Sample records for sphere reference system

  1. Design and tolerance analysis of a transmission sphere by interferometer model

    NASA Astrophysics Data System (ADS)

    Peng, Wei-Jei; Ho, Cheng-Fong; Lin, Wen-Lung; Yu, Zong-Ru; Huang, Chien-Yao; Hsu, Wei-Yao

    2015-09-01

    The design of a 6-in, f/2.2 transmission sphere for Fizeau interferometry is presented in this paper. To predict the actual performance during design phase, we build an interferometer model combined with tolerance analysis in Zemax. Evaluating focus imaging is not enough for a double pass optical system. Thus, we study the interferometer model that includes system error, wavefronts reflected from reference surface and tested surface. Firstly, we generate a deformation map of the tested surface. Because of multiple configurations in Zemax, we can get the test wavefront and the reference wavefront reflected from the tested surface and the reference surface of transmission sphere respectively. According to the theory of interferometry, we subtract both wavefronts to acquire the phase of tested surface. Zernike polynomial is applied to transfer the map from phase to sag and to remove piston, tilt and power. The restored map is the same as original map; because of no system error exists. Secondly, perturbed tolerances including fabrication of lenses and assembly are considered. The system error occurs because the test and reference beam are no longer common path perfectly. The restored map is inaccurate while the system error is added. Although the system error can be subtracted by calibration, it should be still controlled within a small range to avoid calibration error. Generally the reference wavefront error including the system error and the irregularity of the reference surface of 6-in transmission sphere is measured within peak-to-valley (PV) 0.1 λ (λ=0.6328 um), which is not easy to approach. Consequently, it is necessary to predict the value of system error before manufacture. Finally, a prototype is developed and tested by a reference surface with PV 0.1 λ irregularity.

  2. Application of reference-modified density functional theory: Temperature and pressure dependences of solvation free energy.

    PubMed

    Sumi, Tomonari; Maruyama, Yutaka; Mitsutake, Ayori; Mochizuki, Kenji; Koga, Kenichiro

    2018-02-05

    Recently, we proposed a reference-modified density functional theory (RMDFT) to calculate solvation free energy (SFE), in which a hard-sphere fluid was introduced as the reference system instead of an ideal molecular gas. Through the RMDFT, using an optimal diameter for the hard-sphere reference system, the values of the SFE calculated at room temperature and normal pressure were in good agreement with those for more than 500 small organic molecules in water as determined by experiments. In this study, we present an application of the RMDFT for calculating the temperature and pressure dependences of the SFE for solute molecules in water. We demonstrate that the RMDFT has high predictive ability for the temperature and pressure dependences of the SFE for small solute molecules in water when the optimal reference hard-sphere diameter determined for each thermodynamic condition is used. We also apply the RMDFT to investigate the temperature and pressure dependences of the thermodynamic stability of an artificial small protein, chignolin, and discuss the mechanism of high-temperature and high-pressure unfolding of the protein. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  3. Density Measurement System for Weights of 1 kg to 20 kg Using Hydrostatic Weighing

    NASA Astrophysics Data System (ADS)

    Lee, Yong Jae; Lee, Woo Gab; Abdurahman, Mohammed; Kim, Kwang Pyo

    This paper presents a density measurement system to determine density of weights from 1 kg to 20 kg using hydrostatic weighing. The system works based on Archimedes principle. The density of reference liquid is determined using this setup while determining the density of the test weight. Density sphere is used as standard density ball to determine density of the reference liquid. A new immersion pan is designed for dual purpose to carry the density sphere and the cylindrical test weight for weighing in liquid. Main parts of the setup are an electronic balance, a thermostat controlled liquid bath, reference weights designed for bottom weighing, dual purpose immersion pans and stepping motors to load and unload in weighing process. The results of density measurement will be evaluated as uncertainties for weights of 1 kg to 20 kg.

  4. Reference hypernetted chain theory for ferrofluid bilayer: Distribution functions compared with Monte Carlo

    NASA Astrophysics Data System (ADS)

    Polyakov, Evgeny A.; Vorontsov-Velyaminov, Pavel N.

    2014-08-01

    Properties of ferrofluid bilayer (modeled as a system of two planar layers separated by a distance h and each layer carrying a soft sphere dipolar liquid) are calculated in the framework of inhomogeneous Ornstein-Zernike equations with reference hypernetted chain closure (RHNC). The bridge functions are taken from a soft sphere (1/r12) reference system in the pressure-consistent closure approximation. In order to make the RHNC problem tractable, the angular dependence of the correlation functions is expanded into special orthogonal polynomials according to Lado. The resulting equations are solved using the Newton-GRMES algorithm as implemented in the public-domain solver NITSOL. Orientational densities and pair distribution functions of dipoles are compared with Monte Carlo simulation results. A numerical algorithm for the Fourier-Hankel transform of any positive integer order on a uniform grid is presented.

  5. Orsphere: Physics Measurments For Bare, HEU(93.2)-Metal Sphere

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marshall, Margaret A.; Bess, John D.; Briggs, J. Blair

    In the early 1970s Dr. John T. Mihalczo (team leader), J.J. Lynn, and J.R. Taylor performed experiments at the Oak Ridge Critical Experiments Facility (ORCEF) with highly enriched uranium (HEU) metal (called Oak Ridge Alloy or ORALLOY) in an attempt to recreate GODIVA I results with greater accuracy than those performed at Los Alamos National Laboratory in the 1950s (HEU-MET-FAST-001). The purpose of the Oak Ridge ORALLOY Sphere (ORSphere) experiments was to estimate the unreflected and unmoderated critical mass of an idealized sphere of uranium metal corrected to a density, purity, and enrichment such that it could be compared withmore » the GODIVA I experiments. “The very accurate description of this sphere, as assembled, establishes it as an ideal benchmark for calculational methods and cross-section data files” (Reference 1). While performing the ORSphere experiments care was taken to accurately document component dimensions (±0.0001 inches), masses (±0.01 g), and material data. The experiment was also set up to minimize the amount of structural material in the sphere proximity. Two, correlated spheres were evaluated and judged to be acceptable as criticality benchmark experiments. This evaluation is given in HEU-MET-FAST-100. The second, smaller sphere was used for additional reactor physics measurements. Worth measurements (Reference 1, 2, 3 and 4), the delayed neutron fraction (Reference 3, 4 and 5) and surface material worth coefficient (Reference 1 and 2) are all measured and judged to be acceptable as benchmark data. The prompt neutron decay (Reference 6), relative fission density (Reference 7) and relative neutron importance (Reference 7) were measured, but are not evaluated. Information for the evaluation was compiled from References 1 through 7, the experimental logbooks 8 and 9 ; additional drawings and notes provided by the experimenter; and communication with the lead experimenter, John T. Mihalczo.« less

  6. The implementation of aerial object recognition algorithm based on contour descriptor in FPGA-based on-board vision system

    NASA Astrophysics Data System (ADS)

    Babayan, Pavel; Smirnov, Sergey; Strotov, Valery

    2017-10-01

    This paper describes the aerial object recognition algorithm for on-board and stationary vision system. Suggested algorithm is intended to recognize the objects of a specific kind using the set of the reference objects defined by 3D models. The proposed algorithm based on the outer contour descriptor building. The algorithm consists of two stages: learning and recognition. Learning stage is devoted to the exploring of reference objects. Using 3D models we can build the database containing training images by rendering the 3D model from viewpoints evenly distributed on a sphere. Sphere points distribution is made by the geosphere principle. Gathered training image set is used for calculating descriptors, which will be used in the recognition stage of the algorithm. The recognition stage is focusing on estimating the similarity of the captured object and the reference objects by matching an observed image descriptor and the reference object descriptors. The experimental research was performed using a set of the models of the aircraft of the different types (airplanes, helicopters, UAVs). The proposed orientation estimation algorithm showed good accuracy in all case studies. The real-time performance of the algorithm in FPGA-based vision system was demonstrated.

  7. Directional spectral emissivity measurement system

    NASA Technical Reports Server (NTRS)

    Halyo, Nesim (Inventor); Pandey, Dhirendra K. (Inventor)

    1992-01-01

    Apparatus and process for determining the emissivity of a test specimen including an integrated sphere having two concentric walls with a coolant circulating therebetween, and disposed within a chamber which may be under ambient, vacuum or inert gas conditions. A reference sample is disposed within the sphere with a monochromatic light source in optical alignment therewith. A pyrometer is in optical alignment with the test sample for obtaining continuous test sample temperature measurements during a test. An arcuate slit port is provided through the spaced concentric walls of the integrating sphere with a movable monochromatic light source extending through and movable along the arcuate slit port. A detector system extends through the integrating sphere for continuously detecting an integrated signal indicative of all radiation within its field of view, as a function of the emissivity of the test specimen at various temperatures and various angle position of the monochromatic light source. A furnace for heating the test sample to approximately 3000 K. and control mechanism for transferring the heated sample from the furnace to the test sample port in the integrating sphere is also contained within the chamber.

  8. Electrical resistivity of liquid lanthanides using charge hard sphere system

    NASA Astrophysics Data System (ADS)

    Sonvane, Y. A.; Thakor, P. B.; Jani, A. R.

    2013-06-01

    In the present paper, we have studied electrical resistivity (ρ) of liquid lanthanides. To describe the structural information, the structure factor S(q) due to the charged hard sphere (CHS) reference systems is used along with our newly constructed model potential. To see the influence of exchange and correlation effect on the electrical resistivity (ρ) have used different local field correction functions like Hartree (H), Sarkar et al (S) and Taylor (T). Lastly we conclude that the proper choice of the model potential along with local field correction function plays a vital role to the study of the electrical resistivity (ρ).

  9. Relative range error evaluation of terrestrial laser scanners using a plate, a sphere, and a novel dual-sphere-plate target.

    PubMed

    Muralikrishnan, Bala; Rachakonda, Prem; Lee, Vincent; Shilling, Meghan; Sawyer, Daniel; Cheok, Geraldine; Cournoyer, Luc

    2017-12-01

    Terrestrial laser scanners (TLS) are a class of 3D imaging systems that produce a 3D point cloud by measuring the range and two angles to a point. The fundamental measurement of a TLS is range. Relative range error is one component of the overall range error of TLS and its estimation is therefore an important aspect in establishing metrological traceability of measurements performed using these systems. Target geometry is an important aspect to consider when realizing the relative range tests. The recently published ASTM E2938-15 mandates the use of a plate target for the relative range tests. While a plate target may reasonably be expected to produce distortion free data even at far distances, the target itself needs careful alignment at each of the relative range test positions. In this paper, we discuss relative range experiments performed using a plate target and then address the advantages and limitations of using a sphere target. We then present a novel dual-sphere-plate target that draws from the advantages of the sphere and the plate without the associated limitations. The spheres in the dual-sphere-plate target are used simply as fiducials to identify a point on the surface of the plate that is common to both the scanner and the reference instrument, thus overcoming the need to carefully align the target.

  10. Bulk properties of two-phase disordered media. I. Cluster expansion for the effective dielectric constant of dispersions of penetrable spheres

    NASA Astrophysics Data System (ADS)

    Torquato, S.

    1984-12-01

    We derive a cluster expansion for the effective dielectric constant ɛ* of a dispersion of equal-sized spheres distributed with arbitrary degree of impenetrability. The degree of impenetrability is characterized by some parameter λ whose value varies between zero (in the case of randomly centered spheres, i.e., fully penetrable spheres) and unity (in the instance of totally impenetrable spheres). This generalizes the results of Felderhof, Ford, and Cohen who obtain a cluster expansion for ɛ* for the specific case of a dispersion of totally impenetrable spheres, i.e., the instance λ=1. We describe the physical significance of the contributions to the average polarization of the two-phase system which arise from inclusion-overlap effects. Using these results, we obtain a density expansion for ɛ*, which is exact through second order in the number density ρ, and give the physical interpretations of all of the cluster integrals that arise here. The use of a certain family of equilibrium sphere distributions is suggested in order to systematically study the effects of details of the microstructure on ɛ* through second order in ρ. We show, furthermore, that the second-order term can be written as a sum of the contribution from a reference system of totally impenetrable spheres and an excess contribution, which only involves effects due to overlap of pairs of inclusions. We also obtain an expansion for ɛ* which is exact through second order in φ2, where φ2 is the sphere volume fraction. We evaluate, for concreteness, some of the integrals that arise in this study, for arbitrary λ, in the permeable-sphere model and in the penetrable concentric-shell model introduced in this study.

  11. Spherical Lu2O2S:Eu3+ micro/nano-structure: Controlled synthesis and luminescence properties

    NASA Astrophysics Data System (ADS)

    Zhang, Bowen; Zou, Haifeng; Dai, Yunzhi; Guan, Hongxia; Song, Yanhua; Zheng, Keyan; Zhou, Xiuqing; Shi, Zhan; Sheng, Ye

    2017-02-01

    Monodisperse and uniform Lu2O2S:Eu3+ luminescent spheres have been successfully synthesized through a facile hydrothermal method followed by a subsequent calcination process. The sizes of the spheres can be tuned in the range of 65 nm-295 nm by only changing the pH value of the system. It is indicated that the luminescence properties of the spherical phosphors were strongly influenced by size of the spheres. Such a size-sensitive luminescence property was interpreted from the structures of the spheres, including the degree of crystallinity, band gap energy, crystal field symmetry around Eu3+. We expected that this study not only can provide important information for size-controlled synthesis of spherical phosphors, but also can give a reference for exploration of size-dependent luminescence.

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marshall, Margaret A.

    In the early 1970s Dr. John T. Mihalczo (team leader), J.J. Lynn, and J.R. Taylor performed experiments at the Oak Ridge Critical Experiments Facility (ORCEF) with highly enriched uranium (HEU) metal (called Oak Ridge Alloy or ORALLOY) in an attempt to recreate GODIVA I results with greater accuracy than those performed at Los Alamos National Laboratory in the 1950s (HEU-MET-FAST-001). The purpose of the Oak Ridge ORALLOY Sphere (ORSphere) experiments was to estimate the unreflected and unmoderated critical mass of an idealized sphere of uranium metal corrected to a density, purity, and enrichment such that it could be compared withmore » the GODIVA I experiments. “The very accurate description of this sphere, as assembled, establishes it as an ideal benchmark for calculational methods and cross-section data files” (Reference 1). While performing the ORSphere experiments care was taken to accurately document component dimensions (±0.0001 inches), masses (±0.01 g), and material data. The experiment was also set up to minimize the amount of structural material in the sphere proximity. Two, correlated spheres were evaluated and judged to be acceptable as criticality benchmark experiments. This evaluation is given in HEU-MET-FAST-100. The second, smaller sphere was used for additional reactor physics measurements. Worth measurements (Reference 1, 2, 3 and 4), the delayed neutron fraction (Reference 3, 4 and 5) and surface material worth coefficient (Reference 1 and 2) are all measured and judged to be acceptable as benchmark data. The prompt neutron decay (Reference 6), relative fission density (Reference 7) and relative neutron importance (Reference 7) were measured, but are not evaluated. Information for the evaluation was compiled from References 1 through 7, the experimental logbooks 8 and 9 ; additional drawings and notes provided by the experimenter; and communication with the lead experimenter, John T. Mihalczo.« less

  13. Multipurpose Fiber Injected-micro-spherical LIDAR System

    NASA Technical Reports Server (NTRS)

    Abdelayem, Hossin; Jamison, Tracee

    2005-01-01

    A technological revolution is occurring in the field of fiber lasers. Over the past two years, the level of power has increased from approx. 100 watts to nearly 1 kilowatt. We are developing a novel fiber laser system, which is a satellite-based LIDAR transmitter of multi-lines. The system is made of a hollow fiber filled with micro-spheres doped with lasing materials. Each sphere has its inherent optical cavity, which makes the system a cavity free and in the same time, emits multi-laser lines for simultaneous multi-task operations. The system is also rugged, compact, lightweight, and durable. Our earlier studies on micro-spheres doped with different laser dyes demonstrated the emission of extremely fine laser lines of less than 3 A line-width, which are of interest for spectroscopic applications, sensing, imaging, and optical communications. Individual dye-doped micro-spheres demonstrated a lasing resonance peaks phenomenon in their fluorescence spectra of linear and nonlinear features that do not exist in the bulk dye solutions. Each individual micro-sphere acts as a laser system with inherent cavity, where the fluorescence line suffers multiple internal reflections within the micro-sphere and gains enough energy to become a laser line. Such resonance peaks are dependent on the sphere's morphology, size, shape, and its refractive index. These resonance peaks are named structural resonance, whispering modes or whispering gallery modes, creeping waves, circumferential waves, surfaces modes, and virtual modes. All of these names refer to the same phenomenon of morphology dependent resonance (MDR), which has already been described and predicted precisely by electromagnetic theory and Lorentz-Mie theory since 1908. The resonance peaks become more obvious when the particle size approaches and exceeds the wavelength of the laser used and the relative index of the particle is greater than that of the surrounding medium. Additional information is included in the original extended abstract.

  14. Estimated critical conditions for UO[sub 2]F[sub 2]--H[sub 2]O systems in fully water-reflected spherical geometry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jordan, W.C.; Turner, J.C.

    1992-12-01

    The purpose of this report is to document reference calculations performed using the SCALE-4.0 code system to determine the critical parameters of UO[sub 2]F[sub 2]-H[sub 2]O spheres. The calculations are an extension of those documented in ORNL/CSD/TM-284. Specifically, the data for low-enriched UO[sub 2]F[sub 2]-H[sub 2]O spheres have been extended to highly enriched uranium. These calculations, together with those reported in ORNL/CSD/TM-284, provide a consistent set of critical parameters (k[sub [infinity

  15. Propagation of a shock wave in a radiating spherically symmetric distribution of matter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Herrera, L.; Nunez, L.

    1987-08-01

    A method used to study the evolution of radiating spheres reported by Herrera et al. (1980) is extended to the case in which the sphere is divided in two regions by a shock wave front. The equations of state at both sides of the shock are different, and the solutions are matched on it via the Rankine-Hugoniot conditions. The outer-region metric is matched with a Vaidya solution on the boundary surface of the sphere. As an example of the procedure, two known solutions for radiating systems are considered. The matter distribution is free of singularities everywhere within the sphere andmore » a Gaussian-like pulse is assumed to carry out a fraction of the total mass. Exploding models are then obtained. Finally, the results are discussed in the light of recent work on gravitational collapse and supernovae. 29 references.« less

  16. Reference to Self and Other in the Digital Public Sphere: The Case of Political Blogs

    ERIC Educational Resources Information Center

    De Cock, Barbara; González Arias, Cristian

    2018-01-01

    In this paper, we analyze how a political blog author (Spanish Alejo Vidal-Quadras) establishes the reference to self and other in his blog entries. We furthermore look into how the commentators to this blog react and establish reference to self and other in the digital public sphere. More concretely, we show that they not only take up the…

  17. Analytic study of a rolling sphere on a rough surface

    NASA Astrophysics Data System (ADS)

    Florea, Olivia A.; Rosca, Ileana C.

    2016-11-01

    In this paper it is realized an analytic study of the rolling's sphere on a rough horizontal plane under the action of its own gravity. The necessities of integration of the system of dynamical equations of motion lead us to find a reference system where the motion equations should be transformed into simpler expressions and which, in the presence of some significant hypothesis to permit the application of some original methods of analytical integration. In technical applications, the bodies may have a free rolling motion or a motion constrained by geometrical relations in assemblies of parts and machine parts. This study involves a lot of investigations in the field of tribology and of applied dynamics accompanied by experiments. Multiple recordings of several trajectories of the sphere, as well as their treatment of images, also followed by statistical processing experimental data allowed highlighting a very good agreement between the theoretical findings and experimental results.

  18. Satellite Ephemeris Correction via Remote Site Observation for Star Tracker Navigation Performance Improvement

    DTIC Science & Technology

    2016-03-01

    squared RMS root mean squared GCRF Geocentric Celestial Reference Frame xi List of Figures Figure Page 1 Geometry of single observation...RA and DEC in the celestial sphere. The Geocentric Celestial Reference Frame (GCRF) is the standard geocentric frame that measures the RA east in the...Figure 2. Right ascension (α) and declination (δ) in the celestial sphere[6] 7 made between geocentric and topocentric angles. Geocentric is referred to

  19. Structural properties of liquid lanthanides using charge hard sphere reference system

    NASA Astrophysics Data System (ADS)

    Thakora, P. B.; Sonvane, Y. A.; Patel, H. P.; Gajjar, P. N.; Jani, A. R.

    2012-06-01

    In the present paper Charge Hard Sphere (CHS) system is employed to investigate the structural properties like long wavelength limit S(0), isothermal compressibility (χT) and coordination number n for some liquid lanthanides viz.: La, Ce, Pr, Nd, Eu, Gd, Tb, Dy, Ho, Er, Yb and Lu. Our well established parameter free model potential is used to describe the electron-ion interaction alongwith sarkar et al. dielectric function. From the present results, it is seen that good agreement between present results and available experimental data have been achieved. At last, we establish the applicability of our parameter free model potential and CHS method to account such structural properties.

  20. Electronic transport properties of 4f shell elements of liquid metal using hard sphere Yukawa system

    NASA Astrophysics Data System (ADS)

    Patel, H. P.; Sonvane, Y. A.; Thakor, P. B.

    2018-04-01

    The electronic transport properties are analyzed for 4f shell elements of liquid metals. To examine the electronic transport properties like electrical resistivity (ρ), thermal conductivity (σ) and thermo electrical power (Q), we used our own parameter free model potential with the Hard Sphere Yukawa (HSY) reference system. The screening effect on aforesaid properties has been examined by using different screening functions like Hartree (H), Taylor (T) and Sarkar (S). The correlations of our resultsand other data with available experimental values are intensely promising. Also, we conclude that our newly constructed parameter free model potential is capable of explaining the above mentioned electronic transport properties.

  1. Fiber optic inclination detector system having a weighted sphere with reference points

    DOEpatents

    Cwalinski, Jeffrey P.

    1995-01-01

    A fiber optic inclination detector system for determining the angular displacement of an object from a reference surface includes a simple mechanical transducer which requires a minimum number of parts and no electrical components. The system employs a single light beam which is split into two light beams and provided to the transducer. Each light beam is amplitude modulated upon reflecting off the transducer to detect inclination. The power values associated with each of the reflected light beams are converted by a pair of photodetectors into voltage signals, and a microprocessor manipulates the voltage signals to provide a measure of the angular displacement between the object and the reference surface.

  2. Dispersivity of Bidisperse Packings of Spheres and Evidence for Distinct Random Structures

    NASA Astrophysics Data System (ADS)

    Scheven, U. M.

    2018-05-01

    The intrinsic longitudinal and transverse dispersivity of bidisperse random packings of spheres with size ratio 5 ∶1 was determined by pulsed field gradient nuclear magnetic resonance, in the dilute regime where small spheres occupy between 0% and 5% of the packings' volume. Small spheres plugging pores systematically raise the mechanical transverse and longitudinal dispersivity above that of reference packings of monodisperse spheres. NMR-derived porosities, widths of velocity distributions, and dispersivities reveal distinct states of structural disorder above and below a relative sphere concentration n /N =1 , where n and N are the number densities of small and large spheres.

  3. Reflective all-sky thermal infrared cloud imager.

    PubMed

    Redman, Brian J; Shaw, Joseph A; Nugent, Paul W; Clark, R Trevor; Piazzolla, Sabino

    2018-04-30

    A reflective all-sky imaging system has been built using a long-wave infrared microbolometer camera and a reflective metal sphere. This compact system was developed for measuring spatial and temporal patterns of clouds and their optical depth in support of applications including Earth-space optical communications. The camera is mounted to the side of the reflective sphere to leave the zenith sky unobstructed. The resulting geometric distortion is removed through an angular map derived from a combination of checkerboard-target imaging, geometric ray tracing, and sun-location-based alignment. A tape of high-emissivity material on the side of the reflector acts as a reference that is used to estimate and remove thermal emission from the metal sphere. Once a bias that is under continuing study was removed, sky radiance measurements from the all-sky imager in the 8-14 μm wavelength range agreed to within 0.91 W/(m 2 sr) of measurements from a previously calibrated, lens-based infrared cloud imager over its 110° field of view.

  4. Free Energy Calculations of Crystalline Hard Sphere Complexes Using Density Functional Theory

    DOE PAGES

    Gunawardana, K. G.S.H.; Song, Xueyu

    2014-12-22

    Recently developed fundamental measure density functional theory (FMT) is used to study binary hard sphere (HS) complexes in crystalline phases. By comparing the excess free energy, pressure and phase diagram, we show that the fundamental measure functional yields good agreements to the available simulation results of AB, AB 2 and AB 13 crystals. Additionally, we use this functional to study the HS models of five binary crystals, Cu 5Zr(C15 b), Cu 51Zr 14(β), Cu 10Zr 7(φ), CuZr(B2) and CuZr 2 (C11 b), which are observed in the Cu-Zr system. The FMT functional gives well behaved minimum for most of themore » hard sphere crystal complexes in the two dimensional Gaussian space, namely a crystalline phase. However, the current version of FMT functional (white Bear) fails to give a stable minimum for the structure Cu 10Zr 7(φ). We argue that the observed solid phases for the HS models of the Cu-Zr system are true thermodynamic stable phases and can be used as a reference system in perturbation calculations.« less

  5. Structure and thermodynamics of asymmetric molecules: Application to linear triatomic dipolar molecules

    NASA Astrophysics Data System (ADS)

    Nichols, Albert L., III; Calef, Daniel F.

    A new method to solve the reference HNC equations is developed to treat systems with both asymmetric short-range and long-range interactions. This method is motivated by the work of Patey and co-workers and uses Lado's free-energy minimizing optimization criteria for the reference HNC approximation. The properties of several fluids composed of linear triatomic molecules with various dipole moments or hard-sphere molecules with different-length dipoles are investigated.

  6. A reference standard for bidirectional reflection distribution function and bidirectional transmission distribution function measurement

    NASA Technical Reports Server (NTRS)

    Witherow, William K. (Inventor)

    1988-01-01

    A Lambertian reference standard for uniformly scattering a beam of light is constructed of a plate having a planar surface with a layer of glue disposed on the surface. An evenly packed layer of monodisperse spheres is set in the layer, and when the standard is used for bi-directional (BRDF) measurements, the spheres are coated with a layer of highly relective substance, such as gold or silver. When the standard is used for bi-directional transmittance distribution function (BTDF) measurements, the spheres are of a transparent material and are provided with a roughened surface, as by acid etching. In this case, the layer of glue is an optical cement, and the plate is of glass, with the spheres, the layer, and the plate all possessing a similar refractive index.

  7. Magnetostatic Surface Field Measurement Facility.

    DTIC Science & Technology

    1986-12-01

    Sphere 106 4 Page C .2 Acoustically Hard Prolate 10 8 HC.3 Perfectly Conducting Sphere 110 C .4 Some Implications 113 C .5 References 115 APPENDIX D 117 0.1...I/a2+ r2+z2 - 2ar cos a d -3, C 2 var 1 -K2 )K - / - E Jo 3ɚ- (2.37) and since J cos a da 0 0 we have . ... 1 2)K A = - -~i)Ej + 0 (k 3) . (2.38...assumed exp(jwt) time convention. C - We begin by analyzing one of our eight secondary distribution sub- systems, as shown in Fig. D .2. V -j- Z 0j B e Vx

  8. A Bonner Sphere Spectrometer with extended response matrix

    NASA Astrophysics Data System (ADS)

    Birattari, C.; Dimovasili, E.; Mitaroff, A.; Silari, M.

    2010-08-01

    This paper describes the design, calibration and applications at high-energy accelerators of an extended-range Bonner Sphere neutron Spectrometer (BSS). The BSS was designed by the FLUKA Monte Carlo code, investigating several combinations of materials and diameters of the moderators for the high-energy channels. The system was calibrated at PTB in Braunschweig, Germany, using monoenergetic neutron beams in the energy range 144 keV-19 MeV. It was subsequently tested with Am-Be source neutrons and in the simulated workplace neutron field at CERF (the CERN-EU high-energy reference field facility). Since 2002, it has been employed for neutron spectral measurements around CERN accelerators.

  9. Optimum free energy in the reference functional approach for the integral equations theory

    NASA Astrophysics Data System (ADS)

    Ayadim, A.; Oettel, M.; Amokrane, S.

    2009-03-01

    We investigate the question of determining the bulk properties of liquids, required as input for practical applications of the density functional theory of inhomogeneous systems, using density functional theory itself. By considering the reference functional approach in the test particle limit, we derive an expression of the bulk free energy that is consistent with the closure of the Ornstein-Zernike equations in which the bridge functions are obtained from the reference system bridge functional. By examining the connection between the free energy functional and the formally exact bulk free energy, we obtain an improved expression of the corresponding non-local term in the standard reference hypernetted chain theory derived by Lado. In this way, we also clarify the meaning of the recently proposed criterion for determining the optimum hard-sphere diameter in the reference system. This leads to a theory in which the sole input is the reference system bridge functional both for the homogeneous system and the inhomogeneous one. The accuracy of this method is illustrated with the standard case of the Lennard-Jones fluid and with a Yukawa fluid with very short range attraction.

  10. USSR and Eastern Europe Scientific Abstracts, Cybernetics, Computers and Automation Technology, Number 35

    DTIC Science & Technology

    1978-09-12

    the population. Only a socialist, planned economy can cope with such problems. However, the in- creasing complexity of the tasks faced’ by...the development of systems allowing man-machine dialogue does not decrease, but rather increase the complexity of the systems involved, simply...shifting the complexity to another sphere, where it is invisible to the human utilizing the system. Figures 5; refer- ences 3: 2 Russian, 1 Western

  11. Estimated critical conditions for UO{sub 2}F{sub 2}--H{sub 2}O systems in fully water-reflected spherical geometry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jordan, W.C.; Turner, J.C.

    1992-12-01

    The purpose of this report is to document reference calculations performed using the SCALE-4.0 code system to determine the critical parameters of UO{sub 2}F{sub 2}-H{sub 2}O spheres. The calculations are an extension of those documented in ORNL/CSD/TM-284. Specifically, the data for low-enriched UO{sub 2}F{sub 2}-H{sub 2}O spheres have been extended to highly enriched uranium. These calculations, together with those reported in ORNL/CSD/TM-284, provide a consistent set of critical parameters (k{sub {infinity}}, volume, mass, mass of water) for UO{sub 2}F{sub 2} and water over the full range of enrichment and moderation ratio.

  12. Reflective all-sky thermal infrared cloud imager

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Redman, Brian J.; Shaw, Joseph A.; Nugent, Paul W.

    A reflective all-sky imaging system has been built using a long-wave infrared microbolometer camera and a reflective metal sphere. This compact system was developed for measuring spatial and temporal patterns of clouds and their optical depth in support of applications including Earth-space optical communications. The camera is mounted to the side of the reflective sphere to leave the zenith sky unobstructed. The resulting geometric distortion is removed through an angular map derived from a combination of checkerboard-target imaging, geometric ray tracing, and sun-location-based alignment. A tape of high-emissivity material on the side of the reflector acts as a reference thatmore » is used to estimate and remove thermal emission from the metal sphere. In conclusion, once a bias that is under continuing study was removed, sky radiance measurements from the all-sky imager in the 8-14 μm wavelength range agreed to within 0.91 W/(m 2 sr) of measurements from a previously calibrated, lens-based infrared cloud imager over its 110° field of view.« less

  13. Reflective all-sky thermal infrared cloud imager

    DOE PAGES

    Redman, Brian J.; Shaw, Joseph A.; Nugent, Paul W.; ...

    2018-04-17

    A reflective all-sky imaging system has been built using a long-wave infrared microbolometer camera and a reflective metal sphere. This compact system was developed for measuring spatial and temporal patterns of clouds and their optical depth in support of applications including Earth-space optical communications. The camera is mounted to the side of the reflective sphere to leave the zenith sky unobstructed. The resulting geometric distortion is removed through an angular map derived from a combination of checkerboard-target imaging, geometric ray tracing, and sun-location-based alignment. A tape of high-emissivity material on the side of the reflector acts as a reference thatmore » is used to estimate and remove thermal emission from the metal sphere. In conclusion, once a bias that is under continuing study was removed, sky radiance measurements from the all-sky imager in the 8-14 μm wavelength range agreed to within 0.91 W/(m 2 sr) of measurements from a previously calibrated, lens-based infrared cloud imager over its 110° field of view.« less

  14. The SPHERE Data Center: a reference for high contrast imaging processing

    NASA Astrophysics Data System (ADS)

    Delorme, P.; Meunier, N.; Albert, D.; Lagadec, E.; Le Coroller, H.; Galicher, R.; Mouillet, D.; Boccaletti, A.; Mesa, D.; Meunier, J.-C.; Beuzit, J.-L.; Lagrange, A.-M.; Chauvin, G.; Sapone, A.; Langlois, M.; Maire, A.-L.; Montargès, M.; Gratton, R.; Vigan, A.; Surace, C.

    2017-12-01

    The objective of the SPHERE Data Center is to optimize the scientific return of SPHERE at the VLT, by providing optimized reduction procedures, services to users and publicly available reduced data. This paper describes our motivation, the implementation of the service (partners, infrastructure and developments), services, description of the on-line data, and future developments. The SPHERE Data Center is operational and has already provided reduced data with a good reactivity to many observers. The first public reduced data have been made available in 2017. The SPHERE Data Center is gathering a strong expertise on SPHERE data and is in a very good position to propose new reduced data in the future, as well as improved reduction procedures.

  15. Directional MTF measurement using sphere phantoms for a digital breast tomosynthesis system

    NASA Astrophysics Data System (ADS)

    Lee, Changwoo; Baek, Jongduk

    2015-03-01

    The digital breast tomosynthesis (DBT) has been widely used as a diagnosis imaging modality of breast cancer because of potential for structure noise reduction, better detectability, and less breast compression. Since 3D modulation transfer function (MTF) is one of the quantitative metrics to assess the spatial resolution of medical imaging systems, it is very important to measure 3D MTF of the DBT system to evaluate the resolution performance. In order to do that, Samei et al. used sphere phantoms and applied Thornton's method to the DBT system. However, due to the limitation of Thornton's method, the low frequency drop, caused by the limited data acquisition angle and reconstruction filters, was not measured correctly. To overcome this limitation, we propose a Richardson-Lucy (RL) deconvolution based estimation method to measure the directional MTF. We reconstructed point and sphere objects using FDK algorithm within a 40⁰ data acquisition angle. The ideal 3D MTF is obtained by taking Fourier transform of the reconstructed point object, and three directions (i.e., fx-direction, fy-direction, and fxy-direction) of the ideal 3D MTF are used as a reference. To estimate the directional MTF, the plane integrals of the reconstructed and ideal sphere object were calculated and used to estimate the directional PSF using RL deconvolution technique. Finally, the directional MTF was calculated by taking Fourier transform of the estimated PSF. Compared to the previous method, the proposed method showed a good agreement with the ideal directional MTF, especially at low frequency regions.

  16. Equations of state for the fully flexible WCA chains in the fluid and solid phases based on Wertheims-TPT2

    NASA Astrophysics Data System (ADS)

    Mirzaeinia, Ali; Feyzi, Farzaneh; Hashemianzadeh, Seyed Majid

    2018-03-01

    Based on Wertheim's second order thermodynamic perturbation theory (TPT2), equations of state (EOSs) are presented for the fluid and solid phases of tangent, freely jointed spheres. It is considered that the spheres interact with each other through the Weeks-Chandler-Anderson (WCA) potential. The developed TPT2 EOS is the sum of a monomeric reference term and a perturbation contribution due to bonding. MC NVT simulations are performed to determine the structural properties of the reference system in the reduced temperature range of 0.6 ≤ T* ≤ 4.0 and the packing fraction range of 0.1 ≤ η ≤ 0.72. Mathematical functions are fitted to the simulation results of the reference system and employed in the framework of Wertheim's theory to develop TPT2 EOSs for the fluid and solid phases. The extended EOSs are compared to the MC NPT simulation results of the compressibility factor and internal energy of the fully flexible chain systems. Simulations are performed for the WCA chain system for chain lengths of up to 15 at T* = 1.0, 1.5, 2.0, 3.0. Across all the reduced temperatures, the agreement between the results of the TPT2 EOS and MC simulations is remarkable. Overall Average Absolute Relative Percent Deviation at T* = 1.0 for the compressibility factor in the entire chain lengths we covered is 0.51 and 0.77 for the solid and fluid phases, respectively. Similar features are observed in the case of residual internal energy.

  17. Equations of state for the fully flexible WCA chains in the fluid and solid phases based on Wertheims-TPT2.

    PubMed

    Mirzaeinia, Ali; Feyzi, Farzaneh; Hashemianzadeh, Seyed Majid

    2018-03-14

    Based on Wertheim's second order thermodynamic perturbation theory (TPT2), equations of state (EOSs) are presented for the fluid and solid phases of tangent, freely jointed spheres. It is considered that the spheres interact with each other through the Weeks-Chandler-Anderson (WCA) potential. The developed TPT2 EOS is the sum of a monomeric reference term and a perturbation contribution due to bonding. MC NVT simulations are performed to determine the structural properties of the reference system in the reduced temperature range of 0.6 ≤ T* ≤ 4.0 and the packing fraction range of 0.1 ≤ η ≤ 0.72. Mathematical functions are fitted to the simulation results of the reference system and employed in the framework of Wertheim's theory to develop TPT2 EOSs for the fluid and solid phases. The extended EOSs are compared to the MC NPT simulation results of the compressibility factor and internal energy of the fully flexible chain systems. Simulations are performed for the WCA chain system for chain lengths of up to 15 at T* = 1.0, 1.5, 2.0, 3.0. Across all the reduced temperatures, the agreement between the results of the TPT2 EOS and MC simulations is remarkable. Overall Average Absolute Relative Percent Deviation at T* = 1.0 for the compressibility factor in the entire chain lengths we covered is 0.51 and 0.77 for the solid and fluid phases, respectively. Similar features are observed in the case of residual internal energy.

  18. Test of simple fluid theories for the Lennard-Jones system

    NASA Astrophysics Data System (ADS)

    Malijevský, A.; Labik, S.

    1988-03-01

    A test is made of a new version of the reference-hypernetted chain approximation (RHNC) with minimized free energy proposed by Lado, Foiles and Ashcroft. An accurate relationship is used for the bridge function of the reference hard spheres. The calculated values of the compressibility factor and the internal energy are compared with simulation data, with results of the exponential approximation of Andersen et al., and with results of the Madden-Fitts approximation. The RHNC provides the most reliable results over wide ranges of reduced temperatures and densities.

  19. A new method for assessing the accuracy of full arch impressions in patients.

    PubMed

    Kuhr, F; Schmidt, A; Rehmann, P; Wöstmann, B

    2016-12-01

    To evaluate a new method of measuring the real deviation (trueness) of full arch impressions intraorally and to investigate the trueness of digital full arch impressions in comparison to a conventional impression procedure in clinical use. Four metal spheres were fixed with composite using a metal application aid to the lower teeth of 50 test subjects as reference structures. One conventional impression (Impregum Penta Soft) with subsequent type-IV gypsum model casting (CI) and three different digital impressions were performed in the lower jaw of each test person with the following intraoral scanners: Sirona CEREC Omnicam (OC), 3M True Definition (TD), Heraeus Cara TRIOS (cT). The digital and conventional (gypsum) models were analyzed relative to the spheres. Linear distance and angle measurements between the spheres, as well as digital superimpositions of the spheres with the reference data set were executed. With regard to the distance measurements, CI showed the smallest deviations followed by intraoral scanners TD, cT and OC. A digital superimposition procedure yielded the same order for the outcomes: CI (15±4μm), TD (23±9μm), cT (37±14μm), OC (214±38μm). Angle measurements revealed the smallest deviation for TD (0.06°±0,07°) followed by CI (0.07°±0.07°), cT (0.13°±0.15°) and OC (0.28°±0.21°). The new measuring method is suitable for measuring the dimensional accuracy of full arch impressions intraorally. CI is still significantly more accurate than full arch scans with intraoral scanners in clinical use. Conventional full arch impressions with polyether impression materials are still more accurate than full arch digital impressions. Digital impression systems using powder application and active wavefront sampling technology achieve the most accurate results in comparison to other intraoral scanning systems (DRKS-ID: DRKS00009360, German Clinical Trials Register). Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Application of hard sphere perturbation theory for thermodynamics of model liquid metals

    NASA Astrophysics Data System (ADS)

    Mon, K. K.

    2001-06-01

    Hard sphere perturbation theory (HSPT) has contributed toward the fundamental understanding of dense fluids for over 30 years. In recent decades, other techniques have been more popular. In this paper, we argue for the revival of hard sphere perturbation theory for the study of thermodynamics of dense liquid in general, and in liquid metal in particular. The weakness of HSPT is now well understood, and can be easily overcome by using a simple convenient Monte Carlo method to calculate the intrinsic error of HSPT free energy density. To demonstrate this approach, we consider models of liquid aluminum and sodium. We obtain the intrinsic error of HSPT with the Monte Carlo method. HSPT is shown to provide a lower free energy upper bound than one-component plasma (OCP) for alkali metals and polyvalent metals. We are thus able to provide insight into the long standing observation that a OCP is a better reference system than a HS for alkali metals.

  1. DynamO: a free O(N) general event-driven molecular dynamics simulator.

    PubMed

    Bannerman, M N; Sargant, R; Lue, L

    2011-11-30

    Molecular dynamics algorithms for systems of particles interacting through discrete or "hard" potentials are fundamentally different to the methods for continuous or "soft" potential systems. Although many software packages have been developed for continuous potential systems, software for discrete potential systems based on event-driven algorithms are relatively scarce and specialized. We present DynamO, a general event-driven simulation package, which displays the optimal O(N) asymptotic scaling of the computational cost with the number of particles N, rather than the O(N) scaling found in most standard algorithms. DynamO provides reference implementations of the best available event-driven algorithms. These techniques allow the rapid simulation of both complex and large (>10(6) particles) systems for long times. The performance of the program is benchmarked for elastic hard sphere systems, homogeneous cooling and sheared inelastic hard spheres, and equilibrium Lennard-Jones fluids. This software and its documentation are distributed under the GNU General Public license and can be freely downloaded from http://marcusbannerman.co.uk/dynamo. Copyright © 2011 Wiley Periodicals, Inc.

  2. Panoramic stereo sphere vision

    NASA Astrophysics Data System (ADS)

    Feng, Weijia; Zhang, Baofeng; Röning, Juha; Zong, Xiaoning; Yi, Tian

    2013-01-01

    Conventional stereo vision systems have a small field of view (FOV) which limits their usefulness for certain applications. While panorama vision is able to "see" in all directions of the observation space, scene depth information is missed because of the mapping from 3D reference coordinates to 2D panoramic image. In this paper, we present an innovative vision system which builds by a special combined fish-eye lenses module, and is capable of producing 3D coordinate information from the whole global observation space and acquiring no blind area 360°×360° panoramic image simultaneously just using single vision equipment with one time static shooting. It is called Panoramic Stereo Sphere Vision (PSSV). We proposed the geometric model, mathematic model and parameters calibration method in this paper. Specifically, video surveillance, robotic autonomous navigation, virtual reality, driving assistance, multiple maneuvering target tracking, automatic mapping of environments and attitude estimation are some of the applications which will benefit from PSSV.

  3. Multifunctional Inflatable Structure Being Developed for the PowerSphere Concept

    NASA Technical Reports Server (NTRS)

    Peterson, Todd T.

    2004-01-01

    NASA has funded a collaborative team of The Aerospace Corporation, ILC Dover, Lockheed Martin, and NASA Glenn Research Center to develop the Multifunctional Inflatable Structure (MIS) for a "PowerSphere" concept through a NASA Research Announcement. This power system concept has several advantages, including a high collection area, low weight and stowage volume, and the elimination of all solar array pointing mechanisms. The current 3-year effort will culminate with the fabrication and testing of a fully functional engineering development unit. The baseline design of the Power-Sphere consists of two opposing semispherical domes connected to a central spacecraft. Each semispherical dome consists of hexagonal and pentagonal solar cell panels that together form a geodetic sphere. Inflatable ultraviolet (UV) rigidizable tubular hinges between the solar cell panels and UV rigidizable isogrid center columns with imbedded flex circuitry form the MIS. The reference configuration for the PowerSphere is a 0.6-m-diameter (fully deployed) spacecraft with a total mass budget of 4 kg (1 kg for PowerSphere, 3 kg for spacecraft) capable of producing 29 W of electricity with 10-percent-efficient thin-film solar cells. In a stowed configuration, the solar cell panels will be folded sequentially to the outside of the instrument decks. The center column will be z-folded between the instrument decks and the spacecraft housing for packaging. The instrument panel will secure the z-folded stack with launch ties. After launch, once the release tie is triggered, the center column and hinge tubes will inflate and be rigidized in their final configurations by ultraviolet radiation. The overall PowerSphere deployment sequence is shown pictorially in the following illustration.

  4. An intersecting chord method for minimum circumscribed sphere and maximum inscribed sphere evaluations of sphericity error

    NASA Astrophysics Data System (ADS)

    Liu, Fei; Xu, Guanghua; Zhang, Qing; Liang, Lin; Liu, Dan

    2015-11-01

    As one of the Geometrical Product Specifications that are widely applied in industrial manufacturing and measurement, sphericity error can synthetically scale a 3D structure and reflects the machining quality of a spherical workpiece. Following increasing demands in the high motion performance of spherical parts, sphericity error is becoming an indispensable component in the evaluation of form error. However, the evaluation of sphericity error is still considered to be a complex mathematical issue, and the related research studies on the development of available models are lacking. In this paper, an intersecting chord method is first proposed to solve the minimum circumscribed sphere and maximum inscribed sphere evaluations of sphericity error. This new modelling method leverages chord relationships to replace the characteristic points, thereby significantly reducing the computational complexity and improving the computational efficiency. Using the intersecting chords to generate a virtual centre, the reference sphere in two concentric spheres is simplified as a space intersecting structure. The position of the virtual centre on the space intersecting structure is determined by characteristic chords, which may reduce the deviation between the virtual centre and the centre of the reference sphere. In addition,two experiments are used to verify the effectiveness of the proposed method with real datasets from the Cartesian coordinates. The results indicate that the estimated errors are in perfect agreement with those of the published methods. Meanwhile, the computational efficiency is improved. For the evaluation of the sphericity error, the use of high performance computing is a remarkable change.

  5. Autonomy and Pluralism in the Education System: A Case Study of Spanish Public Schools in the International Context

    ERIC Educational Resources Information Center

    Sancho Gargallo, Miguel Angel

    2013-01-01

    As governments strive to improve outcomes in education, and respond to the needs of an ever more diverse population, autonomy has gained increased prominence in national and international spheres. In the context of education, autonomy refers to the decision-making capacity of a school, and to the manner and areas over which those decisions can be…

  6. Thermodynamics of Thomas-Fermi screened Coulomb systems

    NASA Technical Reports Server (NTRS)

    Firey, B.; Ashcroft, N. W.

    1977-01-01

    We obtain in closed analytic form, estimates for the thermodynamic properties of classical fluids with pair potentials of Yukawa type, with special reference to dense fully ionized plasmas with Thomas-Fermi or Debye-Hueckel screening. We further generalize the hard-sphere perturbative approach used for similarly screened two-component mixtures, and demonstrate phase separation in this simple model of a liquid mixture of metallic helium and hydrogen.

  7. Structure and thermodynamics of a mixture of patchy and spherical colloids: A multi-body association theory with complete reference fluid information

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bansal, Artee; Asthagiri, D.; Cox, Kenneth R.

    A mixture of solvent particles with short-range, directional interactions and solute particles with short-range, isotropic interactions that can bond multiple times is of fundamental interest in understanding liquids and colloidal mixtures. Because of multi-body correlations, predicting the structure and thermodynamics of such systems remains a challenge. Earlier Marshall and Chapman [J. Chem. Phys. 139, 104904 (2013)] developed a theory wherein association effects due to interactions multiply the partition function for clustering of particles in a reference hard-sphere system. The multi-body effects are incorporated in the clustering process, which in their work was obtained in the absence of the bulk medium.more » The bulk solvent effects were then modeled approximately within a second order perturbation approach. However, their approach is inadequate at high densities and for large association strengths. Based on the idea that the clustering of solvent in a defined coordination volume around the solute is related to occupancy statistics in that defined coordination volume, we develop an approach to incorporate the complete information about hard-sphere clustering in a bulk solvent at the density of interest. The occupancy probabilities are obtained from enhanced sampling simulations but we also develop a concise parametric form to model these probabilities using the quasichemical theory of solutions. We show that incorporating the complete reference information results in an approach that can predict the bonding state and thermodynamics of the colloidal solute for a wide range of system conditions.« less

  8. A new method for registration of heterogeneous sensors in a dimensional measurement system

    NASA Astrophysics Data System (ADS)

    Zhao, Yan; Wang, Zhong; Fu, Luhua; Qu, Xinghua; Zhang, Heng; Liu, Changjie

    2017-10-01

    Registration of multiple sensors is a basic step in multi-sensor dimensional or coordinate measuring systems before any measurement. In most cases, a common standard is used to be measured by all sensors, and this may work well for general registration of multiple homogeneous sensors. However, when inhomogeneous sensors detect a common standard, it is usually very difficult to obtain the same information, because of the different working principles of the sensors. In this paper, a new method called multiple steps registration is proposed to register two sensors: a video camera sensor (VCS) and a tactile probe sensor (TPS). In this method, the two sensors measure two separated standards: a chrome circle on a reticle and a reference sphere with a constant distance between them, fixed on a steel plate. The VCS captures only the circle and the TPS touches only the sphere. Both simulations and real experiments demonstrate that the proposed method is robust and accurate in the registration of multiple inhomogeneous sensors in a dimensional measurement system.

  9. Scattering characteristics of relativistically moving concentrically layered spheres

    NASA Astrophysics Data System (ADS)

    Garner, Timothy J.; Lakhtakia, Akhlesh; Breakall, James K.; Bohren, Craig F.

    2018-02-01

    The energy extinction cross section of a concentrically layered sphere varies with velocity as the Doppler shift moves the spectral content of the incident signal in the sphere's co-moving inertial reference frame toward or away from resonances of the sphere. Computations for hollow gold nanospheres show that the energy extinction cross section is high when the Doppler shift moves the incident signal's spectral content in the co-moving frame near the wavelength of the sphere's localized surface plasmon resonance. The energy extinction cross section of a three-layer sphere consisting of an olivine-silicate core surrounded by a porous and a magnetite layer, which is used to explain extinction caused by interstellar dust, also depends strongly on velocity. For this sphere, computations show that the energy extinction cross section is high when the Doppler shift moves the spectral content of the incident signal near either of olivine-silicate's two localized surface phonon resonances at 9.7 μm and 18 μm.

  10. The effect of ultrasound irradiation on the convective heat transfer rate during immersion cooling of a stationary sphere.

    PubMed

    Kiani, Hossein; Sun, Da-Wen; Zhang, Zhihang

    2012-11-01

    It has been proven that ultrasound irradiation can enhance the rate of heat transfer processes. The objective of this work was to study the heat transfer phenomenon, mainly the heat exchange at the surface, as affected by ultrasound irradiation around a stationary copper sphere (k=386W m(-1)K(-1), C(p)=384J kg(-1)K(-1), ρ=8660kg m(-3)) during cooling. The sphere (0.01m in diameter) was immersed in an ethylene glycol-water mixture (-10°C) in an ultrasonic cooling system that included a refrigerated circulator, a flow meter, an ultrasound generator and an ultrasonic bath. The temperature of the sphere was recorded using a data logger equipped with a T-type thermocouple in the center of the sphere. The temperature of the cooling medium was also monitored by four thermocouples situated at different places in the bath. The sphere was located at different positions (0.02, 0.04 and 0.06m) above the transducer surface of the bath calculated considering the center of the sphere as the center of the reference system and was exposed to different intensities of ultrasound (0, 120, 190, 450, 890, 1800, 2800, 3400 and 4100W m(-2)) during cooling. The frequency of the ultrasound was 25kHz. It was demonstrated that ultrasound irradiation can increase the rate of heat transfer significantly, resulting in considerably shorter cooling times. Higher intensities caused higher cooling rates, and Nu values were increased from about 23-27 to 25-108 depending on the intensity of ultrasound and the position of the sphere. However, high intensities of ultrasound led to the generation of heat at the surface of the sphere, thus limiting the lowest final temperature achieved. An analytical solution was developed considering the heat generation and was fitted to the experimental data with R(2) values in the range of 0.910-0.998. Visual observations revealed that both cavitation and acoustic streaming were important for heat transfer phenomenon. Cavitation clouds at the surface of the sphere were the main cause of heating effect. The results showed that closer distances to the transducer surface showed higher cooling rates. On the other hand, despite having a bigger distance from the transducer, when the sphere was located close to the gas-liquid interface the enhancement factor of heat transfer was higher. Ultrasound irradiation showed promising effect for the enhancement of convective heat transfer rate during immersion cooling. More investigations are required to demonstrate the behavior of ultrasound assisted heat transfer and resolve the proper way of the application of ultrasound to assist the cooling and/or freezing processes. Copyright © 2012 Elsevier B.V. All rights reserved.

  11. Results of Absolute Cavity Pyrgeometer (ACP), InfraRed Integrating Sphere (IRIS), and Atmospheric Emitted Radiance Interferometer (AERI) Comparisons and CIMO Recommendations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reda, Ibrahim M; Dooraghi, Michael R; Sengupta, Manajit

    Presenting results of five comparisons between ACPs and IRISs and the difference between the longwave irradiance measured by the ACPs and IRISs versus the average irradiance measured by the WISG. The process of CIMO recommendation to establish the world reference for measuring the atmospheric longwave irradiance with traceability to the International System of Units (SI) is also presented.

  12. Benchmark radar targets for the validation of computational electromagnetics programs

    NASA Technical Reports Server (NTRS)

    Woo, Alex C.; Wang, Helen T. G.; Schuh, Michael J.; Sanders, Michael L.

    1993-01-01

    Results are presented of a set of computational electromagnetics validation measurements referring to three-dimensional perfectly conducting smooth targets, performed for the Electromagnetic Code Consortium. Plots are presented for both the low- and high-frequency measurements of the NASA almond, an ogive, a double ogive, a cone-sphere, and a cone-sphere with a gap.

  13. Communications/Navigation Outage Forecasting System (C/NOFS)

    DTIC Science & Technology

    2010-02-21

    al., 2002]. They are also lower than values predicted by the International Reference Iono- sphere ( IRI ) model [Gulyaeva and Titheridge, 2006] run for...based on the IRI model or other observations. At present no mechanism has been proposed which accounts for the basic formation of BPDs or their...funding by the DMSP program office. We thank J. Retterer for the IRI model results. This research was supported by Air Force Office of Scientific Research

  14. The Microwave Anisotropy Probe (MAP) Attitude Control System

    NASA Technical Reports Server (NTRS)

    Markley, F. Landis; Andrews, Stephen F.; ODonnell, James R., Jr.; Ward, David K.; Ericsson, Aprille J.; Bauer, Frank H. (Technical Monitor)

    2002-01-01

    The Microwave Anisotropy Probe mission is designed to produce a map of the cosmic microwave background radiation over the entire celestial sphere by executing a fast spin and a slow precession of its spin axis about the Sun line to obtain a highly interconnected set of measurements. The spacecraft attitude is sensed and controlled using an Inertial Reference Unit, two Autonomous Star Trackers, a Digital Sun Sensor, twelve Coarse Sun Sensors, three Reaction Wheel Assemblies, and a propulsion system. This paper describes the design of the attitude control system that carries out this mission and presents some early flight experience.

  15. Molecular-scale hydrophobic interactions between hard-sphere reference solutes are attractive and endothermic.

    PubMed

    Chaudhari, Mangesh I; Holleran, Sinead A; Ashbaugh, Henry S; Pratt, Lawrence R

    2013-12-17

    The osmotic second virial coefficients, B2, for atomic-sized hard spheres in water are attractive (B2 < 0) and become more attractive with increasing temperature (ΔB2/ΔT < 0) in the temperature range 300 K ≤ T ≤ 360 K. Thus, these hydrophobic interactions are attractive and endothermic at moderate temperatures. Hydrophobic interactions between atomic-sized hard spheres in water are more attractive than predicted by the available statistical mechanical theory. These results constitute an initial step toward detailed molecular theory of additional intermolecular interaction features, specifically, attractive interactions associated with hydrophobic solutes.

  16. Precision alignment and calibration of optical systems using computer generated holograms

    NASA Astrophysics Data System (ADS)

    Coyle, Laura Elizabeth

    As techniques for manufacturing and metrology advance, optical systems are being designed with more complexity than ever before. Given these prescriptions, alignment and calibration can be a limiting factor in their final performance. Computer generated holograms (CGHs) have several unique properties that make them powerful tools for meeting these demanding tolerances. This work will present three novel methods for alignment and calibration of optical systems using computer generated holograms. Alignment methods using CGHs require that the optical wavefront created by the CGH be related to a mechanical datum to locate it space. An overview of existing methods is provided as background, then two new alignment methods are discussed in detail. In the first method, the CGH contact Ball Alignment Tool (CBAT) is used to align a ball or sphere mounted retroreflector (SMR) to a Fresnel zone plate pattern with micron level accuracy. The ball is bonded directly onto the CGH substrate and provides permanent, accurate registration between the optical wavefront and a mechanical reference to locate the CGH in space. A prototype CBAT was built and used to align and bond an SMR to a CGH. In the second method, CGH references are used to align axi-symmetric optics in four degrees of freedom with low uncertainty and real time feedback. The CGHs create simultaneous 3D optical references where the zero order reflection sets tilt and the first diffracted order sets centration. The flexibility of the CGH design can be used to accommodate a wide variety of optical systems and maximize sensitivity to misalignments. A 2-CGH prototype system was aligned multiplied times and the alignment uncertainty was quantified and compared to an error model. Finally, an enhanced calibration method is presented. It uses multiple perturbed measurements of a master sphere to improve the calibration of CGH-based Fizeau interferometers ultimately measuring aspheric test surfaces. The improvement in the calibration is a function of the interferometer error and the aspheric departure of the desired test surface. This calibration is most effective at reducing coma and trefoil from figure error or misalignments of the interferometer components. The enhanced calibration can reduce overall measurement uncertainty or allow the budgeted error contribution from another source to be increased. A single set of sphere measurements can be used to calculate calibration maps for closely related aspheres, including segmented primary mirrors for telescopes. A parametric model is developed and compared to the simulated calibration of a case study interferometer.

  17. On the phase behavior of hard aspherical particles

    NASA Astrophysics Data System (ADS)

    Miller, William L.; Cacciuto, Angelo

    2010-12-01

    We use numerical simulations to understand how random deviations from the ideal spherical shape affect the ability of hard particles to form fcc crystalline structures. Using a system of hard spheres as a reference, we determine the fluid-solid coexistence pressures of both shape-polydisperse and monodisperse systems of aspherical hard particles. We find that when particles are sufficiently isotropic, the coexistence pressure can be predicted from a linear relation involving the product of two simple geometric parameters characterizing the asphericity of the particles. Finally, our results allow us to gain direct insight into the crystallizability limits of these systems by rationalizing empirical data obtained for analogous monodisperse systems.

  18. Sphere based fluid systems

    NASA Technical Reports Server (NTRS)

    Elleman, Daniel D. (Inventor); Wang, Taylor G. (Inventor)

    1989-01-01

    Systems are described for using multiple closely-packed spheres. In one system for passing fluid, a multiplicity of spheres lie within a container, with all of the spheres having the same outside diameter and with the spheres being closely nested in one another to create multiple interstitial passages of a known size and configuration and smooth walls. The container has an inlet and outlet for passing fluid through the interstitial passages formed between the nested spheres. The small interstitial passages can be used to filter out material, especially biological material such as cells in a fluid, where the cells can be easily destroyed if passed across sharp edges. The outer surface of the spheres can contain a material that absorbs a constitutent in the flowing fluid, such as a particular contamination gas, or can contain a catalyst to chemically react the fluid passing therethrough, the use of multiple small spheres assuring a large area of contact of these surfaces of the spheres with the fluid. In a system for storing and releasing a fluid such as hydrogen as a fuel, the spheres can include a hollow shell containing the fluid to be stored, and located within a compressable container that can be compressed to break the shells and release the stored fluid.

  19. Provision of Exact Formulations for the "Forward Scattering of a Gaussian Beam by a Nonabsorbing Sphere": Comment

    NASA Technical Reports Server (NTRS)

    Pogorzelski, Ronald J.

    1995-01-01

    The purpose of an earlier publication [Appl. Opt. 34, 2120 (1995)], to provide an exact formulation of the scattering of beamlike radiation fields from spheres, is clarified and its relation to the treatment of this subject in two more recent publications is described. Also, an error in the reference list in the earlier publication is rectified.

  20. Standard Reference Material (SRM 1990) for Single Crystal Diffractometer Alignment

    USGS Publications Warehouse

    Wong-Ng, W.; Siegrist, T.; DeTitta, G.T.; Finger, L.W.; Evans, H.T.; Gabe, E.J.; Enright, G.D.; Armstrong, J.T.; Levenson, M.; Cook, L.P.; Hubbard, C.R.

    2001-01-01

    An international project was successfully completed which involved two major undertakings: (1) a round-robin to demonstrate the viability of the selected standard and (2) the certification of the lattice parameters of the SRM 1990, a Standard Reference Material?? for single crystal diffractometer alignment. This SRM is a set of ???3500 units of Cr-doped Al2O3, or ruby spheres [(0 420.011 mole fraction % Cr (expanded uncertainty)]. The round-robin consisted of determination of lattice parameters of a pair of crystals' the ruby sphere as a standard, and a zeolite reference to serve as an unknown. Fifty pairs of crystals were dispatched from Hauptman-Woodward Medical Research Institute to volunteers in x-ray laboratories world-wide. A total of 45 sets of data was received from 32 laboratories. The mean unit cell parameters of the ruby spheres was found to be a=4.7608 A?? ?? 0.0062 A??, and c=12.9979 A?? ?? 0.020 A?? (95 % intervals of the laboratory means). The source of errors of outlier data was identified. The SRM project involved the certification of lattice parameters using four well-aligned single crystal diffractometers at (Bell Laboratories) Lucent Technologies and at NRC of Canada (39 ruby spheres), the quantification of the Cr content using a combined microprobe and SEM/EDS technique, and the evaluation of the mosaicity of the ruby spheres using a double-crystal spectrometry method. A confirmation of the lattice parameters was also conducted using a Guinier-Ha??gg camera. Systematic corrections of thermal expansion and refraction corrections were applied. These rubies_ are rhombohedral, with space group R3c. The certified mean unit cell parameters are a=4.76080 ?? 0.00029 A??, and c=12 99568 A?? ?? 0.00087 A?? (expanded uncertainty). These certified lattice parameters fall well within the results of those obtained from the international round-robin study. The Guinier-Ha??gg transmission measurements on five samples of powdered rubies (a=4.7610 A?? ?? 0.0013 A??, and c=12.9954 A?? ?? 0.0034 A??) agreed well with the values obtained from the single crystal spheres.

  1. Standard Reference Material (SRM 1990) For Single Crystal Diffractometer Alignment

    PubMed Central

    Wong-Ng, W.; Siegrist, T.; DeTitta, G. T.; Finger, L. W.; Evans, H. T.; Gabe, E. J.; Enright, G. D.; Armstrong, J. T.; Levenson, M.; Cook, L. P.; Hubbard, C. R.

    2001-01-01

    An international project was successfully completed which involved two major undertakings: (1) a round-robin to demonstrate the viability of the selected standard and (2) the certification of the lattice parameters of the SRM 1990, a Standard Reference Material® for single crystal diffractometer alignment. This SRM is a set of ≈3500 units of Cr-doped Al2O3, or ruby spheres [(0.420.011 mole fraction % Cr (expanded uncertainty)]. The round-robin consisted of determination of lattice parameters of a pair of crystals: the ruby sphere as a standard, and a zeolite reference to serve as an unknown. Fifty pairs of crystals were dispatched from Hauptman-Woodward Medical Research Institute to volunteers in x-ray laboratories world-wide. A total of 45 sets of data was received from 32 laboratories. The mean unit cell parameters of the ruby spheres was found to be a=4.7608 ű0.0062 Å, and c=12.9979 ű0.020 Å (95 % intervals of the laboratory means). The source of errors of outlier data was identified. The SRM project involved the certification of lattice parameters using four well-aligned single crystal diffractometers at (Bell Laboratories) Lucent Technologies and at NRC of Canada (39 ruby spheres), the quantification of the Cr content using a combined microprobe and SEM/EDS technique, and the evaluation of the mosaicity of the ruby spheres using a double-crystal spectrometry method. A confirmation of the lattice parameters was also conducted using a Guinier-Hägg camera. Systematic corrections of thermal expansion and refraction corrections were applied. These rubies– are rhombohedral, with space group R3¯c. The certified mean unit cell parameters are a=4.76080±0.00029 Å, and c=12.99568 ű0.00087 Å (expanded uncertainty). These certified lattice parameters fall well within the results of those obtained from the international round-robin study. The Guinier-Hägg transmission measurements on five samples of powdered rubies (a=4.7610 ű0.0013 Å, and c = 12.9954 ű0.0034 Å) agreed well with the values obtained from the single crystal spheres. PMID:27500067

  2. Topography measurements of high NA aspherical microlenses by digital holographic microscopy with spherical illumination

    NASA Astrophysics Data System (ADS)

    Józwik, Michal; Mikuła, Marta; Kozacki, Tomasz; Kostencka, Julianna; Gorecki, Christophe

    2017-06-01

    In this contribution, we propose a method of digital holographic microscopy (DHM) that enables measurement of high numerical aperture spherical and aspherical microstructures of both concave and convex shapes. The proposed method utilizes reflection of the spherical illumination beam from the object surface and the interference with a spherical reference beam of the similar curvature. In this case, the NA of DHM is fully utilized for illumination and imaging of the reflected object beam. Thus, the system allows capturing the phase coming from larger areas of the quasi-spherical object and, therefore, offers possibility of high accuracy characterization of its surface even in the areas of high inclination. The proposed measurement procedure allows determining all parameters required for the accurate shape recovery: the location of the object focus point and the positions of the illumination and reference point sources. The utility of the method is demonstrated with characterization of surface of high NA focusing objects. The accuracy is firstly verified by characterization of a known reference sphere with low error of sphericity. Then, the method is applied for shape measurement of spherical and aspheric microlenses. The results provide a full-field reconstruction of high NA topography with resolution in the nanometer range. The surface sphericity is evaluated by the deviation from the best fitted sphere or asphere, and the important parameters of the measured microlens: e.g.: radius of curvature and conic constant.

  3. Demixing in simple dipolar mixtures: Integral equation versus density functional results

    NASA Astrophysics Data System (ADS)

    Range, Gabriel M.; Klapp, Sabine H. L.

    2004-09-01

    Using reference hypernetted chain (RHNC) integral equations and density functional theory in the modified mean-field (MMF) approximation we investigate the phase behavior of binary mixtures of dipolar hard spheres. The two species ( A and B ) differ only in their dipole moments mA and mB , and the central question investigated is under which conditions these asymmetric mixtures can exhibit demixing phase transitions in the fluid phase regime. Results from our two theoretical approaches turn out to strongly differ. Within the RHNC (which we apply to the isotropic high-temperature phase) demixing does indeed occur for dense systems with small interaction parameters Γ=mB2/mA2 . This result generalizes previously reported observations on demixing in mixtures of dipolar and neutral hard spheres (Γ=0) to the case of true dipolar hard sphere mixtures. The RHNC approach also indicates that these demixed fluid phases are isotropic at temperatures accessible by the theory, whereas isotropic-to-ferroelectric transitions occur only at larger Γ . The MMF theory, on the other hand, yields a different picture in which demixing occurs in combination with spontaneous ferroelectricity at all Γ considered. This discrepancy underlines the relevance of correlational effects for the existence of demixing transitions in dipolar systems without dispersive interactions. Indeed, supplementing the dipolar interactions by small, asymmetric amounts of van der Waals-like interactions (and thereby supporting the systems tendency to demix) one finally reaches good agreement between MMF and RHNC results.

  4. Measurement of steep aspheric surfaces using improved two-wavelength phase-shifting interferometer

    NASA Astrophysics Data System (ADS)

    Zhang, Liqiong; Wang, Shaopu; Hu, Yao; Hao, Qun

    2017-10-01

    Optical components with aspheric surfaces can improve the imaging quality of optical systems, and also provide extra advantages such as lighter weight, smaller volume and simper structure. In order to satisfy these performance requirements, the surface error of aspheric surfaces, especially high departure aspheric surfaces must be measured accurately and conveniently. The major obstacle of traditional null-interferometry for aspheric surface under test is that specific and complex null optics need to be designed to fully compensate for the normal aberration of the aspheric surface under test. However, non-null interferometry partially compensating for the aspheric normal aberration can test aspheric surfaces without specific null optics. In this work, a novel non-null test approach of measuring the deviation between aspheric surfaces and the best reference sphere by using improved two-wavelength phase shifting interferometer is described. With the help of the calibration based on reverse iteration optimization, we can effectively remove the retrace error and thus improve the accuracy. Simulation results demonstrate that this method can measure the aspheric surface with the departure of over tens of microns from the best reference sphere, which introduces approximately 500λ of wavefront aberration at the detector.

  5. Free energy and internal energy of electron-screened plasmas in a modified hypernetted-chain approximation

    NASA Astrophysics Data System (ADS)

    Perrot, F.

    1991-12-01

    We report results of Helmholtz-free-energy and internal-energy calculations using the modified hypernetted-chain (MHNC) equation method, in the formulation of Lado, Foiles, and Ashcroft [Phys. Rev. A 28, 2374 (1983)], for a model plasma of ions linearly screened by electrons. The results are compared with HNC calculations (no Bridge term), with variational calculations using a hard-spheres reference system, and with a numerical fit of Monte Carlo simulations.

  6. Individualized adjustments to reference phantom internal organ dosimetry—scaling factors given knowledge of patient internal anatomy

    NASA Astrophysics Data System (ADS)

    Wayson, Michael B.; Bolch, Wesley E.

    2018-04-01

    Various computational tools are currently available that facilitate patient organ dosimetry in diagnostic nuclear medicine, yet they are typically restricted to reporting organ doses to ICRP-defined reference phantoms. The present study, while remaining computational phantom based, provides straightforward tools to adjust reference phantom organ dose for both internal photon and electron sources. A wide variety of monoenergetic specific absorbed fractions were computed using radiation transport simulations for tissue spheres of varying size and separation distance. Scaling methods were then constructed for both photon and electron self-dose and cross-dose, with data validation provided from patient-specific voxel phantom simulations, as well as via comparison to the scaling methodology given in MIRD Pamphlet No. 11. Photon and electron self-dose was found to be dependent on both radiation energy and sphere size. Photon cross-dose was found to be mostly independent of sphere size. Electron cross-dose was found to be dependent on sphere size when the spheres were in close proximity, owing to differences in electron range. The validation studies showed that this dataset was more effective than the MIRD 11 method at predicting patient-specific photon doses for at both high and low energies, but gave similar results at photon energies between 100 keV and 1 MeV. The MIRD 11 method for electron self-dose scaling was accurate for lower energies but began to break down at higher energies. The photon cross-dose scaling methodology developed in this study showed gains in accuracy of up to 9% for actual patient studies, and the electron cross-dose scaling methodology showed gains in accuracy up to 9% as well when only the bremsstrahlung component of the cross-dose was scaled. These dose scaling methods are readily available for incorporation into internal dosimetry software for diagnostic phantom-based organ dosimetry.

  7. Individualized adjustments to reference phantom internal organ dosimetry-scaling factors given knowledge of patient internal anatomy.

    PubMed

    Wayson, Michael B; Bolch, Wesley E

    2018-04-13

    Various computational tools are currently available that facilitate patient organ dosimetry in diagnostic nuclear medicine, yet they are typically restricted to reporting organ doses to ICRP-defined reference phantoms. The present study, while remaining computational phantom based, provides straightforward tools to adjust reference phantom organ dose for both internal photon and electron sources. A wide variety of monoenergetic specific absorbed fractions were computed using radiation transport simulations for tissue spheres of varying size and separation distance. Scaling methods were then constructed for both photon and electron self-dose and cross-dose, with data validation provided from patient-specific voxel phantom simulations, as well as via comparison to the scaling methodology given in MIRD Pamphlet No. 11. Photon and electron self-dose was found to be dependent on both radiation energy and sphere size. Photon cross-dose was found to be mostly independent of sphere size. Electron cross-dose was found to be dependent on sphere size when the spheres were in close proximity, owing to differences in electron range. The validation studies showed that this dataset was more effective than the MIRD 11 method at predicting patient-specific photon doses for at both high and low energies, but gave similar results at photon energies between 100 keV and 1 MeV. The MIRD 11 method for electron self-dose scaling was accurate for lower energies but began to break down at higher energies. The photon cross-dose scaling methodology developed in this study showed gains in accuracy of up to 9% for actual patient studies, and the electron cross-dose scaling methodology showed gains in accuracy up to 9% as well when only the bremsstrahlung component of the cross-dose was scaled. These dose scaling methods are readily available for incorporation into internal dosimetry software for diagnostic phantom-based organ dosimetry.

  8. Thermodynamic properties of non-conformal soft-sphere fluids with effective hard-sphere diameters.

    PubMed

    Rodríguez-López, Tonalli; del Río, Fernando

    2012-01-28

    In this work we study a set of soft-sphere systems characterised by a well-defined variation of their softness. These systems represent an extension of the repulsive Lennard-Jones potential widely used in statistical mechanics of fluids. This type of soft spheres is of interest because they represent quite accurately the effective intermolecular repulsion in fluid substances and also because they exhibit interesting properties. The thermodynamics of the soft-sphere fluids is obtained via an effective hard-sphere diameter approach that leads to a compact and accurate equation of state. The virial coefficients of soft spheres are shown to follow quite simple relationships that are incorporated into the equation of state. The approach followed exhibits the rescaling of the density that produces a unique equation for all systems and temperatures. The scaling is carried through to the level of the structure of the fluids.

  9. Fundamental measure theory for the inhomogeneous hard-sphere system based on Santos' consistent free energy.

    PubMed

    Hansen-Goos, Hendrik; Mortazavifar, Mostafa; Oettel, Martin; Roth, Roland

    2015-05-01

    Based on Santos' general solution for the scaled-particle differential equation [Phys. Rev. E 86, 040102(R) (2012)], we construct a free-energy functional for the hard-sphere system. The functional is obtained by a suitable generalization and extension of the set of scaled-particle variables using the weighted densities from Rosenfeld's fundamental measure theory for the hard-sphere mixture [Phys. Rev. Lett. 63, 980 (1989)]. While our general result applies to the hard-sphere mixture, we specify remaining degrees of freedom by requiring the functional to comply with known properties of the pure hard-sphere system. Both for mixtures and pure systems, the functional can be systematically extended following the lines of our derivation. We test the resulting functionals regarding their behavior upon dimensional reduction of the fluid as well as their ability to accurately describe the hard-sphere crystal and the liquid-solid transition.

  10. The Microwave Anisotropy Probe (MAP) Mission

    NASA Technical Reports Server (NTRS)

    Markley, F. Landis; Andrews, Stephen F.; ODonnell, James R., Jr.; Ward, David K.; Bauer, Frank H. (Technical Monitor)

    2002-01-01

    The Microwave Anisotropy Probe mission is designed to produce a map of the cosmic microwave background radiation over the entire celestial sphere by executing a fast spin and a slow precession of its spin axis about the Sun line to obtain a highly interconnected set of measurements. The spacecraft attitude is sensed and controlled using an inertial reference unit, two star trackers, a digital sun sensor, twelve coarse sun sensors, three reaction wheel assemblies, and a propulsion system. This paper presents an overview of the design of the attitude control system to carry out this mission and presents some early flight experience.

  11. The Microwave Anisotropy Probe (MAP) Mission

    NASA Technical Reports Server (NTRS)

    Markley, F. Landis; Andrews, Stephen F.; ODonnell, James R., Jr.; Ward, David K.; Ericsson, Aprille J.; Bauer, Frank H. (Technical Monitor)

    2002-01-01

    The Microwave Anisotropy Probe mission is designed to produce a map of the cosmic microwave background radiation over the entire celestial sphere by executing a fast spin and a slow precession of its spin axis about the Sun line to obtain a highly interconnected set of measurements. The spacecraft attitude is sensed and controlled using an Inertial Reference Unit, two Autonomous Star Trackers, a Digital Sun Sensor, twelve Coarse Sun Sensors, three Reaction Wheel Assemblies, and a propulsion system. This paper describes the design of the attitude control system that carries out this mission and presents some early flight experience.

  12. Discovery of a Frank-Kasper [sigma] Phase in Sphere-Forming Block Copolymer Melts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, Sangwoo; Bluemle, Michael J.; Bates, Frank S.

    Sphere-forming block copolymers are known to self-assemble into body-centered cubic crystals near the order-disorder transition temperature. Small-angle x-ray scattering and transmission electron microscopy experiments on diblock and tetrablock copolymer melts have revealed an equilibrium phase characterized by a large tetragonal unit cell containing 30 microphase-separated spheres. This structure, referred to as the sigma ({sigma}) phase by Frank and Kasper more than 50 years ago, nucleates and grows from the body-centered cubic phase similar to its occurrence in metal alloys and is a crystal approximant to dodecagonal quasicrystals. Formation of the {sigma} phase in undiluted linear block copolymers (and certain branchedmore » dendrimers) appears to be mediated by macromolecular packing frustration, an entropic contribution to the interparticle interactions that control the sphere-packing geometry.« less

  13. Thermodynamical properties of liquid lanthanides-A variational approach

    NASA Astrophysics Data System (ADS)

    Patel, H. P.; Thakor, P. B.; Sonvane, Y. A.

    2015-06-01

    Thermodynamical properties like Entropy (S), Internal energy (E) and Helmholtz free energy (F) of liquid lanthanides using a variation principle based on the Gibbs-Bogoliubuv (GB) inequality with Percus Yevick hard sphere reference system have been reported in the present investigation. To describe electron-ion interaction we have used our newly constructed parameter free model potential along with Sarkar et al. local field correction function. Lastly, we conclude that our newly constructed model potential is capable to explain the thermodynamical properties of liquid lanthanides.

  14. Thermodynamical properties of liquid lanthanides-A variational approach

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Patel, H. P.; Department of Applied Physics, S. V. National Institute of Technology, Surat 395 007, Gujarat; Thakor, P. B., E-mail: pbthakor@rediffmail.com

    2015-06-24

    Thermodynamical properties like Entropy (S), Internal energy (E) and Helmholtz free energy (F) of liquid lanthanides using a variation principle based on the Gibbs-Bogoliubuv (GB) inequality with Percus Yevick hard sphere reference system have been reported in the present investigation. To describe electron-ion interaction we have used our newly constructed parameter free model potential along with Sarkar et al. local field correction function. Lastly, we conclude that our newly constructed model potential is capable to explain the thermodynamical properties of liquid lanthanides.

  15. Precision measurement of the photon detection efficiency of silicon photomultipliers using two integrating spheres.

    PubMed

    Yang, Seul Ki; Lee, J; Kim, Sug-Whan; Lee, Hye-Young; Jeon, Jin-A; Park, I H; Yoon, Jae-Ryong; Baek, Yang-Sik

    2014-01-13

    We report a new and improved photon counting method for the precision PDE measurement of SiPM detectors, utilizing two integrating spheres connected serially and calibrated reference detectors. First, using a ray tracing simulation and irradiance measurement results with a reference photodiode, we investigated irradiance characteristics of the measurement instrument, and analyzed dominating systematic uncertainties in PDE measurement. Two SiPM detectors were then used for PDE measurements between wavelengths of 368 and 850 nm and for bias voltages varying from around 70V. The resulting PDEs of the SiPMs show good agreement with those from other studies, yet with an improved accuracy of 1.57% (1σ). This was achieved by the simultaneous measurement with the NIST calibrated reference detectors, which suppressed the time dependent variation of source light. The technical details of the instrumentation, measurement results and uncertainty analysis are reported together with their implications.

  16. Density Measurement of Tridecane by using Hydrostatic Weighing System at Density Laboratory, NML-SIRIM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nor, Mohd. Fazrul Hisyam Mohd.; Othman, Hafidzah; Abidin, Abd. Rashid Zainal

    2009-07-07

    This paper presents the density measurement of tridecane by using hydrostatic weighing system, which is currently practised in Density Laboratory of National Metrology Laboratory (NML), SIRIM Berhad. This system weighed the crystal sphere while the crystal sphere was immersed in the tridecane. The volume and mass in air of the crystal sphere were calibrated at KRISS, Korea. The uncertainties of volume and mass in air of the crystal sphere were 4 ppm and 0.3 ppm respectively.

  17. Compact autonomous navigation system (CANS)

    NASA Astrophysics Data System (ADS)

    Hao, Y. C.; Ying, L.; Xiong, K.; Cheng, H. Y.; Qiao, G. D.

    2017-11-01

    Autonomous navigation of Satellite and constellation has series of benefits, such as to reduce operation cost and ground station workload, to avoid the event of crises of war and natural disaster, to increase spacecraft autonomy, and so on. Autonomous navigation satellite is independent of ground station support. Many systems are developed for autonomous navigation of satellite in the past 20 years. Along them American MANS (Microcosm Autonomous Navigation System) [1] of Microcosm Inc. and ERADS [2] [3] (Earth Reference Attitude Determination System) of Honeywell Inc. are well known. The systems anticipate a series of good features of autonomous navigation and aim low cost, integrated structure, low power consumption and compact layout. The ERADS is an integrated small 3-axis attitude sensor system with low cost and small volume. It has the Earth center measurement accuracy higher than the common IR sensor because the detected ultraviolet radiation zone of the atmosphere has a brightness gradient larger than that of the IR zone. But the ERADS is still a complex system because it has to eliminate many problems such as making of the sapphire sphere lens, birefringence effect of sapphire, high precision image transfer optical fiber flattener, ultraviolet intensifier noise, and so on. The marginal sphere FOV of the sphere lens of the ERADS is used to star imaging that may be bring some disadvantages., i.e. , the image energy and attitude measurements accuracy may be reduced due to the tilt image acceptance end of the fiber flattener in the FOV. Besides Japan, Germany and Russia developed visible earth sensor for GEO [4] [5]. Do we have a way to develop a cheaper/easier and more accurate autonomous navigation system that can be used to all LEO spacecraft, especially, to LEO small and micro satellites? To return this problem we provide a new type of the system—CANS (Compact Autonomous Navigation System) [6].

  18. Image method for induced surface charge from many-body system of dielectric spheres

    NASA Astrophysics Data System (ADS)

    Qin, Jian; de Pablo, Juan J.; Freed, Karl F.

    2016-09-01

    Charged dielectric spheres embedded in a dielectric medium provide the simplest model for many-body systems of polarizable ions and charged colloidal particles. We provide a multiple scattering formulation for the total electrostatic energy for such systems and demonstrate that the polarization energy can be rapidly evaluated by an image method that generalizes the image methods for conducting spheres. Individual contributions to the total electrostatic energy are ordered according to the number of polarized surfaces involved, and each additional surface polarization reduces the energy by a factor of (a/R)3ɛ, where a is the sphere radius, R the average inter-sphere separation, and ɛ the relevant dielectric mismatch at the interface. Explicit expressions are provided for both the energy and the forces acting on individual spheres, which can be readily implemented in Monte Carlo and molecular dynamics simulations of polarizable charged spheres, thereby avoiding costly computational techniques that introduce a surface charge distribution that requires numerical solution.

  19. IImage method for induced surface charge from many-body system of dielectric spheres

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Qin, Jian; de Pablo, Juan J.; Freed, Karl F.

    2016-09-28

    Charged dielectric spheres embedded in a dielectric medium provide the simplest model for many-body systems of polarizable ions and charged colloidal particles. We provide a multiple scattering formulation for the total electrostatic energy for such systems and demonstrate that the polarization energy can be rapidly evaluated by an image method that generalizes the image methods for conducting spheres. Individual contributions to the total electrostatic energy are ordered according to the number of polarized surfaces involved, and each additional surface polarization reduces the energy by a factor of (a/R)(3) epsilon, where a is the sphere radius, R the average inter-sphere separation,more » and. the relevant dielectric mismatch at the interface. Explicit expressions are provided for both the energy and the forces acting on individual spheres, which can be readily implemented in Monte Carlo and molecular dynamics simulations of polarizable charged spheres, thereby avoiding costly computational techniques that introduce a surface charge distribution that requires numerical solution.« less

  20. Steady Shear Viscosities of Two Hard Sphere Colloidal Dispersions

    NASA Astrophysics Data System (ADS)

    Cheng, Zhengdong; Chaikin, Paul M.; Phan, See-Eng; Russel, William B.; Zhu, Jixiang

    1996-03-01

    Though hard spheres have the simplest inter-particle potential, the many body hydrodynamic interactions are complex and the rheological properties of dispersions are not fully understood in the concentrated regime. We studied two model systems: colloidal poly-(Methyl Methacrylate) spheres with a grafted layer of poly-(12-hydroxy stearic acid) (PMMA/PHSA) and spherical Silica particles (PST-5, Nissan Chemical Industries, Ltd, Tokyo, Japan). Steady shear viscosities were measured by a Zimm viscometer. The high shear relative viscosity of the dispersions compares well with other hard sphere systems, but the low shear relative viscosity of PMMA/PHSA dispersions is η / η 0 = 50 at φ = 0.5 , higher than η / η 0 = 22 for other hard sphere systems, consistent with recently published data (Phys. Rev. Lett. 75(1995)958). Bare Silica spheres are used to clarify the effect of the grafted layer. With the silica spheres, volume fraction can be determined independent of intrinsic viscosity measurements; also, higher concentrated dispersions can be made.

  1. A new method to measure circular runout of end-milling spindle based on cutting mark

    NASA Astrophysics Data System (ADS)

    Zhou, Jianlai; Liu, Shuchun

    2008-12-01

    A practical method is introduced to measure the circular runout of a end-milling spindle system at high speed rotations without the need of a reference sphere. A workpiece is held on a linear slide which moves along the axial direction of the spindle. The spindle is then programmed to run at a specific speed. A very sharp edge cutter must be used and the depth of cut will be very shallow in order to keep the cutting force very small. The workpiece is then fed into the end mill in order to make a cutting mark of teens μm in depth. The cutting marks are circular, and their diameters are related to the circular runout of the spindle system. The cutting mark that is generated at a specific speed is expected to contain information about the spindle circular runout at this speed. In practice the cutting marks are not perfectly circular. Therefore, a best-fit circle of a cutting mark is needed to determine its diameter. A high-resolution edge detector machine is used for this purpose. Quantitative precision analysis was carried out to confirm the accuracy and repeatability of this new measurement technique. It is demonstrated that this technique for the measurement of spindle circular runout is an effective tool in verifying the actual running accuracy of spindles at their actual operating speeds and can be accomplished without the need for a reference sphere.

  2. Effect of fluid inertia on the motion of a collinear swimmer.

    PubMed

    Felderhof, B U

    2016-12-01

    The swimming of a two-sphere system and of a three-sphere chain in an incompressible viscous fluid is studied on the basis of simplified equations of motion which take account of both Stokes friction and added mass effects. The analysis is based on an explicit expression for the asymptotic periodic swimming velocity and a corresponding evaluation of the mean rate of dissipation. The mean swimming velocity of the two-sphere system is found to be nonvanishing provided that the two spheres are not identical. The swimming of a comparable chain of three identical spheres is much more efficient.

  3. Public sphere as assemblage: the cultural politics of roadside memorialization.

    PubMed

    Campbell, Elaine

    2013-09-01

    This paper investigates contemporary academic accounts of the public sphere. In particular, it takes stock of post-Habermasian public sphere scholarship, and acknowledges a lively and variegated debate concerning the multiple ways in which individuals engage in contemporary political affairs. A critical eye is cast over a range of key insights which have come to establish the parameters of what 'counts' as a/the public sphere, who can be involved, and where and how communicative networks are established. This opens up the conceptual space for re-imagining a/the public sphere as an assemblage. Making use of recent developments in Deleuzian-inspired assemblage theory - most especially drawn from DeLanda's (2006) 'new philosophy of society' - the paper sets out an alternative perspective on the notion of the public sphere, and regards it as a space of connectivity brought into being through a contingent and heterogeneous assemblage of discursive, visual and performative practices. This is mapped out with reference to the cultural politics of roadside memorialization. However, a/the public sphere as an assemblage is not simply a 'social construction' brought into being through a logic of connectivity, but is an emergent and ephemeral space which reflexively nurtures and assembles the cultural politics (and political cultures) of which it is an integral part. The discussion concludes, then, with a consideration of the contribution of assemblage theory to public sphere studies. (Also see Campbell 2009a). © London School of Economics and Political Science 2013.

  4. Ecological Systems Theory: Using Spheres of Influence to Support Small-unit Climate and Training

    DTIC Science & Technology

    2016-03-01

    identifying the model’s elements and influential individuals, define spheres of influence and construct a model that details the ecological systems...Research Report 1997 Ecological Systems Theory: Using Spheres of Influence to Support Small-unit Climate and Training...Technical review by: Sena Garven, U.S. Army Research Institute Michael D. Wood , Walter Reed Army Institute of Research

  5. Thermodynamic stability in elastic systems: Hard spheres embedded in a finite spherical elastic solid.

    PubMed

    Solano-Altamirano, J M; Goldman, Saul

    2015-12-01

    We determined the total system elastic Helmholtz free energy, under the constraints of constant temperature and volume, for systems comprised of one or more perfectly bonded hard spherical inclusions (i.e. "hard spheres") embedded in a finite spherical elastic solid. Dirichlet boundary conditions were applied both at the surface(s) of the hard spheres, and at the outer surface of the elastic solid. The boundary conditions at the surface of the spheres were used to describe the rigid displacements of the spheres, relative to their initial location(s) in the unstressed initial state. These displacements, together with the initial positions, provided the final shape of the strained elastic solid. The boundary conditions at the outer surface of the elastic medium were used to ensure constancy of the system volume. We determined the strain and stress tensors numerically, using a method that combines the Neuber-Papkovich spherical harmonic decomposition, the Schwartz alternating method, and Least-squares for determining the spherical harmonic expansion coefficients. The total system elastic Helmholtz free energy was determined by numerically integrating the elastic Helmholtz free energy density over the volume of the elastic solid, either by a quadrature, or a Monte Carlo method, or both. Depending on the initial position of the hard sphere(s) (or equivalently, the shape of the un-deformed stress-free elastic solid), and the displacements, either stationary or non-stationary Helmholtz free energy minima were found. The non-stationary minima, which involved the hard spheres nearly in contact with one another, corresponded to lower Helmholtz free energies, than did the stationary minima, for which the hard spheres were further away from one another.

  6. Vertical interferometer workstation for testing large spherical optics

    NASA Astrophysics Data System (ADS)

    Truax, B.

    2013-09-01

    The design of an interferometer workstation for the testing of large concave and convex spherical optics is presented. The workstation handles optical components and mounts up to 425 mm in diameter with mass of up to 40 kg with 6 axes of adjustment. A unique method for the implementation of focus, roll and pitch was used allowing for extremely precise adjustment. The completed system includes transmission spheres with f-numbers from f/1.6 to f/0.82 incorporating reference surface diameters of up to 306 mm and surface accuracies of better than 63 nm PVr. The design challenges and resulting solutions are discussed. System performance results are presented.

  7. Giant slip lengths of a simple fluid at vibrating solid interfaces

    NASA Astrophysics Data System (ADS)

    Drezet, Aurélien; Siria, Alessandro; Huant, Serge; Chevrier, Joël

    2010-04-01

    It has been shown recently [A. Siria, A. Drezet, F. Marchi, F. Comin, S. Huant, and J. Chevrier, Phys. Rev. Lett. 102, 254503 (2009)] that in the plane-plane configuration, a mechanical resonator vibrating close to a rigid wall in a simple fluid can be overdamped to a frozen regime. Here, by solving analytically the Navier-Stokes equations with partial slip boundary conditions at the solid-fluid interface, we develop a theoretical approach justifying and extending these earlier findings. We show in particular that in the perfect-slip regime, the abovementioned results are, in the plane-plane configuration, very general and robust with respect to lever geometry considerations. We compare the results to those obtained previously for the sphere moving perpendicularly and close to a plane in a simple fluid and discuss in more details the differences concerning the dependence of the friction forces with the gap distance separating the moving object (i.e., plane or sphere) from the fixed plane. We show that the plane-plane geometry is more sensitive than the sphere-plane geometry for the measurement of slippage coefficients. Finally, we show that the submicron fluidic effect reported in the reference above, and discussed further in the present work, can have dramatic implications in the design of nanoelectromechanical systems.

  8. Giant slip lengths of a simple fluid at vibrating solid interfaces.

    PubMed

    Drezet, Aurélien; Siria, Alessandro; Huant, Serge; Chevrier, Joël

    2010-04-01

    It has been shown recently [A. Siria, A. Drezet, F. Marchi, F. Comin, S. Huant, and J. Chevrier, Phys. Rev. Lett. 102, 254503 (2009)] that in the plane-plane configuration, a mechanical resonator vibrating close to a rigid wall in a simple fluid can be overdamped to a frozen regime. Here, by solving analytically the Navier-Stokes equations with partial slip boundary conditions at the solid-fluid interface, we develop a theoretical approach justifying and extending these earlier findings. We show in particular that in the perfect-slip regime, the abovementioned results are, in the plane-plane configuration, very general and robust with respect to lever geometry considerations. We compare the results to those obtained previously for the sphere moving perpendicularly and close to a plane in a simple fluid and discuss in more details the differences concerning the dependence of the friction forces with the gap distance separating the moving object (i.e., plane or sphere) from the fixed plane. We show that the plane-plane geometry is more sensitive than the sphere-plane geometry for the measurement of slippage coefficients. Finally, we show that the submicron fluidic effect reported in the reference above, and discussed further in the present work, can have dramatic implications in the design of nanoelectromechanical systems.

  9. The orbital mechanics of flight mechanics

    NASA Technical Reports Server (NTRS)

    Dunning, R. S.

    1973-01-01

    A reference handbook on modern dynamic orbit theory is presented. Starting from the most basic inverse-square law, the law of gravity for a sphere is developed, and the motion of point masses under the influence of a sphere is considered. The reentry theory and the orbital theory are discussed along with the relative motion between two bodies in orbit about the same planet. Relative-motion equations, rectangular coordinates, and the mechanics of simple rigid bodies under the influence of a gravity gradient field are also discussed.

  10. Implementation and simulations of the sphere solution in FAST

    NASA Astrophysics Data System (ADS)

    Murgolo, F. P.; Schirone, M. G.; Lattanzi, M.; Bernacca, P. L.

    1989-06-01

    The details of the implementation of the sphere solution software in the Fundamental Astronomy by Space Techniques (FAST) consortium, are described. The simulation results for realistic data sets, both with and without grid-step errors are given. Expected errors on the astrometric parameters of the primary stars and the precision of the reference great circle zero points, are provided as a function of mission duration. The design matrix, the diagrams of the context processor and the processors experimental results are given.

  11. Dependence on sphere size of the phase behavior of mixtures of rods and spheres

    NASA Astrophysics Data System (ADS)

    Urakami, Naohito; Imai, Masayuki

    2003-07-01

    By the addition of chondroitin sulfate (Chs) to the aqueous suspension of tobacco mosaic virus (TMV), the aggregation of TMV occurs at very dilute TMV concentration compared with the addition of polyethylene oxide (PEO). The difference of physical behavior between Chs and PEO is the chain conformation in solution. The Chs chain has a semirigid nature, whereas the PEO chain has a flexible nature. In this study, the Chs and PEO chains are simplified to spherical particles having different size, and we use the spherocylinder model for TMV particle. The effect of the sphere size on the phase behaviors in the mixtures of rods and spheres is investigated by Monte Carlo simulations. By the addition of small spheres, the system transforms from the miscible isotropic phase to the miscible nematic phase. On the other hand, by the addition of large spheres, the system changes from the miscible isotropic phase to the immiscible nematic phase through the immiscible isotropic phase. The different phase behaviors between the small and the large spheres originate from the difference of overlapping volume of the depletion zone. In addition, we perform the Monte Carlo simulations in the case that semirigid chains are used as the Chs chain models. The same phase behaviors are observed as the mixtures of rods and large spheres. Thus the sphere model captures the phase behaviors of rod and polymer mixture systems.

  12. INTERNATIONAL COMPARISON EXERCISE ON NEUTRON SPECTRA UNFOLDING IN BONNER SPHERES SPECTROMETRY: PROBLEM DESCRIPTION AND PRELIMINARY ANALYSIS.

    PubMed

    Gómez-Ros, J M; Bedogni, R; Domingo, C; Eakins, J S; Roberts, N; Tanner, R J

    2018-01-29

    This article describes the purpose, the proposed problems and the reference solutions of an international comparison on neutron spectra unfolding in Bonner spheres spectrometry, organised within the activities of EURADOS working group 6: computational dosimetry. The exercise considered four realistic situations: a medical accelerator, a workplace field, an irradiation room and a skyshine scenario. Although a detailed analysis of the submitted solutions is under preparation, the preliminary discussion of some physical aspects of the problem, e.g. the changes in the unfolding results due to the perturbation of the neutron field by the Bonner spheres, is presented. © The Author(s) 2018. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  13. Scientific and educational recommender systems

    NASA Astrophysics Data System (ADS)

    Guseva, A. I.; Kireev, V. S.; Bochkarev, P. V.; Kuznetsov, I. A.; Philippov, S. A.

    2017-01-01

    This article discusses the questions associated with the use of reference systems in the preparation of graduates in physical function. The objective of this research is creation of model of recommender system user from the sphere of science and education. The detailed review of current scientific and social network for scientists and the problem of constructing recommender systems in this area. The result of this study is to research user information model systems. The model is presented in two versions: the full one - in the form of a semantic network, and short - in a relational form. The relational model is the projection in the form of semantic network, taking into account the restrictions on the amount of bonds that characterize the number of information items (research results), which interact with the system user.

  14. Development and Performance of a Filter Radiometer Monitor System for Integrating Sphere Sources

    NASA Technical Reports Server (NTRS)

    Ding, Leibo; Kowalewski, Matthew G.; Cooper, John W.; Smith, GIlbert R.; Barnes, Robert A.; Waluschka, Eugene; Butler, James J.

    2011-01-01

    The NASA Goddard Space Flight Center (GSFC) Radiometric Calibration Laboratory (RCL) maintains several large integrating sphere sources covering the visible to the shortwave infrared wavelength range. Two critical, functional requirements of an integrating sphere source are short and long-term operational stability and repeatability. Monitoring the source is essential in determining the origin of systemic errors, thus increasing confidence in source performance and quantifying repeatability. If monitor data falls outside the established parameters, this could be an indication that the source requires maintenance or re-calibration against the National Institute of Science and Technology (NIST) irradiance standard. The GSFC RCL has developed a Filter Radiometer Monitoring System (FRMS) to continuously monitor the performance of its integrating sphere calibration sources in the 400 to 2400nm region. Sphere output change mechanisms include lamp aging, coating (e.g. BaSO4) deterioration, and ambient water vapor level. The Filter Radiometer Monitor System (FRMS) wavelength bands are selected to quantify changes caused by these mechanisms. The FRMS design and operation are presented, as well as data from monitoring four of the RCL s integrating sphere sources.

  15. On the mechanical stability of the body-centered cubic phase and the emergence of a metastable cI16 phase in classical hard sphere solids

    NASA Astrophysics Data System (ADS)

    Warshavsky, Vadim B.; Ford, David M.; Monson, Peter A.

    2018-01-01

    The stability of the body-centered cubic (bcc) solid phase of classical hard spheres is of intrinsic interest and is also relevant to the development of perturbation theories for bcc solids of other model systems. Using canonical ensemble Monte Carlo, we simulated systems initialized in a perfect bcc lattice at various densities in the solid region. We observed that the systems rapidly evolved into one of four structures that then persisted for the duration of the simulation. Remarkably, one of these structures was identified as cI16, a cubic crystalline structure with 16 particles in the unit cell, which has recently been observed experimentally in lithium and sodium solids at high pressures. The other three structures do not exhibit crystalline order but are characterized by common patterns in the radial distribution function and bond-orientational order parameter distribution; we refer to them as bcc-di, with i ranging from 1 to 3. We found similar outcomes when employing any of the three single occupancy cell (SOC) restrictions commonly used in the literature. We also ran long constant-pressure simulations with box shape fluctuations initiated from bcc and cI16 initial configurations. At lower pressures, all the systems evolved to defective face-centered cubic (fcc) or hexagonal close-packed (hcp) structures. At higher pressures, most of the systems initiated as bcc evolved to cI16 with some evolving to defective fcc/hcp. High pressure systems initiated from cI16 remained in that structure. We computed the chemical potential of cI16 using the Einstein crystal reference method and found that it is higher than that of fcc by ˜0.5kT-2.5kT over the pressure range studied, with the difference increasing with pressure. We find that the undistorted bcc solid, even with constant-volume and SOC restrictions applied, is so mechanically unstable that it is unsuitable for consideration as a metastable phase or as a reference system for studying bcc phases of other systems. On the other hand, cI16 is a mechanically stable structure that can spontaneously emerge from a bcc starting point but it is thermodynamically metastable relative to fcc or hcp.

  16. Application of identifying transmission spheres for spherical surface testing

    NASA Astrophysics Data System (ADS)

    Han, Christopher B.; Ye, Xin; Li, Xueyuan; Wang, Quanzhao; Tang, Shouhong; Han, Sen

    2017-06-01

    We developed a new application on Microsoft Foundation Classes (MFC) to identify correct transmission spheres (TS) for Spherical Surface Testing (SST). Spherical surfaces are important optical surfaces, and the wide application and high production rate of spherical surfaces necessitates an accurate and highly reliable measuring device. A Fizeau Interferometer is an appropriate tool for SST due to its subnanometer accuracy. It measures the contour of a spherical surface using a common path, which is insensitive to the surrounding circumstances. The Fizeau Interferometer transmits a wide laser beam, creating interference fringes from re-converging light from the transmission sphere and the test surface. To make a successful measurement, the application calculates and determines the appropriate transmission sphere for the test surface. There are 3 main inputs from the test surfaces that are utilized to determine the optimal sizes and F-numbers of the transmission spheres: (1) the curvatures (concave or convex), (2) the Radii of Curvature (ROC), and (3) the aperture sizes. The application will firstly calculate the F-numbers (i.e. ROC divided by aperture) of the test surface, secondly determine the correct aperture size of a convex surface, thirdly verify that the ROC of the test surface must be shorter than the reference surface's ROC of the transmission sphere, and lastly calculate the percentage of area that the test surface will be measured. However, the amount of interferometers and transmission spheres should be optimized when measuring large spherical surfaces to avoid requiring a large amount of interferometers and transmission spheres for each test surface. Current measuring practices involve tedious and potentially inaccurate calculations. This smart application eliminates human calculation errors, optimizes the selection of transmission spheres (including the least number required) and interferometer sizes, and increases efficiency.

  17. The vanishing limit of the square-well fluid: The adhesive hard-sphere model as a reference system

    NASA Astrophysics Data System (ADS)

    Largo, J.; Miller, M. A.; Sciortino, F.

    2008-04-01

    We report a simulation study of the gas-liquid critical point for the square-well potential, for values of well width δ as small as 0.005 times the particle diameter σ. For small δ, the reduced second virial coefficient at the critical point B2*c is found to depend linearly on δ. The observed weak linear dependence is not sufficient to produce any significant observable effect if the critical temperature Tc is estimated via a constant B2*c assumption, due to the highly nonlinear transformation between B2*c and Tc. This explains the previously observed validity of the law of corresponding states. The critical density ρc is also found to be constant when measured in units of the cube of the average distance between two bonded particles (1+0.5δ)σ. The possibility of describing the δ →0 dependence with precise functional forms provides improved accurate estimates of the critical parameters of the adhesive hard-sphere model.

  18. The vanishing limit of the square-well fluid: the adhesive hard-sphere model as a reference system.

    PubMed

    Largo, J; Miller, M A; Sciortino, F

    2008-04-07

    We report a simulation study of the gas-liquid critical point for the square-well potential, for values of well width delta as small as 0.005 times the particle diameter sigma. For small delta, the reduced second virial coefficient at the critical point B2*c is found to depend linearly on delta. The observed weak linear dependence is not sufficient to produce any significant observable effect if the critical temperature Tc is estimated via a constant B2*c assumption, due to the highly nonlinear transformation between B2*c and Tc. This explains the previously observed validity of the law of corresponding states. The critical density rho c is also found to be constant when measured in units of the cube of the average distance between two bonded particles (1+0.5 delta)sigma. The possibility of describing the delta-->0 dependence with precise functional forms provides improved accurate estimates of the critical parameters of the adhesive hard-sphere model.

  19. Roto-orbital dynamics of a triaxial rigid body around a sphere. Relative equilibria and stability

    NASA Astrophysics Data System (ADS)

    Crespo, F.; Ferrer, S.

    2018-06-01

    We study the roto-orbital motion of a triaxial rigid body around a sphere, which is assumed to be much more massive than the triaxial body. The associated dynamics of this system, which consists of a normalized Hamiltonian with respect to the fast angles (partial averaging), is investigated making use of variables referred to the total angular momentum. The first order approximation of this model is integrable. We carry out the analysis of the relative equilibria, which hinges principally in the dihedral angle between the orbital and rotational planes and the ratio among the moments of inertia ρ = (B - A) / (2 C - B - A) . In particular, the dynamics of the body frame, though formally given by the classical Euler equations, experiences changes of stability in the principal directions related to the roto-orbital coupling. When ρ = 1 / 3 , we find a family of relative equilibria connected to the unstable equilibria of the free rigid body.

  20. Emergent structures in reaction-advection-diffusion systems on a sphere.

    PubMed

    Krause, Andrew L; Burton, Abigail M; Fadai, Nabil T; Van Gorder, Robert A

    2018-04-01

    We demonstrate unusual effects due to the addition of advection into a two-species reaction-diffusion system on the sphere. We find that advection introduces emergent behavior due to an interplay of the traditional Turing patterning mechanisms with the compact geometry of the sphere. Unidirectional advection within the Turing space of the reaction-diffusion system causes patterns to be generated at one point of the sphere, and transported to the antipodal point where they are destroyed. We illustrate these effects numerically and deduce conditions for Turing instabilities on local projections to understand the mechanisms behind these behaviors. We compare this behavior to planar advection which is shown to only transport patterns across the domain. Analogous transport results seem to hold for the sphere under azimuthal transport or away from the antipodal points in unidirectional flow regimes.

  1. Emergent structures in reaction-advection-diffusion systems on a sphere

    NASA Astrophysics Data System (ADS)

    Krause, Andrew L.; Burton, Abigail M.; Fadai, Nabil T.; Van Gorder, Robert A.

    2018-04-01

    We demonstrate unusual effects due to the addition of advection into a two-species reaction-diffusion system on the sphere. We find that advection introduces emergent behavior due to an interplay of the traditional Turing patterning mechanisms with the compact geometry of the sphere. Unidirectional advection within the Turing space of the reaction-diffusion system causes patterns to be generated at one point of the sphere, and transported to the antipodal point where they are destroyed. We illustrate these effects numerically and deduce conditions for Turing instabilities on local projections to understand the mechanisms behind these behaviors. We compare this behavior to planar advection which is shown to only transport patterns across the domain. Analogous transport results seem to hold for the sphere under azimuthal transport or away from the antipodal points in unidirectional flow regimes.

  2. Monte Carlo simulation of Hamaker nanospheres coated with dipolar particles

    NASA Astrophysics Data System (ADS)

    Meyra, Ariel G.; Zarragoicoechea, Guillermo J.; Kuz, Victor A.

    2012-01-01

    Parallel tempering Monte Carlo simulation is carried out in systems of N attractive Hamaker spheres dressed with n dipolar particles, able to move on the surface of the spheres. Different cluster configurations emerge for given values of the control parameters. Energy per sphere, pair distribution functions of spheres and dipoles as function of temperature, density, external electric field, and/or the angular orientation of dipoles are used to analyse the state of aggregation of the system. As a consequence of the non-central interaction, the model predicts complex structures like self-assembly of spheres by a double crown of dipoles. This interesting result could be of help in understanding some recent experiments in colloidal science and biology.

  3. Structure of highly asymmetric hard-sphere mixtures: an efficient closure of the Ornstein-Zernike equations.

    PubMed

    Amokrane, S; Ayadim, A; Malherbe, J G

    2005-11-01

    A simple modification of the reference hypernetted chain (RHNC) closure of the multicomponent Ornstein-Zernike equations with bridge functions taken from Rosenfeld's hard-sphere bridge functional is proposed. Its main effect is to remedy the major limitation of the RHNC closure in the case of highly asymmetric mixtures--the wide domain of packing fractions in which it has no solution. The modified closure is also much faster, while being of similar complexity. This is achieved with a limited loss of accuracy, mainly for the contact value of the big sphere correlation functions. Comparison with simulation shows that inside the RHNC no-solution domain, it provides a good description of the structure, while being clearly superior to all the other closures used so far to study highly asymmetric mixtures. The generic nature of this closure and its good accuracy combined with a reduced no-solution domain open up the possibility to study the phase diagram of complex fluids beyond the hard-sphere model.

  4. Spectral correction factors for conventional neutron dosemeters used in high-energy neutron environments.

    PubMed

    Lee, K W; Sheu, R J

    2015-04-01

    High-energy neutrons (>10 MeV) contribute substantially to the dose fraction but result in only a small or negligible response in most conventional moderated-type neutron detectors. Neutron dosemeters used for radiation protection purpose are commonly calibrated with (252)Cf neutron sources and are used in various workplace. A workplace-specific correction factor is suggested. In this study, the effect of the neutron spectrum on the accuracy of dose measurements was investigated. A set of neutron spectra representing various neutron environments was selected to study the dose responses of a series of Bonner spheres, including standard and extended-range spheres. By comparing (252)Cf-calibrated dose responses with reference values based on fluence-to-dose conversion coefficients, this paper presents recommendations for neutron field characterisation and appropriate correction factors for responses of conventional neutron dosemeters used in environments with high-energy neutrons. The correction depends on the estimated percentage of high-energy neutrons in the spectrum or the ratio between the measured responses of two Bonner spheres (the 4P6_8 extended-range sphere versus the 6″ standard sphere). © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  5. Language Contact.

    ERIC Educational Resources Information Center

    Nelde, Peter Hans

    1995-01-01

    Examines the phenomenon of language contact and recent trends in linguistic contact research, which focuses on language use, language users, and language spheres. Also discusses the role of linguistic and cultural conflicts in language contact situations. (13 references) (MDM)

  6. A Bonner Sphere Spectrometer based on a large 6LiI(Eu) scintillator: Calibration in reference monoenergetic fields

    NASA Astrophysics Data System (ADS)

    Bedogni, R.; Pola, A.; Costa, M.; Monti, V.; Thomas, D. J.

    2018-07-01

    A Bonner Sphere spectrometer employing a large, 11 mm diameter × 3 mm thickness, 6LiI(Eu) scintillator (LL-BSS), was assembled. The purpose was to produce a BSS similar in sensitivity to those based on 3He sensors, but using alternative sensors. With respect to the traditional BSS based on the 4 mm (diameter) × 4 mm (height) 6LiI(Eu), this new BSS is a factor of 3 more sensitive. LL-BSS response matrix, determined with MCNPX, was experimentally evaluated with monoenergetic reference neutron fields of 144 keV, 565 keV and 1.2 MeV available at NPL (Teddington, UK). The results of the experiment confirmed the correctness of the response matrix within an overall uncertainty lower than ±2%.

  7. Efficient Implementation of the Invariant Imbedding T-Matrix Method and the Separation of Variables Method Applied to Large Nonspherical Inhomogeneous Particles

    NASA Technical Reports Server (NTRS)

    Bi, Lei; Yang, Ping; Kattawar, George W.; Mishchenko, Michael I.

    2012-01-01

    Three terms, ''Waterman's T-matrix method'', ''extended boundary condition method (EBCM)'', and ''null field method'', have been interchangeable in the literature to indicate a method based on surface integral equations to calculate the T-matrix. Unlike the previous method, the invariant imbedding method (IIM) calculates the T-matrix by the use of a volume integral equation. In addition, the standard separation of variables method (SOV) can be applied to compute the T-matrix of a sphere centered at the origin of the coordinate system and having a maximal radius such that the sphere remains inscribed within a nonspherical particle. This study explores the feasibility of a numerical combination of the IIM and the SOV, hereafter referred to as the IIMþSOV method, for computing the single-scattering properties of nonspherical dielectric particles, which are, in general, inhomogeneous. The IIMþSOV method is shown to be capable of solving light-scattering problems for large nonspherical particles where the standard EBCM fails to converge. The IIMþSOV method is flexible and applicable to inhomogeneous particles and aggregated nonspherical particles (overlapped circumscribed spheres) representing a challenge to the standard superposition T-matrix method. The IIMþSOV computational program, developed in this study, is validated against EBCM simulated spheroid and cylinder cases with excellent numerical agreement (up to four decimal places). In addition, solutions for cylinders with large aspect ratios, inhomogeneous particles, and two-particle systems are compared with results from discrete dipole approximation (DDA) computations, and comparisons with the improved geometric-optics method (IGOM) are found to be quite encouraging.

  8. AIE-doped poly(ionic liquid) photonic spheres: a single sphere-based customizable sensing platform for the discrimination of multi-analytes† †Electronic supplementary information (ESI) available: Synthesis and characterization of the AIE luminogen, experimental details, response profiles and results of the multivariate analysis. See DOI: 10.1039/c7sc02409f Click here for additional data file.

    PubMed Central

    Zhang, Wanlin; Gao, Ning; Cui, Jiecheng; Wang, Chen; Wang, Shiqiang; Zhang, Guanxin; Dong, Xiaobiao

    2017-01-01

    By simultaneously exploiting the unique properties of ionic liquids and aggregation-induced emission (AIE) luminogens, as well as photonic structures, a novel customizable sensing system for multi-analytes was developed based on a single AIE-doped poly(ionic liquid) photonic sphere. It was found that due to the extraordinary multiple intermolecular interactions involved in the ionic liquid units, one single sphere could differentially interact with broader classes of analytes, thus generating response patterns with remarkable diversity. Moreover, the optical properties of both the AIE luminogen and photonic structure integrated in the poly(ionic liquid) sphere provide multidimensional signal channels for transducing the involved recognition process in a complementary manner and the acquisition of abundant and sufficient sensing information could be easily achieved on only one sphere sensor element. More importantly, the sensing performance of our poly(ionic liquid) photonic sphere is designable and customizable through a simple ion-exchange reaction and target-oriented multi-analyte sensing can be conveniently realized using a selective receptor species, such as counterions, showing great flexibility and extendibility. The power of our single sphere-based customizable sensing system was exemplified by the successful on-demand detection and discrimination of four multi-analyte challenge systems: all 20 natural amino acids, nine important phosphate derivatives, ten metal ions and three pairs of enantiomers. To further demonstrate the potential of our spheres for real-life application, 20 amino acids in human urine and their 26 unprecedented complex mixtures were also discriminated between by the single sphere-based array. PMID:28989662

  9. Syllabus for Weizmann Course: Earth System Science 101

    NASA Technical Reports Server (NTRS)

    Wiscombe, Warren J.

    2011-01-01

    This course aims for an understanding of Earth System Science and the interconnection of its various "spheres" (atmosphere, hydrosphere, etc.) by adopting the view that "the microcosm mirrors the macrocosm". We shall study a small set of microcosims, each residing primarily in one sphere, but substantially involving at least one other sphere, in order to illustrate the kinds of coupling that can occur and gain a greater appreciation of the complexity of even the smallest Earth System Science phenomenon.

  10. Science on a Sphere

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    Researchers at the National Oceanic and Atmospheric Administration developed Science on a Sphere to help explain Earth system science to people of all ages. Animated images, ranging from space to ocean temperatures and more, can be seen on this interactive sphere.

  11. Dynamical tachyons on fuzzy spheres

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Berenstein, David; Institute for Advanced Study, School of Natural Science, Princeton, New Jersey 08540; Trancanelli, Diego

    2011-05-15

    We study the spectrum of off-diagonal fluctuations between displaced fuzzy spheres in the Berenstein-Maldacena-Nastase plane wave matrix model. The displacement is along the plane of the fuzzy spheres. We find that when two fuzzy spheres intersect at angles, classical tachyons develop and that the spectrum of these modes can be computed analytically. These tachyons can be related to the familiar Nielsen-Olesen instabilities in Yang-Mills theory on a constant magnetic background. Many features of the problem become more apparent when we compare with maximally supersymmetric Yang-Mills theory on a sphere, of which this system is a truncation. We also set upmore » a simple oscillatory trajectory on the displacement between the fuzzy spheres and study the dynamics of the modes as they become tachyonic for part of the oscillations. We speculate on their role regarding the possible thermalization of the system.« less

  12. Electrohydrodynamic interaction of spherical particles under Quincke rotation.

    PubMed

    Das, Debasish; Saintillan, David

    2013-04-01

    Weakly conducting dielectric particles suspended in a dielectric liquid of higher conductivity can undergo a transition to spontaneous sustained rotation when placed in a sufficiently strong dc electric field. This phenomenon of Quincke rotation has interesting implications for the rheology of these suspensions, whose effective viscosity can be controlled and reduced by application of an external field. While previous models based on the rotation of isolated particles have provided accurate estimates for this viscosity reduction in dilute suspensions, discrepancies have been reported in more concentrated systems where particle-particle interactions are likely significant. Motivated by this observation, we extend the classic description of Quincke rotation based on the Taylor-Melcher leaky dielectric model to account for pair electrohydrodynamic interactions between two identical spheres using the method of reflections. A coupled system of evolution equations for the dipole moments and angular velocities of the spheres is derived that accounts for electric dipole-dipole interactions and hydrodynamic rotlet interactions up to order O(R(-5)), where R is the separation distance between the spheres. A linear stability analysis of this system shows that interactions modify the value of the critical electric field for the onset of Quincke rotation: both electric and hydrodynamic interactions can either stabilize or destabilize the system depending on the orientation of the spheres, but the leading effect of interactions on the onset of rotation is hydrodynamic. We also analyze the dynamics in the nonlinear regime by performing numerical simulations of the governing equations. In the case of a pair of spheres that are fixed in space, we find that particle rotations always synchronize in magnitude at long times, though the directions of rotation of the spheres need not be the same. The steady-state angular velocity magnitude depends on the configuration of the spheres and electric field strength and agrees very well with an asymptotic estimate derived for corotating spheres. In the case of freely-suspended spheres, dipolar interactions are observed to lead to a number of distinct behaviors depending on the initial relative configuration of the spheres and on any infinitesimal initial perturbation introduced in the system: in some cases the spheres slowly separate in space while steadily rotating, while in other cases they pair up and either corotate or counterrotate depending on their orientation relative to the field.

  13. Electrohydrodynamic interaction of spherical particles under Quincke rotation

    NASA Astrophysics Data System (ADS)

    Das, Debasish; Saintillan, David

    2013-04-01

    Weakly conducting dielectric particles suspended in a dielectric liquid of higher conductivity can undergo a transition to spontaneous sustained rotation when placed in a sufficiently strong dc electric field. This phenomenon of Quincke rotation has interesting implications for the rheology of these suspensions, whose effective viscosity can be controlled and reduced by application of an external field. While previous models based on the rotation of isolated particles have provided accurate estimates for this viscosity reduction in dilute suspensions, discrepancies have been reported in more concentrated systems where particle-particle interactions are likely significant. Motivated by this observation, we extend the classic description of Quincke rotation based on the Taylor-Melcher leaky dielectric model to account for pair electrohydrodynamic interactions between two identical spheres using the method of reflections. A coupled system of evolution equations for the dipole moments and angular velocities of the spheres is derived that accounts for electric dipole-dipole interactions and hydrodynamic rotlet interactions up to order O(R-5), where R is the separation distance between the spheres. A linear stability analysis of this system shows that interactions modify the value of the critical electric field for the onset of Quincke rotation: both electric and hydrodynamic interactions can either stabilize or destabilize the system depending on the orientation of the spheres, but the leading effect of interactions on the onset of rotation is hydrodynamic. We also analyze the dynamics in the nonlinear regime by performing numerical simulations of the governing equations. In the case of a pair of spheres that are fixed in space, we find that particle rotations always synchronize in magnitude at long times, though the directions of rotation of the spheres need not be the same. The steady-state angular velocity magnitude depends on the configuration of the spheres and electric field strength and agrees very well with an asymptotic estimate derived for corotating spheres. In the case of freely-suspended spheres, dipolar interactions are observed to lead to a number of distinct behaviors depending on the initial relative configuration of the spheres and on any infinitesimal initial perturbation introduced in the system: in some cases the spheres slowly separate in space while steadily rotating, while in other cases they pair up and either corotate or counterrotate depending on their orientation relative to the field.

  14. Corrected Four-Sphere Head Model for EEG Signals.

    PubMed

    Næss, Solveig; Chintaluri, Chaitanya; Ness, Torbjørn V; Dale, Anders M; Einevoll, Gaute T; Wójcik, Daniel K

    2017-01-01

    The EEG signal is generated by electrical brain cell activity, often described in terms of current dipoles. By applying EEG forward models we can compute the contribution from such dipoles to the electrical potential recorded by EEG electrodes. Forward models are key both for generating understanding and intuition about the neural origin of EEG signals as well as inverse modeling, i.e., the estimation of the underlying dipole sources from recorded EEG signals. Different models of varying complexity and biological detail are used in the field. One such analytical model is the four-sphere model which assumes a four-layered spherical head where the layers represent brain tissue, cerebrospinal fluid (CSF), skull, and scalp, respectively. While conceptually clear, the mathematical expression for the electric potentials in the four-sphere model is cumbersome, and we observed that the formulas presented in the literature contain errors. Here, we derive and present the correct analytical formulas with a detailed derivation. A useful application of the analytical four-sphere model is that it can serve as ground truth to test the accuracy of numerical schemes such as the Finite Element Method (FEM). We performed FEM simulations of the four-sphere head model and showed that they were consistent with the corrected analytical formulas. For future reference we provide scripts for computing EEG potentials with the four-sphere model, both by means of the correct analytical formulas and numerical FEM simulations.

  15. Corrected Four-Sphere Head Model for EEG Signals

    PubMed Central

    Næss, Solveig; Chintaluri, Chaitanya; Ness, Torbjørn V.; Dale, Anders M.; Einevoll, Gaute T.; Wójcik, Daniel K.

    2017-01-01

    The EEG signal is generated by electrical brain cell activity, often described in terms of current dipoles. By applying EEG forward models we can compute the contribution from such dipoles to the electrical potential recorded by EEG electrodes. Forward models are key both for generating understanding and intuition about the neural origin of EEG signals as well as inverse modeling, i.e., the estimation of the underlying dipole sources from recorded EEG signals. Different models of varying complexity and biological detail are used in the field. One such analytical model is the four-sphere model which assumes a four-layered spherical head where the layers represent brain tissue, cerebrospinal fluid (CSF), skull, and scalp, respectively. While conceptually clear, the mathematical expression for the electric potentials in the four-sphere model is cumbersome, and we observed that the formulas presented in the literature contain errors. Here, we derive and present the correct analytical formulas with a detailed derivation. A useful application of the analytical four-sphere model is that it can serve as ground truth to test the accuracy of numerical schemes such as the Finite Element Method (FEM). We performed FEM simulations of the four-sphere head model and showed that they were consistent with the corrected analytical formulas. For future reference we provide scripts for computing EEG potentials with the four-sphere model, both by means of the correct analytical formulas and numerical FEM simulations. PMID:29093671

  16. Optical characterization of tissue mimicking phantoms by a vertical double integrating sphere system

    NASA Astrophysics Data System (ADS)

    Han, Yilin; Jia, Qiumin; Shen, Shuwei; Liu, Guangli; Guo, Yuwei; Zhou, Ximing; Chu, Jiaru; Zhao, Gang; Dong, Erbao; Allen, David W.; Lemaillet, Paul; Xu, Ronald

    2016-03-01

    Accurate characterization of absorption and scattering properties for biologic tissue and tissue-simulating materials enables 3D printing of traceable tissue-simulating phantoms for medical spectral device calibration and standardized medical optical imaging. Conventional double integrating sphere systems have several limitations and are suboptimal for optical characterization of liquid and soft materials used in 3D printing. We propose a vertical double integrating sphere system and the associated reconstruction algorithms for optical characterization of phantom materials that simulate different human tissue components. The system characterizes absorption and scattering properties of liquid and solid phantom materials in an operating wavelength range from 400 nm to 1100 nm. Absorption and scattering properties of the phantoms are adjusted by adding titanium dioxide powder and India ink, respectively. Different material compositions are added in the phantoms and characterized by the vertical double integrating sphere system in order to simulate the human tissue properties. Our test results suggest that the vertical integrating sphere system is able to characterize optical properties of tissue-simulating phantoms without precipitation effect of the liquid samples or wrinkling effect of the soft phantoms during the optical measurement.

  17. Thermal Cycle Testing of the Powersphere Engineering Development Unit

    NASA Technical Reports Server (NTRS)

    Curtis, Henry; Piszczor, Mike; Kerslake, Thomas W.; Peterson, Todd T.; Scheiman, David A.; Simburger, Edward J.; Giants, Thomas W.; Matsumoto, James H.; Garcia, Alexander; Liu, Simon H.; hide

    2007-01-01

    During the past three years the team of The Aerospace Corporation, Lockheed Martin Space Systems, NASA Glenn Research Center, and ILC Dover LP have been developing a multifunctional inflatable structure for the PowerSphere concept under contract with NASA (NAS3-01115). The PowerSphere attitude insensitive solar power-generating microsatellite, which could be used for many different space and Earth science purposes, is ready for further refinement and flight demonstration. The development of micro- and nanosatellites requires the energy collection system, namely the solar array, to be of lightweight and small size. The limited surface area of these satellites precludes the possibility of body mounting the solar array system for required power generation. The use of large traditional solar arrays requires the support of large satellite volumes and weight and also requires a pointing apparatus. The current PowerSphere concept (geodetic sphere), which was envisioned in the late 1990 s by Mr. Simburger of The Aerospace Corporation, has been systematically developed in the past several years.1-7 The PowerSphere system is a low mass and low volume system suited for micro and nanosatellites. It is a lightweight solar array that is spherical in shape and does not require a pointing apparatus. The recently completed project culminated during the third year with the manufacturing of the PowerSphere Engineering Development Unit (EDU). One hemisphere of the EDU system was tested for packing and deployment and was subsequently rigidized. The other hemisphere was packed and stored for future testing in an uncured state. Both cured and uncured hemisphere components were delivered to NASA Glenn Research Center for thermal cycle testing and long-term storage respectively. This paper will discuss the design, thermal cycle testing of the PowerSphere EDU.

  18. Computation of the Quantities Describing the Lunar Librations in the Astronomical Almanac

    DTIC Science & Technology

    2010-08-01

    this system ~e ( COS( -(3) cost >. + 180’ - tt)) cost -(3) sine>. + 180’ - tt) sin(-(3) , (1) Consid~r neXt, point M referred to axes OX’’z’ iIi...now write (7) as the three equl\\tions " cos b cos(1 + LM - tt) = cosj3 cost >. - tt - N) cos b sin(1 + LM - tt) ,= cos Lcosj3si,n(>’,- tt -’N) ,- sin...8217?’~ on . .the sel~~~centric sphere. The geocentric right ascension and declination of the Moon are 0:, 0 and so the right ascension and declination of

  19. Energy absorbing system for mechanical impacts

    NASA Technical Reports Server (NTRS)

    Collins, E. R., Jr.

    1972-01-01

    System is described based on use of arrangement of crushable hollow spheres bonded together in layers of progressively different diameter, with largest diameter spheres positioned to receive impact forces initially. System is particularly useful for delivery of payloads by air-drop techniques.

  20. Development and validation of RAYDOSE: a Geant4-based application for molecular radiotherapy

    NASA Astrophysics Data System (ADS)

    Marcatili, S.; Pettinato, C.; Daniels, S.; Lewis, G.; Edwards, P.; Fanti, S.; Spezi, E.

    2013-04-01

    We developed and validated a Monte-Carlo-based application (RAYDOSE) to generate patient-specific 3D dose maps on the basis of pre-treatment imaging studies. A CT DICOM image is used to model patient geometry, while repeated PET scans are employed to assess radionuclide kinetics and distribution at the voxel level. In this work, we describe the structure of this application and present the tests performed to validate it against reference data and experiments. We used the spheres of a NEMA phantom to calculate S values and total doses. The comparison with reference data from OLINDA/EXM showed an agreement within 2% for a sphere size above 2.8 cm diameter. A custom heterogeneous phantom composed of several layers of Perspex and lung equivalent material was used to compare TLD measurements of gamma radiation from 131I to Monte Carlo simulations. An agreement within 5% was found. RAYDOSE has been validated against reference data and experimental measurements and can be a useful multi-modality platform for treatment planning and research in MRT.

  1. A modular, energy-based approach to the development of nickel containing molecular electrocatalysts for hydrogen production and oxidation.

    PubMed

    Shaw, Wendy J; Helm, Monte L; DuBois, Daniel L

    2013-01-01

    This review discusses the development of molecular electrocatalysts for H2 production and oxidation based on nickel. A modular approach is used in which the structure of the catalyst is divided into first, second, and outer coordination spheres. The first coordination sphere consists of the ligands bound directly to the metal center, and this coordination sphere can be used to control such factors as the presence or absence of vacant coordination sites, redox potentials, hydride donor abilities and other important thermodynamic parameters. The second coordination sphere includes functional groups such as pendent acids or bases that can interact with bound substrates such as H2 molecules and hydride ligands, but that do not form strong bonds with the metal center. These functional groups can play diverse roles such as assisting the heterolytic cleavage of H2, controlling intra- and intermolecular proton transfer reactions, and providing a physical pathway for coupling proton and electron transfer reactions. By controlling both the hydride donor ability of the catalysts using the first coordination sphere and the proton donor abilities of the functional groups in the second coordination sphere, catalysts can be designed that are biased toward H2 production, oxidation, or bidirectional (catalyzing both H2 oxidation and production). The outer coordination sphere is defined as that portion of the catalytic system that is beyond the second coordination sphere. This coordination sphere can assist in the delivery of protons and electrons to and from the catalytically active site, thereby adding another important avenue for controlling catalytic activity. Many features of these simple catalytic systems are good models for enzymes, and these simple systems provide insights into enzyme function and reactivity that may be difficult to probe in enzymes. This article is part of a Special Issue entitled: Metals in Bioenergetics and Biomimetics Systems. Copyright © 2013 Elsevier B.V. All rights reserved.

  2. Three-sphere low-Reynolds-number swimmer with a cargo container.

    PubMed

    Golestanian, R

    2008-01-01

    A recently introduced model for an autonomous swimmer at low Reynolds number that is comprised of three spheres connected by two arms is considered when one of the spheres has a large radius. The Stokes hydrodynamic flow associated with the swimming strokes and net motion of this system can be studied analytically using the Stokes Green's function of a point force in front of a sphere of arbitrary radius R provided by Oseen. The swimming velocity is calculated, and shown to scale as 1/R3 with the radius of the sphere.

  3. Workplace testing of the new single sphere neutron spectrometer based on Dysprosium activation foils (Dy-SSS)

    NASA Astrophysics Data System (ADS)

    Bedogni, R.; Gómez-Ros, J. M.; Esposito, A.; Gentile, A.; Chiti, M.; Palacios-Pérez, L.; Angelone, M.; Tana, L.

    2012-08-01

    A photon insensitive passive neutron spectrometer consisting of a single moderating polyethylene sphere with Dysprosium activation foils arranged along three perpendicular axes was designed by CIEMAT and INFN. The device is called Dy-SSS (Dy foil-based Single Sphere Spectrometer). It shows nearly isotropic response in terms of neutron fluence up to 20 MeV. The first prototype, previously calibrated with 14 MeV neutrons, has been recently tested in workplaces having different energy and directional distributions. These are a 2.5 MeV nearly mono-chromatic and mono-directional beam available at the ENEA Frascati Neutron Generator (FNG) and the photo-neutron field produced in a 15 MV Varian CLINAC DHX medical accelerator, located in the Ospedale S. Chiara (Pisa). Both neutron spectra are known through measurements with a Bonner Sphere Spectrometer. In both cases the experimental response of the Dy-SSS agrees with the reference data. Moreover, it is demonstrated that the spectrometric capability of the new device are independent from the directional distribution of the neutron field. This opens the way to a new generation of moderation-based neutron instruments, presenting all advantages of the Bonner sphere spectrometer without the disadvantage of the repeated exposures. This concept is being developed within the NESCOFI@BTF project of INFN (Commissione Scientifica Nazionale 5).

  4. A numerical approximation to the elastic properties of sphere-reinforced composites

    NASA Astrophysics Data System (ADS)

    Segurado, J.; Llorca, J.

    2002-10-01

    Three-dimensional cubic unit cells containing 30 non-overlapping identical spheres randomly distributed were generated using a new, modified random sequential adsortion algorithm suitable for particle volume fractions of up to 50%. The elastic constants of the ensemble of spheres embedded in a continuous and isotropic elastic matrix were computed through the finite element analysis of the three-dimensional periodic unit cells, whose size was chosen as a compromise between the minimum size required to obtain accurate results in the statistical sense and the maximum one imposed by the computational cost. Three types of materials were studied: rigid spheres and spherical voids in an elastic matrix and a typical composite made up of glass spheres in an epoxy resin. The moduli obtained for different unit cells showed very little scatter, and the average values obtained from the analysis of four unit cells could be considered very close to the "exact" solution to the problem, in agreement with the results of Drugan and Willis (J. Mech. Phys. Solids 44 (1996) 497) referring to the size of the representative volume element for elastic composites. They were used to assess the accuracy of three classical analytical models: the Mori-Tanaka mean-field analysis, the generalized self-consistent method, and Torquato's third-order approximation.

  5. Science on a Sphere exhibit

    NASA Image and Video Library

    2009-03-31

    Students from Xavier University Preparatory School in New Orleans view the newest exhibit at StenniSphere, the visitor center at NASA's John C. Stennis Space Center - Science on a Sphere, a 68-inch global presentation of planetary data. StenniSphere is only the third NASA visitor center to offer the computer system, which uses four projectors to display data on a globe and present a dynamic, revolving, animated view of Earth and other planets.

  6. Science on a Sphere exhibit

    NASA Technical Reports Server (NTRS)

    2009-01-01

    Students from Xavier University Preparatory School in New Orleans view the newest exhibit at StenniSphere, the visitor center at NASA's John C. Stennis Space Center - Science on a Sphere, a 68-inch global presentation of planetary data. StenniSphere is only the third NASA visitor center to offer the computer system, which uses four projectors to display data on a globe and present a dynamic, revolving, animated view of Earth and other planets.

  7. Enhancements to the timing of the OMEGA laser system to improve illumination uniformity

    NASA Astrophysics Data System (ADS)

    Donaldson, W. R.; Katz, J.; Kosc, T. Z.; Kelly, J. H.; Hill, E. M.; Bahr, R. E.

    2016-09-01

    Two diagnostics have been developed to improve the uniformity on the OMEGA Laser System, which is used for inertial confinement fusion (ICF) research. The first diagnostic measures the phase of an optical modulator (used for the spectral dispersion technique employed on OMEGA to enhance spatial smoothing), which adds bandwidth to the optical pulse. Setting this phase precisely is required to reduce pointing errors. The second diagnostic ensures that the arrival times of all the beams are synchronized. The arrival of each of the 60 OMEGA beams is measured by placing a 1-mm diffusing sphere at target chamber center. By comparing the arrival time of each beam with respect to a reference pulse, the measured timing spread of the OMEGA Laser System is now 3.8 ps.

  8. Spherical versus flat displays for communicating climate science concepts through stories

    NASA Astrophysics Data System (ADS)

    Schollaert Uz, S.; Storksdieck, M.; Duncan, B. N.

    2016-12-01

    One of the most compelling ways to display global Earth science data is through spherical displays. Museums around the world use Science On a Sphere for informal education of the general public, commonly for Earth science. An increasing number of universities and K-12 school systems are acquiring spheres to support formal education curriculum, but the use of spheres in education is relatively new and understanding of their advantages and best practices is still evolving. Many museums do not have the resources to staff their sphere with a facilitator or they have high turn-over of volunteer facilitators without a science background. Many K-12 teachers lack resources or training needed to utilize sphere technology to address global phenomena or Earth system science. One solution to this "facilitator-problem" has been the creation of "canned shows" for spheres, like ClimateBits. These are short videos that help people visualize Earth science concepts through global data sets and simple story-telling. To understand whether and when data driven story-telling works best on a sphere, we surveyed groups that saw identical Earth system science stories presented on a spherical display versus a flat screen. We also surveyed identical groups using live Earth science data story-telling compared to the ClimateBits videos. Some of the advantages of each format were most apparent in the qualitative comments at the end of the surveys

  9. Hydration entropy change from the hard sphere model.

    PubMed

    Graziano, Giuseppe; Lee, Byungkook

    2002-12-10

    The gas to liquid transfer entropy change for a pure non-polar liquid can be calculated quite accurately using a hard sphere model that obeys the Carnahan-Starling equation of state. The same procedure fails to produce a reasonable value for hydrogen bonding liquids such as water, methanol and ethanol. However, the size of the molecules increases when the hydrogen bonds are turned off to produce the hard sphere system and the volume packing density rises. We show here that the hard sphere system that has this increased packing density reproduces the experimental transfer entropy values rather well. The gas to water transfer entropy values for small non-polar hydrocarbons is also not reproduced by a hard sphere model, whether one uses the normal (2.8 A diameter) or the increased (3.2 A) size for water. At least part of the reason that the hard sphere model with 2.8 A size water produces too small entropy change is that the size of water is too small for a system without hydrogen bonds. The reason that the 3.2 A model also produces too small entropy values is that this is an overly crowded system and that the free volume introduced in the system by the addition of a solute molecule produces too much of a relief to this crowding. A hard sphere model, in which the free volume increase is limited by requiring that the average surface-to-surface distance between the solute and water molecules is the same as that between the increased-size water molecules, does approximately reproduce the experimental hydration entropy values. Copyright 2002 Elsevier Science B.V.

  10. The Precision Expandable Radar Calibration Sphere (PERCS) With Applications for Laser Imaging and Ranging

    NASA Astrophysics Data System (ADS)

    Bernhardt, P.; Nicholas, A.; Thomas, L.; Davis, M.; Hoberman, C.; Davis, M.

    The Naval Research Laboratory will provide an orbiting calibration sphere to be used with ground-based laser imaging telescopes and HF radio systems. The Precision Expandable Radar Calibration Sphere (PERCS) is a practical, reliable, high-performance HF calibration sphere and laser imaging target to orbit at about 600 km altitude. The sphere will be made of a spherical wire frame with aspect independent radar cross section in the 3 to 35 MHz frequency range. The necessary launch vehicle to place the PERCS in orbit will be provided by the Department of Defense Space Test Program. The expandable calibration target has a stowed diameter of 1 meter and a fully deployed diameter of 10.2 meters. A separate deployment mechanism is provided for the sphere. After deployment, the Precision Expandable Radar Calibration Sphere (PERCS) with 180 vertices will be in a high inclination orbit to scatter radio pulses from a number of ground systems, including (1) over-the-horizon (OTH) radars operated by the United States and Australia; (2) high power HF facilities such as HAARP in Alaska, EISCAT in Norway, and Arecibo in Puerto Rico; (3) the chain of high latitude SuperDARN radars used for auroral region mapping; and (4) HF direction finding for Navy ships. With the PERCS satellite, the accuracy of HF radars can be periodically checked for range, elevation, and azimuth errors. In addition, each of the 360 vertices on the PERCS sphere will support an optical retro-reflector for operations with ground laser facilities used to track satellites. The ground laser systems will be used to measure the precise location of the sphere within one cm accuracy and will provide the spatial orientation of the sphere as well as the rotation rate. The Department of Defense facilities that can use the corner-cube reflectors on the PERCS include (1) the Air Force Maui Optical Site (AMOS), (2) the Starfire Optical Range (SOR), and (3) the NRL Optical Test Facility (OTF).

  11. Hyperspectral Signatures (400 to 2500 nm) of Vegetation, Minerals, Soils, Rocks, and Cultural Features: Laboratory and Field Measurements

    DTIC Science & Technology

    1990-12-01

    nadir radiometer viewing angle. The reference standard was a 25.4 cm x 25.4 cm x 1.0 cm pressed Halon "Spectralon" plate that was backed by a 0.5 cm...against the sphere’s sample port. Light transmitted through the leaf was trapped in the sample chamber and did not pass back into the integrating sphere...leaf layers. The leaves were added to the back of the stack, so leaf #1 was always the first leaf in the stack. Each spectrum was taken in the lower 1

  12. Some Consequences of the Expansion of the Universe on Small Scales

    NASA Astrophysics Data System (ADS)

    Harutyunian, H. A.

    2017-12-01

    The possibility of detecting the accelerated expansion of the universe at all its points is examined. Observational data indicative of Hubble expansion on small scales are adduced for this purpose. The validity of current opinion on the equilibrium of systems of cosmic objects is also discussed. It is noted that this opinion is a simple consequence of the unproved Kant-Laplace hypothesis on the formation of cosmic objects and systems of them. It is proposed that a system attached to the cosmological horizon be used as a reference system. It is noted that all points on this sphere are an initial point from which expansion of the observed universe of the given observer began. The numerical value of the acceleration obtained in this way is almost the same as the anomalous acceleration found by space probes.

  13. Cavitation and radicals drive the sonochemical synthesis of functional polymer spheres

    DOE PAGES

    Narayanan, Badri; Deshmukh, Sanket A.; Shrestha, Lok Kumar; ...

    2016-07-25

    Sonochemical synthesis can lead to a dramatic increase in the kinetics of formation of polymer spheres (templates for carbon spheres) compared to the modified Stober silica method applied to produce analogous polymer spheres. Reactive molecular dynamics simulations of the sonochemical process indicate a significantly enhanced rate of polymer sphere formation starting from resorcinol and formaldehyde precursors. The associated chemical reaction kinetics enhancement due to sonication is postulated to arise from the localized lowering of atomic densities, localized heating, and generation of radicals due to cavitation collapse in aqueous systems. This dramatic increase in reaction rates translates into enhanced nucleation andmore » growth of the polymer spheres. Finally, the results are of broad significance to understanding mechanisms of sonication induced synthesis as well as technologies utilizing polymers spheres.« less

  14. Cavitation and radicals drive the sonochemical synthesis of functional polymer spheres

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Narayanan, Badri, E-mail: bnarayanan@anl.gov; Deshmukh, Sanket A.; Sankaranarayanan, Subramanian K. R. S., E-mail: ssankaranarayanan@anl.gov

    2016-07-25

    Sonochemical synthesis can lead to a dramatic increase in the kinetics of formation of polymer spheres (templates for carbon spheres) compared to the modified Stöber silica method applied to produce analogous polymer spheres. Reactive molecular dynamics simulations of the sonochemical process indicate a significantly enhanced rate of polymer sphere formation starting from resorcinol and formaldehyde precursors. The associated chemical reaction kinetics enhancement due to sonication is postulated to arise from the localized lowering of atomic densities, localized heating, and generation of radicals due to cavitation collapse in aqueous systems. This dramatic increase in reaction rates translates into enhanced nucleation andmore » growth of the polymer spheres. The results are of broad significance to understanding mechanisms of sonication induced synthesis as well as technologies utilizing polymers spheres.« less

  15. Self-renewal and multilineage differentiation of mouse dental epithelial stem cells.

    PubMed

    Chang, Julia Yu Fong; Wang, Cong; Jin, Chengliu; Yang, Chaofeng; Huang, Yanqing; Liu, Junchen; McKeehan, Wallace L; D'Souza, Rena N; Wang, Fen

    2013-11-01

    Understanding the cellular and molecular mechanisms underlying the self-renewal and differentiation of dental epithelial stem cells (DESCs) that support the unlimited growth potential of mouse incisors is critical for developing novel tooth regenerative therapies and unraveling the pathogenesis of odontogenic tumors. However, analysis of DESC properties and regulation has been limited by the lack of an in vitro assay system and well-documented DESC markers. Here, we describe an in vitro sphere culture system to isolate the DESCs from postnatal mouse incisor cervical loops (CLs) where the DESCs are thought to reside. The dissociated cells from CLs were able to expand and form spheres for multiple generations in the culture system. Lineage tracing indicated that DESC within the spheres were epithelial in origin as evident by lineage tracing. Upon stimulation, the sphere cells differentiated into cytokeratin 14- and amelogenin-expressing and mineral material-producing cells. Compared to the CL tissue, sphere cells expressed high levels of expression of Sca-1, CD49f (also designated as integrin α6), and CD44. Fluorescence-activated cell sorting (FACS) analyses of mouse incisor CL cells further showed that the CD49f(Bright) population was enriched in sphere-forming cells. In addition, the CD49f(Bright) population includes both slow-cycling and Lgr5(+) DESCs. The in vitro sphere culture system and identification of CD49f(Bright) as a DESC marker provide a novel platform for enriching DESCs, interrogating how maintenance, cell fate determination, and differentiation of DESCs are regulated, and developing tooth regenerative therapies. © 2013.

  16. Self-renewal and Multilineage Differentiation of Mouse Dental Epithelial Stem Cells

    PubMed Central

    Chang, Julia Yu Fong; Wang, Cong; Jin, Chengliu; Yang, Chaofeng; Huang, Yanqing; Liu, Junchen; McKeehan, Wallace L.; D’Souza, Rena N.; Wang, Fen

    2013-01-01

    Understanding the cellular and molecular mechanisms underlying the self-renewal and differentiation of dental epithelial stem cells (DESCs) that support the unlimited growth potential of mouse incisors is critical for developing novel tooth regenerative therapies and unraveling the pathogenesis of odontogenic tumors. However, analysis of DESC properties and regulation has been limited by the lack of an in vitro assay system and well-documented DESC markers. Here, we describe an in vitro sphere culture system to isolate the DESCs from postnatal mouse incisor cervical loops (CLs) where the DESCs are thought to reside. The dissociated cells from CLs were able to expand and form spheres for multiple generations in the culture system. Lineage tracing indicated that DESC within the spheres were epithelial in origin as evident by lineage tracing. Upon stimulation, the sphere cells differentiated into cytokeratin 14- and amelogenin-expressing and mineral material-producing cells. Compared to the CL tissue, sphere cells expressed high levels of expression of Sca-1, CD49f (also designated as integrin α6), and CD44. Fluorescence-activated cell sorting (FACS) analyses of mouse incisor CL cells further showed that the CD49fBright population was enriched in sphere-forming cells. In addition, the CD49fBright population includes both slow-cycling and Lgr5+ DESCs. The in vitro sphere culture system and identification of CD49fBright as a DESC marker provide a novel plateform for enriching DESCs, interrogating how maintenance, cell fate determination, and differentiation of DESCs are regulated, and developing tooth regenerative therapies. PMID:23906788

  17. Structure and thermodynamics of liquid alkali metals in variational modified hypernetted-chain theory

    NASA Astrophysics Data System (ADS)

    Chen, H. C.; Lai, S. K.

    1992-03-01

    The role of the Percus-Yevick hard-sphere bridge function in the modified hypernetted-chain integral equation is examined within the context of Lado's criterion [F. Lado, S. M. Foiles, and N. W. Ashcroft, Phys. Rev. A 28, 2374 (1983)]. It is found that the commonly used Lado's criterion, which takes advantage of the analytical simplicity of the Percus-Yevick hard-sphere bridge function, is inadequate for determining an accurate static pair-correlation function. Following Rosenfeld [Y. Rosenfeld, Phys. Rev. A 29, 2877 (1984)], we reconsider Lado's criterion in the so-called variational modified hypernetted-chain theory. The main idea is to construct a free-energy functional satisfying the virial-energy thermodynamic self-consistency. It turns out that the widely used Gibbs-Bogoliubov inequality is equivalent to this integral approach of Lado's criterion. Detailed comparison between the presently obtained structural and thermodynamic quantities for liquid alkali metals and those calculated also in the modified hypernetted-chain theory but with the one-component-plasma reference system leads us to a better understanding of the universality property of the bridge function.

  18. Optical and morphological study of disorder in opals

    NASA Astrophysics Data System (ADS)

    Palacios-Lidón, E.; Juárez, B. H.; Castillo-Martínez, E.; López, C.

    2005-03-01

    An optical and morphological study has been carried out to understand the role of intrinsic defects in the optical properties of opal-based photonic crystals. By doping poly(methylmethacrylate) (PMMA) thin-film opals with larger polystyrene (PS) spheres, structural disorder has being generated perturbing the PMMA matrix periodicity. It is shown that this disorder dramatically affects the optical response of the system worsening its photonic properties. It has been found that the effect of doping is highly dependent not only on the concentration but also on the relative size of the dopant with reference to the matrix. Through a detailed scanning electron microscopy inspection, the sort of structural defects involved, derived from the different particle size used, has been characterized. A direct relationship between the observed optical response with the different perturbations generated in the lattice has been found. In addition, from this study it can be concluded that it is possible to grow high quality alloyed photonic crystals, exhibiting intermediate photonic properties between pure PMMA and pure PS opals by simple sphere size matching and variation of the relative concentration of both components.

  19. Theory of an experiment in an orbiting space laboratory to determine the gravitational constant.

    NASA Technical Reports Server (NTRS)

    Vinti, J. P.

    1972-01-01

    An experiment is discussed for determining the gravitational constant with the aid of an isolated system consisting of an artificial satellite moving around an artificial planet. The experiment is to be conducted in a spherical laboratory traveling in an orbit around the earth. Difficulties due to the gravity-gradient term are considered, and the three-tunnel method proposed by Wilk (1969) is examined. The rotation of the sphere is discussed together with aspects of the reference systems used, the equations of motion of the spacecraft and of the test objects, the field from the earth's gravity gradient at the test object, higher harmonic terms in the gravity gradient force, gravitational effects of the spacecraft itself, and a computer simulation.

  20. Acoustic radiation force on an air bubble and soft fluid spheres in ideal liquids: example of a high-order Bessel beam of quasi-standing waves.

    PubMed

    Mitri, F G

    2009-04-01

    The partial wave series for the scattering of a high-order Bessel beam (HOBB) of acoustic quasi-standing waves by an air bubble and fluid spheres immersed in water and centered on the axis of the beam is applied to the calculation of the acoustic radiation force. A HOBB refers to a type of beam having an axial amplitude null and an azimuthal phase gradient. Radiation force examples obtained through numerical evaluation of the radiation force function are computed for an air bubble, a hexane, a red blood and mercury fluid spheres in water. The examples were selected to illustrate conditions having progressive, standing and quasi-standing waves with appropriate selection of the waves' amplitude ratio. An especially noteworthy result is the lack of a specific vibrational mode contribution to the radiation force determined by appropriate selection of the HOBB parameters.

  1. Marcus equation

    DOE R&D Accomplishments Database

    1998-09-21

    In the late 1950s to early 1960s Rudolph A. Marcus developed a theory for treating the rates of outer-sphere electron-transfer reactions. Outer-sphere reactions are reactions in which an electron is transferred from a donor to an acceptor without any chemical bonds being made or broken. (Electron-transfer reactions in which bonds are made or broken are referred to as inner-sphere reactions.) Marcus derived several very useful expressions, one of which has come to be known as the Marcus cross-relation or, more simply, as the Marcus equation. It is widely used for correlating and predicting electron-transfer rates. For his contributions to the understanding of electron-transfer reactions, Marcus received the 1992 Nobel Prize in Chemistry. This paper discusses the development and use of the Marcus equation. Topics include self-exchange reactions; net electron-transfer reactions; Marcus cross-relation; and proton, hydride, atom and group transfers.

  2. Designing non-Hermitian dynamics for conservative state evolution on the Bloch sphere

    NASA Astrophysics Data System (ADS)

    Yu, Sunkyu; Piao, Xianji; Park, Namkyoo

    2018-03-01

    An evolution on the Bloch sphere is the fundamental state transition, including optical polarization controls and qubit operations. Conventional evolution of a polarization state or qubit is implemented within a closed system that automatically satisfies energy conservation from the Hermitian formalism. Although particular forms of static non-Hermitian Hamiltonians, such as parity-time-symmetric Hamiltonians, allow conservative states in an open system, the criteria for the energy conservation in a dynamical open system have not been fully explored. Here, we derive the condition of conservative state evolution in open-system dynamics and its inverse design method, by developing the non-Hermitian modification of the Larmor precession equation. We show that the geometrically designed locus on the Bloch sphere can be realized by different forms of dynamics, leading to the isolocus family of non-Hermitian dynamics. This increased degree of freedom allows the complementary phenomena of error-robust and highly sensitive evolutions on the Bloch sphere, which could be applicable to stable polarizers, quantum gates, and optimized sensors in dynamical open systems.

  3. SHINE, The SpHere INfrared survey for Exoplanets

    NASA Astrophysics Data System (ADS)

    Chauvin, G.; Desidera, S.; Lagrange, A.-M.; Vigan, A.; Feldt, M.; Gratton, R.; Langlois, M.; Cheetham, A.; Bonnefoy, M.; Meyer, M.

    2017-12-01

    The SHINE survey for SPHERE High-contrast ImagiNg survey for Exoplanets, is a large near-infrared survey of 400-600 young, nearby stars and represents a significant component of the SPHERE consortium Guaranteed Time Observations consisting in 200 observing nights. The scientific goals are: i) to characterize known planetary systems (architecture, orbit, stability, luminosity, atmosphere); ii) to search for new planetary systems using SPHERE's unprecedented performance; and finally iii) to determine the occurrence and orbital and mass function properties of the wide-orbit, giant planet population as a function of the stellar host mass and age. Combined, the results will increase our understanding of planetary atmospheric physics and the processes of planetary formation and evolution.

  4. Structure and effective interactions in three-component hard sphere liquids.

    PubMed

    König, A; Ashcroft, N W

    2001-04-01

    Complete and simple analytical expressions for the partial structure factors of the ternary hard sphere mixture are obtained within the Percus-Yevick approximation and presented as functions of relative packing fractions and relative hard sphere diameters. These solutions follow from the Laplace transform method as applied to multicomponent systems by Lebowitz [Phys. Rev. 133, A895 (1964)]. As an important application, we examine effective interactions in hard sphere liquid mixtures using the microscopic information contained in their partial structure factors. Thus the ensuring pair potential for an effective one-component system is obtained from the correlation functions by using an approximate inversion, and examples of effective potentials for three-component hard sphere mixtures are given. These mixtures may be of particular interest for the study of the packing aspects of melts that form glasses or quasicrystals, since noncrystalline solids often emerge from melts with at least three atomic constituents.

  5. Cryogenic characterization of LEDs for space application

    NASA Astrophysics Data System (ADS)

    Carron, Jérôme; Philippon, Anne; How, Lip Sun; Delbergue, Audrey; Hassanzadeh, Sahar; Cillierre, David; Danto, Pascale; Boutillier, Mathieu

    2017-09-01

    In the frame of EUCLID project, the Calibration Unit of the VIS (VISible Imager) instrument must provide an accurate and well characterized light source for in-flight instrument calibration without noise when it is switched off. The Calibration Unit consists of a set of LEDs emitting at various wavelengths in the visible towards an integrating sphere. The sphere's output provides a uniform illumination over the entire focal plane. Nine references of LEDs from different manufacturers were selected, screened and qualified under cryogenic conditions. Testing this large quantity of samples led to the implementation of automated testing equipment with complete in-situ monitoring of optoelectronic parameters as well as temperature and vacuum values. All the electrical and optical parameters of the LED have been monitored and recorded at ambient and cryogenic temperatures. These results have been compiled in order to show the total deviation of the LED electrical and electro-optical properties in the whole mission and to select the best suitable LED references for the mission. This qualification has demonstrated the robustness of COTS LEDs to operate at low cryogenic temperatures and in the space environment. Then 6 wavelengths were selected and submitted to an EMC sensitivity test at room and cold temperature by counting the number of photons when LEDs drivers are OFF. Characterizations were conducted in the full frequency spectrum in order to implement solutions at system level to suppress the emission of photons when the LED drivers are OFF. LEDs impedance was also characterized at room temperature and cold temperature.

  6. Generation of realistic virtual nodules based on three-dimensional spatial resolution in lung computed tomography: A pilot phantom study.

    PubMed

    Narita, Akihiro; Ohkubo, Masaki; Murao, Kohei; Matsumoto, Toru; Wada, Shinichi

    2017-10-01

    The aim of this feasibility study using phantoms was to propose a novel method for obtaining computer-generated realistic virtual nodules in lung computed tomography (CT). In the proposed methodology, pulmonary nodule images obtained with a CT scanner are deconvolved with the point spread function (PSF) in the scan plane and slice sensitivity profile (SSP) measured for the scanner; the resultant images are referred to as nodule-like object functions. Next, by convolving the nodule-like object function with the PSF and SSP of another (target) scanner, the virtual nodule can be generated so that it has the characteristics of the spatial resolution of the target scanner. To validate the methodology, the authors applied physical nodules of 5-, 7- and 10-mm-diameter (uniform spheres) included in a commercial CT test phantom. The nodule-like object functions were calculated from the sphere images obtained with two scanners (Scanner A and Scanner B); these functions were referred to as nodule-like object functions A and B, respectively. From these, virtual nodules were generated based on the spatial resolution of another scanner (Scanner C). By investigating the agreement of the virtual nodules generated from the nodule-like object functions A and B, the equivalence of the nodule-like object functions obtained from different scanners could be assessed. In addition, these virtual nodules were compared with the real (true) sphere images obtained with Scanner C. As a practical validation, five types of laboratory-made physical nodules with various complicated shapes and heterogeneous densities, similar to real lesions, were used. The nodule-like object functions were calculated from the images of these laboratory-made nodules obtained with Scanner A. From them, virtual nodules were generated based on the spatial resolution of Scanner C and compared with the real images of laboratory-made nodules obtained with Scanner C. Good agreement of the virtual nodules generated from the nodule-like object functions A and B of the phantom spheres was found, suggesting the validity of the nodule-like object functions. The virtual nodules generated from the nodule-like object function A of the phantom spheres were similar to the real images obtained with Scanner C; the root mean square errors (RMSEs) between them were 10.8, 11.1, and 12.5 Hounsfield units (HU) for 5-, 7-, and 10-mm-diameter spheres, respectively. The equivalent results (RMSEs) using the nodule-like object function B were 15.9, 16.8, and 16.5 HU, respectively. These RMSEs were small considering the high contrast between the sphere density and background density (approximately 674 HU). The virtual nodules generated from the nodule-like object functions of the five laboratory-made nodules were similar to the real images obtained with Scanner C; the RMSEs between them ranged from 6.2 to 8.6 HU in five cases. The nodule-like object functions calculated from real nodule images would be effective to generate realistic virtual nodules. The proposed method would be feasible for generating virtual nodules that have the characteristics of the spatial resolution of the CT system used in each institution, allowing for site-specific nodule generation. © 2017 American Association of Physicists in Medicine.

  7. Delivery of chemotherapeutics using spheres made of bioengineered spider silks derived from MaSp1 and MaSp2 proteins.

    PubMed

    Jastrzebska, Katarzyna; Florczak, Anna; Kucharczyk, Kamil; Lin, Yinnan; Wang, Qin; Mackiewicz, Andrzej; Kaplan, David L; Dams-Kozlowska, Hanna

    2018-02-01

    Analysis of the properties and chemotherapeutics delivery potential of spheres made of bioengineered spider silks MS1 and MS2. MS1 and MS2 derived from Nephila clavipes dragline silks - MaSp1 and MaSp2, respectively - formed spheres that were compared in terms of physicochemical properties, cytotoxicity and loading/release of chemotherapeutics. MS2 spheres were more dispersed, smaller, of solid core, of higher beta-sheet structure content, and of opposite (negative) charge than MS1 spheres. Preloaded MS2 showed greater applicability for mitoxantrone, while postloaded for etoposide delivery compared with MS1 spheres. However, MS1 spheres were a better choice for doxorubicin delivery than MS2. Bioengineered silks can be tailored to develop a system with optimal drug loading and release properties.

  8. Phase diagram of heteronuclear Janus dumbbells

    NASA Astrophysics Data System (ADS)

    O'Toole, Patrick; Giacometti, Achille; Hudson, Toby

    Using Aggregation-Volume-Bias Monte Carlo simulations along with Successive Umbrella Sampling and Histogram Re-weighting, we study the phase diagram of a system of dumbbells formed by two touching spheres having variable sizes, as well as different interaction properties. The first sphere ($h$) interacts with all other spheres belonging to different dumbbells with a hard-sphere potential. The second sphere ($s$) interacts via a square-well interaction with other $s$ spheres belonging to different dumbbells and with a hard-sphere potential with all remaining $h$ spheres. We focus on the region where the $s$ sphere is larger than the $h$ sphere, as measured by a parameter $1\\le \\alpha\\le 2 $ controlling the relative size of the two spheres. As $\\alpha \\to 2$ a simple fluid of square-well spheres is recovered, whereas $\\alpha \\to 1$ corresponds to the Janus dumbbell limit, where the $h$ and $s$ spheres have equal sizes. Many phase diagrams falling into three classes are observed, depending on the value of $\\alpha$. The $1.8 \\le \\alpha \\le 2$ is dominated by a gas-liquid phase separation very similar to that of a pure square-well fluid with varied critical temperature and density. When $1.3 \\le \\alpha \\le 1.8$ we find a progressive destabilization of the gas-liquid phase diagram by the onset of self-assembled structures, that eventually lead to a metastability of the gas-liquid transition below $\\alpha=1.2$.

  9. Dual wavelength multiple-angle light scattering system for cryptosporidium detection

    NASA Astrophysics Data System (ADS)

    Buaprathoom, S.; Pedley, S.; Sweeney, S. J.

    2012-06-01

    A simple, dual wavelength, multiple-angle, light scattering system has been developed for detecting cryptosporidium suspended in water. Cryptosporidium is a coccidial protozoan parasite causing cryptosporidiosis; a diarrheal disease of varying severity. The parasite is transmitted by ingestion of contaminated water, particularly drinking-water, but also accidental ingestion of bathing-water, including swimming pools. It is therefore important to be able to detect these parasites quickly, so that remedial action can be taken to reduce the risk of infection. The proposed system combines multiple-angle scattering detection of a single and two wavelengths, to collect relative wavelength angle-resolved scattering phase functions from tested suspension, and multivariate data analysis techniques to obtain characterizing information of samples under investigation. The system was designed to be simple, portable and inexpensive. It employs two diode lasers (violet InGaN-based and red AlGaInP-based) as light sources and silicon photodiodes as detectors and optical components, all of which are readily available. The measured scattering patterns using the dual wavelength system showed that the relative wavelength angle-resolved scattering pattern of cryptosporidium oocysts was significantly different from other particles (e.g. polystyrene latex sphere, E.coli). The single wavelength set up was applied for cryptosporidium oocysts'size and relative refractive index measurement and differential measurement of the concentration of cryptosporidium oocysts suspended in water and mixed polystyrene latex sphere suspension. The measurement results showed good agreement with the control reference values. These results indicate that the proposed method could potentially be applied to online detection in a water quality control system.

  10. Radar Transponder Antenna Systems Evaluation Handbook

    DTIC Science & Technology

    2006-07-01

    Poincare Sphere Usage. The plane geometry... Poincare Sphere any coupling factor is numerically equal to the cosine of half the distance between states on the spherical surface. 5-52 Then in...Erhcp, Elhcp) on the Poincare sphere (Paragraph 5.14.1). As such, any antenna whose polarization lies on this plane receives the same

  11. Experimental study of the oscillation of spheres in an acoustic levitator.

    PubMed

    Andrade, Marco A B; Pérez, Nicolás; Adamowski, Julio C

    2014-10-01

    The spontaneous oscillation of solid spheres in a single-axis acoustic levitator is experimentally investigated by using a high speed camera to record the position of the levitated sphere as a function of time. The oscillations in the axial and radial directions are systematically studied by changing the sphere density and the acoustic pressure amplitude. In order to interpret the experimental results, a simple model based on a spring-mass system is applied in the analysis of the sphere oscillatory behavior. This model requires the knowledge of the acoustic pressure distribution, which was obtained numerically by using a linear finite element method (FEM). Additionally, the linear acoustic pressure distribution obtained by FEM was compared with that measured with a laser Doppler vibrometer. The comparison between numerical and experimental pressure distributions shows good agreement for low values of pressure amplitude. When the pressure amplitude is increased, the acoustic pressure distribution becomes nonlinear, producing harmonics of the fundamental frequency. The experimental results of the spheres oscillations for low pressure amplitudes are consistent with the results predicted by the simple model based on a spring-mass system.

  12. The pair correlation function of krypton in the critical region: theory and experiment

    NASA Astrophysics Data System (ADS)

    Barocchi, F.; Chieux, P.; Fontana, R.; Magli, R.; Meroni, A.; Parola, A.; Reatto, L.; Tau, M.

    1997-10-01

    We present the results of high-precision measurements of the structure factor S(k) of krypton in the near-critical region of the liquid - vapour phase transition for values of k ranging from 1.5 up to 0953-8984/9/42/003/img15. The experimental results are compared with a theoretical calculation based on the hierarchical reference theory (HRT) with an accurate potential which includes two- and three-body contributions. The theory is based on a new implementation of HRT in which we avoid the use of hard spheres as a reference system. With this soft-core formulation we find a generally good agreement with experiments both at large k, where S(k) probes the short-range correlations, as well as at small k, where critical fluctuations become dominant. Also, for the density derivative of the pair correlation function there is an overall good agreement between theory and experiment.

  13. Thermodynamics properties of lanthanide series near melting point-A pseudopotential approach

    NASA Astrophysics Data System (ADS)

    Suthar, P. H.; Gajjar, P. N.

    2018-04-01

    The present paper deals with computational study of thermodynamics properties for fifteen elements of lanthanide series. The Helmholtz free energy (F), Internal energy (E) and Entropy (S)have been computed using variational method based on the Gibbs-Bogoliubov (GB) along with Percus-Yevick hard sphere reference system and Gajjar's model potential. The local field correction function proposed by Taylor is applied to introduce the exchange and correlation effects in the study of thermodynamics of these metals. The present results in comparison with available theoretical and experimental are found to be in good agreement and confirm the ability of the model potential.

  14. American Mathematics from 1940 to the Day Before Yesterday

    ERIC Educational Resources Information Center

    Ewing, J. H.; And Others

    1976-01-01

    Ten recent results in pure mathematics are described, covering the continuum hypothesis, Diophantine equations, simple groups, resolution of singularities, Weil conjectures, Lie groups, Poincare conjecture, exotic spheres, differential equations, and the index theorem. Proofs are omitted, but references are provided. (DT)

  15. A convenient technique for polarimetric calibration of single-antenna radar systems

    NASA Technical Reports Server (NTRS)

    Sarabandi, Kamal; Ulaby, Fawwaz T.

    1990-01-01

    A practical technique for calibrating single-antenna polarimetric radar systems is introduced. This technique requires only a single calibration target such as a conducting sphere or a trihedral corner reflector to calibrate the radar system, both in amplitude and phase, for all linear polarization configurations. By using a metal sphere, which is orientation independent, error in calibration measurement is minimized while simultaneously calibrating the crosspolarization channels. The antenna system and two orthogonal channels (in free space) are modeled as a four-port passive network. Upon using the reciprocity relations for the passive network and assuming the crosscoupling terms of the antenna to be equal, the crosstalk factors of the antenna system and the transmit and receive channel imbalances can be obtained from measurement of the backscatter from a metal sphere. For an X-band radar system with crosspolarization isolation of 25 dB, comparison of values measured for a sphere and a cylinder with theoretical values shows agreement within 0.4 dB in magnitude and 5 deg in phase. An effective polarization isolation of 50 dB is achieved using this calibration technique.

  16. Analysis of the Reference Systems of Modern Selenographic Systems

    NASA Astrophysics Data System (ADS)

    Nefedyev, Yuri; Petrova, Natalia; Andreev, Alexey; Demina, Natalya

    2016-07-01

    In this work analysis of the reference systems of modern selenographic systems was made. The center of the Moon's mass position relative to its center of figure was determined from the data of "Clementine" and "Kaguya" missions and "ULCN" and "KSC-1162" catalogues. The knowledge of the Moon's center of mass position relative to its center of figure is important for researches of the lunar origin, structure and evolution and in terms of precision solutions circumlunar navigation tasks. At the present this task is the most relevant and demanded for cosmic lunar missions.The expansions by spherical harmonics N=5 degree and order of the lunar function h (λ, β) using the package ASNI USTU were executed. Module of the expansion of the local area to surfaces to full sphere was used. The parameters of cosmic missions are given for comparison (SAI; Bills, Ferrari). The normalized coefficients from expansions for eight sources of hypsometric information are obtained: "Clementine" (N=40), "KSC-1162" (N=5), "Kiev" (N=5), "SAI" (N=10; Chuikova (1975)), "Bills, Ferrari", "Kaguya" (Selena, Japan mission), "ULCN" (The Unified Lunar Control Network 2005). The displacements of the lunar center of figure relative to the lunar center of the mass were defined from equations (Chuikova (1975)): Δ ξ = C_{11} √{3}, Δ η= S_{11} √{3}, Δ ζ = C_{10} √{3}, where ξ is the axis directed towards the Earth, η is equatorial axis directed perpendicularly to ξ , ζ is rotation axis of the Moon, C_{11} , S_{11} , C_{10} are the normalized amplitudes of the harmonics of the first order expansion of the relief. After that we considered: - mathematical models in the form of expansions in spherical functions - methods for estimating the model parameters; - information technology data processing. As a model describing the behavior of the relief on the lunar sphere is used the expansion of the height in a series of spherical harmonics (Sagitov (1979)) in the form of a regression model (Valeev (2001)). To obtain the expansions in spherical harmonics in order to create a digital model and determine estimations of the center of mass position of the Moon relative to its center of the figure required in the future was usedsoftware package ASSR "Sphere" (an automated system of scientific research).ASSR "Sphere" is intended to describe the distribution of various values of the parameters (topography, gravity, magnetic, and other types of potential fields) on the sphere and its parts which were measured in points with known coordinates. Using this bundled software one can generate models of the specificform,carry out forecasting in the form of cross-sections, contour, tone and three-dimensional representation of the distribution of characteristicsvalues. The formation of models is accompanied by estimation of their quality and diagnostic of adherence of least square method. After all we can conclude that the "KSC-1162" catalogue, which was obtained in the center of mass and principal axes of inertia of the Moon, has the closest agreement with the results of recent space missions.It should be noted that the correction of the first measurements of the "Clementine" mission data, which were obtained by the authors of the "ULCN 2005" catalogue, was apparently related to the data on the visible side of the Moon because the amplitudes and offsets for the ("KSC-1162" + "Clementine") option close to the results of the "ULCN 2005" optionbut not to"Clementine".The results of defining relative position of the lunar center of mass and center of figure in "KSC-1162"selenocentric catalogue gave some good agreement with modern space mission data. Work was supported by grants RFBR 15-02-01638-a, 16-32-60071-mol-dk-a and 16-02-00496-a.

  17. Review on the Celestial Sphere Positioning of FITS Format Image Based on WCS and Research on General Visualization

    NASA Astrophysics Data System (ADS)

    Song, W. M.; Fan, D. W.; Su, L. Y.; Cui, C. Z.

    2017-11-01

    Calculating the coordinate parameters recorded in the form of key/value pairs in FITS (Flexible Image Transport System) header is the key to determine FITS images' position in the celestial system. As a result, it has great significance in researching the general process of calculating the coordinate parameters. By combining CCD related parameters of astronomical telescope (such as field, focal length, and celestial coordinates in optical axis, etc.), astronomical images recognition algorithm, and WCS (World Coordinate System) theory, the parameters can be calculated effectively. CCD parameters determine the scope of star catalogue, so that they can be used to build a reference star catalogue by the corresponding celestial region of astronomical images; Star pattern recognition completes the matching between the astronomical image and reference star catalogue, and obtains a table with a certain number of stars between CCD plane coordinates and their celestial coordinates for comparison; According to different projection of the sphere to the plane, WCS can build different transfer functions between these two coordinates, and the astronomical position of image pixels can be determined by the table's data we have worked before. FITS images are used to carry out scientific data transmission and analyze as a kind of mainstream data format, but only to be viewed, edited, and analyzed in the professional astronomy software. It decides the limitation of popular science education in astronomy. The realization of a general image visualization method is significant. FITS is converted to PNG or JPEG images firstly. The coordinate parameters in the FITS header are converted to metadata in the form of AVM (Astronomy Visualization Metadata), and then the metadata is added to the PNG or JPEG header. This method can meet amateur astronomers' general needs of viewing and analyzing astronomical images in the non-astronomical software platform. The overall design flow is realized through the java program and tested by SExtractor, WorldWide Telescope, picture viewer, and other software.

  18. Hopkins with SPHERES RINGS

    NASA Image and Video Library

    2013-11-04

    ISS037-E-025870 (4 Nov. 2013) --- In the International Space Station?s Kibo laboratory, NASA astronaut Michael Hopkins, Expedition 37 flight engineer, conducts a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  19. Hopkins with SPHERES RINGS

    NASA Image and Video Library

    2013-11-04

    ISS037-E-025868 (4 Nov. 2013) --- In the International Space Station?s Kibo laboratory, NASA astronaut Michael Hopkins, Expedition 37 flight engineer, conducts a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  20. DOD SPHERES-RINGS Test Session

    NASA Image and Video Library

    2013-11-04

    ISS037-E-025915 (4 Nov. 2013) --- In the International Space Station?s Kibo laboratory, NASA astronaut Michael Hopkins, Expedition 37 flight engineer, conducts a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  1. Hopkins with SPHERES RINGS

    NASA Image and Video Library

    2013-11-04

    ISS037-E-025866 (4 Nov. 2013) --- In the International Space Station?s Kibo laboratory, NASA astronaut Michael Hopkins, Expedition 37 flight engineer, conducts a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  2. Hopkins with SPHERES RINGS

    NASA Image and Video Library

    2013-11-04

    ISS037-E-025872 (4 Nov. 2013) --- In the International Space Station?s Kibo laboratory, NASA astronaut Michael Hopkins, Expedition 37 flight engineer, conducts a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  3. Hopkins with SPHERES RINGS

    NASA Image and Video Library

    2013-11-04

    ISS037-E-025879 (4 Nov. 2013) --- In the International Space Station?s Kibo laboratory, NASA astronaut Michael Hopkins, Expedition 37 flight engineer, conducts a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Margaret A. Marshall

    In the early 1970’s Dr. John T. Mihalczo (team leader), J.J. Lynn, and J.R. Taylor performed experiments at the Oak Ridge Critical Experiments Facility (ORCEF) with highly enriched uranium (HEU) metal (called Oak Ridge Alloy or ORALLOY) in an attempt to recreate GODIVA I results with greater accuracy than those performed at Los Alamos National Laboratory in the 1950’s (HEU-MET-FAST-001). The purpose of the Oak Ridge ORALLOY Sphere (ORSphere) experiments was to estimate the unreflected and unmoderated critical mass of an idealized sphere of uranium metal corrected to a density, purity, and enrichment such that it could be compared withmore » the GODIVA I experiments. “The very accurate description of this sphere, as assembled, establishes it as an ideal benchmark for calculational methods and cross-section data files.” (Reference 1) While performing the ORSphere experiments care was taken to accurately document component dimensions (±0. 0001 in. for non-spherical parts), masses (±0.01 g), and material data The experiment was also set up to minimize the amount of structural material in the sphere proximity. A three part sphere was initially assembled with an average radius of 3.4665 in. and was then machined down to an average radius of 3.4420 in. (3.4425 in. nominal). These two spherical configurations were evaluated and judged to be acceptable benchmark experiments; however, the two experiments are highly correlated.« less

  5. Phononic crystals of spherical particles: A tight binding approach

    NASA Astrophysics Data System (ADS)

    Mattarelli, M.; Secchi, M.; Montagna, M.

    2013-11-01

    The vibrational dynamics of a fcc phononic crystal of spheres is studied and compared with that of a single free sphere, modelled either by a continuous homogeneous medium or by a finite cluster of atoms. For weak interaction among the spheres, the vibrational dynamics of the phononic crystal is described by shallow bands, with low degree of dispersion, corresponding to the acoustic spheroidal and torsional modes of the single sphere. The phonon displacements are therefore related to the vibrations of a sphere, as the electron wave functions in a crystal are related to the atomic wave functions in a tight binding model. Important dispersion is found for the two lowest phonon bands, which correspond to zero frequency free translation and rotation of a free sphere. Brillouin scattering spectra are calculated at some values of the exchanged wavevectors of the light, and compared with those of a single sphere. With weak interaction between particles, given the high acoustic impedance mismatch in dry systems, the density of phonon states consist of sharp bands separated by large gaps, which can be well accounted for by a single particle model. Based on the width of the frequency gaps, tunable with the particle size, and on the small number of dispersive acoustic phonons, such systems may provide excellent materials for application as sound or heat filters.

  6. Methods and considerations to determine sphere center from terrestrial laser scanner point cloud data

    NASA Astrophysics Data System (ADS)

    Rachakonda, Prem; Muralikrishnan, Bala; Cournoyer, Luc; Cheok, Geraldine; Lee, Vincent; Shilling, Meghan; Sawyer, Daniel

    2017-10-01

    The Dimensional Metrology Group at the National Institute of Standards and Technology is performing research to support the development of documentary standards within the ASTM E57 committee. This committee is addressing the point-to-point performance evaluation of a subclass of 3D imaging systems called terrestrial laser scanners (TLSs), which are laser-based and use a spherical coordinate system. This paper discusses the usage of sphere targets for this effort, and methods to minimize the errors due to the determination of their centers. The key contributions of this paper include methods to segment sphere data from a TLS point cloud, and the study of some of the factors that influence the determination of sphere centers.

  7. Sensitive detection of methane at 3.3 μm using an integrating sphere and interband cascade laser

    NASA Astrophysics Data System (ADS)

    Davis, N. M.; Hodgkinson, J.; Francis, D.; Tatam, R. P.

    2016-04-01

    Detection of methane at 3.3μm using a DFB Interband Cascade Laser and gold coated integrating sphere is performed. A 10cm diameter sphere with effective path length of 54.5cm was adapted for use as a gas cell. A comparison between this system and one using a 25cm path length single-pass gas cell is made using direct TDLS and methane concentrations between 0 and 1000 ppm. Initial investigations suggest a limit of detection of 1.0ppm for the integrating sphere and 2.2ppm for the single pass gas cell. The system has potential applications in challenging or industrial environments subject to high levels of vibration.

  8. Interaction and charge transfer between dielectric spheres: Exact and approximate analytical solutions.

    PubMed

    Lindén, Fredrik; Cederquist, Henrik; Zettergren, Henning

    2016-11-21

    We present exact analytical solutions for charge transfer reactions between two arbitrarily charged hard dielectric spheres. These solutions, and the corresponding exact ones for sphere-sphere interaction energies, include sums that describe polarization effects to infinite orders in the inverse of the distance between the sphere centers. In addition, we show that these exact solutions may be approximated by much simpler analytical expressions that are useful for many practical applications. This is exemplified through calculations of Langevin type cross sections for forming a compound system of two colliding spheres and through calculations of electron transfer cross sections. We find that it is important to account for dielectric properties and finite sphere sizes in such calculations, which for example may be useful for describing the evolution, growth, and dynamics of nanometer sized dielectric objects such as molecular clusters or dust grains in different environments including astrophysical ones.

  9. Correction factors for the ISO rod phantom, a cylinder phantom, and the ICRU sphere for reference beta radiation fields of the BSS 2

    NASA Astrophysics Data System (ADS)

    Behrens, R.

    2015-03-01

    The International Organization for Standardization (ISO) requires in its standard ISO 6980 that beta reference radiation fields for radiation protection be calibrated in terms of absorbed dose to tissue at a depth of 0.07 mm in a slab phantom (30 cm x 30 cm x 15 cm). However, many beta dosemeters are ring dosemeters and are, therefore, irradiated on a rod phantom (1.9 cm in diameter and 30 cm long), or they are eye dosemeters possibly irradiated on a cylinder phantom (20 cm in diameter and 20 cm high), or area dosemeters irradiated free in air with the conventional quantity value (true value) being defined in a sphere (30 cm in diameter, made of ICRU tissue (International Commission on Radiation Units and Measurements)). Therefore, the correction factors for the conventional quantity value in the rod, the cylinder, and the sphere instead of the slab (all made of ICRU tissue) were calculated for the radiation fields of 147Pm, 85Kr, 90Sr/90Y, and, 106Ru/106Rh sources of the beta secondary standard BSS 2 developed at PTB. All correction factors were calculated for 0° up to 75° (in steps of 15°) radiation incidence. The results are ready for implementation in ISO 6980-3 and have recently been (partly) implemented in the software of the BSS 2.

  10. Development and validation of a multilateration test bench for particle accelerator pre-alignment

    NASA Astrophysics Data System (ADS)

    Kamugasa, Solomon William; Rothacher, Markus; Gayde, Jean-Christophe; Mainaud Durand, Helene

    2018-03-01

    The development and validation of a portable coordinate measurement solution for fiducialization of compact linear collider (CLIC) components is presented. This new solution addresses two limitations of high-accuracy state-of-the-art coordinate measuring machines, i.e. lack of portability and limited measurement volume. The solution is based on frequency scanning interferometry (FSI) distances and the multilateration coordinate measurement technique. The developments include a reference sphere for localizing the FSI optical fiber tip and a kinematic mount for repositioning the reference sphere with sub-micrometric repeatability. This design enables absolute distance measurements in different directions from the same point, which is essential for multilateration. A multilateration test bench built using these prototypes has been used to fiducialize a CLIC cavity beam position monitor and 420 mm-long main beam quadrupole magnet. The combined fiducialization uncertainty achieved is 3.5 μm (k  =  1), which is better than the CLIC 5 μm (k  =  1) uncertainty specification.

  11. An Ancient Relation between Units of Length and Volume Based on a Sphere

    PubMed Central

    Zapassky, Elena; Gadot, Yuval; Finkelstein, Israel; Benenson, Itzhak

    2012-01-01

    The modern metric system defines units of volume based on the cube. We propose that the ancient Egyptian system of measuring capacity employed a similar concept, but used the sphere instead. When considered in ancient Egyptian units, the volume of a sphere, whose circumference is one royal cubit, equals half a hekat. Using the measurements of large sets of ancient containers as a database, the article demonstrates that this formula was characteristic of Egyptian and Egyptian-related pottery vessels but not of the ceramics of Mesopotamia, which had a different system of measuring length and volume units. PMID:22470489

  12. Characterising exoplanet atmospheres with SPHERE: the HR 8799 system with Exo-REM and NEMESIS

    NASA Astrophysics Data System (ADS)

    Baudino, J.-L.; Bonnefoy, M.; Vigan, A.; Irwin, P. J.

    2017-12-01

    The characterisation of the exoplanets evolved recently thanks to the beginning of the second generation of direct imaging instruments, especially with SPHERE. The resolution and wavelength range available currently give access to an increase of accuracy and on the number of physical parameters that can be constrain. One of the first target of SPHERE was the HR 8799 system. The four planets was characterised using four different forward models including Exo-REM. We complete this paper buy using NEMESIS, a retrieval code.

  13. A hardware investigation of robotic SPECT for functional and molecular imaging onboard radiation therapy systems

    PubMed Central

    Yan, Susu; Bowsher, James; Tough, MengHeng; Cheng, Lin; Yin, Fang-Fang

    2014-01-01

    Purpose: To construct a robotic SPECT system and to demonstrate its capability to image a thorax phantom on a radiation therapy flat-top couch, as a step toward onboard functional and molecular imaging in radiation therapy. Methods: A robotic SPECT imaging system was constructed utilizing a gamma camera detector (Digirad 2020tc) and a robot (KUKA KR150 L110 robot). An imaging study was performed with a phantom (PET CT PhantomTM), which includes five spheres of 10, 13, 17, 22, and 28 mm diameters. The phantom was placed on a flat-top couch. SPECT projections were acquired either with a parallel-hole collimator or a single-pinhole collimator, both without background in the phantom and with background at 1/10th the sphere activity concentration. The imaging trajectories of parallel-hole and pinhole collimated detectors spanned 180° and 228°, respectively. The pinhole detector viewed an off-centered spherical common volume which encompassed the 28 and 22 mm spheres. The common volume for parallel-hole system was centered at the phantom which encompassed all five spheres in the phantom. The maneuverability of the robotic system was tested by navigating the detector to trace the phantom and flat-top table while avoiding collision and maintaining the closest possible proximity to the common volume. The robot base and tool coordinates were used for image reconstruction. Results: The robotic SPECT system was able to maneuver parallel-hole and pinhole collimated SPECT detectors in close proximity to the phantom, minimizing impact of the flat-top couch on detector radius of rotation. Without background, all five spheres were visible in the reconstructed parallel-hole image, while four spheres, all except the smallest one, were visible in the reconstructed pinhole image. With background, three spheres of 17, 22, and 28 mm diameters were readily observed with the parallel-hole imaging, and the targeted spheres (22 and 28 mm diameters) were readily observed in the pinhole region-of-interest imaging. Conclusions: Onboard SPECT could be achieved by a robot maneuvering a SPECT detector about patients in position for radiation therapy on a flat-top couch. The robot inherent coordinate frames could be an effective means to estimate detector pose for use in SPECT image reconstruction. PMID:25370663

  14. A hardware investigation of robotic SPECT for functional and molecular imaging onboard radiation therapy systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yan, Susu, E-mail: susu.yan@duke.edu; Tough, MengHeng; Bowsher, James

    Purpose: To construct a robotic SPECT system and to demonstrate its capability to image a thorax phantom on a radiation therapy flat-top couch, as a step toward onboard functional and molecular imaging in radiation therapy. Methods: A robotic SPECT imaging system was constructed utilizing a gamma camera detector (Digirad 2020tc) and a robot (KUKA KR150 L110 robot). An imaging study was performed with a phantom (PET CT Phantom{sup TM}), which includes five spheres of 10, 13, 17, 22, and 28 mm diameters. The phantom was placed on a flat-top couch. SPECT projections were acquired either with a parallel-hole collimator ormore » a single-pinhole collimator, both without background in the phantom and with background at 1/10th the sphere activity concentration. The imaging trajectories of parallel-hole and pinhole collimated detectors spanned 180° and 228°, respectively. The pinhole detector viewed an off-centered spherical common volume which encompassed the 28 and 22 mm spheres. The common volume for parallel-hole system was centered at the phantom which encompassed all five spheres in the phantom. The maneuverability of the robotic system was tested by navigating the detector to trace the phantom and flat-top table while avoiding collision and maintaining the closest possible proximity to the common volume. The robot base and tool coordinates were used for image reconstruction. Results: The robotic SPECT system was able to maneuver parallel-hole and pinhole collimated SPECT detectors in close proximity to the phantom, minimizing impact of the flat-top couch on detector radius of rotation. Without background, all five spheres were visible in the reconstructed parallel-hole image, while four spheres, all except the smallest one, were visible in the reconstructed pinhole image. With background, three spheres of 17, 22, and 28 mm diameters were readily observed with the parallel-hole imaging, and the targeted spheres (22 and 28 mm diameters) were readily observed in the pinhole region-of-interest imaging. Conclusions: Onboard SPECT could be achieved by a robot maneuvering a SPECT detector about patients in position for radiation therapy on a flat-top couch. The robot inherent coordinate frames could be an effective means to estimate detector pose for use in SPECT image reconstruction.« less

  15. Normal modes of the shallow water system on the cubed sphere

    NASA Astrophysics Data System (ADS)

    Kang, H. G.; Cheong, H. B.; Lee, C. H.

    2017-12-01

    Spherical harmonics expressed as the Rossby-Haurwitz waves are the normal modes of non-divergent barotropic model. Among the normal modes in the numerical models, the most unstable mode will contaminate the numerical results, and therefore the investigation of normal mode for a given grid system and a discretiztaion method is important. The cubed-sphere grid which consists of six identical faces has been widely adopted in many atmospheric models. This grid system is non-orthogonal grid so that calculation of the normal mode is quiet challenge problem. In the present study, the normal modes of the shallow water system on the cubed sphere discretized by the spectral element method employing the Gauss-Lobatto Lagrange interpolating polynomials as orthogonal basis functions is investigated. The algebraic equations for the shallow water equation on the cubed sphere are derived, and the huge global matrix is constructed. The linear system representing the eigenvalue-eigenvector relations is solved by numerical libraries. The normal mode calculated for the several horizontal resolution and lamb parameters will be discussed and compared to the normal mode from the spherical harmonics spectral method.

  16. End-State Relative Equilibria in the Sphere-Restricted Full Three-Body Problem

    NASA Astrophysics Data System (ADS)

    Gabriel, Travis; Scheeres, Daniel J.

    2015-05-01

    The Sphere-Restricted Full Three-Body Problem studies the motion of three finite density spheres as they interact under surface and gravitational forces. When accounting for the dissipation of energy, full-body systems may achieve minimum energy states that are unatainable in the classic treatment of the N-Body Problem. This serves as a simple model for the mechanics of rubble pile asteroids, interacting grains in a protoplanetary disk, and potentially the interactions of planetary ring particles. Previous studies of this problem have been performed in the case where the three spheres are of equal size and mass, with all possible relative equilibria and their stability having been identified as a function of the total angular momentum of the system. These studies uncovered that at certain levels of angular momentum there exists more than one stable relative equilibrium state. Thus a question of interest is which of these states a dissipative system would preferentially settle in provided some domain of initial conditions, and whether this would be a function of the dissipation parameters. Using perfectly-rigid dynamics, three-equal-sphere systems are simulated in a purpose-written C-based code to uncover these details. Results from this study are relevant to the mechanics and dynamics in small solar system bodies where relative forces are not great enough to compromise the rigidity of the constituents.

  17. Revealing Secrets of Triple Asteroid Systems with SPHERE

    NASA Astrophysics Data System (ADS)

    Yang, Bin; Wahhaj, Zahed; Beauvalet, Laurene; Marchis, Franck; Dumas, Christophe; Marsset, Michaël

    2015-11-01

    A multiple-asteroid system provides otherwise unattainable information about the intrinsic properties of the system itself as well as its formation and evolution. Comparative spectroscopy and imaging of two large multiple main-belt asteroids: (93) Minerva and (130) Elektra were performed using the newly commissioned Spectro-Polarimetric High-contrast Exoplanet Research instrument (SPHERE) on ESO's 8.2-m VLT. A new moon (S/2014 (130) 1), of the known binary asteroid (130) Elektra, was discovered based on the SPHERE observations, making (130) Elektra the sixth triple system detected in the asteroid belt. We will present the component-resolved near infrared spectra, from 0.9 to 1.6 micron, of the Minerva and the Elektra triple systems. We will also present the orbital solution and the dynamical simulations on the two moons of (130) Elektra.

  18. The steady and transient motion of a sphere through a viscoelastic fluid

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arigo, M.T.; McKinley, G.H.

    1994-12-31

    The settling motion of a sphere along the centerline of a cylindrical tube filled with a viscoelastic fluid is examined experimentally to quantify both the initial transient acceleration from rest and the ultimate steady state motion. A digital imaging system is used to determine the initial transient behavior of the sphere, and a laser Doppler velocimetry (LDV) system is used to independently measure the velocity of the fluid along the centerline of the cylinder as the sphere falls at its ultimate settling velocity. The motion of the sphere is a sensitive function of the dimensionless ratio of the sphere tomore » tube radii a/R and the dimensionless parameter called the Deborah number De. In this study, the authors extend the previous work of Becker et al. (1994), who examined a single ratio of a/R = 0.243, by considering a smaller aspect ratio of a/R = 0.121. Deborah numbers in the range 0.767 {le} De {le} 8.366 were obtained and experimental results who transient velocity over shoots of up to fifty percent of the final constant settling velocity at high De. comparison of the steady state velocity of the sphere in a non-Newtonian fluid to the theoretically-predicted stokes settling velocity reveals an initial drag reduction for low values of De followed by a drag enhancement at high De. LDV measurements in the viscoelastic fluid for both aspect ratios indicate a flow field in which the fore/aft symmetry is broken with the velocity profile in the wake of the sphere extending up to 50 radii behind the sphere at high De.« less

  19. Light collection optics for measuring flux and spectrum from light-emitting devices

    DOEpatents

    McCord, Mark A.; DiRegolo, Joseph A.; Gluszczak, Michael R.

    2016-05-24

    Systems and methods for accurately measuring the luminous flux and color (spectra) from light-emitting devices are disclosed. An integrating sphere may be utilized to directly receive a first portion of light emitted by a light-emitting device through an opening defined on the integrating sphere. A light collector may be utilized to collect a second portion of light emitted by the light-emitting device and direct the second portion of light into the integrating sphere through the opening defined on the integrating sphere. A spectrometer may be utilized to measure at least one property of the first portion and the second portion of light received by the integrating sphere.

  20. Establishment of prostate cancer spheres from a prostate cancer cell line after phenethyl isothiocyanate treatment and discovery of androgen-dependent reversible differentiation between sphere and neuroendocrine cells.

    PubMed

    Chen, Yamei; Cang, Shundong; Han, Liying; Liu, Christina; Yang, Patrick; Solangi, Zeeshan; Lu, Quanyi; Liu, Delong; Chiao, J W

    2016-05-03

    Prostate cancer can transform from androgen-responsive to an androgen-independent phenotype. The mechanism responsible for the transformation remains unclear. We studied the effects of an epigenetic modulator, phenethyl isothiocyanate (PEITC), on the androgen-responsive LNCaP cells. After treatment with PEITC, floating spheres were formed with characteristics of prostate cancer stem cells (PCSC). These spheres were capable of self-renewal in media with and without androgen. They have been maintained in both types of media as long term cultures. Upon androgen deprivation, the adherent spheres differentiated to neuroendocrine cells (NEC) with decreased proliferation, expression of androgen receptor, and PSA. NEC reverse differentiated to spheres when androgen was replenished. The sphere cells expressed surface marker CD44 and had enhanced histone H3K4 acetylation, DNMT1 down-regulation and GSTP1 activation. We hypothesize that PEITC-mediated alteration in epigenomics of LNCaP cells may give rise to sphere cells, whereas reversible androgenomic alterations govern the shuttling between sphere PCSC and progeny NEC. Our findings identify unrecognized properties of prostate cancer sphere cells with multi-potential plasticity. This system will facilitate development of novel therapeutic agents and allow further exploration into epigenomics and androgenomics governing the transformation to hormone refractory prostate cancer.

  1. Interaction of a shock wave with multiple spheres suspended in different arrangements

    NASA Astrophysics Data System (ADS)

    Zhang, Li-Te; Sui, Zhen-Zhen; Shi, Hong-Hui

    2018-03-01

    In this study, the unsteady drag force, Fd, drag coefficient, Cd, and the relevant dynamic behaviors of waves caused by the interaction between a planar incident shock wave and a multi-sphere model are investigated by using imbedded accelerometers and a high-speed Schlieren system. The shock wave is produced in a horizontal 200 mm inner diameter circular shock tube with a 2000 mm × 200 mm × 200 mm transparent test section. The time history of Cd is obtained based on band-block and low-pass Fast Fourier Transformation filtering combined with Savitzky-Golay polynomial smoothing for the measured acceleration. The effects of shock Mach number, Ms, geometry of multi-sphere model, nondimensional distance between sphere centers, H, and channel blockage are analyzed. We find that all time histories of Cd have a similar double-peak shaped main structure. It is due to wave reflection, diffraction, interference, and convergence at different positions of the spheres. The peak Fd increases, whereas the peak Cd decreases monotonically with increasing Ms. The increase of shock strength due to shock focusing by upstream spheres increases the peak Fd of downstream spheres. Both the increase in sphere number and the decrease in distance between spheres promote wave interference between neighboring spheres. As long as the wave interference times are shorter than the peak times, the peak Fd and Cd are higher compared to a single sphere.

  2. METHOD AND APPARATUS FOR DETERMINING CHARGED PARTICLE MOTION

    DOEpatents

    Kerns, Q.A.

    1959-08-01

    An analog system for determining the motion of charged particles in three dimensional electrical fields is described. A model electrode structure is formed and potentials are applied to the electrodes to provide an analog of the field which is to be studied. To simulate charged particles within the model, conducting spheres are placed at points from which particle motion is to be traced. To free the spheres from gravitational attraction in order that they will be electrostatically accelerated through the model, the apparatus is suspended and dropped. During the pericd that the model is dropping the spheres move through the electrcde structure with a motion corresponding to that of particles in the real system. The model is photographed in the course of falling so that the instantaneous position of the spheres within the simulated field at selected times may be observed and measured. The device thus gives data of particles in the real system. The model is photographed in the course of falling so that the instantaneous position of the spheres within the simulated field at selected times may be observed and measured. The device thus gives data which frequently can otherwise be obtained only with a digital computer.

  3. Spheres of discharge of springs

    NASA Astrophysics Data System (ADS)

    Springer, Abraham E.; Stevens, Lawrence E.

    2009-02-01

    Although springs have been recognized as important, rare, and globally threatened ecosystems, there is as yet no consistent and comprehensive classification system or common lexicon for springs. In this paper, 12 spheres of discharge of springs are defined, sketched, displayed with photographs, and described relative to their hydrogeology of occurrence, and the microhabitats and ecosystems they support. A few of the spheres of discharge have been previously recognized and used by hydrogeologists for over 80 years, but others have only recently been defined geomorphologically. A comparison of these spheres of discharge to classification systems for wetlands, groundwater dependent ecosystems, karst hydrogeology, running waters, and other systems is provided. With a common lexicon for springs, hydrogeologists can provide more consistent guidance for springs ecosystem conservation, management, and restoration. As additional comprehensive inventories of the physical, biological, and cultural characteristics are conducted and analyzed, it will eventually be possible to associate spheres of discharge with discrete vegetation and aquatic invertebrate assemblages, and better understand the habitat requirements of rare or unique springs species. Given the elevated productivity and biodiversity of springs, and their highly threatened status, identification of geomorphic similarities among spring types is essential for conservation of these important ecosystems.

  4. SPHERES-RINGS Time Lapse

    NASA Image and Video Library

    2014-07-10

    ISS040-E-059344 (10 July 2014) --- In the International Space Station’s Kibo laboratory, NASA astronaut Reid Wiseman (left) and European Space Agency astronaut Alexander Gerst, both Expedition 40 flight engineers, conduct a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  5. SPHERES-RINGS Time Lapse

    NASA Image and Video Library

    2014-07-10

    ISS040-E-059467 (10 July 2014) --- In the International Space Station's Kibo laboratory, European Space Agency astronaut Alexander Gerst and NASA astronaut Reid Wiseman (mostly obscured), both Expedition 40 flight engineers, conduct a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  6. SPHERES-RINGS Time Lapse

    NASA Image and Video Library

    2014-07-10

    ISS040-E-059478 (10 July 2014) --- In the International Space Station's Kibo laboratory, European Space Agency astronaut Alexander Gerst (left) and NASA astronaut Reid Wiseman, both Expedition 40 flight engineers, conduct a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites is ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS. SPHERES-RINGS seeks to demonstrate wireless power transfer between satellites at a distance for enhanced operations.

  7. Triassico: A Sphere Positioning System for Surface Studies with IBA Techniques

    NASA Astrophysics Data System (ADS)

    Fontana, Cristiano L.; Doyle, Barney L.

    We propose here a novel device, called the Triassico, to microscopically study the entire surface of millimeter-sized spheres. The sphere dimensions can be as small as 1 mm, and the upper limit defined only by the power and by the mechanical characteristics of the motors used. Three motorized driving rods are arranged so an equilateral triangle is formed by the rod's axes, on such a triangle the sphere sits. Movement is achieved by rotating the rods with precise relative speeds and by exploiting the friction between the sphere and the rods surfaces. The sphere can be held in place by gravity or by an opposing trio of rods. By rotating the rods with specific relative angular velocities, a net torque can be exerted on the sphere which then rotates. No repositioning of the sphere or of the motors is needed to cover the full surface with the investigating tools. An algorithm was developed to position the sphere at any arbitrary polar and azimuthal angle. The algorithm minimizes the number of rotations needed by the rods, in order to efficiently select a particular position on the sphere surface. A prototype Triassico was developed for the National Ignition Facility, of the Lawrence Livermore National Laboratory (Livermore, California, USA), as a sphere manipulation apparatus for ion microbeam analysis at Sandia National Laboratories (Albuquerque, NM, USA) of Xe-doped DT inertial confinement fusion fuel spheres. Other applications span from samples orientation, ball bearing manufacturing, or jewelry.

  8. Facilitating Cohort Discovery by Enhancing Ontology Exploration, Query Management and Query Sharing for Large Clinical Data Repositories.

    PubMed

    Tao, Shiqiang; Cui, Licong; Wu, Xi; Zhang, Guo-Qiang

    2017-01-01

    To help researchers better access clinical data, we developed a prototype query engine called DataSphere for exploring large-scale integrated clinical data repositories. DataSphere expedites data importing using a NoSQL data management system and dynamically renders its user interface for concept-based querying tasks. DataSphere provides an interactive query-building interface together with query translation and optimization strategies, which enable users to build and execute queries effectively and efficiently. We successfully loaded a dataset of one million patients for University of Kentucky (UK) Healthcare into DataSphere with more than 300 million clinical data records. We evaluated DataSphere by comparing it with an instance of i2b2 deployed at UK Healthcare, demonstrating that DataSphere provides enhanced user experience for both query building and execution.

  9. Facilitating Cohort Discovery by Enhancing Ontology Exploration, Query Management and Query Sharing for Large Clinical Data Repositories

    PubMed Central

    Tao, Shiqiang; Cui, Licong; Wu, Xi; Zhang, Guo-Qiang

    2017-01-01

    To help researchers better access clinical data, we developed a prototype query engine called DataSphere for exploring large-scale integrated clinical data repositories. DataSphere expedites data importing using a NoSQL data management system and dynamically renders its user interface for concept-based querying tasks. DataSphere provides an interactive query-building interface together with query translation and optimization strategies, which enable users to build and execute queries effectively and efficiently. We successfully loaded a dataset of one million patients for University of Kentucky (UK) Healthcare into DataSphere with more than 300 million clinical data records. We evaluated DataSphere by comparing it with an instance of i2b2 deployed at UK Healthcare, demonstrating that DataSphere provides enhanced user experience for both query building and execution. PMID:29854239

  10. SPHERES National Lab Facility

    NASA Technical Reports Server (NTRS)

    Benavides, Jose

    2014-01-01

    SPHERES is a facility of the ISS National Laboratory with three IVA nano-satellites designed and delivered by MIT to research estimation, control, and autonomy algorithms. Since Fall 2010, The SPHERES system is now operationally supported and managed by NASA Ames Research Center (ARC). A SPHERES Program Office was established and is located at NASA Ames Research Center. The SPHERES Program Office coordinates all SPHERES related research and STEM activities on-board the International Space Station (ISS), as well as, current and future payload development. By working aboard ISS under crew supervision, it provides a risk tolerant Test-bed Environment for Distributed Satellite Free-flying Control Algorithms. If anything goes wrong, reset and try again! NASA has made the capability available to other U.S. government agencies, schools, commercial companies and students to expand the pool of ideas for how to test and use these bowling ball-sized droids. For many of the researchers, SPHERES offers the only opportunity to do affordable on-orbit characterization of their technology in the microgravity environment. Future utilization of SPHERES as a facility will grow its capabilities as a platform for science, technology development, and education.

  11. Moving charged particles in lattice Boltzmann-based electrokinetics

    NASA Astrophysics Data System (ADS)

    Kuron, Michael; Rempfer, Georg; Schornbaum, Florian; Bauer, Martin; Godenschwager, Christian; Holm, Christian; de Graaf, Joost

    2016-12-01

    The motion of ionic solutes and charged particles under the influence of an electric field and the ensuing hydrodynamic flow of the underlying solvent is ubiquitous in aqueous colloidal suspensions. The physics of such systems is described by a coupled set of differential equations, along with boundary conditions, collectively referred to as the electrokinetic equations. Capuani et al. [J. Chem. Phys. 121, 973 (2004)] introduced a lattice-based method for solving this system of equations, which builds upon the lattice Boltzmann algorithm for the simulation of hydrodynamic flow and exploits computational locality. However, thus far, a description of how to incorporate moving boundary conditions into the Capuani scheme has been lacking. Moving boundary conditions are needed to simulate multiple arbitrarily moving colloids. In this paper, we detail how to introduce such a particle coupling scheme, based on an analogue to the moving boundary method for the pure lattice Boltzmann solver. The key ingredients in our method are mass and charge conservation for the solute species and a partial-volume smoothing of the solute fluxes to minimize discretization artifacts. We demonstrate our algorithm's effectiveness by simulating the electrophoresis of charged spheres in an external field; for a single sphere we compare to the equivalent electro-osmotic (co-moving) problem. Our method's efficiency and ease of implementation should prove beneficial to future simulations of the dynamics in a wide range of complex nanoscopic and colloidal systems that were previously inaccessible to lattice-based continuum algorithms.

  12. Radiation Budget Instrument (RBI) for JPSS-2

    NASA Technical Reports Server (NTRS)

    Georgieva, Elena; Priestley, Kory; Dunn, Barry; Cageao, Richard; Barki, Anum; Osmundsen, Jim; Turczynski, Craig; Abedin, Nurul

    2015-01-01

    Radiation Budget Instrument (RBI) will be one of five instruments flying aboard the JPSS-2 spacecraft, a polar-orbiting sun-synchronous satellite in Low Earth Orbit. RBI is a passive remote sensing instrument that will follow the successful legacy of the Clouds and Earth's Radiant Energy System (CERES) instruments to make measurement of Earth's short and longwave radiation budget. The goal of RBI is to provide an independent measurement of the broadband reflected solar radiance and Earth's emitted thermal radiance by using three spectral bands (Shortwave, Longwave, and Total) that will have the same overlapped point spread function (PSF) footprint on Earth. To ensure precise NIST-traceable calibration in space the RBI sensor is designed to use a visible calibration target (VCT), a solar calibration target (SCT), and an infrared calibration target (ICT) containing phase change cells (PCC) to enable on-board temperature calibration. The VCT is a thermally controlled integrating sphere with space grade Spectralon covering the inner surface. Two sides of the sphere will have fiber-coupled laser diodes in the UV to IR wavelength region. An electrical substitution radiometer on the integrating sphere will monitor the long term stability of the sources and the possible degradation of the Spectralon in space. In addition the radiometric calibration operations will use the Spectralon diffusers of the SCT to provide accurate measurements of Solar degradation. All those stable on-orbit references will ensure that calibration stability is maintained over the RBI sensor lifetime. For the preflight calibration the RBI will view five calibration sources - two integrating spheres and three CrIS (Cross-track Infrared Sounder ) -like blackbodies whose outputs will be validated with NIST calibration approach. Thermopile are the selected detectors for the RBI. The sensor has a requirement to perform lunar calibration in addition to solar calibration in space in a way similar to CERES instruments approach. To monitor climate change and to get stable and traceable results, it is critical to assure stable calibration over instrument lifetime.

  13. Curious case of gravitational lensing by binary black holes: A tale of two photon spheres, new relativistic images, and caustics

    NASA Astrophysics Data System (ADS)

    Patil, Mandar; Mishra, Priti; Narasimha, D.

    2017-01-01

    Binary black holes have been in the limelight of late due to the detection of gravitational waves from coalescing compact binaries in the events GW150914 and GW151226. In this paper we study gravitational lensing by the binary black holes modeled as an equal mass Majumdar-Papapetrou dihole metric and show that this system displays features that are quite unprecedented and absent in any other lensing configuration investigated so far in the literature. We restrict our attention to the light rays which move on the plane midway between the two identical black holes, which allows us to employ various techniques developed for the equatorial lensing in the spherically symmetric spacetimes. If distance between the two black holes is below a certain threshold value, then the system admits two photon spheres. As in the case of a single black hole, infinitely many relativistic images are formed due to the light rays which turn back from the region outside the outer (unstable) photon sphere, all of which lie beyond a critical angular radius with respect to the lens. However, in the presence of the inner (stable) photon sphere, the effective potential after admitting minimum turns upwards and blows up for the smaller values of radii and the light rays that enter the outer photon sphere can turn back, leading to the formation of a new set of infinitely many relativistic images, all of which lie below the critical radius from the lens mentioned above. As the distance between the two black holes is increased, two photon spheres approach one another, merge and eventually disappear. In the absence of the photon sphere, apart from the formation of a finite number of discrete relativistic images, the system remarkably admits a radial caustic, which has never been observed in the context of relativistic lensing before. Thus the system of the binary black hole admits novel features both in the presence and absence of photon spheres. We discuss possible observational signatures and implications of the binary black hole lensing.

  14. Exceptional arsenic (III,V) removal performance of highly porous, nanostructured ZrO2 spheres for fixed bed reactors and the full-scale system modeling.

    PubMed

    Cui, Hang; Su, Yu; Li, Qi; Gao, Shian; Shang, Jian Ku

    2013-10-15

    Highly porous, nanostructured zirconium oxide spheres were fabricated from ZrO2 nanoparticles with the assistance of agar powder to form spheres with size at millimeter level followed with a heat treatment at 450 °C to remove agar network, which provided a simple, low-cost, and safe process for the synthesis of ZrO2 spheres. These ZrO2 spheres had a dual-pore structure, in which interconnected macropores were beneficial for liquid transport and the mesopores could largely increase their surface area (about 98 m(2)/g) for effective contact with arsenic species in water. These ZrO2 spheres demonstrated an even better arsenic removal performance on both As(III) and As(V) than ZrO2 nanoparticles, and could be readily applied to commonly used fixed-bed adsorption reactors in the industry. A short bed adsorbent test was conducted to validate the calculated external mass transport coefficient and the pore diffusion coefficient. The performance of full-scale fixed bed systems with these ZrO2 spheres as the adsorber was estimated by the validated pore surface diffusion modeling. With the empty bed contact time (EBCT) at 10 min and the initial arsenic concentration at 30 ppb, the number of bed volumes that could be treated by these dry ZrO2 spheres reached ~255,000 BVs and ~271,000 BVs for As(III) and As(V), respectively, until the maximum contaminant level of 10 ppb was reached. These ZrO2 spheres are non-toxic, highly stable, and resistant to acid and alkali, have a high arsenic adsorption capacity, and could be easily adapted for various arsenic removal apparatus. Thus, these ZrO2 spheres may have a promising potential for their application in water treatment practice. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Development of paclitaxel-TyroSpheres for topical skin treatment

    PubMed Central

    Kilfoyle, Brian E.; Sheihet, Larisa; Zhang, Zheng; Laohoo, Marissa; Kohn, Joachim; Michniak-Kohn, Bozena B.

    2012-01-01

    A potential topical psoriasis therapy has been developed consisting of tyrosine-derived nanospheres (TyroSpheres) with encapsulated anti-proliferative paclitaxel. TyroSpheres provide enhancement of paclitaxel solubility (almost 4,000 times greater than PBS) by effective encapsulation and enable sustained, dose-controlled release over 72 hours under conditions mimicking skin permeation. TyroSpheres offer potential in the treatment of psoriasis, a disease resulting from over-proliferation of keratinocytes in the basal layer of the epidermis, by (a) enabling delivery of paclitaxel into the epidermis at concentrations >100 ng/cm2 of skin surface area and (b) enhancing the cytotoxicity of loaded paclitaxel to human keratinocytes (IC50 of paclitaxel-TyroSpheres was approximately 45% lower than that of free paclitaxel). TyroSpheres were incorporated into a gel-like viscous formulation to improve their flow characteristics with no impact on homogeneity, release or skin distribution of the payload. The findings reported here confirm that the TyroSpheres provide a platform for paclitaxel topical administration allowing skin drug localization and minimal systemic escape. PMID:22732474

  16. Rebound and jet formation of a fluid-filled sphere

    NASA Astrophysics Data System (ADS)

    Killian, Taylor W.; Klaus, Robert A.; Truscott, Tadd T.

    2012-12-01

    This study investigates the impact dynamics of hollow elastic spheres partially filled with fluid. Unlike an empty sphere, the internal fluid mitigates some of the rebound through an impulse driven exchange of energy wherein the fluid forms a jet inside the sphere. Surprisingly, this occurs on the second rebound or when the free surface is initially perturbed. Images gathered through experimentation show that the fluid reacts more quickly to the impact than the sphere, which decouples the two masses (fluid and sphere), imparts energy to the fluid, and removes rebound energy from the sphere. The experimental results are analyzed in terms of acceleration, momentum and an energy method suggesting an optimal fill volume in the neighborhood of 30%. While the characteristics of the fluid (i.e., density, viscosity, etc.) affect the fluid motion (i.e., type and size of jet formation), the rebound characteristics remain similar for a given fluid volume independent of fluid type. Implications of this work are a potential use of similar passive damping systems in sports technology and marine engineering.

  17. 3-D Printed Ultem 9085 Testing and Analysis

    NASA Technical Reports Server (NTRS)

    Aguilar, Daniel; Christensen, Sean; Fox, Emmet J.

    2015-01-01

    The purpose of this document is to analyze the mechanical properties of 3-D printed Ultem 9085. This document will focus on the capabilities, limitations, and complexities of 3D printing in general, and explain the methods by which this material is tested. Because 3-D printing is a relatively new process that offers an innovative means to produce hardware, it is important that the aerospace community understands its current advantages and limitations, so that future endeavors involving 3-D printing may be completely safe. This document encompasses three main sections: a Slosh damage assessment, a destructive test of 3-D printed Ultem 9085 samples, and a test to verify simulation for the 3-D printed SDP (SPHERES Docking Port). Described below, 'Slosh' and 'SDP' refer to two experiments that are built using Ultem 9085 for use with the SPHERES (Synchronized Position Hold, Engage, Reorient, Experimental Satellites) program onboard the International Space Station (ISS) [16]. The SPHERES Facility is managed out of the National Aeronautics and Space Administration (NASA) Ames Research Center in California.

  18. Thermodynamics of mixtures of patchy and spherical colloids of different sizes: A multi-body association theory with complete reference fluid information.

    PubMed

    Bansal, Artee; Valiya Parambathu, Arjun; Asthagiri, D; Cox, Kenneth R; Chapman, Walter G

    2017-04-28

    We present a theory to predict the structure and thermodynamics of mixtures of colloids of different diameters, building on our earlier work [A. Bansal et al., J. Chem. Phys. 145, 074904 (2016)] that considered mixtures with all particles constrained to have the same size. The patchy, solvent particles have short-range directional interactions, while the solute particles have short-range isotropic interactions. The hard-sphere mixture without any association site forms the reference fluid. An important ingredient within the multi-body association theory is the description of clustering of the reference solvent around the reference solute. Here we account for the physical, multi-body clusters of the reference solvent around the reference solute in terms of occupancy statistics in a defined observation volume. These occupancy probabilities are obtained from enhanced sampling simulations, but we also present statistical mechanical models to estimate these probabilities with limited simulation data. Relative to an approach that describes only up to three-body correlations in the reference, incorporating the complete reference information better predicts the bonding state and thermodynamics of the physical solute for a wide range of system conditions. Importantly, analysis of the residual chemical potential of the infinitely dilute solute from molecular simulation and theory shows that whereas the chemical potential is somewhat insensitive to the description of the structure of the reference fluid, the energetic and entropic contributions are not, with the results from the complete reference approach being in better agreement with particle simulations.

  19. Thermodynamics of mixtures of patchy and spherical colloids of different sizes: A multi-body association theory with complete reference fluid information

    NASA Astrophysics Data System (ADS)

    Bansal, Artee; Valiya Parambathu, Arjun; Asthagiri, D.; Cox, Kenneth R.; Chapman, Walter G.

    2017-04-01

    We present a theory to predict the structure and thermodynamics of mixtures of colloids of different diameters, building on our earlier work [A. Bansal et al., J. Chem. Phys. 145, 074904 (2016)] that considered mixtures with all particles constrained to have the same size. The patchy, solvent particles have short-range directional interactions, while the solute particles have short-range isotropic interactions. The hard-sphere mixture without any association site forms the reference fluid. An important ingredient within the multi-body association theory is the description of clustering of the reference solvent around the reference solute. Here we account for the physical, multi-body clusters of the reference solvent around the reference solute in terms of occupancy statistics in a defined observation volume. These occupancy probabilities are obtained from enhanced sampling simulations, but we also present statistical mechanical models to estimate these probabilities with limited simulation data. Relative to an approach that describes only up to three-body correlations in the reference, incorporating the complete reference information better predicts the bonding state and thermodynamics of the physical solute for a wide range of system conditions. Importantly, analysis of the residual chemical potential of the infinitely dilute solute from molecular simulation and theory shows that whereas the chemical potential is somewhat insensitive to the description of the structure of the reference fluid, the energetic and entropic contributions are not, with the results from the complete reference approach being in better agreement with particle simulations.

  20. Greenhouse Effect: Temperature of a Metal Sphere Surrounded by a Glass Shell and Heated by Sunlight

    ERIC Educational Resources Information Center

    Nguyen, Phuc H.; Matzner, Richard A.

    2012-01-01

    We study the greenhouse effect on a model satellite consisting of a tungsten sphere surrounded by a thin spherical, concentric glass shell, with a small gap between the sphere and the shell. The system sits in vacuum and is heated by sunlight incident along the "z"-axis. This development is a generalization of the simple treatment of the…

  1. A View of Developmental Education and the "Disadvantaged" in a National Perspective: Implications for International Education

    ERIC Educational Resources Information Center

    Wilson, Thomasyne Lightfoote

    1972-01-01

    After defining developmental education as referring to processes that expand the physical, emotional, educational, artistic, scientific, and political spheres of diverse ethnic and cultural communities within a nation, the author discusses the case of the Loma people of Liberia. (JM)

  2. Nucleation in Sheared Granular Matter

    NASA Astrophysics Data System (ADS)

    Rietz, Frank; Radin, Charles; Swinney, Harry L.; Schröter, Matthias

    2018-02-01

    We present an experiment on crystallization of packings of macroscopic granular spheres. This system is often considered to be a model for thermally driven atomic or colloidal systems. Cyclically shearing a packing of frictional spheres, we observe a first order phase transition from a disordered to an ordered state. The ordered state consists of crystallites of mixed fcc and hcp symmetry that coexist with the amorphous bulk. The transition, initiated by homogeneous nucleation, overcomes a barrier at 64.5% volume fraction. Nucleation consists predominantly of the dissolving of small nuclei and the growth of nuclei that have reached a critical size of about ten spheres.

  3. Casimir repulsion in sphere-plate geometry

    NASA Astrophysics Data System (ADS)

    Pirozhenko, Irina G.; Bordag, Michael

    2013-04-01

    The electromagnetic vacuum energy is considered in the presence of a perfectly conducting plane and a ball with dielectric permittivity ɛ and magnetic permeability μ, μ≠1. The attention is focused on the Casimir repulsion in this system caused by the magnetic permeability of the sphere. In the case of a perfectly permeable sphere, μ=∞, the vacuum energy is estimated numerically. The short- and long-distance asymptotes corresponding to the repulsive force and respective low-temperature corrections and high-temperature limits are found for a wide range of μ. The constraints on the Casimir repulsion in this system are discussed.

  4. Cluster analysis in systems of magnetic spheres and cubes

    NASA Astrophysics Data System (ADS)

    Pyanzina, E. S.; Gudkova, A. V.; Donaldson, J. G.; Kantorovich, S. S.

    2017-06-01

    In the present work we use molecular dynamics simulations and graph-theory based cluster analysis to compare self-assembly in systems of magnetic spheres, and cubes where the dipole moment is oriented along the side of the cube in the [001] crystallographic direction. We show that under the same conditions cubes aggregate far less than their spherical counterparts. This difference can be explained in terms of the volume of phase space in which the formation of the bond is thermodynamically advantageous. It follows that this volume is much larger for a dipolar sphere than for a dipolar cube.

  5. Remote Raman Efficiencies and Cross-Sections of Organic and Inorganic Chemicals.

    PubMed

    Acosta-Maeda, Tayro E; Misra, Anupam K; Porter, John N; Bates, David E; Sharma, Shiv K

    2017-05-01

    We determined Raman cross-sections of various organic liquids and inorganic polyatomic ions in aqueous solutions with a 532 nm pulsed laser using remote Raman systems developed at the University of Hawaii. Using a calibrated integrating sphere as a light source, we converted the intensity counts in the spectrum of the light from the integrating sphere measured with UH remote Raman instrument to spectral radiance. From these data, a response function of the remote Raman instrument was obtained. With the intensity-calibrated instrument, we collected remote Raman data from a standard 1 mm path length fused silica spectrophotometer cell filled with cyclohexane. The measured value of the differential Raman cross-section for the 801 cm -1 vibrational mode of cyclohexane is 4.55 × 10 -30 cm 2 sr -1 molecule -1 when excited by a 532 nm laser, in good agreement with the values reported in the literature. Using the measured cyclohexane Raman cross-section as a reference and relative Raman mode intensities of the various ions and organic liquids, we calculated the Raman cross-sections of the strongest Raman lines of nitrate, sulfate, carbonate, phosphate ions, and organic liquids by maintaining same experimental conditions for remote Raman detection. These relative Raman cross-section values will be useful for estimating detection capabilities of remote Raman systems for planetary exploration.

  6. Investigation of hydrodynamic characteristics of laminar flow condition around sphere using PIV system

    NASA Astrophysics Data System (ADS)

    Abed, A. H.; Shcheklein, S. E.

    2018-05-01

    This paper aims to determine the hydrodynamic characteristics of flow around the sphere in unsteady state condition. An experimental test-rig was designed and constructed for this purpose with the application of an adjusted laser optics system. It is based on the technology of pulsed particle visualization of micro tracers in the cross section per unit time interval. Visualization with Particle Image Velocimetry (PIV-system) is used to study the properties of the flow such as its structure. The PIV-system is the most accepted technique allowed one to measure the instantaneous velocity distribution in fluid applications. In this experimental study, o-ring is used to simulate turbulence on the sphere surface and creates very high-level fluctuations, which creates the flow undergoing a laminar-to-turbulent transition. This transition leads to a delay of the separation point of flow from the sphere surface causing a significant reduction in the drag coefficient, reaching 45%. New results obtained can be useful in the development of numerical validation as well as in design processes.

  7. SU-G-JeP4-05: Effects of Irregular Respiratory Motion On the Positioning Accuracy of Moving Target with Free Breathing Cone-Beam Computerized Tomography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, X; Xiong, W; Gewanter, R

    Purpose: Average or maximum intensity projection (AIP or MIP) images derived from 4DCT images are often used as a reference image for target alignment when free breathing Cone-beam CT (FBCBCT) is used for positioning a moving target at treatment. This method can be highly accurate if the patient has stable respiratory motion. However, a patient’s breathing pattern often varies irregularly. The purpose of this study is to investigate the effect of irregular respiration on the positioning accuracy of a moving target with FBCBCT. Methods: Eight patients’ respiratory motion curves were selected to drive a Quasar phantom with embedded cubic andmore » spherical targets. A 4DCT of the moving phantom was acquired on a CT scanner (Philips Brilliance 16) equipped with a Varian RPM system. The phase binned 4DCT images and the corresponding MIP and AIP images were transferred into Eclipse for analysis. CBCTs of the phantom driven by the same breathing curves were acquired on a Varian TrueBeam and fused such that the zero positions of moving targets are the same on both CBCT and AIP images. The sphere and cube volumes and centrioid differences (alignment error) determined by MIP, AIP and FBCBCT images were compared. Results: Compared to the volume determined by FBCBCT, the volumes of cube and sphere in MIP images were 22.4%±8.8% and 34.2%±6.2% larger while the volumes in AIP images were 7.1%±6.2% and 2.7%±15.3% larger, respectively. The alignment errors for the cube and sphere with center-center matches between MIP and FBCBCT were 3.5±3.1mm and 3.2±2.3mm, and the alignment errors between AIP and FBCBCT were 2.1±2.6mm and 2.1±1.7mm, respectively. Conclusion: AIP images appear to be superior reference images than MIP images. However, irregular respiratory motions could compromise the positioning accuracy of a moving target if the target center-center match is used to align FBCBCT and AIP images.« less

  8. SPHERES tethered formation flight testbed: application to NASA's SPECS mission

    NASA Astrophysics Data System (ADS)

    Chung, Soon-Jo; Kong, Edmund M.; Miller, David W.

    2005-08-01

    This paper elaborates on theory and experiment of the formation flight control for the future space-borne tethered interferometers. The nonlinear equations of multi-vehicle tethered spacecraft system are derived by Lagrange equations and decoupling method. The preliminary analysis predicts unstable dynamics depending on the direction of the tether motor. The controllability analysis indicates that both array resizing and spin-up are fully controllable only by the reaction wheels and the tether motor, thereby eliminating the need for thrusters. Linear and nonlinear decentralized control techniques have been implemented into the tethered SPHERES testbed, and tested at the NASA MSFC's flat floor facility using two and three SPHERES configurations. The nonlinear control using feedback linearization technique performed successfully in both two SPHERES in-line configuration and three triangular configuration while varying the tether length. The relative metrology system, using the ultra sound metrology system and the inertial sensors as well as the decentralized nonlinear estimator, is developed to provide necessary state information.

  9. [Children's health protection in the state political system].

    PubMed

    Baranov, A A; Iakovleva, T V; Lapin, Iu E

    2011-01-01

    The system of children's health protection in this country still lacks an adequate legal basis. Its improvement should be considered as a function of the state realized through legal regulation of public relations for the benefit of each child based on the legislatively fixed government policy in the sphere of children's health care. Such an approach may strengthen the role of this sphere in the intersectoral relations and implies the extension of pediatrics toward interaction with the spheres of politics and law. It reflects the understanding that physiological processes behind regulation of the functioning of the child's organism in the course of its development need an adequate support from the outside through regulation of public relations on behalf of children. The definition of state policy in the sphere of children's health care is proposed and its basic principles are considered.

  10. Communication: From close-packed to topologically close-packed: Formation of Laves phases in moderately polydisperse hard-sphere mixtures

    NASA Astrophysics Data System (ADS)

    Lindquist, Beth A.; Jadrich, Ryan B.; Truskett, Thomas M.

    2018-05-01

    Particle size polydispersity can help to inhibit crystallization of the hard-sphere fluid into close-packed structures at high packing fractions and thus is often employed to create model glass-forming systems. Nonetheless, it is known that hard-sphere mixtures with modest polydispersity still have ordered ground states. Here, we demonstrate by computer simulation that hard-sphere mixtures with increased polydispersity fractionate on the basis of particle size and a bimodal subpopulation favors the formation of topologically close-packed C14 and C15 Laves phases in coexistence with a disordered phase. The generality of this result is supported by simulations of hard-sphere mixtures with particle-size distributions of four different forms.

  11. Electronic transport properties of some liquid semiconductor

    NASA Astrophysics Data System (ADS)

    Sonvane, Y. A.; Thakor, P. B.; Jani, A. R.

    2012-06-01

    Electronic transport properties like electrical resistivity (ρ) and thermoelectric power (Q) of liquid semiconductor (Si, Ga, Ge, In, Sn, Tl and Bi) are calculated in the present study. Our well established single parametric model potential alongwith Percus Yevick hard sphere (PYHS) reference system are used to describe the structural information. To see the influence of exchange and correlation effect, Hartree, Taylor and Sarkar et al local field correlation functions are used. From present results, it is seen that good agreements between present results and experimental data have been achieved. Lastly we conclude that our model potential successfully produces the data of electronic transport properties for some liquid semiconductor (Si, Ga, Ge, In, Sn, Tl and Bi).

  12. Comparison of contact and non-contact asphere surface metrology devices

    NASA Astrophysics Data System (ADS)

    DeFisher, Scott; Fess, Edward M.

    2013-09-01

    Metrology of asphere surfaces is critical in the precision optics industry. Surface metrology serves as feedback into deterministic grinding and polishing platforms. Many different techniques and devices are used to qualify an asphere surface during fabrication. A contact profilometer is one of the most common measurement technologies used in asphere manufacturing. A profilometer uses a fine stylus to drag a diamond or ruby tip over the surface, resulting in a high resolution curved profile. Coordinate measuring machines (CMM) apply a similar concept by touching the optic with a ruby or silicon carbine sphere. A CMM is able to move in three dimensions while collecting data points along the asphere surface. Optical interferometers use a helium-neon laser with transmission spheres to compare a reflected wavefront from an asphere surface to a reference spherical wavefront. Large departure aspheres can be measured when a computer generated hologram (CGH) is introduced between the interferometer and the optic. OptiPro Systems has developed a non-contact CMM called UltraSurf. It utilizes a single point non-contact sensor, and high accuracy air bearings. Several different commercial non-contact sensors have been integrated, allowing for the flexibility to measure a variety of surfaces and materials. Metrology of a sphere and an asphere using a profilometer, CMM, Interferometer with a CGH, and the UltraSurf will be presented. Cross-correlation of the measured surface error magnitude and shape will be demonstrated. Comparisons between the techniques and devices will be also presented with attention to accuracy, repeatability, and overall measurement time.

  13. Macroscopic Floquet topological crystalline steel and superconductor pump

    NASA Astrophysics Data System (ADS)

    Rossi, Anna M. E. B.; Bugase, Jonas; Fischer, Thomas M.

    2017-08-01

    The transport of a macroscopic steel sphere and a superconducting sphere on top of two-dimensional periodic magnetic patterns is studied experimentally and compared with the theory and with experiments on topological transport of magnetic colloids. Transport of the steel and superconducting sphere is achieved by moving an external permanent magnet on a closed loop around the two-dimensional crystal. The transport is topological, i.e., the spheres are transported by a primitive unit vector of the lattice when the external magnet loop winds around specific directions. We experimentally determine the set of directions the loops must enclose for nontrivial transport of the spheres into various directions. We show that the loops can be used to sort steel and superconducting spheres. We show that the topological transport is robust with respect to the scale of the system and therefore speculate on its down scalability to the molecular scale.

  14. Demixing, surface nematization, and competing adsorption in binary mixtures of hard rods and hard spheres under confinement

    NASA Astrophysics Data System (ADS)

    Wu, Liang; Malijevský, Alexandr; Avendaño, Carlos; Müller, Erich A.; Jackson, George

    2018-04-01

    A molecular simulation study of binary mixtures of hard spherocylinders (HSCs) and hard spheres (HSs) confined between two structureless hard walls is presented. The principal aim of the work is to understand the effect of the presence of hard spheres on the entropically driven surface nematization of hard rod-like particles at surfaces. The mixtures are studied using a constant normal-pressure Monte Carlo algorithm. The surface adsorption at different compositions is examined in detail. At moderate hard-sphere concentrations, preferential adsorption of the spheres at the wall is found. However, at moderate to high pressure (density), we observe a crossover in the adsorption behavior with nematic layers of the rods forming at the walls leading to local demixing of the system. The presence of the spherical particles is seen to destabilize the surface nematization of the rods, and the degree of demixing increases on increasing the hard-sphere concentration.

  15. Central Configurations of the Curved N-Body Problem

    NASA Astrophysics Data System (ADS)

    Diacu, Florin; Stoica, Cristina; Zhu, Shuqiang

    2018-06-01

    We consider the N-body problem of celestial mechanics in spaces of nonzero constant curvature. Using the concept of effective potential, we define the moment of inertia for systems moving on spheres and hyperbolic spheres and show that we can recover the classical definition in the Euclidean case. After proving some criteria for the existence of relative equilibria, we find a natural way to define the concept of central configuration in curved spaces using the moment of inertia and show that our definition is formally similar to the one that governs the classical problem. We prove that, for any given point masses on spheres and hyperbolic spheres, central configurations always exist. We end with results concerning the number of central configurations that lie on the same geodesic, thus extending the celebrated theorem of Moulton to hyperbolic spheres and pointing out that it has no straightforward generalization to spheres, where the count gets complicated even for two bodies.

  16. Demixing, surface nematization, and competing adsorption in binary mixtures of hard rods and hard spheres under confinement.

    PubMed

    Wu, Liang; Malijevský, Alexandr; Avendaño, Carlos; Müller, Erich A; Jackson, George

    2018-04-28

    A molecular simulation study of binary mixtures of hard spherocylinders (HSCs) and hard spheres (HSs) confined between two structureless hard walls is presented. The principal aim of the work is to understand the effect of the presence of hard spheres on the entropically driven surface nematization of hard rod-like particles at surfaces. The mixtures are studied using a constant normal-pressure Monte Carlo algorithm. The surface adsorption at different compositions is examined in detail. At moderate hard-sphere concentrations, preferential adsorption of the spheres at the wall is found. However, at moderate to high pressure (density), we observe a crossover in the adsorption behavior with nematic layers of the rods forming at the walls leading to local demixing of the system. The presence of the spherical particles is seen to destabilize the surface nematization of the rods, and the degree of demixing increases on increasing the hard-sphere concentration.

  17. Broadband and wide-angle light harvesting by ultra-thin silicon solar cells with partially embedded dielectric spheres.

    PubMed

    Yang, Zhenhai; Shang, Aixue; Qin, Linling; Zhan, Yaohui; Zhang, Cheng; Gao, Pingqi; Ye, Jichun; Li, Xiaofeng

    2016-04-01

    We propose a design of crystalline silicon thin-film solar cells (c-Si TFSCs, 2 μm-thick) configured with partially embedded dielectric spheres on the light-injecting side. The intrinsic light trapping and photoconversion are simulated by the complete optoelectronic simulation. It shows that the embedding depth of the spheres provides an effective way to modulate and significantly enhance the optical absorption. Compared to the conventional planar and front sphere systems, the optimized partially embedded sphere design enables a broadband, wide-angle, and strong optical absorption and efficient carrier transportation. Optoelectronic simulation predicts that a 2 μm-thick c-Si TFSC with half-embedded spheres shows an increment of more than 10  mA/cm2 in short-circuit current density and an enhancement ratio of more than 56% in light-conversion efficiency, compared to the conventional planar counterparts.

  18. A reference-modified density functional theory: An application to solvation free-energy calculations for a Lennard-Jones solution.

    PubMed

    Sumi, Tomonari; Maruyama, Yutaka; Mitsutake, Ayori; Koga, Kenichiro

    2016-06-14

    In the conventional classical density functional theory (DFT) for simple fluids, an ideal gas is usually chosen as the reference system because there is a one-to-one correspondence between the external field and the density distribution function, and the exact intrinsic free-energy functional is available for the ideal gas. In this case, the second-order density functional Taylor series expansion of the excess intrinsic free-energy functional provides the hypernetted-chain (HNC) approximation. Recently, it has been shown that the HNC approximation significantly overestimates the solvation free energy (SFE) for an infinitely dilute Lennard-Jones (LJ) solution, especially when the solute particles are several times larger than the solvent particles [T. Miyata and J. Thapa, Chem. Phys. Lett. 604, 122 (2014)]. In the present study, we propose a reference-modified density functional theory as a systematic approach to improve the SFE functional as well as the pair distribution functions. The second-order density functional Taylor series expansion for the excess part of the intrinsic free-energy functional in which a hard-sphere fluid is introduced as the reference system instead of an ideal gas is applied to the LJ pure and infinitely dilute solution systems and is proved to remarkably improve the drawbacks of the HNC approximation. Furthermore, the third-order density functional expansion approximation in which a factorization approximation is applied to the triplet direct correlation function is examined for the LJ systems. We also show that the third-order contribution can yield further refinements for both the pair distribution function and the excess chemical potential for the pure LJ liquids.

  19. Design and analysis of optical systems for the Stanford/MSFC Multi-Spectral Solar Telescope Array

    NASA Astrophysics Data System (ADS)

    Hadaway, James B.; Johnson, R. Barry; Hoover, Richard B.; Lindblom, Joakim F.; Walker, Arthur B. C., Jr.

    1989-07-01

    This paper reports on the design and the theoretical ray trace analysis of the optical systems which will comprise the primary imaging components for the Stanford/MSFC Multi-Spectral Solar Telescope Array (MSSTA). This instrument is being developed for ultra-high resolution investigations of the sun from a sounding rocket. Doubly reflecting systems of sphere-sphere, ellipsoid-sphere (Dall-Kirkham), paraboloid-hyperboloid (Cassegrain), and hyperboloid-hyperboloid (Ritchey-Chretien) configurations were analyzed. For these mirror systems, ray trace analysis was performed and through-focus spot diagrams, point spread function plots, and geometrical and diffraction MTFs were generated. The results of these studies are presented along with the parameters of the Ritchey-Chretien optical system selected for the MSSTA flight. The payload, which incorporates seven of these Ritchey-Chretien systems, is now being prepared for launch in late September 1989.

  20. Design and analysis of optical systems for the Stanford/MSFC Multi-Spectral Solar Telescope Array

    NASA Technical Reports Server (NTRS)

    Hadaway, James B.; Johnson, R. Barry; Hoover, Richard B.; Lindblom, Joakim F.; Walker, Arthur B. C., Jr.

    1989-01-01

    This paper reports on the design and the theoretical ray trace analysis of the optical systems which will comprise the primary imaging components for the Stanford/MSFC Multi-Spectral Solar Telescope Array (MSSTA). This instrument is being developed for ultra-high resolution investigations of the sun from a sounding rocket. Doubly reflecting systems of sphere-sphere, ellipsoid-sphere (Dall-Kirkham), paraboloid-hyperboloid (Cassegrain), and hyperboloid-hyperboloid (Ritchey-Chretien) configurations were analyzed. For these mirror systems, ray trace analysis was performed and through-focus spot diagrams, point spread function plots, and geometrical and diffraction MTFs were generated. The results of these studies are presented along with the parameters of the Ritchey-Chretien optical system selected for the MSSTA flight. The payload, which incorporates seven of these Ritchey-Chretien systems, is now being prepared for launch in late September 1989.

  1. Potential Polymeric Sphere Construction Materials for a Spacecraft Electrostatic Shield

    NASA Technical Reports Server (NTRS)

    Smith, Joseph G., Jr.; Smith, Trent; Williams, Martha; Youngquist, Robert; Mendell, Wendell

    2006-01-01

    An electrostatic shielding concept for spacecraft radiation protection under NASA s Exploration Systems Research and Technology Program was evaluated for its effectiveness and feasibility. The proposed shield design is reminiscent of a classic quadrupole with positively and negatively charged spheres surrounding the spacecraft. The project addressed materials, shield configuration, power supply, and compared its effectiveness to that of a passive shield. The report herein concerns the identification of commercially available materials that could be used in sphere fabrication. It was found that several materials were needed to potentially construct the spheres for an electrostatic shield operating at 300 MV.

  2. Inclusion of Specialist and Generalist Stimuli in Attract-and-Kill Programs: Their Relative Efficacy in Apple Maggot Fly (Diptera: Tephritidae) Pest Management.

    PubMed

    Morrison, William R; Lee, Doo-Hyung; Reissig, W Harvey; Combs, David; Leahy, Kathleen; Tuttle, Arthur; Cooley, Daniel; Leskey, Tracy C

    2016-08-01

    Investigating the chemical ecology of agricultural systems continues to be a salient part of integrated pest management programs. Apple maggot fly, a key pest of apple in eastern North America, is a visual specialist with attraction to host fruit-mimicking cues. These cues have been incorporated into red spherical traps used for both monitoring and behaviorally based management. Incorporating generalist or specialist olfactory cues can potentially increase the overall success of this management system. The primary aim of this study was to evaluate the attractiveness of a generalist olfactory cue, ammonium carbonate, and the specialist olfactory cue, a five-component apple volatile blend, when included as a component of a red attracticidal sphere system. Secondly, we assessed how critical it was to maintain minimal deviation from the optimal, full-round specialist visual stimulus provided by red spheres. Finally, attracticidal spheres were deployed with specialist olfactory cues in commercial apple orchards to evaluate their potential for effective management of apple maggot. Ammonium carbonate did not increase residency, feeding time, or mortality in the laboratory-based trials. Field deployment of specialist olfactory cues increased apple maggot captures on red spheres, while the generalist cue did not. Apple maggot tolerated some deviation from the optimal visual stimulus without reducing captures on red spheres. Attracticidal spheres hung in perimeter trees in orchards resulted in acceptable and statistically identical levels of control compared with standard insecticide programs used by growers. Overall, our study contributes valuable information for developing a reliable attract-and-kill system for apple maggot. Published by Oxford University Press on behalf of Entomological Society of America 2016. This work is written by US Government employees and is in the public domain in the United States.

  3. Large-area photonic crystals

    NASA Astrophysics Data System (ADS)

    Ruhl, Tilmann; Spahn, Peter; Hellmann, Gotz P.; Winkler, Holger

    2004-09-01

    Materials with a periodically modulated refractive index, with periods on the scale of light wavelengths, are currently attracting much attention because of their unique optical properties which are caused by Bragg scattering of the visible light. In nature, 3d structures of this kind are found in the form of opals in which monodisperse silica spheres with submicron diameters form a face-centered-cubic (fcc) lattice. Artificial opals, with the same colloidal-crystalline fcc structure, have meanwhile been prepared by crystallizing spherical colloidal particles via sedimentation or drying of dispersions. In this report, colloidal crystalline films are introduced that were produced by a novel technique based on shear flow in the melts of specially designed submicroscopic silica-polymer core-shell hybrid spheres: when the melt of these spheres flows between the plates of a press, the spheres crystallize along the plates, layer by layer, and the silica cores assume the hexagonal order corresponding to the (111) plane of the fcc lattice. This process is fast and yields large-area films, thin or thick. To enhance the refractive index contrast in these films, the colloidal crystalline structure was inverted by etching out the silica cores with hydrofluoric acid. This type of an inverse opal, in which the fcc lattice is formed by mesopores, is referred to as a polymer-air photonic crystal.

  4. Adapting SAFT-γ perturbation theory to site-based molecular dynamics simulation. II. Confined fluids and vapor-liquid interfaces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ghobadi, Ahmadreza F.; Elliott, J. Richard, E-mail: elliot1@uakron.edu

    2014-07-14

    In this work, a new classical density functional theory is developed for group-contribution equations of state (EOS). Details of implementation are demonstrated for the recently-developed SAFT-γ WCA EOS and selective applications are studied for confined fluids and vapor-liquid interfaces. The acronym WCA (Weeks-Chandler-Andersen) refers to the characterization of the reference part of the third-order thermodynamic perturbation theory applied in formulating the EOS. SAFT-γ refers to the particular form of “statistical associating fluid theory” that is applied to the fused-sphere, heteronuclear, united-atom molecular models of interest. For the monomer term, the modified fundamental measure theory is extended to WCA-spheres. A newmore » chain functional is also introduced for fused and soft heteronuclear chains. The attractive interactions are taken into account by considering the structure of the fluid, thus elevating the theory beyond the mean field approximation. The fluctuations of energy are also included via a non-local third-order perturbation theory. The theory includes resolution of the density profiles of individual groups such as CH{sub 2} and CH{sub 3} and satisfies stoichiometric constraints for the density profiles. New molecular simulations are conducted to demonstrate the accuracy of each Helmholtz free energy contribution in reproducing the microstructure of inhomogeneous systems at the united-atom level of coarse graining. At each stage, comparisons are made to assess where the present theory stands relative to the current state of the art for studying inhomogeneous fluids. Overall, it is shown that the characteristic features of real molecular fluids are captured both qualitatively and quantitatively. For example, the average pore density deviates ∼2% from simulation data for attractive pentadecane in a 2-nm slit pore. Another example is the surface tension of ethane/heptane mixture, which deviates ∼1% from simulation data while the theory reproduces the excess accumulation of ethane at the interface.« less

  5. Perturbation theory for water with an associating reference fluid

    NASA Astrophysics Data System (ADS)

    Marshall, Bennett D.

    2017-11-01

    The theoretical description of the thermodynamics of water is challenged by the structural transition towards tetrahedral symmetry at ambient conditions. As perturbation theories typically assume a spherically symmetric reference fluid, they are incapable of accurately describing the liquid properties of water at ambient conditions. In this paper we address this problem by introducing the concept of an associated reference perturbation theory (APT). In APT we treat the reference fluid as an associating hard sphere fluid which transitions to tetrahedral symmetry in the fully hydrogen bonded limit. We calculate this transition in a theoretically self-consistent manner without appealing to molecular simulations. This associated reference provides the reference fluid for a second order Barker-Henderson perturbative treatment of the long-range attractions. We demonstrate that this approach gives a significantly improved description of water as compared to standard perturbation theories.

  6. Water based on a molecular model behaves like a hard-sphere solvent for a nonpolar solute when the reference interaction site model and related theories are employed

    NASA Astrophysics Data System (ADS)

    Hayashi, Tomohiko; Oshima, Hiraku; Harano, Yuichi; Kinoshita, Masahiro

    2016-09-01

    For neutral hard-sphere solutes, we compare the reduced density profile of water around a solute g(r), solvation free energy μ, energy U, and entropy S under the isochoric condition predicted by the two theories: dielectrically consistent reference interaction site model (DRISM) and angle-dependent integral equation (ADIE) theories. A molecular model for water pertinent to each theory is adopted. The hypernetted-chain (HNC) closure is employed in the ADIE theory, and the HNC and Kovalenko-Hirata (K-H) closures are tested in the DRISM theory. We also calculate g(r), U, S, and μ of the same solute in a hard-sphere solvent whose molecular diameter and number density are set at those of water, in which case the radial-symmetric integral equation (RSIE) theory is employed. The dependences of μ, U, and S on the excluded volume and solvent-accessible surface area are analyzed using the morphometric approach (MA). The results from the ADIE theory are in by far better agreement with those from computer simulations available for g(r), U, and μ. For the DRISM theory, g(r) in the vicinity of the solute is quite high and becomes progressively higher as the solute diameter d U increases. By contrast, for the ADIE theory, it is much lower and becomes further lower as d U increases. Due to unphysically positive U and significantly larger |S|, μ from the DRISM theory becomes too high. It is interesting that μ, U, and S from the K-H closure are worse than those from the HNC closure. Overall, the results from the DRISM theory with a molecular model for water are quite similar to those from the RSIE theory with the hard-sphere solvent. Based on the results of the MA analysis, we comparatively discuss the different theoretical methods for cases where they are applied to studies on the solvation of a protein.

  7. The Separate Spheres Model of Gendered Inequality.

    PubMed

    Miller, Andrea L; Borgida, Eugene

    2016-01-01

    Research on role congruity theory and descriptive and prescriptive stereotypes has established that when men and women violate gender stereotypes by crossing spheres, with women pursuing career success and men contributing to domestic labor, they face backlash and economic penalties. Less is known, however, about the types of individuals who are most likely to engage in these forms of discrimination and the types of situations in which this is most likely to occur. We propose that psychological research will benefit from supplementing existing research approaches with an individual differences model of support for separate spheres for men and women. This model allows psychologists to examine individual differences in support for separate spheres as they interact with situational and contextual forces. The separate spheres ideology (SSI) has existed as a cultural idea for many years but has not been operationalized or modeled in social psychology. The Separate Spheres Model presents the SSI as a new psychological construct characterized by individual differences and a motivated system-justifying function, operationalizes the ideology with a new scale measure, and models the ideology as a predictor of some important gendered outcomes in society. As a first step toward developing the Separate Spheres Model, we develop a new measure of individuals' endorsement of the SSI and demonstrate its reliability, convergent validity, and incremental predictive validity. We provide support for the novel hypotheses that the SSI predicts attitudes regarding workplace flexibility accommodations, income distribution within families between male and female partners, distribution of labor between work and family spheres, and discriminatory workplace behaviors. Finally, we provide experimental support for the hypothesis that the SSI is a motivated, system-justifying ideology.

  8. Synchronized Position Hold, Engage, Reorient, Experimental Satellites

    NASA Technical Reports Server (NTRS)

    Miller, David W.; Wilson, Edward; How, Jonathan; Sanenz-Otero, Alvar; Chamitoff, Gregory

    2009-01-01

    Synchronized Position Hold, Engage, Reorient, Experimental Satellites (SPHERES) are bowling-ball sized spherical satellites. They will be used inside the space station to test a set of well-defined instructions for spacecraft performing autonomous rendezvous and docking maneuvers. Three free-flying spheres will fly within the cabin of the station, performing flight formations. Each satellite is self-contained with power, propulsion, computers and navigation equipment. The results are important for satellite servicing, vehicle assembly and formation flying spacecraft configurations. SPHERES is a testbed for formation flying by satellites, the theories and calculations that coordinate the motion of multiple bodies maneuvering in microgravity. To achieve this inside the ISS cabin, bowling-ball-sized spheres perform various maneuvers (or protocols), with one to three spheres operating simultaneously . The Synchronized Position Hold, Engage, Reorient, Experimental Satellites (SPHERES) experiment will test relative attitude control and station-keeping between satellites, re-targeting and image plane filling maneuvers, collision avoidance and fuel balancing algorithms, and an array of geometry estimators used in various missions. SPHERES consists of three self-contained satellites, which are 18 sided polyhedrons that are 0.2 meter in diameter and weigh 3.5 kilograms. Each satellite contains an internal propulsion system, power, avionics, software, communications, and metrology subsystems. The propulsion system uses CO2, which is expelled through the thrusters. SPHERES satellites are powered by AA batteries. The metrology subsystem provides real-time position and attitude information. To simulate ground station-keeping, a laptop will be used to transmit navigational data and formation flying algorithms. Once these data are uploaded, the satellites will perform autonomously and hold the formation until a new command is given.

  9. The Separate Spheres Model of Gendered Inequality

    PubMed Central

    Miller, Andrea L.; Borgida, Eugene

    2016-01-01

    Research on role congruity theory and descriptive and prescriptive stereotypes has established that when men and women violate gender stereotypes by crossing spheres, with women pursuing career success and men contributing to domestic labor, they face backlash and economic penalties. Less is known, however, about the types of individuals who are most likely to engage in these forms of discrimination and the types of situations in which this is most likely to occur. We propose that psychological research will benefit from supplementing existing research approaches with an individual differences model of support for separate spheres for men and women. This model allows psychologists to examine individual differences in support for separate spheres as they interact with situational and contextual forces. The separate spheres ideology (SSI) has existed as a cultural idea for many years but has not been operationalized or modeled in social psychology. The Separate Spheres Model presents the SSI as a new psychological construct characterized by individual differences and a motivated system-justifying function, operationalizes the ideology with a new scale measure, and models the ideology as a predictor of some important gendered outcomes in society. As a first step toward developing the Separate Spheres Model, we develop a new measure of individuals’ endorsement of the SSI and demonstrate its reliability, convergent validity, and incremental predictive validity. We provide support for the novel hypotheses that the SSI predicts attitudes regarding workplace flexibility accommodations, income distribution within families between male and female partners, distribution of labor between work and family spheres, and discriminatory workplace behaviors. Finally, we provide experimental support for the hypothesis that the SSI is a motivated, system-justifying ideology. PMID:26800454

  10. Noncontact true temperature measurement. [of levitated sample using laser pyrometer

    NASA Technical Reports Server (NTRS)

    Lee, Mark C.; Allen, James L.

    1987-01-01

    A laser pyrometer has been developed for acquiring the true temperature of a levitated sample. The laser beam is first expanded to cover the entire cross-sectional surface of the target. For calibration of such a system, the reflectivity signal of an ideal 0.95 cm diameter gold-coated sphere (reflectivity = 0.99) is used as the reference for any other real targets. The emissivity of the real target can then be calculated. The overall system constant is obtained by passively measuring the radiance of a blackbody furnace (emissivity = 1.0) at a known, arbitrary temperature. Since the photo sensor used is highly linear over the entire operating temperature range, the true temperature of the target can then be computed. Preliminary results indicate that true temperatures thus obtained are in excellent correlation with thermocouple measured temperatures.

  11. Interface-coupled dissolution-precipitation processes allow a photonic crystal to replace an ionic crystal along lattice planes

    NASA Astrophysics Data System (ADS)

    Liesegang, Moritz; Milke, Ralf

    2015-04-01

    Nanocolloidal amorphous silica (SiO2×nH2O) is a major component of environmental aqueous solutions and surface coatings on rocks or mineral grains. Detailed knowledge of amorphous silica formation is indispensable for a better understanding of silicate rock alteration and diagenetic processes. We analyzed a wide range of samples from the Australian precious opal fields in South Australia and Queensland using petrographic microscopy, XRPD, SEM, and EPMA to characterize opaline silica, the mineral assemblage, and the host rock. Over the past 90 Ma the Lower Cretaceous lithologies of central Australia have undergone a weathering regime ranging from sub-tropical to arid, in which pH fluctuated from alkaline to acidic. The prolonged chemical alteration of sedimentary rocks derived from andesitic volcaniclastics and organic matter liberated large volumes of silica into solution, eventually leading to precipitation of nanocolloidal amorphous silica and formation of opal-A. A regular arrangement of close-packed uniform (monodisperse) spheres permits diffraction of white light and gives rise to the famous play-of-color. The opals in this study consist of silica spheres with an average diameter of 100-320 nm and often show a prominent core-shell structure. Two groups are separated by their relative standard deviation (RSD): monodisperse spheres (RSD<6%) and polydisperse spheres (RDS>10%). Monodisperse and polydisperse spheres are separated by their Na/K ratio, restricting the appearance of monodisperse spheres to values <1.2 and polydisperse spheres to values >3.0. We suggest that the Na/K ratio represents significant differences in the overall solution characteristics. The associated minerals (e.g., alunite, gypsum, kaolinite, K feldspar) indicate large variations of fluid composition and pH. Probably, uniform spheres grew at acidic pH, with repulsive forces large enough to arrange them in an ordered array prior to the evaporation of interstitial fluids. The investigation of fossil shells replaced by opal-A reveals clues for the understanding of structural and chemical reorganization mechanisms behind silica pseudomorphism. Fundamental knowledge about the highly selective replacement process is absent so far, impeding an adequate interpretation of the observations. The replacement of calcitic shells by amorphous silica spheres (~300 nm in size) is a unique example for the transformation of an ionic to a photonic crystal accompanied by a large size contrast of ions and spheres, respectively, but preserving lattice planes. The observed replication of polysynthetic twinning and cleavage planes of calcite by opal-A spheres indicates that silicification occurs via dissolution of shell material and immediate precipitation of amorphous silica. This follows the interface-coupled dissolution-precipitation mechanism model (Putnis and Putnis, 2007), but requires some modification to allow for open space necessary to form spheres in the 100s-nm size range with a core-shell structure. While sphere growth by a gravitational ordering process is implausible, we assume that the ordered array of monodisperse spheres forms via layer-by-layer deposition. References: Putnis A. and Putnis C.V. (2007), J. Solid State Chem., 180, 1783-1786

  12. Size-dependent scanning parameters (kVp and mAs) for photon-counting spectral CT system in pediatric imaging: simulation study

    NASA Astrophysics Data System (ADS)

    Chen, Han; Danielsson, Mats; Xu, Cheng

    2016-06-01

    We are developing a photon-counting spectral CT detector with a small pixel size of 0.4× 0.5 mm2, offering a potential advantage for better visualization of small structures in pediatric patients. The purpose of this study is to determine the patient size dependent scanning parameters (kVp and mAs) for pediatric CT in two imaging cases: adipose imaging and iodinated blood imaging. Cylindrical soft-tissue phantoms of diameters between 10-25 cm were used to mimic patients of different ages from 0 to 15 y. For adipose imaging, a 5 mm diameter adipose sphere was assumed as an imaging target, while in the case of iodinated imaging, an iodinated blood sphere of 1 mm in diameter was assumed. By applying the geometry of a commercial CT scanner (GE Lightspeed VCT), simulations were carried out to calculate the detectability index, {{d}\\prime 2} , with tube potentials varying from 40 to 140 kVp. The optimal kVp for each phantom in each imaging case was determined such that the dose-normalized detectability index, {{d}\\prime 2}/ dose, is maximized. With the assumption that the detectability index in pediatric imaging is required the same as in typical adult imaging, the value of mAs at optimal kVp for each phantom was selected to achieve a reference detectability index that was obtained by scanning an adult phantom (30 cm in diameter) in a typical adult CT procedure (120 kVp and 200 mAs) using a modeled energy-integrating system. For adipose imaging, the optimal kVps are 50, 60, 80, and 120 kVp, respectively, for phantoms of 10, 15, 20, and 25 cm in diameter. The corresponding mAs values required to achieve the reference detectability index are only 9%, 23%, 24%, and 54% of the mAs that is used for adult patients at 120 kVp, for 10, 15, 20, and 25 cm diameter phantoms, respectively. In the case of iodinated imaging, a tube potential of 60 kVp was found optimal for all phantoms investigated, and the mAs values required to achieve the reference detectability index are 2%, 9%, 37%, and 109% of the adult mAs. The results also indicate that with the use of respective optimal kVps, the photon-counting spectral system offers up to 30% higher {{d}\\prime 2}/ dose than the modeled energy-integrating system for adipose imaging, and 70% for iodinated imaging.

  13. Pushing the glass transition towards random close packing using self-propelled hard spheres

    NASA Astrophysics Data System (ADS)

    Ni, Ran; Stuart, Martien A. Cohen; Dijkstra, Marjolein

    2013-10-01

    Although the concept of random close packing with an almost universal packing fraction of approximately 0.64 for hard spheres was introduced more than half a century ago, there are still ongoing debates. The main difficulty in searching the densest packing is that states with packing fractions beyond the glass transition at approximately 0.58 are inherently non-equilibrium systems, where the dynamics slows down with a structural relaxation time diverging with density; hence, the random close packing is inaccessible. Here we perform simulations of self-propelled hard spheres, and we find that with increasing activity the relaxation dynamics can be sped up by orders of magnitude. The glass transition shifts to higher packing fractions upon increasing the activity, allowing the study of sphere packings with fluid-like dynamics at packing fractions close to RCP. Our study opens new possibilities of investigating dense packings and the glass transition in systems of hard particles.

  14. SPHERES tethered formation flight testbed: advancements in enabling NASA's SPECS mission

    NASA Astrophysics Data System (ADS)

    Chung, Soon-Jo; Adams, Danielle; Saenz-Otero, Alvar; Kong, Edmund; Miller, David W.; Leisawitz, David; Lorenzini, Enrico; Sell, Steve

    2006-06-01

    This paper reports on efforts to control a tethered formation flight spacecraft array for NASA's SPECS mission using the SPHERES test-bed developed by the MIT Space Systems Laboratory. Specifically, advances in methodology and experimental results realized since the 2005 SPIE paper are emphasized. These include a new test-bed setup with a reaction wheel assembly, a novel relative attitude measurement system using force torque sensors, and modeling of non-ideal tethers to account for tether vibration modes. The nonlinear equations of motion of multi-vehicle tethered spacecraft with elastic flexible tethers are derived from Lagrange's equations. The controllability analysis indicates that both array resizing and spin-up are fully controllable by the reaction wheels and the tether motor, thereby saving thruster fuel consumption. Based upon this analysis, linear and nonlinear controllers have been successfully implemented on the tethered SPHERES testbed, and tested at the NASA MSFC's flat floor facility using two and three SPHERES configurations.

  15. Drag-Free Control and Drag Force Recovery of Small Satellites

    NASA Technical Reports Server (NTRS)

    Nguyen, Anh N.; Conklin, John W.

    2017-01-01

    Drag-free satellites provide autonomous precision orbit determination, accurately map the static and time varying components of Earth's mass distribution, aid in our understanding of the fundamental force of gravity, and will ultimately open up a new window to our universe through the detection and observation of gravitational waves. At the heart of this technology is a gravitational reference sensor, which (a) contains and shields a free-floating proof mass from all non-gravitational forces, and (b) precisely measures the position of the test mass inside the sensor. Thus, both test mass and spacecraft follow a pure geodesic in spacetime. By tracking the position of a low Earth orbiting drag-free satellite we can directly determine the detailed shape of geodesics and through analysis, the higher order harmonics of the Earths geopotential. This paper explores two different drag-free control systems on small satellites. The first drag-free control system is a continuously compensated single thruster 3-unit CubeSat with a suspension-free spherical proof-mass. A feedback control system commands the thruster and Attitude and Determination Control System to fly the tender spacecraft with respect to the test mass. The spheres position is sensed with a LED-based differential optical shadow sensor, its electric charge controlled by photoemission using UV LEDs, and the spacecraft position is maintained with respect to the sphere using an ion electrospray propulsion system. This configuration is the most fuel-efficient drag-free system possible today. The second drag-free control system is an electro-statically suspended cubical proof-mass that is operated with a low duty cycle, limiting suspension force noise over brief, known time intervals on a small GRACE-II -like satellite. The readout is performed using a laser interferometer, which is immune to the dynamic range limitations of voltage references. This system eliminates the need for a thruster, enabling drag-free control systems for passive satellites. In both cases, the test mass position, GPS tracking data, and commanded actuation, either thrust or suspension system, can be analyzed to estimate the 3-axis drag forces acting on the satellite. The data produces the most precise maps of upper atmospheric drag forces and with additional information, detailed models that describe the dynamics of the upper atmosphere and its impact on all satellites that orbit the Earth. This paper highlights the history, applications, design, laboratory technology development and highly detailed simulation results of each control system.

  16. Spherical D-brane by tachyon condensation

    NASA Astrophysics Data System (ADS)

    Asakawa, Tsuguhiko; Matsuura, So

    2018-03-01

    We find a novel tachyon condensation which provides a D-brane system with spherical worldvolume in the flat spacetime. The tachyon profile is a deformation of a known D0-brane solution on non-BPS D3-branes in type IIA superstring theory, which realizes a bound state of a spherical D2-brane and a D0-brane. The D0-brane is resolved into the sphere as a U(1) monopole flux of the unit magnetic charge. We show that the system has the correct tension and the RR-coupling. Although the low-energy effective action of the system is the same as that of the dual description of the fuzzy sphere solution of multiple D0-branes, our system cannot be equivalent to the fuzzy sphere. The use of projective modules in describing the tachyon condensation is emphasized.

  17. Resource letter ETC-1 - Extraterrestrial civilization

    NASA Technical Reports Server (NTRS)

    Kuiper, Thomas B. H.; Brin, Glen David

    1989-01-01

    This resource letter provides a guide to the literature about intelligent life beyond the human sphere of exploration. It offers a starting point for professionals and academics interested in participating in the debate about the existence of other technological civilizations or in SETI. It can also serve as a reference for teaching. Several extensive bibliographies are cited.

  18. The Common Core: Far from Home

    ERIC Educational Resources Information Center

    Toscano, Michael

    2013-01-01

    In this opinion piece, Michael Toscano writes that his criticism of the Common Core State Standards ultimately has very little to do with their innate quality, but rather that their relation to other social spheres is disordered. He refers to the full reordering of American education away from families and local communities--which he states are…

  19. Navigating the Information Revolution: Choices for Laggard Countries

    ERIC Educational Resources Information Center

    Gatune, Julius

    2007-01-01

    The rapid diffusion of information and communication technologies (ICTs) during the last two decades has had a profound impact on all spheres of human endeavors, changes that are collectively referred to as the Information Revolution (IR). But the revolution has been uneven, with some countries being far ahead and others far behind in IR,…

  20. The Grand Challenges Discourse: Transforming Identity Work in Science and Science Policy.

    PubMed

    Kaldewey, David

    2018-01-01

    This article analyzes the concept of "grand challenges" as part of a shift in how scientists and policymakers frame and communicate their respective agendas. The history of the grand challenges discourse helps to understand how identity work in science and science policy has been transformed in recent decades. Furthermore, the question is raised whether this discourse is only an indicator, or also a factor in this transformation. Building on conceptual history and historical semantics, the two parts of the article reconstruct two discursive shifts. First, the observation that in scientific communication references to "problems" are increasingly substituted by references to "challenges" indicates a broader cultural trend of how attitudes towards what is problematic have shifted in the last decades. Second, as the grand challenges discourse is rooted in the sphere of sports and competition, it introduces a specific new set of societal values and practices into the spheres of science and technology. The article concludes that this process can be characterized as the sportification of science, which contributes to self-mobilization and, ultimately, to self-optimization of the participating scientists, engineers, and policymakers.

  1. Excess Entropy Scaling Law for Diffusivity in Liquid Metals

    PubMed Central

    Jakse, N.; Pasturel, A.

    2016-01-01

    Understanding how dynamic properties depend on the structure and thermodynamics in liquids is a long-standing open problem in condensed matter physics. A very simple approach is based on the Dzugutov contribution developed on model fluids in which a universal (i.e. species-independent) connection relates the pair excess entropy of a liquid to its reduced diffusion coefficient. However its application to “real” liquids still remains uncertain due to the ability of a hard sphere (HS) reference fluid used in reducing parameters to describe complex interactions that occur in these liquids. Here we use ab initio molecular dynamics simulations to calculate both structural and dynamic properties at different temperatures for a wide series of liquid metals including Al, Au, Cu, Li, Ni, Ta, Ti, Zn as well as liquid Si and B. From this analysis, we demonstrate that the Dzugutov scheme can be applied successfully if a self-consistent method to determine the packing fraction of the hard sphere reference fluid is used as well as the Carnahan-Starling approach to express the excess entropy. PMID:26862002

  2. Results of Second Outdoor Comparison Between Absolute Cavity Pyrgeometer (ACP) and Infrared Integrating Sphere (IRIS) Radiometer at PMOD (Presentation)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reda, I.; Grobner, J.; Wacker, S.

    The Absolute Cavity Pyrgeometer (ACP) and InfraRed Integrating Sphere radiometer (IRIS) are developed to establish a world reference for calibrating pyrgeometers with traceability to SI units. The two radiometers are un-windowed with negligible spectral dependence, and traceable to SI units through the temperature scale (ITS-90). The second outdoor comparison between the two designs was held from September 30 to October 11, 2013 at the Physikalisch-Metorologisches Observatorium Davos (PMOD). The difference between the irradiance measured by ACP and that of the IRIS was within 1 W/m2 (3 IRISs: PMOD + Australia + Germany). From the first and second comparisons, a differencemore » of 4-6 W/m2 was observed between the irradiance measured by ACP&IRIS and that of the interim World Infrared Standard Group (WISG). This presentation includes results from the first and second comparison in an effort to establish the world reference for pyrgeometer calibrations, a key deliverable for the World Meteorological Organization (WMO), and the DOE-ASR.« less

  3. Quantum efficiency measurement of the Transiting Exoplanet Survey Satellite (TESS) CCD detectors

    NASA Astrophysics Data System (ADS)

    Krishnamurthy, A.; Villasenor, J.; Thayer, C.; Kissel, S.; Ricker, G.; Seager, S.; Lyle, R.; Deline, A.; Morgan, E.; Sauerwein, T.; Vanderspek, R.

    2016-07-01

    Very precise on-ground characterization and calibration of TESS CCD detectors will significantly assist in the analysis of the science data from the mission. An accurate optical test bench with very high photometric stability has been developed to perform precise measurements of the absolute quantum efficiency. The setup consists of a vacuum dewar with a single MIT Lincoln Lab CCID-80 device mounted on a cold plate with the calibrated reference photodiode mounted next to the CCD. A very stable laser-driven light source is integrated with a closed-loop intensity stabilization unit to control variations of the light source down to a few parts-per-million when averaged over 60 s. Light from the stabilization unit enters a 20 inch integrating sphere. The output light from the sphere produces near-uniform illumination on the cold CCD and on the calibrated reference photodiode inside the dewar. The ratio of the CCD and photodiode signals provides the absolute quantum efficiency measurement. The design, key features, error analysis, and results from the test campaign are presented.

  4. How to make thermodynamic perturbation theory to be suitable for low temperature?

    NASA Astrophysics Data System (ADS)

    Zhou, Shiqi

    2009-02-01

    Low temperature unsuitability is a problem plaguing thermodynamic perturbation theory (TPT) for years. Present investigation indicates that the low temperature predicament can be overcome by employing as reference system a nonhard sphere potential which incorporates one part of the attractive ingredient in a potential function of interest. In combination with a recently proposed TPT [S. Zhou, J. Chem. Phys. 125, 144518 (2006)] based on a λ expansion (λ being coupling parameter), the new perturbation strategy is employed to predict for several model potentials. It is shown that the new perturbation strategy can very accurately predict various thermodynamic properties even if the potential range is extremely short and hence the temperature of interest is very low and current theoretical formalisms seriously deteriorate or critically fail to predict even the existence of the critical point. Extensive comparison with existing liquid state theories and available computer simulation data discloses a superiority of the present TPT to two Ornstein-Zernike-type integral equation theories, i.e., hierarchical reference theory and self-consistent Ornstein-Zernike approximation.

  5. How to make thermodynamic perturbation theory to be suitable for low temperature?

    PubMed

    Zhou, Shiqi

    2009-02-07

    Low temperature unsuitability is a problem plaguing thermodynamic perturbation theory (TPT) for years. Present investigation indicates that the low temperature predicament can be overcome by employing as reference system a nonhard sphere potential which incorporates one part of the attractive ingredient in a potential function of interest. In combination with a recently proposed TPT [S. Zhou, J. Chem. Phys. 125, 144518 (2006)] based on a lambda expansion (lambda being coupling parameter), the new perturbation strategy is employed to predict for several model potentials. It is shown that the new perturbation strategy can very accurately predict various thermodynamic properties even if the potential range is extremely short and hence the temperature of interest is very low and current theoretical formalisms seriously deteriorate or critically fail to predict even the existence of the critical point. Extensive comparison with existing liquid state theories and available computer simulation data discloses a superiority of the present TPT to two Ornstein-Zernike-type integral equation theories, i.e., hierarchical reference theory and self-consistent Ornstein-Zernike approximation.

  6. Elisabeth Kubler-Ross and the Tradition of the Private Sphere: An Analysis of Symbols.

    ERIC Educational Resources Information Center

    Klass, Dennis

    1981-01-01

    Shows how Kubler-Ross' schema functions as a symbol system. Analyzes the symbol "acceptance." Shows how that symbol is part of a strong American tradition of symbols of the private sphere. (Author/JAC)

  7. Spectrophotometer-Integrating-Sphere System for Computing Solar Absorptance

    NASA Technical Reports Server (NTRS)

    Witte, William G., Jr.; Slemp, Wayne S.; Perry, John E., Jr.

    1991-01-01

    A commercially available ultraviolet, visible, near-infrared spectrophotometer was modified to utilize an 8-inch-diameter modified Edwards-type integrated sphere. Software was written so that the reflectance spectra could be used to obtain solar absorptance values of 1-inch-diameter specimens. A descriptions of the system, spectral reflectance, and software for calculation of solar absorptance from reflectance data are presented.

  8. Model-based sphere localization (MBSL) in x-ray projections

    NASA Astrophysics Data System (ADS)

    Sawall, Stefan; Maier, Joscha; Leinweber, Carsten; Funck, Carsten; Kuntz, Jan; Kachelrieß, Marc

    2017-08-01

    The detection of spherical markers in x-ray projections is an important task in a variety of applications, e.g. geometric calibration and detector distortion correction. Therein, the projection of the sphere center on the detector is of particular interest as the used spherical beads are no ideal point-like objects. Only few methods have been proposed to estimate this respective position on the detector with sufficient accuracy and surrogate positions, e.g. the center of gravity, are used, impairing the results of subsequent algorithms. We propose to estimate the projection of the sphere center on the detector using a simulation-based method matching an artificial projection to the actual measurement. The proposed algorithm intrinsically corrects for all polychromatic effects included in the measurement and absent in the simulation by a polynomial which is estimated simultaneously. Furthermore, neither the acquisition geometry nor any object properties besides the fact that the object is of spherical shape need to be known to find the center of the bead. It is shown by simulations that the algorithm estimates the center projection with an error of less than 1% of the detector pixel size in case of realistic noise levels and that the method is robust to the sphere material, sphere size, and acquisition parameters. A comparison to three reference methods using simulations and measurements indicates that the proposed method is an order of magnitude more accurate compared to these algorithms. The proposed method is an accurate algorithm to estimate the center of spherical markers in CT projections in the presence of polychromatic effects and noise.

  9. Exact evaluation of the depletion force between nanospheres in a polydisperse polymer fluid under Θ conditions.

    PubMed

    Wang, Haiqiang; Woodward, Clifford E; Forsman, Jan

    2014-05-21

    We analyze a system consisting of two spherical particles immersed in a polydispersed polymer solution under theta conditions. An exact theory is developed to describe the potential of mean force between the spheres for the case where the polymer molecular weight dispersity is described by the Schulz-Flory distribution. Exact results can be derived for the protein regime, where the sphere radius (R(s)) is small compared to the average radius of gyration of the polymer (R(g)). Numerical results are relatively easily obtained in the cases where the sphere radius is increased. We find that even when q = R(g)/R(s) ⪆ 10, then the use of a monopole expansion for the polymer end-point distribution about the spheres is sufficient. For even larger spheres q ≈ 1, accuracy is maintained by including a dipolar correction. The implications of these findings on generating a full many-body effective interaction for a collection of N spheres imbedded in the polymer solution are discussed.

  10. Optimum radars and filters for the passive sphere system

    NASA Technical Reports Server (NTRS)

    Luers, J. K.; Soltes, A.

    1971-01-01

    Studies have been conducted to determine the influence of the tracking radar and data reduction technique on the accuracy of the meteorological measurements made in the 30 to 100 kilometer altitude region by the ROBIN passive falling sphere. A survey of accuracy requirements was made of agencies interested in data from this region of the atmosphere. In light of these requirements, various types of radars were evaluated to determine the tracking system most applicable to the ROBIN, and methods were developed to compute the errors in wind and density that arise from noise errors in the radar supplied data. The effects of launch conditions on the measurements were also examined. Conclusions and recommendations have been made concerning the optimum tracking and data reduction techniques for the ROBIN falling sphere system.

  11. Intra prediction using face continuity in 360-degree video coding

    NASA Astrophysics Data System (ADS)

    Hanhart, Philippe; He, Yuwen; Ye, Yan

    2017-09-01

    This paper presents a new reference sample derivation method for intra prediction in 360-degree video coding. Unlike the conventional reference sample derivation method for 2D video coding, which uses the samples located directly above and on the left of the current block, the proposed method considers the spherical nature of 360-degree video when deriving reference samples located outside the current face to which the block belongs, and derives reference samples that are geometric neighbors on the sphere. The proposed reference sample derivation method was implemented in the Joint Exploration Model 3.0 (JEM-3.0) for the cubemap projection format. Simulation results for the all intra configuration show that, when compared with the conventional reference sample derivation method, the proposed method gives, on average, luma BD-rate reduction of 0.3% in terms of the weighted spherical PSNR (WS-PSNR) and spherical PSNR (SPSNR) metrics.

  12. From square-well to Janus: Improved algorithm for integral equation theory and comparison with thermodynamic perturbation theory within the Kern-Frenkel model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Giacometti, Achille, E-mail: achille.giacometti@unive.it; Gögelein, Christoph, E-mail: christoph.goegelein@ds.mpg.de; Lado, Fred, E-mail: lado@ncsu.edu

    2014-03-07

    Building upon past work on the phase diagram of Janus fluids [F. Sciortino, A. Giacometti, and G. Pastore, Phys. Rev. Lett. 103, 237801 (2009)], we perform a detailed study of integral equation theory of the Kern-Frenkel potential with coverage that is tuned from the isotropic square-well fluid to the Janus limit. An improved algorithm for the reference hypernetted-chain (RHNC) equation for this problem is implemented that significantly extends the range of applicability of RHNC. Results for both structure and thermodynamics are presented and compared with numerical simulations. Unlike previous attempts, this algorithm is shown to be stable down to themore » Janus limit, thus paving the way for analyzing the frustration mechanism characteristic of the gas-liquid transition in the Janus system. The results are also compared with Barker-Henderson thermodynamic perturbation theory on the same model. We then discuss the pros and cons of both approaches within a unified treatment. On balance, RHNC integral equation theory, even with an isotropic hard-sphere reference system, is found to be a good compromise between accuracy of the results, computational effort, and uniform quality to tackle self-assembly processes in patchy colloids of complex nature. Further improvement in RHNC however clearly requires an anisotropic reference bridge function.« less

  13. Development of traceable measurement of the diffuse optical properties of solid reference standards for biomedical optics at National Institute of Standards and Technology.

    PubMed

    Lemaillet, Paul; Bouchard, Jean-Pierre; Allen, David W

    2015-07-01

    The development of a national reference instrument dedicated to the measurement of the scattering and absorption properties of solid tissue-mimicking phantoms used as reference standards is presented. The optical properties of the phantoms are measured with a double-integrating sphere setup in the steady-state domain, coupled with an inversion routine of the adding-doubling procedure that allows for the computation of the uncertainty budget for the measurements. The results are compared to the phantom manufacturer's values obtained by a time-resolved approach. The results suggest that the agreement between these two independent methods is within the estimated uncertainties. This new reference instrument will provide optical biomedical research laboratories with reference values for absolute diffuse optical properties of phantom materials.

  14. Minimal two-sphere model of the generation of fluid flow at low Reynolds numbers.

    PubMed

    Leoni, M; Bassetti, B; Kotar, J; Cicuta, P; Cosentino Lagomarsino, M

    2010-03-01

    Locomotion and generation of flow at low Reynolds number are subject to severe limitations due to the irrelevance of inertia: the "scallop theorem" requires that the system have at least two degrees of freedom, which move in non-reciprocal fashion, i.e. breaking time-reversal symmetry. We show here that a minimal model consisting of just two spheres driven by harmonic potentials is capable of generating flow. In this pump system the two degrees of freedom are the mean and relative positions of the two spheres. We have performed and compared analytical predictions, numerical simulation and experiments, showing that a time-reversible drive is sufficient to induce flow.

  15. Theoretical Investigation of Phonon Dispersion Relation of 3d Liquid Transition Metals

    NASA Astrophysics Data System (ADS)

    Thakor, P. B.; Sonvane, Y. A.; Gajjar, P. N.; Jani, A. R.

    2011-12-01

    The phonon dispersion relations of 3d liquid transition metals have been obtained in the present study. We have used Hubbard and Beeby (HB) method to generate phonon dispersion relation of liquid metals. To describe the structural information, the structure factor S(q) due to the Percus-Yevick hard sphere (PYHS) reference systems is used along with our newly constructed parameter free model potential. The influence of exchange and correlation effect on the phonon dispersion relation of 3d liquid transition metals is examined explicitly, which reflects the varying effects of screening. We have used different local field correction functions like Hartree (H), Taylor (T) and Sarkar et al (S). Present results have found good in agreement with available experimental data.

  16. Mechanical properties of 4d transition metals in molten state

    NASA Astrophysics Data System (ADS)

    Singh, Deobrat; Sonvane, Yogesh; Thakor, P. B.

    2016-05-01

    Mechanical properties of 4d transition metals in molten state have been studied in the present study. We have calculated mechanical properties such as isothermal bulk modulus (B), modulus of rigidity (G), Young's modulus (Y) and Hardness have also been calculated from the elastic part of the Phonon dispersion curve (PDC). To describe the structural information, we have used different structure factor S(q) using Percus-Yevick hard sphere (PYHS) reference systems along with our newly constructed parameter free model potential.To see the influence of exchange and correlation effect on the above said properties of 3d liquid transition metals, we have used Sarkar et al (S)local field correction functions. Present results have been found good in agreement with available experimental data.

  17. NOAA's Science On a Sphere Education Program: Application of a Scientific Visualization System to Teach Earth System Science and Improve our Understanding About Creating Effective Visualizations

    NASA Astrophysics Data System (ADS)

    McDougall, C.; McLaughlin, J.

    2008-12-01

    NOAA has developed several programs aimed at facilitating the use of earth system science data and data visualizations by formal and informal educators. One of them, Science On a Sphere, a visualization display tool and system that uses networked LCD projectors to display animated global datasets onto the outside of a suspended, 1.7-meter diameter opaque sphere, enables science centers, museums, and universities to display real-time and current earth system science data. NOAA's Office of Education has provided grants to such education institutions to develop exhibits featuring Science On a Sphere (SOS) and create content for and evaluate audience impact. Currently, 20 public education institutions have permanent Science On a Sphere exhibits and 6 more will be installed soon. These institutions and others that are working to create and evaluate content for this system work collaboratively as a network to improve our collective knowledge about how to create educationally effective visualizations. Network members include other federal agencies, such as, NASA and the Dept. of Energy, and major museums such as Smithsonian and American Museum of Natural History, as well as a variety of mid-sized and small museums and universities. Although the audiences in these institutions vary widely in their scientific awareness and understanding, we find there are misconceptions and lack of familiarity with viewing visualizations that are common among the audiences. Through evaluations performed in these institutions we continue to evolve our understanding of how to create content that is understandable by those with minimal scientific literacy. The findings from our network will be presented including the importance of providing context, real-world connections and imagery to accompany the visualizations and the need for audience orientation before the visualizations are viewed. Additionally, we will review the publicly accessible virtual library housing over 200 datasets for SOS and any other real or virtual globe. These datasets represent contributions from NOAA, NASA, Dept. of Energy, and the public institutions that are displaying the spheres.

  18. Packed Planetary Systems

    NASA Astrophysics Data System (ADS)

    Barnes, R.; Greenberg, R.

    2005-08-01

    Planetary systems display a wide range of appearances, with apparently arbitrary values of semi-major axis, eccentricity, etc. We reduce the complexity of orbital configurations to a single value, δ , which is a measure of how close, over secular timescales ( ˜10,000 orbits), two consecutive planets come to each other. We measure this distance relative to the sum of the radii of their Hill spheres, sometimes referred to as mutual Hill radii (MHR). We determine the closest approach distance by numerically integrating the entire system on coplanar orbits, using minimum masses. For non-resonant systems, close approach occurs during apsidal alignment, either parallel or anti-parallel. For resonant pairs the distance at conjunction determines the closest approach distance. Previous analytic work found that planets on circular orbits were assuredly unstable if they came within 3.5 MHR (i.e. Gladman 1993; Chambers, Wetherill & Boss 1996). We find that most known pairs of jovian planets (including those in our solar system) come within 3.5 -- 7 MHR of each other. We also find that several systems are unstable (their closest approach distance is less than 3.5 MHR). These systems, if they are real, probably exist in an observationally permitted location somewhat different from the current best fit. In these cases, the planets' closest approach distance will most likely also be slightly larger than 3.5 MHR. Most pairs beyond 7 MHR probably experienced post-formation migration (i.e. tidal circularization, inward scattering of small bodies) which moved them further apart. This result is even more remarkable since we have used the minimum masses; most likely the systems are inclined to the line of sight, making the Hill spheres larger, and shrinking δ . This dense packing may reflect a tendency for planets to form as close together as they can without being dynamically unstable. This result further implies there may be a large number of smaller, currently undetectable companions packed in orbits around stars with known planets.

  19. Isolation of sphere-forming stem cells from the mouse inner ear.

    PubMed

    Oshima, Kazuo; Senn, Pascal; Heller, Stefan

    2009-01-01

    The mammalian inner ear has very limited ability to regenerate lost sensory hair cells. This deficiency becomes apparent when hair cell loss leads to hearing loss as a result of either ototoxic insult or the aging process. Coincidently, with this inability to regenerate lost hair cells, the adult cochlea does not appear to harbor cells with a proliferative capacity that could serve as progenitor cells for lost cells. In contrast, adult mammalian vestibular sensory epithelia display a limited ability for hair cell regeneration, and sphere-forming cells with stem cell features can be isolated from the adult murine vestibular system. The neonatal inner ear, however, does harbor sphere-forming stem cells residing in cochlear and vestibular tissues. Here, we provide protocols to isolate sphere-forming stem cells from neonatal vestibular and cochlear sensory epithelia as well as from the spiral ganglion. We further describe procedures for sphere propagation, cell differentiation, and characterization of inner ear cell types derived from spheres. Sphere-forming stem cells from the mouse inner ear are an important tool for the development of cellular replacement strategies of damaged inner ears and are a bona fide progenitor cell source for transplantation studies.

  20. Sphere forming method and apparatus

    NASA Technical Reports Server (NTRS)

    Youngberg, C. L.; Miller, C. G.; Stephens, J. B.; Finnerty, A. A. (Inventor)

    1983-01-01

    A system is provided for forming small accurately spherical objects. Preformed largely spherical objects are supported at the opening of a conduit on the update of hot gas emitted from the opening, so the object is in a molten state. The conduit is suddenly jerked away at a downward incline, to allow the molten object to drop in free fall, so that surface tension forms a precise sphere. The conduit portion that has the opening, lies in a moderate vacuum chamber, and the falling sphere passes through the chamber and through a briefly opened valve into a tall drop tower that contains a lower pressure, to allow the sphere to cool without deformation caused by falling through air.

  1. Brownian versus Newtonian devitrification of hard-sphere glasses

    NASA Astrophysics Data System (ADS)

    Montero de Hijes, Pablo; Rosales-Pelaez, Pablo; Valeriani, Chantal; Pusey, Peter N.; Sanz, Eduardo

    2017-08-01

    In a recent molecular dynamics simulation work it has been shown that glasses composed of hard spheres crystallize via cooperative, stochastic particle displacements called avalanches [E. Sanz et al., Proc. Natl. Acad. Sci. USA 111, 75 (2014), 10.1073/pnas.1308338110]. In this Rapid Communication we investigate if such a devitrification mechanism is also present when the dynamics is Brownian rather than Newtonian. The research is motivated in part by the fact that colloidal suspensions, an experimental realization of hard-sphere systems, undergo Brownian motion. We find that Brownian hard-sphere glasses do crystallize via avalanches with very similar characteristics to those found in the Newtonian case. We briefly discuss the implications of these findings for experiments on colloids.

  2. Decoding the Voluntourism Process: A Case Study of the Pay It Forward Tour

    ERIC Educational Resources Information Center

    Bailey, Andrew W.; Fernando, Irene K.

    2011-01-01

    "Voluntourism" refers to the use of "discretionary time and income to travel out of the sphere of regular activity to assist others in need" (McGehee & Santos, 2005, p. 760). These experiences have been shown to raise consciousness and increase interest in activism (McGehee, 2002; Wearing, 2001) and to build pro-social…

  3. Forging Vertical Linkages in the Public Sphere: School-Church Engagement for Social Justice

    ERIC Educational Resources Information Center

    Miller, Peter M.; Engel, Max T.

    2011-01-01

    Within the broad discussion of social justice in education, multiple conceptualizations of the term have been posited. Although there is no uniform notion of social justice, most would concur that, "Social justice, broadly defined, refers to a condition whereby all people are afforded fair opportunities to enjoy the benefits of society" (Miller,…

  4. Ball assisted device for analytical surface sampling

    DOEpatents

    ElNaggar, Mariam S; Van Berkel, Gary J; Covey, Thomas R

    2015-11-03

    A system for sampling a surface includes a sampling probe having a housing and a socket, and a rolling sampling sphere within the socket. The housing has a sampling fluid supply conduit and a sampling fluid exhaust conduit. The sampling fluid supply conduit supplies sampling fluid to the sampling sphere. The sampling fluid exhaust conduit has an inlet opening for receiving sampling fluid carried from the surface by the sampling sphere. A surface sampling probe and a method for sampling a surface are also disclosed.

  5. Vapor-liquid phase behavior of a size-asymmetric model of ionic fluids confined in a disordered matrix: The collective-variables-based approach

    NASA Astrophysics Data System (ADS)

    Patsahan, O. V.; Patsahan, T. M.; Holovko, M. F.

    2018-02-01

    We develop a theory based on the method of collective variables to study the vapor-liquid equilibrium of asymmetric ionic fluids confined in a disordered porous matrix. The approach allows us to formulate the perturbation theory using an extension of the scaled particle theory for a description of a reference system presented as a two-component hard-sphere fluid confined in a hard-sphere matrix. Treating an ionic fluid as a size- and charge-asymmetric primitive model (PM) we derive an explicit expression for the relevant chemical potential of a confined ionic system which takes into account the third-order correlations between ions. Using this expression, the phase diagrams for a size-asymmetric PM are calculated for different matrix porosities as well as for different sizes of matrix and fluid particles. It is observed that general trends of the coexistence curves with the matrix porosity are similar to those of simple fluids under disordered confinement, i.e., the coexistence region gets narrower with a decrease of porosity and, simultaneously, the reduced critical temperature Tc* and the critical density ρi,c * become lower. At the same time, our results suggest that an increase in size asymmetry of oppositely charged ions considerably affects the vapor-liquid diagrams leading to a faster decrease of Tc* and ρi,c * and even to a disappearance of the phase transition, especially for the case of small matrix particles.

  6. Unsteady sedimentation of a sphere in wormlike micellar fluids

    NASA Astrophysics Data System (ADS)

    Zhang, Yiran; Muller, Susan J.

    2018-04-01

    The unsteady sedimentation of a sphere in wormlike micellar fluids is studied experimentally through shear and extensional rheometry, sphere trajectory tracking, and particle image velocimetry. Unsteady sphere sedimentation characterized by fluctuations in the sphere settling velocity was observed for a range of sphere size and density in two non-shear-banding wormlike micellar solutions, a cetylpyridinium chloride (CpCl)-sodium salicylate (NaSal) solution and a cetyltrimethylammonium p-toluenesulfonate (CTAT)-NaCl solution. The onset of the transition from steady to unsteady sphere motion is characterized by an extensional Deborah number, D eext , defined locally in the negative wake of the falling sphere. This instability criterion is in agreement with previous findings by Mohammadigoushki and Muller [J. Rheol. 60, 587 (2016), 10.1122/1.4948800] in the wormlike micelle system of cetyltrimethylammonium bromide (CTAB) and NaSal, and appears to be universally valid independent of micelle chemistry or solution rheology (e.g., shear banding or not). Moreover, the frequency at which the sphere velocity fluctuates is found to be linearly correlated with an average shear Deborah number D es , which is a measure of the overall flow strength. This suggests that a constant critical strain is accumulated before the flow instability takes place in each velocity oscillation. The velocity fluctuations are found to become increasingly disordered with increasing elastic Mach number, M ae , indicating that the interactions between the flow instability and elastic wave propagation result in more chaotic velocity fluctuations.

  7. Accuracy of an infrared marker-based patient positioning system (ExacTrac®) for stereotactic body radiotherapy in localizing the planned isocenter using fiducial markers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Montes-Rodríguez, María de los Ángeles, E-mail: angy24538@yahoo.com; Mitsoura, Eleni; Hernández-Bojórquez, Mariana

    2014-11-07

    Stereotactic Body Radiation Therapy (SBRT) requires a controlled immobilization and position monitoring of patient and target. The purpose of this work is to analyze the performance of the imaging system ExacTrac® (ETX) using infrared and fiducial markers. Materials and methods: In order to assure the accuracy of isocenter localization, a Quality Assurance procedure was applied using an infrared marker-based positioning system. Scans were acquired of an inhouse-agar gel and solid water phantom with infrared spheres. In the inner part of the phantom, three reference markers were delineated as reference and one pellet was place internally; which was assigned as themore » isocenter. The iPlan® RT Dose treatment planning system. Images were exported to the ETX console. Images were acquired with the ETX to check the correctness of the isocenter placement. Adjustments were made in 6D the reference markers were used to fuse the images. Couch shifts were registered. The procedure was repeated for verification purposes. Results: The data recorded of the verifications in translational and rotational movements showed averaged 3D spatial uncertainties of 0.31 ± 0.42 mm respectively 0.82° ± 0.46° in the phantom and the first correction of these uncertainties were of 1.51 ± 1.14 mm respectively and 1.37° ± 0.61°. Conclusions: This study shows a high accuracy and repeatability in positioning the selected isocenter. The ETX-system for verifying the treatment isocenter position has the ability to monitor the tracing position of interest, making it possible to be used for SBRT positioning within uncertainty ≤1mm.« less

  8. A Framework for Testing Scientific Software: A Case Study of Testing Amsterdam Discrete Dipole Approximation Software

    NASA Astrophysics Data System (ADS)

    Shao, Hongbing

    Software testing with scientific software systems often suffers from test oracle problem, i.e., lack of test oracles. Amsterdam discrete dipole approximation code (ADDA) is a scientific software system that can be used to simulate light scattering of scatterers of various types. Testing of ADDA suffers from "test oracle problem". In this thesis work, I established a testing framework to test scientific software systems and evaluated this framework using ADDA as a case study. To test ADDA, I first used CMMIE code as the pseudo oracle to test ADDA in simulating light scattering of a homogeneous sphere scatterer. Comparable results were obtained between ADDA and CMMIE code. This validated ADDA for use with homogeneous sphere scatterers. Then I used experimental result obtained for light scattering of a homogeneous sphere to validate use of ADDA with sphere scatterers. ADDA produced light scattering simulation comparable to the experimentally measured result. This further validated the use of ADDA for simulating light scattering of sphere scatterers. Then I used metamorphic testing to generate test cases covering scatterers of various geometries, orientations, homogeneity or non-homogeneity. ADDA was tested under each of these test cases and all tests passed. The use of statistical analysis together with metamorphic testing is discussed as a future direction. In short, using ADDA as a case study, I established a testing framework, including use of pseudo oracles, experimental results and the metamorphic testing techniques to test scientific software systems that suffer from test oracle problems. Each of these techniques is necessary and contributes to the testing of the software under test.

  9. Lay Definitions of Happiness across Nations: The Primacy of Inner Harmony and Relational Connectedness

    PubMed Central

    Delle Fave, Antonella; Brdar, Ingrid; Wissing, Marié P.; Araujo, Ulisses; Castro Solano, Alejandro; Freire, Teresa; Hernández-Pozo, María Del Rocío; Jose, Paul; Martos, Tamás; Nafstad, Hilde E.; Nakamura, Jeanne; Singh, Kamlesh; Soosai-Nathan, Lawrence

    2016-01-01

    In well-being research the term happiness is often used as synonymous with life satisfaction. However, little is known about lay people's understanding of happiness. Building on the available literature, this study explored lay definitions of happiness across nations and cultural dimensions, analyzing their components and relationship with participants' demographic features. Participants were 2799 adults (age range = 30–60, 50% women) living in urban areas of Argentina, Brazil, Croatia, Hungary, India, Italy, Mexico, New Zealand, Norway, Portugal, South Africa, and United States. They completed the Eudaimonic and Hedonic Happiness Investigation (EHHI), reporting, among other information, their own definition of happiness. Answers comprised definitions referring to a broad range of life domains, covering both the contextual-social sphere and the psychological sphere. Across countries and with little variation by age and gender, inner harmony predominated among psychological definitions, and family and social relationships among contextual definitions. Whereas relationships are widely acknowledged as basic happiness components, inner harmony is substantially neglected. Nevertheless, its cross-national primacy, together with relations, is consistent with the view of an ontological interconnectedness characterizing living systems, shared by several conceptual frameworks across disciplines and cultures. At the methodological level, these findings suggest the potential of a bottom-up, mixed method approach to contextualize psychological dimensions within culture and lay understanding. PMID:26858677

  10. Lay Definitions of Happiness across Nations: The Primacy of Inner Harmony and Relational Connectedness.

    PubMed

    Delle Fave, Antonella; Brdar, Ingrid; Wissing, Marié P; Araujo, Ulisses; Castro Solano, Alejandro; Freire, Teresa; Hernández-Pozo, María Del Rocío; Jose, Paul; Martos, Tamás; Nafstad, Hilde E; Nakamura, Jeanne; Singh, Kamlesh; Soosai-Nathan, Lawrence

    2016-01-01

    In well-being research the term happiness is often used as synonymous with life satisfaction. However, little is known about lay people's understanding of happiness. Building on the available literature, this study explored lay definitions of happiness across nations and cultural dimensions, analyzing their components and relationship with participants' demographic features. Participants were 2799 adults (age range = 30-60, 50% women) living in urban areas of Argentina, Brazil, Croatia, Hungary, India, Italy, Mexico, New Zealand, Norway, Portugal, South Africa, and United States. They completed the Eudaimonic and Hedonic Happiness Investigation (EHHI), reporting, among other information, their own definition of happiness. Answers comprised definitions referring to a broad range of life domains, covering both the contextual-social sphere and the psychological sphere. Across countries and with little variation by age and gender, inner harmony predominated among psychological definitions, and family and social relationships among contextual definitions. Whereas relationships are widely acknowledged as basic happiness components, inner harmony is substantially neglected. Nevertheless, its cross-national primacy, together with relations, is consistent with the view of an ontological interconnectedness characterizing living systems, shared by several conceptual frameworks across disciplines and cultures. At the methodological level, these findings suggest the potential of a bottom-up, mixed method approach to contextualize psychological dimensions within culture and lay understanding.

  11. Methods for quantitative infrared directional-hemispherical and diffuse reflectance measurements using an FTIR and a commercial integrating sphere

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blake, Thomas A.; Johnson, Timothy J.; Tonkyn, Russell G.

    Infrared integrating sphere measurements of solid samples are important in providing reference data for contact, standoff and remote sensing applications. At the Pacific Northwest National Laboratory (PNNL) we have developed protocols to measure both the directional-hemispherical ( and diffuse (d) reflectances of powders, liquids, and disks of powders and solid materials using a commercially available, matte gold-coated integrating sphere and Fourier transform infrared spectrometer. Detailed descriptions of the sphere alignment and its use for making these reflectance measurements are given. Diffuse reflectance values were found to be dependent on the bidirectional reflection distribution function (BRDF) of the sample and themore » solid angle intercepted by the sphere’s specular exclusion port. To determine how well the sphere and protocols produce quantitative reflectance data, measurements were made of three diffuse and two specular standards prepared by the National institute of Standards and Technology (NIST, USA), LabSphere Infragold and Spectralon standards, hand-loaded sulfur and talc powder samples, and water. The five NIST standards behaved as expected: the three diffuse standards had a high degree of “diffuseness,” d/ = D > 0.9, whereas the two specular standards had D ≤ 0.03. The average absolute differences between the NIST and PNNL measurements of the NIST standards for both directional-hemispherical and diffuse reflectances are on the order of 0.01 reflectance units. Other quantitative differences between the PNNL-measured and calibration (where available) or literature reflectance values for these standards and materials are given and the possible origins of discrepancies are discussed. Random uncertainties and estimates of systematic uncertainties are presented. Corrections necessary to provide better agreement between the PNNL reflectance values as measured for the NIST standards and the NIST reflectance values for these same standards are also discussed.« less

  12. Parallelization of combinatorial search when solving knapsack optimization problem on computing systems based on multicore processors

    NASA Astrophysics Data System (ADS)

    Rahman, P. A.

    2018-05-01

    This scientific paper deals with the model of the knapsack optimization problem and method of its solving based on directed combinatorial search in the boolean space. The offered by the author specialized mathematical model of decomposition of the search-zone to the separate search-spheres and the algorithm of distribution of the search-spheres to the different cores of the multi-core processor are also discussed. The paper also provides an example of decomposition of the search-zone to the several search-spheres and distribution of the search-spheres to the different cores of the quad-core processor. Finally, an offered by the author formula for estimation of the theoretical maximum of the computational acceleration, which can be achieved due to the parallelization of the search-zone to the search-spheres on the unlimited number of the processor cores, is also given.

  13. Ultrasonic cavitation of molten gallium: formation of micro- and nano-spheres.

    PubMed

    Kumar, Vijay Bhooshan; Gedanken, Aharon; Kimmel, Giora; Porat, Ze'ev

    2014-05-01

    Pure gallium has a low melting point (29.8°C) and can be melted in warm water or organic liquids, thus forming two immiscible liquid phases. Irradiation of this system with ultrasonic energy causes cavitation and dispersion of the molten gallium as microscopic spheres. The resultant spheres were found to have radii range of 0.2-5 μm and they do not coalesce upon cessation of irradiation, although the ambient temperature is well above the m.p. of gallium. It was found that the spheres formed in water are covered with crystallites of GaO(OH), whereas those formed in organic liquids (hexane and n-dodecane) are smooth, lacking such crystallites. However, Raman spectroscopy revealed that the spheres formed in organic liquids are coated with a carbon film. The latter may be the factor preventing their coalescence at temperatures above the m.p. of gallium. Copyright © 2013 Elsevier B.V. All rights reserved.

  14. Structural and Acoustic Damping Characteristics of Polyimide Microspheres

    NASA Technical Reports Server (NTRS)

    Palumbo, Daniel L.; Park, Junhong

    2005-01-01

    A broad range of tests have been performed to evaluate the capability of tiny lightweight polyimide spheres to reduce sound and vibration. The types of testing includes impedance tube measurement of propagation constant, sound power insertion loss for single and double wall systems, particle frame wave characterization and beam vibration reduction. The tests were performed using spheres made of two types of polyimide and with varying diameter. Baseline results were established using common noise reduction treatment materials such as fiberglass and foam. The spheres were difficult to test due to their inherent mobility. Most tests required some adaptation to contain the spheres. One test returned obvious non-linear behavior, a result which has come to be expected for treatments of this type. The polyimide spheres are found to be a competent treatment for both sound and vibration energy with the reservation that more work needs to be done to better characterize the non-linear behavior.

  15. Constant angular velocity of the wrist during the lifting of a sphere.

    PubMed

    Chappell, P H; Metcalf, C D; Burridge, J H; Yule, V T; Pickering, R M

    2010-05-01

    The primary objective of the experiments was to investigate the wrist motion of a person while they were carrying out a prehensile task from a clinical hand function test. A six-camera movement system was used to observe the wrist motion of 10 participants. A very light sphere and a heavy sphere were used in the experiments to study any mass effects. While seated at a table, a participant moved a sphere over a small obstacle using their dominant hand. The participants were observed to move their wrist at a constant angular velocity. This phenomenon has not been reported previously. Theoretically, the muscles of the wrist provide an impulse of force at the start of the rotation while the forearm maintains a constant vertical force on a sphere. Light-heavy mean differences for the velocities, absolute velocities, angles and times taken showed no significant differences (p = 0.05).

  16. Hollow boron nitride nanospheres as boron reservoir for prostate cancer treatment

    PubMed Central

    Li, Xia; Wang, Xiupeng; Zhang, Jun; Hanagata, Nobutaka; Wang, Xuebin; Weng, Qunhong; Ito, Atsuo; Bando, Yoshio; Golberg, Dmitri

    2017-01-01

    High global incidence of prostate cancer has led to a focus on prevention and treatment strategies to reduce the impact of this disease in public health. Boron compounds are increasingly recognized as preventative and chemotherapeutic agents. However, systemic administration of soluble boron compounds is hampered by their short half-life and low effectiveness. Here we report on hollow boron nitride (BN) spheres with controlled crystallinity and boron release that decrease cell viability and increase prostate cancer cell apoptosis. In vivo experiments on subcutaneous tumour mouse models treated with BN spheres demonstrated significant suppression of tumour growth. An orthotopic tumour growth model was also utilized and further confirmed the in vivo anti-cancer efficacy of BN spheres. Moreover, the administration of hollow BN spheres with paclitaxel leads to synergetic effects in the suppression of tumour growth. The work demonstrates that hollow BN spheres may function as a new agent for prostate cancer treatment. PMID:28059072

  17. Area law microstate entropy from criticality and spherical symmetry

    NASA Astrophysics Data System (ADS)

    Dvali, Gia

    2018-05-01

    It is often assumed that the area law of microstate entropy and the holography are intrinsic properties exclusively of the gravitational systems, such as black holes. We construct a nongravitational model that exhibits an entropy that scales as area of a sphere of one dimension less. It is represented by a nonrelativistic bosonic field living on a d -dimensional sphere of radius R and experiencing an angular-momentum-dependent attractive interaction. We show that the system possesses a quantum critical point with the emergent gapless modes. Their number is equal to the area of a d -1 -dimensional sphere of the same radius R . These gapless modes create an exponentially large number of degenerate microstates with the corresponding microstate entropy given by the area of the same d -1 -dimensional sphere. Thanks to a double-scaling limit, the counting of the entropy and of the number of the gapless modes is made exact. The phenomenon takes place for arbitrary number of dimensions and can be viewed as a version of holography.

  18. Linear and nonlinear response in sheared soft spheres

    NASA Astrophysics Data System (ADS)

    Tighe, Brian

    2013-11-01

    Packings of soft spheres provide an idealized model of foams, emulsions, and grains, while also serving as the canonical example of a system undergoing a jamming transition. Packings' mechanical response has now been studied exhaustively in the context of ``strict linear response,'' i.e. by linearizing about a stable static packing and solving the resulting equations of motion. Both because the system is close to a critical point and because the soft sphere pair potential is non-analytic at the point of contact, it is reasonable to ask under what circumstances strict linear response provides a good approximation to the actual response. We simulate sheared soft sphere packings close to jamming and identify two distinct strain scales: (i) the scale on which strict linear response fails, coinciding with a topological change in the packing's contact network; and (ii) the scale on which linear superposition of the averaged stress-strain curve breaks down. This latter scale provides a ``weak linear response'' criterion and is likely to be more experimentally relevant.

  19. Study of thermodynamic properties of liquid binary alloys by a pseudopotential method

    NASA Astrophysics Data System (ADS)

    Vora, Aditya M.

    2010-11-01

    On the basis of the Percus-Yevick hard-sphere model as a reference system and the Gibbs-Bogoliubov inequality, a thermodynamic perturbation method is applied with the use of the well-known model potential. By applying a variational method, the hard-core diameters are found which correspond to a minimum free energy. With this procedure, the thermodynamic properties such as the internal energy, entropy, Helmholtz free energy, entropy of mixing, and heat of mixing are computed for liquid NaK binary systems. The influence of the local-field correction functions of Hartree, Taylor, Ichimaru-Utsumi, Farid-Heine-Engel-Robertson, and Sarkar-Sen-Haldar-Roy is also investigated. The computed excess entropy is in agreement with available experimental data in the case of liquid alloys, whereas the agreement for the heat of mixing is poor. This may be due to the sensitivity of the latter to the potential parameters and dielectric function.

  20. Lie theory and control systems defined on spheres

    NASA Technical Reports Server (NTRS)

    Brockett, R. W.

    1972-01-01

    It is shown that in constructing a theory for the most elementary class of control problems defined on spheres, some results from the Lie theory play a natural role. To understand controllability, optimal control, and certain properties of stochastic equations, Lie theoretic ideas are needed. The framework considered here is the most natural departure from the usual linear system/vector space problems which have dominated control systems literature. For this reason results are compared with those previously available for the finite dimensional vector space case.

  1. SU-F-BRA-12: End-User Oriented Tools and Procedures for Testing Brachytherapy TPSs Employing MBDCAs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Peppa, V; Pappas, E; Lahanas, V

    2015-06-15

    Purpose: To develop user-oriented tools for commissioning and dosimetry testing of {sup 192}Ir brachytherapy treatment planning systems (TPSs) employing model based dose calculation algorithms (MBDCAs). Methods: A software tool (BrachyGuide) has been developed for the automatic generation of MCNP6 input files from any CT based plan exported in DICOM RT format from Elekta and Varian TPSs. BrachyGuide also facilitates the evaluation of imported Monte Carlo (MC) and TPS dose distributions in terms of % dose differences and gamma index (CT overlaid colormaps or relative frequency plots) as well as DVHs and related indices. For users not equipped to perform MC,more » a set of computational models was prepared in DICOM format, accompanied by treatment plans and corresponding MCNP6 generated reference data. BrachyGuide can then be used to compare institutional and reference data as per TG186. The model set includes a water sphere with the MBDCA WG {sup 192}Ir source placed centrically and in two eccentric positions, a water sphere with cubic bone and lung inhomogeneities and a five source dwells plan, and a patient equivalent model with an Accelerated Partial Breast Irradiation (APBI) plan. Results: The tools developed were used for the dosimetry testing of the Acuros and ACE MBDCAs implemented in BrachyVision v.13 and Oncentra Brachy v.4.5, respectively. Findings were consistent with previous results in the literature. Besides points close to the source dwells, Acuros was found to agree within type A uncertainties with the reference MC results. Differences greater than MC type A uncertainty were observed for ACE at distances >5cm from the source dwells and in bone. Conclusion: The tools developed are efficient for brachytherapy MBDCA planning commissioning and testing. Since they are appropriate for distribution over the web, they will be put at the AAPM WG MBDCA’s disposal. Research co-financed by the ESF and Greek funds. NSRF operational Program: Education and Lifelong Learning Investing in Knowledge Society-Aristeia. Varian Medical Systems and Nucletron, an Elekta company provided access to TPSs for research purposes. Miss Peppa was supported by IKY-fellowships of excellence for postgraduate studies in Greece,Siemens Program.« less

  2. Levitation and lateral forces between a point magnetic dipole and a superconducting sphere

    NASA Astrophysics Data System (ADS)

    H, M. Al-Khateeb; M, K. Alqadi; F, Y. Alzoubi; B, Albiss; M, K. Hasan (Qaseer; N, Y. Ayoub

    2016-05-01

    The dipole-dipole interaction model is employed to investigate the angular dependence of the levitation and lateral forces acting on a small magnet in an anti-symmetric magnet/superconducting sphere system. Breaking the symmetry of the system enables us to study the lateral force which is important in the stability of the magnet above a superconducting sphere in the Meissner state. Under the assumption that the lateral displacement of the magnet is small compared to the physical dimensions of our proposed system, analytical expressions are obtained for the levitation and lateral forces as a function of the geometrical parameters of the superconductor as well as the height, the lateral displacement, and the orientation of the magnetic moment of the magnet. The dependence of the levitation force on the height of the levitating magnet is similar to that in the symmetric magnet/superconducting sphere system within the range of proposed lateral displacements. It is found that the levitation force is linearly dependent on the lateral displacement whereas the lateral force is independent of this displacement. A sinusoidal variation of both forces as a function of the polar and azimuthal angles specifying the orientation of the magnetic moment is observed. The relationship between the stability and the orientation of the magnetic moment is discussed for different orientations.

  3. The influence of size and charge of chitosan/polyglutamic acid hollow spheres on cellular internalization, viability and blood compatibility.

    PubMed

    Dash, Biraja C; Réthoré, Gildas; Monaghan, Michael; Fitzgerald, Kathleen; Gallagher, William; Pandit, Abhay

    2010-11-01

    Polymeric hollow spheres can be tailored as efficient carriers of various therapeutic molecules due to their tunable properties. However, the entry of these synthetic vehicles into cells, their cell viability and blood compatibility depend on their physical and chemical properties e.g. size, surface charge. Herein, we report the effect of size and surface charge on cell viability and cellular internalization behaviour and their effect on various blood components using chitosan/polyglutamic acid hollow spheres as a model system. Negatively charged chitosan/polyglutamic acid hollow spheres of various sizes 100, 300, 500 and 1000 nm were fabricated using a template based method and covalently surface modified using linear polyethylene glycol and methoxyethanol amine to create a gradient of surface charge from negative to neutrally charged spheres respectively. The results here suggest that both size and surface charge have a significant influence on the sphere's behaviour, most prominently on haemolysis, platelet activation, plasma recalcification time, cell viability and internalization over time. Additionally, cellular internalization behaviour and viability was found to vary with different cell types. These results are in agreement with those of inorganic spheres and liposomes, and can serve as guidelines for tailoring polymeric solid spheres for specific desired applications in biological and pharmaceutical fields, including the design of nanometer to submicron-sized delivery vehicles. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  4. Equatorial symmetry of Boussinesq convective solutions in a rotating spherical shell allowing rotation of the inner and outer spheres

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kimura, Keiji; Takehiro, Shin-ichi; Yamada, Michio

    2014-08-15

    We investigate properties of convective solutions of the Boussinesq thermal convection in a moderately rotating spherical shell allowing the respective rotation of the inner and outer spheres due to the viscous torque of the fluid. The ratio of the inner and outer radii of the spheres, the Prandtl number, and the Taylor number are fixed to 0.4, 1, and 500{sup 2}, respectively. The Rayleigh number is varied from 2.6 × 10{sup 4} to 3.4 × 10{sup 4}. In this parameter range, the behaviours of obtained asymptotic convective solutions are almost similar to those in the system whose inner and outermore » spheres are restricted to rotate with the same constant angular velocity, although the difference is found in the transition process to chaotic solutions. The convective solution changes from an equatorially symmetric quasi-periodic one to an equatorially symmetric chaotic one, and further to an equatorially asymmetric chaotic one, as the Rayleigh number is increased. This is in contrast to the transition in the system whose inner and outer spheres are assumed to rotate with the same constant angular velocity, where the convective solution changes from an equatorially symmetric quasi-periodic one, to an equatorially asymmetric quasi-periodic one, and to equatorially asymmetric chaotic one. The inner sphere rotates in the retrograde direction on average in the parameter range; however, it sometimes undergoes the prograde rotation when the convective solution becomes chaotic.« less

  5. Light scattering of a Bessel beam by a nucleated biological cell: An eccentric sphere model

    NASA Astrophysics Data System (ADS)

    Wang, Jia Jie; Han, Yi Ping; Chang, Jiao Yong; Chen, Zhu Yang

    2018-02-01

    Within the framework of generalized Lorenz-Mie theory (GLMT), an eccentrically stratified dielectric sphere model illuminated by an arbitrarily incident Bessel beam is applied to investigate the scattering characteristics of a single nucleated biological cell. The Bessel beam propagating in an arbitrary direction is expanded in terms of vector spherical wave functions (VSWFs), where the beam shape coefficients (BSCs) are calculated rigorously in a closed analytical form. The effects of the half-cone angle of Bessel beam, the location of the particle in the beam, the size ratio of nucleus to cell, and the location of the nucleus inside the cell on the scattering properties of a nucleated cell are analyzed. The results provide useful references for optical diagnostic and imaging of particle having nucleated structure.

  6. Modelling mass diffusion for a multi-layer sphere immersed in a semi-infinite medium: application to drug delivery.

    PubMed

    Carr, Elliot J; Pontrelli, Giuseppe

    2018-04-12

    We present a general mechanistic model of mass diffusion for a composite sphere placed in a large ambient medium. The multi-layer problem is described by a system of diffusion equations coupled via interlayer boundary conditions such as those imposing a finite mass resistance at the external surface of the sphere. While the work is applicable to the generic problem of heat or mass transfer in a multi-layer sphere, the analysis and results are presented in the context of drug kinetics for desorbing and absorbing spherical microcapsules. We derive an analytical solution for the concentration in the sphere and in the surrounding medium that avoids any artificial truncation at a finite distance. The closed-form solution in each concentric layer is expressed in terms of a suitably-defined inverse Laplace transform that can be evaluated numerically. Concentration profiles and drug mass curves in the spherical layers and in the external environment are presented and the dependency of the solution on the mass transfer coefficient at the surface of the sphere analyzed. Copyright © 2018 Elsevier Inc. All rights reserved.

  7. Modified release matrix prepared by compaction of spheres containing waxy material.

    PubMed

    Bado, L; Ghaly, E S

    1995-09-01

    In this study, chlorpheniramine maleate spheres were prepared by the extruder/marumerizer. A new waxy material, Gelucire 50/02 at three levels (10%, 30% and 50%) was added and Avicel PH-101 was used as spheronizing material. The drug was incorporated into the waxy material by two methods. The first was the direct method, in which the drug (10%), wax and Avicel PH-101 were mixed together. The second was the fusion method, in which the drug was dispersed in the melted wax and the solidified mass was milled and mixed with Avicel PH-101. The data obtained indicated that simple addition of waxy material into chlorpheniramine maleate-Avicel PH-101 spheres interrupted matrix formation and increased drug release. Also in this study, a multiparticulate delivery system was prepared successfully by compaction of spheres into tablets. Tablets compacted from spheres prepared by fusion method gave less drug release than those compacted from spheres of the same composition but prepared with direct method. As the level of wax was increased in tablet formulation, drug release was decreased.

  8. Dynamics of Three Vortices on a Sphere

    NASA Astrophysics Data System (ADS)

    Borisov, Alexey V.; Mamaev, Ivan S.; Kilin, Alexander A.

    2018-01-01

    This paper is concerned with the dynamics of vortices on a sphere. It is shown that, as a result of reduction, the problem reduces to investigating a system with a nonlinear Poisson bracket. The topology of a symplectic leaf in the case of three vortices is studied.

  9. In vitro and in vivo evaluation of strontium-containing nanostructured carbonated hydroxyapatite/sodium alginate for sinus lift in rabbits.

    PubMed

    Valiense, Helder; Barreto, Mauricio; Resende, Rodrigo F; Alves, Adriana T; Rossi, Alexandre M; Mavropoulos, Elena; Granjeiro, José M; Calasans-Maia, Mônica D

    2016-02-01

    Various synthetic bone substitutes have been developed to reconstruct bone defects. One of the most prevalent ceramics in bone treatment is hydroxyapatite (HA) that is a useful material as bone substitute, however, with a low rate of biodegradation. Its structure allows isomorphic cationic and anionic substitutions to be easily introduced, which can alter the crystallinity, morphology, biocompatibility, and osteoconductivity. The objective of this study was to investigate the in vitro and in vivo biological responses to strontium-containing nanostructured carbonated HA/sodium alginate (SrCHA) spheres (425<ϕ <600 μm) that were used for sinus lifts in rabbits using nanostructured carbonated HA/sodium alginate (CHA) as a reference. Cytocompatibility was determined using a multiparametric assay after exposing murine preosteoblasts to the extracts of these materials. Twelve male and female rabbits underwent bilateral sinus lift procedures and were divided into two groups (CHA or SrCHA) and in two experimental periods (4 and 12 weeks), for microscopic and histomorphometric analyses. The in vitro test revealed the overall viability of the cells exposed to the CHA and SrCHA extracts; thus, these extracts were considered cytocompatible, which was confirmed by three different parameters in the in vitro tests. The histological analysis showed chronic inflammation with a prevalence of macrophages around the CHA spheres after 4 weeks, and this inflammation decreased after 12 weeks. Bone formation was observed in both groups, and smaller quantities of SrCHA spheres were observed after 12 weeks, indicating greater bioresorption of SrCHA than CHA. SrCHA spheres are biocompatible and osteoconductive and undergo bioresorption earlier than CHA spheres. © 2015 Wiley Periodicals, Inc.

  10. Measurement of blood flow through the retinal circulation of the cat during normoxia and hypoxemia using fluorescent microspheres.

    PubMed

    Ahmed, J; Pulfer, M K; Linsenmeier, R A

    2001-09-01

    The most successful method for measuring absolute blood flow rate through the retinal circulation has been the use of radioactive microspheres. The purpose of this study was to develop a microsphere method that did not have the drawbacks associated with radioactivity and to use this method to make measurements of retinal blood flow in the cat. Blood flow measurements were made by injecting 15-microm-diameter polystyrene microspheres into the left ventricle of anesthetized, artificially ventilated cats. These microspheres were labeled with one of three fluorescent dyes. Retinal blood flow measurements were made by determining the number of spheres that were embedded in the retina and comparing them to the number found in a reference sample. Spheres in the retina were counted by making retinal whole mounts and taking retinal images with a CCD camera mounted on an epifluorescence microscope equipped with filter sets appropriate for imaging the dyes used to label the spheres. Blood flow measurements made under normal conditions showed a mean retinal blood flow of 19.8 +/- 12.4 ml/min 100 g tissue (mean +/- SD; n = 15 cats). Since the retinal circulation perfuses only the inner half of the retina, the effective flow rate in that region is about twice this value. RBF increased during hypoxemia (P(a)O2 < 42 mm Hg) to 336% of the normoxic value on average. Analysis of sphere deposition patterns showed that the central retina had a higher blood flow than the peripheral retina, although this difference was significant only during hypoxemia. We conclude that even with a relatively small number of spheres deposited in the retina, the technique can reveal important properties of the retinal circulation. Copyright 2001 Academic Press.

  11. Pioneers and laggards - is the effect of gender equality on health dependent on context?

    PubMed

    Backhans, Mona Christina; Burström, Bo; Lindholm, Lars; Månsdotter, Anna

    2009-04-01

    This study combines data at individual and area level to examine interactions between equality within couples and gender equality in the municipality in which individuals live. The research question is whether the context impacts on the association between gender equality and health. The material consists of data on 37,423 men and 37,616 women in 279 Swedish municipalities, who had their first child in 1978. The couples were classified according to indicators of their level of gender equality in 1980 in the public sphere (occupation and income) and private sphere (child care leave and parental leave) compared to that of their municipality. The health outcome is compensated days from sickness insurance during 1986-1999 with a cut-off at the 85% percentile. Data were analysed using logistic regression with the overall odds as reference. The results concerning gender equality in the private sphere show that among fathers, those who are equal in an equal municipality have lower levels of sick leave than the average while laggards (less equal than their municipality) and modest laggards have higher levels. In the public sphere, pioneers (more equal t han their municipality) fare better than the average while laggards fare worse. For mothers, those who are traditional in their roles in the public sphere are protected from high levels of sick leave, while the reverse is true for those who are equal. Traditional mothers in a traditional municipality have the lowest level of sick leave and pioneers the highest. These results show that there are distinct benefits as well as disadvantages to being a gender pioneer and/or a laggard in comparison to your municipality. The associations are markedly different for men and women.

  12. Scaled Particle Theory for Multicomponent Hard Sphere Fluids Confined in Random Porous Media.

    PubMed

    Chen, W; Zhao, S L; Holovko, M; Chen, X S; Dong, W

    2016-06-23

    The formulation of scaled particle theory (SPT) is presented for a quite general model of fluids confined in a random porous media, i.e., a multicomponent hard sphere (HS) fluid in a multicomponent hard sphere or a multicomponent overlapping hard sphere (OHS) matrix. The analytical expressions for pressure, Helmholtz free energy, and chemical potential are derived. The thermodynamic consistency of the proposed theory is established. Moreover, we show that there is an isomorphism between the SPT for a multicomponent system and that for a one-component system. Results from grand canonical ensemble Monte Carlo simulations are also presented for a binary HS mixture in a one-component HS or a one-component OHS matrix. The accuracy of various variants derived from the basic SPT formulation is appraised against the simulation results. Scaled particle theory, initially formulated for a bulk HS fluid, has not only provided an analytical tool for calculating thermodynamic properties of HS fluid but also helped to gain very useful insight for elaborating other theoretical approaches such as the fundamental measure theory (FMT). We expect that the general SPT for multicomponent systems developed in this work can contribute to the study of confined fluids in a similar way.

  13. Granular self-organization by autotuning of friction.

    PubMed

    Kumar, Deepak; Nitsure, Nitin; Bhattacharya, S; Ghosh, Shankar

    2015-09-15

    A monolayer of granular spheres in a cylindrical vial, driven continuously by an orbital shaker and subjected to a symmetric confining centrifugal potential, self-organizes to form a distinctively asymmetric structure which occupies only the rear half-space. It is marked by a sharp leading edge at the potential minimum and a curved rear. The area of the structure obeys a power-law scaling with the number of spheres. Imaging shows that the regulation of motion of individual spheres occurs via toggling between two types of motion, namely, rolling and sliding. A low density of weakly frictional rollers congregates near the sharp leading edge whereas a denser rear comprises highly frictional sliders. Experiments further suggest that because the rolling and sliding friction coefficients differ substantially, the spheres acquire a local time-averaged coefficient of friction within a large range of intermediate values in the system. The various sets of spatial and temporal configurations of the rollers and sliders constitute the internal states of the system. Experiments demonstrate and simulations confirm that the global features of the structure are maintained robustly by autotuning of friction through these internal states, providing a previously unidentified route to self-organization of a many-body system.

  14. The Effect of Formulation Excipients and Thermal Treatment on the Release Properties of Lisinopril Spheres and Tablets.

    PubMed

    Amador Ríos, Zoriely; Ghaly, Evone Shehata

    2015-01-01

    Multiparticulate systems are used in the development of controlled release systems. The objective of this study was to determine the effect of the wax level, the type of excipient, and the exposure of the tablets to thermal treatment on drug release. Spheres from multiparticulate system with different wax levels and excipients were developed using the drug Lisinopril and compressed into tablets; these tablets were analyzed to determine the drug release. All tablets contained constant level of Lisinopril (10% w/w) and Compritol (30% and 50% w/w). Also, as a diluent, all of them contained 30% w/w Avicel and 30% w/w dibasic calcium phosphate or lactose, or 60% Avicel. Tablets compacted from spheres prepared by extruder/marumerizer and using 30% w/w lipid and 60% Avicel released 84% of drug at six hours of dissolution testing, while tablets of the same composition but prepared using 30% dibasic calcium phosphate and 30% Avicel released 101%. When the tablets were thermally treated, the drug release reduced. As the percent of lipid increased in the formulation, the drug release decreased. Compaction of tablets prepared from spheres with wax has potential for controlling the drug release.

  15. A Multiple Sphere T-Matrix Fortran Code for Use on Parallel Computer Clusters

    NASA Technical Reports Server (NTRS)

    Mackowski, D. W.; Mishchenko, M. I.

    2011-01-01

    A general-purpose Fortran-90 code for calculation of the electromagnetic scattering and absorption properties of multiple sphere clusters is described. The code can calculate the efficiency factors and scattering matrix elements of the cluster for either fixed or random orientation with respect to the incident beam and for plane wave or localized- approximation Gaussian incident fields. In addition, the code can calculate maps of the electric field both interior and exterior to the spheres.The code is written with message passing interface instructions to enable the use on distributed memory compute clusters, and for such platforms the code can make feasible the calculation of absorption, scattering, and general EM characteristics of systems containing several thousand spheres.

  16. Formation of metallic and metallic-glass hollow spheres and their solidification characteristics

    NASA Technical Reports Server (NTRS)

    Lee, M. C.

    1985-01-01

    Various metals and metallic glass systems have bene processed into hollow spheres with sizes ranging from 3 mm to 440 microns in diameter. The technique for the formation of the large hollow spheres, in general, is based on the fluid-dynamic instability of a hollow annular jet. A refined technique has also been developed for microshell formation, in which discrete bubbles are injected into the stream of the molten material and individually 'flushed' out at a frequency related to the Rayleigh jet instability. The surfaces of those spheres of all sizes exhibit a range of contrasting solidification behaviors and characteristics. Metal shells of varying materials, sizes, aspect ratios, sphericity and concentricity have many useful and novel applications.

  17. One-step synthesis of hierarchically porous hybrid TiO2 hollow spheres with high photocatalytic activity

    NASA Astrophysics Data System (ADS)

    Liu, Ruiping; Ren, Feng; Yang, Jinlin; Su, Weiming; Sun, Zhiming; Zhang, Lei; Wang, Chang-an

    2016-03-01

    Hierarchically porous hybrid TiO2 hollow spheres were solvothermally synthesized successfully by using tetrabutyl titanate as titanium precursor and hydrated metal sulfates as soft templates. The as-prepared TiO2 spheres with hierarchically pore structures and high specific surface area and pore volume consisted of highly crystallized anatase TiO2 nanocrystals hybridized with a small amount of metal oxide from the hydrated sulfate. The proposed hydrated-sulfate assisted solvothermal (HAS) synthesis strategy was demonstrated to be widely applicable to various systems. Evaluation of the hybrid TiO2 hollow spheres for the photo-decomposition of methyl orange (MO) under visible-light irradiation revealed that they exhibited excellent photocatalytic activity and durability.

  18. Three-Dimensional Accuracy of Digital Static Interocclusal Registration by Three Intraoral Scanner Systems.

    PubMed

    Wong, Kuan Yee; Esguerra, Roxanna Jean; Chia, Vanessa Ai Ping; Tan, Ying Han; Tan, Keson Beng Choon

    2018-02-01

    Prior studies have defined the accuracy of intraoral scanner (IOS) systems but the accuracy of the digital static interocclusal registration function of these systems has not been reported. This study compared the three-dimensional (3D) accuracy of the digital static interocclusal registration of 3 IOS systems using the buccal bite scan function. Three IOS systems compared were 3M TM True Definition Scanner (TDS), TRIOS Color (TRC), and CEREC AC with CEREC Omnicam (CER). Using each scanner, 7 scans (n = 7) of the mounted and articulated SLA master models were obtained. The measurement targets (SiN reference spheres and implant abutment analogs) were in the opposing models at the right (R), central (C), and left (L) regions; abutments #26 and #36, respectively. A coordinate measuring machine with metrology software compared the physical and virtual targets to derive the global 3D linear distortion between the centroids of the respective target reference spheres and abutment analogs (dR R , dR C , dR L , and dR M ) and 2D distances between the pierce points of the abutment analogs (dX M , dY M , dZ M ), with 3 measurement repetitions for each scan. Mean 3D distortion ranged from -471.9 to 31.7 μm for dR R , -579.0 to -87.0 μm for dR C , -381.5 to 69.4 μm for dR L , and -184.9 to -23.1 μm for dR M . Mean 2D distortion ranged from -225.9 to 0.8 μm for dX M , -130.6 to -126.1 μm for dY M , and -34.3 to 26.3 μm for dZ M . Significant differences were found for interarch distortions across the three systems. For dR R and dR L , all three test groups were significantly different, whereas for dR C , the TDS was significantly different from the TRC and CER. For 2D distortion, significant differences were found for dX M only. Interarch and global interocclusal distortions for the three IOS systems were significantly different. TRC performed overall the best and TDS was the worst. The interarch (dR R , dR C , dR L ) and interocclusal (dX M ) distortions observed will affect the magnitude of occlusal contacts of restorations clinically. The final restoration may be either hyperoccluded or infraoccluded, requiring compensations during the CAD design stage or clinical adjustments at issue. © 2017 by the American College of Prosthodontists.

  19. The Attitude Control System for the Wilkinson Microwave Anisotropy Probe

    NASA Technical Reports Server (NTRS)

    Markley, F. Landis; Andrews, Stephen F.; ODonnell, James R., Jr.; Ward, David K.

    2003-01-01

    The Wilkinson Microwave Anisotropy Probe mission produces a map of the cosmic microwave background radiation over the entire celestial sphere by executing a fast spin and a slow precession of its spin axis about the Sun line to obtain a highly interconnected set of measurements. The spacecraft attitude is sensed and controlled using an inertial reference unit, two star trackers, a digital sun sensor, twelve coarse sun sensors, three reaction wheel assemblies, and a propulsion system. Sufficient attitude knowledge is provided to yield instrument pointing to a standard deviation (l sigma) of 1.3 arc-minutes per axis. In addition, the spacecraft acquires and holds the sunline at initial acquisition and in the event of a failure, and slews to the proper orbit adjust orientations and to the proper off-sunline attitude to start the compound spin. This paper presents an overview of the design of the attitude control system to carry out this mission and presents some early flight experience.

  20. Computation of indirect nuclear spin-spin couplings with reduced complexity in pure and hybrid density functional approximations.

    PubMed

    Luenser, Arne; Kussmann, Jörg; Ochsenfeld, Christian

    2016-09-28

    We present a (sub)linear-scaling algorithm to determine indirect nuclear spin-spin coupling constants at the Hartree-Fock and Kohn-Sham density functional levels of theory. Employing efficient integral algorithms and sparse algebra routines, an overall (sub)linear scaling behavior can be obtained for systems with a non-vanishing HOMO-LUMO gap. Calculations on systems with over 1000 atoms and 20 000 basis functions illustrate the performance and accuracy of our reference implementation. Specifically, we demonstrate that linear algebra dominates the runtime of conventional algorithms for 10 000 basis functions and above. Attainable speedups of our method exceed 6 × in total runtime and 10 × in the linear algebra steps for the tested systems. Furthermore, a convergence study of spin-spin couplings of an aminopyrazole peptide upon inclusion of the water environment is presented: using the new method it is shown that large solvent spheres are necessary to converge spin-spin coupling values.

  1. Adsorption of Selenium and Strontium on Goethite: EXAFS Study and Surface Complexation Modeling of the Ternary Systems.

    PubMed

    Nie, Zhe; Finck, Nicolas; Heberling, Frank; Pruessmann, Tim; Liu, Chunli; Lützenkirchen, Johannes

    2017-04-04

    Knowledge of the geochemical behavior of selenium and strontium is critical for the safe disposal of radioactive wastes. Goethite, as one of the most thermodynamically stable and commonly occurring natural iron oxy-hydroxides, promisingly retains these elements. This work comprehensively studies the adsorption of Se(IV) and Sr(II) on goethite. Starting from electrokinetic measurements, the binary and ternary adsorption systems are investigated and systematically compared via batch experiments, EXAFS analysis, and CD-MUSIC modeling. Se(IV) forms bidentate inner-sphere surface complexes, while Sr(II) is assumed to form outer-sphere complexes at low and intermediate pH and inner-sphere complexes at high pH. Instead of a direct interaction between Se(IV) and Sr(II), our results indicate an electrostatically driven mutual enhancement of adsorption. Adsorption of Sr(II) is promoted by an average factor of 5 within the typical groundwater pH range from 6 to 8 for the concentration range studied here. However, the interaction between Se(IV) and Sr(II) at the surface is two-sided, Se(IV) promotes Sr(II) outer-sphere adsorption, but competes for inner-sphere adsorption sites at high pH. The complexity of surfaces is highlighted by the inability of adsorption models to predict isoelectric points without additional constraints.

  2. Satellite (Timed, Aura, Aqua) and In Situ (Meteorological Rockets, Balloons) Measurement Comparability

    NASA Technical Reports Server (NTRS)

    Schmidlin, F. J.; Goldberg, Richard A.; Feofilov, A.; Rose, R.

    2010-01-01

    Measurements using the inflatable falling sphere often are requested to provide density data in support of special sounding rocket launchings into the mesosphere and thermosphere. To insure density measurements within narrow time frames and close in space, the inflatable falling sphere is launched within minutes of the major test. Sphere measurements are reliable for the most part, however, availability of these rocket systems has become more difficult and, in fact, these instruments no longer are manufactured resulting in a reduction of the meager stockpile of instruments. Sphere measurements also are used to validate remotely measured temperatures and have the advantage of measuring small-scale atmospheric features. Even so, with the dearth of remaining falling spheres perhaps it is time to consider whether the remote measurements are mature enough to stand alone. Presented are two field studies, one in 2003 from Northern Sweden and one in 2010 from the vicinity of Kwajalein Atoll that compare temperature retrievals between satellite and in situ failing spheres. The major satellite instruments employed are SABER, MLS, and AIRS. The comparisons indicate that remotely measured temperatures mimic the sphere temperature measurements quite well. The data also confirm that satellite retrievals, while not always at the exact location required for individual studies, are adaptable enough and highly useful. Although the falling sphere will provide a measurement at a specific location and time, satellites only pass a given location daily or less often. This report reveals that averaged satellite measurements can provide temperatures and densities comparable to the falling sphere.

  3. A Sphere of Resonance for Networked Learning in the "Non-Places" of Our Universities

    ERIC Educational Resources Information Center

    Hayes, Sarah

    2015-01-01

    The logic of "time" in modern capitalist society appears to be a fixed concept. Time dictates human activity with a regularity, which as long ago as 1944, George Woodcock referred to as "The Tyranny of the Clock". Seventy years on, Hartmut Rosa suggests humans no longer maintain speed to achieve something new, but simply to…

  4. SPHERES as Formation Flight Algorithm Development and Validation Testbed: Current Progress and Beyond

    NASA Technical Reports Server (NTRS)

    Kong, Edmund M.; Saenz-Otero, Alvar; Nolet, Simon; Berkovitz, Dustin S.; Miller, David W.; Sell, Steve W.

    2004-01-01

    The MIT-SSL SPHERES testbed provides a facility for the development of algorithms necessary for the success of Distributed Satellite Systems (DSS). The initial development contemplated formation flight and docking control algorithms; SPHERES now supports the study of metrology, control, autonomy, artificial intelligence, and communications algorithms and their effects on DSS projects. To support this wide range of topics, the SPHERES design contemplated the need to support multiple researchers, as echoed from both the hardware and software designs. The SPHERES operational plan further facilitates the development of algorithms by multiple researchers, while the operational locations incrementally increase the ability of the tests to operate in a representative environment. In this paper, an overview of the SPHERES testbed is first presented. The SPHERES testbed serves as a model of the design philosophies that allow for the various researches being carried out on such a facility. The implementation of these philosophies are further highlighted in the three different programs that are currently scheduled for testing onboard the International Space Station (ISS) and three that are proposed for a re-flight mission: Mass Property Identification, Autonomous Rendezvous and Docking, TPF Multiple Spacecraft Formation Flight in the first flight and Precision Optical Pointing, Tethered Formation Flight and Mars Orbit Sample Retrieval for the re-flight mission.

  5. Core-Shell Particles as Building Blocks for Systems with High Duality Symmetry

    NASA Astrophysics Data System (ADS)

    Rahimzadegan, Aso; Rockstuhl, Carsten; Fernandez-Corbaton, Ivan

    2018-05-01

    Material electromagnetic duality symmetry requires a system to have equal electric and magnetic responses. Intrinsically dual materials that meet the duality conditions at the level of the constitutive relations do not exist in many frequency bands. Nevertheless, discrete objects like metallic helices and homogeneous dielectric spheres can be engineered to approximate the dual behavior. We exploit the extra degrees of freedom of a core-shell dielectric sphere in a particle optimization procedure. The duality symmetry of the resulting particle is more than 1 order of magnitude better than previously reported nonmagnetic objects. We use T -matrix-based multiscattering techniques to show that the improvement is transferred onto the duality symmetry of composite objects when the core-shell particle is used as a building block instead of homogeneous spheres. These results are relevant for the fashioning of systems with high duality symmetry, which are required for some technologically important effects.

  6. Extreme AO coronagraphy laboratory demonstration in the context of SPHERE

    NASA Astrophysics Data System (ADS)

    Martinez, P.; Aller Carpentier, E.; Kasper, M.

    2010-10-01

    The exoplanetary science through direct imaging and spectroscopy will largely expand with the very soon raise of new instruments at the VLT (SPHERE), Gemini (GPI), and Subaru (HiCIAO) observatories. All these ground-based adaptive optics instruments include extremely high performance adaptive optics (XAO) system, advanced starlight cancellation techniques (e.g. coronagraphy), and speckle calibration techniques (e.g. spectral, angular, or polarimetry). In this context we report laboratory results obtained with the High-Order Test bench (HOT), the adaptive optics facility at the European Southern Observatory headquarters. Under 0.5 arcsec dynamical seeing, efficiently corrected by an XAO system delivering H-band Strehl ratio above 90%, we discuss contrast levels obtained with an apodized pupil Lyot coronagraph using differential imaging techniques (spectral and polarimetric). Accounting for system differences (e.g. deformable mirror actuator number), we demonstrate a good agreement between experimental results and expectations for SPHERE, or GPI, while we already met HiCIAO contrast goals.

  7. Optical coupling of cold atoms to a levitated nanosphere

    NASA Astrophysics Data System (ADS)

    Montoya, Cris; Witherspoon, Apryl; Fausett, Jacob; Lim, Jason; Kitching, John; Geraci, Andrew

    2017-04-01

    Cooling mechanical oscillators to their quantum ground state enables the study of quantum phenomena at macroscopic levels. In many cases, the temperature required to cool a mechanical mode to the ground state is below what current cryogenic systems can achieve. As an alternative to cooling via cryogenic systems, it has been shown theoretically that optically trapped nanospheres could reach the ground state by sympathetically cooling the spheres via cold atoms. Such cooled spheres can be used in quantum limited sensing and matter-wave interferometry, and could also enable new hybrid quantum systems where mechanical oscillators act as transducers. In our setup, optical fields are used to couple a sample of cold Rubidium atoms to a nanosphere. The sphere is optically levitated in a separate vacuum chamber, while the atoms are trapped in a 1-D optical lattice and cooled using optical molasses. This work is partially supported by NSF, Grant No. PHY-1506431.

  8. Pattern formation in a monolayer of magnetic spheres

    NASA Astrophysics Data System (ADS)

    Stambaugh, Justin; Lathrop, Daniel P.; Ott, Edward; Losert, Wolfgang

    2003-08-01

    Pattern formation is investigated for a vertically vibrated monolayer of magnetic spheres. The spheres of diameter D encase cylindrical magnetic cores of length l. For large D/l, we find that the particles form a hexagonal-close-packed pattern in which the particles’ dipole vectors assume a macroscopic circulating vortical pattern. For smaller D/l, the particles form concentric rings. The static configurational magnetic energy (which depends on D/l) appears to be a determining factor in pattern selection even though the experimental system is driven and dissipative.

  9. Identification and onset of inertial modes in the wide-gap spherical Couette system

    NASA Astrophysics Data System (ADS)

    Barik, A.; Wicht, J.; Triana, S. A.; Hoff, M.

    2016-12-01

    The spherical Couette system consists of two concentric rotating spheres with a fluid filling the shell in between. The system has been studied for a long time by fluid dynamicists and is ideal for studying flow instabilities due to differential rotation and the interaction of the same with magnetic fields - important for understanding dynamics of planetary and stellar interiors. The system is also a basis for a new generation of dynamo experiments because of its closer geometrical resemblance to real astrophysical objects as compared to past experiments. We simulate this system using the two different pseudo-spectral codes MagIC and XSHELLS. We focus here on a very interesting and general instability in this system - inertial modes. A rotating body of fluid is known to sustain oscillatory waves due to the restoring action of the Coriolis force. In a bounded container, these form a discrete spectrum called inertial modes. These modes have been analytically known for a rotating full sphere for over a century now. In a spherical shell, they cannot be formulated analytically. However, many of these inertial modes are observed in spherical Couette experiments as well as in simulations. Past studies have tried to explain the onset of these modes invoking wave over-reflection or critical layer instabilities on the cylinder tangent to the inner sphere. In this study, we present the inertial modes found in our simulations and try to explain their onset as secondary instabilities due to the destabilization of the fundamental non-axisymmetric instability, forming a triadic resonance with the fundamental instability. We run various simulations varying the rotation rate of the inner sphere, while keeping the rotation rate of the outer sphere constant. We track velocities and induced magnetic field and produce spectrograms similar to those of the experiments. Our results match very well the experimental data from spherical Couette set-ups at BTU Cottbus and the University of Maryland.

  10. Spherical Magnetic Vortex in an External Potential Field: A Dissipative Contraction

    NASA Astrophysics Data System (ADS)

    Solov'ev, A. A.

    2013-09-01

    We consider the dissipative evolution of a spherical magnetic vortex with a force-free internal structure, located in a resistive medium and held in equilibrium by the potential external field. The magnetic field inside the sphere is force-free (the model of Chandrasekhar in Proc. Natl. Acad. Sci. 42, 1, 1956). Topologically, it is a set of magnetic toroids enclosed in spherical layers. A new exact MHD solution has been derived, describing a slow, uniform, radial compression of a magnetic spheroid under the pressure of an ambient field, when the plasma density and pressure are growing inside it. There is no dissipation in the potential field outside the sphere, but inside the sphere, where the current density can be high enough, the magnetic energy is continuously converted into heat. Joule dissipation lowers the magnetic pressure inside the sphere, which balances the pressure of the ambient field. This results in radial contraction of the magnetic sphere with a speed defined by the conductivity of the plasma and the characteristic spatial scale of the magnetic field inside the sphere. Formally, the sphere shrinks to zero within a finite time interval (magnetic collapse). The time of compression can be relatively small, within a day, even for a sphere with a radius of about 1 Mm, if the magnetic helicity trapped initially in the sphere (which is proportional to the number of magnetic toroids in the sphere) is quite large. The magnetic system is open along its axis of symmetry. On this axis, the magnetic and electric fields are strictly radial and sign-variable along the radius, so the plasma will be ejected along the axis of magnetic sphere outwards in both directions (as jets) at a rate much higher than the diffusive one, and the charged particles will be accelerated unevenly, in spurts, creating quasi-regular X-ray spikes. The applications of the solution to solar flares are discussed.

  11. Verification of micro-scale photogrammetry for smooth three-dimensional object measurement

    NASA Astrophysics Data System (ADS)

    Sims-Waterhouse, Danny; Piano, Samanta; Leach, Richard

    2017-05-01

    By using sub-millimetre laser speckle pattern projection we show that photogrammetry systems are able to measure smooth three-dimensional objects with surface height deviations less than 1 μm. The projection of laser speckle patterns allows correspondences on the surface of smooth spheres to be found, and as a result, verification artefacts with low surface height deviations were measured. A combination of VDI/VDE and ISO standards were also utilised to provide a complete verification method, and determine the quality parameters for the system under test. Using the proposed method applied to a photogrammetry system, a 5 mm radius sphere was measured with an expanded uncertainty of 8.5 μm for sizing errors, and 16.6 μm for form errors with a 95 % confidence interval. Sphere spacing lengths between 6 mm and 10 mm were also measured by the photogrammetry system, and were found to have expanded uncertainties of around 20 μm with a 95 % confidence interval.

  12. Potential Representation - Global vs. Local Trial Functions

    NASA Astrophysics Data System (ADS)

    Michel, Volker

    2014-05-01

    Many systems of trial functions are available for representing potential fields on the sphere or parts of the sphere. We distinguish global trial functions (such as spherical harmonics) from localized trial functions (such as spline basis functions, scaling functions, wavelets, and Slepian functions). All these systems have their own pros and cons. We discuss the advantages and disadvantages of several selected systems of trial functions and propose criteria for their applicability. Moreover, we present an algorithm which is able to combine different types of trial functions. This yields a sparser solution which combines the features of the different basis systems which are used.

  13. Fluorescent/magnetic micro/nano-spheres based on quantum dots and/or magnetic nanoparticles: preparation, properties, and their applications in cancer studies

    NASA Astrophysics Data System (ADS)

    Wen, Cong-Ying; Xie, Hai-Yan; Zhang, Zhi-Ling; Wu, Ling-Ling; Hu, Jiao; Tang, Man; Wu, Min; Pang, Dai-Wen

    2016-06-01

    The study of cancer is of great significance to human survival and development, due to the fact that cancer has become one of the greatest threats to human health. In recent years, the rapid progress of nanoscience and nanotechnology has brought new and bright opportunities to this field. In particular, the applications of quantum dots (QDs) and magnetic nanoparticles (MNPs) have greatly promoted early diagnosis and effective therapy of cancer. In this review, we focus on fluorescent/magnetic micro/nano-spheres based on QDs and/or MNPs (we may call them ``nanoparticle-sphere (NP-sphere) composites'') from their preparation to their bio-application in cancer research. Firstly, we outline and compare the main four kinds of methods for fabricating NP-sphere composites, including their design principles, operation processes, and characteristics (merits and limitations). The NP-sphere composites successfully inherit the unique fluorescence or magnetic properties of QDs or MNPs. Moreover, compared with the nanoparticles (NPs) alone, the NP-sphere composites show superior properties, which are also discussed in this review. Then, we summarize their recent applications in cancer research from three aspects, that is: separation and enrichment of target tumor cells or biomarkers; cancer diagnosis mainly through medical imaging or tumor biomarker detection; and cancer therapy via targeted drug delivery systems. Finally, we provide some perspectives on the future challenges and development trends of the NP-sphere composites.

  14. Anionic surfactants templating route for synthesizing silica hollow spheres with different shell porosity

    NASA Astrophysics Data System (ADS)

    Han, Lu; Gao, Chuanbo; Wu, Xiaowei; Chen, Qianru; Shu, Peng; Ding, Zhiguang; Che, Shunai

    2011-04-01

    Silica hollow spheres with different shell porosity were simply synthesized with micelle and emulsion dual templating route. Various anionic surfactants, such as palmitic acid (C 16AA), N-acyl- L-phenylalanine (C 18Phe), N-palmitoyl- L-alanine (C 16AlaA) and oleic acid (OA) have been used as templates, and 3-aminopropyl-triethoxysilane (APES) and tetraethyl orthosilicate (TEOS) have been used as co-structure directing agent (CSDA) and silica source, respectively. The circle lamellar layer structure and mesopores vertical to the silica hollow spheres surface are believed to originate from the initial formation of amphiphilic carboxylic acid oil drop, which afterwards self-assemble to form the shell of hollow spheres and its mesostructure upon addition of CSDA and silica source. The mesoporous silica hollow spheres with high porosity could be achieved by adding a moderate amount of ethanol in the OA synthesis system, depending on the co-surfactant effect of ethanol that changes the curvature of micelles. The particle diameter and the hollow structure have been controlled by choosing different templates and by manipulating synthesis gel composition. The average particle diameter of the mesoporous silica hollow spheres were controlled in the range of 80-220 nm with constant shell thickness of ˜20 nm and constant mesopore size of ˜4 nm. Besides, the formation of the silica hollow spheres has been investigated in detail with reaction time. These mesoporous silica hollow spheres would have potential applications on catalysis, bimolecular encapsulation, adsorption, drug release, etc.

  15. Two-Phase Flow and Compaction Within and Outside a Sphere under Pure Shear

    NASA Astrophysics Data System (ADS)

    Hier-Majumder, S.

    2017-12-01

    This work presents a framework for building analytical solutions for coupled flow in two interacting multiphase domains. The coupled system consists of a multiphase sphere embedded in a multiphase substrate. Each of these domains consist of an interconnected load bearing matrix phase and an inviscid interstitial fluid phase. This work outlines techniques for building analytical solutions for velocity, pressure, and compaction within each domain, subject to boundary conditions of continuity of matrix velocity and normal traction at the interface between the two domains. The solutions indicate that the flow is strongly dependent on the ratio of shear viscosities between the matrix phase in the sphere and the matrix phase in the substrate. When deformed under a pure shear deformation, the magnitude of flow within the sphere rapidly decreases with an increase in this ratio until it reaches a value of 40, after which, the velocity within the sphere becomes relatively insensitive to the increase in the viscosity contrast.

  16. Close packing in curved space by simulated annealing

    NASA Astrophysics Data System (ADS)

    Wille, L. T.

    1987-12-01

    The problem of packing spheres of a maximum radius on the surface of a four-dimensional hypersphere is considered. It is shown how near-optimal solutions can be obtained by packing soft spheres, modelled as classical particles interacting under an inverse power potential, followed by a subsequent hardening of the interaction. In order to avoid trapping in high-lying local minima, the simulated annealing method is used to optimise the soft-sphere packing. Several improvements over other work (based on local optimisation of random initial configurations of hard spheres) have been found. The freezing behaviour of this system is discussed as a function of particle number, softness of the potential and cooling rate. Apart from their geometric interest, these results are useful in the study of topological frustration, metallic glasses and quasicrystals.

  17. A new potential for the numerical simulations of electrolyte solutions on a hypersphere

    NASA Astrophysics Data System (ADS)

    Caillol, Jean-Michel

    1993-12-01

    We propose a new way of performing numerical simulations of the restricted primitive model of electrolytes—and related models—on a hypersphere. In this new approach, the system is viewed as a single component fluid of charged bihard spheres constrained to move at the surface of a four dimensional sphere. A charged bihard sphere is defined as the rigid association of two antipodal charged hard spheres of opposite signs. These objects interact via a simple analytical potential obtained by solving the Poisson-Laplace equation on the hypersphere. This new technique of simulation enables a precise determination of the chemical potential of the charged species in the canonical ensemble by a straightforward application of Widom's insertion method. Comparisons with previous simulations demonstrate the efficiency and the reliability of the method.

  18. A mesh-free approach to acoustic scattering from multiple spheres nested inside a large sphere by using diagonal translation operators.

    PubMed

    Hesford, Andrew J; Astheimer, Jeffrey P; Greengard, Leslie F; Waag, Robert C

    2010-02-01

    A multiple-scattering approach is presented to compute the solution of the Helmholtz equation when a number of spherical scatterers are nested in the interior of an acoustically large enclosing sphere. The solution is represented in terms of partial-wave expansions, and a linear system of equations is derived to enforce continuity of pressure and normal particle velocity across all material interfaces. This approach yields high-order accuracy and avoids some of the difficulties encountered when using integral equations that apply to surfaces of arbitrary shape. Calculations are accelerated by using diagonal translation operators to compute the interactions between spheres when the operators are numerically stable. Numerical results are presented to demonstrate the accuracy and efficiency of the method.

  19. A mesh-free approach to acoustic scattering from multiple spheres nested inside a large sphere by using diagonal translation operators

    PubMed Central

    Hesford, Andrew J.; Astheimer, Jeffrey P.; Greengard, Leslie F.; Waag, Robert C.

    2010-01-01

    A multiple-scattering approach is presented to compute the solution of the Helmholtz equation when a number of spherical scatterers are nested in the interior of an acoustically large enclosing sphere. The solution is represented in terms of partial-wave expansions, and a linear system of equations is derived to enforce continuity of pressure and normal particle velocity across all material interfaces. This approach yields high-order accuracy and avoids some of the difficulties encountered when using integral equations that apply to surfaces of arbitrary shape. Calculations are accelerated by using diagonal translation operators to compute the interactions between spheres when the operators are numerically stable. Numerical results are presented to demonstrate the accuracy and efficiency of the method. PMID:20136208

  20. orbis (sphaera), circulus, via, iter, orbita -- on the terminological identification of the essential paradigm change in astronomy by Johannes Kepler. (German Title: orbis (sphaera), circulus, via, iter, orbita} -- zur terminologischen Kennzeichnung des wesentlichsten Paradigmawechsels in der Astronomie durch Johannes Kepler)

    NASA Astrophysics Data System (ADS)

    Krafft, Fritz

    2011-08-01

    The use of modern terminology hinders to understand historical astronomical texts and often misleads the reader. Therefore, this study tries to reconstruct the ideas of the way the planets seem to move against the sphere of fixed stars in a non-teleological manner, that means in the original view and with original terms. The study proceeds historically and explains: (1) Aristotle's system of homocentric spheres being hollow spheres of ether turning equally round the earth in the centre of the world, a number of which makes the apparatus of the movement of a planet which produces its apparently unequal motion. (2) Ptolemy's reductionistic system of geometric circles (eccentric deferents, epicycles etc.), which are indeed great circles on non-concentric hollow spheres, whereupon they turn around equally. The space which they take up in all is surrounded by an inner and an outer concentric spherical surface and makes the sphere of the planet. (3) John's of Sacrobosco transferring of the geometric astronomy to the Latin of Middle Ages and the commentators' precision of the Greek-Latin terms. (4) The tradition of the "Theorica planetarum" which makes this geometry physics by allotting every partial moving to a partial material hollow sphere (with spherical surfaces of different centricity) or full sphere of an epicycle (orbes particulares or partialis), a number of which makes the entire sphere of each planet (orbis totalis or totus). - Copernicus also stood within this tradition, except that his entire spheres differ from the earlier ones in size or thickness (because he eliminated the partly very big synodic epicycles and allocated their effect as a mere parallactic one to the yearly moving of the earth) and in the great intervening spaces between each other (a result of measuring the true distances of the planets on the basis of these parallactic effects). (5) Tycho Brahe's refutation of the unchangingness and unpermeableness and therefore solidity of all etherial spheres, what had been the fundamental condition for creating the indirect ways of the planets in all astronomical systems with partial or entire spheres engaging one another. It was particularly Kepler who recognizes that as a result celestial physics requires a complete change. (6) Kepler's replacement of celestial physics. He did not think any more that the apparent (unequal) way of a planet indirectly results from the combination of several equal movements of etherial partial and entire spheres. His planets move their true and real way caused directly by the joint effect of two corporal forces moving the planets both around the sun and to and from it, which latter makes the planet's speed indeed naturally unequal. For this "real way" he coins in late 1604 the specific term "orbita" (the modern "orbit", the German "Bahn". This term then little by little replaced the former non-specific, general description of the apparent or real way (as "via, iter, ambitus, circulus, circuitus" etc.), and Kepler used it increasingly from its introduction (initially frequently joined to a describing definition of this "way") up to the exclusive use in the fifth book of the "Epitome", after this "orbita" had changed its shape from a perfect eccentric circle to an oval and finally an elliptic form. This way Kepler marks the paradigm change of astronomy caused by himself also terminologically.

  1. Liquid crystalline phase behavior in systems of hard-sphere chains

    NASA Astrophysics Data System (ADS)

    Williamson, Dave C.; Jackson, George

    1998-06-01

    A study of the liquid crystalline phase transitions in a system of hard-sphere chains is presented. The chains comprise m=7 tangentially bonded hard-sphere segments in a linear conformation (LHSC). The isothermal-isobaric Monte Carlo simulation technique is used to obtain the equation of state of the system both by compressing the isotropic (I) liquid and by expanding the solid (K). As well as the usual isotropic and solid phases, nematic and smectic-A liquid crystalline states are seen. A large degree of hysteresis is found in the neighborhood of the I-N transition. The results for the rigid LHSC system were compared with existing data for the corresponding semiflexible hard-sphere chains (FHSC): the flexibility has a large destabilizing effect on the nematic phase and consequently it postpones the I-N transition. The results of the simulations are also compared with rescaled Onsager theories for the I-N transition. It is rather surprising to find that the Parsons approach, which has been so successful for other hard-core models such as spherocylinders and ellipsoids, gives very poor results. The related approach of Vega and Lago gives a good description of the I-N phase transition. The procedure of Vega and Lago, as with all two-body resummations of the Onsager theory, only gives a qualitative description of the nematic order.

  2. Thermal compatibility of dental ceramic systems using cylindrical and spherical geometries.

    PubMed

    DeHoff, Paul H; Barrett, Allyson A; Lee, Robert B; Anusavice, Kenneth J

    2008-06-01

    To test the hypothesis that bilayer ceramic cylinders and spheres can provide valid confirmation of thermal incompatibility stresses predicted by finite element analyses. A commercial core ceramic and an experimental core ceramic were used to fabricate open-ended cylinders and core ceramic spheres. The core cylinders and spheres were veneered with one of four commercial dental ceramics representing four thermally compatible groups and four thermally incompatible groups. Axisymmetric thermal and viscoelastic elements in the ANSYS finite element program were used to calculate temperatures and stresses for each geometry and ceramic combination. This process required a transient heat transfer analysis for each combination to determine input temperatures for the structural model. After fabrication, each specimen was examined visually using fiberoptic transillumination for evidence of cracking. There were 100% failures of the thermally incompatible cylinders while none of the thermally compatible combinations failed. Among the spheres, 100% of the thermally incompatible systems failed, 16% of one of the thermally compatible systems failed, and none of the remaining compatible combinations failed. The calculated stress values were in general agreement with the experimental observations, i.e., low residual stresses for the specimens that did not fail and high residual stresses for the specimens that did fail. Simple screening geometries can be used to identify highly incompatible ceramic combinations, but they do not identify marginally incompatible systems.

  3. Thermal compatibility of dental ceramic systems using cylindrical and spherical geometries

    PubMed Central

    DeHoff, Paul H.; Barrett, Allyson A.; Lee, Robert B.; Anusavice, Kenneth J.

    2009-01-01

    Objective To test the hypothesis that bilayer ceramic cylinders and spheres can provide valid confirmation of thermal incompatibility stresses predicted by finite element analyses. Methods A commercial core ceramic and an experimental core ceramic were used to fabricate open-ended cylinders and core ceramic spheres. The core cylinders and spheres were veneered with one of four commercial dental ceramics representing four thermally compatible groups and four thermally incompatible groups. Axisymmetric thermal and viscoelastic elements in the ANSYS finite element program were used to calculate temperatures and stresses for each geometry and ceramic combination. This process required a transient heat transfer analysis for each combination to determine input temperatures for the structural model. Results After fabrication, each specimen was examined visually using fiberoptic transillumination for evidence of cracking. There were 100% failures of the thermally incompatible cylinders while none of the thermally compatible combinations failed. Among the spheres, 100% of the thermally incompatible systems failed, 16% of one of the thermally compatible systems failed, and none of the remaining compatible combinations failed. The calculated stress values were in general agreement with the experimental observations, i.e., low residual stresses for the specimens that did not fail and high residual stresses for the specimens that did fail. Significance Simple screening geometries can be used to identify highly incompatible ceramic combinations, but they do not identify marginally incompatible systems. PMID:17949805

  4. Probing the young circumplanetary environment of Beta Pic b during transit egress

    NASA Astrophysics Data System (ADS)

    Wang, Jason

    2017-08-01

    Among the thousands of known exoplanets, Beta Pic b is the only directly imaged exoplanet with a nearly edge-on orbit. We show that the latest astrometric measurements rule out a transit by the planet at 10-sigma significance, but we are certain that the Hill sphere of the planet will transit. With a period of 22 years and no other system like it, this Hill sphere transit provides a rare opportunity to study the evolving circumplanetary environment of a young and well-characterized exoplanet. To compliment GO-14621, our Cycle 25 proposal to monitor the ingress of the Hill sphere, we propose a modest HST program to photometrically search for signatures of the planet's large scale circumplanetary material during the egress of the Hill sphere transit. The existence of such material is plausible given that Beta Pic's young age is similar to that of the ring-bearing J1407b system. Combined with GO-14621 and less-precise but dedicated ground-based monitoring, these observations will give us a comprehensive set of observations about this young circumplanetary environment. Given the sparse observational data of circumplanetary environments, non-detections will also be valuable for constraining the timescales relevant to circumplanetary material and moon formation. If photometric variations are detected with HST, these results would yield empirical information concerning the dynamics of the system and the evolution of planetary systems as a whole.

  5. Goddard Queen Visit

    NASA Image and Video Library

    2007-05-07

    Queen Elizabeth II and Prince Philip, The Duke of Edinburgh look on as Goddard employees demonstrate “Science on a Sphere.” This system, developed by the National Oceanic and Atmospheric Administration (NOAA), uses computers and four video projectors to display animated images on the outside of a 6-foot diameter sphere. Photo Credit: (NASA/Pat Izzo)

  6. Note: equation of state and the freezing point in the hard-sphere model.

    PubMed

    Robles, Miguel; López de Haro, Mariano; Santos, Andrés

    2014-04-07

    The merits of different analytical equations of state for the hard-sphere system with respect to the recently computed high-accuracy value of the freezing-point packing fraction are assessed. It is found that the Carnahan-Starling-Kolafa and the branch-point approximant equations of state yield the best performance.

  7. A new dipolar potential for numerical simulations of polar fluids on the 4D hypersphere

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Caillol, Jean-Michel, E-mail: Jean-Michel.Caillol@th.u-psud.fr; Trulsson, Martin, E-mail: martin.trulsson@lptms.u-psud.fr

    2014-09-28

    We present a new method for Monte Carlo or Molecular Dynamics numerical simulations of three-dimensional polar fluids. The simulation cell is defined to be the surface of the northern hemisphere of a four-dimensional (hyper)sphere. The point dipoles are constrained to remain tangent to the sphere and their interactions are derived from the basic laws of electrostatics in this geometry. The dipole-dipole potential has two singularities which correspond to the following boundary conditions: when a dipole leaves the northern hemisphere at some point of the equator, it reappears at the antipodal point bearing the same dipole moment. We derive all themore » formal expressions needed to obtain the thermodynamic and structural properties of a polar liquid at thermal equilibrium in actual numerical simulation. We notably establish the expression of the static dielectric constant of the fluid as well as the behavior of the pair correlation at large distances. We report and discuss the results of extensive numerical Monte Carlo simulations for two reference states of a fluid of dipolar hard spheres and compare these results with previous methods with a special emphasis on finite size effects.« less

  8. A new dipolar potential for numerical simulations of polar fluids on the 4D hypersphere

    NASA Astrophysics Data System (ADS)

    Caillol, Jean-Michel; Trulsson, Martin

    2014-09-01

    We present a new method for Monte Carlo or Molecular Dynamics numerical simulations of three-dimensional polar fluids. The simulation cell is defined to be the surface of the northern hemisphere of a four-dimensional (hyper)sphere. The point dipoles are constrained to remain tangent to the sphere and their interactions are derived from the basic laws of electrostatics in this geometry. The dipole-dipole potential has two singularities which correspond to the following boundary conditions: when a dipole leaves the northern hemisphere at some point of the equator, it reappears at the antipodal point bearing the same dipole moment. We derive all the formal expressions needed to obtain the thermodynamic and structural properties of a polar liquid at thermal equilibrium in actual numerical simulation. We notably establish the expression of the static dielectric constant of the fluid as well as the behavior of the pair correlation at large distances. We report and discuss the results of extensive numerical Monte Carlo simulations for two reference states of a fluid of dipolar hard spheres and compare these results with previous methods with a special emphasis on finite size effects.

  9. Simple effective rule to estimate the jamming packing fraction of polydisperse hard spheres.

    PubMed

    Santos, Andrés; Yuste, Santos B; López de Haro, Mariano; Odriozola, Gerardo; Ogarko, Vitaliy

    2014-04-01

    A recent proposal in which the equation of state of a polydisperse hard-sphere mixture is mapped onto that of the one-component fluid is extrapolated beyond the freezing point to estimate the jamming packing fraction ϕJ of the polydisperse system as a simple function of M1M3/M22, where Mk is the kth moment of the size distribution. An analysis of experimental and simulation data of ϕJ for a large number of different mixtures shows a remarkable general agreement with the theoretical estimate. To give extra support to the procedure, simulation data for seventeen mixtures in the high-density region are used to infer the equation of state of the pure hard-sphere system in the metastable region. An excellent collapse of the inferred curves up to the glass transition and a significant narrowing of the different out-of-equilibrium glass branches all the way to jamming are observed. Thus, the present approach provides an extremely simple criterion to unify in a common framework and to give coherence to data coming from very different polydisperse hard-sphere mixtures.

  10. Measurement and Evaluation of Quantitative Performance of PET/CT Images before a Multicenter Clinical Trial.

    PubMed

    Zhu, Yanjia; Geng, Caizheng; Huang, Jia; Liu, Juzhen; Wu, Ning; Xin, Jun; Xu, Hao; Yu, Lijuan; Geng, Jianhua

    2018-06-13

    To ensure the reliability of the planned multi-center clinical trial, we assessed the consistence and comparability of the quantitative parameters of the eight PET/CT units that will be used in this trial. PET/CT images were scanned using a PET NEMA image quality phantom (Biodex) on the eight units of Discovery PET/CT 690 from GE Healthcare. The scanning parameters were the same with the ones to be used in the planned trial. The 18 F-NaF concentration in the background was 5.3 kBq/ml, while the ones in the spheres of diameter 37 mm, 22 mm, 17 mm and 10 mm were 8:1 as to that of the background and the ones in the spheres of diameter 28 mm and 13 mm were 0 kBq/ml. The consistency of hot sphere recovery coefficient (HRC), cold sphere recovery coefficient (CRC), hot sphere contrast (Q H ) and cold sphere contrast (Q c ) among these 8 PET/CTs was analyzed. The variation of the main quantitative parameters of the eight PET/CT systems was within 10%, which is acceptable for the clinical trial.

  11. Enrichment and characterization of cancer stem cells from a human non-small cell lung cancer cell line.

    PubMed

    Zhao, Changhong; Setrerrahmane, Sarra; Xu, Hanmei

    2015-10-01

    Tumor cells from the same origin comprise different cell populations. Among them, cancer stem cells (CSCs) have higher tumorigenicity. It is necessary to enrich CSCs to determine an effective way to suppress and eliminate them. In the present study, using the non-adhesive culture system, tumor spheres were successfully generated from human A549 non-small cell lung cancer (NSCLC) cell line within 2 weeks. Compared to A549 adherent cells, sphere cells had a higher self-renewal ability and increased resistance to cytotoxic drugs. Sphere cells were more invasive and expressed stem cell markers including octamer‑binding transcription factor 4 (Oct4) and sex-determining region Y-box 2 (Sox2) at high levels. CD133, a disputed marker of lung CSCs, was also upregulated. Tumor sphere cells showed higher tumorigenic ability in vivo, indicating that more CSCs were enriched in the sphere cells. More blood vessels were formed in the tumor generated by sphere cells suggesting the interaction between CSCs and blood vessel. A reliable model of enriching CSCs from the human A549 NSCLC cell line was established that was simple and cost-effective compared to other methods.

  12. [STRESS DUE TO THE WORK-LIFE CONFLICT: ADVICES FROM APPLIED RESEARCH FOR COPING IT].

    PubMed

    Poerio, Vincenzo

    2015-01-01

    Unlike most of the work-related stress research, which emphasizes how to manage stressors and maximize the psychological well-being, the present article focuses on one particular kind of stressor: the experience of conflict or interference between demands at work and responsibilities and commitments outside of the work setting, especially in respect offamily life and one's personal life. Referred to as "work-family conflict" or (more recently) "work-life conflict", this stressor has been demonstrated in research since the 1990s to exert a considerable impact on individuals' well-being along with other areas such as family functioning and even performance on the job. In contrast to the intra-role conflict, which refers to interference between roles within a single domain (e.g., the work context), work-family (or work-life) conflict is a form of inter-role interference which occurs when there is conflict across domains. In the 1980s and 1990s, research and writing in this area focused predominantly on work versus family, but in recent years the "non-work" component has been expanded to include other aspects of people's lives. For simplicity, we will refer to the two major spheres as the "work domain" (i.e., a person's paid employment) and the "life domain" (which comprises all other dimensions of life, including family, recreation, community activities and personal life). Although this classification is not entirely appropriate, it enables differentiation between the two spheres.

  13. Corrected body surface potential mapping.

    PubMed

    Krenzke, Gerhard; Kindt, Carsten; Hetzer, Roland

    2007-02-01

    In the method for body surface potential mapping described here, the influence of thorax shape on measured ECG values is corrected. The distances of the ECG electrodes from the electrical heart midpoint are determined using a special device for ECG recording. These distances are used to correct the ECG values as if they had been measured on the surface of a sphere with a radius of 10 cm with its midpoint localized at the electrical heart midpoint. The equipotential lines of the electrical heart field are represented on the virtual surface of such a sphere. It is demonstrated that the character of a dipole field is better represented if the influence of the thorax shape is reduced. The site of the virtual reference electrode is also important for the dipole character of the representation of the electrical heart field.

  14. Dimensional accuracy of jaw scans performed on alginate impressions or stone models: A practice-oriented study.

    PubMed

    Vogel, Annike B; Kilic, Fatih; Schmidt, Falko; Rübel, Sebastian; Lapatki, Bernd G

    2015-07-01

    Digital jaw models offer more extensive possibilities for analysis than casts and make it easier to share and archive relevant information. The aim of this study was to compare the dimensional accuracy of scans performed on alginate impressions and on stone models to reference scans performed on underlying resin models. Precision spheres 5 mm in diameter were occlusally fitted to the sites of the first premolars and first molars on a pair of jaw models fabricated from resin. A structured-light scanner was used for digitization. Once the two reference models had been scanned, alginate impressions were taken and scanned after no later than 1 h. A third series of scans was performed on type III stone models derived from the impressions. All scans were analyzed by performing five repeated measurements to determine the distances between the various sphere centers. Compared to the reference scans, the stone-model scans were larger by a mean of 73.6 µm (maxilla) or 65.2 µm (mandible). The impression scans were only larger by 7.7 µm (maxilla) or smaller by 0.7 µm (mandible). Median standard deviations over the five repeated measurements of 1.0 µm for the reference scans, 2.35 µm for the impression scans, and 2.0 µm for the stone-model scans indicate that the values measured in this study were adequately reproducible. Alginate impressions can be suitably digitized by structured-light scanning and offer considerably better dimensional accuracy than stone models. Apparently, however, both impression scans and stone-model scans can offer adequate precision for orthodontic purposes. The main issue of impression scans (which is incomplete representation of model surfaces) is being systematically explored in a follow-up study.

  15. Structure factor of liquid alkali metals using a classical-plasma reference system

    NASA Astrophysics Data System (ADS)

    Pastore, G.; Tosi, M. P.

    1984-06-01

    This paper presents calculations of the liquid structure factor of the alkali metals near freezing, starting from the classical plasma of bare ions as reference liquid. The indirect ion-ion interaction arising from electronic screening is treated by an optimized random phase approximation (ORPA), imposing physical requirements as in the original ORPA scheme developed by Weeks, Chandler and Andersen for liquids with strongly repulsive core potentials. A comparison of the results with computer simulation data for a model of liquid rubidium shows that the present approach overcomes the well-known difficulties met in applying to these metals the standard ORPA based on a reference liquid of neutral hard spheres. The optimization scheme is also shown to be equivalent to a reduction of the range of the indirect interaction in momentum space, as proposed empirically in an earlier work. Comparison with experiment for the other alkalis shows that a good overall representation of the data can be obtained for sodium, potassium and cesium, but not for lithium, when one uses a very simple form of the electron-ion potential adjusted to the liquid compressibility. The small-angle scattering region is finally examined more carefully in the light of recent data of Waseda, with a view to possible refinements of the pseudopotential model.

  16. Radiometric Measurement Comparisons Using Transfer Radiometers in Support of the Calibration of NASA's Earth Observing System (EOS) Sensors

    NASA Technical Reports Server (NTRS)

    Butler, James J.; Johnson, B. Carol; Brown, Steven W.; Yoon, Howard W.; Barnes, Robert A.; Markham, Brian L.; Biggar, Stuart F.; Zalewski, Edward F.; Spyak, Paul R.; Cooper, John W.; hide

    1999-01-01

    EOS satellite instruments operating in the visible through the shortwave infrared wavelength regions (from 0.4 micrometers to 2.5 micrometers) are calibrated prior to flight for radiance response using integrating spheres at a number of instrument builder facilities. The traceability of the radiance produced by these spheres with respect to international standards is the responsibility of the instrument builder, and different calibration techniques are employed by those builders. The National Aeronautics and Space Administration's (NASA's) Earth Observing System (EOS) Project Science Office, realizing the importance of preflight calibration and cross-calibration, has sponsored a number of radiometric measurement comparisons, the main purpose of which is to validate the radiometric scale assigned to the integrating spheres by the instrument builders. This paper describes the radiometric measurement comparisons, the use of stable transfer radiometers to perform the measurements, and the measurement approaches and protocols used to validate integrating sphere radiances. Stable transfer radiometers from the National Institute of Standards and Technology, the University of Arizona Optical Sciences Center Remote Sensing Group, NASA's Goddard Space Flight Center, and the National Research Laboratory of Metrology in Japan, have participated in these comparisons. The approaches used in the comparisons include the measurement of multiple integrating sphere lamp levels, repeat measurements of select lamp levels, the use of the stable radiometers as external sphere monitors, and the rapid reporting of measurement results. Results from several comparisons are presented. The absolute radiometric calibration standard uncertainties required by the EOS satellite instruments are typically in the +/- 3% to +/- 5% range. Preliminary results reported during eleven radiometric measurement comparisons held between February 1995 and May 1998 have shown the radiance of integrating spheres agreed to within +/- 2.5% from the average at blue wavelengths and to within +/- 1.7% from the average at red and near infrared wavelengths. This level of agreement lends confidence in the use of the transfer radiometers in validating the radiance scales assigned by EOS instrument calibration facilities to their integrating sphere sources.

  17. Ellipsoids beat Spheres: Experiments with Candies, Colloids and Crystals

    NASA Astrophysics Data System (ADS)

    Chaikin, Paul

    2006-04-01

    How many gumballs fit in the glass sphere of a gumball machine? Scientists have been puzzling over problems like this since the Ancient Greeks. Yet it was only recently proven that the standard way of stacking oranges at a grocery store--with one orange on top of each set of three below--is the densist packing for spheres, with a packing fraction φ˜ 0.74. Random (amorphous) packings of spheres have a lower density, with φ ˜0.64. The density of crystalline and random packings of atoms is intimately related to the melting transition in matter. We have studied the crystal-liquid transition in spherical colloidal systems on earth and in microgravity. The simplest objects to study after spheres are squashed spheres -- ellipsoids. Surprisingly we find that ellipsoids can randomly pack more densely than spheres, up to φ˜0.68 - 0.71 for a shape close to that of M&M's^ Candies, and even approach φ˜0.75 for general ellipsoids. The higher density relates directly to the higher number of neighbors needed to prevent the more asymetric ellipsoid from rotating. We have also found the ellipsoids can be packed in a crystalline array to a density, φ˜.7707 which exceeds the highest previous packing. Our findings provide insights into granular materials, rigidity, crystals and glasses, and they may lead to higher quality ceramic materials.

  18. Spatially-Resolved Observations of Giant Stars with SPHERE

    NASA Astrophysics Data System (ADS)

    Khouri, Theo

    2018-04-01

    SPHERE on the VLT is an extreme adaptive optics instrument that produces images with unprecedented angular resolution at visible and near-infrared wavelengths. Its primary goal is imaging, low-resolution spectroscopic, and polarimetric characterization of extra-solar planetary systems. Nonetheless, the high spatial resolution and the instrument design optimized for observations in a narrow field of view around bright targets make SPHERE the perfect instrument for obtaining spatially-resolved images of close-by giant, evolved stars. This is particularly true at the shortest wavelengths available with SPHERE, where the angular resolution is best (> 20 mas) and these stars appear larger (< 70 mas). In this talk, I will review how SPHERE has been used to study the surfaces and extended atmospheres of evolved stars and how these observations advance our understanding of the stellar pulsations and convective motions that shape these stars. Moreover, I will present recent results from a monitoring campaign of the star R Doradus using SPHERE with observations taken at twelve epochs over eight months that reveal features on the stellar disc varying on timescales of a few weeks. Finally, I will present quasi-simultaneous observations with SPHERE and ALMA that spatially resolve the stellar discs of two asymptotic giant branch stars, Mira and R Doradus, and discuss what such multi-wavelength observation campaigns can teach us about the processes that shape evolved stars.

  19. Simulation and optimization of volume holographic imaging systems in Zemax.

    PubMed

    Wissmann, Patrick; Oh, Se Baek; Barbastathis, George

    2008-05-12

    We present a new methodology for ray-tracing analysis of volume holographic imaging (VHI) systems. Using the k-sphere formulation, we apply geometrical relationships to describe the volumetric diffraction effects imposed on rays passing through a volume hologram. We explain the k-sphere formulation in conjunction with ray tracing process and describe its implementation in a Zemax UDS (User Defined Surface). We conclude with examples of simulation and optimization results and show proof of consistency and usefulness of the proposed model.

  20. Improved integrating-sphere throughput with a lens and nonimaging concentrator.

    PubMed

    Chenault, D B; Snail, K A; Hanssen, L M

    1995-12-01

    A reflectometer design utilizing an integrating sphere with a lens and nonimaging concentrator is described. Compared with previous designs where a collimator was used to restrict the detector field of view, the concentrator-lens combination significantly increases the throughput of the reflectometer. A procedure for designing lens-concentrators is given along with the results of parametric studies. The measured angular response of a lens-concentrator system is compared with ray-trace predictions and with the response of an ideal system.

  1. Bufalin inhibits the differentiation and proliferation of human osteosarcoma cell line hMG63-derived cancer stem cells.

    PubMed

    Chang, Yuewen; Zhao, Yongfang; Zhan, Hongsheng; Wei, Xiaoen; Liu, Tianjin; Zheng, Bo

    2014-02-01

    Cancer stem cells (CSCs) play an important role in drug resistance of tumor and are responsible for high recurrence rates. Agents that can suppress the proliferation and differentiation of CSCs would provide new opportunity to fight against tumor recurrence. In this study, we developed a new strategy to enrich CSCs in human osteosarcoma cell line hMG63. Using these CSCs as model, we tested the effect of bufalin, a traditional Chinese medicine, on the proliferation and differentiation of CSCs. hMG63 cells were cultured in poly-HEMA-treated dish and cancer stem cell-specific medium. In this nonadhesive culture system, hMG63 formed spheres, which were then collected and injected into the immunodeficient mice. Cisplatin was administered every 3 days for five times. The enriched xenograft tumors were cultured in cancer stem cell-specific medium again to form tumor spheres. Expression of cancer stem cell markers of these cells was measured by flow cytometry. These cells were then treated with bufalin, and the proliferation and differentiation ability were indicated by the expression level of molecular markers and the formation of sphere again in vitro. We obtained a low CD133+/CD44 cell population with high-level stem cell marker. When treated with bufalin, the sphere could not get attached to the flask and failed to differentiate, which was indicated by the stable expression of stem cell marker CD133 and OCT-4 in the condition permissive to differentiation. Treatment of bufalin also suppressed the single cells isolated from the sphere to form sphere again in the nonadhesive culture system, and a decreased expression of proliferation marker Ki67 was also detected in these cells. Sphere-formed and chemoresistant colon xenograft tumors in immunodeficient mice could enrich cancer stem cell population. Bufalin could inhibit proliferation and differentiation of CSCs.

  2. A ocean bottom vector magnetometer

    NASA Astrophysics Data System (ADS)

    Wang, Xiaomei; Teng, Yuntian; Wang, Chen; Ma, Jiemei

    2017-04-01

    The new development instrument with a compact spherical coil system and Overhauser magnetometer for measuring the total strength of the magnetic field and the vectors of strength, Delta inclination - Delta declination, meanwhile we also use a triaxial fluxgate instrument of the traditional instrument for geomagnetic vector filed measurement. The advantages of this method are be calibrated by each other and get good performances with automatic operation, good stability and high resolution. Firstly, a brief description of the instrument measurement principles and the key technologies are given. The instrument used a spherical coil system with 34 coils to product the homogeneous volume inside the coils which is large enough to accommodate the sensor of Overhauser total field sensor; the rest of the footlocker-sized ocean-bottom vector magnetometer consists of equipment to run the sensors and records its data (batteries and a data logger), weight to sink it to the sea floor, a remote-controlled acoustic release and flotation to bring the instrument back to the surface. Finally, the accuracy of the instrument was tested in the Geomagnetic station, and the measurement accuracies of total strength and components were better than 0.2nT and 1nT respectively. The figure 1 shows the development instrument structure. it includes six thick glass spheres which protect the sensor, data logger and batteries from the pressures of the deep sea, meanwhile they also provide recycling positive buoyancy; To cushion the glass, the spheres then go inside yellow plastic "hardhats". The triaxial fluxgate is inside No.1 glass spheres, data logger and batteries are inside No.2 glass spheres, the new vector sensor is inside No.3 glass spheres, acoustic communication unit is inside No.4 glass spheres, No.5 and No.6 glass spheres are empty which only provide recycling positive buoyancy. The figure 2 shows the development instrument Physical photo.

  3. Controlled superficial assembly of DNA-amorphous calcium phosphate nanocomposite spheres for surface-mediated gene delivery.

    PubMed

    Oyane, Ayako; Araki, Hiroko; Nakamura, Maki; Shimizu, Yoshiki; Shubhra, Quazi T H; Ito, Atsuo; Tsurushima, Hideo

    2016-05-01

    Surface-mediated gene delivery systems have many potential applications in tissue engineering. We recently fabricated an assembly consisting of DNA-amorphous calcium phosphate (DNA-ACP) nanocomposite spheres on a polymer substrate via coprecipitation in a labile supersaturated calcium phosphate (CaP) solution and demonstrated the assembly's high gene delivery efficacy. In this study, we conducted a detailed investigation of the coprecipitation process in solution and revealed that the negatively charged DNA molecules were immobilized in the ACP spheres during the initial stage of coprecipitation and functioned as both sphere-dispersing and size-regulating agents. As a result, the DNA-ACP nanocomposites grew into size-regulated submicrospheres in solution and assembled onto the substrate via gravity sedimentation. The assembled nanocomposite spheres were chemically anchored to the substrate surface through an intermediate layer of CaP-based nanoparticles that was formed heterogeneously at the substrate surface. The coprecipitation conditions, i.e., coprecipitation time and Ca and P concentrations in solution, greatly affected the state of assembly of the nanocomposite spheres, thereby influencing the gene expression level of the cells cultured on the substrate. Increasing the number density and decreasing the size of the nanocomposite spheres did not always increase the assembly's gene delivery efficacy (per surface area of the substrate) due to adverse effects on cellular viability. As demonstrated herein, controlling the coprecipitation conditions is important for designing a cell-stimulating and biocompatible scaffold surface consisting of an assembly of DNA-ACP nanocomposite spheres. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Taming cut-off induced artifacts in molecular dynamics studies of solvated polypeptides. The reaction field method.

    PubMed

    Schreiber, H; Steinhauser, O

    1992-12-05

    In this paper we present a model system of a solvated polypeptide, which is a suitable reference platform for the systematic exploration of methods for taming artifacts introduced by an incorrect treatment of long-range Coulomb forces. The essential feature of the system composed of an alpha-helical peptide and 1021 water molecules is the strict neutrality of all charge groups. The dynamical properties of the peptide, i.e. unfolding or maintenance of the helix, already give first hints on the influence of boundary effects. A rigorous and deeper insight is gained, however, if analyzing the system by means of the generalized Kirkwood g-factor, which projects the net dipole moment of concentric spheres onto the respective dipole moment of the reference charge group. The g-factor is a global measure for, and a sensitive probe of, the orientational structure, which in its turn reflects even the smallest inconsistencies in the treatment of long-range forces. While the cut-off scheme failed the g-factor test, the "reaction field" method, the simplest cut-off correction scheme, enables a consistent description. In other words, with the aid of the reaction field, the correct orientational structure is restored. As a consequence, the helix stability is regained and we were able to calculate the dielectric constant epsilon approximately 55 to 60 for our system, which is slightly below the corresponding value epsilon SPC = 66 of the pure solvent.

  5. Influence of diffuse reflectance measurement accuracy on the scattering coefficient in determination of optical properties with integrating sphere optics (a secondary publication).

    PubMed

    Horibe, Takuro; Ishii, Katsunori; Fukutomi, Daichi; Awazu, Kunio

    2015-12-30

    An estimation error of the scattering coefficient of hemoglobin in the high absorption wavelength range has been observed in optical property calculations of blood-rich tissues. In this study, the relationship between the accuracy of diffuse reflectance measurement in the integrating sphere and calculated scattering coefficient was evaluated with a system to calculate optical properties combined with an integrating sphere setup and the inverse Monte Carlo simulation. Diffuse reflectance was measured with the integrating sphere using a small incident port diameter and optical properties were calculated. As a result, the estimation error of the scattering coefficient was improved by accurate measurement of diffuse reflectance. In the high absorption wavelength range, the accuracy of diffuse reflectance measurement has an effect on the calculated scattering coefficient.

  6. Optical rotation of levitated spheres in high vacuum

    NASA Astrophysics Data System (ADS)

    Monteiro, Fernando; Ghosh, Sumita; van Assendelft, Elizabeth C.; Moore, David C.

    2018-05-01

    A circularly polarized laser beam is used to levitate and control the rotation of microspheres in high vacuum. At low pressure, rotation frequencies as high as 6 MHz are observed for birefringent vaterite spheres, limited by centrifugal stresses. Due to the extremely low damping in high vacuum, the controlled optical rotation of amorphous SiO2 spheres is also observed at rates above several MHz. At 10-7 mbar, a damping time of 6 ×104 s is measured for a 10 -μ m -diam SiO2 sphere. No additional damping mechanisms are observed above gas damping, indicating that even longer damping times may be possible with operation at lower pressure. The controlled optical rotation of microspheres at MHz frequencies with low damping, including for materials that are not intrinsically birefringent, provides a tool for performing precision measurements using optically levitated systems.

  7. In Vitro Analysis of Breast Cancer Cell Line Tumourspheres and Primary Human Breast Epithelia Mammospheres Demonstrates Inter- and Intrasphere Heterogeneity

    PubMed Central

    Vargas, Ana Cristina; Keith, Patricia; Reid, Lynne; Wockner, Leesa; Amiri, Marjan Askarian; Sarkar, Debina; Simpson, Peter T.; Clarke, Catherine; Schmidt, Chris W.; Reynolds, Brent A.

    2013-01-01

    Mammosphere and breast tumoursphere culture have gained popularity as in vitro assays for propagating and analysing normal and cancer stem cells. Whether the spheres derived from different sources or parent cultures themselves are indeed single entities enriched in stem/progenitor cells compared to other culture formats has not been fully determined. We surveyed sphere-forming capacity across 26 breast cell lines, immunophenotyped spheres from six luminal- and basal-like lines by immunohistochemistry and flow cytometry and compared clonogenicity between sphere, adherent and matrigel culture formats using in vitro functional assays. Analyses revealed morphological and molecular intra- and inter-sphere heterogeneity, consistent with adherent parental cell line phenotypes. Flow cytometry showed sphere culture does not universally enrich for markers previously associated with stem cell phenotypes, although we found some cell-line specific changes between sphere and adherent formats. Sphere-forming efficiency was significantly lower than adherent or matrigel clonogenicity and constant over serial passage. Surprisingly, self-renewal capacity of sphere-derived cells was similar/lower than other culture formats. We observed significant correlation between long-term-proliferating-cell symmetric division rates in sphere and adherent cultures, suggesting functional overlap between the compartments sustaining them. Experiments with normal primary human mammary epithelia, including sorted luminal (MUC1+) and basal/myoepithelial (CD10+) cells revealed distinct luminal-like, basal-like and mesenchymal entities amongst primary mammospheres. Morphological and colony-forming-cell assay data suggested mammosphere culture may enrich for a luminal progenitor phenotype, or induce reversion/relaxation of the basal/mesenchymal in vitro selection occurring with adherent culture. Overall, cell line tumourspheres and primary mammospheres are not homogenous entities enriched for stem cells, suggesting a more cautious approach to interpreting data from these assays and careful consideration of its limitations. Sphere culture may represent an alternative 3-dimensional culture system which rather than universally ‘enriching’ for stem cells, has utility as one of a suite of functional assays that provide a read-out of progenitor activity. PMID:23750209

  8. Emissivity measurements of shocked tin using a multi-wavelength integrating sphere

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seifter, A; Holtkamp, D B; Iverson, A J

    Pyrometric measurements of radiance to determine temperature have been performed on shock physics experiments for decades. However, multi-wavelength pyrometry schemes sometimes fail to provide credible temperatures in experiments, which incur unknown changes in sample emissivity, because an emissivity change also affects the spectral radiance. Hence, for shock physics experiments using pyrometry to measure temperatures, it is essential to determine the dynamic sample emissivity. The most robust way to determine the normal spectral emissivity is to measure the spectral normal-hemispherical reflectance using an integrating sphere. In this paper we describe a multi-wavelength (1.6–5.0 μm) integrating sphere system that utilizes a “reversed”more » scheme, which we use for shock physics experiments. The sample to be shocked is illuminated uniformly by scattering broadband light from inside a sphere onto the sample. A portion of the light reflected from the sample is detected at a point 12° from normal to the sample surface. For this experiment, we used the system to measure emissivity of shocked tin at four wavelengths for shock stress values between 17 and 33 GPa. The results indicate a large increase in effective emissivity upon shock release from tin when the shock is above 24–25 GPa, a shock stress that partially melts the sample. We also recorded an IR image of one of the shocked samples through the integrating sphere, and the emissivity inferred from the image agreed well with the integrating-sphere, pyrometer-detector data. Here, we discuss experimental data, uncertainties, and a data analysis process. We also describe unique emissivity-measurement problems arising from shock experiments and methods to overcome such problems.« less

  9. Reliability of mobile systems in construction

    NASA Astrophysics Data System (ADS)

    Narezhnaya, Tamara; Prykina, Larisa

    2017-10-01

    The purpose of the article is to analyze the influence of the mobility of construction production in the article taking into account the properties of reliability and readiness. Basing on the studied systems the effectiveness and efficiency is estimated. The construction system is considered to be the complete organizational structure providing creation or updating of construction facilities. At the same time the production sphere of these systems joins the production on the building site itself, material and technical resources of the construction production and live labour in these spheres within the construction dynamics. The author concludes, that the estimation of the degree of mobility of systems the of construction production makes a great positive effect in the project.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pratt, Lawrence R.; Chaudhari, Mangesh I.; Rempe, Susan B.

    Here this review focuses on the striking recent progress in solving for hydrophobic interactions between small inert molecules. We discuss several new understandings. First, the inverse temperature phenomenology of hydrophobic interactions, i.e., strengthening of hydrophobic bonds with increasing temperature, is decisively exhibited by hydrophobic interactions between atomic-scale hard sphere solutes in water. Second, inclusion of attractive interactions associated with atomic-size hydrophobic reference cases leads to substantial, nontrivial corrections to reference results for purely repulsive solutes. Hydrophobic bonds are weakened by adding solute dispersion forces to treatment of reference cases. The classic statistical mechanical theory for those corrections is not accuratemore » in this application, but molecular quasi-chemical theory shows promise. Lastly, because of the masking roles of excluded volume and attractive interactions, comparisons that do not discriminate the different possibilities face an interpretive danger.« less

  11. Obtaining the Bidirectional Transfer Distribution Function ofIsotropically Scattering Materials Using an Integrating Sphere

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jonsson, Jacob C.; Branden, Henrik

    2006-10-19

    This paper demonstrates a method to determine thebidirectional transfer distribution function (BTDF) using an integratingsphere. Information about the sample's angle dependent scattering isobtained by making transmittance measurements with the sample atdifferent distances from the integrating sphere. Knowledge about theilluminated area of the sample and the geometry of the sphere port incombination with the measured data combines to an system of equationsthat includes the angle dependent transmittance. The resulting system ofequations is an ill-posed problem which rarely gives a physical solution.A solvable system is obtained by using Tikhonov regularization on theill-posed problem. The solution to this system can then be usedmore » to obtainthe BTDF. Four bulk-scattering samples were characterised using both twogoniophotometers and the described method to verify the validity of thenew method. The agreement shown is great for the more diffuse samples.The solution to the low-scattering samples contains unphysicaloscillations, butstill gives the correct shape of the solution. Theorigin of the oscillations and why they are more prominent inlow-scattering samples are discussed.« less

  12. An Automated Flying-Insect-Detection System

    NASA Technical Reports Server (NTRS)

    Vann, Timi; Andrews, Jane C.; Howell, Dane; Ryan, Robert

    2005-01-01

    An automated flying-insect-detection system (AFIDS) was developed as a proof-of-concept instrument for real-time detection and identification of flying insects. This type of system has use in public health and homeland security decision support, agriculture and military pest management, and/or entomological research. Insects are first lured into the AFIDS integrated sphere by insect attractants. Once inside the sphere, the insect's wing beats cause alterations in light intensity that is detected by a photoelectric sensor. Following detection, the insects are encouraged (with the use of a small fan) to move out of the sphere and into a designated insect trap where they are held for taxonomic identification or serological testing. The acquired electronic wing beat signatures are preprocessed (Fourier transformed) in real-time to display a periodic signal. These signals are sent to the end user where they are graphically displayed. All AFIDS data are pre-processed in the field with the use of a laptop computer equipped with LABVIEW. The AFIDS software can be programmed to run continuously or at specific time intervals when insects are prevalent. A special DC-restored transimpedance amplifier reduces the contributions of low-frequency background light signals, and affords approximately two orders of magnitude greater AC gain than conventional amplifiers. This greatly increases the signal-to-noise ratio and enables the detection of small changes in light intensity. The AFIDS light source consists of high-intensity Al GaInP light-emitting diodes (LEDs). The AFIDS circuitry minimizes brightness fluctuations in the LEDs and when integrated with an integrating sphere, creates a diffuse uniform light field. The insect wing beats isotropically scatter the diffuse light in the sphere and create wing beat signatures that are detected by the sensor. This configuration minimizes variations in signal associated with insect flight orientation.

  13. An efficient implementation of a high-order filter for a cubed-sphere spectral element model

    NASA Astrophysics Data System (ADS)

    Kang, Hyun-Gyu; Cheong, Hyeong-Bin

    2017-03-01

    A parallel-scalable, isotropic, scale-selective spatial filter was developed for the cubed-sphere spectral element model on the sphere. The filter equation is a high-order elliptic (Helmholtz) equation based on the spherical Laplacian operator, which is transformed into cubed-sphere local coordinates. The Laplacian operator is discretized on the computational domain, i.e., on each cell, by the spectral element method with Gauss-Lobatto Lagrange interpolating polynomials (GLLIPs) as the orthogonal basis functions. On the global domain, the discrete filter equation yielded a linear system represented by a highly sparse matrix. The density of this matrix increases quadratically (linearly) with the order of GLLIP (order of the filter), and the linear system is solved in only O (Ng) operations, where Ng is the total number of grid points. The solution, obtained by a row reduction method, demonstrated the typical accuracy and convergence rate of the cubed-sphere spectral element method. To achieve computational efficiency on parallel computers, the linear system was treated by an inverse matrix method (a sparse matrix-vector multiplication). The density of the inverse matrix was lowered to only a few times of the original sparse matrix without degrading the accuracy of the solution. For better computational efficiency, a local-domain high-order filter was introduced: The filter equation is applied to multiple cells, and then the central cell was only used to reconstruct the filtered field. The parallel efficiency of applying the inverse matrix method to the global- and local-domain filter was evaluated by the scalability on a distributed-memory parallel computer. The scale-selective performance of the filter was demonstrated on Earth topography. The usefulness of the filter as a hyper-viscosity for the vorticity equation was also demonstrated.

  14. Effects of Energy Dissipation in the Sphere-Restricted Full Three-Body Problem

    NASA Astrophysics Data System (ADS)

    Gabriel, T. S. J.

    Recently, the classical N-Body Problem has been adjusted to account for celestial bodies made of constituents of finite density. By imposing a minima on the achievable distance between particles, minimum energy resting states are allowed by the problem. The Full N-Body Problem allows for the dissipation of mechanical energy through surface-surface interactions via impacts or by way of tidal deformation. Barring exogeneous forces and allowing for the dissipation of energy, these systems have discrete, and sometimes multiple, minimum energy states for a given angular momentum. Building the dynamical framework of such finite density systems is a necessary process in outlining the evolution of rubble pile asteroids and other gravitational-granular systems such as protoplanetary discs, and potentially planetary rings, from a theoretical point of view. In all cases, resting states are expected to occur as a necessary step in the ongoing processes of solar system formation and evolution. Previous studies of this problem have been performed in the N=3 case where the bodies are indistinguishable spheres, with all possible relative equilibria and their stability having been identified as a function of the angular momentum of the system. These studies uncovered that at certain levels of angular momentum there exists two minimum energy states, a global and local minimum. Thus a question of interest is in which of these states a dissipative system would preferentially settle and the sensitivity of results to changes in dissipation parameters. Assuming equal-sized, perfectly-rigid bodies, this study investigates the dynamical evolution of three spheres under the influence of mutual gravity and impact mechanics as a function of dissipation parameters. A purpose-written, C-based, Hard Sphere Discrete Element Method code has been developed to integrate trajectories and resolve contact mechanics as grains evolve into minimum energy configurations. By testing many randomized initial conditions, statistics are measured regarding minimum energy states for a given angular momentum range. A trend in the Sphere-Restricted Full Three-Body Problem producing an end state of one configuration over another is found as a function of angular momentum and restitution.

  15. TH-C-17A-06: A Hardware Implementation and Evaluation of Robotic SPECT: Toward Molecular Imaging Onboard Radiation Therapy Machines

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yan, S; Touch, M; Bowsher, J

    Purpose: To construct a robotic SPECT system and demonstrate its capability to image a thorax phantom on a radiation therapy flat-top couch. The system has potential for on-board functional and molecular imaging in radiation therapy. Methods: A robotic SPECT imaging system was developed utilizing a Digirad 2020tc detector and a KUKA KR150-L110 robot. An imaging study was performed with the PET CT Phantom, which includes 5 spheres: 10, 13, 17, 22 and 28 mm in diameter. Sphere-tobackground concentration ratio was 6:1 of Tc99m. The phantom was placed on a flat-top couch. SPECT projections were acquired with a parallel-hole collimator andmore » a single pinhole collimator. The robotic system navigated the detector tracing the flat-top table to maintain the closest possible proximity to the phantom. For image reconstruction, detector trajectories were described by six parameters: radius-of-rotation, x and z detector shifts, and detector rotation θ, tilt ϕ and twist γ. These six parameters were obtained from the robotic system by calibrating the robot base and tool coordinates. Results: The robotic SPECT system was able to maneuver parallel-hole and pinhole collimated SPECT detectors in close proximity to the phantom, minimizing impact of the flat-top couch on detector-to-COR (center-ofrotation) distance. In acquisitions with background at 1/6th sphere activity concentration, photopeak contamination was heavy, yet the 17, 22, and 28 mm diameter spheres were readily observed with the parallel hole imaging, and the single, targeted sphere (28 mm diameter) was readily observed in the pinhole region-of-interest (ROI) imaging. Conclusion: Onboard SPECT could be achieved by a robot maneuvering a SPECT detector about patients in position for radiation therapy on a flat-top couch. The robot inherent coordinate frame could be an effective means to estimate detector pose for use in SPECT image reconstruction. PHS/NIH/NCI grant R21-CA156390-01A1.« less

  16. Experimental determination of the dynamics of an acoustically levitated sphere

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pérez, Nicolás, E-mail: nico@fisica.edu.uy; Andrade, Marco A. B.; Canetti, Rafael

    2014-11-14

    Levitation of solids and liquids by ultrasonic standing waves is a promising technique to manipulate materials without contact. When a small particle is introduced in certain areas of a standing wave field, the acoustic radiation force pushes the particle to the pressure node. This movement is followed by oscillations of the levitated particle. Aiming to investigate the particle oscillations in acoustic levitation, this paper presents the experimental and numerical characterization of the dynamic behavior of a levitated sphere. To obtain the experimental response, a small sphere is lifted by the acoustic radiation force. After the sphere lift, it presents amore » damped oscillatory behavior, which is recorded by a high speed camera. To model this behavior, a mass-spring-damper system is proposed. In this model, the acoustic radiation force that acts on the sphere is theoretically predicted by the Gor'kov theory and the viscous forces are modeled by two damping terms, one term proportional to the square of the velocity and another term proportional to the particle velocity. The proposed model was experimentally verified by using different values of sound pressure amplitude. The comparison between numerical and experimental results shows that the model can accurately describe the oscillatory behavior of the sphere in an acoustic levitator.« less

  17. Research on effects of baffle position in an integrating sphere on the luminous flux measurement

    NASA Astrophysics Data System (ADS)

    Lin, Fangsheng; Li, Tiecheng; Yin, Dejin; Lai, Lei; Xia, Ming

    2016-09-01

    In the field of optical metrology, luminous flux is an important index to characterize the quality of electric light source. Currently, the majority of luminous flux measurement is based on the integrating sphere method, so measurement accuracy of integrating sphere is the key factor. There are plenty of factors affecting the measurement accuracy, such as coating, power and the position of light source. However, the baffle which is a key part of integrating sphere has important effects on the measurement results. The paper analyzes in detail the principle of an ideal integrating sphere. We use moving rail to change the relative position of baffle and light source inside the sphere. By experiments, measured luminous flux values at different distances between the light source and baffle are obtained, which we used to take analysis of the effects of different baffle position on the measurement. By theoretical calculation, computer simulation and experiment, we obtain the optimum position of baffle for luminous flux measurements. Based on the whole luminous flux measurement error analysis, we develop the methods and apparatus to improve the luminous flux measurement accuracy and reliability. It makes our unifying and transferring work of the luminous flux more accurate in East China and provides effective protection for our traceability system.

  18. Experimental determination of the dynamics of an acoustically levitated sphere

    NASA Astrophysics Data System (ADS)

    Pérez, Nicolás; Andrade, Marco A. B.; Canetti, Rafael; Adamowski, Julio C.

    2014-11-01

    Levitation of solids and liquids by ultrasonic standing waves is a promising technique to manipulate materials without contact. When a small particle is introduced in certain areas of a standing wave field, the acoustic radiation force pushes the particle to the pressure node. This movement is followed by oscillations of the levitated particle. Aiming to investigate the particle oscillations in acoustic levitation, this paper presents the experimental and numerical characterization of the dynamic behavior of a levitated sphere. To obtain the experimental response, a small sphere is lifted by the acoustic radiation force. After the sphere lift, it presents a damped oscillatory behavior, which is recorded by a high speed camera. To model this behavior, a mass-spring-damper system is proposed. In this model, the acoustic radiation force that acts on the sphere is theoretically predicted by the Gor'kov theory and the viscous forces are modeled by two damping terms, one term proportional to the square of the velocity and another term proportional to the particle velocity. The proposed model was experimentally verified by using different values of sound pressure amplitude. The comparison between numerical and experimental results shows that the model can accurately describe the oscillatory behavior of the sphere in an acoustic levitator.

  19. Beyond the Black-White Binary of U.S. Race Relations: A Next Step in Religious Education

    ERIC Educational Resources Information Center

    Goto, Courtney T.

    2017-01-01

    Many if not most people in the academy as well as the public sphere tend to regard race and racism in the United States in terms of a default frame of reference (i.e., a paradigm): the black-white binary. Although this frame is constructive as well as compelling, it displays serious liabilities. This article outlines, for religious educators, nine…

  20. Fisheye camera method for spatial non-uniformity corrections in luminous flux measurements with integrating spheres

    NASA Astrophysics Data System (ADS)

    Kokka, Alexander; Pulli, Tomi; Poikonen, Tuomas; Askola, Janne; Ikonen, Erkki

    2017-08-01

    This paper presents a fisheye camera method for determining spatial non-uniformity corrections in luminous flux measurements with integrating spheres. Using a fisheye camera installed into a port of an integrating sphere, the relative angular intensity distribution of the lamp under test is determined. This angular distribution is used for calculating the spatial non-uniformity correction for the lamp when combined with the spatial responsivity data of the sphere. The method was validated by comparing it to a traditional goniophotometric approach when determining spatial correction factors for 13 LED lamps with different angular spreads. The deviations between the spatial correction factors obtained using the two methods ranged from -0.15 % to 0.15%. The mean magnitude of the deviations was 0.06%. For a typical LED lamp, the expanded uncertainty (k = 2 ) for the spatial non-uniformity correction factor was evaluated to be 0.28%. The fisheye camera method removes the need for goniophotometric measurements in determining spatial non-uniformity corrections, thus resulting in considerable system simplification. Generally, no permanent modifications to existing integrating spheres are required.

  1. Performance evaluation of a high resolution dedicated breast PET scanner

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    García Hernández, Trinitat, E-mail: mtrinitat@eresa.com; Vicedo González, Aurora; Brualla González, Luis

    2016-05-15

    Purpose: Early stage breast cancers may not be visible on a whole-body PET scan. To overcome whole-body PET limitations, several dedicated breast positron emission tomography (DbPET) systems have emerged nowadays aiming to improve spatial resolution. In this work the authors evaluate the performance of a high resolution dedicated breast PET scanner (Mammi-PET, Oncovision). Methods: Global status, uniformity, sensitivity, energy, and spatial resolution were measured. Spheres of different sizes (2.5, 4, 5, and 6 mm diameter) and various 18 fluorodeoxyglucose ({sup 18}F-FDG) activity concentrations were randomly inserted in a gelatine breast phantom developed at our institution. Several lesion-to-background ratios (LBR) weremore » simulated, 5:1, 10:1, 20:1, 30:1, and 50:1. Images were reconstructed using different voxel sizes. The ability of experienced reporters to detect spheres was tested as a function of acquisition time, LBR, sphere size, and matrix reconstruction voxel size. For comparison, phantoms were scanned in the DbPET camera and in a whole body PET (WB-PET). Two patients who just underwent WB-PET/CT exams were imaged with the DbPET system and the images were compared. Results: The measured absolute peak sensitivity was 2.0%. The energy resolution was 24.0% ± 1%. The integral and differential uniformity were 10% and 6% in the total field of view (FOV) and 9% and 5% in the central FOV, respectively. The measured spatial resolution was 2.0, 1.9, and 1.7 mm in the radial, tangential, and axial directions. The system exhibited very good detectability for spheres ≥4 mm and LBR ≥10 with a sphere detection of 100% when acquisition time was set >3 min/bed. For LBR = 5 and acquisition time of 7 min the detectability was 100% for spheres of 6 mm and 75% for spheres of 5, 4, and 2.5 mm. Lesion WB-PET detectability was only comparable to the DbPET camera for lesion sizes ≥5 mm when acquisition time was >3 min and LBR > 10. Conclusions: The DbPET has a good performance for its clinical use and shows an improved resolution and lesion detectability of small lesions compared to WB-PET.« less

  2. ALGORITHM BASED ON ARTIFICIAL BEE COLONY FOR UNFOLDING OF NEUTRON SPECTRA OBTAINED WITH BONNER SPHERES.

    PubMed

    Silva, Everton R; Freitas, Bruno M; Santos, Denison S; Maurício, Cláudia L P

    2018-04-13

    Occupational neutron fields usually have energies from the thermal range to some MeV and the characterization of the spectra is essential for estimation of the radioprotection quantities. Thus, the spectrum must be unfolded based on a limited number of measurements. This study implemented an algorithm based on the bee colonies behavior, named Artificial Bee Colony (ABC), where the intelligent behavior of the bees in search of food is reproduced to perform the unfolding of neutron spectra. The experimental measurements used Bonner spheres and 6LiI (Eu) detector, with irradiations using a thermal neutron flux and three reference fields: 241Am-Be, 252Cf and 252Cf (D2O). The ABC obtained good estimation of the expected spectrum even without previous information and its results were closer to expected spectra than those obtained by the SPUNIT algorithm.

  3. Selenium adsorption to aluminum-based water treatment residuals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ippolito, James A.; Scheckel, Kirk G.; Barbarick, Ken A.

    2009-09-02

    Aluminum-based water treatment residuals (WTR) can adsorb water- and soil-borne P, As(V), As(III), and perchlorate, and may be able to adsorb excess environmental selenium. WTR, clay minerals, and amorphous aluminum hydroxide were shaken for 24 h in selenate or selenite solutions at pH values of 5-9, and then analyzed for selenium content. Selenate and selenite adsorption edges were unaffected across the pH range studied. Selenate adsorbed on to WTR, reference mineral phases, and amorphous aluminum hydroxide occurred as outer sphere complexes (relatively loosely bound), while selenite adsorption was identified as inner-sphere complexation (relatively tightly bound). Selenite sorption to WTR inmore » an anoxic environment reduced Se(IV) to Se(0), and oxidation of Se(0) or Se(IV) appeared irreversible once sorbed to WTR. Al-based WTR could play a favorable role in sequestering excess Se in affected water sources.« less

  4. SPHERES

    NASA Image and Video Library

    2013-08-27

    ISS036-E-037288 (27 Aug. 2013) --- In the International Space Station?s Kibo laboratory, NASA astronaut Karen Nyberg, Expedition 36 flight engineer, conducts a session with a pair of bowling-ball-sized free-flying satellites known as Synchronized Position Hold, Engage, Reorient, Experimental Satellites, or SPHERES. Surrounding the two SPHERES mini-satellites with ring-shaped hardware known as the Resonant Inductive Near-field Generation System, or RINGS, Nyberg performed a demonstration of how power can be transferred between two satellites without physical contact. Station crews beginning with Expedition 8 have operated these robots to test techniques that could lead to advancements in automated dockings, satellite servicing, spacecraft assembly and emergency repairs.

  5. Greenhouse effect: temperature of a metal sphere surrounded by a glass shell and heated by sunlight

    NASA Astrophysics Data System (ADS)

    Nguyen, Phuc H.; Matzner, Richard A.

    2012-01-01

    We study the greenhouse effect on a model satellite consisting of a tungsten sphere surrounded by a thin spherical, concentric glass shell, with a small gap between the sphere and the shell. The system sits in vacuum and is heated by sunlight incident along the z-axis. This development is a generalization of the simple treatment of the greenhouse effect given by Kittel and Kroemer (1980 Thermal Physics (San Francisco: Freeman)) and can serve as a very simple model demonstrating the much more complex Earth greenhouse effect. Solution of the model problem provides an excellent pedagogical tool at the Junior/Senior undergraduate level.

  6. The art of nomograms.

    PubMed

    Arba Mosquera, Samuel; de Ortueta, Diego; Verma, Shwetabh

    2018-01-01

    To retrospectively analyse strategies for adjusting refractive surgery plans with reference to the preoperative manifest refraction. We constructed seven nomograms based on the refractive outcomes (sphere, cylinder, axis [SCA]) of 150 consecutive eyes treated with laser in situ keratomileusis for myopic astigmatism. We limited the initial data to the SCA of the manifest refraction. All nomograms were based on the strategy: if for x diopters (D) of attempted metric, y D is achieved; we can reverse this sentence and state for achieving y D of change in the metric, x D will be planned. The effects of the use of plus or minus astigmatism notation, spherical equivalent, sphere, principal meridians notation, cardinal and oblique astigmatism, and astigmatic axis were incorporated. All nomograms detected subtle differences in the spherical component ( p  < 0.0001). Nomograms 5 and 7 (using power vectors) and 6 (considering axis shifts) detected significant astigmatic differences (nomogram 5, p  < 0.001; nomogram 6, p  < 0.05; nomogram 7, p  < 0.005 for cardinal astigmatism, p  = 0.1 for oblique astigmatism). We observed mild clinically relevant differences (~ 0.5 D) in sphere or astigmatism among the nomograms; differences of ~ 0.25 D in the proposals for sphere or cylinder were not uncommon. All nomograms suggested minor improvements versus actual observed outcomes, with no clinically relevant differences among them. All nomograms anticipated minor improvements versus actual observed outcomes without clinically relevant differences among them. The minimal uncertainties in determining the manifest refraction (~ 0.6 D) are the major limitation to improving the accuracy of refractive surgery nomograms.

  7. Rolling contact of a rigid sphere/sliding of a spherical indenter upon a viscoelastic half-space containing an ellipsoidal inhomogeneity

    NASA Astrophysics Data System (ADS)

    Koumi, Koffi Espoir; Chaise, Thibaut; Nelias, Daniel

    2015-07-01

    In this paper, the frictionless rolling contact problem between a rigid sphere and a viscoelastic half-space containing one elastic inhomogeneity is solved. The problem is equivalent to the frictionless sliding of a spherical tip over a viscoelastic body. The inhomogeneity may be of spherical or ellipsoidal shape, the later being of any orientation relatively to the contact surface. The model presented here is three dimensional and based on semi-analytical methods. In order to take into account the viscoelastic aspect of the problem, contact equations are discretized in the spatial and temporal dimensions. The frictionless rolling of the sphere, assumed rigid here for the sake of simplicity, is taken into account by translating the subsurface viscoelastic fields related to the contact problem. Eshelby's formalism is applied at each step of the temporal discretization to account for the effect of the inhomogeneity on the contact pressure distribution, subsurface stresses, rolling friction and the resulting torque. A Conjugate Gradient Method and the Fast Fourier Transforms are used to reduce the computation cost. The model is validated by a finite element model of a rigid sphere rolling upon a homogeneous vciscoelastic half-space, as well as through comparison with reference solutions from the literature. A parametric analysis of the effect of elastic properties and geometrical features of the inhomogeneity is performed. Transient and steady-state solutions are obtained. Numerical results about the contact pressure distribution, the deformed surface geometry, the apparent friction coefficient as well as subsurface stresses are presented, with or without heterogeneous inclusion.

  8. Effects of shape and size of agar gels on heating uniformity during pulsed microwave treatment.

    PubMed

    Soto-Reyes, Nohemí; Temis-Pérez, Ana L; López-Malo, Aurelio; Rojas-Laguna, Roberto; Sosa-Morales, María Elena

    2015-05-01

    Model gel systems with different shape (sphere, cylinder, and slab) and size (180 and 290 g) were prepared with agar (5%) and sucrose (5%). Dielectric constant (ε'), loss factor (ε"), thermophysical properties, and temperature distribution of the model system were measured. Each agar model system was immersed and suspended in water, and then, heated in a microwave oven with intermittent heating until the core temperature reached 50 °C. The ε' and ε" of agar gels decreased when frequency increased. The density and thermal conductivity values of the agar gels were 1033 kg/m(3) and 0.55 W/m °C, respectively. The temperature distribution of sphere, cylinder, and slab was different when similar power doses were applied. The slab reached 50 °C in less time (10 min) and showed a more uniform heating than spheres and cylinders in both sizes. Agar model systems of 180 g heated faster than those of 290 g. The coldest point was the center of the model systems in all studied cases. Shape and size are critical food factors that affect the heating uniformity during microwave heating processes. © 2015 Institute of Food Technologists®

  9. Equation of state and critical point behavior of hard-core double-Yukawa fluids.

    PubMed

    Montes, J; Robles, M; López de Haro, M

    2016-02-28

    A theoretical study on the equation of state and the critical point behavior of hard-core double-Yukawa fluids is presented. Thermodynamic perturbation theory, restricted to first order in the inverse temperature and having the hard-sphere fluid as the reference system, is used to derive a relatively simple analytical equation of state of hard-core multi-Yukawa fluids. Using such an equation of state, the compressibility factor and phase behavior of six representative hard-core double-Yukawa fluids are examined and compared with available simulation results. The effect of varying the parameters of the hard-core double-Yukawa intermolecular potential on the location of the critical point is also analyzed using different perspectives. The relevance of this analysis for fluids whose molecules interact with realistic potentials is also pointed out.

  10. Electrical resistivity of liquid Na-alkali alloys

    NASA Astrophysics Data System (ADS)

    Malan, Rajesh C.; Vora, Aditya M.

    2018-05-01

    The electrical resistivity (ρ) has been investigated for the liquid Na-alkali alloys. An effort is made to extend the applicability of the potential suggested by Fiolhais and co-workers to the liquid range for alkali group. The universal parameters of the potential are used for the entire calculation. Eight different screening functions proposed by Hartree (H), Hubbard and Sham (HS), Vashishtha and Shingwi (VS), Taylor (T), Ichimaru and Utsumi (IU), Farid et al. (F), Sarkar et al. (S) and Nagy (N) are used to study the electrical resistivity (ρ) of liquid Na-alkali alloys with well-known Faber-Ziman theory along with Percus-Yevic hard sphere (PYHS) reference system. The results of electrical resistivity (ρ) are found in qualitative agreement with experimental data for the Na-K and Na-Rb alloys than those for Na-Li and Na-Cs alloys.

  11. Comparison of Temperature Measurements in the Middle Atmosphere by Satellite with Profiles Obtained by Meteorological Rockets

    NASA Technical Reports Server (NTRS)

    Goldberg, Richard A.; Schmidlin, Francis J.; Feofilov, Artem; Bedrick, M.; Rose, R. Lynn

    2012-01-01

    Measurements using the inflatable falling sphere technique have occasionally been used to obtain temperature results from density data and thereby provide comparison with temperature profiles obtained by satellite sounders in the mesosphere and stratosphere. To insure density measurements within narrow time frames and close in space, the inflatable falling sphere is launched within seconds of the nearly overhead satellite pass. Sphere measurements can be used to validate remotely measured temperatures but also have the advantage of measuring small-scale atmospheric features. Even so, with the dearth of remaining falling spheres available (the manufacture of these systems has been discontinued), it may be time to consider whether the remote measurements are mature enough to stand alone. Three field studies are considered, one in 2003 from Northern Sweden, and two in 2010 from the vicinity of Kwajalein Atoll in the South Pacific and from Barking Sands, Hawaii. All three sites are used to compare temperature retrievals between satellite and in situ falling spheres. The major satellite instruments employed are SABER, MLS, and AIRS. The comparisons indicate that remotely measured temperatures mimic the sphere temperature measurements quite well. The data also confirm that satellite retrievals, while not always at the exact location required for detailed studies in space and time, compare sufficiently well to be highly useful. Although the falling sphere will provide a measurement at a specific location and time, satellites only pass a given location daily or less frequently. This report reveals that averaged satellite measurements can provide temperatures and densities comparable to those obtained from the falling sphere, thereby providing a reliable measure of global temperature

  12. Electrorotation of a metal sphere immersed in an electrolyte of finite Debye length.

    PubMed

    García-Sánchez, Pablo; Ramos, Antonio

    2015-11-01

    We theoretically study the rotation induced on a metal sphere immersed in an electrolyte and subjected to a rotating electric field. The rotation arises from the interaction of the field with the electric charges induced at the metal-electrolyte interface, i.e., the induced electrical double layer (EDL). Particle rotation is due to the torque on the induced dipole, and also from induced-charge electro-osmostic flow (ICEO). The interaction of the electric field with the induced dipole on the system gives rise to counterfield rotation, i.e., the direction opposite to the rotation of the electric field. ICEO generates co-field rotation of the sphere. For thin EDL, ICEO generates negligible rotation. For increasing size of EDL, co-field rotation appears and, in the limit of very thick EDL, it compensates the counter-field rotation induced by the electrical torque. We also report computations of the rotating fluid velocity field around the sphere.

  13. Monte Carlo simulation of hard spheres near random closest packing using spherical boundary conditions

    NASA Astrophysics Data System (ADS)

    Tobochnik, Jan; Chapin, Phillip M.

    1988-05-01

    Monte Carlo simulations were performed for hard disks on the surface of an ordinary sphere and hard spheres on the surface of a four-dimensional hypersphere. Starting from the low density fluid the density was increased to obtain metastable amorphous states at densities higher than previously achieved. Above the freezing density the inverse pressure decreases linearly with density, reaching zero at packing fractions equal to 68% for hard spheres and 84% for hard disks. Using these new estimates for random closest packing and coefficients from the virial series we obtain an equation of state which fits all the data up to random closest packing. Usually, the radial distribution function showed the typical split second peak characteristic of amorphous solids and glasses. High density systems which lacked this split second peak and showed other sharp peaks were interpreted as signaling the onset of crystal nucleation.

  14. Functionalization of Carbon Spheres with a Porphyrin-Ferrocene Dyad.

    PubMed

    Possanza, Fabio; Limosani, Francesca; Tagliatesta, Pietro; Zanoni, Robertino; Scarselli, Manuela; Ciotta, Erica; Pizzoferrato, Roberto

    2018-05-21

    Meso-tetraphenylporphyrin connected with a ferrocene molecule in the beta-position of the macrocycle through a triple carbon-carbon bond has been bound to carbon spheres using the Prato-Maggini reaction. The ethynyl or/and phenylene ethynylene subunits were chosen as a linking bridge to give a high conjugation degree between the donor (i. e., ferrocene), the photoactive compound (i. e., porphyrin), and the acceptor (i. e., carbon spheres). The molecular bridges have been directly linked to the beta-pyrrole positions of the porphyrin ring, generating a new example of a long-range donor-acceptor system. Steady-state fluorescence studies together with Raman and XPS measurements helped understanding the chemical and physical properties of the porphyrin ring in the new adduct. The spectroscopic characteristics were also compared with those obtained from a similar compound bearing fullerene instead of carbon spheres. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Impact of roughness on the instability of a free-cooling granular gas

    NASA Astrophysics Data System (ADS)

    Garzó, Vicente; Santos, Andrés; Kremer, Gilberto M.

    2018-05-01

    A linear stability analysis of the hydrodynamic equations with respect to the homogeneous cooling state is carried out to identify the conditions for stability of a granular gas of rough hard spheres. The description is based on the results for the transport coefficients derived from the Boltzmann equation for inelastic rough hard spheres [Phys. Rev. E 90, 022205 (2014), 10.1103/PhysRevE.90.022205], which take into account the complete nonlinear dependence of the transport coefficients and the cooling rate on the coefficients of normal and tangential restitution. As expected, linear stability analysis shows that a doubly degenerate transversal (shear) mode and a longitudinal ("heat") mode are unstable with respect to long enough wavelength excitations. The instability is driven by the shear mode above a certain inelasticity threshold; at larger inelasticity, however, the instability is driven by the heat mode for an inelasticity-dependent range of medium roughness. Comparison with the case of a granular gas of inelastic smooth spheres confirms previous simulation results about the dual role played by surface friction: while small and large levels of roughness make the system less unstable than the frictionless system, the opposite happens at medium roughness. On the other hand, such an intermediate window of roughness values shrinks as inelasticity increases and eventually disappears at a certain value, beyond which the rough-sphere gas is always less unstable than the smooth-sphere gas. A comparison with some preliminary simulation results shows a very good agreement for conditions of practical interest.

  16. Adjustable link for kinematic mounting systems

    DOEpatents

    Hale, Layton C.

    1997-01-01

    An adjustable link for kinematic mounting systems. The adjustable link is a low-cost, passive device that provides backlash-free adjustment along its single constraint direction and flexural freedom in all other directions. The adjustable link comprises two spheres, two sockets in which the spheres are adjustable retain, and a connection link threadly connected at each end to the spheres, to provide a single direction of restraint and to adjust the length or distance between the sockets. Six such adjustable links provide for six degrees of freedom for mounting an instrument on a support. The adjustable link has applications in any machine or instrument requiring precision adjustment in six degrees of freedom, isolation from deformations of the supporting platform, and/or additional structural damping. The damping is accomplished by using a hollow connection link that contains an inner rod and a viscoelastic separation layer between the two.

  17. Adjustable link for kinematic mounting systems

    DOEpatents

    Hale, L.C.

    1997-07-01

    An adjustable link for kinematic mounting systems is disclosed. The adjustable link is a low-cost, passive device that provides backlash-free adjustment along its single constraint direction and flexural freedom in all other directions. The adjustable link comprises two spheres, two sockets in which the spheres are adjustable retain, and a connection link threadly connected at each end to the spheres, to provide a single direction of restraint and to adjust the length or distance between the sockets. Six such adjustable links provide for six degrees of freedom for mounting an instrument on a support. The adjustable link has applications in any machine or instrument requiring precision adjustment in six degrees of freedom, isolation from deformations of the supporting platform, and/or additional structural damping. The damping is accomplished by using a hollow connection link that contains an inner rod and a viscoelastic separation layer between the two. 3 figs.

  18. A Design Study of the Inflated Sphere Landing Vehicle, Including the Landing Performance and the Effects of Deviations from Design Conditions

    NASA Technical Reports Server (NTRS)

    Martin, E. Dale

    1961-01-01

    The impact motion of the inflated sphere landing vehicle with a payload centrally supported from the spherical skin by numerous cords has been determined on the assumption of uniform isentropic gas compression during impact. The landing capabilities are determined for a system containing suspension cords of constant cross section. The effects of deviations in impact velocity and initial gas temperature from the design conditions are studied. Also discussed are the effects of errors in the time at which the skin is ruptured. These studies indicate how the design parameters should be chosen to insure reliability of the landing system. Calculations have been made and results are presented for a sphere inflated with hydrogen, landing on the moon in the absence of an atmosphere. The results are presented for one value of the skin-strength parameter.

  19. Effect of inertia on laminar swimming and flying of an assembly of rigid spheres in an incompressible viscous fluid.

    PubMed

    Felderhof, B U

    2015-01-01

    A mechanical model of swimming and flying in an incompressible viscous fluid in the absence of gravity is studied on the basis of assumed equations of motion. The system is modeled as an assembly of rigid spheres subject to elastic direct interactions and to periodic actuating forces which sum to zero. Hydrodynamic interactions are taken into account in the virtual mass matrix and in the friction matrix of the assembly. An equation of motion is derived for the velocity of the geometric center of the assembly. The mean power is calculated as the mean rate of dissipation. The full range of viscosity is covered, so that the theory can be applied to the flying of birds, as well as to the swimming of fish or bacteria. As an example a system of three equal spheres moving along a common axis is studied.

  20. Superintegrability of geodesic motion on the sausage model

    NASA Astrophysics Data System (ADS)

    Arutyunov, Gleb; Heinze, Martin; Medina-Rincon, Daniel

    2017-06-01

    Reduction of the η-deformed sigma model on AdS_5× S5 to the two-dimensional squashed sphere (S^2)η can be viewed as a special case of the Fateev sausage model where the coupling constant ν is imaginary. We show that geodesic motion in this model is described by a certain superintegrable mechanical system with four-dimensional phase space. This is done by means of explicitly constructing three integrals of motion which satisfy the sl(2) Poisson algebra relations, albeit being non-polynomial in momenta. Further, we find a canonical transformation which transforms the Hamiltonian of this mechanical system to the one describing the geodesic motion on the usual two-sphere. By inverting this transformation we map geodesics on this auxiliary two-sphere back to the sausage model. This paper is a tribute to the memory of Prof Petr Kulish.

  1. Effect of inertia on laminar swimming and flying of an assembly of rigid spheres in an incompressible viscous fluid

    NASA Astrophysics Data System (ADS)

    Felderhof, B. U.

    2015-11-01

    A mechanical model of swimming and flying in an incompressible viscous fluid in the absence of gravity is studied on the basis of assumed equations of motion. The system is modeled as an assembly of rigid spheres subject to elastic direct interactions and to periodic actuating forces which sum to zero. Hydrodynamic interactions are taken into account in the virtual mass matrix and in the friction matrix of the assembly. An equation of motion is derived for the velocity of the geometric center of the assembly. The mean power is calculated as the mean rate of dissipation. The full range of viscosity is covered, so that the theory can be applied to the flying of birds, as well as to the swimming of fish or bacteria. As an example a system of three equal spheres moving along a common axis is studied.

  2. Diffusion and interactions of interstitials in hard-sphere interstitial solid solutions

    NASA Astrophysics Data System (ADS)

    van der Meer, Berend; Lathouwers, Emma; Smallenburg, Frank; Filion, Laura

    2017-12-01

    Using computer simulations, we study the dynamics and interactions of interstitial particles in hard-sphere interstitial solid solutions. We calculate the free-energy barriers associated with their diffusion for a range of size ratios and densities. By applying classical transition state theory to these free-energy barriers, we predict the diffusion coefficients, which we find to be in good agreement with diffusion coefficients as measured using event-driven molecular dynamics simulations. These results highlight that transition state theory can capture the interstitial dynamics in the hard-sphere model system. Additionally, we quantify the interactions between the interstitials. We find that, apart from excluded volume interactions, the interstitial-interstitial interactions are almost ideal in our system. Lastly, we show that the interstitial diffusivity can be inferred from the large-particle fluctuations alone, thus providing an empirical relationship between the large-particle fluctuations and the interstitial diffusivity.

  3. Application of time transfer functions to Gaia's global astrometry. Validation on DPAC simulated Gaia-like observations

    NASA Astrophysics Data System (ADS)

    Bertone, Stefano; Vecchiato, Alberto; Bucciarelli, Beatrice; Crosta, Mariateresa; Lattanzi, Mario G.; Bianchi, Luca; Angonin, Marie-Christine; Le Poncin-Lafitte, Christophe

    2017-12-01

    Context. A key objective of the ESA Gaia satellite is the realization of a quasi-inertial reference frame at visual wavelengths by means of global astrometric techniques. This requires accurate mathematical and numerical modeling of relativistic light propagation, as well as double-blind-like procedures for the internal validation of the results, before they are released to the scientific community at large. Aims: We aim to specialize the time transfer functions (TTF) formalism to the case of the Gaia observer and prove its applicability to the task of global sphere reconstruction (GSR), in anticipation of its inclusion in the GSR system, already featuring the Relativistic Astrometric MODel (RAMOD) suite, as an additional semi-external validation of the forthcoming Gaia baseline astrometric solutions. Methods: We extended the current GSR framework and software infrastructure (GSR2) to include TTF relativistic observation equations compatible with Gaia's operations. We used simulated data generated by the Gaia Data Processing and Analysis Consortium (DPAC) to obtain different least-squares estimations of the full (five-parameter) stellar spheres and gauge results. These were compared to analogous solutions obtained with the current RAMOD model in GSR2 (RAMOD@GSR2) and to the catalog generated with the Gaia RElativistic Model (GREM), the model baselined for Gaia and used to generate the DPAC synthetic data. Results: Linearized least-squares TTF solutions are based on spheres of about 132 000 primary stars uniformly distributed on the sky and simulated observations spanning the entire 5 yr range of Gaia's nominal operational lifetime. The statistical properties of the results compare well with those of GREM. Finally, comparisons to RAMOD@GSR2 solutions confirmed the known lower accuracy of that model and allowed us to establish firm limits on the quality of the linearization point outside of which an iteration for non-linearity is required for its proper convergence. This has proved invaluable as RAMOD@GSR2 is prepared to go into operations on real satellite data.

  4. Theory of adsorption in a polydisperse templated porous material: Hard sphere systems

    NASA Astrophysics Data System (ADS)

    RŻysko, Wojciech; Sokołowski, Stefan; Pizio, Orest

    2002-03-01

    A theoretical description of adsorption in a templated porous material, formed by an equilibrium quench of a polydisperse fluid composed of matrix and template particles and subsequent removal of the template particles is presented. The approach is based on the solution of the replica Ornstein-Zernike equations with Percus-Yevick and hypernetted chain closures. The method of solution uses expansions of size-dependent correlation functions into Fourier series, as described by Lado [J. Chem. Phys. 108, 6441 (1998)]. Specific calculations have been carried out for model systems, composed of hard spheres.

  5. Absolute quantum yield measurement of powder samples.

    PubMed

    Moreno, Luis A

    2012-05-12

    Measurement of fluorescence quantum yield has become an important tool in the search for new solutions in the development, evaluation, quality control and research of illumination, AV equipment, organic EL material, films, filters and fluorescent probes for bio-industry. Quantum yield is calculated as the ratio of the number of photons absorbed, to the number of photons emitted by a material. The higher the quantum yield, the better the efficiency of the fluorescent material. For the measurements featured in this video, we will use the Hitachi F-7000 fluorescence spectrophotometer equipped with the Quantum Yield measuring accessory and Report Generator program. All the information provided applies to this system. Measurement of quantum yield in powder samples is performed following these steps: 1. Generation of instrument correction factors for the excitation and emission monochromators. This is an important requirement for the correct measurement of quantum yield. It has been performed in advance for the full measurement range of the instrument and will not be shown in this video due to time limitations. 2. Measurement of integrating sphere correction factors. The purpose of this step is to take into consideration reflectivity characteristics of the integrating sphere used for the measurements. 3. Reference and Sample measurement using direct excitation and indirect excitation. 4. Quantum Yield calculation using Direct and Indirect excitation. Direct excitation is when the sample is facing directly the excitation beam, which would be the normal measurement setup. However, because we use an integrating sphere, a portion of the emitted photons resulting from the sample fluorescence are reflected by the integrating sphere and will re-excite the sample, so we need to take into consideration indirect excitation. This is accomplished by measuring the sample placed in the port facing the emission monochromator, calculating indirect quantum yield and correcting the direct quantum yield calculation. 5. Corrected quantum yield calculation. 6. Chromaticity coordinates calculation using Report Generator program. The Hitachi F-7000 Quantum Yield Measurement System offer advantages for this application, as follows: High sensitivity (S/N ratio 800 or better RMS). Signal is the Raman band of water measured under the following conditions: Ex wavelength 350 nm, band pass Ex and Em 5 nm, response 2 sec), noise is measured at the maximum of the Raman peak. High sensitivity allows measurement of samples even with low quantum yield. Using this system we have measured quantum yields as low as 0.1 for a sample of salicylic acid and as high as 0.8 for a sample of magnesium tungstate. Highly accurate measurement with a dynamic range of 6 orders of magnitude allows for measurements of both sharp scattering peaks with high intensity, as well as broad fluorescence peaks of low intensity under the same conditions. High measuring throughput and reduced light exposure to the sample, due to a high scanning speed of up to 60,000 nm/minute and automatic shutter function. Measurement of quantum yield over a wide wavelength range from 240 to 800 nm. Accurate quantum yield measurements are the result of collecting instrument spectral response and integrating sphere correction factors before measuring the sample. Large selection of calculated parameters provided by dedicated and easy to use software. During this video we will measure sodium salicylate in powder form which is known to have a quantum yield value of 0.4 to 0.5.

  6. LoCoH: Non-parameteric kernel methods for constructing home ranges and utilization distributions

    USGS Publications Warehouse

    Getz, Wayne M.; Fortmann-Roe, Scott; Cross, Paul C.; Lyons, Andrew J.; Ryan, Sadie J.; Wilmers, Christopher C.

    2007-01-01

    Parametric kernel methods currently dominate the literature regarding the construction of animal home ranges (HRs) and utilization distributions (UDs). These methods frequently fail to capture the kinds of hard boundaries common to many natural systems. Recently a local convex hull (LoCoH) nonparametric kernel method, which generalizes the minimum convex polygon (MCP) method, was shown to be more appropriate than parametric kernel methods for constructing HRs and UDs, because of its ability to identify hard boundaries (e.g., rivers, cliff edges) and convergence to the true distribution as sample size increases. Here we extend the LoCoH in two ways: ‘‘fixed sphere-of-influence,’’ or r -LoCoH (kernels constructed from all points within a fixed radius r of each reference point), and an ‘‘adaptive sphere-of-influence,’’ or a -LoCoH (kernels constructed from all points within a radius a such that the distances of all points within the radius to the reference point sum to a value less than or equal to a ), and compare them to the original ‘‘fixed-number-of-points,’’ or k -LoCoH (all kernels constructed from k -1 nearest neighbors of root points). We also compare these nonparametric LoCoH to parametric kernel methods using manufactured data and data collected from GPS collars on African buffalo in the Kruger National Park, South Africa. Our results demonstrate that LoCoH methods are superior to parametric kernel methods in estimating areas used by animals, excluding unused areas (holes) and, generally, in constructing UDs and HRs arising from the movement of animals influenced by hard boundaries and irregular structures (e.g., rocky outcrops). We also demonstrate that a -LoCoH is generally superior to k - and r -LoCoH (with software for all three methods available at http://locoh.cnr.berkeley.edu).

  7. Metal Alloy ICF Capsules Created by Electrodeposition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horwood, Corie; Stadermann, Michael; Bunn, Thomas L.

    Electrochemical deposition is an attractive alternative to physical vapor deposition and micromachining to produce metal capsules for inertial confinement fusion (ICF). Electrochemical deposition (also referred to as electrodeposition or plating) is expected to produce full-density metal capsules without seams or inclusions of unwanted atomic constituents, the current shortcomings of micromachine and physical vapor deposition, respectively. In this paper, we discuss new cathode designs that allow for the rapid electrodeposition of gold and copper alloys on spherical mandrels by making transient contact with the constantly moving spheres. Electrodeposition of pure gold, copper, platinum, and alloys of gold-copper and gold-silver are demonstrated,more » with nonporous coatings of >40 µm achieved in only a few hours of plating. The surface roughness of the spheres after electrodeposition is comparable to the starting mandrel, and the coatings appear to be fully dense with no inclusions. A detailed understanding of the electrodeposition conditions that result in different alloy compositions and plating rates will allow for the electrodeposition of graded alloys on spheres in the near future. Finally, this report on the electrodeposition of metals on spherical mandrels is an important first step toward the fabrication of graded-density metal capsules for ICF experiments at the National Ignition Facility.« less

  8. Synthesis, structure, spectroscopic and electrochemical properties of (2-amino-4-methylpyrimidine)-(pyridine-2,6-dicarboxylato)copper(II) monohydrate

    NASA Astrophysics Data System (ADS)

    Uçar, İbrahim; Karabulut, Bünyamin; Bulut, Ahmet; Büyükgüngör, Orhan

    2007-05-01

    The (2-amino-4-methylpyrimidine)-(pyridine-2,6-dicarboxylato)copper(II) monohydrate complex was synthesized and characterized by spectroscopic (IR, UV/Vis, EPR), thermal (TG/DTA) and electrochemical methods. X-ray structural analysis of the title complex revealed that the copper ion can be considered to have two coordination spheres. In the first coordination sphere the copper ion forms distorted square-planar geometry with trans-N 2O 2 donor set, and also the metal ion is weakly bonded to the amino-nitrogen in the layer over and to the carboxylic oxygen in the layer underneath in the second coordination sphere. The second coordination environment on the copper ion is attributed to pseudo octahedron. The powder EPR spectra of Cu(II) complex at room and liquid nitrogen temperature were recorded. The calculated g and A parameters have indicated that the paramagnetic centre is axially symmetric. The molecular orbital bond coefficients of the Cu(II) ion in d 9 state is also calculated by using EPR and optical absorption parameters. The cyclic voltammogram of the title complex investigated in DMSO (dimethylsulfoxide) solution exhibits only metal centered electroactivity in the potential range -1.25 to 1.5 V versus Ag/AgCl reference electrode.

  9. Metal Alloy ICF Capsules Created by Electrodeposition

    DOE PAGES

    Horwood, Corie; Stadermann, Michael; Bunn, Thomas L.

    2017-12-04

    Electrochemical deposition is an attractive alternative to physical vapor deposition and micromachining to produce metal capsules for inertial confinement fusion (ICF). Electrochemical deposition (also referred to as electrodeposition or plating) is expected to produce full-density metal capsules without seams or inclusions of unwanted atomic constituents, the current shortcomings of micromachine and physical vapor deposition, respectively. In this paper, we discuss new cathode designs that allow for the rapid electrodeposition of gold and copper alloys on spherical mandrels by making transient contact with the constantly moving spheres. Electrodeposition of pure gold, copper, platinum, and alloys of gold-copper and gold-silver are demonstrated,more » with nonporous coatings of >40 µm achieved in only a few hours of plating. The surface roughness of the spheres after electrodeposition is comparable to the starting mandrel, and the coatings appear to be fully dense with no inclusions. A detailed understanding of the electrodeposition conditions that result in different alloy compositions and plating rates will allow for the electrodeposition of graded alloys on spheres in the near future. Finally, this report on the electrodeposition of metals on spherical mandrels is an important first step toward the fabrication of graded-density metal capsules for ICF experiments at the National Ignition Facility.« less

  10. Theoretical calculation of the melting curve of Cu-Zr binary alloys

    DOE PAGES

    Gunawardana, K. G.S.H.; Wilson, S. R.; Mendelev, M. I.; ...

    2014-11-14

    Helmholtz free energies of the dominant binary crystalline solids found in the Cu-Zr system at high temperatures close to the melting curve are calculated. This theoretical approach combines fundamental measure density functional theory (applied to the hard-sphere reference system) and a perturbative approach to include the attractive interactions. The studied crystalline solids are Cu(fcc), Cu 51Zr 14(β), CuZr(B 2), CuZr 2(C11b), Zr(hcp), and Zr(bcc). The calculated Helmholtz free energies of crystalline solids are in good agreement with results from molecular-dynamics (MD) simulations. Using the same perturbation approach, the liquid phase free energies are calculated as a function of composition andmore » temperature, from which the melting curve of the entire composition range of this system can be obtained. Phase diagrams are determined in this way for two leading embedded atom method potentials, and the results are compared with experimental data. Furthermore, theoretical melting temperatures are compared both with experimental values and with values obtained directly from MD simulations at several compositions.« less

  11. A family of solutions to the Einstein-Maxwell system of equations describing relativistic charged fluid spheres

    NASA Astrophysics Data System (ADS)

    Komathiraj, K.; Sharma, Ranjan

    2018-05-01

    In this paper, we present a formalism to generate a family of interior solutions to the Einstein-Maxwell system of equations for a spherically symmetric relativistic charged fluid sphere matched to the exterior Reissner-Nordström space-time. By reducing the Einstein-Maxwell system to a recurrence relation with variable rational coefficients, we show that it is possible to obtain closed-form solutions for a specific range of model parameters. A large class of solutions obtained previously are shown to be contained in our general class of solutions. We also analyse the physical viability of our new class of solutions.

  12. Semiconductor laser insert with uniform illumination for use in photodynamic therapy

    NASA Astrophysics Data System (ADS)

    Charamisinau, Ivan; Happawana, Gemunu; Evans, Gary; Rosen, Arye; Hsi, Richard A.; Bour, David

    2005-08-01

    A low-cost semiconductor red laser light delivery system for esophagus cancer treatment is presented. The system is small enough for insertion into the patient's body. Scattering elements with nanoscale particles are used to achieve uniform illumination. The scattering element optimization calculations, with Mie theory, provide scattering and absorption efficiency factors for scattering particles composed of various materials. The possibility of using randomly deformed spheres and composite particles instead of perfect spheres is analyzed using an extension to Mie theory. The measured radiation pattern from a prototype light delivery system fabricated using these design criteria shows reasonable agreement with the theoretically predicted pattern.

  13. The Coulomb problem on a 3-sphere and Heun polynomials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bellucci, Stefano; Yeghikyan, Vahagn; Yerevan State University, Alex-Manoogian st. 1, 00025 Yerevan

    2013-08-15

    The paper studies the quantum mechanical Coulomb problem on a 3-sphere. We present a special parametrization of the ellipto-spheroidal coordinate system suitable for the separation of variables. After quantization we get the explicit form of the spectrum and present an algebraic equation for the eigenvalues of the Runge-Lentz vector. We also present the wave functions expressed via Heun polynomials.

  14. Planetary Education and Outreach Using the NOAA Science on a Sphere

    NASA Technical Reports Server (NTRS)

    Simon-Miller, A. A.; Williams, D. R.; Smith, S. M.; Friedlander, J. S.; Mayo, L. A.; Clark, P. E.; Henderson, M. A.

    2011-01-01

    Science On a Sphere (SOS) is a large visualization system, developed by the National Oceanic and Atmospheric Administration (NOAH), that uses computers running Redhat Linux and four video projectors to display animated data onto the outside of a sphere. Said another way, SOS is a stationary globe that can show dynamic, animated images in spherical form. Visualization of cylindrical data maps show planets, their atmosphere, oceans, and land, in very realistic form. The SOS system uses 4 video projectors to display images onto the sphere. Each projector is driven by a separate computer, and a fifth computer is used to control the operation of the display computers. Each computer is a relatively powerful PC with a high-end graphics card. The video projectors have native XGA resolution. The projectors are placed at the corners of a 30' x 30' square with a 68" carbon fiber sphere suspended in the center of the square. The equator of the sphere is typically located 86" off the floor. SOS uses common image formats such as JPEG, or TIFF in a very specific, but simple form; the images are plotted on an equatorial cylindrical equidistant projection, or as it is commonly known, a latitude/longitude grid, where the image is twice as wide as it is high (rectangular). 2048x] 024 is the minimum usable spatial resolution without some noticeable pixelation. Labels and text can be applied within the image, or using a timestamp-like feature within the SOS system software. There are two basic modes of operation for SOS: displaying a single image or an animated sequence of frames. The frame or frames can be setup to rotate or tilt, as in a planetary rotation. Sequences of images that animate through time produce a movie visualization, with or without an overlain soundtrack. After the images are processed, SOS will display the images in sequence and play them like a movie across the entire sphere surface. Movies can be of any arbitrary length, limited mainly by disk space and can be animated at frame rates up to 30 frames per second. Transitions, special effects, and other computer graphics techniques can be added to a sequence through the use of off-the-shelf software, like Final Cut Pro. However, one drawback is that the Sphere cannot be used in the same manner as a flat movie screen; images cannot be pushed to a "side", a highlighted area must be viewable to all sides of the room simultaneously, and some transitions do not work as well as others. We discuss these issues and workarounds in our poster.

  15. Statistical Analyses of Hydrophobic Interactions: A Mini-Review

    DOE PAGES

    Pratt, Lawrence R.; Chaudhari, Mangesh I.; Rempe, Susan B.

    2016-07-14

    Here this review focuses on the striking recent progress in solving for hydrophobic interactions between small inert molecules. We discuss several new understandings. First, the inverse temperature phenomenology of hydrophobic interactions, i.e., strengthening of hydrophobic bonds with increasing temperature, is decisively exhibited by hydrophobic interactions between atomic-scale hard sphere solutes in water. Second, inclusion of attractive interactions associated with atomic-size hydrophobic reference cases leads to substantial, nontrivial corrections to reference results for purely repulsive solutes. Hydrophobic bonds are weakened by adding solute dispersion forces to treatment of reference cases. The classic statistical mechanical theory for those corrections is not accuratemore » in this application, but molecular quasi-chemical theory shows promise. Lastly, because of the masking roles of excluded volume and attractive interactions, comparisons that do not discriminate the different possibilities face an interpretive danger.« less

  16. [Topical issues of biological safety under current conditions. Part 3. Scientific provision for the national regulation of the biological safety framework in its broad interpretation].

    PubMed

    Onishchenko, G G; Smolensky, V Yu; Ezhlova, E B; Demina, Yu V; Toporkov, V P; Toporkov, A V; Lyapin, M N; Kutyrev, V V

    2014-01-01

    Consequent of investigation concerned with biological safety (BS) framework development in its broad interpretation, reflected in the Russian Federation State Acts, identified have been conceptual entity parameters of the up-to-date broad interpretation of BS, which have formed a part of the developed by the authors system for surveillance (prophylaxis, localization, indication, identification, and diagnostics) and control (prophylaxis, localization, and response/elimination) over the emergency situations of biological (sanitary-epidemiological) character. The System functionality is activated through supplying the content with information data which are concerned with monitoring and control of specific internal and external threats in the sphere of BS provision fixed in the Supplement 2 of the International Health Regulations (IHR, 2005), and with the previously characterized nomenclature of hazardous biological factors. The system is designed as a network-based research-and-practice tool for evaluation of the situation in the sphere of BS provision, as well as assessment of efficacy of management decision making as regards BS control and proper State policy implementation. Most of the system elements either directly or indirectly relate to the scope of activities conducted by Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare, being substantial argument for allocating coordination functions in the sphere of BS provision to this government agency and consistent with its function as the State Coordinator on IHR (2005). The data collected serve as materials to Draft Federal Law "Concerning biological safety provision of the population".

  17. SPHERES: Design of a Formation Flying Testbed for ISS

    NASA Astrophysics Data System (ADS)

    Sell, S. W.; Chen, S. E.

    2002-01-01

    The SPHERES (Synchronized Position Hold Engage and Reorient Experimental Satellites) payload is an innovative formation-flying spacecraft testbed currently being developed for use internally aboard the International Space Station (ISS). The purpose of the testbed is to provide a cost-effective, long duration, replenishable, and easily reconfigurable platform with representative dynamics for the development and validation of metrology, formation flying, and autonomy algorithms. The testbed components consist of three 8-inch diameter free-flying "satellites," five ultrasound beacons, and an ISS laptop workstation. Each satellite is self-contained with on-board battery power, cold-gas propulsion (CO2), and processing systems. Satellites use two packs of eight standard AA batteries for approximately 90 minutes of lifetime while beacons last the duration of the mission powered by a single AA battery. The propulsion system uses pressurized carbon dioxide gas, stored in replaceable tanks, distributed through an adjustable regulator and associated tubing to twelve thrusters located on the faces of the satellites. A Texas Instruments C6701 DSP handles control algorithm data while an FPGA manages all sensor data, timing, and communication processes on the satellite. All three satellites communicate with each other and with the controlling laptop via a wireless RF link. Five ultrasound beacons, located around a predetermined work area, transmit ultrasound signals that are received by each satellite. The system effectively acts as a pseudo-GPS system, allowing the satellites to determine position and attitude and to navigate within the test arena. The payload hardware are predominantly Commercial Off The Shelf (COTS) products with the exception of custom electronics boards, selected propulsion system adaptors, and beacon and satellite structural elements. Operationally, SPHERES will run in short duration test sessions with approximately two weeks between each session. During operations, satellites will autonomously perform various maneuvers with one to three satellites operating simultaneously, involving a crew member only to upload protocols and replace satellite consumables (gas and power) during the test session. Once completed, data will be downlinked to the ground for analysis by the SPHERES team, facilitating the iterative process of new and/or modified protocols being uplinked for use in the next test session. SPHERES has prior flight experience on the NASA KC-135 Reduced Gravity aircraft and has also been in constant use in laboratory air table testing for almost two years. Slated for launch to the International Space Station on ISS12A.1, SPHERES will use its six-month flight to conduct risk-reduction investigations involving the coordinated motion of multiple satellites in a micro-gravity environment.

  18. Parental share in public and domestic spheres: a population study on gender equality, death, and sickness.

    PubMed

    Månsdotter, Anna; Lindholm, Lars; Lundberg, Michael; Winkvist, Anna; Ohman, Ann

    2006-07-01

    Examine the relation between aspects of gender equality and population health based on the premise that sex differences in health are mainly caused by the gender system. All Swedish couples (98 240 people) who had their first child together in 1978. The exposure of gender equality is shown by the parents' division of income and occupational position (public sphere), and parental leave and temporary child care (domestic sphere). People were classified by these indicators during 1978-1980 into different categories; those on an equal footing with their partner and those who were traditionally or untraditionally unequal. Health is measured by the outcomes of death during 1981-2001 and sickness absence during 1986-2000. Data are obtained by linking individual information from various national sources. The statistical method used is multiple logistic regressions with odds ratios as estimates of relative risks. From the public sphere is shown that traditionally unequal women have decreased health risks compared with equal women, while traditionally unequal men tend to have increased health risks compared with equal men. From the domestic sphere is indicated that both women and men run higher risks of death and sickness when being traditionally unequal compared with equal. Understanding the relation between gender equality and health, which was found to depend on sex, life sphere, and inequality type, seems to require a combination of the hypotheses of convergence, stress and expansion.

  19. SPHERES and Astrobee: Space Station Robotic Free Flyers

    NASA Technical Reports Server (NTRS)

    Benavides, Jose V.

    2017-01-01

    Free-flying space robots can be used when humans are present to off-load routine work, to increase astronaut productivity, and to handle contingencies. The International Space Station (ISS), for example, is a continuously manned orbital laboratory the size of a large house, which contains many thousands of inventory items and hundreds of diverse payloads and experiments - all of which have to be managed by 6 person crew. To help with this, NASA is developing and testing robotic free-flyers on the ISS. SPHERES (Synchronized Position Hold, Engage, Reorient, Experimental Satellites) is an ISS facility with three nano-satellites designed to research estimation, control, and autonomy algorithms. SPHERES are volleyball-sized, have their own power, propulsion and navigation systems, and work on the ISS under astronaut supervision. For more than 10 years, NASA has made SPHERES available to other U.S. government agencies, schools, commercial companies and students as a platform for science, technology development, and education. SPHERES will soon be succeeded by the new Astrobee free-flying robot. Astrobee builds on the success of SPHERES, but in addition to research, the robot will also be used for housekeeping and monitoring duties without astronaut supervision. Astrobee makes extensive use of open-source (the complete software stack is available on GitHub) and is scheduled to be installed on the ISS in late Spring 2018.

  20. Elastic response of binary hard-sphere fluids

    NASA Astrophysics Data System (ADS)

    Rickman, J. M.; Ou-Yang, H. Daniel

    2011-07-01

    We derive expressions for the high-frequency, wave-number-dependent elastic constants of a binary hard-sphere fluid and employ Monte Carlo computer simulation to evaluate these constants in order to highlight the impact of composition and relative sphere diameter on the elastic response of this system. It is found that the elastic constant c11(k) exhibits oscillatory behavior as a function of k whereas the high-frequency shear modulus, for example, does not. This behavior is shown to be dictated by the angular dependence (in k⃗ space) of derivatives of the interatomic force at contact. The results are related to recent measurements of the compressibility of colloidal fluids in laser trapping experiments.

  1. Orthogonality of spherical harmonic coefficients

    NASA Astrophysics Data System (ADS)

    McLeod, M. G.

    1980-08-01

    Orthogonality relations are obtained for the spherical harmonic coefficients of functions defined on the surface of a sphere. Following a brief discussion of the orthogonality of Fourier series coefficients, consideration is given to the values averaged over all orientations of the coordinate system of the spherical harmonic coefficients of a function defined on the surface of a sphere that can be expressed in terms of Legendre polynomials for the special case where the function is the sum of two delta functions located at two different points on the sphere, and for the case of an essentially arbitrary function. It is noted that the orthogonality relations derived have found applications in statistical studies of the geomagnetic field.

  2. The Heat and Mass Transfer Processes at the Cooling of Strong Heated Sphere in a Cold Liquid

    NASA Astrophysics Data System (ADS)

    Puzina, Yu Yu

    2017-10-01

    Some new experimental results of continuum mechanics problems in two-phase systems are described. The processes of heat and mass transfer during cooling of strong heated sphere in the subcooled liquid are studied. Due to high level of heater temperature the stable vapor film is formed on the sphere surface. Calculation of steady-state transport processes at vapor - water interface is carried out using methods of molecular-kinetic theory. Heat transfer in vapor by thermal conductivity and natural convection in liquid are considered. Pressure balance is provided by hydrostatic pressure and non-equilibrium boundary condition. The results of the calculations are analyzed by comparison with previous data and experimental results.

  3. The astysphere and urban geochemistry-a new approach to integrate urban systems into the geoscientific concept of spheres and a challenging concept of modern geochemistry supporting the sustainable development of planet earth.

    PubMed

    Norra, Stefan

    2009-07-01

    In 1875, the geoscientist Walter Suess introduced several spheres, such as the lithosphere and the atmosphere to promote a comprehensive understanding of the system earth. Since then, this idea became the dominating concept for the understanding of the distribution of chemical elements in the system earth. Meanwhile, due to the importance of human beings on global element fluxes, the term anthroposphere was introduced. Nevertheless, in face of the ongoing urbanization of the earth, this concept is not any more adequate enough to develop a comprehensive understanding of global element fluxes in and between solid, liquid, and gaseous phases. This article discusses a new concept integrating urbanization into the geoscientific concept of spheres. No geological exogenic force has altered the earth's surface during the last centuries in such an extent as human activity. Humans have altered the morphology and element balances of the earth by establishing agrosystems first and urban systems later. Currently, urban systems happen to become the main regulators for fluxes of many elements on a global scale due to ongoing industrial and economic development and a growing number of inhabitants. Additionally, urban systems are constantly expanding and cover more and more former natural and agricultural areas. For nature, urban systems are new phenomena, which never existed in previous geological eras. The process of the globe's urbanization concurrently is active with the global climate change. In fact, urban systems are a major emitter for climate active gases. Thus, beside the global changes in economy and society, urbanization is an important factor within the global change of nature as is already accepted for climate, ecosystems, and biodiversity. Due to the fact that urbanization has become a global process shaping the earth and that the urban systems are globally cross-linked among each other, a new geoscientific sphere has to be introduced: the astysphere. This sphere comprises the parts of the earth influenced by urban systems. Accepting urbanization as global ongoing process forming the astysphere comprehensively copes with the growing importance of urbanization on the creation of present geologic formations. Anthropogenic activities occur mainly in rural and urban environments. For long lasting periods of human history, human activities mainly were focused on hunting and agriculture, but since industrialization, urbanized areas became increasingly important for the material and energy fluxes of earth. Thus, it seems appropriate to classify the anthroposphere into an agriculturally and an urban-dominated sphere, which are the agrosphere (Krishna 2003) and the astysphere (introduced by Norra 2007). We have to realize that urban systems are deposits, consumers, and transformers of resources interacting among each other and forming a network around the globe. Since the future of human mankind depends on the sustainable use of available resources, only a global and holistic view of the cross-linked urban systems forming together the astysphere provide the necessary geoscientific background understanding for global urban material and energy fluxes. If we want to ensure worth-living conditions for future generations of mankind, we have to develop global models of the future needs for resources by the global metasystem of urban systems, called astysphere. The final vision for geoscientific research on the astysphere must be to design models describing the global process of urbanization of the earth and the development of the astysphere with respect to fluxes of materials, elements, and energy as well as with respect to the forming of the earth's face. Besides that, just from the viewpoint of fundamental research, the geoscientific concept of spheres has to be complemented by the astysphere if this concept shall fully represent the system earth.

  4. Asymptotic orderings and approximations of the Master kinetic equation for large hard spheres systems

    NASA Astrophysics Data System (ADS)

    Tessarotto, Massimo; Asci, Claudio

    2017-05-01

    In this paper the problem is posed of determining the physically-meaningful asymptotic orderings holding for the statistical description of a large N-body system of hard spheres, i.e., formed by N ≡1/ε ≫ 1 particles, which are allowed to undergo instantaneous and purely elastic unary, binary or multiple collisions. Starting point is the axiomatic treatment recently developed [Tessarotto et al., 2013-2016] and the related discovery of an exact kinetic equation realized by Master equation which advances in time the 1-body probability density function (PDF) for such a system. As shown in the paper the task involves introducing appropriate asymptotic orderings in terms of ε for all the physically-relevant parameters. The goal is that of identifying the relevant physically-meaningful asymptotic approximations applicable for the Master kinetic equation, together with their possible relationships with the Boltzmann and Enskog kinetic equations, and holding in appropriate asymptotic regimes. These correspond either to dilute or dense systems and are formed either by small-size or finite-size identical hard spheres, the distinction between the various cases depending on suitable asymptotic orderings in terms of ε.

  5. Nonequilibrium thermodynamics in sheared hard-sphere materials.

    PubMed

    Lieou, Charles K C; Langer, J S

    2012-06-01

    We combine the shear-transformation-zone (STZ) theory of amorphous plasticity with Edwards' statistical theory of granular materials to describe shear flow in a disordered system of thermalized hard spheres. The equations of motion for this system are developed within a statistical thermodynamic framework analogous to that which has been used in the analysis of molecular glasses. For hard spheres, the system volume V replaces the internal energy U as a function of entropy S in conventional statistical mechanics. In place of the effective temperature, the compactivity X=∂V/∂S characterizes the internal state of disorder. We derive the STZ equations of motion for a granular material accordingly, and predict the strain rate as a function of the ratio of the shear stress to the pressure for different values of a dimensionless, temperature-like variable near a jamming transition. We use a simplified version of our theory to interpret numerical simulations by Haxton, Schmiedeberg, and Liu, and in this way are able to obtain useful insights about internal rate factors and relations between jamming and glass transitions.

  6. Emergent interparticle interactions in thermal amorphous solids

    NASA Astrophysics Data System (ADS)

    Gendelman, Oleg; Lerner, Edan; Pollack, Yoav G.; Procaccia, Itamar; Rainone, Corrado; Riechers, Birte

    2016-11-01

    Amorphous media at finite temperatures, be them liquids, colloids, or glasses, are made of interacting particles that move chaotically due to thermal energy, continuously colliding and scattering off each other. When the average configuration in these systems relaxes only at long times, one can introduce effective interactions that keep the mean positions in mechanical equilibrium. We introduce a framework to determine the effective force laws that define an effective Hessian that can be employed to discuss stability properties and the density of states of the amorphous system. We exemplify the approach with a thermal glass of hard spheres; these experience zero forces when not in contact and infinite forces when they touch. Close to jamming we recapture the effective interactions that at temperature T depend on the gap h between spheres as T /h [C. Brito and M. Wyart, Europhys. Lett. 76, 149 (2006), 10.1209/epl/i2006-10238-x]. For hard spheres at lower densities or for systems whose binary bare interactions are longer ranged (at any density), the emergent force laws include ternary, quaternary, and generally higher-order many-body terms, leading to a temperature-dependent effective Hessian.

  7. Population annealing simulations of a binary hard-sphere mixture

    NASA Astrophysics Data System (ADS)

    Callaham, Jared; Machta, Jonathan

    2017-06-01

    Population annealing is a sequential Monte Carlo scheme well suited to simulating equilibrium states of systems with rough free energy landscapes. Here we use population annealing to study a binary mixture of hard spheres. Population annealing is a parallel version of simulated annealing with an extra resampling step that ensures that a population of replicas of the system represents the equilibrium ensemble at every packing fraction in an annealing schedule. The algorithm and its equilibration properties are described, and results are presented for a glass-forming fluid composed of a 50/50 mixture of hard spheres with diameter ratio of 1.4:1. For this system, we obtain precise results for the equation of state in the glassy regime up to packing fractions φ ≈0.60 and study deviations from the Boublik-Mansoori-Carnahan-Starling-Leland equation of state. For higher packing fractions, the algorithm falls out of equilibrium and a free volume fit predicts jamming at packing fraction φ ≈0.667 . We conclude that population annealing is an effective tool for studying equilibrium glassy fluids and the jamming transition.

  8. Spiral Ganglion Stem Cells Can Be Propagated and Differentiated Into Neurons and Glia

    PubMed Central

    Zecha, Veronika; Wagenblast, Jens; Arnhold, Stefan; Edge, Albert S. B.; Stöver, Timo

    2014-01-01

    Abstract The spiral ganglion is an essential functional component of the peripheral auditory system. Most types of hearing loss are associated with spiral ganglion cell degeneration which is irreversible due to the inner ear's lack of regenerative capacity. Recent studies revealed the existence of stem cells in the postnatal spiral ganglion, which gives rise to the hope that these cells might be useful for regenerative inner ear therapies. Here, we provide an in-depth analysis of sphere-forming stem cells isolated from the spiral ganglion of postnatal mice. We show that spiral ganglion spheres have characteristics similar to neurospheres isolated from the brain. Importantly, spiral ganglion sphere cells maintain their major stem cell characteristics after repeated propagation, which enables the culture of spheres for an extended period of time. In this work, we also demonstrate that differentiated sphere-derived cell populations not only adopt the immunophenotype of mature spiral ganglion cells but also develop distinct ultrastructural features of neurons and glial cells. Thus, our work provides further evidence that self-renewing spiral ganglion stem cells might serve as a promising source for the regeneration of lost auditory neurons. PMID:24940560

  9. Effective conductivity of suspensions of overlapping spheres

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, I.C.; Torquato, S.

    1992-03-15

    An accurate first-passage simulation technique formulated by the authors (J. Appl. Phys. {bold 68}, 3892 (1990)) is employed to compute the effective conductivity {sigma}{sub {ital e}} of distributions of penetrable (or overlapping) spheres of conductivity {sigma}{sub 2} in a matrix of conductivity {sigma}{sub 1}. Clustering of particles in this model results in a generally intricate topology for virtually the entire range of sphere volume fractions {phi}{sub 2} (i.e., 0{le}{phi}{sub 2}{le}1). Results for the effective conductivity {sigma}{sub {ital e}} are presented for several values of the conductivity ratio {alpha}={sigma}{sub 2}/{sigma}{sub 1}, including superconducting spheres ({alpha}={infinity}) and perfectly insulating spheres ({alpha}=0), andmore » for a wide range of volume fractions. The data are shown to lie between rigorous three-point bounds on {sigma}{sub {ital e}} for the same model. Consistent with the general observations of Torquato (J. Appl. Phys. {bold 58}, 3790 (1985)) regarding the utility of rigorous bounds, one of the bounds provides a good estimate of the effective conductivity, even in the extreme contrast cases ({alpha}{much gt}1 or {alpha}{congruent}0), depending upon whether the system is below or above the percolation threshold.« less

  10. Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo

    PubMed Central

    Driskell, Ryan R; Juneja, Vikram R; Connelly, John T; Kretzschmar, Kai; Tan, David W -M; Watt, Fiona M

    2012-01-01

    In neonatal mouse skin, two types of dermal papilla (DP) are distinguished by Sox2 expression: CD133+Sox2+ DP are associated with guard/awl/auchene hairs, whereas CD133+Sox2− DP are associated with zigzag (ZZ) hairs. We describe a three-dimensional hydrogel culture system that supports clonal growth of CD133+Sox2+, CD133+Sox2−, and CD133−Sox2− (non-DP) neonatal dermal cells. All three cell populations formed spheres that expressed the DP markers alkaline phosphatase, α8 integrin, and CD133. Nevertheless, spheres formed by CD133− cells did not efficiently support hair follicle formation in skin reconstitution assays. In the presence of freshly isolated P2 dermal cells, CD133+Sox2+ and CD133+Sox2− spheres contributed to the DP of both AA and ZZ hairs. Hair type did not correlate with sphere size. Sox2 expression was maintained in culture, but not induced significantly in Sox2− cells in vitro or in vivo, suggesting that Sox2+ cells are a distinct cellular lineage. Although Sox2+ cells were least efficient at forming spheres, they had the greatest ability to contribute to DP and non-DP dermis in reconstituted skin. As the culture system supports clonal growth of DP cells and maintenance of distinct DP cell types, it will be useful for further analysis of intrinsic and extrinsic signals controlling DP function. PMID:22189784

  11. Performance analysis of sliding window filtering of two dimensional signals based on stream data processing systems

    NASA Astrophysics Data System (ADS)

    Kazanskiy, Nikolay; Protsenko, Vladimir; Serafimovich, Pavel

    2016-03-01

    This research article contains an experiment with implementation of image filtering task in Apache Storm and IBM InfoSphere Streams stream data processing systems. The aim of presented research is to show that new technologies could be effectively used for sliding window filtering of image sequences. The analysis of execution was focused on two parameters: throughput and memory consumption. Profiling was performed on CentOS operating systems running on two virtual machines for each system. The experiment results showed that IBM InfoSphere Streams has about 1.5 to 13.5 times lower memory footprint than Apache Storm, but could be about 2.0 to 2.5 slower on a real hardware.

  12. Welding at the Kennedy Space Center.

    NASA Technical Reports Server (NTRS)

    Clautice, W. E.

    1973-01-01

    Brief description of the nature of the mechanical equipment at a space launch complex from a welding viewpoint. including an identification of the major welding applications used in the construction of this complex. The role played by welding in the ground support equipment is noted, including the welded structures and systems required in the vehicle assembly building, the mobile launchers, transporters, mobile service structure, launch pad and launch site, the propellants system, the pneumatics system, and the environmental control system. The welding processes used at the Kennedy Space Center are reviewed, and a particularly detailed account is given of the design and fabrication of the liquid hydrogen and liquid oxygen storage spheres and piping. Finally, the various methods of testing and inspecting the storage spheres are cited.

  13. Selective encapsulation by Janus particles

    NASA Astrophysics Data System (ADS)

    Li, Wei; Ruth, Donovan; Gunton, James D.; Rickman, Jeffrey M.

    2015-06-01

    We employ Monte Carlo simulation to examine encapsulation in a system comprising Janus oblate spheroids and isotropic spheres. More specifically, the impact of variations in temperature, particle size, inter-particle interaction range, and strength is examined for a system in which the spheroids act as the encapsulating agents and the spheres as the encapsulated guests. In this picture, particle interactions are described by a quasi-square-well patch model. This study highlights the environmental adaptation and selectivity of the encapsulation system to changes in temperature and guest particle size, respectively. Moreover, we identify an important range in parameter space where encapsulation is favored, as summarized by an encapsulation map. Finally, we discuss the generalization of our results to systems having a wide range of particle geometries.

  14. The structure and properties of a simple model mixture of amphiphilic molecules and ions at a solid surface

    NASA Astrophysics Data System (ADS)

    Pizio, O.; Sokołowski, S.; Sokołowska, Z.

    2014-05-01

    We investigate microscopic structure, adsorption, and electric properties of a mixture that consists of amphiphilic molecules and charged hard spheres in contact with uncharged or charged solid surfaces. The amphiphilic molecules are modeled as spheres composed of attractive and repulsive parts. The electrolyte component of the mixture is considered in the framework of the restricted primitive model (RPM). The system is studied using a density functional theory that combines fundamental measure theory for hard sphere mixtures, weighted density approach for inhomogeneous charged hard spheres, and a mean-field approximation to describe anisotropic interactions. Our principal focus is in exploring the effects brought by the presence of ions on the distribution of amphiphilic particles at the wall, as well as the effects of amphiphilic molecules on the electric double layer formed at solid surface. In particular, we have found that under certain thermodynamic conditions a long-range translational and orientational order can develop. The presence of amphiphiles produces changes of the shape of the differential capacitance from symmetric or non-symmetric bell-like to camel-like. Moreover, for some systems the value of the potential of the zero charge is non-zero, in contrast to the RPM at a charged surface.

  15. Numerical Solution of Light Scattered from and Transmitted through a Rough Dielectric Surface with Applications to Periodic Roughness and Isolated Structures

    NASA Technical Reports Server (NTRS)

    Sun, Wenbo; Videnn, Gorden; Lin, Bing; Hu, Yongxiang

    2007-01-01

    Light scattering and transmission by rough surfaces are of considerable interest in a variety of applications including remote sensing and characterization of surfaces. In this work, the finite-difference time domain technique is applied to calculate the scattered and transmitted electromagnetic fields of an infinite periodic rough surface. The elements of Mueller matrix for scattered light are calculated by an integral of the near fields over a significant number of periods of the surface. The normalized Mueller matrix elements of the scattered light and the spatial distribution of the transmitted flux for a monolayer of micron-sized dielectric spheres on a silicon substrate are presented. The numerical results show that the nonzero Mueller matrix elements of the system of the monolayer of dielectric spheres on a silicon substrate have specific maxima at some scattering angles. These maxima may be used in characterization of the feature of the system. For light transmitted through the monolayer of spheres, our results show that the transmitted energy focuses around the ray passing through centers of the spheres. At other locations, the transmitted flux is very small. The technique also may be used to calculate the perturbance of the electromagnetic field due to the presence of an isolated structure on the substrate.

  16. Calibration of a flexible measurement system based on industrial articulated robot and structured light sensor

    NASA Astrophysics Data System (ADS)

    Mu, Nan; Wang, Kun; Xie, Zexiao; Ren, Ping

    2017-05-01

    To realize online rapid measurement for complex workpieces, a flexible measurement system based on an articulated industrial robot with a structured light sensor mounted on the end-effector is developed. A method for calibrating the system parameters is proposed in which the hand-eye transformation parameters and the robot kinematic parameters are synthesized in the calibration process. An initial hand-eye calibration is first performed using a standard sphere as the calibration target. By applying the modified complete and parametrically continuous method, we establish a synthesized kinematic model that combines the initial hand-eye transformation and distal link parameters as a whole with the sensor coordinate system as the tool frame. According to the synthesized kinematic model, an error model is constructed based on spheres' center-to-center distance errors. Consequently, the error model parameters can be identified in a calibration experiment using a three-standard-sphere target. Furthermore, the redundancy of error model parameters is eliminated to ensure the accuracy and robustness of the parameter identification. Calibration and measurement experiments are carried out based on an ER3A-C60 robot. The experimental results show that the proposed calibration method enjoys high measurement accuracy, and this efficient and flexible system is suitable for online measurement in industrial scenes.

  17. Chiral Structures of Thermoresponsive Soft Spheres in Hollow Cylinders

    NASA Astrophysics Data System (ADS)

    Lohr, Matthew A.; Alsayed, Ahmed; Zhang, Zexin; Yodh, Arjun G.

    2009-03-01

    We experimentally observe the formation of closely packed crystalline structures in hollow cylinders. The structures have varying degrees of chiral order. The systems are created from aqueous suspensions of thermoresponsive N-isopropylacrylamide (NIPA) microgel particles packed in micron-diameter glass capillaries. We categorize these structures according to classifications used by Erickson for tubular packings of hard spheres [1]. By varying the temperature-tunable diameter of these particles, the system's volume fraction is changed, permitting observations of the resilience of these structures and their melting transitions. Melting of these thermal crystalline structures is observed. [1] R. O. Erickson, Science 181 (1973) 705-716.

  18. Gas-liquid coexistence in a system of dipolar soft spheres.

    PubMed

    Jia, Ran; Braun, Heiko; Hentschke, Reinhard

    2010-12-01

    The existence of gas-liquid coexistence in dipolar fluids with no other contribution to attractive interaction than dipole-dipole interaction is a basic and open question in the theory of fluids. Here we compute the gas-liquid critical point in a system of dipolar soft spheres subject to an external electric field using molecular dynamics computer simulation. Tracking the critical point as the field strength is approaching zero we find the following limiting values: T(c)=0.063 and ρ(c)=0.0033 (dipole moment μ=1). These values are confirmed by independent simulation at zero field strength.

  19. Experimental stress analysis of large plastic deformations in a hollow sphere deformed by impact against a concrete block

    NASA Technical Reports Server (NTRS)

    Morris, R. E.

    1973-01-01

    An experimental plastic strain measurement system is presented for use on the surface of high velocity impact test models. The system was used on a hollow sphere tested in impact against a reinforced concrete block. True strains, deviatoric stresses, and true stresses were calculated from experimental measurements. The maximum strain measured in the model was small compared to the true failure strain obtained from static tensile tests of model material. This fact suggests that a much greater impact velocity would be required to cause failure of the model shell structure.

  20. A neutron spectrum unfolding computer code based on artificial neural networks

    NASA Astrophysics Data System (ADS)

    Ortiz-Rodríguez, J. M.; Reyes Alfaro, A.; Reyes Haro, A.; Cervantes Viramontes, J. M.; Vega-Carrillo, H. R.

    2014-02-01

    The Bonner Spheres Spectrometer consists of a thermal neutron sensor placed at the center of a number of moderating polyethylene spheres of different diameters. From the measured readings, information can be derived about the spectrum of the neutron field where measurements were made. Disadvantages of the Bonner system are the weight associated with each sphere and the need to sequentially irradiate the spheres, requiring long exposure periods. Provided a well-established response matrix and adequate irradiation conditions, the most delicate part of neutron spectrometry, is the unfolding process. The derivation of the spectral information is not simple because the unknown is not given directly as a result of the measurements. The drawbacks associated with traditional unfolding procedures have motivated the need of complementary approaches. Novel methods based on Artificial Intelligence, mainly Artificial Neural Networks, have been widely investigated. In this work, a neutron spectrum unfolding code based on neural nets technology is presented. This code is called Neutron Spectrometry and Dosimetry with Artificial Neural networks unfolding code that was designed in a graphical interface. The core of the code is an embedded neural network architecture previously optimized using the robust design of artificial neural networks methodology. The main features of the code are: easy to use, friendly and intuitive to the user. This code was designed for a Bonner Sphere System based on a 6LiI(Eu) neutron detector and a response matrix expressed in 60 energy bins taken from an International Atomic Energy Agency compilation. The main feature of the code is that as entrance data, for unfolding the neutron spectrum, only seven rate counts measured with seven Bonner spheres are required; simultaneously the code calculates 15 dosimetric quantities as well as the total flux for radiation protection purposes. This code generates a full report with all information of the unfolding in the HTML format. NSDann unfolding code is freely available, upon request to the authors.

  1. Satellite Data Assimilation within KIAPS-LETKF system

    NASA Astrophysics Data System (ADS)

    Jo, Y.; Lee, S., Sr.; Cho, K.

    2016-12-01

    Korea Institute of Atmospheric Prediction Systems (KIAPS) has been developing an ensemble data assimilation system using four-dimensional local ensemble transform kalman filter (LETKF; Hunt et al., 2007) within KIAPS Integrated Model (KIM), referred to as "KIAPS-LETKF". KIAPS-LETKF system was successfully evaluated with various Observing System Simulation Experiments (OSSEs) with NCAR Community Atmospheric Model - Spectral Element (Kang et al., 2013), which has fully unstructured quadrilateral meshes based on the cubed-sphere grid as the same grid system of KIM. Recently, assimilation of real observations has been conducted within the KIAPS-LETKF system with four-dimensional covariance functions over the 6-hr assimilation window. Then, conventional (e.g., sonde, aircraft, and surface) and satellite (e.g., AMSU-A, IASI, GPS-RO, and AMV) observations have been provided by the KIAPS Package for Observation Processing (KPOP). Wind speed prediction was found most beneficial due to ingestion of AMV and for the temperature prediction the improvement in assimilation is mostly due to ingestion of AMSU-A and IASI. However, some degradation in the simulation of the GPS-RO is presented in the upper stratosphere, even though GPS-RO leads positive impacts on the analysis and forecasts. We plan to test the bias correction method and several vertical localization strategies for radiance observations to improve analysis and forecast impacts.

  2. Scale Marking Method on the Circumference of Circle Elements for Astronomical Instruments in the Early Joseon Dynasty

    NASA Astrophysics Data System (ADS)

    Mihn, Byeong-Hee; Lee, Ki-Won; Ahn, Young Sook; Lee, Yong Sam

    2015-03-01

    During the reign of King Sejong (世宗, 1418-1450) in the Joseon Dynasty, there were lots of astronomical instruments, including miniaturized ones. Those instruments utilized the technical know-how acquired through building contemporary astronomical instruments previously developed in the Song(宋), Jin(金), and Yuan(元) dynasties of China. In those days, many astronomical instruments had circles, rings, and spheres carved with a scale of 365.25, 100, and 24 parts, respectively, on their circumference. These were called the celestial-circumference degree, hundred-interval (Baekgak), and 24 direction, respectively. These scales are marked by the angular distance, not by the angle. Therefore, these circles, rings, and spheres had to be optimized in size to accomodate proper scales. Assuming that the scale system is composed of integer multiples of unit length, we studied the sizes of circles by referring to old articles and investigating existing artifacts. We discovered that the star chart of Cheonsang yeolcha bunyajido was drawn with a royal standard ruler (周尺) based on the unit length of 207 mm. Interestingly, its circumference was marked by the unit scale of 3 puns per 1 du (or degree) like Honsang (a celestial globe). We also found that Hyeonju ilgu (a equatorial sundial) has a Baekgak disk on a scale of 1 pun per 1 gak (that is an interval of time similar to a quarter). This study contributes to the analysis of specifications of numerous circular elements from old Korean astronomical instruments.

  3. DIRECT IMAGING AND SPECTROSCOPY OF A YOUNG EXTRASOLAR KUIPER BELT IN THE NEAREST OB ASSOCIATION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Currie, Thayne; Lisse, Carey M.; Kuchner, Marc

    2015-07-01

    We describe the discovery of a bright, young Kuiper belt–like debris disk around HD 115600, a ∼1.4–1.5 M{sub ⊙}, ∼15 Myr old member of the Sco–Cen OB Association. Our H-band coronagraphy/integral field spectroscopy from the Gemini Planet Imager shows the ring has a (luminosity-scaled) semimajor axis of (∼22 AU) ∼ 48 AU, similar to the current Kuiper belt. The disk appears to have neutral-scattering dust, is eccentric (e ∼ 0.1–0.2), and could be sculpted by analogs to the outer solar system planets. Spectroscopy of the disk ansae reveal a slightly blue to gray disk color, consistent with major Kuiper beltmore » chemical constituents, where water ice is a very plausible dominant constituent. Besides being the first object discovered with the next generation of extreme adaptive optics systems (i.e., SCExAO, GPI, SPHERE), HD 115600's debris ring and planetary system provide a key reference point for the early evolution of the solar system, the structure, and composition of the Kuiper belt and the interaction between debris disks and planets.« less

  4. Small asteroids temporarily captured in the Earth-Moon system

    NASA Astrophysics Data System (ADS)

    Jedicke, Robert; Bolin, Bryce; Bottke, William F.; Chyba, Monique; Fedorets, Grigori; Granvik, Mikael; Patterson, Geoff

    2016-01-01

    We present an update on our work on understanding the population of natural objects that are temporarily captured in the Earth-Moon system like the 2-3 meter diameter, 2006 RH120, that was discovered by the Catalina Sky Survey. We use the term `minimoon' to refer to objects that are gravitationally bound to the Earth-Moon system, make at least one revolution around the barycenter in a co-rotating frame relative to the Earth-Sun axis, and are within 3 Earth Hill-sphere radii. There are one or two 1 to 2 meter diameter minimoons in the steady state population at any time, and about a dozen larger than 50 cm diameter. `Drifters' are also bound to the Earth-Moon system but make less than one revolution about the barycenter. The combined population of minimoons and drifters provide a new opportunity for scientific exploration of small asteroids and testing concepts for in-situ resource utilization. These objects provide interesting challenges for rendezvous missions because of their limited lifetime and complicated trajectories. Furthermore, they are difficult to detect because they are small, available for a limited time period, and move quickly across the sky.

  5. Small asteroids temporarily captured in the Earth-Moon system

    NASA Astrophysics Data System (ADS)

    Jedicke, Robert; Bolin, Bryce; Bottke, William F.; Chyba, Monique; Fedorets, Grigori; Granvik, Mikael; Patterson, Geoff

    2015-08-01

    We will present an update on our work on understanding the population of natural objects that are temporarily captured in the Earth-Moon system, such as the 2-3 meter diameter 2006 RH120 that was discovered by the Catalina Sky Survey. We use the term 'minimoon' to refer to objects that are gravitationally bound to the Earth-Moon system, make at least one revolution around the barycenter in a co-rotating frame relative to the Earth-Sun axis, and are within 3 Earth Hill-sphere radii. There are one or two 1 to 2 meter diameter minimoons in the steady state population at any time, and about a dozen larger than 50 cm diameter. `Drifters' are also bound to the Earth-Moon system but make less than one revolution about the barycenter. The combined population of minimoons and drifters provide a new opportunity for scientific exploration of small asteroids and testing concepts for in-situ resource utilization. These objects provide interesting challenges for rendezvous missions because of their limited lifetime and complicated trajectories. Furthermore, they are difficult to detect because they are small, available for a limited time period, and move quickly across the sky.

  6. Single-beam dielectric-microsphere trapping with optical heterodyne detection

    NASA Astrophysics Data System (ADS)

    Rider, Alexander D.; Blakemore, Charles P.; Gratta, Giorgio; Moore, David C.

    2018-01-01

    A technique to levitate and measure the three-dimensional position of micrometer-sized dielectric spheres with heterodyne detection is presented. The two radial degrees of freedom are measured by interfering light transmitted through the microsphere with a reference wavefront, while the axial degree of freedom is measured from the phase of the light reflected from the surface of the microsphere. This method pairs the simplicity and accessibility of single-beam optical traps to a measurement of displacement that is intrinsically calibrated by the wavelength of the trapping light and has exceptional immunity to stray light. A theoretical shot noise limit of 1.3 ×10-13 m /√{Hz } for the radial degrees of freedom, and 3.0 ×10-15 m /√{Hz } for the axial degree of freedom can be obtained in the system described. The measured acceleration noise in the radial direction is 7.5 ×10-5 (m /s2) /√{Hz } .

  7. Temperature dependent structural and vibrational properties of liquid indium

    NASA Astrophysics Data System (ADS)

    Patel, A. B.; Bhatt, N. K.

    2018-05-01

    The influence of the temperature effect on both the structure factor and the phonon dispersion relation of liquid indium have been investigated by means of pseudopotential theory. The Percus-Yevick Hard Sphere reference system is applied to describe the structural calculation. The effective electron-ion interaction is explained by using modified empty core potential due to Hasegawa et al. along with a local field correction function due to Ichimaru-Utsumi (IU). The temperature dependence of pair potential needed at higher temperatures was achieved by multiplying the damping factor exp(- π/kBT2k F r ) in the pair potential. Very close agreement of static structure factor, particularly, at elevated temperatures confirms the validity of the local potential. A positive dispersion is found in low-q region and the correct trend of phonon dispersion branches like the experimental; shows all broad features of collective excitations in liquid metals.

  8. Method and apparatus for producing gas-filled hollow spheres. [target pellets for inertial confinement fusion

    NASA Technical Reports Server (NTRS)

    Wang, T. G.; Elleman, D. D. (Inventor)

    1982-01-01

    A system for forming hollow spheres containing pressured gas is described which includes a cylinder device containing a molten solid material with a nozzle at its end. A second gas nozzle, lying slightly upstream from the tip of the first nozzle, is connected to a source that applies pressured filler gas that is to fill the hollow spheres. High pressure is applied to the molten metal, as by moving a piston within the cylinder device, to force the molten material out of the first nozzle. At the same time, pressured gas fills the center of the extruded hollow liquid pipe that breaks into hollow spheres. The environment outside the nozzles contains gas at a high pressure such as 100 atmospheres. Gas is supplied to the gas nozzle at a slightly higher pressure such as 101 atmospheres. The pressure applied to the molten material is at a still higher pressure such as 110 atmospheres.

  9. Coulomb energy of uniformly charged spheroidal shell systems.

    PubMed

    Jadhao, Vikram; Yao, Zhenwei; Thomas, Creighton K; de la Cruz, Monica Olvera

    2015-03-01

    We provide exact expressions for the electrostatic energy of uniformly charged prolate and oblate spheroidal shells. We find that uniformly charged prolate spheroids of eccentricity greater than 0.9 have lower Coulomb energy than a sphere of the same area. For the volume-constrained case, we find that a sphere has the highest Coulomb energy among all spheroidal shells. Further, we derive the change in the Coulomb energy of a uniformly charged shell due to small, area-conserving perturbations on the spherical shape. Our perturbation calculations show that buckling-type deformations on a sphere can lower the Coulomb energy. Finally, we consider the possibility of counterion condensation on the spheroidal shell surface. We employ a Manning-Oosawa two-state model approximation to evaluate the renormalized charge and analyze the behavior of the equilibrium free energy as a function of the shell's aspect ratio for both area-constrained and volume-constrained cases. Counterion condensation is seen to favor the formation of spheroidal structures over a sphere of equal area for high values of shell volume fractions.

  10. Effects of material composition on the ablation performance of low density elastomeric ablators

    NASA Technical Reports Server (NTRS)

    Tompkins, S. S.; Kabana, W. P.

    1973-01-01

    The ablation performance of materials composed of various concentrations of nylon, hollow silica spheres, hollow phenolic spheres, and four elastomeric resins was determined. Both blunt-body and flat-panel specimens were used, the cold-wall heating-rate ranges being 0.11 to 0.8 MW/sq m, respectively. The corresponding surface pressure ranges for these tests were 0.017 to 0.037 atmosphere and 0.004 to 0.005 atmosphere. Some of the results show that (1) the addition of nylon significantly improved the ablation performance, but the nylon was not compatible with one resin system; (2) panel and blunt-body specimen data do not show the same effect of phenolic sphere content on ablation effectiveness; and (3) there appears to be an optimum concentration of hollow silica spheres for good ablation performance. The composition of an efficient, nonproprietary ablator for lifting body application is identified and the ablation performance of this ablator is compared with the performance of three commercially available materials.

  11. Green Color Purification in Tb(3+) Ions through Silica Inverse Opal Heterostructure.

    PubMed

    Shrivastava, Vishnu Prasad; Sivakumar, Sri; Kumar, Jitendra

    2015-06-10

    The ordered SiO2:Tb(3+) inverse opal heterostructure films are fabricated through polystyrene spheres hetero-opal template using the convective self-assembly method to examine their potential for color purification. Their optical properties and photoluminescence have been investigated and compared with individual single inverse opals and reference (SiO2:Tb(3+) powder). The heterostructures are shown to possess two broad photonic stop bands separated by an effective pass band, causing suppression of blue, orange, and red emission bands corresponding to (5)D4 → (7)F(j); j = 6, 4, 3 transitions, respectively and an enhancement of green emission (i.e., (5)D4 → (7)F5). Although the suppression of various emission occurs because of its overlap with the photonic band gaps (PSBs), the enhancement of green radiation is observed because of its location matching with the pass band region. The Commission International de l'Eclairage (CIE) chromaticity coordinates of the emission spectrum of the heterostructure based on polystyrene sphere of 390 and 500 nm diameter are x = 0.2936, y = 0.6512 and lie closest to those of standard green color (wavelength 545 nm). In addition, a significant increase observed in luminescence lifetime for (5)D4 level of terbium in inverse opal heterostructures vis-à-vis reference (SiO2:Tb(3+) powder) is attributed to the change in the effective refractive index.

  12. Combustion of a Polymer (PMMA) Sphere in Microgravity

    NASA Technical Reports Server (NTRS)

    Yang, Jiann C.; Hamins, Anthony; Donnelly, Michelle K.

    1999-01-01

    A series of low gravity, aircraft-based, experiments was conducted to investigate the combustion of supported thermoplastic polymer spheres under varying ambient conditions. The three types of thermoplastic investigated were polymethylmethacrylate (PMMA), polypropylene (PP). and polystyrene (PS). Spheres with diameters ranging from 2 mm to 6.35 mm were tested. The total initial pressure varied from 0.05 MPa to 0. 15 MPa whereas the ambient oxygen concentration varied from 19 % to 30 % (by volume). The ignition system consisted of a pair of retractable energized coils. Two CCD cameras recorded the burning histories of the spheres. The video sequences revealed a number of dynamic events including bubbling and sputtering, as well as soot shell formation and break-up during combustion of the spheres at reduced gravity. The ejection of combusting material from the burning spheres represents a fire hazard that must be considered at reduced gravity. The ejection process was found to be sensitive to polymer type. All average burning rates were measured to increase with initial sphere diameter and oxygen concentration, whereas the initial pressure had little effect. The three thermoplastic types exhibited different burning characteristics. For the same initial conditions, the burning rate of PP was slower than PMMA, whereas the burning rate of PS was comparable to PMMA. The transient diameter of the burning thermoplastic exhibited two distinct periods: an initial period (enduring approximately half of the total burn duration) when the diameter remained approximately constant, and a final period when the square of the diameter linearly decreased with time. A simple homogeneous two-phase model was developed to understand the changing diameter of the burning sphere. Its value is based on a competition between diameter reduction due to mass loss from burning and sputtering, and diameter expansion due to the processes of swelling (density decrease with heating) and bubble growth. The model relies on empirical parameters for input, such as the burning rate and the duration of the initial and final burning periods.

  13. Bond-orientational analysis of hard-disk and hard-sphere structures.

    PubMed

    Senthil Kumar, V; Kumaran, V

    2006-05-28

    We report the bond-orientational analysis results for the thermodynamic, random, and homogeneously sheared inelastic structures of hard-disks and hard-spheres. The thermodynamic structures show a sharp rise in the order across the freezing transition. The random structures show the absence of crystallization. The homogeneously sheared structures get ordered at a packing fraction higher than the thermodynamic freezing packing fraction, due to the suppression of crystal nucleation. On shear ordering, strings of close-packed hard-disks in two dimensions and close-packed layers of hard-spheres in three dimensions, oriented along the velocity direction, slide past each other. Such a flow creates a considerable amount of fourfold order in two dimensions and body-centered-tetragonal (bct) structure in three dimensions. These transitions are the flow analogs of the martensitic transformations occurring in metals due to the stresses induced by a rapid quench. In hard-disk structures, using the bond-orientational analysis we show the presence of fourfold order. In sheared inelastic hard-sphere structures, even though the global bond-orientational analysis shows that the system is highly ordered, a third-order rotational invariant analysis shows that only about 40% of the spheres have face-centered-cubic (fcc) order, even in the dense and near-elastic limits, clearly indicating the coexistence of multiple crystalline orders. When layers of close-packed spheres slide past each other, in addition to the bct structure, the hexagonal-close-packed (hcp) structure is formed due to the random stacking faults. Using the Honeycutt-Andersen pair analysis and an analysis based on the 14-faceted polyhedra having six quadrilateral and eight hexagonal faces, we show the presence of bct and hcp signatures in shear ordered inelastic hard-spheres. Thus, our analysis shows that the dense sheared inelastic hard-spheres have a mixture of fcc, bct, and hcp structures.

  14. Biological interactions in vitro of zinc oxide nanoparticles of different characteristics

    NASA Astrophysics Data System (ADS)

    Aula, Sangeetha; Lakkireddy, Samyuktha; AVN, Swamy; Kapley, Atya; Jamil, Kaiser; Rao Tata, Narasinga; Hembram, Kaliyan

    2014-09-01

    Zinc oxide nanoparticles (ZnO NPs) have recently received growing attention for various biomedical applications, including use as therapeutic or carrier for drug delivery and/or imaging. For the above applications, the NPs necessitate administration into the body leading to their systemic exposure. To better anticipate the safety, make risk assessment, and be able to interpret the future preclinical and clinical safety data, it is important to systematically understand the biological interaction of the NPs, the consequences of such interaction, and the mechanisms associated with the toxicity induction, with the important components with which the NPs are expected to be in contact after systemic exposure. In this context, we report here a detailed study on the biological interactions in vitro of the ZnO NPs with healthy human primary lymphocytes as these are the important immune components and the first systemic immune contact, and with the whole human blood. Additionally, the influence, if any, of the NPs shape (spheres and rods) on the biological interaction has been evaluated. The ZnO NPs caused toxicity (30% at 12.5 μg ml-1 spheres and 10.5 μg ml-1 rods; 50% at 22 μg ml-1 spheres and 19.5 μg ml-1 rods) to the lymphocytes at molecular and genetic level in a dose-dependent and shape-dependent manner, while the interaction consequences with the blood and blood components such as RBC, platelets was only dose-dependent and not shape-dependent. This is evident from the decreased RBC count due to increased %Hemolysis (5.3% in both the spheres- and rods-treated blood) and decreased platelet count due to increased %platelet aggregation (28% in spheres-treated and 33% in rods-treated platelet-rich plasma). Such in-depth understanding of the biological interaction of the NPs, the consequences, and the associated mechanisms in vitro could be expected to allow anticipating the NP safety for risk assessment and for interpretation of the preclinical and clinical safety data when available.

  15. A volumetric conformal mapping approach for clustering white matter fibers in the brain

    PubMed Central

    Gupta, Vikash; Prasad, Gautam; Thompson, Paul

    2017-01-01

    The human brain may be considered as a genus-0 shape, topologically equivalent to a sphere. Various methods have been used in the past to transform the brain surface to that of a sphere using harmonic energy minimization methods used for cortical surface matching. However, very few methods have studied volumetric parameterization of the brain using a spherical embedding. Volumetric parameterization is typically used for complicated geometric problems like shape matching, morphing and isogeometric analysis. Using conformal mapping techniques, we can establish a bijective mapping between the brain and the topologically equivalent sphere. Our hypothesis is that shape analysis problems are simplified when the shape is defined in an intrinsic coordinate system. Our goal is to establish such a coordinate system for the brain. The efficacy of the method is demonstrated with a white matter clustering problem. Initial results show promise for future investigation in these parameterization technique and its application to other problems related to computational anatomy like registration and segmentation. PMID:29177252

  16. Molecular dynamics simulation of a needle-sphere binary mixture

    NASA Astrophysics Data System (ADS)

    Raghavan, Karthik

    This paper investigates the dynamic behaviour of a hard needle-sphere binary system using a novel numerical technique called the Newton homotopy continuation (NHC) method. This mixture is representative of a polymer melt where both long chain molecules and monomers coexist. Since the intermolecular forces are generated from hard body interactions, the consequence of missed collisions or incorrect collision sequences have a significant bearing on the dynamic properties of the fluid. To overcome this problem, in earlier work NHC was chosen over traditional Newton-Raphson methods to solve the hard body dynamics of a needle fluid in random media composed of overlapping spheres. Furthermore, the simplicity of interactions and dynamics allows us to focus our research directly on the effects of particle shape and density on the transport behaviour of the mixture. These studies are also compared with earlier works that examined molecular chains in porous media primarily to understand the differences in molecular transport in the bulk versus porous systems.

  17. Assembly of hard spheres in a cylinder: a computational and experimental study.

    PubMed

    Fu, Lin; Bian, Ce; Shields, C Wyatt; Cruz, Daniela F; López, Gabriel P; Charbonneau, Patrick

    2017-05-14

    Hard spheres are an important benchmark of our understanding of natural and synthetic systems. In this work, colloidal experiments and Monte Carlo simulations examine the equilibrium and out-of-equilibrium assembly of hard spheres of diameter σ within cylinders of diameter σ≤D≤ 2.82σ. Although phase transitions formally do not exist in such systems, marked structural crossovers can nonetheless be observed. Over this range of D, we find in simulations that structural crossovers echo the structural changes in the sequence of densest packings. We also observe that the out-of-equilibrium self-assembly depends on the compression rate. Slow compression approximates equilibrium results, while fast compression can skip intermediate structures. Crossovers for which no continuous line-slip exists are found to be dynamically unfavorable, which is the main source of this difference. Results from colloidal sedimentation experiments at low diffusion rate are found to be consistent with the results of fast compressions, as long as appropriate boundary conditions are used.

  18. Re-accumulation Scenarios Governing Final Global Shapes of Rubble-Pile Asteroids

    NASA Astrophysics Data System (ADS)

    Hestroffer, Daniel; Tanga, P.; Comito, C.; Paolicchi, P.; Walsh, K.; Richardson, D. C.; Cellino, A.

    2009-05-01

    Asteroids, since the formation of the solar system, are known to have experienced catastrophic collisions, which---depending on the impact energy---can produce a major disruption of the parent body and possibly give birth to asteroid families or binaries [1]. We present a general study of the final shape and dynamical state of asteroids produced by the re-accumulation process following a catastrophic disruption. Starting from a cloud of massive particles (mono-disperse spheres) with given density and velocity distributions, we analyse the final shape, spin state, and angular momentum of the system from numerical integration of a N-body gravitational system (code pkdgrav [2]). The re-accumulation process itself is relatively fast, with a dynamical time corresponding to the spin-period of the final body (several hours). The final global shapes---which are described as tri-axial ellipsoids---exhibit slopes consistent with a degree of shear stress sustained by interlocking particles. We point out a few results: -the final shapes are close to those of hydrostatic equilibrium for incompressible fluids, preferably Maclaurin spheroid rather than Jacobi ellipsoids -for bodies closest to the sequence of hydrostatic equilibrium, there is a direct relation between spin, density and outer shape, suggesting that the outer surface is nearly equipotential -the evolution of the shape during the process follows a track along a gradient of potential energy, without necessarily reaching its minimum -the loose random packing of the particles implies low friction angle and hence fluid-like behaviour, which extends the results of [3]. Future steps of our analysis will include feature refinements of the model initial conditions and re-accumulation process, including impact shakings, realistic velocity distributions, and non equal-sized elementary spheres. References [1] Michel P. et al. 2001. Science 294, 1696 [2] Leinhardt Z.M. et al. 2000. Icarus 146, 133 [3] Richardson D.C. et al. 2005. Icarus 173, 349

  19. Many-body dynamics of chemically propelled nanomotors

    NASA Astrophysics Data System (ADS)

    Colberg, Peter H.; Kapral, Raymond

    2017-08-01

    The collective behavior of chemically propelled sphere-dimer motors made from linked catalytic and noncatalytic spheres in a quasi-two-dimensional confined geometry is studied using a coarse-grained microscopic dynamical model. Chemical reactions at the catalytic spheres that convert fuel to product generate forces that couple to solvent degrees of freedom as a consequence of momentum conservation in the microscopic dynamics. The collective behavior of the many-body system is influenced by direct intermolecular interactions among the motors, chemotactic effects due to chemical gradients, hydrodynamic coupling, and thermal noise. Segregation into high and low density phases and globally homogeneous states with strong fluctuations are investigated as functions of the motor characteristics. Factors contributing to this behavior are discussed in the context of active Brownian models.

  20. Communication: Virial coefficients and demixing in highly asymmetric binary additive hard-sphere mixtures.

    PubMed

    López de Haro, Mariano; Tejero, Carlos F; Santos, Andrés

    2013-04-28

    The problem of demixing in a binary fluid mixture of highly asymmetric additive hard spheres is revisited. A comparison is presented between the results derived previously using truncated virial expansions for three finite size ratios with those that one obtains with the same approach in the extreme case in which one of the components consists of point particles. Since this latter system is known not to exhibit fluid-fluid segregation, the similarity observed for the behavior of the critical constants arising in the truncated series in all instances, while not being conclusive, may cast serious doubts as to the actual existence of a demixing fluid-fluid transition in disparate-sized binary additive hard-sphere mixtures.

  1. Hard Spheres on the Primitive Surface

    NASA Astrophysics Data System (ADS)

    Dotera, Tomonari; Takahashi, Yusuke

    2015-03-01

    Recently hierarchical structures associated with the gyroid in several soft-matter systems have been reported. One of fundamental questions is regular arrangement or tiling on minimal surfaces. We have found certain numbers of hard spheres per unit cell on the gyroid surface are entropically self-organized. Here, new results for the primitive surface are presented. 56/64/72 per unit cell on the primitive minimal surface are entropically self-organized. Numerical evidences for the fluid-solid transition as a function of hard sphere radius are obtained in terms of the acceptance ratio of Monte Carlo moves and order parameters. These arrangements, which are the extensions of the hexagonal arrangement on a flat surface, can be viewed as hyperbolic tiling on the Poincaré disk with a negative Gaussian curvature.

  2. Locating responsibility: the Sphere Humanitarian Charter and its rationale.

    PubMed

    Darcy, James

    2004-06-01

    Criticised by some as a technical initiative that neglects core principles, Sphere was seen by its originators precisely as an articulation of principle. The Humanitarian Charter was the main vehicle through which this was expressed, but its relationship to the Minimum Standards has remained a matter of uncertainty. Specifically, it was unclear in the original (1999) edition of Sphere how the concept of rights informed the Minimum Standards. The revised (2004) edition goes some way to clarifying this in the way the standards are framed, yet the link between the standards and the charter remains unclear. The concern with the quality and accountability of humanitarian assistance, which motivated the attempt to establish system-wide standards through the Sphere Project, was accompanied by a desire to establish such actions in a wider framework of legal and political responsibility. In part, this reflects the conditional nature of the undertaking that agencies make when they adopt Sphere. This aspect of the charter has been neglected, but it is fundamental to an understanding of the standards and their application. This paper considers the rationale of the Sphere Humanitarian Charter and the conceptual model that underpins it. It discusses the relationship between the charter and the Minimum Standards, and the sense in which the latter are properly called "rights-based" (explored further in a related paper herein by Young and Taylor). The author was closely involved in the conception and drafting of the charter, and this paper attempts to convey some of the thinking that lay behind it.

  3. Parental share in public and domestic spheres: a population study on gender equality, death, and sickness

    PubMed Central

    Månsdotter, Anna; Lindholm, Lars; Lundberg, Michael; Winkvist, Anna; Öhman, Ann

    2006-01-01

    Study objective Examine the relation between aspects of gender equality and population health based on the premise that sex differences in health are mainly caused by the gender system. Setting/participants All Swedish couples (98 240 people) who had their first child together in 1978. Design The exposure of gender equality is shown by the parents' division of income and occupational position (public sphere), and parental leave and temporary child care (domestic sphere). People were classified by these indicators during 1978–1980 into different categories; those on an equal footing with their partner and those who were traditionally or untraditionally unequal. Health is measured by the outcomes of death during 1981–2001 and sickness absence during 1986–2000. Data are obtained by linking individual information from various national sources. The statistical method used is multiple logistic regressions with odds ratios as estimates of relative risks. Main results From the public sphere is shown that traditionally unequal women have decreased health risks compared with equal women, while traditionally unequal men tend to have increased health risks compared with equal men. From the domestic sphere is indicated that both women and men run higher risks of death and sickness when being traditionally unequal compared with equal. Conclusions Understanding the relation between gender equality and health, which was found to depend on sex, life sphere, and inequality type, seems to require a combination of the hypotheses of convergence, stress and expansion. PMID:16790834

  4. Nuclear spin relaxation in ligands outside of the first coordination sphere in a gadolinium (III) complex: Effects of intermolecular forces

    NASA Astrophysics Data System (ADS)

    Kruk, Danuta; Kowalewski, Jozef

    2002-07-01

    This article describes paramagnetic relaxation enhancement (PRE) in systems with high electron spin, S, where there is molecular interaction between a paramagnetic ion and a ligand outside of the first coordination sphere. The new feature of our treatment is an improved handling of the electron-spin relaxation, making use of the Redfield theory. Following a common approach, a well-defined second coordination sphere is assumed, and the PRE contribution from these more distant and shorter-lived ligands is treated in a way similar to that used for the first coordination sphere. This model is called "ordered second sphere," OSS. In addition, we develop here a formalism similar to that of Hwang and Freed [J. Chem. Phys. 63, 4017 (1975)], but accounting for the electron-spin relaxation effects. We denote this formalism "diffuse second sphere," DSS. The description of the dynamics of the intermolecular dipole-dipole interaction is based on the Smoluchowski equation, with a potential of mean force related to the radial distribution function. We have used a finite-difference method to calculate numerically a correlation function for translational motion, taking into account the intermolecular forces leading to an arbitrary radial distribution of the ligand protons. The OSS and DSS models, including the Redfield description of the electron-spin relaxation, were used to interpret the PRE in an aqueous solution of a slowly rotating gadolinium (III) complex (S=7/2) bound to a protein.

  5. OPTICAL SPECTRA OF CANDIDATE SOUTHERN HEMISPHERE INTERNATIONAL CELESTIAL REFERENCE FRAME (ICRF) RADIO SOURCES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Titov, O.; Jauncey, D. L.; Johnston, H. M.

    2011-11-15

    We present the results of spectroscopic observations of the optical counterparts of 47 southern radio sources from the candidate International Celestial Reference Catalogue as part of a very long baseline interferometry (VLBI) program to strengthen the celestial reference frame, especially in the south. We made the observations with the 3.58 m European Southern Observatory New Technology Telescope. We obtained redshifts for 30 quasars and one radio galaxy, with a further seven objects being probable BL Lac objects with featureless spectra. Of the remainder, four were clear misidentifications with Galactic stars and five had low signal-to-noise spectra and could not bemore » classified. These results, in combination with new VLBI data of the radio sources with redshifts more than 2, add significantly to the existing data needed to refine the distribution of source proper motions over the celestial sphere.« less

  6. Three-Dimensional Self-Assembled Photonic Crystal Waveguide

    NASA Astrophysics Data System (ADS)

    Baek, Kang-Hyun

    Photonic crystals (PCs), two- or three-dimensionally periodic, artificial, and dielectric structures, have a specific forbidden band for electromagnetic waves, referred to as photonic bandgap (PBG). The PBG is analogous to the electronic bandgap in natural crystal structures with periodic atomic arrangement. A well-defined and embedded planar, line, or point defect within the PCs causes a break in its structural periodicity, and introduces a state in the PBG for light localization. It offers various applications in integrated optics and photonics including optical filters, sharp bending light guides and very low threshold lasers. Using nanofabrication processes, PCs of the 2-D slab-type and 3-D layer-by-layer structures have been investigated widely. Alternatively, simple and low-cost self-assembled PCs with full 3-D PBG, inverse opals, have been suggested. A template with face centered cubic closed packed structure, opal, may initially be built by self-assembly of colloidal spheres, and is selectively removed after infiltrating high refractive index materials into the interstitials of spheres. In this dissertation, the optical waveguides utilizing the 3-D self-assembled PCs are discussed. The waveguides were fabricated by microfabrication technology. For high-quality colloidal silica spheres and PCs, reliable synthesis, self-assembly, and characterization techniques were developed. Its theoretical and experimental demonstrations are provided and correlated. They suggest that the self-assembled PCs with PBG are feasible for the applications in integrated optics and photonics.

  7. Selective encapsulation by Janus particles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Wei, E-mail: wel208@mrl.ucsb.edu; Ruth, Donovan; Gunton, James D.

    2015-06-28

    We employ Monte Carlo simulation to examine encapsulation in a system comprising Janus oblate spheroids and isotropic spheres. More specifically, the impact of variations in temperature, particle size, inter-particle interaction range, and strength is examined for a system in which the spheroids act as the encapsulating agents and the spheres as the encapsulated guests. In this picture, particle interactions are described by a quasi-square-well patch model. This study highlights the environmental adaptation and selectivity of the encapsulation system to changes in temperature and guest particle size, respectively. Moreover, we identify an important range in parameter space where encapsulation is favored,more » as summarized by an encapsulation map. Finally, we discuss the generalization of our results to systems having a wide range of particle geometries.« less

  8. Identification Of Cells With A Compact Microscope Imaging System With Intelligent Controls

    NASA Technical Reports Server (NTRS)

    McDowell, Mark (Inventor)

    2006-01-01

    A Microscope Imaging System (CMIS) with intelligent controls is disclosed that provides techniques for scanning, identifying, detecting and tracking mic?oscopic changes in selected characteristics or features of various surfaces including, but not limited to, cells, spheres, and manufactured products subject to difficult-to-see imperfections. The practice of the present invention provides applications that include colloidal hard spheres experiments, biological cell detection for patch clamping, cell movement and tracking, as well as defect identification in products, such as semiconductor devices, where surface damage can be significant, but difficult to detect. The CMIS system is a machine vision system, which combines intelligent image processing with remote control capabilities and provides the ability to autofocus on a microscope sample, automatically scan an image, and perform machine vision analysis on multiple samples simultaneously.

  9. Tracking of Cells with a Compact Microscope Imaging System with Intelligent Controls

    NASA Technical Reports Server (NTRS)

    McDowell, Mark (Inventor)

    2007-01-01

    A Microscope Imaging System (CMIS) with intelligent controls is disclosed that provides techniques for scanning, identifying, detecting and tracking microscopic changes in selected characteristics or features of various surfaces including, but not limited to, cells, spheres, and manufactured products subject to difficult-to-see imperfections. The practice of the present invention provides applications that include colloidal hard spheres experiments, biological cell detection for patch clamping, cell movement and tracking, as well as defect identification in products, such as semiconductor devices, where surface damage can be significant, but difficult to detect. The CMIS system is a machine vision system, which combines intelligent image processing with remote control capabilities and provides the ability to autofocus on a microscope sample, automatically scan an image, and perform machine vision analysis on multiple samples simultaneously

  10. Tracking of cells with a compact microscope imaging system with intelligent controls

    NASA Technical Reports Server (NTRS)

    McDowell, Mark (Inventor)

    2007-01-01

    A Microscope Imaging System (CMIS) with intelligent controls is disclosed that provides techniques for scanning, identifying, detecting and tracking microscopic changes in selected characteristics or features of various surfaces including, but not limited to, cells, spheres, and manufactured products subject to difficult-to-see imperfections. The practice of the present invention provides applications that include colloidal hard spheres experiments, biological cell detection for patch clamping, cell movement and tracking, as well as defect identification in products, such as semiconductor devices, where surface damage can be significant, but difficult to detect. The CMIS system is a machine vision system, which combines intelligent image processing with remote control capabilities and provides the ability to auto-focus on a microscope sample, automatically scan an image, and perform machine vision analysis on multiple samples simultaneously.

  11. Operation of a Cartesian Robotic System in a Compact Microscope with Intelligent Controls

    NASA Technical Reports Server (NTRS)

    McDowell, Mark (Inventor)

    2006-01-01

    A Microscope Imaging System (CMIS) with intelligent controls is disclosed that provides techniques for scanning, identifying, detecting and tracking microscopic changes in selected characteristics or features of various surfaces including, but not limited to, cells, spheres, and manufactured products subject to difficult-to-see imperfections. The practice of the present invention provides applications that include colloidal hard spheres experiments, biological cell detection for patch clamping, cell movement and tracking, as well as defect identification in products, such as semiconductor devices, where surface damage can be significant, but difficult to detect. The CMIS system is a machine vision system, which combines intelligent image processing with remote control capabilities and provides the ability to autofocus on a microscope sample, automatically scan an image, and perform machine vision analysis on multiple samples simultaneously.

  12. The High Energy Astronomy Observatory X-ray Telescope

    NASA Technical Reports Server (NTRS)

    Miller, R.; Austin, G.; Koch, D.; Jagoda, N.; Kirchner, T.; Dias, R.

    1978-01-01

    The High Energy Astronomy Observatory-Mission B (HEAO-B) is a satellite observatory for the purpose of performing a detailed X-ray survey of the celestial sphere. Measurements will be made of stellar radiation in the range 0.2 through 20 keV. The primary viewing requirement is to provide final aspect solution and internal alignment information to correlate an observed X-ray image with the celestial sphere to within one-and-one-half arc seconds. The Observatory consists of the HEAO Spacecraft together with the X-ray Telescope. The Spacecraft provides the required attitude control and determination system, data telemetry system, space solar power system, and interface with the launch vehicle. The X-ray Telescope includes a high resolution mirror assembly, optical bench metering structure, X-ray detectors, detector positioning system, detector electronics and aspect sensing system.

  13. Testing Bonner sphere spectrometers in the JRC-IRMM mono-energetic neutron beams

    NASA Astrophysics Data System (ADS)

    Bedogni, R.; Domingo, C.; Esposito, A.; Chiti, M.; García-Fusté, M. J.; Lovestam, G.

    2010-08-01

    Within the framework of the Euratom Transnational Access programme, a specific sub-programme, called NUDAME (neutron data measurements at IRMM), was dedicated to support neutron measurement experiments at the accelerator-based facilities of the JRC-IRMM Geel, Belgium. In this context, the INFN-LNF and UAB groups undertook two separate experiments at the 7 MV Van de Graaff facility, aimed at testing their Bonner sphere spectrometers (BSS) with mono-energetic neutron beams. Both research groups routinely employ the BSS in neutron spectra measurements for radiation protection dosimetry purposes, where accurate knowledge of the BSS response is a mandatory condition for correct dose evaluations. This paper presents the results obtained by both groups, focusing on: (1) the comparison between the value of neutron fluence provided as reference data and that obtained by applying the FRUIT unfolding code to the measured BSS data and (2) the experimental validation of the response matrices of the BSSs, previously derived with Monte Carlo simulations.

  14. Accuracy of digital models generated by conventional impression/plaster-model methods and intraoral scanning.

    PubMed

    Tomita, Yuki; Uechi, Jun; Konno, Masahiro; Sasamoto, Saera; Iijima, Masahiro; Mizoguchi, Itaru

    2018-04-17

    We compared the accuracy of digital models generated by desktop-scanning of conventional impression/plaster models versus intraoral scanning. Eight ceramic spheres were attached to the buccal molar regions of dental epoxy models, and reference linear-distance measurement were determined using a contact-type coordinate measuring instrument. Alginate (AI group) and silicone (SI group) impressions were taken and converted into cast models using dental stone; the models were scanned using desktop scanner. As an alternative, intraoral scans were taken using an intraoral scanner, and digital models were generated from these scans (IOS group). Twelve linear-distance measurement combinations were calculated between different sphere-centers for all digital models. There were no significant differences among the three groups using total of six linear-distance measurements. When limited to five lineardistance measurement, the IOS group showed significantly higher accuracy compared to the AI and SI groups. Intraoral scans may be more accurate compared to scans of conventional impression/plaster models.

  15. Properties of a soft-core model of methanol: An integral equation theory and computer simulation study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huš, Matej; Urbic, Tomaz, E-mail: tomaz.urbic@fkkt.uni-lj.si; Munaò, Gianmarco

    Thermodynamic and structural properties of a coarse-grained model of methanol are examined by Monte Carlo simulations and reference interaction site model (RISM) integral equation theory. Methanol particles are described as dimers formed from an apolar Lennard-Jones sphere, mimicking the methyl group, and a sphere with a core-softened potential as the hydroxyl group. Different closure approximations of the RISM theory are compared and discussed. The liquid structure of methanol is investigated by calculating site-site radial distribution functions and static structure factors for a wide range of temperatures and densities. Results obtained show a good agreement between RISM and Monte Carlo simulations.more » The phase behavior of methanol is investigated by employing different thermodynamic routes for the calculation of the RISM free energy, drawing gas-liquid coexistence curves that match the simulation data. Preliminary indications for a putative second critical point between two different liquid phases of methanol are also discussed.« less

  16. 3D investigation on polystyrene colloidal crystals by floatage self-assembly with mixed solvent via synchrotron radiation x-ray phase-contrast computed tomography

    NASA Astrophysics Data System (ADS)

    Fu, Yanan; Xie, Honglan; Deng, Biao; Du, Guohao; Xiao, Tiqiao

    2017-06-01

    The floatage self-assembly method was introduced with mixed solvent as the medium of polystyrene sphere suspension to fabricate the colloidal crystal. The three dimensional (3D) void system of the colloidal crystal was noninvasively characterized by synchrotron radiation phase-contrast computed tomography, and the quantitative image analysis was implemented aiming to the polystyrene sphere colloidal crystal. Comparing with gravity sedimentation method, the three samples fabricated from floatage self-assembly with mixed solvents have the lowest porosity, and when ethylene glycol and water were mixed with ratio of 1:1, the lowest porosity of 27.49% could be achieved, that has been very close to the minimum porosity of ordered 3D monodisperse sphere array (26%). In single slices, the porosities and fractal dimension for the voids were calculated. The results showed that two factors would significantly influence the porosity of the whole colloidal crystal: the first deposited sphere layer's orderliness and the sedimentation speed of the spheres. The floatage self-assembly could induce a stable close-packing process, resulted from the powerful nucleation force-lateral capillary force coupled with the mixed solvent to regulate the floating upward speed for purpose of matching the assembly rate.

  17. When the private sphere goes public: exploring the issues facing family caregiver organizations in the development of long-term care policies.

    PubMed

    Rozario, Philip A; Palley, Elizabeth

    2008-01-01

    Though family caregiving forms the backbone of the long-term care system in the United States, long-term care policies have traditionally focused on paid services that frail older people and people with disabilities utilize for their day-to-day functioning. Part of the exclusion of family caregiving from the long-term care discourse stems from the traditional separation of the private sphere, where family caregiving occurs, from the public sphere of policy making. However, the passage of the Family and Medical Leave Act (FMLA), the National Family Caregiver Support Program (NFCSP) and Medicaid waiver legislation may reflect recent changes in the government's position on their role in addressing issues related to the "private spheres." In this article, we explore the nature of family caregiving in the United States, the divide between the public and private spheres and provide an overview of family caregiving-related policies and programs in the U.S. In our review, we examine the provisions in the FMLA, NFCSP, and Medicaid waiver legislation that support family caregiving efforts. We also examine the roles of family caregiver organizations in making family caregiving an important element of long-term care policy and influencing policy-making.

  18. Fabrication of ф 160 mm convex hyperbolic mirror for remote sensing instrument

    NASA Astrophysics Data System (ADS)

    Kuo, Ching-Hsiang; Yu, Zong-Ru; Ho, Cheng-Fang; Hsu, Wei-Yao; Chen, Fong-Zhi

    2012-10-01

    In this study, efficient polishing processes with inspection procedures for a large convex hyperbolic mirror of Cassegrain optical system are presented. The polishing process combines the techniques of conventional lapping and CNC polishing. We apply the conventional spherical lapping process to quickly remove the sub-surface damage (SSD) layer caused by grinding process and to get the accurate radius of best-fit sphere (BFS) of aspheric surface with fine surface texture simultaneously. Thus the removed material for aspherization process can be minimized and the polishing time for SSD removal can also be reduced substantially. The inspection procedure was carried out by using phase shift interferometer with CGH and stitching technique. To acquire the real surface form error of each sub aperture, the wavefront errors of the reference flat and CGH flat due to gravity effect of the vertical setup are calibrated in advance. Subsequently, we stitch 10 calibrated sub-aperture surface form errors to establish the whole irregularity of the mirror in 160 mm diameter for correction polishing. The final result of the In this study, efficient polishing processes with inspection procedures for a large convex hyperbolic mirror of Cassegrain optical system are presented. The polishing process combines the techniques of conventional lapping and CNC polishing. We apply the conventional spherical lapping process to quickly remove the sub-surface damage (SSD) layer caused by grinding process and to get the accurate radius of best-fit sphere (BFS) of aspheric surface with fine surface texture simultaneously. Thus the removed material for aspherization process can be minimized and the polishing time for SSD removal can also be reduced substantially. The inspection procedure was carried out by using phase shift interferometer with CGH and stitching technique. To acquire the real surface form error of each sub aperture, the wavefront errors of the reference flat and CGH flat due to gravity effect of the vertical setup are calibrated in advance. Subsequently, we stitch 10 calibrated sub-aperture surface form errors to establish the whole irregularity of the mirror in 160 mm diameter for correction polishing. The final result of the Fabrication of ф160 mm Convex Hyperbolic Mirror for Remote Sensing Instrument160 mm convex hyperbolic mirror is 0.15 μm PV and 17.9 nm RMS.160 mm convex hyperbolic mirror is 0.15 μm PV and 17.9 nm RMS.

  19. Interactions of solvent with the heme region of methemoglobin and fluoro-methemoglobin.

    PubMed

    Koenig, S H; Brown, R D; Lindstrom, T R

    1981-06-01

    It is now more than 20 years since Davidson and collaborators (1957, Biochim. Biophys, Acta. 26:370-373; J. Mol. Biol. 1:190-191) applied the theoretical ideas of Bloembergen et al. (1948. Phys. Rev. 73:679-712) on outer sphere magnetic relaxation of solvent protons to studies of solutions of methemoglobin. From then on, there has been debate regarding the relative contributions to paramagnetic solvent proton relaxation by inner sphere (ligand-exchange) effects and by outer sphere (diffusional) effects in methemoglobin solutions. Gupta and Mildvan (1975. J. Biol. Chem 250:146-253) extended the early measurements, attributed the relatively small paramagnetic effects to exchange with solvent of the water ligand of the heme-Fe3+ ion, and interpreted their data to indicate cooperativity and an alkaline Bohr effect in the presence of inositol hexaphosphate. They neglected the earlier discussions entirely, and made no reference to outer sphere effects. We have measured the relaxation rate of solvent protons as a function of magnetic field for solutions of methemoglobin, under a variety of conditions of pH and temperature, and have given careful consideration to the relatively large diamagnetic corrections that are necessary by making analogous measurements on oxyhemoglobin, carbonmonoxyhemoglobin, and cyano- and azide-methemoglobin. (The latter two, because of their short electronic relaxation times, behave as though diamagnetic). We show that the paramagnetic contribution to solvent relaxation can be dominated by outer sphere effects, a result implying that many conclusions, including those of Gupta and Mildvan, require reexamination. Finally, we present data for fluoro-methemoglobin, which relaxes solvent protons an order of magnitude better than does methemoglobin. Here one has a startling breakdown of the dogma that has been the basis for interpreting many ligand-replacement studies; in contrast to the prevailing view that replacement of a water ligand of a protein-bound paramagnetic ion by another ligand should decrease relaxation rates, replacement of H2O by F- increases the relaxation rate drastically. The data can all be reconciled, however, with what is anticipated from knowledge of ligand interactions in the heme region.

  20. Mapping coexistence lines via free-energy extrapolation: application to order-disorder phase transitions of hard-core mixtures.

    PubMed

    Escobedo, Fernando A

    2014-03-07

    In this work, a variant of the Gibbs-Duhem integration (GDI) method is proposed to trace phase coexistence lines that combines some of the advantages of the original GDI methods such as robustness in handling large system sizes, with the ability of histogram-based methods (but without using histograms) to estimate free-energies and hence avoid the need of on-the-fly corrector schemes. This is done by fitting to an appropriate polynomial function not the coexistence curve itself (as in GDI schemes) but the underlying free-energy function of each phase. The availability of a free-energy model allows the post-processing of the simulated data to obtain improved estimates of the coexistence line. The proposed method is used to elucidate the phase behavior for two non-trivial hard-core mixtures: a binary blend of spheres and cubes and a system of size-polydisperse cubes. The relative size of the spheres and cubes in the first mixture is chosen such that the resulting eutectic pressure-composition phase diagram is nearly symmetric in that the maximum solubility of cubes in the sphere-rich solid (∼20%) is comparable to the maximum solubility of spheres in the cube-rich solid. In the polydisperse cube system, the solid-liquid coexistence line is mapped out for an imposed Gaussian activity distribution, which produces near-Gaussian particle-size distributions in each phase. A terminal polydispersity of 11.3% is found, beyond which the cubic solid phase would not be stable, and near which significant size fractionation between the solid and isotropic phases is predicted.

  1. Numerical simulation of a sphere moving down an incline with identical spheres placed equally apart

    USGS Publications Warehouse

    Ling, Chi-Hai; Jan, Chyan-Deng; Chen, Cheng-lung; Shen, Hsieh Wen

    1992-01-01

    This paper describes a numerical study of an elastic sphere moving down an incline with a string of identical spheres placed equally apart. Two momentum equations and a moment equation formulated for the moving sphere are solved numerically for the instantaneous velocity of the moving sphere on an incline with different angles of inclination. Input parameters for numerical simulation include the properties of the sphere (the radius, density, Poison's ratio, and Young's Modulus of elasticity), the coefficient of friction between the spheres, and a damping coefficient of the spheres during collision.

  2. Electrostatic demonstration of free-fall weightlessness

    NASA Astrophysics Data System (ADS)

    Balukovic, Jasmina; Slisko, Josip; Corona Cruz, Adrian

    2015-05-01

    The phenomena of free-fall weightlessness have been demonstrated to students for many years in a number of different ways. The essential basis of all these demonstrations is the fact that in free-falling, gravitationally accelerated systems, the weight force and weight-related forces (for example, friction and hydrostatic forces) disappear. In this article, an original electrostatic demonstration of weightlessness is presented. A charged balloon fixed at the opening of a plastic container cannot lift a light styrofoam sphere sitting on the bottom when the container is at rest. However, while the system is in free-fall, the sphere becomes weightless and the charged balloon is able to lift it electrostatically.

  3. Application of semiclassical and geometrical optics theories to resonant modes of a coated sphere.

    PubMed

    Bambino, Túlio M; Breitschaft, Ana Maria S; Barbosa, Valmar C; Guimarães, Luiz G

    2003-03-01

    This work deals with some aspects of the resonant scattering of electromagnetic waves by a metallic sphere covered by a dielectric layer, in the weak-absorption approximation. We carry out a geometrical optics treatment of the scattering and develop semiclassical formulas to determine the positions and widths of the system resonances. In addition, we show that the mean lifetime of broad resonances is strongly dependent on the polarization of the incident light.

  4. Design, Packaging and Reliability of MEMS S&A Components and Systems

    DTIC Science & Technology

    2006-12-26

    different parameters on stiction likelihood has been studied. The parameters are relative humidity, contact angles, surface roughness, Hamaker constant...cutoff distance of the attractive Van der Waals interaction d, =.2 nm Ah. is the Hamaker media of the materials of the sphere and the half space...interaction in air. Ah.. is the Hamaker media of the materials of the sphere and the half space interaction in water. Hamaker constant can be found using

  5. Enhanced removal of toxic Cr(VI) in tannery wastewater by photoelectrocatalysis with synthetic TiO2 hollow spheres

    NASA Astrophysics Data System (ADS)

    Zhao, Yang; Chang, Wenkai; Huang, Zhiding; Feng, Xugen; Ma, Lin; Qi, Xiaoxia; Li, Zenghe

    2017-05-01

    Owing to the acute toxicity and mobility, the Cr(VI) in tannery wastewater is a huge threat to biological and environmental systems. Herein, an effective photoelectrocatalytic reduction of Cr(VI) was carried out by applying electric field to photocatalysis of as-prepared TiO2 spheres. The synthesis of spherical TiO2 catalytic materials with hollow structure and high surface areas was based on a self-assembly process induced by a mixture of organic acetic acid and ethanol. The possible formation mechanism of TiO2 spheres was proposed and verified by acid concentration-dependent and temperature-dependent experiments. It was found that the reaction rate constant of photoelectrocatalytic reduction of Cr(VI) exhibited an almost 3 fold improvement (0.0362 min-1) as compared to that of photocatalysis (0.0126 min-1). As a result, the mechanism of photoelectrocatalytic reduction of Cr(VI) was described according to the simultaneous determination of Cr(VI), Cr(III) and total Cr in the system. In addition, the effect of pH value and voltage of potential were also discussed. Moreover, this photoelectrocatalysis with TiO2 hollow spheres exhibited excellent activity for reduction of Cr(VI) in actual tannery wastewater produced from three different tanning procedures. These attributes suggest that this photoelectrocatalysis has strong potential applications in the treatment of tannery pollutants.

  6. Structure of finite sphere packings via exact enumeration: Implications for colloidal crystal nucleation

    NASA Astrophysics Data System (ADS)

    Hoy, Robert S.; Harwayne-Gidansky, Jared; O'Hern, Corey S.

    2012-05-01

    We analyze the geometric structure and mechanical stability of a complete set of isostatic and hyperstatic sphere packings obtained via exact enumeration. The number of nonisomorphic isostatic packings grows exponentially with the number of spheres N, and their diversity of structure and symmetry increases with increasing N and decreases with increasing hyperstaticity H≡Nc-NISO, where Nc is the number of pair contacts and NISO=3N-6. Maximally contacting packings are in general neither the densest nor the most symmetric. Analyses of local structure show that the fraction f of nuclei with order compatible with the bulk (rhcp) crystal decreases sharply with increasing N due to a high propensity for stacking faults, five- and near-fivefold symmetric structures, and other motifs that preclude rhcp order. While f increases with increasing H, a significant fraction of hyperstatic nuclei for N as small as 11 retain non-rhcp structure. Classical theories of nucleation that consider only spherical nuclei, or only nuclei with the same ordering as the bulk crystal, cannot capture such effects. Our results provide an explanation for the failure of classical nucleation theory for hard-sphere systems of N≲10 particles; we argue that in this size regime, it is essential to consider nuclei of unconstrained geometry. Our results are also applicable to understanding kinetic arrest and jamming in systems that interact via hard-core-like repulsive and short-ranged attractive interactions.

  7. Advancement of High Resolution Radar Polarimetry in Target Verses Clutter Detection, Discrimination, Classification: A. Basic Theory and Modeling of Polarimetric Clutter Phenomenology.

    DTIC Science & Technology

    1988-07-15

    the interim period, polarimetLic measurement data collected at other DOD/NATO/Industrial R/D/M facilities will be used. These basic studies will be...the polarization sphere and its spread can he related either to the coherency factor or the depolarization factor plus descriptive parameters of the...careful study of the concluding sections outlining the overall scenario of solved and unsolved problems. Here, we also refer to the recent report (Dec

  8. Definition of Physical Height Systems for Telluric Planets and Moons

    NASA Astrophysics Data System (ADS)

    Tenzer, Robert; Foroughi, Ismael; Sjöberg, Lars E.; Bagherbandi, Mohammad; Hirt, Christian; Pitoňák, Martin

    2018-01-01

    In planetary sciences, the geodetic (geometric) heights defined with respect to the reference surface (the sphere or the ellipsoid) or with respect to the center of the planet/moon are typically used for mapping topographic surface, compilation of global topographic models, detailed mapping of potential landing sites, and other space science and engineering purposes. Nevertheless, certain applications, such as studies of gravity-driven mass movements, require the physical heights to be defined with respect to the equipotential surface. Taking the analogy with terrestrial height systems, the realization of height systems for telluric planets and moons could be done by means of defining the orthometric and geoidal heights. In this case, however, the definition of the orthometric heights in principle differs. Whereas the terrestrial geoid is described as an equipotential surface that best approximates the mean sea level, such a definition for planets/moons is irrelevant in the absence of (liquid) global oceans. A more natural choice for planets and moons is to adopt the geoidal equipotential surface that closely approximates the geometric reference surface (the sphere or the ellipsoid). In this study, we address these aspects by proposing a more accurate approach for defining the orthometric heights for telluric planets and moons from available topographic and gravity models, while adopting the average crustal density in the absence of reliable crustal density models. In particular, we discuss a proper treatment of topographic masses in the context of gravimetric geoid determination. In numerical studies, we investigate differences between the geodetic and orthometric heights, represented by the geoidal heights, on Mercury, Venus, Mars, and Moon. Our results reveal that these differences are significant. The geoidal heights on Mercury vary from - 132 to 166 m. On Venus, the geoidal heights are between - 51 and 137 m with maxima on this planet at Atla Regio and Beta Regio. The largest geoid undulations between - 747 and 1685 m were found on Mars, with the extreme positive geoidal heights under Olympus Mons in Tharsis region. Large variations in the geoidal geometry are also confirmed on the Moon, with the geoidal heights ranging from - 298 to 461 m. For comparison, the terrestrial geoid undulations are mostly within ± 100 m. We also demonstrate that a commonly used method for computing the geoidal heights that disregards the differences between the gravity field outside and inside topographic masses yields relatively large errors. According to our estimates, these errors are - 0.3/+ 3.4 m for Mercury, 0.0/+ 13.3 m for Venus, - 1.4/+ 125.6 m for Mars, and - 5.6/+ 45.2 m for the Moon.

  9. Functionalized bioengineered spider silk spheres improve nuclease resistance and activity of oligonucleotide therapeutics providing a strategy for cancer treatment.

    PubMed

    Kozlowska, Anna Karolina; Florczak, Anna; Smialek, Maciej; Dondajewska, Ewelina; Mackiewicz, Andrzej; Kortylewski, Marcin; Dams-Kozlowska, Hanna

    2017-09-01

    Cell-selective delivery and sensitivity to serum nucleases remain major hurdles to the clinical application of RNA-based oligonucleotide therapeutics, such as siRNA. Spider silk shows great potential as a biomaterial due to its biocompatibility and biodegradability. Self-assembling properties of silk proteins allow for processing into several different morphologies such as fibers, scaffolds, films, hydrogels, capsules and spheres. Moreover, bioengineering of spider silk protein sequences can functionalize silk by adding peptide moieties with specific features including binding or cell recognition domains. We demonstrated that modification of silk protein by adding the nucleic acid binding domain enabled the development of a novel oligonucleotide delivery system that can be utilized to improve pharmacokinetics of RNA-based therapeutics, such as CpG-siRNA. The MS2 bioengineered silk was functionalized with poly-lysine domain (KN) to generate hybrid silk MS2KN. CpG-siRNA efficiently bound to MS2KN in contrary to control MS2. Both MS2KN complexes and spheres protected CpG-siRNA from degradation by serum nucleases. CpG-siRNA molecules encapsulated into MS2KN spheres were efficiently internalized and processed by TLR9-positive macrophages. Importantly, CpG-STAT3siRNA loaded in silk spheres showed delayed and extended target gene silencing compared to naked oligonucleotides. The prolonged Stat3 silencing resulted in the more pronounced downregulation of interleukin 6 (IL-6), a proinflammatory cytokine and upstream activator of STAT3, which limits the efficacy of TLR9 immunostimulation. Our results demonstrate the feasibility of using spider silk spheres as a carrier of therapeutic nucleic acids. Moreover, the modified kinetic and activity of the CpG-STAT3siRNA embedded into silk spheres is likely to improve immunotherapeutic effects in vivo. We demonstrated that modification of silk protein by adding the nucleic acid binding domain enabled the development of a novel oligonucleotide delivery system that can be utilized to improve pharmacokinetics of RNA-based therapeutics. Although, the siRNA constructs have already given very promising results in the cancer therapy, the in vivo application of RNA-based oligonucleotide therapeutics still is limited due to their sensitivity to serum nucleases and some toxicity. We propose a carrier for RNA-based therapeutics that is made of bioengineered spider silk. We showed that functionalized bioengineered spider silk spheres not only protected RNA-based therapeutics from degradation by serum nucleases, but what is more important the embedding of siRNA into silk spheres delayed and extended target gene silencing compared with naked oligonucleotides. Moreover, we showed that plain silk spheres did not have unspecific effect on target gene levels proving not only to be non-cytotoxic but also very neutral vehicles in terms of TLR9/STAT3 activation in macrophages. We demonstrated advantages of novel delivery technology in safety and efficacy comparing with delivery of naked CpG-STAT3siRNA therapeutics. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  10. Fiber optics reflectance spectroscopy (45°x: 45°) for color analysis of dental composite.

    PubMed

    Gargano, Marco; Ludwig, Nicola; Federighi, Veronica; Sykes, Ros; Lodi, Giovanni; Sardella, Andrea; Carrassi, Antonio; Varoni, Elena M

    2016-08-01

    To evaluate the application of a fiber optic reflectance spectroscopy (FORS) prototype probe for 45°x: 45° FORS for determining color of dental materials. A portable spectrophotometer with a highly manageable fiber optics co-axial probe was used to apply 45°x: 45° FORS for color matching in restorative dentistry. The color coordinates in CIELAB space of two dental shade guides and of the corresponding photopolymerized composites were collected and compared. The 45°x: 45° FORS with the co-axial probe (test system), the integrating sphere spectroscopy (reference system) and a commercial dental colorimeter (comparator system) were used to collect data and calculate color differences (ΔE and ΔE00). FORS system displayed high repeatability, reproducibility and accuracy. ΔE and ΔE00 values between the shade-guide, each other, and the corresponding composites resulted above the clinically acceptable limit. The 45°x: 45° FORS test system demonstrated suitable in vitro performance for dental composite color evaluation. 45°x: 45° fiber optic reflectance spectroscopy allows reliable color analysis of small surfaces of dental composites, favoring the color matching of material with the closely surrounding dental tissue, and confirming significant color differences between shade guide tabs and photo-polymerized composites.

  11. Light collection device for flame emission detectors

    DOEpatents

    Woodruff, Stephen D.; Logan, Ronald G.; Pineault, Richard L.

    1990-01-01

    A light collection device for use in a flame emission detection system such as an on-line, real-time alkali concentration process stream monitor is disclosed which comprises a sphere coated on its interior with a highly diffuse reflective paint which is positioned over a flame emission source, and one or more fiber optic cables which transfer the light generated at the interior of the sphere to a detecting device. The diffuse scattering of the light emitted by the flame uniformly distributes the light in the sphere, and the collection efficiency of the device is greater than that obtainable in the prior art. The device of the present invention thus provides enhanced sensitivity and reduces the noise associated with flame emission detectors, and can achieve substantial improvements in alkali detection levels.

  12. Hard Sphere Simulation by Event-Driven Molecular Dynamics: Breakthrough, Numerical Difficulty, and Overcoming the issues

    NASA Astrophysics Data System (ADS)

    Isobe, Masaharu

    Hard sphere/disk systems are among the simplest models and have been used to address numerous fundamental problems in the field of statistical physics. The pioneering numerical works on the solid-fluid phase transition based on Monte Carlo (MC) and molecular dynamics (MD) methods published in 1957 represent historical milestones, which have had a significant influence on the development of computer algorithms and novel tools to obtain physical insights. This chapter addresses the works of Alder's breakthrough regarding hard sphere/disk simulation: (i) event-driven molecular dynamics, (ii) long-time tail, (iii) molasses tail, and (iv) two-dimensional melting/crystallization. From a numerical viewpoint, there are serious issues that must be overcome for further breakthrough. Here, we present a brief review of recent progress in this area.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krasniak, S. R.; Smith, R. D.

    Enzymatic hydrolysis of biomass to produce glucose may become feasible if an inexpensive method to reuse the enzyme can be found. This study investigated one such method whereby ..beta..-D-glucosidase (E.C. 3.2.1.21) was immobilized in calcium alginate gel spheres, which were shown to catalyze the hydrolysis of cellobiose to glucose. There was a loss of 49% of the enzyme from the alginate slurry during gelation. After gelation, in the stable gel spheres, there was a 37% retention of the enzyme activity that was actually immobilized. The reason for the loss in activity was investigated and may be caused by inhibition ofmore » the enzyme within the sphere by the calcium cations and the alginate anions also present. Mass transfer effects were minimal in this system and were not responsible for the activity loss.« less

  14. International Energy Agency Ocean Energy Systems Task 10 Wave Energy Converter Modeling Verification and Validation: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wendt, Fabian F; Yu, Yi-Hsiang; Nielsen, Kim

    This is the first joint reference paper for the Ocean Energy Systems (OES) Task 10 Wave Energy Converter modeling verification and validation group. The group is established under the OES Energy Technology Network program under the International Energy Agency. OES was founded in 2001 and Task 10 was proposed by Bob Thresher (National Renewable Energy Laboratory) in 2015 and approved by the OES Executive Committee EXCO in 2016. The kickoff workshop took place in September 2016, wherein the initial baseline task was defined. Experience from similar offshore wind validation/verification projects (OC3-OC5 conducted within the International Energy Agency Wind Task 30)more » [1], [2] showed that a simple test case would help the initial cooperation to present results in a comparable way. A heaving sphere was chosen as the first test case. The team of project participants simulated different numerical experiments, such as heave decay tests and regular and irregular wave cases. The simulation results are presented and discussed in this paper.« less

  15. Minimoon Survey with Subaru Hyper Suprime-Cam

    NASA Astrophysics Data System (ADS)

    Jedicke, Robert; Boe, Ben; Bolin, Bryce T.; Bottke, William; Chyba, Monique; Denneau, Larry; Dodds, Curt; Granvik, Mikael; Kleyna, Jan; Weryk, Robert J.

    2017-10-01

    We will present the status of our search for minimoons using Hyper Suprime-Cam on the Subaru telescope on Maunkea, Hawaii. We use the term 'minimoon' to refer to objects that are gravitationally bound to the Earth-Moon system, make at least one revolution around the barycenter in a co-rotating frame relative to the Earth-Sun axis, and are within 3 Earth Hill-sphere radii (˜12 LD). There are one or two 1 to 2 meter diameter minimoons in the steady state population at any time, and about a dozen larger than 50 cm diameter. `Drifters' are also bound to the Earth-Moon system but make less than one revolution about the barycenter. The combined population of minimoons and drifters provide a new opportunity for scientific exploration of small asteroids and testing concepts for in-situ resource utilization. These objects provide interesting challenges for rendezvous missions because of their limited lifetime and complicated trajectories. Furthermore, they are difficult to detect because they are small, available for a limited time period, and move quickly across the sky.

  16. Statistical Mechanical Theory of Coupled Slow Dynamics in Glassy Polymer-Molecule Mixtures

    NASA Astrophysics Data System (ADS)

    Zhang, Rui; Schweizer, Kenneth

    The microscopic Elastically Collective Nonlinear Langevin Equation theory of activated relaxation in one-component supercooled liquids and glasses is generalized to polymer-molecule mixtures. The key idea is to account for dynamic coupling between molecule and polymer segment motion. For describing the molecule hopping event, a temporal casuality condition is formulated to self-consistently determine a dimensionless degree of matrix distortion relative to the molecule jump distance based on the concept of coupled dynamic free energies. Implementation for real materials employs an established Kuhn sphere model of the polymer liquid and a quantitative mapping to a hard particle reference system guided by the experimental equation-of-state. The theory makes predictions for the mixture dynamic shear modulus, activated relaxation time and diffusivity of both species, and mixture glass transition temperature as a function of molecule-Kuhn segment size ratio and attraction strength, composition and temperature. Model calculations illustrate the dynamical behavior in three distinct mixture regimes (fully miscible, bridging, clustering) controlled by the molecule-polymer interaction or chi-parameter. Applications to specific experimental systems will be discussed.

  17. Water Surface Impact and Ricochet of Deformable Elastomeric Spheres

    NASA Astrophysics Data System (ADS)

    Hurd, Randy C.

    Soft and deformable silicone rubber spheres ricochet from a water surface when rigid spheres and disks (or skipping stones) cannot. This dissertation investigates why these objects are able to skip so successfully. High speed cameras allow us to see that these unique spheres deform significantly as they impact the water surface, flattening into pancake-like shapes with greater area. Though the water entry behavior of deformable spheres deviates from that of rigid spheres, our research shows that if this deformation is accounted for, their behavior can be predicted from previously established methods. Soft spheres skip more easily because they deform significantly when impacting the water surface. We present a diagram which enables the prediction of a ricochet from sphere impact conditions such as speed and angle. Experiments and mathematical representations of the sphere skipping both show that these deformable spheres skip more readily because deformation momentarily increases sphere area and produces an attack angle with the water which is favorable to skipping. Predictions from our mathematical representation of sphere skipping agree strongly with observations from experiments. Even when a sphere was allowed to skip multiple times in the laboratory, the mathematical predictions show good agreement with measured impact conditions through subsequent skipping events. While studying multiple impact events in an outdoor setting, we discovered a previously unidentified means of skipping, which is unique to deformable spheres. This new skipping occurs when a relatively soft sphere first hits the water at a high speed and low impact angle and the sphere begins to rotate very quickly. This quick rotation causes the sphere to stretch into a shape similar to an American football and maintain this shape while it spins. The sphere is observed to move nearly parallel with the water surface with the tips of this "football" dipping into the water as it rotates and the sides passing just over the surface. This sequence of rapid impact events give the impression that the sphere is walking across the water surface.

  18. Collinear swimmer propelling a cargo sphere at low Reynolds number.

    PubMed

    Felderhof, B U

    2014-11-01

    The swimming velocity and rate of dissipation of a linear chain consisting of two or three little spheres and a big sphere is studied on the basis of low Reynolds number hydrodynamics. The big sphere is treated as a passive cargo, driven by the tail of little spheres via hydrodynamic and direct elastic interaction. The fundamental solution of Stokes equations in the presence of a sphere with a no-slip boundary condition, as derived by Oseen, is used to model the hydrodynamic interactions between the big sphere and the little spheres.

  19. The Minnesota Grading System of eye bank eyes for age-related macular degeneration.

    PubMed

    Olsen, Timothy W; Feng, Xiao

    2004-12-01

    The Minnesota Grading System (MGS) is a method to evaluate human eye bank eyes and determine the level of age-related macular degeneration (AMD), by using criteria and definitions from the Age-Related Eye Disease Study (AREDS). Donor eyes (108 pairs) from the Minnesota Lions Eye Bank were cut circumferentially at the pars plana to remove the anterior segment. A 1000 +/- 2.5-microm ruby sphere was placed on the optic nerve as a size reference. A digital, high-resolution, color macular photograph was taken through a dissecting microscope. The neurosensory retina was removed from one globe of the pair. The underlying retinal pigment epithelium was rephotographed, localizing the fovea with a proportional triangle. A grid was superimposed in the macular photographs and images were graded according to AREDS criteria. Twenty pairs were dissected bilaterally and graded for symmetry. Eighty-eight globes were graded into one of four MGS categories. Nineteen (95%) of 20 globes had symmetric grades. The MGS provides a methodology to grade donor tissue from eye bank eyes to correspond to the AREDS classification system. Donor tissue may be used for subsequent molecular analysis, including genomics and proteomics.

  20. A Site Density Functional Theory for Water: Application to Solvation of Amino Acid Side Chains.

    PubMed

    Liu, Yu; Zhao, Shuangliang; Wu, Jianzhong

    2013-04-09

    We report a site density functional theory (SDFT) based on the conventional atomistic models of water and the universality ansatz of the bridge functional. The excess Helmholtz energy functional is formulated in terms of a quadratic expansion with respect to the local density deviation from that of a uniform system and a universal functional for all higher-order terms approximated by that of a reference hard-sphere system. With the atomistic pair direct correlation functions of the uniform system calculated from MD simulation and an analytical expression for the bridge functional from the modified fundamental measure theory, the SDFT can be used to predict the structure and thermodynamic properties of water under inhomogeneous conditions with a computational cost negligible in comparison to that of brute-force simulations. The numerical performance of the SDFT has been demonstrated with the predictions of the solvation free energies of 15 molecular analogs of amino acid side chains in water represented by SPC/E, SPC, and TIP3P models. For theTIP3P model, a comparison of the theoretical predictions with MD simulation and experimental data shows agreement within 0.64 and 1.09 kcal/mol on average, respectively.

  1. Determination of optical coefficients of biological tissue from a single integrating-sphere

    NASA Astrophysics Data System (ADS)

    Zhang, Lianshun; Shi, Aijuan; Lu, Hongguang

    2012-01-01

    The detection of interactions between light and tissue can be used to characterize the optical properties of the tissue. The development is described of a method that determines optical coefficients of biological tissue from a single optical reflectance spectrum measured with an integrating-sphere. The experimental system incorporated a DH-2000 deuterium tungsten halogen light source, a USB4000-VIS-NIR miniature fiber optic spectrometer and an integrating-sphere. Fat emulsion and ink were used to mimic the scattering and absorbing properties of tissue in the tested sample. The measured optical reflectance spectrums with different scattering and absorbing properties were used to train a back-propagation neural network (BPNN). Then the neural network (BPNN) was used to determine the optical coefficients of biological tissue from a single optical reflectance spectrum measured with an integrating-sphere. Tests on tissue-simulation phantoms showed the relative errors of this technique to be 7% for the reduced scattering coefficient and 15% for the absorption coefficients. The optical properties of human skin were also measured in vivo.

  2. Determinants and conformal anomalies of GJMS operators on spheres

    NASA Astrophysics Data System (ADS)

    Dowker, J. S.

    2011-03-01

    The conformal anomalies and functional determinants of the Branson-GJMS operators, P2k, on the d-dimensional sphere are evaluated in explicit terms for any d and k such that k <= d/2 (if d is even). The determinants are given in terms of multiple gamma functions and a rational multiplicative anomaly, which vanishes for odd d. Taking the mode system on the sphere as the union of Neumann and Dirichlet ones on the hemisphere is a basic part of the method and leads to a heuristic explanation of the non-existence of 'super-critical' operators, 2k > d for even d. Significant use is made of the Barnes zeta function. The results are given in terms of ratios of determinants of operators on a (d + 1)-dimensional bulk dual sphere. For odd dimensions, the log determinant is written in terms of multiple sine functions and agreement is found with holographic computations, yielding an integral over a Plancherel measure. The N-D determinant ratio is also found explicitly for even dimensions. Ehrhart polynomials are encountered.

  3. Fluids in porous media. IV. Quench effect on chemical potential.

    PubMed

    Qiao, C Z; Zhao, S L; Liu, H L; Dong, W

    2017-06-21

    It appears to be a common sense to measure the crowdedness of a fluid system by the densities of the species constituting it. In the present work, we show that this ceases to be valid for confined fluids under some conditions. A quite thorough investigation is made for a hard sphere (HS) fluid adsorbed in a hard sphere matrix (a quench-annealed system) and its corresponding equilibrium binary mixture. When fluid particles are larger than matrix particles, the quench-annealed system can appear much more crowded than its corresponding equilibrium binary mixture, i.e., having a much higher fluid chemical potential, even when the density of each species is strictly the same in both systems, respectively. We believe that the insight gained from this study should be useful for the design of functionalized porous materials.

  4. Critical Steps in Data Analysis for Precision Casimir Force Measurements with Semiconducting Films

    NASA Astrophysics Data System (ADS)

    Banishev, A. A.; Chang, Chia-Cheng; Mohideen, U.

    2011-06-01

    Some experimental procedures and corresponding results of the precision measurement of the Casimir force between low doped Indium Tin Oxide (ITO) film and gold sphere are described. Measurements were performed using an Atomic Force Microscope in high vacuum. It is shown that the magnitude of the Casimir force decreases after prolonged UV treatment of the ITO film. Some critical data analysis steps such as the correction for the mechanical drift of the sphere-plate system and photodiodes are discussed.

  5. Critical Steps in Data Analysis for Precision Casimir Force Measurements with Semiconducting Films

    NASA Astrophysics Data System (ADS)

    Banishev, A. A.; Chang, Chia-Cheng; Mohideen, U.

    Some experimental procedures and corresponding results of the precision measurement of the Casimir force between low doped Indium Tin Oxide (ITO) film and gold sphere are described. Measurements were performed using an Atomic Force Microscope in high vacuum. It is shown that the magnitude of the Casimir force decreases after prolonged UV treatment of the ITO film. Some critical data analysis steps such as the correction for the mechanical drift of the sphere-plate system and photodiodes are discussed.

  6. Acquisition of Long-Duration, Low-Gravity Slosh Data Utilizing Existing ISS Equipment (SPHERES) for Calibration of CFD Models of Coupled Fluid-Vehicle Behavior

    NASA Technical Reports Server (NTRS)

    Schallhorn, Paul; Roth, Jacob; Marsell, Brandon; Kirk, Daniel; Gutierrez, Hector; Saenz-Otero, Alvar; Dorney, Daniel; Moder, Jeffrey

    2013-01-01

    Accurate prediction of coupled fluid slosh and launch vehicle or spacecraft dynamics (e.g., nutation/precessional movement about various axes, attitude changes, ect.) requires Computational Fluid Dynamics (CFD) models calibrated with low-gravity, long duration slosh data. Recently completed investigations of reduced gravity slosh behavior have demonstrated the limitations of utilizing parabolic flights on specialized aircraft with respect to the specific objectives of the experiments. Although valuable data was collected, the benefits of longer duration low-gravity environments were clearly established. The proposed research provides the first data set from long duration tests in zero gravity that can be directly used to benchmark CFD models, including the interaction between the sloshing fluid and the tank/vehicle dynamics. To explore the coupling of liquid slosh with the motion of an unconstrained tank in microgravity, NASA's Kennedy Space Center, Launch Services Program has teamed up with the Florida Institute of Technology (FIT), Massachusetts Institute of Technology (MIT) and the NASA Game Changing Development Program (GCD) to perform a series of slosh dynamics experiments on the International Space Station using the SPHERES platform. The Synchronized Position Hold Engage Reorient Experimental Satellites (SPHERES) testbed provides a unique, free-floating instrumented platform on ISS that can be utilized in a manner that would solve many of the limitations of the current knowledge related to propellant slosh dynamics on launch vehicle and spacecraft fuel tanks. The six degree of freedom (6-DOF) motion of the SPHERES free-flyer is controlled by an array of cold-flow C02 thrusters, supplied from a built-in liquid C02 tank. These SPHERES can independently navigate and re-orient themselves within the ISS. The intent of this project is to design an externally mounted tank to be driven inside the ISS by a set of two SPHERES devices (Figure 1). The tank geometry simulates a launch vehicle upper stage propellant tank and the maneuvers replicate those of real vehicles. The design includes inertial sensors, data acquisition, image capture and data storage interfaces to the SPHERES VERTIGO computer system on board the flight article assembly. The design also includes mechanical and electronic interfaces to the existing SPHERES hardware, which include self-contained packages that can operate in conjunction with the existing SPHERES electronics

  7. Acquisition of Long-Duration, Low-Gravity Slosh Data Utilizing Existing ISS Equipment (SPHERES) for Calibration of CFD Models of Coupled Fluid-Vehicle Behavior

    NASA Technical Reports Server (NTRS)

    Schallhorn, Paul; Roth, Jacob; Marsell, Brandon; Kirk, Daniel; Gutierrez, Hector; Saenz-Otero, Alvar; Dorney, Daniel; Moder, Jeffrey

    2012-01-01

    Accurate prediction of coupled fluid slosh and launch vehicle or spacecraft dynamics (e.g., nutation/precessional movement about various axes, attitude changes, ect.) requires Computational Fluid Dynamics (CFD) models calibrated with low-gravity, long duration slosh data. Recently completed investigations of reduced gravity slosh behavior have demonstrated the limitations of utilizing parabolic flights on specialized aircraft with respect to the specific objectives of the experiments. Although valuable data was collected, the benefits of longer duration low-gravity environments were clearly established. The proposed research provides the first data set from long duration tests in zero gravity that can be directly used to benchmark CFD models, including the interaction between the sloshing fluid and the tank/vehicle dynamics. To explore the coupling of liquid slosh with the motion of an unconstrained tank in microgravity, NASA's Kennedy Space Center, Launch Services Program has teamed up with the Florida Institute of Technology (FIT), Massachusetts Institute of Technology (MIT) and the Office of the Chief Technologist (OCT) to perform a series of slosh dynamics experiments on the International Space Station using the SPHERES platform. The Synchronized Position Hold Engage Reorient Experimental Satellites (SPHERES) testbed provides a unique, free-floating instrumented platform on ISS that can be utilized in a manner that would solve many of the limitations of the current knowledge related to propellant slosh dynamics on launch vehicle and spacecraft fuel tanks. The six degree of freedom (6-DOF) motion of the SPHERES free-flyer is controlled by an array of cold-flow C02 thrusters, supplied from a built-in liquid C02 tank. These SPHERES can independently navigate and re-orient themselves within the ISS. The intent of this project is to design an externally mounted tank to be driven inside the ISS by a set of two SPHERES devices (Figure 1 ). The tank geometry simulates a launch vehicle upper stage propellant tank and the maneuvers replicate those of real vehicles. The design includes inertial sensors, data acquisition, image capture and data storage interfaces to the SPHERES VERTIGO computer system on board the flight article assembly. The design also includes mechanical and electronic interfaces to the existing SPHERES hardware, which include self-contained packages that can operate in conjunction with the existing SPHERES electronics.

  8. Stem/progenitor cells derived from the cochlear sensory epithelium give rise to spheres with distinct morphologies and features.

    PubMed

    Diensthuber, Marc; Oshima, Kazuo; Heller, Stefan

    2009-06-01

    Nonmammalian vertebrates regenerate lost sensory hair cells by means of asymmetric division of supporting cells. Inner ear or lateral line supporting cells in birds, amphibians, and fish consequently serve as bona fide stem cells resulting in high regenerative capacity of hair cell-bearing organs. Hair cell regeneration does not happen in the mammalian cochlea, but cells with proliferative capacity can be isolated from the neonatal cochlea. These cells have the ability to form clonal floating colonies, so-called spheres, when cultured in nonadherent conditions. We noticed that the sphere population derived from mouse cochlear sensory epithelium cells was heterogeneous, consisting of morphologically distinct sphere types, hereby classified as solid, transitional, and hollow. Cochlear sensory epithelium-derived stem/progenitor cells initially give rise to small solid spheres, which subsequently transition into hollow spheres, a change that is accompanied by epithelial differentiation of the majority of sphere cells. Only solid spheres, and to a lesser extent, transitional spheres, appeared to harbor self-renewing stem cells, whereas hollow spheres could not be consistently propagated. Solid spheres contained significantly more rapidly cycling Pax-2-expressing presumptive otic progenitor cells than hollow spheres. Islet-1, which becomes upregulated in nascent sensory patches, was also more abundant in solid than in hollow spheres. Likewise, hair cell-like cells, characterized by the expression of multiple hair cell markers, differentiated in significantly higher numbers in cell populations derived from solid spheres. We conclude that cochlear sensory epithelium cell populations initially give rise to small solid spheres that have self-renewing capacity before they subsequently convert into hollow spheres, a process that is accompanied by loss of stemness and reduced ability to spontaneously give rise to hair cell-like cells. Solid spheres might, therefore, represent the most suitable sphere type for cell-based assays or animal model transplantation studies aimed at development of cell replacement therapies.

  9. Characterisation of FAP-1 expression and CD95 mediated apoptosis in the A818-6 pancreatic adenocarcinoma differentiation system.

    PubMed

    Winterhoff, Boris J N; Arlt, Alexander; Duttmann, Angelika; Ungefroren, Hendrik; Schäfer, Heiner; Kalthoff, Holger; Kruse, Marie-Luise

    2012-03-01

    The present study investigated the expression and localisation of FAP-1 (Fas associated phosphatase-1) and CD95 in a 3D differentiation model in comparison to 2D monolayers of the pancreatic adenocarcinoma cell line A818-6. Under non-adherent growth conditions, A818-6 cells differentiate into 3D highly organised polarised epithelial hollow spheres, resembling duct-like structures. A818-6 cells showed a differentiation-dependent FAP-1 localisation. Cells grown as 2D monolayers revealed FAP-1 staining in a juxtanuclear cisternal position, as well as localisation in the nucleus. After differentiation into hollow spheres, FAP-1 was relocated towards the actin cytoskeleton beneath the outer plasma membrane of polarised cells and no further nuclear localisation was observed. CD95 surface staining was found only in a subset of A818-6 monolayer cells, while differentiated hollow spheres appeared to express CD95 in all cells of a given sphere. We rarely observed co-localisation of CD95 and FAP-1 in A818-6 monolayer cells, but strong co-localisation beneath the outer plasma membrane in polarised cells. Analysis of surface expression by flow cytometry revealed that only a subset (36%) of monolayer cells showed CD95 surface expression, and after induction of hollow spheres, CD95 presentation at the outer plasma membrane was reduced to 13% of hollow spheres. Induction of apoptosis by stimulation with agonistic anti-CD95 antibodies, resulted in increased caspase activity in both, monolayer cells and hollow spheres. Knock down of FAP-1 mRNA in A818-6 monolayer cells did not alter resposiveness to CD95 agonistic antibodies. These data suggested that CD95 signal transduction was not affected by FAP-1 expression in A818-6 monolayer cells. In differentiated 3D hollow spheres, we found a polarisation-induced co-localisation of CD95 and FAP-1. A tight control of receptor surface representation and signalling induced apoptosis ensures controlled removal of individual cells instead of a "snowball effect" of apoptotic events. Copyright © 2011 International Society of Differentiation. Published by Elsevier B.V. All rights reserved.

  10. Role of Polymer-grafted Nanoparticle Interactions in Supercrystal Self-Assembly

    NASA Astrophysics Data System (ADS)

    Horst, Nathan; Waltmann, Curt; Travesset, Alex

    Many successful strategies are available for the programmable self-assembly of nanoparticle superlattices. In this talk, we discuss the the case of nanoparticles with grafted polymer ligands. For very short polymers, the phase diagram is rationalized by borrowing results from hard-sphere packing models. Although a clear correlation exists between the maximum of the packing fraction of hard spheres and supercrystal equilibrium phases found experimentally, these systems are flexible, which leads to clear deviations from the sphere packing model. Using theoretical and computational models, we present an investigation of the interactions of polymer-grafted nanoparticles, focusing on the role of the rigidity of the chain, and how it affects the resulting two and three-dimensional superlattice structures. Comparison with an experimental system of gold nanoparticles grafted with polyethylene glycol is also presented. Supported by the U.S. Department of Energy (U.S. DOE), Office of Basic Energy Sciences, Division of Materials Sciences and Engineering. Ames Laboratory is operated for the U.S. DOE by Iowa State University under Contract No. DE-AC02-07CH11358.

  11. Pressure and compressibility factor of bidisperse magnetic fluids

    NASA Astrophysics Data System (ADS)

    Minina, Elena S.; Blaak, Ronald; Kantorovich, Sofia S.

    2018-04-01

    In this work, we investigate the pressure and compressibility factors of bidisperse magnetic fluids with relatively weak dipolar interactions and different granulometric compositions. In order to study these properties, we employ the method of diagram expansion, taking into account two possible scenarios: (1) dipolar particles repel each other as hard spheres; (2) the polymer shell on the surface of the particles is modelled through a soft-sphere approximation. The theoretical predictions of the pressure and compressibility factors of bidisperse ferrofluids at different granulometric compositions are supported by data obtained by means of molecular dynamics computer simulations, which we also carried out for these systems. Both theory and simulations reveal that the pressure and compressibility factors decrease with growing dipolar correlations in the system, namely with an increasing fraction of large particles. We also demonstrate that even if dipolar interactions are too weak for any self-assembly to take place, the interparticle correlations lead to a qualitative change in the behaviour of the compressibility factors when compared to that of non-dipolar spheres, making the dependence monotonic.

  12. Equation of state and Helmholtz free energy for the atomic system of the repulsive Lennard-Jones particles.

    PubMed

    Mirzaeinia, Ali; Feyzi, Farzaneh; Hashemianzadeh, Seyed Majid

    2017-12-07

    Simple and accurate expressions are presented for the equation of state (EOS) and absolute Helmholtz free energy of a system composed of simple atomic particles interacting through the repulsive Lennard-Jones potential model in the fluid and solid phases. The introduced EOS has 17 and 22 coefficients for fluid and solid phases, respectively, which are regressed to the Monte Carlo (MC) simulation data over the reduced temperature range of 0.6≤T * ≤6.0 and the packing fraction range of 0.1 ≤ η ≤ 0.72. The average absolute relative percent deviation in fitting the EOS parameters to the MC data is 0.06 and 0.14 for the fluid and solid phases, respectively. The thermodynamic integration method is used to calculate the free energy using the MC simulation results. The Helmholtz free energy of the ideal gas is employed as the reference state for the fluid phase. For the solid phase, the values of the free energy at the reduced density equivalent to the close-packed of a hard sphere are used as the reference state. To check the validity of the predicted values of the Helmholtz free energy, the Widom particle insertion method and the Einstein crystal technique of Frenkel and Ladd are employed. The results obtained from the MC simulation approaches are well agreed to the EOS results, which show that the proposed model can reliably be utilized in the framework of thermodynamic theories.

  13. Equation of state and Helmholtz free energy for the atomic system of the repulsive Lennard-Jones particles

    NASA Astrophysics Data System (ADS)

    Mirzaeinia, Ali; Feyzi, Farzaneh; Hashemianzadeh, Seyed Majid

    2017-12-01

    Simple and accurate expressions are presented for the equation of state (EOS) and absolute Helmholtz free energy of a system composed of simple atomic particles interacting through the repulsive Lennard-Jones potential model in the fluid and solid phases. The introduced EOS has 17 and 22 coefficients for fluid and solid phases, respectively, which are regressed to the Monte Carlo (MC) simulation data over the reduced temperature range of 0.6 ≤T*≤6.0 and the packing fraction range of 0.1 ≤ η ≤ 0.72. The average absolute relative percent deviation in fitting the EOS parameters to the MC data is 0.06 and 0.14 for the fluid and solid phases, respectively. The thermodynamic integration method is used to calculate the free energy using the MC simulation results. The Helmholtz free energy of the ideal gas is employed as the reference state for the fluid phase. For the solid phase, the values of the free energy at the reduced density equivalent to the close-packed of a hard sphere are used as the reference state. To check the validity of the predicted values of the Helmholtz free energy, the Widom particle insertion method and the Einstein crystal technique of Frenkel and Ladd are employed. The results obtained from the MC simulation approaches are well agreed to the EOS results, which show that the proposed model can reliably be utilized in the framework of thermodynamic theories.

  14. Climate Solutions Presentations on Science On a Sphere (SOS) and SOS Explorer achieve acceptance of Climate Science among Policymakers as well as the Public: US National Academy of Sciences Symposium/Open House Example

    NASA Astrophysics Data System (ADS)

    Sievering, H.

    2015-12-01

    The outcomes of climate science are inherently rife with discussions of dire consequences for humans that leave many listeners feeling helpless and hopeless. We have found that a focus on clean energy solutions, without reference to dirty energy, substantially reduces (may even eliminate) the negativity associated with sea level rise, extreme weather and other climate change presentations. US audiences respond well to discussion of California's clean energy transformation with solar, wind, geothermal and water power together now approaching 25% of total energy supply for the world's sixth largest economy. For both policymakers and the general public, a "positive climate change" presentation does not generally suffice on its own. Clear visual display of climate science information is essential. We have found the Science On a Sphere (SOS) National Oceanic and Atmospheric Administration science education tool, to be exceptional in this regard. Further, broad dissemination is possible given the SOS network consists of over 120 sites in 23 countries. The new SOS Explorer system, an advanced science education tool, can readily utilize the over 500 available SOS data sets. We have recently developed an arctic amplification and mid-latitude climate change impacts program for the upcoming US National Academy of Sciences' Arctic Matters Symposium/Open House. This SOS and SOS Explorer education program will be described with emphasis on the climate solutions incorporated into this module targeted at US policymakers and invited open house public.

  15. Random close packing of disks and spheres in confined geometries

    NASA Astrophysics Data System (ADS)

    Desmond, Kenneth W.; Weeks, Eric R.

    2009-11-01

    Studies of random close packing of spheres have advanced our knowledge about the structure of systems such as liquids, glasses, emulsions, granular media, and amorphous solids. In confined geometries, the structural properties of random-packed systems will change. To understand these changes, we study random close packing in finite-sized confined systems, in both two and three dimensions. Each packing consists of a 50-50 binary mixture with particle size ratio of 1.4. The presence of confining walls significantly lowers the overall maximum area fraction (or volume fraction in three dimensions). A simple model is presented, which quantifies the reduction in packing due to wall-induced structure. This wall-induced structure decays rapidly away from the wall, with characteristic length scales comparable to the small particle diameter.

  16. Collective motion of macroscopic spheres floating on capillary ripples: Dynamic heterogeneity and dynamic criticality

    NASA Astrophysics Data System (ADS)

    Sanlı, Ceyda; Saitoh, Kuniyasu; Luding, Stefan; van der Meer, Devaraj

    2014-09-01

    When a densely packed monolayer of macroscopic spheres floats on chaotic capillary Faraday waves, a coexistence of large scale convective motion and caging dynamics typical for glassy systems is observed. We subtract the convective mean flow using a coarse graining (homogenization) method and reveal subdiffusion for the caging time scales followed by a diffusive regime at later times. We apply the methods developed to study dynamic heterogeneity and show that the typical time and length scales of the fluctuations due to rearrangements of observed particle groups significantly increase when the system approaches its largest experimentally accessible packing concentration. To connect the system to the dynamic criticality literature, we fit power laws to our results. The resultant critical exponents are consistent with those found in densely packed suspensions of colloids.

  17. Collective motion of macroscopic spheres floating on capillary ripples: dynamic heterogeneity and dynamic criticality.

    PubMed

    Sanlı, Ceyda; Saitoh, Kuniyasu; Luding, Stefan; van der Meer, Devaraj

    2014-09-01

    When a densely packed monolayer of macroscopic spheres floats on chaotic capillary Faraday waves, a coexistence of large scale convective motion and caging dynamics typical for glassy systems is observed. We subtract the convective mean flow using a coarse graining (homogenization) method and reveal subdiffusion for the caging time scales followed by a diffusive regime at later times. We apply the methods developed to study dynamic heterogeneity and show that the typical time and length scales of the fluctuations due to rearrangements of observed particle groups significantly increase when the system approaches its largest experimentally accessible packing concentration. To connect the system to the dynamic criticality literature, we fit power laws to our results. The resultant critical exponents are consistent with those found in densely packed suspensions of colloids.

  18. Measurement of the Casimir Force between Two Spheres

    NASA Astrophysics Data System (ADS)

    Garrett, Joseph L.; Somers, David A. T.; Munday, Jeremy N.

    2018-01-01

    Complex interaction geometries offer a unique opportunity to modify the strength and sign of the Casimir force. However, measurements have traditionally been limited to sphere-plate or plate-plate configurations. Prior attempts to extend measurements to different geometries relied on either nanofabrication techniques that are limited to only a few materials or slight modifications of the sphere-plate geometry due to alignment difficulties of more intricate configurations. Here, we overcome this obstacle to present measurements of the Casimir force between two gold spheres using an atomic force microscope. Force measurements are alternated with topographical scans in the x -y plane to maintain alignment of the two spheres to within approximately 400 nm (˜1 % of the sphere radii). Our experimental results are consistent with Lifshitz's theory using the proximity force approximation (PFA), and corrections to the PFA are bounded using nine sphere-sphere and three sphere-plate measurements with spheres of varying radii.

  19. Capillary spreading of contact line over a sinking sphere

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Seong Jin; Fezzaa, Kamel; An, Jim

    The contact line dynamics over a sinking solid sphere are investigated in comparison with classical spreading theories. Experimentally, high-speed imaging systems with optical light or x-ray illumination are employed to accurately measure the spreading motion and dynamic contact angle of the contact line. Millimetric spheres are controlled to descend with a constant speed ranging from 7.3 × 10-5 to 0.79 m/s. We observed three different spreading stages over a sinking sphere, which depends on the contact line velocity and contact angle. These stages consistently showed the characteristics of capillarity-driven spreading as the contact line spreads faster with a higher contactmore » angle. The contact line velocity is observed to follow a classical capillary-viscous model at a high Ohnesorge number (> 0.02). For the cases with a relatively low Ohnesorge number (< 0.02), the contact line velocity is significantly lower than the speed predicted by the capillary-viscous balance. This indicates the existence of an additional opposing force (inertia) for a decreasing Ohnesorge number. The capillary-inertial balance is only observed at the very beginning of the capillary rise, in which the maximum velocity is independent of the sphere’s sinking speed. Additionally, we observed the linear relation between the contact line velocity and the sphere sinking speed during the second stage, which represents capillary adjustment by dynamic contact angle.« less

  20. The Enskog Equation for Confined Elastic Hard Spheres

    NASA Astrophysics Data System (ADS)

    Maynar, P.; García de Soria, M. I.; Brey, J. Javier

    2018-03-01

    A kinetic equation for a system of elastic hard spheres or disks confined by a hard wall of arbitrary shape is derived. It is a generalization of the modified Enskog equation in which the effects of the confinement are taken into account and it is supposed to be valid up to moderate densities. From the equation, balance equations for the hydrodynamic fields are derived, identifying the collisional transfer contributions to the pressure tensor and heat flux. A Lyapunov functional, H[f], is identified. For any solution of the kinetic equation, H decays monotonically in time until the system reaches the inhomogeneous equilibrium distribution, that is a Maxwellian distribution with a density field consistent with equilibrium statistical mechanics.

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