Station Freedom node or in a separate module. A centrifuge facility could support a mix of rodent, plant, and small primate habitats. An automated cage extractor could be used to remove modular habitats in pairs without stopping the main rotor, minimizing the disruption to experiment protocols. The accommodation of such a centrifuge facility on the Space Station represents a significant demand on the crew time, power, data, volume, and logistics capability. It will contribute to a better understanding of the effects of space flight on humans, an understanding of plant growth in space for the eventual production of food, and an understanding of the role of gravity in biological processes.

  6. Evaluation of an improved centrifugal casting machine.

    PubMed

    Donovan, T E; White, L E

    1985-05-01

    A Type III gold alloy, a silver-palladium alloy, and a base metal alloy were cast in two different centrifugal casting machines. With the number of complete cast mesh squares as an indicator of castability, the Airspin casting machine produced superior castings with all three alloys. The base metal alloy produced the greatest number of complete squares with both casting machines.

  7. Pressure distribution in centrifugal dental casting.

    PubMed

    Nielsen, J P

    1978-02-01

    Equations are developed for liquid metal pressure in centrifugal dental casting, given the instantaneous rotational velocity, density, and certain dimensions of the casting machine and casting pattern. A "reference parabola" is introduced making the fluid pressure concept more understandable. A specially designed specimen demonstrates experimentally the reference parabola at freezing.

  8. 21 CFR 864.5350 - Microsedimentation centrifuge.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Microsedimentation centrifuge. 864.5350 Section 864.5350 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Automated and Semi-Automated Hematology...

  9. Centrifuge in space fluid flow visualization experiment

    NASA Technical Reports Server (NTRS)

    Arnold, William A.; Wilcox, William R.; Regel, Liya L.; Dunbar, Bonnie J.

    1993-01-01

    A prototype flow visualization system is constructed to examine buoyancy driven flows during centrifugation in space. An axial density gradient is formed by imposing a thermal gradient between the two ends of the test cell. Numerical computations for this geometry showed that the Prandtl number plays a limited part in determining the flow.

  10. Mass Transfer in 12-CM Centrifugal Contactors

    SciTech Connect

    Chesna, J.C.

    2001-06-26

    One eight-stage unit (8-pack) of centrifugal contactors was tested in both extraction and stripping modes. Efficiencies approaching 100 percent were obtained in both modes. The contactors were operated successfully at a wide range of combined flow rates, including the HEF conditions. This report discusses the results of that test.

  11. Centrifugal Pump Experiment for Chemical Engineering Undergraduates

    ERIC Educational Resources Information Center

    Vanderslice, Nicholas; Oberto, Richard; Marrero, Thomas R.

    2012-01-01

    The purpose of this paper is to describe a Centrifugal Pump Experiment that provided an experiential learning experience to chemical engineering undergraduates at the University of Missouri in the spring of 2010 in the Unit Operations Laboratory course. Lab equipment was used by senior students with computer-based data and control technology. In…

  12. APPLICATION ANALYSIS REPORT: RETECH PLASMA CENTRIFUGAL FURNACE

    EPA Science Inventory

    This document is an evaluation of the performance of the Retech, Inc. Plasma Centrifugal Furnace (PCF) and its applicability as a treatment for soils contaminated with organic and/or inorganic compounds. Both the technical and economic aspectsof the technology were examined. A...

  13. Predicting Droplet Formation on Centrifugal Microfluidic Platforms

    NASA Astrophysics Data System (ADS)

    Moebius, Jacob Alfred

    Centrifugal microfluidics is a widely known research tool for biological sample and water quality analysis. Currently, the standard equipment used for such diagnostic applications include slow, bulky machines controlled by multiple operators. These machines can be condensed into a smaller, faster benchtop sample-to-answer system. Sample processing is an important step taken to extract, isolate, and convert biological factors, such as nucleic acids or proteins, from a raw sample to an analyzable solution. Volume definition is one such step. The focus of this thesis is the development of a model predicting monodispersed droplet formation and the application of droplets as a technique for volume definition. First, a background of droplet microfluidic platforms is presented, along with current biological analysis technologies and the advantages of integrating such technologies onto microfluidic platforms. Second, background and theories of centrifugal microfluidics is given, followed by theories relevant to droplet emulsions. Third, fabrication techniques for centrifugal microfluidic designs are discussed. Finally, the development of a model for predicting droplet formation on the centrifugal microfluidic platform are presented for the rest of the thesis. Predicting droplet formation analytically based on the volumetric flow rates of the continuous and dispersed phases, the ratios of these two flow rates, and the interfacial tension between the continuous and dispersed phases presented many challenges, which will be discussed in this work. Experimental validation was completed using continuous phase solutions of different interfacial tensions. To conclude, prospective applications are discussed with expected challenges.

  14. Differential white cell count by centrifugal microfluidics.

    SciTech Connect

    Sommer, Gregory Jon; Tentori, Augusto M.; Schaff, Ulrich Y.

    2010-07-01

    We present a method for counting white blood cells that is uniquely compatible with centrifugation based microfluidics. Blood is deposited on top of one or more layers of density media within a microfluidic disk. Spinning the disk causes the cell populations within whole blood to settle through the media, reaching an equilibrium based on the density of each cell type. Separation and fluorescence measurement of cell types stained with a DNA dye is demonstrated using this technique. The integrated signal from bands of fluorescent microspheres is shown to be proportional to their initial concentration in suspension. Among the current generation of medical diagnostics are devices based on the principle of centrifuging a CD sized disk functionalized with microfluidics. These portable 'lab on a disk' devices are capable of conducting multiple assays directly from a blood sample, embodied by platforms developed by Gyros, Samsung, and Abaxis. [1,2] However, no centrifugal platform to date includes a differential white blood cell count, which is an important metric complimentary to diagnostic assays. Measuring the differential white blood cell count (the relative fraction of granulocytes, lymphocytes, and monocytes) is a standard medical diagnostic technique useful for identifying sepsis, leukemia, AIDS, radiation exposure, and a host of other conditions that affect the immune system. Several methods exist for measuring the relative white blood cell count including flow cytometry, electrical impedance, and visual identification from a stained drop of blood under a microscope. However, none of these methods is easily incorporated into a centrifugal microfluidic diagnostic platform.

  15. Flow Pattern Characterization for a Centrifugal Impeller

    NASA Astrophysics Data System (ADS)

    Benavides, Efrén M.

    2014-08-01

    This paper proposes a model for characterizing the flow pattern of a centrifugal impeller attending to the severity of the reverse flow. The model assumes 1) a definition of an escaping particle as the one that flows in every operational point from the trailing edge towards the leading edge of the impeller blades, and 2) a characterization of flow where an operational point is said to have a theoretical flow pattern if it is not possible to establish a fully-reversed escaping particle on it. Therefore, the first part of the article is focused on defining an escaping particle for a centrifugal compressor. The model locates over the map of a centrifugal impeller the line that splits the map in two regions: the region on the right hand side, where a theoretical flow pattern can exist, and the region on the left, where a theoretical flow pattern cannot exist. Therefore, the locus of this line marks a frontier where the expected performance of the impeller cannot be sustained as high as expected. The second part of the article uses a high-performance commercial centrifugal impeller wheel for contrasting the model. A qualitative characterization of the surge line, conclusions and discussions are presented.

  16. Centrifugal Pump Experiment for Chemical Engineering Undergraduates

    ERIC Educational Resources Information Center

    Vanderslice, Nicholas; Oberto, Richard; Marrero, Thomas R.

    2012-01-01

    The purpose of this paper is to describe a Centrifugal Pump Experiment that provided an experiential learning experience to chemical engineering undergraduates at the University of Missouri in the spring of 2010 in the Unit Operations Laboratory course. Lab equipment was used by senior students with computer-based data and control technology. In…

  17. Research centrifuge accommodations on Space Station Freedom

    NASA Technical Reports Server (NTRS)

    Arno, Roger D.; Horkachuk, Michael J.

    1990-01-01

    Life sciences research using plants and animals on the Space Station Freedom requires the ability to maintain live subjects in a safe and low stress environment for long durations at microgravity and at one g. The need for a centrifuge to achieve these accelerations is evident. Programmatic, technical, and cost considerations currently favor a 2.5 meter diameter centrifuge located either in the end cone of a Space Station Freedom node or in a separate module. A centrifuge facility could support a mix of rodent, plant, and small primate habitats. An automated cage extractor could be used to remove modular habitats in pairs without stopping the main rotor, minimizing the disruption to experiment protocols. The accommodation of such a centrifuge facility on the Space Station represents a significant demand on the crew time, power, data, volume, and logistics capability. It will contribute to a better understanding of the effects of space flight on humans, an understanding of plant growth in space for the eventual production of food, and an understanding of the role of gravity in biological processes.

  18. SCHIRRA, WALTER, JR., ASTRONAUT - TRAINING - CENTRIFUGE - PA

    NASA Image and Video Library

    1960-11-22

    G60-02461 (1960) --- Astronaut Walter M. Schirra Jr. prepares to enter gondola of centrifuge which is used to test gravitational stress on astronauts training for spaceflight. Schirra became the pilot of the Mercury-Atlas 8 (MA-8) six-orbit space mission. Photo credit: NASA

  19. Crew Training - Apollo 8 (Centrifuge) - MSC

    NASA Image and Video Library

    1968-11-06

    S68-53283 (1 Nov. 1968) --- The Apollo 8 prime crew is seen inside the gondola during centrifuge training in MSC's Flight Acceleration Facility, Building 29. Left to right, are astronauts William A. Anders, lunar module pilot, James A. Lovell Jr., command module pilot; and Frank Borman, commander. Photo credit: NASA

  20. Extracting hydrocarbons from water using a centrifuge

    NASA Astrophysics Data System (ADS)

    Ryabov, A. Yu.; Ilyina, A. A.; Chuikin, A. V.; Velikov, A. A.

    2014-09-01

    An original method for the solid-phase microextraction of hydrocarbons from water using a centrifuge is proposed. Comparative results from the chromatographic elution of substances after liquid-phase and solid-phase microextraction are presented. The percentage of the extraction of substances from aqueous solutions and the minimum detection limit for aromatic and aliphatic compounds are calculated.

  1. APPLICATION ANALYSIS REPORT: RETECH PLASMA CENTRIFUGAL FURNACE

    EPA Science Inventory

    This document is an evaluation of the performance of the Retech, Inc. Plasma Centrifugal Furnace (PCF) and its applicability as a treatment for soils contaminated with organic and/or inorganic compounds. Both the technical and economic aspectsof the technology were examined. A...

  2. Centrifugal blood pumps for various clinical needs.

    PubMed

    Ichikawa, Seiji; Nosé, Yukihiko

    2002-11-01

    During the past 10 years, different types of blood pumps were developed to address various clinical needs. The Nikkiso centrifugal blood pump was developed for cardiopulmonary bypass application. This blood pump has been widely used in Japan in more than 20% of the cardiopulmonary bypass procedures. The Kyocera C1E3 Gryo pump was developed for short-term circulatory assistance and extracorporeal membrane oxygenation application for up to 2 weeks. This blood pump has been clinically used for up to 28 days without any blood clot formation. Through Phase I of the Japanese government New Energy and Industrial Technology Development Organization (NEDO) program, a chronically implanted centrifugal pump for left ventricular assistance was developed. This pump has already demonstrated its effectiveness, safety, and durability as a 2 year blood pump through in vitro and in vivo experiments. Currently, it is in the process of being converted from an experimental to a clinical device. Through Phase II of the NEDO program, a permanently implantable biventricular assist centrifugal blood pump system is under development. It has demonstrated that the previously mentioned left ventricular assist device blood pump is easily converted into a right ventricular assist pump by simply adding a spacer between the pump and the actuator. This communication discusses the historical development strategies for centrifugal blood pumps and their current status for different clinical needs.

  3. 76 FR 9613 - USEC Inc. (American Centrifuge Lead Cascade Facility and American Centrifuge Plant); Order...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-18

    ... use source and special nuclear material at the Lead Cascade at the Portsmouth Gaseous Diffusion Plant... operate a gas centrifuge uranium enrichment facility (the ACP) at the Portsmouth Gaseous Diffusion...

  4. Mechanisms of Sensorimotor Adaptation to Centrifugation

    NASA Technical Reports Server (NTRS)

    Paloski, W. H.; Wood, S. J.; Kaufman, G. D.

    1999-01-01

    We postulate that centripetal acceleration induced by centrifugation can be used as an inflight sensorimotor countermeasure to retain and/or promote appropriate crewmember responses to sustained changes in gravito-inertial force conditions. Active voluntary motion is required to promote vestibular system conditioning, and both visual and graviceptor sensory feedback are critical for evaluating internal representations of spatial orientation. The goal of our investigation is to use centrifugation to develop an analog to the conflicting visual/gravito-inertial force environment experienced during space flight, and to use voluntary head movements during centrifugation to study mechanisms of adaptation to altered gravity environments. We address the following two hypotheses: (1) Discordant canal-otolith feedback during head movements in a hypergravity tilted environment will cause a reorganization of the spatial processing required for multisensory integration and motor control, resulting in decreased postural stability upon return to normal gravity environment. (2) Adaptation to this "gravito-inertial tilt distortion" will result in a negative after-effect, and readaptation will be expressed by return of postural stability to baseline conditions. During the third year of our grant we concentrated on examining changes in balance control following 90-180 min of centrifugation at 1.4 9. We also began a control study in which we exposed subjects to 90 min of sustained roll tilt in a static (non-rotating) chair. This allowed us to examine adaptation to roll tilt without the hypergravity induced by centrifugation. To these ends, we addressed the question: Is gravity an internal calibration reference for postural control? The remainder of this report is limited to presenting preliminary findings from this study.

  5. A centrifugal pump driven tidal flow extracorporeal membrane oxygenation system tested with neonatal mock circulation.

    PubMed

    Trittenwein, G; Kölbl, R; Trittenwein, H; Golej, J; Burda, G; Hermon, M; Pollak, A

    1999-06-01

    In 1993, Chevalier published his experiences with tidal flow venovenous extracorporeal membrane oxygenation (ECMO) featuring a single lumen cannula, non-occlusive roller pump, and alternating clamps. Using a neonatal mock circulation (NMC), which enables different hemodynamic states for neonatal ECMO research, the tested hypothesis was that it is possible to create a centrifugal pump driven tidal flow neonatal venovenous ECMO system. Additionally, the resulting hemodynamic effects in a condition of circulatory impairment were investigated. The ECMO circuit tested was assembled using a pediatric centrifugal pump head, a distensible reservoir, and a rotary clamp separating drainage from the injection phase. Using the NMC, end tidal volumes, mock circulation flow, and arterial and venous pressures were measured at different pump speeds after the drainage and injection phases. Effective venovenous ECMO flow (evvEF) was calculated. Mock circulation baseline values (ECMO clamped) were compared to values during tidal flow ECMO. At 3,000 rpm, a centrifugal pump speed of 75 ml/kg/min evvEF was reached, and it increased with higher pump speeds. At this point, the end tidal mock circulation flow (representing cardiac output) after drainage differed significantly from that during the injection phase (p < 0.01) but not from the baseline value. The end tidal arterial and venous pressures after the drainage phase were found to be significantly decreased compared to the baselines (p < 0.01). In conclusion, a centrifugal pump driven tidal flow venovenous ECMO system can be created enabling sufficient tidal volumes. Tested in the described NMC simulating posthypoxic circulatory impairment, significant hemodynamic effects could be demonstrated. Animal experiments for confirmation are necessary.

  6. Centrifugal Modelling of Soil Structures. Part I. Centrifugal Modelling of Slope Failures.

    DTIC Science & Technology

    1979-03-01

    section of the clay itself, which was visible to the camera. This latter set of stripes was applied using a variety of trial materials: kaolin powder...investigated slope instability of open cast sulphur and manganese mine waste embankments in the Ukraine, over six years, using the centrifugal modelling...model MW21, and altering the model soil interface with f the centrifuge strongbox by introducing an underlayer of preconsolidated kaolin in two models

  7. Study on vibration suppression based on particle damping in centrifugal field of gear transmission

    NASA Astrophysics Data System (ADS)

    Xiao, Wangqiang; Li, Jiani; Wang, Sheng; Fang, Xiaomeng

    2016-03-01

    Though particle damping technology has been applied to vibration suppression in steady state, there are few reports about the study of particle dampers in centrifugal fields because of its nonlinear damping performance and complex mechanism. Introducing particle damping technology into gear transmission will effectively reduce the vibration from gear engaging, especially for harsh working conditions, such as high temperature and oil lubrication. In this paper, we have explored the mechanism of gear excitation and determined the relationship between the rotational speed and gear's modal parameters in centrifugal fields. A mechanical model of the particle damper based on the discrete element method (DEM) in centrifugal fields has been established. Furthermore, the DEM model has been verified by comparing simulation data with experimental data. Based on the model, we have discussed the particle damper's energy dissipation mechanism in centrifugal fields, as well as the calculation method of energy dissipation. Moreover, the influence of the particle size on energy dissipation characteristics has been analyzed. The results can provide theoretical guidance for vibration and noise reduction of the gear transmission.

  8. Active unsteady aerodynamic suppression of rotating stall in an incompressible flow centrifugal compressor with vaned diffuser

    NASA Technical Reports Server (NTRS)

    Lawless, Patrick B.; Fleeter, Sanford

    1991-01-01

    A mathematical model is developed to analyze the suppression of rotating stall in an incompressible flow centrifugal compressor with a vaned diffuser, thereby addressing the important need for centrifugal compressor rotating stall and surge control. In this model, the precursor to to instability is a weak rotating potential velocity perturbation in the inlet flow field that eventually develops into a finite disturbance. To suppress the growth of this potential disturbance, a rotating control vortical velocity disturbance is introduced into the impeller inlet flow. The effectiveness of this control is analyzed by matching the perturbation pressure in the compressor inlet and exit flow fields with a model for the unsteady behavior of the compressor. To demonstrate instability control, this model is then used to predict the control effectiveness for centrifugal compressor geometries based on a low speed research centrifugal compressor. These results indicate that reductions of 10 to 15 percent in the mean inlet flow coefficient at instability are possible with control waveforms of half the magnitude of the total disturbance at the inlet.

  9. Dual asymmetric centrifugation (DAC)--a new technique for liposome preparation.

    PubMed

    Massing, Ulrich; Cicko, Sanja; Ziroli, Vittorio

    2008-01-04

    This is the first report on the use of a "dual asymmetric centrifuge (DAC)" for preparing liposomes. DAC differs from conventional centrifugation by an additional rotation of the sample around its own vertical axis: While the conventional centrifugation constantly pushes the sample material outwards, this additional rotation constantly forces the sample material towards the center of the centrifuge. This unique combination of two contra rotating movements results in shear forces and thus, in efficient homogenization. We demonstrated that it is possible to prepare liposomes by DAC, by homogenizing a rather concentrated blend of hydrogenated phosphatidylcholine and cholesterol (55:45 mol%) and 0.9% NaCl-solution, which results in a viscous vesicular phospholipid gel (VPG). The resulting VPG can subsequently be diluted to a conventional liposome dispersion. Since DAC is intended to make sterile preparations of liposomes, or to entrap toxic/radioactive compounds, the process was performed within a sealed vial. It could be shown that the DAC speed, the lipid concentration, the homogenization time and the addition of a mixing aid (glass beads) are all critical for the size of the liposomes. Optimized conditions resulted in liposomes of 60+/-5 nm and a trapping efficacy of 56+/-3.3% for the model compound calcein.

  10. Novel localized heating technique on centrifugal microfluidic disc with wireless temperature monitoring system.

    PubMed

    Joseph, Karunan; Ibrahim, Fatimah; Cho, Jongman

    2015-01-01

    Recent advances in the field of centrifugal microfluidic disc suggest the need for electrical interface in the disc to perform active biomedical assays. In this paper, we have demonstrated an active application powered by the energy harvested from the rotation of the centrifugal microfluidic disc. A novel integration of power harvester disc onto centrifugal microfluidic disc to perform localized heating technique is the main idea of our paper. The power harvester disc utilizing electromagnetic induction mechanism generates electrical energy from the rotation of the disc. This contributes to the heat generation by the embedded heater on the localized heating disc. The main characteristic observed in our experiment is the heating pattern in relative to the rotation of the disc. The heating pattern is monitored wirelessly with a digital temperature sensing system also embedded on the disc. Maximum temperature achieved is 82 °C at rotational speed of 2000 RPM. The technique proves to be effective for continuous heating without the need to stop the centrifugal motion of the disc.

  11. Continuous back extraction operation by a single liquid-liquid centrifugal extractor

    SciTech Connect

    Nakase, M.; Takeshita, K.

    2013-07-01

    We have developed a small, high-performance liquid-liquid countercurrent centrifugal extractor for the nuclear fuel cycle. The single extractor allows extraction with many multiple theoretical stages due to the formation of Taylor vortices. We have previously demonstrated multistage extraction for a forward extraction system. In this study, we have applied the centrifugal extractor to a continuous back extraction system with di(2-ethylhexyl)phosphoric acid. We examined the performance of our concept of the centrifugal extractor by varying the rotational speeds of the inner rotor and the nitric acid concentration in the stripping solution. The dispersion behavior, flow characteristics were determined and the back extraction performance was examined for a single chemical species and for multiple species. Complete back extraction by continuous process was achieved and it showed the possibility to minimize the volume and nitric acid concentration of the stripping solution. Our centrifugal extractors may provide a more effective separation system than the conventional separation process that uses many continuously connected extractors. (authors)

  12. An Experimental Study of Cavitation Detection in a Centrifugal Pump Using Envelope Analysis

    NASA Astrophysics Data System (ADS)

    Tan, Chek Zin; Leong, M. Salman

    Cavitation represents one of the most common faults in pumps and could potentially lead to a series of failure in mechanical seal, impeller, bearing, shaft, motor, etc. In this work, an experimental rig was setup to investigate cavitation detection using vibration envelope analysis method, and measured parameters included sound, pressure and flow rate for feasibility of cavitation detection. The experiment testing included 3 operating points of the centrifugal pump (B.E.P, 90% of B.E.P and 80% of B.E.P). Suction pressure of the centrifugal pump was decreased gradually until the inception point of cavitation. Vibration measurements were undertaken at various locations including casing, bearing, suction and discharge flange of the centrifugal pump. Comparisons of envelope spectrums under cavitating and non-cavitating conditions were presented. Envelope analysis was proven useful in detecting cavitation over the 3 testing conditions. During the normal operating condition, vibration peak synchronous to rotational speed was more pronounced. It was however during cavitation condition, the half order sub-harmonic vibration component was clearly evident in the envelope spectrums undertaken at all measurement locations except at the pump bearing. The possible explanation of the strong sub-harmonic (½ of BPF) during cavitation existence in the centrifugal pump was due to insufficient time for the bubbles to collapse completely before the end of the single cycle.

  13. Experimental validation of single pass ion cyclotron resonance absorption in a high speed flowing plasma applied to the variable specific impulse magnetoplasma rocket (VASIMR)

    NASA Astrophysics Data System (ADS)

    Davis, Christopher Nelson

    The topic of this thesis is the experimental characterization and analysis of single pass ion cyclotron resonance heating as applied to acceleration of ions for electric propulsion. The experimental work was done on the VX-10 experiment of the VASIMR (Variable Specific Impulse Magnetoplasma Rocket) concept. In ion cyclotron resonance heating (ICRH) a RF wave is launched into a magnetized plasma where it then accelerates the ions by increasing their rotational speed around the magnetic field lines. The electric field vector of the right hand component of the wave will rotate around the field lines with a frequency oRF in the same direction as the ion's cyclotron motion about the field lines. Consequently, when oRF ≈ oci (where oci is the ion's cyclotron frequency) the force from the electric field of the wave on the ions will result in a continuous rotational energy gain. The perpendicular velocity of the ions generated by ICRH is then converted into axial velocity by the decreasing gradient of the axial magnetic field at the exhaust of the propulsion system from conservation of the magnet moment. This increase in axial velocity is predicted to cause a decrease in density due to conservation of current in the plasma. In order to characterize this density drop during ion cyclotron heating, a single channel interferometer system was developed and implemented on the VX-10. Interferometer density measurements were taken at three different locations on the VX-10 experiment upstream and downstream of the ion acceleration zone. Measurements were made of the density drop in both Helium and Deuterium plasma discharges during ICRH under a variety of operating conditions including magnetic field profile, gas flow rate and ICRH power pulse timing, and ICRH power. A clear measurement of a density drop was observed downstream of the ion resonance zone characteristic of ion acceleration and measurement of little change in density upstream of the resonance zone where no

  14. Design and prototyping of micro centrifugal compressor for ultra micro gas turbine

    NASA Astrophysics Data System (ADS)

    Mizuki, Shimpei; Hirano, Toshiyuki; Koizumi, Yoshiyuki; Minorikawa, Gaku; Tsujita, Hoshio; Iwahara, Mitsuo; Gu, Ronglei; Ohta, Yutaka; Outa, Eisuke

    2005-12-01

    In order to establish the design methodology of an ultra micro centrifugal compressor, which is the most important component of an ultra micro gas turbine unit, a 10 times size of the final target compressor (impeller outer diameter 40 mm, corrected rotational speed 220,000 r/min) was designed. The problems to be solved for downsizing were examined and a 2-dimensional impeller was chosen as the first model due to its productivity. The conventional 1D prediction method and CFD were used. The prototyped compressor was tested by using cold air at the reduced speed of 110,000 r/min. Following to the 10 times model, a 5 times size of the final target model having fully 3-dimensional shape (impeller outer diameter 20mm, corrected rotational speed 500,000 r/min) was designed and tested by using hot gas at the reduced speed of 250,000 r/min.

  15. Dependence of optimal separative power of the “high-speed” Iguasu centrifuge on pressure of working gas

    NASA Astrophysics Data System (ADS)

    Bogovalov, S. V.; Borman, V. D.; Borisevich, V. D.; Davidenko, O. V.; Tronin, I. V.; Tronin, V. N.

    2016-09-01

    The results of optimization calculations of the separative power of the ’’high-speed” Iguasu gas centrifuge are presented. Iguasu gas centrifuge has the rotational speed of 1000 m/s, the rotor length of 1 m. The dependence of the optimal separative power on the pressure of the working gas on the rotor wall was obtained using the numerical simulations. It is shown, that maximum of the optimal separative power corresponds to the pressure of 1100 mmHg. Maximum value of separative power is 31.9 SWU.

  16. Centrifugal instability of semidilute non-Brownian fiber suspensions

    NASA Astrophysics Data System (ADS)

    Gupta, V. K.; Sureshkumar, R.; Khomami, B.; Azaiez, J.

    2002-06-01

    Linear stability of the Taylor-Couette (TC) flow of semidilute non-Brownian suspension is investigated by utilizing the fiber orientation model developed by Hinch and Leal [J. Fluid Mech. 76, 187 (1976)] in conjunction with a quadratic and hybrid closure proposed by Advani and Tucker [J. Rheol. 34, 367 (1990)]. It is found that irrespective of the closure approximation used the fiber additives suppress the centrifugal TC instability, i.e., the critical Reynolds number (Re) increases with the fiber volume fraction and aspect ratio as well as the interfiber interaction coefficient. This increase in the critical Re is significantly larger than that in the total viscosity, except for very small values of the volume fraction and the interaction coefficient. The enhanced stabilization can be attributed to the fact that the suspension develops negative first and second normal stresses in the TC flow when the inner cylinder rotates and the outer one is stationary, i.e., the fluid is in a state of compression. Moreover, the interfiber interactions result in alignment of the fiber orientation tensor with respect to the rate of deformation tensor. This coupling enhances the ability of the fluid elements to resist the amplification of radial velocity disturbances that give rise to the centrifugal instability. This mechanism is substantiated based on a rigorous energy analysis, demonstrating that the coupling between the fiber orientation and perturbation radial velocities gives rise to fiber-induced perturbation shear stresses that are dissipative. Specifically, the coupling of fiber-induced perturbation shear stresses with the base flow velocity leads to a compressive force that dissipates energy leading to the suppression of the centrifugal instability.

  17. Axial and Centrifugal Compressor Mean Line Flow Analysis Method

    NASA Technical Reports Server (NTRS)

    Veres, Joseph P.

    2009-01-01

    This paper describes a method to estimate key aerodynamic parameters of single and multistage axial and centrifugal compressors. This mean-line compressor code COMDES provides the capability of sizing single and multistage compressors quickly during the conceptual design process. Based on the compressible fluid flow equations and the Euler equation, the code can estimate rotor inlet and exit blade angles when run in the design mode. The design point rotor efficiency and stator losses are inputs to the code, and are modeled at off design. When run in the off-design analysis mode, it can be used to generate performance maps based on simple models for losses due to rotor incidence and inlet guide vane reset angle. The code can provide an improved understanding of basic aerodynamic parameters such as diffusion factor, loading levels and incidence, when matching multistage compressor blade rows at design and at part-speed operation. Rotor loading levels and relative velocity ratio are correlated to the onset of compressor surge. NASA Stage 37 and the three-stage NASA 74-A axial compressors were analyzed and the results compared to test data. The code has been used to generate the performance map for the NASA 76-B three-stage axial compressor featuring variable geometry. The compressor stages were aerodynamically matched at off-design speeds by adjusting the variable inlet guide vane and variable stator geometry angles to control the rotor diffusion factor and incidence angles.

  18. Centrifugal governor for injection type internal combustion engine

    SciTech Connect

    Takahashi, M

    1989-05-23

    A centrifugal governor for an injection type internal combustion engine, comprising: a housing in which a cam shaft is rotatably supported at its lower section and a fuel injection pump is disposed above the cam shaft; a flyweight disposed at an end of the cam shaft so as to be displaced in accordance with a rotational speed of the engine; a tension lever rotatable upon a driving force of the flyweight with an intermediate fixed shaft as a pivot; a governor spring assembly supported so as not to exert any supporting load between a housing side spring seat and another spring seat provided to the tension lever, and so as to be compressed upon rotation of the tension lever; a guide lever and a floating lever, both rotatable with a pin provided at a lower end of the tension lever as a pivot, and normally connected to each other as an integrated element by a cancellation spring surrounding the pin; the speed lever have a shaped like bell crank, rotatably supported at one end with a shaft connecting the control lever as a pivot, and engaged with an intermediated guide of the guide lever at the other end.

  19. [Concordance between the zinc sulphate flotation and centrifugal sedimentation methods for the diagnosis of intestinal parasites].

    PubMed

    Inês, Elizabete De Jesus; Pacheco, Flavia Thamiris Figueiredo; Pinto, Milena Carneiro; Mendes, Patrícia Silva de Almeida; Da Costa-Ribeiro, Hugo; Soares, Neci Matos; Teixeira, Márcia Cristina Aquino

    2016-12-01

    The diagnosis of intestinal parasitic infections depends on the parasite load, the specific gravity density of the parasite eggs, oocysts or cysts, and the density and viscosity of flotation or sedimentation medium where faeces are processed. To evaluate the concordance between zinc sulphate flotation and centrifugal sedimentation in the recovery of parasites in faecal samples of children. Faecal samples of 330 children from day care centers were evaluated by zinc sulphate flotation and centrifugal sedimentation techniques. The frequencies of detection of parasites by each method were determined and the agreement between the diagnostic techniques was evaluated using the kappa index, with 95% confidence intervals. The faecal flotation in zinc sulphate diagnosed significantly more cases of Trichuris trichiura infection when compared to centrifugal sedimentation (39/330; 11.8% vs. 13/330; 3.9%, p<0.001), with low diagnostic concordance between methods (kappa=0.264; 95% CI: 0.102-0.427). Moreover, all positive samples for Enterobius vermicularis eggs (n=5) and Strongyloides stercoralis larvae (n=3) were diagnosed only by zinc sulphate. No statistical differences were observed between methods for protozoa identification. The results showed that centrifugal flotation in zinc sulphate solution was significantly more likely to detect light helminths eggs such as those of T. trichiura and E. vermicularis in faeces than the centrifugal sedimentation process.

  20. Linear and Logarithmic Speed-Accuracy Trade-Offs in Reciprocal Aiming Result from Task-Specific Parameterization of an Invariant Underlying Dynamics

    ERIC Educational Resources Information Center

    Bongers, Raoul M.; Fernandez, Laure; Bootsma, Reinoud J.

    2009-01-01

    The authors examined the origins of linear and logarithmic speed-accuracy trade-offs from a dynamic systems perspective on motor control. In each experiment, participants performed 2 reciprocal aiming tasks: (a) a velocity-constrained task in which movement time was imposed and accuracy had to be maximized, and (b) a distance-constrained task in…

  1. Linear and Logarithmic Speed-Accuracy Trade-Offs in Reciprocal Aiming Result from Task-Specific Parameterization of an Invariant Underlying Dynamics

    ERIC Educational Resources Information Center

    Bongers, Raoul M.; Fernandez, Laure; Bootsma, Reinoud J.

    2009-01-01

    The authors examined the origins of linear and logarithmic speed-accuracy trade-offs from a dynamic systems perspective on motor control. In each experiment, participants performed 2 reciprocal aiming tasks: (a) a velocity-constrained task in which movement time was imposed and accuracy had to be maximized, and (b) a distance-constrained task in…

  2. Supersonic COIL driven by centrifugal bubbling SOG with efficient depletion of chemicals in single pass

    NASA Astrophysics Data System (ADS)

    Zagidullin, Marsel V.; Nikolaev, Valery D.; Khvatov, Nikolay A.; Svistun, Michael I.

    2008-10-01

    An efficient and compact centrifugal bubbling SOG was employed as energy source in supersonic COIL. A centrifugal bubbling SOG generated gas at 100 torr of total pressure providing 90% of chlorine utilization and 60% of O2(1Δ) yield with efficient depletion of BHP chemicals in single pass through SOG. A 1 kW class ejector COIL powered by this SOG demonstrated a specific power of 12.5 W per 1cm3/s of BHP volumetric rate at chemical efficiency 22.7%.

  3. Mechanisms of flow through compressible porous beds in sedimentation, centrifugation, deliquoring, and ceramic processing

    SciTech Connect

    1996-01-25

    The major topics covered in the investigation include: centrifugation; cake filtration; sedimentation and thickening; capillary suction operations; ceramics, slip casting; optimization studies; and wastewater. The research program was aimed at the specific areas of solid/liquid separation including sedimentation, thickening, cake filtration, centrifugation, expression, washing, deep-bed filtration, screening, and membrane separation. Unification of the theoretical approaches to the various solid/liquid separation operations was the principle objective of the research. Exploring new aspects of basic separation mechanisms, verification of theory with experiment, development of laboratory procedures for obtaining data for design, optimizing operational methods, and transferring the results to industry were part of the program.

  4. A centrifugal direct recombinase polymerase amplification (direct-RPA) microdevice for multiplex and real-time identification of food poisoning bacteria.

    PubMed

    Choi, Goro; Jung, Jae Hwan; Park, Byung Hyun; Oh, Seung Jun; Seo, Ji Hyun; Choi, Jong Seob; Kim, Do Hyun; Seo, Tae Seok

    2016-06-21

    In this study, we developed a centrifugal direct recombinase polymerase amplification (direct-RPA) microdevice for multiplex and real-time identification of food poisoning bacteria contaminated milk samples. The microdevice was designed to contain identical triplicate functional units and each unit has four reaction chambers, thereby making it possible to perform twelve direct-RPA reactions simultaneously. The integrated microdevice consisted of two layers: RPA reagents were injected in the top layer, while spiked milk samples with food poisoning bacteria were loaded into sample reservoirs in the bottom layer. For multiplex bacterial detection, the target gene-specific primers and probes were dried in each reaction chamber. The introduced samples and reagents could be equally aliquoted and dispensed into each reaction chamber by centrifugal force, and then the multiplex direct-RPA reaction was executed. The target genes of bacteria spiked in milk could be amplified at 39 °C without a DNA extraction step by using the direct-RPA cocktails, which were a combination of a direct PCR buffer and RPA enzymes. As the target gene amplification proceeded, the increased fluorescence signals coming from the reaction chambers were recorded in real-time at an interval of 2 min. The entire process, including the sample distribution, the direct-RPA reaction, and the real-time analysis, was accomplished with a custom-made portable genetic analyzer and a miniaturized optical detector. Monoplex, duplex, and triplex food poisoning bacteria (Salmonella enterica, Escherichia coli O157:H7, and Vibrio parahaemolyticus) detection was successfully performed with a detection sensitivity of 4 cells per 3.2 μL of milk samples within 30 min. By implementing the direct-PRA on the miniaturized centrifugal microsystem, the on-site food poisoning bacteria analysis would be feasible with high speed, sensitivity, and multiplicity.

  5. Distribution of fluids in the body of the centrifuged rat

    NASA Technical Reports Server (NTRS)

    Pitts, G. C.

    1983-01-01

    The effects of exposure to an elevated g-level throughout the period of rapid growth is investigated in a comparison of a group of female Sprague-Dawley rats centrifuged as adults with other groups centrifuged for prolonged intervals starting shortly after weaning. The fluid-solid composition of total body, heart, liver, gut, skin, and muscle for both study groups is compared with that of a control group. None of the changes as a result of centrifugation were truly persistent. The only increases in mass associated with centrifugation and the only responses to centrifugation per se were observed in the skin values.

  6. Effects of bedrest and centrifugation of humans on serum thyroid function tests.

    NASA Technical Reports Server (NTRS)

    Leach, C. S.; Johnson, P. C.; Driscoll, T. B.

    1972-01-01

    Changes in plasma volume and protein concentration have been reported when normal subjects are bedrested or centrifuged. Since thyroid hormones are transported by specific plasma proteins, each of these procedures could be expected to change plasma levels of these hormones. In this study centrifugation of normal healthy human subjects produced an increased concentration of total protein and albumin. When these same subjects were bedrested for six days, no change in total protein, albumin or thyroxine binding globulin were found although there was an eight per cent decrease in plasma volume. Centrifugation and, to a lesser extent, bedrest produced changes in serum T-4 levels and the T-3 test results. The direction of these changes (decreased % T-3 values and increased T-4 levels) indicate that these two situations produce an increased plasma concentration of thyroxine binding sites.

  7. Effects of bedrest and centrifugation of humans on serum thyroid function tests.

    NASA Technical Reports Server (NTRS)

    Leach, C. S.; Johnson, P. C.; Driscoll, T. B.

    1972-01-01

    Changes in plasma volume and protein concentration have been reported when normal subjects are bedrested or centrifuged. Since thyroid hormones are transported by specific plasma proteins, each of these procedures could be expected to change plasma levels of these hormones. In this study centrifugation of normal healthy human subjects produced an increased concentration of total protein and albumin. When these same subjects were bedrested for six days, no change in total protein, albumin or thyroxine binding globulin were found although there was an eight per cent decrease in plasma volume. Centrifugation and, to a lesser extent, bedrest produced changes in serum T-4 levels and the T-3 test results. The direction of these changes (decreased % T-3 values and increased T-4 levels) indicate that these two situations produce an increased plasma concentration of thyroxine binding sites.

  8. Numerical analysis of flow in ultra micro centrifugal compressor -influence of meridional configuration

    NASA Astrophysics Data System (ADS)

    Kaneko, Masanao; Tsujita, Hoshio; Hirano, Toshiyuki

    2013-04-01

    A single stage ultra micro centrifugal compressor constituting ultra micro gas turbine is required to operate at high rotational speed in order to achieve the pressure ratio which establishes the gas turbine cycle. As a consequence, the aerodynamic losses can be increased by the interaction of a shock wave with the boundary layer on the blade surface. Moreover, the centrifugal force which exceeds the allowable stress of the impeller material can act on the root of blades. On the other hand, the restrictions of processing technology for the downsizing of impeller not only relatively enlarge the size of tip clearance but also make it difficult to shape the impeller with the three-dimensional blade. Therefore, it is important to establish the design technology for the impeller with the two-dimensional blade which possesses the sufficient aerodynamic performance and enough strength to bear the centrifugal force caused by the high rotational speed. In this study, the flow in two types of impeller with the two-dimensional blade which have different meridional configuration was analyzed numerically. The computed results clarified the influence of the meridional configuration on the loss generations in the impeller passage.

  9. Centrifugation-Free Magnetic Isolation of Functional Mitochondria Using Paramagnetic Iron Oxide Nanoparticles.

    PubMed

    Banik, Bhabatosh; Dhar, Shanta

    2017-09-01

    Subcellular fractionation techniques are essential for cell biology and drug development studies. The emergence of organelle-targeted nanoparticle (NP) platforms necessitates the isolation of target organelles to study drug delivery and activity. Mitochondria-targeted NPs have attracted the attention of researchers around the globe, since mitochondrial dysfunctions can cause a wide range of diseases. Conventional mitochondria isolation methods involve high-speed centrifugation. The problem with high-speed centrifugation-based isolation of NP-loaded mitochondria is that NPs can pellet even if they are not bound to mitochondria. We report development of a mitochondria-targeted paramagnetic iron oxide nanoparticle, Mito-magneto, that enables isolation of mitochondria under the influence of a magnetic field. Isolation of mitochondria using Mito-magneto eliminates artifacts typically associated with centrifugation-based isolation of NP-loaded mitochondria, thus producing intact, pure, and respiration-active mitochondria. © 2017 by John Wiley & Sons, Inc. Copyright © 2017 John Wiley & Sons, Inc.

  10. The Effect of Geometry on the Efficiency and Hemolysis of Centrifugal Implantable Blood Pumps.

    PubMed

    Mozafari, Sahand; Rezaienia, Mohammad A; Paul, Gordon M; Rothman, Martin T; Wen, Pihua; Korakianitis, Theodosios

    The application of centrifugal pumps as heart assist devices imposes design limitations on the impeller geometry. Geometry and operating parameters will affect the performance and the hemocompatibility of the device. Among all the parameters affecting the hemocompatibility, pressure, rotational speed, blade numbers, angle, and width have significant impact on the blood trauma. These parameters directly (pressure, speed) and indirectly (geometry) affect the efficiency of the pump as well. This study describes the experimental investigation on geometric parameters and their effect on the performance of small centrifugal pumps suitable for Mechanical Circulatory Support (MCS) devices. Experimental and numerical techniques were implemented to analyze the performance of 15 centrifugal impellers with different characteristics. The effect of each parameter on the pump performance and hemolysis was studied by calculating the normalized index of hemolysis (NIH) and the shear stress induced in each pump. The results show five and six blades, 15-35° outlet angle, and the lowest outlet width that meets the required pressure rise are optimum values for an efficient hemocompatible pump.

  11. Self-Assembly of Ag Nanoparticles Induced by Centrifuging and Broken by Silanization.

    PubMed

    Yang, Ping; Zhang, Yulan

    2015-08-01

    A novel method was developed to assemble Ag nanoparticles (NPs) into chain-like structures. The assembly of the NPs was created by suspending in an ethanol and water solution as well as centrifuging at a high speed (a force of more than 29 Kg for the NPs with an average diameter of 18 nm). The composition of solvents and centrifuged speeds of samples play important roles for the formation of regular assemblies. The number of Ag NPs in the chain-like assemblies was adjusted by changing centrifuging forces. The assemblies of the NPs were fixed by a SiO2 coating through a St6ber synthesis. In addition, the assemblies were broken through a silanization process because of partially hydrolyzed tetraethyl-orthosilicate molecules adsorbed on the surface of Ag NPs to form a SiO2 layer opposite aggregation. A slow silanization process made Ag NPs monodispersed in solutions, in which Ag/SiO2 core/shell NPs were created.

  12. Numerical analysis of the internal flow field in screw centrifugal blood pump based on CFD

    NASA Astrophysics Data System (ADS)

    Han, W.; Han, B. X.; Y Wang, H.; Shen, Z. J.

    2013-12-01

    As to the impeller blood pump, the high speed of the impeller, the local high shear force of the flow field and the flow dead region are the main reasons for blood damage. The screw centrifugal pump can effectively alleviate the problems of the high speed and the high shear stress for the impeller. The softness and non-destructiveness during the transfer process can effectively reduce the extent of the damage. By using CFD software, the characteristics of internal flow are analyzed in the screw centrifugal pump by exploring the distribution rules of the velocity, pressure and shear deformation rate of the blood when it flows through the impeller and the destructive effects of spiral blades on blood. The results show that: the design of magnetic levitation solves the sealing problems; the design of regurgitation holes solves the problem of the flow dead zone; the magnetic levitated microcirculation screw centrifugal pump can effectively avoid the vortex, turbulence and high shear forces generated while the blood is flowing through the pump. Since the distribution rules in the velocity field, pressure field and shear deformation rate of the blood in the blood pump are comparatively uniform and the gradient change is comparatively small, the blood damage is effectively reduced.

  13. Effects of Impeller-Diffuser Interaction on Centrifugal Compressor Performance

    NASA Technical Reports Server (NTRS)

    Tan, Choon S.

    2003-01-01

    This research program focuses on characterizing the effect of impeller-diffuser interactions in a centrifugal compressor stage on its performance using unsteady threedimensional Reynolds-averaged Navier-Stokes simulations. The computed results show that the interaction between the downstream diffuser pressure field and the impeller tip clearance flow can account for performance changes in the impeller. The magnitude of performance change due to this interaction was examined for an impeller with varying tip clearance followed by a vaned or vaneless diffuser. The impact of unsteady impeller-diffuser interaction, primarily through the impeller tip clearance flow, is reflected through a time-averaged change in impeller loss, blockage and slip. The results show that there exists a tip clearance where the beneficial effect of the impeller-diffuser interaction on the impeller performance is at a maximum. A flow feature that consists of tip flow back leakage was shown to occur at design speed for the centrifugal compressor stage. This flow phenomenon is described as tip flow that originates in one passage, flows downstream of the impeller trailing edge and then returns to upstream of the impeller trailing edge of a neighboring passage. Such a flow feature is a source of loss in the impeller. A hypothesis is put forth to show that changing the diffuser vane count and changing impeller-diffuser gap has an analogous effect on the impeller performance. The centrifugal compressor stage was analyzed using diffusers of different vane counts, producing an impeller performance trend similar to that when the impeller-diffuser gap was varied, thus supporting the hypothesis made. This has the implication that the effect impeller performance associated with changing the impeller-diffuser gap and changing diffuser vane count can be described by the non-dimensional ratio of impeller-diffuser gap to diffuser vane pitch. A procedure is proposed and developed for isolating impeller passage

  14. A study of energy dissipation and critical speed of granular flow in a rotating cylinder

    NASA Astrophysics Data System (ADS)

    Dragomir, Sergiu C.; Sinnott, Mathew D.; Semercigil, S. Eren; Turan, Özden F.

    2014-12-01

    Tuned vibration absorbers may improve the safety of flexible structures which are prone to excessive oscillation magnitudes under dynamic loads. A novel absorber design proposes sloshing of granular material in a rotating cylinder where the granular material is the energy dissipating agent. As the conventional dissipative elements require maintenance due to the nature of their function, the new design may represent a virtually maintenance free alternative. The angular speed of the cylinder containing particles has a critical centrifuging speed, after which particles remain permanently in contact with the walls and there can be no further dissipation. Until the critical speed, however, dissipation increases proportionally with the angular speed. It is then vital to know the value of the critical speed as the limit of dissipation. The focus of the present study is on determination of the critical centrifuge speed. This critical speed is also of practical importance in bulk-material handling rotary mills, such as dryers and crushers. Experiments and numerical simulations, using Discrete Element Method, are used to determine the critical centrifuging speed. In addition, predictions are given and guidelines are offered for the choice of material properties to maximize the energy dissipation. As a result of a parametric study, the coefficient of friction is found to have the greatest significance on the centrifuging speed.

  15. Axial and centrifugal pump meanline performance analysis

    NASA Technical Reports Server (NTRS)

    Veres, Joseph P.

    1994-01-01

    A meanline pump flow modeling method has been developed to provide a fast capability for modeling pumps of cryogenic rocket engines. Based on this method, a meanline pump flow code (PUMPA) has been written that can predict the performance of pumps at off-design operating conditions, given the loss of the diffusion system at the design point. The design point rotor efficiency is obtained from empirically derived correlations of loss to rotor specific speed. The rapid input setup and computer run time for the meanline pump flow code makes it an effective analysis and conceptual design tool. The map generation capabilities of the PUMPA code provide the information needed for interfacing with a rocket engine system modeling code.

  16. Small centrifugal pumps for low thrust rockets

    NASA Technical Reports Server (NTRS)

    Gulbrandsen, N. C.; Furst, R. B.; Burgess, R. M.; Scheer, D. D.

    1985-01-01

    This paper presents the results of a combined analytical and experimental investigation of low specific speed pumps for potential use as components of propellant feed systems for low thrust rocket engines. Shrouded impellers and open face impellers were tested in volute type and vaned diffuser type pumps. Full- and partial-emission diffusers and full- and partial-admission impellers were tested. Axial and radial loads, head and efficiency versus flow, and cavitation tests were conducted. Predicted performance of two pumps are compared when pumping water and liquid hydrogen. Detailed pressure loss and parasitic power values are presented for two pump configurations. Partial-emission diffusers were found to permit use of larger impeller and diffuser passages with a minimal performance penalty. Normal manufacturing tolerances were found to result in substantial power requirement variation with only a small pressure rise change. Impeller wear ring leakage was found to reduce pump pressure rise to an increasing degree as the pump flowrate was decreased.

  17. Small centrifugal pumps for low thrust rockets

    NASA Technical Reports Server (NTRS)

    Gulbrandsen, N. C.; Furst, R. B.; Burgess, R. M.; Scheer, D. D.

    1985-01-01

    This paper presents the results of a combined analytical and experimental investigation of low specific speed pumps for potential use as components of propellant feed systems for low thrust rocket engines. Shrouded impellers and open face impellers were tested in volute type and vaned diffuser type pumps. Full- and partial-emission diffusers and full- and partial-admission impellers were tested. Axial and radial loads, head and efficiency versus flow, and cavitation tests were conducted. Predicted performance of two pumps are compared when pumping water and liquid hydrogen. Detailed pressure loss and parasitic power values are presented for two pump configurations. Partial-emission diffusers were found to permit use of larger impeller and diffuser passages with a minimal performance penalty. Normal manufacturing tolerances were found to result in substantial power requirement variation with only a small pressure rise change. Impeller wear ring leakage was found to reduce pump pressure rise to an increasing degree as the pump flowrate was decreased.

  18. Spaceborne centrifugal relays for spacecraft propulsion

    NASA Technical Reports Server (NTRS)

    Ouzidane, Malika

    1991-01-01

    Acceleration using centrifugal relays is a recently discovered method for the acceleration of spaceborne payloads to high velocity at high thrust. Centrifugal relays are moving rotors which progressively accelerate reaction mass to higher velocities. One important engineering problem consists of accurately tracking the position of the projectiles and rotors and guiding each projectile exactly onto the appropriate guide tracks on each rotor. The topics of this research are the system kinematics and dynamics and the computerized guidance system which will allow the projectile to approach each rotor with exact timing with respect to the rotor rotation period and with very small errors in lateral positions. Kinematics studies include analysis of rotor and projectile positions versus time and projectile/rotor interactions. Guidance studies include a detailed description of the tracking mechanism (interrupt of optical beams) and the aiming mechanism (electromagnetic focusing) including the design of electromagnetic deflection coils and the switching circuitry.

  19. Continuous centrifuge decelerator for polar molecules.

    PubMed

    Chervenkov, S; Wu, X; Bayerl, J; Rohlfes, A; Gantner, T; Zeppenfeld, M; Rempe, G

    2014-01-10

    Producing large samples of slow molecules from thermal-velocity ensembles is a formidable challenge. Here we employ a centrifugal force to produce a continuous molecular beam with a high flux at near-zero velocities. We demonstrate deceleration of three electrically guided molecular species, CH3F, CF3H, and CF3CCH, with input velocities of up to 200  m s(-1) to obtain beams with velocities below 15  m s(-1) and intensities of several 10(9)  mm(-2) s(-1). The centrifuge decelerator is easy to operate and can, in principle, slow down any guidable particle. It has the potential to become a standard technique for continuous deceleration of molecules.

  20. High stability design for new centrifugal compressor

    NASA Technical Reports Server (NTRS)

    Kanki, H.; Katayama, K.; Morii, S.; Mouri, Y.; Umemura, S.; Ozawa, U.; Oda, T.

    1989-01-01

    It is essential that high-performance centrifugal compressors be free of subsynchronous vibrations. A new high-performance centrifugal compressor has been developed by applying the latest rotordynamics knowledge and design techniques: (1) To improve the system damping, a specially designed oil film seal was developed. This seal attained a damping ratio three times that of the conventional design. The oil film seal contains a special damper ring in the seal cartridge. (2) To reduce the destabilizing effect of the labyrinth seal, a special swirl canceler (anti-swirl nozzle) was applied to the balance piston seal. (3) To confirm the system damping margin, the dynamic simulation rotor model test and the full load test applied the vibration exciting test in actual load conditions.