Science.gov

Sample records for spectrometer barrel level-1

  1. The CMS Level-1 Trigger Barrel Track Finder

    NASA Astrophysics Data System (ADS)

    Ero, J.; Evangelou, I.; Flouris, G.; Foudas, C.; Guiducci, L.; Loukas, N.; Manthos, N.; Papadopoulos, I.; Paradas, E.; Sotiropoulos, S.; Sphicas, P.; Triossi, A.; Wulz, C.

    2016-03-01

    The design and performance of the upgraded CMS Level-1 Trigger Barrel Muon Track Finder (BMTF) is presented. Monte Carlo simulation data as well as cosmic ray data from a CMS muon detector slice test have been used to study in detail the performance of the new track finder. The design architecture is based on twelve MP7 cards each of which uses a Xilinx Virtex-7 FPGA and can receive and transmit data at 10 Gbps from 72 input and 72 output fibers. According to the CMS Trigger Upgrade TDR the BMTF receives trigger primitive data which are computed using both RPC and DT data and transmits data from a number of muon candidates to the upgraded Global Muon Trigger. Results from detailed studies of comparisons between the BMTF algorithm results and the results of a C++ emulator are also presented. The new BMTF will be commissioned for data taking in 2016.

  2. Propagation of spectral characterization errors of imaging spectrometers at level-1 and its correction within a level-2 recalibration scheme

    NASA Astrophysics Data System (ADS)

    Vicent, Jorge; Alonso, Luis; Sabater, Neus; Miesch, Christophe; Kraft, Stefan; Moreno, Jose

    2015-09-01

    The uncertainties in the knowledge of the Instrument Spectral Response Function (ISRF), barycenter of the spectral channels and bandwidth / spectral sampling (spectral resolution) are important error sources in the processing of satellite imaging spectrometers within narrow atmospheric absorption bands. The exhaustive laboratory spectral characterization is a costly engineering process that differs from the instrument configuration in-flight given the harsh space environment and harmful launching phase. The retrieval schemes at Level-2 commonly assume a Gaussian ISRF, leading to uncorrected spectral stray-light effects and wrong characterization and correction of the spectral shift and smile. These effects produce inaccurate atmospherically corrected data and are propagated to the final Level-2 mission products. Within ESA's FLEX satellite mission activities, the impact of the ISRF knowledge error and spectral calibration at Level-1 products and its propagation to Level-2 retrieved chlorophyll fluorescence has been analyzed. A spectral recalibration scheme has been implemented at Level-2 reducing the errors in Level-1 products below the 10% error in retrieved fluorescence within the oxygen absorption bands enhancing the quality of the retrieved products. The work presented here shows how the minimization of the spectral calibration errors requires an effort both for the laboratory characterization and for the implementation of specific algorithms at Level-2.

  3. Barrels XXIX: Barrels go Hollywood.

    PubMed

    Evans, Mathew H; Brumberg, Joshua C

    2017-03-01

    Barrels XXIX brought together researchers focusing on the rodent barrel cortex and associated systems. The meeting revolved around three themes: thalamocortical interactions in motor control, touch in rodent, monkey, and humans, and the nature of the multisensory computations the brain makes. Over two days these topics were covered as well as many more presentations that focused on the physiology, behavior, and development of the rodent whisker-to-barrel cortex system.

  4. Computer vision barrel inspection

    NASA Astrophysics Data System (ADS)

    Wolfe, William J.; Gunderson, James; Walworth, Matthew E.

    1994-02-01

    One of the Department of Energy's (DOE) ongoing tasks is the storage and inspection of a large number of waste barrels containing a variety of hazardous substances. Martin Marietta is currently contracted to develop a robotic system -- the Intelligent Mobile Sensor System (IMSS) -- for the automatic monitoring and inspection of these barrels. The IMSS is a mobile robot with multiple sensors: video cameras, illuminators, laser ranging and barcode reader. We assisted Martin Marietta in this task, specifically in the development of image processing algorithms that recognize and classify the barrel labels. Our subsystem uses video images to detect and locate the barcode, so that the barcode reader can be pointed at the barcode.

  5. Barrel Stave Flextensional Projector

    DTIC Science & Technology

    1999-02-23

    end stave flextensional transducer having piezoelectric elements cap, both end caps having a circular shape. A plurality of for producing an acoustic...TITLE AND SUBTITLE 5a. CONTRACT NUMBER Barrel Stave Flextensional Projector 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER...54] BARREL STAVE FLEXTENSIONAL Atomey, Agent, or Firm-Ron Billi PROJECTOR [57] ABSTRACT [75] Inventor: Robert A Dechico, Pennington, N.J. An

  6. CALIFA Barrel prototype detector characterisation

    NASA Astrophysics Data System (ADS)

    Pietras, B.; Gascón, M.; Álvarez-Pol, H.; Bendel, M.; Bloch, T.; Casarejos, E.; Cortina-Gil, D.; Durán, I.; Fiori, E.; Gernhäuser, R.; González, D.; Kröll, T.; Le Bleis, T.; Montes, N.; Nácher, E.; Robles, M.; Perea, A.; Vilán, J. A.; Winkel, M.

    2013-11-01

    Well established in the field of scintillator detection, Caesium Iodide remains at the forefront of scintillators for use in modern calorimeters. Recent developments in photosensor technology have lead to the production of Large Area Avalanche Photo Diodes (LAAPDs), a huge advancement on traditional photosensors in terms of high internal gain, dynamic range, magnetic field insensitivity, high quantum efficiency and fast recovery time. The R3B physics programme has a number of requirements for its calorimeter, one of the most challenging being the dual functionality as both a calorimeter and a spectrometer. This involves the simultaneous detection of ∼300 MeV protons and gamma rays ranging from 0.1 to 20 MeV. This scintillator - photosensor coupling provides an excellent solution in this capacity, in part due to the near perfect match of the LAAPD quantum efficiency peak to the light output wavelength of CsI(Tl). Modern detector development is guided by use of Monte Carlo simulations to predict detector performance, nonetheless it is essential to benchmark these simulations against real data taken with prototype detector arrays. Here follows an account of the performance of two such prototypes representing different polar regions of the Barrel section of the forthcoming CALIFA calorimeter. Measurements were taken for gamma-ray energies up to 15.1 MeV (Maier-Leibnitz Laboratory, Garching, Germany) and for direct irradiation with a 180 MeV proton beam (The Svedberg Laboratoriet, Uppsala, Sweden). Results are discussed in light of complementary GEANT4 simulations.

  7. The PANDA Barrel DIRC

    NASA Astrophysics Data System (ADS)

    Dzhygadlo, R.; Schwarz, C.; Belias, A.; Gerhardt, A.; Götzen, K.; Kalicy, G.; Krebs, M.; Lehmann, D.; Nerling, F.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwiening, J.; Traxler, M.; Zühlsdorf, M.; Britting, A.; Eyrich, W.; Lehmann, A.; Pfaffinger, M.; Uhlig, F.; Düren, M.; Etzelmüller, E.; Föhl, K.; Hayrapetyan, A.; Kröck, B.; Merle, O.; Rieke, J.; Schmidt, M.; Cowie, E.; Keri, T.; Achenbach, P.; Cardinali, M.; Hoek, M.; Lauth, W.; Schlimme, S.; Sfienti, C.; Thiel, M.

    2016-05-01

    The PANDA detector at the international accelerator Facility for Antiproton and Ion Research in Europe (FAIR) addresses fundamental questions of hadron physics. Experiments concerning charmonium spectroscopy, the search for hybrids and glueballs and the interaction of hidden and open charm particles with nucleons and nuclei will be performed with antiproton beams impinging on hydrogen or nuclear targets. Cooled beams allow the precision scan of resonances in formation experiments. The momentum range of the antiproton beam between 1.5 GeV/c and 15 GeV/c tests predictions by perturbation theory and will reveal deviations originating from strong QCD . An excellent hadronic particle identification will be accomplished by DIRC (Detection of Internally Reflected Cherenkov light) counters. The design for the barrel region is based on the successful BaBar DIRC with several key improvements, such as fast photon timing and a compact imaging region. DIRC designs based on different radiator geometries with several focusing options were studied in simulation. The performance of each design was characterized in terms of photon yield and single photon Cherenkov angle resolution. Selected design options were implemented in prototypes and tested with hadronic particle beams at GSI and CERN.

  8. BARREL Team Launching 20 Balloons

    NASA Image and Video Library

    A movie made by the NASA-Funded Balloon Array for Radiation belt Relativistic Electron Losses, or BARREL, team on their work launching 20 balloons in Antarctica during the Dec. 2013/Jan. 2014 campa...

  9. Variant M4 Barrel Characterization

    DTIC Science & Technology

    2009-07-01

    an Instron Wilson-Tukon micro hardness - tester using a Knoop indenter with a 200g load. Knoop hardness values where then converted to 3 Rockwell ...relatively thin and localized to wide cracks and surfaces where the chromium has been completely removed. All fired barrels show extensive copper ...barrels had large deposits of copper at the root of the lands; in addition to collecting copper and firing debris at surface cracks and disparities

  10. TES Level 1B

    Atmospheric Science Data Center

    2014-12-08

    TES Level 1B data files contain radiometric calibrated spectral radiances and their ... and some engineering data are also provided. A Level 1B data file contains data from a single TES orbit for one focal ... as the Aura orbit number at the time of the South Pole apex crossing. version id represents the version identification number, ...

  11. OSIRIS camera barrel optomechanical design

    NASA Astrophysics Data System (ADS)

    Farah, Alejandro; Tejada, Carlos; Gonzalez, Jesus; Cobos, Francisco J.; Sanchez, Beatriz; Fuentes, Javier; Ruiz, Elfego

    2004-09-01

    A Camera Barrel, located in the OSIRIS imager/spectrograph for the Gran Telescopio Canarias (GTC), is described in this article. The barrel design has been developed by the Institute for Astronomy of the University of Mexico (IA-UNAM), in collaboration with the Institute for Astrophysics of Canarias (IAC), Spain. The barrel is being manufactured by the Engineering Center for Industrial Development (CIDESI) at Queretaro, Mexico. The Camera Barrel includes a set of eight lenses (three doublets and two singlets), with their respective supports and cells, as well as two subsystems: the Focusing Unit, which is a mechanism that modifies the first doublet relative position; and the Passive Displacement Unit (PDU), which uses the third doublet as thermal compensator to maintain the camera focal length and image quality when the ambient temperature changes. This article includes a brief description of the scientific instrument; describes the design criteria related with performance justification; and summarizes the specifications related with misalignment errors and generated stresses. The Camera Barrel components are described and analytical calculations, FEA simulations and error budgets are also included.

  12. Erosion in Large Gun Barrels

    DTIC Science & Technology

    1975-01-01

    AD-A017-104 EROSION IN LARGE GUN BARRELS National Materials Advisory Board (NAS-NAE) Washington, D. C. 1975 i OD O i...KCEUMk MO Erosion in Large Quo Barrels « »CIIPOMMIHO 0»C MK»0"T NUMK* • COWtWACT OM GHAnT NUMIEIV.I •UTH. National Materials Advisory...Ad Hoc Committee on Gun Tube Erosion MDA903-74-C-0167 — • PCMFOMMIMG 0*)0AMIIAT|©M H «Ml AMD AOO«eSS National Materials Advisory Board

  13. Superior Barrel & Drum, Elk Township, New Jersey

    EPA Pesticide Factsheets

    The Superior Barrel and Drum Superfund site is a 5.5-acre property located in Elk Township, Gloucester County, New Jersey. Superior Barrel and Drum is listed as a drum reconditioning business. These facilities typically clean and recondition metal

  14. The bar PANDA Barrel-TOF Detector at FAIR

    NASA Astrophysics Data System (ADS)

    Zimmermann, S.; Suzuki, K.; Steinschaden, D.; Chirita, M.; Ahmed, G.; Dutta, K.; Kalita, K.; Lehmann, A.; Böhm, M.; Schwarz, K.; Orth, H.; Brinkmann, K.-Th.

    2017-08-01

    The barrel-Time-of-Flight subdetector is one of the outer layers of the multi-layer design of the \\panda target spectrometer. It is designed with a minimal material budget in mind mainly consisting of 90×30×5 mm3 thin plastic scintillator tiles read out on each end by a serial connection of 4 SiPMs. 120 such tiles are placed on 16 2460 × 180 mm2 PCB boards forming a barrel covering an azimuthal angle from 22.5o to 150o. The detector is designed to achieve a time resolution below σ< 100 ps which allows to distinguish events in the constant stream of hits, as well as particle identification below the Cherenkov threshold via the time-of-flight; simultaneously providing the interaction times of events. The current prototype achieved a time resolution of ~54 ps, well below the design goal.

  15. Use of Electroplated Chromium in Gun Barrels

    DTIC Science & Technology

    2006-05-01

    Temperature; oF S t r e s s R e t a i n e d ; % 50% swage 75% swage Residual stress retained following 2 hr furnace heating of 120mm M256 gun barrels... Swage Autofrettage LARGE CALIBER GUN BARREL STRENGTH Coating Process Temperature Limitations Autofrettage allows gun barrels to be lighter and

  16. Direct 3D Analyses Reveal Barrel-Specific Vascular Distribution and Cross-Barrel Branching in the Mouse Barrel Cortex.

    PubMed

    Wu, Jingpeng; Guo, Congdi; Chen, Shangbin; Jiang, Tao; He, Yong; Ding, Wenxiang; Yang, Zhongqin; Luo, Qingming; Gong, Hui

    2016-01-01

    Whether vascular distribution is spatially specific among cortical columns is a fundamental yet controversial question. Here, we have obtained 1-μm resolution 3D datasets that cover the whole mouse barrel cortex by combining Nissl staining with micro-optical sectioning tomography to simultaneously visualize individual cells and blood vessels, including capillaries. Pinpointing layer IV of the posteromedial barrel subfield, direct 3D reconstruction and quantitative analysis showed that (1) penetrating vessels preferentially locate in the interbarrel septa/barrel wall (75.1%) rather than the barrel hollows, (2) the branches of 70% penetrating vessels only reach the neighboring but not always all the neighboring barrels and the other 30% extend beyond the neighboring barrels and may provide cross-barrel blood supply or drainage, (3) the branches of 59.6% penetrating vessels reach all the neighboring barrels, while the rest only reach part of them, and (4) the length density of microvessels in the interbarrel septa/barrel wall is lower than that in the barrel hollows with a ratio of 0.92. These results reveal that the penetrating vessels and microvessels exhibit a barrel-specific organization, whereas the branches of penetrating vessels do not, which suggests a much more complex vascular distribution pattern among cortical columns than previously thought. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  17. 15 CFR 241.2 - Legal standard barrels.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.2 Legal standard barrels. (a) Any barrel..., other than cranberries, in section 1 of the standard-barrel law, or any barrel or a subdivision thereof... than cranberries, or a legal subdivision thereof. No other barrel or subdivision in barrel form is a...

  18. 15 CFR 241.2 - Legal standard barrels.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.2 Legal standard barrels. (a) Any barrel..., other than cranberries, in section 1 of the standard-barrel law, or any barrel or a subdivision thereof... than cranberries, or a legal subdivision thereof. No other barrel or subdivision in barrel form is a...

  19. 15 CFR 241.2 - Legal standard barrels.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., VEGETABLES AND OTHER DRY COMMODITIES, AND FOR CRANBERRIES § 241.2 Legal standard barrels. (a) Any barrel..., other than cranberries, in section 1 of the standard-barrel law, or any barrel or a subdivision thereof... than cranberries, or a legal subdivision thereof. No other barrel or subdivision in barrel form is a...

  20. The PANDA Barrel DIRC detector

    NASA Astrophysics Data System (ADS)

    Hoek, M.; Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Hohler, R.; Kalicy, G.; Kumawat, H.; Lehmann, D.; Lewandowski, B.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwarz, C.; Schwiening, J.; Traxler, M.; Zühlsdorf, M.; Dodokhov, V. Kh.; Britting, A.; Eyrich, W.; Lehmann, A.; Uhlig, F.; Düren, M.; Föhl, K.; Hayrapetyan, A.; Kröck, B.; Merle, O.; Rieke, J.; Cowie, E.; Keri, T.; Montgomery, R.; Rosner, G.; Achenbach, P.; Cardinali, M.; Lauth, W.; Sfienti, C.; Thiel, M.; Bühler, P.; Gruber, L.; Marton, J.; Suzuki, K.

    2014-12-01

    The PANDA experiment at the new Facility for Antiproton and Ion Research in Europe (FAIR) at GSI, Darmstadt, will study fundamental questions of hadron physics and QCD using high-intensity cooled antiproton beams with momenta between 1.5 and 15 GeV/c. Efficient Particle Identification for a wide momentum range and the full solid angle is required for reconstructing the various physics channels of the PANDA program. Hadronic Particle Identification in the barrel region of the detector will be provided by a DIRC counter. The design is based on the successful BABAR DIRC with important improvements, such as focusing optics and fast photon timing. Several of these improvements, including different radiator geometries and optics, were tested in particle beams at GSI and at CERN. The evolution of the conceptual design of the PANDA Barrel DIRC and the performance of complex prototypes in test beam campaigns will be discussed.

  1. Development of an advanced electromagnetic gun barrel

    NASA Astrophysics Data System (ADS)

    Hurn, T. W.; D'Aoust, J.; Sevier, L.; Johnson, R.; Wesley, J.

    1993-01-01

    An advanced EM gun (AEMG) barrel was developed for the USAF Wright Laboratory to repetitively accelerate large-mass projectiles. The AEMG barrel employed 5-m rails, had a 50 mm square bore, and was designed to operate at a peak current of 1.5 MA (bore pressure 25 ksi). Key technical achievements included (1) an efficient barrel containment structure that weighs approximately 25 percent of a similarly rated clamped barrel, (2) an insulator material that retains surface resistivity after repeated firings, and (3) a high-velocity water cooling system designed to remove a peak heat flux of 5 MJ/sq m per shot. The AEMG barrel's thermal management system employed a 500 psi blowdown system that generated high velocity coolant flow rates in five axial coolant channels within each rail. Innovative fabrication processes were used to develop the barrel. A 2-m prototype of the AEMG barrel was tested in the General Atomics 4 MJ EM launcher test facility.

  2. Monolithic spectrometer

    DOEpatents

    Rajic, S.; Egert, C.M.; Kahl, W.K.; Snyder, W.B. Jr.; Evans, B.M. III; Marlar, T.A.; Cunningham, J.P.

    1998-05-19

    A monolithic spectrometer is disclosed for use in spectroscopy. The spectrometer is a single body of translucent material with positioned surfaces for the transmission, reflection and spectral analysis of light rays. 6 figs.

  3. Monolithic spectrometer

    DOEpatents

    Rajic, Slobodan; Egert, Charles M.; Kahl, William K.; Snyder, Jr., William B.; Evans, III, Boyd M.; Marlar, Troy A.; Cunningham, Joseph P.

    1998-01-01

    A monolithic spectrometer is disclosed for use in spectroscopy. The spectrometer is a single body of translucent material with positioned surfaces for the transmission, reflection and spectral analysis of light rays.

  4. Prototyping the PANDA Barrel DIRC

    NASA Astrophysics Data System (ADS)

    Schwarz, C.; Kalicy, G.; Dzhygadlo, R.; Gerhardt, A.; Götzen, K.; Hohler, R.; Kumawat, H.; Lehmann, D.; Lewandowski, B.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwiening, J.; Traxler, M.; Zühlsdorf, M.; Dodokhov, V. Kh.; Britting, A.; Eyrich, W.; Lehmann, A.; Uhlig, F.; Düren, M.; Föhl, K.; Hayrapetyan, A.; Kröck, B.; Merle, O.; Rieke, J.; Cowie, E.; Keri, T.; Montgomery, R.; Rosner, G.; Achenbach, P.; Cardinali, M.; Hoek, M.; Lauth, W.; Sfienti, C.; Thiel, M.; Bühler, P.; Gruber, L.; Marton, J.; Suzuki, K.

    2014-12-01

    The design of the Barrel DIRC detector for the future PANDA experiment at FAIR contains several important improvements compared to the successful BABAR DIRC, such as focusing and fast timing. To test those improvements as well as other design options a prototype was build and successfully tested in 2012 with particle beams at CERN. The prototype comprises a radiator bar, focusing lens, mirror, and a prism shaped expansion volume made of synthetic fused silica. An array of micro-channel plate photomultiplier tubes measures the location and arrival time of the Cherenkov photons with sub-nanosecond resolution. The development of a fast reconstruction algorithm allowed to tune construction details of the detector setup with test beam data and Monte-Carlo simulations.

  5. Excitatory neuronal connectivity in the barrel cortex

    PubMed Central

    Feldmeyer, Dirk

    2012-01-01

    Neocortical areas are believed to be organized into vertical modules, the cortical columns, and the horizontal layers 1–6. In the somatosensory barrel cortex these columns are defined by the readily discernible barrel structure in layer 4. Information processing in the neocortex occurs along vertical and horizontal axes, thereby linking individual barrel-related columns via axons running through the different cortical layers of the barrel cortex. Long-range signaling occurs within the neocortical layers but also through axons projecting through the white matter to other neocortical areas and subcortical brain regions. Because of the ease of identification of barrel-related columns, the rodent barrel cortex has become a prototypical system to study the interactions between different neuronal connections within a sensory cortical area and between this area and other cortical as well subcortical regions. Such interactions will be discussed specifically for the feed-forward and feedback loops between the somatosensory and the somatomotor cortices as well as the different thalamic nuclei. In addition, recent advances concerning the morphological characteristics of excitatory neurons and their impact on the synaptic connectivity patterns and signaling properties of neuronal microcircuits in the whisker-related somatosensory cortex will be reviewed. In this context, their relationship between the structural properties of barrel-related columns and their function as a module in vertical synaptic signaling in the whisker-related cortical areas will be discussed. PMID:22798946

  6. MISR Level 1A Products

    Atmospheric Science Data Center

    2013-04-01

    ... MISR Level 1A Products Level 1A Engineering Data File Type 1 and Level 1A Navigation Data Processing ... Product Specification Rev K  (PDF). Transparent software rebuild with Irix 6.5.2 OS. F01_0007 (FM_ENG), ...

  7. Correlation spectrometer

    DOEpatents

    Sinclair, Michael B [Albuquerque, NM; Pfeifer, Kent B [Los Lunas, NM; Flemming, Jeb H [Albuquerque, NM; Jones, Gary D [Tijeras, NM; Tigges, Chris P [Albuquerque, NM

    2010-04-13

    A correlation spectrometer can detect a large number of gaseous compounds, or chemical species, with a species-specific mask wheel. In this mode, the spectrometer is optimized for the direct measurement of individual target compounds. Additionally, the spectrometer can measure the transmission spectrum from a given sample of gas. In this mode, infrared light is passed through a gas sample and the infrared transmission signature of the gasses present is recorded and measured using Hadamard encoding techniques. The spectrometer can detect the transmission or emission spectra in any system where multiple species are present in a generally known volume.

  8. 15 CFR 241.2 - Legal standard barrels.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... having the dimensions specified for a standard barrel for fruits, vegetables, and other dry commodities... form or dimensions, is a legal standard barrel for fruits, vegetables, or other dry commodities other... having the dimensions specified for a standard barrel for cranberries in section 1 of the standard-barrel...

  9. 15 CFR 241.2 - Legal standard barrels.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... having the dimensions specified for a standard barrel for fruits, vegetables, and other dry commodities... form or dimensions, is a legal standard barrel for fruits, vegetables, or other dry commodities other... having the dimensions specified for a standard barrel for cranberries in section 1 of the standard-barrel...

  10. Multidimensional spectrometer

    SciTech Connect

    Zanni, Martin Thomas; Damrauer, Niels H.

    2010-07-20

    A multidimensional spectrometer for the infrared, visible, and ultraviolet regions of the electromagnetic spectrum, and a method for making multidimensional spectroscopic measurements in the infrared, visible, and ultraviolet regions of the electromagnetic spectrum. The multidimensional spectrometer facilitates measurements of inter- and intra-molecular interactions.

  11. Cold Rotary Forging of Small Caliber Gun Barrels

    DTIC Science & Technology

    1975-12-01

    COMPONENTS SUPPORTED. (1) 7.62mm M219 machine gun barrel (2) 7.62mm M134 mini gun ( Gau barrel) (3) .30 caliber machine gun barrel (4) 5.56=m MI6Al rifle ...barrel (5) 50 cal. M8C spotting rifle barrel (6) 7.62mm Ml4 National Match rifle bw’rel (7) other small arms weapon barrels K -. 1. FACILITIES SUPPORTED... rifle barrels was made in conjunction with the rotary forging process. From this, a purchase description was written and submitted for bid for a

  12. Schwarzschild spectrometer.

    PubMed

    Mouriz, M Dolores; Lago, Elena López; Prieto-Blanco, Xesús; González-Núñez, Héctor; de la Fuente, Raúl

    2011-06-01

    This is a proposal and description of a new spectrometer based on the Schwarzschild optical system. The proposed design contains two Schwarzschild optical systems. Light diverging from the spectrometer entrance slit is collimated by the first one; the collimated light beam hits a planar diffraction grating and the light dispersed from the grating is focused by the second system, which is concentric with the first. A very simple procedure obtains designs that are anastigmatic for the center of the slit and for a particular wavelength. A specific example shows the performance of this type of spectrometer.

  13. SCINTILLATION SPECTROMETER

    DOEpatents

    Bell, P.R.; Francis, J.E.

    1960-06-21

    A portable scintillation spectrometer is described which is especially useful in radio-biological studies for determining the uptake and distribution of gamma -emitting substances in tissue. The spectrometer includes a collimator having a plurality of apertures that are hexagonal in cross section. Two crystals are provided: one is activated to respond to incident rays from the collimator; the other is not activated and shields the first from external radiation.

  14. GIFTS SM EDU Level 1B Algorithms

    NASA Technical Reports Server (NTRS)

    Tian, Jialin; Gazarik, Michael J.; Reisse, Robert A.; Johnson, David G.

    2007-01-01

    The Geosynchronous Imaging Fourier Transform Spectrometer (GIFTS) SensorModule (SM) Engineering Demonstration Unit (EDU) is a high resolution spectral imager designed to measure infrared (IR) radiances using a Fourier transform spectrometer (FTS). The GIFTS instrument employs three focal plane arrays (FPAs), which gather measurements across the long-wave IR (LWIR), short/mid-wave IR (SMWIR), and visible spectral bands. The raw interferogram measurements are radiometrically and spectrally calibrated to produce radiance spectra, which are further processed to obtain atmospheric profiles via retrieval algorithms. This paper describes the GIFTS SM EDU Level 1B algorithms involved in the calibration. The GIFTS Level 1B calibration procedures can be subdivided into four blocks. In the first block, the measured raw interferograms are first corrected for the detector nonlinearity distortion, followed by the complex filtering and decimation procedure. In the second block, a phase correction algorithm is applied to the filtered and decimated complex interferograms. The resulting imaginary part of the spectrum contains only the noise component of the uncorrected spectrum. Additional random noise reduction can be accomplished by applying a spectral smoothing routine to the phase-corrected spectrum. The phase correction and spectral smoothing operations are performed on a set of interferogram scans for both ambient and hot blackbody references. To continue with the calibration, we compute the spectral responsivity based on the previous results, from which, the calibrated ambient blackbody (ABB), hot blackbody (HBB), and scene spectra can be obtained. We now can estimate the noise equivalent spectral radiance (NESR) from the calibrated ABB and HBB spectra. The correction schemes that compensate for the fore-optics offsets and off-axis effects are also implemented. In the third block, we developed an efficient method of generating pixel performance assessments. In addition, a

  15. Multi-rail barrel design and performance

    NASA Astrophysics Data System (ADS)

    Maas, Brian L.; Bauer, David P.; Challita, Antonios

    1993-01-01

    Railgun barrels containing multiple isolated rail pairs can be used to control armature current distribution and/or to obtain independent circuits for use with specialized power supplies. Armature current control can be used to effectively distribute acceleration forces for improved projectile launch. Independent rail 'load' circuits are attractive for use with some power supplies such as a polyphase compulsator. We have built and tested a 30 mm barrel containing three distinct rail pairs. These three rail pairs were powered by separate power supplies. This paper describes issues associated with multi-rail barrel design and our band design and performance. Rail alignment, isolation, and construction are described. The effect of multiple rail pairs on the effective inductance gradient of the band is described and test results are provided.

  16. Observations of a solar storm from the stratosphere: The BARREL Mission

    NASA Astrophysics Data System (ADS)

    Halford, Alexa

    2016-07-01

    During the Balloon Array for Radiation belt Relativistic Electron Losses (BARREL) second campaign, BARREL observed with a single primary instrument, a 3"x3" NaI spectrometer measuring 20 keV - 10 MeV X-rays [Woodger et al 2015 JGR], portions of an entire solar storm. This very small event, in terms of geomagnetic activity, or one of the largest of the current solar cycle, in terms of solar energetic particle events, has given us a very clear set of observations of the response of the day side magnetosphere to the arrival of an interplanetary coronal mass ejection shock. The BARREL mission of opportunity working in tandem with the Van Allen Probes was designed to study the loss of radiation belt electrons to the ionosphere and upper atmosphere. However BARREL is able to see X-rays from a multitude of sources. During the second campaign, the Sun produced, and BARREL observed, an X-class flare [McGregor et al in prep.]. This was followed by BARREL observations of X-rays, gamma-rays, and directly injected protons from the solar energetic particle (SEP) event associated with the eruption from the Sun while simultaneously the Van Allen Probes observed the SEP protons in the inner magnetosphere [Halford et al 2016 submitted JGR]. Two days later the shock generated by the interplanetary coronal mass ejection (ICME-shock) hit the Earth while BARREL was in conjunction with the Van Allen Probes and GOES [Halford et al 2015 JGR]. Although this was a Mars directed CME and the Earth only received a glancing blow [Möstl et al 2015 Nat. Commun., Mays et al 2015 ApJ], the modest compression led to the formation of ultra low frequency (ULF) waves, electromagnetic ion cyclotron (EMIC) waves, and very low frequency (VLF) whistler mode waves [Halford and Mann 2016 submitted to JGR]. The combination of these waves and the enhancement of the local particle population led to precipitation of electrons remotely observed by BARREL. This was not a Halloween, Bastille Day, or one of the now

  17. Rain Barrels: A Catalyst for Change?

    ERIC Educational Resources Information Center

    Bakacs, Michele E.; Haberland, Mike; Mangiafico, Salvatore S.; Winquist, Aileen; Obropta, Christopher C.; Boyajian, Amy; Mellor, Sara

    2013-01-01

    Over the past 4 years, rain barrel programming for residents has been implemented in both Northern Virginia and New Jersey as a method for educating the public about stormwater management and water conservation. Program participants demonstrated a significant increase in knowledge of water resource issues. Follow-up surveys showed 58% of New…

  18. DIOXIN FORMATION: THE BURN BARREL STUDY

    EPA Science Inventory

    The paper reports results from tests designed to examine some of the factors influencing the emissions of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDDs/Fs) from burn barrels. Results from PCDDs/Fs and polychlorinated biphenyls (PCBs) are reported, al...

  19. Rain Barrels: A Catalyst for Change?

    ERIC Educational Resources Information Center

    Bakacs, Michele E.; Haberland, Mike; Mangiafico, Salvatore S.; Winquist, Aileen; Obropta, Christopher C.; Boyajian, Amy; Mellor, Sara

    2013-01-01

    Over the past 4 years, rain barrel programming for residents has been implemented in both Northern Virginia and New Jersey as a method for educating the public about stormwater management and water conservation. Program participants demonstrated a significant increase in knowledge of water resource issues. Follow-up surveys showed 58% of New…

  20. 49 CFR 178.510 - Standards for wooden barrels.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PACKAGINGS Non-bulk Performance-Oriented Packaging Standards § 178.510 Standards for wooden barrels. (a) The... intended use of the barrel. (3) Staves and heads must be sawn or cleft with the grain so that no...

  1. Barrel lateral force modeling of a curved EM railgun

    NASA Astrophysics Data System (ADS)

    Chu, Szu H.

    1993-01-01

    This report presents a mathematical model to assess the normal barrel-projectile interaction forces arising from the barrel curvature of an electromagnetic railgun. It shows the significant relationships among the main parameters, such as the Lorentz force, the projectile displacement, velocity and the barrel curvature. Equations are derived to make quick computations and parametric relations are expressed explicitly. In a sample computation, the results show a large normal force would be generated by a sufficiently curved barrel.

  2. Spectrometer gun

    DOEpatents

    Waechter, D.A.; Wolf, M.A.; Umbarger, C.J.

    1981-11-03

    A hand-holdable, battery-operated, microprocessor-based spectrometer gun is described that includes a low-power matrix display and sufficient memory to permit both real-time observation and extended analysis of detected radiation pulses. Universality of the incorporated signal processing circuitry permits operation with various detectors having differing pulse detection and sensitivity parameters.

  3. Spectrometer gun

    DOEpatents

    Waechter, David A.; Wolf, Michael A.; Umbarger, C. John

    1985-01-01

    A hand-holdable, battery-operated, microprocessor-based spectrometer gun includes a low-power matrix display and sufficient memory to permit both real-time observation and extended analysis of detected radiation pulses. Universality of the incorporated signal processing circuitry permits operation with various detectors having differing pulse detection and sensitivity parameters.

  4. HISS spectrometer

    SciTech Connect

    Greiner, D.E.

    1984-11-01

    This talk describes the Heavy Ion Spectrometer System (HISS) facility at the Lawrence Berkeley Laboratory's Bevalac. Three completed experiments and their results are illustrated. The second half of the talk is a detailed discussion of the response of drift chambers to heavy ions. The limitations of trajectory measurement over a large range in incident particle charge are presented.

  5. The Spectrometer

    ERIC Educational Resources Information Center

    Greenslade, Thomas B., Jr.

    2012-01-01

    In the fall of 1999 I was shown an Ocean Optics spectrometer-in-the-computer at St. Patricks College at Maynooth, Ireland, and thought that I had seen heaven. Of course, it could not resolve the sodium D-lines (I had done that many years before with a homemade wire diffraction grating), and I began to realize that inside was some familiar old…

  6. The Spectrometer

    NASA Astrophysics Data System (ADS)

    Greenslade, Thomas B.

    2012-03-01

    In the fall of 1999 I was shown an Ocean Optics spectrometer-in-the-computer at St. Patricks College at Maynooth, Ireland, and thought that I had seen heaven. Of course, it could not resolve the sodium D-lines (I had done that many years before with a homemade wire diffraction grating ), and I began to realize that inside was some familiar old technology. In this paper I would like to discuss its ancestors.

  7. The Spectrometer

    ERIC Educational Resources Information Center

    Greenslade, Thomas B., Jr.

    2012-01-01

    In the fall of 1999 I was shown an Ocean Optics spectrometer-in-the-computer at St. Patricks College at Maynooth, Ireland, and thought that I had seen heaven. Of course, it could not resolve the sodium D-lines (I had done that many years before with a homemade wire diffraction grating), and I began to realize that inside was some familiar old…

  8. Barrel calorimeter of the CMD-3 detector

    SciTech Connect

    Shebalin, V. E. Anisenkov, A. V.; Aulchenko, V. M.; Bashtovoy, N. S.; Epifanov, D. A.; Epshteyn, L. B.; Grebenuk, A. A.; Ignatov, F. V.; Erofeev, A. L.; Kovalenko, O. A.; Kozyrev, A. N.; Kuzmin, A. S.; Logashenko, I. B.; Mikhailov, K. Yu.; Razuvaev, G. P.; Ruban, A. A.; Shwartz, B. A.; Talyshev, A. A.; Titov, V. M.; Yudin, Yu. V.

    2015-12-15

    The structure of the barrel calorimeter of the CMD-3 detector is presented in this work. The procedure of energy calibration of the calorimeter and the method of photon energy restoration are described. The distinctive feature of this barrel calorimeter is its combined structure; it is composed of two coaxial subsystems: a liquid xenon calorimeter and a crystalline CsI calorimeter. The calorimeter spatial resolution of the photon conversion point is about 2 mm, which corresponds to an angular resolution of ∼6 mrad. The energy resolution of the calorimeter is about 8% for photons with energy of 200 MeV and 4% for photons with energy of 1 GeV.

  9. Barrel cortex and whisker-mediated behaviors.

    PubMed

    Brecht, Michael

    2007-08-01

    Neural networks of the rodent barrel cortex are particularly tractable for developing a quantitative understanding of response transformations in a cortical column. A column in barrel cortex consists of approximately 10 compartments. Two thalamic input pathways, a sensory lemniscal one and sensorimotor paralemniscal one, are transformed to approximately 7 population outputs, each with distinct spatiotemporal response characteristics. Granular and supragranular layers are sites of segregated processing in lemniscal and paralemniscal pathways, whereas infragranular layers are sites of intracolumnar, lemniscal/paralemniscal integration. Individual thalamocortical connections are relatively weak, and a considerable fraction of thalamocortical afferents contributes to each sensory response. Intracortically, relatively few but strong synaptic connections contribute to sensory responses, and responses are rapidly terminated by inhibition. Overall cortical population activity is very low. Whiskers mediate a wide range of behaviors and many natural tactile behaviors occur very rapidly. Vibrissal object recognition can be size invariant and motion invariant and is based on the tactile 'Gestaltwahrnehmung' of shape.

  10. POLDER level-1 processing algorithms

    NASA Astrophysics Data System (ADS)

    Hagolle, Olivier; Guerry, Agnes; Cunin, Laurent; Millet, Bruno; Perbos, Jacqueline; Laherrere, Jean-Marc; Bret-Dibat, Thierry; Poutier, Laurent

    1996-06-01

    POLDER (polarization and directionality of the Earth reflectances) is a French instrument that will be flown on- board ADEOS (advanced earth observing satellite) polar orbiting satellite, scheduled to be launched in August 1996. POLDER is a multispectral imaging radiometer/polarimeter designed to collect global and repetitive observations of the solar radiation reflected by the Earth/atmosphere system, with a wide field of view (2400 km) and a moderate geometric resolution (6 km). The instrument concept is based on telecentric optics, on a rotating wheel carrying 15 spectral filters and polarizers, and on a bidimensional CCD detector array. In addition to the classical measurement and mapping characteristics of a narrow-band imaging radiometer, POLDER has a unique ability to measure polarized reflectances at three different polarization angles (for three of its eight visible and near-infrared spectral bands), and to observe target reflectances from 14 different viewing directions during a single satellite pass. All the data transmitted by POLDER are processed in the POLDER Processing Centre. Level 1 products include geometrically and radiometrically corrected data, level 2 products are elementary geophysical products created from a single satellite pass, and level 3 products are geophysical synthesis from several passes of the satellite. This paper presents the radiometrical and geometrical algorithms of the level 1 processing: new algorithms developed for the removal of sensor artefacts (smearing, stray light), for the radiometrical mode inversion (normalized radiance and polarization parameter extraction), and for the geometrical projection of the data on a unique grid are explained.

  11. Performance of prototypes for the PANDA barrel EMC

    NASA Astrophysics Data System (ADS)

    Bremer, D. A.; Eissner, T.; Drexler, P.; Moritz, M.; Novotny, R. W.; PANDA Collaboration

    2015-02-01

    The PANDA experiment will be part of the future Facility for Antiproton and Ion Research (FAIR) and aims for the study of strong interaction within the charm sector via antiproton proton collisions up to antiproton momenta of 15 GeV/c. Reflecting the variety of the physics program the PANDA detector is designed as a multi-purpose detector able to perform tracking, calorimetry and particle identification with nearly complete coverage of the solid angle. The Electromagnetic Calorimeter (EMC) contained inside its Target Spectrometer is based on cooled PbWO4 scintillator crystals. In order to ensure an excellent performance throughout the large dynamic range of photon/electron energies ranging from a few MeV up to 15 GeV an extensive prototyping phase is mandatory. This contribution describes the measured response of the EMC barrel part prototype PROTO60 at the largest design energy to secondary beams provided by the SPS at CERN. In addition to PROTO60 a tracking station was deployed, providing precise position information of the 15 GeV/c positrons. For calibration purposes a 150 GeV/c muon beam and cosmic radiation, in combination with estimations from GEANT4 simulations were used. The obtained performance concerning energy, position and time information is presented.

  12. MASS SPECTROMETER

    DOEpatents

    White, F.A.

    1960-08-23

    A mass spectrometer is designed with a first adjustable magnetic field for resolving an ion beam into beams of selected masses, a second adjustable magnetic field for further resolving the ion beam from the first field into beams of selected masses, a thin foil disposed in the path of the beam between the first and second magnets to dissociate molecular ions incident thereon, an electrostatic field for further resolving the ion beam from the second field into beams of selected masses, and a detector disposed adjacent to the electrostatic field to receive the ion beam.

  13. Computer Spectrometers

    NASA Astrophysics Data System (ADS)

    Dattani, Nikesh S.

    2017-06-01

    Ideally, the cataloguing of spectroscopic linelists would not demand laborious and expensive experiments. Whatever an experiment might achieve, the same information would be attainable by running a calculation on a computer. Kolos and Wolniewicz were the first to demonstrate that calculations on a computer can outperform even the most sophisticated molecular spectroscopic experiments of the time, when their 1964 calculations of the dissociation energies of H_2 and D_{2} were found to be more than 1 cm^{-1} larger than the best experiments by Gerhard Herzberg, suggesting the experiment violated a strict variational principle. As explained in his Nobel Lecture, it took 5 more years for Herzberg to perform an experiment which caught up to the accuracy of the 1964 calculations. Today, numerical solutions to the Schrödinger equation, supplemented with relativistic and higher-order quantum electrodynamics (QED) corrections can provide ro-vibrational spectra for molecules that we strongly believe to be correct, even in the absence of experimental data. Why do we believe these calculated spectra are correct if we do not have experiments against which to test them? All evidence seen so far suggests that corrections due to gravity or other forces are not needed for a computer simulated QED spectrum of ro-vibrational energy transitions to be correct at the precision of typical spectrometers. Therefore a computer-generated spectrum can be considered to be as good as one coming from a more conventional spectrometer, and this has been shown to be true not just for the H_2 energies back in 1964, but now also for several other molecules. So are we at the stage where we can launch an array of calculations, each with just the atomic number changed in the input file, to reproduce the NIST energy level databases? Not quite. But I will show that for the 6e^- molecule Li_2, we have reproduced the vibrational spacings to within 0.001 cm^{-1} of the experimental spectrum, and I will

  14. Results from the SLD barrel CRID detector

    SciTech Connect

    Abe, K.; Antilogus, P. |; Aston, D.

    1993-11-01

    We report on operational experience with and experimental performance of the SLD barrel Cherenkov Ring Imaging Detector from the 1992 and 1993 physics runs. The liquid (C{sub 6}F{sub 14}) and gas (C{sub 5}F{sub 12}) radiator recirculation systems have performed well, and the drift gas supply system has operated successfully with TMAE for three years. Cherenkov rings have been observed from both the liquid and gas radiators. The number and angular resolution of Cherenkov photons have been measured, and found to be close to design specifications.

  15. Real-time monitoring of barrel thickness and barrel/screw separation using ultrasound

    NASA Astrophysics Data System (ADS)

    Jen, Cheng-Kuei; Zun, Zhigang; Kobayashi, Makiko

    2005-03-01

    Ultrasonic sensors together with a fast data acquisition system have been used to monitor the barrel thickness and barrel/screw separation during low-density polyethylene as well as high-density polyethylene extrusion in 30 mm and 50 mm twin-screw extruders. The sensors include sol-gel sprayed high temperature (HT) piezoelectric thick ceramic film ultrasonic transducers (UTs), stand-alone HTUTs and air-cooled buffer rod type sensors consisting of a room temperature UT and a non-clad or clad buffer rod to which the room temperature UT is attached. The installation and use of these sensors are non-intrusive to the extruder and non-destructive to the polymers being processed. This study has demonstrated the capability of appropriately designed ultrasonic sensors in monitoring the barrel and screw integrity at the melting, mixing and pumping zones of the extruder via barrel or flange. The merits and limitations of these sensors are discussed. The measurement speed and analysis of the sensitivity for quantitative wear measurements are also presented.

  16. 1. EXTERIOR, SIDE OF PICKLE BARREL RESTAURANT AND ADJOINING STORE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR, SIDE OF PICKLE BARREL RESTAURANT AND ADJOINING STORE - Silverton Historic District, East Thirteenth & Green Streets (Commercial Building), East Thirteenh & Green Streets, Silverton, San Juan County, CO

  17. Status of the PANDA Barrel DIRC

    NASA Astrophysics Data System (ADS)

    Kalicy, G.; Kumawat, H.; Schwiening, J.; Dzhygadlo, R.; Gerhardt, A.; Hohler, R.; Lehmann, D.; Lewandowski, B.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwarz, C.; Traxler, M.; Zühlsdorf, M.; Dodokhov, V. Kh; Vodopianov, A.; Britting, A.; Eyrich, W.; Lehmann, A.; Uhlig, F.; Düren, M.; Föhl, K.; Hayrapetyan, A.; Koch, P.; Kröck, B.; Merle, O.; Cowie, E.; Keri, T.; Montgomery, R.; Rosner, G.; Seitz, B.; Achenbach, P.; Cardinali, M.; Hoek, M.; Sfienti, C.; Thiel, M.; Ugur, C.; Bühler, P.; Gruber, L.; Marton, J.; Suzuki, K.; Widmann, E.; The PANDA Cherenkov Group

    2014-05-01

    The PANDA experiment at the future Facility for Antiproton and Ion Research in Europe GmbH (FAIR) at GSI, Darmstadt will study fundamental questions of hadron physics and QCD using high-intensity cooled antiproton beams with momenta between 1.5 and 15 GeV/c. Hadronic PID in the barrel region of the PANDA detector will be provided by a DIRC (Detection of Internally Reflected Cherenkov light) counter. The design is based on the successful BABAR DIRC with several key improvements, such as fast photon timing and a compact imaging region. Detailed Monte Carlo simulation studies were performed for DIRC designs based on narrow bars or wide plates with a variety of focusing solutions. The performance of each design was characterized in terms of photon yield and single photon Cherenkov angle resolution and a maximum likelihood approach was used to determine the π/K separation. Selected design options were implemented in prototypes and tested with hadronic particle beams at GSI and CERN. This article describes the status of the design and R&D for the PANDA Barrel DIRC detector, with a focus on the performance of different DIRC designs in simulation and particle beams.

  18. Parametric modeling of zoom lens barrels

    NASA Astrophysics Data System (ADS)

    Pierce, Charles W.

    2001-12-01

    Today's customer requires zoom lens designs that are compact, inexpensive, and at six-sigma quality levels. While incorporating these customer requirements, a design team must often work within compressed design cycles and minimal product development budgets. These customer and project constraints, coupled with the inherent complexity of a zoom lens module, force the design team to try new and innovative techniques to deliver their products. This paper presents the methods used to develop lens barrels for several zoom lens module projects at Eastman Kodak Company. The lens barrel, a critical interface between the mechanical and optical systems, presented a technical barrier from both an engineering analysis and manufacturing perspective. The method used to overcome these barriers consisted of identifying several key functional parameters, creating a parameter-driven 3-D solid model in a commercially available CAD system, and then using the model to make iterative, data-driven design decisions while leveraging the model to create engineering drawings and the necessary prototypes and production tooling. As a result, the designs were able to meet their size, cost, and design cycle time requirements while realizing a better than anticipated first pass yield and quality level.

  19. Level-1C Product from AIRS: Principal Component Filtering

    NASA Technical Reports Server (NTRS)

    Manning, Evan M.; Jiang, Yibo; Aumann, Hartmut H.; Elliott, Denis A.; Hannon, Scott

    2012-01-01

    The Atmospheric Infrared Sounder (AIRS), launched on the EOS Aqua spacecraft on May 4, 2002, is a grating spectrometer with 2378 channels in the range 3.7 to 15.4 microns. In a grating spectrometer each individual radiance measurement is largely independent of all others. Most measurements are extremely accurate and have very low noise levels. However, some channels exhibit high noise levels or other anomalous behavior, complicating applications needing radiances throughout a band, such as cross-calibration with other instruments and regression retrieval algorithms. The AIRS Level-1C product is similar to Level-1B but with instrument artifacts removed. This paper focuses on the "cleaning" portion of Level-1C, which identifies bad radiance values within spectra and produces substitute radiances using redundant information from other channels. The substitution is done in two passes, first with a simple combination of values from neighboring channels, then with principal components. After results of the substitution are shown, differences between principal component reconstructed values and observed radiances are used to investigate detailed noise characteristics and spatial misalignment in other channels.

  20. Level-1C Product from AIRS: Principal Component Filtering

    NASA Technical Reports Server (NTRS)

    Manning, Evan M.; Jiang, Yibo; Aumann, Hartmut H.; Elliott, Denis A.; Hannon, Scott

    2012-01-01

    The Atmospheric Infrared Sounder (AIRS), launched on the EOS Aqua spacecraft on May 4, 2002, is a grating spectrometer with 2378 channels in the range 3.7 to 15.4 microns. In a grating spectrometer each individual radiance measurement is largely independent of all others. Most measurements are extremely accurate and have very low noise levels. However, some channels exhibit high noise levels or other anomalous behavior, complicating applications needing radiances throughout a band, such as cross-calibration with other instruments and regression retrieval algorithms. The AIRS Level-1C product is similar to Level-1B but with instrument artifacts removed. This paper focuses on the "cleaning" portion of Level-1C, which identifies bad radiance values within spectra and produces substitute radiances using redundant information from other channels. The substitution is done in two passes, first with a simple combination of values from neighboring channels, then with principal components. After results of the substitution are shown, differences between principal component reconstructed values and observed radiances are used to investigate detailed noise characteristics and spatial misalignment in other channels.

  1. 27 CFR 25.141 - Barrels and kegs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Barrels and kegs. 25.141 Section 25.141 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Marks, Brands, and Labels § 25.141 Barrels and kegs. (a) General...

  2. Beam test of the SDC barrel EM calorimeter test module

    SciTech Connect

    Balka, L.; Guarino, V.; Hill, N.

    1994-05-01

    The SDC barrel electromagnetic calorimeter test module was exposed to beams of high energy pions and electrons in the MP9 test beam at Fermilab in the fall of 1991. Data were collected on resolution, light yield, signal timing and hermiticity. These data demonstrated that the design met the specifications for the barrel electromagnetic calorimeter of the Solenoidal Detector collaboration (SDC).

  3. 27 CFR 25.144 - Rebranding barrels and kegs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Rebranding barrels and kegs. 25.144 Section 25.144 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Marks, Brands, and Labels § 25.144 Rebranding barrels and...

  4. The PHENIX Muon Trigger Upgrade Level-1 Trigger System

    NASA Astrophysics Data System (ADS)

    Lajoie, John; Kempel, Todd

    2010-02-01

    The PHENIX Muon Trigger Upgrade adds a set of Level-1 trigger detectors to the existing muon spectrometers and will enhance the ability of the experiment to pursue a rich program of spin physics in polarized proton collisions. The upgrade will allow the experiment to select high momentum muons from the decay of W bosons and reject both beam-associated and low-momentum collision background, enabling the study of quark and antiquark polarization in the proton. The Muon Trigger Upgrade will add momentum and timing information to the present muon Level-1 trigger, which only makes use of tracking in the PHENIX muon identifier (MuID) panels. Signals from new Resistive Plate Chambers (RPCs) and re-instrumented planes in the existing muon tracking (MuTr) chambers will provide momentum and timing information for the new Level-1 trigger. An RPC timing resolution of ˜2 ns will permit rejection of beam related backgrounds while tracking information from the RPCs and MuTr station will be used by the trigger to select events with high momentum muon candidates. The RPC and MuTr hit information will be sent by optical fibers to a set of Level-1 trigger processors that will make use of cutting edge FPGA technology to provide very high data densities in a compact form factor. The layout of the upgrade, details of the Level-1 electronics and trigger algorithm development will be presented. )

  5. The structure of the β-barrel assembly machinery complex

    SciTech Connect

    Bakelar, Jeremy; Buchanan, Susan K.; Noinaj, Nicholas

    2016-01-08

    β-Barrel outer membrane proteins (OMPs) are found in the outer membranes of Gram-negative bacteria and are essential for nutrient import, signaling, and adhesion. A 200-kilodalton five-component complex called the β-barrel assembly machinery (BAM) complex has been implicated in the biogenesis of OMPs. In this paper, we report the structure of the BAM complex from Escherichia coli, revealing that binding of BamCDE modulates the conformation of BamA, the central component, which may serve to regulate the BAM complex. The periplasmic domain of BamA was in a closed state that prevents access to the barrel lumen, which indicates substrate OMPs may not be threaded through the barrel during biogenesis. Finally and further, conformational shifts in the barrel domain lead to opening of the exit pore and rearrangement at the lateral gate.

  6. The structure of the β-barrel assembly machinery complex

    DOE PAGES

    Bakelar, Jeremy; Buchanan, Susan K.; Noinaj, Nicholas

    2016-01-08

    β-Barrel outer membrane proteins (OMPs) are found in the outer membranes of Gram-negative bacteria and are essential for nutrient import, signaling, and adhesion. A 200-kilodalton five-component complex called the β-barrel assembly machinery (BAM) complex has been implicated in the biogenesis of OMPs. In this paper, we report the structure of the BAM complex from Escherichia coli, revealing that binding of BamCDE modulates the conformation of BamA, the central component, which may serve to regulate the BAM complex. The periplasmic domain of BamA was in a closed state that prevents access to the barrel lumen, which indicates substrate OMPs may notmore » be threaded through the barrel during biogenesis. Finally and further, conformational shifts in the barrel domain lead to opening of the exit pore and rearrangement at the lateral gate.« less

  7. Recent results from the Crystal Barrel experiment

    SciTech Connect

    Not Available

    1991-10-09

    The Crystal Barrel experiment has been constructed and installed at the Low Energy Antiproton Ring (LEAR) at CERN. It has been fully operational since late 1989. In this talk, recent results of meson spectroscopy in p[bar p]-annihilations are presented. The main emphasis is on all-neutral annihilations, the study of the strange quark content of the proton, and the investigation of the decay mode of il particles. A 2[sup ++] resonance decaying into [pi][degrees][pi][degrees]at a mass of 1515 [plus minus] 10 MeV with a width of 120 [plus minus] 10 MeV has been seen in a 3[pi][degrees] final state.

  8. Recent results from the Crystal Barrel experiment

    SciTech Connect

    The Crystal Barrel Collaboration

    1991-10-09

    The Crystal Barrel experiment has been constructed and installed at the Low Energy Antiproton Ring (LEAR) at CERN. It has been fully operational since late 1989. In this talk, recent results of meson spectroscopy in p{bar p}-annihilations are presented. The main emphasis is on all-neutral annihilations, the study of the strange quark content of the proton, and the investigation of the decay mode of il particles. A 2{sup ++} resonance decaying into {pi}{degrees}{pi}{degrees}at a mass of 1515 {plus_minus} 10 MeV with a width of 120 {plus_minus} 10 MeV has been seen in a 3{pi}{degrees} final state.

  9. Analysis of gun barrel rifling twist

    NASA Astrophysics Data System (ADS)

    Sun, Jia; Chen, Guangsong; Qian, Linfang; Liu, Taisu

    2017-05-01

    Aiming at the problem of gun barrel rifling twist, the constraint relation between rifling and projectile is investigated. The constraint model of rifling and projectile is established and the geometric relation between the twist and the motion of projectile is analyzed. Based on the constraint model, according to the rotating band that is fired, the stress and the motion law of the rotating band in bore are analyzed. The effects to rotating band (double rotating band or wide driving band) caused by different rifling (rib rifling, increasing rifling and combined rifling) are also investigated. The model is demonstrated by several examples. The results of numerical examples and the constraint mode show that the uncertainty factors will be brought in the increasing rifling and combined rifling during the projectile move in the bore. According to the amplitude and the strength of the twist acting on rotating band, the steady property of rotational motion of the projectile, the rib rifling is a better choose.

  10. Globally intertwined evolutionary history of giant barrel sponges

    NASA Astrophysics Data System (ADS)

    Swierts, Thomas; Peijnenburg, Katja T. C. A.; de Leeuw, Christiaan A.; Breeuwer, Johannes A. J.; Cleary, Daniel F. R.; de Voogd, Nicole J.

    2017-09-01

    Three species of giant barrel sponge are currently recognized in two distinct geographic regions, the tropical Atlantic and the Indo-Pacific. In this study, we used molecular techniques to study populations of giant barrel sponges across the globe and assessed whether the genetic structure of these populations agreed with current taxonomic consensus or, in contrast, whether there was evidence of cryptic species. Using molecular data, we assessed whether giant barrel sponges in each oceanic realm represented separate monophyletic lineages. Giant barrel sponges from 17 coral reef systems across the globe were sequenced for mitochondrial (partial CO1 and ATP6 genes) and nuclear (ATPsβ intron) DNA markers. In total, we obtained 395 combined sequences of the mitochondrial CO1 and ATP6 markers, which resulted in 17 different haplotypes. We compared a phylogenetic tree constructed from 285 alleles of the nuclear intron ATPsβ to the 17 mitochondrial haplotypes. Congruent patterns between mitochondrial and nuclear gene trees of giant barrel sponges provided evidence for the existence of multiple reproductively isolated species, particularly where they occurred in sympatry. The species complexes in the tropical Atlantic and the Indo-Pacific, however, do not form separate monophyletic lineages. This rules out the scenario that one species of giant barrel sponge developed into separate species complexes following geographic separation and instead suggests that multiple species of giant barrel sponges already existed prior to the physical separation of the Indo-Pacific and tropical Atlantic.

  11. Software development for the P¯ANDA barrel DIRC

    NASA Astrophysics Data System (ADS)

    Dutta, Dipanwita; P¯ANDA Cherenkov Group

    2011-05-01

    The charged particle identification in the barrel region of the P¯ANDA detector in the future FAIR facility at GSI is planned with a very thin Cherenkov detector using the DIRC principle. Due to a very compact design of the barrel DIRC with focusing optics, the reconstruction of the Cherenkov angle is quite challenging. In this contribution, the possible reconstruction algorithm of the barrel DIRC will be discussed, with emphasis on the possibility to include the DIRC in the trigger decision and the correction of the chromatic dispersion with fast timing information.

  12. Transmembrane beta-barrel protein structure prediction

    NASA Astrophysics Data System (ADS)

    Randall, Arlo; Baldi, Pierre

    Transmembrane β-barrel (TMB) proteins are embedded in the outer membranes of mitochondria, Gram-negative bacteria, and chloroplasts. These proteins perform critical functions, including active ion-transport and passive nutrient intake. Therefore, there is a need for accurate prediction of secondary and tertiary structures of TMB proteins. A variety of methods have been developed for predicting the secondary structure and these predictions are very useful for constructing a coarse topology of TMB structure; however, they do not provide enough information to construct a low-resolution tertiary structure for a TMB protein. In addition, while the overall structural architecture is well conserved among TMB proteins, the amino acid sequences are highly divergent. Thus, traditional homology modeling methods cannot be applied to many putative TMB proteins. Here, we describe the TMBpro: a pipeline of methods for predicting TMB secondary structure, β-residue contacts, and finally tertiary structure. The tertiary prediction method relies on the specific construction rules that TMB proteins adhere to and on the predicted β-residue contacts to dramatically reduce the search space for the model building procedure.

  13. 18. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARRELS IN PLACE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARRELS IN PLACE TO BE USED AS PIPE TUNNELS. INEEL PHOTO NUMBER NRTS-59-925. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

  14. 16. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARREL BEING LOWERED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. CONSTRUCTION PROGRESS PHOTO SHOWING SURPLUS GUN BARREL BEING LOWERED INTO PLACE FOR USE AS PIPE TUNNEL. INEEL PHOTO NUMBER NRTS-59-709. - Idaho National Engineering Laboratory, Old Waste Calcining Facility, Scoville, Butte County, ID

  15. Finite element analysis of the SDC barrel and endcap calorimeters

    SciTech Connect

    Guarino, V.; Hill, N.; Nasiakta, J.

    1992-03-11

    In designing the SCD barrel and endcap calorimeters, the inter-module connecting forces must be known in order to determine the required size and number of connecting links between modules, and in order to understand how individual modules will be affected by these forces when assembled to form a full barrel and endcap. The connecting forces were found by analyzing three-dimensional Finite Element Models of both the barrel and endcap. This paper is divided into two parts, the first part will describe in detail the results of the barrel analysis and the second part will describe the results obtained from the endcap analysis. A similar approach was used in constructing the models for both analysis.

  16. 49 CFR 178.510 - Standards for wooden barrels.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR PACKAGINGS Non... of the barrel. (3) Staves and heads must be sawn or cleft with the grain so that no annual...

  17. Finite element analysis of the SDC barrel and endcap calorimeters

    SciTech Connect

    Guarino, V.; Hill, N.; Nasiakta, J.

    1992-03-11

    In designing the SCD barrel and endcap calorimeters, the inter-module connecting forces must be known in order to determine the required size and number of connecting links between modules, and in order to understand how individual modules will be affected by these forces when assembled to form a full barrel and endcap. The connecting forces were found by analyzing three-dimensional Finite Element Models of both the barrel and endcap. This paper is divided into two parts, the first part will describe in detail the results of the barrel analysis and the second part will describe the results obtained from the endcap analysis. A similar approach was used in constructing the models for both analysis.

  18. Interior view, barrel vaulted store room opening from the south ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view, barrel vaulted store room opening from the south side of the ground floors central east-west passage (PA-1622-A-51) looking northeast. - U. S. Naval Asylum, Biddle Hall, Gray's Ferry Avenue, Philadelphia, Philadelphia County, PA

  19. 8. VIEW NORTHWEST OF EAST ELEVATION SOUTH BARREL ARCH. NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW NORTHWEST OF EAST ELEVATION SOUTH BARREL ARCH. NOTE STONE WORK, 1920 CONCRETE REPAIRS, AND STEEL BRACES ADDED BY THE NATIONAL PARK SERVICE CIRCA 1962. - Chesapeake & Ohio Canal, Conococheague Creek Aqueduct, Milepost 99.80, Williamsport, Washington County, MD

  20. Barrel view from east end, looking toward swing span. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Barrel view from east end, looking toward swing span. - Pennsylvania & New Jersey Railroad, Delaware River Bridge, Spanning Delaware River, south of Betsy Ross Bridge (State Route 90), Philadelphia, Philadelphia County, PA

  1. Barrel view at east end of swing span. Pennsylvania ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Barrel view at east end of swing span. - Pennsylvania & New Jersey Railroad, Delaware River Bridge, Spanning Delaware River, south of Betsy Ross Bridge (State Route 90), Philadelphia, Philadelphia County, PA

  2. Barrel view at east end of verticallift span. Pennsylvania ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Barrel view at east end of vertical-lift span. - Pennsylvania & New Jersey Railroad, Delaware River Bridge, Spanning Delaware River, south of Betsy Ross Bridge (State Route 90), Philadelphia, Philadelphia County, PA

  3. Allen Auditorium attic looking from southeast corner. Wine barrels with ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Allen Auditorium attic looking from southeast corner. Wine barrels with scrap used for counterweight material for lift up walls no longer in use - Sheldon Jackson College, Richard H. Allen Memorial Hall, Lincoln Street, Sitka, Sitka Borough, AK

  4. Staining in firearm barrels after experimental contact shots.

    PubMed

    Schyma, C; Bauer, K; Brünig, J; Courts, C; Madea, B

    2017-04-01

    After contact shots to the head biological traces inside firearm barrels can be found. This study was conducted to simulate and to evaluate such staining. Five current handguns of four inch barrel length in the calibre .22 long rifle, 7.65mm Browning, 9mm Luger and .38 special were used to perform 24 contact shots on silicone coated, gelatine filled box models using the triple contrast method. The staining was documented by endoscopy and swabs gathered from both ends of the barrel were analysed by quantitative PCR. With the exception of the .22 revolver, all firearms showed distinct staining which decreased from the muzzle to the rear end of the barrel. The pattern was varied, showing droplets, elongated forms or stripes. In 14 of 24 shots, staining reached the chamber. The staining results were comparable to real suicide cases.

  5. 1. Exterior, corner, wall, and barrel of cannon used to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Exterior, corner, wall, and barrel of cannon used to protect corner of building from cart wheels. 1960. - Jefferson Barracks, Brick & Stone Powder Magazine, Jefferson Barracks, St. Louis County, MO

  6. 3. BARREL VIEW, LOOKING DOWN LENGTH OF BRIDGE, SHOWING MAKER'S ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. BARREL VIEW, LOOKING DOWN LENGTH OF BRIDGE, SHOWING MAKER'S PLATE, DECORATIVE SCROLLWORK AND URN FINIALS ON NORTHEAST PORTAL - "Forder" Pratt Through Truss Bridge, Spanning Maumee River at County Route 73, Antwerp, Paulding County, OH

  7. INTERIOR VIEW, DETAIL OF BARREL ROOF STRUCTURE, FACING NORTHEAST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW, DETAIL OF BARREL ROOF STRUCTURE, FACING NORTHEAST. - Southern Branch of the National Home for Disabled Volunteer Soldiers, Building 13, Harris Avenue at its intersection of Black Avenue and Woodfin Street, Hampton, Hampton, VA

  8. Neonatal lead exposure impairs development of rodent barrel field cortex

    PubMed Central

    Wilson, Mary Ann; Johnston, Michael V.; Goldstein, Gary W.; Blue, Mary E.

    2000-01-01

    Childhood exposure to low-level lead can permanently reduce intelligence, but the neurobiologic mechanism for this effect is unknown. We examined the impact of lead exposure on the development of cortical columns, using the rodent barrel field as a model. In all areas of mammalian neocortex, cortical columns constitute a fundamental structural unit subserving information processing. Barrel field cortex contains columnar processing units with distinct clusters of layer IV neurons that receive sensory input from individual whiskers. In this study, rat pups were exposed to 0, 0.2, 1, 1.5, or 2 g/liter lead acetate in their dam's drinking water from birth through postnatal day 10. This treatment, which coincides with the development of segregated columns in the barrel field, produced blood lead concentrations from 1 to 31 μg/dl. On postnatal day 10, the area of the barrel field and of individual barrels was measured. A dose-related reduction in barrel field area was observed (Pearson correlation = −0.740; P < 0.001); mean barrel field area in the highest exposure group was decreased 12% versus controls. Individual barrels in the physiologically more active caudoventral group were affected preferentially. Total cortical area measured in the same sections was not altered significantly by lead exposure. These data support the hypothesis that lead exposure may impair the development of columnar processing units in immature neocortex. We demonstrate that low levels of blood lead, in the range seen in many impoverished inner-city children, cause structural alterations in a neocortical somatosensory map. PMID:10805810

  9. Tropospheric Emission Spectrometer and Airborne Emission Spectrometer

    NASA Technical Reports Server (NTRS)

    Glavich, T.; Beer, R.

    1996-01-01

    The Tropospheric Emission Spectrometer (TES) is an instrument being developed for the NASA Earth Observing System Chemistry Platform. TES will measure the distribution of ozone and its precursors in the lower atmosphere. The Airborne Emission Spectrometer (AES) is an aircraft precursor to TES. Applicable descriptions are given of instrument design, technology challenges, implementation and operations for both.

  10. Sodium Dichromate Barrel Landfill expedited response action proposal

    SciTech Connect

    Not Available

    1993-09-01

    The US Environmental Protection Agency (EPA) and Washington State Department of Ecology (Ecology) recommended that the US Department of Energy (DOE) prepare an expedited response action (ERA) for the Sodium Dichromate Barrel Landfill. The Sodium Dichromate Barrel Disposal Site was used in 1945 for disposal of crushed barrels. The site location is the sole waste site within the 100-IU-4 Operable Unit. The Waste Information Data System (WIDS 1992) assumes that the crushed barrels contained 1% residual sodium dichromate at burial time and that only buried crushed barrels are at the site. Burial depth is shallow since visual inspection finds numerous barrel debris on the surface. A non-time-critical ERA proposal includes preparation of an engineering evaluation and cost analysis (EE/CA) section. The EE/CA is a rapid, focused evaluation of available technologies using specific screening factors to assess feasibility, appropriateness, and cost. The ERA goal is to reduce the potential for any contaminant migration from the landfill to the soil column, groundwater, and Columbia River. Since the landfill is the only waste site within the operable unit, the ERA will present a final remediation of the 100-IU-4 operable unit.

  11. Composting barrel for sustainable organic waste management in Bangladesh.

    PubMed

    Moqsud, Md Azizul; Bushra, Quazi Sifat; Rahman, M H

    2011-12-01

    To ensure quick and uniform aerobic stabilization of biowaste through domestic composting and to prevent malodorous emissions, two modifications were made to a conventional steel barrel composter by: (1) providing 0.0125 m diameter openings throughout the sides and (2) placing a 0.0254 m diameter perforated polyvinyl chloride (PVC) pipe in the middle portion of the barrel. The volume of composting waste before modification of the composting barrel was 40% of the original volume and it was 70%, 4 weeks following the modifications. In addition, the nutrients in the compost were found to be in a more suitable range after modification of the composting barrel. The carbon-nitrogen ratio (C/N) of the compost was in the ideal range of 11-15 in the modified composting reactor but it was quite high (24-25) in the conventional barrel. This modified barrel composting plant proved to be an efficient, eco-friendly, cost-effective solution for the management of organic solid waste materials in developing and technologically less sophisticated countries such as Bangladesh.

  12. MODIS technical report series. Volume 3: MODIS airborne simulator level 1B data user's guide

    NASA Technical Reports Server (NTRS)

    Gumley, Liam E.; Hubanks, Paul A.; Masuoka, Edward J.

    1994-01-01

    The purpose of this document is to describe the characteristics of moderate resolution imaging spectroradiometer (MODIS) airborne simulator level 1B data, the calibration and geolocation methods used in processing, the structure and format of the level 1B data files, and methods for accessing the data. The MODIS airborne simulator is a scanning spectrometer which flies on a NASA ER-2 and provides spectral information similar to that which will be provided by the MODIS.

  13. Compact Infrared Spectrometers

    NASA Technical Reports Server (NTRS)

    Mouroulis, Pantazis

    2009-01-01

    Concentric spectrometer forms are advantageous for constructing a variety of systems spanning the entire visible to infrared range. Spectrometer examples are given, including broadband or high resolution forms. Some issues associated with the Dyson catadioptric type are also discussed.

  14. Electronics for a Spectrometer

    NASA Image and Video Library

    2014-01-24

    NASA has provided part of the electronics package for an instrument called the Double Focusing Mass Spectrometer, which is part of the Swiss-built Rosetta Orbiter Spectrometer for Ion and Neutral Analysis ROSINA instrument.

  15. Compact Infrared Spectrometers

    NASA Technical Reports Server (NTRS)

    Mouroulis, Pantazis

    2009-01-01

    Concentric spectrometer forms are advantageous for constructing a variety of systems spanning the entire visible to infrared range. Spectrometer examples are given, including broadband or high resolution forms. Some issues associated with the Dyson catadioptric type are also discussed.

  16. Aroma potential of oak battens prepared from decommissioned oak barrels.

    PubMed

    Li, Sijing; Crump, Anna M; Grbin, Paul R; Cozzolino, Daniel; Warren, Peter; Hayasaka, Yoji; Wilkinson, Kerry L

    2015-04-08

    During barrel maturation, volatile compounds are extracted from oak wood and impart aroma and flavor to wine, enhancing its character and complexity. However, barrels contain a finite pool of extractable material, which diminishes with time. As a consequence, most barrels are decommissioned after 5 or 6 years. This study investigated whether or not decommissioned barrels can be "reclaimed" and utilized as a previously untapped source of quality oak for wine maturation. Oak battens were prepared from staves of decommissioned French and American oak barrels, and their composition analyzed before and after toasting. The oak lactone glycoconjugate content of untoasted reclaimed oak was determined by liquid chromatography-tandem mass spectrometry, while the concentrations of cis- and trans-oak lactone, guaiacol, 4-methlyguaiacol, vanillin, eugenol, furfural, and 5-methylfurfural present in toasted reclaimed oak were determined by gas chromatography-mass spectrometry. Aroma potential was then evaluated by comparing the composition of reclaimed oak with that of new oak. Comparable levels of oak lactone glycoconjugates and oak volatiles were observed, demonstrating the aroma potential of reclaimed oak and therefore its suitability as a raw material for alternative oak products, i.e., chips or battens, for the maturation of wine. The temperature profiles achieved during toasting were also measured to evaluate the viability of any yeast or bacteria present in reclaimed oak.

  17. β-Barrel membrane protein assembly by the Bam complex.

    PubMed

    Hagan, Christine L; Silhavy, Thomas J; Kahne, Daniel

    2011-01-01

    β-barrel membrane proteins perform important functions in the outer membranes (OMs) of Gram-negative bacteria and of the mitochondria and chloroplasts of eukaryotes. The protein complexes that assemble these proteins in their respective membranes have been identified and shown to contain a component that has been conserved from bacteria to humans. β-barrel proteins are handled differently from α-helical membrane proteins in the cell in order to efficiently transport them to their final locations in unfolded but folding-competent states. The mechanism by which the assembly complex then binds, folds, and inserts β-barrels into the membrane is not well understood, but recent structural, biochemical, and genetic studies have begun to elucidate elements of how the complex provides a facilitated pathway for β-barrel assembly. Ultimately, studies of the mechanism of β-barrel assembly and comparison to the better-understood process of α-helical membrane protein assembly will reveal whether there are general principles that guide the folding and insertion of all membrane proteins.

  18. Upgrade of the CMS muon trigger system in the barrel region

    NASA Astrophysics Data System (ADS)

    Rabady, Dinyar; Ero, Janos; Flouris, Giannis; Fulcher, Jonathan; Loukas, Nikitas; Paradas, Evangelos; Reis, Thomas; Sakulin, Hannes; Wulz, Claudia-Elisabeth

    2017-02-01

    To maintain the excellent performance shown during the LHC's Run-1 the Level-1 Trigger of the Compact Muon Solenoid experiment underwent a significant upgrade. One part of this upgrade is the re-organization of the muon trigger path from a subsystem-centric view in which hits in the drift tubes (DT), the cathode strip chambers (CSC), and the resistive plate chambers (RPC) were treated separately in dedicated track-finding systems to one in which complementary detector systems for a given region (barrel, overlap, and endcap) are merged at the track-finding level. This fundamental restructuring of the muon trigger system required the development of a system to receive track candidates from the track-finding layer, remove potential duplicate tracks, and forward the best candidates to the global decision layer. An overview will be given of the new track-finder system for the barrel region, the Barrel Muon Track Finder (BMTF), as well as the cancel-out and sorting layer: the upgraded Global Muon Trigger (μGMT). Both the BMTF and μGMT have been implemented in a Xilinx Virtex-7 card utilizing the microTCA architecture. While the BMTF improves on the proven and well-tested algorithms used in the Drift Tube Track Finder during Run-1, the μGMT is an almost complete re-development due to the re-organization of the underlying systems from track-finders for a specific detector to regional track finders covering a given area of the whole detector. Additionally the μGMT calculates a muon's isolation using energy information received from the calorimeter trigger. This information is added to the muon objects forwarded to the global decision layer, the so-called Global Trigger.

  19. Small arms mini-fire control system: fiber-optic barrel deflection sensor

    SciTech Connect

    Rajic, Slobodan; Datskos, Panos G

    2012-01-01

    Traditionally the methods to increase firearms accuracy, particularly at distance, have concentrated on barrel isolation (free floating) and substantial barrel wall thickening to gain rigidity. This barrel stiffening technique did not completely eliminate barrel movement but the problem was significantly reduced to allow a noticeable accuracy enhancement. This process, although highly successful, came at a very high weight penalty. Obviously the goal would be to lighten the barrel (firearm), yet achieve even greater accuracy. Thus, if lightweight barrels could ultimately be compensated for both their static and dynamic mechanical perturbations, the result would be very accurate, yet significantly lighter weight, weapons. We discuss our development of a barrel reference sensor system that is designed to accomplish this ambitious goal. Our optical fiber-based sensor monitors the barrel muzzle position and autonomously compensates for any induced perturbations. The reticle is electronically adjusted in position to compensate for the induced barrel deviation in real time.

  20. Small arms mini-fire control system: fiber-optic barrel deflection sensor

    NASA Astrophysics Data System (ADS)

    Rajic, S.; Datskos, P.; Lawrence, W.; Marlar, T.; Quinton, B.

    2012-06-01

    Traditionally the methods to increase firearms accuracy, particularly at distance, have concentrated on barrel isolation (free floating) and substantial barrel wall thickening to gain rigidity. This barrel stiffening technique did not completely eliminate barrel movement but the problem was significantly reduced to allow a noticeable accuracy enhancement. This process, although highly successful, came at a very high weight penalty. Obviously the goal would be to lighten the barrel (firearm), yet achieve even greater accuracy. Thus, if lightweight barrels could ultimately be compensated for both their static and dynamic mechanical perturbations, the result would be very accurate, yet significantly lighter weight, weapons. We discuss our development of a barrel reference sensor system that is designed to accomplish this ambitious goal. Our optical fiber-based sensor monitors the barrel muzzle position and autonomously compensates for any induced perturbations. The reticle is electronically adjusted in position to compensate for the induced barrel deviation in real time.

  1. Spherical grating spectrometers

    NASA Astrophysics Data System (ADS)

    O'Donoghue, Darragh; Clemens, J. Christopher

    2014-07-01

    We describe designs for spectrometers employing convex dispersers. The Offner spectrometer was the first such instrument; it has almost exclusively been employed on satellite platforms, and has had little impact on ground-based instruments. We have learned how to fabricate curved Volume Phase Holographic (VPH) gratings and, in contrast to the planar gratings of traditional spectrometers, describe how such devices can be used in optical/infrared spectrometers designed specifically for curved diffraction gratings. Volume Phase Holographic gratings are highly efficient compared to conventional surface relief gratings; they have become the disperser of choice in optical / NIR spectrometers. The advantage of spectrometers with curved VPH dispersers is the very small number of optical elements used (the simplest comprising a grating and a spherical mirror), as well as illumination of mirrors off axis, resulting in greater efficiency and reduction in size. We describe a "Half Offner" spectrometer, an even simpler version of the Offner spectrometer. We present an entirely novel design, the Spherical Transmission Grating Spectrometer (STGS), and discuss exemplary applications, including a design for a double-beam spectrometer without any requirement for a dichroic. This paradigm change in spectrometer design offers an alternative to all-refractive astronomical spectrometer designs, using expensive, fragile lens elements fabricated from CaF2 or even more exotic materials. The unobscured mirror layout avoids a major drawback of the previous generation of catadioptric spectrometer designs. We describe laboratory measurements of the efficiency and image quality of a curved VPH grating in a STGS design, demonstrating, simultaneously, efficiency comparable to planar VPH gratings along with good image quality. The stage is now set for construction of a prototype instrument with impressive performance.

  2. Treatment Method for Fermi Barrel Sodium Metal Residues

    SciTech Connect

    Steven R. Sherman; Collin J. Knight

    2005-06-01

    Fermi barrels are 55-gallon drums that once contained bulk sodium metal from the shutdown Fermi 1 breeder reactor facility, and now contain residual sodium metal and other sodium/air reaction products. This report provides a residual sodium treatment method and proposed quality assurance steps that will ensure that all residual sodium is deactivated and removed from the Fermi barrels before disposal. The treatment method is the application of humidified carbon dioxide to the residual sodium followed by a water wash. The experimental application of the treatment method to six Fermi barrels is discussed, and recommendations are provided for further testing and evaluation of the method. Though more testing would allow for a greater refinement of the treatment technique, enough data has been gathered from the tests already performed to prove that 100% compliance with stated waste criteria can be achieved.

  3. The impact of acceleration on barrel/launch package design

    SciTech Connect

    Ang, J.A. ); Hauze, G. )

    1991-01-01

    This paper discusses the impact of launch acceleration on the design of electromagnetic launcher barrels and on the design of associated launch packages. This is of particular interest because launch package size and mass directly affect the overall armament system size and mass. A common design approach is to use as the peak launch acceleration, the maximum acceleration which the projectile can be designed to withstand. While this approach will minimize barrel length, it may also yield an excessively large overall system size and mass, especially for the long, slender projectile configurations which are desired for high aero-thermal and terminal ballistics performance. An alternate design approach is described which balances the goals of reducing barrel length with reducing launch package mass. Results illustrate the benefits of this balanced design approach on overall armament system size and mass.

  4. A monodisperse transmembrane α-helical peptide barrel

    NASA Astrophysics Data System (ADS)

    Mahendran, Kozhinjampara R.; Niitsu, Ai; Kong, Lingbing; Thomson, Andrew R.; Sessions, Richard B.; Woolfson, Derek N.; Bayley, Hagan

    2017-05-01

    The fabrication of monodisperse transmembrane barrels formed from short synthetic peptides has not been demonstrated previously. This is in part because of the complexity of the interactions between peptides and lipids within the hydrophobic environment of a membrane. Here we report the formation of a transmembrane pore through the self-assembly of 35 amino acid α-helical peptides. The design of the peptides is based on the C-terminal D4 domain of the Escherichia coli polysaccharide transporter Wza. By using single-channel current recording, we define discrete assembly intermediates and show that the pore is most probably a helix barrel that contains eight D4 peptides arranged in parallel. We also show that the peptide pore is functional and capable of conducting ions and binding blockers. Such α-helix barrels engineered from peptides could find applications in nanopore technologies such as single-molecule sensing and nucleic-acid sequencing.

  5. Calibration and operation of the PNL Barrel Assayer

    SciTech Connect

    Arthur, R J

    1991-07-01

    Pacific Northwest Laboratory operates a Barrel Assayer to measure the radionuclide content of 208-liter waste drums. This mobile apparatus is designed to provide quantitative information on each radioisotope in a drum and to recognize and locate hot spots within the drum. A lead-collimated intrinsic-germanium detector mounted on a moveable platform vertically scans a rotating drum for gamma-ray activity while 62 stationary {sup 10}BF{sub 3} tubes measure neutrons emitted by transuranic isotopes within the waste. Several approaches have been used to document the controls under which the Barrel Assayer has been operated from February 1989 through December 1990. Resin-filled 208-1 calibration barrels containing known quantities of {sup 60}Co, {sup 137}Cs, and {sup 134}Cs were measured by the Barrel Assayer and found to be well within 25% of the known values. A thorium nitrate standard that served as the secondary, or field, standard verified that the detector has been within calibration during the period from February 1989 through December 1990. In previous testing, 23 waste drums were assayed at several commercial nuclear power plants. Subsequently, aliquots from the top, middle, and bottom of the barrels were analyzed. The ratio of grab-sample concentration to direct-assay concentration averaged {minus}1.6 for one plant and +1.3 for another. Results using the Barrel Assayer were also comparable to those obtained using Safeguards Security's Segmented Gamma-ray Scanner (SGS) system in a cross-calibration experiment performed by a third party on several drums containing TRU wastes. 6 refs., 6 figs., 9 tabs.

  6. Pressurized core barrel for sampling gas-charged marine sediments

    SciTech Connect

    Denk, E.W.; Dunlap, W.A.; Bryant, W.R.; Milberger, L.J.; Whelan, T.J. III

    1981-01-01

    This paper describes a recently developed pressurized core barrel which can sample gas-charged sediments and maintain them at the downhole pressure for subsequent testing. The pressurized samples are placed in a hyperbaric chamber manned by geotechnically trained ''divers''. Here, various tests are performed on the samples at the downhole pressure. These tests include undrained shear strength and gas content determinations. Additional tests, such as consolidation and triaxial compression, are performed by mounting samples in pressurized test devices which are then passed out of the hyperbaric chamber. The pressurized core barrel was designed to be operated in a standard geotechnical borehole. A discussion of the design features is presented.

  7. Railgun barrel and secondary armature characterization using voltage monitor arrays

    NASA Astrophysics Data System (ADS)

    Calvin, Hugh A.; Virostek, Steve P.

    1992-01-01

    Although breech and muzzle voltage monitors are common on most railgun experiments, voltage monitors located at intermediate positions along the rails usually are not present. These monitors, combined with other common measurements such as armature position and velocity, can provide a wealth of valuable information for characterizing the railgun barrel and the armature. Expressions for calculating the barrel inductance gradient, and the resistance gradient, are developed. When the plasma armature develops a secondary arc, the voltage monitor array can provide information about the secondary arc voltage, current, and rate of change of current.

  8. Cross-Barrel Temperature Difference Due to Wall Thickness Variation

    DTIC Science & Technology

    1993-03-01

    atmosphere. F Is the radiation interchange factor between the barrel outer wall and the environment (in our case, we assume F = 0.95), and a is the Stefan ...barrel metal [kg/mrJ o Stefan -Boltzmann constant = 5.669 x 10-8 J/(m2 s K4) * azimuthal coordinate In transverse plane azimuthal coordinate in...Pomey SMCAR-CCB-DS, P. Votlis Fort Knox, KY 40121-5212 SMCAR-CCB-DS, C. Andrade SMCAR-LBD-D, J. Zweig 1 Paul Gough Associates, Inc. SMCAR-CCB, L

  9. English as a Second Language. Level 1.

    ERIC Educational Resources Information Center

    Lewandowski, Carol

    This guide is intended for use in a level 1 course in English as a second language that was developed as a component of a workplace literacy program for persons employed in the manufacturing and service industries. The course is structured so that, upon its completion, students will be able to accomplish the following: ask grammatically correct…

  10. Centrifugal Barrel Finishing Of Turbine-Blade "Fir Trees"

    NASA Technical Reports Server (NTRS)

    Mandel, Johnny L.

    1990-01-01

    Modified centrifugal barrel-finishing machine imparts desired residual compressive stresses to "fir trees" of turbine blades. Centrifugal forces generate compressive stresses, which are transmitted to turbine blades through abrasive slurries in which suspended. Eliminates need for shot peening, rounding of edges and burrs caused by shot peening and, consequently, need for mass finishing operations to remove burrs. Improves surface finish of "fir trees".

  11. Centrifugal Barrel Finishing Of Turbine-Blade "Fir Trees"

    NASA Technical Reports Server (NTRS)

    Mandel, Johnny L.

    1990-01-01

    Modified centrifugal barrel-finishing machine imparts desired residual compressive stresses to "fir trees" of turbine blades. Centrifugal forces generate compressive stresses, which are transmitted to turbine blades through abrasive slurries in which suspended. Eliminates need for shot peening, rounding of edges and burrs caused by shot peening and, consequently, need for mass finishing operations to remove burrs. Improves surface finish of "fir trees".

  12. Modulation of artificial whisking related signals in barrel cortex

    PubMed Central

    Bezdudnaya, Tatiana

    2014-01-01

    Rats use rhythmic whisker movements, called active whisking, to sense the environment, which include whisker protractions followed by retractions at various frequencies. Using a proxy of active whisking in anesthetized rats, called artificial whisking, which is induced by electrically stimulating the facial motor nerve, we characterized the neural responses evoked in the barrel cortex by whisking in air (without contact) and on a surface (with contact). Neural responses were compared between distinct network states consisting of cortical deactivation (synchronized slow oscillations) and activation (desynchronized state) produced by neuromodulation (cholinergic or noradrenergic stimulation in neocortex or thalamus). Here we show that population responses in the barrel cortex consist of a robust signal driven by the onset of the whisker protraction followed by a whisking retraction signal that emerges during low frequency whisking on a surface. The whisking movement onset signal is suppressed by increasing whisking frequency, is controlled by cortical synaptic inhibition, is suppressed during cortical activation states, is little affected by whisking on a surface, and is ubiquitous in ventroposterior medial (VPM) thalamus, barrel cortex, and superior colliculus. The whisking retraction signal codes the duration of the preceding whisker protraction, is present in thalamocortical networks but not in superior colliculus, and is robust during cortical activation; a state associated with natural exploratory whisking. The expression of different whisking signals in forebrain and midbrain may define the sensory processing abilities of those sensorimotor circuits. Whisking related signals in the barrel cortex are controlled by network states that are set by neuromodulators. PMID:25505118

  13. 27 CFR 25.144 - Rebranding barrels and kegs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Marks, Brands, and Labels § 25.144 Rebranding barrels and... permanently remove or durably cover the original marks and brands after notifying the appropriate TTB officer... the original marks and brands if the brewer: (1) Adopts a trade name substantially identical to the...

  14. New results in meson spectroscopy from the crystal barrel experiment

    SciTech Connect

    Meyer, C.A.

    1994-04-01

    Recent observations by the Crystal Barrel experiment of two scalar resonances, f{sub o}(1365) and a{sub o}(1450) have allowed the authors to clarify the members of the scalar nonet. In addition, a third scalar, f{sub o}(1500), appears to be supernumerary, and is a candidate for the scalar glueball expected near 1500 MeV.

  15. 9. Generator Barrel and Rotor of Unit 1, view to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Generator Barrel and Rotor of Unit 1, view to the southeast, showing part of the rotor and generator coils along top of photograph and southeast entry stairwell and doors in lower center of photograph. - Washington Water Power Clark Fork River Noxon Rapids Hydroelectric Development, Powerhouse, South bank of Clark Fork River at Noxon Rapids, Noxon, Sanders County, MT

  16. 14. Interior view, grain tanks (bins). Barrel view of tunnel ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Interior view, grain tanks (bins). Barrel view of tunnel for load-out belt conveyor system located below tanks. Square, numbered spouts gravity-feed grain from overhead bins onto belt. - Saint Anthony Elevator No. 3, 620 Malcom Avenue, Southeast, Minneapolis, Hennepin County, MN

  17. 4. AERIAL 'BARREL' SHOT OF THE PATH TRANSIT SYSTEM BRIDGE, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. AERIAL 'BARREL' SHOT OF THE PATH TRANSIT SYSTEM BRIDGE, LOOKING SOUTHEAST TOWARDS JERSEY CITY. TO THE RIGHT ARE THE NEWARK TURNPIKE AND THE CONRAIL BRIDGE (HAER No. NJ-43). THE PULASKI SKYWAY (HAER No. NJ-34) IS IN THE BACKGROUND TO THE RIGHT - Path Transit System Bridge, Spanning Hackensack River, Kearny, Hudson County, NJ

  18. Postsynaptic Deregulation in GAP-43 Heterozygous Mouse Barrel Cortex

    PubMed Central

    Kelly, Emily A.; Tremblay, Marie-Ève; McCasland, James S.

    2010-01-01

    Formation of whisker-related barrels in primary somatosensory cortex (S1) requires communication between presynaptic thalamocortical afferents (TCAs) and postsynaptic cortical neurons. GAP-43 is crucially involved in targeting TCAs to postsynaptic S1 neurons but its influence on the interactions between these 2 elements has not been explored. Here, we tested the hypothesis that reduced early expression of presynaptic GAP-43 (GAP-43 heterozygous [HZ] mice) alters postsynaptic differentiation of barrel cells. We found a transient increase in cytochrome oxidase staining between P6 and P14 in HZ animals, indicative of increased metabolic activity in barrel cortex during this time. Golgi impregnation and microtubule-associated protein 2 immunohistochemistry showed anomalous dendritic patterning in GAP-43 HZ cortex at P5, with altered dendritic length and branching and abnormal retention of dendrites that extend into developing septa. This deficiency was no longer apparent at P7, suggesting partial recovery of dendritic pruning processes. Finally, we showed early defects in synaptogenesis from P4 to P5 with increased colocalization of NR1 and GluR1 staining in HZ mice. By P7, this colocalization had normalized to wild type levels. Taken together, our findings suggest abnormal postsynaptic differentiation in GAP-43 HZ cortex during early barrel development, followed by adaptive compensation and partial phenotypic rescue. PMID:19915093

  19. 13. Interior view, grain tanks (bins). Barrel view of overhead ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Interior view, grain tanks (bins). Barrel view of overhead (fill) conveyor gallery bridge extending through tops of tanks just below roofs. Grain tripper straddles belt conveyor at mid-view. - Saint Anthony Elevator No. 3, 620 Malcom Avenue, Southeast, Minneapolis, Hennepin County, MN

  20. 1. INTERIOR VIEW WITH NAVE, BARREL VAULTED SOLEA, ICONOSTAS WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. INTERIOR VIEW WITH NAVE, BARREL VAULTED SOLEA, ICONOSTAS WITH ICON AND SANCTUARY. IN ARCH ABOVE THE SANCTUARY IS THE TABLE OF ABRAHAM. THE ICONOSTAS INCLUDES ICONS OF THE ARCHANGEL MICHAEL, THE HOLY TRINITY, MOTHER OF GOD HOLDING THE CHRIST CHILD, JESUS. - Holy Trinity-Holy Cross Greek Orthodox Church, 200 Nineteenth Street South, Birmingham, Jefferson County, AL

  1. 8. Generator Barrel and Shaft of Unit 1, view to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Generator Barrel and Shaft of Unit 1, view to the northwest, with turbine shaft and thrust bearing visible in upper center of photograph. - Washington Water Power Clark Fork River Noxon Rapids Hydroelectric Development, Powerhouse, South bank of Clark Fork River at Noxon Rapids, Noxon, Sanders County, MT

  2. [Death after explosion of an "empty" acetone barrel].

    PubMed

    Preuss-Wössner, Johanna; Gerling, Ivana

    2013-01-01

    Inappropriate disposal of (hazardous) waste material led to an explosion of an acetone-air mixture in a metal barrel. The lid was blown off and caused blunt traumatization with fatal exsanguination. The case furnishes information relevant for the practical teaching of forensic knowledge and the indicated consultation of medico-legal experts already at scene.

  3. VIEW, LOOKING SOUTHWEST OF GOLD AMALGAMATION ROOM, SHOWING AMALGAMATION BARREL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW, LOOKING SOUTHWEST OF GOLD AMALGAMATION ROOM, SHOWING AMALGAMATION BARREL AT CENTER FOREGROUND, BULLION FURNACE IN LARGE HOOD BEHIND IT, AND GOLD RETORT IN BACKGROUND HOOD. NOTE OVERHEAD MONORAIL FOR MATERIALS HANDLING. - Shenandoah-Dives Mill, 135 County Road 2, Silverton, San Juan County, CO

  4. Barrelettes without barrels in the American water shrew.

    PubMed

    Catania, Kenneth C; Catania, Elizabeth H; Sawyer, Eva K; Leitch, Duncan B

    2013-01-01

    Water shrews (Sorex palustris) depend heavily on their elaborate whiskers to navigate their environment and locate prey. They have small eyes and ears with correspondingly small optic and auditory nerves. Previous investigations have shown that water shrew neocortex is dominated by large representations of the whiskers in primary and secondary somatosensory cortex (S1 and S2). Flattened sections of juvenile cortex processed for cytochrome oxidase revealed clear borders of the whisker pad representation in S1, but no cortical barrels. We were therefore surprised to discover prominent barrelettes in brainstem of juvenile water shrews in the present investigation. These distinctive modules were found in the principal trigeminal nucleus (PrV), and in two of the three spinal trigeminal subnuclei (interpolaris--SpVi and caudalis--SpVc). Analysis of the shrew's whisker pad revealed the likely relationship between whiskers and barrelettes. Barrelettes persisted in adult water shrew PrV, but barrels were also absent from adult cortex. Thus in contrast to mice and rats, which have obvious barrels in primary somatosensory cortex and less clear barrelettes in the principal nucleus, water shrews have clear barrelettes in the brainstem and no barrels in the neocortex. These results highlight the diverse ways that similar mechanoreceptors can be represented in the central nervous systems of different species.

  5. A summary of the BARREL campaigns: Technique for studying electron precipitation.

    PubMed

    Woodger, L A; Halford, A J; Millan, R M; McCarthy, M P; Smith, D M; Bowers, G S; Sample, J G; Anderson, B R; Liang, X

    2015-06-01

    BARREL observed electron precipitation over wide range of energy and timescalesPrecipitating electron distribution is determined using spectroscopy for 19 January 2013 eventBARREL timing data has accuracy within sampling interval of 0.05 s.

  6. [LEVEL 1--a new blood warming device].

    PubMed

    Arndt, M; Hofmockel, R; Benad, G

    1994-01-01

    Hypothermia of less than 35 degrees C, which frequently occurs in connection with massive blood transfusion, is a serious problem in many patients, in particular in those with polytrauma. The restoration of normal body temperature is very important and requires the use of a rapidly-acting, efficient and safe blood warmer, which is able to work effectively at high flow-rates. The LEVEL 1 (Technologies, Rockland, MA) is such a new blood warmer and works as a heat-exchanger via an aluminium column. This system is highly effective. Six hundred ml of sodium chloride 0.9% are warmed from 4 to 35 degrees C within one minute. This device is quickly operational and has a low priming volume. The LEVEL 1 is the only device currently available which is able to warm blood sufficiently during a very rapid blood transfusion.

  7. Level 1 Daq System for Kloe

    NASA Astrophysics Data System (ADS)

    Aloisio, A.; Cavaliere, S.; Cevenini, F.; Della Volpe, D.; Merola, L.; Anastasio, A.; Fiore, D. J.

    KLOE is a general purpose detector optimized to observe CP violation in K0 decays. This detector will be installed at the DAΦNE Φ-factory, in Frascati (Italy) and it is expected to run at the end of 1997. The KLOE DAQ system can be divided mainly into the front-end fast readout section (the Level 1 DAQ), the FDDI Switch and the processor farm. The total bandwidth requirement is estimated to be of the order of 50 Mbyte/s. In this paper, we describe the Level 1 DAQ section, which is based on custom protocols and hardware controllers, developed to achieve high data transfer rates and event building capabilities without software overhead.

  8. 15 CFR 241.6 - Classes of barrels for tolerance application.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE STANDARDS FOR BARRELS BARRELS FOR... other dry commodities other than cranberries, are hereby divided into two classes as follows: (a) Class... (b) Class 2 shall include all barrels at least one dimension of which is in error by more than the...

  9. ESA Swarm Mission - Level 1b Products

    NASA Astrophysics Data System (ADS)

    Tøffner-Clausen, Lars; Floberghagen, Rune; Mecozzi, Riccardo; Menard, Yvon

    2014-05-01

    Swarm, a three-satellite constellation to study the dynamics of the Earth's magnetic field and its interactions with the Earth system, has been launched in November 2013. The objective of the Swarm mission is to provide the best ever survey of the geomagnetic field and its temporal evolution, which will bring new insights into the Earth system by improving our understanding of the Earth's interior and environment. The Level 1b Products of the Swarm mission contain time-series of the quality screened, calibrated, corrected, and fully geo-localized measurements of the magnetic field intensity, the magnetic field vector (provided in both instrument and Earth-fixed frames), the plasma density, temperature, and velocity. Additionally, quality screened and pre-calibrated measurements of the nongravitational accelerations are provided. Geo-localization is performed by 24- channel GPS receivers and by means of unique, three head Advanced Stellar Compasses for high-precision satellite attitude information. The Swarm Level 1b data will be provided in daily products separately for each of the three Swarm spacecrafts. This poster will present detailed lists of the contents of the Swarm Level 1b Products and brief descriptions of the processing algorithms used in the generation of these data.

  10. ESA Swarm Mission - Level 1b Products

    NASA Astrophysics Data System (ADS)

    Tøffner-Clausen, L.; Floberghagen, R.; Mecozzi, R.; Menard, Y.; Swarm Level 1b Algorithms Team

    2011-12-01

    The ESA Earth Explorer mission, Swarm, is scheduled for launch in July 2012. The objective of the Swarm mission is to provide the best ever survey of the geomagnetic field and its temporal evolution by means of three formation flying spacecrafts in near Earth, polar orbits between 300 and 530 km altitude. The Level 1b Products of the Swarm mission contain time-series of the quality screened, calibrated, corrected, and fully geo-localized measurements of the magnetic field intensity, the magnetic field vector (provided in both instrument and Earth-fixed frames), the plasma density, temperature, and velocity. Additionally, quality screened and pre-calibrated measurements of the non-gravitational accelerations are provided. Geo-localization is performed by 24-channel GPS receivers and by means of unique, three head Advanced Stellar Compasses for high-precision satellite attitude information. The Swarm Level 1b data will be provided in daily products separately for each of the three Swarm spacecrafts. This poster will present detailed lists of the contents of the Swarm Level 1b Products and brief descriptions of the processing algorithms used in the generation of these data.

  11. PLANCK LFI Level 1 Processing During Operations

    NASA Astrophysics Data System (ADS)

    Morisset, N.; Rohlfs, R.; Türler, M.; Meharga, M.; Binko, P.; Beck, M.; Frailis, M.; Zacchei, A.; Galeotta, S.

    2008-08-01

    The PLANCK satellite with two on-board instruments, a Low Frequency Instrument (LFI) and a High Frequency Instrument (HFI) is foreseen to be launched in August 2008 with Ariane 5. The Data Processing Centre (DPC) in Trieste, Italy for LFI is responsible for processing the PLANCK LFI data. The ISDC data centre in Switzerland is responsible for developing/installing and maintaining the software for the LFI Level 1 data processing presented here. The main tasks of the Level 1 processing are to retrieve the daily available consolidated scientific and housekeeping (HK) data of the LFI instrument from the Mission Operation Centre in Darmstadt (MOC); to sort them by time and by type (detector, observing mode, etc...); to extract the spacecraft attitude information from auxiliary files; to flag the data according to several criteria; and to archive the resulting Time Ordered Information (TOI). The TOI data generated by the level 1 pipeline are the input for the more scientific LFI level 2 processing. The TOI are first stored in FITS format and then ingested into the Data Management Component (DMC) system, which is the interface to the LFI DPC database. In addition, the ISDC also developed software tools to display and perform a quick look analysis of the data.

  12. EOS MLS Level 1B Data Processing Software. Version 3

    NASA Technical Reports Server (NTRS)

    Perun, Vincent S.; Jarnot, Robert F.; Wagner, Paul A.; Cofield, Richard E., IV; Nguyen, Honghanh T.; Vuu, Christina

    2011-01-01

    This software is an improvement on Version 2, which was described in EOS MLS Level 1B Data Processing, Version 2.2, NASA Tech Briefs, Vol. 33, No. 5 (May 2009), p. 34. It accepts the EOS MLS Level 0 science/engineering data, and the EOS Aura spacecraft ephemeris/attitude data, and produces calibrated instrument radiances and associated engineering and diagnostic data. This version makes the code more robust, improves calibration, provides more diagnostics outputs, defines the Galactic core more finely, and fixes the equator crossing. The Level 1 processing software manages several different tasks. It qualifies each data quantity using instrument configuration and checksum data, as well as data transmission quality flags. Statistical tests are applied for data quality and reasonableness. The instrument engineering data (e.g., voltages, currents, temperatures, and encoder angles) is calibrated by the software, and the filter channel space reference measurements are interpolated onto the times of each limb measurement with the interpolates being differenced from the measurements. Filter channel calibration target measurements are interpolated onto the times of each limb measurement, and are used to compute radiometric gain. The total signal power is determined and analyzed by each digital autocorrelator spectrometer (DACS) during each data integration. The software converts each DACS data integration from an autocorrelation measurement in the time domain into a spectral measurement in the frequency domain, and estimates separately the spectrally, smoothly varying and spectrally averaged components of the limb port signal arising from antenna emission and scattering effects. Limb radiances are also calibrated.

  13. The imaging spectrometer approach

    NASA Technical Reports Server (NTRS)

    Wellman, J. B.

    1982-01-01

    Two important sensor design drivers are the requirement for spatial registration of the spectral components and the implementation of the advanced multispectral capability, including spectral band width, number of bands and programmability. The dispersive approach, fundamental to the imaging spectrometer concept, achieves these capabilities by utilizing a spectrometer to disperse the spectral content while preserving the spatial identity of the information in the cross-track direction. Area array detectors in the spectrometer focal plane detect and store the spatial and multispectral content for each line of the image. The choice of spectral bands, image IFOV and swath width is implemented by programmed readout of the focal plane. These choices in conjunction with data compression are used to match the output data rate with the telemetry link capability. Progress in the key technologies of optics, focal plane detector arrays, onboard processing, and focal plane cooling supports the viability of the imaging spectrometer approach.

  14. Composite Spectrometer Prisms

    NASA Technical Reports Server (NTRS)

    Breckinridge, J. B.; Page, N. A.; Rodgers, J. M.

    1985-01-01

    Efficient linear dispersive element for spectrometer instruments achieved using several different glasses in multiple-element prism. Good results obtained in both two-and three-element prisms using variety of different glass materials.

  15. AUTOMATIC MASS SPECTROMETER

    DOEpatents

    Hanson, M.L.; Tabor, C.D. Jr.

    1961-12-01

    A mass spectrometer for analyzing the components of a gas is designed which is capable of continuous automatic operation such as analysis of samples of process gas from a continuous production system where the gas content may be changing. (AEC)

  16. A Simple Raman Spectrometer.

    ERIC Educational Resources Information Center

    Blond, J. P.; Boggett, D. M.

    1980-01-01

    Discusses some basic physical ideas about light scattering and describes a simple Raman spectrometer, a single prism monochromator and a multiplier detector. This discussion is intended for British undergraduate physics students. (HM)

  17. Fourier Transform Spectrometer System

    NASA Technical Reports Server (NTRS)

    Campbell, Joel F. (Inventor)

    2014-01-01

    A Fourier transform spectrometer (FTS) data acquisition system includes an FTS spectrometer that receives a spectral signal and a laser signal. The system further includes a wideband detector, which is in communication with the FTS spectrometer and receives the spectral signal and laser signal from the FTS spectrometer. The wideband detector produces a composite signal comprising the laser signal and the spectral signal. The system further comprises a converter in communication with the wideband detector to receive and digitize the composite signal. The system further includes a signal processing unit that receives the composite signal from the converter. The signal processing unit further filters the laser signal and the spectral signal from the composite signal and demodulates the laser signal, to produce velocity corrected spectral data.

  18. A Simple Raman Spectrometer.

    ERIC Educational Resources Information Center

    Blond, J. P.; Boggett, D. M.

    1980-01-01

    Discusses some basic physical ideas about light scattering and describes a simple Raman spectrometer, a single prism monochromator and a multiplier detector. This discussion is intended for British undergraduate physics students. (HM)

  19. Membrane potential correlates of sensory perception in mouse barrel cortex.

    PubMed

    Sachidhanandam, Shankar; Sreenivasan, Varun; Kyriakatos, Alexandros; Kremer, Yves; Petersen, Carl C H

    2013-11-01

    Neocortical activity can evoke sensory percepts, but the cellular mechanisms remain poorly understood. We trained mice to detect single brief whisker stimuli and report perceived stimuli by licking to obtain a reward. Pharmacological inactivation and optogenetic stimulation demonstrated a causal role for the primary somatosensory barrel cortex. Whole-cell recordings from barrel cortex neurons revealed membrane potential correlates of sensory perception. Sensory responses depended strongly on prestimulus cortical state, but both slow-wave and desynchronized cortical states were compatible with task performance. Whisker deflection evoked an early (<50 ms) reliable sensory response that was encoded through cell-specific reversal potentials. A secondary late (50-400 ms) depolarization was enhanced on hit trials compared to misses. Optogenetic inactivation revealed a causal role for late excitation. Our data reveal dynamic processing in the sensory cortex during task performance, with an early sensory response reliably encoding the stimulus and later secondary activity contributing to driving the subjective percept.

  20. Simulation and reconstruction of the PANDA Barrel DIRC

    NASA Astrophysics Data System (ADS)

    Dzhygadlo, R.; Gerhardt, A.; Go¨tzen, K.; Hohler, R.; Kalicy, G.; Kumawat, H.; Lehmann, D.; Lewandowski, B.; Patsyuk, M.; Peters, K.; Schepers, G.; Schmitt, L.; Schwarz, C.; Schwiening, J.; Traxler, M.; Zühlsdorf, M.; Dodokhov, V. Kh.; Britting, A.; Eyrich, W.; Lehmann, A.; Uhlig, F.; Düren, M.; Fo¨hl, K.; Hayrapetyan, A.; Kro¨ck, B.; Merle, O.; Rieke, J.; Cowie, E.; Keri, T.; Montgomery, R.; Rosner, G.; Achenbach, P.; Cardinali, M.; Hoek, M.; Lauth, W.; Sfienti, C.; Thiel, M.; Bühler, P.; Gruber, L.; Marton, J.; Suzuki, K.

    2014-12-01

    Hadronic particle identification (PID) in the barrel region of the PANDA experiment at the new Facility for Antiproton and Ion Research in Europe (FAIR) at GSI, Darmstadt will be provided by a DIRC (Detection of Internally Reflected Cherenkov light) counter. To optimize the performance and reduce the detector cost, detailed simulations of different design elements, such as the width of the radiators, the shape of the expansion volume, and the type of focusing system, were performed using Geant. Custom reconstruction algorithms were developed to match the detector geometry. We will discuss the single photon resolution and photon yield as well as the PID performance for the Barrel DIRC baseline design and several detector design options.

  1. Barrel cortex membrane potential dynamics in social touch.

    PubMed

    Lenschow, Constanze; Brecht, Michael

    2015-02-18

    The impact of social stimuli on the membrane potential dynamics of barrel cortex neurons is unknown. We obtained in vivo whole-cell recordings in the barrel cortex of head-restrained rats while they interacted with conspecifics. Social touch was associated with a depolarization and large membrane potential fluctuations locked to the rat's whisking. Both depolarization and membrane potential fluctuations were already observed prior to contact and did not occur during free whisking. This anticipatory pre-contact depolarization was not seen in passive social touch in anesthetized animals. The membrane potential fluctuations locked to the rat's whisking observed in interactions with awake conspecifics were larger than those seen for whisking onto nonconspecific stimuli (stuffed rats, objects, and the experimenter's hand). Responses did not correlate with whisker movement parameters. We conclude that responses to social touch differ from conventional tactile responses in (1) amplitude, (2) locking to whisking, and (3) pre-contact membrane potential changes.

  2. Lightweight optical barrel assembly structures for large deployable space telescopes

    NASA Astrophysics Data System (ADS)

    Warren, Peter A.; Silver, Mark J.; Dobson, Benjamin J.

    2009-08-01

    Future space based telescopes will need apertures and focal lengths that exceed the dimensions of the launch vehicle shroud. In addition to deploying the primary mirror and secondary mirror support structure, these large telescopes must also deploy the stray light and thermal barriers needed to ensure proper telescope performance. The authors present a deployable light and thermal optical barrel assembly approach for a very large telescope with a variable sun angle and fast slew rate. The Strain Energy Deployable Optical Barrel Assembly (SEDOBA) uses elastic composite hinges to power the deployment of a hierarchical truss structure that supports the thermal and stray light shroud material that form the overall system. The paper describes the overall design approach, the key component technologies, and the design and preliminary testing of a self deploying scale model prototype.

  3. Triple-barrel aorta: dissection of a healed aortic dissection.

    PubMed

    Lie, J T

    1982-08-01

    An unusual case of a triple-barrel aorta in a 51-year-old woman is described. The patient first had a spontaneous type I dissection of the aorta and acute aortic insufficiency, for which she underwent aortic valve replacement and Dacron graft replacement of the ascending aorta. She remained asymptomatic for five years with a healed aortic dissection (double-barrel aorta) distal to the graft. She then underwent a second operation for repair and poppet replacement of the malfunctioned prosthesis. Postoperative cardiac failure necessitated the use of a counterpulsation intra-aortic balloon catheter, which entered and dissected the wall of the false lumen, thus creating a triple-lumen aorta.

  4. NASA Marshall Space Flight Center Barrel-Shaped Asymmetrical Capacitor

    NASA Technical Reports Server (NTRS)

    Campbell, J. W.; Carruth, M. R.; Edwards, D. L.; Finchum, A.; Maxwell, G.; Nabors, S.; Smalley, L.; Huston, D.; Ila, D.; Zimmerman, R.

    2004-01-01

    The NASA Barrel-Shaped Asymmetrical Capacitor (NACAP) has been extensively tested at NASA Marshall Space Flight Center and the National Space Science and Technology Center. Trichel pulse emission was first discovered here. The NACAP is a magnetohydrodynamic device for electric propulsion. In air it requires no onboard propellant nor any moving parts. No performance was observed in hard vacuum. The next step shall be optimizing the technology for future applications.

  5. [Easily closed gun-barrel enterostomy. A new technique].

    PubMed

    Belliard, R; Saric, J; Dost, C; Vergne, P; Perissat, J

    1982-05-15

    The availability of continuous low rate enteral and parenteral feeding has enlarged the indications of enterostomy, notably in patients with multiple operations. However, closing an enterostomy, which may be high up in the small bowel, rises technical problems and is not always without risk. In this study a new technique of gun-barrel enterostomy easily closed with automatic sutures and without reopening of the abdominal wall is presented.

  6. Rotary combustor barrel with water-cooled baffles

    SciTech Connect

    Jurusz, M.T.

    1988-04-05

    A combustion barrel in a rotary combustor used for burning solid material is described. The rotary combustor is connected to heat exchanging equipment. The combustion barrel comprises: a generally cylindrical side wall rotatable about a central axis of rotation and having an input end and an exit end, baffle pipes, attached to the interior of the generally cylindrical side wall, extending longitudinally with adjacent baffle pipes separated by a second spacing distance more than twice as large as the first spacing distance, and having first and second pipe ends at the exit and input ends, respectively of the side wall, for agitating the solid material as the combustion barrel is rotated; a ring header, having a generally annular shape, coupled to the heat exchanging equipment, for supplying coolant to, and discharging coolant from, the cooling pipes and the baffle pipes; coupling means for coupling and sealing the first pipe ends of the cooling and baffle pipes to the ring header, supplying coolant to a first set of pipes selected from among the cooling pipes and the baffle pipes and discharging coolant from a second set of pipes corresponding to the remaining ones of the the cooling pipes and the baffle pipes; and return means for returning the coolant from the second ends of the cooling and baffle pipes in the first set of pipes to the ring header via the second set of pipes.

  7. Intrinsic mechanisms for adaptive gain rescaling in barrel cortex.

    PubMed

    Díaz-Quesada, Marta; Maravall, Miguel

    2008-01-16

    Barrel cortex neuronal responses adapt to changes in the statistics of complex whisker stimuli. This form of adaptation involves an adjustment in the input-output tuning functions of the neurons, such that their gain rescales depending on the range of the current stimulus distribution. Similar phenomena have been observed in other sensory systems, suggesting that adaptive adjustment of responses to ongoing stimulus statistics is an important principle of sensory function. In other systems, adaptation and gain rescaling can depend on intrinsic properties; however, in barrel cortex, whether intrinsic mechanisms can contribute to adaptation to stimulus statistics is unknown. To examine this, we performed whole-cell patch-clamp recordings of pyramidal cells in acute slices while injecting stochastic current stimuli. We induced changes in statistical context by switching across stimulus distributions. The firing rates of neurons adapted in response to changes in stimulus statistics. Adaptation depended on the form of the changes in stimulus distribution: in vivo-like adaptation occurred only for rectified stimuli that maintained neurons in a persistent state of net depolarization. Under these conditions, neurons rescaled the gain of their input-output functions according to the scale of the stimulus distribution, as observed in vivo. This stimulus-specific adaptation was caused by intrinsic properties and correlated strongly with the amplitude of calcium-dependent slow afterhyperpolarizations. Our results suggest that widely expressed intrinsic mechanisms participate in barrel cortex adaptation but that their recruitment is highly stimulus specific.

  8. Development and Critical Period Plasticity of the Barrel Cortex

    PubMed Central

    Erzurumlu, Reha S.; Gaspar, Patricia

    2012-01-01

    In primary sensory neocortical areas of the mammals, the distribution of sensory receptors is mapped with topographic precision and amplification in proportion to the peripheral receptor density. The visual, somatosensory and auditory cortical maps are established during a critical period in development. Throughout this window in time, the developing cortical maps are vulnerable to deleterious effects of sense organ damage or sensory deprivation. The rodent barrel cortex offers an invaluable model system to investigate mechanisms underlying the formation of topographic maps and their plasticity during development. Five rows of mystacial vibrissa (whisker) follicles on the snout and an array of sinus hairs are represented by layer IV neural modules (“barrels”) and thalamocortical axon terminals in the primary somatosensory cortex. Perinatal damage to the whiskers or the sensory nerve innervating them irreversibly alters the structural organization of the barrels. Earlier studies emphasized the role of sensory periphery in dictating whisker-specific brain maps and patterns. Recent advances in molecular genetics and analyses of genetically altered mice allow new insights into neural pattern formation in the neocortex and the mechanisms underlying critical period plasticity. Here we review the development and patterning of the barrel cortex and the critical period plasticity. PMID:22607000

  9. The representation of social facial touch in rat barrel cortex.

    PubMed

    Bobrov, Evgeny; Wolfe, Jason; Rao, Rajnish P; Brecht, Michael

    2014-01-06

    Controlled presentation of stimuli to anesthetized [1] or awake [2] animals suggested that neurons in sensory cortices respond to elementary features [3, 4], but we know little about neuronal responses evoked by social interactions. Here we investigate processing in the barrel cortex of rats engaging in social facial touch [5, 6]. Sensory stimulation by conspecifics differs from classic whisker stimuli such as deflections, contact poles [7, 8], or textures [9, 10]. A large fraction of barrel cortex neurons responded to facial touch. Social touch responses peaked when animals aligned their faces and contacted each other by multiple whiskers with small, irregular whisker movements. Object touch was associated with larger, more regular whisker movements, and object responses were weaker than social responses. Whisker trimming abolished responses. During social touch, neurons in males increased their firing on average by 44%, while neurons in females increased their firing by only 19%. In females, socially evoked and ongoing firing rates were more than 1.5-fold higher in nonestrus than in estrus. Barrel cortex represented socially different contacts by distinct firing rates, and the variation of activity with sex and sexual status could contribute to the generation of gender-specific neural constructs of conspecifics.

  10. Rapid, learning-induced inhibitory synaptogenesis in murine barrel field

    PubMed Central

    Jasinska, M.; Siucinska, E.; Cybulska-Klosowicz, A.; Pyza, E.; Furness, D.N.; Kossut, M.; Glazewski, S.

    2010-01-01

    The structure of neurones changes during development and in response to injury or alteration in sensory experience. Changes occur in the number, shape and dimensions of dendritic spines together with their synapses. However, precise data on these changes in response to learning are sparse. Here, we show using quantitative transmission electron microscopy that a simple form of learning involving mystacial vibrissae results in about 70% increase in the density of inhibitory synapses on spines of neurones located in layer IV barrels that represent the stimulated vibrissae. The spines contain one asymmetrical (excitatory) and one symmetrical (inhibitory) synapse (double-synapse spines) and their density increases 3-fold due to learning with no apparent change in the density of asymmetrical synapses. This effect seems to be specific for learning as pseudoconditioning (where the conditioned and unconditioned stimuli are delivered at random) does not lead to the enhancement of symmetrical synapses, but instead results in an up-regulation of asymmetrical synapses on spines. Symmetrical synapses of cells located in barrels receiving the conditioned stimulus show also a greater concentration of γ-amino-butyric acid (GABA) in their presynaptic terminals. These results indicate that the immediate effect of classical conditioning in the ‘conditioned’ barrels is rapid, pronounced and inhibitory. PMID:20089926

  11. Neural coding in barrel cortex during whisker-guided locomotion

    PubMed Central

    Sofroniew, Nicholas James; Vlasov, Yurii A; Hires, Samuel Andrew; Freeman, Jeremy; Svoboda, Karel

    2015-01-01

    Animals seek out relevant information by moving through a dynamic world, but sensory systems are usually studied under highly constrained and passive conditions that may not probe important dimensions of the neural code. Here, we explored neural coding in the barrel cortex of head-fixed mice that tracked walls with their whiskers in tactile virtual reality. Optogenetic manipulations revealed that barrel cortex plays a role in wall-tracking. Closed-loop optogenetic control of layer 4 neurons can substitute for whisker-object contact to guide behavior resembling wall tracking. We measured neural activity using two-photon calcium imaging and extracellular recordings. Neurons were tuned to the distance between the animal snout and the contralateral wall, with monotonic, unimodal, and multimodal tuning curves. This rich representation of object location in the barrel cortex could not be predicted based on simple stimulus-response relationships involving individual whiskers and likely emerges within cortical circuits. DOI: http://dx.doi.org/10.7554/eLife.12559.001 PMID:26701910

  12. Cellular organization of cortical barrel columns is whisker-specific.

    PubMed

    Meyer, Hanno S; Egger, Robert; Guest, Jason M; Foerster, Rita; Reissl, Stefan; Oberlaender, Marcel

    2013-11-19

    The cellular organization of the cortex is of fundamental importance for elucidating the structural principles that underlie its functions. It has been suggested that reconstructing the structure and synaptic wiring of the elementary functional building block of mammalian cortices, the cortical column, might suffice to reverse engineer and simulate the functions of entire cortices. In the vibrissal area of rodent somatosensory cortex, whisker-related "barrel" columns have been referred to as potential cytoarchitectonic equivalents of functional cortical columns. Here, we investigated the structural stereotypy of cortical barrel columns by measuring the 3D neuronal composition of the entire vibrissal area in rat somatosensory cortex and thalamus. We found that the number of neurons per cortical barrel column and thalamic "barreloid" varied substantially within individual animals, increasing by ∼2.5-fold from dorsal to ventral whiskers. As a result, the ratio between whisker-specific thalamic and cortical neurons was remarkably constant. Thus, we hypothesize that the cellular architecture of sensory cortices reflects the degree of similarity in sensory input and not columnar and/or cortical uniformity principles.

  13. Spectrometer technology recommendations

    NASA Astrophysics Data System (ADS)

    Wilson, William J.

    1988-08-01

    A typical heterodyne remote sensing system contains three major elements: the antenna, the radiometer, and the spectrometer. The radiometer consists of the local oscillator, the mixer, and the intermediate frequency amplifiers. This subsystem performs the function of down converting the high frequency incident thermal emission signal to a lower intermediate frequency. The spectrometer measures the power spectrum of the down-converted signal simultaneously in many contiguous frequency channels. Typical spectrum analysis requirements involve measurement of signal bandwidths of 100 to 1000 MHz with a channel resolution of 0.5 to 10 MHz. Three general approaches are used for spectrometers: (1) filter banks, (2) Acousto-Optic Spectrometers (AOS's), and (3) digital autocorrelators. In contrast to the two frequency domain techniques, an autocorrelator works in the time domain. The autocorrelation function (ACF) of the incoming signal is computed and averaged over the integration time. The averaged ACF is then Fourier transformed to obtain the signal power spectrum. Significant progress was made in the development of sub mm antennas and radiometers. It is now time to begin research in the development of low power spaceborne spectrometers and to reduce their size and weight. The near-term research goal will be to develop a prototype digital autocorrelation spectrometer, using VLSI gate array technology, which will have a small size, low power requirements, and can be used in spacecraft mm and sub mm radiometer systems. The long-range objective of this technology development is to make extremely low power, less than 10 mW/channel, small and stable wideband spectrometers which can be used in future mm and sub mm wavelength space missions such as the Large Deployable Reflector.

  14. Spectrometer technology recommendations

    NASA Technical Reports Server (NTRS)

    Wilson, William J.

    1988-01-01

    A typical heterodyne remote sensing system contains three major elements: the antenna, the radiometer, and the spectrometer. The radiometer consists of the local oscillator, the mixer, and the intermediate frequency amplifiers. This subsystem performs the function of down converting the high frequency incident thermal emission signal to a lower intermediate frequency. The spectrometer measures the power spectrum of the down-converted signal simultaneously in many contiguous frequency channels. Typical spectrum analysis requirements involve measurement of signal bandwidths of 100 to 1000 MHz with a channel resolution of 0.5 to 10 MHz. Three general approaches are used for spectrometers: (1) filter banks, (2) Acousto-Optic Spectrometers (AOS's), and (3) digital autocorrelators. In contrast to the two frequency domain techniques, an autocorrelator works in the time domain. The autocorrelation function (ACF) of the incoming signal is computed and averaged over the integration time. The averaged ACF is then Fourier transformed to obtain the signal power spectrum. Significant progress was made in the development of sub mm antennas and radiometers. It is now time to begin research in the development of low power spaceborne spectrometers and to reduce their size and weight. The near-term research goal will be to develop a prototype digital autocorrelation spectrometer, using VLSI gate array technology, which will have a small size, low power requirements, and can be used in spacecraft mm and sub mm radiometer systems. The long-range objective of this technology development is to make extremely low power, less than 10 mW/channel, small and stable wideband spectrometers which can be used in future mm and sub mm wavelength space missions such as the Large Deployable Reflector.

  15. Remote Active Spectrometer

    NASA Astrophysics Data System (ADS)

    Cernius, J. V.; Elser, D. A.; Fox, J.

    1989-01-01

    The Remote Active Spectrometer is a compact, lightweight sensor designed to demonstrate remote detection of chemical vapors. A prototype model was developed by Hughes Aircraft Company for the U.S. Army's Center For Night Vision and Electro-Optics, and the Chemical Research Development and Engineering Center. The Remote Active Spectrometer is comprised of four, frequency agile, CO2 laser transmitters (each operating at a rate of 10 hertz), optics for transmission, pointing, reception, and calibration, and detectors and electronics for information processing and recording. To provide a visual record of the scene observed a TV Sensor is integrated with the system. In this paper the Remote Active Spectrometer is described, and its performance in the field discussed.

  16. Electron-proton spectrometer

    NASA Technical Reports Server (NTRS)

    Winckler, J. R.

    1973-01-01

    An electron-proton spectrometer was designed to measure the geomagnetically trapped radiation in a geostationary orbit at 6.6 earth radii in the outer radiation belt. This instrument is to be flown on the Applications Technology Satellite-F (ATS-F). The electron-proton spectrometer consists of two permanent magnet surface barrier detector arrays and associated electronics capable of selecting and detecting electrons in three energy ranges: (1) 30-50 keV, (2) 150-200 keV, and (3) 500 keV and protons in three energy ranges. The electron-proton spectrometer has the capability of measuring the fluxes of electrons and protons in various directions with respect to the magnetic field lines running through the satellite. One magnet detector array system is implemented to scan between EME north and south through west, sampling the directional flux in 15 steps. The other magnet-detector array system is fixed looking toward EME east.

  17. Comparison of imaging spectrometers

    SciTech Connect

    Bennett, C

    2000-01-09

    Realistic signal to noise performance estimates for the various types of instruments being considered for NGST are compared, based on the point source detection values quoted in the available ISIM final reports. The corresponding sensitivity of the various types of spectrometers operating in a full field imaging mode, for both emission line objects and broad spectral distribution objects, is computed and displayed. For the purpose of seeing the earliest galaxies, or the faintest possible emission line sources, the imaging Fourier transform spectrometer emerges superior to all others, by orders of magnitude in speed.

  18. The Apollo Alpha Spectrometer.

    NASA Technical Reports Server (NTRS)

    Jagoda, N.; Kubierschky, K.; Frank, R.; Carroll, J.

    1973-01-01

    Located in the Science Instrument Module of Apollo 15 and 16, the Alpha Particle Spectrometer was designed to detect and measure the energy of alpha particles emitted by the radon isotopes and their daughter products. The spectrometer sensor consisted of an array of totally depleted silicon surface barrier detectors. Biased amplifier and linear gate techniques were utilized to reduce resolution degradation, thereby permitting the use of a single 512 channel PHA. Sensor identification and in-flight radioactive calibration were incorporated to enhance data reduction.

  19. Portable reflectance spectrometer

    NASA Technical Reports Server (NTRS)

    Goetz, A. F. H.; Graham, R. A.; Ozawa, T. (Inventor)

    1977-01-01

    A portable reflectance spectrometer is disclosed. The spectrometer essentially includes an optical unit and an electronic recording unit. The optical unit includes a pair of thermoelectrically-cooled detectors, for detecting total radiance and selected radiance projected through a circular variable filter wheel, and is capable of operating to provide spectral data in the range 0.4 to 2.5 micrometers without requiring coventional substitution of filter elements. The electronic recording unit includes power supplies, amplifiers, and digital recording electronics designed to permit recordation of data on tape casettes. Both the optical unit and electronic recording unit are packaged to be manually portable.

  20. Broad band waveguide spectrometer

    DOEpatents

    Goldman, Don S.

    1995-01-01

    A spectrometer for analyzing a sample of material utilizing a broad band source of electromagnetic radiation and a detector. The spectrometer employs a waveguide possessing an entry and an exit for the electromagnetic radiation emanating from the source. The waveguide further includes a surface between the entry and exit portions which permits interaction between the electromagnetic radiation passing through the wave guide and a sample material. A tapered portion forms a part of the entry of the wave guide and couples the electromagnetic radiation emanating from the source to the waveguide. The electromagnetic radiation passing from the exit of the waveguide is captured and directed to a detector for analysis.

  1. The Apollo Alpha Spectrometer.

    NASA Technical Reports Server (NTRS)

    Jagoda, N.; Kubierschky, K.; Frank, R.; Carroll, J.

    1973-01-01

    Located in the Science Instrument Module of Apollo 15 and 16, the Alpha Particle Spectrometer was designed to detect and measure the energy of alpha particles emitted by the radon isotopes and their daughter products. The spectrometer sensor consisted of an array of totally depleted silicon surface barrier detectors. Biased amplifier and linear gate techniques were utilized to reduce resolution degradation, thereby permitting the use of a single 512 channel PHA. Sensor identification and in-flight radioactive calibration were incorporated to enhance data reduction.

  2. The GRIFFIN spectrometer

    NASA Astrophysics Data System (ADS)

    Svensson, C. E.; Garnsworthy, A. B.

    2014-01-01

    Gamma-Ray Infrastructure For Fundamental Investigations of Nuclei (GRIFFIN) is an advanced new high-efficiency γ-ray spectrometer being developed for use in decay spectroscopy experiments with low-energy radioactive ion beams provided by TRIUMF's Isotope Separator and Accelerator (ISAC-I) radioactive ion beam facility. GRIFFIN will be comprised of sixteen large-volume clover-type high-purity germanium (HPGe) γ-ray detectors coupled to custom digital signal processing electronics and used in conjunction with a suite of auxiliary detection systems. This article provides an overview of the GRIFFIN spectrometer and its expected performance characteristics.

  3. Miniaturised TOF mass spectrometer

    NASA Astrophysics Data System (ADS)

    Rohner, U.; Wurz, P.; Whitby, J.

    2003-04-01

    For the BepiColombo misson of ESA to Mercury, we built a prototype of a miniaturised Time of Flight mass spectrometer with a low mass and low power consumption. Particles will be set free form the surface and ionized by short laser pluses. The mass spectrometer is dedicated to measure the elemental and isotopic composition of almost all elements of Mercurys planetary surface with an adequate dynamique range, mass range and mass resolution. We will present first results of our prototype and future designs.

  4. Barrel maturation, oak alternatives and micro-oxygenation: influence on red wine aging and quality.

    PubMed

    Oberholster, A; Elmendorf, B L; Lerno, L A; King, E S; Heymann, H; Brenneman, C E; Boulton, R B

    2015-04-15

    The impact of micro-oxygenation (MOX) in conjunction with a variety of oak alternatives on phenolic composition and red wine aging was investigated and compared with traditional barrel aging. Although several studies concluded that MOX give similar results to barrel aging, few have compared them directly and none directly compared MOX with and without wood alternatives and barrel aging. Results confirmed that MOX had a positive effect on colour density, even after 5 months of bottle aging. This is supported by an increase in polymeric phenol and pigment content not only with aging but in the MOX compared to barrel matured wine treatments. Descriptive analysis showed that MOX in combination with wood alternatives such as oak chips and staves could mimic short term (six months) barrel aging in new American and French oak barrels in regards to sensory characteristics.

  5. Recent advances in the evaluation of the oxygen transfer rate in oak barrels.

    PubMed

    del Alamo-Sanza, María; Nevares, Ignacio

    2014-09-03

    The entry of atmospheric oxygen into wine barrels is a desirable characteristic of the wine aging process. The oxygen transfer rate regulates changes in wine affecting aging rates because some barrels may undergo a greater wine oxygenation. This study measured the transfer rate and oxygen distribution within a barrel. The analysis confirmed the presence of a dissolved oxygen concentration gradient in the liquid, with greater concentrations near the bung. The study of the transfer rate of oxygen over time, in 12 barrels of different types, showed that wetting wood reduces oxygen diffusion and the oxygen transfer rate (OTR). These results are the first to determine the kinetics of oxygen entry into wine barrels and can be used to quantify the annual rate of oxygen entry into wine barrels.

  6. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2012-12-26

    Arrival of the RRS Ernest Shackleton near Halley Research Station in Antarctica. The Shackleton is the regular resupply ship for the station and it also brought in some of the BARREL team scientists. The long tether is for the ship’s mooring. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch

  7. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2012-12-25

    An emperor penguin waddles away on Christmas morning in Antarctica. On Christmas day, the BARREL team visited a penguin colony. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through

  8. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2013-01-30

    Watching a BARREL balloon – and the instruments dangling below – float up over the SANAE IV research base in Antarctica. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four

  9. Processing of Niobium-Lined M240 Machine Gun Barrels

    DTIC Science & Technology

    2014-11-01

    produce at least a 0.001 inch (0.025 mm) expansion of the steel cylinder to allow the mandrel to fit inside the liner . The other dimensions were...barrel blank and niobium liner is shown in Fig. 2. 4 Fig. 2 Gun tube and niobium- liner hardware 3. Experimental Approach 3.1 Load Cylinder ...The load cylinder outer diameter was taken to be 0.308 inch (7.82 mm), giving enough clearance between it and the niobium liner to ensure easy

  10. Optical System of the STAR Barrel Electromagnetic Calorimeter

    NASA Astrophysics Data System (ADS)

    Grachov, O. A.

    2000-04-01

    The STAR Barrel Electromagnetic Calorimeter(BEMC) is a sampling calorimeter and the core of structure consist of a lead-scintillator plate stack. The plastic scintillator in the form of Mega-tile with 40 optically isolated tiles in each layer. The tile/fiber system uses a wavelength shifting fiber to read out the signal of a tile and a optical clear fiber carry the light through the magnet structure to the electronic-PMT box. A discription of the Optical system of BEMC is presented along with a current status of the quality control program of the calorimeter production.

  11. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-09-27

    The BARREL team at the SANAE IV research station celebrates their final launch in the Antarctica sun. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors

  12. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-09-27

    BARREL team members run under the payload as the balloon first takes flight at the SANAE IV research station in Antarctica. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four

  13. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-09-27

    A BARREL balloon floats into the sky as it is partially filled. When fully inflated, each balloon is 90 feet in diameter and carries an instrument suite that weighs 50 pounds. This is small for an Antarctica balloon launch, which can have balloons Typical balloons l the size of a football field with payloads of some 3,000 pounds. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in

  14. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-09-27

    An iceberg as viewed from the bow of the RRS Ernest Shackleton a few days before the BARREL team reached Halley Research Station in Antarctica. This research vessel regularly carries scientists and supplies to Halley. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014

  15. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-09-27

    Some of the BARREL balloon launches took place at the South African National Antarctic Expedition Research base, called SANAE IV, the others at Halley Research Station. This balloon is taking flight at SANAE IV. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA

  16. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-09-27

    Pumping helium into the first BARREL balloon to launch from Halley Research Satation. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science

  17. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-09-27

    A crane lowers two BARREL balloon payloads onto the platform at Halley Research Station in Antarctica. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors

  18. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2017-09-27

    The BARREL cargo on its four-hour journey from the supply ship to the research station. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science

  19. Innovative active control of gun barrels using smart materials

    NASA Astrophysics Data System (ADS)

    Mattice, Michael S.; LaVigna, Chris

    1997-06-01

    The accuracy of stabilized, turreted gun systems like the 120mm gun on the M1A2 Abrams tank and the 30mm gun on the Apache helicopter are limited by, among other things, structural flexure of the gun barrel and support structure. An advanced actuation system based on piezoelectric translators and an optical fiber strain sensing system are described in conjunction with a rapid prototyping workstation for the design of distributed parameter control systems to actively minimize the effects of vibrations caused by traversing rough terrain or weapon firing.

  20. Theoretical Exploration of Barrel-Shaped Drops on Cactus Spines.

    PubMed

    Luo, Cheng

    2015-11-03

    To survive an arid environment, desert cacti are capable of harvesting water from fog by transporting condensed water drops using their spines. Cactus spines have a conical shape. In this work, on the basis of the difference of liquid pressure, a new theoretical model has been developed for a barrel-shaped liquid drop on a conical wire. This model is further simplified to interpret the effects of contact angles, conical angle, surface microgrooves, and gravity on the drop movement along a cactus spine.

  1. Experience-dependent regulation of NG2 progenitors in the developing barrel cortex

    PubMed Central

    Mangin, Jean-Marie; Li, Peijun; Scafidi, Joseph; Gallo, Vittorio

    2012-01-01

    We show that during formation of the mouse barrel cortex, NG2 cells receive glutamatergic synapses from thalamocortical fibers and preferentially accumulate along septa separating the barrels. Sensory deprivation reduces thalamocortical inputs on NG2 cells and increases their proliferation, leading to a more uniform distribution within the deprived barrels. Therefore, early sensory experience regulates thalamocortical innervation on NG2 cells, as well as their proliferation and distribution during development. PMID:22885848

  2. Mechanical and Thermal Properties of Advanced Ceramics for Gun Barrel Applications

    DTIC Science & Technology

    2005-02-01

    Mechanical and Thermal Properties of Advanced Ceramics for Gun Barrel Applications by Jeffrey J. Swab, Andrew A. Wereszczak, Jason Tice, Russ... Barrel Applications Jeffrey J. Swab, Andrew A. Wereszczak, Jason Tice, Russ Caspe, Reuben H. Kraft, and Jane W. Adams Weapons and Materials Research...Ceramics for Gun Barrel Applications 5c. PROGRAM ELEMENT NUMBER 5d. PROJECT NUMBER 622618.H80 5e. TASK NUMBER 6. AUTHOR(S) Jeffrey J. Swab

  3. Friction Stir Welding of the Space Shuttle External Tank Longitudinal Barrel Welds

    NASA Technical Reports Server (NTRS)

    Adams, Glynn; Pareti, Paul; Thompson, Jack; Lawless, Kirby; Munafo, Paul M. (Technical Monitor)

    2001-01-01

    Through the implementation of friction stir welding, the safety, reliability, and producibility of the external tank is enhanced. Such fusion procedures are accomplished with the use of a short barrel weld tool or a long barrel weld tool. Forecasted developments in the fusion tooling field include the advent of a universal tool which is capable to fusing all barrel configurations. A wide array of mechanical and electrical controls are described for such a device.

  4. Novel interference spectrometer

    NASA Astrophysics Data System (ADS)

    Chen, Weiwen; Lin, Zhong; Zhang, Zhilian

    1994-01-01

    A modification of the conventional Michelson interference spectrometer is proposed that replaces the extremely precise translational motion with a single uniform velocity rotation of one perpendicular double mirror. The formulas of the optical path difference and the light displacement are deduced. The calculated data show that the path difference has good linearity with the rotation angle. The characteristics of this design are also analyzed.

  5. Mass Spectrometers in Space!

    NASA Technical Reports Server (NTRS)

    Brinckerhoff, William B.

    2012-01-01

    Exploration of our solar system over several decades has benefitted greatly from the sensitive chemical analyses offered by spaceflight mass spectrometers. When dealing with an unknown environment, the broadband detection capabilities of mass analyzers have proven extremely valuable in determining the composition and thereby the basic nature of space environments, including the outer reaches of Earth s atmosphere, interplanetary space, the Moon, and the planets and their satellites. Numerous mass analyzer types, including quadrupole, monopole, sector, ion trap, and time-of-flight have been incorporated in flight instruments and delivered robotically to a variety of planetary environments. All such instruments went through a rigorous process of application-specific development, often including significant miniaturization, testing, and qualification for the space environment. Upcoming missions to Mars and opportunities for missions to Venus, Europa, Saturn, Titan, asteroids, and comets provide new challenges for flight mass spectrometers that push to state of the art in fundamental analytical technique. The Sample Analysis at Mars (SAM) investigation on the recently-launch Mars Science Laboratory (MSL) rover mission incorporates a quadrupole analyzer to support direct evolved gas as well as gas chromatograph-based analysis of martian rocks and atmosphere, seeking signs of a past or present habitable environment. A next-generation linear ion trap mass spectrometer, using both electron impact and laser ionization, is being incorporated into the Mars Organic Molecule Analyzer (MOMA) instrument, which will be flown to Mars in 2018. These and other mass spectrometers and mission concepts at various stages of development will be described.

  6. Oak wine barrel as an active vessel: A critical review of past and current knowledge.

    PubMed

    Del Alamo-Sanza, Maria; Nevares, Ignacio

    2017-05-30

    We review the role of the oak barrel as an active vessel for wine maturation. We present a historical background to highlight that previously established aspects of processes occurring with wine inside the oak barrel are still without confirmation. We argue that recently published new findings on the topic are determining factors in defining the manner in which the oak barrel works with wine. Several studies have been published reviewing how the wine barrel functions as an active vessel that releases chemical compounds into the wine, improving its physical, chemical, and sensory properties. Nevertheless, there are hardly any studies that describe how a wine barrel functions as an active vessel. The present review details the main factors affecting the gas exchange capacity of the barrel, such as the pressure drop generated within the barrel, the formation of a headspace, the effect of wood anatomy, the different oxygen entry routes, the role of wood moisture content and soluble ellagitannins, and the effect of barrel toasting on cooperage. Finally, a hypothesis is proposed regarding the function of the barrel as an active vessel, which determines the manner in which it interacts with the wine that it contains during aging.

  7. Drag Measurements of a Protruding .50-caliber Machine Gun with Barrel Jacket Removed

    NASA Technical Reports Server (NTRS)

    Luoma, Arvo A.

    1943-01-01

    Tests were made in 8-ft high-speed wind tunnel to determine the drag reduction possible by eliminating the barrel jacket of a protruding 50-caliber aircraft gun. It was found that the drag of a standard aircraft gun protruding into the air stream at right angles to the flow can be reduced by 23% by discarding the barrel jacket. At 300 mph and sea-level conditions, this amounts to a decrease in drag of from 83 to 64 pounds. A rough surface finish on the barrel was found to have no adverse effects on the drag of the barrel, the drag being actually less at high Mach Numbers.

  8. Dynamic response of a lightweight gun barrel during a firing-pressure transient

    SciTech Connect

    McGrath, S.V.; Phillips, L.P. Jr.

    1990-04-01

    This report presents the results of a nonlinear, dynamic structural analysis of a gun barrel design during a firing-pressure transient. The final design was defined by an iterative design/analysis process in which the effects of design modifications were compared with established design criteria. The ADINA finite element code was used to analyze the titanium/carbon composite gun barrel assembly for a maximum transient pressure of 29,000 psi. The gun barrel weighs 42 lb; however, a significant potential exists for weight savings in future gun barrel designs. 2 refs., 41 figs.

  9. Parallel access alignment network with barrel switch implementation for d-ordered vector elements

    NASA Technical Reports Server (NTRS)

    Barnes, George H. (Inventor)

    1980-01-01

    An alignment network between N parallel data input ports and N parallel data outputs includes a first and a second barrel switch. The first barrel switch fed by the N parallel input ports shifts the N outputs thereof and in turn feeds the N-1 input data paths of the second barrel switch according to the relationship X=k.sup.y modulo N wherein x represents the output data path ordering of the first barrel switch, y represents the input data path ordering of the second barrel switch, and k equals a primitive root of the number N. The zero (0) ordered output data path of the first barrel switch is fed directly to the zero ordered output port. The N-1 output data paths of the second barrel switch are connected to the N output ports in the reverse ordering of the connections between the output data paths of the first barrel switch and the input data paths of the second barrel switch. The second switch is controlled by a value m, which in the preferred embodiment is produced at the output of a ROM addressed by the value d wherein d represents the incremental spacing or distance between data elements to be accessed from the N input ports, and m is generated therefrom according to the relationship d=k.sup.m modulo N.

  10. Oak Stave Oxygen Permeation: A New Tool To Make Barrels with Different Wine Oxygenation Potentials.

    PubMed

    Nevares, Ignacio; Del Alamo-Sanza, María

    2015-01-22

    The aim of this study was to classify rough staves according to their permeability to oxygen by measuring their transmission rate to assess the capacity to build barrels with high and low oxygen transmission rates (OTRs). The ability to assess the OTR would be important for better understanding and controlling the aging process of wine in barrels. To accomplish this, we built a device that measures the OTR of rough staves under the same conditions as those in a full barrel, in which the stave is in contact with a liquid solution on one face and with a diffusing gas on the opposite face. A total of 69 rough staves were classified to yield a high-OTR group, with a mean 2.6 times higher than the mean of the low-OTR group. A high-OTR barrel and a low-OTR barrel were constructed, and we confirmed that the stave OTR decreased between 3- and 4.5-fold in the barrels and that the high-OTR barrel allowed the entry of twice the concentration of oxygen compared to the low-OTR barrel. These results confirmed the capacity to classify rough staves and build barrels with different OTRs.

  11. Fabrication of a metal-cored multi-barrelled microiontophoresis assembly.

    PubMed

    Hellier, M; Boers, P; Lambert, G A

    1990-04-01

    A method is described for fabrication of 7-barrelled microiontophoresis electrodes with a center barrel of platinum-coated tungsten. The electrodes require a minimum of expensive apparatus and can be fabricated in an hour or two. The electrodes have low recording impedance (typically 100 k omega and low resistance iontophoresis barrels (typically 20-50 M omega). Compared to electrodes with a micropipette recording barrel, these electrodes are practically noise-free and can pass ionotophoretic currents of up to 200 nA without an appreciable increase in recording noise.

  12. Creation of active TIM barrel enzymes through genetic fusion of half-barrel domain constructs derived from two distantly related glycosyl hydrolases.

    PubMed

    Sharma, Prerna; Kaila, Pallavi; Guptasarma, Purnananda

    2016-12-01

    Diverse unrelated enzymes that adopt the beta/alpha (or TIM) barrel topology display similar arrangements of beta/alpha units placed in a radial eight-fold symmetry around the barrel's axis. The TIM barrel was originally thought to be a single structural domain; however, it is now thought that TIM barrels arose from duplication and fusion of smaller half-barrels consisting of four beta/alpha units. We describe here the design, expression and purification, as well as characterization of folding, activity and stability, of chimeras of two TIM barrel glycosyl hydrolases, made by fusing different half-barrel domains derived from an endoglucanase from Clostridium cellulolyticum, CelCCA and a beta-glucosidase from Pyrococcus furiosus, CelB. We show that after refolding following purification from inclusion bodies, the two half-barrel fusion chimeras (CelCCACelB and CelBCelCCA) display catalytic activity although they assemble into large soluble oligomeric aggregated species containing chains of mixed beta and alpha structure. CelBCelCCA displays hyperthermophile-like structural stability as well as significant stability to chemical denaturation (Cm of 2.6 m guanidinium hydrochloride), whereas CelCCACelB displays mesophile-like stability (Tm of ~ 71 °C). The endoglucanase activities of both chimeras are an order of magnitude lower than those of CelB or CelCCA, whereas the beta-glucosidase activity of CelBCelCCA is about two orders of magnitude lower than that of CelB. The chimera CelCCACelB shows no beta-glucosidase activity. Our results demonstrate that half-barrel domains from unrelated sources can fold, assemble and function, with scope for improvement.

  13. EMIC Waves Observed in Conjunction with BARREL Electron Precipitation

    NASA Astrophysics Data System (ADS)

    Weaver, C.; Engebretson, M. J.; Lessard, M.; Halford, A. J.; Millan, R. M.; Horne, R. B.; Singer, H. J.

    2013-05-01

    Electromagnetic ion-cyclotron (EMIC) waves have been detected at Halley, Antarctica coinciding with observations of electron precipitation on high altitude balloons from the Balloon Array for RBSP Relativistic Electron Losses (BARREL) campaign launched in early 2013 from SANAE IV and Halley Station. The balloons were launched such that both spatial and temporal properties of electron precipitation might be examined. With a magnetic foot point mapped to the radiation belts, Halley is an ideal location to capture ground based signatures that coincide with electron precipitation. EMIC waves have been shown, both theoretically and through statistical surveys, to pitch angle scatter energetic protons and relativistic electrons via cyclotron resonance and contribute to radiation belt dynamics. EMIC waves were detected at Halley Station 23 times from 12 Jan - 4 Feb with 17 of those waves occurring during times when at least one BARREL balloon observed precipitation in one or more energy channels. High resolution magnetometer data from GOES 13 (which has a magnetic foot point near WAIS Divide, Antarctica-located about 2.5 hours, in MLT, west of Halley) show similar EMIC wave structure and frequency to 9 waves observed at Halley, suggesting the source region extended to at least the longitude and L value of GOES 13 during some events. The ground observed waves appeared in all local times and during both quiet and disturbed intervals.

  14. Double Barrel In Situ Recanalization of Thrombosed Nonretrievable IVC filter.

    PubMed

    Banerjee, Shubhabrata; Patel, Hiten M; Sheorain, Virender K; Grover, Tarun; Parakh, Rajiv

    2016-05-01

    We report a case of endovascular recanalization of complete thrombotic occlusion of the inferior vena cava (IVC) and bilateral iliac veins using the architectural knowledge of the in situ permanent IVC filter in a 23-year-old male. The infrarenal permanent IVC filter was TRAPEASE permanent vena cava filter (Cordis) placed at an outstation hospital for pulmonary embolism. Being permanent variant of filter, percutaneous removal was not possible. The patient had severe venous claudication and an attempt to recanalize the blocked filter was considered, in view of the age no justifiable indication for a long-term filter. After pharmacomechanical catheter-directed thrombolysis, there was residual focal flow-limiting thrombus within the filter. The design of the Trapease Cordis filter was instrumental in our decision to attempt to recanalize the filter in situ using 2 parallel stents with the filter struts as anchoring pillars in a double-barrel alignment. In similar cases of persistent Trapease filter-related thrombotic occlusion of the IVC, this double barrel in situ recanalization shall be a viable alternative to the well-described technique of crushing the filter and recanalizing it with a single stent.

  15. Tropospheric and Airborne Emission Spectrometers

    NASA Technical Reports Server (NTRS)

    Glavich, Thomas; Beer, Reinhard

    1996-01-01

    X This paper describes the development of two related instruments, the Tropospheric Emission Spectrometer (TES) and the Airborne Emission Spectrometer (AES). Both instruments are infrared imaging Fourier Transform Spectrometers, used for measuring the state of the lower atmosphere, and in particular the measurement of ozone and ozone sources and sinks.

  16. Smartphone spectrometer for colorimetric biosensing.

    PubMed

    Wang, Yi; Liu, Xiaohu; Chen, Peng; Tran, Nhung Thi; Zhang, Jinling; Chia, Wei Sheng; Boujday, Souhir; Liedberg, Bo

    2016-05-23

    We report on a smartphone spectrometer for colorimetric biosensing applications. The spectrometer relies on a sample cell with an integrated grating substrate, and the smartphone's built-in light-emitting diode flash and camera. The feasibility of the smartphone spectrometer is demonstrated for detection of glucose and human cardiac troponin I, the latter in conjunction with peptide-functionalized gold nanoparticles.

  17. Grille spectrometer (grille)

    NASA Technical Reports Server (NTRS)

    Ackerman, M.; Besson, J.

    1988-01-01

    The Grille spectrometer was designed and flown on Spaceklab 1 by two organizations: The Office National d'Etudes et de Recherches Aerospatiales in France and the Belgian Institute for Space Aeronomy in Belgium. Its purpose is to study, on a global scale, atmospheric parameters between 15 and 150 km altitude. The investigation uses high-resolution (better than 0.1/cm) spectroscopic observations of the earth's limb in the wavelength range characteristic of the vibrational-rotational lines of the relevant atmospheric constituents. Characteristics and proposed modifications of the grille spectrometer are described. This instrument will be part of the atmospheric science research payload flown on the Atmospheric Laboratory for Applications and Science (ATLAS 1) NASA mission planned for late 1990.

  18. FAST NEUTRON SPECTROMETER

    DOEpatents

    Davis, F.J.; Hurst, G.S.; Reinhardt, P.W.

    1959-08-18

    An improved proton recoil spectrometer for determining the energy spectrum of a fast neutron beam is described. Instead of discriminating against and thereby"throwing away" the many recoil protons other than those traveling parallel to the neutron beam axis as do conventional spectrometers, this device utilizes protons scattered over a very wide solid angle. An ovoidal gas-filled recoil chamber is coated on the inside with a scintillator. The ovoidal shape of the sensitive portion of the wall defining the chamber conforms to the envelope of the range of the proton recoils from the radiator disposed within the chamber. A photomultiplier monitors the output of the scintillator, and a counter counts the pulses caused by protons of energy just sufficient to reach the scintillator.

  19. The ALPHA Magnetic Spectrometer

    NASA Astrophysics Data System (ADS)

    Viertel, G. M.; Capell, M.

    1998-12-01

    The ALPHA Magnetic Spectrometer (AMS) will be the first large magnetic spectrometer in space. It is scheduled to be installed on the future International Space Station ALPHA (ISSA) in the year 2002 to perform measurements of the charged particle composition to answer fundamental questions in particle physics and astrophysics. Before installation on ISSA, AMS will fly on the shuttle DISCOVERY for a period of 10 days starting in May 1998. This will enable AMS to perform a test of the apparatus and first measurements. The AMS detector has five major components: A permanent NdFeB magnet, six planes of Silicon double-sided microstrip detectors, a plastic scintillator time of flight hodoscope, a plastic scintillator anticoincidence counter and an Aerogel Cherenkov threshold counter. In addition, there are electronics, support infrastructure and interfaces.

  20. Imaging Fourier Transform Spectrometer

    SciTech Connect

    Bennett, C.L.; Carter, M.R.; Fields, D.J.; Hernandez, J.

    1993-04-14

    The operating principles of an Imaging Fourier Transform Spectrometer (IFTS) are discussed. The advantages and disadvantages of such instruments with respect to alternative imaging spectrometers are discussed. The primary advantages of the IFTS are the capacity to acquire more than an order of magnitude more spectral channels than alternative systems with more than an order of magnitude greater etendue than for alternative systems. The primary disadvantage of IFTS, or FTS in general, is the sensitivity to temporal fluctuations, either random or periodic. Data from the IRIFTS (ir IFTS) prototype instrument, sensitive in the infrared, are presented having a spectral sensitivity of 0.01 absorbance units, a spectral resolution of 6 cm{sup {minus}1} over the range 0 to 7899 cm{sup {minus}1}, and a spatial resolution of 2.5 mr.

  1. A Sagnac Fourier spectrometer

    DOE PAGES

    Lenzner, Matthias; Diels, Jean -Claude

    2017-03-09

    A spectrometer based on a Sagnac interferometer, where one of the mirrors is replaced by a transmission grating, is introduced. Since the action of a transmission grating is reversible, both directions experience the same diffraction at a given wavelength. At the output, the crossed wavefronts are imaged onto a camera, where their Fizeau fringe pattern is recorded. Each spectral element produces a unique spatial frequency, hence the Fourier transform of the recorded interferogram contains the spectrum. Since the grating is tuned to place zero spatial frequency at a selected wavelength, the adjoining spectrum is heterodyned with respect to this wavelength.more » This spectrum can then be discriminated at a high spectral resolution from relatively low spatial frequencies. The spectrometer can be designed without moving parts for a relatively narrow spectral range or with a rotatable grating. As a result, the latter version bears the potential to be calibrated without a calibrated light source.« less

  2. Surface Plasmon Based Spectrometer

    NASA Astrophysics Data System (ADS)

    Wig, Andrew; Passian, Ali; Boudreaux, Philip; Ferrell, Tom

    2008-03-01

    A spectrometer that uses surface plasmon excitation in thin metal films to separate light into its component wavelengths is described. The use of surface plasmons as a dispersive medium sets this spectrometer apart from prism, grating, and interference based variants and allows for the miniaturization of this device. Theoretical and experimental results are presented for two different operation models. In the first case surface plasmon tunneling in the near field is used to provide transmission spectra of different broad band-pass, glass filters across the visible wavelength range with high stray-light rejection at low resolution as well as absorption spectra of chlorophyll extracted from a spinach leaf. The second model looks at the far field components of surface plasmon scattering.

  3. Galileo Ultraviolet Spectrometer experiment

    NASA Technical Reports Server (NTRS)

    Hord, C. W.; Mcclintock, W. E.; Stewart, A. I. F.; Barth, C. A.; Esposito, L. W.; Thomas, G. E.; Sandel, B. R.; Hunten, D. M.; Broadfoot, A. L.; Shemansky, D. E.

    1992-01-01

    The Galileo ultraviolet spectrometer experiment uses data obtained by the Ultraviolet Spectrometer (UVS) mounted on the pointed orbiter scan platform and from the Extreme Ultraviolet Spectrometer (EUVS) mounted on the spinning part of the orbiter with the field of view perpendicular to the spin axis. The UVS is a Ebert-Fastie design that covers the range 113-432 nm with a wavelength resolution of 0.7 nm below 190 and 1.3 nm at longer wavelengths. The UVS spatial resolution is 0.4 deg x 0.1 deg for illuminated disk observations and 1 deg x 0.1 deg for limb geometries. The EUVS is a Voyager design objective grating spectrometer, modified to cover the wavelength range from 54 to 128 nm with wavelength resolution 3.5 nm for extended sources and 1.5 nm for point sources and spatial resolution of 0.87 deg x 0.17 deg. The EUVS instrument will follow up on the many Voyager UVS discoveries, particularly the sulfur and oxygen ion emissions in the Io torus and molecular and atomic hydrogen auroral and airglow emissions from Jupiter. The UVS will obtain spectra of emission, absorption, and scattering features in the unexplored, by spacecraft, 170-432 nm wavelength region. The UVS and EUVS instruments will provide a powerful instrument complement to investigate volatile escape and surface composition of the Galilean satellites, the Io plasma torus, micro- and macro-properties of the Jupiter clouds, and the composition structure and evolution of the Jupiter upper atmosphere.

  4. Miniaturized Ion Mobility Spectrometer

    NASA Technical Reports Server (NTRS)

    Kaye, William J (Inventor); Stimac, Robert M. (Inventor)

    2017-01-01

    By utilizing the combination of a unique electronic ion injection control circuit in conjunction with a particularly designed drift cell construction, the instantly disclosed ion mobility spectrometer (IMS) achieves increased levels of sensitivity, while achieving significant reductions in size and weight. The instant IMS is of a much simpler and easy to manufacture design, rugged and hermetically sealed, capable of operation at high temperatures to at least 250 degrees Centigrade, and is uniquely sensitive, particularly to explosive chemicals.

  5. Miniaturized Ion Mobility Spectrometer

    NASA Technical Reports Server (NTRS)

    Kaye, William J. (Inventor); Stimac, Robert M. (Inventor)

    2015-01-01

    By utilizing the combination of a unique electronic ion injection control circuit in conjunction with a particularly designed drift cell construction, the instantly disclosed ion mobility spectrometer achieves increased levels of sensitivity, while achieving significant reductions in size and weight. The instant IMS is of a much simpler and easy to manufacture design, rugged and hermetically sealed, capable of operation at high temperatures to at least 250.degree. C., and is uniquely sensitive, particularly to explosive chemicals.

  6. Demonstration AOTF Imaging Spectrometer

    NASA Technical Reports Server (NTRS)

    Chao, Tien-Hsin; Yu, Jeffrey; Cheng, Li-Jen

    1993-01-01

    Spectral images of high quality obtained. Acousto-optical-tunable-filter (AOTF) imaging spectrometer is optical system in which AOTF serves as spectrally dispersive element causing image on final focal plane to be shifted on plane by distance depending on wavelength of light emanating from scene. Useful in several applications involving identification, via characteristic spectras, of substances in observed scenes: examples include prospecting for minerals and detecting chemical pollutants.

  7. X-ray Spectrometer

    NASA Technical Reports Server (NTRS)

    Porter, F. Scott

    2004-01-01

    The X-ray Spectrometer (XRS) instrument is a revolutionary non-dispersive spectrometer that will form the basis for the Astro-E2 observatory to be launched in 2005. We have recently installed a flight spare X R S microcalorimeter spectrometer at the EBIT-I facility at LLNL replacing the XRS from the earlier Astro-E mission and providing twice the resolution. The X R S microcalorimeter is an x-ray detector that senses the heat deposited by the incident photon. It achieves a high energy resolution by operating at 0.06K and by carefully controlling the heat capacity and thermal conductance. The XRS/EBIT instrument has 32 pixels in a square geometry and achieves an energy resolution of 6 eV at 6 keV, with a bandpass from 0.1 to 12 keV (or more at higher operating temperature). The instrument allows detailed studies of the x-ray line emission of laboratory plasmas. The XRS/EBIT also provides an extensive calibration "library" for the Astro-E2 observatory.

  8. X-ray Spectrometer

    NASA Technical Reports Server (NTRS)

    Porter, F. Scott

    2004-01-01

    The X-ray Spectrometer (XRS) instrument is a revolutionary non-dispersive spectrometer that will form the basis for the Astro-E2 observatory to be launched in 2005. We have recently installed a flight spare X R S microcalorimeter spectrometer at the EBIT-I facility at LLNL replacing the XRS from the earlier Astro-E mission and providing twice the resolution. The X R S microcalorimeter is an x-ray detector that senses the heat deposited by the incident photon. It achieves a high energy resolution by operating at 0.06K and by carefully controlling the heat capacity and thermal conductance. The XRS/EBIT instrument has 32 pixels in a square geometry and achieves an energy resolution of 6 eV at 6 keV, with a bandpass from 0.1 to 12 keV (or more at higher operating temperature). The instrument allows detailed studies of the x-ray line emission of laboratory plasmas. The XRS/EBIT also provides an extensive calibration "library" for the Astro-E2 observatory.

  9. NASA’s BARREL Mission Launches 20 Balloons

    NASA Image and Video Library

    2013-01-04

    Liftoff! A balloon begins to rise over the brand new Halley VI Research Station, which had its grand opening in February 2013. Credit: NASA --- In Antarctica in January, 2013 – the summer at the South Pole – scientists launched 20 balloons up into the air to study an enduring mystery of space weather: when the giant radiation belts surrounding Earth lose material, where do the extra particles actually go? The mission is called BARREL (Balloon Array for Radiation belt Relativistic Electron Losses) and it is led by physicist Robyn Millan of Dartmouth College in Hanover, NH. Millan provided photographs from the team’s time in Antarctica. The team launched a balloon every day or two into the circumpolar winds that circulate around the pole. Each balloon floated for anywhere from 3 to 40 days, measuring X-rays produced by fast-moving electrons high up in the atmosphere. BARREL works hand in hand with another NASA mission called the Van Allen Probes, which travels through the Van Allen radiation belts surrounding Earth. The belts wax and wane over time in response to incoming energy and material from the sun, sometimes intensifying the radiation through which satellites must travel. Scientists wish to understand this process better, and even provide forecasts of this space weather, in order to protect our spacecraft. As the Van Allen Probes were observing what was happening in the belts, BARREL tracked electrons that precipitated out of the belts and hurtled down Earth’s magnetic field lines toward the poles. By comparing data, scientists will be able to track how what’s happening in the belts correlates to the loss of particles – information that can help us understand this mysterious, dynamic region that can impact spacecraft. Having launched balloons in early 2013, the team is back at home building the next set of payloads. They will launch 20 more balloons in 2014. NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through

  10. Mass spectrometers: instrumentation

    NASA Astrophysics Data System (ADS)

    Cooks, R. G.; Hoke, S. H., II; Morand, K. L.; Lammert, S. A.

    1992-09-01

    Developments in mass spectrometry instrumentation over the past three years are reviewed. The subject is characterized by an enormous diversity of designs, a high degree of competition between different laboratories working with either different or similar techniques and by extremely rapid progress in improving analytical performance. Instruments can be grouped into genealogical charts based on their physical and conceptual interrelationships. This is illustrated using mass analyzers of different types. The time course of development of particular instrumental concepts is illustrated in terms of the s-curves typical of cell growth. Examples are given of instruments which are at the exponential, linear and mature growth stages. The prime examples used are respectively: (i) hybrid instruments designed to study reactive collisions of ions with surfaces: (ii) the Paul ion trap; and (iii) the triple quadrupole mass spectrometer. In the area of ion/surface collisions, reactive collisions such as hydrogen radical abstraction from the surface by the impinging ion are studied. They are shown to depend upon the chemical nature of the surface through the use of experiments which utilize self-assembled monolayers as surfaces. The internal energy deposited during surface-induced dissociation upon collision with different surfaces in a BEEQ instrument is also discussed. Attention is also given to a second area of emerging instrumentation, namely technology which allows mass spectrometers to be used for on-line monitoring of fluid streams. A summary of recent improvements in the performance of the rapidly developing quadrupole ion trap instrument illustrates this stage of instrument development. Improvements in resolution and mass range and their application to the characterization of biomolecules are described. The interaction of theory with experiment is illustrated through the role of simulations of ion motion in the ion trap. It is emphasized that mature instruments play a

  11. 15 CFR 241.6 - Classes of barrels for tolerance application.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 1 shall include (1) all barrels no dimension of which is in error by more than the following amounts, and (2) all barrels one or more of the dimensions of which are in error by more than the following amounts, and which in addition have no dimension in error in the opposite direction: Error, inches...

  12. 15 CFR 241.6 - Classes of barrels for tolerance application.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 shall include (1) all barrels no dimension of which is in error by more than the following amounts, and (2) all barrels one or more of the dimensions of which are in error by more than the following amounts, and which in addition have no dimension in error in the opposite direction: Error, inches...

  13. 15 CFR 241.6 - Classes of barrels for tolerance application.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 1 shall include (1) all barrels no dimension of which is in error by more than the following amounts, and (2) all barrels one or more of the dimensions of which are in error by more than the following amounts, and which in addition have no dimension in error in the opposite direction: Error, inches...

  14. 15 CFR 241.6 - Classes of barrels for tolerance application.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 1 shall include (1) all barrels no dimension of which is in error by more than the following amounts, and (2) all barrels one or more of the dimensions of which are in error by more than the following amounts, and which in addition have no dimension in error in the opposite direction: Error, inches...

  15. Tapered laser rods as a means of minimizing the path length of trapped barrel mode rays

    DOEpatents

    Beach, Raymond J.; Honea, Eric C.; Payne, Stephen A.; Mercer, Ian; Perry, Michael D.

    2005-08-30

    By tapering the diameter of a flanged barrel laser rod over its length, the maximum trapped path length of a barrel mode can be dramatically reduced, thereby reducing the ability of the trapped spontaneous emission to negatively impact laser performance through amplified spontaneous emission (ASE). Laser rods with polished barrels and flanged end caps have found increasing application in diode array end-pumped laser systems. The polished barrel of the rod serves to confine diode array pump light within the rod. In systems utilizing an end-pumping geometry and such polished barrel laser rods, the pump light that is introduced into one or both ends of the laser rod, is ducted down the length of the rod via the total internal reflections (TIRs) that occur when the light strikes the rod's barrel. A disadvantage of using polished barrel laser rods is that such rods are very susceptible to barrel mode paths that can trap spontaneous emission over long path lengths. This trapped spontaneous emission can then be amplified through stimulated emission resulting in a situation where the stored energy available to the desired lasing mode is effectively depleted, which then negatively impacts the laser's performance, a result that is effectively reduced by introducing a taper onto the laser rod.

  16. Algorithm and implementation of muon trigger and data transmission system for barrel-endcap overlap region of the CMS detector

    NASA Astrophysics Data System (ADS)

    Zabolotny, W. M.; Byszuk, A.

    2016-03-01

    The CMS experiment Level-1 trigger system is undergoing an upgrade. In the barrel-endcap transition region, it is necessary to merge data from 3 types of muon detectors—RPC, DT and CSC. The Overlap Muon Track Finder (OMTF) uses the novel approach to concentrate and process those data in a uniform manner to identify muons and their transversal momentum. The paper presents the algorithm and FPGA firmware implementation of the OMTF and its data transmission system in CMS. It is foreseen that the OMTF will be subject to significant changes resulting from optimization which will be done with the aid of physics simulations. Therefore, a special, high-level, parameterized HDL implementation is necessary.

  17. A radial map of multi-whisker correlation selectivity in the rat barrel cortex.

    PubMed

    Estebanez, Luc; Bertherat, Julien; Shulz, Daniel E; Bourdieu, Laurent; Léger, Jean-François

    2016-11-21

    In the barrel cortex, several features of single-whisker stimuli are organized in functional maps. The barrel cortex also encodes spatio-temporal correlation patterns of multi-whisker inputs, but so far the cortical mapping of neurons tuned to such input statistics is unknown. Here we report that layer 2/3 of the rat barrel cortex contains an additional functional map based on neuronal tuning to correlated versus uncorrelated multi-whisker stimuli: neuron responses to uncorrelated multi-whisker stimulation are strongest above barrel centres, whereas neuron responses to correlated and anti-correlated multi-whisker stimulation peak above the barrel-septal borders, forming rings of multi-whisker synchrony-preferring cells.

  18. Alcohol dehydrogenase polymorphism in barrel cactus populations of Drosophila mojavensis.

    PubMed

    Cleland, S; Hocutt, G D; Breitmeyer, C M; Markow, T A; Pfeiler, E

    1996-07-01

    Starch gel electrophoresis revealed that the alcohol dehydrogenase (ADH-2) locus was polymorphic in two populations (from Agua Caliente, California and the Grand Canyon, Arizona) of cactophilic Drosophila mojavensis that utilize barrel cactus (Ferocactus acanthodes) as a host plant. Electromorphs representing products of a slow (S) and a fast (F) allele were found in adult flies. The frequency of the slow allele was 0.448 in flies from Agua Caliente and 0.659 in flies from the Grand Canyon. These frequencies were intermediate to those of the low (Baja California peninsula, Mexico) and high (Sonora, Mexico and southern Arizona) frequency Adh-2S populations of D. mojavensis that utilize different species of host cacti.

  19. Performance of the ATLAS electromagnetic calorimeter barrel module 0

    NASA Astrophysics Data System (ADS)

    Aubert, B.; Ballansat, J.; Bazan, A.; Beaugiraud, B.; Boniface, J.; Chollet, F.; Colas, J.; Delebecque, P.; di Ciaccio, L.; Dumont-Dayot, N.; El Kacimi, M.; Gaumer, O.; Ghez, P.; Girard, C.; Gouanère, M.; Kambara, H.; Jérémie, A.; Jézéquel, S.; Lafaye, R.; Leflour, T.; Le Maner, C.; Lesueur, J.; Massol, N.; Moynot, M.; Neukermans, L.; Perrodo, P.; Perrot, G.; Poggioli, L.; Prast, J.; Przysiezniak, H.; Riccadona, X.; Sauvage, G.; Thion, J.; Wingerter-Seez, I.; Zitoun, R.; Zolnierowski, Y.; Chen, H.; Citterio, M.; Farrell, J.; Gordon, H.; Hackenburg, B.; Hoffman, A.; Kierstead, J.; Lanni, F.; Leite, M.; Lissauer, D.; Ma, H.; Makowiecki, D.; Radeka, V.; Rahm, D.; Rajagopalan, S.; Rescia, S.; Stumer, I.; Takai, H.; Yip, K.; Benchekroun, D.; Driouichi, C.; Hoummada, A.; Hakimi, M.; Stroynowski, R.; Ye, J.; Beck Hansen, J.; Belymam, A.; Bremer, J.; Chevalley, J. L.; Fassnacht, P.; Gianotti, F.; Hervas, L.; Marin, C. P.; Pailler, P.; Schilly, P.; Seidl, W.; Vossebeld, J.; Vuillemin, V.; Clark, A.; Efthymiopoulos, I.; Moneta, L.; Belhorma, B.; Collot, J.; de Saintignon, P.; Dzahini, D.; Ferrari, A.; Gallin-Martel, M. L.; Hostachy, J. Y.; Martin, P.; Muraz, J. F.; Ohlsson-Malek, F.; Saboumazrag, S.; Ban, J.; Cartiglia, N.; Cunitz, H.; Dodd, J.; Gara, A.; Leltchouk, M.; Negroni, S.; Parsons, J. A.; Seman, M.; Simion, S.; Sippach, W.; Willis, W.; Barreiro, F.; Garcia, G.; Labarga, L.; Rodier, S.; Del Peso, J.; Alexa, C.; Barrillon, P.; Benchouk, C.; Chekhtman, A.; Dinkespiler, B.; Djama, F.; Duval, P. Y.; Henry-Couannier, F.; Hinz, L.; Jevaud, M.; Karst, P.; Le van Suu, A.; Martin, L.; Martin, O.; Mirea, A.; Monnier, E.; Nagy, E.; Nicod, D.; Olivier, C.; Pralavorio, P.; Repetti, B.; Raymond, M.; Sauvage, D.; Tisserant, S.; Toth, J.; Wielers, M.; Battistoni, G.; Bonivento, W.; Carminati, L.; Cavalli, D.; Costa, G.; Delmastro, M.; Fanti, M.; Mandelli, L.; Mazzanti, M.; Perini, L.; Resconi, S.; Tartarelli, G. F.; Aulchenko, V.; Kazanin, V.; Kolachev, G.; Malyshev, V.; Maslennikov, A.; Pospelov, G.; Snopkov, R.; Shousharo, A.; Talyshev, A.; Tikhonov, Yu.; Augé, E.; Bourdarios, C.; Breton, D.; Cros, P.; de La Taille, C.; Falleau, I.; Fournier, D.; Guilhem, G.; Hassani, S.; Jacquier, Y.; Kordas, K.; Macé, G.; Merkel, B.; Noppe, J. M.; Parrour, G.; Pétroff, P.; Puzo, P.; Richer, J. P.; Rousseau, D.; Seguin-Moreau, N.; Serin, L.; Tocut, V.; Veillet, J. J.; Zerwas, D.; Astesan, F.; Bertoli, W.; Camard, A.; Canton, B.; Fichet, S.; Hubaut, F.; Imbault, D.; Lacour, D.; Laforge, B.; Le Dortz, O.; Martin, D.; Nikolic-Audit, I.; Orsini, F.; Rossel, F.; Schwemling, P.; Cleland, W.; McDonald, J.; Abouelouafa, E. M.; Ben Mansour, A.; Cherkaoui, R.; El Mouahhidi, Y.; Ghazlane, H.; Idrissi, A.; Belorgey, J.; Bernard, R.; Chalifour, M.; Le Coroller, A.; Ernwein, J.; Mansoulié, B.; Renardy, J. F.; Schwindling, J.; Taguet, J.-P.; Teiger, J.; Clément, C.; Lund-Jensen, B.; Lundqvist, J.; Megner, L.; Pearce, M.; Rydstrom, S.; Egdemir, J.; Engelmann, R.; Hoffman, J.; McCarthy, R.; Rijssenbeek, M.; Steffens, J.; Atlas Electromagnetic Liquid Argon Calorimeter Group

    2003-03-01

    The construction and performance of the barrel pre-series module 0 of the future ATLAS electromagnetic calorimeter at the LHC is described. The signal reconstruction and performance of ATLAS-like electronics has been studied. The signal to noise ratio for muons has been found to be 7.11±0.07. An energy resolution of better than 9.5% GeV1/2/ E (sampling term) has been obtained with electron beams of up to 245 GeV. The uniformity of the response to electrons in an area of Δ η×Δ φ=1.2×0.075 has been measured to be better than 0.8%.

  20. Modeling of gun barrel surface erosion: Historic perspective

    SciTech Connect

    Buckingham, A.C.

    1996-08-01

    Results and interpretations of numerical simulations of some dominant processes influencing gun barrel propellant combustion and flow-induced erosion are presented. Results include modeled influences of erosion reduction techniques such as solid additives, vapor phase chemical modifications, and alteration of surface solid composition through use of thin coatings. Precedents and historical perspective are provided with predictions from traditional interior ballistics compared to computer simulations. Accelerating reactive combustion flow, multiphase and multicomponent transport, flow-to-surface thermal/momentum/phase change/gas-surface chemical exchanges, surface and micro-depth subsurface heating/stress/composition evolution and their roles in inducing surface cracking, spall, ablation, melting, and vaporization are considered. Recognition is given to cyclic effects of previous firing history on material preconditioning. Current perspective and outlook for future are based on results of a US Army-LLNL erosion research program covering 7 y in late 1970s. This is supplemented by more recent research on hypervelocity electromagnetic projectile launchers.

  1. Surround suppression and sparse coding in visual and barrel cortices

    PubMed Central

    Sachdev, Robert N. S.; Krause, Matthew R.; Mazer, James A.

    2012-01-01

    During natural vision the entire retina is stimulated. Likewise, during natural tactile behaviors, spatially extensive regions of the somatosensory surface are co-activated. The large spatial extent of naturalistic stimulation means that surround suppression, a phenomenon whose neural mechanisms remain a matter of debate, must arise during natural behavior. To identify common neural motifs that might instantiate surround suppression across modalities, we review models of surround suppression and compare the evidence supporting the competing ideas that surround suppression has either cortical or sub-cortical origins in visual and barrel cortex. In the visual system there is general agreement lateral inhibitory mechanisms contribute to surround suppression, but little direct experimental evidence that intracortical inhibition plays a major role. Two intracellular recording studies of V1, one using naturalistic stimuli (Haider et al., 2010), the other sinusoidal gratings (Ozeki et al., 2009), sought to identify the causes of reduced activity in V1 with increasing stimulus size, a hallmark of surround suppression. The former attributed this effect to increased inhibition, the latter to largely balanced withdrawal of excitation and inhibition. In rodent primary somatosensory barrel cortex, multi-whisker responses are generally weaker than single whisker responses, suggesting multi-whisker stimulation engages similar surround suppressive mechanisms. The origins of suppression in S1 remain elusive: studies have implicated brainstem lateral/internuclear interactions and both thalamic and cortical inhibition. Although the anatomical organization and instantiation of surround suppression in the visual and somatosensory systems differ, we consider the idea that one common function of surround suppression, in both modalities, is to remove the statistical redundancies associated with natural stimuli by increasing the sparseness or selectivity of sensory responses. PMID:22783169

  2. Neuronal activity in rat barrel cortex underlying texture discrimination.

    PubMed

    von Heimendahl, Moritz; Itskov, Pavel M; Arabzadeh, Ehsan; Diamond, Mathew E

    2007-11-01

    Rats and mice palpate objects with their whiskers to generate tactile sensations. This form of active sensing endows the animals with the capacity for fast and accurate texture discrimination. The present work is aimed at understanding the nature of the underlying cortical signals. We recorded neuronal activity from barrel cortex while rats used their whiskers to discriminate between rough and smooth textures. On whisker contact with either texture, firing rate increased by a factor of two to ten. Average firing rate was significantly higher for rough than for smooth textures, and we therefore propose firing rate as the fundamental coding mechanism. The rat, however, cannot take an average across trials, but must make an immediate decision using the signals generated on each trial. To estimate single-trial signals, we calculated the mutual information between stimulus and firing rate in the time window leading to the rat's observed choice. Activity during the last 75 ms before choice transmitted the most informative signal; in this window, neuronal clusters carried, on average, 0.03 bits of information about the stimulus on trials in which the rat's behavioral response was correct. To understand how cortical activity guides behavior, we examined responses in incorrect trials and found that, in contrast to correct trials, neuronal firing rate was higher for smooth than for rough textures. Analysis of high-speed films suggested that the inappropriate signal on incorrect trials was due, at least in part, to nonoptimal whisker contact. In conclusion, these data suggest that barrel cortex firing rate on each trial leads directly to the animal's judgment of texture.

  3. Neuronal Activity in Rat Barrel Cortex Underlying Texture Discrimination

    PubMed Central

    von Heimendahl, Moritz; Itskov, Pavel M; Arabzadeh, Ehsan; Diamond, Mathew E

    2007-01-01

    Rats and mice palpate objects with their whiskers to generate tactile sensations. This form of active sensing endows the animals with the capacity for fast and accurate texture discrimination. The present work is aimed at understanding the nature of the underlying cortical signals. We recorded neuronal activity from barrel cortex while rats used their whiskers to discriminate between rough and smooth textures. On whisker contact with either texture, firing rate increased by a factor of two to ten. Average firing rate was significantly higher for rough than for smooth textures, and we therefore propose firing rate as the fundamental coding mechanism. The rat, however, cannot take an average across trials, but must make an immediate decision using the signals generated on each trial. To estimate single-trial signals, we calculated the mutual information between stimulus and firing rate in the time window leading to the rat's observed choice. Activity during the last 75 ms before choice transmitted the most informative signal; in this window, neuronal clusters carried, on average, 0.03 bits of information about the stimulus on trials in which the rat's behavioral response was correct. To understand how cortical activity guides behavior, we examined responses in incorrect trials and found that, in contrast to correct trials, neuronal firing rate was higher for smooth than for rough textures. Analysis of high-speed films suggested that the inappropriate signal on incorrect trials was due, at least in part, to nonoptimal whisker contact. In conclusion, these data suggest that barrel cortex firing rate on each trial leads directly to the animal's judgment of texture. PMID:18001152

  4. Phylogenetic Analysis of Mitochondrial Outer Membrane β-Barrel Channels

    PubMed Central

    Wojtkowska, Małgorzata; Jąkalski, Marcin; Pieńkowska, Joanna R.; Stobienia, Olgierd; Karachitos, Andonis; Przytycka, Teresa M.; Weiner, January; Kmita, Hanna; Makałowski, Wojciech

    2012-01-01

    Transport of molecules across mitochondrial outer membrane is pivotal for a proper function of mitochondria. The transport pathways across the membrane are formed by ion channels that participate in metabolite exchange between mitochondria and cytoplasm (voltage-dependent anion-selective channel, VDAC) as well as in import of proteins encoded by nuclear genes (Tom40 and Sam50/Tob55). VDAC, Tom40, and Sam50/Tob55 are present in all eukaryotic organisms, encoded in the nuclear genome, and have β-barrel topology. We have compiled data sets of these protein sequences and studied their phylogenetic relationships with a special focus on the position of Amoebozoa. Additionally, we identified these protein-coding genes in Acanthamoeba castellanii and Dictyostelium discoideum to complement our data set and verify the phylogenetic position of these model organisms. Our analysis show that mitochondrial β-barrel channels from Archaeplastida (plants) and Opisthokonta (animals and fungi) experienced many duplication events that resulted in multiple paralogous isoforms and form well-defined monophyletic clades that match the current model of eukaryotic evolution. However, in representatives of Amoebozoa, Chromalveolata, and Excavata (former Protista), they do not form clearly distinguishable clades, although they locate basally to the plant and algae branches. In most cases, they do not posses paralogs and their sequences appear to have evolved quickly or degenerated. Consequently, the obtained phylogenies of mitochondrial outer membrane β-channels do not entirely reflect the recent eukaryotic classification system involving the six supergroups: Chromalveolata, Excavata, Archaeplastida, Rhizaria, Amoebozoa, and Opisthokonta. PMID:22155732

  5. Assembly of 5.5-Meter Diameter Developmental Barrel Segments for the Ares I Upper Stage

    NASA Technical Reports Server (NTRS)

    Carter, Robert W.

    2011-01-01

    Full scale assembly welding of Ares I Upper Stage 5.5-Meter diameter cryogenic tank barrel segments has been performed at the Marshall Space Flight Center (MSFC). One full-scale developmental article produced under the Ares 1 Upper Stage project is the Manufacturing Demonstration Article (MDA) Barrel. This presentation will focus on the welded assembly of this barrel section, and associated lessons learned. Among the MDA articles planned on the Ares 1 Program, the Barrel was the first to be completed, primarily because the process of manufacture from piece parts (barrel panels) utilized the most mature friction stir process planned for use on the Ares US program: Conventional fixed pin Friction Stir Welding (FSW). This process is in use on other space launch systems, including the Shuttle s External Tank, the Delta IV common booster core, the Delta II, and the Atlas V rockets. The goals for the MDA Barrel development were several fold: 1) to prove out Marshall Space Flight Center s new Vertical Weld Tool for use in manufacture of cylindrical barrel sections, 2) to serve as a first run for weld qualification to a new weld specification, and 3) to provide a full size cylindrical section for downstream use in precision cleaning and Spray-on Foam Insulation development. The progression leading into the welding of the full size barrel included sub scale panel welding, subscale cylinder welding, a full length confidence weld, and finally, the 3 seamed MDA barrel processing. Lessons learned on this MDA program have been carried forward into the production tooling for the Ares 1 US Program, and in the use of the MSFC VWT in processing other large scale hardware, including two 8.4 meter diameter Shuttle External Tank barrel sections that are currently being used in structural analysis to validate shell buckling models.

  6. Level 1 Radiance Scaling and Conditioning Algorithm Theoretical Basis

    NASA Technical Reports Server (NTRS)

    Bruegge, C.; Diner, D.; Korechoff, R.; Lee, M.

    2000-01-01

    The Algorithm Theoretical Basis (ATB) document describes the algorithms used to produce the Multi-angle Imaging SpectroRadiometer (MISR) Level 1B1 Radiometric Product, and certain parameters of the Level 1A Reformatted Annotated Product.

  7. Cassini Plasma Spectrometer Investigation

    NASA Astrophysics Data System (ADS)

    Young, D. T.; Berthelier, J. J.; Blanc, M.; Burch, J. L.; Coates, A. J.; Goldstein, R.; Grande, M.; Hill, T. W.; Johnson, R. E.; Kelha, V.; McComas, D. J.; Sittler, E. C.; Svenes, K. R.; Szegö, K.; Tanskanen, P.; Ahola, K.; Anderson, D.; Bakshi, S.; Baragiola, R. A.; Barraclough, B. L.; Black, R. K.; Bolton, S.; Booker, T.; Bowman, R.; Casey, P.; Crary, F. J.; Delapp, D.; Dirks, G.; Eaker, N.; Funsten, H.; Furman, J. D.; Gosling, J. T.; Hannula, H.; Holmlund, C.; Huomo, H.; Illiano, J. M.; Jensen, P.; Johnson, M. A.; Linder, D. R.; Luntama, T.; Maurice, S.; McCabe, K. P.; Mursula, K.; Narheim, B. T.; Nordholt, J. E.; Preece, A.; Rudzki, J.; Ruitberg, A.; Smith, K.; Szalai, S.; Thomsen, M. F.; Viherkanto, K.; Vilppola, J.; Vollmer, T.; Wahl, T. E.; Wüest, M.; Ylikorpi, T.; Zinsmeyer, C.

    2004-09-01

    The Cassini Plasma Spectrometer (CAPS) will make comprehensive three-dimensional mass-resolved measurements of the full variety of plasma phenomena found in Saturn’s magnetosphere. Our fundamental scientific goals are to understand the nature of saturnian plasmas primarily their sources of ionization, and the means by which they are accelerated, transported, and lost. In so doing the CAPS investigation will contribute to understanding Saturn’s magnetosphere and its complex interactions with Titan, the icy satellites and rings, Saturn’s ionosphere and aurora, and the solar wind. Our design approach meets these goals by emphasizing two complementary types of measurements: high-time resolution velocity distributions of electrons and all major ion species; and lower-time resolution, high-mass resolution spectra of all ion species. The CAPS instrument is made up of three sensors: the Electron Spectrometer (ELS), the Ion Beam Spectrometer (IBS), and the Ion Mass Spectrometer (IMS). The ELS measures the velocity distribution of electrons from 0.6 eV to 28,250 keV, a range that permits coverage of thermal electrons found at Titan and near the ring plane as well as more energetic trapped electrons and auroral particles. The IBS measures ion velocity distributions with very high angular and energy resolution from 1 eV to 49,800 keV. It is specially designed to measure sharply defined ion beams expected in the solar wind at 9.5 AU, highly directional rammed ion fluxes encountered in Titan’s ionosphere, and anticipated field-aligned auroral fluxes. The IMS is designed to measure the composition of hot, diffuse magnetospheric plasmas and low-concentration ion species 1 eV to 50,280 eV with an atomic resolution M/ΔM ˜70 and, for certain molecules, (such asN 2 + and CO+), effective resolution as high as ˜2500. The three sensors are mounted on a motor-driven actuator that rotates the entire instrument over approximately one-half of the sky every 3 min.

  8. Gas Chromatic Mass Spectrometer

    NASA Technical Reports Server (NTRS)

    Wey, Chowen

    1995-01-01

    Gas chromatograph/mass spectrometer (GC/MS) used to measure and identify combustion species present in trace concentration. Advanced extractive diagnostic method measures to parts per billion (PPB), as well as differentiates between different types of hydrocarbons. Applicable for petrochemical, waste incinerator, diesel transporation, and electric utility companies in accurately monitoring types of hydrocarbon emissions generated by fuel combustion, in order to meet stricter environmental requirements. Other potential applications include manufacturing processes requiring precise detection of toxic gaseous chemicals, biomedical applications requiring precise identification of accumulative gaseous species, and gas utility operations requiring high-sensitivity leak detection.

  9. The GRANIT spectrometer

    SciTech Connect

    Baessler, Stefan; Beau, M; Kreuz, Michael; Nesvizhevsky, V.; Kurlov, V; Pignol, G; Protasov, K.; Vezzu, Francis; Voronin, Vladimir

    2011-01-01

    The existence of quantum states of matter in a gravitational field was demonstrated recently in the Institut Laue-Langevin (ILL), Grenoble, in a series of experiments with ultra cold neutrons (UCN). UCN in low quantum states is an excellent probe for fundamental physics, in particular for constraining extra short-range forces; as well as a tool in quantum optics and surface physics. The GRANIT is a follow-up project based on a second-generation spectrometer with ultra-high energy resolution, permanently installed in ILL. It has been constructed in framework of an ANR grant; and will become operational in 2011.

  10. Gas Chromatic Mass Spectrometer

    NASA Technical Reports Server (NTRS)

    Wey, Chowen

    1995-01-01

    Gas chromatograph/mass spectrometer (GC/MS) used to measure and identify combustion species present in trace concentration. Advanced extractive diagnostic method measures to parts per billion (PPB), as well as differentiates between different types of hydrocarbons. Applicable for petrochemical, waste incinerator, diesel transporation, and electric utility companies in accurately monitoring types of hydrocarbon emissions generated by fuel combustion, in order to meet stricter environmental requirements. Other potential applications include manufacturing processes requiring precise detection of toxic gaseous chemicals, biomedical applications requiring precise identification of accumulative gaseous species, and gas utility operations requiring high-sensitivity leak detection.

  11. Astronomical Fourier spectrometer.

    PubMed

    Connes, P; Michel, G

    1975-09-01

    A high resolution near ir Fourier spectrometer with the same general design as previously described laboratory instruments has been built for astronomical observations at a coudé focus. Present spectral range is 0.8-3.5 microm with PbS and Ge detectors and maximum path difference 1 m. The servo system can accommodate various recording modes: stepping or continuous scan, path difference modulation, sky chopping. A real time computer is incorporated into the system, which has been set up at the Hale 500-cm telescope on Mount Palomar. Samples of the results are given.

  12. Modular total absorption spectrometer

    NASA Astrophysics Data System (ADS)

    Karny, M.; Rykaczewski, K. P.; Fijałkowska, A.; Rasco, B. C.; Wolińska-Cichocka, M.; Grzywacz, R. K.; Goetz, K. C.; Miller, D.; Zganjar, E. F.

    2016-11-01

    The design and performance of the Modular Total Absorption Spectrometer built and commissioned at the Oak Ridge National Laboratory is presented. The active volume of the detector is approximately one ton of NaI(Tl), which results in very high full γ energy peak efficiency of 71% at 6 MeV and nearly flat efficiency of around 81.5% for low energy γ-rays between 300 keV and 1 MeV. In addition to the high peak efficiency, the modular construction of the detector permits the use of a γ-coincidence technique in data analysis as well as β-delayed neutron observation.

  13. Resonant ultrasound spectrometer

    DOEpatents

    Migliori, Albert; Visscher, William M.; Fisk, Zachary

    1990-01-01

    An ultrasound resonant spectrometer determines the resonant frequency spectrum of a rectangular parallelepiped sample of a high dissipation material over an expected resonant response frequency range. A sample holder structure grips corners of the sample between piezoelectric drive and receive transducers. Each transducer is mounted on a membrane for only weakly coupling the transducer to the holder structure and operatively contacts a material effective to remove system resonant responses at the transducer from the expected response range. i.e., either a material such as diamond to move the response frequencies above the range or a damping powder to preclude response within the range. A square-law detector amplifier receives the response signal and retransmits the signal on an isolated shield of connecting cabling to remove cabling capacitive effects. The amplifier also provides a substantially frequency independently voltage divider with the receive transducer. The spectrometer is extremely sensitive to enable low amplitude resonance to be detected for use in calculating the elastic constants of the high dissipation sample.

  14. The Athena Raman Spectrometer

    NASA Technical Reports Server (NTRS)

    Wang, Alian; Haskin, Larry A.; Jolliff, Bradley; Wdowiak, Tom; Agresti, David; Lane, Arthur L.

    2000-01-01

    Raman spectroscopy provides a powerful tool for in situ mineralogy, petrology, and detection of water and carbon. The Athena Raman spectrometer is a microbeam instrument intended for close-up analyses of targets (rock or soils) selected by the Athena Pancam and Mini-TES. It will take 100 Raman spectra along a linear traverse of approximately one centimeter (point-counting procedure) in one to four hours during the Mars' night. From these spectra, the following information about the target will extracted: (1) the identities of major, minor, and trace mineral phases, organic species (e.g., PAH or kerogen-like polymers), reduced inorganic carbon, and water-bearing phases; (2) chemical features (e.g. Mg/Fe ratio) of major minerals; and (3) rock textural features (e.g., mineral clusters, amygdular filling and veins). Part of the Athena payload, the miniaturized Raman spectrometer has been under development in a highly interactive collaboration of a science team at Washington University and the University of Alabama at Birmingham, and an engineering team at the Jet Propulsion Laboratory. The development has completed the brassboard stage and has produced the design for the engineering model.

  15. Optical fiber interferometric spectrometer

    NASA Astrophysics Data System (ADS)

    Liu, Yong; Li, Baosheng; Liu, Yan; Zhai, Yufeng; Wang, An

    2006-02-01

    We design an optical fiber spectrometer based on optical fiber Mach-Zehnder interferometer. In optical fiber Fourier transform spectrometer spectra information is obtained by Fourier transform of interferogram, which recording intensity change vs. optical path difference. Optical path difference is generated by stretching one fiber arm which wound around fiber stretch drive by high power supply. Information from detector is linear with time rather than with optical path difference. In order to obtain high accuracy wavenumber, reference beam is used to control the optical path difference. Optical path difference is measured by reference laser interference fringe. Interferogram vs. optical path difference is resampled by Brault algorithm with information from reference beam and test beam. In the same condition, one-sided interferogram has higher resolution than that of two-sided interferogram. For one-sided interferogram, zero path difference position must be determined as accurately as possible, small shift will result in phase error. For practical experiment in laboratory, position shift is inevitable, so phase error correction must be considered. Zero order fringe is determined by curve fitting. Spectrum of light source is obtained from one-sided interferogram by Fourier cosine transform. A spectral resolution of about ~3.1 cm -1 is achieved. In practice, higher resolution is needed. This compact equipment will be used in emission spectra and absorption spectra, especially in infrared region.

  16. The Athena Raman Spectrometer

    NASA Technical Reports Server (NTRS)

    Wang, Alian; Haskin, Larry A.; Jolliff, Bradley; Wdowiak, Tom; Agresti, David; Lane, Arthur L.

    2000-01-01

    Raman spectroscopy provides a powerful tool for in situ mineralogy, petrology, and detection of water and carbon. The Athena Raman spectrometer is a microbeam instrument intended for close-up analyses of targets (rock or soils) selected by the Athena Pancam and Mini-TES. It will take 100 Raman spectra along a linear traverse of approximately one centimeter (point-counting procedure) in one to four hours during the Mars' night. From these spectra, the following information about the target will extracted: (1) the identities of major, minor, and trace mineral phases, organic species (e.g., PAH or kerogen-like polymers), reduced inorganic carbon, and water-bearing phases; (2) chemical features (e.g. Mg/Fe ratio) of major minerals; and (3) rock textural features (e.g., mineral clusters, amygdular filling and veins). Part of the Athena payload, the miniaturized Raman spectrometer has been under development in a highly interactive collaboration of a science team at Washington University and the University of Alabama at Birmingham, and an engineering team at the Jet Propulsion Laboratory. The development has completed the brassboard stage and has produced the design for the engineering model.

  17. Organization of myelin in the mouse somatosensory barrel cortex and the effects of sensory deprivation.

    PubMed

    Barrera, Kyrstle; Chu, Philip; Abramowitz, Jason; Steger, Robert; Ramos, Raddy L; Brumberg, Joshua C

    2013-04-01

    In rodents, the barrel cortex is a specialized area within the somatosensory cortex that processes signals from the mystacial whiskers. We investigated the normal development of myelination in the barrel cortex of mice, as well as the effects of sensory deprivation on this pattern. Deprivation was achieved by trimming the whiskers on one side of the face every other day from birth. In control mice, myelin was not present until postnatal day 14 and did not show prominence until postnatal day 30; adult levels of myelination were reached by the end of the second postnatal month. Unbiased stereology was used to estimate axon density in the interbarrel septal region and barrel walls as well as the barrel centers. Myelin was significantly more concentrated in the interbarrel septa/barrel walls than in the barrel centers in both control and sensory-deprived conditions. Sensory deprivation did not impact the onset of myelination but resulted in a significant decrease in myelinated axons in the barrel region and decreased the amount of myelin ensheathing each axon. Visualization of the oligodendrocyte nuclear marker Olig2 revealed a similar pattern of myelin as seen using histochemistry, but with no significant changes in Olig2+ nuclei following sensory deprivation. Consistent with the anatomical results showing less myelination, local field potentials revealed slower rise times following trimming. Our results suggest that myelination develops relatively late and can be influenced by sensory experience.

  18. Weaker feedforward inhibition accounts for less pronounced thalamocortical response transformation in mouse vs. rat barrels

    PubMed Central

    Kwegyir-Afful, E. E.; Kyriazi, H. T.

    2013-01-01

    Feedforward inhibition is a common motif of thalamocortical circuits. Strong engagement of inhibitory neurons by thalamic inputs enhances response differentials between preferred and nonpreferred stimuli. In rat whisker-barrel cortex, robustly driven inhibitory barrel neurons establish a brief epoch during which synchronous or near-synchronous thalamic firing produces larger responses to preferred stimuli, such as high-velocity deflections of the principal whisker in a preferred direction. Present experiments in mice show that barrel neuron responses to preferred vs. nonpreferred stimuli differ less than in rats. In addition, fast-spike units, thought to be inhibitory barrel neurons, fire less robustly to whisker stimuli in mice than in rats. Analyses of real and simulated data indicate that mouse barrel circuitry integrates thalamic inputs over a broad temporal window, and that, as a consequence, responses of barrel neurons are largely similar to those of thalamic neurons. Results are consistent with weaker feedforward inhibition in mouse barrels. Differences in thalamocortical circuitry between mice and rats may reflect mechanical properties of the whiskers themselves. PMID:23966677

  19. The TIM Barrel Architecture Facilitated the Early Evolution of Protein-Mediated Metabolism.

    PubMed

    Goldman, Aaron David; Beatty, Joshua T; Landweber, Laura F

    2016-01-01

    The triosephosphate isomerase (TIM) barrel protein fold is a structurally repetitive architecture that is present in approximately 10% of all enzymes. It is generally assumed that this ubiquity in modern proteomes reflects an essential historical role in early protein-mediated metabolism. Here, we provide quantitative and comparative analyses to support several hypotheses about the early importance of the TIM barrel architecture. An information theoretical analysis of protein structures supports the hypothesis that the TIM barrel architecture could arise more easily by duplication and recombination compared to other mixed α/β structures. We show that TIM barrel enzymes corresponding to the most taxonomically broad superfamilies also have the broadest range of functions, often aided by metal and nucleotide-derived cofactors that are thought to reflect an earlier stage of metabolic evolution. By comparison to other putatively ancient protein architectures, we find that the functional diversity of TIM barrel proteins cannot be explained simply by their antiquity. Instead, the breadth of TIM barrel functions can be explained, in part, by the incorporation of a broad range of cofactors, a trend that does not appear to be shared by proteins in general. These results support the hypothesis that the simple and functionally general TIM barrel architecture may have arisen early in the evolution of protein biosynthesis and provided an ideal scaffold to facilitate the metabolic transition from ribozymes, peptides, and geochemical catalysts to modern protein enzymes.

  20. Mitochondria can recognize and assemble fragments of a β-barrel structure

    PubMed Central

    Müller, Jonas E.N.; Papic, Drazen; Ulrich, Thomas; Grin, Iwan; Schütz, Monika; Oberhettinger, Philipp; Tommassen, Jan; Linke, Dirk; Dimmer, Kai S.; Autenrieth, Ingo B.; Rapaport, Doron

    2011-01-01

    β-barrel proteins are found in the outer membranes of eukaryotic organelles of endosymbiotic origin as well as in the outer membrane of Gram-negative bacteria. Precursors of mitochondrial β-barrel proteins are synthesized in the cytosol and have to be targeted to the organelle. Currently, the signal that assures their specific targeting to mitochondria is poorly defined. To characterize the structural features needed for specific mitochondrial targeting and to test whether a full β-barrel structure is required, we expressed in yeast cells the β-barrel domain of the trimeric autotransporter Yersinia adhesin A (YadA). Trimeric autotransporters are found only in prokaryotes, where they are anchored to the outer membrane by a single 12-stranded β-barrel structure to which each monomer is contributing four β-strands. Importantly, we found that YadA is solely localized to the mitochondrial outer membrane, where it exists in a native trimeric conformation. These findings demonstrate that, rather than a linear sequence or a complete β-barrel structure, four β-strands are sufficient for the mitochondria to recognize and assemble a β-barrel protein. Remarkably, the evolutionary origin of mitochondria from bacteria enables them to import and assemble even proteins belonging to a class that is absent in eukaryotes. PMID:21460184

  1. Structural insight into the biogenesis of β-barrel membrane proteins.

    PubMed

    Noinaj, Nicholas; Kuszak, Adam J; Gumbart, James C; Lukacik, Petra; Chang, Hoshing; Easley, Nicole C; Lithgow, Trevor; Buchanan, Susan K

    2013-09-19

    β-barrel membrane proteins are essential for nutrient import, signalling, motility and survival. In Gram-negative bacteria, the β-barrel assembly machinery (BAM) complex is responsible for the biogenesis of β-barrel membrane proteins, with homologous complexes found in mitochondria and chloroplasts. Here we describe the structure of BamA, the central and essential component of the BAM complex, from two species of bacteria: Neisseria gonorrhoeae and Haemophilus ducreyi. BamA consists of a large periplasmic domain attached to a 16-strand transmembrane β-barrel domain. Three structural features shed light on the mechanism by which BamA catalyses β-barrel assembly. First, the interior cavity is accessible in one BamA structure and conformationally closed in the other. Second, an exterior rim of the β-barrel has a distinctly narrowed hydrophobic surface, locally destabilizing the outer membrane. And third, the β-barrel can undergo lateral opening, suggesting a route from the interior cavity in BamA into the outer membrane.

  2. Spatial heterodyne spectrometer for FLEX

    NASA Astrophysics Data System (ADS)

    Scott, Alan; Zheng, Sheng-Hai; Brown, Stephen; Bell, Andrew

    2007-10-01

    A spatial heterodyne spectrometer (SHS) has significant advantages for high spectral resolution imaging over narrow pre-selected bands compared to traditional solutions. Given comparable optical étendue at R~6500, a field-widened SHS will have a throughput-resolution product ~170 x larger than an air-spaced etalon spectrometer, and ~1000 x larger than a standard grating spectrometer. The monolithic glass Michelson design and lack of moving parts allows maximum stability of spectral calibration over the mission life. For these reasons, SHS offers considerable advantages for the core spectrometer instrument in the European Space Agency's (ESA) Fluorescence Explorer (FLEX) mission.

  3. Particle Spectrometers for FRIB

    NASA Astrophysics Data System (ADS)

    Amthor, A. M.

    2014-09-01

    FRIB promises to dramatically expand the variety of nuclear systems available for direct experimental study by providing rates of many rare isotopes orders of magnitude higher than those currently available. A new generation of experimental systems, including new particle spectrometers will be critical to our ability to take full advantage of the scientific opportunities offered by FRIB. The High-Rigidity Spectrometer (HRS) will allow for experiments with the most neutron-rich and short-lived isotopes produced by in-flight fragmentation at FRIB. The bending capability of the HRS (8 Tm) matches to the rigidity for which rare isotopes are produced at the highest intensity in the FRIB fragment separator. The experimental program will be focused on nuclear structure and astrophysics, and allow for the use of other cutting-edge detection systems for gamma, neutron, and charged-particle detection. Stopped and reaccelerated beam studies will be an important compliment to in-flight techniques at FRIB, providing world-unique, high quality, intense rare isotope beams at low energies up to and beyond the Coulomb barrier--with the completion of ReA12--and serving many of the science goals of the broader facility, from nuclear structure and astrophysics to applications. Two specialized recoil spectrometers are being developed for studies with reaccelerated beams. SECAR, the Separator for Capture Reactions, will be built following ReA3, coupled to a windowless gas jet target, JENSA, and will focus on radiative capture reactions for astrophysics, particularly those needed to improve our understanding of novae and X-ray bursts. A recoil separator following ReA12 is proposed to address a variety of physics cases based on fusion-evaporation, Coulomb excitation, transfer, and deep-inelastic reactions by providing a large angular, momentum and charge state acceptance; a high mass resolving power; and the flexibility to couple to a variety of auxiliary detector systems. Two designs

  4. Heat-Transfer Tests of a Steel Cylinder Barrel with Aluminum Fins

    DTIC Science & Technology

    1939-08-01

    determine the heat-transfer coefficients of the cylinder md the excellence of the bond between the steel barrel and the aluminum fins. com- parison is =de of... EnSino Supercharger. MMA Biormann, Arnold E., and Pinkol, Benjamin: l’innodMetal Oylinders in an Air Stream. 1934. a Jacket. NACA Tests of a R~ots...cylinder barrel trl.th aluminum fins to determine the heat-transfer coefficients’ of the cylinder and the excellence of the bond between the steel barrel

  5. Prenatal alcohol exposure delays the development of the cortical barrel field in neonatal rats.

    PubMed

    Margret, Cecilia P; Li, Cheng X; Chappell, Tyson D; Elberger, Andrea J; Matta, Shannon G; Waters, Robert S

    2006-06-01

    In-utero alcohol exposure produces sensorimotor developmental abnormalities that often persist into adulthood. The rodent cortical barrel field associated with the representation of the body surface was used as our model system to examine the effect of prenatal alcohol exposure (PAE) on early somatosensory cortical development. In this study, pregnant female rats were intragastrically gavaged daily with high doses of alcohol (6 gm/kg body weight) throughout the first 20 days of pregnancy. Blood alcohol levels were measured in the pregnant dams on gestational days 13 (G13) and G20. The ethanol treated group (EtOH) was compared to the normal control chowfed (CF) group, nutritionally matched pairfed (PF) group, and cross-foster (XF) group. Cortical barrel development was examined in pups across all treatment groups from G25, corresponding to postnatal day 2 (P2), to G32 corresponding to P9. The EtOH and control group pups were weighed, anesthetized, and perfused. Brains were removed and weighed with, and without cerebellum and olfactory bulbs, and neocortex was removed and weighed. Cortices were then flattened, sectioned tangentially, and stained with a metabolic marker, cytochrome oxidase (CO) to reveal the barrel field. Progression of barrel development was distinguished into three categories: (a) absent, (b) cloudy barrel-like pattern, and (c) well-formed barrels with intervening septae. The major findings are: (1) PAE delayed barrel field development by one or more days, (2) the barrel field first appeared as a cloudy pattern that gave way on subsequent days to an adult-like pattern with clearly demarcated intervening septal regions, (3) the barrel field developed differentially in a lateral-to-medial gradient in both alcohol and control groups, (4) PAE delayed birth by one or more days in 53% of the pups, (5) regardless of whether pups were born on G23 (normal expected birth date for non-alcohol controls) or as in the case for the alcohol-delayed pups born as

  6. [The composition and characteristics of the spread of the shot products from a gas-barrel weapon].

    PubMed

    Isakov, V D; Babakhanian, R V; Kuznetsov, Iu D; Sigalov, F A

    1998-01-01

    Chemical composition and diffusion of additional factors of a shot from barrel gun supplied with a standard chemical cartridge are studied. Experimental shots from gas pistols of three designs were made. During shots from gas barrel guns the victim is exposed to additional factors characteristic of both fire arms and gas barrel guns, namely, fragments of plastic cartridge container and pads, magnesium particles, and lacquer powder. The characteristics of the short range zone for gas barrel guns correspond to those of short barrel fire arms.

  7. Lead iodide nuclear spectrometers

    SciTech Connect

    Lund, J.C.; Shah, K.S.; Squillante, M.R.; Sinclair, F.

    1988-02-01

    This paper discusses the preparation of radiation detectors from the semiconductor lead iodide, PbI/sub 2/, and evaluates the performance of these devices as x-ray and gamma ray spectrometers. It was found that lead iodide detectors prepared from melt grown crystals exhibited good energy resolution for low energy (<10 keV) x-rays. The energy resolution for higher energy photons was less, consistent with the measured values of the electron and hole mobility-lifetime products. The performance of the PbI/sub 2/ detectors at elevated temperatures was also measured and it was found that the detectors continued to operate well at temperatures over 100/sup 0/C.

  8. Photo ion spectrometer

    DOEpatents

    Gruen, D.M.; Young, C.E.; Pellin, M.J.

    1989-12-26

    A charged particle spectrometer is described for performing ultrasensitive quantitative analysis of selected atomic components removed from a sample. Significant improvements in performing energy and angular refocusing spectroscopy are accomplished by means of a two dimensional structure for generating predetermined electromagnetic field boundary conditions. Both resonance and non-resonance ionization of selected neutral atomic components allow accumulation of increased chemical information. A multiplexed operation between a SIMS mode and a neutral atomic component ionization mode with EARTOF analysis enables comparison of chemical information from secondary ions and neutral atomic components removed from the sample. An electronic system is described for switching high level signals, such as SIMS signals, directly to a transient recorder and through a charge amplifier to the transient recorder for a low level signal pulse counting mode, such as for a neutral atomic component ionization mode. 12 figs.

  9. Photo ion spectrometer

    DOEpatents

    Gruen, Dieter M.; Young, Charles E.; Pellin, Michael J.

    1989-01-01

    A charged particle spectrometer for performing ultrasensitive quantitative analysis of selected atomic components removed from a sample. Significant improvements in performing energy and angular refocusing spectroscopy are accomplished by means of a two dimensional structure for generating predetermined electromagnetic field boundary conditions. Both resonance and non-resonance ionization of selected neutral atomic components allow accumulation of increased chemical information. A multiplexed operation between a SIMS mode and a neutral atomic component ionization mode with EARTOF analysis enables comparison of chemical information from secondary ions and neutral atomic components removed from the sample. An electronic system is described for switching high level signals, such as SIMS signals, directly to a transient recorder and through a charge amplifier to the transient recorder for a low level signal pulse counting mode, such as for a neutral atomic component ionization mode.

  10. Thermoluminescence emission spectrometer.

    PubMed

    Prescott, J R; Fox, P J; Akber, R A; Jensen, H E

    1988-08-15

    A sensitive thermoluminescence (TL) emission spectrometer based on Fourier transform spectroscopy is described. It employs a modified scanning Twyman-Green interferometer with photomultiplier detection in a photon-counting mode. The etendue is 180pi mm(2), and it covers the 350-600-nm wavelength range. The output can be displayed either as a 3-D isometric plot of intensity vs temperature and wavelength, as a contour diagram, or as a conventional TL glow curve of intensity vs temperature. It is sufficiently sensitive to record thermoluminescence spectra of dosimeter phosphors and minerals for thermoluminescence dating at levels corresponding to those found during actual use as radiation monitors or in dating. Examples of actual spectra are given.

  11. Bolometers as particle spectrometers

    NASA Astrophysics Data System (ADS)

    Stroke, H. H.; Artzner, G.; Coron, N.; Dambier, G.; Hansen, P. G.

    1986-02-01

    A spectrometer based on low-temperature calorimetry has been under development since 1983. The present detector, capable of recording individual alpha and beta particles and X-ray photons, is based on a composite diamond-germanium bolometer. The advantage of a composite bolometer is that it separates the absorption and detection functions. Diamond, as an absorber, is of particular advantage because of its low heat capacity and high thermal diffusivity. The goal is a theoretical energy resolution of a few eV at 0.1 K. Initial experiments at 1.3 K and 0.9 K, which give resolutions in the keV range, are still noise-limited. High-resolution applications, such as in X-ray astronomy and nuclear physics (in particular, neutron mass measurements) are foreseen.

  12. Coastal Research Imaging Spectrometer

    NASA Technical Reports Server (NTRS)

    Lucey, Paul G.; Williams, Timothy; Horton, Keith A.

    2002-01-01

    The Coastal Research Imaging Spectrometer (CRIS) is an airborne remote-sensing system designed specifically for research on the physical, chemical, and biological characteristics of coastal waters. The CRIS includes a visible-light hyperspectral imaging subsystem for measuring the color of water, which contains information on the biota, sediment, and nutrient contents of the water. The CRIS also includes an infrared imaging subsystem, which provides information on the temperature of the water. The combination of measurements enables investigation of biological effects of both natural and artificial flows of water from land into the ocean, including diffuse and point-source flows that may contain biological and/or chemical pollutants. Temperature is an important element of such measurements because temperature contrasts can often be used to distinguish among flows from different sources: for example, a sewage outflow could manifest itself in spectral images as a local high-temperature anomaly.

  13. Geometry optimization of a barrel silicon pixelated tracker

    NASA Astrophysics Data System (ADS)

    Liu, Qing-Yuan; Wang, Meng; Winter, Marc

    2017-08-01

    We have studied optimization of the design of a barrel-shaped pixelated tracker for given spatial boundaries. The optimization includes choice of number of layers and layer spacing. Focusing on tracking performance only, momentum resolution is chosen as the figure of merit. The layer spacing is studied based on Gluckstern’s method and a numerical geometry scan of all possible tracker layouts. A formula to give the optimal geometry for curvature measurement is derived in the case of negligible multiple scattering to deal with trajectories of very high momentum particles. The result is validated by a numerical scan method, which could also be implemented with any track fitting algorithm involving material effects, to search for the optimal layer spacing and to determine the total number of layers for the momentum range of interest under the same magnetic field. The geometry optimization of an inner silicon pixel tracker proposed for BESIII is also studied by using a numerical scan and these results are compared with Geant4-based simulations. Supported by National Natural Science Foundation of China (U1232202)

  14. Barrel calorimeters and computer solve boiler circulation problem

    SciTech Connect

    Godbey, J.W.; Ruggles, W.L.

    1997-12-01

    The specific design of water-tube fired boilers and waste-heat steam generators can sometimes actually impede circulation of the steam/water mix essential for proper tube cooling and overall operation. However, proving that and developing corrective measurements can be difficult. This situation can be dealt with using a combination of an antiquated but simple technology--barrel calorimeters--and a computer. The technique shows the effects of boiler load, steam drum water level and modifications to the steam drum primary baffle on tube top-dryness and, indirectly, circulation. The method was applied to up to 20 tubes simultaneously in a chemical plant boiler. The boiler involved was a 300 thousand pound per hour (Mlb/hr) gas-fired unit designed to operate at 335 psig and 600 F. During the first few months of operation, it experienced several incidents of sagging, ductile-swelling and thin-lipped ruptures in the front wall and roof tubes immediately above its burners. These phenomena were also accompanied by scale-related heat blistering of the furnace wall and screen tubes. Were two separate problems being experienced or were these different symptoms of a single problem?

  15. Lens barrel design of the NIRST IR Camera

    NASA Astrophysics Data System (ADS)

    Côté, Patrice; Leclerc, Mélanie; Châteauneuf, François; Marraco, Hugo

    2009-08-01

    The use of uncooled microbolometer detectors for space infrared (IR) imaging application requires high optical throughput, which leads to very fast optical design (~f/1). This directly translates into stringent requirements for components, assembly and alignment. The Institut National d'Optique (INO) in Quebec City, Canada, designed such a system for the NIRST IR Camera. The instrument is part of the Aquarius/SAC-D satellite, a cooperative mission conducted jointly by NASA and the Comisión Nacional de Actividades Espaciales (CONAE) of Argentina. Due to the tight volume and mass allocation, the NIRST camera module is an all refractive design. Since the Camera is made of two lens barrels co-registered to cover the same ground area at different wavelength bands, it also adds coregistration alignment constraints. This paper presents the optomechanical solutions and alignment scheme that enabled the successful design and flight qualification. Trade-off study between thermally induced stress and structural stiffness of the lens RTV bond is discussed. Special attention is given to lens subcell alignment integrity under random vibration encountered during launch. Detailed Finite Element Analysis (FEA) is used to check early design assumptions. Test results of the final vibration campaign are also presented.

  16. Performance of the GlueX Barrel Calorimeter

    NASA Astrophysics Data System (ADS)

    Smith, Elton; Dalton, Mark; McGinley, William; Papandreou, Zisis; GlueX Collaboration

    2015-10-01

    The GlueX experiment at Jefferson Lab will search for exotic hybrid mesons, a new form of hadronic matter that exhibits gluonic degrees of freedom. We have taken data to commission the experiment and report here on the construction and performance of the electromagnetic barrel calorimeter (BCAL). The BCAL is a ``spaghetti calorimeter,'' consisting of layers of corrugated lead sheets, interleaved with planes of 1-mm-diameter, double-clad, scintillating fibers, bonded in the lead grooves using optical epoxy. This detector consists of 48 modules that are readout using 3,840 large-area Multi-Photon Pixel counter (MPPC) arrays. The measured width of the π0 mass peak is approximately 10 MeV, only slightly higher than projections based on prototypes. Systematic studies are underway to understand the contributions to the resolution and improve its performance. This material is based upon work supported by the U.S. Department of Energy, Office of Science, Office of Nuclear Physics under Contract DE-AC05-06OR23177.

  17. Tunable Snapshot Spectrometer Feasibility Study

    DTIC Science & Technology

    2004-09-30

    tunable snapshot imaging spectrometer has been demonstrated. A liquid crystal spatial light modulator (LC SLM) has been integrated into a...integrate a liquid crystal spatial light modulator into a CTIS instrument and characterize its performance as a tunable CTIS disperser, and (2) to...Spectrometer Liquid Crystal Spatial Light Modulator Computer Generated Hologram 15. NUMBER OF PAGES 138

  18. Lunar orbital mass spectrometer experiment

    NASA Technical Reports Server (NTRS)

    Lord, W. P.

    1971-01-01

    The design, development, manufacture, test and calibration of five lunar orbital mass spectrometers with the four associated ground support equipment test sets are discussed. A mass spectrometer was installed in the Apollo 15 and one in the Apollo 16 Scientific Instrument Module within the Service Module. The Apollo 15 mass spectrometer was operated with collection of 38 hours of mass spectra data during lunar orbit and 50 hours of data were collected during transearth coast. The Apollo 16 mass spectrometer was operated with collection of 76 hours of mass spectra data during lunar orbit. However, the Apollo 16 mass spectrometer was ejected into lunar orbit upon malfunction of spacecraft boom system just prior to transearth insection and no transearth coast data was possible.

  19. External barrel temperature of a small bore olympic rifle and shooting precision.

    PubMed

    Gladyszewska, B; Baranowski, P; Mazurek, W; Wozniak, J; Gladyszewski, G

    2013-03-01

    Investigations on changes in a rifle's barrel temperature during shooting in a rhythm typical for practitioners of Olympic shooting sports are presented. Walther KK300 (cal. 5.6 mm), a typical rifle often used in Olympic competitions, R50 RWS ammunition and a high speed thermographic camera were used in the study. Altair version 5 software was used to process thermal images and a stationary wavelet transform was applied to denoise signals for all the studied points. It was found that the temperature of the rifle barrel does not exceed 0.3°C after one shot whereas the total temperature increase does not exceed 5°C after taking 40 shots and does not affect the position of the hitting point on a target. In fact, contrary to popular belief, the so-called "warming shots" are not done for barrel heating but for cleaning of remnants in the barrel.

  20. A radial map of multi-whisker correlation selectivity in the rat barrel cortex

    PubMed Central

    Estebanez, Luc; Bertherat, Julien; Shulz, Daniel E.; Bourdieu, Laurent; Léger, Jean- François

    2016-01-01

    In the barrel cortex, several features of single-whisker stimuli are organized in functional maps. The barrel cortex also encodes spatio-temporal correlation patterns of multi-whisker inputs, but so far the cortical mapping of neurons tuned to such input statistics is unknown. Here we report that layer 2/3 of the rat barrel cortex contains an additional functional map based on neuronal tuning to correlated versus uncorrelated multi-whisker stimuli: neuron responses to uncorrelated multi-whisker stimulation are strongest above barrel centres, whereas neuron responses to correlated and anti-correlated multi-whisker stimulation peak above the barrel–septal borders, forming rings of multi-whisker synchrony-preferring cells. PMID:27869114

  1. Carbon fiber plates production for the CMS tracker outer barrel detector

    SciTech Connect

    Lanfranco, Giobatta; /Fermilab

    2001-03-01

    The production methods together with the achieved flatness and thickness of the composite support structures of the CMS tracker outer barrel (TOB) detector are presented. Possible areas of improvement in the process and in the materials used are also suggested.

  2. Beta 2-adrenergic receptors are colocalized and coregulated with whisker barrels in rat somatosensory cortex

    SciTech Connect

    Vos, P.; Kaufmann, D.; Hand, P.J.; Wolfe, B.B. )

    1990-07-01

    Autoradiography has been used to visualize independently the subtypes of beta-adrenergic receptors in rat somatosensory cortex. Beta 2-adrenergic receptors, but not beta 1-adrenergic receptors colocalize with whisker barrels in this tissue. Thus, each whisker sends a specific multisynaptic pathway to the somatosensory cortex that can be histochemically visualized and only one subtype of beta-adrenergic receptor is specifically associated with this cortical representation. Additionally, neonatal lesion of any or all of the whisker follicles results in loss of the corresponding barrel(s) as shown by histochemical markers. This loss is paralleled by a similar loss in the organization of beta 2-adrenergic receptors in the somatosensory cortex. Other results indicate that these beta 2-adrenergic receptors are not involved in moment-to-moment signal transmission in this pathway and, additionally, are not involved in a gross way in the development of whisker-barrel array.

  3. Long-term Operational Experience with the Barrel CRID at SLD

    SciTech Connect

    Va'Vra, Jaroslav

    1999-05-20

    The Barrel CRID detector has been operating successfully at SLD for the past seven years. It is an important tool for SLD physics analyses. The long-term operational experience with this device is described.

  4. EXTERNAL BARREL TEMPERATURE OF A SMALL BORE OLYMPIC RIFLE AND SHOOTING PRECISION

    PubMed Central

    Gladyszewska, B.; Baranowski, P.; Mazurek, W.; Wozniak, J.

    2013-01-01

    Investigations on changes in a rifle's barrel temperature during shooting in a rhythm typical for practitioners of Olympic shooting sports are presented. Walther KK300 (cal. 5.6 mm), a typical rifle often used in Olympic competitions, R50 RWS ammunition and a high speed thermographic camera were used in the study. Altair version 5 software was used to process thermal images and a stationary wavelet transform was applied to denoise signals for all the studied points. It was found that the temperature of the rifle barrel does not exceed 0.3°C after one shot whereas the total temperature increase does not exceed 5°C after taking 40 shots and does not affect the position of the hitting point on a target. In fact, contrary to popular belief, the so-called “warming shots” are not done for barrel heating but for cleaning of remnants in the barrel. PMID:24744465

  5. Functionally independent columns of rat somatosensory barrel cortex revealed with voltage-sensitive dye imaging.

    PubMed

    Petersen, C C; Sakmann, B

    2001-11-01

    Whisker movement is somatotopically represented in rodent neocortex by electrical activity in clearly defined barrels, which can be visualized in living brain slices. The functional architecture of this part of the cortex can thus be mapped in vitro with respect to its physiological input and compared with its anatomical architecture. The spatial extent of excitation was measured at high temporal resolution by imaging optical signals from voltage-sensitive dye evoked by stimulation of individual barrels in layer 4. The optical signals correlated closely with subthreshold EPSPs recorded simultaneously from excitatory neurons in layer 4 and layer 2/3, respectively. Excitation was initially (<2 msec) limited to the stimulated barrel and subsequently (>3 msec) spread in a columnar manner into layer 2/3 and then subsided in both layers after approximately 50 msec. The lateral extent of the response was limited to the cortical column defined structurally by the barrel in layer 4. Two experimental interventions increased the spread of excitation. First, blocking GABA(A) receptor-mediated synaptic inhibition caused excitation to spread laterally throughout wide regions of layer 2/3 and layer 5 but not into neighboring barrels, suggesting that the local excitatory connections within layer 4 are restricted to single barrels and that inhibitory neurons control spread in supragranular and infragranular layers. Second, NMDA receptor-dependent increase of the spread of excitation was induced by pairing repetitive stimulation of a barrel column with coincident stimulation of layer 2/3 in a neighboring column. Such plasticity in the spatial extent of excitation in a barrel column could underlie changes in cortical map structure induced by alterations of sensory experience.

  6. Yeast Mitochondria as a Model System to Study the Biogenesis of Bacterial β-Barrel Proteins.

    PubMed

    Ulrich, Thomas; Oberhettinger, Philipp; Autenrieth, Ingo B; Rapaport, Doron

    2015-01-01

    Beta-barrel proteins are found in the outer membrane of Gram-negative bacteria, mitochondria, and chloroplasts. The evolutionary conservation in the biogenesis of these proteins allows mitochondria to assemble bacterial β-barrel proteins in their functional form. In this chapter, we describe exemplarily how the capacity of yeast mitochondria to process the trimeric autotransporter YadA can be used to study the role of bacterial periplasmic chaperones in this process.

  7. Cooling Tests of an Air-Cooled Engine Cylinder with Copper Fins on the Barrel

    DTIC Science & Technology

    1942-07-01

    of the piston thermo- couples aro shown in figures 3 and 4. The locations of the cylinder-surface tiernocc-~ples are shown In figure 5. The crankshaft ...the =esult of improvsd fin design shows that the outside barrel temperature may be a poor crite- rion for barrel cooling. ~or example, at 0.7...dimensions in the L . aluminum-muff design Is reetrieted by limits imposed In maohiriing the fins. With aluminum fins, ae with copper fins, the fin

  8. New high-precision drift-tube detectors for the ATLAS muon spectrometer

    NASA Astrophysics Data System (ADS)

    Kroha, H.; Fakhrutdinov, R.; Kozhin, A.

    2017-06-01

    Small-diameter muon drift tube (sMDT) detectors have been developed for upgrades of the ATLAS muon spectrometer. With a tube diameter of 15 mm, they provide an about an order of magnitude higher rate capability than the present ATLAS muon tracking detectors, the MDT chambers with 30 mm tube diameter. The drift-tube design and the construction methods have been optimised for mass production and allow for complex shapes required for maximising the acceptance. A record sense wire positioning accuracy of 5 μm has been achieved with the new design. In the serial production, the wire positioning accuracy is routinely better than 10 μm. 14 new sMDT chambers are already operational in ATLAS, further 16 are under construction for installation in the 2019-2020 LHC shutdown. For the upgrade of the barrel muon spectrometer for High-Luminosity LHC, 96 sMDT chambers will be contructed between 2020 and 2024.

  9. Evolutions of volatile sulfur compounds of Cabernet Sauvignon wines during aging in different oak barrels.

    PubMed

    Ye, Dong-Qing; Zheng, Xiao-Tian; Xu, Xiao-Qing; Wang, Yun-He; Duan, Chang-Qing; Liu, Yan-Lin

    2016-07-01

    The evolution of volatile sulfur compounds (VSCs) in Cabernet Sauvignon wines from seven regions of China during maturation in oak barrels was investigated. The barrels were made of different wood grains (fine and medium) and toasting levels (light and medium). Twelve VSCs were quantified by GC/FPD, with dimethyl sulfide (DMS) and methionol exceeding their sensory thresholds. Most VSCs tended to decline during the aging, while DMS was found to increase. After one year aging, the levels of DMS, 2-methyltetrahy-drothiophen-3-one and sulfur-containing esters were lower in the wines aged in oak barrels than in stainless steel tanks. The wood grain and toasting level of oak barrels significantly influenced the concentration of S-methyl thioacetate and 2-methyltetrahy-drothiophen-3-one. This study reported the evolution of VSCs in wines during oak barrel aging for the first time and evaluated the influence of barrel types, which would provide wine-makers with references in making proposals about wine aging. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Research on vibration characteristics of gun barrel based on contact model

    NASA Astrophysics Data System (ADS)

    Zhao, Yang; Zhou, Qizheng; Yue, Pengfei

    2017-04-01

    In order to study vibration characteristics of the gun barrel under the action of moving projectile, the gun barrel is simplified to cross sectional cantilever beam such as Euler. Considering contact conditions of inertia effect and projectile with the gun barrel, the equation of lateral vibration of the gun barrel is established under the projectile-gun coupling effect; the modal analysis method is used to give the analytic solutions of equation series. The effect of the motion parameters the projectile on the vibration of gun barrel is discussed, and characteristics of vibration of gun barrel are further studied under two conditions of repeating and projectile with mass eccentricity. The research results show that reasonable control of the acceleration of the projectile in the gun bore, and reduction of projectile mass eccentricity can help reduce the muzzle vibration at the gun firing. The research results can provide reference for overall design of the gun, and the modeling and analysis method used in the paper can be promoted for the solution of vibration of other related projects under the moving excitation.

  11. Subbarrel Patterns in Somatosensory Cortical Barrels Can Emerge from Local Dynamic Instabilities

    PubMed Central

    Ermentrout, Bard; Simons, Daniel J.

    2009-01-01

    Complex spatial patterning, common in the brain as well as in other biological systems, can emerge as a result of dynamic interactions that occur locally within developing structures. In the rodent somatosensory cortex, groups of neurons called “barrels” correspond to individual whiskers on the contralateral face. Barrels themselves often contain subbarrels organized into one of a few characteristic patterns. Here we demonstrate that similar patterns can be simulated by means of local growth-promoting and growth-retarding interactions within the circular domains of single barrels. The model correctly predicts that larger barrels contain more spatially complex subbarrel patterns, suggesting that the development of barrels and of the patterns within them may be understood in terms of some relatively simple dynamic processes. We also simulate the full nonlinear equations to demonstrate the predictive value of our linear analysis. Finally, we show that the pattern formation is robust with respect to the geometry of the barrel by simulating patterns on a realistically shaped barrel domain. This work shows how simple pattern forming mechanisms can explain neural wiring both qualitatively and quantitatively even in complex and irregular domains. PMID:19834600

  12. The serotonin reuptake inhibitor citalopram suppresses activity in the neonatal rat barrel cortex in vivo.

    PubMed

    Akhmetshina, Dinara; Zakharov, Andrei; Vinokurova, Daria; Nasretdinov, Azat; Valeeva, Guzel; Khazipov, Roustem

    2016-06-01

    Inhibition of serotonin uptake, which causes an increase in extracellular serotonin levels, disrupts the development of thalamocortical barrel maps in neonatal rodents. Previous in vitro studies have suggested that the disruptive effect of excessive serotonin on barrel map formation involves a depression at thalamocortical synapses. However, the effects of serotonin uptake inhibitors on the early thalamocortical activity patterns in the developing barrel cortex in vivo remain largely unknown. Here, using extracellular recordings of the local field potentials and multiple unit activity (MUA) we explored the effects of the selective serotonin reuptake inhibitor (SSRI) citalopram (10-20mg/kg, intraperitoneally) on sensory evoked activity in the barrel cortex of neonatal (postnatal days P2-5) rats in vivo. We show that administration of citalopram suppresses the amplitude and prolongs the delay of the sensory evoked potentials, reduces the power and frequency of the early gamma oscillations, and suppresses sensory evoked and spontaneous neuronal firing. In the adolescent P21-29 animals, citalopram affected neither sensory evoked nor spontaneous activity in barrel cortex. We suggest that suppression of the early thalamocortical activity patterns contributes to the disruption of the barrel map development caused by SSRIs and other conditions elevating extracellular serotonin levels.

  13. Cortical damping: analysis of thalamocortical response transformations in rodent barrel cortex.

    PubMed

    Pinto, David J; Hartings, Jed A; Brumberg, Joshua C; Simons, Daniel J

    2003-01-01

    In the whisker-barrel system, layer IV excitatory neurons respond preferentially to high-velocity deflections of their principal whisker, and these responses are inhibited by deflections of adjacent whiskers. Thalamic input neurons are amplitude and velocity sensitive and have larger excitatory and weaker inhibitory receptive fields than cortical neurons. Computational models based on known features of barrel circuitry capture these and other differences between thalamic and cortical neuron response properties. The models' responses are highly sensitive to thalamic firing synchrony, a finding subsequently confirmed in real barrels by in vivo experiments. Here, we use dynamic systems analysis to examine how barrel circuitry attains its sensitivity to input timing, and how this sensitivity explains the transformation of receptive fields between thalamus and cortex. We find that strong inhibition renders the net effect of intracortical connections suppressive or damping, distinguishing it from previous amplifying models of cortical microcircuits. In damping circuits, recurrent excitation enhances response tuning not by amplifying responses to preferred inputs, but by enabling them to better withstand strong inhibitory influences. Dense interconnections among barrel neurons result in considerable response homogeneity. Neurons outside the barrel layer respond more heterogeneously, possibly reflecting diverse networks and multiple transformations within the cortical output layers.

  14. Photo ion spectrometer

    DOEpatents

    Gruen, Dieter M.; Young, Charles E.; Pellin, Michael J.

    1989-01-01

    A method and apparatus for extracting for quantitative analysis ions of selected atomic components of a sample. A lens system is configured to provide a slowly diminishing field region for a volume containing the selected atomic components, enabling accurate energy analysis of ions generated in the slowly diminishing field region. The lens system also enables focusing on a sample of a charged particle beam, such as an ion beam, along a path length perpendicular to the sample and extraction of the charged particles along a path length also perpendicular to the sample. Improvement of signal to noise ratio is achieved by laser excitation of ions to selected autoionization states before carrying out quantitative analysis. Accurate energy analysis of energetic charged particles is assured by using a preselected resistive thick film configuration disposed on an insulator substrate for generating predetermined electric field boundary conditions to achieve for analysis the required electric field potential. The spectrometer also is applicable in the fields of SIMS, ISS and electron spectroscopy.

  15. Photo ion spectrometer

    DOEpatents

    Gruen, D.M.; Young, C.E.; Pellin, M.J.

    1989-08-08

    A method and apparatus are described for extracting for quantitative analysis ions of selected atomic components of a sample. A lens system is configured to provide a slowly diminishing field region for a volume containing the selected atomic components, enabling accurate energy analysis of ions generated in the slowly diminishing field region. The lens system also enables focusing on a sample of a charged particle beam, such as an ion beam, along a path length perpendicular to the sample and extraction of the charged particles along a path length also perpendicular to the sample. Improvement of signal to noise ratio is achieved by laser excitation of ions to selected auto-ionization states before carrying out quantitative analysis. Accurate energy analysis of energetic charged particles is assured by using a preselected resistive thick film configuration disposed on an insulator substrate for generating predetermined electric field boundary conditions to achieve for analysis the required electric field potential. The spectrometer also is applicable in the fields of SIMS, ISS and electron spectroscopy. 8 figs.

  16. Aerosol mobility size spectrometer

    DOEpatents

    Wang, Jian; Kulkarni, Pramod

    2007-11-20

    A device for measuring aerosol size distribution within a sample containing aerosol particles. The device generally includes a spectrometer housing defining an interior chamber and a camera for recording aerosol size streams exiting the chamber. The housing includes an inlet for introducing a flow medium into the chamber in a flow direction, an aerosol injection port adjacent the inlet for introducing a charged aerosol sample into the chamber, a separation section for applying an electric field to the aerosol sample across the flow direction and an outlet opposite the inlet. In the separation section, the aerosol sample becomes entrained in the flow medium and the aerosol particles within the aerosol sample are separated by size into a plurality of aerosol flow streams under the influence of the electric field. The camera is disposed adjacent the housing outlet for optically detecting a relative position of at least one aerosol flow stream exiting the outlet and for optically detecting the number of aerosol particles within the at least one aerosol flow stream.

  17. Neutron range spectrometer

    DOEpatents

    Manglos, Stephen H.

    1989-06-06

    A neutron range spectrometer and method for determining the neutron energy spectrum of a neutron emitting source are disclosed. Neutrons from the source are collimnated along a collimation axis and a position sensitive neutron counter is disposed in the path of the collimated neutron beam. The counter determines positions along the collimation axis of interactions between the neutrons in the neutron beam and a neutron-absorbing material in the counter. From the interaction positions, a computer analyzes the data and determines the neutron energy spectrum of the neutron beam. The counter is preferably shielded and a suitable neutron-absorbing material is He-3. The computer solves the following equation in the analysis: ##EQU1## where: N(x).DELTA.x=the number of neutron interactions measured between a position x and x+.DELTA.x, A.sub.i (E.sub.i).DELTA.E.sub.i =the number of incident neutrons with energy between E.sub.i and E.sub.i +.DELTA.E.sub.i, and C=C(E.sub.i)=N .sigma.(E.sub.i) where N=the number density of absorbing atoms in the position sensitive counter means and .sigma. (E.sub.i)=the average cross section of the absorbing interaction between E.sub.i and E.sub.i +.DELTA.E.sub.i.

  18. VEGAS: VErsatile GBT Astronomical Spectrometer

    NASA Astrophysics Data System (ADS)

    Bussa, Srikanth; VEGAS Development Team

    2012-01-01

    The National Science Foundation Advanced Technologies and Instrumentation (NSF-ATI) program is funding a new spectrometer backend for the Green Bank Telescope (GBT). This spectrometer is being built by the CICADA collaboration - collaboration between the National Radio Astronomy Observatory (NRAO) and the Center for Astronomy Signal Processing and Electronics Research (CASPER) at the University of California Berkeley.The backend is named as VErsatile GBT Astronomical Spectrometer (VEGAS) and will replace the capabilities of the existing spectrometers. This backend supports data processing from focal plane array systems. The spectrometer will be capable of processing up to 1.25 GHz bandwidth from 8 dual polarized beams or a bandwidth up to 10 GHz from a dual polarized beam.The spectrometer will be using 8-bit analog to digital converters (ADC), which gives a better dynamic range than existing GBT spectrometers. There will be 8 tunable digital sub-bands within the 1.25 GHz bandwidth, which will enhance the capability of simultaneous observation of multiple spectral transitions. The maximum spectral dump rate to disk will be about 0.5 msec. The vastly enhanced backend capabilities will support several science projects with the GBT. The projects include mapping temperature and density structure of molecular clouds; searches for organic molecules in the interstellar medium; determination of the fundamental constants of our evolving Universe; red-shifted spectral features from galaxies across cosmic time and survey for pulsars in the extreme gravitational environment of the Galactic Center.

  19. Functional diversity of supragranular GABAergic neurons in the barrel cortex

    PubMed Central

    Gentet, Luc J.

    2012-01-01

    Although the neocortex forms a distributed system comprised of several functional areas, its vertical columnar organization is largely conserved across areas and species, suggesting the existence of a canonical neocortical microcircuit. In order to elucidate the principles governing the organization of such a cortical diagram, a detailed understanding of the dynamics binding different types of cortical neurons into a coherent algorithm is essential. Within this complex circuitry, GABAergic interneurons, while forming approximately only 15–20% of all cortical neurons, appear critical in maintaining a dynamic balance between excitation and inhibition. Despite their importance, cortical GABAergic neurons have not been extensively studied in vivo and their precise role in shaping the local microcircuit sensory response still remains to be determined. Their paucity, combined with their molecular, anatomical, and physiological diversity, has made it difficult to even establish a consensual nomenclature. However, recent technological advances in microscopy and mouse genetics have fostered a renewed interest in neocortical interneurons by putting them within “visible” reach of experimenters. The anatomically well-defined whisker-to-barrel pathway of the rodent is particularly amenable to studies attempting to link cortical circuit dynamics to behavior. To each whisker corresponds a discrete cortical unit equivalent to a single column, specialized in the encoding and processing of the sensory information it receives. In this review, we will focus on the functional role that each subtype of supragranular GABAergic neuron embedded within such a single neocortical unit may play in shaping the dynamics of the local circuit during somatosensory integration. PMID:22912602

  20. Flavonoids from barrel medic (Medicago truncatula) aerial parts.

    PubMed

    Kowalska, Iwona; Stochmal, Anna; Kapusta, Ireneusz; Janda, Bogdan; Pizza, Cosimo; Piacente, Sonia; Oleszek, Wieslaw

    2007-04-04

    Twenty-three flavonoids have been identified in the aerial parts of barrel medic, and their structures were established by spectrometric and spectroscopic (ESI-MS/MS and NMR) techniques. Eight of the identified compounds, including apigenin 7-O-beta-D-glucuronopyranosyl-(1-->3)-O-beta-D-glucuronopyranosyl-(1-->2)-O-beta-D-glucuronopyranoside, apigenin 7-O-[2'-O-sinapoyl-beta-D-glucuronopyranosyl-(1-->2)-O-beta-D-glucuronopyranoside], apigenin 7-O-{2-O-feruloyl-[beta-D-glucuronopyranosyl-(1-->3)]-O-beta-D-glucuronopyranosyl-(1-->2)-O-beta-D-glucopyranoside}, chrysoeriol 7-O-[beta-D-glucuronopyranosyl-(1-->2)-O-beta-D-glucuronopyranoside, chrysoeriol 7-O-{2'-O-p-coumaroyl-[beta-D-glucuronopyranosyl-(1-->3)]-O-beta-D-glucuronopyranosyl(1-->2)-O-beta-D-glucuronopyranoside}, tricin 7-O-beta-D-glucuronopyranosyl-4'-O-glucopyranoside, tricin 7-O-[2'-O-feruloyl-beta-D-glucuronopyranosyl-(1-->2)-O-beta-D-glucopyranoside], and tricin 7-O-{2'-O-p-coumaroyl-[beta-D-glucuronopyranosyl-(1-->3)]-O-beta-D-glucuronopyranosyl(1-->2)-O-beta-D-glucuronopyranoside}, have not been reported before in the plant kingdom. Additionally, the presence of two luteolin, three apigenin, one chrysoeriol, and six tricin glycosides, previously identified in alfalfa (Medicago sativa), was confirmed in M. truncatula. Moreover, besides the above flavones, the aerial parts of this species contained three flavonols including rutin, laricitrin 3,7,5'-triglucoside, and laricitrin 3,5'-diglucoside.

  1. Method for calibrating mass spectrometers

    DOEpatents

    Anderson, Gordon A [Benton City, WA; Brands, Michael D [Richland, WA; Bruce, James E [Schwenksville, PA; Pasa-Tolic, Ljiljana [Richland, WA; Smith, Richard D [Richland, WA

    2002-12-24

    A method whereby a mass spectra generated by a mass spectrometer is calibrated by shifting the parameters used by the spectrometer to assign masses to the spectra in a manner which reconciles the signal of ions within the spectra having equal mass but differing charge states, or by reconciling ions having known differences in mass to relative values consistent with those known differences. In this manner, the mass spectrometer is calibrated without the need for standards while allowing the generation of a highly accurate mass spectra by the instrument.

  2. Multiple order common path spectrometer

    NASA Technical Reports Server (NTRS)

    Newbury, Amy B. (Inventor)

    2010-01-01

    The present invention relates to a dispersive spectrometer. The spectrometer allows detection of multiple orders of light on a single focal plane array by splitting the orders spatially using a dichroic assembly. A conventional dispersion mechanism such as a defraction grating disperses the light spectrally. As a result, multiple wavelength orders can be imaged on a single focal plane array of limited spectral extent, doubling (or more) the number of spectral channels as compared to a conventional spectrometer. In addition, this is achieved in a common path device.

  3. Comparison Between Malolactic Fermentation Container and Barrel Toasting Effects on Phenolic, Volatile and Sensory Profile of Red Wines.

    PubMed

    González-Centeno, María Reyes; Chira, Kleopatra; Teissedre, Pierre-Louis

    2017-04-01

    Ellagitannin and anthocyanin profiles, woody volatile composition and sensory properties of wines in which malolactic fermentation (MLF) took place in barrels or stainless steel tanks, have been compared after 12 months of barrel ageing. Three different barrel toastings were evaluated. Barrel-fermented wines generally presented 1.2-fold higher total phenolics, whereas tank-fermented wines exhibited 1.1 and 1.2-fold greater total proanthocyanidin and anthocyanin contents, respectively. Concerning ellagitannin composition, barrel toasting effect seemed to be more important than differences due to MLF-container. Certain woody and fruity volatiles varied significantly (p < 0.05) depending on whether MLF occurred in barrels or tanks. Barrel-fermented wines were preferred in mouth, while olfactory preference depended on barrel toasting. This is the first study that evaluates the impact of oak wood during MLF on ellagitannin composition of wine, as well as the barrel toasting effect on wine attributes during ageing when MLF occurred whether in barrels or tanks.

  4. Agriculture, Levels 1-4. Agriculture & Commercial Horticulture, Levels 1-4. Commercial Horticulture, Levels 1-3. Environmental Conservation, Levels 2-4. National Vocational Qualifications.

    ERIC Educational Resources Information Center

    Business and Technology Education Council, London (England).

    Britain's National Vocational Qualifications (NVQs) are work qualifications that measure what an employee or potential employee can do as well as how much he or she knows and understands about a particular job. Used as written proof of usable workplace skills that can be put to profitable use by an employer, NVQs range from basic Level 1, for…

  5. Upgrades of the ATLAS muon spectrometer with sMDT chambers

    NASA Astrophysics Data System (ADS)

    Ferretti, C.; Kroha, H.; Atlas Muon Collaboration

    2016-07-01

    With half the drift-tube diameter of the Monitored Drift Tube (MDT) chambers of the ATLAS muon spectrometer and otherwise unchanged operating parameters, small-diameter Muon Drift Tube (sMDT) chambers provide an order of magnitude higher rate capability and can be installed in detector regions where MDT chambers do not fit. The chamber assembly time has been reduced by a factor of seven to one working day and the sense wire positioning accuracy improved by a factor of two to better than ten microns. Two sMDT chambers have been installed in ATLAS in 2014 to improve the momentum resolution in the barrel part of the spectrometer. The construction of an additional twelve chambers covering the feet regions of the ATLAS detector has started. It will be followed by the replacement of the MDT chambers at the ends of the barrel inner layer by sMDTs improving the performance at the high expected background rates and providing space for additional RPC trigger chambers.

  6. Coastal Research Imaging Spectrometer

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The Coastal Research Imaging Spectrometer (CRIS) is an airborne remote-sensing system designed specifically for research on the physical, chemical, and biological characteristics of coastal waters. The CRIS includes a visible-light hyperspectral imaging subsystem for measuring the color of water, which contains information on the biota, sediment, and nutrient contents of the water. The CRIS also includes an infrared imaging subsystem, which provides information on the temperature of the water. The combination of measurements enables investigation of biological effects of both natural and artificial flows of water from land into the ocean, including diffuse and point-source flows that may contain biological and/or chemical pollutants. Temperature is an important element of such measurements because temperature contrasts can often be used to distinguish among flows from different sources: for example, a sewage outflow could manifest itself in spectral images as a local high-temperature anomaly.anomaly. Both the visible and infrared subsystems scan in "pushbroom" mode: that is, an aircraft carrying the system moves along a ground track, the system is aimed downward, and image data are acquired in acrosstrack linear arrays of pixels. Both subsystems operate at a frame rate of 30 Hz. The infrared and visible-light optics are adjusted so that both subsystems are aimed at the same moving swath, which has across-track angular width of 15. Data from the infrared and visible imaging subsystems are stored in the same file along with aircraft-position data acquired by a Global Positioning System receiver. The combination of the three sets of data is used to construct infrared and hyperspectral maps of scanned areas shown.

  7. Coastal Research Imaging Spectrometer

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The Coastal Research Imaging Spectrometer (CRIS) is an airborne remote-sensing system designed specifically for research on the physical, chemical, and biological characteristics of coastal waters. The CRIS includes a visible-light hyperspectral imaging subsystem for measuring the color of water, which contains information on the biota, sediment, and nutrient contents of the water. The CRIS also includes an infrared imaging subsystem, which provides information on the temperature of the water. The combination of measurements enables investigation of biological effects of both natural and artificial flows of water from land into the ocean, including diffuse and point-source flows that may contain biological and/or chemical pollutants. Temperature is an important element of such measurements because temperature contrasts can often be used to distinguish among flows from different sources: for example, a sewage outflow could manifest itself in spectral images as a local high-temperature anomaly.anomaly. Both the visible and infrared subsystems scan in "pushbroom" mode: that is, an aircraft carrying the system moves along a ground track, the system is aimed downward, and image data are acquired in acrosstrack linear arrays of pixels. Both subsystems operate at a frame rate of 30 Hz. The infrared and visible-light optics are adjusted so that both subsystems are aimed at the same moving swath, which has across-track angular width of 15. Data from the infrared and visible imaging subsystems are stored in the same file along with aircraft-position data acquired by a Global Positioning System receiver. The combination of the three sets of data is used to construct infrared and hyperspectral maps of scanned areas shown.

  8. Fast-neutron spectrometer developments

    NASA Technical Reports Server (NTRS)

    Moler, R. B.; Zagotta, W. E.; Baker, S. I.

    1973-01-01

    Li6 sandwich-type neutron spectrometer is equipped with proportional counter for particle identification. System uses current-sensitive preamplifiers to minimize pile-up of gamma-ray and particle pulses.

  9. Versatile cluster based photoelectron spectrometer

    SciTech Connect

    Knappenberger, K. L. Jr.; Jones, C. E. Jr.; Sobhy, M. A.; Castleman, A. W. Jr.

    2006-12-15

    A recently constructed cluster based photoelectron spectrometer is described. This instrumentation is unique in that it enables the kinetic energy analysis of electrons ejected from both anions and neutral clusters. This capability permits the investigation of discrete electronic levels in all charge states (anionic, neutral, and cationic). A laser vaporization plasma reactor cluster source affixed with a sublimation cell is employed to produce a variety of metal clusters, and the resulting cluster distributions are analyzed with time-of-flight mass spectrometry. The corresponding electronic structure is analyzed with a 'magnetic bottle' photoelectron spectrometer. Examples of instrument performance operating in both anion photodetachment and neutral multiphoton ionization (MPI) modes are provided. In the case of neutral MPI, the corresponding product distribution is collected with a Wiley-McLaren [Rev. Sci. Instrum. 26, 1150 (1955)] mass spectrometer mounted perpendicular to the magnetic bottle photoelectron spectrometer.

  10. Alpha Magnetic Spectrometer (AMS) Overview

    NASA Image and Video Library

    The Alpha Magnetic Spectrometer (AMS) is flying to the station on STS-134. The AMS experiment is a state-of-the-art particle physics detector being operated by an international team composed of 60 ...

  11. Micromachined Slits for Imaging Spectrometers

    NASA Technical Reports Server (NTRS)

    Wilson, Daniel; Kenny, James; White, Victor

    2008-01-01

    Slits for imaging spectrometers can now be fabricated to a precision much greater than previously attainable. What makes this possible is a micromachining process that involves the use of microlithographic techniques.

  12. The GRAVITY spectrometers: optical qualification

    NASA Astrophysics Data System (ADS)

    Yazici, Senol; Straubmeier, Christian; Wiest, Michael; Wank, Imke; Fischer, Sebastian; Horrobin, Matthew; Eisenhauer, Frank; Perrin, Guy; Perraut, Karine; Brandner, Wolfgang; Amorim, Antonio; Schöller, Markus; Eckart, Andreas

    2014-07-01

    GRAVITY1 is a 2nd generation Very Large Telescope Interferometer (VLTI) operated in the astronomical K-band. In the Beam Combiner Instrument2 (BCI) four Fiber Couplers3 (FC) will feed the light coming from each telescope into two fibers, a reference channel for the fringe tracking spectrometer4 (FT) and a science channel for the science spectrometer4 (SC). The differential Optical Path Difference (dOPD) between the two channels will be corrected using a novel metrology concept.5 The metrology laser will keep control of the dOPD of the two channels. It is injected into the spectrometers and detected at the telescope level. Piezo-actuated fiber stretchers correct the dOPD accordingly. Fiber-fed Integrated Optics6 (IO) combine coherently the light of all six baselines and feed both spectrometers. Assisted by Infrared Wavefront Sensors7 (IWS) at each Unit Telescope (UT) and correcting the path difference between the channels with an accuracy of up to 5 nm, GRAVITY will push the limits of astrometrical accuracy to the order of 10 μas and provide phase-referenced interferometric imaging with a resolution of 4 mas. The University of Cologne developed, constructed and tested both spectrometers of the camera system. Both units are designed for the near infrared (1.95 - 2.45 μm) and are operated in a cryogenic environment. The Fringe Tracker is optimized for highest transmission with fixed spectral resolution (R = 22) realized by a double-prism.8 The Science spectrometer is more diverse and allows to choose from three different spectral resolutions8 (R = [22, 500, 4000]), where the lowest resolution is achieved with a prism and the higher resolutions are realized with grisms. A Wollaston prism in each spectrometer allows for polarimetric splitting of the light. The goal for the spectrometers is to concentrate at least 90% of the ux in 2 × 2 pixel (36 × 36 μm2) for the Science channel and in 1 pixel (24 × 24 μm) in the Fringe Tracking channel. In Section 1, we present

  13. Long-term sensory deprivation selectively rearranges functional inhibitory circuits in mouse barrel cortex.

    PubMed

    Li, Peijun; Rudolph, Uwe; Huntsman, Molly M

    2009-07-21

    Long-term whisker removal alters the balance of excitation and inhibition in rodent barrel cortex, yet little is known about the contributions of individual cells and synapses in this process. We studied synaptic inhibition in four major types of neurons in live tangential slices that isolate layer 4 in the posteromedial barrel subfield. Voltage-clamp recordings of layer 4 neurons reveal that fast decay of synaptic inhibition requires alpha1-containing GABA(A) receptors. After 7 weeks of deprivation, we found that GABA(A)-receptor-mediated inhibitory postsynaptic currents (IPSCs) in the inhibitory low-threshold-spiking (LTS) cell recorded in deprived barrels exhibited faster decay kinetics and larger amplitudes in whisker-deprived barrels than those in nondeprived barrels in age-matched controls. This was not observed in other cell types. Additionally, IPSCs recorded in LTS cells from deprived barrels show a marked increase in zolpidem sensitivity. To determine if the faster IPSC decay in LTS cells from deprived barrels indicates an increase in alpha1 subunit functionality, we deprived alpha1(H101R) mutant mice with zolpidem-insensitive alpha1-containing GABA(A) receptors. In these mice and matched wild-type controls, IPSC decay kinetics in LTS cells were faster after whisker removal; however, the deprivation-induced sensitivity to zolpidem was reduced in alpha1(H101R) mice. These data illustrate a change of synaptic inhibition in LTS cells via an increase in alpha1-subunit-mediated function. Because alpha1 subunits are commonly associated with circuit-specific plasticity in sensory cortex, this switch in LTS cell synaptic inhibition may signal necessary circuit changes required for plastic adjustments in sensory-deprived cortex.

  14. Double-barrel vascularised fibula graft in mandibular reconstruction: a 10-year experience with an algorithm.

    PubMed

    Shen, Yi; Guo, Xue-hua; Sun, Jian; Li, Jun; Shi, Jun; Huang, Wei; Ow, Andrew

    2013-03-01

    This retrospective study aims to report an algorithm to assist surgeons in selecting different modes of the double-barrel vascularised fibula graft for mandibular reconstruction. A total of 45 patients who underwent reconstruction of mandibular defects with different modes of the double-barrel vascularised fibula graft were reviewed. Our algorithm for deciding on any one of the different modes for different mandibular defects is influenced by factors including history of radiotherapy, the length of mandibular body defect and the need to preserve the inferior mandibular border. Post-operative functional outcomes included diet type and speech, and aesthetic results gained at post-operative 2 years. Patients with implant-borne prosthetic teeth underwent assessment of their masticatory function. There were four modes of mandibular reconstruction according to our algorithm, which included double-barrel vascularised fibula graft (n=21), partial double-barrel fibula graft (n=11), condylar prosthesis in combination with partial/double-barrel fibula graft (n=11), and double-barrel fibula onlay graft (n=2). Flap survival in all patients was 97.78%. Good occlusion, bony unions and wound closures were observed in 44 patients. Eleven patients received dental implantation in the transplanted fibula at post-operative 9-18th months. One patient wore removal partial dentures. For 11 patients with implant-borne prosthetic teeth, the average post-operative ipsilateral occlusal force was 41.5±17.7% of the contralateral force. Good functional and aesthetic results were achieved in 38 patients with more than 2 years of follow-up, including regular diet, normal speech and excellent or good appearance, especially for patients with dental rehabilitation. Good aesthetic and functional results can be achieved after dental rehabilitation by following our algorithm when choosing the different modes of double-barrel vascularised fibula graft for mandibular reconstruction. Copyright © 2012

  15. Thalamic adenylyl cyclase 1 is required for barrel formation in the somatosensory cortex.

    PubMed

    Suzuki, A; Lee, L-J; Hayashi, Y; Muglia, L; Itohara, S; Erzurumlu, R S; Iwasato, T

    2015-04-02

    Cyclic AMP signaling is critical for activity-dependent refinement of neuronal circuits. Global disruption of adenylyl cyclase 1 (AC1), the major calcium/calmodulin-stimulated adenylyl cyclase in the brain, impairs formation of whisker-related discrete neural modules (the barrels) in cortical layer 4 in mice. Since AC1 is expressed both in the thalamus and the neocortex, the question of whether pre- or postsynaptic (or both) AC1 plays a role in barrel formation has emerged. Previously, we generated cortex-specific AC1 knockout (Cx-AC1KO) mice and found that these animals develop histologically normal barrels, suggesting a potentially more prominent role for thalamic AC1 in barrel formation. To determine this, we generated three new lines of mice: one in which AC1 is disrupted in nearly half of the thalamic ventrobasal nucleus cells in addition to the cortical excitatory neurons (Cx/pTh-AC1KO mouse), and another in which AC1 is disrupted in the thalamus but not in the cortex or brainstem nuclei of the somatosensory system (Th-AC1KO mouse). Cx/pTh-AC1KO mice show severe deficits in barrel formation. Th-AC1KO mice show even more severe disruption in barrel patterning. In these two lines, single thalamocortical (TC) axon labeling revealed a larger lateral extent of TC axons in layer 4 compared to controls. In the third line, all calcium-stimulated adenylyl cyclases (both AC1 and AC8) are deleted in cortical excitatory neurons. These mice have normal barrels. Taken together, these results indicate that thalamic AC1 plays a major role in patterning and refinement of the mouse TC circuitry.

  16. Public Notification - RTCR Failure To Perform Level 1 Assessment Template

    EPA Pesticide Factsheets

    When a PWS fails to perform a required Level 1 Assessment, it must issue a public notice to inform the consumers of its water of that failure. You can use this template as a guide to prepare that public notice.

  17. The Algorithm Theoretical Basis Document for Level 1A Processing

    NASA Technical Reports Server (NTRS)

    Jester, Peggy L.; Hancock, David W., III

    2012-01-01

    The first process of the Geoscience Laser Altimeter System (GLAS) Science Algorithm Software converts the Level 0 data into the Level 1A Data Products. The Level 1A Data Products are the time ordered instrument data converted from counts to engineering units. This document defines the equations that convert the raw instrument data into engineering units. Required scale factors, bias values, and coefficients are defined in this document. Additionally, required quality assurance and browse products are defined in this document.

  18. Indiana Reading List. [Levels 1, 2, 3, and 4].

    ERIC Educational Resources Information Center

    Indiana State Dept. of Education, Indianapolis.

    This reading list is designed as a companion piece to Indiana's Academic Standards in English/Language Arts and is organized on four levels: Level 1, Grades K-2; Level 2, Grades 3-5; Level 3, Grades 6-8; and Level 4, Grades 9-12. It contains titles and authors for approximately 800 works. The Level 1 Reading List contains these sections: fiction…

  19. Coastal Research Imaging Spectrometer

    NASA Technical Reports Server (NTRS)

    Lucey, Paul G.; Williams, Timothy; Horton, Keith A.

    2004-01-01

    The Coastal Research Imaging Spectrometer (CRIS) is an airborne remote sensing system designed specifically for research on the physical, chemical, and biological characteristics of coastal waters. The CRIS includes a visible-light hyperspectral imaging subsystem for measuring the color of water, which contains information on the biota, sediment, and nutrient contents of the water. The CRIS also includes an infrared imaging subsystem, which provides information on the temperature of the water. The combination of measurements enables investigation of biological effects of both natural and artificial flows of water from land into the ocean, including diffuse and point-source flows that may contain biological and/or chemical pollutants. Temperature is an important element of such measurements because temperature contrasts can often be used to distinguish among flows from different sources: for example, a sewage outflow could manifest itself in spectral images as a local high-temperature anomaly. Both the visible and infrared subsystems scan in pushbroom mode: that is, an aircraft carrying the system moves along a ground track, the system is aimed downward, and image data are acquired in across-track linear arrays of pixels. Both subsystems operate at a frame rate of 30 Hz. The infrared and visible-light optics are adjusted so that both subsystems are aimed at the same moving swath, which has across-track angular width of 15 . Data from the infrared and visible imaging subsystems are stored in the same file along with aircraft- position data acquired by a Global Positioning System receiver. The combination of the three sets of data is used to construct infrared and hyperspectral maps of scanned areas (see figure). The visible subsystem is based on a grating spectrograph and a rapid-readout charge-coupled-device camera. Images of the swatch are acquired in 256 spectral bands at wavelengths from 400 to 800 nm. The infrared subsystem, which is sensitive in a single

  20. Assembly of a Full-Scale External Tank Barrel Section Using Friction Stir Welding

    NASA Technical Reports Server (NTRS)

    Jones, Chip; Adams, Glynn

    1999-01-01

    A full-scale pathfinder barrel section of the External Tank for the National Aeronautics and Space Administration (NASA) Space Transport System (Space Shuttle) has been assembled at Marshall Space Flight Center (MSFC) via a collaborative effort between NASA/MSFC and Lockheed Martin Michoud Space Systems. The barrel section is 27.5 feet in diameter and 15 feet in height. The barrel was assembled using Super-Light-Weight (SLWT), orthogrid, Al-Li 2195 panel sections and a single longeron panel. A vertical weld tool at MSFC was modified to accommodate FSW and used to assemble the barrel. These modifications included the addition of a FSW weld head and new controller hardware and software, the addition of a backing anvil and the replacement of the clamping system with individually actuated clamps. Weld process 4evelopment was initially conducted to optimize the process for the welds required for completing the assembly. The variable thickness welds in the longeron section were conducted via both two-sided welds and with the use of a retractable pin tool. The barrel assembly was completed in October 1998. Details of the vertical weld tool modifications and the assembly process are presented.

  1. Unusual mode of firearm injury from the recoiled rear end of a gun barrel.

    PubMed

    Agrawal, A; Malla, G; Joshi, S; Kumar, A; Koirala, S

    2008-09-01

    Atypical gunshot wounds are caused by a diverse set of parameters relating to weapons and ammunition. We report a previously-unreported and atypical mode of gunshot wound produced by a detached rear end of the barrel of a gun following accidental gun fire, and discuss the difficulties in the management. A 36-year-old man presented to the emergency department with an alleged history of injury on the forehead with the rear end of a gun barrel following accidental gunfire while cleaning the nozzle. Since the time of injury, the patient was in an altered sensorium and had weakness on the right side of the body. There was minimal but continuous bleeding from the wound, with extrusion of brain matter. Skull radiograph showed that the rear end of the barrel had entered the left frontal bone, with associated depressed fracture of the frontal bone. The patient underwent a bicoronal, bifrontal craniotomy with a T-shaped extension towards the barrel to facilitate the reflection of the scalp flap and to avoid any movement of the barrel as it might further injure the brain. Necrotic brain, dura and bone pieces were removed. The patient was doing well at follow-up except for mild residual motor deficits. This case illustrates that while working with limited facilities, particularly in underdeveloped countries, a careful clinical assessment, interpretation of available images and a judicious operative approach can help to save the patient.

  2. Angular tuning and velocity sensitivity in different neuron classes within layer 4 of rat barrel cortex.

    PubMed

    Lee, Soo-Hyun; Simons, Daniel J

    2004-01-01

    Local circuitry within layer IV whisker-related barrels is preferentially sensitive to thalamic population firing synchrony, and neurons respond most vigorously to stimuli, such as high-velocity whisker deflections, that evoke it. Field potential recordings suggest that thalamic barreloid neurons having similar angular preferences fire synchronously. To examine whether angular tuning of cortical neurons might also be affected by thalamic firing synchrony, we characterized responses of layer IV units to whisker deflections that varied in angular direction and velocity. Barrel regular-spike units (RSUs) became more tuned for deflection angle with slower whisker movements. Deflection amplitude had no affect. Barrel fast-spike units (FSUs) were poorly tuned for deflection angle, and their responses remained constant with different deflection velocity. The dependence of angular tuning on deflection velocity among barrel RSUs appears to reflect the same underlying response dynamics that determine their velocity sensitivity and receptive field focus. Unexpectedly, septal RSUs and FSUs are largely similar to their barrel counterparts despite available evidence suggesting that they receive different afferent inputs and are embedded within different local circuits.

  3. RORβ Induces Barrel-like Neuronal Clusters in the Developing Neocortex

    PubMed Central

    Jabaudon, Denis; J. Shnider, Sara; J. Tischfield, David; J. Galazo, Maria

    2012-01-01

    Neurons in layer IV of the rodent whisker somatosensory cortex are tangentially organized in periodic clusters called barrels, each of which is innervated by thalamocortical axons transmitting sensory information from a single principal whisker, together forming a somatotopic map of the whisker pad. Proper thalamocortical innervation is critical for barrel formation during development, but the molecular mechanisms controlling layer IV neuron clustering are unknown. Here, we investigate the role in this mapping of the nuclear orphan receptor RORβ, which is expressed in neurons in layer IV during corticogenesis. We find that RORβ protein expression specifically increases in the whisker barrel cortex during barrel formation and that in vivo overexpression of RORβ is sufficient to induce periodic barrel-like clustering of cortical neurons. Remarkably, this clustering can be induced as early as E18, prior to innervation by thalamocortical afferents and whisker derived-input. At later developmental stages, these ectopic neuronal clusters are specifically innervated by thalamocortical axons, demonstrated by anterograde labeling from the thalamus and by expression of thalamocortical-specific synaptic markers. Together, these data indicate that RORβ expression levels control cytoarchitectural patterning of neocortical neurons during development, a critical process for the topographical mapping of whisker input onto the cortical surface. PMID:21799210

  4. TES Level 1 Algorithms: Interferogram Processing, Geolocation, Radiometric, and Spectral Calibration

    NASA Technical Reports Server (NTRS)

    Worden, Helen; Beer, Reinhard; Bowman, Kevin W.; Fisher, Brendan; Luo, Mingzhao; Rider, David; Sarkissian, Edwin; Tremblay, Denis; Zong, Jia

    2006-01-01

    The Tropospheric Emission Spectrometer (TES) on the Earth Observing System (EOS) Aura satellite measures the infrared radiance emitted by the Earth's surface and atmosphere using Fourier transform spectrometry. The measured interferograms are converted into geolocated, calibrated radiance spectra by the L1 (Level 1) processing, and are the inputs to L2 (Level 2) retrievals of atmospheric parameters, such as vertical profiles of trace gas abundance. We describe the algorithmic components of TES Level 1 processing, giving examples of the intermediate results and diagnostics that are necessary for creating TES L1 products. An assessment of noise-equivalent spectral radiance levels and current systematic errors is provided. As an initial validation of our spectral radiances, TES data are compared to the Atmospheric Infrared Sounder (AIRS) (on EOS Aqua), after accounting for spectral resolution differences by applying the AIRS spectral response function to the TES spectra. For the TES L1 nadir data products currently available, the agreement with AIRS is 1 K or better.

  5. On-chip random spectrometer

    NASA Astrophysics Data System (ADS)

    Redding, B.; Liew, S. F.; Sarma, R.; Cao, H.

    2014-05-01

    Spectrometers are widely used tools in chemical and biological sensing, material analysis, and light source characterization. The development of a high-resolution on-chip spectrometer could enable compact, low-cost spectroscopy for portable sensing as well as increasing lab-on-a-chip functionality. However, the spectral resolution of traditional grating-based spectrometers scales with the optical pathlength, which translates to the linear dimension or footprint of the system, which is limited on-chip. In this work, we utilize multiple scattering in a random photonic structure fabricated on a silicon chip to fold the optical path, making the effective pathlength much longer than the linear dimension of the system and enabling high spectral resolution with a small footprint. Of course, the random spectrometer also requires a different operating paradigm, since different wavelengths are not spatially separated by the random structure, as they would be by a grating. Instead, light transmitted through the random structure produces a wavelengthdependent speckle pattern which can be used as a fingerprint to identify the input spectra after calibration. In practice, these wavelength-dependent speckle patterns are experimentally measured and stored in a transmission matrix, which describes the spectral-to-spatial mapping of the spectrometer. After calibrating the transmission matrix, an arbitrary input spectrum can be reconstructed from its speckle pattern. We achieved sub-nm resolution with 25 nm bandwidth at a wavelength of 1500 nm using a scattering medium with largest dimension of merely 50 μm.

  6. Ultra Compact Imaging Spectrometer (UCIS)

    NASA Astrophysics Data System (ADS)

    Blaney, Diana L.; Green, Robert; Mouroulis, Pantazis; Cable, Morgan; Ehlmann, Bethany; Haag, Justin; Lamborn, Andrew; McKinley, Ian; Rodriguez, Jose; van Gorp, Byron

    2016-10-01

    The Ultra Compact Imaging Spectrometer (UCIS) is a modular visible to short wavelength infrared imaging spectrometer architecture which could be adapted to a variety of mission concepts requiring low mass and low power. Imaging spectroscopy is an established technique to address complex questions of geologic evolution by mapping diagnostic absorption features due to minerals, organics, and volatiles throughout our solar system. At the core of UCIS is an Offner imaging spectrometer using M3 heritage and a miniature pulse tube cryo-cooler developed under the NASA Maturation of Instruments for Solar System Exploration (MatISSE) program to cool the focal plane array. The TRL 6 integrated spectrometer and cryo-cooler provide a basic imaging spectrometer capability that is used with a variety of fore optics to address lunar, mars, and small body science goals. Potential configurations include: remote sensing from small orbiters and flyby spacecraft; in situ panoramic imaging spectroscopy; and in situ micro-spectroscopy. A micro-spectroscopy front end is being developed using MatISSE funding with integration and testing planned this summer.

  7. Resolution-enhanced Mapping Spectrometer

    NASA Technical Reports Server (NTRS)

    Kumer, J. B.; Aubrun, J. N.; Rosenberg, W. J.; Roche, A. E.

    1993-01-01

    A familiar mapping spectrometer implementation utilizes two dimensional detector arrays with spectral dispersion along one direction and spatial along the other. Spectral images are formed by spatially scanning across the scene (i.e., push-broom scanning). For imaging grating and prism spectrometers, the slit is perpendicular to the spatial scan direction. For spectrometers utilizing linearly variable focal-plane-mounted filters the spatial scan direction is perpendicular to the direction of spectral variation. These spectrometers share the common limitation that the number of spectral resolution elements is given by the number of pixels along the spectral (or dispersive) direction. Resolution enhancement by first passing the light input to the spectrometer through a scanned etalon or Michelson is discussed. Thus, while a detector element is scanned through a spatial resolution element of the scene, it is also temporally sampled. The analysis for all the pixels in the dispersive direction is addressed. Several specific examples are discussed. The alternate use of a Michelson for the same enhancement purpose is also discussed. Suitable for weight constrained deep space missions, hardware systems were developed including actuators, sensor, and electronics such that low-resolution etalons with performance required for implementation would weigh less than one pound.

  8. Adaptation to sensory stimulation in the Rat Barrel Cortex

    NASA Astrophysics Data System (ADS)

    Heiss, Jaime

    Sustained stimulation of sensory organs results in adaptation of the neuronal response along the sensory pathway. Whether or not cortical adaptation affects equally excitatory and inhibitory inputs is poorly understood. This question was examined using patch recordings of neurons in the barrel cortex of anesthetized rats while repetitively stimulating the principal whisker. After characterizing the excitation and inhibition evoked either by single or double whisker deflection or by different stimulation strengths, it was found that inhibition, unlike excitation, sums linearly and adapts more, causing the balance between these inputs to shift towards excitation. A comparison of the latency of thalamic firing and evoked synaptic inputs in the cortex strongly suggests that adaptation of inhibition results mostly from depression of inhibitory synapses rather than reduction in the firing of inhibitory cells. A similar change in the balance was reproduced by a simple feedforward model. The differential adaptation of the synaptic inputs that shifts the balance toward excitation may act as a gain mechanism which enhances the subthreshold response during sustained stimulation, despite a reduction in excitation. Natural sensory stimulation rarely arrives in an isolated manner, but in a context of several stimulations, like when a rat sweeps its whisker along a surface with a given texture. It was shown that individual single cells sporadically fail to respond, in a very variable fashion from trial to trial. Whether or not adaptation is correlated among neighboring neurons or is it a private, independent phenomenon was investigated by performing simultaneous recordings. Neighboring neurons presented a highly correlated responsiveness to repetitive stimulation, which strongly varied from trial to trial in a synchronized way. Population averages of a single trial obtained by LFP recordings and VSD imaging differed considerably from the time average but was highly correlated to

  9. HHrep: de novo protein repeat detection and the origin of TIM barrels

    PubMed Central

    Söding, Johannes; Remmert, Michael; Biegert, Andreas

    2006-01-01

    HHrep is a web server for the de novo identification of repeats in protein sequences, which is based on the pairwise comparison of profile hidden Markov models (HMMs). Its main strength is its sensitivity, allowing it to detect highly divergent repeat units in protein sequences whose repeats could as yet only be detected from their structures. Examples include sequences with β-propellor fold, ferredoxin-like fold, double psi barrels or (βα)8 (TIM) barrels. We illustrate this with proteins from four superfamilies of TIM barrels by revealing a clear 4- and 8-fold symmetry, which we detect solely from their sequences. This symmetry might be the trace of an ancient origin through duplication of a βαβα or βα unit. HHrep can be accessed at . PMID:16844977

  10. HHrep: de novo protein repeat detection and the origin of TIM barrels.

    PubMed

    Söding, Johannes; Remmert, Michael; Biegert, Andreas

    2006-07-01

    HHrep is a web server for the de novo identification of repeats in protein sequences, which is based on the pairwise comparison of profile hidden Markov models (HMMs). Its main strength is its sensitivity, allowing it to detect highly divergent repeat units in protein sequences whose repeats could as yet only be detected from their structures. Examples include sequences with beta-propellor fold, ferredoxin-like fold, double psi barrels or (betaalpha)8 (TIM) barrels. We illustrate this with proteins from four superfamilies of TIM barrels by revealing a clear 4- and 8-fold symmetry, which we detect solely from their sequences. This symmetry might be the trace of an ancient origin through duplication of a betaalphabetaalpha or betaalpha unit. HHrep can be accessed at http://hhrep.tuebingen.mpg.de.

  11. [Automatic polishing of dental prostheses. 1. Development of a centrifugal barrel finishing apparatus].

    PubMed

    Tamaki, Y; Miyazaki, T; Aoyama, N; Suzuki, E; Miyaji, T

    1990-09-01

    A centrifugal barrel finishing apparatus with a variable turn table rotational speed (250-1,000 rpm) was newly developed and barrel finishing of Ni-Cr casting plates (10 x 10 x 2 mm) was performed using alumina base chips. When using the sample with a mirror face the amount of polishing and the surface roughness increased and the surface gloss decreased with the increase in rotation speed. A high rotational speed was useful for coarse polishing and low rotational speed was useful for fine polishing. The continuous barrel polishing was trially performed using the sample prepared by the carborundum wheel under variable rotational speed. Automatic polishing to fine polishing could be done using this apparatus.

  12. Beta-Barrel Scaffold of Fluorescent Proteins: Folding, Stability and Role in Chromophore Formation

    PubMed Central

    Stepanenko, Olesya V.; Stepanenko, Olga V.; Kuznetsova, Irina M.; Verkhusha, Vladislav V.; Turoverov, Konstantin K.

    2013-01-01

    This review focuses on the current view of the interaction between the β-barrel scaffold of fluorescent proteins and their unique chromophore located in the internal helix. The chromophore originates from the polypeptide chain and its properties are influenced by the surrounding protein matrix of the β-barrel. On the other hand, it appears that a chromophore tightens the β-barrel scaffold and plays a crucial role in its stability. Furthermore, the presence of a mature chromophore causes hysteresis of protein unfolding and refolding. We survey studies measuring protein unfolding and refolding using traditional methods as well as new approaches, such as mechanical unfolding and reassembly of truncated fluorescent proteins. We also analyze models of fluorescent protein unfolding and refolding obtained through different approaches, and compare the results of protein folding in vitro to co-translational folding of a newly synthesized polypeptide chain. PMID:23351712

  13. Design and fabrication of an advanced, lightweight, high stiffness, railgun barrel concept

    SciTech Connect

    Vrable, D.L.; Rosenwasser, S.N.; Korican, J.A. )

    1991-01-01

    An advanced lightweight and high stiffness railgun barrel design and incorporates several new design features and advanced materials is being developed by SPARTA, Inc. The program is sponsored by the U.S. Army Armament Research, Development, and Engineering Center ARDEC and by the Defense Advanced Research Projects Agency (DARPA). The railgun is 7 m long and has a 90 mm round bore. It is designed to accommodate both solid and plasma armatures. Muzzle energies are expected in the range of 9 to 15 MJ. Analysis and final design has been completed and the barrel and other railgun subassemblies are in the fabrication stage at SPARTA, Inc. in San Diego, California. Initial testing will be conducted at Maxwell Laboratories Green Farm facility in September 1990 and will subsequently be shipped to the ARDEC Railgun Laboratory in October 1990 for full power operation and testing. This paper discusses the design features and fabrication approaches for this high performance, lightweight railgun barrel system.

  14. Lewin estimates 2 billion barrels of US tar sand recoverable at mid $20/bbl

    SciTech Connect

    Not Available

    1986-12-01

    In 1983, Lewin and Associates prepared a report which established that the US tar sands resource amounts to over 60 billion barrels of bitumen in-place. However, no estimate was made of the technically or economically recoverable portion of this resource. More recent work carried out by Lewin for the US Department of Energy presents an appraisal of technically and economically recoverable tar sands. The paper describes the tar sand resource in-place, tar sand recovery models used in the study, engineering cost models, the economics of the steam soak prospect, and the economics of a surface mining prospect. The results of the Lewin study show that 5.7 billion barrels of domestic tar sand are technically recoverable, using cyclic steam injection and surface extractive mining. Of this, 4.9 billion barrels are technically recoverable from surface mining methods, with 0.8 billion recoverable from steam soak applications. 1 figure, 3 tables.

  15. Network mechanisms of spindle-burst oscillations in the neonatal rat barrel cortex in vivo.

    PubMed

    Minlebaev, Marat; Ben-Ari, Yehezkel; Khazipov, Rustem

    2007-01-01

    Early in development, cortical networks generate particular patterns of activity that participate in cortical development. The dominant pattern of electrical activity in the neonatal rat neocortex in vivo is a spatially confined spindle-burst. Here, we studied network mechanisms of generation of spindle-bursts in the barrel cortex of neonatal rats using a superfused cortex preparation in vivo. Both spontaneous and sensory-evoked spindle-bursts were present in the superfused barrel cortex. Pharmacological analysis revealed that spindle-bursts are driven by glutamatergic synapses with a major contribution of AMPA/kainate receptors, but slight participation of NMDA receptors and gap junctions. Although GABAergic synapses contributed minimally to the pacing the rhythm of spindle-burst oscillations, surround GABAergic inhibition appeared to be crucial for their compartmentalization. We propose that local spindle-burst oscillations, driven by glutamatergic synapses and spatially confined by GABAergic synapses, contribute to the development of barrel cortex during the critical period of developmental plasticity.

  16. A novel open-barrel structure of octameric translin reveals a potential RNA entryway.

    PubMed

    Eliahoo, Elad; Marx, Ailie; Manor, Haim; Alian, Akram

    2015-02-27

    The single-stranded DNA (ssDNA)/RNA binding protein translin was suggested to be involved in chromosomal translocations, telomere metabolism, and mRNA transport and translation. Oligonucleotide binding surfaces map within a closed cavity of translin octameric barrels, raising the question as to how DNA/RNA gain access to this inner cavity, particularly given that, to date, none of the barrel structures reported hint to an entryway. Here, we argue against a mechanism by which translin octamers may "dissociate and reassemble" upon RNA binding and report a novel "open"-barrel structure of human translin revealing a feasible DNA/RNA entryway into the cavity. Additionally, we report that translin not only is confined to binding of ssDNA oligonucleotides, or single-stranded extensions of double-stranded DNA (dsDNA), but also can bind single-stranded sequences internally embedded in dsDNA molecules. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Distributed Wireless Monitoring System for Ullage and Temperature in Wine Barrels

    PubMed Central

    Zhang, Wenqi; Skouroumounis, George K.; Monro, Tanya M.; Taylor, Dennis K.

    2015-01-01

    This paper presents a multipurpose and low cost sensor for the simultaneous monitoring of temperature and ullage of wine in barrels in two of the most important stages of winemaking, that being fermentation and maturation. The distributed sensor subsystem is imbedded within the bung of the barrel and runs on battery for a period of at least 12 months and costs around $27 AUD for all parts. In addition, software was designed which allows for the remote transmission and easy visual interpretation of the data for the winemaker. Early warning signals can be sent when the temperature or ullage deviates from a winemakers expectations so remedial action can be taken, such as when topping is required or the movement of the barrels to a cooler cellar location. Such knowledge of a wine’s properties or storage conditions allows for a more precise control of the final wine quality. PMID:26266410

  18. Changes in amine concentrations during aging of red wine in oak barrels.

    PubMed

    Jiménez Moreno, Nerea; Torrea Goñi, Diego; Ancín Azpilicueta, Carmen

    2003-09-10

    This investigation studied the evolution of amines in red wines made with Merlot variety, during aging in American oak barrels (Quercus alba) and in French oak barrels (Quercus sessilis) from the Allier and Nevers regions. From the results obtained it was observed that the evolutions of the amines were similar in all three types of oak woods. Histamine and tyramine were produced at the beginning of the aging process, although they were not accumulated in the wines, probably due to their degradation. Putrescine was the most abundant amine in the wines; its concentration increased to an important extent during aging as it did not undergo degradation. The concentration of cadaverine increased slightly at the first stage of aging and, like putrescine, did not degrade at all. The volatile amines showed slight variations during aging, although in no cases were high accumulations observed in the wines. Dimethylamine and isobutylamine were degraded during storage in the barrels.

  19. Early stages in the biogenesis of eukaryotic β-barrel proteins.

    PubMed

    Jores, Tobias; Rapaport, Doron

    2017-09-01

    The endosymbiotic organelles mitochondria and chloroplasts harbour, similarly to their prokaryotic progenitors, β-barrel proteins in their outer membrane. These proteins are encoded on nuclear DNA, translated on cytosolic ribosomes and imported into their target organelles by a dedicated machinery. Recent studies have provided insights into the import into the organelles and the membrane insertion of these proteins. Although the cytosolic stages of their biogenesis are less well defined, it is speculated that upon their synthesis, chaperones prevent β-barrel proteins from aggregation and keep them in an import-competent conformation. In this Review, we summarize the current knowledge about the biogenesis of β-barrel proteins, focusing on the early stages from the translation on cytosolic ribosomes to the recognition on the surface of the organelle. © 2017 Federation of European Biochemical Societies.

  20. Quench Induced Pressure Rise in the Cooling Pipes of the ATLAS Barrel Toroid Model

    SciTech Connect

    Haug, F.; Bottura, L.; Junker, S.; Broggi, F.

    2004-06-23

    The ATLAS superconducting magnet system consists of a Barrel Toroid, two End-Cap Toroids and a Solenoid. Eight individual racetrack coils will be assembled to form the Barrel Toroid with overall dimensions of 26 m length and 20 m diameter. In order to verify the design concept a 9 m long short version of a single Barrel Toroid coil was built. A test program was conducted at the CERN cryogenic test facility which included the evaluation of the pressure rise in the helium cooling channels during quenches of the coil. A specific experimental set-up with cold pressure transducers and capillaries was installed for online measurement of the pressure signals. In addition a computer model was used to simulate these events. The data obtained are presented.

  1. Level 1 Processing of MODIS Direct Broadcast Data From Terra

    NASA Technical Reports Server (NTRS)

    Lynnes, Christopher; Smith, Peter; Shotland, Larry; El-Ghazawi, Tarek; Zhu, Ming

    2000-01-01

    In February 2000, an effort was begun to adapt the Moderate Resolution Imaging Spectroradiometer (MODIS) Level 1 production software to process direct broadcast data. Three Level 1 algorithms have been adapted and packaged for release: Level 1A converts raw (level 0) data into Hierarchical Data Format (HDF), unpacking packets into scans; Geolocation computes geographic information for the data points in the Level 1A; and the Level 1B computes geolocated, calibrated radiances from the Level 1A and Geolocation products. One useful aspect of adapting the production software is the ability to incorporate enhancements contributed by the MODIS Science Team. We have therefore tried to limit changes to the software. However, in order to process the data immediately on receipt, we have taken advantage of a branch in the geolocation software that reads orbit and altitude information from the packets themselves, rather than external ancillary files used in standard production. We have also verified that the algorithms can be run with smaller time increments (2.5 minutes) than the five-minute increments used in production. To make the code easier to build and run, we have simplified directories and build scripts. Also, dependencies on a commercial numerics library have been replaced by public domain software. A version of the adapted code has been released for Silicon Graphics machines running lrix. Perhaps owing to its origin in production, the software is rather CPU-intensive. Consequently, a port to Linux is underway, followed by a version to run on PC clusters, with an eventual goal of running in near-real-time (i.e., process a ten-minute pass in ten minutes).

  2. Level 1 Processing of MODIS Direct Broadcast Data From Terra

    NASA Technical Reports Server (NTRS)

    Lynnes, Christopher; Smith, Peter; Shotland, Larry; El-Ghazawi, Tarek; Zhu, Ming

    2000-01-01

    In February 2000, an effort was begun to adapt the Moderate Resolution Imaging Spectroradiometer (MODIS) Level 1 production software to process direct broadcast data. Three Level 1 algorithms have been adapted and packaged for release: Level 1A converts raw (level 0) data into Hierarchical Data Format (HDF), unpacking packets into scans; Geolocation computes geographic information for the data points in the Level 1A; and the Level 1B computes geolocated, calibrated radiances from the Level 1A and Geolocation products. One useful aspect of adapting the production software is the ability to incorporate enhancements contributed by the MODIS Science Team. We have therefore tried to limit changes to the software. However, in order to process the data immediately on receipt, we have taken advantage of a branch in the geolocation software that reads orbit and altitude information from the packets themselves, rather than external ancillary files used in standard production. We have also verified that the algorithms can be run with smaller time increments (2.5 minutes) than the five-minute increments used in production. To make the code easier to build and run, we have simplified directories and build scripts. Also, dependencies on a commercial numerics library have been replaced by public domain software. A version of the adapted code has been released for Silicon Graphics machines running lrix. Perhaps owing to its origin in production, the software is rather CPU-intensive. Consequently, a port to Linux is underway, followed by a version to run on PC clusters, with an eventual goal of running in near-real-time (i.e., process a ten-minute pass in ten minutes).

  3. Quantitative/Statistical Approach to Bullet-to-Firearm Identification with Consecutively Manufactured Barrels

    SciTech Connect

    Peter Striupaitis; R.E. Gaensslen

    2005-01-30

    Efforts to use objective image comparison and bullet scanning technologies to distinguish bullets from consecutively manufactured handgun barrels from two manufacturers gave mixed results. The ability of a technology to reliably distinguish between matching and non-matching bullets, where the non-matching bullets were as close in pattern to the matching ones as is probably possible, would provide evidence that the distinctions could be made ''objectively'', and independently of human eyes. That evidence is identical or very close to what seems to be needed to satisfy Daubert standards. It is fair to say that the FTI IBIS image comparison technology correctly distinguished between all the Springfield barrel bullets, and between most but not all of the HiPoint barrel bullets. In the HiPoint cases that were not distinguished 100% of the time, they would he distinguished correctly at least 83% of the time. These results, although obviously limited to the materials used in the comparisons, provide strong evidence that barrel-to-bullet matching is objectively reliable. The results with SciClops were less compelling. The results do not mean that bullet-to-barrel matching is not objectively reliable--rather, they mean that this version of the particular technology could not quite distinguish between these extremely similar yet different bullets as well as the image comparison technology did. In a number of cases, the numerical results made the correct distinctions, although they were close to one another. It is hard to say from this data that this technology differs in its ability to make distinctions between the manufacturers, because the results are very similar with both. The human examiner results were as expected. We did not expect any misidentifications, and there were not any. It would have been preferable to have a higher return rate, and thus more comparisons in the overall sample. As noted, the ''consecutively manufactured barrel exercise'' has been done before

  4. Persistence of biological traces in gun barrels--an approach to an experimental model.

    PubMed

    Courts, Cornelius; Madea, Burkhard; Schyma, Christian

    2012-05-01

    Traces of backspatter in gun barrels after homicidal or suicidal contact shots may be a valuable source of forensic evidence. Yet, a systematic investigation of the persistence and durability of DNA from biological traces in gun barrels is lacking. Our aim was to generate a realistic model to emulate blood and tissue spatters in gun barrels generated by contact gunshots at biological targets and to analyse the persistence and typability of DNA recovered from such stains. Herein, we devise and evaluate three different models for the emulation of backspatter from contact shots: a gelatine-based model with embedded blood bags, a model based on a spongious matrix soaked with blood and covered with a thin plastic membrane and a head model consisting of an acrylic half sphere filled with ballistic gelatine and with blood bags attached to the sphere under a 3-mm silicone layer. The sampling procedure for all three models: a first shot was fired with several types of guns at each model construction and subsequently a second shot was fired at a backstop. Blood samples were collected after each shot by probing the inner surface of the front and rear end of the respective gun barrel with a sterile swab. DNA was then extracted and quantified and up to 20 different short tandem repeat (STR) systems were amplified to generate DNA profiles. Although DNA quantity and STR typing results were heterogenous between the models, all models succeeded in delivering full STR profiles even after more than one shot. We conclude that biological traces in gun barrels are robust and accessible to forensic analysis and that systematic examination of the inside of gun barrels may be advisable for forensic casework.

  5. Mini ion trap mass spectrometer

    DOEpatents

    Dietrich, D.D.; Keville, R.F.

    1995-09-19

    An ion trap is described which operates in the regime between research ion traps which can detect ions with a mass resolution of better than 1:10{sup 9} and commercial mass spectrometers requiring 10{sup 4} ions with resolutions of a few hundred. The power consumption is kept to a minimum by the use of permanent magnets and a novel electron gun design. By Fourier analyzing the ion cyclotron resonance signals induced in the trap electrodes, a complete mass spectra in a single combined structure can be detected. An attribute of the ion trap mass spectrometer is that overall system size is drastically reduced due to combining a unique electron source and mass analyzer/detector in a single device. This enables portable low power mass spectrometers for the detection of environmental pollutants or illicit substances, as well as sensors for on board diagnostics to monitor engine performance or for active feedback in any process involving exhausting waste products. 10 figs.

  6. Mini ion trap mass spectrometer

    DOEpatents

    Dietrich, Daniel D.; Keville, Robert F.

    1995-01-01

    An ion trap which operates in the regime between research ion traps which can detect ions with a mass resolution of better than 1:10.sup.9 and commercial mass spectrometers requiring 10.sup.4 ions with resolutions of a few hundred. The power consumption is kept to a minimum by the use of permanent magnets and a novel electron gun design. By Fourier analyzing the ion cyclotron resonance signals induced in the trap electrodes, a complete mass spectra in a single combined structure can be detected. An attribute of the ion trap mass spectrometer is that overall system size is drastically reduced due to combining a unique electron source and mass analyzer/detector in a single device. This enables portable low power mass spectrometers for the detection of environmental pollutants or illicit substances, as well as sensors for on board diagnostics to monitor engine performance or for active feedback in any process involving exhausting waste products.

  7. Mobile spectrometer measures radar backscatter

    NASA Technical Reports Server (NTRS)

    Gogineni, S.; Moore, R. K.; Onstott, R. G.; Kim, Y. S.; Bushnell, D.

    1984-01-01

    The present article is concerned with a helicopter-borne spectrometer (Heloscat), which has been developed to permit high-quality scattering measurements from a mobile platform at remote sites. The term 'spectrometer' referes to a class of scatterometers. The term 'scatterometer' is employed to denote a specialized radar for measuring scattering coefficients as a function of angle. A spectrometer, on the other hand, is a scatterometer which can measure backscatter at several frequencies. The Heloscat system is discussed, taking into account two antennas, RF hardware, and an externally mounted pendulum for angle encoding. A dual-antenna configuration is used for cross-polarized measurements, while a single-antenna system is used for like-polarized measurements. Attention is also given to oscillator characteristics, efficient data handling, and aspects of calibration.

  8. Weight Reduction Study on the 20MM, M61A1, Vulcan Gun Barrel

    DTIC Science & Technology

    1976-06-01

    breech 20am , M&LAl barrel o o o • OO —o x • —to ^2 cr2- S Effective Bore Boundary Conditions CL h - 3210 BTU/HR - FT« - c 5* » 1350...Minute 18" from breech 20am , MßlAl barrel 3 a 00 —o y ’ o o IT . ’is |LJ§ o. BP z. c Effective Bore Boundary Condltiona h » 23*0...1 Director Joint Military Packaging Training Center ATTN: DRXPT- PT Aberdeen Proving Ground, MD 21005 1 Commander U.S. Army Tropic Test Center

  9. The GRAVITY spectrometers: mechanical design

    NASA Astrophysics Data System (ADS)

    Fischer, Sebastian; Wiest, Michael; Straubmeier, Christian; Yazici, Senol; Araujo-Hauck, Constanza; Eisenhauer, Frank; Perrin, Guy; Brandner, Wolfgang; Perraut, Karine; Amorim, Antonio; Schöller, Markus; Eckart, Andreas

    2010-07-01

    Operating on 6 interferometric baselines, i.e. using all 4 UTs, the 2nd generation VLTI instrument GRAVITY will deliver narrow angle astrometry with 10μas accuracy at the infrared K-band. Within the international GRAVITY consortium, the Cologne institute is responsible for the development and construction of the two spectrometers: one for the science object, and one for the fringe tracking object. Optically two individual components, both spectrometers are two separate units with their own housing and interfaces inside the vacuum vessel of GRAVITY. The general design of the spectrometers, however, is similar. The optical layout is separated into beam collimator (with integrated optics and metrology laser injection) and camera system (with detector, dispersive element, & Wollaston filter wheel). Mechanically, this transfers to two regions which are separated by a solid baffle wall incorporating the blocking filter for the metrology Laser wavelength. The optical subunits are mounted in individual rigid tubes which pay respect to the individual shape, size and thermal expansion of the lenses. For a minimized thermal background, the spectrometers are actively cooled down to an operating temperature of 80K in the ambient temperature environment of the GRAVITY vacuum dewar. The integrated optics beam combiner and the metrology laser injection, which are operated at 200/240K, are mounted thermally isolated to the cold housing of the spectrometers. The optical design has shown that the alignment of the detector is crucial to the performance of the spectrometers. Therefore, in addition to four wheel mechanisms, six cryogenic positioning mechanisms are included in the mechanical design of the detector mount.

  10. The GRAVITY spectrometers: thermal behaviour

    NASA Astrophysics Data System (ADS)

    Wank, Imke; Straubmeier, Christian; Wiest, Michael; Yazici, Senol; Fischer, Sebastian; Eisenhauer, Frank; Perrin, Guy S.; Perraut, Karine; Brandner, Wolfgang; Amorim, Antonio; Schöller, Markus; Eckart, Andreas

    2014-07-01

    GRAVITY is a 2nd generation VLTI Instrument o which operates on 6 interferometric baselines by using all 4 Unit Telescopes. It will deliver narrow angle astrometry with 10μas accuracy at the infrared K-band. At the 1. Physikalische Institut of the University of Cologne, which is part of the international GRAVITY consortium, two spectrometers, one for the sciene object, and one for the fringe tracking object, have been designed, manufactured and tested. These spectrometers are two individual devices, each with own housing and interfaces. For a minimized thermal background, the spectrometers are actively cooled down to an operating temperature of 80K in the ambient temperature environment of the Beam Combiner Instrument (BCI) cryostat. The outer casings are mounted thermal isolated to the base plate by glass fiber reinforced plastic (GRP) stands, copper cooling structures conduct the cold inside the spectrometers where it is routed to components via Cu cooling stripes. The spectrometers are covered with shells made of multi insulation foil. There will be shown and compared 3 cooling installations: setups in the Cologne test dewar, in the BCI dewar and in a mock-up cad model. There are some striking differences between the setup in the 2 different dewars. In the Cologne Test dewar the spectrometers are connected to the coldplate (80K); a Cu cooling structure and the thermal isolating GRP stands are bolted to the coldplate. In the BCI dewer Cu cooling structure is connected to the bottom of the nitrogen tank (80K), the GRP stands are bolted to the base plate (240K). The period of time during the cooldown process will be analyzed.

  11. Double-Barrel Remplissage: An Arthroscopic All-Intra-articular Technique Using the Double-Barrel Knot for Anterior Shoulder Instability.

    PubMed

    Bhatia, Deepak N

    2015-02-01

    The arthroscopic remplissage procedure is an effective addition to a standard anterior repair in traumatic anterior shoulder instability associated with large humeral defects. The double-barrel remplissage is an all-intra-articular technique that uses a double-pulley, sliding, and self-retaining knot mechanism called the double-barrel knot. A 70° arthroscope (posterior portal) is necessary for adequate visualization of the humeral defect and the rotator cuff. Trans-tendon anchors (single or double loaded) are inserted into the superior and inferior aspects of the humeral defect through a cannula that is placed posterior to the infraspinatus. Placement of anchors is facilitated by insertion of a guidewire, as well as an anchor sleeve that is threaded over it. The double-barrel knot is formed using the anchors as a double-pulley system, and the knot is tensioned after the anterior repair is complete. Intra-articular visualization confirms adequate approximation and compression of the infraspinatus tendon and capsule into the defect. Advantages include an increased surface area (footprint) for healing and ease of knotting without the necessity for additional subacromial dissection.

  12. Towed seabed gamma ray spectrometer

    SciTech Connect

    Jones, D.G. )

    1994-08-01

    For more than 50 years, the measurement of radioactivity has been used for onshore geological surveys and in laboratories. The British Geological Survey (BGS) has extended the use of this type of equipment to the marine environment with the development of seabed gamma ray spectrometer systems. The present seabed gamma ray spectrometer, known as the Eel, has been successfully used for sediment and solid rock mapping, mineral exploration, and radioactive pollution studies. The range of applications for the system continues to expand. This paper examines the technological aspects of the Eel and some of the applications for which it has been used.

  13. Mass spectrometers and atomic oxygen

    NASA Technical Reports Server (NTRS)

    Hunton, D. E.; Trzcinski, E.; Cross, J. B.; Spangler, L. H.; Hoffbauer, M. H.; Archuleta, F. H.; Visentine, J. T.

    1987-01-01

    The likely role of atmospheric atomic oxygen in the recession of spacecraft surfaces and in the shuttle glow has revived interest in the accurate measurement of atomic oxygen densities in the upper atmosphere. The Air Force Geophysics Laboratory is supplying a quadrupole mass spectrometer for a materials interactions flight experiment being planned by the Johnson Space Center. The mass spectrometer will measure the flux of oxygen on test materials and will also identify the products of surface reactions. The instrument will be calibrated at a new facility for producing high energy beams of atomic oxygen at the Los Alamos National Laboratory. The plans for these calibration experiments are summarized.

  14. A cometary ion mass spectrometer

    NASA Technical Reports Server (NTRS)

    Shelley, E. G.; Simpson, D. A.

    1984-01-01

    The development of flight suitable analyzer units for that part of the GIOTTO Ion Mass Spectrometer (IMS) experiment designated the High Energy Range Spectrometer (HERS) is discussed. Topics covered include: design of the total ion-optical system for the HERS analyzer; the preparation of the design of analyzing magnet; the evaluation of microchannel plate detectors and associated two-dimensional anode arrays; and the fabrication and evaluation of two flight-suitable units of the complete ion-optical analyzer system including two-dimensional imaging detectors and associated image encoding electronics.

  15. Portable smartphone optical fibre spectrometer

    NASA Astrophysics Data System (ADS)

    Hossain, Md. Arafat; Canning, John; Cook, Kevin; Jamalipour, Abbas

    2015-09-01

    A low cost, optical fibre based spectrometer has been developed on a smartphone platform for field-portable spectral analysis. Light of visible wavelength is collected using a multimode optical fibre and diffracted by a low cost nanoimprinted diffraction grating. A measurement range over 300 nm span (λ = 400 to 700 nm) is obtained using the smartphone CMOS chip. The spectral resolution is Δλ ~ 0.42 nm/screen pixel. A customized Android application processed the spectra on the same platform and shares with other devices. The results compare well with commercially available spectrometer.

  16. A high-throughput neutron spectrometer

    NASA Astrophysics Data System (ADS)

    Stampfl, Anton; Noakes, Terry; Bartsch, Friedl; Bertinshaw, Joel; Veliscek-Carolan, Jessica; Nateghi, Ebrahim; Raeside, Tyler; Yethiraj, Mohana; Danilkin, Sergey; Kearley, Gordon

    2010-03-01

    A cross-disciplinary high-throughput neutron spectrometer is currently under construction at OPAL, ANSTO's open pool light-water research reactor. The spectrometer is based on the design of a Be-filter spectrometer (FANS) that is operating at the National Institute of Standards research reactor in the USA. The ANSTO filter-spectrometer will be switched in and out with another neutron spectrometer, the triple-axis spectrometer, Taipan. Thus two distinct types of neutron spectrometers will be accessible: one specialised to perform phonon dispersion analysis and the other, the filter-spectrometer, designed specifically to measure vibrational density of states. A summary of the design will be given along with a detailed ray-tracing analysis. Some preliminary results will be presented from the spectrometer.

  17. Solution-Focused Group Therapy for Level 1 Substance Abusers

    ERIC Educational Resources Information Center

    Smock, Sara A.; Trepper, Terry S.; Wetchler, Joseph L.; McCollum, Eric E.; Ray, Rose; Pierce, Kent

    2008-01-01

    The present study compared solution-focused group therapy (SFGT) with a traditional problem-focused treatment for level 1 substance abusers. Outcome research on the effectiveness of solution-focused group therapy is minimal, especially in treating substance abusers. In the present study, clients were measured before and after treatment to…

  18. Solution-Focused Group Therapy for Level 1 Substance Abusers

    ERIC Educational Resources Information Center

    Smock, Sara A.; Trepper, Terry S.; Wetchler, Joseph L.; McCollum, Eric E.; Ray, Rose; Pierce, Kent

    2008-01-01

    The present study compared solution-focused group therapy (SFGT) with a traditional problem-focused treatment for level 1 substance abusers. Outcome research on the effectiveness of solution-focused group therapy is minimal, especially in treating substance abusers. In the present study, clients were measured before and after treatment to…

  19. 5. REFIGERATED LOADING DOCK ON LEVEL 1; CHILLING UNIT IS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. REFIGERATED LOADING DOCK ON LEVEL 1; CHILLING UNIT IS VISIBLE AT LEFT; CARCASSES WERE PUSHED ALONG OVERHEAD RAILS BETWEEN RAIL CARS AND COLD STORAGE AREAS - Rath Packing Company, Grease Interceptor Building, Sycamore Street between Elm & Eighteenth Streets, Waterloo, Black Hawk County, IA

  20. Interfacing an aspiration ion mobility spectrometer to a triple quadrupole mass spectrometer

    SciTech Connect

    Adamov, Alexey; Viidanoja, Jyrki; Kaerpaenoja, Esko; Paakkanen, Heikki; Ketola, Raimo A.; Kostiainen, Risto; Sysoev, Alexey; Kotiaho, Tapio

    2007-04-15

    This article presents the combination of an aspiration-type ion mobility spectrometer with a mass spectrometer. The interface between the aspiration ion mobility spectrometer and the mass spectrometer was designed to allow for quick mounting of the aspiration ion mobility spectrometer onto a Sciex API-300 triple quadrupole mass spectrometer. The developed instrumentation is used for gathering fundamental information on aspiration ion mobility spectrometry. Performance of the instrument is demonstrated using 2,6-di-tert-butyl pyridine and dimethyl methylphosphonate.

  1. Interfacing an aspiration ion mobility spectrometer to a triple quadrupole mass spectrometer

    NASA Astrophysics Data System (ADS)

    Adamov, Alexey; Viidanoja, Jyrki; Kärpänoja, Esko; Paakkanen, Heikki; Ketola, Raimo A.; Kostiainen, Risto; Sysoev, Alexey; Kotiaho, Tapio

    2007-04-01

    This article presents the combination of an aspiration-type ion mobility spectrometer with a mass spectrometer. The interface between the aspiration ion mobility spectrometer and the mass spectrometer was designed to allow for quick mounting of the aspiration ion mobility spectrometer onto a Sciex API-300 triple quadrupole mass spectrometer. The developed instrumentation is used for gathering fundamental information on aspiration ion mobility spectrometry. Performance of the instrument is demonstrated using 2,6-di-tert-butyl pyridine and dimethyl methylphosphonate.

  2. Involvement and necessity of the Cpx regulon in the event of aberrant β-barrel outer membrane protein assembly

    PubMed Central

    Gerken, Henri; Leiser, Owen P.; Bennion, Drew; Misra, Rajeev

    2010-01-01

    Summary The Cpx and σE regulons help maintain outer membrane integrity; the Cpx pathway monitors the biogenesis of cell surface structures, such as pili, while the σE pathway monitors the biogenesis of β-barrel outer membrane proteins (OMPs). In this study we revealed the importance of the Cpx regulon in the event of β-barrel OMP mis-assembly, by utilizing mutants expressing either a defective β-barrel OMP assembly machinery (Bam) or assembly defective β-barrel OMPs. Analysis of specific mRNAs showed that ΔcpxR bam double mutants failed to induce degP expression beyond the wild type level, despite activation of the σE pathway. The synthetic conditional lethal phenotype of ΔcpxR in mutant Bam or β-barrel OMP backgrounds was reversed by wild type DegP expressed from a heterologous plasmid promoter. Consistent with the involvement of the Cpx regulon in the event of aberrant β-barrel OMP assembly, the expression of cpxP, the archetypal member of the cpx regulon, was upregulated in defective Bam backgrounds or in cells expressing a single assembly-defective β-barrel OMP species. Together, these results showed that both the Cpx and σE regulons are required to reduce envelope stress caused by aberrant β-barrel OMP assembly, with the Cpx regulon principally contributing by controlling degP expression. PMID:20487295

  3. 27 CFR 25.160 - Tax adjustment for brewers who produce more than 2,000,000 barrels of beer.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... who produce more than 2,000,000 barrels of beer. 25.160 Section 25.160 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.160 Tax adjustment for brewers who produce more than 2,000,000 barrels of beer....

  4. An improved method for constructing and selectively silanizing double-barreled, neutral liquid-carrier, ion-selective microelectrodes

    PubMed Central

    Deveau, Jason S.T.; Grodzinski, Bernard

    2005-01-01

    We describe an improved, efficient and reliable method for the vapour-phase silanization of multi-barreled, ion-selective microelectrodes of which the silanized barrel(s) are to be filled with neutral liquid ion-exchanger (LIX). The technique employs a metal manifold to exclusively and simultaneously deliver dimethyldichlorosilane to only the ion-selective barrels of several multi-barreled microelectrodes. Compared to previously published methods the technique requires fewer procedural steps, less handling of individual microelectrodes, improved reproducibility of silanization of the selected microelectrode barrels and employs standard borosilicate tubing rather than the less-conventional theta-type glass. The electrodes remain stable for up to 3 weeks after the silanization procedure. The efficacy of a double-barreled electrode containing a proton ionophore in the ion-selective barrel is demonstrated in situ in the leaf apoplasm of pea (Pisum) and sunflower (Helianthus). Individual leaves were penetrated to depth of ~150 μm through the abaxial surface. Microelectrode readings remained stable after multiple impalements without the need for a stabilizing PVC matrix. PMID:16136222

  5. Effect of Barrel Material on Critical Current Measurements of High-Jc RRP Nb3Sn Wires

    SciTech Connect

    Ghosh, A.

    2011-08-03

    Nb{sub 3}Sn strands extracted from a 20-strand rectangular Rutherford cable were reacted on either stainless steel or Ti-alloy barrels and the critical current, I{sub c}, in the field range of 8-11.5 T was measured on ITER-type barrels made from Ti-6Al-4V alloy, 304 stainless steel and G-10. Measurements on the 'standard' Ti-alloy barrel using the test procedure employed at BNL are shown to reproduce I{sub c} for extracted strands to {+-}2%. The I{sub c} data for the sample mounted on the 'standard' Ti-alloy are fit to the deviatoric strain scaling model developed for Nb{sub 3}Sn by the University of Twente group using an arbitrary pre-strain. Using the parameters for this fit, the I{sub c} data for the other barrels are fitted by only adjusting the strain. Using this procedure, the strain difference due to the barrel material is determined. Assuming a thermal pre-strain of -0.2% for the sample measured on the Ti-alloy barrel, the use of stainless steel barrel increases the compressive strain by -0.07%, that of G-10 by -0.10%. With the wire soldered to the stainless steel barrel, the strain increases to -0.15%. Details of this study are presented.

  6. 27 CFR 25.160 - Tax adjustment for brewers who produce more than 2,000,000 barrels of beer.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... who produce more than 2,000,000 barrels of beer. 25.160 Section 25.160 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Determination of Tax § 25.160 Tax adjustment for brewers who produce more than 2,000,000 barrels of beer....

  7. 27 CFR 25.160 - Tax adjustment for brewers who produce more than 2,000,000 barrels of beer.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... who produce more than 2,000,000 barrels of beer. 25.160 Section 25.160 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.160 Tax adjustment for brewers who produce more than 2,000,000 barrels of beer....

  8. 27 CFR 25.160 - Tax adjustment for brewers who produce more than 2,000,000 barrels of beer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... who produce more than 2,000,000 barrels of beer. 25.160 Section 25.160 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Tax on Beer Determination of Tax § 25.160 Tax adjustment for brewers who produce more than 2,000,000 barrels of beer....

  9. 27 CFR 25.160 - Tax adjustment for brewers who produce more than 2,000,000 barrels of beer.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... who produce more than 2,000,000 barrels of beer. 25.160 Section 25.160 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Tax on Beer Determination of Tax § 25.160 Tax adjustment for brewers who produce more than 2,000,000 barrels of beer....

  10. Time of flight mass spectrometer

    DOEpatents

    Ulbricht, Jr., William H.

    1984-01-01

    A time-of-flight mass spectrometer is described in which ions are desorbed from a sample by nuclear fission fragments, such that desorption occurs at the surface of the sample impinged upon by the fission fragments. This configuration allows for the sample to be of any thickness, and eliminates the need for complicated sample preparation.

  11. IPNS-I chopper spectrometers

    SciTech Connect

    Price, D.L.; Carpenter, J.M.; Pelizzari, C.A.; Sinha, S.K.; Bresof, I.; Ostrowski, G.E.

    1982-01-01

    We briefly describe the layout and operation of the two chopper experiments at IPNS-I. The recent measurement on solid /sup 4/He by Hilleke et al. provides examples of time-of-flight data from the Low Resolution Chopper Spectrometer.

  12. Alpha proton x ray spectrometer

    NASA Technical Reports Server (NTRS)

    Rieder, Rudi; Waeke, H.; Economou, T.

    1994-01-01

    Mars Pathfinder will carry an alpha-proton x ray spectrometer (APX) for the determination of the elemental chemical composition of Martian rocks and soils. The instrument will measure the concentration of all major and some minor elements, including C, N, and O at levels above typically 1 percent.

  13. MICE Spectrometer Magnet System Progress

    SciTech Connect

    Green, Michael A.; Virostek, Steve P.

    2007-08-27

    The first magnets for the muon ionization cooling experimentwill be the tracker solenoids that form the ends of the MICE coolingchannel. The primary purpose of the tracker solenoids is to provide auniform 4 T field (to better than +-0.3 percent over a volume that is 1meter long and 0.3 meters in diameter) spectrometer magnet field for thescintillating fiber detectors that are used to analyze the muons in thechannel before and after ionization cooling. A secondary purpose for thetracker magnet is the matching of the muon beam between the rest of theMICE cooling channel and the uniform field spectrometer magnet. Thetracker solenoid is powered by three 300 amp power supplies. Additionaltuning of the spectrometer is provided by a pair of 50 amp power suppliesacross the spectrometer magnet end coils. The tracker magnet will becooled using a pair of 4 K pulse tube coolers that each provide 1.5 W ofcooling at 4.2 K. Final design and construction of the tracker solenoidsbegan during the summer of 2006. This report describes the progress madeon the construction of the tracker solenoids.

  14. Airborne spectrometer senses several gases

    NASA Technical Reports Server (NTRS)

    Mc Dowall, J.; Moffat, A. J.

    1970-01-01

    Spectrometer's variable shutter permits observation of a wide range of plume widths. Adjustable grating, counter, and access window enable operator to reset grating's position during flight by resetting the counter to a predetermined number. Quartz correlation mask and spectral-aperture instrument-function filter are mounted in a replaceable precision frame.

  15. Convex Diffraction Grating Imaging Spectrometer

    NASA Technical Reports Server (NTRS)

    Chrisp, Michael P. (Inventor)

    1999-01-01

    A 1:1 Offner mirror system for imaging off-axis objects is modified by replacing a concave spherical primary mirror that is concentric with a convex secondary mirror with two concave spherical mirrors M1 and M2 of the same or different radii positioned with their respective distances d1 and d2 from a concentric convex spherical diffraction grating having its grooves parallel to the entrance slit of the spectrometer which replaces the convex secondary mirror. By adjusting their distances d1 and d2 and their respective angles of reflection alpha and beta, defined as the respective angles between their incident and reflected rays, all aberrations are corrected without the need to increase the spectrometer size for a given entrance slit size to reduce astigmatism, thus allowing the imaging spectrometer volume to be less for a given application than would be possible with conventional imaging spectrometers and still give excellent spatial and spectral imaging of the slit image spectra over the focal plane.

  16. Imaging IR spectrometer, phase 2

    NASA Technical Reports Server (NTRS)

    Gradie, Jonathan; Lewis, Ralph; Lundeen, Thomas; Wang, Shu-I

    1990-01-01

    The development is examined of a prototype multi-channel infrared imaging spectrometer. The design, construction and preliminary performance is described. This instrument is intended for use with JPL Table Mountain telescope as well as the 88 inch UH telescope on Mauna Kea. The instrument is capable of sampling simultaneously the spectral region of 0.9 to 2.6 um at an average spectral resolution of 1 percent using a cooled (77 K) optical bench, a concave holographic grating and a special order sorting filter to allow the acquisition of the full spectral range on a 128 x 128 HgCdTe infrared detector array. The field of view of the spectrometer is 0.5 arcsec/pixel in mapping mode and designed to be 5 arcsec/pixel in spot mode. The innovative optical design has resulted in a small, transportable spectrometer, capable of remote operation. Commercial applications of this spectrometer design include remote sensing from both space and aircraft platforms as well as groundbased astronomical observations.

  17. Mid infrared MEMS FTIR spectrometer

    NASA Astrophysics Data System (ADS)

    Erfan, Mazen; Sabry, Yasser M.; Mortada, Bassem; Sharaf, Khaled; Khalil, Diaa

    2016-03-01

    In this work we report, for the first time to the best of our knowledge, a bulk-micromachined wideband MEMS-based spectrometer covering both the NIR and the MIR ranges and working from 1200 nm to 4800 nm. The core engine of the spectrometer is a scanning Michelson interferometer micro-fabricated using deep reactive ion etching (DRIE) technology. The spectrum is obtained using the Fourier Transform techniques that allows covering a very wide spectral range limited by the detector responsivity. The moving mirror of the interferometer is driven by a relatively large stroke electrostatic comb-drive actuator. Zirconium fluoride (ZrF4) multimode optical fibers are used to connect light between the white light source and the interferometer input, as well as the interferometer output to a PbSe photoconductive detector. The recorded signal-to-noise ratio is 25 dB at the wavelength of 3350 nm. The spectrometer is successfully used in measuring the absorption spectra of methylene chloride, quartz glass and polystyrene film. The presented solution provides a low cost method for producing miniaturized spectrometers in the near-/mid-infrared.

  18. E781 Hyperon Spectrometer Constants

    SciTech Connect

    Joseph T. Lach

    2004-05-04

    This is a discussion of the physical measurements, sizes, distances and magnetic fields of the Hyperon Spectrometer Magnet and its components. Some we get from construction drawings (like the target dimensions) and others from measurements in differing coordinate systems. Included also are the properties of the hyperon productions targets used in E781.

  19. Acoustically-tuned optical spectrometer

    NASA Technical Reports Server (NTRS)

    Sklar, E.

    1981-01-01

    Lens arrangement corrects for aberrations and gives resolution of 0.7 seconds of arc. In spectrometer, light from telescope is relayed by doublet lens to acoustically tuned optical filter. Selected wavelengths are relayed by triplet lens to charge coupled device camera. Intervening cylindrical lens, tilted at 12 degree angle, corrects for astigmatism and coma introduced by two element birefringent crystal in filter.

  20. RF spectrometers for heterodyne receivers

    NASA Technical Reports Server (NTRS)

    Buhl, D.; Mumma, M. J.

    1980-01-01

    Several types of spectrometers developed for radio astronomy receivers which utilize RF filters, multiple oscillators and mixers, digital autocorrelators and acoustic/optic devices are considered. The RF spectrometer developed at GSFC to provide wide bandwidths (greater than 1 GHz) as well as high resolution (5MHz) is described. The 128 channel filter bank is divided into high and low resolution sections. The high resolution section is tunable by providing a second mixer ahead of the filter bank. This is necessary because infrared receivers which use gas lasers as local oscillators are only tunable to specific laser frequencies. To compensate for astronomical Doppler shifts and molecule frequency differences a second local oscillator and mixer is needed. A diagram of the RF section of the filter bank is shown. The RF spectrometer is shown to be the best means of achieving ultra-wide bandwidths for infrared heterodyne receivers. For high resolution with a large number of channels, the acousto/optical spectrometer is the principle instrument, particularly for balloon or space flight applications.

  1. Inventory Control: Multiport Student Spectrometer.

    ERIC Educational Resources Information Center

    Bishop, Carl B.

    1989-01-01

    Described is a spectrometer that can be used simultaneously by seven students to observe a single spectrum emitted by an element or compound in a single light tube against a calibrated screen. Included is a list of materials, directions for assembly, and procedures for use. (CW)

  2. Volatile compounds and sensorial characterisation of red wine aged in cherry, chestnut, false acacia, ash and oak wood barrels.

    PubMed

    Fernández de Simón, B; Martínez, J; Sanz, M; Cadahía, E; Esteruelas, E; Muñoz, A M

    2014-03-15

    The wood-related volatile profile of wines aged in cherry, acacia, ash, chestnut and oak wood barrels was studied by GC-MS, and could be a useful tool to identify the wood specie used. Thus, 2,4-dihydroxybenzaldehyde in wines aged in acacia barrels, and ethyl-2-benzoate in cherry barrels could be used as chemical markers of these wood species, for authenticity purposes. Also, the quantitative differences obtained in the volatile profiles allow a good classification of all wines regarding wood species of barrels, during all aging time, and they contributed with different intensities to aromatic and gustative characteristics of aged wines. Wines aged in oak were the best valuated during all aging time, but the differences were not always significant. The lowest scores were assigned to wines aged in cherry barrels from 6 months of aging, so this wood could be more suitable in short aging times.

  3. Fire testing and infrared thermography of oak barrels filled with distilled spirits (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    de Vries, Jaap

    2017-05-01

    Adequate fire protection of distilled spirits stored in oak barrels requires understanding the failure mode of these barrels, including quantifying the leak rate. In this study, the use of a custom-calibrated, long-wave microbolometer camera is demonstrated to seek new protection methods for rack-stored distilled spirits. Individual oak barrels ranging between 200 L and 500 L filled with 75%/25% ethanol/water were exposed to both propane gas fires and pure ethanol pool fires. The IR camera was used to see through the smoke and flames showing the location of the leaks. The increase in HRR due to the leaked content was measured using gas calorimetry of the combustion products. This study showed that barrels leaked at a rate of approximately 4-8 lpm, resulting in heat release rates ranging between 1.2 and 2.4 MW. These numbers are confirmed by the quantitative measurements of gaseous H2O and CO¬2 in the exhaust. Surface temperature of the exposed oak could reach temperatures up to 750ºC.

  4. Twenty years of barrel-stave flextensional transducer technology in Canada

    NASA Astrophysics Data System (ADS)

    Jones, Dennis F.

    2005-04-01

    The barrel-stave flextensional transducer, a compact underwater sound source, was conceived at DRDC Atlantic in 1986 [G. W. McMahon and D. F. Jones, U.S. Patent No. 4,922,470 (1 May 1990); Canadian Patent No. 1,285,646 (2 July 1991)]. Over the years, five barrel-stave designs belonging to three flextensional classes were built and tested at DRDC Atlantic. Three Class I transducers with operating frequencies ranging from 800 to 1600 Hz were integrated into submarine communications buoys, low frequency active horizontal projector arrays, and a broadband sonar towbody. A high-power Class II and broadband (1-7 kHz) Class III transducer were deployed under the ice in the Lincoln Sea for research related to rapidly deployable surveillance systems. These barrel-stave flextensional transducers have also supported a variety of marine mammal studies including vocal mimicry in long-finned pilot whales, coda dialects in sperm whales, and the R&D of acoustic detection and tracking systems for endangered northern right whales. In August 2004 a barrel-stave transducer was used to lure a trapped juvenile humpback whale to the sluice gates of a tidal generating station on the Annapolis River in Nova Scotia by transmitting humpback whale calls underwater. The acoustic performance parameters for all 5 transducers will be presented.

  5. OMPcontact: An Outer Membrane Protein Inter-Barrel Residue Contact Prediction Method.

    PubMed

    Zhang, Li; Wang, Han; Yan, Lun; Su, Lingtao; Xu, Dong

    2017-03-01

    In the two transmembrane protein types, outer membrane proteins (OMPs) perform diverse important biochemical functions, including substrate transport and passive nutrient uptake and intake. Hence their 3D structures are expected to reveal these functions. Because experimental structures are scarce, predicted 3D structures are more adapted to OMP research instead, and the inter-barrel residue contact is becoming one of the most remarkable features, improving prediction accuracy by describing the structural information of OMPs. To predict OMP structures accurately, we explored an OMP inter-barrel residue contact prediction method: OMPcontact. Multiple OMP-specific features were integrated in the method, including residue evolutionary covariation, topology-based transmembrane segment relative residue position, OMP lipid layer accessibility, and residue evolution conservation. These features describe the properties of a residue pair in different respects: sequential, structural, evolutionary, and biochemical. Within a 3-residues slide window, a Support Vector Machine (SVM) could accurately determinate the inter-barrel contact residue pair using above features. A 5-fold cross-valuation process was applied in testing the OMPcontact performance against a non-redundant OMP set with 75 samples inside. The tests compared four evolutionary covariation methods and screen analyzed the adaptive ones for inter-barrel contact prediction. The results showed our method not only efficiently realized the prediction, but also scored the possibility for residue pairs reliably. This is expected to improve OMP tertiary structure prediction. Therefore, OMPcontact will be helpful in compiling a structural census of outer membrane protein.

  6. 49 CFR 178.607 - Cooperage test for bung-type wooden barrels.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Cooperage test for bung-type wooden barrels. 178.607 Section 178.607 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SPECIFICATIONS FOR PACKAGINGS Testing of Non-bulk...

  7. Determination of Heat Transfer Coefficient in a Gun Barrel from Experimental Data

    DTIC Science & Technology

    1985-01-01

    Barrels, BRL-R- 1740, September 1974. AD #BOOO71L. Mark W. Zemansky , Heat and Thermodynamics, McGraw-Hill Book Company Inc., New York, 1957. 3 Max Jacob...September 1974. AD #BOO17lL. 2. Mark W. Zemansky , Heat and Thermodynamics, McGraw-Hill Book Company Inc., New York, 1957. 3. Max Jacob, Heat Transfer, Vol. 1

  8. 33 CFR 135.103 - Levy and payment of barrel fee on OCS oil.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Levy and payment of barrel fee on OCS oil. 135.103 Section 135.103 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION...

  9. 33 CFR 135.103 - Levy and payment of barrel fee on OCS oil.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Levy and payment of barrel fee on OCS oil. 135.103 Section 135.103 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION...

  10. 33 CFR 135.103 - Levy and payment of barrel fee on OCS oil.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Levy and payment of barrel fee on OCS oil. 135.103 Section 135.103 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION...

  11. 33 CFR 135.103 - Levy and payment of barrel fee on OCS oil.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Levy and payment of barrel fee on OCS oil. 135.103 Section 135.103 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION...

  12. 77 FR 37321 - Safety Zone, Barrel Recovery, Lake Superior; Duluth, MN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-21

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone, Barrel Recovery, Lake Superior; Duluth, MN..., Duluth, MN. This safety zone is precautionary to protect recreational vessels and marine traffic from any... Brighton Beach, up to approximately 4 miles offshore on Lake Superior, Duluth, MN. This safety zone will be...

  13. Construction and test of the final CMS Barrel Drift Tube Muon Chamber prototype

    NASA Astrophysics Data System (ADS)

    Aguilar-Benítez, M.; Alberdi, J.; Arneodo, M.; Banicz, K.; Benettoni, M.; Benvenuti, A.; Bethke, S.; Cerrada, M.; Cirio, R.; Colino, N.; Conti, E.; Dallavalle, M.; Daniel, M.; Dattola, D.; Daudo, F.; De Giorgi, M.; Dosselli, U.; Fanfani, A.; Fanin, C.; Fouz, M. C.; Gasparini, F.; Gasparini, U.; Giacomelli, P.; Giordano, V.; Gonella, F.; Grandi, C.; Guaita, P.; Guerzoni, M.; Lacaprara, S.; Lippi, I.; Marcellini, S.; Marín, J.; Martinelli, R.; Maselli, S.; Meneguzzo, A.; Migliore, E.; Mocholí, J.; Monaco, V.; Montanari, A.; Montanari, C.; Odorici, F.; Oller, J. C.; Paoletti, S.; Passaseo, M.; Pegoraro, M.; Peroni, C.; Puerta, J.; Reithler, H.; Romero, A.; Romero, L.; Ronchese, P.; Rossi, A. M.; Rovelli, T.; Sacchi, R.; Salicio, J. M.; Staiano, A.; Steinbeck, T.; Torassa, E.; Travaglini, R.; Ventura, L.; Ventura, S.; Vitelli, A.; Voetee, F.; Wegner, M.; Willmott, C.; Zotto, P.; Zumerle, G.

    2002-03-01

    A prototype of the CMS Barrel Muon Detector incorporating all the features of the final chambers was built using the mass production assembly procedures and tools. The performance of this prototype was studied in a muon test beam at CERN and the results obtained are presented in this paper.

  14. Late emergence of the vibrissa direction selectivity map in the rat barrel cortex.

    PubMed

    Kremer, Yves; Léger, Jean-François; Goodman, Dan; Brette, Romain; Bourdieu, Laurent

    2011-07-20

    In the neocortex, neuronal selectivities for multiple sensorimotor modalities are often distributed in topographical maps thought to emerge during a restricted period in early postnatal development. Rodent barrel cortex contains a somatotopic map for vibrissa identity, but the existence of maps representing other tactile features has not been clearly demonstrated. We addressed the issue of the existence in the rat cortex of an intrabarrel map for vibrissa movement direction using in vivo two-photon imaging. We discovered that the emergence of a direction map in rat barrel cortex occurs long after all known critical periods in the somatosensory system. This map is remarkably specific, taking a pinwheel-like form centered near the barrel center and aligned to the barrel cortex somatotopy. We suggest that this map may arise from intracortical mechanisms and demonstrate by simulation that the combination of spike-timing-dependent plasticity at synapses between layer 4 and layer 2/3 and realistic pad stimulation is sufficient to produce such a map. Its late emergence long after other classical maps suggests that experience-dependent map formation and refinement continue throughout adult life.

  15. LINC Modeling of August 19, 2004 Queen City Barrel Company Fire In Cincinnati, OH

    SciTech Connect

    Dillon, M B; Nasstrom, J S; Baskett, R L; Pobanz, B M

    2004-09-14

    This report details the information received, assumptions made, actions taken, and products delivered by the Lawrence Livermore National Laboratory (LLNL) during the August 19, 2004 fire at the Queen City Barrel Company (QCB) in Cincinnati, OH. During the course of the event, LLNL provided four sets of plume model products to various Cincinnati emergency response organizations.

  16. Inverse determination of heat flux into a gun barrel using temperature sensors

    NASA Astrophysics Data System (ADS)

    Jablonski, Jonathan A.; Jablonski, Melissa N.

    2017-05-01

    A mathematical model is developed to describe the thermal response of a temperature sensor located within a gun barrel, which accounts for the time-constant of the sensor and a measurement bias. The model is inversely solved to estimate the total heat flux applied to the bore surface as well as the transient history of the applied heat flux for a given thermal response of a temperature sensor. A parametric study is conducted to determine the influence of sensor time-constant, sensor location within the gun barrel, and measurement bias on the accuracy of the estimated heat flux as applied to a 155mm gun barrel. It is found that the accuracy of the estimated heat flux improves as the time-constant of the sensor decreases, the sensor is located closer to the bore surface, and the measurement bias decreases. A regression model is provided to estimate that accuracy and it is shown how a typical thermocouple would perform at various locations through the thickness of the gun barrel.

  17. Evaluation of mRNA Localization Using Double Barrel Scanning Ion Conductance Microscopy.

    PubMed

    Nashimoto, Yuji; Takahashi, Yasufumi; Zhou, Yuanshu; Ito, Hidenori; Ida, Hiroki; Ino, Kosuke; Matsue, Tomokazu; Shiku, Hitoshi

    2016-07-26

    Information regarding spatial mRNA localization in single cells is necessary for a better understanding of cellular functions in tissues. Here, we report a method for evaluating localization of mRNA in single cells using double-barrel scanning ion conductance microscopy (SICM). Two barrels in a nanopipette were filled with aqueous and organic electrolyte solutions and used for SICM and as an electrochemical syringe, respectively. We confirmed that the organic phase barrel could be used to collect cytosol from living cells, which is a minute but sufficient amount to assess cellular status using qPCR analysis. The water phase barrel could be used for SICM to image topography with subcellular resolution, which could be used to determine positions for analyzing mRNA expression. This system was able to evaluate mRNA localization in single cells. After puncturing the cellular membrane in a minimally invasive manner, using SICM imaging as a guide, we collected a small amount cytosol from different positions within a single cell and showed that mRNA expression depends on cellular position. In this study, we show that SICM imaging can be utilized for the analysis of mRNA localization in single cells. In addition, we fully automated the pipet movement in the XYZ-directions during the puncturing processes, making it applicable as a high-throughput system for collecting cytosol and analyzing mRNA localization.

  18. EVALUATION OF EMISSIONS FROM THE OPEN BURNING OF HOUSEHOLD WASTES IN BARRELS - VOLUME 2. APPENDICES

    EPA Science Inventory

    The report gives results of a detailed emissions characterization study undertaken to examine, characterize, and quantify emissions from the simulated burning of household waste in barrels. The study evaluated two waste streams: that of an avid recycler, who removed most of the r...

  19. EVALUATION OF EMISSIONS FROM THE OPEN BURNING OF HOUSEHOLD WASTE IN BARRELS - VOLUME 1. TECHNICAL REPORT

    EPA Science Inventory

    The report gives results of a detailed emissions characterization study undertaken to examine, characterize, and quantify emissions from the simulated burning of household waste in barrels. The study evaluated two waste streams: that of an avid recycler, who removed most of the r...

  20. Studies of hadron-electron separators for the ZEUS barrel calorimeter

    SciTech Connect

    Ambats, I.; Bortz, D.; Connolly, A.

    1995-05-25

    Two possible upgrades, a shower maximum detector and a presampler, designed to improve the low energy electron/hadron separation capabilities of the ZEUS barrel calorimeter are described and test-beam results are reported. The presampler can also be used to correct for energy loss of particles traversing the dead material in front of the calorimeter.

  1. 27 CFR 478.113a - Importation of firearm barrels by nonlicensees.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2011-04-01 2010-04-01 true Importation of firearm barrels by nonlicensees. 478.113a Section 478.113a Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION COMMERCE IN...

  2. 27 CFR 478.113a - Importation of firearm barrels by nonlicensees.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2013-04-01 2013-04-01 false Importation of firearm barrels by nonlicensees. 478.113a Section 478.113a Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION COMMERCE IN...

  3. 27 CFR 478.113a - Importation of firearm barrels by nonlicensees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Importation of firearm barrels by nonlicensees. 478.113a Section 478.113a Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION COMMERCE IN...

  4. 27 CFR 478.113a - Importation of firearm barrels by nonlicensees.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2012-04-01 2010-04-01 true Importation of firearm barrels by nonlicensees. 478.113a Section 478.113a Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION COMMERCE IN...

  5. 27 CFR 478.113a - Importation of firearm barrels by nonlicensees.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2014-04-01 2014-04-01 false Importation of firearm barrels by nonlicensees. 478.113a Section 478.113a Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO, FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION COMMERCE IN...

  6. VARIABLES AFFECTING EMISSIONS OF PCDDS/FS FROM UNCONTROLLED COMBUSTION OF HOUSEHOLD WASTE IN BARRELS

    EPA Science Inventory

    The uncontrolled burning of household waste in barrels has recently been implicated as a major source of airborne emissions of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDDs/Fs). Based on the need to generate a more accurate emission factor for burn ba...

  7. Analysis of Fibular Single Graft and Fibular Double-barrel Graft for Mandibular Reconstruction

    PubMed Central

    Shimizu, Yusuke; Ihara, Jyun; Kishi, Kazuo

    2016-01-01

    Background: High-quality mandibular reconstruction using vascularized free fibular graft is necessary to provide an osseointegrated dental implant and fixed denture. An appropriate crown–implant ratio is needed, and a good match between bones is extremely important. There are no articles describing the analysis and evaluation of both the fibula and mandible in the same patients. Methods: Computed tomography images of both mandible and fibula of 80 patients were selected in a random manner. We measured bone height of the fibula and mandible at specified points and evaluated the difference of bone height between the fibula and mandible using fibular single or double-barrel grafts. Results: The percentage of patients who had a “good” result for a fibular single graft was only 13.8%. There was no significant difference in bone heights when analyzed by gender. Whether patients were dentulous or not had a large influence on the difference between fibular and mandibular bone heights. Most young patients, but only half of older patients, needed fibular double-barrel grafts. Overweight patients with a high body mass index more often needed fibular double-barrel grafts. Conclusions: For mandibular reconstruction using a fibular graft, preoperative analysis of the patient’s profile and proper use of a fibular single or double-barrel graft contribute to minimizing the difference between the height of the grafted fibula and native mandible and are keys to an ideal reconstruction with good cosmetics and function. PMID:27622091

  8. 33 CFR 135.103 - Levy and payment of barrel fee on OCS oil.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OCS oil. 135.103 Section 135.103 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OFFSHORE OIL POLLUTION COMPENSATION FUND Levy of Fees § 135.103 Levy and payment of barrel fee on OCS oil. (a) A fee of $.03...

  9. Assessment of Residential Rain Barrel Water Quality and Use in Cincinnati, Ohio

    EPA Science Inventory

    The collection, storage, and reuse of rainwater collected in rain barrels from urban rooftop areas assists municipalities in achieving stormwater management objectives and in some areas also serves as an adjunct resource for domestic water supplies. In this study, rainwater reuse...

  10. Assessment of Residential Rain Barrel Water Quality and Use in Cincinnati, Ohio

    EPA Science Inventory

    The collection, storage, and reuse of rainwater collected in rain barrels from urban rooftop areas assists municipalities in achieving stormwater management objectives and in some areas also serves as an adjunct resource for domestic water supplies. In this study, rainwater reuse...

  11. Metal dust deposition in a shotgun wound associated with barrel modification.

    PubMed

    Williams, Andrew S; Bowes, Matthew J

    2016-03-01

    Contact-range gunshot wounds commonly demonstrate deposition of black soot in and around the wound. Deposition of other visible pigments originating from the firearm has not been specifically described. In the current case, an adult male was found dead adjacent to a shotgun fixed in a vice grip with a modified, shortened barrel. A handheld, powered, metal grinding wheel was nearby. Autopsy revealed an intraoral gunshot wound, including soot deposition in and around the mouth and within the wound track. In addition, there was a peculiar, gray, lustrous film on the lips, gingiva, and anterior teeth. The material was concentrated around the most severe areas of injury in the anterior mouth and easily rubbed off with a cotton swab. It was not visualized in the rest of the mouth and not present in the larynx, or the esophagus. Overall, our opinion is that this unique, gray, lustrous film represents deposition of fine metallic dust that accumulated in the barrel of the shotgun during its modification with the grinding wheel. This type of unique pigment deposition should be recognized by forensic pathologists as possibly being related to the discharge of a firearm with a recently modified barrel or other cause for fine metallic dust accumulation within the barrel. Depending on the circumstances of the case, collection of samples of such metal dust deposits could be indicated for subsequent analysis.

  12. Npas4 Expression in Two Experimental Models of the Barrel Cortex Plasticity

    PubMed Central

    Kaliszewska, Aleksandra; Kossut, Malgorzata

    2015-01-01

    Npas4 has recently been identified as an important factor in brain plasticity, particularly in mechanisms of inhibitory control. Little is known about Npas4 expression in terms of cortical plasticity. In the present study expressions of Npas4 and the archetypal immediate early gene (IEG) c-Fos were investigated in the barrel cortex of mice after sensory deprivation (sparing one row of whiskers for 7 days) or sensory conditioning (pairing stimulation of one row of whiskers with aversive stimulus). Laser microdissection of individual barrel rows allowed for analysis of IEGs expression precisely in deprived and nondeprived barrels (in deprivation study) or stimulated and nonstimulated barrels (in conditioning study). Cortex activation by sensory conditioning was found to upregulate the expression of both Npas4 and c-Fos. Reorganization of cortical circuits triggered by removal of selected rows of whiskers strongly affected c-Fos but not Npas4 expression. We hypothesize that increased inhibitory synaptogenesis observed previously after conditioning may be mediated by Npas4 expression. PMID:25785202

  13. Analysis of Fibular Single Graft and Fibular Double-barrel Graft for Mandibular Reconstruction.

    PubMed

    Ishii, Naohiro; Shimizu, Yusuke; Ihara, Jyun; Kishi, Kazuo

    2016-08-01

    High-quality mandibular reconstruction using vascularized free fibular graft is necessary to provide an osseointegrated dental implant and fixed denture. An appropriate crown-implant ratio is needed, and a good match between bones is extremely important. There are no articles describing the analysis and evaluation of both the fibula and mandible in the same patients. Computed tomography images of both mandible and fibula of 80 patients were selected in a random manner. We measured bone height of the fibula and mandible at specified points and evaluated the difference of bone height between the fibula and mandible using fibular single or double-barrel grafts. The percentage of patients who had a "good" result for a fibular single graft was only 13.8%. There was no significant difference in bone heights when analyzed by gender. Whether patients were dentulous or not had a large influence on the difference between fibular and mandibular bone heights. Most young patients, but only half of older patients, needed fibular double-barrel grafts. Overweight patients with a high body mass index more often needed fibular double-barrel grafts. For mandibular reconstruction using a fibular graft, preoperative analysis of the patient's profile and proper use of a fibular single or double-barrel graft contribute to minimizing the difference between the height of the grafted fibula and native mandible and are keys to an ideal reconstruction with good cosmetics and function.

  14. PARAMETERS INFLUENCING EMISSIONS OF PCDDS/FS FROM OPEN BURNING OF HOUSEHOLD WASTE IN BARRELS

    EPA Science Inventory

    The paper reports results from tests that were designed to examine some of the factors influencing the emissions of polychlorinated-p-dioxins and polychlorinated dibenzofurans (PCDDs/Fs) from burn barrels. Based on the wide variability of emissions within duplicate-run sets, in ...

  15. EVALUATION OF EMISSIONS FROM THE OPEN BURNING OF HOUSEHOLD WASTES IN BARRELS - VOLUME 2. APPENDICES

    EPA Science Inventory

    The report gives results of a detailed emissions characterization study undertaken to examine, characterize, and quantify emissions from the simulated burning of household waste in barrels. The study evaluated two waste streams: that of an avid recycler, who removed most of the r...

  16. EVALUATION OF EMISSIONS FROM THE OPEN BURNING OF HOUSEHOLD WASTE IN BARRELS - VOLUME 1. TECHNICAL REPORT

    EPA Science Inventory

    The report gives results of a detailed emissions characterization study undertaken to examine, characterize, and quantify emissions from the simulated burning of household waste in barrels. The study evaluated two waste streams: that of an avid recycler, who removed most of the r...

  17. 7 CFR 58.425 - Conveyor for moving and draining block or barrel cheese.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Conveyor for moving and draining block or barrel cheese. 58.425 Section 58.425 Agriculture Regulations of the Department of Agriculture (Continued... and Grading Service 1 Equipment and Utensils § 58.425 Conveyor for moving and draining block or...

  18. 7 CFR 58.425 - Conveyor for moving and draining block or barrel cheese.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Conveyor for moving and draining block or barrel cheese. 58.425 Section 58.425 Agriculture Regulations of the Department of Agriculture (Continued... and Grading Service 1 Equipment and Utensils § 58.425 Conveyor for moving and draining block or...

  19. 7 CFR 58.425 - Conveyor for moving and draining block or barrel cheese.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Conveyor for moving and draining block or barrel cheese. 58.425 Section 58.425 Agriculture Regulations of the Department of Agriculture (Continued... and Grading Service 1 Equipment and Utensils § 58.425 Conveyor for moving and draining block or...

  20. 7 CFR 58.425 - Conveyor for moving and draining block or barrel cheese.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Conveyor for moving and draining block or barrel cheese. 58.425 Section 58.425 Agriculture Regulations of the Department of Agriculture (Continued... cheese. The conveyor shall be constructed so that it will not contaminate the cheese and be easily...

  1. 7 CFR 58.425 - Conveyor for moving and draining block or barrel cheese.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Conveyor for moving and draining block or barrel cheese. 58.425 Section 58.425 Agriculture Regulations of the Department of Agriculture (Continued... cheese. The conveyor shall be constructed so that it will not contaminate the cheese and be easily...

  2. 3. PHOTOCOPY OF 1/2 OF CA. 1880 STREOCARD SHOWING 'BARREL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. PHOTOCOPY OF 1/2 OF CA. 1880 STREOCARD SHOWING 'BARREL SHOT' VIEW LOOKING DOWN THE LENGTH OF LOWER DECK. JAMES CREMER, PHOTOGRAPHER AND PUBLISHER, 18 SOUTH EIGHTH STREET, PHILADELPHIA. - Callowhill Street Bridge, Schuylkill River at Spring Garden & Callowhill Streets, Philadelphia, Philadelphia County, PA

  3. Fabrication of a glucose biosensor based on inserted barrel plating gold electrodes.

    PubMed

    Hsu, Cheng-Teng; Chung, Hsieh-Hsun; Tsai, Dong-Mung; Fang, Mei-Yen; Hsiao, Hung-Chan; Zen, Jyh-Myng

    2009-01-01

    We demonstrate here the application of barrel plating gold electrodes for fabricating a new type of disposable amperometric glucose biosensor. It is prepared by inserting two barrel plating gold electrodes onto an injection molding plastic base followed by immobilizing with a bioreagent layer and membrane on the electrode surface. The primary function of barrel plating is to provide an economical way to electroplate manufactured parts. The manufacture procedure is simple and can increase the fabrication precision for automation in mass production. At the two-electrode system, the detection of glucose is linear up to 800 mg/dL (i.e., 44.5 mM, r(2) > 0.99) in pH 7.4 PBS with a sensitivity of 0.71 microA/mM. Excellent sensor-to-sensor reproducibility shows coefficients of variation of only 0.8-1.4% for the detection of 56.5-561.0 mg/dL glucose. In laboratory trials 176 capillary blood samples with a range of 30-572 mg/dL glucose are used to evaluate the clinical application of the biosensor. A good linear correlation is observed between the measured values of the proposed biosensor and laboratory reference. Error grid analysis verifies that the proposed technique is promising in fabricating biosensor strips on a mass scale. As successfully demonstrated by using whole blood glucose as a model analyte, the fabrication technique can extend into other barrel plating noble metal electrodes for various applications.

  4. Superior long-term stability of a glucose biosensor based on inserted barrel plating gold electrodes.

    PubMed

    Hsu, Cheng-Teng; Hsiao, Hung-Chan; Fang, Mei-Yen; Zen, Jyh-Myng

    2009-10-15

    Disposable one shot usage blood glucose strips are routinely used in the diagnosis and management of diabetes mellitus and their performance can vary greatly. In this paper we critically evaluated the long-term stability of glucose strips made of barrel plating gold electrodes. Compared to other glucose biosensing platforms of vapor deposited palladium and screen printed carbon electrodes, the proposed glucose biosensor was found to show the best stability among the three biosensing platforms in thermal acceleration experiments at 40 degrees C for 6 months with an average bias of 3.4% at glucose concentrations of 5-20 mM. The precision test of this barrel plating gold glucose biosensor also showed the best performance (coefficients of variation in the range of 1.4-2.4%) in thermal acceleration experiments at 40 degrees C, 50 degrees C and 70 degrees C for 27 days. Error grid analysis revealed that all measurements fell in zone A and zone B. Regression analysis showed no significant difference between the proposed biosensor and the reference method at 99% confidence level. The amperometric glucose biosensor fabricated by inserting two barrel plating gold electrodes onto an injection-molding plastic base followed by immobilizing with a bio-reagent layer and membrane was very impressive with a long-term stability up to 2.5 years at 25 degrees C. Overall, these results indicated that the glucose oxidase/barrel plating gold biosensing platform is ideal for long-term accurate glycemic control.

  5. Effects of Dimethyl Sulfoxide on Neuronal Response Characteristics in Deep Layers of Rat Barrel Cortex

    PubMed Central

    Soltani, Narjes; Mohammadi, Elham; Allahtavakoli, Mohammad; Shamsizadeh, Ali; Roohbakhsh, Ali; Haghparast, Abbas

    2016-01-01

    Introduction: Dimethyl sulfoxide (DMSO) is a chemical often used as a solvent for water-insoluble drugs. In this study, we evaluated the effect of intracerebroventricular (ICV) administration of DMSO on neural response characteristics (in 1200–1500 μm depth) of the rat barrel cortex. Methods: DMSO solution was prepared in 10% v/v concentration and injected into the lateral ventricle of rats. Neuronal spontaneous activity and neuronal responses to deflection of the principal whisker (PW) and adjacent whisker (AW) were recorded in barrel cortex. A condition test ratio (CTR) was used to measure inhibitory receptive fields in barrel cortex. Results: The results showed that both PW and AW evoked ON and OFF responses, neuronal spontaneous activity and inhibitory receptive fields did not change following ICV administration of DMSO. Conclusion: Results of this study suggest that acute ICV administration of 10% DMSO did not modulate the electrophysiological characteristics of neurons in the l deep ayers of rat barrel cortex. PMID:27563414

  6. High speed machining of space shuttle external tank liquid hydrogen barrel panel

    NASA Technical Reports Server (NTRS)

    Hankins, J. D.

    1983-01-01

    Actual and projected optimum High Speed Machining data for producing shuttle external tank liquid hydrogen barrel panels of aluminum alloy 2219-T87 are reported. The data included various machining parameters; e.g., spindle speeds, cutting speed, table feed, chip load, metal removal rate, horsepower, cutting efficiency, cutter wear (lack of) and chip removal methods.

  7. Polyphenols in red wine aged in acacia (Robinia pseudoacacia) and oak (Quercus petraea) wood barrels.

    PubMed

    Sanz, Miriam; Fernández de Simón, Brígida; Esteruelas, Enrique; Muñoz, Angel Ma; Cadahía, Estrella; Hernández, Ma Teresa; Estrella, Isabel; Martinez, Juana

    2012-06-30

    Polyphenolic composition of two Syrah wines aged during 6 or 12 months in medium toasting acacia and oak 225L barrels was studied by LC-DAD-ESI/MS. A total of 43 nonanthocyanic phenolic compounds were found in all wines, and other 15 compounds only in the wines from acacia barrels. Thus, the nonanthocyanic phenolic profile could be a useful tool to identify the wines aged in acacia barrels. Among all of them the dihydrorobinetin highlights because of its high levels, but also robinetin, 2,4-dihydroxybenzaldehyde, a tetrahydroxydihydroflavonol, fustin, butin, a trihydroxymethoxydihydroflavonol and 2,4-dihydroxybenzoic acid were detected at appreciable levels in wines during aging in acacia barrels, and could be used as phenolic markers for authenticity purposes. Although longer contact time with acacia wood mean higher concentrations of phenolic markers found in wines, the identification of these wines will also be easy after short aging times due the high levels reached by these compounds, even after only 2 months of aging.

  8. MOSFET level 1 and 2 models in APLAC

    NASA Astrophysics Data System (ADS)

    Kankkunen, A.; Andersson, M.; Valtonen, M.

    The Analysis Program for Linear Active Circuits (APLAC) implementations are documented of SPICE level 1 and 2 MOS models. First a set of mappings is derived for handling NMOS and PMOS transistors in all operating regions based on the equations of an NMOS transistor with V(ds) = or greater than 0. Then the model equations of the NMOS transistor are presented. Two drain current models are covered. These are SPICE level 1 and SPICE level 2. The documentation consists of all the equations required for the implementation including the substrate diode model, temperature dependencies, and noise equations. The intrinsic charge models presented are the simplified Yang-Chatterjee models and the Ward-Dutton model. Also the extrinsic capacitance model is documented.

  9. Academic performance and student engagement in level 1 physics undergraduates

    NASA Astrophysics Data System (ADS)

    Casey, M. M.; McVitie, S.

    2009-09-01

    At the beginning of academic year 2007-08, staff in the Department of Physics and Astronomy at the University of Glasgow started to implement a number of substantial changes to the administration of the level 1 physics undergraduate class. The main aims were to improve the academic performance and progression statistics. With this in mind, a comprehensive system of learning support was introduced, the main remit being the provision of an improved personal contact and academic monitoring and support strategy for all students at level 1. The effects of low engagement with compulsory continuous assessment components had already been observed to have a significant effect on students sitting in the middle of the grade curve. Analysis of data from the 2007-08 class showed that even some nominally high-achieving students achieved lowered grades due to the effects of low engagement. Nonetheless, academic and other support measures put in place during 2007-08 played a part in raising the passrate for the level 1 physics class by approximately 8% as well as raising the progression rate by approximately 10%.

  10. Laser Magneto-Optic Rotation Spectrometer (LMORS)

    DTIC Science & Technology

    1998-01-01

    traditional method of measuring atomic concentrations uses atomic absorption spectroscopy (AAS), herein referred to as an AAS 15 spectrometer...MOR spectrometer of the present invention. Fig. 2 illustrates a calibration curve for a conventional 10 atomic absorption spectroscopy (AAS

  11. All-atom 3D structure prediction of transmembrane β-barrel proteins from sequences

    PubMed Central

    Hayat, Sikander; Sander, Chris; Marks, Debora S.

    2015-01-01

    Transmembrane β-barrels (TMBs) carry out major functions in substrate transport and protein biogenesis but experimental determination of their 3D structure is challenging. Encouraged by successful de novo 3D structure prediction of globular and α-helical membrane proteins from sequence alignments alone, we developed an approach to predict the 3D structure of TMBs. The approach combines the maximum-entropy evolutionary coupling method for predicting residue contacts (EVfold) with a machine-learning approach (boctopus2) for predicting β-strands in the barrel. In a blinded test for 19 TMB proteins of known structure that have a sufficient number of diverse homologous sequences available, this combined method (EVfold_bb) predicts hydrogen-bonded residue pairs between adjacent β-strands at an accuracy of ∼70%. This accuracy is sufficient for the generation of all-atom 3D models. In the transmembrane barrel region, the average 3D structure accuracy [template-modeling (TM) score] of top-ranked models is 0.54 (ranging from 0.36 to 0.85), with a higher (44%) number of residue pairs in correct strand–strand registration than in earlier methods (18%). Although the nonbarrel regions are predicted less accurately overall, the evolutionary couplings identify some highly constrained loop residues and, for FecA protein, the barrel including the structure of a plug domain can be accurately modeled (TM score = 0.68). Lower prediction accuracy tends to be associated with insufficient sequence information and we therefore expect increasing numbers of β-barrel families to become accessible to accurate 3D structure prediction as the number of available sequences increases. PMID:25858953

  12. All-atom 3D structure prediction of transmembrane β-barrel proteins from sequences.

    PubMed

    Hayat, Sikander; Sander, Chris; Marks, Debora S; Elofsson, Arne

    2015-04-28

    Transmembrane β-barrels (TMBs) carry out major functions in substrate transport and protein biogenesis but experimental determination of their 3D structure is challenging. Encouraged by successful de novo 3D structure prediction of globular and α-helical membrane proteins from sequence alignments alone, we developed an approach to predict the 3D structure of TMBs. The approach combines the maximum-entropy evolutionary coupling method for predicting residue contacts (EVfold) with a machine-learning approach (boctopus2) for predicting β-strands in the barrel. In a blinded test for 19 TMB proteins of known structure that have a sufficient number of diverse homologous sequences available, this combined method (EVfold_bb) predicts hydrogen-bonded residue pairs between adjacent β-strands at an accuracy of ∼70%. This accuracy is sufficient for the generation of all-atom 3D models. In the transmembrane barrel region, the average 3D structure accuracy [template-modeling (TM) score] of top-ranked models is 0.54 (ranging from 0.36 to 0.85), with a higher (44%) number of residue pairs in correct strand-strand registration than in earlier methods (18%). Although the nonbarrel regions are predicted less accurately overall, the evolutionary couplings identify some highly constrained loop residues and, for FecA protein, the barrel including the structure of a plug domain can be accurately modeled (TM score = 0.68). Lower prediction accuracy tends to be associated with insufficient sequence information and we therefore expect increasing numbers of β-barrel families to become accessible to accurate 3D structure prediction as the number of available sequences increases.

  13. A wireline piston core barrel for sampling cohesionless sand and gravel below the water table

    USGS Publications Warehouse

    Zapico, Michael M.; Vales, Samuel; Cherry, John A.

    1987-01-01

    A coring device has been developed to obtain long and minimally disturbed samples of saturated cohesionless sand and gravel. The coring device, which includes a wireline and piston, was developed specifically for use during hollow-stem auger drilling but it also offers possibilities for cable tool and rotary drilling. The core barrel consists of an inner liner made of inexpensive aluminum or plastic tubing, a piston for core recovery, and an exterior steel housing that protects the liner when the core barrel is driven into the aquifer. The core barrel, which is approximately 1.6m (5.6 feet) long, is advanced ahead of the lead auger by hammering at the surface on drill rods that are attached to the core barrel. After the sampler has been driven 1.5m (5 feet), the drill rods are detached and a wireline is used to hoist the core barrel, with the sample contained in the aluminum or plastic liner, to the surface. A vacuum developed by the piston during the coring operation provides good recovery of both the sediment and aquifer fluids contained in the sediment. In the field the sample tubes can be easily split along their length for on-site inspection or they can be capped with the pore water fluids inside and transported to the laboratory. The cores are 5cm (2 inches) in diameter by 1.5m (5 feet) long. Core acquisition to depths of 35m (115 feet), with a recovery greater than 90 percent, has become routine in University of Waterloo aquifer studies. A large diameter (12.7cm [5 inch]) version has also been used successfully. Nearly continuous sample sequences from sand and gravel aquifers have been obtained for studies of sedimentology, hydraulic conductivity, hydrogeochemistry and microbiology.

  14. Measuring Transmission Efficiencies Of Mass Spectrometers

    NASA Technical Reports Server (NTRS)

    Srivastava, Santosh K.

    1989-01-01

    Coincidence counts yield absolute efficiencies. System measures mass-dependent transmission efficiencies of mass spectrometers, using coincidence-counting techniques reminiscent of those used for many years in calibration of detectors for subatomic particles. Coincidences between detected ions and electrons producing them counted during operation of mass spectrometer. Under certain assumptions regarding inelastic scattering of electrons, electron/ion-coincidence count is direct measure of transmission efficiency of spectrometer. When fully developed, system compact, portable, and used routinely to calibrate mass spectrometers.

  15. Electron/proton spectrometer certification documentation analyses

    NASA Technical Reports Server (NTRS)

    Gleeson, P.

    1972-01-01

    A compilation of analyses generated during the development of the electron-proton spectrometer for the Skylab program is presented. The data documents the analyses required by the electron-proton spectrometer verification plan. The verification plan was generated to satisfy the ancillary hardware requirements of the Apollo Applications program. The certification of the spectrometer requires that various tests, inspections, and analyses be documented, approved, and accepted by reliability and quality control personnel of the spectrometer development program.

  16. Sample rotating turntable kit for infrared spectrometers

    DOEpatents

    Eckels, Joel Del; Klunder, Gregory L.

    2008-03-04

    An infrared spectrometer sample rotating turntable kit has a rotatable sample cup containing the sample. The infrared spectrometer has an infrared spectrometer probe for analyzing the sample and the rotatable sample cup is adapted to receive the infrared spectrometer probe. A reflectance standard is located in the rotatable sample cup. A sleeve is positioned proximate the sample cup and adapted to receive the probe. A rotator rotates the rotatable sample cup. A battery is connected to the rotator.

  17. Electron spectrometer for gas-phase spectroscopy

    SciTech Connect

    Bozek, J.D.; Schlachter, A.S.

    1997-04-01

    An electron spectrometer for high-resolution spectroscopy of gaseous samples using synchrotron radiation has been designed and constructed. The spectrometer consists of a gas cell, cylindrical electrostatic lens, spherical-sector electron energy analyzer, position-sensitive detector and associated power supplies, electronics and vacuum pumps. Details of the spectrometer design are presented together with some representative spectra.

  18. Advanced Mass Spectrometers for Hydrogen Isotope Analyses

    SciTech Connect

    Chastagner, P.

    2001-08-01

    This report is a summary of the results of a joint Savannah River Laboratory (SRL) - Savannah River Plant (SRP) ''Hydrogen Isotope Mass Spectrometer Evaluation Program''. The program was undertaken to evaluate two prototype hydrogen isotope mass spectrometers and obtain sufficient data to permit SRP personnel to specify the mass spectrometers to replace obsolete instruments.

  19. On-chip plasmonic spectrometer.

    PubMed

    Tsur, Yuval; Arie, Ady

    2016-08-01

    We report a numerical and experimental study of an on-chip optical spectrometer, utilizing propagating surface plasmon polaritons in the telecom spectral range. The device is based on two holographic gratings, one for coupling, and the other for decoupling free-space radiation with the surface plasmons. This 800 μm×100 μm on-chip spectrometer resolves 17 channels spectrally separated by 3.1 nm, spanning a freely tunable spectral window, and is based on standard lithography fabrication technology. We propose two potential applications for this new device; the first employs the holographic control over the amplitude and phase of the input spectrum, for intrinsically filtering unwanted frequencies, like pump radiation in Raman spectroscopy. The second prospect utilizes the unique plasmonic field enhancement at the metal-dielectric boundary for the spectral analysis of very small samples (e.g., Mie scatterers) placed between the two gratings.

  20. Imaging X-ray spectrometer

    NASA Technical Reports Server (NTRS)

    Grant, P. A.; Jackson, J. W., Jr.; Alcorn, G. E.; Marshall, F. E. (Inventor)

    1984-01-01

    An X-ray spectrometer for providing imaging and energy resolution of an X-ray source is described. This spectrometer is comprised of a thick silicon wafer having an embedded matrix or grid of aluminum completely through the wafer fabricated, for example, by thermal migration. The aluminum matrix defines the walls of a rectangular array of silicon X-ray detector cells or pixels. A thermally diffused aluminum electrode is also formed centrally through each of the silicon cells with biasing means being connected to the aluminum cell walls and causes lateral charge carrier depletion between the cell walls so that incident X-ray energy causes a photoelectric reaction within the silicon producing collectible charge carriers in the form of electrons which are collected and used for imaging.

  1. Concerning the Spatial Heterodyne Spectrometer

    SciTech Connect

    Lenzner, Matthias; Diels, Jean -Claude

    2016-01-22

    A modified Spatial Heterodyne Spectrometer (SHS) is used for measuring atomic emission spectra with high resolution. This device is basically a Fourier Transform Spectrometer, but the Fourier transform is taken in the directions perpendicular to the optical propagation and heterodyned around one preset wavelength. In recent descriptions of this device, one specific phenomenon - the tilt of the energy front of wave packets when diffracted from a grating - was neglected. This led to an overestimate of the resolving power of this spectrograph, especially in situations when the coherence length of the radiation under test is in the order of the effective aperture of the device. In conclusion, the limits of usability are shown here together with some measurements of known spectral lines.

  2. Concerning the Spatial Heterodyne Spectrometer

    DOE PAGES

    Lenzner, Matthias; Diels, Jean -Claude

    2016-01-22

    A modified Spatial Heterodyne Spectrometer (SHS) is used for measuring atomic emission spectra with high resolution. This device is basically a Fourier Transform Spectrometer, but the Fourier transform is taken in the directions perpendicular to the optical propagation and heterodyned around one preset wavelength. In recent descriptions of this device, one specific phenomenon - the tilt of the energy front of wave packets when diffracted from a grating - was neglected. This led to an overestimate of the resolving power of this spectrograph, especially in situations when the coherence length of the radiation under test is in the order ofmore » the effective aperture of the device. In conclusion, the limits of usability are shown here together with some measurements of known spectral lines.« less

  3. SENTINEL-2 Level 1 Products and Image Processing Performances

    NASA Astrophysics Data System (ADS)

    Baillarin, S. J.; Meygret, A.; Dechoz, C.; Petrucci, B.; Lacherade, S.; Tremas, T.; Isola, C.; Martimort, P.; Spoto, F.

    2012-07-01

    In partnership with the European Commission and in the frame of the Global Monitoring for Environment and Security (GMES) program, the European Space Agency (ESA) is developing the Sentinel-2 optical imaging mission devoted to the operational monitoring of land and coastal areas. The Sentinel-2 mission is based on a satellites constellation deployed in polar sun-synchronous orbit. While ensuring data continuity of former SPOT and LANDSAT multi-spectral missions, Sentinel-2 will also offer wide improvements such as a unique combination of global coverage with a wide field of view (290 km), a high revisit (5 days with two satellites), a high resolution (10 m, 20 m and 60 m) and multi-spectral imagery (13 spectral bands in visible and shortwave infra-red domains). In this context, the Centre National d'Etudes Spatiales (CNES) supports ESA to define the system image products and to prototype the relevant image processing techniques. This paper offers, first, an overview of the Sentinel-2 system and then, introduces the image products delivered by the ground processing: the Level-0 and Level-1A are system products which correspond to respectively raw compressed and uncompressed data (limited to internal calibration purposes), the Level-1B is the first public product: it comprises radiometric corrections (dark signal, pixels response non uniformity, crosstalk, defective pixels, restoration, and binning for 60 m bands); and an enhanced physical geometric model appended to the product but not applied, the Level-1C provides ortho-rectified top of atmosphere reflectance with a sub-pixel multi-spectral and multi-date registration; a cloud and land/water mask is associated to the product. Note that the cloud mask also provides an indication about cirrus. The ground sampling distance of Level-1C product will be 10 m, 20 m or 60 m according to the band. The final Level-1C product is tiled following a pre-defined grid of 100x100 km2, based on UTM/WGS84 reference frame. The

  4. Critical Design Decisions of The Planck LFI Level 1 Software

    NASA Astrophysics Data System (ADS)

    Morisset, N.; Rohlfs, R.; Türler, M.; Meharga, M.; Binko, P.; Beck, M.; Frailis, M.; Zacchei, A.

    2010-12-01

    The PLANCK satellite with two on-board instruments, a Low Frequency Instrument (LFI) and a High Frequency Instrument (HFI) has been launched on May 14th with Ariane 5. The ISDC Data Centre for Astrophysics in Versoix, Switzerland has developed and maintains the Planck LFI Level 1 software for the Data Processing Centre (DPC) in Trieste, Italy. The main tasks of the Level 1 processing are to retrieve the daily available scientific and housekeeping (HK) data of the LFI instrument, the Sorption Cooler and the 4k Cooler data from Mission Operation Centre (MOC) in Darmstadt; to sort them by time and by type (detector, observing mode, etc...); to extract the spacecraft attitude information from auxiliary files; to flag the data according to several criteria; and to archive the resulting Time Ordered Information (TOI), which will then be used to produce maps of the sky in different spectral bands. The output of the Level 1 software are the TOI files in FITS format, later ingested into the Data Management Component (DMC) database. This software has been used during different phases of the LFI instrument development. We started to reuse some ISDC components for the LFI Qualification Model (QM) and we completely rework the software for the Flight Model (FM). This was motivated by critical design decisions taken jointly with the DPC. The main questions were: a) the choice of the data format: FITS or DMC? b) the design of the pipelines: use of the Planck Process Coordinator (ProC) or a simple Perl script? c) do we adapt the existing QM software or do we restart from scratch? The timeline and available manpower are also important issues to be taken into account. We present here the orientation of our choices and discuss their pertinence based on the experience of the final pre-launch tests and the start of real Planck LFI operations.

  5. Fast Spectrometer Construction and Testing

    NASA Astrophysics Data System (ADS)

    Menke, John

    2012-05-01

    This paper describes the construction and operation of a medium resolution spectrometer used in the visual wavelength range. It is homebuilt, but has built in guiding and calibration, is fully remote operable, and operates at a resolution R=3000. It features a fast f3.5 system, which allows it to be used with a fast telescope (18 inch f3.5) with no Barlow or other optical matching devices.

  6. Raman Spectrometer with Microprobe Capability.

    DTIC Science & Technology

    1986-01-15

    CLASSIFICATION O UNCLASSIFIEOIUNLIMITED 0 SAME AS RPT. DTIC USERS Unclassified 22# NAME OF RESPONSIBLE oiNDiviDu? 2jkL TELEPHONE (Include Area Cd)2.OFFICE...spectrometer with microprobe capability. The microprobe capability allows Raman measurements to be performed on a localized area with a resolution of 1.0...first our purchase process. The instrument actually purchased is then described. Preliminary Raman spectral data in several of the above areas is

  7. Portable Tandem Mass Spectrometer Analyzer

    DTIC Science & Technology

    1991-07-01

    The planned instrument was to be small enough to be portable in small vehicles and was to be able to use either an atmospheric pressure ion source or a...conventional electron impact/chemical ionization ion source. In order to accomplish these developments an atmospheric pressure ionization source was...developed for a compact, commercially available tandem quadrupole mass spectrometer. This ion source could be readily exchanged with the conventional

  8. Word Frequency Analysis. MOS: 12B. Skill Levels 1 & 2.

    DTIC Science & Technology

    1981-05-01

    Subtitle) ’ S. TYPE &F REPORT & PERIOD COVERED Word Frequency Analysis Final 1Si: /63 , 6. PERFORMING ORG. REPORT NUMBER Skill Level 7. AUTIiOR(,) 0...Word Frequency Analysis (WFA) reports were reproduced exactly as generated via computer printout. The prime users of this document were fully cognizant...AD-A117 203 ARMY TRAINING DEVELOPMENTS INST FORT MONROE VA F/B 5/9 WORD FREQUENCY ANALYSIS . MOSS 128. SKILL LEVELS 1 a 2.4U) MAY 81 A A LON O

  9. MODIS. Volume 1: MODIS level 1A software baseline requirements

    NASA Technical Reports Server (NTRS)

    Masuoka, Edward; Fleig, Albert; Ardanuy, Philip; Goff, Thomas; Carpenter, Lloyd; Solomon, Carl; Storey, James

    1994-01-01

    This document describes the level 1A software requirements for the moderate resolution imaging spectroradiometer (MODIS) instrument. This includes internal and external requirements. Internal requirements include functional, operational, and data processing as well as performance, quality, safety, and security engineering requirements. External requirements include those imposed by data archive and distribution systems (DADS); scheduling, control, monitoring, and accounting (SCMA); product management (PM) system; MODIS log; and product generation system (PGS). Implementation constraints and requirements for adapting the software to the physical environment are also included.

  10. Solution-focused group therapy for level 1 substance abusers.

    PubMed

    Smock, Sara A; Trepper, Terry S; Wetchler, Joseph L; McCollum, Eric E; Ray, Rose; Pierce, Kent

    2008-01-01

    The present study compared solution-focused group therapy (SFGT) with a traditional problem-focused treatment for level 1 substance abusers. Outcome research on the effectiveness of solution-focused group therapy is minimal, especially in treating substance abusers. In the present study, clients were measured before and after treatment to determine therapeutic effectiveness. Clients in the solution-focused group significantly improved on both the Beck Depression Inventory and the Outcome Questionnaire. The clients in the comparison group did not improve significantly on either measure. Therapist skill level and adherence to theoretical models were measured in each group to reduce confounding variables.

  11. Word Frequency Analysis MOS: 96B. Skill Levels 1 & 2.

    DTIC Science & Technology

    1981-05-01

    Level 1 PREPARED BY: OPERATIONS DIV, DPFO Coi - COPIES ATOP Oft ,, 109-1 ,.b S0 .ditims b. ,od ! lil I l liliU DISCLAIMER NOTICE THIS DOCUMENT IS BEST...FORT MOiROE, VIRGINIA 23651 DEC1 lie I .t,., , ..’ t-o" . _ . - ir \\ . " . ! .. * - ,,\\ . . . ’ . . . . . . ,, ,. ,. ~~4W. PREPARE - -.Y, OPERATIONSDIV...FURTHER -IGAPS 14 GARRISON 7 GENFRAL1 GEUC.RAPHIC 9 GIVE 1S GIVEN I GOVERNMENTI GRAVE GREASE I. GP 111 3 GROLP2 GROUPS 2 GliIIDANCE - I GUICE I GUIDES 2 Ho

  12. Effect of oak wood barrel capacity and utilization time on phenolic and sensorial profile evolution of an Encruzado white wine.

    PubMed

    Nunes, Paulo; Muxagata, Sara; Correia, Ana C; Nunes, Fernando M; Cosme, Fernanda; Jordão, António M

    2017-04-06

    Several studies have reported the influence of diverse winemaking technologies in white wine characteristics. However, the impact of the use of different oak wood barrel capacities and utilization time on the evolution of white wine phenolic content and sensorial characteristics are not usually considered. Thus the aim of this work was to evaluate the effect of oak wood barrel capacity and utilization time on the evolution of phenolic compounds, browning potential index and sensorial profile of an Encruzado white wine. For the 180 aging days considered, the use of new oak wood barrels induced a greater increase in global phenolic composition, including several individual compounds, such as gallic and ellagic acid, independently of the barrel capacity. Tendency for a lesser increase of the browning potential index values was detected for white wines aged in new oak wood barrels. The sensorial profile evolution, showed significant differences only for the aroma descriptors, namely for 'wood aroma' and 'aroma intensity', white wine aged in 225 L new oak wood barrels being the highest scored. The results show that, in general, the use of different capacities and utilization time of oak wood barrels used for white wine aging could play an important role in white wine quality. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  13. Consumer demand for green stormwater management technology in an urban setting: The case of Chicago rain barrels

    NASA Astrophysics Data System (ADS)

    Ando, Amy W.; Freitas, Luiz P. C.

    2011-12-01

    Hydrological disruption and water pollution from urbanization can be reduced if households in urban areas adopt decentralized storm water controls. We study a citywide municipal subsidized rain-barrel program in the third biggest city in the United States, Chicago, to explore what factors influence whether households purchase this sort of green storm water management technology in an urban setting. Specifically, we regress census-tract level data on the number of rain barrels adopted in different parts of the city on socioeconomic variables, data on local flood frequency, and features of the housing stock. We find that rain-barrel purchases are not correlated with local levels of flooding, even though city residents were told by program managers that rain barrels could alleviate local flooding. Instead, rain barrels are heavily concentrated in places with high-income attitudinally green populations. We do find more rain barrels were adopted in places close to rain-barrel distribution points and near sites of hydrological information campaigns; thus, policy makers might increase green-technology adoption in areas where they can do the most good by reducing transaction costs and providing education programs to those areas. Finally, our results indicate that owner occupancy is positively correlated with green-technology adoption. Low-rise rental housing may have inefficiently low levels of adoption, such that city managers might want to develop programs to encourage storm water management investments by landlords who do not live in their own properties.

  14. A Supercomplex Spanning the Inner and Outer Membranes Mediates the Biogenesis of β-Barrel Outer Membrane Proteins in Bacteria.

    PubMed

    Wang, Yan; Wang, Rui; Jin, Feng; Liu, Yang; Yu, Jiayu; Fu, Xinmiao; Chang, Zengyi

    2016-08-05

    β-barrel outer membrane proteins (OMPs) are ubiquitously present in Gram-negative bacteria, mitochondria and chloroplasts, and function in a variety of biological processes. The mechanism by which the hydrophobic nascent β-barrel OMPs are transported through the hydrophilic periplasmic space in bacterial cells remains elusive. Here, mainly via unnatural amino acid-mediated in vivo photo-crosslinking studies, we revealed that the primary periplasmic chaperone SurA interacts with nascent β-barrel OMPs largely via its N-domain but with β-barrel assembly machine protein BamA mainly via its satellite P2 domain, and that the nascent β-barrel OMPs interact with SurA via their N- and C-terminal regions. Additionally, via dual in vivo photo-crosslinking, we demonstrated the formation of a ternary complex involving β-barrel OMP, SurA, and BamA in cells. More importantly, we found that a supercomplex spanning the inner and outer membranes and involving the BamA, BamB, SurA, PpiD, SecY, SecE, and SecA proteins appears to exist in living cells, as revealed by a combined analyses of sucrose-gradient ultra-centrifugation, Blue native PAGE and mass spectrometry. We propose that this supercomplex integrates the translocation, transportation, and membrane insertion events for β-barrel OMP biogenesis. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  15. Cobalamin-Independent Methionine Synthase (MetE): A Face-to-Face Double Barrel that Evolved by Gene Duplication

    SciTech Connect

    Pejcha, Robert; Ludwig, Martha L.

    2010-03-08

    Cobalamin-independent methionine synthase (MetE) catalyzes the transfer of a methyl group from methyltetrahydrofolate to L-homocysteine (Hcy) without using an intermediate methyl carrier. Although MetE displays no detectable sequence homology with cobalamin-dependent methionine synthase (MetH), both enzymes require zinc for activation and binding of Hcy. Crystallographic analyses of MetE from T. maritima reveal an unusual dual-barrel structure in which the active site lies between the tops of the two ({beta}{alpha}){sub 8} barrels. The fold of the N-terminal barrel confirms that it has evolved from the C-terminal polypeptide by gene duplication; comparisons of the barrels provide an intriguing example of homologous domain evolution in which binding sites are obliterated. The C-terminal barrel incorporates the zinc ion that binds and activates Hcy. The zinc-binding site in MetE is distinguished from the (Cys){sub 3}Zn site in the related enzymes, MetH and betaine-homocysteine methyltransferase, by its position in the barrel and by the metal ligands, which are histidine, cysteine, glutamate, and cysteine in the resting form of MetE. Hcy associates at the face of the metal opposite glutamate, which moves away from the zinc in the binary E {center_dot} Hcy complex. The folate substrate is not intimately associated with the N-terminal barrel; instead, elements from both barrels contribute binding determinants in a binary complex in which the folate substrate is incorrectly oriented for methyl transfer. Atypical locations of the Hcy and folate sites in the C-terminal barrel presumably permit direct interaction of the substrates in a ternary complex. Structures of the binary substrate complexes imply that rearrangement of folate, perhaps accompanied by domain rearrangement, must occur before formation of a ternary complex that is competent for methyl transfer.

  16. The CMS Level-1 trigger system for LHC Run II

    NASA Astrophysics Data System (ADS)

    Cadamuro, L.

    2017-03-01

    The Compact Muon Solenoid (CMS) experiment implements a sophisticated two-level online selection system that achieves a rejection factor of nearly 105. During Run II, the LHC has increased the centre-of-mass energy of proton-proton collisions up to 13 TeV and may progressively reach an instantaneous luminosity of 2×1034 cm‑2 s‑1 or higher. In order to guarantee a successful and ambitious physics programme under this intense environment, the CMS Trigger and Data acquisition system has been upgraded. The upgraded CMS Level-1 (L1) trigger benefits from the recent μTCA technology and is designed to maintain the performance under high instantaneous luminosity conditions. More sophisticated, innovative algorithms are now the core of the first decision layer of CMS: this drastically reduces the trigger rate and improves the trigger efficiency for a wide variety of physics processes. In this document, we present the overall architecture of the upgraded Level-1 trigger system. The performance of single object triggers, measured on collision data recorded during the 2016 running period, are also summarised.

  17. The CMS Level-1 Calorimeter Trigger for LHC Run II

    NASA Astrophysics Data System (ADS)

    Sinthuprasith, Tutanon

    2017-01-01

    The phase-1 upgrades of the CMS Level-1 calorimeter trigger have been completed. The Level-1 trigger has been fully commissioned and it will be used by CMS to collect data starting from the 2016 data run. The new trigger has been designed to improve the performance at high luminosity and large number of simultaneous inelastic collisions per crossing (pile-up). For this purpose it uses a novel design, the Time Multiplexed Design, which enables the data from an event to be processed by a single trigger processor at full granularity over several bunch crossings. The TMT design is a modular design based on the uTCA standard. The architecture is flexible and the number of trigger processors can be expanded according to the physics needs of CMS. Intelligent, more complex, and innovative algorithms are now the core of the first decision layer of CMS: the upgraded trigger system implements pattern recognition and MVA (Boosted Decision Tree) regression techniques in the trigger processors for pT assignment, pile up subtraction, and isolation requirements for electrons, and taus. The performance of the TMT design and the latency measurements and the algorithm performance which has been measured using data is also presented here.

  18. System design and performances of ASTER Level-1 data processing

    NASA Astrophysics Data System (ADS)

    Nishida, Sumiyuki; Hachiya, Jun; Matsumoto, Ken; Fujisada, Hiroyuki; Kato, Masatane

    1998-12-01

    ASTER is a multispectral imager which covers wide spectral region from visible to thermal infrared with 14 spectral bands, and will fly on EOS-AM1 in 1999. To meet this wide spectral coverage, ASTER has three optical sensing subsystems (multi-telescope system), VNIR, SWIR and TIR. This multi- telescope configuration requires highly refined ground processing for the generation of Level-1 data products that are radiometrically calibrated and geometrically corrected. A prototype Level-1 processing software system is developed to satisfy these requirements. System design concept adopted includes; (1) 'Automatic Processing,' (2)'ALL-IN-ONE-CONCEPT' in which the processing is carried out using information included in Level-0 data product only, (3) 'MODULE INDEPENDENCE' in which only process control module independently control other modules to change any operational conditions. (4) 'FLEXIBILITY' in which important operation parameters are set from an external component to make the processing condition change easier. The adaptability and the performance of the developed software system are evaluated using simulation data.

  19. Upgrade of the ATLAS muon spectrometer for operation at the HL-LHC

    NASA Astrophysics Data System (ADS)

    Kortner, Oliver

    2017-02-01

    The High-Luminosity Large Hadron Collider will increase the sensitivity of the ATLAS experiment to rare physics processes. In order to cope with a 10 times higher instantaneous luminosity compared to the LHC, the trigger system of ATLAS needs to be upgraded. The ATLAS experiment plans to increase the maximum rate capability of the 1st trigger level to 1 MHz at 6 μ s latency. This requires new on- and off-chamber electronics for its muon spectrometer. The replacement of the precision chamber read-out electronics will make it possible to include their data in the 1st level trigger decision and thus to increase the selectivity of the 1st level muon trigger. The acceptance of the present RPC trigger system in the barrel region will be increased from 75% to 95% by the installation of additional thin-gap RPC with a substantially increased high-rate capability compared to the current RPCs.

  20. MODIS. Volume 2: MODIS level 1 geolocation, characterization and calibration algorithm theoretical basis document, version 1

    NASA Technical Reports Server (NTRS)

    Barker, John L.; Harnden, Joann M. K.; Montgomery, Harry; Anuta, Paul; Kvaran, Geir; Knight, ED; Bryant, Tom; Mckay, AL; Smid, Jon; Knowles, Dan, Jr.

    1994-01-01

    The EOS Moderate Resolution Imaging Spectrometer (MODIS) is being developed by NASA for flight on the Earth Observing System (EOS) series of satellites, the first of which (EOS-AM-1) is scheduled for launch in 1998. This document describes the algorithms and their theoretical basis for the MODIS Level 1B characterization, calibration, and geolocation algorithms which must produce radiometrically, spectrally, and spatially calibrated data with sufficient accuracy so that Global change research programs can detect minute changes in biogeophysical parameters. The document first describes the geolocation algorithm which determines geodetic latitude, longitude, and elevation of each MODIS pixel and the determination of geometric parameters for each observation (satellite zenith angle, satellite azimuth, range to the satellite, solar zenith angle, and solar azimuth). Next, the utilization of the MODIS onboard calibration sources, which consist of the Spectroradiometric Calibration Assembly (SRCA), Solar Diffuser (SD), Solar Diffuser Stability Monitor (SDSM), and the Blackbody (BB), is treated. Characterization of these sources and integration of measurements into the calibration process is described. Finally, the use of external sources, including the Moon, instrumented sites on the Earth (called vicarious calibration), and unsupervised normalization sites having invariant reflectance and emissive properties is treated. Finally, algorithms for generating utility masks needed for scene-based calibration are discussed. Eight appendices are provided, covering instrument design and additional algorithm details.

  1. Ion mobility spectrometer / mass spectrometer (IMS-MS).

    SciTech Connect

    Hunka Deborah Elaine; Austin, Daniel E.

    2005-07-01

    The use of Ion Mobility Spectrometry (IMS) in the Detection of Contraband Sandia researchers use ion mobility spectrometers for trace chemical detection and analysis in a variety of projects and applications. Products developed in recent years based on IMS-technology include explosives detection personnel portals, the Material Area Access (MAA) checkpoint of the future, an explosives detection vehicle portal, hand-held detection systems such as the Hound and Hound II (all 6400), micro-IMS sensors (1700), ordnance detection (2500), and Fourier Transform IMS technology (8700). The emphasis to date has been on explosives detection, but the detection of chemical agents has also been pursued (8100 and 6400). Combining Ion Mobility Spectrometry (IMS) with Mass Spectrometry (MS) is described. The IMS-MS combination overcomes several limitations present in simple IMS systems. Ion mobility alone is insufficient to identify an unknown chemical agent. Collision cross section, upon which mobility is based, is not sufficiently unique or predictable a priori to be able to make a confident peak assignment unless the compounds present are already identified. Molecular mass, on the other hand, is much more readily interpreted and related to compounds. For a given compound, the molecular mass can be determined using a pocket calculator (or in one's head) while a reasonable value of the cross-section might require hours of computation time. Thus a mass spectrum provides chemical specificity and identity not accessible in the mobility spectrum alone. In addition, several advanced mass spectrometric methods, such as tandem MS, have been extensively developed for the purpose of molecular identification. With an appropriate mass spectrometer connected to an ion mobility spectrometer, these advanced identification methods become available, providing greater characterization capability.

  2. Ion Mobility Spectrometer / Mass Spectrometer (IMS-MS).

    SciTech Connect

    Hunka, Deborah E; Austin, Daniel

    2005-10-01

    The use of Ion Mobility Spectrometry (IMS)in the Detection of Contraband Sandia researchers use ion mobility spectrometers for trace chemical detection and analysis in a variety of projects and applications. Products developed in recent years based on IMS-technology include explosives detection personnel portals, the Material Area Access (MAA) checkpoint of the future, an explosives detection vehicle portal, hand-held detection systems such as the Hound and Hound II (all 6400), micro-IMS sensors (1700), ordnance detection (2500), and Fourier Transform IMS technology (8700). The emphasis to date has been on explosives detection, but the detection of chemical agents has also been pursued (8100 and 6400).Combining Ion Mobility Spectrometry (IMS) with Mass Spectrometry (MS)The IMS-MS combination overcomes several limitations present in simple IMS systems. Ion mobility alone is insufficient to identify an unknown chemical agent. Collision cross section, upon which mobility is based, is not sufficiently unique or predictable a priori to be able to make a confident peak assignment unless the compounds present are already identified. Molecular mass, on the other hand, is much more readily interpreted and related to compounds. For a given compound, the molecular mass can be determined using a pocket calculator (or in one's head) while a reasonable value of the cross-section might require hours of computation time. Thus a mass spectrum provides chemical specificity and identity not accessible in the mobility spectrum alone. In addition, several advanced mass spectrometric methods, such as tandem MS, have been extensively developed for the purpose of molecular identification. With an appropriate mass spectrometer connected to an ion mobility spectrometer, these advanced identification methods become available, providing greater characterization capability.3 AcronymsIMSion mobility spectrometryMAAMaterial Access AreaMSmass spectrometryoaTOForthogonal acceleration time

  3. The FET1 Level 1 Method: Theory and Implementation

    SciTech Connect

    Kamath, C.

    2000-03-01

    This report summarizes our experiences in developing a prototype serial code for the implementation of the Level 1 Finite Element Tearing and Interconnecting (FETI) method. This method is a non-overlapping domain-decomposition scheme for the parallel solution of ill-conditioned systems of linear equations arising in structural mechanics problems. The FETI method has been shown to be numerically scalable for second order elasticity and fourth order plate and shell problems. In this report, we first outline the theory underlying the FETI method and discuss the approaches taken to improve the robustness and convergence of the method. We next provide implementation details, focusing on our serial prototype code. Finally, we present experimental results, followed by a summary of our observations.

  4. BOREAS AFM-5 Level-1 Upper Air Network Data

    NASA Technical Reports Server (NTRS)

    Barr, Alan; Hrynkiw, Charmaine; Newcomer, Jeffrey A. (Editor); Hall, Forrest G. (Editor); Smith, David E. (Technical Monitor)

    2000-01-01

    The Boreal Ecosystem-Atmosphere Study (BOREAS) Airborne Fluxes and Meteorology (AFM)-5 team collected and processed data from the numerous radiosonde flights during the project. The goals of the AFM-05 team were to provide large-scale definition of the atmosphere by supplementing the existing Atmospheric Environment Service (AES) aerological network, both temporally and spatially. This data set includes basic upper-air parameters collected from the network of upper-air stations during the 1993, 1994, and 1996 field campaigns over the entire study region. The data are contained in tabular ASCII files. The level-1 upper-air network data are available from the Earth Observing System Data and Information System (EOSDIS) Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC). The data files also are available on a CD-ROM (see document number 20010000884).

  5. ATLAS level-1 calorimeter trigger: Monitoring and data reprocessing

    NASA Astrophysics Data System (ADS)

    Dimond, David; Hong, Tae; Carlson, Benjamin; Atlas Collaboration

    2017-01-01

    We present the monitoring and data reprocessing for the calorimeter-based hardware level-1 trigger system (L1Calo) for the ATLAS experiment. This trigger system was upgraded after the Run-1 data taking period (2009-2012) to prepare for Run-2 (2015-current), which allowed better control the event rates for algorithms based on jets and/or missing energy. Monitoring tools for the upgraded system is described. We also present a new offline tool to reprocess previous data samples with altered L1Calo settings, such as calibration constants and noise cuts. The samples are used to study the dependence of the event rates and signal efficiencies on the settings. The studies can help plan the appropriate L1Calo settings for upcoming data taking periods as well as for future runs.

  6. Level1B Performance Evaluation On CryoSat Products

    NASA Astrophysics Data System (ADS)

    Scagliola, Michele; Fornari, Marco; Tagliani, Nicolas

    2013-12-01

    A performance assessment of the CryoSat products for SAR/SARin modes is here presented. The effective across-track IRF has been compared with the expected one, according to the system requirements, and exploiting the calibration products. Then, starting from the along-track processing for Delay/Doppler Radar altimeters, the theoretical model of the along-track IRF for CryoSat has been derived. Moreover the effects of the azimuth windowing on the along-track resolution and on the clutter suppression have been investigated. In particular, the clutter has been evaluated on the Level1b products for both sea ice and ocean scenario, revealing that the azimuth window allows to improve the signal to clutter ratio also in case of ocean waveforms.

  7. Whisker barrel cortex delta oscillations and gamma power in the awake mouse are linked to respiration

    PubMed Central

    Ito, J.; Roy, S.; Liu, Y.; Cao, Y.; Fletcher, M.; Lu, L.; Boughter, J.D.; Grün, S.; Heck, D.H.

    2014-01-01

    Current evidence suggests that delta oscillations (0.5–4 Hz) in the brain are generated by intrinsic network mechanisms involving cortical and thalamic circuits. Here we report that delta band oscillation in spike and local field potential (LFP) activity in the whisker barrel cortex of awake mice is phase locked to respiration. Furthermore, LFP oscillations in the gamma frequency band (30–80 Hz) are amplitude modulated in phase with the respiratory rhythm. Removal of the olfactory bulb eliminates respiration-locked delta oscillations and delta-gamma phase-amplitude coupling. Our findings thus suggest respiration-locked olfactory bulb activity as a main driving force behind delta oscillations and gamma power modulation in the whisker barrel cortex in the awake state. PMID:24686563

  8. Gamma ray scanner systems for nondestructive assay of heterogeneous waste barrels

    SciTech Connect

    Martz, H.E.; Roberson, G.P.; Decman, D.J.; Camp, D.C.; Levai, F.

    1997-08-01

    Traditional gamma measurement errors are related to non-uniform measurement responses associated with unknown radioactive source and matrix material distributions. These errors can be reduced by application of tomographic techniques that measure these distributions. LLNL has developed two tomographic-based waste assay systems. They use external radioactive sources and tomography-protocol to map the attenuation within a waste barrel as a function of mono-energetic gamma-ray energy in waste containers. Passive tomography is used to localize and identify specific radioactive waste contents within the same waste containers. Reconstruction of the passive data via the active images allows internal waste radioactivities in a barrel to be corrected for any overlying heterogeneous materials, thus yielding an absolute assay of the waste radioactivities. Calibration of both systems requires only point source measurements and are independent of matrix materials.

  9. Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints

    PubMed Central

    Chan, Yvonne H.; Venev, Sergey V.; Zeldovich, Konstantin B.; Matthews, C. Robert

    2017-01-01

    Sequence divergence of orthologous proteins enables adaptation to environmental stresses and promotes evolution of novel functions. Limits on evolution imposed by constraints on sequence and structure were explored using a model TIM barrel protein, indole-3-glycerol phosphate synthase (IGPS). Fitness effects of point mutations in three phylogenetically divergent IGPS proteins during adaptation to temperature stress were probed by auxotrophic complementation of yeast with prokaryotic, thermophilic IGPS. Analysis of beneficial mutations pointed to an unexpected, long-range allosteric pathway towards the active site of the protein. Significant correlations between the fitness landscapes of distant orthologues implicate both sequence and structure as primary forces in defining the TIM barrel fitness landscape and suggest that fitness landscapes can be translocated in sequence space. Exploration of fitness landscapes in the context of a protein fold provides a strategy for elucidating the sequence-structure-fitness relationships in other common motifs. PMID:28262665

  10. Site geotechnical considerations for expansion of the Strategic Petroleum Reserve (SPR) to one billion barrels

    SciTech Connect

    Neal, J.T. ); Whittington, D.W. ); Magorian, T.R. , Amherst, NY )

    1991-01-01

    Eight Gulf Coast salt domes have emerged as candidate sites for possible expansion of the Strategic Petroleum Reserve (SPR) to one billion barrels. Two existing SPR sites, Big Hill, TX, and Weeks Island, LA, are among the eight that are being considered. To achieve the billion barrel capacity, some 25 new leached caverns would be constructed, and would probably be established in two separate sites in Louisiana and Texas because of distribution requirements. Geotechnical factors involved in siting studies have centered first and foremost on cavern integrity and environmental acceptability, once logistical suitability is realized. Other factors have involved subsidence and flooding potential, loss of coastal marshlands, seismicity, brine injection well utility, and co-use by multiple operators. 5 refs., 11 figs., 2 tabs.

  11. Results from the USIP_UH contribution to the BARREL-4 campaign

    NASA Astrophysics Data System (ADS)

    Behrend, C. C.; Bering, E. A., III; Ehteshami, A.; Fenton, A.; Gamblin, R.; Greer, M.; Mathur, S.; Glennie, C. L.; Velasquez, B.; Marpaung, J.; Lalata, M. C.

    2016-12-01

    The Undergraduate Student Instrumentation Project (USIP) at the University of Houston sent a team to Kiruna, Sweden to participate with NASA/Dartmouth's BARREL-4 campaign in August 2016. BARREL-4's primary instrument is an MeV x-ray scintillation counter. The team has provided two different experiments to be flown, a dual frequency GPS receiver to calculate total electron content and a Very Low Frequency (VLF) receiver to measure the VLF emissions associated with electron precipitation. TEC is calculated via finding pseudo-ranges comparing the sent and received signals from passing satellites. The VLF receiver has an air-core magnetic loop antenna that utilizes a transformer coupled with an integrating pre-amp which is then recorded to a standard music recorder. The presentation will include a summary of observations.

  12. a Barrel Ifr Instrumented with Limited Streamer Tubes for Babar Experiment

    NASA Astrophysics Data System (ADS)

    Cibinetto, Gianluigi

    The new barrel Instrumented Flux Return (IFR) of BABAR detector will be reported here. Limited Stramer Tubes (LSTs) have been chosen to replace the existing RPCs as active elements of the barrel IFR. The layout of the new detector will be discussed: in particular, a cell bigger than the standard one has been used to improve efficiency and reliability. The extruded profile is coated with a resistive layer of graphite having a typical surface resistivity between 0.2 and 0.4 MOhm/square. The tubes are assembled in modules and installed in 12 active layers of each sextant of the IFR detector. R&D studies which have been done to choose the final design will be discussed, as well as the Quality Control procedure adopted during the tube production to assure high performances of the detector.

  13. A Barrel IFR Instrumented With Limited Streamer Tubes for BABAR Experiment

    SciTech Connect

    Andreotti, M.; /Ferrara U. /INFN, Ferrara

    2006-11-15

    The new barrel Instrumented Flux Return (IFR) of BABAR detector will be reported here. Limited Streamer Tubes (LSTs) have been chosen to replace the existing RPCs as active elements of the barrel IFR. The layout of the new detector will be discussed: in particular, a cell bigger than the standard one has been used to improve efficiency and reliability. The extruded profile is coated with a resistive layer of graphite having a typical surface resistivity between 0.2 and 0.4 MOhm/square. The tubes are assembled in modules and installed in 12 active layers of each sextant of the IFR detector. R&D studies to choose the final design and Quality Control procedure adopted during the tube production will be briefly discussed. Finally the performances of installed LSTs into 2/3 of IFR after 8 months of operations will be reported.

  14. a Barrel Ifr Instrumented with Limited Streamer Tubes for Babar Experiment

    NASA Astrophysics Data System (ADS)

    Andreotti, Mirco

    2006-04-01

    The new barrel Instrumented Flux Return (IFR) of BABAR detector will be reported here. Limited Streamer Tubes (LSTs) have been chosen to replace the existing RPCs as active elements of the barrel IFR. The layout of the new detector will be discussed: in particular, a cell bigger than the standard one has been used to improve efficiency and reliability. The extruded profile is coated with a resistive layer of graphite having a typical surface resistivity between 0.2 and 0.4 MOhm/square. The tubes are assembled in modules and installed in 12 active layers of each sextant of the IFR detector. R&D studies to choose the final design and Quality Control procedure adopted during the tube production will be briefly discussed. Finally the performances of installed LSTs into 2/3 of IFR after 8 months of operations will be reported.

  15. Synaptic molecular imaging in spared and deprived columns of mouse barrel cortex with array tomography

    PubMed Central

    Weiler, Nicholas C; Collman, Forrest; Vogelstein, Joshua T; Burns, Randal; Smith, Stephen J

    2014-01-01

    A major question in neuroscience is how diverse subsets of synaptic connections in neural circuits are affected by experience dependent plasticity to form the basis for behavioral learning and memory. Differences in protein expression patterns at individual synapses could constitute a key to understanding both synaptic diversity and the effects of plasticity at different synapse populations. Our approach to this question leverages the immunohistochemical multiplexing capability of array tomography (ATomo) and the columnar organization of mouse barrel cortex to create a dataset comprising high resolution volumetric images of spared and deprived cortical whisker barrels stained for over a dozen synaptic molecules each. These dataset has been made available through the Open Connectome Project for interactive online viewing, and may also be downloaded for offline analysis using web, Matlab, and other interfaces. PMID:25977797

  16. Synaptic molecular imaging in spared and deprived columns of mouse barrel cortex with array tomography.

    PubMed

    Weiler, Nicholas C; Collman, Forrest; Vogelstein, Joshua T; Burns, Randal; Smith, Stephen J

    2014-01-01

    A major question in neuroscience is how diverse subsets of synaptic connections in neural circuits are affected by experience dependent plasticity to form the basis for behavioral learning and memory. Differences in protein expression patterns at individual synapses could constitute a key to understanding both synaptic diversity and the effects of plasticity at different synapse populations. Our approach to this question leverages the immunohistochemical multiplexing capability of array tomography (ATomo) and the columnar organization of mouse barrel cortex to create a dataset comprising high resolution volumetric images of spared and deprived cortical whisker barrels stained for over a dozen synaptic molecules each. These dataset has been made available through the Open Connectome Project for interactive online viewing, and may also be downloaded for offline analysis using web, Matlab, and other interfaces.

  17. Operation of the Upgraded ATLAS Level-1 Central Trigger System

    NASA Astrophysics Data System (ADS)

    Glatzer, Julian

    2015-12-01

    The ATLAS Level-1 Central Trigger (L1CT) system is a central part of ATLAS data-taking and has undergone a major upgrade for Run 2 of the LHC, in order to cope with the expected increase of instantaneous luminosity of a factor of two with respect to Run 1. The upgraded hardware offers more flexibility in the trigger decisions due to the factor of two increase in the number of trigger inputs and usable trigger channels. It also provides an interface to the new topological trigger system. Operationally - particularly useful for commissioning, calibration and test runs - it allows concurrent running of up to three different subdetector combinations. An overview of the operational software framework of the L1CT system with particular emphasis on the configuration, controls and monitoring aspects is given. The software framework allows a consistent configuration with respect to the ATLAS experiment and the LHC machine, upstream and downstream trigger processors, and the data acquisition system. Trigger and dead-time rates are monitored coherently at all stages of processing and are logged by the online computing system for physics analysis, data quality assurance and operational debugging. In addition, the synchronisation of trigger inputs is watched based on bunch-by-bunch trigger information. Several software tools allow for efficient display of the relevant information in the control room in a way useful for shifters and experts. The design of the framework aims at reliability, flexibility, and robustness of the system and takes into account the operational experience gained during Run 1. The Level-1 Central Trigger was successfully operated with high efficiency during the cosmic-ray, beam-splash and first Run 2 data taking with the full ATLAS detector.

  18. Parallel beta/alpha-barrels of alpha-amylase, cyclodextrin glycosyltransferase and oligo-1,6-glucosidase versus the barrel of beta-amylase: evolutionary distance is a reflection of unrelated sequences.

    PubMed

    Janecek, S

    1994-10-17

    The structures of functionally related beta/alpha-barrel starch hydrolases, alpha-amylase, beta-amylase, cyclodextrin glycosyltransferase and oligo-1,6-glucosidase, are discussed, their mutual sequence similarities being emphasized. Since these enzymes (except for beta-amylase) along with the predicted set of more than ten beta/alpha-barrels from the alpha-amylase enzyme superfamily fulfil the criteria characteristic of the products of divergent evolution, their unrooted distance tree is presented.

  19. Cofilin1 Controls Transcolumnar Plasticity in Dendritic Spines in Adult Barrel Cortex

    PubMed Central

    Tsubota, Tadashi; Okubo-Suzuki, Reiko; Ohashi, Yohei; Tamura, Keita; Ogata, Koshin; Yaguchi, Masae; Matsuyama, Makoto; Inokuchi, Kaoru; Miyashita, Yasushi

    2015-01-01

    During sensory deprivation, the barrel cortex undergoes expansion of a functional column representing spared inputs (spared column), into the neighboring deprived columns (representing deprived inputs) which are in turn shrunk. As a result, the neurons in a deprived column simultaneously increase and decrease their responses to spared and deprived inputs, respectively. Previous studies revealed that dendritic spines are remodeled during this barrel map plasticity. Because cofilin1, a predominant regulator of actin filament turnover, governs both the expansion and shrinkage of the dendritic spine structure in vitro, it hypothetically regulates both responses in barrel map plasticity. However, this hypothesis remains untested. Using lentiviral vectors, we knocked down cofilin1 locally within layer 2/3 neurons in a deprived column. Cofilin1-knocked-down neurons were optogenetically labeled using channelrhodopsin-2, and electrophysiological recordings were targeted to these knocked-down neurons. We showed that cofilin1 knockdown impaired response increases to spared inputs but preserved response decreases to deprived inputs, indicating that cofilin1 dependency is dissociated in these two types of barrel map plasticity. To explore the structural basis of this dissociation, we then analyzed spine densities on deprived column dendritic branches, which were supposed to receive dense horizontal transcolumnar projections from the spared column. We found that spine number increased in a cofilin1-dependent manner selectively in the distal part of the supragranular layer, where most of the transcolumnar projections existed. Our findings suggest that cofilin1-mediated actin dynamics regulate functional map plasticity in an input-specific manner through the dendritic spine remodeling that occurs in the horizontal transcolumnar circuits. These new mechanistic insights into transcolumnar plasticity in adult rats may have a general significance for understanding reorganization of

  20. Nitrobindin: An Ubiquitous Family of All β-Barrel Heme-proteins.

    PubMed

    De Simone, Giovanna; Ascenzi, Paolo; Polticelli, Fabio

    2016-06-01

    Rhodnius prolixus nitrophorins (Rp-NPs), Arabidopsis thaliana nitrobindin (At-Nb), and Homo sapiens THAP4 (Hs-THAP4) are the unique known proteins that use a β-barrel fold to bind ferric heme, which is devoted to NO transport and/or catalysis. The eight-stranded antiparallel β-barrel Rp-NPs, which represent the only heme-binding lipocalins, are devoted to deliver NO into the blood vessel of the host and to scavenge histamine during blood sucking. Regarding Nbs, crystallographic data suggest the ability of At-Nb and Hs-THAP4 to bind ferric heme; however, no data are available with respect to these functions in the natural host. Here, a bioinformatics investigation based on the amino acid sequences and three-dimensional structures of At-Nb and Hs-THAP4 suggests a conservation of the 10-stranded antiparallel β-barrel Nb structural module in all life kingdoms of the evolutionary ladder. In particular, amino acid residues involved in the heme recognition and in the structure stabilization of the Nb structural module are highly conserved (identity > 29%; homology > 83%). Moreover, molecular models of putative Nbs from different organisms match very well with each other and known three-dimensional structures of Nbs. Furthermore, phylogenetic tree reconstruction indicates that NPs and Nbs group in distinct clades. These data indicate that 10-stranded β-barrel Nbs constitute a new ubiquitous heme protein family spanning from bacteria to Homo sapiens. © 2016 IUBMB Life, 68(6):423-428, 2016.

  1. Fabrication and Tests of M240 Machine Gun Barrels Lined with Stellite 25

    DTIC Science & Technology

    2016-04-01

    ARL-TR-7662 ● APR 2016 US Army Research Laboratory Fabrication and Tests of M240 Machine Gun Barrels Lined with Stellite 25...report when it is no longer needed. Do not return it to the originator. ARL-TR-7662 ● APR 2016 US Army Research Laboratory ...UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) US Army Research Laboratory ATTN: RDRL-WMM-F Aberdeen Proving Ground, MD 21005

  2. Particle contamination from Martin Optical Black. [in design of barrel baffle of Infrared Astronomical Satellite

    NASA Technical Reports Server (NTRS)

    Young, P. J.; Noll, R.; Andreozzi, L.; Hope, J.

    1981-01-01

    The design of the barrel baffle of the Infrared Astronomical Satellite (IRAS) Optical Subsystem to minimize production of particulate contamination is described. The configuration of the 50-inch long, 28.5-inch diameter baffle required pop-rivet assembly after coating with Martin Optical Black for stray light suppression. An experiment to determine the contamination produced at assembly led to the modification of the baffle construction to preclude such damage to the coated surfaces.

  3. A 30degree 'barrel shot' taken at track level showing operator's ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A 30-degree 'barrel shot' taken at track level showing operator's house in center of swing span and the track with timber ties. The ties are transverse (90-degree) to the track with each end resting on the bottom chord of the steel swing span truss, thus providing their support with live loads being transferred to the swing span truss bridge. - Bridgeport Swing Span Bridge, Spanning Tennessee River, Bridgeport, Jackson County, AL

  4. Double-barreled and Concentric Microelectrodes for Measurement of Extracellular Ion Signals in Brain Tissue

    PubMed Central

    Haack, Nicole; Durry, Simone; Kafitz, Karl W.; Chesler, Mitchell; Rose, Christine R.

    2015-01-01

    Electrical activity in the brain is accompanied by significant ion fluxes across membranes, resulting in complex changes in the extracellular concentration of all major ions. As these ion shifts bear significant functional consequences, their quantitative determination is often required to understand the function and dysfunction of neural networks under physiological and pathophysiological conditions. In the present study, we demonstrate the fabrication and calibration of double-barreled ion-selective microelectrodes, which have proven to be excellent tools for such measurements in brain tissue. Moreover, so-called “concentric” ion-selective microelectrodes are also described, which, based on their different design, offer a far better temporal resolution of fast ion changes. We then show how these electrodes can be employed in acute brain slice preparations of the mouse hippocampus. Using double-barreled, potassium-selective microelectrodes, changes in the extracellular potassium concentration ([K+]o) in response to exogenous application of glutamate receptor agonists or during epileptiform activity are demonstrated. Furthermore, we illustrate the response characteristics of sodium-sensitive, double-barreled and concentric electrodes and compare their detection of changes in the extracellular sodium concentration ([Na+]o) evoked by bath or pressure application of drugs. These measurements show that while response amplitudes are similar, the concentric sodium microelectrodes display a superior signal-to-noise ratio and response time as compared to the double-barreled design. Generally, the demonstrated procedures will be easily transferable to measurement of other ions species, including pH or calcium, and will also be applicable to other preparations. PMID:26381747

  5. Particle contamination from Martin Optical Black. [in design of barrel baffle of Infrared Astronomical Satellite

    NASA Technical Reports Server (NTRS)

    Young, P. J.; Noll, R.; Andreozzi, L.; Hope, J.

    1981-01-01

    The design of the barrel baffle of the Infrared Astronomical Satellite (IRAS) Optical Subsystem to minimize production of particulate contamination is described. The configuration of the 50-inch long, 28.5-inch diameter baffle required pop-rivet assembly after coating with Martin Optical Black for stray light suppression. An experiment to determine the contamination produced at assembly led to the modification of the baffle construction to preclude such damage to the coated surfaces.

  6. Altered somatosensory barrel cortex refinement in the developing brain of Mecp2-null mice.

    PubMed

    Moroto, M; Nishimura, A; Morimoto, M; Isoda, K; Morita, T; Yoshida, M; Morioka, S; Tozawa, T; Hasegawa, T; Chiyonobu, T; Yoshimoto, K; Hosoi, H

    2013-11-06

    Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the methyl-CpG binding protein 2 (MeCP2) gene. In previous studies, monoaminergic dysfunctions have been detected in patients with RTT and in a murine model of RTT, the Mecp2-null mouse. Therefore, the pathogenesis of RTT is thought to involve impairments in the monoaminergic systems. However, there have been limited data showing that the impairment of monoamines leads to early symptoms during development. We used histochemistry to study the somatosensory barrel cortex in the B6.129P2(C)-Mecp2(tm1.1Bird) mouse model of RTT. The barrel cortex is widely used to investigate neuronal development and its regulation by various neurotransmitters including 5-HT. 5-HT levels were measured by high performance liquid chromatography with electrochemical detection (HPLC/EC), and serotonin transporter (SERT) and 5-HT1B receptor mRNAs were measured in the somatosensory cortex, thalamus and striatum on postnatal days (P) 10, P20 and P40. Mecp2-null mice (Mecp2-/y) had significantly smaller barrel fields than age-matched wild-type controls (Mecp2+/y) on P10 and P40, but the topographic map was accurately formed. Levels of 5-HT, and SERT and 5-HT1B receptor mRNA expression in the somatosensory cortex did not differ significantly between the Mecp2-null and wild-type mice on P10. However, thalamic 5-HT was reduced in Mecp2-null mice. Our data indicate that a lack of MeCP2 may disturb the refinement of the barrel cortex in the early postnatal period. Our findings suggest that a decrease in thalamic 5-HT might be involved in this phenomenon.

  7. BARREL observations of a solar energetic electron and solar energetic proton event

    NASA Astrophysics Data System (ADS)

    Halford, A. J.; McGregor, S. L.; Hudson, M. K.; Millan, R. M.; Kress, B. T.

    2016-05-01

    During the second Balloon Array for Radiation Belt Relativistic Electron Losses (BARREL) campaign two solar energetic proton (SEP) events were observed. Although BARREL was designed to observe X-rays created during electron precipitation events, it is sensitive to X-rays from other sources. The gamma lines produced when energetic protons hit the upper atmosphere are used in this paper to study SEP events. During the second SEP event starting on 7 January 2014 and lasting ˜3 days, which also had a solar energetic electron (SEE) event occurring simultaneously, BARREL had six payloads afloat spanning all magnetic local time (MLT) sectors and L values. Three payloads were in a tight array (˜2 h in MLT and ˜2 ΔL) inside the inner magnetosphere and at times conjugate in both L and MLT with the Van Allen Probes (approximately once per day). The other three payloads mapped to higher L values with one payload on open field lines for the entire event, while the other two appear to be crossing from open to closed field lines. Using the observations of the SEE and SEP events, we are able to map the open-closed boundary. Halford et al. (2015) demonstrated how BARREL can monitor electron precipitation following an interplanetary shock created by a coronal mass ejection (ICME-shock) arrival at Earth, while in this study we look at the SEP event precursor to the arrival of the ICME-Shock in our cradle-to-grave view: from flare, to SEE and SEP events, to radiation belt electron precipitation.

  8. Double-barreled wet colostomy: a safe and simple method after pelvic exenteration.

    PubMed

    Osorio Gullón, A; de Oca, J; Lopéz Costea, M A; Virgili, J; Ramos, E; del Rio, C; Martí Ragué, J

    1997-01-01

    The clinical and functional outcome of ureteric division to the distal segment of a loop colostomy: the double-barrelled wet colostomy have been analysed. 13 patients (8 female and 5 male, age 37 to 72 years) underwent pelvic exenteration with double-barrelled wet colostomy. The primary tumour included endometrial (n = 6), rectal (n = 1), anal (n = 1), cervical (n = 2), prostatic (n = 1) and bladder (n = 2). Indications for pelvic exenteration were locally advanced disease, recurrence and severe radiation or surgical damage. Six patients had pre-existing colostomy, and three had a Bricker ureteroileal diversion. The double-barrelled-wet colostomy technique consisted in anastomosing both ureters to a colon segment 25 cm distal to the loop colostomy. There was no operative mortality. Complications included one urinary leak which closed with conservative management and one case of recurrent episodes of pyelonephritis which finally required nephrectomy. Intravenous urography in the remaining patients showed good flow through the ureters to the conduit with no reflux. Postoperative plasma electrolytes, urea and creatinine were normal from day seven onwards. Urodynamic studies in four patients showed efficient contraction of the colon conduit with pressure levels similar to those in the colon proximal to the colostomy. In five cases biopsies of the conduit were taken at 3 and 16 months; no dysplasias were found. Four patients died due to disease progression. The overall mean survival was 41.2 months. The remainder are currently disease-free, maximum followup period being 19 months. Double-barrelled wet colostomy is a safe and simple technique with low morbidity. The patient needs to carry only one stoma and functional results are good.

  9. Spatiotemporal evolution of excitation and inhibition in the rat barrel cortex investigated with multielectrode arrays.

    PubMed

    Wirth, Corina; Lüscher, Hans-R

    2004-04-01

    We investigated the spatiotemporal evolution of activity in the rat barrel cortex using multielectrode arrays (MEAs). In acute brain slices, field potentials were recorded simultaneously from 60 electrodes with high spatial and temporal resolution. This new technique allowed us to map functionally discrete barrels and to observe the interplay between the excitatory and inhibitory network. The local field potentials (LFPs) were elicited by focal electrical stimulation in layer 4 (L4). Excitation recorded in a single barrel was first confined to the stimulated barrel and subsequently spread in a columnar manner to layer 2/3 (L2/3). This excitation in L4 and lower L2/3 was followed by inhibition curtailing excitation to a short period lasting only approximately 2 ms. In the uppermost layer, a long-lasting (approximately 10 ms), laterally spreading band of excitation remained active. Blockade of GABAA-receptors resulted in a long-lasting and diffuse activation of L4 and lower L2/3 and abolition of activation of the upper L2/3. Thus inhibition not only shaped the spatial-temporal map of excitation in L4 and lower L2/3 but also resulted indirectly in an excitatory action in the superficial layers. Stimulation in L6 revealed a feedforward inhibition to L4 and subsequently an excitatory L6-L4-L6 loop. The complex interplay between excitation and inhibition opens two spatial windows of excitation in the infra- and supragranular layers. They may prepare the L5 pyramidal neuron for associating top-down input from other cortical regions with bottom-up input from the whisker pad to generate behaviorally relevant output.

  10. The Fabrication and Testing of Glass Matrix Composite Cylinders for Gun Barrel Liner Applications

    DTIC Science & Technology

    1982-02-01

    completely seal the com- posite from the HIP gas environment. Metal HIP Containers - The use of a stainless steel metal envelope is another approach to...catastrophic failure was exhibited. INTRODUCTION AND BACKGROUND Current state-of-the-art gun barrels are fabricated from stellite lined chrome...plated steel tubes. Due to their high percentage of the critical ele- ments cobalt and chromium, they are becoming increasingly expensive to manu

  11. Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins.

    PubMed

    Romero-Romero, Sergio; Costas, Miguel; Rodríguez-Romero, Adela; Alejandro Fernández-Velasco, D

    2015-08-28

    Temperature is one of the main variables that modulate protein function and stability. Thermodynamic studies of oligomeric proteins, the dominant protein natural form, have been often hampered because irreversible aggregation and/or slow reactions are common. There are no reports on the reversible equilibrium thermal unfolding of proteins composed of (β/α)8 barrel subunits, albeit this "TIM barrel" topology is one of the most abundant and versatile in nature. We studied the eponymous TIM barrel, triosephosphate isomerase (TIM), belonging to five species of different bacterial taxa. All of them were found to be catalytically efficient dimers. The three-dimensional structure of four enzymes was solved at high/medium resolution. Irreversibility and kinetic control were observed in the thermal unfolding of two TIMs, while for the other three the thermal unfolding was found to follow a two-state equilibrium reversible process. Shifts in the global stability curves of these three proteins are related to the organismal temperature range of optimal growth and modulated by variations in maximum stability temperature and in the enthalpy change at that temperature. Reversibility appears to correlate with the low isoelectric point, the absence of a residual structure in the unfolded state, small cavity volume in the native state, low conformational stability and a low melting temperature. Furthermore, the strong coupling between dimer dissociation and monomer unfolding may reduce aggregation and favour reversibility. It is therefore very thought-provoking to find that a common topological ensemble, such as the TIM barrel, can unfold/refold in the Anfinsen way, i.e. without the help of the cellular machinery.

  12. The Pickup Ion Composition Spectrometer

    NASA Astrophysics Data System (ADS)

    Gilbert, Jason A.; Zurbuchen, Thomas H.; Battel, Steven

    2016-06-01

    Observations of newly ionized atoms that are picked up by the magnetic field in the expanding solar wind contain crucial information about the gas or dust compositions of their origins. The pickup ions (PUIs) are collected by plasma mass spectrometers and analyzed for their density, composition, and velocity distribution. In addition to measurements of PUIs from planetary sources, in situ measurements of interstellar gas have been made possible by spectrometers capable of differentiating between heavy ions of solar and interstellar origin. While important research has been done on these often singly charged ions, the instruments that have detected many of them were designed for the energy range and ionic charge states of the solar wind and energized particle populations, and not for pickup ions. An instrument optimized for the complete energy and time-of-flight characterization of pickup ions will unlock a wealth of data on these hitherto unobserved or unresolved PUI species. The Pickup Ion Composition Spectrometer (PICSpec) is one such instrument and can enable the next generation of pickup ion and isotopic mass composition measurements. By combining a large-gap time-of-flight-energy sensor with a -100 kV high-voltage power supply for ion acceleration, PUIs will not only be above the detection threshold of traditional solid-state energy detectors but also be resolved sufficiently in time of flight that isotopic composition can be determined. This technology will lead to a new generation of space composition instruments, optimized for measurements of both heliospheric and planetary pickup ions.

  13. Effects of sensory deprivation on columnar organization of neuronal circuits in the rat barrel cortex.

    PubMed

    Schierloh, Anja; Eder, Matthias; Zieglgänsberger, Walter; Dodt, Hans-Ulrich

    2004-08-01

    We examined whether sensory deprivation during formation of the cortical circuitry influences the pattern of intracortical single-cell connections in rat barrel cortex. Excitatory postsynaptic potentials (EPSPs) from layer 2/3 (L2/3) pyramidal neurons were recorded in vitro using patch-clamp techniques. In order to evoke EPSPs, presynaptic neurons were stimulated by photolytically applied glutamate, thus generating action potentials. Synaptic connections between the stimulated and the recorded neuron were identified by the occurrence of PSPs following photostimulation. Sensory deprivation changed the pattern of projections from L4 and L2/3 neurons to L2/3 pyramidal cells. In slices of non-deprived rats 86% of the total presynaptic neurons were located in the first and only 10% in the second barrel column. Deprivation changed these values to 67% and 26%, respectively. Therefore, the probability of presynaptic cells projecting to L2/3 neurons was shifted from adjacent to more remote barrel columns. These results indicate that deprivation of sensory input influences the pattern of intracortical connections.

  14. Destiny of a drop on a fiber: from barrel to clamshell and back

    NASA Astrophysics Data System (ADS)

    Eral, Burak; de Ruiter, J.; de Ruiter, R.; Oh, J. M.; Semprebon, C.; Brinkman, M.; Mugele, F.

    2011-11-01

    Drops on cylindrical fibers are a familiar sight, for instance in the form of dew drops on spider webs. They can exist in two competing morphologies, a cylindrically symmetric barrel state completely engulfing the fiber and an asymmetric clamshell state, in which the drop sits on the side of the fiber. Despite their omnipresence and their practical relevance the physical mechanisms governing the stability of the two morphologies remained elusive. Using electrowetting-functionalized fibers we determined of the stability limits of both morphologies as a function of the two relevant control parameters, the contact angle and the liquid volume. While clamshells are found to prevail for large contact angles and small volumes, and barrels prevail for small angles and large volumes, there is also a wide range of intermediate parameter values, for which both morphologies are mechanically stable. Mapping out the energy landscape of the system by numerical minimization of the free energy we find that the barrel state is easily deformed by non-axisymmetric perturbations. From a general perspective, the demonstration of electrowetting-based reversible switching of liquid morphologies on fibers opens up opportunities for designing functional textiles and porous materials. We thank the Chemical Sciences division of the Netherlands Organization for Scientific Research (NWO-CW) for financial support.

  15. CREB Regulates Experience-Dependent Spine Formation and Enlargement in Mouse Barrel Cortex

    PubMed Central

    Pignataro, Annabella; Borreca, Antonella; Ammassari-Teule, Martine; Middei, Silvia

    2015-01-01

    Experience modifies synaptic connectivity through processes that involve dendritic spine rearrangements in neuronal circuits. Although cAMP response element binding protein (CREB) has a key function in spines changes, its role in activity-dependent rearrangements in brain regions of rodents interacting with the surrounding environment has received little attention so far. Here we studied the effects of vibrissae trimming, a widely used model of sensory deprivation-induced cortical plasticity, on processes associated with dendritic spine rearrangements in the barrel cortex of a transgenic mouse model of CREB downregulation (mCREB mice). We found that sensory deprivation through prolonged whisker trimming leads to an increased number of thin spines in the layer V of related barrel cortex (Contra) in wild type but not mCREB mice. In the barrel field controlling spared whiskers (Ipsi), the same trimming protocol results in a CREB-dependent enlargement of dendritic spines. Last, we demonstrated that CREB regulates structural rearrangements of synapses that associate with dynamic changes of dendritic spines. Our findings suggest that CREB plays a key role in dendritic spine dynamics and synaptic circuits rearrangements that account for new brain connectivity in response to changes in the environment. PMID:26075101

  16. Orofacial Neuropathic Pain Leads to a Hyporesponsive Barrel Cortex with Enhanced Structural Synaptic Plasticity

    PubMed Central

    Thibault, Karine; Rivière, Sébastien; Lenkei, Zsolt

    2016-01-01

    Chronic pain is a long-lasting debilitating condition that is particularly difficult to treat due to the lack of identified underlying mechanisms. Although several key contributing processes have been described at the level of the spinal cord, very few studies have investigated the supraspinal mechanisms underlying chronic pain. Using a combination of approaches (cortical intrinsic imaging, immunohistochemical and behavioural analysis), our study aimed to decipher the nature of functional and structural changes in a mouse model of orofacial neuropathic pain, focusing on cortical areas involved in various pain components. Our results show that chronic neuropathic orofacial pain is associated with decreased haemodynamic responsiveness to whisker stimulation in the barrel field cortex. This reduced functional activation is likely due to the increased basal neuronal activity (measured indirectly using cFos and phospho-ERK immunoreactivity) observed in several cortical areas, including the contralateral barrel field, motor and cingulate cortices. In the same animals, immunohistochemical analysis of markers for active pre- or postsynaptic elements (Piccolo and phospho-Cofilin, respectively) revealed an increased immunofluorescence in deep cortical layers of the contralateral barrel field, motor and cingulate cortices. These results suggest that long-lasting orofacial neuropathic pain is associated with exacerbated neuronal activity and synaptic plasticity at the cortical level. PMID:27548330

  17. Early bilateral sensory deprivation blocks the development of coincident discharge in rat barrel cortex.

    PubMed

    Ghoshal, Ayan; Pouget, Pierre; Popescu, Maria; Ebner, Ford

    2009-02-25

    Several theories have proposed a functional role for synchronous neuronal firing in generating the neural code of a sensory perception. Synchronous neural activity develops during a critical postnatal period of cortical maturation, and severely reducing neural activity in a sensory pathway during this period could interfere with the development of coincident discharge among cortical neurons. Loss of such synchrony could provide a fundamental mechanism for the degradation of acuity shown in behavioral studies. We tested the hypothesis that synchronous discharge of barrel cortex neurons would fail to develop after sensory deprivation produced by bilateral whisker trimming from birth to postnatal day 60. By studying the correlated discharge of cortical neuron pairs, we found evidence for strong correlated firing in control animals, and this synchrony was almost absent among pairs of cortical barrel neurons in deprived animals. The degree of synchrony impairment was different in subregions of rat barrel cortex. The model that best fits the data is that cortical neurons receiving direct inputs from the primary sensory (lemniscal) pathway show the greatest decrement in synchrony following sensory deprivation, while neurons with diverse inputs from other areas of thalamus and cortex are relatively less affected in this dimension of cortical function.

  18. Mapping plasticity in the forepaw digit barrel subfield of rat brains using functional MRI

    PubMed Central

    Weng, Jun-Cheng; Chuang, Kai-Hsiang; Goloshevsky, Artem; Dodd, Stephen J.; Sharer, Kathryn

    2012-01-01

    The topographic organization of the forepaw barrel subfield in layer IV of rat primary somatosensory cortex (S1) is a good model for studying neural function and plasticity. The goal of this study was to test the feasibility of functional MRI (fMRI) to map the forepaw digit representations in the S1 of the rat and its plasticity after digit amputation. Three dimentional echo-planar imaging with 300 micron isotropic resolution at 11.7 T was used to achieve high signal-to-noise ratios and laminar layer resolution. By alternating electrical stimulation of the 2nd (D2) and 4th (D4) digits, functional activation in layer IV of the barrel subfields could be distinguished using a differential analysis. Furthermore, two and a half months after the amputation of the 3rd digit in baby rats, the overlapping area between D2 and D4 representations was increased. This indicates that the forepaw barrel subfield previously associated with the ablated digit is now associated with the representation of nearby digits, which is consistent with studies using electrophysiology and cytochrome oxidase staining. PMID:20804851

  19. Plasticity-Related Gene 1 Affects Mouse Barrel Cortex Function via Strengthening of Glutamatergic Thalamocortical Transmission.

    PubMed

    Unichenko, Petr; Kirischuk, Sergei; Yang, Jenq-Wei; Baumgart, Jan; Roskoden, Thomas; Schneider, Patrick; Sommer, Angela; Horta, Guilherme; Radyushkin, Konstantin; Nitsch, Robert; Vogt, Johannes; Luhmann, Heiko J

    2016-07-01

    Plasticity-related gene-1 (PRG-1) is a brain-specific protein that modulates glutamatergic synaptic transmission. Here we investigated the functional role of PRG-1 in adolescent and adult mouse barrel cortex both in vitro and in vivo. Compared with wild-type (WT) animals, PRG-1-deficient (KO) mice showed specific behavioral deficits in tests assessing sensorimotor integration and whisker-based sensory discrimination as shown in the beam balance/walking test and sandpaper tactile discrimination test, respectively. At P25-31, spontaneous network activity in the barrel cortex in vivo was higher in KO mice compared with WT littermates, but not at P16-19. At P16-19, sensory evoked cortical responses in vivo elicited by single whisker stimulation were comparable in KO and WT mice. In contrast, at P25-31 evoked responses were smaller in amplitude and longer in duration in WT animals, whereas KO mice revealed no such developmental changes. In thalamocortical slices from KO mice, spontaneous activity was increased already at P16-19, and glutamatergic thalamocortical inputs to Layer 4 spiny stellate neurons were potentiated. We conclude that genetic ablation of PRG-1 modulates already at P16-19 spontaneous and evoked excitability of the barrel cortex, including enhancement of thalamocortical glutamatergic inputs to Layer 4, which distorts sensory processing in adulthood.

  20. Amyloid β-Protein C-Terminal Fragments: Formation of Cylindrins and β-Barrels.

    PubMed

    Do, Thanh D; LaPointe, Nichole E; Nelson, Rebecca; Krotee, Pascal; Hayden, Eric Y; Ulrich, Brittany; Quan, Sarah; Feinstein, Stuart C; Teplow, David B; Eisenberg, David; Shea, Joan-Emma; Bowers, Michael T

    2016-01-20

    In order to evaluate potential therapeutic targets for treatment of amyloidoses such as Alzheimer's disease (AD), it is essential to determine the structures of toxic amyloid oligomers. However, for the amyloid β-protein peptide (Aβ), thought to be the seminal neuropathogenetic agent in AD, its fast aggregation kinetics and the rapid equilibrium dynamics among oligomers of different size pose significant experimental challenges. Here we use ion-mobility mass spectrometry, in combination with electron microscopy, atomic force microscopy, and computational modeling, to test the hypothesis that Aβ peptides can form oligomeric structures resembling cylindrins and β-barrels. These structures are hypothesized to cause neuronal injury and death through perturbation of plasma membrane integrity. We show that hexamers of C-terminal Aβ fragments, including Aβ(24-34), Aβ(25-35) and Aβ(26-36), have collision cross sections similar to those of cylindrins. We also show that linking two identical fragments head-to-tail using diglycine increases the proportion of cylindrin-sized oligomers. In addition, we find that larger oligomers of these fragments may adopt β-barrel structures and that β-barrels can be formed by folding an out-of-register β-sheet, a common type of structure found in amyloid proteins.

  1. Amyloid β-Protein C-terminal Fragments: Formation of Cylindrins and β-barrels

    PubMed Central

    Do, Thanh D.; LaPointe, Nichole E.; Nelson, Rebecca; Krotee, Pascal; Hayden, Eric Y.; Ulrich, Brittany; Quan, Sarah; Feinstein, Stuart C.; Teplow, David B.; Eisenberg, David; Shea, Joan-Emma; Bowers, Michael T.

    2016-01-01

    In order to evaluate potential therapeutic targets for treatment of amyloidoses such as Alzheimer’s disease (AD), it is essential to determine the structures of toxic amyloid oligomers. However, for the amyloid β-protein peptide (Aβ), thought to be the seminal neuropathogenetic agent in AD, its fast aggregation kinetics and the rapid equilibrium dynamics among oligomers of different size pose significant experimental challenges. Here we use ion-mobility mass spectrometry, in combination with electron microscopy, atomic force microscopy, and computational modeling, to test the hypothesis that Aβ peptides can form oligomeric structures resembling cylindrins and β-barrels. These structures are hypothesized to cause neuronal injury and death through perturbation of plasma membrane integrity. We show that hexamers of C-terminal Aβ fragments, including Aβ(24-34), Aβ(25-35) and Aβ(26-36), have collision cross-sections similar to those of cylindrins. We also show that linking two identical fragments head-to-tail using di-glycine increases the proportion of cylindrin-sized oligomers. In addition, we find that larger oligomers of these fragments may adopt β-barrel structures and that β-barrels can be formed by folding an out-of-register β-sheet, a common type of structure found in amyloid proteins. PMID:26700445

  2. Performance of Prototypes for the Barrel Part of the ANDA Electromagnetic Calorimeter

    NASA Astrophysics Data System (ADS)

    Rosenbaum, Christoph; Diehl, S.; Dormenev, V.; Drexler, P.; Kavatsyuk, M.; Kuske, T.; Nazarenko, S.; Novotny, R.; Rosier, P.; Ryazantsev, A.; Wieczorek, P.; Wilms, A.; Zaunick, H.-G.; P¯ANDA Collaboration

    2016-08-01

    The performance of the most recent prototypes of the ANDA barrel electromagnetic calorimeter (EMC) will be compared. The first large scale prototype PROTO60 was designed to test the performance of the improved tapered lead tungstate crystals (PWO-II). The PROTO60 which consists of 6 × 10 crystals was tested at various accelerator facilities over the complete envisaged energy range fulfilling the requirements of the TDR of the ANDA EMC in terms of energy, position and time resolution. To realize the final barrel geometry and to test the final front end electronics, a second prototype PROTO120 has been constructed. It represents a larger section of a barrel slice, containing the most tapered crystals and the close to final components for the ANDA EMC. The performance of both prototypes will be compared with a focus on the analysis procedure including the signal extraction, noise rejection, calibration and the energy resolution. In addition, the influence of the non-uniformity of the crystal on the energy resolution will be discussed.

  3. A Novel Mitosomal β-Barrel Outer Membrane Protein in Entamoeba

    PubMed Central

    Santos, Herbert J.; Imai, Kenichiro; Makiuchi, Takashi; Tomii, Kentaro; Horton, Paul; Nozawa, Akira; Ibrahim, Mohamed; Tozawa, Yuzuru; Nozaki, Tomoyoshi

    2015-01-01

    Entamoeba possesses a highly divergent mitochondrion-related organelle known as the mitosome. Here, we report the discovery of a novel protein in Entamoeba, which we name Mitosomal β-barrel Outer Membrane Protein of 30 kDa (MBOMP30). Initially identified through in silico analysis, we experimentally confirmed that MBOMP30 is indeed a β-barrel protein. Circular dichroism analysis showed MBOMP30 has a predominant β-sheet structure. Localization to Entamoeba histolytica mitosomes was observed through Percoll-gradient fractionation and immunofluorescence assay. Mitosomal membrane integration was demonstrated by carbonate fractionation, proteinase K digestion, and immunoelectron microscopy. Interestingly, the deletion of the putative β-signal, a sequence believed to guide β-barrel outer membrane protein (BOMP) assembly, did not affect membrane integration, but abolished the formation of a ~240 kDa complex. MBOMP30 represents only the seventh subclass of eukaryotic BOMPs discovered to date and lacks detectable homologs outside Entamoeba, suggesting that it may be unique to Entamoeba mitosomes. PMID:25711150

  4. Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

    PubMed Central

    Iadanza, Matthew G.; Higgins, Anna J.; Schiffrin, Bob; Calabrese, Antonio N.; Brockwell, David J.; Ashcroft, Alison E.; Radford, Sheena E.; Ranson, Neil A.

    2016-01-01

    The β-barrel assembly machinery (BAM) is a ∼203 kDa complex of five proteins (BamA–E), which is essential for viability in E. coli. BAM promotes the folding and insertion of β-barrel proteins into the outer membrane via a poorly understood mechanism. Several current models suggest that BAM functions through a ‘lateral gating' motion of the β-barrel of BamA. Here we present a cryo-EM structure of the BamABCDE complex, at 4.9 Å resolution. The structure is in a laterally open conformation showing that gating is independent of BamB binding. We describe conformational changes throughout the complex and interactions between BamA, B, D and E, and the detergent micelle that suggest communication between BAM and the lipid bilayer. Finally, using an enhanced reconstitution protocol and functional assays, we show that for the outer membrane protein OmpT, efficient folding in vitro requires lateral gating in BAM. PMID:27686148

  5. Improving the resistance of a eukaryotic β-barrel protein to thermal and chemical perturbations.

    PubMed

    Gessmann, Dennis; Mager, Frauke; Naveed, Hammad; Arnold, Thomas; Weirich, Sara; Linke, Dirk; Liang, Jie; Nussberger, Stephan

    2011-10-14

    β-Barrel membrane proteins have regular structures with extensive hydrogen-bond networks between their transmembrane (TM) β-strands, which stabilize their protein fold. Nevertheless, weakly stable TM regions, which are important for the protein function and interaction with other proteins, exist. Here, we report on the apparent stability of human Tom40A, a member of the "mitochondrial porin family" and main constituent of the mitochondrial protein-conducting channel TOM (translocase of the outer membrane). Using a physical interaction model, TmSIP, for β-barrel membrane proteins, we have identified three unfavorable β-strands in the TM domain of the protein. Substitution of key residues inside these strands with hydrophobic amino acids results in a decreased sensitivity of the protein to chemical and/or thermal denaturation. The apparent melting temperature observed when denatured at a rate of 1 °C per minute is shifted from 73 to 84 °C. Moreover, the sensitivity of the protein to denaturant agents is significantly lowered. Further, we find a reduced tendency for the mutated protein to form dimers. We propose that the identified weakly stable β-strands 1, 2 and 9 of human Tom40A play an important role in quaternary protein-protein interactions within the mammalian TOM machinery. Our results show that the use of empirical energy functions to model the apparent stability of β-barrel membrane proteins may be a useful tool in the field of nanopore bioengineering.

  6. Improving the Resistance of a Eukaryotic β-Barrel Protein to Thermal and Chemical Perturbation

    PubMed Central

    Gessmann, Dennis; Mager, Frauke; Naveed, Hammad; Arnold, Thomas; Weirich, Sara; Linke, Dirk; Liang, Jie; Nussberger, Stephan

    2013-01-01

    Beta-barrel membrane proteins have regular structures with extensive hydrogen bonding networks between their transmembrane (TM) β-strands, which stabilize their protein fold. Nevertheless, weakly stable TM regions exist, which are important for the protein function and interaction with other proteins. Here, we report on the apparent stability of human Tom40A, a member of the ‘mitochondrial porin family’ and main constituent of the mitochondrial protein-conducting channel TOM. Using a physical interaction model TmSIP for β-barrel membrane proteins, we have identified three β-strands unfavorable in the TM domain of the protein. Substitution of key residues inside these strands with hydrophobic amino acids results in a decreased sensitivity of the protein to chemical and/or thermal denaturation. The apparent melting temperature observed when denatured at a rate of one degree per minute, is shifted from 73 to 84 °C. Moreover, the sensitivity of the protein to denaturant agents is significantly lowered. Further, we find a reduced tendency for the mutated protein to form dimers. We propose that the identified weakly stable β-strands 1, 2 and 9 of human Tom40A play an important role in quaternary protein-protein interactions within the mammalian TOM machinery. Our results show that the use of empirical energy functions to model the apparent stability of β-barrel membrane proteins may be a useful tool in the field of nanopore bioengineering. PMID:21835183

  7. Shifts in Developmental Timing, and Not Increased Levels of Experience-Dependent Neuronal Activity, Promote Barrel Expansion in the Primary Somatosensory Cortex of Rats Enucleated at Birth

    PubMed Central

    Fetter-Pruneda, Ingrid; Ibarrarán-Viniegra, Ana Sofía; Martínez-Martínez, Eduardo; Sandoval-Velasco, Marcela; Uribe-Figueroa, Laura; Padilla-Cortés, Patricia; Mercado-Célis, Gabriela; Gutiérrez-Ospina, Gabriel

    2013-01-01

    Birth-enucleated rodents display enlarged representations of whiskers (i.e., barrels of the posteromedial subfield) in the primary somatosensory cortex. Although the historical view maintains that barrel expansion is due to incremental increases in neuronal activity along the trigeminal pathway during postnatal development, recent evidence obtained in experimental models of intramodal plasticity challenges this view. Here, we re-evaluate the role of experience-dependent neuronal activity on barrel expansion in birth-enucleated rats by combining various anatomical methods and sensory deprivation paradigms. We show that barrels in birth-enucleated rats were already enlarged by the end of the first week of life and had levels of metabolic activity comparable to those in control rats at different ages. Dewhiskering after the postnatal period of barrel formation did not prevent barrel expansion in adult, birth-enucleated rats. Further, dark rearing and enucleation after barrel formation did not lead to expanded barrels in adult brains. Because incremental increases of somatosensory experience did not promote barrel expansion in birth-enucleated rats, we explored whether shifts of the developmental timing could better explain barrel expansion during the first week of life. Accordingly, birth-enucleated rats show earlier formation of barrels, accelerated growth of somatosensory thalamocortical afferents, and an earlier H4 deacetylation. Interestingly, when H4 deacetylation was prevented with a histone deacetylases inhibitor (valproic acid), barrel specification timing returned to normal and barrel expansion did not occur. Thus, we provide evidence supporting that shifts in developmental timing modulated through epigenetic mechanisms, and not increased levels of experience dependent neuronal activity, promote barrel expansion in the primary somatosensory cortex of rats enucleated at birth. PMID:23372796

  8. Automated mass spectrometer grows up

    SciTech Connect

    McInteer, B.B.; Montoya, J.G.; Stark, E.E.

    1984-01-01

    In 1980 we reported the development of an automated mass spectrometer for large scale batches of samples enriched in nitrogen-15 as ammonium salts. Since that time significant technical progress has been made in the instrument. Perhaps more significantly, administrative and institutional changes have permitted the entire effort to be transferred to the private sector from its original base at the Los Alamos National Laboratory. This has ensured the continuance of a needed service to the international scientific community as revealed by a development project at a national laboratory, and is an excellent example of beneficial technology transfer to private industry.

  9. Modular multichannel surface plasmon spectrometer

    NASA Astrophysics Data System (ADS)

    Neuert, G.; Kufer, S.; Benoit, M.; Gaub, H. E.

    2005-05-01

    We have developed a modular multichannel surface plasmon resonance (SPR) spectrometer on the basis of a commercially available hybrid sensor chip. Due to its modularity this inexpensive and easy to use setup can readily be adapted to different experimental environments. High temperature stability is achieved through efficient thermal coupling of individual SPR units. With standard systems the performance of the multichannel instrument was evaluated. The absorption kinetics of a cysteamine monolayer, as well as the concentration dependence of the specific receptor-ligand interaction between biotin and streptavidin was measured.

  10. Triple axis and spins spectrometers

    SciTech Connect

    Trevino, S.F.

    1993-01-01

    In the paper are described the triple axis and spin polarized inelastic neutron scattering (SPINS) spectrometers which are installed at the NIST Cold Neutron Research Facility (CNRF). The general principle of operation of these two instruments is described in sufficient detail to allow the reader to make an informed decision as to their usefulness for his needs. However, it is the intention of the staff at the CNRF to provide the expert resources for their efficient use in any given situation. Thus, the work is not intended as a user manual but rather as a guide into the range of applicability of the two instruments.

  11. Alpha-particle spectrometer experiment

    NASA Technical Reports Server (NTRS)

    Gorenstein, P.; Bjorkholm, P.

    1972-01-01

    Mapping the radon emanation of the moon was studied to find potential areas of high activity by detection of radon isotopes and their daughter products. It was felt that based on observation of regions overflown by Apollo spacecraft and within the field of view of the alpha-particle spectrometer, a radon map could be constructed, identifying and locating lunar areas of outgassing. The basic theory of radon migration from natural concentrations of uranium and thorium is discussed in terms of radon decay and the production of alpha particles. The preliminary analysis of the results indicates no significant alpha emission.

  12. Wide-range CCD spectrometer

    NASA Astrophysics Data System (ADS)

    Sokolova, Elena A.; Reyes Cortes, Santiago D.

    1996-08-01

    The utilization of wide range spectrometers is a very important feature for the design of optical diagnostics. This paper describes an innovative approach, based on charged coupled device, which allows to analyze different spectral intervals with the same diffraction grating. The spectral interval is varied by changing the position of the entrance slit when the grating is stationary. The optical system can also include a spherical mirror. In this case the geometric position of the mirror is calculated aiming at compensating the first order astigmatism and the meridional coma of the grating. This device is planned to be used in Thomson scattering diagnostic of the TOKAMAK of Instituto Superior Tecnico, Lisbon (ISTTOK).

  13. Portable neutron spectrometer and dosimeter

    DOEpatents

    Waechter, David A.; Erkkila, Bruce H.; Vasilik, Dennis G.

    1985-01-01

    The disclosure relates to a battery operated neutron spectrometer/dosimeter utilizing a microprocessor, a built-in tissue equivalent LET neutron detector, and a 128-channel pulse height analyzer with integral liquid crystal display. The apparatus calculates doses and dose rates from neutrons incident on the detector and displays a spectrum of rad or rem as a function of keV per micron of equivalent tissue and also calculates and displays accumulated dose in millirads and millirem as well as neutron dose rates in millirads per hour and millirem per hour.

  14. Portable neutron spectrometer and dosimeter

    DOEpatents

    Waechter, D.A.; Erkkila, B.H.; Vasilik, D.G.

    The disclosure relates to a battery operated neutron spectrometer/dosimeter utilizing a microprocessor, a built-in tissue equivalent LET neutron detector, and a 128-channel pulse height analyzer with integral liquid crystal display. The apparatus calculates doses and dose rates from neutrons incident on the detector and displays a spectrum of rad or rem as a function of keV per micron of equivalent tissue and also calculates and displays accumulated dose in millirads and millirem as well as neutron dose rates in millirads per hour and millirem per hour.

  15. Alpha-particle spectrometer experiment

    NASA Technical Reports Server (NTRS)

    Gorenstein, P.; Bjorkholm, P.

    1972-01-01

    Mapping the radon emanation of the moon was studied to find potential areas of high activity by detection of radon isotopes and their daughter products. It was felt that based on observation of regions overflown by Apollo spacecraft and within the field of view of the alpha-particle spectrometer, a radon map could be constructed, identifying and locating lunar areas of outgassing. The basic theory of radon migration from natural concentrations of uranium and thorium is discussed in terms of radon decay and the production of alpha particles. The preliminary analysis of the results indicates no significant alpha emission.

  16. FPGA based pulsed NQR spectrometer

    NASA Astrophysics Data System (ADS)

    Hemnani, Preeti; Rajarajan, A. K.; Joshi, Gopal; Motiwala, Paresh D.; Ravindranath, S. V. G.

    2014-04-01

    An NQR spectrometer for the frequency range of 1 MHz to 5 MHZ has been designed constructed and tested using an FPGA module. Consisting of four modules viz. Transmitter, Probe, Receiver and computer controlled (FPGA & Software) module containing frequency synthesizer, pulse programmer, mixer, detection and display, the instrument is capable of exciting nuclei with a power of 200W and can detect signal of a few microvolts in strength. 14N signal from NaNO2 has been observed with the expected signal strength.

  17. Experiment M408: Beta spectrometer

    NASA Technical Reports Server (NTRS)

    Marbach, J. R.

    1971-01-01

    The beta spectrometer functioned as planned throughout the Gemini 10 mission. The cool temperatures that were recorded from the instrument during the mission were indicative that the evaporative cooler, coupled with apparently lower-than-expected spacecraft-adapter temperatures, maintained ideal operating conditions. The data facilitate a good analysis of the electron directional distribution. The omnidirectional flux that was calculated is apparently consistent with previous measurements. Representative electron spectra, measured during the Gemini 12 mission, established the apparent decay of the artificially injected electrons (from the Starfish high altitude nuclear test) to such low levels that natural trapped electrons were becoming detectable.

  18. EMISSIONS OF POLYCHLORINATED DIBENZO-P-DIOXINS AND POLYCHLORINATED DIBENZOFURANS FROM THE OPEN BURNING OF HOUSEHOLD WASTE IN BARRELS

    EPA Science Inventory

    Backyard burning of household waste in barrels is a common waste disposal practice for which pollutant emissions have not been well characterized. This study measured the emissions of several pollutants, including polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofura...

  19. EMISSIONS OF POLYCHLORINATED DIBENZO-P-DIOXINS AND POLYCHLORINATED DIBENZOFURANS FROM THE OPEN BURNING OF HOUSEHOLD WASTE IN BARRELS

    EPA Science Inventory

    Backyard burning of household waste in barrels is a common waste disposal practice for which pollutant emissions have not been well characterized. This study measured the emissions of several pollutants, including polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofura...

  20. TonB-dependent transporter FhuA in planar lipid bilayers: partial exit of its plug from the barrel.

    PubMed

    Udho, Eshwar; Jakes, Karen S; Finkelstein, Alan

    2012-08-28

    TonB-dependent transporters (TBDTs), which transport iron-chelating siderophores and vitamin B(12) across the outer membrane of Gram-negative bacteria, share a conserved architecture of a 22-stranded β-barrel with an amino-terminal plug domain occluding the barrel. We previously reported that we could induce TBDTs to reversibly open in planar lipid bilayers via the use of urea and that these channels were responsive to physiological concentrations of ligands. Here we report that in the presence of urea, trypsin can cleave the amino-terminal 67 residues of the plug of the TonB-dependent transporter FhuA, as assessed by gel shift and mass spectrometry assays. On the bilayer, trypsin treatment in the presence of urea resulted in the induced conductance no longer being reversed upon removal of urea, suggesting that urea opens intact FhuA channels by pulling the plug at least partly out of the barrel and that removal of the urea then allows reinsertion of the plug into the barrel. When expressed separately, the FhuA plug domain was found to be a mostly unfolded structure that was able to occlude isolated FhuA β-barrels inserted into the membrane. Thus, although folded in the barrel, the plug need not be folded upon exiting the barrel. The rate of insertion of the β-barrels into the membrane was tremendously increased in the presence of an osmotic gradient provided by either urea or glycerol. Negative staining electron microscopy showed that FhuA in a detergent solution formed vesicles, thus explaining why an osmotic gradient promoted the insertion of FhuA into membranes.