Sample records for split bregman techniques

  1. Real-Time Compressive Sensing MRI Reconstruction Using GPU Computing and Split Bregman Methods

    PubMed Central

    Smith, David S.; Gore, John C.; Yankeelov, Thomas E.; Welch, E. Brian

    2012-01-01

    Compressive sensing (CS) has been shown to enable dramatic acceleration of MRI acquisition in some applications. Being an iterative reconstruction technique, CS MRI reconstructions can be more time-consuming than traditional inverse Fourier reconstruction. We have accelerated our CS MRI reconstruction by factors of up to 27 by using a split Bregman solver combined with a graphics processing unit (GPU) computing platform. The increases in speed we find are similar to those we measure for matrix multiplication on this platform, suggesting that the split Bregman methods parallelize efficiently. We demonstrate that the combination of the rapid convergence of the split Bregman algorithm and the massively parallel strategy of GPU computing can enable real-time CS reconstruction of even acquisition data matrices of dimension 40962 or more, depending on available GPU VRAM. Reconstruction of two-dimensional data matrices of dimension 10242 and smaller took ~0.3 s or less, showing that this platform also provides very fast iterative reconstruction for small-to-moderate size images. PMID:22481908

  2. Real-Time Compressive Sensing MRI Reconstruction Using GPU Computing and Split Bregman Methods.

    PubMed

    Smith, David S; Gore, John C; Yankeelov, Thomas E; Welch, E Brian

    2012-01-01

    Compressive sensing (CS) has been shown to enable dramatic acceleration of MRI acquisition in some applications. Being an iterative reconstruction technique, CS MRI reconstructions can be more time-consuming than traditional inverse Fourier reconstruction. We have accelerated our CS MRI reconstruction by factors of up to 27 by using a split Bregman solver combined with a graphics processing unit (GPU) computing platform. The increases in speed we find are similar to those we measure for matrix multiplication on this platform, suggesting that the split Bregman methods parallelize efficiently. We demonstrate that the combination of the rapid convergence of the split Bregman algorithm and the massively parallel strategy of GPU computing can enable real-time CS reconstruction of even acquisition data matrices of dimension 4096(2) or more, depending on available GPU VRAM. Reconstruction of two-dimensional data matrices of dimension 1024(2) and smaller took ~0.3 s or less, showing that this platform also provides very fast iterative reconstruction for small-to-moderate size images.

  3. Split Bregman multicoil accelerated reconstruction technique: A new framework for rapid reconstruction of cardiac perfusion MRI

    PubMed Central

    Kamesh Iyer, Srikant; Tasdizen, Tolga; Likhite, Devavrat; DiBella, Edward

    2016-01-01

    Purpose: Rapid reconstruction of undersampled multicoil MRI data with iterative constrained reconstruction method is a challenge. The authors sought to develop a new substitution based variable splitting algorithm for faster reconstruction of multicoil cardiac perfusion MRI data. Methods: The new method, split Bregman multicoil accelerated reconstruction technique (SMART), uses a combination of split Bregman based variable splitting and iterative reweighting techniques to achieve fast convergence. Total variation constraints are used along the spatial and temporal dimensions. The method is tested on nine ECG-gated dog perfusion datasets, acquired with a 30-ray golden ratio radial sampling pattern and ten ungated human perfusion datasets, acquired with a 24-ray golden ratio radial sampling pattern. Image quality and reconstruction speed are evaluated and compared to a gradient descent (GD) implementation and to multicoil k-t SLR, a reconstruction technique that uses a combination of sparsity and low rank constraints. Results: Comparisons based on blur metric and visual inspection showed that SMART images had lower blur and better texture as compared to the GD implementation. On average, the GD based images had an ∼18% higher blur metric as compared to SMART images. Reconstruction of dynamic contrast enhanced (DCE) cardiac perfusion images using the SMART method was ∼6 times faster than standard gradient descent methods. k-t SLR and SMART produced images with comparable image quality, though SMART was ∼6.8 times faster than k-t SLR. Conclusions: The SMART method is a promising approach to reconstruct good quality multicoil images from undersampled DCE cardiac perfusion data rapidly. PMID:27036592

  4. Split Bregman's optimization method for image construction in compressive sensing

    NASA Astrophysics Data System (ADS)

    Skinner, D.; Foo, S.; Meyer-Bäse, A.

    2014-05-01

    The theory of compressive sampling (CS) was reintroduced by Candes, Romberg and Tao, and D. Donoho in 2006. Using a priori knowledge that a signal is sparse, it has been mathematically proven that CS can defY Nyquist sampling theorem. Theoretically, reconstruction of a CS image relies on the minimization and optimization techniques to solve this complex almost NP-complete problem. There are many paths to consider when compressing and reconstructing an image but these methods have remained untested and unclear on natural images, such as underwater sonar images. The goal of this research is to perfectly reconstruct the original sonar image from a sparse signal while maintaining pertinent information, such as mine-like object, in Side-scan sonar (SSS) images. Goldstein and Osher have shown how to use an iterative method to reconstruct the original image through a method called Split Bregman's iteration. This method "decouples" the energies using portions of the energy from both the !1 and !2 norm. Once the energies are split, Bregman iteration is used to solve the unconstrained optimization problem by recursively solving the problems simultaneously. The faster these two steps or energies can be solved then the faster the overall method becomes. While the majority of CS research is still focused on the medical field, this paper will demonstrate the effectiveness of the Split Bregman's methods on sonar images.

  5. Superiorization-based multi-energy CT image reconstruction

    PubMed Central

    Yang, Q; Cong, W; Wang, G

    2017-01-01

    The recently-developed superiorization approach is efficient and robust for solving various constrained optimization problems. This methodology can be applied to multi-energy CT image reconstruction with the regularization in terms of the prior rank, intensity and sparsity model (PRISM). In this paper, we propose a superiorized version of the simultaneous algebraic reconstruction technique (SART) based on the PRISM model. Then, we compare the proposed superiorized algorithm with the Split-Bregman algorithm in numerical experiments. The results show that both the Superiorized-SART and the Split-Bregman algorithms generate good results with weak noise and reduced artefacts. PMID:28983142

  6. Total-variation based velocity inversion with Bregmanized operator splitting algorithm

    NASA Astrophysics Data System (ADS)

    Zand, Toktam; Gholami, Ali

    2018-04-01

    Many problems in applied geophysics can be formulated as a linear inverse problem. The associated problems, however, are large-scale and ill-conditioned. Therefore, regularization techniques are needed to be employed for solving them and generating a stable and acceptable solution. We consider numerical methods for solving such problems in this paper. In order to tackle the ill-conditioning of the problem we use blockiness as a prior information of the subsurface parameters and formulate the problem as a constrained total variation (TV) regularization. The Bregmanized operator splitting (BOS) algorithm as a combination of the Bregman iteration and the proximal forward backward operator splitting method is developed to solve the arranged problem. Two main advantages of this new algorithm are that no matrix inversion is required and that a discrepancy stopping criterion is used to stop the iterations, which allow efficient solution of large-scale problems. The high performance of the proposed TV regularization method is demonstrated using two different experiments: 1) velocity inversion from (synthetic) seismic data which is based on Born approximation, 2) computing interval velocities from RMS velocities via Dix formula. Numerical examples are presented to verify the feasibility of the proposed method for high-resolution velocity inversion.

  7. Brain vascular image enhancement based on gradient adjust with split Bregman

    NASA Astrophysics Data System (ADS)

    Liang, Xiao; Dong, Di; Hui, Hui; Zhang, Liwen; Fang, Mengjie; Tian, Jie

    2016-04-01

    Light Sheet Microscopy is a high-resolution fluorescence microscopic technique which enables to observe the mouse brain vascular network clearly with immunostaining. However, micro-vessels are stained with few fluorescence antibodies and their signals are much weaker than large vessels, which make micro-vessels unclear in LSM images. In this work, we developed a vascular image enhancement method to enhance micro-vessel details which should be useful for vessel statistics analysis. Since gradient describes the edge information of the vessel, the main idea of our method is to increase the gradient values of the enhanced image to improve the micro-vessels contrast. Our method contained two steps: 1) calculate the gradient image of LSM image, and then amplify high gradient values of the original image to enhance the vessel edge and suppress low gradient values to remove noises. Then we formulated a new L1-norm regularization optimization problem to find an image with the expected gradient while keeping the main structure information of the original image. 2) The split Bregman iteration method was used to deal with the L1-norm regularization problem and generate the final enhanced image. The main advantage of the split Bregman method is that it has both fast convergence and low memory cost. In order to verify the effectiveness of our method, we applied our method to a series of mouse brain vascular images acquired from a commercial LSM system in our lab. The experimental results showed that our method could greatly enhance micro-vessel edges which were unclear in the original images.

  8. Iterative Nonlocal Total Variation Regularization Method for Image Restoration

    PubMed Central

    Xu, Huanyu; Sun, Quansen; Luo, Nan; Cao, Guo; Xia, Deshen

    2013-01-01

    In this paper, a Bregman iteration based total variation image restoration algorithm is proposed. Based on the Bregman iteration, the algorithm splits the original total variation problem into sub-problems that are easy to solve. Moreover, non-local regularization is introduced into the proposed algorithm, and a method to choose the non-local filter parameter locally and adaptively is proposed. Experiment results show that the proposed algorithms outperform some other regularization methods. PMID:23776560

  9. Fractional Diffusion, Low Exponent Lévy Stable Laws, and 'Slow Motion' Denoising of Helium Ion Microscope Nanoscale Imagery.

    PubMed

    Carasso, Alfred S; Vladár, András E

    2012-01-01

    Helium ion microscopes (HIM) are capable of acquiring images with better than 1 nm resolution, and HIM images are particularly rich in morphological surface details. However, such images are generally quite noisy. A major challenge is to denoise these images while preserving delicate surface information. This paper presents a powerful slow motion denoising technique, based on solving linear fractional diffusion equations forward in time. The method is easily implemented computationally, using fast Fourier transform (FFT) algorithms. When applied to actual HIM images, the method is found to reproduce the essential surface morphology of the sample with high fidelity. In contrast, such highly sophisticated methodologies as Curvelet Transform denoising, and Total Variation denoising using split Bregman iterations, are found to eliminate vital fine scale information, along with the noise. Image Lipschitz exponents are a useful image metrology tool for quantifying the fine structure content in an image. In this paper, this tool is applied to rank order the above three distinct denoising approaches, in terms of their texture preserving properties. In several denoising experiments on actual HIM images, it was found that fractional diffusion smoothing performed noticeably better than split Bregman TV, which in turn, performed slightly better than Curvelet denoising.

  10. X-ray luminescence computed tomography imaging based on X-ray distribution model and adaptively split Bregman method

    PubMed Central

    Chen, Dongmei; Zhu, Shouping; Cao, Xu; Zhao, Fengjun; Liang, Jimin

    2015-01-01

    X-ray luminescence computed tomography (XLCT) has become a promising imaging technology for biological application based on phosphor nanoparticles. There are mainly three kinds of XLCT imaging systems: pencil beam XLCT, narrow beam XLCT and cone beam XLCT. Narrow beam XLCT can be regarded as a balance between the pencil beam mode and the cone-beam mode in terms of imaging efficiency and image quality. The collimated X-ray beams are assumed to be parallel ones in the traditional narrow beam XLCT. However, we observe that the cone beam X-rays are collimated into X-ray beams with fan-shaped broadening instead of parallel ones in our prototype narrow beam XLCT. Hence we incorporate the distribution of the X-ray beams in the physical model and collected the optical data from only two perpendicular directions to further speed up the scanning time. Meanwhile we propose a depth related adaptive regularized split Bregman (DARSB) method in reconstruction. The simulation experiments show that the proposed physical model and method can achieve better results in the location error, dice coefficient, mean square error and the intensity error than the traditional split Bregman method and validate the feasibility of method. The phantom experiment can obtain the location error less than 1.1 mm and validate that the incorporation of fan-shaped X-ray beams in our model can achieve better results than the parallel X-rays. PMID:26203388

  11. Regularization iteration imaging algorithm for electrical capacitance tomography

    NASA Astrophysics Data System (ADS)

    Tong, Guowei; Liu, Shi; Chen, Hongyan; Wang, Xueyao

    2018-03-01

    The image reconstruction method plays a crucial role in real-world applications of the electrical capacitance tomography technique. In this study, a new cost function that simultaneously considers the sparsity and low-rank properties of the imaging targets is proposed to improve the quality of the reconstruction images, in which the image reconstruction task is converted into an optimization problem. Within the framework of the split Bregman algorithm, an iterative scheme that splits a complicated optimization problem into several simpler sub-tasks is developed to solve the proposed cost function efficiently, in which the fast-iterative shrinkage thresholding algorithm is introduced to accelerate the convergence. Numerical experiment results verify the effectiveness of the proposed algorithm in improving the reconstruction precision and robustness.

  12. Image Reconstruction from Under sampled Fourier Data Using the Polynomial Annihilation Transform

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Archibald, Richard K.; Gelb, Anne; Platte, Rodrigo

    Fourier samples are collected in a variety of applications including magnetic resonance imaging and synthetic aperture radar. The data are typically under-sampled and noisy. In recent years, l 1 regularization has received considerable attention in designing image reconstruction algorithms from under-sampled and noisy Fourier data. The underlying image is assumed to have some sparsity features, that is, some measurable features of the image have sparse representation. The reconstruction algorithm is typically designed to solve a convex optimization problem, which consists of a fidelity term penalized by one or more l 1 regularization terms. The Split Bregman Algorithm provides a fastmore » explicit solution for the case when TV is used for the l1l1 regularization terms. Due to its numerical efficiency, it has been widely adopted for a variety of applications. A well known drawback in using TV as an l 1 regularization term is that the reconstructed image will tend to default to a piecewise constant image. This issue has been addressed in several ways. Recently, the polynomial annihilation edge detection method was used to generate a higher order sparsifying transform, and was coined the “polynomial annihilation (PA) transform.” This paper adapts the Split Bregman Algorithm for the case when the PA transform is used as the l 1 regularization term. In so doing, we achieve a more accurate image reconstruction method from under-sampled and noisy Fourier data. Our new method compares favorably to the TV Split Bregman Algorithm, as well as to the popular TGV combined with shearlet approach.« less

  13. Computed inverse resonance imaging for magnetic susceptibility map reconstruction.

    PubMed

    Chen, Zikuan; Calhoun, Vince

    2012-01-01

    This article reports a computed inverse magnetic resonance imaging (CIMRI) model for reconstructing the magnetic susceptibility source from MRI data using a 2-step computational approach. The forward T2*-weighted MRI (T2*MRI) process is broken down into 2 steps: (1) from magnetic susceptibility source to field map establishment via magnetization in the main field and (2) from field map to MR image formation by intravoxel dephasing average. The proposed CIMRI model includes 2 inverse steps to reverse the T2*MRI procedure: field map calculation from MR-phase image and susceptibility source calculation from the field map. The inverse step from field map to susceptibility map is a 3-dimensional ill-posed deconvolution problem, which can be solved with 3 kinds of approaches: the Tikhonov-regularized matrix inverse, inverse filtering with a truncated filter, and total variation (TV) iteration. By numerical simulation, we validate the CIMRI model by comparing the reconstructed susceptibility maps for a predefined susceptibility source. Numerical simulations of CIMRI show that the split Bregman TV iteration solver can reconstruct the susceptibility map from an MR-phase image with high fidelity (spatial correlation ≈ 0.99). The split Bregman TV iteration solver includes noise reduction, edge preservation, and image energy conservation. For applications to brain susceptibility reconstruction, it is important to calibrate the TV iteration program by selecting suitable values of the regularization parameter. The proposed CIMRI model can reconstruct the magnetic susceptibility source of T2*MRI by 2 computational steps: calculating the field map from the phase image and reconstructing the susceptibility map from the field map. The crux of CIMRI lies in an ill-posed 3-dimensional deconvolution problem, which can be effectively solved by the split Bregman TV iteration algorithm.

  14. Computed inverse MRI for magnetic susceptibility map reconstruction

    PubMed Central

    Chen, Zikuan; Calhoun, Vince

    2015-01-01

    Objective This paper reports on a computed inverse magnetic resonance imaging (CIMRI) model for reconstructing the magnetic susceptibility source from MRI data using a two-step computational approach. Methods The forward T2*-weighted MRI (T2*MRI) process is decomposed into two steps: 1) from magnetic susceptibility source to fieldmap establishment via magnetization in a main field, and 2) from fieldmap to MR image formation by intravoxel dephasing average. The proposed CIMRI model includes two inverse steps to reverse the T2*MRI procedure: fieldmap calculation from MR phase image and susceptibility source calculation from the fieldmap. The inverse step from fieldmap to susceptibility map is a 3D ill-posed deconvolution problem, which can be solved by three kinds of approaches: Tikhonov-regularized matrix inverse, inverse filtering with a truncated filter, and total variation (TV) iteration. By numerical simulation, we validate the CIMRI model by comparing the reconstructed susceptibility maps for a predefined susceptibility source. Results Numerical simulations of CIMRI show that the split Bregman TV iteration solver can reconstruct the susceptibility map from a MR phase image with high fidelity (spatial correlation≈0.99). The split Bregman TV iteration solver includes noise reduction, edge preservation, and image energy conservation. For applications to brain susceptibility reconstruction, it is important to calibrate the TV iteration program by selecting suitable values of the regularization parameter. Conclusions The proposed CIMRI model can reconstruct the magnetic susceptibility source of T2*MRI by two computational steps: calculating the fieldmap from the phase image and reconstructing the susceptibility map from the fieldmap. The crux of CIMRI lies in an ill-posed 3D deconvolution problem, which can be effectively solved by the split Bregman TV iteration algorithm. PMID:22446372

  15. Nonsmooth, nonconvex regularizers applied to linear electromagnetic inverse problems

    NASA Astrophysics Data System (ADS)

    Hidalgo-Silva, H.; Gomez-Trevino, E.

    2017-12-01

    Tikhonov's regularization method is the standard technique applied to obtain models of the subsurface conductivity distribution from electric or electromagnetic measurements by solving UT (m) = | F (m) - d |2 + λ P(m). The second term correspond to the stabilizing functional, with P (m) = | ∇ m |2 the usual approach, and λ the regularization parameter. Due to the roughness penalizer inclusion, the model developed by Tikhonov's algorithm tends to smear discontinuities, a feature that may be undesirable. An important requirement for the regularizer is to allow the recovery of edges, and smooth the homogeneous parts. As is well known, Total Variation (TV) is now the standard approach to meet this requirement. Recently, Wang et.al. proved convergence for alternating direction method of multipliers in nonconvex, nonsmooth optimization. In this work we present a study of several algorithms for model recovering of Geosounding data based on Infimal Convolution, and also on hybrid, TV and second order TV and nonsmooth, nonconvex regularizers, observing their performance on synthetic and real data. The algorithms are based on Bregman iteration and Split Bregman method, and the geosounding method is the low-induction numbers magnetic dipoles. Non-smooth regularizers are considered using the Legendre-Fenchel transform.

  16. Variational method based on Retinex with double-norm hybrid constraints for uneven illumination correction

    NASA Astrophysics Data System (ADS)

    Li, Shuo; Wang, Hui; Wang, Liyong; Yu, Xiangzhou; Yang, Le

    2018-01-01

    The uneven illumination phenomenon reduces the quality of remote sensing image and causes interference in the subsequent processing and applications. A variational method based on Retinex with double-norm hybrid constraints for uneven illumination correction is proposed. The L1 norm and the L2 norm are adopted to constrain the textures and details of reflectance image and the smoothness of the illumination image, respectively. The problem of separating the illumination image from the reflectance image is transformed into the optimal solution of the variational model. In order to accelerate the solution, the split Bregman method is used to decompose the variational model into three subproblems, which are calculated by alternate iteration. Two groups of experiments are implemented on two synthetic images and three real remote sensing images. Compared with the variational Retinex method with single-norm constraint and the Mask method, the proposed method performs better in both visual evaluation and quantitative measurements. The proposed method can effectively eliminate the uneven illumination while maintaining the textures and details of the remote sensing image. Moreover, the proposed method using split Bregman method is more than 10 times faster than the method with the steepest descent method.

  17. Sparse magnetic resonance imaging reconstruction using the bregman iteration

    NASA Astrophysics Data System (ADS)

    Lee, Dong-Hoon; Hong, Cheol-Pyo; Lee, Man-Woo

    2013-01-01

    Magnetic resonance imaging (MRI) reconstruction needs many samples that are sequentially sampled by using phase encoding gradients in a MRI system. It is directly connected to the scan time for the MRI system and takes a long time. Therefore, many researchers have studied ways to reduce the scan time, especially, compressed sensing (CS), which is used for sparse images and reconstruction for fewer sampling datasets when the k-space is not fully sampled. Recently, an iterative technique based on the bregman method was developed for denoising. The bregman iteration method improves on total variation (TV) regularization by gradually recovering the fine-scale structures that are usually lost in TV regularization. In this study, we studied sparse sampling image reconstruction using the bregman iteration for a low-field MRI system to improve its temporal resolution and to validate its usefulness. The image was obtained with a 0.32 T MRI scanner (Magfinder II, SCIMEDIX, Korea) with a phantom and an in-vivo human brain in a head coil. We applied random k-space sampling, and we determined the sampling ratios by using half the fully sampled k-space. The bregman iteration was used to generate the final images based on the reduced data. We also calculated the root-mean-square-error (RMSE) values from error images that were obtained using various numbers of bregman iterations. Our reconstructed images using the bregman iteration for sparse sampling images showed good results compared with the original images. Moreover, the RMSE values showed that the sparse reconstructed phantom and the human images converged to the original images. We confirmed the feasibility of sparse sampling image reconstruction methods using the bregman iteration with a low-field MRI system and obtained good results. Although our results used half the sampling ratio, this method will be helpful in increasing the temporal resolution at low-field MRI systems.

  18. Efficient operator splitting algorithm for joint sparsity-regularized SPIRiT-based parallel MR imaging reconstruction.

    PubMed

    Duan, Jizhong; Liu, Yu; Jing, Peiguang

    2018-02-01

    Self-consistent parallel imaging (SPIRiT) is an auto-calibrating model for the reconstruction of parallel magnetic resonance imaging, which can be formulated as a regularized SPIRiT problem. The Projection Over Convex Sets (POCS) method was used to solve the formulated regularized SPIRiT problem. However, the quality of the reconstructed image still needs to be improved. Though methods such as NonLinear Conjugate Gradients (NLCG) can achieve higher spatial resolution, these methods always demand very complex computation and converge slowly. In this paper, we propose a new algorithm to solve the formulated Cartesian SPIRiT problem with the JTV and JL1 regularization terms. The proposed algorithm uses the operator splitting (OS) technique to decompose the problem into a gradient problem and a denoising problem with two regularization terms, which is solved by our proposed split Bregman based denoising algorithm, and adopts the Barzilai and Borwein method to update step size. Simulation experiments on two in vivo data sets demonstrate that the proposed algorithm is 1.3 times faster than ADMM for datasets with 8 channels. Especially, our proposal is 2 times faster than ADMM for the dataset with 32 channels. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Mathematical filtering minimizes metallic halation of titanium implants in MicroCT images.

    PubMed

    Ha, Jee; Osher, Stanley J; Nishimura, Ichiro

    2013-01-01

    Microcomputed tomography (MicroCT) images containing titanium implant suffer from x-rays scattering, artifact and the implant surface is critically affected by metallic halation. To improve the metallic halation artifact, a nonlinear Total Variation denoising algorithm such as Split Bregman algorithm was applied to the digital data set of MicroCT images. This study demonstrated that the use of a mathematical filter could successfully reduce metallic halation, facilitating the osseointegration evaluation at the bone implant interface in the reconstructed images.

  20. Regularization Reconstruction Method for Imaging Problems in Electrical Capacitance Tomography

    NASA Astrophysics Data System (ADS)

    Chu, Pan; Lei, Jing

    2017-11-01

    The electrical capacitance tomography (ECT) is deemed to be a powerful visualization measurement technique for the parametric measurement in a multiphase flow system. The inversion task in the ECT technology is an ill-posed inverse problem, and seeking for an efficient numerical method to improve the precision of the reconstruction images is important for practical measurements. By the introduction of the Tikhonov regularization (TR) methodology, in this paper a loss function that emphasizes the robustness of the estimation and the low rank property of the imaging targets is put forward to convert the solution of the inverse problem in the ECT reconstruction task into a minimization problem. Inspired by the split Bregman (SB) algorithm, an iteration scheme is developed for solving the proposed loss function. Numerical experiment results validate that the proposed inversion method not only reconstructs the fine structures of the imaging targets, but also improves the robustness.

  1. Universal portfolios generated by the Bregman divergence

    NASA Astrophysics Data System (ADS)

    Tan, Choon Peng; Kuang, Kee Seng

    2017-04-01

    The Bregman divergence of two probability vectors is a stronger form of the f-divergence introduced by Csiszar. Two versions of the Bregman universal portfolio are presented by exploiting the mean-value theorem. The explicit form of the Bregman universal portfolio generated by a function of a convex polynomial is derived and studied empirically. This portfolio can be regarded as another generalized of the well-known Helmbold portfolio. By running the portfolios on selected stock-price data sets from the local stock exchange, it is shown that it is possible to increase the wealth of the investor by using the portfolios in investment.

  2. 3D and 4D magnetic susceptibility tomography based on complex MR images

    DOEpatents

    Chen, Zikuan; Calhoun, Vince D

    2014-11-11

    Magnetic susceptibility is the physical property for T2*-weighted magnetic resonance imaging (T2*MRI). The invention relates to methods for reconstructing an internal distribution (3D map) of magnetic susceptibility values, .chi. (x,y,z), of an object, from 3D T2*MRI phase images, by using Computed Inverse Magnetic Resonance Imaging (CIMRI) tomography. The CIMRI technique solves the inverse problem of the 3D convolution by executing a 3D Total Variation (TV) regularized iterative convolution scheme, using a split Bregman iteration algorithm. The reconstruction of .chi. (x,y,z) can be designed for low-pass, band-pass, and high-pass features by using a convolution kernel that is modified from the standard dipole kernel. Multiple reconstructions can be implemented in parallel, and averaging the reconstructions can suppress noise. 4D dynamic magnetic susceptibility tomography can be implemented by reconstructing a 3D susceptibility volume from a 3D phase volume by performing 3D CIMRI magnetic susceptibility tomography at each snapshot time.

  3. Spectral CT Reconstruction with Image Sparsity and Spectral Mean

    PubMed Central

    Zhang, Yi; Xi, Yan; Yang, Qingsong; Cong, Wenxiang; Zhou, Jiliu

    2017-01-01

    Photon-counting detectors can acquire x-ray intensity data in different energy bins. The signal to noise ratio of resultant raw data in each energy bin is generally low due to the narrow bin width and quantum noise. To address this problem, here we propose an image reconstruction approach for spectral CT to simultaneously reconstructs x-ray attenuation coefficients in all the energy bins. Because the measured spectral data are highly correlated among the x-ray energy bins, the intra-image sparsity and inter-image similarity are important prior acknowledge for image reconstruction. Inspired by this observation, the total variation (TV) and spectral mean (SM) measures are combined to improve the quality of reconstructed images. For this purpose, a linear mapping function is used to minimalize image differences between energy bins. The split Bregman technique is applied to perform image reconstruction. Our numerical and experimental results show that the proposed algorithms outperform competing iterative algorithms in this context. PMID:29034267

  4. Functional Bregman Divergence and Bayesian Estimation of Distributions (Preprint)

    DTIC Science & Technology

    2008-01-01

    shows that if the set of possible minimizers A includes EPF [F ], then g∗ = EPF [F ] minimizes the expectation of any Bregman divergence. Note the theorem...probability distribution PF defined over the set M. Let A be a set of functions that includes EPF [F ] if it exists. Suppose the function g∗ minimizes...the expected Bregman divergence between the random function F and any function g ∈ A such that g∗ = arg inf g∈A EPF [dφ(F, g)]. Then, if g∗ exists

  5. A second order derivative scheme based on Bregman algorithm class

    NASA Astrophysics Data System (ADS)

    Campagna, Rosanna; Crisci, Serena; Cuomo, Salvatore; Galletti, Ardelio; Marcellino, Livia

    2016-10-01

    The algorithms based on the Bregman iterative regularization are known for efficiently solving convex constraint optimization problems. In this paper, we introduce a second order derivative scheme for the class of Bregman algorithms. Its properties of convergence and stability are investigated by means of numerical evidences. Moreover, we apply the proposed scheme to an isotropic Total Variation (TV) problem arising out of the Magnetic Resonance Image (MRI) denoising. Experimental results confirm that our algorithm has good performance in terms of denoising quality, effectiveness and robustness.

  6. Computerized tomography with total variation and with shearlets

    NASA Astrophysics Data System (ADS)

    Garduño, Edgar; Herman, Gabor T.

    2017-04-01

    To reduce the x-ray dose in computerized tomography (CT), many constrained optimization approaches have been proposed aiming at minimizing a regularizing function that measures a lack of consistency with some prior knowledge about the object that is being imaged, subject to a (predetermined) level of consistency with the detected attenuation of x-rays. One commonly investigated regularizing function is total variation (TV), while other publications advocate the use of some type of multiscale geometric transform in the definition of the regularizing function, a particular recent choice for this is the shearlet transform. Proponents of the shearlet transform in the regularizing function claim that the reconstructions so obtained are better than those produced using TV for texture preservation (but may be worse for noise reduction). In this paper we report results related to this claim. In our reported experiments using simulated CT data collection of the head, reconstructions whose shearlet transform has a small ℓ 1-norm are not more efficacious than reconstructions that have a small TV value. Our experiments for making such comparisons use the recently-developed superiorization methodology for both regularizing functions. Superiorization is an automated procedure for turning an iterative algorithm for producing images that satisfy a primary criterion (such as consistency with the observed measurements) into its superiorized version that will produce results that, according to the primary criterion are as good as those produced by the original algorithm, but in addition are superior to them according to a secondary (regularizing) criterion. The method presented for superiorization involving the ℓ 1-norm of the shearlet transform is novel and is quite general: It can be used for any regularizing function that is defined as the ℓ 1-norm of a transform specified by the application of a matrix. Because in the previous literature the split Bregman algorithm is used for similar purposes, a section is included comparing the results of the superiorization algorithm with the split Bregman algorithm.

  7. Deconvolution of post-adaptive optics images of faint circumstellar environments by means of the inexact Bregman procedure

    NASA Astrophysics Data System (ADS)

    Benfenati, A.; La Camera, A.; Carbillet, M.

    2016-02-01

    Aims: High-dynamic range images of astrophysical objects present some difficulties in their restoration because of the presence of very bright point-wise sources surrounded by faint and smooth structures. We propose a method that enables the restoration of this kind of images by taking these kinds of sources into account and, at the same time, improving the contrast enhancement in the final image. Moreover, the proposed approach can help to detect the position of the bright sources. Methods: The classical variational scheme in the presence of Poisson noise aims to find the minimum of a functional compound of the generalized Kullback-Leibler function and a regularization functional: the latter function is employed to preserve some characteristic in the restored image. The inexact Bregman procedure substitutes the regularization function with its inexact Bregman distance. This proposed scheme allows us to take under control the level of inexactness arising in the computed solution and permits us to employ an overestimation of the regularization parameter (which balances the trade-off between the Kullback-Leibler and the Bregman distance). This aspect is fundamental, since the estimation of this kind of parameter is very difficult in the presence of Poisson noise. Results: The inexact Bregman procedure is tested on a bright unresolved binary star with a faint circumstellar environment. When the sources' position is exactly known, this scheme provides us with very satisfactory results. In case of inexact knowledge of the sources' position, it can in addition give some useful information on the true positions. Finally, the inexact Bregman scheme can be also used when information about the binary star's position concerns a connected region instead of isolated pixels.

  8. 3D first-arrival traveltime tomography with modified total variation regularization

    NASA Astrophysics Data System (ADS)

    Jiang, Wenbin; Zhang, Jie

    2018-02-01

    Three-dimensional (3D) seismic surveys have become a major tool in the exploration and exploitation of hydrocarbons. 3D seismic first-arrival traveltime tomography is a robust method for near-surface velocity estimation. A common approach for stabilizing the ill-posed inverse problem is to apply Tikhonov regularization to the inversion. However, the Tikhonov regularization method recovers smooth local structures while blurring the sharp features in the model solution. We present a 3D first-arrival traveltime tomography method with modified total variation (MTV) regularization to preserve sharp velocity contrasts and improve the accuracy of velocity inversion. To solve the minimization problem of the new traveltime tomography method, we decouple the original optimization problem into two following subproblems: a standard traveltime tomography problem with the traditional Tikhonov regularization and a L2 total variation problem. We apply the conjugate gradient method and split-Bregman iterative method to solve these two subproblems, respectively. Our synthetic examples show that the new method produces higher resolution models than the conventional traveltime tomography with Tikhonov regularization. We apply the technique to field data. The stacking section shows significant improvements with static corrections from the MTV traveltime tomography.

  9. An Efficient Augmented Lagrangian Method for Statistical X-Ray CT Image Reconstruction.

    PubMed

    Li, Jiaojiao; Niu, Shanzhou; Huang, Jing; Bian, Zhaoying; Feng, Qianjin; Yu, Gaohang; Liang, Zhengrong; Chen, Wufan; Ma, Jianhua

    2015-01-01

    Statistical iterative reconstruction (SIR) for X-ray computed tomography (CT) under the penalized weighted least-squares criteria can yield significant gains over conventional analytical reconstruction from the noisy measurement. However, due to the nonlinear expression of the objective function, most exiting algorithms related to the SIR unavoidably suffer from heavy computation load and slow convergence rate, especially when an edge-preserving or sparsity-based penalty or regularization is incorporated. In this work, to address abovementioned issues of the general algorithms related to the SIR, we propose an adaptive nonmonotone alternating direction algorithm in the framework of augmented Lagrangian multiplier method, which is termed as "ALM-ANAD". The algorithm effectively combines an alternating direction technique with an adaptive nonmonotone line search to minimize the augmented Lagrangian function at each iteration. To evaluate the present ALM-ANAD algorithm, both qualitative and quantitative studies were conducted by using digital and physical phantoms. Experimental results show that the present ALM-ANAD algorithm can achieve noticeable gains over the classical nonlinear conjugate gradient algorithm and state-of-the-art split Bregman algorithm in terms of noise reduction, contrast-to-noise ratio, convergence rate, and universal quality index metrics.

  10. Convex foundations for generalized MaxEnt models

    NASA Astrophysics Data System (ADS)

    Frongillo, Rafael; Reid, Mark D.

    2014-12-01

    We present an approach to maximum entropy models that highlights the convex geometry and duality of generalized exponential families (GEFs) and their connection to Bregman divergences. Using our framework, we are able to resolve a puzzling aspect of the bijection of Banerjee and coauthors between classical exponential families and what they call regular Bregman divergences. Their regularity condition rules out all but Bregman divergences generated from log-convex generators. We recover their bijection and show that a much broader class of divergences correspond to GEFs via two key observations: 1) Like classical exponential families, GEFs have a "cumulant" C whose subdifferential contains the mean: Eo˜pθ[φ(o)]∈∂C(θ) ; 2) Generalized relative entropy is a C-Bregman divergence between parameters: DF(pθ,pθ')= D C(θ,θ') , where DF becomes the KL divergence for F = -H. We also show that every incomplete market with cost function C can be expressed as a complete market, where the prices are constrained to be a GEF with cumulant C. This provides an entirely new interpretation of prediction markets, relating their design back to the principle of maximum entropy.

  11. Target detection in GPR data using joint low-rank and sparsity constraints

    NASA Astrophysics Data System (ADS)

    Bouzerdoum, Abdesselam; Tivive, Fok Hing Chi; Abeynayake, Canicious

    2016-05-01

    In ground penetrating radars, background clutter, which comprises the signals backscattered from the rough, uneven ground surface and the background noise, impairs the visualization of buried objects and subsurface inspections. In this paper, a clutter mitigation method is proposed for target detection. The removal of background clutter is formulated as a constrained optimization problem to obtain a low-rank matrix and a sparse matrix. The low-rank matrix captures the ground surface reflections and the background noise, whereas the sparse matrix contains the target reflections. An optimization method based on split-Bregman algorithm is developed to estimate these two matrices from the input GPR data. Evaluated on real radar data, the proposed method achieves promising results in removing the background clutter and enhancing the target signature.

  12. Total variation-based neutron computed tomography

    NASA Astrophysics Data System (ADS)

    Barnard, Richard C.; Bilheux, Hassina; Toops, Todd; Nafziger, Eric; Finney, Charles; Splitter, Derek; Archibald, Rick

    2018-05-01

    We perform the neutron computed tomography reconstruction problem via an inverse problem formulation with a total variation penalty. In the case of highly under-resolved angular measurements, the total variation penalty suppresses high-frequency artifacts which appear in filtered back projections. In order to efficiently compute solutions for this problem, we implement a variation of the split Bregman algorithm; due to the error-forgetting nature of the algorithm, the computational cost of updating can be significantly reduced via very inexact approximate linear solvers. We present the effectiveness of the algorithm in the significantly low-angular sampling case using synthetic test problems as well as data obtained from a high flux neutron source. The algorithm removes artifacts and can even roughly capture small features when an extremely low number of angles are used.

  13. Tchebichef moment based restoration of Gaussian blurred images.

    PubMed

    Kumar, Ahlad; Paramesran, Raveendran; Lim, Chern-Loon; Dass, Sarat C

    2016-11-10

    With the knowledge of how edges vary in the presence of a Gaussian blur, a method that uses low-order Tchebichef moments is proposed to estimate the blur parameters: sigma (σ) and size (w). The difference between the Tchebichef moments of the original and the reblurred images is used as feature vectors to train an extreme learning machine for estimating the blur parameters (σ,w). The effectiveness of the proposed method to estimate the blur parameters is examined using cross-database validation. The estimated blur parameters from the proposed method are used in the split Bregman-based image restoration algorithm. A comparative analysis of the proposed method with three existing methods using all the images from the LIVE database is carried out. The results show that the proposed method in most of the cases performs better than the three existing methods in terms of the visual quality evaluated using the structural similarity index.

  14. Total Bregman Divergence and its Applications to Shape Retrieval.

    PubMed

    Liu, Meizhu; Vemuri, Baba C; Amari, Shun-Ichi; Nielsen, Frank

    2010-01-01

    Shape database search is ubiquitous in the world of biometric systems, CAD systems etc. Shape data in these domains is experiencing an explosive growth and usually requires search of whole shape databases to retrieve the best matches with accuracy and efficiency for a variety of tasks. In this paper, we present a novel divergence measure between any two given points in [Formula: see text] or two distribution functions. This divergence measures the orthogonal distance between the tangent to the convex function (used in the definition of the divergence) at one of its input arguments and its second argument. This is in contrast to the ordinate distance taken in the usual definition of the Bregman class of divergences [4]. We use this orthogonal distance to redefine the Bregman class of divergences and develop a new theory for estimating the center of a set of vectors as well as probability distribution functions. The new class of divergences are dubbed the total Bregman divergence (TBD). We present the l 1 -norm based TBD center that is dubbed the t-center which is then used as a cluster center of a class of shapes The t-center is weighted mean and this weight is small for noise and outliers. We present a shape retrieval scheme using TBD and the t-center for representing the classes of shapes from the MPEG-7 database and compare the results with other state-of-the-art methods in literature.

  15. Generalized Bregman distances and convergence rates for non-convex regularization methods

    NASA Astrophysics Data System (ADS)

    Grasmair, Markus

    2010-11-01

    We generalize the notion of Bregman distance using concepts from abstract convexity in order to derive convergence rates for Tikhonov regularization with non-convex regularization terms. In particular, we study the non-convex regularization of linear operator equations on Hilbert spaces, showing that the conditions required for the application of the convergence rates results are strongly related to the standard range conditions from the convex case. Moreover, we consider the setting of sparse regularization, where we show that a rate of order δ1/p holds, if the regularization term has a slightly faster growth at zero than |t|p.

  16. Nonlocal Total-Variation-Based Speckle Filtering for Ultrasound Images.

    PubMed

    Wen, Tiexiang; Gu, Jia; Li, Ling; Qin, Wenjian; Wang, Lei; Xie, Yaoqin

    2016-07-01

    Ultrasound is one of the most important medical imaging modalities for its real-time and portable imaging advantages. However, the contrast resolution and important details are degraded by the speckle in ultrasound images. Many speckle filtering methods have been developed, but they are suffered from several limitations, difficult to reach a balance between speckle reduction and edge preservation. In this paper, an adaptation of the nonlocal total variation (NLTV) filter is proposed for speckle reduction in ultrasound images. The speckle is modeled via a signal-dependent noise distribution for the log-compressed ultrasound images. Instead of the Euclidian distance, the statistical Pearson distance is introduced in this study for the similarity calculation between image patches via the Bayesian framework. And the Split-Bregman fast algorithm is used to solve the adapted NLTV despeckling functional. Experimental results on synthetic and clinical ultrasound images and comparisons with some classical and recent algorithms are used to demonstrate its improvements in both speckle noise reduction and tissue boundary preservation for ultrasound images. © The Author(s) 2015.

  17. Low-illumination image denoising method for wide-area search of nighttime sea surface

    NASA Astrophysics Data System (ADS)

    Song, Ming-zhu; Qu, Hong-song; Zhang, Gui-xiang; Tao, Shu-ping; Jin, Guang

    2018-05-01

    In order to suppress complex mixing noise in low-illumination images for wide-area search of nighttime sea surface, a model based on total variation (TV) and split Bregman is proposed in this paper. A fidelity term based on L1 norm and a fidelity term based on L2 norm are designed considering the difference between various noise types, and the regularization mixed first-order TV and second-order TV are designed to balance the influence of details information such as texture and edge for sea surface image. The final detection result is obtained by using the high-frequency component solved from L1 norm and the low-frequency component solved from L2 norm through wavelet transform. The experimental results show that the proposed denoising model has perfect denoising performance for artificially degraded and low-illumination images, and the result of image quality assessment index for the denoising image is superior to that of the contrastive models.

  18. New second order Mumford-Shah model based on Γ-convergence approximation for image processing

    NASA Astrophysics Data System (ADS)

    Duan, Jinming; Lu, Wenqi; Pan, Zhenkuan; Bai, Li

    2016-05-01

    In this paper, a second order variational model named the Mumford-Shah total generalized variation (MSTGV) is proposed for simultaneously image denoising and segmentation, which combines the original Γ-convergence approximated Mumford-Shah model with the second order total generalized variation (TGV). For image denoising, the proposed MSTGV can eliminate both the staircase artefact associated with the first order total variation and the edge blurring effect associated with the quadratic H1 regularization or the second order bounded Hessian regularization. For image segmentation, the MSTGV can obtain clear and continuous boundaries of objects in the image. To improve computational efficiency, the implementation of the MSTGV does not directly solve its high order nonlinear partial differential equations and instead exploits the efficient split Bregman algorithm. The algorithm benefits from the fast Fourier transform, analytical generalized soft thresholding equation, and Gauss-Seidel iteration. Extensive experiments are conducted to demonstrate the effectiveness and efficiency of the proposed model.

  19. Speckle reduction in optical coherence tomography using two-step iteration method (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Wang, Xianghong; Liu, Xinyu; Wang, Nanshuo; Yu, Xiaojun; Bo, En; Chen, Si; Liu, Linbo

    2017-02-01

    Optical coherence tomography (OCT) provides high resolution and cross-sectional images of biological tissue and is widely used for diagnosis of ocular diseases. However, OCT images suffer from speckle noise, which typically considered as multiplicative noise in nature, reducing the image resolution and contrast. In this study, we propose a two-step iteration (TSI) method to suppress those noises. We first utilize augmented Lagrange method to recover a low-rank OCT image and remove additive Gaussian noise, and then employ the simple and efficient split Bregman method to solve the Total-Variation Denoising model. We validated such proposed method using images of swine, rabbit and human retina. Results demonstrate that our TSI method outperforms the other popular methods in achieving higher peak signal-to-noise ratio (PSNR) and structure similarity (SSIM) while preserving important structural details, such as tiny capillaries and thin layers in retinal OCT images. In addition, the results of our TSI method show clearer boundaries and maintains high image contrast, which facilitates better image interpretations and analyses.

  20. Unveiling the development of intracranial injury using dynamic brain EIT: an evaluation of current reconstruction algorithms.

    PubMed

    Li, Haoting; Chen, Rongqing; Xu, Canhua; Liu, Benyuan; Tang, Mengxing; Yang, Lin; Dong, Xiuzhen; Fu, Feng

    2017-08-21

    Dynamic brain electrical impedance tomography (EIT) is a promising technique for continuously monitoring the development of cerebral injury. While there are many reconstruction algorithms available for brain EIT, there is still a lack of study to compare their performance in the context of dynamic brain monitoring. To address this problem, we develop a framework for evaluating different current algorithms with their ability to correctly identify small intracranial conductivity changes. Firstly, a simulation 3D head phantom with realistic layered structure and impedance distribution is developed. Next several reconstructing algorithms, such as back projection (BP), damped least-square (DLS), Bayesian, split Bregman (SB) and GREIT are introduced. We investigate their temporal response, noise performance, location and shape error with respect to different noise levels on the simulation phantom. The results show that the SB algorithm demonstrates superior performance in reducing image error. To further improve the location accuracy, we optimize SB by incorporating the brain structure-based conductivity distribution priors, in which differences of the conductivities between different brain tissues and the inhomogeneous conductivity distribution of the skull are considered. We compare this novel algorithm (called SB-IBCD) with SB and DLS using anatomically correct head shaped phantoms with spatial varying skull conductivity. Main results and Significance: The results showed that SB-IBCD is the most effective in unveiling small intracranial conductivity changes, where it can reduce the image error by an average of 30.0% compared to DLS.

  1. Hybrid spectral CT reconstruction

    PubMed Central

    Clark, Darin P.

    2017-01-01

    Current photon counting x-ray detector (PCD) technology faces limitations associated with spectral fidelity and photon starvation. One strategy for addressing these limitations is to supplement PCD data with high-resolution, low-noise data acquired with an energy-integrating detector (EID). In this work, we propose an iterative, hybrid reconstruction technique which combines the spectral properties of PCD data with the resolution and signal-to-noise characteristics of EID data. Our hybrid reconstruction technique is based on an algebraic model of data fidelity which substitutes the EID data into the data fidelity term associated with the PCD reconstruction, resulting in a joint reconstruction problem. Within the split Bregman framework, these data fidelity constraints are minimized subject to additional constraints on spectral rank and on joint intensity-gradient sparsity measured between the reconstructions of the EID and PCD data. Following a derivation of the proposed technique, we apply it to the reconstruction of a digital phantom which contains realistic concentrations of iodine, barium, and calcium encountered in small-animal micro-CT. The results of this experiment suggest reliable separation and detection of iodine at concentrations ≥ 5 mg/ml and barium at concentrations ≥ 10 mg/ml in 2-mm features for EID and PCD data reconstructed with inherent spatial resolutions of 176 μm and 254 μm, respectively (point spread function, FWHM). Furthermore, hybrid reconstruction is demonstrated to enhance spatial resolution within material decomposition results and to improve low-contrast detectability by as much as 2.6 times relative to reconstruction with PCD data only. The parameters of the simulation experiment are based on an in vivo micro-CT experiment conducted in a mouse model of soft-tissue sarcoma. Material decomposition results produced from this in vivo data demonstrate the feasibility of distinguishing two K-edge contrast agents with a spectral separation on the order of the energy resolution of the PCD hardware. PMID:28683124

  2. Convex composite wavelet frame and total variation-based image deblurring using nonconvex penalty functions

    NASA Astrophysics Data System (ADS)

    Shen, Zhengwei; Cheng, Lishuang

    2017-09-01

    Total variation (TV)-based image deblurring method can bring on staircase artifacts in the homogenous region of the latent images recovered from the degraded images while a wavelet/frame-based image deblurring method will lead to spurious noise spikes and pseudo-Gibbs artifacts in the vicinity of discontinuities of the latent images. To suppress these artifacts efficiently, we propose a nonconvex composite wavelet/frame and TV-based image deblurring model. In this model, the wavelet/frame and the TV-based methods may complement each other, which are verified by theoretical analysis and experimental results. To further improve the quality of the latent images, nonconvex penalty function is used to be the regularization terms of the model, which may induce a stronger sparse solution and will more accurately estimate the relative large gradient or wavelet/frame coefficients of the latent images. In addition, by choosing a suitable parameter to the nonconvex penalty function, the subproblem that splits by the alternative direction method of multipliers algorithm from the proposed model can be guaranteed to be a convex optimization problem; hence, each subproblem can converge to a global optimum. The mean doubly augmented Lagrangian and the isotropic split Bregman algorithms are used to solve these convex subproblems where the designed proximal operator is used to reduce the computational complexity of the algorithms. Extensive numerical experiments indicate that the proposed model and algorithms are comparable to other state-of-the-art model and methods.

  3. Compressed sensing for rapid late gadolinium enhanced imaging of the left atrium: A preliminary study.

    PubMed

    Kamesh Iyer, Srikant; Tasdizen, Tolga; Burgon, Nathan; Kholmovski, Eugene; Marrouche, Nassir; Adluru, Ganesh; DiBella, Edward

    2016-09-01

    Current late gadolinium enhancement (LGE) imaging of left atrial (LA) scar or fibrosis is relatively slow and requires 5-15min to acquire an undersampled (R=1.7) 3D navigated dataset. The GeneRalized Autocalibrating Partially Parallel Acquisitions (GRAPPA) based parallel imaging method is the current clinical standard for accelerating 3D LGE imaging of the LA and permits an acceleration factor ~R=1.7. Two compressed sensing (CS) methods have been developed to achieve higher acceleration factors: a patch based collaborative filtering technique tested with acceleration factor R~3, and a technique that uses a 3D radial stack-of-stars acquisition pattern (R~1.8) with a 3D total variation constraint. The long reconstruction time of these CS methods makes them unwieldy to use, especially the patch based collaborative filtering technique. In addition, the effect of CS techniques on the quantification of percentage of scar/fibrosis is not known. We sought to develop a practical compressed sensing method for imaging the LA at high acceleration factors. In order to develop a clinically viable method with short reconstruction time, a Split Bregman (SB) reconstruction method with 3D total variation (TV) constraints was developed and implemented. The method was tested on 8 atrial fibrillation patients (4 pre-ablation and 4 post-ablation datasets). Blur metric, normalized mean squared error and peak signal to noise ratio were used as metrics to analyze the quality of the reconstructed images, Quantification of the extent of LGE was performed on the undersampled images and compared with the fully sampled images. Quantification of scar from post-ablation datasets and quantification of fibrosis from pre-ablation datasets showed that acceleration factors up to R~3.5 gave good 3D LGE images of the LA wall, using a 3D TV constraint and constrained SB methods. This corresponds to reducing the scan time by half, compared to currently used GRAPPA methods. Reconstruction of 3D LGE images using the SB method was over 20 times faster than standard gradient descent methods. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. WE-G-207-04: Non-Local Total-Variation (NLTV) Combined with Reweighted L1-Norm for Compressed Sensing Based CT Reconstruction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, H; Chen, J; Pouliot, J

    2015-06-15

    Purpose: Compressed sensing (CS) has been used for CT (4DCT/CBCT) reconstruction with few projections to reduce dose of radiation. Total-variation (TV) in L1-minimization (min.) with local information is the prevalent technique in CS, while it can be prone to noise. To address the problem, this work proposes to apply a new image processing technique, called non-local TV (NLTV), to CS based CT reconstruction, and incorporate reweighted L1-norm into it for more precise reconstruction. Methods: TV minimizes intensity variations by considering two local neighboring voxels, which can be prone to noise, possibly damaging the reconstructed CT image. NLTV, contrarily, utilizes moremore » global information by computing a weight function of current voxel relative to surrounding search area. In fact, it might be challenging to obtain an optimal solution due to difficulty in defining the weight function with appropriate parameters. Introducing reweighted L1-min., designed for approximation to ideal L0-min., can reduce the dependence on defining the weight function, therefore improving accuracy of the solution. This work implemented the NLTV combined with reweighted L1-min. by Split Bregman Iterative method. For evaluation, a noisy digital phantom and a pelvic CT images are employed to compare the quality of images reconstructed by TV, NLTV and reweighted NLTV. Results: In both cases, conventional and reweighted NLTV outperform TV min. in signal-to-noise ratio (SNR) and root-mean squared errors of the reconstructed images. Relative to conventional NLTV, NLTV with reweighted L1-norm was able to slightly improve SNR, while greatly increasing the contrast between tissues due to additional iterative reweighting process. Conclusion: NLTV min. can provide more precise compressed sensing based CT image reconstruction by incorporating the reweighted L1-norm, while maintaining greater robustness to the noise effect than TV min.« less

  5. Infrared Submillimeter and Radio Astronomy Research and Analysis Program

    NASA Technical Reports Server (NTRS)

    Traub, Wesley A.

    2000-01-01

    This program entitled "Infrared Submillimeter and Radio Astronomy Research and Analysis Program" with NASA-Ames Research Center (ARC) was proposed by the Smithsonian Astrophysical Observatory (SAO) to cover three years. Due to funding constraints only the first year installment of $18,436 was funded, but this funding was spread out over two years to try to maximize the benefit to the program. During the tenure of this contact, the investigators at the SAO, Drs. Wesley A. Traub and Nathaniel P. Carleton, worked with the investigators at ARC, Drs. Jesse Bregman and Fred Wittebom, on the following three main areas: 1. Rapid scanning SAO and ARC collaborated on purchasing and constructing a Rapid Scan Platform for the delay arm of the Infrared-Optical Telescope Array (IOTA) interferometer on Mt. Hopkins, Arizona. The Rapid Scan Platform was tested and improved by the addition of stiffening plates which eliminated a very small but noticeable bending of the metal platform at the micro-meter level. 2. Star tracking Bregman and Wittebom conducted a study of the IOTA CCD-based star tracker system, by constructing a device to simulate star motion having a specified frequency and amplitude of motion, and by examining the response of the tracker to this simulated star input. 3. Fringe tracking. ARC, and in particular Dr. Robert Mah, developed a fringe-packet tracking algorithm, based on data that Bregman and Witteborn obtained on IOTA. The algorithm was tested in the laboratory at ARC, and found to work well for both strong and weak fringes.

  6. SU-C-207-05: A Comparative Study of Noise-Reduction Algorithms for Low-Dose Cone-Beam Computed Tomography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mukherjee, S; Yao, W

    2015-06-15

    Purpose: To study different noise-reduction algorithms and to improve the image quality of low dose cone beam CT for patient positioning in radiation therapy. Methods: In low-dose cone-beam CT, the reconstructed image is contaminated with excessive quantum noise. In this study, three well-developed noise reduction algorithms namely, a) penalized weighted least square (PWLS) method, b) split-Bregman total variation (TV) method, and c) compressed sensing (CS) method were studied and applied to the images of a computer–simulated “Shepp-Logan” phantom and a physical CATPHAN phantom. Up to 20% additive Gaussian noise was added to the Shepp-Logan phantom. The CATPHAN phantom was scannedmore » by a Varian OBI system with 100 kVp, 4 ms and 20 mA. For comparing the performance of these algorithms, peak signal-to-noise ratio (PSNR) of the denoised images was computed. Results: The algorithms were shown to have the potential in reducing the noise level for low-dose CBCT images. For Shepp-Logan phantom, an improvement of PSNR of 2 dB, 3.1 dB and 4 dB was observed using PWLS, TV and CS respectively, while for CATPHAN, the improvement was 1.2 dB, 1.8 dB and 2.1 dB, respectively. Conclusion: Penalized weighted least square, total variation and compressed sensing methods were studied and compared for reducing the noise on a simulated phantom and a physical phantom scanned by low-dose CBCT. The techniques have shown promising results for noise reduction in terms of PSNR improvement. However, reducing the noise without compromising the smoothness and resolution of the image needs more extensive research.« less

  7. Electrical Capacitance Tomography Measurement of the Migration of Ice Frontal Surface in Freezing Soil

    NASA Astrophysics Data System (ADS)

    Liu, J.; Suo, X. M.; Zhou, S. S.; Meng, S. Q.; Chen, S. S.; Mu, H. P.

    2016-12-01

    The tracking of the migration of ice frontal surface is crucial for the understanding of the underlying physical mechanisms in freezing soil. Owing to the distinct advantages, including non-invasive sensing, high safety, low cost and high data acquisition speed, the electrical capacitance tomography (ECT) is considered to be a promising visualization measurement method. In this paper, the ECT method is used to visualize the migration of ice frontal surface in freezing soil. With the main motivation of the improvement of imaging quality, a loss function with multiple regularizers that incorporate the prior formation related to the imaging objects is proposed to cast the ECT image reconstruction task into an optimization problem. An iteration scheme that integrates the superiority of the split Bregman iteration (SBI) method is developed for searching for the optimal solution of the proposed loss function. An unclosed electrodes sensor is designed for satisfying the requirements of practical measurements. An experimental system of one dimensional freezing in frozen soil is constructed, and the ice frontal surface migration in the freezing process of the wet soil sample containing five percent of moisture is measured. The visualization measurement results validate the feasibility and effectiveness of the ECT visualization method

  8. Low-dose dynamic myocardial perfusion CT image reconstruction using pre-contrast normal-dose CT scan induced structure tensor total variation regularization

    NASA Astrophysics Data System (ADS)

    Gong, Changfei; Han, Ce; Gan, Guanghui; Deng, Zhenxiang; Zhou, Yongqiang; Yi, Jinling; Zheng, Xiaomin; Xie, Congying; Jin, Xiance

    2017-04-01

    Dynamic myocardial perfusion CT (DMP-CT) imaging provides quantitative functional information for diagnosis and risk stratification of coronary artery disease by calculating myocardial perfusion hemodynamic parameter (MPHP) maps. However, the level of radiation delivered by dynamic sequential scan protocol can be potentially high. The purpose of this work is to develop a pre-contrast normal-dose scan induced structure tensor total variation regularization based on the penalized weighted least-squares (PWLS) criteria to improve the image quality of DMP-CT with a low-mAs CT acquisition. For simplicity, the present approach was termed as ‘PWLS-ndiSTV’. Specifically, the ndiSTV regularization takes into account the spatial-temporal structure information of DMP-CT data and further exploits the higher order derivatives of the objective images to enhance denoising performance. Subsequently, an effective optimization algorithm based on the split-Bregman approach was adopted to minimize the associative objective function. Evaluations with modified dynamic XCAT phantom and preclinical porcine datasets have demonstrated that the proposed PWLS-ndiSTV approach can achieve promising gains over other existing approaches in terms of noise-induced artifacts mitigation, edge details preservation, and accurate MPHP maps calculation.

  9. Blind motion image deblurring using nonconvex higher-order total variation model

    NASA Astrophysics Data System (ADS)

    Li, Weihong; Chen, Rui; Xu, Shangwen; Gong, Weiguo

    2016-09-01

    We propose a nonconvex higher-order total variation (TV) method for blind motion image deblurring. First, we introduce a nonconvex higher-order TV differential operator to define a new model of the blind motion image deblurring, which can effectively eliminate the staircase effect of the deblurred image; meanwhile, we employ an image sparse prior to improve the edge recovery quality. Second, to improve the accuracy of the estimated motion blur kernel, we use L1 norm and H1 norm as the blur kernel regularization term, considering the sparsity and smoothing of the motion blur kernel. Third, because it is difficult to solve the numerically computational complexity problem of the proposed model owing to the intrinsic nonconvexity, we propose a binary iterative strategy, which incorporates a reweighted minimization approximating scheme in the outer iteration, and a split Bregman algorithm in the inner iteration. And we also discuss the convergence of the proposed binary iterative strategy. Last, we conduct extensive experiments on both synthetic and real-world degraded images. The results demonstrate that the proposed method outperforms the previous representative methods in both quality of visual perception and quantitative measurement.

  10. Algebraic techniques for diagonalization of a split quaternion matrix in split quaternionic mechanics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jiang, Tongsong, E-mail: jiangtongsong@sina.com; Department of Mathematics, Heze University, Heze, Shandong 274015; Jiang, Ziwu

    In the study of the relation between complexified classical and non-Hermitian quantum mechanics, physicists found that there are links to quaternionic and split quaternionic mechanics, and this leads to the possibility of employing algebraic techniques of split quaternions to tackle some problems in complexified classical and quantum mechanics. This paper, by means of real representation of a split quaternion matrix, studies the problem of diagonalization of a split quaternion matrix and gives algebraic techniques for diagonalization of split quaternion matrices in split quaternionic mechanics.

  11. Accurate reconstruction of hyperspectral images from compressive sensing measurements

    NASA Astrophysics Data System (ADS)

    Greer, John B.; Flake, J. C.

    2013-05-01

    The emerging field of Compressive Sensing (CS) provides a new way to capture data by shifting the heaviest burden of data collection from the sensor to the computer on the user-end. This new means of sensing requires fewer measurements for a given amount of information than traditional sensors. We investigate the efficacy of CS for capturing HyperSpectral Imagery (HSI) remotely. We also introduce a new family of algorithms for constructing HSI from CS measurements with Split Bregman Iteration [Goldstein and Osher,2009]. These algorithms combine spatial Total Variation (TV) with smoothing in the spectral dimension. We examine models for three different CS sensors: the Coded Aperture Snapshot Spectral Imager-Single Disperser (CASSI-SD) [Wagadarikar et al.,2008] and Dual Disperser (CASSI-DD) [Gehm et al.,2007] cameras, and a hypothetical random sensing model closer to CS theory, but not necessarily implementable with existing technology. We simulate the capture of remotely sensed images by applying the sensor forward models to well-known HSI scenes - an AVIRIS image of Cuprite, Nevada and the HYMAP Urban image. To measure accuracy of the CS models, we compare the scenes constructed with our new algorithm to the original AVIRIS and HYMAP cubes. The results demonstrate the possibility of accurately sensing HSI remotely with significantly fewer measurements than standard hyperspectral cameras.

  12. Spectral Diffusion: An Algorithm for Robust Material Decomposition of Spectral CT Data

    PubMed Central

    Clark, Darin P.; Badea, Cristian T.

    2014-01-01

    Clinical successes with dual energy CT, aggressive development of energy discriminating x-ray detectors, and novel, target-specific, nanoparticle contrast agents promise to establish spectral CT as a powerful functional imaging modality. Common to all of these applications is the need for a material decomposition algorithm which is robust in the presence of noise. Here, we develop such an algorithm which uses spectrally joint, piece-wise constant kernel regression and the split Bregman method to iteratively solve for a material decomposition which is gradient sparse, quantitatively accurate, and minimally biased. We call this algorithm spectral diffusion because it integrates structural information from multiple spectral channels and their corresponding material decompositions within the framework of diffusion-like denoising algorithms (e.g. anisotropic diffusion, total variation, bilateral filtration). Using a 3D, digital bar phantom and a material sensitivity matrix calibrated for use with a polychromatic x-ray source, we quantify the limits of detectability (CNR = 5) afforded by spectral diffusion in the triple-energy material decomposition of iodine (3.1 mg/mL), gold (0.9 mg/mL), and gadolinium (2.9 mg/mL) concentrations. We then apply spectral diffusion to the in vivo separation of these three materials in the mouse kidneys, liver, and spleen. PMID:25296173

  13. Spectral diffusion: an algorithm for robust material decomposition of spectral CT data.

    PubMed

    Clark, Darin P; Badea, Cristian T

    2014-11-07

    Clinical successes with dual energy CT, aggressive development of energy discriminating x-ray detectors, and novel, target-specific, nanoparticle contrast agents promise to establish spectral CT as a powerful functional imaging modality. Common to all of these applications is the need for a material decomposition algorithm which is robust in the presence of noise. Here, we develop such an algorithm which uses spectrally joint, piecewise constant kernel regression and the split Bregman method to iteratively solve for a material decomposition which is gradient sparse, quantitatively accurate, and minimally biased. We call this algorithm spectral diffusion because it integrates structural information from multiple spectral channels and their corresponding material decompositions within the framework of diffusion-like denoising algorithms (e.g. anisotropic diffusion, total variation, bilateral filtration). Using a 3D, digital bar phantom and a material sensitivity matrix calibrated for use with a polychromatic x-ray source, we quantify the limits of detectability (CNR = 5) afforded by spectral diffusion in the triple-energy material decomposition of iodine (3.1 mg mL(-1)), gold (0.9 mg mL(-1)), and gadolinium (2.9 mg mL(-1)) concentrations. We then apply spectral diffusion to the in vivo separation of these three materials in the mouse kidneys, liver, and spleen.

  14. A feasibility study for compressed sensing combined phase contrast MR angiography reconstruction

    NASA Astrophysics Data System (ADS)

    Lee, Dong-Hoon; Hong, Cheol-Pyo; Lee, Man-Woo; Han, Bong-Soo

    2012-02-01

    Phase contrast magnetic resonance angiography (PC MRA) is a technique for flow velocity measurement and vessels visualization, simultaneously. The PC MRA takes long scan time because each flow encoding gradients which are composed bipolar gradient type need to reconstruct the angiography image. Moreover, it takes more image acquisition time when we use the PC MRA at the low-tesla MRI system. In this study, we studied and evaluation of feasibility for CS MRI reconstruction combined PC MRA which data acquired by low-tesla MRI system. We used non-linear reconstruction algorithm which named Bregman iteration for CS image reconstruction and validate the usefulness of CS combined PC MRA reconstruction technique. The results of CS reconstructed PC MRA images provide similar level of image quality between fully sampled reconstruction data and sparse sampled reconstruction using CS technique. Although our results used half of sampling ratio and do not used specification hardware device or performance which are improving the temporal resolution of MR image acquisition such as parallel imaging reconstruction using phased array coil or non-cartesian trajectory, we think that CS combined PC MRA technique will be helpful to increase the temporal resolution and at low-tesla MRI system.

  15. Low-dose 4D cardiac imaging in small animals using dual source micro-CT

    NASA Astrophysics Data System (ADS)

    Holbrook, M.; Clark, D. P.; Badea, C. T.

    2018-01-01

    Micro-CT is widely used in preclinical studies, generating substantial interest in extending its capabilities in functional imaging applications such as blood perfusion and cardiac function. However, imaging cardiac structure and function in mice is challenging due to their small size and rapid heart rate. To overcome these challenges, we propose and compare improvements on two strategies for cardiac gating in dual-source, preclinical micro-CT: fast prospective gating (PG) and uncorrelated retrospective gating (RG). These sampling strategies combined with a sophisticated iterative image reconstruction algorithm provide faster acquisitions and high image quality in low-dose 4D (i.e. 3D  +  Time) cardiac micro-CT. Fast PG is performed under continuous subject rotation which results in interleaved projection angles between cardiac phases. Thus, fast PG provides a well-sampled temporal average image for use as a prior in iterative reconstruction. Uncorrelated RG incorporates random delays during sampling to prevent correlations between heart rate and sampling rate. We have performed both simulations and animal studies to validate these new sampling protocols. Sampling times for 1000 projections using fast PG and RG were 2 and 3 min, respectively, and the total dose was 170 mGy each. Reconstructions were performed using a 4D iterative reconstruction technique based on the split Bregman method. To examine undersampling robustness, subsets of 500 and 250 projections were also used for reconstruction. Both sampling strategies in conjunction with our iterative reconstruction method are capable of resolving cardiac phases and provide high image quality. In general, for equal numbers of projections, fast PG shows fewer errors than RG and is more robust to undersampling. Our results indicate that only 1000-projection based reconstruction with fast PG satisfies a 5% error criterion in left ventricular volume estimation. These methods promise low-dose imaging with a wide range of preclinical applications in cardiac imaging.

  16. Alveolar Ridge Split Technique Using Piezosurgery with Specially Designed Tips

    PubMed Central

    Moro, Alessandro; Foresta, Enrico; Falchi, Marco; De Angelis, Paolo; D'Amato, Giuseppe; Pelo, Sandro

    2017-01-01

    The treatment of patients with atrophic ridge who need prosthetic rehabilitation is a common problem in oral and maxillofacial surgery. Among the various techniques introduced for the expansion of alveolar ridges with a horizontal bone deficit is the alveolar ridge split technique. The aim of this article is to give a description of some new tips that have been specifically designed for the treatment of atrophic ridges with transversal bone deficit. A two-step piezosurgical split technique is also described, based on specific osteotomies of the vestibular cortex and the use of a mandibular ramus graft as interpositional graft. A total of 15 patients were treated with the proposed new tips by our department. All the expanded areas were successful in providing an adequate width and height to insert implants according to the prosthetic plan and the proposed tips allowed obtaining the most from the alveolar ridge split technique and piezosurgery. These tips have made alveolar ridge split technique simple, safe, and effective for the treatment of horizontal and vertical bone defects. Furthermore the proposed piezosurgical split technique allows obtaining horizontal and vertical bone augmentation. PMID:28246596

  17. Alveolar Ridge Split Technique Using Piezosurgery with Specially Designed Tips.

    PubMed

    Moro, Alessandro; Gasparini, Giulio; Foresta, Enrico; Saponaro, Gianmarco; Falchi, Marco; Cardarelli, Lorenzo; De Angelis, Paolo; Forcione, Mario; Garagiola, Umberto; D'Amato, Giuseppe; Pelo, Sandro

    2017-01-01

    The treatment of patients with atrophic ridge who need prosthetic rehabilitation is a common problem in oral and maxillofacial surgery. Among the various techniques introduced for the expansion of alveolar ridges with a horizontal bone deficit is the alveolar ridge split technique. The aim of this article is to give a description of some new tips that have been specifically designed for the treatment of atrophic ridges with transversal bone deficit. A two-step piezosurgical split technique is also described, based on specific osteotomies of the vestibular cortex and the use of a mandibular ramus graft as interpositional graft. A total of 15 patients were treated with the proposed new tips by our department. All the expanded areas were successful in providing an adequate width and height to insert implants according to the prosthetic plan and the proposed tips allowed obtaining the most from the alveolar ridge split technique and piezosurgery. These tips have made alveolar ridge split technique simple, safe, and effective for the treatment of horizontal and vertical bone defects. Furthermore the proposed piezosurgical split technique allows obtaining horizontal and vertical bone augmentation.

  18. A Maximal Entropy Distribution Derivation of the Sharma-Taneja-Mittal Entropic Form

    NASA Astrophysics Data System (ADS)

    Scarfone, Antonio M.

    In this letter we derive the distribution maximizing the Sharma-Taneja-Mittal entropy under certain constrains by using an information inequality satisfied by the Br`egman divergence associated to this entropic form. The resulting maximal entropy distribution coincides with the one derived from the calculus according to the maximal entropy principle à la Jaynes.

  19. Brain MR image segmentation based on an improved active contour model

    PubMed Central

    Meng, Xiangrui; Gu, Wenya; Zhang, Jianwei

    2017-01-01

    It is often a difficult task to accurately segment brain magnetic resonance (MR) images with intensity in-homogeneity and noise. This paper introduces a novel level set method for simultaneous brain MR image segmentation and intensity inhomogeneity correction. To reduce the effect of noise, novel anisotropic spatial information, which can preserve more details of edges and corners, is proposed by incorporating the inner relationships among the neighbor pixels. Then the proposed energy function uses the multivariate Student's t-distribution to fit the distribution of the intensities of each tissue. Furthermore, the proposed model utilizes Hidden Markov random fields to model the spatial correlation between neigh-boring pixels/voxels. The means of the multivariate Student's t-distribution can be adaptively estimated by multiplying a bias field to reduce the effect of intensity inhomogeneity. In the end, we reconstructed the energy function to be convex and calculated it by using the Split Bregman method, which allows our framework for random initialization, thereby allowing fully automated applications. Our method can obtain the final result in less than 1 second for 2D image with size 256 × 256 and less than 300 seconds for 3D image with size 256 × 256 × 171. The proposed method was compared to other state-of-the-art segmentation methods using both synthetic and clinical brain MR images and increased the accuracies of the results more than 3%. PMID:28854235

  20. Piggyback transplantation with side-to-side cavocavostomy is an ideal technique for right split liver allograft implantation.

    PubMed

    Lerut, J; de Ville de Goyet, J; Donataccio, M; Reding, R; Otte, J B

    1994-11-01

    Split liver grafting has not gained wide acceptance mainly because of different vascular and biliary technical problems. A new technique of right split liver transplantation is described. The piggyback implantation technique, using wide side-to-side cavocavostomy overcomes problems encountered when sharing the superhepatic vena cava cuff between two livers and obtains optimal drainage of venous allograft outflow, thus avoiding extensive bleeding at the transection margin. This technique was successfully used in two adult recipients. Piggyback transplantation using wide side-to-side cavocavostomy allows easy and safe implantation of the right split liver allograft.

  1. Auditory Stream Segregation Improves Infants' Selective Attention to Target Tones Amid Distracters

    ERIC Educational Resources Information Center

    Smith, Nicholas A.; Trainor, Laurel J.

    2011-01-01

    This study examined the role of auditory stream segregation in the selective attention to target tones in infancy. Using a task adapted from Bregman and Rudnicky's 1975 study and implemented in a conditioned head-turn procedure, infant and adult listeners had to discriminate the temporal order of 2,200 and 2,400 Hz target tones presented alone,…

  2. Deterministic Compressed Sensing

    DTIC Science & Technology

    2011-11-01

    of the algorithm can be derived by using the Bregman divergence based on the Kullback - Leibler function, and an additive update...regularized goodness - of - fit objective function. In contrast to many CS approaches, however, we measure the fit of an esti- mate to the data using the...sensing is information theoretically possible using any (2k, )-RIP sensing matrix . The following celebrated results of Candès, Romberg and Tao

  3. Simultaneous deblurring and iterative reconstruction of CBCT for image guided brain radiosurgery.

    PubMed

    Hashemi, SayedMasoud; Song, William Y; Sahgal, Arjun; Lee, Young; Huynh, Christopher; Grouza, Vladimir; Nordström, Håkan; Eriksson, Markus; Dorenlot, Antoine; Régis, Jean Marie; Mainprize, James G; Ruschin, Mark

    2017-04-07

    One of the limiting factors in cone-beam CT (CBCT) image quality is system blur, caused by detector response, x-ray source focal spot size, azimuthal blurring, and reconstruction algorithm. In this work, we develop a novel iterative reconstruction algorithm that improves spatial resolution by explicitly accounting for image unsharpness caused by different factors in the reconstruction formulation. While the model-based iterative reconstruction techniques use prior information about the detector response and x-ray source, our proposed technique uses a simple measurable blurring model. In our reconstruction algorithm, denoted as simultaneous deblurring and iterative reconstruction (SDIR), the blur kernel can be estimated using the modulation transfer function (MTF) slice of the CatPhan phantom or any other MTF phantom, such as wire phantoms. The proposed image reconstruction formulation includes two regularization terms: (1) total variation (TV) and (2) nonlocal regularization, solved with a split Bregman augmented Lagrangian iterative method. The SDIR formulation preserves edges, eases the parameter adjustments to achieve both high spatial resolution and low noise variances, and reduces the staircase effect caused by regular TV-penalized iterative algorithms. The proposed algorithm is optimized for a point-of-care head CBCT unit for image-guided radiosurgery and is tested with CatPhan phantom, an anthropomorphic head phantom, and 6 clinical brain stereotactic radiosurgery cases. Our experiments indicate that SDIR outperforms the conventional filtered back projection and TV penalized simultaneous algebraic reconstruction technique methods (represented by adaptive steepest-descent POCS algorithm, ASD-POCS) in terms of MTF and line pair resolution, and retains the favorable properties of the standard TV-based iterative reconstruction algorithms in improving the contrast and reducing the reconstruction artifacts. It improves the visibility of the high contrast details in bony areas and the brain soft-tissue. For example, the results show the ventricles and some brain folds become visible in SDIR reconstructed images and the contrast of the visible lesions is effectively improved. The line-pair resolution was improved from 12 line-pair/cm in FBP to 14 line-pair/cm in SDIR. Adjusting the parameters of the ASD-POCS to achieve 14 line-pair/cm caused the noise variance to be higher than the SDIR. Using these parameters for ASD-POCS, the MTF of FBP and ASD-POCS were very close and equal to 0.7 mm -1 which was increased to 1.2 mm -1 by SDIR, at half maximum.

  4. Simultaneous deblurring and iterative reconstruction of CBCT for image guided brain radiosurgery

    NASA Astrophysics Data System (ADS)

    Hashemi, SayedMasoud; Song, William Y.; Sahgal, Arjun; Lee, Young; Huynh, Christopher; Grouza, Vladimir; Nordström, Håkan; Eriksson, Markus; Dorenlot, Antoine; Régis, Jean Marie; Mainprize, James G.; Ruschin, Mark

    2017-04-01

    One of the limiting factors in cone-beam CT (CBCT) image quality is system blur, caused by detector response, x-ray source focal spot size, azimuthal blurring, and reconstruction algorithm. In this work, we develop a novel iterative reconstruction algorithm that improves spatial resolution by explicitly accounting for image unsharpness caused by different factors in the reconstruction formulation. While the model-based iterative reconstruction techniques use prior information about the detector response and x-ray source, our proposed technique uses a simple measurable blurring model. In our reconstruction algorithm, denoted as simultaneous deblurring and iterative reconstruction (SDIR), the blur kernel can be estimated using the modulation transfer function (MTF) slice of the CatPhan phantom or any other MTF phantom, such as wire phantoms. The proposed image reconstruction formulation includes two regularization terms: (1) total variation (TV) and (2) nonlocal regularization, solved with a split Bregman augmented Lagrangian iterative method. The SDIR formulation preserves edges, eases the parameter adjustments to achieve both high spatial resolution and low noise variances, and reduces the staircase effect caused by regular TV-penalized iterative algorithms. The proposed algorithm is optimized for a point-of-care head CBCT unit for image-guided radiosurgery and is tested with CatPhan phantom, an anthropomorphic head phantom, and 6 clinical brain stereotactic radiosurgery cases. Our experiments indicate that SDIR outperforms the conventional filtered back projection and TV penalized simultaneous algebraic reconstruction technique methods (represented by adaptive steepest-descent POCS algorithm, ASD-POCS) in terms of MTF and line pair resolution, and retains the favorable properties of the standard TV-based iterative reconstruction algorithms in improving the contrast and reducing the reconstruction artifacts. It improves the visibility of the high contrast details in bony areas and the brain soft-tissue. For example, the results show the ventricles and some brain folds become visible in SDIR reconstructed images and the contrast of the visible lesions is effectively improved. The line-pair resolution was improved from 12 line-pair/cm in FBP to 14 line-pair/cm in SDIR. Adjusting the parameters of the ASD-POCS to achieve 14 line-pair/cm caused the noise variance to be higher than the SDIR. Using these parameters for ASD-POCS, the MTF of FBP and ASD-POCS were very close and equal to 0.7 mm-1 which was increased to 1.2 mm-1 by SDIR, at half maximum.

  5. Split liver transplantation: a reliable approach to expand donor pool.

    PubMed

    Yan, Ji-Qi; Becker, Thomas; Peng, Cheng-Hong; Li, Hong-Wei; Klempnauer, Juergen

    2005-08-01

    Orthotopic liver transplantation as a successful treatment of end-stage liver disease is hampered by a persistent lack of cadaveric organs. Split liver transplantation, which was first successfully performed by Medical School of Hannover in 1988, has become a mature surgical technique to expand the donor pool. Between 1993 and 1999, split liver transplantation activities have increased in Europe from 1.2% to 10.4% in all performed liver transplantations. Current data have strongly supported that the survival rate of patients after split liver transplantation is not significantly different from that of patients after whole-size orthotopic liver transplantation. The most important step of donor graft selection is surgeon's observation judged by the experience of individual transplant center. The paper aims to provide the guideline of donor selection, hepatic graft splitting, and recipient management as well. Medical School of Hannover has accumulated plentiful experience of split liver transplantation for more than 10 cases ever since 1998. Besides that, we also reviewed a variety of literatures from other famous European and American centers specialized in this field for many years. According to our experience combined with the view points of others, the donor should meet the following criteria as well: (1) age less than 50 years; (2) hemodynamics stable; (3) ICU less than 5 days; (4) Na less than 170 mmol/L or better if less than 150 mmol/L. In 1996 and 1997, the Hamburg group and the UCLA group separately introduced a breakthrough technique performing split liver transplantation in situ. Evidently, the in situ technique has been limited by prolonged time of donor organ procurement, coordination with other organ procurement teams, and even extra burden on donor hospital. Some groups, therefore, have restored the ex situ or bench splitting technique, and fortunately the transplant outcomes of the ex situ technique are equivalent to those of the in situ one. Recently some new techniques have been introduced to split the liver for two adult patients, including the split-cava technique. It is clear that the most important factor for determining the prognosis of the patient is the time of receiving liver transplantation, not the type of liver transplantation. We still need to pay close attention to the graft to recipient weight ratio (GRWR) and the UNOS classification or MELD score before the patient is subjected to split liver transplantation.

  6. Biomechanical comparison of a novel engine-driven ridge spreader and conventional ridge splitting techniques.

    PubMed

    Jung, Gyu-Un; Kim, Jun Hwan; Lim, Nam Hun; Yoon, Gil Ho; Han, Ji-Young

    2017-06-01

    Ridge splitting techniques are used for horizontal ridge augmentation in implant dentistry. Recently, a novel engine-driven ridge splitting technique was introduced. This study compared the mechanical forces produced by conventional and engine-driven ridge splitting techniques in porcine mandibles. In 33 pigs, mandibular premolar areas were selected for the ridge splitting procedures, designed as a randomized split-mouth study. The conventional group underwent a chisel-and-mallet procedure (control group, n = 20), and percussive impulse (Newton second, Ns) was measured using a sensor attached to the mallet. In the engine-driven ridge spreader group (test group, n = 23), a load cell was used to measure torque values (Newton centimeter, Ncm). Horizontal acceleration generated during procedures (control group, n = 10 and test group, n = 10) was compared between the groups. After ridge splitting, the alveolar crest width was significantly increased both in the control (1.23 ± 0.45 mm) and test (0.98 ± 0.41 mm) groups with no significant differences between the groups. The average impulse of the control group was 4.74 ± 1.05 Ns. Torque generated by rotation in the test group was 9.07 ± 2.15 Ncm. Horizontal acceleration was significantly less in the test group (0.82 ± 1.05 g) than the control group (64.07 ± 42.62 g) (P < 0.001). Narrow edentulous ridges can be expanded by novel engine-driven ridge spreaders. Within the limits of this study, the results suggested that an engine-driven ridge splitting technique may be less traumatic and less invasive than a conventional ridge splitting technique. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Multi-energy CT based on a prior rank, intensity and sparsity model (PRISM).

    PubMed

    Gao, Hao; Yu, Hengyong; Osher, Stanley; Wang, Ge

    2011-11-01

    We propose a compressive sensing approach for multi-energy computed tomography (CT), namely the prior rank, intensity and sparsity model (PRISM). To further compress the multi-energy image for allowing the reconstruction with fewer CT data and less radiation dose, the PRISM models a multi-energy image as the superposition of a low-rank matrix and a sparse matrix (with row dimension in space and column dimension in energy), where the low-rank matrix corresponds to the stationary background over energy that has a low matrix rank, and the sparse matrix represents the rest of distinct spectral features that are often sparse. Distinct from previous methods, the PRISM utilizes the generalized rank, e.g., the matrix rank of tight-frame transform of a multi-energy image, which offers a way to characterize the multi-level and multi-filtered image coherence across the energy spectrum. Besides, the energy-dependent intensity information can be incorporated into the PRISM in terms of the spectral curves for base materials, with which the restoration of the multi-energy image becomes the reconstruction of the energy-independent material composition matrix. In other words, the PRISM utilizes prior knowledge on the generalized rank and sparsity of a multi-energy image, and intensity/spectral characteristics of base materials. Furthermore, we develop an accurate and fast split Bregman method for the PRISM and demonstrate the superior performance of the PRISM relative to several competing methods in simulations.

  8. Low-dose cerebral perfusion computed tomography image restoration via low-rank and total variation regularizations

    PubMed Central

    Niu, Shanzhou; Zhang, Shanli; Huang, Jing; Bian, Zhaoying; Chen, Wufan; Yu, Gaohang; Liang, Zhengrong; Ma, Jianhua

    2016-01-01

    Cerebral perfusion x-ray computed tomography (PCT) is an important functional imaging modality for evaluating cerebrovascular diseases and has been widely used in clinics over the past decades. However, due to the protocol of PCT imaging with repeated dynamic sequential scans, the associative radiation dose unavoidably increases as compared with that used in conventional CT examinations. Minimizing the radiation exposure in PCT examination is a major task in the CT field. In this paper, considering the rich similarity redundancy information among enhanced sequential PCT images, we propose a low-dose PCT image restoration model by incorporating the low-rank and sparse matrix characteristic of sequential PCT images. Specifically, the sequential PCT images were first stacked into a matrix (i.e., low-rank matrix), and then a non-convex spectral norm/regularization and a spatio-temporal total variation norm/regularization were then built on the low-rank matrix to describe the low rank and sparsity of the sequential PCT images, respectively. Subsequently, an improved split Bregman method was adopted to minimize the associative objective function with a reasonable convergence rate. Both qualitative and quantitative studies were conducted using a digital phantom and clinical cerebral PCT datasets to evaluate the present method. Experimental results show that the presented method can achieve images with several noticeable advantages over the existing methods in terms of noise reduction and universal quality index. More importantly, the present method can produce more accurate kinetic enhanced details and diagnostic hemodynamic parameter maps. PMID:27440948

  9. Measurement of fracture toughness by nanoindentation methods: Recent advances and future challenges

    DOE PAGES

    Sebastiani, Marco; Johanns, K. E.; Herbert, Erik G.; ...

    2015-04-30

    In this study, we describe recent advances and developments for the measurement of fracture toughness at small scales by the use of nanoindentation-based methods including techniques based on micro-cantilever beam bending and micro-pillar splitting. A critical comparison of the techniques is made by testing a selected group of bulk and thin film materials. For pillar splitting, cohesive zone finite element simulations are used to validate a simple relationship between the critical load at failure, the pillar radius, and the fracture toughness for a range of material properties and coating/substrate combinations. The minimum pillar diameter required for nucleation and growth ofmore » a crack during indentation is also estimated. An analysis of pillar splitting for a film on a dissimilar substrate material shows that the critical load for splitting is relatively insensitive to the substrate compliance for a large range of material properties. Experimental results from a selected group of materials show good agreement between single cantilever and pillar splitting methods, while a discrepancy of ~25% is found between the pillar splitting technique and double-cantilever testing. It is concluded that both the micro-cantilever and pillar splitting techniques are valuable methods for micro-scale assessment of fracture toughness of brittle ceramics, provided the underlying assumptions can be validated. Although the pillar splitting method has some advantages because of the simplicity of sample preparation and testing, it is not applicable to most metals because their higher toughness prevents splitting, and in this case, micro-cantilever bend testing is preferred.« less

  10. Joint synthetic aperture radar plus ground moving target indicator from single-channel radar using compressive sensing

    DOEpatents

    Thompson, Douglas; Hallquist, Aaron; Anderson, Hyrum

    2017-10-17

    The various embodiments presented herein relate to utilizing an operational single-channel radar to collect and process synthetic aperture radar (SAR) and ground moving target indicator (GMTI) imagery from a same set of radar returns. In an embodiment, data is collected by randomly staggering a slow-time pulse repetition interval (PRI) over a SAR aperture such that a number of transmitted pulses in the SAR aperture is preserved with respect to standard SAR, but many of the pulses are spaced very closely enabling movers (e.g., targets) to be resolved, wherein a relative velocity of the movers places them outside of the SAR ground patch. The various embodiments of image reconstruction can be based on compressed sensing inversion from undersampled data, which can be solved efficiently using such techniques as Bregman iteration. The various embodiments enable high-quality SAR reconstruction, and high-quality GMTI reconstruction from the same set of radar returns.

  11. Refinements in pectus carinatum correction: the pectoralis muscle split technique.

    PubMed

    Schwabegger, Anton H; Jeschke, Johannes; Schuetz, Tanja; Del Frari, Barbara

    2008-04-01

    The standard approach for correction of pectus carinatum deformity includes elevation of the pectoralis major and rectus abdominis muscle from the sternum and adjacent ribs. A postoperative restriction of shoulder activity for several weeks is necessary to allow stable healing of the elevated muscles. To reduce postoperative immobilization, we present a modified approach to the parasternal ribs using a pectoralis muscle split technique. At each level of rib cartilage resection, the pectoralis muscle is split along the direction of its fibers instead of elevating the entire muscle as performed with the standard technique. From July 2000 to May 2007, we successfully used this technique in 33 patients with pectus carinatum deformity. After the muscle split approach, patients returned to full unrestricted shoulder activity as early as 3 weeks postoperatively, compared to 6 weeks in patients treated with muscle flap elevation. Postoperative pain was reduced and the patients were discharged earlier from the hospital than following the conventional approach. The muscle split technique is a modified surgical approach to the parasternal ribs in patients with pectus carinatum deformity. It helps to maintain pectoralis muscle vascularization and function and can reduce postoperative pain, hospitalization, and rehabilitation period.

  12. TH-CD-202-04: Evaluation of Virtual Non-Contrast Images From a Novel Split-Filter Dual-Energy CT Technique

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, J; Szczykutowicz, T; Bayouth, J

    Purpose: To compare the ability of two dual-energy CT techniques, a novel split-filter single-source technique of superior temporal resolution against an established sequential-scan technique, to remove iodine contrast from images with minimal impact on CT number accuracy. Methods: A phantom containing 8 tissue substitute materials and vials of varying iodine concentrations (1.7–20.1 mg I /mL) was imaged using a Siemens Edge CT scanner. Dual-energy virtual non-contrast (VNC) images were generated using the novel split-filter technique, in which a 120kVp spectrum is filtered by tin and gold to create high- and low-energy spectra with < 1 second temporal separation between themore » acquisition of low- and high-energy data. Additionally, VNC images were generated with the sequential-scan technique (80 and 140kVp) for comparison. CT number accuracy was evaluated for all materials at 15, 25, and 35mGy CTDIvol. Results: The spectral separation was greater for the sequential-scan technique than the split-filter technique with dual-energy ratios of 2.18 and 1.26, respectively. Both techniques successfully removed iodine contrast, resulting in mean CT numbers within 60HU of 0HU (split-filter) and 40HU of 0HU (sequential-scan) for all iodine concentrations. Additionally, for iodine vials of varying diameter (2–20 mm) with the same concentration (9.9 mg I /mL), the system accurately detected iodine for all sizes investigated. Both dual-energy techniques resulted in reduced CT numbers for bone materials (by >400HU for the densest bone). Increasing the imaging dose did not improve the CT number accuracy for bone in VNC images. Conclusion: VNC images from the split-filter technique successfully removed iodine contrast. These results demonstrate a potential for improving dose calculation accuracy and reducing patient imaging dose, while achieving superior temporal resolution in comparison sequential scans. For both techniques, inaccuracies in CT numbers for bone materials necessitate consideration for radiation therapy treatment planning.« less

  13. Regeneration of the Adult Rat Spinal Cord in Response to Ensheathing Cells and Methylprednisolone

    DTIC Science & Technology

    2002-01-01

    me in academics and research, and also as my friend. I thank Dr. Linda L. Porter, for her continuous efforts on my behalf as the Chairperson of...and Spinal Cord Injury Program. We are grateful to Drs. Barbara S. Bregman and Linda L. Porter for their wonderful suggestions and guidance; to Anna...ES, Pietronigro DD, Seligman ML (1980) The free radical pathology and the microcirculation in the major central nervous system disorders. Acta

  14. Sparse Recovery via Differential Inclusions

    DTIC Science & Technology

    2014-07-01

    2242. [Wai09] Martin J. Wainwright, Sharp thresholds for high-dimensional and noisy spar- sity recovery using l1 -constrained quadratic programming...solution, (1.11) βt = { 0, if t < 1/y; y(1− e−κ(t−1/y)), otherwise, which converges to the unbiased Bregman ISS estimator exponentially fast. Let us ...are not given the support set S, so the following two prop- erties are used to evaluate the performance of an estimator β̂. 1. Model selection

  15. Joint reconstruction via coupled Bregman iterations with applications to PET-MR imaging

    NASA Astrophysics Data System (ADS)

    Rasch, Julian; Brinkmann, Eva-Maria; Burger, Martin

    2018-01-01

    Joint reconstruction has recently attracted a lot of attention, especially in the field of medical multi-modality imaging such as PET-MRI. Most of the developed methods rely on the comparison of image gradients, or more precisely their location, direction and magnitude, to make use of structural similarities between the images. A challenge and still an open issue for most of the methods is to handle images in entirely different scales, i.e. different magnitudes of gradients that cannot be dealt with by a global scaling of the data. We propose the use of generalized Bregman distances and infimal convolutions thereof with regard to the well-known total variation functional. The use of a total variation subgradient respectively the involved vector field rather than an image gradient naturally excludes the magnitudes of gradients, which in particular solves the scaling behavior. Additionally, the presented method features a weighting that allows to control the amount of interaction between channels. We give insights into the general behavior of the method, before we further tailor it to a particular application, namely PET-MRI joint reconstruction. To do so, we compute joint reconstruction results from blurry Poisson data for PET and undersampled Fourier data from MRI and show that we can gain a mutual benefit for both modalities. In particular, the results are superior to the respective separate reconstructions and other joint reconstruction methods.

  16. Split-step eigenvector-following technique for exploring enthalpy landscapes at absolute zero.

    PubMed

    Mauro, John C; Loucks, Roger J; Balakrishnan, Jitendra

    2006-03-16

    The mapping of enthalpy landscapes is complicated by the coupling of particle position and volume coordinates. To address this issue, we have developed a new split-step eigenvector-following technique for locating minima and transition points in an enthalpy landscape at absolute zero. Each iteration is split into two steps in order to independently vary system volume and relative atomic coordinates. A separate Lagrange multiplier is used for each eigendirection in order to provide maximum flexibility in determining step sizes. This technique will be useful for mapping the enthalpy landscapes of bulk systems such as supercooled liquids and glasses.

  17. Automatic segmentation for brain MR images via a convex optimized segmentation and bias field correction coupled model.

    PubMed

    Chen, Yunjie; Zhao, Bo; Zhang, Jianwei; Zheng, Yuhui

    2014-09-01

    Accurate segmentation of magnetic resonance (MR) images remains challenging mainly due to the intensity inhomogeneity, which is also commonly known as bias field. Recently active contour models with geometric information constraint have been applied, however, most of them deal with the bias field by using a necessary pre-processing step before segmentation of MR data. This paper presents a novel automatic variational method, which can segment brain MR images meanwhile correcting the bias field when segmenting images with high intensity inhomogeneities. We first define a function for clustering the image pixels in a smaller neighborhood. The cluster centers in this objective function have a multiplicative factor that estimates the bias within the neighborhood. In order to reduce the effect of the noise, the local intensity variations are described by the Gaussian distributions with different means and variances. Then, the objective functions are integrated over the entire domain. In order to obtain the global optimal and make the results independent of the initialization of the algorithm, we reconstructed the energy function to be convex and calculated it by using the Split Bregman theory. A salient advantage of our method is that its result is independent of initialization, which allows robust and fully automated application. Our method is able to estimate the bias of quite general profiles, even in 7T MR images. Moreover, our model can also distinguish regions with similar intensity distribution with different variances. The proposed method has been rigorously validated with images acquired on variety of imaging modalities with promising results. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. GPU-accelerated iterative reconstruction for limited-data tomography in CBCT systems.

    PubMed

    de Molina, Claudia; Serrano, Estefania; Garcia-Blas, Javier; Carretero, Jesus; Desco, Manuel; Abella, Monica

    2018-05-15

    Standard cone-beam computed tomography (CBCT) involves the acquisition of at least 360 projections rotating through 360 degrees. Nevertheless, there are cases in which only a few projections can be taken in a limited angular span, such as during surgery, where rotation of the source-detector pair is limited to less than 180 degrees. Reconstruction of limited data with the conventional method proposed by Feldkamp, Davis and Kress (FDK) results in severe artifacts. Iterative methods may compensate for the lack of data by including additional prior information, although they imply a high computational burden and memory consumption. We present an accelerated implementation of an iterative method for CBCT following the Split Bregman formulation, which reduces computational time through GPU-accelerated kernels. The implementation enables the reconstruction of large volumes (>1024 3 pixels) using partitioning strategies in forward- and back-projection operations. We evaluated the algorithm on small-animal data for different scenarios with different numbers of projections, angular span, and projection size. Reconstruction time varied linearly with the number of projections and quadratically with projection size but remained almost unchanged with angular span. Forward- and back-projection operations represent 60% of the total computational burden. Efficient implementation using parallel processing and large-memory management strategies together with GPU kernels enables the use of advanced reconstruction approaches which are needed in limited-data scenarios. Our GPU implementation showed a significant time reduction (up to 48 ×) compared to a CPU-only implementation, resulting in a total reconstruction time from several hours to few minutes.

  19. Limited angle breast ultrasound tomography with a priori information and artifact removal

    NASA Astrophysics Data System (ADS)

    Jintamethasawat, Rungroj; Zhu, Yunhao; Kripfgans, Oliver D.; Yuan, Jie; Goodsitt, Mitchell M.; Carson, Paul L.

    2017-03-01

    In B-mode images from dual-sided ultrasound, it has been shown that by delineating structures suspected of being relatively homogeneous, one can enhance limited angle tomography to produce speed of sound images in the same view as X-ray Digital Breast Tomography (DBT). This could allow better breast cancer detection and discrimination, as well as improved registration of the ultrasound and X-ray images, because of the similarity of SOS and X-ray contrast in the breast. However, this speed of sound reconstruction method relies strongly on B-mode or other reflection mode segmentation. If that information is limited or incorrect, artifacts will appear in the reconstructed images. Therefore, the iterative speed of sound reconstruction algorithm has been modified in a manner of simultaneously utilizing the image segmentations and removing most artifacts. The first step of incorporating a priori information is solved by any nonlinearnonconvex optimization method while artifact removal is accomplished by employing the fast split Bregman method to perform total-variation (TV) regularization for image denoising. The proposed method was demonstrated in simplified simulations of our dual-sided ultrasound scanner. To speed these computations two opposed 40-element ultrasound linear arrays with 0.5 MHz center frequency were simulated for imaging objects in a uniform background. The proposed speed of sound reconstruction method worked well with both bent-ray and full-wave inversion methods. This is also the first demonstration of successful full-wave medical ultrasound tomography in the limited angle geometry. Presented results lend credibility to a possible translation of this method to clinical breast imaging.

  20. Regularization Parameter Selection for Nonlinear Iterative Image Restoration and MRI Reconstruction Using GCV and SURE-Based Methods

    PubMed Central

    Ramani, Sathish; Liu, Zhihao; Rosen, Jeffrey; Nielsen, Jon-Fredrik; Fessler, Jeffrey A.

    2012-01-01

    Regularized iterative reconstruction algorithms for imaging inverse problems require selection of appropriate regularization parameter values. We focus on the challenging problem of tuning regularization parameters for nonlinear algorithms for the case of additive (possibly complex) Gaussian noise. Generalized cross-validation (GCV) and (weighted) mean-squared error (MSE) approaches (based on Stein's Unbiased Risk Estimate— SURE) need the Jacobian matrix of the nonlinear reconstruction operator (representative of the iterative algorithm) with respect to the data. We derive the desired Jacobian matrix for two types of nonlinear iterative algorithms: a fast variant of the standard iterative reweighted least-squares method and the contemporary split-Bregman algorithm, both of which can accommodate a wide variety of analysis- and synthesis-type regularizers. The proposed approach iteratively computes two weighted SURE-type measures: Predicted-SURE and Projected-SURE (that require knowledge of noise variance σ2), and GCV (that does not need σ2) for these algorithms. We apply the methods to image restoration and to magnetic resonance image (MRI) reconstruction using total variation (TV) and an analysis-type ℓ1-regularization. We demonstrate through simulations and experiments with real data that minimizing Predicted-SURE and Projected-SURE consistently lead to near-MSE-optimal reconstructions. We also observed that minimizing GCV yields reconstruction results that are near-MSE-optimal for image restoration and slightly sub-optimal for MRI. Theoretical derivations in this work related to Jacobian matrix evaluations can be extended, in principle, to other types of regularizers and reconstruction algorithms. PMID:22531764

  1. A Novel Approach with Time-Splitting Spectral Technique for the Coupled Schrödinger-Boussinesq Equations Involving Riesz Fractional Derivative

    NASA Astrophysics Data System (ADS)

    Saha Ray, S.

    2017-09-01

    In the present paper the Riesz fractional coupled Schrödinger-Boussinesq (S-B) equations have been solved by the time-splitting Fourier spectral (TSFS) method. This proposed technique is utilized for discretizing the Schrödinger like equation and further, a pseudospectral discretization has been employed for the Boussinesq-like equation. Apart from that an implicit finite difference approach has also been proposed to compare the results with the solutions obtained from the time-splitting technique. Furthermore, the time-splitting method is proved to be unconditionally stable. The error norms along with the graphical solutions have also been presented here. Supported by NBHM, Mumbai, under Department of Atomic Energy, Government of India vide Grant No. 2/48(7)/2015/NBHM (R.P.)/R&D II/11403

  2. Relational Learning via Collective Matrix Factorization

    DTIC Science & Technology

    2008-06-01

    well-known example of such a schema is pLSI- pHITS [13], which models document-word counts and document-document citations: E1 = words and E2 = E3...relational co- clustering include pLSI, pLSI- pHITS , the symmetric block models of Long et. al. [23, 24, 25], and Bregman tensor clustering [5] (which can...to pLSI- pHITS In this section we provide an example where the additional flexibility of collective matrix factorization leads to better results; and

  3. Jensen-Bregman LogDet Divergence for Efficient Similarity Computations on Positive Definite Tensors

    DTIC Science & Technology

    2012-05-02

    function of Legendre-type on int(domS) [29]. From (7) the following properties of dφ(x, y) are apparent: strict convexity in x; asym- metry; non ...tensor imaging. An important task in all of these applications is to compute the distance between covariance matrices using a (dis)similarity function ...important task in all of these applications is to compute the distance between covariance matrices using a (dis)similarity function , for which the natural

  4. Splitting livers: Trans-hilar or trans-umbilical division? Technical aspects and comparative outcomes.

    PubMed

    de Ville de Goyet, J; di Francesco, F; Sottani, V; Grimaldi, C; Tozzi, A E; Monti, L; Muiesan, P

    2015-08-01

    Controversy remains about the best line of division for liver splitting, through Segment IV or through the umbilical fissure. Both techniques are currently used, with the choice varying between surgical teams in the absence of an evidence-based choice. We conducted a single-center retrospective analysis of 47 left split liver grafts that were procured with two different division techniques: "classical" (N = 28, Group A) or through the umbilical fissure and plate (N = 19, Group B). The allocation of recipients to each group was at random; a single transplant team performed all transplantations. Demographics, characteristics, technical aspects, and outcomes were similar in both groups. The grafts in Group A, prepared with the classical technique, were procured more often with a single BD orifice compared with the grafts in Group B; however, this was not associated with a higher incidence of biliary problems in this series of transplants (96% actual graft survival rate [median ± s.d. 26 ± 20 months]). Both techniques provide good quality split grafts and an excellent outcome; surgical expertise with a given technique is more relevant than the technique itself. The classical technique, however, seems to be more flexible in various ways, and surgeons may find it to be preferable. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. Application of particle splitting method for both hydrostatic and hydrodynamic cases in SPH

    NASA Astrophysics Data System (ADS)

    Liu, W. T.; Sun, P. N.; Ming, F. R.; Zhang, A. M.

    2018-01-01

    Smoothed particle hydrodynamics (SPH) method with numerical diffusive terms shows satisfactory stability and accuracy in some violent fluid-solid interaction problems. However, in most simulations, uniform particle distributions are used and the multi-resolution, which can obviously improve the local accuracy and the overall computational efficiency, has seldom been applied. In this paper, a dynamic particle splitting method is applied and it allows for the simulation of both hydrostatic and hydrodynamic problems. The splitting algorithm is that, when a coarse (mother) particle enters the splitting region, it will be split into four daughter particles, which inherit the physical parameters of the mother particle. In the particle splitting process, conservations of mass, momentum and energy are ensured. Based on the error analysis, the splitting technique is designed to allow the optimal accuracy at the interface between the coarse and refined particles and this is particularly important in the simulation of hydrostatic cases. Finally, the scheme is validated by five basic cases, which demonstrate that the present SPH model with a particle splitting technique is of high accuracy and efficiency and is capable for the simulation of a wide range of hydrodynamic problems.

  6. Bad splits in bilateral sagittal split osteotomy: systematic review and meta-analysis of reported risk factors.

    PubMed

    Steenen, S A; van Wijk, A J; Becking, A G

    2016-08-01

    An unfavourable and unanticipated pattern of the bilateral sagittal split osteotomy (BSSO) is generally referred to as a 'bad split'. Patient factors predictive of a bad split reported in the literature are controversial. Suggested risk factors are reviewed in this article. A systematic review was undertaken, yielding a total of 30 studies published between 1971 and 2015 reporting the incidence of bad split and patient age, and/or surgical technique employed, and/or the presence of third molars. These included 22 retrospective cohort studies, six prospective cohort studies, one matched-pair analysis, and one case series. Spearman's rank correlation showed a statistically significant but weak correlation between increasing average age and increasing occurrence of bad splits in 18 studies (ρ=0.229; P<0.01). No comparative studies were found that assessed the incidence of bad split among the different splitting techniques. A meta-analysis pooling the effect sizes of seven cohort studies showed no significant difference in the incidence of bad split between cohorts of patients with third molars present and concomitantly removed during surgery, and patients in whom third molars were removed at least 6 months preoperatively (odds ratio 1.16, 95% confidence interval 0.73-1.85, Z=0.64, P=0.52). In summary, there is no robust evidence to date to show that any risk factor influences the incidence of bad split. Copyright © 2016 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  7. Splitting methods for low Mach number Euler and Navier-Stokes equations

    NASA Technical Reports Server (NTRS)

    Abarbanel, Saul; Dutt, Pravir; Gottlieb, David

    1987-01-01

    Examined are some splitting techniques for low Mach number Euler flows. Shortcomings of some of the proposed methods are pointed out and an explanation for their inadequacy suggested. A symmetric splitting for both the Euler and Navier-Stokes equations is then presented which removes the stiffness of these equations when the Mach number is small. The splitting is shown to be stable.

  8. Minimally Invasive Removal of an Intradural Cervical Tumor : Assessment of a Combined Split-Spinous Laminectomy and Quadrant Tube Retractor System Technique

    PubMed Central

    Kwak, Young-Seok; Cho, Dae-Chul; Kim, Young-Baeg

    2012-01-01

    Conventional laminectomy is the most popular technique for the complete removal of intradural spinal tumors. In particular, the central portion intramedullary tumor and large intradural extramedullary tumor often require a total laminectomy for the midline myelotomy, sufficient decompression, and adequate visualization. However, this technique has the disadvantages of a wide incision, extensive periosteal muscle dissection, and bony structural injury. Recently, split-spinous laminectomy and tubular retractor systems were found to decrease postoperative muscle injuries, skin incision size and discomfort. The combined technique of split-spinous laminectomy, using a quadrant tube retractor system allows for an excellent exposure of the tumor with minimal trauma of the surrounding tissue. We propose that this technique offers possible advantages over the traditional open tumor removal of the intradural spinal cord tumors, which covers one or two cervical levels and requires a total laminectomy. PMID:23133739

  9. Optimal projection method determination by Logdet Divergence and perturbed von-Neumann Divergence.

    PubMed

    Jiang, Hao; Ching, Wai-Ki; Qiu, Yushan; Cheng, Xiao-Qing

    2017-12-14

    Positive semi-definiteness is a critical property in kernel methods for Support Vector Machine (SVM) by which efficient solutions can be guaranteed through convex quadratic programming. However, a lot of similarity functions in applications do not produce positive semi-definite kernels. We propose projection method by constructing projection matrix on indefinite kernels. As a generalization of the spectrum method (denoising method and flipping method), the projection method shows better or comparable performance comparing to the corresponding indefinite kernel methods on a number of real world data sets. Under the Bregman matrix divergence theory, we can find suggested optimal λ in projection method using unconstrained optimization in kernel learning. In this paper we focus on optimal λ determination, in the pursuit of precise optimal λ determination method in unconstrained optimization framework. We developed a perturbed von-Neumann divergence to measure kernel relationships. We compared optimal λ determination with Logdet Divergence and perturbed von-Neumann Divergence, aiming at finding better λ in projection method. Results on a number of real world data sets show that projection method with optimal λ by Logdet divergence demonstrate near optimal performance. And the perturbed von-Neumann Divergence can help determine a relatively better optimal projection method. Projection method ia easy to use for dealing with indefinite kernels. And the parameter embedded in the method can be determined through unconstrained optimization under Bregman matrix divergence theory. This may provide a new way in kernel SVMs for varied objectives.

  10. Extraction of decision rules via imprecise probabilities

    NASA Astrophysics Data System (ADS)

    Abellán, Joaquín; López, Griselda; Garach, Laura; Castellano, Javier G.

    2017-05-01

    Data analysis techniques can be applied to discover important relations among features. This is the main objective of the Information Root Node Variation (IRNV) technique, a new method to extract knowledge from data via decision trees. The decision trees used by the original method were built using classic split criteria. The performance of new split criteria based on imprecise probabilities and uncertainty measures, called credal split criteria, differs significantly from the performance obtained using the classic criteria. This paper extends the IRNV method using two credal split criteria: one based on a mathematical parametric model, and other one based on a non-parametric model. The performance of the method is analyzed using a case study of traffic accident data to identify patterns related to the severity of an accident. We found that a larger number of rules is generated, significantly supplementing the information obtained using the classic split criteria.

  11. Longitudinal fibre splitting in muscular dystrophy: a serial cinematographic study

    PubMed Central

    Isaacs, Edward R.; Bradley, Walter G.; Henderson, Gerald

    1973-01-01

    A technique of block surface-staining and serial cinematography was modified to review serial sections of normal and dystrophic muscle from the Bar Harbor 129 Re strain of mice as a preliminary study of fibre splitting in dystrophic muscle. Using this technique, muscle fibres were reconstructed for up to 1·5 mm of their length without difficulty. Split fibres were identified only when the actual separation of fibres was observed. Splitting was seen to be a significant cause of the variations in fibre diameter and was at times responsible for the formation of groups of small atrophic fibres which resembled those seen in denervation atrophy. Complex multiple splitting and recombination of daughter and parent fibres was also observed and reconstructed to scale. These results may have considerable significance for the interpretation of physiological data on both human and murine dystrophic muscle. Images PMID:4753877

  12. Application of split window technique to TIMS data

    NASA Technical Reports Server (NTRS)

    Matsunaga, Tsuneo; Rokugawa, Shuichi; Ishii, Yoshinori

    1992-01-01

    Absorptions by the atmosphere in thermal infrared region are mainly due to water vapor, carbon dioxide, and ozone. As the content of water vapor in the atmosphere greatly changes according to weather conditions, it is important to know its amount between the sensor and the ground for atmospheric corrections of thermal Infrared Multispectral Scanner (TIMS) data (i.e. radiosonde). On the other hand, various atmospheric correction techniques were already developed for sea surface temperature estimations from satellites. Among such techniques, Split Window technique, now widely used for AVHRR (Advanced Very High Resolution Radiometer), uses no radiosonde or any kind of supplementary data but a difference between observed brightness temperatures in two channels for estimating atmospheric effects. Applications of Split Window technique to TIMS data are discussed because availability of atmospheric profile data is not clear when ASTER operates. After these theoretical discussions, the technique is experimentally applied to TIMS data at three ground targets and results are compared with atmospherically corrected data using LOWTRAN 7 with radiosonde data.

  13. User Feedback Procedures; Part III of Scientific Report No. ISR-18, Information Storage and Retrieval...

    ERIC Educational Resources Information Center

    Cornell Univ., Ithaca, NY. Dept. of Computer Science.

    Part Three of this five part report on Salton's Magical Automatic Retriever of Texts (SMART) project contains four papers. The first: "Variations on the Query Splitting Technique with Relevance Feedback" by T. P. Baker discusses some experiments in relevance feedback performed with variations on the technique of query splitting. The…

  14. Chemistry-split techniques for viscous reactive blunt body flow computations

    NASA Technical Reports Server (NTRS)

    Li, C. P.

    1987-01-01

    The weak-coupling structure between the fluid and species equations has been exploited and resulted in three, closely related, time-iterative implicit techniques. While the primitive variables are solved in two separated groups and each by an Alternating Direction Implicit (ADI) factorization scheme, the rate-species Jacobian can be treated in either full or diagonal matrix form, or simply ignored. The latter two versions render the split technique to solving for species as scalar rather than vector variables. The solution is completed at the end of each iteration after determining temperature and pressure from the flow density, energy and species concentrations. Numerical experimentation has shown that the split scalar technique, using partial rate Jacobian, yields the best overall stability and consistency. Satisfactory viscous solutions were obtained for an ellipsoidal body of axis ratio 3:1 at Mach 35 and an angle of attack of 20 degrees.

  15. Technique for the application of a streamer-type fish tag

    USGS Publications Warehouse

    Joeris, Leonard S.

    1953-01-01

    Principal features of the technique are: attachment of the plastic tag by means of a nylon-thread loop prepared in advance of field work; use of a curved surgical needle with cutting edge and a split eye for application of the tag. The procedures for splitting the needle's eye and for applying the tag are described and illustrated by a series of photographs.

  16. Classroom Modified Split-Root Technique and Its Application in a Plant Habitat Selection Experiment at the College Level

    ERIC Educational Resources Information Center

    Elliott, Shannon S.; Winter, Peggy A.

    2011-01-01

    The split-root technique produces a plant with two equal root masses. Traditionally, the two root masses of the single plant are cultivated in adjacent pots with or without roots from competitors for the purpose of elucidating habitat preferences. We have tailored this technology for the classroom, adjusting protocols to match resources and time…

  17. Numerical simulation and experiment on multilayer stagger-split die.

    PubMed

    Liu, Zhiwei; Li, Mingzhe; Han, Qigang; Yang, Yunfei; Wang, Bolong; Sui, Zhou

    2013-05-01

    A novel ultra-high pressure device, multilayer stagger-split die, has been constructed based on the principle of "dividing dies before cracking." Multilayer stagger-split die includes an encircling ring and multilayer assemblages, and the mating surfaces of the multilayer assemblages are mutually staggered between adjacent layers. In this paper, we investigated the stressing features of this structure through finite element techniques, and the results were compared with those of the belt type die and single split die. The contrast experiments were also carried out to test the bearing pressure performance of multilayer stagger-split die. It is concluded that the stress distributions are reasonable and the materials are utilized effectively for multilayer stagger-split die. And experiments indicate that the multilayer stagger-split die can bear the greatest pressure.

  18. Split thickness skin graft for cervicovaginal reconstruction in congenital atresia of cervix.

    PubMed

    Zhang, Xuyin; Han, Tiantian; Ding, Jingxin; Hua, Keqin

    2015-10-01

    To introduce a new technique that combines laparoscopic and vaginal cervicovaginal reconstruction using split thickness skin graft in patients with congenital atresia of the cervix. Video article introducing a new surgical technique. University hospital. A 16-year-old patient with congenital cervical atresia, vaginal dysgenesis, and ovarian endometrial cyst. An original technique of combined laparoscopic and vaginal cervicovaginal reconstruction using split thickness skin graft for cervicovaginal reconstruction. A midline incision at the vaginal introitus was made, and a 9-cm canal was made between the bladder and the rectum using sharp and blunt dissection along the anatomic vaginal route, with the aid of laparoscopy to ensure correct orientation. A 14 × 12 cm split thickness skin graft was harvested from the right lateral thigh. By laparoscopy, the level of the lowest pole of the uterine cavity was exposed and the cervix was incised by shape dissection. The proximal segment of the harvested skin to the lower uterine segment was secured, and the distal segment was sutured with the upper margin of vulva vaginally. Surgical technique reports in anonymous patients are exempted from ethical approval by the Institutional Review Board. The patient gave consent to use the video in the article. The procedure was successfully completed. Since February 2013, our experiences of combined laparoscopic and vaginal cervicovaginal reconstruction using split thickness skin graft in 10 patients with congenital atresia of cervix were positive, with successful results and without complications or cervical, or vaginal stenosis. Our technique is feasible and safe for congenital atresia of cervix, with successful results and without complications or cervical or vaginal stenosis. Copyright © 2015 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  19. A high order semi-Lagrangian discontinuous Galerkin method for Vlasov-Poisson simulations without operator splitting

    NASA Astrophysics Data System (ADS)

    Cai, Xiaofeng; Guo, Wei; Qiu, Jing-Mei

    2018-02-01

    In this paper, we develop a high order semi-Lagrangian (SL) discontinuous Galerkin (DG) method for nonlinear Vlasov-Poisson (VP) simulations without operator splitting. In particular, we combine two recently developed novel techniques: one is the high order non-splitting SLDG transport method (Cai et al. (2017) [4]), and the other is the high order characteristics tracing technique proposed in Qiu and Russo (2017) [29]. The proposed method with up to third order accuracy in both space and time is locally mass conservative, free of splitting error, positivity-preserving, stable and robust for large time stepping size. The SLDG VP solver is applied to classic benchmark test problems such as Landau damping and two-stream instabilities for VP simulations. Efficiency and effectiveness of the proposed scheme is extensively tested. Tremendous CPU savings are shown by comparisons between the proposed SL DG scheme and the classical Runge-Kutta DG method.

  20. Assisted extraction of the energy level spacings and lever arms in direct current bias measurements of one-dimensional quantum wires, using an image recognition routine

    NASA Astrophysics Data System (ADS)

    Lesage, A. A. J.; Smith, L. W.; Al-Taie, H.; See, P.; Griffiths, J. P.; Farrer, I.; Jones, G. A. C.; Ritchie, D. A.; Kelly, M. J.; Smith, C. G.

    2015-01-01

    A multiplexer technique is used to individually measure an array of 256 split gates on a single GaAs/AlGaAs heterostructure. This results in the generation of large volumes of data, which requires the development of automated data analysis routines. An algorithm is developed to find the spacing between discrete energy levels, which form due to transverse confinement from the split gate. The lever arm, which relates split gate voltage to energy, is also found from the measured data. This reduces the time spent on the analysis. Comparison with estimates obtained visually shows that the algorithm returns reliable results for subband spacing of split gates measured at 1.4 K. The routine is also used to assess direct current bias spectroscopy measurements at lower temperatures (50 mK). This technique is versatile and can be extended to other types of measurements. For example, it is used to extract the magnetic field at which Zeeman-split 1D subbands cross one another.

  1. Creating ensembles of oblique decision trees with evolutionary algorithms and sampling

    DOEpatents

    Cantu-Paz, Erick [Oakland, CA; Kamath, Chandrika [Tracy, CA

    2006-06-13

    A decision tree system that is part of a parallel object-oriented pattern recognition system, which in turn is part of an object oriented data mining system. A decision tree process includes the step of reading the data. If necessary, the data is sorted. A potential split of the data is evaluated according to some criterion. An initial split of the data is determined. The final split of the data is determined using evolutionary algorithms and statistical sampling techniques. The data is split. Multiple decision trees are combined in ensembles.

  2. Field by field hybrid upwind splitting methods

    NASA Technical Reports Server (NTRS)

    Coquel, Frederic; Liou, Meng-Sing

    1993-01-01

    A new and general approach to upwind splitting is presented. The design principle combines the robustness of flux vector splitting schemes in the capture of nonlinear waves and the accuracy of some flux difference splitting schemes in the resolution of linear waves. The new schemes are derived following a general hybridization technique performed directly at the basic level of the field by field decomposition involved in FDS methods. The scheme does not use a spatial switch to be tuned up according to the local smoothness of the approximate solution.

  3. "Split Cast Mounting: Review and New Technique".

    PubMed

    Gundawar, S M; Pande, Neelam A; Jaiswal, Priti; Radke, U M

    2014-12-01

    For the fabrication of a prosthesis, the Prosthodontist meticulously performs all the steps. The laboratory technician then make every effort/strives to perform the remaining lab procedures. However when the processed dentures are remounted on the articulator, some changes are seen. These changes may be divided into two categories: Pre-insertion and post-insertion changes, which deal with the physical properties of the materials involved (Parker, J Prosthet Dent 31:335-342, 1974). Split cast mounting is the method of mounting casts on the articulator. It is essentially a maxillary cast constructed in two parts with a horizontal division. The procedure allows for the verification of the accuracy of the initial mounting and the ease of removal and replacement of the cast. This provides a precise means of correcting the changes in occlusion occurring as a result of the processing technique (Nogueira et al., J Prosthet Dent 91:386-388, 2004). Instability of the split mounting has always been a problem to the Prosthodontist thereby limiting its use. There are various materials mentioned in the literature. The new technique by using Dowel pins and twill thread is very easy, cheaper and simple way to stabilize the split mounting. It is useful and easy in day to day laboratory procedures. The article presents different methods of split cast mounting and the new procedure using easily available materials in prosthetic laboratory.

  4. Anisotropic in-plane spin splitting in an asymmetric (001) GaAs/AlGaAs quantum well

    PubMed Central

    2011-01-01

    The in-plane spin splitting of conduction-band electron has been investigated in an asymmetric (001) GaAs/AlxGa1-xAs quantum well by time-resolved Kerr rotation technique under a transverse magnetic field. The distinctive anisotropy of the spin splitting was observed while the temperature is below approximately 200 K. This anisotropy emerges from the combined effect of Dresselhaus spin-orbit coupling plus asymmetric potential gradients. We also exploit the temperature dependence of spin-splitting energy. Both the anisotropy of spin splitting and the in-plane effective g-factor decrease with increasing temperature. PACS: 78.47.jm, 71.70.Ej, 75.75.+a, 72.25.Fe, PMID:21888636

  5. The Linearized Bregman Method for Frugal Full-waveform Inversion with Compressive Sensing and Sparsity-promoting

    NASA Astrophysics Data System (ADS)

    Chai, Xintao; Tang, Genyang; Peng, Ronghua; Liu, Shaoyong

    2018-03-01

    Full-waveform inversion (FWI) reconstructs the subsurface properties from acquired seismic data via minimization of the misfit between observed and simulated data. However, FWI suffers from considerable computational costs resulting from the numerical solution of the wave equation for each source at each iteration. To reduce the computational burden, constructing supershots by combining several sources (aka source encoding) allows mitigation of the number of simulations at each iteration, but it gives rise to crosstalk artifacts because of interference between the individual sources of the supershot. A modified Gauss-Newton FWI (MGNFWI) approach showed that as long as the difference between the initial and true models permits a sparse representation, the ℓ _1-norm constrained model updates suppress subsampling-related artifacts. However, the spectral-projected gradient ℓ _1 (SPGℓ _1) algorithm employed by MGNFWI is rather complicated that makes its implementation difficult. To facilitate realistic applications, we adapt a linearized Bregman (LB) method to sparsity-promoting FWI (SPFWI) because of the efficiency and simplicity of LB in the framework of ℓ _1-norm constrained optimization problem and compressive sensing. Numerical experiments performed with the BP Salt model, the Marmousi model and the BG Compass model verify the following points. The FWI result with LB solving ℓ _1-norm sparsity-promoting problem for the model update outperforms that generated by solving ℓ _2-norm problem in terms of crosstalk elimination and high-fidelity results. The simpler LB method performs comparably and even superiorly to the complicated SPGℓ _1 method in terms of computational efficiency and model quality, making the LB method a viable alternative for realistic implementations of SPFWI.

  6. Split Node and Stress Glut Methods for Dynamic Rupture Simulations in Finite Elements.

    NASA Astrophysics Data System (ADS)

    Ramirez-Guzman, L.; Bielak, J.

    2008-12-01

    I present two numerical techniques to solve the Dynamic problem. I revisit and modify the Split Node approach and introduce a Stress Glut type Method. Both algorithms are implemented using a iso/sub- parametric FEM solver. In the first case, I discuss the formulation and perform an analysis of convergence for different orders of approximation for the acoustic case. I describe the algorithm of the second methodology as well as the assumptions made. The key to the new technique is to have an accurate representation of the traction. Thus, I devote part of the discussion to analyze the tractions for a simple example. The sensitivity of the method is tested by comparing against Split Node solutions.

  7. Bad splits in bilateral sagittal split osteotomy: systematic review of fracture patterns.

    PubMed

    Steenen, S A; Becking, A G

    2016-07-01

    An unfavourable and unanticipated pattern of the mandibular sagittal split osteotomy is generally referred to as a 'bad split'. Few restorative techniques to manage the situation have been described. In this article, a classification of reported bad split pattern types is proposed and appropriate salvage procedures to manage the different types of undesired fracture are presented. A systematic review was undertaken, yielding a total of 33 studies published between 1971 and 2015. These reported a total of 458 cases of bad splits among 19,527 sagittal ramus osteotomies in 10,271 patients. The total reported incidence of bad split was 2.3% of sagittal splits. The most frequently encountered were buccal plate fractures of the proximal segment (types 1A-F) and lingual fractures of the distal segment (types 2A and 2B). Coronoid fractures (type 3) and condylar neck fractures (type 4) have seldom been reported. The various types of bad split may require different salvage approaches. Copyright © 2016 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  8. Creating ensembles of decision trees through sampling

    DOEpatents

    Kamath, Chandrika; Cantu-Paz, Erick

    2005-08-30

    A system for decision tree ensembles that includes a module to read the data, a module to sort the data, a module to evaluate a potential split of the data according to some criterion using a random sample of the data, a module to split the data, and a module to combine multiple decision trees in ensembles. The decision tree method is based on statistical sampling techniques and includes the steps of reading the data; sorting the data; evaluating a potential split according to some criterion using a random sample of the data, splitting the data, and combining multiple decision trees in ensembles.

  9. Continuous state-space representation of a bucket-type rainfall-runoff model: a case study with the GR4 model using state-space GR4 (version 1.0)

    NASA Astrophysics Data System (ADS)

    Santos, Léonard; Thirel, Guillaume; Perrin, Charles

    2018-04-01

    In many conceptual rainfall-runoff models, the water balance differential equations are not explicitly formulated. These differential equations are solved sequentially by splitting the equations into terms that can be solved analytically with a technique called operator splitting. As a result, only the solutions of the split equations are used to present the different models. This article provides a methodology to make the governing water balance equations of a bucket-type rainfall-runoff model explicit and to solve them continuously. This is done by setting up a comprehensive state-space representation of the model. By representing it in this way, the operator splitting, which makes the structural analysis of the model more complex, could be removed. In this state-space representation, the lag functions (unit hydrographs), which are frequent in rainfall-runoff models and make the resolution of the representation difficult, are first replaced by a so-called Nash cascade and then solved with a robust numerical integration technique. To illustrate this methodology, the GR4J model is taken as an example. The substitution of the unit hydrographs with a Nash cascade, even if it modifies the model behaviour when solved using operator splitting, does not modify it when the state-space representation is solved using an implicit integration technique. Indeed, the flow time series simulated by the new representation of the model are very similar to those simulated by the classic model. The use of a robust numerical technique that approximates a continuous-time model also improves the lag parameter consistency across time steps and provides a more time-consistent model with time-independent parameters.

  10. Segmenting overlapping nano-objects in atomic force microscopy image

    NASA Astrophysics Data System (ADS)

    Wang, Qian; Han, Yuexing; Li, Qing; Wang, Bing; Konagaya, Akihiko

    2018-01-01

    Recently, techniques for nanoparticles have rapidly been developed for various fields, such as material science, medical, and biology. In particular, methods of image processing have widely been used to automatically analyze nanoparticles. A technique to automatically segment overlapping nanoparticles with image processing and machine learning is proposed. Here, two tasks are necessary: elimination of image noises and action of the overlapping shapes. For the first task, mean square error and the seed fill algorithm are adopted to remove noises and improve the quality of the original image. For the second task, four steps are needed to segment the overlapping nanoparticles. First, possibility split lines are obtained by connecting the high curvature pixels on the contours. Second, the candidate split lines are classified with a machine learning algorithm. Third, the overlapping regions are detected with the method of density-based spatial clustering of applications with noise (DBSCAN). Finally, the best split lines are selected with a constrained minimum value. We give some experimental examples and compare our technique with two other methods. The results can show the effectiveness of the proposed technique.

  11. Bad split during bilateral sagittal split osteotomy of the mandible with separators: a retrospective study of 427 patients.

    PubMed

    Mensink, Gertjan; Verweij, Jop P; Frank, Michael D; Eelco Bergsma, J; Richard van Merkesteyn, J P

    2013-09-01

    An unfavourable fracture, known as a bad split, is a common operative complication in bilateral sagittal split osteotomy (BSSO). The reported incidence ranges from 0.5 to 5.5%/site. Since 1994 we have used sagittal splitters and separators instead of chisels for BSSO in our clinic in an attempt to prevent postoperative hypoaesthesia. Theoretically an increased percentage of bad splits could be expected with this technique. In this retrospective study we aimed to find out the incidence of bad splits associated with BSSO done with splitters and separators. We also assessed the risk factors for bad splits. The study group comprised 427 consecutive patients among whom the incidence of bad splits was 2.0%/site, which is well within the reported range. The only predictive factor for a bad split was the removal of third molars at the same time as BSSO. There was no significant association between bad splits and age, sex, class of occlusion, or the experience of the surgeon. We think that doing a BSSO with splitters and separators instead of chisels does not increase the risk of a bad split, and is therefore safe with predictable results. Copyright © 2012 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  12. Influence of core design, production technique, and material selection on fracture behavior of yttria-stabilized tetragonal zirconia polycrystal fixed dental prostheses produced using different multilayer techniques: split-file, over-pressing, and manually built-up veneers.

    PubMed

    Mahmood, Deyar Jallal Hadi; Linderoth, Ewa H; Wennerberg, Ann; Vult Von Steyern, Per

    2016-01-01

    To investigate and compare the fracture strength and fracture mode in eleven groups of currently, the most commonly used multilayer three-unit all-ceramic yttria-stabilized tetragonal zirconia polycrystal (Y-TZP) fixed dental prostheses (FDPs) with respect to the choice of core material, veneering material area, manufacturing technique, design of connectors, and radii of curvature of FDP cores. A total of 110 three-unit Y-TZP FDP cores with one intermediate pontic were made. The FDP cores in groups 1-7 were made with a split-file design, veneered with manually built-up porcelain, computer-aided design-on veneers, and over-pressed veneers. Groups 8-11 consisted of FDPs with a state-of-the-art design, veneered with manually built-up porcelain. All the FDP cores were subjected to simulated aging and finally loaded to fracture. There was a significant difference (P<0.05) between the core designs, but not between the different types of Y-TZP materials. The split-file designs with VITABLOCS(®) (1,806±165 N) and e.max(®) ZirPress (1,854±115 N) and the state-of-the-art design with VITA VM(®) 9 (1,849±150 N) demonstrated the highest mean fracture values. The shape of a split-file designed all-ceramic reconstruction calls for a different dimension protocol, compared to traditionally shaped ones, as the split-file design leads to sharp approximal indentations acting as fractural impressions, thus decreasing the overall strength. The design of a framework is a crucial factor for the load bearing capacity of an all-ceramic FDP. The state-of-the-art design is preferable since the split-file designed cores call for a cross-sectional connector area at least 42% larger, to have the same load bearing capacity as the state-of-the-art designed cores. All veneering materials and techniques tested in the study, split-file, over-press, built-up porcelains, and glass-ceramics are, with a great safety margin, sufficient for clinical use both anteriorly and posteriorly. Analysis of the fracture pattern shows differences between the milled veneers and over-pressed or built-up veneers, where the milled ones show numerically more veneer cracks and the other groups only show complete connector fractures.

  13. Pharmaceutical counselling about different types of tablet-splitting methods based on the results of weighing tests and mechanical development of splitting devices.

    PubMed

    Somogyi, O; Meskó, A; Csorba, L; Szabó, P; Zelkó, R

    2017-08-30

    The division of tablets and adequate methods of splitting them are a complex problem in all sectors of health care. Although tablet-splitting is often required, this procedure can be difficult for patients. Four tablets were investigated with different external features (shape, score-line, film-coat and size). The influencing effect of these features and the splitting methods was investigated according to the precision and "weight loss" of splitting techniques. All four types of tablets were halved by four methods: by hand, with a kitchen knife, with an original manufactured splitting device and with a modified tablet splitter based on a self-developed mechanical model. The mechanical parameters (harness and friability) of the products were measured during the study. The "weight loss" and precision of splitting methods were determined and compared by statistical analysis. On the basis of the results, the external features (geometry), the mechanical parameters of tablets and the mechanical structure of splitting devices can influence the "weight loss" and precision of tablet-splitting. Accordingly, a new decision-making scheme was developed for the selection of splitting methods. In addition, the skills of patients and the specialties of therapy should be considered so that pharmaceutical counselling can be more effective regarding tablet-splitting. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Rapid orthodontic treatment after the ridge-splitting technique--a combined surgical-orthodontic approach for implant site development: case report.

    PubMed

    Amato, Francesco; Mirabella, A Davide; Borlizzi, Diego

    2012-08-01

    This article presents a clinical case of bilateral partial edentulism in the posterior mandible with severe horizontal and moderate vertical bone atrophy. A new technique using rapid orthodontics after ridge splitting is presented. The split-crest technique was carried out using piezosurgical instruments in the first molar and second premolar areas to widen the bone crest and open a channel for tooth movement. Immediately after, orthodontic appliances were used to move the first premolars distally and the second molars mesially into the surgical site. The rationale was to facilitate and accelerate orthodontic movement of the teeth, which is otherwise difficult in a cortical knife-edged ridge. The bone defect was filled with the alveolar bone of the adjacent teeth that were moved into the surgically opened path. Adequate bone volume for implant placement was generated in the first premolar area. Implants were then inserted, and the patient was rehabilitated.

  15. A Split-Mouth Design Comparison for Lateral and Crestal Sinus Lift Techniques with Dental Implants Placements: Short Communication.

    PubMed

    Al-Almaie, Saad; Kavarodi, Abdul Majeed; Alorf, Ali; Alzahrani, Saeed

    2017-01-01

    The objective of this study is to compare and evaluate the effectiveness of implant placement and patient appraisal for two sinus lift techniques using both crestal and lateral techniques for bilateral sinus left in a split-mouth design. All implants were successfully osseointegrated without any clinical complications or peri-implant radiolucency during the follow-up period of maximum 3 years. In terms of outcomes postoperative vertigo showed to be a major concern with the crestal approach, this approach is preferred over the lateral technique because of the reduced time required for the procedure and because it is less invasive. Most patients preferred the crestal approach over the lateral approach due to the delay in implant placement.

  16. On split regular BiHom-Lie superalgebras

    NASA Astrophysics Data System (ADS)

    Zhang, Jian; Chen, Liangyun; Zhang, Chiping

    2018-06-01

    We introduce the class of split regular BiHom-Lie superalgebras as the natural extension of the one of split Hom-Lie superalgebras and the one of split Lie superalgebras. By developing techniques of connections of roots for this kind of algebras, we show that such a split regular BiHom-Lie superalgebra L is of the form L = U +∑ [ α ] ∈ Λ / ∼I[α] with U a subspace of the Abelian (graded) subalgebra H and any I[α], a well described (graded) ideal of L, satisfying [I[α] ,I[β] ] = 0 if [ α ] ≠ [ β ] . Under certain conditions, in the case of L being of maximal length, the simplicity of the algebra is characterized and it is shown that L is the direct sum of the family of its simple (graded) ideals.

  17. Mesoscale, Radiometrically Referenced, Multi-Temporal Hyperspectral Data for Co2 Leak Detection by Locating Spatial Variation of Biophysically Relevant Parameters

    NASA Astrophysics Data System (ADS)

    McCann, Cooper Patrick

    Low-cost flight-based hyperspectral imaging systems have the potential to provide valuable information for ecosystem and environmental studies as well as aide in land management and land health monitoring. This thesis describes (1) a bootstrap method of producing mesoscale, radiometrically-referenced hyperspectral data using the Landsat surface reflectance (LaSRC) data product as a reference target, (2) biophysically relevant basis functions to model the reflectance spectra, (3) an unsupervised classification technique based on natural histogram splitting of these biophysically relevant parameters, and (4) local and multi-temporal anomaly detection. The bootstrap method extends standard processing techniques to remove uneven illumination conditions between flight passes, allowing the creation of radiometrically self-consistent data. Through selective spectral and spatial resampling, LaSRC data is used as a radiometric reference target. Advantages of the bootstrap method include the need for minimal site access, no ancillary instrumentation, and automated data processing. Data from a flight on 06/02/2016 is compared with concurrently collected ground based reflectance spectra as a means of validation achieving an average error of 2.74%. Fitting reflectance spectra using basis functions, based on biophysically relevant spectral features, allows both noise and data reductions while shifting information from spectral bands to biophysical features. Histogram splitting is used to determine a clustering based on natural splittings of these fit parameters. The Indian Pines reference data enabled comparisons of the efficacy of this technique to established techniques. The splitting technique is shown to be an improvement over the ISODATA clustering technique with an overall accuracy of 34.3/19.0% before merging and 40.9/39.2% after merging. This improvement is also seen as an improvement of kappa before/after merging of 24.8/30.5 for the histogram splitting technique compared to 15.8/28.5 for ISODATA. Three hyperspectral flights over the Kevin Dome area, covering 1843 ha, acquired 06/21/2014, 06/24/2015 and 06/26/2016 are examined with different methods of anomaly detection. Detection of anomalies within a single data set is examined to determine, on a local scale, areas that are significantly different from the surrounding area. Additionally, the detection and identification of persistent anomalies and non-persistent anomalies was investigated across multiple data sets.

  18. Cranioplasty Using a Modified Split Calvarial Graft Technique in Cleidocranial Dysplasia

    PubMed Central

    Jung, Young Taek; Cho, Jae Ik

    2015-01-01

    Cleidocranial dysplasia is a well-documented rare autosomal dominant skeletal dysplasia characterized by hypoplastic/aplastic clavicles, brachycephalic skull, patent sutures and fontanelles, midface hypoplasia, and abnormalities of dentition. Patients with cleidocranial dysplasia often complain about undesirable esthetic appearance of their forehead and skull. Notwithstanding many studies of molecular, genetics and skeletal abnormalities of this congenial disorder, there have been very few written reports of cranioplasty involving cleidocranial dysplasia. Thus, we report a rare case of successful cranioplasty using a modified split calvarial graft technique in patient with cleidocranial dysplasia. PMID:26279819

  19. A Novel Technique for Split-Thickness Skin Donor Site Pain Control: Subcutaneous Catheters for Continuous Local Anesthetic Infusion

    DTIC Science & Technology

    2012-01-01

    the new: a novel approach to treating pain associated with rib fractures . World J Surg 2010;34:2359–62. 3. Wheatley GH III, Rosenbaum DH, Paul MC, et...has been described after laparotomy, tho- racotomy, inguinal hernia repair, and rib fractures .2–4 We describe our experience at the U.S. Army Insti...JAN 2012 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE A novel technique for split-thickness skin donor site pain control

  20. Clinical Comparison of At-Home and In-Office Dental Bleaching Procedures: A Randomized Trial of a Split-Mouth Design.

    PubMed

    Machado, Lucas Silveira; Anchieta, Rodolfo Bruniera; dos Santos, Paulo Henrique; Briso, André Luiz; Tovar, Nick; Janal, Malvin N; Coelho, Paulo Guilherme; Sundfeld, Renato Herman

    2016-01-01

    The objective of this split-mouth clinical study was to compare a combination of in-office and at-home dental bleaching with at-home bleaching alone. Two applications of in-office bleaching were performed, with one appointment per week, using 38% hydrogen peroxide. At-home bleaching was performed with or without in-office bleaching using 10% carbamide peroxide in a custom-made tray every night for 2 weeks. The factor studied was the bleaching technique on two levels: Technique 1 (in-office bleaching combined with home bleaching) and Technique 2 (home bleaching only). The response variables were color change, dental sensitivity, morphology, and surface roughness. The maxillary right and left hemiarches of the participants were submitted to in-office placebo treatment and in-office bleaching, respectively (Phase 1), and at-home bleaching (Phase 2) treatment was performed on both hemiarches, characterizing a split-mouth design. Enamel surface changes and roughness were analyzed with scanning electron microscopy and optical interferometry using epoxy replicas. No statistically significant differences were observed between the bleaching techniques for either the visual or the digital analyses. There was a significant difference in dental sensitivity when both dental bleaching techniques were used, with in-office bleaching producing the highest levels of dental sensitivity after the baseline. Microscopic analysis of the morphology and roughness of the enamel surface showed no significant changes between the bleaching techniques. The two techniques produced similar results in color change, and the combination technique produced the highest levels of sensitivity. Neither technique promoted changes in morphology or surface roughness of enamel.

  1. A Comparison among Worker Types Using a Composites Approach and Median Splits

    ERIC Educational Resources Information Center

    Aziz, Shahnaz; Wuensch, Karl L.; Brandon, Howard R.

    2010-01-01

    The current study examined Spence and Robbins' (1992) worker types in terms of correlates of workaholism (e.g., work-life imbalance, obsessive-compulsive behavior). A survey was administered to professionals, who were then classified into different worker types following the traditional median-split technique. The data were also analyzed with…

  2. Fabrication of cooled radial turbine rotor

    NASA Technical Reports Server (NTRS)

    Hammer, A. N.; Aigret, G. G.; Psichogios, T. P.; Rodgers, C.

    1986-01-01

    A design and fabrication program was conducted to evaluate a unique concept for constructing a cooled, high temperature radial turbine rotor. This concept, called split blade fabrication was developed as an alternative to internal ceramic coring. In this technique, the internal cooling cavity is created without flow dividers or any other detail by a solid (and therefore stronger) ceramic plate which can be more firmly anchored within the casting shell mold than can conventional detailed ceramic cores. Casting is conducted in the conventional manner, except that the finished product, instead of having finished internal cooling passages, is now a split blade. The internal details of the blade are created separately together with a carrier sheet. The inserts are superalloy. Both are produced by essentially the same software such that they are a net fit. The carrier assemblies are loaded into the split blade and the edges sealed by welding. The entire wheel is Hot Isostatic Pressed (HIPed), braze bonding the internal details to the inside of the blades. During this program, two wheels were successfully produced by the split blade fabrication technique.

  3. Split-shot sinker facilitates seton treatment of anal fistulae.

    PubMed

    Awad, M L; Sell, H W; Stahlfeld, K R

    2009-06-01

    The cutting seton is an inexpensive and effective method of treating high complex perianal fistulae. Following placement of the seton, advancement through the external sphincter muscles requires progressive tightening of the seton. The requirement for maintaining the appropriate tension and onset of perianal pressure necrosis are problems frequently encountered using this technique. Using a 3-0 polypropylene suture, a red-rubber catheter, and a nontoxic tin split-shot sinker, we minimized or eliminated these problems. We initially used this technique in one patient with satisfactory results. This technique is technically easy, safe, inexpensive, and efficient, and we are using it in all patients with high perianal fistulae who require a seton.

  4. A Split-Mouth Design Comparison for Lateral and Crestal Sinus Lift Techniques with Dental Implants Placements: Short Communication

    PubMed Central

    Al-Almaie, Saad; Kavarodi, Abdul Majeed; Alorf, Ali; Alzahrani, Saeed

    2017-01-01

    Objective: The objective of this study is to compare and evaluate the effectiveness of implant placement and patient appraisal for two sinus lift techniques using both crestal and lateral techniques for bilateral sinus left in a split-mouth design. Introduction: All implants were successfully osseointegrated without any clinical complications or peri-implant radiolucency during the follow-up period of maximum 3 years. Methods: In terms of outcomes postoperative vertigo showed to be a major concern with the crestal approach, this approach is preferred over the lateral technique because of the reduced time required for the procedure and because it is less invasive. Results: Most patients preferred the crestal approach over the lateral approach due to the delay in implant placement. PMID:29290838

  5. Carotid dual-energy CT angiography: Evaluation of low keV calculated monoenergetic datasets by means of a frequency-split approach for noise reduction at low keV levels.

    PubMed

    Riffel, Philipp; Haubenreisser, Holger; Meyer, Mathias; Sudarski, Sonja; Morelli, John N; Schmidt, Bernhard; Schoenberg, Stefan O; Henzler, Thomas

    2016-04-01

    Calculated monoenergetic ultra-low keV datasets did not lead to improved contrast-to-noise ratio (CNR) due to the dramatic increase in image noise. The aim of the present study was to evaluate the objective image quality of ultra-low keV monoenergetic images (MEIs) calculated from carotid DECT angiography data with a new monoenergetic imaging algorithm using a frequency-split technique. 20 patients (12 male; mean age 53±17 years) were retrospectively analyzed. MEIs from 40 to 120 keV were reconstructed using the monoenergetic split frequency approach (MFSA). Additionally MEIs were reconstructed for 40 and 50 keV using a conventional monoenergetic (CM) software application. Signal intensity, noise, signal-to-noise ratio (SNR) and CNR were assessed in the basilar, common, internal carotid arteries. Ultra-low keV MEIs at 40 keV and 50 keV demonstrated highest vessel attenuation, significantly greater than those of the polyenergetic images (PEI) (all p-values <0.05). The highest SNR level and CNR level was found at 40 keV and 50 keV (all p-values <0.05). MEIs with MFSA showed significantly lower noise levels than those processed with CM (all p-values <0.05) and no significant differences in vessel attenuation (p>0.05). Thus MEIs with MFSA showed significantly higher SNR and CNR compared to MEIs with CM. Combining the lower spatial frequency stack for contrast at low keV levels with the high spatial frequency stack for noise at high keV levels (frequency-split technique) leads to improved image quality of ultra-low keV monoenergetic DECT datasets when compared to previous monoenergetic reconstruction techniques without the frequency-split technique. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  6. A Split Forcing Technique to Reduce Log-layer Mismatch in Wall-modeled Turbulent Channel Flows

    NASA Astrophysics Data System (ADS)

    Deleon, Rey; Senocak, Inanc

    2016-11-01

    The conventional approach to sustain a flow field in a periodic channel flow seems to be the culprit behind the log-law mismatch problem that has been reported in many studies hybridizing Reynolds-averaged Navier-Stokes (RANS) and large-eddy simulation (LES) techniques, commonly referred to as hybrid RANS-LES. To address this issue, we propose a split-forcing approach that relies only on the conservation of mass principle. We adopt a basic hybrid RANS-LES technique on a coarse mesh with wall-stress boundary conditions to simulate turbulent channel flows at friction Reynolds numbers of 2000 and 5200 and demonstrate good agreement with benchmark data. We also report a duality in velocity scale that is a specific consequence of the split forcing framework applied to hybrid RANS-LES. The first scale is the friction velocity derived from the wall shear stress. The second scale arises in the core LES region, a value different than at the wall. Second-order turbulence statistics agree well with the benchmark data when normalized by the core friction velocity, whereas the friction velocity at the wall remains the appropriate scale for the mean velocity profile. Based on our findings, we suggest reevaluating more sophisticated hybrid RANS-LES approaches within the split-forcing framework. Work funded by National Science Foundation under Grant No. 1056110 and 1229709. First author acknowledges the University of Idaho President's Doctoral Scholars Award.

  7. Piezosurgery for the Lingual Split Technique in Lingual Positioned Impacted Mandibular Third Molar Removal: A Retrospective Study.

    PubMed

    Ge, Jing; Yang, Chi; Zheng, Jiawei; Qian, Wentao

    2016-03-01

    The aim of this study was to evaluate the effect and safety of lingual split technique using piezosurgery for the extraction of lingual positioned impacted mandibular 3rd molars with the goal of proposing a more minimally invasive choice for this common surgery.Eighty-nine consecutive patients with 110 lingual positioned impacted mandibular 3rd molars requiring extraction were performed the lingual split technique using piezosurgery. One sagittal osteotomy line and 2 transverse osteotomy line were designed for lingual and occlusal bone removal. The success rate, operative time, postoperative outcome, and major complications (including nerve injury, mandible fracture, severe hematoma or edema, and severe pyogenic infection) were documented and analyzed.All impacted mandibular 3rd molars were successfully removed (110/110). The average time of operation was 14.6 minutes (ranged from 7 to 28 minutes). One hundred and seven extraction sites (97.3%) were primary healing. Pain, mouth opening, swelling, and PoSSe scores on postoperative 7-day were 0.34 ± 0.63, 3.88 ± 0.66(cm), 2.4 ± 0.2(cm), and 23.7 ± 5.9, respectively. There were 6 cases (5.5%) had lingual nerve disturbance and 3 cases (2.7%) developed inferior alveolar nerve impairment, and achieved full recovery within 2 months by neurotrophic drug treatment.Our study suggested piezosurgery for lingual split technique provided an effective way for the extraction of lingual positioned and deeply impacted mandibular 3rd molar.

  8. Piezosurgery for the Lingual Split Technique in Lingual Positioned Impacted Mandibular Third Molar Removal

    PubMed Central

    Ge, Jing; Yang, Chi; Zheng, Jiawei; Qian, Wentao

    2016-01-01

    Abstract The aim of this study was to evaluate the effect and safety of lingual split technique using piezosurgery for the extraction of lingual positioned impacted mandibular 3rd molars with the goal of proposing a more minimally invasive choice for this common surgery. Eighty-nine consecutive patients with 110 lingual positioned impacted mandibular 3rd molars requiring extraction were performed the lingual split technique using piezosurgery. One sagittal osteotomy line and 2 transverse osteotomy line were designed for lingual and occlusal bone removal. The success rate, operative time, postoperative outcome, and major complications (including nerve injury, mandible fracture, severe hematoma or edema, and severe pyogenic infection) were documented and analyzed. All impacted mandibular 3rd molars were successfully removed (110/110). The average time of operation was 14.6 minutes (ranged from 7 to 28 minutes). One hundred and seven extraction sites (97.3%) were primary healing. Pain, mouth opening, swelling, and PoSSe scores on postoperative 7-day were 0.34 ± 0.63, 3.88 ± 0.66(cm), 2.4 ± 0.2(cm), and 23.7 ± 5.9, respectively. There were 6 cases (5.5%) had lingual nerve disturbance and 3 cases (2.7%) developed inferior alveolar nerve impairment, and achieved full recovery within 2 months by neurotrophic drug treatment. Our study suggested piezosurgery for lingual split technique provided an effective way for the extraction of lingual positioned and deeply impacted mandibular 3rd molar. PMID:27015214

  9. Modulated-splitting-ratio fiber-optic temperature sensor

    NASA Technical Reports Server (NTRS)

    Beheim, Glenn; Anthan, Donald J.; Rys, John R.; Fritsch, Klaus; Ruppe, Walter A.

    1988-01-01

    A fiber-optic temperature sensor is described, which uses a small silicon beamsplitter whose splitting ratio varies as a function of temperature. A four-beam technique is used to measure the sensor's temperature-indicating splitting ratio. This referencing method provides a measurement that is largely independent of the transmission properties of the sensor's optical fiber link. A significant advantage of this sensor, relative to other fiber-optic sensors, is its high stability, which permits the fiber-optic components to be readily substituted, thereby simplifying the sensor's installation and maintenance.

  10. Visible-light driven nitrogen-doped petal-morphological ceria nanosheets for water splitting

    NASA Astrophysics Data System (ADS)

    Qian, Junchao; Zhang, Wenya; Wang, Yaping; Chen, Zhigang; Chen, Feng; Liu, Chengbao; Lu, Xiaowang; Li, Ping; Wang, Kaiyuan; Chen, Ailian

    2018-06-01

    Water splitting is a promising sustainable technology for solar-to-chemical energy conversion. Herein, we successfully fabricated nitrogen-doped ultrathin CeO2 nanosheets by using field poppy petals as templates, which exhibit an efficiently catalytic activity for water splitting. Abundant oxygen vacancies and substitutional N atoms were experimentally observed in the film due to its unique biomorphic texture. In view of high efficiency and long durability of the as-prepared photocatalyst, this biotemplate method may provide an alternative technique for using biomolecules to assemble 2D nanomaterials.

  11. Learning classification trees

    NASA Technical Reports Server (NTRS)

    Buntine, Wray

    1991-01-01

    Algorithms for learning classification trees have had successes in artificial intelligence and statistics over many years. How a tree learning algorithm can be derived from Bayesian decision theory is outlined. This introduces Bayesian techniques for splitting, smoothing, and tree averaging. The splitting rule turns out to be similar to Quinlan's information gain splitting rule, while smoothing and averaging replace pruning. Comparative experiments with reimplementations of a minimum encoding approach, Quinlan's C4 and Breiman et al. Cart show the full Bayesian algorithm is consistently as good, or more accurate than these other approaches though at a computational price.

  12. Small-bubble transport and splitting dynamics in a symmetric bifurcation.

    PubMed

    Qamar, Adnan; Warnez, Matthew; Valassis, Doug T; Guetzko, Megan E; Bull, Joseph L

    2017-08-01

    Simulations of small bubbles traveling through symmetric bifurcations are conducted to garner information pertinent to gas embolotherapy, a potential cancer treatment. Gas embolotherapy procedures use intra-arterial bubbles to occlude tumor blood supply. As bubbles pass through bifurcations in the blood stream nonhomogeneous splitting and undesirable bioeffects may occur. To aid development of gas embolotherapy techniques, a volume of fluid method is used to model the splitting process of gas bubbles passing through artery and arteriole bifurcations. The model reproduces the variety of splitting behaviors observed experimentally, including the bubble reversal phenomenon. Splitting homogeneity and maximum shear stress along the vessel walls is predicted over a variety of physical parameters. Small bubbles, having initial length less than twice the vessel diameter, were found unlikely to split in the presence of gravitational asymmetry. Maximum shear stresses were found to decrease exponentially with increasing Reynolds number. Vortex-induced shearing near the bifurcation is identified as a possible mechanism for endothelial cell damage.

  13. Machine learning with quantum relative entropy

    NASA Astrophysics Data System (ADS)

    Tsuda, Koji

    2009-12-01

    Density matrices are a central tool in quantum physics, but it is also used in machine learning. A positive definite matrix called kernel matrix is used to represent the similarities between examples. Positive definiteness assures that the examples are embedded in an Euclidean space. When a positive definite matrix is learned from data, one has to design an update rule that maintains the positive definiteness. Our update rule, called matrix exponentiated gradient update, is motivated by the quantum relative entropy. Notably, the relative entropy is an instance of Bregman divergences, which are asymmetric distance measures specifying theoretical properties of machine learning algorithms. Using the calculus commonly used in quantum physics, we prove an upperbound of the generalization error of online learning.

  14. End results of radiation therapy, alone and combination with 5-fluorouracil in colorectal cancers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vongtama, V.; Douglass, H.O.; Moore, R.H.

    The authors retrospectively analyzed the results of irradiation in 148 cases of primary inoperable and recurrent adenocarcinoma of the colon and rectum treated at the Department of Radiation Therapy, Roswell Park Memorial Institute between 1962 and 1970. This group includes 95 recurrences and 53 inoperable primaries. Uninterrupted radiotherapy was used in 118 cases and split-course technique in 30 cases. Eleven patients received combined radiotherapy and surgery. Seventy-eight patients received a combination of 5-fluorouracil (5-FU) and irradiation. The response rate and survival of individual groups is discussed in detail. This study indicated that perineal recurrences should receive whole pelvic irradiation inmore » addition to perineum field. Split-course technique appeared to yield a better survival than the uninterrupted course. The best 5-year survival rate (64 percent) is found in the group treated with a combination of radiation and surgery. For locally advanced, inoperable cancers, split-course technique, combined 5-FU and irradiation gave the best results, achieving longer palliation with improved quality of life and sometimes yielding cure (5-year survival). (auth)« less

  15. Ionospheric Correction of D-InSAR Using Split-Spectrum Technique and 3D Ionosphere Model in Deformation Monitoring

    NASA Astrophysics Data System (ADS)

    Chen, Y.; Guo, L.; Wu, J. J.; Chen, Q.; Song, S.

    2014-12-01

    In Differential Interferometric Synthetic Aperture Radar (D-InSAR) atmosphere effect including troposphere and ionosphere is one of the dominant sources of error in most interferograms, which greatly reduced the accuracy of deformation monitoring. In recent years tropospheric correction especially Zwd in InSAR data processing has ever got widely investigated and got efficiently suppressed. And thus we focused our study on ionospheric correction using two different methods, which are split-spectrum technique and Nequick model, one of the three dimensional electron density models. We processed Wenchuan ALOS PALSAR images, and compared InSAR surface deformation after ionospheric modification using the two approaches mentioned above with ground GPS subsidence observations to validate the effect of split-spectrum method and NeQuick model, further discussed the performance and feasibility of external data and InSAR itself during the study of the elimination of InSAR ionospheric effect.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    García, Abraham; Cotto, María; Duconge, José

    The use of hydrogen as replacement for fossil fuels, on which we depend today, is a matter of great relevance. The sustainable generation of hydrogen as fuel is relevant from an environmental and economic point of view. In this study we have explored new synthetic routes for developing new photocatalysts to be used in water splitting, for hydrogen production. Different techniques have been used to produce hydrogen, such as electrolysis, even though these processes have been found to be energetically non suitable. In this research various photocatalytic materials were presented as possible alternatives for using in water splitting processes. Characterizationmore » of the new synthesized materials has been done by using different experimental techniques including Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), surface area BET, and X-ray Diffraction (XRD). The efficiency of the synthesized photocatalysts was determined by evaluating the hydrogen evolution by the photocatalytic water splitting reaction.« less

  17. Choosing a DIVA: a comparison of emerging digital imagery vegetation analysis techniques

    USGS Publications Warehouse

    Jorgensen, Christopher F.; Stutzman, Ryan J.; Anderson, Lars C.; Decker, Suzanne E.; Powell, Larkin A.; Schacht, Walter H.; Fontaine, Joseph J.

    2013-01-01

    Question: What is the precision of five methods of measuring vegetation structure using ground-based digital imagery and processing techniques? Location: Lincoln, Nebraska, USA Methods: Vertical herbaceous cover was recorded using digital imagery techniques at two distinct locations in a mixed-grass prairie. The precision of five ground-based digital imagery vegetation analysis (DIVA) methods for measuring vegetation structure was tested using a split-split plot analysis of covariance. Variability within each DIVA technique was estimated using coefficient of variation of mean percentage cover. Results: Vertical herbaceous cover estimates differed among DIVA techniques. Additionally, environmental conditions affected the vertical vegetation obstruction estimates for certain digital imagery methods, while other techniques were more adept at handling various conditions. Overall, percentage vegetation cover values differed among techniques, but the precision of four of the five techniques was consistently high. Conclusions: DIVA procedures are sufficient for measuring various heights and densities of standing herbaceous cover. Moreover, digital imagery techniques can reduce measurement error associated with multiple observers' standing herbaceous cover estimates, allowing greater opportunity to detect patterns associated with vegetation structure.

  18. Short Lingual Osteotomy Using a Piezosurgery Ultrasonic Bone-Cutting Device During Sagittal Split Ramus Osteotomy.

    PubMed

    Kawase-Koga, Yoko; Mori, Yoshiyuki; Kanno, Yuki; Hoshi, Kazuto; Takato, Tsuyoshi

    2015-10-01

    Short lingual osteotomy is a useful method for the performance of sagittal split ramus osteotomy involving interference between the proximal and distal bone fragments when lateral differences exist in the setback distance. However, this procedure occasionally results in abnormal fracture and nerve injury; expert surgical skill is thus required. We herein describe a novel technique involving the use of an ultrasonic bone-cutting device (Piezosurgery; Mectron Medical Technology, Carasco, Italy) for vertical osteotomy posterior to the mandibular foramen. Successful short lingual osteotomy was performed using this technique with avoidance of abnormal fracture and neurovascular bundle damage.

  19. Clinical evaluation of split-crest technique with ultrasonic bone surgery for narrow ridge expansion: status of soft and hard tissues and implant success.

    PubMed

    Anitua, Eduardo; Begoña, Leire; Orive, Gorka

    2013-04-01

    The aim of this study was to evaluate the split-crest technique with ultrasonic bone surgery for implant placement in patients with narrow ridges, focusing on the status of soft and hard tissues and on implant success rate, at least 6 months after implant loading. During September 2007 and November 2008, 15 patients received 37 implants (BTI implants) with split-crest surgical procedure using ultrasonic bone surgery. Plasma rich in growth factors (PRGF®) was applied during split crest procedure to promote tissue regeneration. Implant surfaces were humidified with PRGF to accelerate osseointegration. Patients were recalled for a final clinical evaluation at least 6 months after implant loading. Clinical assessment included the status of soft and hard tissues around implants, and implants' success rate. Thirty-seven implants in 15 patients were evaluated between July 2009 and January 2010. The status of soft tissues was very good, showing adequate plaque index, bleeding index, and probing depth values. Success rate of implants at the end of follow-up (between 11 and 28 months after insertion) was 100%. Bone ridge was measured and compared at final examination showing a mean ridge expansion of 3.35 mm (SD: 0.34). Split-crest with ultrasonic bone surgery can be considered an effective and safe procedure for narrow ridge expansion. © 2011 Wiley Periodicals, Inc.

  20. Dynamic Tensile Experimental Techniques for Geomaterials: A Comprehensive Review

    NASA Astrophysics Data System (ADS)

    Heard, W.; Song, B.; Williams, B.; Martin, B.; Sparks, P.; Nie, X.

    2018-01-01

    This review article is dedicated to the Dynamic Behavior of Materials Technical Division for celebrating the 75th anniversary of the Society for Experimental Mechanics (SEM). Understanding dynamic behavior of geomaterials is critical for analyzing and solving engineering problems of various applications related to underground explosions, seismic, airblast, and penetration events. Determining the dynamic tensile response of geomaterials has been a great challenge in experiments due to the nature of relatively low tensile strength and high brittleness. Various experimental approaches have been made in the past century, especially in the most recent half century, to understand the dynamic behavior of geomaterials in tension. In this review paper, we summarized the dynamic tensile experimental techniques for geomaterials that have been developed. The major dynamic tensile experimental techniques include dynamic direct tension, dynamic split tension, and spall tension. All three of the experimental techniques are based on Hopkinson or split Hopkinson (also known as Kolsky) bar techniques and principles. Uniqueness and limitations for each experimental technique are also discussed.

  1. Dynamic Tensile Experimental Techniques for Geomaterials: A Comprehensive Review

    DOE PAGES

    Heard, W.; Song, B.; Williams, B.; ...

    2018-01-03

    Here, this review article is dedicated to the Dynamic Behavior of Materials Technical Division for celebrating the 75th anniversary of the Society for Experimental Mechanics (SEM). Understanding dynamic behavior of geomaterials is critical for analyzing and solving engineering problems of various applications related to underground explosions, seismic, airblast, and penetration events. Determining the dynamic tensile response of geomaterials has been a great challenge in experiments due to the nature of relatively low tensile strength and high brittleness. Various experimental approaches have been made in the past century, especially in the most recent half century, to understand the dynamic behavior ofmore » geomaterials in tension. In this review paper, we summarized the dynamic tensile experimental techniques for geomaterials that have been developed. The major dynamic tensile experimental techniques include dynamic direct tension, dynamic split tension, and spall tension. All three of the experimental techniques are based on Hopkinson or split Hopkinson (also known as Kolsky) bar techniques and principles. Finally, uniqueness and limitations for each experimental technique are also discussed.« less

  2. Dynamic Tensile Experimental Techniques for Geomaterials: A Comprehensive Review

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Heard, W.; Song, B.; Williams, B.

    Here, this review article is dedicated to the Dynamic Behavior of Materials Technical Division for celebrating the 75th anniversary of the Society for Experimental Mechanics (SEM). Understanding dynamic behavior of geomaterials is critical for analyzing and solving engineering problems of various applications related to underground explosions, seismic, airblast, and penetration events. Determining the dynamic tensile response of geomaterials has been a great challenge in experiments due to the nature of relatively low tensile strength and high brittleness. Various experimental approaches have been made in the past century, especially in the most recent half century, to understand the dynamic behavior ofmore » geomaterials in tension. In this review paper, we summarized the dynamic tensile experimental techniques for geomaterials that have been developed. The major dynamic tensile experimental techniques include dynamic direct tension, dynamic split tension, and spall tension. All three of the experimental techniques are based on Hopkinson or split Hopkinson (also known as Kolsky) bar techniques and principles. Finally, uniqueness and limitations for each experimental technique are also discussed.« less

  3. Split Coil Forms for Rotary Transformers

    NASA Technical Reports Server (NTRS)

    Mclyman, C. W. T.

    1982-01-01

    Split cores for rotor and stator windings of rotary transformer mounted around their respective coils (which are in bobbins) and cemented together. This arrangement simplifies winding of stator coil to go in a slot in inner diameter of stator coil. One practical application of rotary transformers fabricated according to this technique is for centrifuges, in which conventional sliprings are of uncertain reliability.

  4. Modified Y-splitting Procedure for the Treatment of Duane Retraction Syndrome.

    PubMed

    Altıntaş, Ayşe Gül; Arifoğlu, Hasan Basri; Köklü, Şükrü Gültekin

    2015-08-01

    To present the outcomes of modified lateral rectus Y-splitting combined with either unilateral or bilateral horizontal rectus recession in Duane Retraction Syndrome (DRS) with significant upshoot or downshoot. A total of 12 patients including 10 patients with Type I DRS and 2 with Type III DRS underwent modified Y-splitting surgery. Amount of additional recessions varied with the degree of preoperative deviation by intraoperative adjustable suture technique. Preoperatively 3 patients had esotropia (ET), 6 had exotropia (XT), and 3 patients had orthotropia. The mean preoperative deviation was 19.3 prism diopters (PD) (range, 18-20 PD) in ET patients and 19.2 PD (range, 16-20 PD) in XT patients. Postoperatively, all patients had significant correction in horizontal deviation and aligned within 4 PD of orthotropia, and no patients exhibited abnormal head posture. Co-contraction and globe retraction were markedly reduced and abnormal ocular vertical movement disappeared or significantly decreased in all cases. No patients experienced recurrence of ocular motility disorders in the mean 26-month (range, 13-66 months) follow-up period. Modified Y-splitting surgery combined with co-contracting horizontal muscle recession technique seems to be a safe and effective treatment in DRS.

  5. On the impact bending test technique for high-strength pipe steels

    NASA Astrophysics Data System (ADS)

    Arsenkin, A. M.; Odesskii, P. D.; Shabalov, I. P.; Likhachev, M. V.

    2015-10-01

    It is shown that the impact toughness (KCV-40 = 250 J/cm2) accepted for pipe steels of strength class K65 (σy ≥ 550 MPa) intended for large-diameter gas line pipes is ineffective to classify steels in fracture strength. The results obtained upon testing of specimens with a fatigue crack and additional sharp lateral grooves seem to be more effective. In energy consumption, a macrorelief with splits is found to be intermediate between ductile fracture and crystalline brittle fracture. A split formation mechanism is considered and a scheme is proposed for split formation.

  6. 3D geometric split-merge segmentation of brain MRI datasets.

    PubMed

    Marras, Ioannis; Nikolaidis, Nikolaos; Pitas, Ioannis

    2014-05-01

    In this paper, a novel method for MRI volume segmentation based on region adaptive splitting and merging is proposed. The method, called Adaptive Geometric Split Merge (AGSM) segmentation, aims at finding complex geometrical shapes that consist of homogeneous geometrical 3D regions. In each volume splitting step, several splitting strategies are examined and the most appropriate is activated. A way to find the maximal homogeneity axis of the volume is also introduced. Along this axis, the volume splitting technique divides the entire volume in a number of large homogeneous 3D regions, while at the same time, it defines more clearly small homogeneous regions within the volume in such a way that they have greater probabilities of survival at the subsequent merging step. Region merging criteria are proposed to this end. The presented segmentation method has been applied to brain MRI medical datasets to provide segmentation results when each voxel is composed of one tissue type (hard segmentation). The volume splitting procedure does not require training data, while it demonstrates improved segmentation performance in noisy brain MRI datasets, when compared to the state of the art methods. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Ten-year experience with the muscle split technique, bioabsorbable plates, and postoperative bracing for correction of pectus carinatum: the Innsbruck protocol.

    PubMed

    Del Frari, Barbara; Schwabegger, Anton H

    2011-06-01

    We reviewed further clinical experience with our approach for pectus carinatum repair: modified surgical approach of pectoralis muscle split technique, bioabsorbable plates with screws, and postoperative compressive brace. From April 2000 to February 2010, 55 patients underwent pectus carinatum repair at our department with modifications of conventional Ravitch repair. There were 14 female and 41 male patients, mean age of 19.3 years at the onset of treatment. Postoperative treatment involved fitting of a lightweight, patient-controlled chest brace. Average follow-up was 13.7 months. Patient satisfaction was excellent for 40 patients (72.7%) and good for the remaining 15 (27.3%); aesthetic appearance was excellent for 37 patients (67.3%) and good for the remaining 18 (32.7%). Postoperative evaluation was objective measurement with a thorax caliper and clinical examination. No major perioperative complications were observed. Postoperative complications were mild recurrence of deformity (n = 3) and persistent, mild, single costal cartilage protrusion (n = 2). No patient had palpable plates or screws, and there was no material breakdown. The combination of muscle split technique and absorbable osteosynthesis represents an alternative in pectus carinatum repair. The pectoralis muscle split technique allows early patient mobilization and rehabilitation. Bioabsorbable plates get completely absorbed, avoiding second operation, and chest brace provides postoperative immobilization of the anterior thoracic wall during healing and avoids development of hypertrophic scars. Our combined approach to the correction of pectus carinatum deformities yields predominantly excellent esthetic results, with low morbidity, low costs, and less invasiveness, leading to high patient satisfaction. Copyright © 2011 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

  8. Potential of human twin embryos generated by embryo splitting in assisted reproduction and research.

    PubMed

    Noli, Laila; Ogilvie, Caroline; Khalaf, Yacoub; Ilic, Dusko

    2017-03-01

    Embryo splitting or twinning has been widely used in veterinary medicine over 20 years to generate monozygotic twins with desirable genetic characteristics. The first human embryo splitting, reported in 1993, triggered fierce ethical debate on human embryo cloning. Since Dolly the sheep was born in 1997, the international community has acknowledged the complexity of the moral arguments related to this research and has expressed concerns about the potential for reproductive cloning in humans. A number of countries have formulated bans either through laws, decrees or official statements. However, in general, these laws specifically define cloning as an embryo that is generated via nuclear transfer (NT) and do not mention embryo splitting. Only the UK includes under cloning both embryo splitting and NT in the same legislation. On the contrary, the Ethics Committee of the American Society for Reproductive Medicine does not have a major ethical objection to transferring two or more artificially created embryos with the same genome with the aim of producing a single pregnancy, stating that 'since embryo splitting has the potential to improve the efficacy of IVF treatments for infertility, research to investigate the technique is ethically acceptable'. Embryo splitting has been introduced successfully to the veterinary medicine several decades ago and today is a part of standard practice. We present here an overview of embryo splitting experiments in humans and non-human primates and discuss the potential of this technology in assisted reproduction and research. A comprehensive literature search was carried out using PUBMED and Google Scholar databases to identify studies on embryo splitting in humans and non-human primates. 'Embryo splitting' and 'embryo twinning' were used as the keywords, alone or in combination with other search phrases relevant to the topics of biology of preimplantation embryos. A very limited number of studies have been conducted in humans and non-human primates. The published material, especially the studies with human embryos, is controversial. Some reports suggest that twinning technology will find clinical use in reproductive medicine in the future, whereas others conclude the opposite that human twin embryos created in vitro are unsuitable not only for clinical, but also for research, purposes. The blastomere biopsy technique of embryo splitting seems to be unsuitable for either clinical or research purposes; however, embryo bisection, a preferable method of cloning in veterinary medicine, has not yet been tested on human embryos. © The Author 2016. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  9. Automated cloud screening of AVHRR imagery using split-and-merge clustering

    NASA Technical Reports Server (NTRS)

    Gallaudet, Timothy C.; Simpson, James J.

    1991-01-01

    Previous methods to segment clouds from ocean in AVHRR imagery have shown varying degrees of success, with nighttime approaches being the most limited. An improved method of automatic image segmentation, the principal component transformation split-and-merge clustering (PCTSMC) algorithm, is presented and applied to cloud screening of both nighttime and daytime AVHRR data. The method combines spectral differencing, the principal component transformation, and split-and-merge clustering to sample objectively the natural classes in the data. This segmentation method is then augmented by supervised classification techniques to screen clouds from the imagery. Comparisons with other nighttime methods demonstrate its improved capability in this application. The sensitivity of the method to clustering parameters is presented; the results show that the method is insensitive to the split-and-merge thresholds.

  10. Using Divertor Strike Point Splitting to Study Plasma Response and Its Sensitivity to Equilibrium Uncertainties

    NASA Astrophysics Data System (ADS)

    Teklu, Abraham; Orlov, D. M.; Moyer, R. A.; Bykov, I.; Evans, T. E.; Wu, W.; Trevisan, G. L.; Lyons, B. C.; Abrams, T.; Makowski, M. A.; Lasnier, C. S.; Fenstermacher, M. E.

    2017-10-01

    Resonant magnetic perturbations (RMPs) from 3D coils have been varied to modify the splitting of the divertor strike points in DIII-D. This splitting is imaged in filtered visible and infrared emission from the divertor to determine the particle and heat flux patterns on the target plates. The observed splitting is compared to vacuum and plasma response modeling in discharges where a subset of the RMP coils were ramped to shift the divertor footprints from dominantly n = 3 to n = 2 pattern. These results will be used to determine if the plasma response model can be validated with the measured splitting. We will also study the sensitivity of the modeled splitting to details of the 2D equilibrium. This RMP ramp technique could be used in ITER to spread out the heat flux while avoiding excessive forces on the RMP coils. Work supported by U.S. DOE under the Science Undergraduate Laboratory Internship (SULI) program and DE-FC02-04ER54698, DE-FG02-07ER54917, DE-FG02-05ER54809 and DE-AC52-07NA27344.

  11. Comparative Study on the Different Testing Techniques in Tree Classification for Detecting the Learning Motivation

    NASA Astrophysics Data System (ADS)

    Juliane, C.; Arman, A. A.; Sastramihardja, H. S.; Supriana, I.

    2017-03-01

    Having motivation to learn is a successful requirement in a learning process, and needs to be maintained properly. This study aims to measure learning motivation, especially in the process of electronic learning (e-learning). Here, data mining approach was chosen as a research method. For the testing process, the accuracy comparative study on the different testing techniques was conducted, involving Cross Validation and Percentage Split. The best accuracy was generated by J48 algorithm with a percentage split technique reaching at 92.19 %. This study provided an overview on how to detect the presence of learning motivation in the context of e-learning. It is expected to be good contribution for education, and to warn the teachers for whom they have to provide motivation.

  12. Finite frequency shear wave splitting tomography: a model space search approach

    NASA Astrophysics Data System (ADS)

    Mondal, P.; Long, M. D.

    2017-12-01

    Observations of seismic anisotropy provide key constraints on past and present mantle deformation. A common method for upper mantle anisotropy is to measure shear wave splitting parameters (delay time and fast direction). However, the interpretation is not straightforward, because splitting measurements represent an integration of structure along the ray path. A tomographic approach that allows for localization of anisotropy is desirable; however, tomographic inversion for anisotropic structure is a daunting task, since 21 parameters are needed to describe general anisotropy. Such a large parameter space does not allow a straightforward application of tomographic inversion. Building on previous work on finite frequency shear wave splitting tomography, this study aims to develop a framework for SKS splitting tomography with a new parameterization of anisotropy and a model space search approach. We reparameterize the full elastic tensor, reducing the number of parameters to three (a measure of strength based on symmetry considerations for olivine, plus the dip and azimuth of the fast symmetry axis). We compute Born-approximation finite frequency sensitivity kernels relating model perturbations to splitting intensity observations. The strong dependence of the sensitivity kernels on the starting anisotropic model, and thus the strong non-linearity of the inverse problem, makes a linearized inversion infeasible. Therefore, we implement a Markov Chain Monte Carlo technique in the inversion procedure. We have performed tests with synthetic data sets to evaluate computational costs and infer the resolving power of our algorithm for synthetic models with multiple anisotropic layers. Our technique can resolve anisotropic parameters on length scales of ˜50 km for realistic station and event configurations for dense broadband experiments. We are proceeding towards applications to real data sets, with an initial focus on the High Lava Plains of Oregon.

  13. Time-dependent wave splitting and source separation

    NASA Astrophysics Data System (ADS)

    Grote, Marcus J.; Kray, Marie; Nataf, Frédéric; Assous, Franck

    2017-02-01

    Starting from classical absorbing boundary conditions, we propose a method for the separation of time-dependent scattered wave fields due to multiple sources or obstacles. In contrast to previous techniques, our method is local in space and time, deterministic, and avoids a priori assumptions on the frequency spectrum of the signal. Numerical examples in two space dimensions illustrate the usefulness of wave splitting for time-dependent scattering problems.

  14. Astronomical polarization studies at radio and infrared wavelengths. Part 1: Gravitational deflection of polarized radiation

    NASA Technical Reports Server (NTRS)

    Dennison, B. K.

    1976-01-01

    The gravitational field is probed in a search for polarization dependence in the light bending. This involves searching for a splitting of a source image into orthogonal polarizations as the radiation passes through the solar gravitational field. This search was carried out using the techniques of very long and intermediate baseline interferometry, and by seeking a relative phase delay in orthogonal polarizations of microwaves passing through the solar gravitational field. In this last technique a change in the total polarization of the Helios 1 carrier wave was sought as the spacecraft passed behind the sun. No polarization splitting was detected.

  15. In vitro study on the disinfectability of two split-septum needle-free connection devices using different disinfection procedures

    PubMed Central

    Engelhart, Steffen; Exner, Martin; Simon, Arne

    2015-01-01

    This in vitro study investigated the external disinfection of two needle-free connection devices (NFC) using Octeniderm® (spraying and wiping technique) vs. Descoderm® pads (wiping technique). The split-septum membrane of the NFC was contaminated with >105 CFU K. pneumoniae or S. epidermidis. The efficacy of the disinfection at 30 sec. exposure time was controlled by taking a swab sample and by flushing the NFC with sterile 0.9% sodium chloride solution. Disinfection with octenidine dihydrochloride 0.1 g, 1-Propanol 30.0 g, and 2-Propanol 45.0 g in 100 g solution was highly effective (CFU reduction ≥4 log) against both microorganisms, whereas the use of 63.1 g 2-Propanol in 100 ml solution led to residual contamination with S. epidermidis. Our investigation underlines that (i) in clinical practice disinfection of NFCs before use is mandatory, and that (ii) details of disinfection technique are of utmost importance regarding their efficacy. Our investigation revealed no significant differences between both split-septum NFC types. Clinical studies are needed to confirm a possible superiority of disinfectants with long-lasting residual antimicrobial activity. PMID:26693394

  16. Electric field metrology for SI traceability: Systematic measurement uncertainties in electromagnetically induced transparency in atomic vapor

    NASA Astrophysics Data System (ADS)

    Holloway, Christopher L.; Simons, Matt T.; Gordon, Joshua A.; Dienstfrey, Andrew; Anderson, David A.; Raithel, Georg

    2017-06-01

    We investigate the relationship between the Rabi frequency (ΩRF, related to the applied electric field) and Autler-Townes (AT) splitting, when performing atom-based radio-frequency (RF) electric (E) field strength measurements using Rydberg states and electromagnetically induced transparency (EIT) in an atomic vapor. The AT splitting satisfies, under certain conditions, a well-defined linear relationship with the applied RF field amplitude. The EIT/AT-based E-field measurement approach derived from these principles is currently being investigated by several groups around the world as a means to develop a new SI-traceable RF E-field measurement technique. We establish conditions under which the measured AT-splitting is an approximately linear function of the RF electric field. A quantitative description of systematic deviations from the linear relationship is key to exploiting EIT/AT-based atomic-vapor spectroscopy for SI-traceable field measurement. We show that the linear relationship is valid and can be used to determine the E-field strength, with minimal error, as long as the EIT linewidth is small compared to the AT-splitting. We also discuss interesting aspects of the thermal dependence (i.e., hot- versus cold-atom) of this EIT-AT technique. An analysis of the transition from cold- to hot-atom EIT in a Doppler-mismatched cascade system reveals a significant change of the dependence of the EIT linewidth on the optical Rabi frequencies and of the AT-splitting on ΩRF.

  17. Evaluation of Mandibular Anatomy Associated With Bad Splits in Sagittal Split Ramus Osteotomy of Mandible.

    PubMed

    Wang, Tongyue; Han, Jeong Joon; Oh, Hee-Kyun; Park, Hong-Ju; Jung, Seunggon; Park, Yeong-Joon; Kook, Min-Suk

    2016-07-01

    This study aimed to identify risk factors associated with bad splits during sagittal split ramus osteotomy by using three-dimensional computed tomography. This study included 8 bad splits and 47 normal patients without bad splits. Mandibular anatomic parameters related to osteotomy line were measured. These included anteroposterior width of the ramus at level of lingula, distance between external oblique ridge and lingula, distance between sigmoid notch and inferior border of mandible, mandibular angle, distance between inferior outer surface of mandibular canal and inferior border of mandible under distal root of second molar (MCEM), buccolingual thickness of the ramus at level of lingula, and buccolingual thickness of the area just distal to first molar (BTM1) and second molar (BTM2). The incidence of bad splits in 625 sagittal split osteotomies was 1.28%. Compared with normal group, bad split group exhibited significantly thinner BTM2 and shorter sigmoid notch and inferior border of mandible (P <0.05). However, for BTM1 and buccolingual thickness of the ramus at level of lingula, there was no statistical difference between the 2 groups. Mandibular angle, anteroposterior width of the ramus at level of lingula, external oblique ridge and lingula, and MCEM were not significantly different between the groups. This study suggests that patients with shorter ramus and low thickness of the buccolingual alveolar region distal to the second molar had a higher risk of bad splits. These anatomic data may help surgeons to choose the safest surgical techniques and best osteotomy sites.

  18. Novel Histogram Based Unsupervised Classification Technique to Determine Natural Classes From Biophysically Relevant Fit Parameters to Hyperspectral Data

    DOE PAGES

    McCann, Cooper; Repasky, Kevin S.; Morin, Mikindra; ...

    2017-05-23

    Hyperspectral image analysis has benefited from an array of methods that take advantage of the increased spectral depth compared to multispectral sensors; however, the focus of these developments has been on supervised classification methods. Lack of a priori knowledge regarding land cover characteristics can make unsupervised classification methods preferable under certain circumstances. An unsupervised classification technique is presented in this paper that utilizes physically relevant basis functions to model the reflectance spectra. These fit parameters used to generate the basis functions allow clustering based on spectral characteristics rather than spectral channels and provide both noise and data reduction. Histogram splittingmore » of the fit parameters is then used as a means of producing an unsupervised classification. Unlike current unsupervised classification techniques that rely primarily on Euclidian distance measures to determine similarity, the unsupervised classification technique uses the natural splitting of the fit parameters associated with the basis functions creating clusters that are similar in terms of physical parameters. The data set used in this work utilizes the publicly available data collected at Indian Pines, Indiana. This data set provides reference data allowing for comparisons of the efficacy of different unsupervised data analysis. The unsupervised histogram splitting technique presented in this paper is shown to be better than the standard unsupervised ISODATA clustering technique with an overall accuracy of 34.3/19.0% before merging and 40.9/39.2% after merging. Finally, this improvement is also seen as an improvement of kappa before/after merging of 24.8/30.5 for the histogram splitting technique compared to 15.8/28.5 for ISODATA.« less

  19. Novel Histogram Based Unsupervised Classification Technique to Determine Natural Classes From Biophysically Relevant Fit Parameters to Hyperspectral Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCann, Cooper; Repasky, Kevin S.; Morin, Mikindra

    Hyperspectral image analysis has benefited from an array of methods that take advantage of the increased spectral depth compared to multispectral sensors; however, the focus of these developments has been on supervised classification methods. Lack of a priori knowledge regarding land cover characteristics can make unsupervised classification methods preferable under certain circumstances. An unsupervised classification technique is presented in this paper that utilizes physically relevant basis functions to model the reflectance spectra. These fit parameters used to generate the basis functions allow clustering based on spectral characteristics rather than spectral channels and provide both noise and data reduction. Histogram splittingmore » of the fit parameters is then used as a means of producing an unsupervised classification. Unlike current unsupervised classification techniques that rely primarily on Euclidian distance measures to determine similarity, the unsupervised classification technique uses the natural splitting of the fit parameters associated with the basis functions creating clusters that are similar in terms of physical parameters. The data set used in this work utilizes the publicly available data collected at Indian Pines, Indiana. This data set provides reference data allowing for comparisons of the efficacy of different unsupervised data analysis. The unsupervised histogram splitting technique presented in this paper is shown to be better than the standard unsupervised ISODATA clustering technique with an overall accuracy of 34.3/19.0% before merging and 40.9/39.2% after merging. Finally, this improvement is also seen as an improvement of kappa before/after merging of 24.8/30.5 for the histogram splitting technique compared to 15.8/28.5 for ISODATA.« less

  20. Split Space-Marching Finite-Volume Method for Chemically Reacting Supersonic Flow

    NASA Technical Reports Server (NTRS)

    Rizzi, Arthur W.; Bailey, Harry E.

    1976-01-01

    A space-marching finite-volume method employing a nonorthogonal coordinate system and using a split differencing scheme for calculating steady supersonic flow over aerodynamic shapes is presented. It is a second-order-accurate mixed explicit-implicit procedure that solves the inviscid adiabatic and nondiffusive equations for chemically reacting flow in integral conservation-law form. The relationship between the finite-volume and differential forms of the equations is examined and the relative merits of each discussed. The method admits initial Cauchy data situated on any arbitrary surface and integrates them forward along a general curvilinear coordinate, distorting and deforming the surface as it advances. The chemical kinetics term is split from the convective terms which are themselves dimensionally split, thereby freeing the fluid operators from the restricted step size imposed by the chemical reactions and increasing the computational efficiency. The accuracy of this splitting technique is analyzed, a sufficient stability criterion is established, a representative flow computation is discussed, and some comparisons are made with another method.

  1. Bubble transport in bifurcations

    NASA Astrophysics Data System (ADS)

    Bull, Joseph; Qamar, Adnan

    2017-11-01

    Motivated by a developmental gas embolotherapy technique for cancer treatment, we examine the transport of bubbles entrained in liquid. In gas embolotherapy, infarction of tumors is induced by selectively formed vascular gas bubbles that originate from acoustic vaporization of vascular droplets. In the case of non-functionalized droplets with the objective of vessel occlusion, the bubbles are transported by flow through vessel bifurcations, where they may split prior to eventually reach vessels small enough that they become lodged. This splitting behavior affects the distribution of bubbles and the efficacy of flow occlusion and the treatment. In these studies, we investigated bubble transport in bifurcations using computational and theoretical modeling. The model reproduces the variety of experimentally observed splitting behaviors. Splitting homogeneity and maximum shear stress along the vessel walls is predicted over a variety of physical parameters. Maximum shear stresses were found to decrease with increasing Reynolds number. The initial bubble length was found to affect the splitting behavior in the presence of gravitational asymmetry. This work was supported by NIH Grant R01EB006476.

  2. Precision ESR Measurements of Transverse Anisotropy in the Single-molecule Magnet Ni4

    NASA Astrophysics Data System (ADS)

    Friedman, Jonathan; Collett, Charles; Allao Cassaro, Rafael

    We present a method to precisely determine the transverse anisotropy in a single-molecule magnet (SMM) through electron-spin resonance measurements of a tunnel splitting that arises from the anisotropy via first-order perturbation theory. We demonstrate the technique using the SMM Ni4 diluted via co-crystallization in a diamagnetic isostructural analogue. At 5% dilution, we find markedly narrower resonance peaks than are observed in undiluted samples. Ni4 has a zero-field tunnel splitting of 4 GHz, and we measure that transition at several nearby frequencies using custom loop-gap resonators, allowing a precise determination of the tunnel splitting. Because the transition under investigation arises due to a first-order perturbation from the transverse anisotropy, and lies at zero field, we can relate the splitting to the transverse anisotropy independent of any other Hamiltonian parameters. This method can be applied to other SMMs with zero-field tunnel splittings arising from first-order transverse anisotropy perturbations. NSF Grant No. DMR-1310135.

  3. New Photocatalysts for Hydrogen Production; Nuevos Fotocatalizadores para la Producción de Hidrógeno

    DOE PAGES

    García, Abraham; Cotto, María; Duconge, José; ...

    2014-06-10

    The use of hydrogen as replacement for fossil fuels, on which we depend today, is a matter of great relevance. The sustainable generation of hydrogen as fuel is relevant from an environmental and economic point of view. In this study we have explored new synthetic routes for developing new photocatalysts to be used in water splitting, for hydrogen production. Different techniques have been used to produce hydrogen, such as electrolysis, even though these processes have been found to be energetically non suitable. In this research various photocatalytic materials were presented as possible alternatives for using in water splitting processes. Characterizationmore » of the new synthesized materials has been done by using different experimental techniques including Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), surface area BET, and X-ray Diffraction (XRD). The efficiency of the synthesized photocatalysts was determined by evaluating the hydrogen evolution by the photocatalytic water splitting reaction.« less

  4. Physical-geometric optics method for large size faceted particles.

    PubMed

    Sun, Bingqiang; Yang, Ping; Kattawar, George W; Zhang, Xiaodong

    2017-10-02

    A new physical-geometric optics method is developed to compute the single-scattering properties of faceted particles. It incorporates a general absorption vector to accurately account for inhomogeneous wave effects, and subsequently yields the relevant analytical formulas effective and computationally efficient for absorptive scattering particles. A bundle of rays incident on a certain facet can be traced as a single beam. For a beam incident on multiple facets, a systematic beam-splitting technique based on computer graphics is used to split the original beam into several sub-beams so that each sub-beam is incident only on an individual facet. The new beam-splitting technique significantly reduces the computational burden. The present physical-geometric optics method can be generalized to arbitrary faceted particles with either convex or concave shapes and with a homogeneous or an inhomogeneous (e.g., a particle with a core) composition. The single-scattering properties of irregular convex homogeneous and inhomogeneous hexahedra are simulated and compared to their counterparts from two other methods including a numerically rigorous method.

  5. One‐dimensional TiO2 Nanotube Photocatalysts for Solar Water Splitting

    PubMed Central

    Ge, Mingzheng; Li, Qingsong; Cao, Chunyan; Huang, Jianying; Li, Shuhui; Zhang, Songnan; Chen, Zhong; Zhang, Keqin; Al‐Deyab, Salem S.

    2016-01-01

    Hydrogen production from water splitting by photo/photoelectron‐catalytic process is a promising route to solve both fossil fuel depletion and environmental pollution at the same time. Titanium dioxide (TiO2) nanotubes have attracted much interest due to their large specific surface area and highly ordered structure, which has led to promising potential applications in photocatalytic degradation, photoreduction of CO2, water splitting, supercapacitors, dye‐sensitized solar cells, lithium‐ion batteries and biomedical devices. Nanotubes can be fabricated via facile hydrothermal method, solvothermal method, template technique and electrochemical anodic oxidation. In this report, we provide a comprehensive review on recent progress of the synthesis and modification of TiO2 nanotubes to be used for photo/photoelectro‐catalytic water splitting. The future development of TiO2 nanotubes is also discussed. PMID:28105391

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    He, Yang; Xiao, Jianyuan; Zhang, Ruili

    Hamiltonian time integrators for the Vlasov-Maxwell equations are developed by a Hamiltonian splitting technique. The Hamiltonian functional is split into five parts, which produces five exactly solvable subsystems. Each subsystem is a Hamiltonian system equipped with the Morrison-Marsden-Weinstein Poisson bracket. Compositions of the exact solutions provide Poisson structure preserving/Hamiltonian methods of arbitrary high order for the Vlasov-Maxwell equations. They are then accurate and conservative over a long time because of the Poisson-preserving nature.

  7. Investigation of mantle kinematics beneath the Hellenic-subduction zone with teleseismic direct shear waves

    NASA Astrophysics Data System (ADS)

    Confal, Judith M.; Eken, Tuna; Tilmann, Frederik; Yolsal-Çevikbilen, Seda; Çubuk-Sabuncu, Yeşim; Saygin, Erdinc; Taymaz, Tuncay

    2016-12-01

    The subduction and roll-back of the African plate beneath the Eurasian plate along the arcuate Hellenic trench is the dominant geodynamic process in the Aegean and western Anatolia. Mantle flow and lithospheric kinematics in this region can potentially be understood better by mapping seismic anisotropy. This study uses direct shear-wave splitting measurements based on the Reference Station Technique in the southern Aegean Sea to reveal seismic anisotropy in the mantle. The technique overcomes possible contamination from source-side anisotropy on direct S-wave signals recorded at a station pair by maximizing the correlation between the seismic traces at reference and target stations after correcting the reference stations for known receiver-side anisotropy and the target stations for arbitrary splitting parameters probed via a grid search. We obtained splitting parameters at 35 stations with good-quality S-wave signals extracted from 81 teleseismic events. Employing direct S-waves enabled more stable and reliable splitting measurements than previously possible, based on sparse SKS data at temporary stations, with one to five events for local SKS studies, compared with an average of 12 events for each station in this study. The fast polarization directions mostly show NNE-SSW orientation with splitting time delays between 1.15 s and 1.62 s. Two stations in the west close to the Hellenic Trench and one in the east show N-S oriented fast polarizations. In the back-arc region three stations exhibit NE-SW orientation. The overall fast polarization variations tend to be similar to those obtained from previous SKS splitting studies in the region but indicate a more consistent pattern, most likely due to the usage of a larger number of individual observations in direct S-wave derived splitting measurements. Splitting analysis on direct shear waves typically resulted in larger split time delays compared to previous studies, possibly because S-waves travel along a longer path in the same anisotropic structure. Considering the S-derived splitting measurements of this study together with earlier SKS and Rayleigh wave anisotropy modelling results we suggest that the very consistent direct S-derived fast shear wave directions can be explained by the lattice-preferred orientation of olivine in the asthenospheric mantle due to mantle flow induced by the roll-back of the slab. It is possible that a small contribution originated in the lower crust beneath the study region where anisotropic fabric might have formed in response to extension in the Miocene.

  8. Accuracy of tablet splitting and liquid measurements: an examination of who, what and how.

    PubMed

    Abu-Geras, Dana; Hadziomerovic, Dunja; Leau, Andrew; Khan, Ramzan Nazim; Gudka, Sajni; Locher, Cornelia; Razaghikashani, Maryam; Lim, Lee Yong

    2017-05-01

    To examine factors that might affect the ability of patients to accurately halve tablets or measure a 5-ml liquid dose. Eighty-eight participants split four different placebo tablets by hand and using a tablet splitter, while 85 participants measured 5 ml of water, 0.5% methylcellulose (MC) and 1% MC using a syringe and dosing cup. Accuracy of manipulation was determined by mass measurements. The general population was less able than pharmacy students to break tablets into equal parts, although age, gender and prior experience were insignificant factors. Greater accuracy of tablet halving was observed with tablet splitter, with scored tablets split more equally than unscored tablets. Tablet size did not affect the accuracy of splitting. However, >25% of small scored tablets failed to be split by hand, and 41% of large unscored tablets were split into >2 portions in the tablet splitter. In liquid measurement, the syringe provided more accurate volume measurements than the dosing cup, with higher accuracy observed for the more viscous MC solutions than water. Formulation characteristics and manipulation technique have greater influences on the accuracy of medication modification and should be considered in off-label drug use in vulnerable populations. © 2016 Royal Pharmaceutical Society.

  9. The practice and clinical implications of tablet splitting in international health

    PubMed Central

    Elliott, Ivo; Mayxay, Mayfong; Yeuichaixong, Sengchanh; Lee, Sue J; Newton, Paul N

    2014-01-01

    Objective Tablet splitting is frequently performed to facilitate correct dosing, but the practice and implications in low-income settings have rarely been discussed. Methods We selected eight drugs, with narrow therapeutic indices or critical dosages, frequently divided in the Lao PDR (Laos). These were split, by common techniques used in Laos, by four nurses and four laypersons. The mean percentage deviation from the theoretical expected weight and weight loss of divided tablets/capsules were recorded. Results Five of eight study drugs failed, on splitting, to meet European Pharmacopoeia recommendations for tablet weight deviation from the expected weight of tablet/capsule halves with 10% deviating by more than 25%. There was a significant difference in splitting accuracy between nurses and laypersons (P = 0.027). Coated and unscored tablets were less accurately split than uncoated (P = 0.03 and 0.0019 for each half) and scored (0.0001 for both halves) tablets. Conclusion These findings have potential clinical implications on treatment outcome and the development of antimicrobial resistance. Investment by drug companies in a wider range of dosage units, particularly for narrow therapeutic index and critical dosage medicines, is strongly recommended. PMID:24702766

  10. Rouleaux red blood cells splitting in microscopic thin blood smear images via local maxima, circles drawing, and mapping with original RBCs.

    PubMed

    Rehman, Amjad; Abbas, Naveed; Saba, Tanzila; Mahmood, Toqeer; Kolivand, Hoshang

    2018-04-10

    Splitting the rouleaux RBCs from single RBCs and its further subdivision is a challenging area in computer-assisted diagnosis of blood. This phenomenon is applied in complete blood count, anemia, leukemia, and malaria tests. Several automated techniques are reported in the state of art for this task but face either under or over splitting problems. The current research presents a novel approach to split Rouleaux red blood cells (chains of RBCs) precisely, which are frequently observed in the thin blood smear images. Accordingly, this research address the rouleaux splitting problem in a realistic, efficient and automated way by considering the distance transform and local maxima of the rouleaux RBCs. Rouleaux RBCs are splitted by taking their local maxima as the centres to draw circles by mid-point circle algorithm. The resulting circles are further mapped with single RBC in Rouleaux to preserve its original shape. The results of the proposed approach on standard data set are presented and analyzed statistically by achieving an average recall of 0.059, an average precision of 0.067 and F-measure 0.063 are achieved through ground truth with visual inspection. © 2018 Wiley Periodicals, Inc.

  11. Atomic-scale distortion of optically activated Sm dopants identified with site-selective X-ray absorption spectroscopy

    NASA Astrophysics Data System (ADS)

    Ishii, Masashi; Crowe, Iain F.; Halsall, Matthew P.; Hamilton, Bruce; Hu, Yongfeng; Sham, Tsun-Kong; Harako, Susumu; Zhao, Xin-Wei; Komuro, Shuji

    2013-10-01

    The local structure of luminescent Sm dopants was investigated using an X-ray absorption fine-structure technique with X-ray-excited optical luminescence. Because this technique evaluates X-ray absorption from luminescence, only optically active sites are analyzed. The Sm L3 near-edge spectrum contains split 5d states and a shake-up transition that are specific to luminescent Sm. Theoretical calculations using cluster models identified an atomic-scale distortion that can reproduce the split 5d states. The model with C4v local symmetry and compressive bond length of Sm-O of a six-fold oxygen (SmO6) cluster is most consistent with the experimental results.

  12. An efficient three-dimensional Poisson solver for SIMD high-performance-computing architectures

    NASA Technical Reports Server (NTRS)

    Cohl, H.

    1994-01-01

    We present an algorithm that solves the three-dimensional Poisson equation on a cylindrical grid. The technique uses a finite-difference scheme with operator splitting. This splitting maps the banded structure of the operator matrix into a two-dimensional set of tridiagonal matrices, which are then solved in parallel. Our algorithm couples FFT techniques with the well-known ADI (Alternating Direction Implicit) method for solving Elliptic PDE's, and the implementation is extremely well suited for a massively parallel environment like the SIMD architecture of the MasPar MP-1. Due to the highly recursive nature of our problem, we believe that our method is highly efficient, as it avoids excessive interprocessor communication.

  13. Scar due to skin incision for screw fixation through the transbuccal approach after sagittal split ramus osteotomy.

    PubMed

    Muto, Toshitaka

    2012-05-01

    Most rigid fixation techniques after sagittal split ramus osteotomies of the mandible involve the transbuccal approach. A skin incision in the cheek carries with it possible undesirable sequelae, such as noticeable scarring. The aim of this study was to investigate whether there is scarring in the face after this technique. For screw insertion, a 5-mm stab incision was performed on 40 Japanese patients (20 men and 20 women) with class III occlusion. After surgery, gross examination (via the naked eyes) of the skin incision was performed monthly for 1 year by the same oral surgeon. In all cases, the skin incision had disappeared by 1 year after the surgery.

  14. In Vivo Imaging of Human Cone Photoreceptor Inner Segments

    PubMed Central

    Scoles, Drew; Sulai, Yusufu N.; Langlo, Christopher S.; Fishman, Gerald A.; Curcio, Christine A.; Carroll, Joseph; Dubra, Alfredo

    2014-01-01

    Purpose. An often overlooked prerequisite to cone photoreceptor gene therapy development is residual photoreceptor structure that can be rescued. While advances in adaptive optics (AO) retinal imaging have recently enabled direct visualization of individual cone and rod photoreceptors in the living human retina, these techniques largely detect strongly directionally-backscattered (waveguided) light from normal intact photoreceptors. This represents a major limitation in using existing AO imaging to quantify structure of remnant cones in degenerating retina. Methods. Photoreceptor inner segment structure was assessed with a novel AO scanning light ophthalmoscopy (AOSLO) differential phase technique, that we termed nonconfocal split-detector, in two healthy subjects and four subjects with achromatopsia. Ex vivo preparations of five healthy donor eyes were analyzed for comparison of inner segment diameter to that measured in vivo with split-detector AOSLO. Results. Nonconfocal split-detector AOSLO reveals the photoreceptor inner segment with or without the presence of a waveguiding outer segment. The diameter of inner segments measured in vivo is in good agreement with histology. A substantial number of foveal and parafoveal cone photoreceptors with apparently intact inner segments were identified in patients with the inherited disease achromatopsia. Conclusions. The application of nonconfocal split-detector to emerging human gene therapy trials will improve the potential of therapeutic success, by identifying patients with sufficient retained photoreceptor structure to benefit the most from intervention. Additionally, split-detector imaging may be useful for studies of other retinal degenerations such as AMD, retinitis pigmentosa, and choroideremia where the outer segment is lost before the remainder of the photoreceptor cell. PMID:24906859

  15. Surgical Anatomy of the Left Lateral Segment as Applied to Living-Donor and Split-Liver Transplantation

    PubMed Central

    Reichert, Paulo R.; Renz, John F.; D’Albuquerque, Luiz A. C.; Rosenthal, Philip; Lim, Robert C.; Roberts, John P.; Ascher, Nancy L.; Emond, Jean C.

    2000-01-01

    Objective To evaluate intrahepatic vascular and biliary anatomy of the left lateral segment (LLS) as applied to living-donor and split-liver transplantation. Summary Background Data Living-donor and split-liver transplantation are innovative surgical techniques that have expanded the donor pool. Fundamental to the application of these techniques is an understanding of intrahepatic vascular and biliary anatomy. Methods Pathologic data obtained from cadaveric liver corrosion casts and liver dissections were clinically correlated with the anatomical findings obtained during split-liver, living-donor, and reduced-liver transplants. Results The anatomical relation of the left bile duct system with respect to the left portal venous system was constant, with the left bile duct superior to the extrahepatic transverse portion of the left portal vein. Four specific patterns of left biliary anatomy and three patterns of left hepatic venous drainage were identified and described. Conclusions Although highly variable, the biliary and hepatic venous anatomy of the LLS can be broadly categorized into distinct patterns. The identification of the LLS duct origin lateral to the umbilical fissure in segment 4 in 50% of cast specimens is significant in the performance of split-liver and living-donor transplantation, because dissection of the graft pedicle at the level of the round ligament will result in separate ducts from segments 2 and 3 in most patients, with the further possibility of an anterior segment 4 duct. A connective tissue bile duct plate, which can be clinically identified, is described to guide dissection of the segment 2 and 3 biliary radicles. PMID:11066137

  16. Cool covered sky-splitting spectrum-splitting FK

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mohedano, Rubén; Chaves, Julio; Falicoff, Waqidi

    2014-09-26

    Placing a plane mirror between the primary lens and the receiver in a Fresnel Köhler (FK) concentrator gives birth to a quite different CPV system where all the high-tech components sit on a common plane, that of the primary lens panels. The idea enables not only a thinner device (a half of the original) but also a low cost 1-step manufacturing process for the optics, automatic alignment of primary and secondary lenses, and cell/wiring protection. The concept is also compatible with two different techniques to increase the module efficiency: spectrum splitting between a 3J and a BPC Silicon cell formore » better usage of Direct Normal Irradiance DNI, and sky splitting to harvest the energy of the diffuse radiation and higher energy production throughout the year. Simple calculations forecast the module would convert 45% of the DNI into electricity.« less

  17. The development of flux-split algorithms for flows with non-equilibrium thermodynamics and chemical reactions

    NASA Technical Reports Server (NTRS)

    Grossman, B.; Cinella, P.

    1988-01-01

    A finite-volume method for the numerical computation of flows with nonequilibrium thermodynamics and chemistry is presented. A thermodynamic model is described which simplifies the coupling between the chemistry and thermodynamics and also results in the retention of the homogeneity property of the Euler equations (including all the species continuity and vibrational energy conservation equations). Flux-splitting procedures are developed for the fully coupled equations involving fluid dynamics, chemical production and thermodynamic relaxation processes. New forms of flux-vector split and flux-difference split algorithms are embodied in a fully coupled, implicit, large-block structure, including all the species conservation and energy production equations. Several numerical examples are presented, including high-temperature shock tube and nozzle flows. The methodology is compared to other existing techniques, including spectral and central-differenced procedures, and favorable comparisons are shown regarding accuracy, shock-capturing and convergence rates.

  18. Facile Preparation of Porous WO3 Film for Photoelectrochemical Splitting of Natural Seawater

    NASA Astrophysics Data System (ADS)

    Shi, Yonghong; Li, Yuangang; Wei, Xiaoliang; Feng, Juan; Li, Huajing; Zhou, Wanyi

    2017-12-01

    Sunlight-driven natural seawater splitting provides a promising way for large-scale conversion and storage of solar energy. Here, we develop a facile and low-cost method via a deposition-annealing technique to fabricate porous WO3 film and demonstrate its application as a photoanode for natural seawater splitting. The WO3 film yields a photocurrent density of 1.95 mA cm-2 and possesses excellent stability at 1.23 V (versus RHE), under the illumination of 100 mW cm-2 (AM 1.5G). The photoelectrochemical performance is ascribed to the large surface area and good permeation of the electrolyte into the porous film. Furthermore, the photocurrent density remains almost the same during 3 h continuous light irradiation. The evolution of chlorine gas from seawater splitting was determined with qualitative and quantitative analyses, with a Faradic efficiency of about 56%.

  19. Image-Guided Internal Fixation of an Oblique Sagittal Split Fracture of C1 Lateral Mass with Motion Preservation: A Technical Report.

    PubMed

    Malcolm, James G; Tan, Lee A; Johnson, Andrew K

    2017-07-20

    A sagittal split fracture of the C1 lateral mass is an unstable subtype of C1 fractures and has a high propensity for developing late deformities and pain with nonoperative management. A primary internal fixation of this type of fracture has been recently described with good clinical outcomes and preservation of motion. We present a modified technique of primary internal fixation using an obliquely inserted C1 lag screw with imaging guidance. We successfully treated a 55-year-old woman with a unilateral C1 oblique sagittal split fracture who failed nonoperative management. Technical nuances are discussed with a review of pertinent literature.

  20. Image splitting and remapping method for radiological image compression

    NASA Astrophysics Data System (ADS)

    Lo, Shih-Chung B.; Shen, Ellen L.; Mun, Seong K.

    1990-07-01

    A new decomposition method using image splitting and gray-level remapping has been proposed for image compression, particularly for images with high contrast resolution. The effects of this method are especially evident in our radiological image compression study. In our experiments, we tested the impact of this decomposition method on image compression by employing it with two coding techniques on a set of clinically used CT images and several laser film digitized chest radiographs. One of the compression techniques used was full-frame bit-allocation in the discrete cosine transform domain, which has been proven to be an effective technique for radiological image compression. The other compression technique used was vector quantization with pruned tree-structured encoding, which through recent research has also been found to produce a low mean-square-error and a high compression ratio. The parameters we used in this study were mean-square-error and the bit rate required for the compressed file. In addition to these parameters, the difference between the original and reconstructed images will be presented so that the specific artifacts generated by both techniques can be discerned by visual perception.

  1. The new management policy: Indonesian PSC-Gross split applied on CO2 flooding project

    NASA Astrophysics Data System (ADS)

    Irham, S.; Sibuea, S. N.; Danu, A.

    2018-01-01

    “SIAD” oil field will be developed by CO2 flooding. CO2, a famous pollutant gas, is injected into the oil reservoir to optimize the oil recovery. This technique should be conducted economically according to the energy management policy in Indonesia. In general, Indonesia has two policy contracts on oil and gas: the old one is PSC-Cost-Recovery, and the new one is PSC-Gross-Split (introduced in 2017 as the new energy management plan). The contractor must choose between PSC-Cost-Recovery and PSC-Gross-Split which makes more profit. The aim of this paper is to show the best oil and gas contract policy for the contractor. The methods are calculating and comparing the economic indicators. The result of this study are (1) NPV for the PSC-Cost-Recovery is -46 MUS, while for the PSC-Gross-Split is 73 MUS, and (2) IRR for the PSC-Cost-Recovery is 9%, whereas for the PSC-Gross-Split is 11%. The conclusion is that the NPV and IRR for PSC-Gross-Split are greater than the NPV and IRR of PSC-Cost-Recovery, but POT in PSC-Gross-split is longer than POT in PSC-Cost-Recovery. Thus, in this case, the new energy policy contract can be applied for CO2 flooding technology since it yields higher economic indicators than its antecendent.

  2. Valley Zeeman splitting of monolayer MoS2 probed by low-field magnetic circular dichroism spectroscopy at room temperature

    NASA Astrophysics Data System (ADS)

    Wu, Y. J.; Shen, C.; Tan, Q. H.; Shi, J.; Liu, X. F.; Wu, Z. H.; Zhang, J.; Tan, P. H.; Zheng, H. Z.

    2018-04-01

    The valley Zeeman splitting of monolayer two-dimensional (2D) materials in the magnetic field plays an important role in the valley and spin manipulations. In general, a high magnetic field (6-65 T) and low temperature (2-30 K) were two key measurement conditions to observe the resolvable valley Zeeman splitting of monolayer 2D materials in current reported experiments. In this study, we experimentally demonstrate an effective measurement scheme by employing magnetic circular dichroism (MCD) spectroscopy, which enables us to distinguish the valley Zeeman splitting under a relatively low magnetic field of 1 T at room temperature. MCD peaks related to both A and B excitonic transitions in monolayer MoS2 can be clearly observed. Based on the MCD spectra under different magnetic fields (-3 to 3 T), we obtained the valley Zeeman splitting energy and the g-factors of A and B excitons, respectively. Our results show that MCD spectroscopy is a high-sensitive magneto-optical technique to explore the valley and spin manipulation in 2D materials.

  3. Development of new flux splitting schemes. [computational fluid dynamics algorithms

    NASA Technical Reports Server (NTRS)

    Liou, Meng-Sing; Steffen, Christopher J., Jr.

    1992-01-01

    Maximizing both accuracy and efficiency has been the primary objective in designing a numerical algorithm for computational fluid dynamics (CFD). This is especially important for solutions of complex three dimensional systems of Navier-Stokes equations which often include turbulence modeling and chemistry effects. Recently, upwind schemes have been well received for their capability in resolving discontinuities. With this in mind, presented are two new flux splitting techniques for upwind differencing. The first method is based on High-Order Polynomial Expansions (HOPE) of the mass flux vector. The second new flux splitting is based on the Advection Upwind Splitting Method (AUSM). The calculation of the hypersonic conical flow demonstrates the accuracy of the splitting in resolving the flow in the presence of strong gradients. A second series of tests involving the two dimensional inviscid flow over a NACA 0012 airfoil demonstrates the ability of the AUSM to resolve the shock discontinuity at transonic speed. A third case calculates a series of supersonic flows over a circular cylinder. Finally, the fourth case deals with tests of a two dimensional shock wave/boundary layer interaction.

  4. Conceptual Design and Optimal Power Control Strategy for AN Eco-Friendly Hybrid Vehicle

    NASA Astrophysics Data System (ADS)

    Nasiri, N. Mir; Chieng, Frederick T. A.

    2011-06-01

    This paper presents a new concept for a hybrid vehicle using a torque and speed splitting technique. It is implemented by the newly developed controller in combination with a two degree of freedom epicyclic gear transmission. This approach enables optimization of the power split between the less powerful electrical motor and more powerful engine while driving a car load. The power split is fundamentally a dual-energy integration mechanism as it is implemented by using the epicyclic gear transmission that has two inputs and one output for a proper power distribution. The developed power split control system manages the operation of both the inputs to have a known output with the condition of maintaining optimum operating efficiency of the internal combustion engine and electrical motor. This system has a huge potential as it is possible to integrate all the features of hybrid vehicle known to-date such as the regenerative braking system, series hybrid, parallel hybrid, series/parallel hybrid, and even complex hybrid (bidirectional). By using the new power split system it is possible to further reduce fuel consumption and increase overall efficiency.

  5. Reconstruction of Knee Defects Using Pedicled Gastrocnemius Muscle Flap with Split-Thickness Skin Grafting: A Single Surgeon's Experience with 21 Patients.

    PubMed

    Kilic, Ali; Denney, Brad; de la Torre, Jorge

    2018-05-31

    Generally, reconstruction of knee defects with exposed bone, joint, tendon, and/or hardware requires a vascularized muscle flap for coverage. Although there are several surgical options for a knee defect reconstruction, the pedicled gastrocnemius muscle still remains the workhorse flap. Although this flap is commonly used for knee defect reconstruction and the technique is described very well, there is an absence of information in the literature detailing the technique of harvesting and insetting of the gastrocnemius flap step by step with illustrations. The purpose of this article is to describe in detail the technique to reconstruct defects of the knee with pedicled gastrocnemius muscle flap as well as to present demographics and surgical results of 21 patients who had knee reconstruction with a pedicled gastrocnemius muscle flap and split-thickness skin grafting. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  6. Split liver transplantation in adults.

    PubMed

    Hashimoto, Koji; Fujiki, Masato; Quintini, Cristiano; Aucejo, Federico N; Uso, Teresa Diago; Kelly, Dympna M; Eghtesad, Bijan; Fung, John J; Miller, Charles M

    2016-09-07

    Split liver transplantation (SLT), while widely accepted in pediatrics, remains underutilized in adults. Advancements in surgical techniques and donor-recipient matching, however, have allowed expansion of SLT from utilization of the right trisegment graft to now include use of the hemiliver graft as well. Despite less favorable outcomes in the early experience, better outcomes have been reported by experienced centers and have further validated the feasibility of SLT. Importantly, more than two decades of experience have identified key requirements for successful SLT in adults. When these requirements are met, SLT can achieve outcomes equivalent to those achieved with other types of liver transplantation for adults. However, substantial challenges, such as surgical techniques, logistics, and ethics, persist as ongoing barriers to further expansion of this highly complex procedure. This review outlines the current state of SLT in adults, focusing on donor and recipient selection based on physiology, surgical techniques, surgical outcomes, and ethical issues.

  7. An in vitro evaluation of rigid internal fixation techniques for sagittal split ramus osteotomies: setback surgery.

    PubMed

    Brasileiro, Bernardo Ferreira; Grotta-Grempel, Rafael; Ambrosano, Glaucia Maria Bovi; Passeri, Luis Augusto

    2012-04-01

    The aim of this study was to evaluate the biomechanical features of 3 different methods of rigid internal fixation for sagittal split ramus osteotomy for mandibular setback in vitro. Sixty polyurethane replicas of human hemimandibles were used as substrates, simulating a 5-mm setback surgery by sagittal split ramus osteotomy. These replicas served to reproduce 3 different techniques of fixation, including 1) a 4-hole plate and 4 monocortical screws (miniplate group), 2) a 4-hole plate and 4 monocortical screws with 1 additional bicortical positional screw (hybrid group), and 3) 3 bicortical positional screws in a traditional inverted-L pattern (inverted-L group). After fixation, hemimandibles were adapted to a test support and subjected to lateral torsional forces on the buccal molar surface and vertical cantilever loading on the incisal edge with an Instron 4411 mechanical testing unit. Peak loadings at 1, 3, 5, and 10 mm of displacement were recorded. Means and standard deviation were analyzed using analysis of variance and Tukey test with a 5% level of significance, and failures during tests were recorded. Regardless of the amount of displacement and direction of force, the miniplate group always showed the lowest load peak scores (P < .01) compared with the other fixation techniques. The hybrid group demonstrated behavior similar to the inverted-L group in lateral and vertical forces at any loading displacement (P > .05). Molar load tests required more force than incisal load tests to promote the same displacement in the mandibular setback model (P < .05). For mandibular setback surgery of 5 mm, this study concluded that the fixation technique based on the miniplate group was significantly less rigid than the fixation observed in the hybrid and inverted-L groups. Mechanically, adding 1 bicortical positional screw in the retromolar region in the miniplate technique may achieve the same stabilization offered by inverted-L fixation for mandibular sagittal split ramus osteotomy setback surgery in vitro. Copyright © 2012 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  8. Hierarchically 3D assembled strontium titanate nanomaterials for water splitting application

    NASA Astrophysics Data System (ADS)

    Moniruddin, Md; Afroz, Khurshida; Shabdan, Yerkin; Bizri, Baraa; Nuraje, Nurxat

    2017-10-01

    Water splitting is an important technique to store solar energy in the simple form of chemical energy, such as hydrogen. Strontium titanate (SrTiO3) is one of the most promising photocatalysts to produce hydrogen gas from water splitting. In this research, an electrospinning technique in combination with sol-gel method was developed to synthesize 3D porous SrTiO3 nanostructures. Different crystallite sizes of SrTiO3-nanofibers (STO-NFs) were produced by varying the synthesis parameters including precursor concentration and calcination temperature. The synthesized nanofibers were characterized using DSC, TGA, XRD, SEM, and TEM. The crystallite size of STO-NFs decreases with increasing precursor concentration (3.03-15.78 vol.%) and gradually increases as the calcination temperature increases within the range of 600-800 °C. The photocatalytic activity of different STO-NFs (based on crystallite size) was also evaluated by the amount of H2 production from water splitting under UV irradiation. The H2 evolution study demonstrated that the photocatalytic activity of the STO-NFs strongly depends on the crystallite size of the nanofibers, precursor concentration, and calcination temperature. The H2 production rate increases with increasing crystallite size and temperature, whereas it decreases with increasing precursor concentration. The photocatalytic performance of the STO-NFs was also compared with the commercial SrTiO3 nanoparticles (STO-NPs) after Pt addition as a cocatalyst, where the synthesized nanofibers showed 2 times higher H2 production rate (1.14 mmol/g-h) than that of the nanoparticles. This synthesis technique provides a good example to produce other inorganic photocatalytic 3D porous structure materials.

  9. Retest Reliability of the Rosenzweig Picture-Frustration Study and Similar Semiprojective Techniques

    ERIC Educational Resources Information Center

    Rosenzweig, Saul; And Others

    1975-01-01

    The research dealing with the reliability of the Rosenzweig Picture-Frustration Study is surveyed. Analysis of various split-half, and retest procedures are reviewed and their relative effectiveness evaluated. Reliability measures as applied to projective techniques in general are discussed. (Author/DEP)

  10. Flagged uniform particle splitting for variance reduction in proton and carbon ion track-structure simulations

    NASA Astrophysics Data System (ADS)

    Ramos-Méndez, José; Schuemann, Jan; Incerti, Sebastien; Paganetti, Harald; Schulte, Reinhard; Faddegon, Bruce

    2017-08-01

    Flagged uniform particle splitting was implemented with two methods to improve the computational efficiency of Monte Carlo track structure simulations with TOPAS-nBio by enhancing the production of secondary electrons in ionization events. In method 1 the Geant4 kernel was modified. In method 2 Geant4 was not modified. In both methods a unique flag number assigned to each new split electron was inherited by its progeny, permitting reclassification of the split events as if produced by independent histories. Computational efficiency and accuracy were evaluated for simulations of 0.5-20 MeV protons and 1-20 MeV u-1 carbon ions for three endpoints: (1) mean of the ionization cluster size distribution, (2) mean number of DNA single-strand breaks (SSBs) and double-strand breaks (DSBs) classified with DBSCAN, and (3) mean number of SSBs and DSBs classified with a geometry-based algorithm. For endpoint (1), simulation efficiency was 3 times lower when splitting electrons generated by direct ionization events of primary particles than when splitting electrons generated by the first ionization events of secondary electrons. The latter technique was selected for further investigation. The following results are for method 2, with relative efficiencies about 4.5 times lower for method 1. For endpoint (1), relative efficiency at 128 split electrons approached maximum, increasing with energy from 47.2  ±  0.2 to 66.9  ±  0.2 for protons, decreasing with energy from 51.3  ±  0.4 to 41.7  ±  0.2 for carbon. For endpoint (2), relative efficiency increased with energy, from 20.7  ±  0.1 to 50.2  ±  0.3 for protons, 15.6  ±  0.1 to 20.2  ±  0.1 for carbon. For endpoint (3) relative efficiency increased with energy, from 31.0  ±  0.2 to 58.2  ±  0.4 for protons, 23.9  ±  0.1 to 26.2  ±  0.2 for carbon. Simulation results with and without splitting agreed within 1% (2 standard deviations) for endpoints (1) and (2), within 2% (1 standard deviation) for endpoint (3). In conclusion, standard particle splitting variance reduction techniques can be successfully implemented in Monte Carlo track structure codes.

  11. Single-phase Whole-body 64-MDCT Split-bolus Protocol for Pediatric Oncology: Diagnostic Efficacy and Dose Radiation.

    PubMed

    Scialpi, Michele; Schiavone, Raffaele; D'Andrea, Alfredo; Palumbo, Isabella; Magli, Michelle; Gravante, Sabrina; Falcone, Giuseppe; De Filippi, Claudio; Manganaro, Lucia; Palumbo, Barbara

    2015-05-01

    To evaluate the image quality and the diagnostic efficacy by single-phase whole-body 64-slice multidetector CT (MDCT) for pediatric oncology. Chest-abdomen-pelvis CT examinations with single-phase split-bolus technique were evaluated for T: detection and delineation of primary tumor (assessment of the extent of the lesion to neighboring tissues), N: regional lymph nodes and M: distant metastasis. Quality scores (5-point scale) were assessed by two radiologists on parenchymal and vascular enhancement. Accurate TNM staging in term of detection and delineation of primary tumor, regional lymph nodes and distant metastasis was obtained in all cases. On the image quality and severity artifact, the Kappa value for the interobserver agreement measure obtained from the analysis was 0.754, (p<0.001), characterizing a very good agreement between observers. Single-pass total body CT split-bolus technique reached the highest overall image quality and an accurate TNM staging in pediatric patients with cancer. Copyright© 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  12. Use of an Electrochemical Split Cell Technique to Evaluate the Influence of Shewanella oneidensis Activities on Corrosion of Carbon Steel.

    PubMed

    Miller, Robert Bertram; Sadek, Anwar; Rodriguez, Alvaro; Iannuzzi, Mariano; Giai, Carla; Senko, John M; Monty, Chelsea N

    2016-01-01

    Microbially induced corrosion (MIC) is a complex problem that affects various industries. Several techniques have been developed to monitor corrosion and elucidate corrosion mechanisms, including microbiological processes that induce metal deterioration. We used zero resistance ammetry (ZRA) in a split chamber configuration to evaluate the effects of the facultatively anaerobic Fe(III) reducing bacterium Shewanella oneidensis MR-1 on the corrosion of UNS G10180 carbon steel. We show that activities of S. oneidensis inhibit corrosion of steel with which that organism has direct contact. However, when a carbon steel coupon in contact with S. oneidensis was electrically connected to a second coupon that was free of biofilm (in separate chambers of the split chamber assembly), ZRA-based measurements indicated that current moved from the S. oneidensis-containing chamber to the cell-free chamber. This electron transfer enhanced the O2 reduction reaction on the coupon deployed in the cell free chamber, and consequently, enhanced oxidation and corrosion of that electrode. Our results illustrate a novel mechanism for MIC in cases where metal surfaces are heterogeneously covered by biofilms.

  13. Nonlinear PP and PS joint inversion based on the exact Zoeppritz equations: a two-stage procedure

    NASA Astrophysics Data System (ADS)

    Zhi, Lixia; Chen, Shuangquan; Song, Baoshan; Li, Xiang-yang

    2018-04-01

    S-velocity and density are very important parameters in distinguishing lithology and estimating other petrophysical properties. A reliable estimate of S-velocity and density is very difficult to obtain, even from long-offset gather data. Joint inversion of PP and PS data provides a promising strategy for stabilizing and improving the results of inversion in estimating elastic parameters and density. For 2D or 3D inversion, the trace-by-trace strategy is still the most widely used method although it often suffers from a lack of clarity because of its high efficiency, which is due to parallel computing. This paper describes a two-stage inversion method for nonlinear PP and PS joint inversion based on the exact Zoeppritz equations. There are several advantages for our proposed methods as follows: (1) Thanks to the exact Zoeppritz equation, our joint inversion method is applicable for wide angle amplitude-versus-angle inversion; (2) The use of both P- and S-wave information can further enhance the stability and accuracy of parameter estimation, especially for the S-velocity and density; (3) The two-stage inversion procedure proposed in this paper can achieve a good compromise between efficiency and precision. On the one hand, the trace-by-trace strategy used in the first stage can be processed in parallel so that it has high computational efficiency. On the other hand, to deal with the indistinctness of and undesired disturbances to the inversion results obtained from the first stage, we apply the second stage—total variation (TV) regularization. By enforcing spatial and temporal constraints, the TV regularization stage deblurs the inversion results and leads to parameter estimation with greater precision. Notably, the computation consumption of the TV regularization stage can be ignored compared to the first stage because it is solved using the fast split Bregman iterations. Numerical examples using a well log and the Marmousi II model show that the proposed joint inversion is a reliable method capable of accurately estimating the density parameter as well as P-wave velocity and S-wave velocity, even when the seismic data is noisy with signal-to-noise ratio of 5.

  14. Image-Guided Internal Fixation of an Oblique Sagittal Split Fracture of C1 Lateral Mass with Motion Preservation: A Technical Report

    PubMed Central

    Malcolm, James G; Johnson, Andrew K

    2017-01-01

    A sagittal split fracture of the C1 lateral mass is an unstable subtype of C1 fractures and has a high propensity for developing late deformities and pain with nonoperative management. A primary internal fixation of this type of fracture has been recently described with good clinical outcomes and preservation of motion. We present a modified technique of primary internal fixation using an obliquely inserted C1 lag screw with imaging guidance. We successfully treated a 55-year-old woman with a unilateral C1 oblique sagittal split fracture who failed nonoperative management. Technical nuances are discussed with a review of pertinent literature. PMID:28948116

  15. An Empirical Study of Re-sampling Techniques as a Method for Improving Error Estimates in Split-plot Designs

    DTIC Science & Technology

    2010-03-01

    sufficient replications often lead to models that lack precision in error estimation and thus imprecision in corresponding conclusions. This work develops...v Preface This work is dedicated to all who gave and continue to give in order for me to achieve some semblance of success. Benjamin M. Lee vi...develop, examine and test methodologies for an- alyzing test results from split-plot designs. In particular, this work determines the applicability

  16. The splitting and oscillator strengths for the 2S/2/S-2p/2/P/0/ doublet in lithium-like sulfur. [during Skylab observed solar flares

    NASA Technical Reports Server (NTRS)

    Pegg, D. J.; Forester, J. P.; Elston, S. B.; Griffin, P. M.; Peterson, R. S.; Thoe, R. S.; Vane, C. R.; Sellin, I. A.; Groeneveld, K.-O.

    1977-01-01

    The beam-foil technique has been used to study the 2S(2)S-2p(2)P(0) doublet in S XIV. The results confirm the doublet splitting measured aboard Skylab during solar flare events. In addition, the oscillator strengths for the resonance transitions comprising this doublet have been measured and found to agree well with recent relativistic f-value calculations.

  17. A higher-order split-step Fourier parabolic-equation sound propagation solution scheme.

    PubMed

    Lin, Ying-Tsong; Duda, Timothy F

    2012-08-01

    A three-dimensional Cartesian parabolic-equation model with a higher-order approximation to the square-root Helmholtz operator is presented for simulating underwater sound propagation in ocean waveguides. The higher-order approximation includes cross terms with the free-space square-root Helmholtz operator and the medium phase speed anomaly. It can be implemented with a split-step Fourier algorithm to solve for sound pressure in the model. Two idealized ocean waveguide examples are presented to demonstrate the performance of this numerical technique.

  18. Enhanced microwave characterisation technique for cryogenic temperatures

    NASA Astrophysics Data System (ADS)

    Smuk, J. W.; Stubbs, M. G.; Wight, J. S.

    1990-12-01

    A real-time technique to de-embed broadband S-parameter measurements of MIC/MMIC devices at temperatures down to 13 K is presented. Exceptional accuracy is obtained by using a split-block test fixture and the TRL calibration technique at cryogenic temperatures for the first time. The repeatability of the technique and the measurement of a transmission line at 297 K and 77 K are demonstrated from 0.1 GHz to 20 GHz.

  19. External tissue expansion for difficult wounds using a simple cost effective technique.

    PubMed

    Nandhagopal, Vijayaraghavan; Chittoria, Ravi Kumar; Mohapatra, Devi Prasad; Thiruvoth, Friji Meethale; Sivakumar, Dinesh Kumar; Ashokan, Arjun

    2015-01-01

    To study and discuss role of external tissue expansion and wound closure (ETEWC) technique using hooks and rubber bands. The present study is a retrospective analysis of nine cases of wounds of different aetiology where ETEWC technique was applied using hooks and rubber bands. All the wounds in the study healed completely without split thickness skin graft (SSG) or flap. ETEWC technique using hooks and rubber bands is a cost-effective technique which can be used for wound closure without SSG or flap.

  20. Activation of different split functionalities upon re-association of RNA-DNA hybrids

    PubMed Central

    Afonin, Kirill A.; Viard, Mathias; Martins, Angelica N.; Lockett, Stephen J.; Maciag, Anna E.; Freed, Eric O.; Heldman, Eliahu; Jaeger, Luc; Blumenthal, Robert; Shapiro, Bruce A.

    2013-01-01

    Split-protein systems, an approach that relies on fragmentation of proteins with their further conditional re-association to form functional complexes, are increasingly used for various biomedical applications. This approach offers tight control of the protein functions and improved detection sensitivity. Here we show a similar technique based on a pair of RNA-DNA hybrids that can be generally used for triggering different split functionalities. Individually, each hybrid is inactive but when two cognate hybrids re-associate, different functionalities are triggered inside mammalian cells. As a proof of concept this work is mainly focused on activation of RNA interference; however the release of other functionalities (resonance energy transfer and RNA aptamer) is also shown. Furthermore, in vivo studies demonstrate a significant uptake of the hybrids by tumors together with specific gene silencing. This split-functionality approach presents a new route in the development of “smart” nucleic acids based nanoparticles and switches for various biomedical applications. PMID:23542902

  1. Surgical correction of cryptotia combined with an ultra-delicate split-thickness skin graft in continuity with a full-thickness skin rotation flap.

    PubMed

    Yu, Xiaobo; Yang, Qinghua; Jiang, Haiyue; Pan, Bo; Zhao, Yanyong; Lin, Lin

    2017-11-01

    Cryptotia is a common congenital ear deformity in Asian populations. In cryptotia, a portion of the upper ear is hidden and fixed in a pocket of the skin of the mastoid. Here we describe our method for cryptotia correction by using an ultra-delicate split-thickness skin graft in continuity with a full-thickness skin rotation flap. We developed a new method for correcting cryptotia by using an ultra-delicate split-thickness skin graft in continuity with a full-thickness skin rotation flap. Following ear release, the full-thickness skin rotation flap is rotated into the defect, and the donor site is covered with an ultra-delicate split-thickness skin graft raised in continuity with the flap. All patients exhibited satisfactory release of cryptotia. No cases involved partial or total flap necrosis, and post-operative outcomes using this new technique for cryptotia correction have been more than satisfactory. Our method of using an ultra-delicate split-thickness skin graft in continuity with a full-thickness skin rotation flap to correct cryptotia is simple and reliable. Copyright © 2017 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  2. The Use of Split-Thickness Skin Grafts on Diabetic Foot Ulcerations: A Literature Review

    PubMed Central

    McCartan, Brant; Dinh, Thanh

    2012-01-01

    Diabetic foot ulcerations are historically difficult to treat despite advanced therapeutic modalities. There are numerous modalities described in the literature ranging from noninvasive topical wound care to more invasive surgical procedures such as primary closure, skin flaps, and skin grafting. While skin grafting provides faster time to closure with a single treatment compared to traditional topical wound treatments, the potential risks of donor site morbidity and poor wound healing unique to the diabetic state have been cited as a contraindication to its widespread use. In order to garner clarity on this issue, a literature review was undertaken on the use of split-thickness skin grafts on diabetic foot ulcers. Search of electronic databases yielded four studies that reported split-thickness skin grafts as definitive means of closure. In addition, several other studies employed split-thickness skin grafts as an adjunct to a treatment that was only partially successful or used to fill in the donor site of another plastic surgery technique. When used as the primary closure on optimized diabetic foot ulcerations, split-thickness skin grafts are 78% successful at closing 90% of the wound by eight weeks. PMID:22666573

  3. Grid generation for the solution of partial differential equations

    NASA Technical Reports Server (NTRS)

    Eiseman, Peter R.; Erlebacher, Gordon

    1989-01-01

    A general survey of grid generators is presented with a concern for understanding why grids are necessary, how they are applied, and how they are generated. After an examination of the need for meshes, the overall applications setting is established with a categorization of the various connectivity patterns. This is split between structured grids and unstructured meshes. Altogether, the categorization establishes the foundation upon which grid generation techniques are developed. The two primary categories are algebraic techniques and partial differential equation techniques. These are each split into basic parts, and accordingly are individually examined in some detail. In the process, the interrelations between the various parts are accented. From the established background in the primary techniques, consideration is shifted to the topic of interactive grid generation and then to adaptive meshes. The setting for adaptivity is established with a suitable means to monitor severe solution behavior. Adaptive grids are considered first and are followed by adaptive triangular meshes. Then the consideration shifts to the temporal coupling between grid generators and PDE-solvers. To conclude, a reflection upon the discussion, herein, is given.

  4. Grid generation for the solution of partial differential equations

    NASA Technical Reports Server (NTRS)

    Eiseman, Peter R.; Erlebacher, Gordon

    1987-01-01

    A general survey of grid generators is presented with a concern for understanding why grids are necessary, how they are applied, and how they are generated. After an examination of the need for meshes, the overall applications setting is established with a categorization of the various connectivity patterns. This is split between structured grids and unstructured meshes. Altogether, the categorization establishes the foundation upon which grid generation techniques are developed. The two primary categories are algebraic techniques and partial differential equation techniques. These are each split into basic parts, and accordingly are individually examined in some detail. In the process, the interrelations between the various parts are accented. From the established background in the primary techniques, consideration is shifted to the topic of interactive grid generation and then to adaptive meshes. The setting for adaptivity is established with a suitable means to monitor severe solution behavior. Adaptive grids are considered first and are followed by adaptive triangular meshes. Then the consideration shifts to the temporal coupling between grid generators and PDE-solvers. To conclude, a reflection upon the discussion, herein, is given.

  5. Micro- and nano-scale optical devices for high density photonic integrated circuits at near-infrared wavelengths

    NASA Astrophysics Data System (ADS)

    Chatterjee, Rohit

    In this research work, we explore fundamental silicon-based active and passive photonic devices that can be integrated together to form functional photonic integrated circuits. The devices which include power splitters, switches and lenses are studied starting from their physics, their design and fabrication techniques and finally from an experimental standpoint. The experimental results reveal high performance devices that are compatible with standard CMOS fabrication processes and can be easily integrated with other devices for near infrared telecom applications. In Chapter 2, a novel method for optical switching using nanomechanical proximity perturbation technique is described and demonstrated. The method which is experimentally demonstrated employs relatively low powers, small chip footprint and is compatible with standard CMOS fabrication processes. Further, in Chapter 3, this method is applied to develop a hitless bypass switch aimed at solving an important issue in current wavelength division multiplexing systems namely hitless switching of reconfigurable optical add drop multiplexers. Experimental results are presented to demonstrate the application of the nanomechanical proximity perturbation technique to practical situations. In Chapter 4, a fundamental photonic component namely the power splitter is described. Power splitters are important components for any photonic integrated circuits because they help split the power from a single light source to multiple devices on the same chip so that different operations can be performed simultaneously. The power splitters demonstrated in this chapter are based on multimode interference principles resulting in highly compact low loss and highly uniform power splitting to split the power of the light from a single channel to two and four channels. These devices can further be scaled to achieve higher order splitting such as 1x16 and 1x32 power splits. Finally in Chapter 5 we overcome challenges in device fabrication and measurement techniques to demonstrate for the first time a "superlens" for the technologically important near infrared wavelength ranges with the opportunity to scale down further to visible wavelengths. The observed resolution is 0.47lambda, clearly smaller than the diffraction limit of 0.61lambda and is supported by detailed theoretical analyses and comprehensive numerical simulations. Importantly, we clearly show for the first time this subdiffraction limit imaging is due to the resonant excitation of surface slab modes, permitting amplification of evanescent waves. The demonstrated "superlens" has the largest figure of merit ever reported till date both theoretically and experimentally. The techniques and devices described in this thesis can be further applied to develop new devices with different functionalities. In Chapter 6 we describe two examples using these ideas. First, we experimentally demonstrate the use of the nanomechanical proximity perturbation technique to develop a phase retarder for on-chip all state polarization control. Next, we use the negative refraction photonic crystals described in Chapter 5 to achieve a special kind of bandgap called the zero-n¯ bandgap having unique properties.

  6. Design and fabrication of cascaded dichromate gelatin holographic filters for spectrum-splitting PV systems

    NASA Astrophysics Data System (ADS)

    Wu, Yuechen; Chrysler, Benjamin; Kostuk, Raymond K.

    2018-01-01

    The technique of designing, optimizing, and fabricating broadband volume transmission holograms using dichromate gelatin (DCG) is summarized for solar spectrum-splitting applications. The spectrum-splitting photovoltaic (PV) system uses a series of single-bandgap PV cells that have different spectral conversion efficiency properties to more fully utilize the solar spectrum. In such a system, one or more high-performance optical filters are usually required to split the solar spectrum and efficiently send them to the corresponding PV cells. An ideal spectral filter should have a rectangular shape with sharp transition wavelengths. A methodology of designing and modeling a transmission DCG hologram using coupled wave analysis for different PV bandgap combinations is described. To achieve a broad diffraction bandwidth and sharp cutoff wavelength, a cascaded structure of multiple thick holograms is described. A search algorithm is then developed to optimize both single- and two-layer cascaded holographic spectrum-splitting elements for the best bandgap combinations of two- and three-junction spectrum-splitting photovoltaic (SSPV) systems illuminated under the AM1.5 solar spectrum. The power conversion efficiencies of the optimized systems are found to be 42.56% and 48.41%, respectively, using the detailed balance method, and show an improvement compared with a tandem multijunction system. A fabrication method for cascaded DCG holographic filters is also described and used to prototype the optimized filter for the three-junction SSPV system.

  7. Current status and perspectives in split liver transplantation

    PubMed Central

    Lauterio, Andrea; Di Sandro, Stefano; Concone, Giacomo; De Carlis, Riccardo; Giacomoni, Alessandro; De Carlis, Luciano

    2015-01-01

    Growing experience with the liver splitting technique and favorable results equivalent to those of whole liver transplant have led to wider application of split liver transplantation (SLT) for adult and pediatric recipients in the last decade. Conversely, SLT for two adult recipients remains a challenging surgical procedure and outcomes have yet to improve. Differences in organ shortages together with religious and ethical issues related to cadaveric organ donation have had an impact on the worldwide distribution of SLT. Despite technical refinements and a better understanding of the complex liver anatomy, SLT remains a technically and logistically demanding surgical procedure. This article reviews the surgical and clinical advances in this field of liver transplantation focusing on the role of SLT and the issues that may lead a further expansion of this complex surgical procedure. PMID:26494957

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dernotte, Jeremie; Dec, John E.; Ji, Chunsheng

    A detailed understanding of the various factors affecting the trends in gross-indicated thermal efficiency with changes in key operating parameters has been carried out, applied to a one-liter displacement single-cylinder boosted Low-Temperature Gasoline Combustion (LTGC) engine. This work systematically investigates how the supplied fuel energy splits into the following four energy pathways: gross-indicated thermal efficiency, combustion inefficiency, heat transfer and exhaust losses, and how this split changes with operating conditions. Additional analysis is performed to determine the influence of variations in the ratio of specific heat capacities (γ) and the effective expansion ratio, related to the combustion-phasing retard (CA50), onmore » the energy split. Heat transfer and exhaust losses are computed using multiple standard cycle analysis techniques. Furthermore, the various methods are evaluated in order to validate the trends.« less

  9. Use of an Electrochemical Split Cell Technique to Evaluate the Influence of Shewanella oneidensis Activities on Corrosion of Carbon Steel

    PubMed Central

    Miller, Robert Bertram; Sadek, Anwar; Rodriguez, Alvaro; Iannuzzi, Mariano; Giai, Carla; Senko, John M.; Monty, Chelsea N.

    2016-01-01

    Microbially induced corrosion (MIC) is a complex problem that affects various industries. Several techniques have been developed to monitor corrosion and elucidate corrosion mechanisms, including microbiological processes that induce metal deterioration. We used zero resistance ammetry (ZRA) in a split chamber configuration to evaluate the effects of the facultatively anaerobic Fe(III) reducing bacterium Shewanella oneidensis MR-1 on the corrosion of UNS G10180 carbon steel. We show that activities of S. oneidensis inhibit corrosion of steel with which that organism has direct contact. However, when a carbon steel coupon in contact with S. oneidensis was electrically connected to a second coupon that was free of biofilm (in separate chambers of the split chamber assembly), ZRA-based measurements indicated that current moved from the S. oneidensis-containing chamber to the cell-free chamber. This electron transfer enhanced the O2 reduction reaction on the coupon deployed in the cell free chamber, and consequently, enhanced oxidation and corrosion of that electrode. Our results illustrate a novel mechanism for MIC in cases where metal surfaces are heterogeneously covered by biofilms. PMID:26824529

  10. Self-aligned quadruple patterning using spacer on spacer integration optimization for N5

    NASA Astrophysics Data System (ADS)

    Thibaut, Sophie; Raley, Angélique; Mohanty, Nihar; Kal, Subhadeep; Liu, Eric; Ko, Akiteru; O'Meara, David; Tapily, Kandabara; Biolsi, Peter

    2017-04-01

    To meet scaling requirements, the semiconductor industry has extended 193nm immersion lithography beyond its minimum pitch limitation using multiple patterning schemes such as self-aligned double patterning, self-aligned quadruple patterning and litho-etch / litho etch iterations. Those techniques have been declined in numerous options in the last few years. Spacer on spacer pitch splitting integration has been proven to show multiple advantages compared to conventional pitch splitting approach. Reducing the number of pattern transfer steps associated with sacrificial layers resulted in significant decrease of cost and an overall simplification of the double pitch split technique. While demonstrating attractive aspects, SAQP spacer on spacer flow brings challenges of its own. Namely, material set selections and etch chemistry development for adequate selectivities, mandrel shape and spacer shape engineering to improve edge placement error (EPE). In this paper we follow up and extend upon our previous learning and proceed into more details on the robustness of the integration in regards to final pattern transfer and full wafer critical dimension uniformity. Furthermore, since the number of intermediate steps is reduced, one will expect improved uniformity and pitch walking control. This assertion will be verified through a thorough pitch walking analysis.

  11. Iterative methods for 3D implicit finite-difference migration using the complex Padé approximation

    NASA Astrophysics Data System (ADS)

    Costa, Carlos A. N.; Campos, Itamara S.; Costa, Jessé C.; Neto, Francisco A.; Schleicher, Jörg; Novais, Amélia

    2013-08-01

    Conventional implementations of 3D finite-difference (FD) migration use splitting techniques to accelerate performance and save computational cost. However, such techniques are plagued with numerical anisotropy that jeopardises the correct positioning of dipping reflectors in the directions not used for the operator splitting. We implement 3D downward continuation FD migration without splitting using a complex Padé approximation. In this way, the numerical anisotropy is eliminated at the expense of a computationally more intensive solution of a large-band linear system. We compare the performance of the iterative stabilized biconjugate gradient (BICGSTAB) and that of the multifrontal massively parallel direct solver (MUMPS). It turns out that the use of the complex Padé approximation not only stabilizes the solution, but also acts as an effective preconditioner for the BICGSTAB algorithm, reducing the number of iterations as compared to the implementation using the real Padé expansion. As a consequence, the iterative BICGSTAB method is more efficient than the direct MUMPS method when solving a single term in the Padé expansion. The results of both algorithms, here evaluated by computing the migration impulse response in the SEG/EAGE salt model, are of comparable quality.

  12. Zonal Flow Velocimetry in Spherical Couette Flow using Acoustic Modes

    NASA Astrophysics Data System (ADS)

    Adams, Matthew M.; Mautino, Anthony R.; Stone, Douglas R.; Triana, Santiago A.; Lekic, Vedran; Lathrop, Daniel P.

    2015-11-01

    We present studies of spherical Couette flows using the technique of acoustic mode Doppler velocimetry. This technique uses rotational splittings of acoustic modes to infer the azimuthal velocity profile of a rotating flow, and is of special interest in experiments where direct flow visualization is impractical. The primary experimental system consists of a 60 cm diameter outer spherical shell concentric with a 20 cm diameter sphere, with air or nitrogen gas serving as the working fluid. The geometry of the system approximates that of the Earth's core, making these studies geophysically relevant. A turbulent shear flow is established in the system by rotating the inner sphere and outer shell at different rates. Acoustic modes of the fluid volume are excited using a speaker and measured via microphones, allowingdetermination of rotational splittings. Preliminary results comparing observed splittings with those predicted by theory are presented. While the majority of these studies were performed in the 60 cm diameter device using nitrogen gas, some work has also been done looking at acoustic modes in the 3 m diameter liquid sodium spherical Couette experiment. Prospects for measuring zonal velocity profiles in a wide variety of experiments are discussed.

  13. A numerical model for predicting crack path and modes of damage in unidirectional metal matrix composites

    NASA Technical Reports Server (NTRS)

    Bakuckas, J. G.; Tan, T. M.; Lau, A. C. W.; Awerbuch, J.

    1993-01-01

    A finite element-based numerical technique has been developed to simulate damage growth in unidirectional composites. This technique incorporates elastic-plastic analysis, micromechanics analysis, failure criteria, and a node splitting and node force relaxation algorithm to create crack surfaces. Any combination of fiber and matrix properties can be used. One of the salient features of this technique is that damage growth can be simulated without pre-specifying a crack path. In addition, multiple damage mechanisms in the forms of matrix cracking, fiber breakage, fiber-matrix debonding and plastic deformation are capable of occurring simultaneously. The prevailing failure mechanism and the damage (crack) growth direction are dictated by the instantaneous near-tip stress and strain fields. Once the failure mechanism and crack direction are determined, the crack is advanced via the node splitting and node force relaxation algorithm. Simulations of the damage growth process in center-slit boron/aluminum and silicon carbide/titanium unidirectional specimens were performed. The simulation results agreed quite well with the experimental observations.

  14. 21 CFR 866.5080 - Alpha-1-antichymotrypsin immunological test system.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... immunochemical techniques alpha-1-antichymotrypsin (a protein) in serum, other body fluids, and tissues. Alpha-1-antichymotrypsin helps protect tissues against proteolytic (protein-splitting) enzymes released during infection...

  15. A Novel Iterative Scheme for the Very Fast and Accurate Solution of Non-LTE Radiative Transfer Problems

    NASA Astrophysics Data System (ADS)

    Trujillo Bueno, J.; Fabiani Bendicho, P.

    1995-12-01

    Iterative schemes based on Gauss-Seidel (G-S) and optimal successive over-relaxation (SOR) iteration are shown to provide a dramatic increase in the speed with which non-LTE radiation transfer (RT) problems can be solved. The convergence rates of these new RT methods are identical to those of upper triangular nonlocal approximate operator splitting techniques, but the computing time per iteration and the memory requirements are similar to those of a local operator splitting method. In addition to these properties, both methods are particularly suitable for multidimensional geometry, since they neither require the actual construction of nonlocal approximate operators nor the application of any matrix inversion procedure. Compared with the currently used Jacobi technique, which is based on the optimal local approximate operator (see Olson, Auer, & Buchler 1986), the G-S method presented here is faster by a factor 2. It gives excellent smoothing of the high-frequency error components, which makes it the iterative scheme of choice for multigrid radiative transfer. This G-S method can also be suitably combined with standard acceleration techniques to achieve even higher performance. Although the convergence rate of the optimal SOR scheme developed here for solving non-LTE RT problems is much higher than G-S, the computing time per iteration is also minimal, i.e., virtually identical to that of a local operator splitting method. While the conventional optimal local operator scheme provides the converged solution after a total CPU time (measured in arbitrary units) approximately equal to the number n of points per decade of optical depth, the time needed by this new method based on the optimal SOR iterations is only √n/2√2. This method is competitive with those that result from combining the above-mentioned Jacobi and G-S schemes with the best acceleration techniques. Contrary to what happens with the local operator splitting strategy currently in use, these novel methods remain effective even under extreme non-LTE conditions in very fine grids.

  16. Production of arrays of chemically distinct nanolitre plugs via repeated splitting in microfluidic devices.

    PubMed

    Adamson, David N; Mustafi, Debarshi; Zhang, John X J; Zheng, Bo; Ismagilov, Rustem F

    2006-09-01

    This paper reports a method for the production of arrays of nanolitre plugs with distinct chemical compositions. One of the primary constraints on the use of plug-based microfluidics for large scale biological screening is the difficulty of fabricating arrays of chemically distinct plugs on the nanolitre scale. Here, using microfluidic devices with several T-junctions linked in series, a single input array of large (approximately 320 nL) plugs was split to produce 16 output arrays of smaller (approximately 20 nL) plugs; the composition and configuration of these arrays were identical to that of the input. This paper shows how the passive break-up of plugs in T-junction microchannel geometries can be used to produce a set of smaller-volume output arrays useful for chemical screening from a single large-volume array. A simple theoretical description is presented to describe splitting as a function of the Capillary number, the capillary pressure, the total pressure difference across the channel, and the geometric fluidic resistance. By accounting for these considerations, plug coalescence and plug-plug contamination can be eliminated from the splitting process and the symmetry of splitting can be preserved. Furthermore, single-outlet splitting devices were implemented with both valve- and volume-based methods for coordinating the release of output arrays. Arrays of plugs containing commercial sparse matrix screens were obtained from the presented splitting method and these arrays were used in protein crystallization trials. The techniques presented in this paper may facilitate the implementation of high-throughput chemical and biological screening.

  17. Detection of membrane protein-protein interaction in planta based on dual-intein-coupled tripartite split-GFP association.

    PubMed

    Liu, Tzu-Yin; Chou, Wen-Chun; Chen, Wei-Yuan; Chu, Ching-Yi; Dai, Chen-Yi; Wu, Pei-Yu

    2018-05-01

    Despite the great interest in identifying protein-protein interactions (PPIs) in biological systems, only a few attempts have been made at large-scale PPI screening in planta. Unlike biochemical assays, bimolecular fluorescence complementation allows visualization of transient and weak PPIs in vivo at subcellular resolution. However, when the non-fluorescent fragments are highly expressed, spontaneous and irreversible self-assembly of the split halves can easily generate false positives. The recently developed tripartite split-GFP system was shown to be a reliable PPI reporter in mammalian and yeast cells. In this study, we adapted this methodology, in combination with the β-estradiol-inducible expression cassette, for the detection of membrane PPIs in planta. Using a transient expression assay by agroinfiltration of Nicotiana benthamiana leaves, we demonstrate the utility of the tripartite split-GFP association in plant cells and affirm that the tripartite split-GFP system yields no spurious background signal even with abundant fusion proteins readily accessible to the compartments of interaction. By validating a few of the Arabidopsis PPIs, including the membrane PPIs implicated in phosphate homeostasis, we proved the fidelity of this assay for detection of PPIs in various cellular compartments in planta. Moreover, the technique combining the tripartite split-GFP association and dual-intein-mediated cleavage of polyprotein precursor is feasible in stably transformed Arabidopsis plants. Our results provide a proof-of-concept implementation of the tripartite split-GFP system as a potential tool for membrane PPI screens in planta. © 2018 The Authors The Plant Journal © 2018 John Wiley & Sons Ltd.

  18. An implicit flux-split algorithm to calculate hypersonic flowfields in chemical equilibrium

    NASA Technical Reports Server (NTRS)

    Palmer, Grant

    1987-01-01

    An implicit, finite-difference, shock-capturing algorithm that calculates inviscid, hypersonic flows in chemical equilibrium is presented. The flux vectors and flux Jacobians are differenced using a first-order, flux-split technique. The equilibrium composition of the gas is determined by minimizing the Gibbs free energy at every node point. The code is validated by comparing results over an axisymmetric hemisphere against previously published results. The algorithm is also applied to more practical configurations. The accuracy, stability, and versatility of the algorithm have been promising.

  19. Alternating Direction Implicit (ADI) schemes for a PDE-based image osmosis model

    NASA Astrophysics Data System (ADS)

    Calatroni, L.; Estatico, C.; Garibaldi, N.; Parisotto, S.

    2017-10-01

    We consider Alternating Direction Implicit (ADI) splitting schemes to compute efficiently the numerical solution of the PDE osmosis model considered by Weickert et al. in [10] for several imaging applications. The discretised scheme is shown to preserve analogous properties to the continuous model. The dimensional splitting strategy traduces numerically into the solution of simple tridiagonal systems for which standard matrix factorisation techniques can be used to improve upon the performance of classical implicit methods, even for large time steps. Applications to the shadow removal problem are presented.

  20. En bloc resection of huge cemento-ossifying fibroma of mandible: avoiding lower lip split incision.

    PubMed

    Ayub, Tahera; Katpar, Shahjahan; Shafique, Salman; Mirza, Talat

    2011-05-01

    Cemento-ossifying Fibroma (COF) is an osteogenic benign neoplasm affecting the jaws and other craniofacial bones. It commonly presents as a progressively slow growing pathology, which can sometimes attain an enormous size, causing facial deformity. A case of a huge cemento-ossifying fibroma, appearing as a mandibular dumbell tumour in a male patient is documented, which caused massive bone destruction and deformity. It was surgically removed by performing en bloc resection of mandible avoiding the splitting of lower lip incision technique, thereby maintaining his normal facial appearance.

  1. An Operator-Integration-Factor Splitting (OIFS) method for Incompressible Flows in Moving Domains

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Patel, Saumil S.; Fischer, Paul F.; Min, Misun

    In this paper, we present a characteristic-based numerical procedure for simulating incompressible flows in domains with moving boundaries. Our approach utilizes an operator-integration-factor splitting technique to help produce an effcient and stable numerical scheme. Using the spectral element method and an arbitrary Lagrangian-Eulerian formulation, we investigate flows where the convective acceleration effects are non-negligible. Several examples, ranging from laminar to turbulent flows, are considered. Comparisons with a standard, semi-implicit time-stepping procedure illustrate the improved performance of the scheme.

  2. NREL to Lead New Consortium to Develop Advanced Water Splitting Materials

    Science.gov Websites

    said. "Our research strategy integrates computational tools and modeling, material synthesis needs, such as high-throughput synthesis techniques and auxiliary component design. HydroGEN is the

  3. Vistas in applied mathematics: Numerical analysis, atmospheric sciences, immunology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Balakrishnan, A.V.; Dorodnitsyn, A.A.; Lions, J.L.

    1986-01-01

    Advances in the theory and application of numerical modeling techniques are discussed in papers contributed, primarily by Soviet scientists, on the occasion of the 60th birthday of Gurii I. Marchuk. Topics examined include splitting techniques for computations of industrial flows, the mathematical foundations of the k-epsilon turbulence model, splitting methods for the solution of the incompressible Navier-Stokes equations, the approximation of inhomogeneous hyperbolic boundary-value problems, multigrid methods, and the finite-element approximation of minimal surfaces. Consideration is given to dynamic modeling of moist atmospheres, satellite observations of the earth radiation budget and the problem of energy-active ocean regions, a numerical modelmore » of the biosphere for use with GCMs, and large-scale modeling of ocean circulation. Also included are several papers on modeling problems in immunology.« less

  4. Progress Towards a New Technique for Measuring Local Electric and Magnetic Field Fluctuations in High Temperature Plasmas

    NASA Astrophysics Data System (ADS)

    Burke, M. G.; Fonck, R. J.; McKee, G. R.; Winz, G. R.

    2017-10-01

    Local measurements of electrostatic and magnetic turbulence in fusion grade plasmas is a critical missing component in advancing our understanding of current experiments and validating nonlinear turbulence simulations. A novel diagnostic for measuring local electric and magnetic field fluctuations (Ẽ and B ) is being developed to address this need. It employs high-speed measurements of the spectral linewidth and/or line intensities of the Motional Stark Effect split neutral beam emission. This emission is split into several spectral components, with the amount of splitting being proportional to local magnetic and electric fields at the emission site. High spectral resolution ( 0.025 nm), high throughput ( 0.01 cm2str), and high speed (f 250 kHz) are required for the measurement of fast changes in the MSE spectrum. Spatial heterodyne spectroscopy (SHS) techniques coupled to a CMOS detector can meet these demands. A prototype SHS has been deployed to DIII-D for initial testing in the tokamak environment, SNR evaluation, and neutral beam efficacy. In addition, design studies of the SHS interferogram are ongoing to further optimize the measurement technique. One major contributor to loss of fringe contrast is line broadening arising from employing a large collection lens. This broadening can be mitigated by making the lens at the tokamak wall optically conjugate with the interference fringes image field. Work supported by US DOE Grant DE-FG02-89ER53296.

  5. [Osteosynthesis in the Surgical Treatment of Prognathism: State of The Art].

    PubMed

    Durão, Nuno; Amarante, José

    2017-03-31

    Prognathism is a common skeletal facial abnormality, associated with class III malocclusion, often with repercussions in quality of life. In addition to orthodontic treatment, sagittal split ramus osteotomy is the most common technique for its correction, and segment osteosynthesis is an important element of the post-surgical outcome. A search for relevant literature was conducted in the PubMed/MEDLINE database and in other relevant sources. The stability of different fixation methods, their repercussions on inferior alveolar nerve lesions, and the type of material are among the most researched subjects. Recent research about the type of osteosynthesis applied in the sagittal split ramus osteotomy for mandibular setback is discussed. Miniplates appear to be the better option for fixation of sagittal split osteotomy for mandibular setback. Bioabsorbable osteosynthesis may be an acceptable alternative to titanium.

  6. Protein subcellular localization assays using split fluorescent proteins

    DOEpatents

    Waldo, Geoffrey S [Santa Fe, NM; Cabantous, Stephanie [Los Alamos, NM

    2009-09-08

    The invention provides protein subcellular localization assays using split fluorescent protein systems. The assays are conducted in living cells, do not require fixation and washing steps inherent in existing immunostaining and related techniques, and permit rapid, non-invasive, direct visualization of protein localization in living cells. The split fluorescent protein systems used in the practice of the invention generally comprise two or more self-complementing fragments of a fluorescent protein, such as GFP, wherein one or more of the fragments correspond to one or more beta-strand microdomains and are used to "tag" proteins of interest, and a complementary "assay" fragment of the fluorescent protein. Either or both of the fragments may be functionalized with a subcellular targeting sequence enabling it to be expressed in or directed to a particular subcellular compartment (i.e., the nucleus).

  7. A split-step method to include electron–electron collisions via Monte Carlo in multiple rate equation simulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huthmacher, Klaus; Molberg, Andreas K.; Rethfeld, Bärbel

    2016-10-01

    A split-step numerical method for calculating ultrafast free-electron dynamics in dielectrics is introduced. The two split steps, independently programmed in C++11 and FORTRAN 2003, are interfaced via the presented open source wrapper. The first step solves a deterministic extended multi-rate equation for the ionization, electron–phonon collisions, and single photon absorption by free-carriers. The second step is stochastic and models electron–electron collisions using Monte-Carlo techniques. This combination of deterministic and stochastic approaches is a unique and efficient method of calculating the nonlinear dynamics of 3D materials exposed to high intensity ultrashort pulses. Results from simulations solving the proposed model demonstrate howmore » electron–electron scattering relaxes the non-equilibrium electron distribution on the femtosecond time scale.« less

  8. Copper Oxide Nanograss for Efficient and Stable Photoelectrochemical Hydrogen Production by Water Splitting

    NASA Astrophysics Data System (ADS)

    Borkar, Rajnikant; Dahake, Rashmi; Rayalu, Sadhana; Bansiwal, Amit

    2018-03-01

    A biphasic copper oxide thin film of grass-like appendage morphology is synthesized by two-step electro-deposition method and later investigated for photoelectrochemical (PEC) water splitting for hydrogen production. Further, the thin film was characterized by UV-Visible spectroscopy, x-ray diffraction (XRD), Scanning electron microscopy (SEM) and PEC techniques. The XRD analysis confirms formation of biphasic copper oxide phases, and SEM reveals high surface area grass appendage-like morphology. These grass appendage structures exhibit a high cathodic photocurrent of - 1.44 mAcm-2 at an applied bias of - 0.7 (versus Ag/AgCl) resulting in incident to photon current efficiency (IPCE) of ˜ 10% at 400 nm. The improved light harvesting and charge transport properties of grass appendage structured biphasic copper oxides makes it a potential candidate for PEC water splitting for hydrogen production.

  9. Anisotropy beneath the Southern Pacific - real or apparent?

    NASA Astrophysics Data System (ADS)

    Prasse, Philipp; Thomas, Christine

    2016-04-01

    Anisotropy of the lowermost mantle beneath the South- to Central Pacific is investigated using US-Array receivers and events located near the Tonga-Fiji subduction zones. Differential splitting in three different distance ranges (65° -85° , 90° -110° and >110°) of S-ScS, SKS-S, SKS-Sdiff phases is used. By utilizing differential splitting technique, it was possible to correct for upper mantle, as well as source- and receiver side anisotropy and effectively quantify shear wave splitting originating in the lowermost mantle. Delay times of horizontal (SH) and vertical polarized (SV) shear waves show that predominantly the SH wave is delayed relative to the SV wave. Motivated by the discrepancy in previous Pacific studies investigating the lowermost mantle beneath the Pacific the possibility of isotropic structure producing the observed splitting is tested. Synthetic seismograms are computed, based on various isotropic models and the resulting synthetics are analysed in the same way as the real data. While simple layered models do not produce splitting and therefore apparent anisotropy, models in which the lowermost mantle is represented as a negative gradient in P- and S-wave velocity, produce clear apparent anisotropy. Thus, this study presents a possible alternative way of explaining the structure of the D" region.

  10. Quality of life and female sexual function after skinning vulvectomy with split-thickness skin graft in women with vulvar intraepithelial neoplasia or vulvar Paget disease.

    PubMed

    Lavoué, V; Lemarrec, A; Bertheuil, N; Henno, S; Mesbah, H; Watier, E; Levêque, J; Morcel, K

    2013-12-01

    Vulvar intraepithelial neoplasia (VIN) and vulvar Paget disease are managed with either vulvectomy, destructive treatments (laser, antimitotic drugs) or immunostimulants. All these options are associated with functional complications. The purpose of this study was to evaluate the surgical technique consisting of skinning vulvectomy with split-thickness skin graft, and its effect on overall quality of life and sexual function. A retrospective study was conducted on thirteen patients who underwent skinning vulvectomy with split-thickness skin graft between 1999 and 2009. Overall quality of life and sexual function were assessed with the Medical Outcome Study Short Form 36 (MOS SF-36) and Female Sexual Function Index (FSFI), respectively. The median age of patients was 54 (range: 33-77) years. Three patients had Paget disease and 10 patients had VIN lesions. The excision margins were clear in 46% of cases. The incidence of occult cancer was 31%. The mean follow-up period was 77 (±35) months. Four patients experienced a relapse of their intraepithelial disease. The mean disease-free survival was 58 (±44) months. There was no significant difference in MOS SF-36 scores between the study population and the general population. The patients assessed with the FSFI regained normal sexual function after the surgical procedure. Skinning vulvectomy with split-thickness skin graft is a feasible technique yielding good results in terms of quality of life and sexual function. It enables occult cancer to be diagnosed in patients with VIN or Paget disease. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Retention of a reconstructed nipple using a C-V flap with different layer thicknesses in the C-flap.

    PubMed

    Sowa, Yoshihiro; Itsukage, Sizu; Sakaguchi, Kouichi; Taguchi, Tetsuya; Numajiri, Toshiaki

    2018-04-01

    The C-V flap for nipple reconstruction is now one of standard surgical techniques. But decreased projection is still a problem. In recent years, it has been suggested that projection can be more easily maintained when raising of the C-flap is performed with a split thickness dermis. In this study, we examined whether decrease of projection can be prevented by raising of a C-flap with a split dermis rather than with full dermis. A total of 49 consecutive patients who underwent reconstruction of a nipple using the C-V flap technique were enrolled. The patients included 22 who underwent surgery using a C-flap with a full thickness dermis (Group F), and 27 who underwent surgery with raising of a flap with a split thickness dermis (Group S). The size of the reconstructed nipple was measured at 2 weeks, 6 months and 1 year postoperatively for comparison between Groups F and S. Partial necrosis of the C-flap end occurred in 4 subjects in only Group S. The decrease in projection after 1 year postoperatively in Group S was significantly lower than that in Group F. In contrast, the teat base size in Group F tended to be greater than that in Group S, suggesting a tendency for an expanded base using a flap with a full dermis. Our results indicated that it is recommended to use a C-flap with a split dermis for cases with high projection of the nipple on the contralateral side.

  12. Outcomes for split-thickness skin transplantation in high-risk patients using octenidine.

    PubMed

    Matiasek, J; Djedovic, G; Unger, L; Beck, H; Mattesich, M; Pierer, G; Koller, R; Rieger, U M

    2015-06-01

    Skin transplantation is a commonly used surgical technique; however, the complication rate, including postoperative infection and delayed wound healing due to inefficient perfusion, is significantly higher in patients suffering from comorbidities. Hence, a subsequent repeat procedure is often necessary. In this report, two case studies are presented in which an octenidine-based antiseptic is used with a tie-over dressing (TOD) instead of povidone iodine (PVP-iodine), following a split-thickness skin graft. The two patients selected were deemed to be at high risk of impaired wound healing due to comorbidities. The first patient, a confirmed smoker with diabetes, presented with a nodular melanoma that was resected and covered with a split-thickness skin graft. After 5 days of negative pressure wound therapy as a TOD, in combination with PVP-iodine, the graft became necrotic. A second split-thickness skin graft was performed and an antiseptic regimen with octenidine in combination with the same TOD resulted in a completely healed transplant. The second patient, also a confirmed smoker with diabetes and receiving oral corticosteroid treatment, was diagnosed with a skin necrosis on her leg. Following the split-thickness skin graft, octenidine and TOD were applied. The patient's skin graft completely healed without any adverse events. These two case studies indicate that the combination of octenidine and TOD following split-thickness skin transplantation is safe, well-tolerated and appears to have positive benefits in the reconstruction of defects in patients with impaired wound healing.

  13. Oriented covalent immobilization of antibodies for measurement of intermolecular binding forces between zipper-like contact surfaces of split inteins.

    PubMed

    Sorci, Mirco; Dassa, Bareket; Liu, Hongwei; Anand, Gaurav; Dutta, Amit K; Pietrokovski, Shmuel; Belfort, Marlene; Belfort, Georges

    2013-06-18

    In order to measure the intermolecular binding forces between two halves (or partners) of naturally split protein splicing elements called inteins, a novel thiol-hydrazide linker was designed and used to orient immobilized antibodies specific for each partner. Activation of the surfaces was achieved in one step, allowing direct intermolecular force measurement of the binding of the two partners of the split intein (called protein trans-splicing). Through this binding process, a whole functional intein is formed resulting in subsequent splicing. Atomic force microscopy (AFM) was used to directly measure the split intein partner binding at 1 μm/s between native (wild-type) and mixed pairs of C- and N-terminal partners of naturally occurring split inteins from three cyanobacteria. Native and mixed pairs exhibit similar binding forces within the error of the measurement technique (~52 pN). Bioinformatic sequence analysis and computational structural analysis discovered a zipper-like contact between the two partners with electrostatic and nonpolar attraction between multiple aligned ion pairs and hydrophobic residues. Also, we tested the Jarzynski's equality and demonstrated, as expected, that nonequilibrium dissipative measurements obtained here gave larger energies of interaction as compared with those for equilibrium. Hence, AFM coupled with our immobilization strategy and computational studies provides a useful analytical tool for the direct measurement of intermolecular association of split inteins and could be extended to any interacting protein pair.

  14. The EEG Split Alpha Peak: Phenomenological Origins and Methodological Aspects of Detection and Evaluation.

    PubMed

    Olejarczyk, Elzbieta; Bogucki, Piotr; Sobieszek, Aleksander

    2017-01-01

    Electroencephalographic (EEG) patterns were analyzed in a group of ambulatory patients who ranged in age and sex using spectral analysis as well as Directed Transfer Function, a method used to evaluate functional brain connectivity. We tested the impact of window size and choice of reference electrode on the identification of two or more peaks with close frequencies in the spectral power distribution, so called "split alpha." Together with the connectivity analysis, examination of spatiotemporal maps showing the distribution of amplitudes of EEG patterns allowed for better explanation of the mechanisms underlying the generation of split alpha peaks. It was demonstrated that the split alpha spectrum can be generated by two or more independent and interconnected alpha wave generators located in different regions of the cerebral cortex, but not necessarily in the occipital cortex. We also demonstrated the importance of appropriate reference electrode choice during signal recording. In addition, results obtained using the original data were compared with results obtained using re-referenced data, using average reference electrode and reference electrode standardization techniques.

  15. Improving multiphoton STED nanoscopy with separation of photons by LIfetime Tuning (SPLIT)

    NASA Astrophysics Data System (ADS)

    Coto Hernández, Iván.; Lanzano, Luca; Castello, Marco; Jowett, Nate; Tortarolo, Giorgio; Diaspro, Alberto; Vicidomini, Giuseppe

    2018-02-01

    Stimulated emission depletion (STED) microscopy is a powerful bio-imaging technique since it provides molecular spatial resolution whilst preserving the most important assets of fluorescence microscopy. When combined with twophoton excitation (2PE) microscopy (2PE-STED), the sub-diffraction imaging ability of STED microscopy can be achieved also on thick biological samples. The most straightforward implementation of 2PE-STED microscopy is obtained by introducing a STED beam operating in continuous wave (CW) into a conventional Ti:Sapphire based 2PE microscope (2PE-CW-STED). In this implementation, an effective resolution enhancement is mainly obtained implementing a time-gated detection scheme, which however can drastically reduce the signal-to-noise/background ratio of the final image. Herein, we combine the lifetime tuning (SPLIT) approach with 2PE-CW-STED to overcome this limitation. The SPLIT approach is employed to discard fluorescence photons lacking super-resolution information, by means of a pixel-by-pixel phasor approach. Combining the SPLIT approach with image deconvolution further optimizes the signal-to-noise/background ratio.

  16. Carbon dioxide splitting in a dielectric barrier discharge plasma: a combined experimental and computational study.

    PubMed

    Aerts, Robby; Somers, Wesley; Bogaerts, Annemie

    2015-02-01

    Plasma technology is gaining increasing interest for the splitting of CO2 into CO and O2 . We have performed experiments to study this process in a dielectric barrier discharge (DBD) plasma with a wide range of parameters. The frequency and dielectric material did not affect the CO2 conversion and energy efficiency, but the discharge gap can have a considerable effect. The specific energy input has the most important effect on the CO2 conversion and energy efficiency. We have also presented a plasma chemistry model for CO2 splitting, which shows reasonable agreement with the experimental conversion and energy efficiency. This model is used to elucidate the critical reactions that are mostly responsible for the CO2 conversion. Finally, we have compared our results with other CO2 splitting techniques and we identified the limitations as well as the benefits and future possibilities in terms of modifications of DBD plasmas for greenhouse gas conversion in general. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Neural dynamics of 3-D surface perception: figure-ground separation and lightness perception.

    PubMed

    Kelly, F; Grossberg, S

    2000-11-01

    This article develops the FACADE theory of three-dimensional (3-D) vision to simulate data concerning how two-dimensional pictures give rise to 3-D percepts of occluded and occluding surfaces. The theory suggests how geometrical and contrastive properties of an image can either cooperate or compete when forming the boundary and surface representations that subserve conscious visual percepts. Spatially long-range cooperation and short-range competition work together to separate boundaries of occluding figures from their occluded neighbors, thereby providing sensitivity to T-junctions without the need to assume that T-junction "detectors" exist. Both boundary and surface representations of occluded objects may be amodally completed, whereas the surface representations of unoccluded objects become visible through modal processes. Computer simulations include Bregman-Kanizsa figure-ground separation, Kanizsa stratification, and various lightness percepts, including the Münker-White, Benary cross, and checkerboard percepts.

  18. Experimental methods of post-growth tuning of the excitonic fine structure splitting in semiconductor quantum dots

    PubMed Central

    2012-01-01

    Deterministic sources of polarization entangled photon pairs on demand are considered as important building blocks for quantum communication technology. It has been demonstrated that semiconductor quantum dots (QDs), which exhibit a sufficiently small excitonic fine structure splitting (FSS) can be used as triggered, on-chip sources of polarization entangled photon pairs. As-grown QDs usually do not have the required values of the FSS, making the availability of post-growth tuning techniques highly desired. This article reviews the effect of different post-growth treatments and external fields on the FSS such as thermal annealing, magnetic fields, the optical Stark effect, electric fields, and anisotropic stress. As a consequence of the tuning of the FSS, for some tuning techniques a rotation of the polarization of the emitted light is observed. The joint modification of polarization orientation and FSS can be described by an anticrossing of the bright excitonic states. PMID:22726724

  19. Investigation of upwind, multigrid, multiblock numerical schemes for three dimensional flows. Volume 1: Runge-Kutta methods for a thin layer Navier-Stokes solver

    NASA Technical Reports Server (NTRS)

    Cannizzaro, Frank E.; Ash, Robert L.

    1992-01-01

    A state-of-the-art computer code has been developed that incorporates a modified Runge-Kutta time integration scheme, upwind numerical techniques, multigrid acceleration, and multi-block capabilities (RUMM). A three-dimensional thin-layer formulation of the Navier-Stokes equations is employed. For turbulent flow cases, the Baldwin-Lomax algebraic turbulence model is used. Two different upwind techniques are available: van Leer's flux-vector splitting and Roe's flux-difference splitting. Full approximation multi-grid plus implicit residual and corrector smoothing were implemented to enhance the rate of convergence. Multi-block capabilities were developed to provide geometric flexibility. This feature allows the developed computer code to accommodate any grid topology or grid configuration with multiple topologies. The results shown in this dissertation were chosen to validate the computer code and display its geometric flexibility, which is provided by the multi-block structure.

  20. Crustal structure and deformation under the Longmenshan and its surroundings revealed by receiver function data

    NASA Astrophysics Data System (ADS)

    Sun, Ya; Liu, Jianxin; Zhou, Keping; Chen, Bo; Guo, Rongwen

    2015-07-01

    The convergence of India and Eurasia and the obstruction from the rigid Sichuan Basin cause the Longmenshan (LMS) to have the steepest topographic gradient at the eastern margin of the Tibetan Plateau. However, the mechanisms of surface uplift are still controversial. In this paper, we estimate the crustal structure and deformation under the LMS and its surroundings by analyzing a large amount of receiver function data recorded by regional seismic networks of the China Earthquake Administration. We apply a comprehensive splitting measurement technique on Ps conversion phase at the Moho (Moho Ps splitting) to calculate crustal anisotropy from azimuthal variations of receiver functions. Our results show that most of the seismic stations beneath the LMS area exhibit significant seismic anisotropy with the splitting time of 0.22-0.94 s and a fast polarization direction of NW-SE, while less or even no crustal anisotropy has been observed under the Sichuan Basin. Comparing the fast polarization directions of Moho Ps splitting with the indicators of lithospheric deformation (such as shear wave splitting, absolute plate motion, and global positioning system) imply a consistent tendency of deformation between the lower crust and upper mantle, but decoupling deformation in the crust beneath the LMS area. We further compare Moho Ps splitting time to that estimated from previous SKS splitting, indicating that crustal anisotropy is an important source of the SKS splitting time in this study area. In addition, a thick crust (>50 km) with high Vp/Vs values (1.74-1.86) is also observed using the H-κ stacking method. These seismic observations are consistent with the scenario that the LMS area has been built by the lower crustal flow. Combined with the seismic reflection/refraction profile and geology studies, we further suggest that the lower crustal flow may extrude upward into the upper crust along the steeply dipping strike faults under the LMS area, resulting in the surface uplift of the LMS.

  1. Evaluation of Fiber Reinforced Cement Using Digital Image Correlation

    PubMed Central

    Melenka, Garrett W.; Carey, Jason P.

    2015-01-01

    The effect of short fiber reinforcements on the mechanical properties of cement has been examined using a splitting tensile – digital image correlation (DIC) measurement method. Three short fiber reinforcement materials have been used in this study: fiberglass, nylon, and polypropylene. The method outlined provides a simple experimental setup that can be used to evaluate the ultimate tensile strength of brittle materials as well as measure the full field strain across the surface of the splitting tensile test cylindrical specimen. Since the DIC measurement technique is a contact free measurement this method can be used to assess sample failure. PMID:26039590

  2. Superconducting resonators as beam splitters for linear-optics quantum computation.

    PubMed

    Chirolli, Luca; Burkard, Guido; Kumar, Shwetank; Divincenzo, David P

    2010-06-11

    We propose and analyze a technique for producing a beam-splitting quantum gate between two modes of a ring-resonator superconducting cavity. The cavity has two integrated superconducting quantum interference devices (SQUIDs) that are modulated by applying an external magnetic field. The gate is accomplished by applying a radio frequency pulse to one of the SQUIDs at the difference of the two mode frequencies. Departures from perfect beam splitting only arise from corrections to the rotating wave approximation; an exact calculation gives a fidelity of >0.9992. Our construction completes the toolkit for linear-optics quantum computing in circuit quantum electrodynamics.

  3. Production and detection of atomic hexadecapole at Earth's magnetic field.

    PubMed

    Acosta, V M; Auzinsh, M; Gawlik, W; Grisins, P; Higbie, J M; Jackson Kimball, D F; Krzemien, L; Ledbetter, M P; Pustelny, S; Rochester, S M; Yashchuk, V V; Budker, D

    2008-07-21

    Optical magnetometers measure magnetic fields with extremely high precision and without cryogenics. However, at geomagnetic fields, important for applications from landmine removal to archaeology, they suffer from nonlinear Zeeman splitting, leading to systematic dependence on sensor orientation. We present experimental results on a method of eliminating this systematic error, using the hexadecapole atomic polarization moment. In particular, we demonstrate selective production of the atomic hexadecapole moment at Earth's magnetic field and verify its immunity to nonlinear Zeeman splitting. This technique promises to eliminate directional errors in all-optical atomic magnetometers, potentially improving their measurement accuracy by several orders of magnitude.

  4. Interface projection techniques for fluid-structure interaction modeling with moving-mesh methods

    NASA Astrophysics Data System (ADS)

    Tezduyar, Tayfun E.; Sathe, Sunil; Pausewang, Jason; Schwaab, Matthew; Christopher, Jason; Crabtree, Jason

    2008-12-01

    The stabilized space-time fluid-structure interaction (SSTFSI) technique developed by the Team for Advanced Flow Simulation and Modeling (T★AFSM) was applied to a number of 3D examples, including arterial fluid mechanics and parachute aerodynamics. Here we focus on the interface projection techniques that were developed as supplementary methods targeting the computational challenges associated with the geometric complexities of the fluid-structure interface. Although these supplementary techniques were developed in conjunction with the SSTFSI method and in the context of air-fabric interactions, they can also be used in conjunction with other moving-mesh methods, such as the Arbitrary Lagrangian-Eulerian (ALE) method, and in the context of other classes of FSI applications. The supplementary techniques currently consist of using split nodal values for pressure at the edges of the fabric and incompatible meshes at the air-fabric interfaces, the FSI Geometric Smoothing Technique (FSI-GST), and the Homogenized Modeling of Geometric Porosity (HMGP). Using split nodal values for pressure at the edges and incompatible meshes at the interfaces stabilizes the structural response at the edges of the membrane used in modeling the fabric. With the FSI-GST, the fluid mechanics mesh is sheltered from the consequences of the geometric complexity of the structure. With the HMGP, we bypass the intractable complexities of the geometric porosity by approximating it with an “equivalent”, locally-varying fabric porosity. As test cases demonstrating how the interface projection techniques work, we compute the air-fabric interactions of windsocks, sails and ringsail parachutes.

  5. An efficient solution technique for shockwave-boundary layer interactions with flow separation and slot suction effects

    NASA Technical Reports Server (NTRS)

    Edwards, Jack R.; Mcrae, D. Scott

    1991-01-01

    An efficient method for computing two-dimensional compressible Navier-Stokes flow fields is presented. The solution algorithm is a fully-implicit approximate factorization technique based on an unsymmetric line Gauss-Seidel splitting of the equation system Jacobian matrix. Convergence characteristics are improved by the addition of acceleration techniques based on Shamanskii's method for nonlinear equations and Broyden's quasi-Newton update. Characteristic-based differencing of the equations is provided by means of Van Leer's flux vector splitting. In this investigation, emphasis is placed on the fast and accurate computation of shock-wave-boundary layer interactions with and without slot suction effects. In the latter context, a set of numerical boundary conditions for simulating the transpiration flow in an open slot is devised. Both laminar and turbulent cases are considered, with turbulent closure provided by a modified Cebeci-Smith algebraic model. Comparisons with computational and experimental data sets are presented for a variety of interactions, and a fully-coupled simulation of a plenum chamber/inlet flowfield with shock interaction and suction is also shown and discussed.

  6. Split off-specular reflection and surface scattering from woven materials

    NASA Astrophysics Data System (ADS)

    Pont, Sylvia C.; Koenderink, Jan J.

    2003-03-01

    We measured radiance distributions for black lining cloth and copper gauze using the convenient technique of wrapping the materials around a circular cylinder, irradiating it with a parallel light source and collecting the scattered radiance by a digital camera. One family of parallel threads (weave or weft) was parallel to the cylinder generator. The most salient features for such glossy plane weaves are a splitting up of the reflection peak due to the wavy variations in local slopes of the threads around the cylinders and a surface scattering lobe due to the threads that run along the cylinder. These scattering characteristics are quite different from the (off-)specular peaks and lobes that were found before for random rough specular surfaces. The split off-specular reflection is due to the regular structures in our samples of man-made materials. We derived simple approximations for these reflectance characteristics using geometrical optics.

  7. Circularly split-ring-resonator-based frequency-reconfigurable antenna

    NASA Astrophysics Data System (ADS)

    Rahman, M. A.; Faruque, M. R. I.; Islam, M. T.

    2017-01-01

    In this paper, an antenna with frequency configurability in light of a circularly split-ring resonator (CSRR) is introduced. The proposed reconfigurable monopole antenna consists of a microstrip-fed hook-shaped structure and a CSRR having single reconfigurable split only. A new band of radiation unlike the band radiated from monopole only is observed due to magnetic coupling between the CSRR and the monopole antenna. The resonance frequency of the CSRR can be arbitrarily chosen by varying the dimension and relative position of its gap with the monopole, which leads the antenna to become reconfigurable one. By using a single switch with perfect electric conductor at the gap of CSRR cell, the effect of CSRR can be deactivated and, hence, it is possible to suppress the corresponding resonance, resulting in a frequency-reconfigurable antenna. Commercially available Computer Simulation Technology microwave studio based on finite integration technique was adopted throughout the study.

  8. Unruptured internal carotid-posterior communicating artery aneurysm splitting the oculomotor nerve: a case report and literature review.

    PubMed

    Toyota, Shingo; Taki, Takuyu; Wakayama, Akatsuki; Yoshimine, Toshiki

    2014-08-01

    Objective To report a rare case of unruptured internal carotid-posterior communicating artery (IC-PC) aneurysm splitting the oculomotor nerve treated by clipping and to review the previously published cases. Case Presentation A 42-year-old man suddenly presented with left oculomotor paresis. Three-dimensional digital subtraction angiography (3D DSA) demonstrated a left IC-PC aneurysm with a bulging part. During surgery, it was confirmed that the bulging part split the oculomotor nerve. After the fenestrated oculomotor nerve was dissected from the bulging part with a careful microsurgical technique, neck clipping was performed. After the operation, the symptoms of oculomotor nerve paresis disappeared within 2 weeks. Conclusions We must keep in mind the possibility of an anomaly of the oculomotor nerve, including fenestration, and careful observation and manipulation should be performed to preserve the nerve function during surgery, even though it is very rare.

  9. Unruptured Internal Carotid-Posterior Communicating Artery Aneurysm Splitting the Oculomotor Nerve: A Case Report and Literature Review

    PubMed Central

    Toyota, Shingo; Taki, Takuyu; Wakayama, Akatsuki; Yoshimine, Toshiki

    2014-01-01

    Objective To report a rare case of unruptured internal carotid-posterior communicating artery (IC-PC) aneurysm splitting the oculomotor nerve treated by clipping and to review the previously published cases. Case Presentation A 42-year-old man suddenly presented with left oculomotor paresis. Three-dimensional digital subtraction angiography (3D DSA) demonstrated a left IC-PC aneurysm with a bulging part. During surgery, it was confirmed that the bulging part split the oculomotor nerve. After the fenestrated oculomotor nerve was dissected from the bulging part with a careful microsurgical technique, neck clipping was performed. After the operation, the symptoms of oculomotor nerve paresis disappeared within 2 weeks. Conclusions We must keep in mind the possibility of an anomaly of the oculomotor nerve, including fenestration, and careful observation and manipulation should be performed to preserve the nerve function during surgery, even though it is very rare. PMID:25083381

  10. Energy distribution analysis in boosted HCCI-like / LTGC engines – Understanding the trade-offs to maximize the thermal efficiency

    DOE PAGES

    Dernotte, Jeremie; Dec, John E.; Ji, Chunsheng

    2015-04-14

    A detailed understanding of the various factors affecting the trends in gross-indicated thermal efficiency with changes in key operating parameters has been carried out, applied to a one-liter displacement single-cylinder boosted Low-Temperature Gasoline Combustion (LTGC) engine. This work systematically investigates how the supplied fuel energy splits into the following four energy pathways: gross-indicated thermal efficiency, combustion inefficiency, heat transfer and exhaust losses, and how this split changes with operating conditions. Additional analysis is performed to determine the influence of variations in the ratio of specific heat capacities (γ) and the effective expansion ratio, related to the combustion-phasing retard (CA50), onmore » the energy split. Heat transfer and exhaust losses are computed using multiple standard cycle analysis techniques. Furthermore, the various methods are evaluated in order to validate the trends.« less

  11. Splitting parameter yield (SPY): A program for semiautomatic analysis of shear-wave splitting

    NASA Astrophysics Data System (ADS)

    Zaccarelli, Lucia; Bianco, Francesca; Zaccarelli, Riccardo

    2012-03-01

    SPY is a Matlab algorithm that analyzes seismic waveforms in a semiautomatic way, providing estimates of the two observables of the anisotropy: the shear-wave splitting parameters. We chose to exploit those computational processes that require less intervention by the user, gaining objectivity and reliability as a result. The algorithm joins the covariance matrix and the cross-correlation techniques, and all the computation steps are interspersed by several automatic checks intended to verify the reliability of the yields. The resulting semiautomation generates two new advantages in the field of anisotropy studies: handling a huge amount of data at the same time, and comparing different yields. From this perspective, SPY has been developed in the Matlab environment, which is widespread, versatile, and user-friendly. Our intention is to provide the scientific community with a new monitoring tool for tracking the temporal variations of the crustal stress field.

  12. Symmetry-Based Variance Reduction Applied to 60Co Teletherapy Unit Monte Carlo Simulations

    NASA Astrophysics Data System (ADS)

    Sheikh-Bagheri, D.

    A new variance reduction technique (VRT) is implemented in the BEAM code [1] to specifically improve the efficiency of calculating penumbral distributions of in-air fluence profiles calculated for isotopic sources. The simulations focus on 60Co teletherapy units. The VRT includes splitting of photons exiting the source capsule of a 60Co teletherapy source according to a splitting recipe and distributing the split photons randomly on the periphery of a circle, preserving the direction cosine along the beam axis, in addition to the energy of the photon. It is shown that the use of the VRT developed in this work can lead to a 6-9 fold improvement in the efficiency of the penumbral photon fluence of a 60Co beam compared to that calculated using the standard optimized BEAM code [1] (i.e., one with the proper selection of electron transport parameters).

  13. System, Apparatus and Method Employing a Dual Head Laser

    NASA Technical Reports Server (NTRS)

    Coyle, Donald B. (Inventor); Stysley, Paul R. (Inventor); Poulios, Demetrios (Inventor)

    2015-01-01

    A system, apparatus and method employing a laser with a split-head, V-assembly gain material configuration. Additionally, the present invention is directed to techniques to better dissipate or remove unwanted energies in laser operations. The present invention is also directed to techniques for better collimated laser beams, with single spatial mode quality (TEM00), with improved efficiency, in extreme environments, such as in outer space.

  14. Rapid and improved gas-liquid chromatography technique for detection of hippurate hydrolysis by Campylobacter jejuni and Campylobacter coli.

    PubMed Central

    Bär, W; Fricke, G

    1987-01-01

    A gas-liquid chromatographic method which requires no chloroform extraction of the split products has been investigated for the detection of hippurate hydrolysis by Campylobacter spp. This technique gave better reproducibility than other tests also used in this study and allows the routine use of the gas-liquid chromatographic method for identification of Campylobacter isolates. PMID:3654950

  15. Refractive index sensor based on optical fiber end face using pulse reference-based compensation technique

    NASA Astrophysics Data System (ADS)

    Bian, Qiang; Song, Zhangqi; Zhang, Xueliang; Yu, Yang; Chen, Yuzhong

    2018-03-01

    We proposed a refractive index sensor based on optical fiber end face using pulse reference-based compensation technique. With good compensation effect of this compensation technique, the power fluctuation of light source, the change of optic components transmission loss and coupler splitting ratio can be compensated, which largely reduces the background noise. The refractive index resolutions can achieve 3.8 × 10-6 RIU and1.6 × 10-6 RIU in different refractive index regions.

  16. A color video display technique for flow field surveys

    NASA Technical Reports Server (NTRS)

    Winkelmann, A. E.; Tsao, C. P.

    1982-01-01

    A computer driven color video display technique has been developed for the presentation of wind tunnel flow field survey data. The results of both qualitative and quantitative flow field surveys can be presented in high spatial resolutions color coded displays. The technique has been used for data obtained with a hot-wire probe, a split-film probe, a Conrad (pitch) probe and a 5-tube pressure probe in surveys above and behind a wing with partially stalled and fully stalled flow.

  17. Synthesis of Chemiluminescent Esters: A Combinatorial Synthesis Experiment for Organic Chemistry Students

    ERIC Educational Resources Information Center

    Duarte, Robert; Nielson, Janne T.; Dragojlovic, Veljko

    2004-01-01

    A group of techniques aimed at synthesizing a large number of structurally diverse compounds is called combinatorial synthesis. Synthesis of chemiluminescence esters using parallel combinatorial synthesis and mix-and-split combinatorial synthesis is experimented.

  18. Protein trans-splicing on an M13 bacteriophage: towards directed evolution of a semisynthetic split intein by phage display.

    PubMed

    Garbe, Daniel; Thiel, Ilka V; Mootz, Henning D

    2010-10-01

    Split inteins link their fused peptide or protein sequences with a peptide bond in an autocatalytic reaction called protein trans-splicing. This reaction is becoming increasingly important for a variety of applications in protein semisynthesis, polypeptide circularisation, construction of biosensors, or segmental isotopic labelling of proteins. However, split inteins exhibit greatly varying solubility, efficiency and tolerance towards the nature of the fused sequences as well as reaction conditions. We envisioned that phage display as an in vitro selection technique would provide a powerful tool for the directed evolution of split inteins with improved properties. As a first step towards this goal, we show that presentation of active split inteins on an M13 bacteriophage is feasible. Two different C-terminal intein fragments of the Ssp DnaB intein, artificially split at amino acid positions 104 and 11, were encoded in a phagemid vector in fusion to a truncated gpIII protein. For efficient production of hybrid phages, the presence of a soluble domain tag at their N-termini was necessary. Immunoblot analysis revealed that the hybrid phages supported protein trans-splicing with a protein or a synthetic peptide, respectively, containing the complementary intein fragment. Incorporation of biotin or desthiobiotin by this reaction provides a straightforward strategy for future enrichment of desired mutants from randomised libraries of the C-terminal intein fragments on streptavidin beads. Protein semisynthesis on a phage could also be exploited for the selection of chemically modified proteins with unique properties. © 2010 European Peptide Society and John Wiley & Sons, Ltd.

  19. Mode-splitting for refractive index sensing in fluorescent whispering gallery mode resonators with broken symmetry

    NASA Astrophysics Data System (ADS)

    Kang, Yvonne Q.; François, Alexandre; Riesen, Nicolas; Monro, Tanya M.

    2018-02-01

    Whispering Gallery Mode (WGM) biosensors have been widely exploited over the past decade, owing to their unprecedented detection limits and label free capability. WGM based sensing mechanisms, such as resonance frequency shift, linewidth broadening, and splitting of the two counter-propagating WGMs, have been extensively researched and applied for bio-chemical sensing. However, the mode-splitting of the originally degenerate WGMs from different equatorial planes on a fluorescent microsphere has not been fully investigated. In this work, we break the symmetry of the surrounding environment outside the microsphere by partially embedding the sphere into a high-refractive-index medium (i.e. glue), to lift the degeneracy of the modes from different WGM planes. The split-modes from multiple planes of the fluorescent microsphere are indiscriminately collected. It is found that the effective quality factor Q of the WGMs increases non-conventionally as the Refractive Index (RI) of the probing liquid increases up to the point where it is equal to that of the glue. This presents a new methodology for quantifying changes in the probing environment based on the Q spoiling of the resonances as determined by the RI difference between the environment and that of the reference glue. Furthermore, we find that this sensing platform opens the door to simple self-referenced sensing techniques based on the analysis of the spectral positions of subsets of the split modes.

  20. Occurrence of a 'bad' split and success of initial mandibular healing: a review of 524 sagittal ramus osteotomies in 262 patients.

    PubMed

    Posnick, J C; Choi, E; Liu, S

    2016-10-01

    The purpose of this study was to assess the prevalence of a 'bad' split after sagittal ramus osteotomies (SRO) and report the results of initial mandibular healing. A retrospective cohort study derived from patients treated by a single surgeon at one institution between 2004 and 2013 was performed. An index group consisting of a series of subjects with a spectrum of bimaxillary dentofacial deformities also involving the chin and symptomatic chronic obstructive nasal breathing was identified. The SRO design, bicortical screw fixation technique, and perioperative management were consistent. Outcome variables included the occurrence of a 'bad' split and the success of initial SRO healing. Two hundred sixty-two subjects undergoing 524 SROs met the inclusion criteria. Their average age was 25 years (range 13-63 years) and 134 were female (51%). Simultaneous removal of a third molar was performed during 209 of the SROs (40%). There were no 'bad' splits. All subjects achieved successful bone union, the planned occlusion, and return to a chewing diet and physical activities by 5 weeks after surgery. The presence of a third molar removed during SRO was not associated with an increased frequency of a 'bad' split or delayed mandibular healing. Copyright © 2016 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  1. Percutaneous Mitral Valve Dilatation: Single Balloon versus Double Balloon - A Finite Element Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schievano, Silvia; Kunzelman, Karyn; Nicosia, Mark

    2009-01-01

    Background: Percutaneous mitral valve (MV) dilatation is performed with either a single balloon (SB) or double balloon (DB) technique. The aim of this study was to compare the two balloon system results using the finite element (FE) method. Methods and Results: An established FE model of the MV was modified by fusing the MV leaflet edges at commissure level to simulate a stenotic valve (orifice area=180mm2). A FE model of a 30mm SB (low-pressure, elastomeric balloon) and an 18mm DB system (high-pressure, non-elastic balloon) was created. Both SB and DB simulations resulted in splitting of the commissures and subsequent stenosismore » dilatation (final MV area=610mm2 and 560mm2 respectively). Stresses induced by the two balloon systems varied across the valve. At the end of inflation, SB showed higher stresses in the central part of the leaflets and at the commissures compared to DB simulation, which demonstrated a more uniform stress distribution. The higher stresses in the SB analysis were due to the mismatch of the round balloon shape with the oval mitral orifice. The commissural split was not easily accomplished with the SB due to its high compliance. The high pressure applied to the DB guaranteed the commissural split even when high forces were required to break the commissure welds. Conclusions: The FE model demonstrated that MV dilatation can be accomplished by both SB and DB techniques. However, the DB method resulted in higher probability of splitting of the fused commissures and less damage caused to the MV leaflets by overstretching.« less

  2. In Situ Splitting of a Rib Bone Graft for Reconstruction of Orbital Floor and Medial Wall.

    PubMed

    Uemura, Tetsuji; Yanai, Tetsu; Yasuta, Masato; Harada, Yoshimi; Morikawa, Aya; Watanabe, Hidetaka; Kurokawa, Masato

    2017-06-01

    In situ splitting of rib bone graft was conducted in 22 patients for the repair of orbital fracture with no other complicating fractures. A bone graft was harvested from the sixth or seventh rib in the right side. The repair of the orbital floor and medial wall was successful in all the cases. Ten patients had bone grafting to the orbital floor, eight had it done onto medial wall, and 4 onto both floor and wall after reduction. The mean length of in situ rib bone graft was 40.9 mm (range, 20-70 mm), the mean width of these was 14.9 mm (range, 8-20 mm). The bone grafting was done by one leaf for 15 cases and two leafs for 7 cases in size of defects. The technique of in situ splitting of a rib bone graft for the repair of the orbital floor and medial wall is a simple and safe procedure, easily taking out the in situ splitting of a rib, and less pain in donor site. It has proved to be an optimal choice in craniofacial reconstruction, especially the defects of orbital floor and medial wall.

  3. Compensation of the Ionospheric Effects on SAR Interferogram Based on Range Split-Spectrum and Azimuth Offset Methods - a Case Study of Yushu Earthquake

    NASA Astrophysics Data System (ADS)

    He, Y. F.; Zhu, W.; Zhang, Q.; Zhang, W. T.

    2018-04-01

    InSAR technique can measure the surface deformation with the accuracy of centimeter-level or even millimeter and therefore has been widely used in the deformation monitoring associated with earthquakes, volcanoes, and other geologic process. However, ionospheric irregularities can lead to the wavy fringes in the low frequency SAR interferograms, which disturb the actual information of geophysical processes and thus put severe limitations on ground deformations measurements. In this paper, an application of two common methods, the range split-spectrum and azimuth offset methods are exploited to estimate the contributions of the ionosphere, with the aim to correct ionospheric effects in interferograms. Based on the theoretical analysis and experiment, a performance analysis is conducted to evaluate the efficiency of these two methods. The result indicates that both methods can mitigate the ionospheric effect in SAR interferograms and the range split-spectrum method is more precise than the other one. However, it is also found that the range split-spectrum is easily contaminated by the noise, and the achievable accuracy of the azimuth offset method is limited by the ambiguous integral constant, especially with the strong azimuth variations induced by the ionosphere disturbance.

  4. Phaco chop technique for cataract surgery in the dog.

    PubMed

    Warren, Christi

    2004-01-01

    Phaco chop is a bimanual phacoemulsification technique to remove cataracts. The technique was first presented at the 1993 3rd American-International Congress on Cataract, IOL, and Refractive Surgery in Seattle by Dr Kunihiro Nagahara. He compared the lens with a block of wood and by applying chopping forces parallel to the natural planes of the lens lamellae, as one does in splitting wood, a nucleus can be cleaved with surprisingly little force and time. Dr Nagahara used the phaco tip to impale and high vacuum to hold the nucleus while a second instrument, or chopper, hooked the equator and was pulled centrally, splitting the nucleus along its natural cleavage planes. This was a breakthrough for surgeons who had been utilizing several minutes of phaco energy sculpting grooves and bowls in a lens. Studies have shown that compared with four-quadrant 'divide and conquer', the phaco chop technique uses less phaco time and energy, significantly reducing endothelial cell damage. Other advantages of phaco chop include reduction of zonular and capsular stress because forces are directed toward an opposing instrument and the phaco tip is kept in a central 'safe zone' in the middle of the pupil. This technique has also been successfully adapted to the canine phacoemulsification procedure. The larger canine lens requires some modifications, and lenses with hard nuclear and cortical material may not be amenable to this procedure.

  5. Piezosurgery for the lingual split technique in mandibular third molar removal: a suggestion.

    PubMed

    Pippi, Roberto; Alvaro, Roberto

    2013-03-01

    The lingual split technique is a surgical procedure for extraction of impacted mandibular third molar throughout a lingual approach. The main disadvantage of this technique is the high rate of temporary lingual nerve injury mainly because of the trauma induced by the lingual flap retraction. The purpose of this paper is to suggest the use of piezosurgery in performing the lingual cortical plate osteotomy of the third molar alveolar process. Surgical procedure was performed under general anesthesia, and it lasted approximately 60 minutes. After the buccal and lingual full-thickness flaps were incised and elevated, a piezosurgical device was used for osteotomy. A well-defined bony window was then removed, and it allowed the entire tooth was extracted in a lingual direction. The patient did not show any neurological postoperative complication. Lingual and inferior alveolar nerve functionality was normal before as well as after surgery. The use of piezoelectric surgery seems to be a good option in removing lower third molars when a lingual access is clearly indicated. The only disadvantage of this technique can be represented by an operating time lengthening possibly because of a lower power cut of the piezoelectric device, to the high mineralization of the mandibular cortical bone and to the use of inserts with a low degree of sharpening.

  6. SU-G-TeP2-11: Initial Evaluation of a Novel Split-Filter Dual-Energy CT for Use in Radiation Oncology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, J; Huang, J; Szczykutowicz, T

    2016-06-15

    Purpose: To perform an initial evaluation of a novel split-filter dual-energy CT (DECT) system with the goal of understanding the clinical utility and limitations of the system for radiation therapy. Methods: Several phantoms were imaged using the split-filter DECT technique on the Siemens Edge CT scanner using a range of clinically-relevant doses. The optimum-contrast reconstruction, the mixed reconstruction, and the monoenergetic reconstructions (ranging from 40 keV to 190 keV) were evaluated. Each image was analyzed for CT number accuracy, uniformity, noise, low-contrast visibility (LCV), spatial resolution and geometric distortion. For comparison purposes, all parameters were evaluated on 120 kVp single-energymore » CT (SECT) scans used for treatment planning, as well as, a sequential-scan DECT technique for corresponding doses. Results: For all DECT reconstructions no observable geometric distortion was found. Both the optimal-contrast and mixed images demonstrated slight improvements in LCV and noise when compared to the SECT, and slight reductions in CT number accuracy and spatial resolution. The CT numbers trended as expected for the monoenergetic reconstructions, with CT number accuracy within 50 HU for materials of density <2 g/cm3. Spatial resolution increased with energy, and for monoenergetic reconstructions >70 keV the spatial resolution exceeded that of the SECT. The noise in the monoenergetic reconstructions increased with decreasing energy. Thus, the image uniformity, signal-to-noise ratio and LCV were diminished at lower energies (70 keV). Applying iterative reconstruction techniques to the low-energy images reduced noise and improved LCV. The signal-to-noise ratio was stable for energies >100 keV. Conclusion: The initial commissioning of the novel split-filter DECT technology demonstrated favorable results for clinical implementation. The mixed reconstruction showed potential as a replacement for the treatment planning SECT. The image parameters for the monoenergetic reconstructions varied appropriately with energy. This work provides an initial understanding of the limitations and potential applications for monoenergetic imaging.« less

  7. Estimation of splitting functions from Earth's normal mode spectra using the neighbourhood algorithm

    NASA Astrophysics Data System (ADS)

    Pachhai, Surya; Tkalčić, Hrvoje; Masters, Guy

    2016-01-01

    The inverse problem for Earth structure from normal mode data is strongly non-linear and can be inherently non-unique. Traditionally, the inversion is linearized by taking partial derivatives of the complex spectra with respect to the model parameters (i.e. structure coefficients), and solved in an iterative fashion. This method requires that the earthquake source model is known. However, the release of energy in large earthquakes used for the analysis of Earth's normal modes is not simple. A point source approximation is often inadequate, and a more complete account of energy release at the source is required. In addition, many earthquakes are required for the solution to be insensitive to the initial constraints and regularization. In contrast to an iterative approach, the autoregressive linear inversion technique conveniently avoids the need for earthquake source parameters, but it also requires a number of events to achieve full convergence when a single event does not excite all singlets well. To build on previous improvements, we develop a technique to estimate structure coefficients (and consequently, the splitting functions) using a derivative-free parameter search, known as neighbourhood algorithm (NA). We implement an efficient forward method derived using the autoregresssion of receiver strips, and this allows us to search over a multiplicity of structure coefficients in a relatively short time. After demonstrating feasibility of the use of NA in synthetic cases, we apply it to observations of the inner core sensitive mode 13S2. The splitting function of this mode is dominated by spherical harmonic degree 2 axisymmetric structure and is consistent with the results obtained from the autoregressive linear inversion. The sensitivity analysis of multiple events confirms the importance of the Bolivia, 1994 earthquake. When this event is used in the analysis, as little as two events are sufficient to constrain the splitting functions of 13S2 mode. Apart from not requiring the knowledge of earthquake source, the newly developed technique provides an approximate uncertainty measure of the structure coefficients and allows us to control the type of structure solved for, for example to establish if elastic structure is sufficient.

  8. [Necrotizing fasciitis of the hand and forearm : Acute surgical treatment and defect reconstruction with MatriDerm® and split-thickness skin graft].

    PubMed

    Niedermueller, B; Singer, G; Pickl, P; Jesacher, M

    2018-03-01

    This case report describes a 55-year-old male patient with type II necrotizing fasciitis (NF) of the hand and forearm. The rapid progression of the tissue infection could be successfully stopped with radical surgical débridement and antibiotic therapy. For the reconstruction of the extensive loss of soft tissue a combination of split-thickness skin graft (STSG) and the synthetic dermal substitute MatriDerm® was used. In cases of NF, MatriDerm® and STSG provide a rapidly available and simple alternative to other reconstruction techniques.

  9. Eddy current heating in magnetic refrigerators

    NASA Technical Reports Server (NTRS)

    Kittel, Peter

    1990-01-01

    Eddy current heating can be a significant source of parasitic heating in low temperature magnetic refrigerators. To study this problem a technique to approximate the heating due to eddy currents has been developed. A formula is presented for estimating the heating within a variety of shapes commonly found in magnetic refrigerators. These shapes include circular, square, and rectangular rods; cylindrical and split cylindrical shells; wire loops; and 'coil foil. One set of components evaluated are different types of thermal radiation shields. This comparison shows that a simple split shield is almost as effective (only 23 percent more heating) as using a shield, with the same axial thermal conductivity, made of 'coil foil'.

  10. On the possibility of detecting weak magnetic fields in variable white dwarfs

    NASA Technical Reports Server (NTRS)

    Jones, Philip W.; Hansen, Carl J.; Pesnell, W. Dean; Kawaler, Steven D.

    1989-01-01

    It is suggested that 'weak' magnetic fields of strengths less than 10 to the 6th G may be detectable in some variable white dwarfs. Weak fields can cause subtle changes in the Fourier power spectra of these stars in the form of 'splitting' in frequency of otherwise degenerate signals. Present-day observational and analysis techniques are capable of detecting these changes. It is suggested suggested, by listing some well-studied candidate stars, that perhaps the magnetic signature of splitting has already been observed in at least one object and that the difficult task of intensive measurements of weak fields should now be undertaken of those candidates.

  11. Antimicrobial-impregnated dressing combined with negative-pressure wound therapy increases split-thickness skin graft engraftment: a simple effective technique.

    PubMed

    Wu, Cheng-Chun; Chew, Khong-Yik; Chen, Chien-Chang; Kuo, Yur-Ren

    2015-01-01

    Immobilization and adequate surface contact to wounds are critical for skin graft take. Techniques such as the tie-over dressing, cotton bolster, and vacuum-assisted closure are used to address this, but each has its limitations. This study is designed to assess the effect of antimicrobial-impregnated dressing (AMD) combined with negative-pressure wound therapy (NPWT) on skin graft survival. Retrospective case-control study : Patients with chronic or contaminated wounds treated with split-thickness skin graft. A broad spectrum of wounds was included, from causes such as trauma, burns, chronic diabetic ulcers, and infection. Antimicrobial-impregnated dressing, which contains 0.2% polyhexamethylene biguanide, with NPWT MAIN OUTCOME MEASURE:: Success of skin graft : In the AMD group, all skin grafts achieved 100% take without secondary intervention. No infection or graft failure was observed in any patients, and no complications, such as hematoma or seroma formation, were noted, although in the control group partial loss of skin grafts was noted in 3 patients. Infection and inadequate immobilization were thought to be the main reasons. There were no hematoma or seroma formations in the control group. Use of an AMD dressing with NPWT after split-thickness skin grafting can be an effective method to ensure good graft to wound contact and enhances skin graft take in chronic and contaminated wounds.

  12. Sunlight-Driven Hydrogen Formation by Membrane-Supported Photoelectrochemical Water Splitting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lewis, Nathan S.

    2014-03-26

    This report describes the significant advances in the development of the polymer-supported photoelectrochemical water-splitting system that was proposed under DOE grant number DE-FG02-05ER15754. We developed Si microwire-array photoelectrodes, demonstrated control over the material and light-absorption properties of the microwire-array photoelectrodes, developed inexpensive processes for synthesizing the arrays, and doped the arrays p-type for use as photocathodes. We also developed techniques for depositing metal-nanoparticle catalysts of the hydrogen-evolution reaction (HER) on the wire arrays, investigated the stability and catalytic performance of the nanoparticles, and demonstrated that Ni-Mo alloys are promising earth-abundant catalysts of the HER. We also developed methods that allowmore » reuse of the single-crystalline Si substrates used for microwire growth and methods of embedding the microwire photocathodes in plastic to enable large-scale processing and deployment of the technology. Furthermore we developed techniques for controlling the structure of WO3 films, and demonstrated that structural control can improve the quantum yield of photoanodes. Thus, by the conclusion of this project, we demonstrated significant advances in the development of all components of a sunlight-driven membrane-supported photoelectrochemical water-splitting system. This final report provides descriptions of some of the scientific accomplishments that were achieved under the support of this project and also provides references to the peer-reviewed publications that resulted from this effort.« less

  13. Hospital survey on patient safety culture: psychometric analysis on a Scottish sample.

    PubMed

    Sarac, Cakil; Flin, Rhona; Mearns, Kathryn; Jackson, Jeanette

    2011-10-01

    To investigate the psychometric properties of the Hospital Survey on Patient Safety Culture on a Scottish NHS data set. The data were collected from 1969 clinical staff (estimated 22% response rate) from one acute hospital from each of seven Scottish Health boards. Using a split-half validation technique, the data were randomly split; an exploratory factor analysis was conducted on the calibration data set, and confirmatory factor analyses were conducted on the validation data set to investigate and check the original US model fit in a Scottish sample. Following the split-half validation technique, exploratory factor analysis results showed a 10-factor optimal measurement model. The confirmatory factor analyses were then performed to compare the model fit of two competing models (10-factor alternative model vs 12-factor original model). An S-B scaled χ(2) square difference test demonstrated that the original 12-factor model performed significantly better in a Scottish sample. Furthermore, reliability analyses of each component yielded satisfactory results. The mean scores on the climate dimensions in the Scottish sample were comparable with those found in other European countries. This study provided evidence that the original 12-factor structure of the Hospital Survey on Patient Safety Culture scale has been replicated in this Scottish sample. Therefore, no modifications are required to the original 12-factor model, which is suggested for use, since it would allow researchers the possibility of cross-national comparisons.

  14. High Density Metamaterials for Visible Light

    DTIC Science & Technology

    2016-11-28

    gold first and then extend the techniques to other metals for better characteristics. Bio -chemical sensors will be developed based on different split...metamaterials for Bio -chemical sensing. Using our sonicated cold development electron beam lithography process that has recently been shown to overcome

  15. SU-E-T-433: Field-In-Field Irradiation for Breast Cancer with VERO-4DRT System: A Feasibility Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hayashi, N; Mizuno, T; Takada, Y

    2015-06-15

    Purpose: The Vero-4DRT system is a dedicated system for high precision radiation therapy. However, the field size is limited at 15 cm x 15 cm and shapes by using multi-leaf collimator (MLC) without X-Jaw and Y-Jaw. Therefore VERO-4DRT system is not available to simple wedged irradiation for breast cancer. In this study, we suppose FIF with ring and/or tilt/pan angles whole breast irradiation (FIFWBI). The purpose of this study is to verify the feasibility of FIFWBI with VERO-4DRT system. Methods: As fundamental evaluation, we performed commissioning test with phantom. The absorbed dose evaluation at several reference points and dose distributionmore » including split area were performed. We planned 10 demonstrative shapes in phantom for measuring these contents with i-plan workstation (BrainLAB). As clinical evaluation, the dose distribution and dose indexes were evaluated with actual patient data. Five patients with breast cancer were designed FIFWBI radiotherapy plan with split fields. Then, the dose distribution and dose indexes (including Dmax, Dmin, D95, D5 and Homogeneity index) were evaluated in these plans. Results: As the results of fundamental evaluation, all absorbed dose errors between calculated and measured doses were within 2%. The gamma passing rates with 2 mm/3% criteria in all cases were 96±2%. As the results of clinical evaluation, the values of Dmax, D95, D50, D5, and Homogeneity Index were 41.7±0.90 Gy, 49.4±0.34 Gy, 52.26±0.24 Gy, and 1.39±0.03, respectively. For Japanese breast cancer patients, this technique was feasible. However, the large split region was happened in FIFWBI in case of patient with large breast. Conclusion: We evaluated the FIFWBI technique with VERO-4DRT system. This technique is feasible for Japanese patients, but the patient with large breast should be disagreed with this technique.« less

  16. Tunneling dynamics of double proton transfer in formic acid and benzoic acid dimers

    NASA Astrophysics Data System (ADS)

    Smedarchina, Zorka; Fernández-Ramos, Antonio; Siebrand, Willem

    2005-04-01

    Direct dynamics calculations based on instanton techniques are reported of tunneling splittings due to double proton transfer in formic and benzoic acid dimers. The results are used to assign the observed splittings to levels for which the authors of the high-resolution spectra could not provide a definitive assignment. In both cases the splitting is shown to be due mainly to the zero-point level rather than to the vibrationally or electronically excited level whose spectrum was investigated. This leads to zero-point splittings of 375MHz for (DCOOH)2 and 1107MHz for the benzoic acid dimer. Thus, contrary to earlier calculations, it is found that the splitting is considerably larger in the benzoic than in the formic acid dimer. The calculations are extended to solid benzoic acid where the asymmetry of the proton-transfer potential induced by the crystal can be overcome by suitable doping. This has allowed direct measurement of the interactions responsible for double proton transfer, which were found to be much larger than those in the isolated dimer. To account for this observation both static and dynamic effects of the crystal forces on the intradimer hydrogen bonds are included in the calculations. The same methodology, extended to higher temperatures, is used to calculate rate constants for HH, HD, and DD transfers in neat benzoic acid crystals. The results are in good agreement with reported experimental rate constants measured by NMR relaxometry and, if allowance is made for small structural changes induced by doping, with the transfer matrix elements observed in doped crystals. Hence the method used allows a unified description of tunneling splittings in the gas phase and in doped crystals as well as of transfer rates in neat crystals.

  17. Lowermost mantle anisotropy near the eastern edge of the Pacific LLSVP: constraints from SKS-SKKS splitting intensity measurements

    NASA Astrophysics Data System (ADS)

    Deng, Jie; Long, Maureen D.; Creasy, Neala; Wagner, Lara; Beck, Susan; Zandt, George; Tavera, Hernando; Minaya, Estela

    2017-08-01

    Seismic anisotropy has been documented in many portions of the lowermost mantle, with particularly strong anisotropy thought to be present along the edges of large low shear velocity provinces (LLSVPs). The region surrounding the Pacific LLSVP, however, has not yet been studied extensively in terms of its anisotropic structure. In this study, we use seismic data from southern Peru, northern Bolivia and Easter Island to probe lowermost mantle anisotropy beneath the eastern Pacific Ocean, mostly relying on data from the Peru Lithosphere and Slab Experiment and Central Andean Uplift and Geodynamics of High Topography experiments. Differential shear wave splitting measurements from phases that have similar ray paths in the upper mantle but different ray paths in the lowermost mantle, such as SKS and SKKS, are used to constrain anisotropy in D″. We measured splitting for 215 same station-event SKS-SKKS pairs that sample the eastern Pacific LLSVP at the base of the mantle. We used measurements of splitting intensity(SI), a measure of the amount of energy on the transverse component, to objectively and quantitatively analyse any discrepancies between SKS and SKKS phases. While the overall splitting signal is dominated by the upper-mantle anisotropy, a minority of SKS-SKKS pairs (∼10 per cent) exhibit strongly discrepant splitting between the phases (i.e. the waveforms require a difference in SI of at least 0.4), indicating a likely contribution from lowermost mantle anisotropy. In order to enhance lower mantle signals, we also stacked waveforms within individual subregions and applied a waveform differencing technique to isolate the signal from the lowermost mantle. Our stacking procedure yields evidence for substantial splitting due to lowermost mantle anisotropy only for a specific region that likely straddles the edge of Pacific LLSVP. Our observations are consistent with the localization of deformation and anisotropy near the eastern boundary of the Pacific LLSVP, similar to previous observations for the African LLSVP.

  18. Time-frequency characterisation of paediatric heart sounds

    NASA Astrophysics Data System (ADS)

    Leung, Terence Sze-Tat

    1998-08-01

    The operation of the heart can be monitored by the sounds it emits. Structural defects or malfunction of the heart valves will cause additional abnormal sounds such as murmurs and ejection clicks. This thesis aims to characterise the heart sounds of three groups of children who either have an Atrial Septal Defect (ASD), a Ventricular Septal Defect (VSD), or are normal. Two aspects of heart sounds have been specifically investigated; the time-frequency analysis of systolic murmurs and the identification of splitting patterns in the second heart sound. The analysis is based on 42 paediatric heart sound recordings. Murmurs are sounds generated by turbulent flow of blood in the heart. They can be found in patients with both pathological and non-pathological conditions. The acoustic quality of the murmurs generated in each heart condition are different. The first aspect of this work is to characterise the three types of murmurs in the time- frequency domain. Modern time-frequency methods including, the Wigner-Ville Distribution, Smoothed Pseudo Wigner-Ville Distribution, Choi-Williams Distribution and spectrogram have been applied to characterise the murmurs. It was found that the three classes of murmurs exhibited different signatures in their time-frequency representations. By performing Discriminant Analysis, it was shown that spectral features extracted from the time- frequency representations can be used to distinguish between the three classes. The second aspect of the research is to identify splitting patterns in the second heart sound, which consists of two acoustic components due to the closure of the aortic valve and pulmonary valve. The aortic valve usually closes before the pulmonary valve, introducing a time delay known as 'split'. The split normally varies in duration over the respiratory cycle. In certain pathologies such as the ASD, the split becomes fixed over the respiration cycle. A technique based on adaptive signal decomposition is developed to measure the split and hence to identify the splitting pattern as either 'variable' or 'fixed'. This work has successfully characterised the murmurs and splitting patterns in the three groups of patients. Features extracted can be used for diagnostic purposes.

  19. Incentive and Architecture of Multi-Band Enabled Small Cell and UE for Up-/Down-Link and Control-/User-Plane Splitting for 5G Mobile Networks

    NASA Astrophysics Data System (ADS)

    Saha, Rony Kumer; Aswakul, Chaodit

    2017-01-01

    In this paper, a multi-band enabled femtocell base station (FCBS) and user equipment (UE) architecture is proposed in a multi-tier network that consists of small cells, including femtocells and picocells deployed over the coverage of a macrocell for splitting uplink and downlink (UL/DL) as well as control-plane and user-plane (C-/U-plane) for 5G mobile networks. Since splitting is performed at the same FCBS, we define this architecture as the same base station based split architecture (SBSA). For multiple bands, we consider co-channel (CC) microwave and different frequency (DF) 60 GHz millimeter wave (mmWave) bands for FCBSs and UEs with respect to the microwave band used by their over-laid macrocell base station. All femtocells are assumed to be deployed in a 3-dimensional multi-storage building. For CC microwave band, cross-tier CC interference of femtocells with macrocell is avoided using almost blank subframe based enhanced inter-cell interference coordination techniques. The co-existence of CC microwave and DF mmWave bands for SBSA on the same FCBS and UE is first studied to show their performance disparities in terms of system capacity and spectral efficiency in order to provide incentives for employing multiple bands at the same FCBS and UE and identify a suitable band for routing decoupled UL/DL or C-/U-plane traffic. We then present a number of disruptive architectural design alternatives of multi-band enabled SBSA for 5G mobile networks for UL/DL and C-/U-plane splitting, including a disruptive and complete splitting of UL/DL and C-/U-plane as well as a combined UL/DL and C-/U-plane splitting, by exploiting dual connectivity on CC microwave and DF mmWave bands. The outperformances of SBSA in terms of system level capacity, average spectral efficiency, energy efficiency, and control-plane overhead traffic capacity in comparison with different base stations based split architecture (DBSA) are shown. Finally, a number of technical and business perspectives as well as key research issues of SBSA are discussed.

  20. Study of radar pulse compression for high resolution satellite altimetry

    NASA Technical Reports Server (NTRS)

    Dooley, R. P.; Nathanson, F. E.; Brooks, L. W.

    1974-01-01

    Pulse compression techniques are studied which are applicable to a satellite altimeter having a topographic resolution of + 10 cm. A systematic design procedure is used to determine the system parameters. The performance of an optimum, maximum likelihood processor is analysed, which provides the basis for modifying the standard split-gate tracker to achieve improved performance. Bandwidth considerations lead to the recommendation of a full deramp STRETCH pulse compression technique followed by an analog filter bank to separate range returns. The implementation of the recommended technique is examined.

  1. Self-interference of split HOLZ line (SIS-HOLZ) for z-dependent atomic displacement measurement: Theoretical discussion.

    PubMed

    Norouzpour, Mana; Rakhsha, Ramtin; Herring, Rodney

    2017-06-01

    A characteristic of the majority of semiconductors is the presence of lattice strain varying with the nanometer scale. Strain originates from the lattice mismatch between layers of different composition deposited during epitaxial growth. Strain can increase the mobility of the charge carriers by the band gap reduction. So, measuring atomic displacement inside crystals is an important field of interest in semiconductor industry. Among all available transmission electron microscopy techniques offering nano-scale resolution measurements, convergent beam electron diffraction (CBED) patterns show the highest sensitivity to the atomic displacement. Higher Order Laue Zone (HOLZ) lines split by small non-uniform variations of lattice constant allowing to measure the atomic displacement through the crystal. However, it could only reveal the atomic displacement in two dimensions, i.e., within the x-y plane of the thin film of TEM specimen. The z-axis atomic displacement which is along the path of the electron beam has been missing. This information can be obtained by recovering the phase information across the split HOLZ line using the self-interference of the split HOLZ line (SIS-HOLZ). In this work, we report the analytical approach used to attain the phase profile across the split HOLZ line. The phase profile is studied for three different atomic displacement fields in the Si substrate at 80nm away from its interface with Si/Si 0.8 Ge 0.2 superlattices. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Introducing an experimental split-cylinder to study flows with geophysical interest: First steps and first results

    NASA Astrophysics Data System (ADS)

    Rodriguez-Garcia, Jesus O.; Burguete, Javier

    2017-11-01

    A new experimental setup has been developed in order to study rotating flows. Our research is derived from the experiments carried out in our group relating to this kind of flows, and the setup is inspired by the simulations performed by Lopez & Gutierrez-Castillo using a split-cylinder flow. In their work they study the different bifurcations taking place into the flow, among others, finding inertial waves in different configurations of the movement of the split-cylinder. Our setup consists in a split-cylinder in which each half can move in co-rotation or in counter-rotation. Moreover, we can set the rotation velocity of each half independently in order to study these different configurations of the flow. The aspect ratio defined as Γ = H / R can be modified, where H is the internal length of the cylinder and R is its radius. With this setup, we study the flow developed inside the split-cylinder depending on the Reynolds number like the different symmetry-breaking that should appear according to Lopez & Gutierrez-Castillo. To obtain the experimental data we use both laser Doppler velocimetry (LDV) and particle image velocimetry (PIV) techniques. The firsts results got are in the co-rotation case rotating one half faster than the other. We acknowledge support from Spanish Government Grant FIS 2014-54101-P. Jesús O. Rodríguez-García acknowledge research Grant from Asociación de Amigos de la Universidad de Navarra.

  3. Splitting a colon geometry with multiplanar clipping

    NASA Astrophysics Data System (ADS)

    Ahn, David K.; Vining, David J.; Ge, Yaorong; Stelts, David R.

    1998-06-01

    Virtual colonoscopy, a recent three-dimensional (3D) visualization technique, has provided radiologists with a unique diagnostic tool. Using this technique, a radiologist can examine the internal morphology of a patient's colon by navigating through a surface-rendered model that is constructed from helical computed tomography image data. Virtual colonoscopy can be used to detect early forms of colon cancer in a way that is less invasive and expensive compared to conventional endoscopy. However, the common approach of 'flying' through the colon lumen to visually search for polyps is tedious and time-consuming, especially when a radiologist loses his or her orientation within the colon. Furthermore, a radiologist's field of view is often limited by the 3D camera position located inside the colon lumen. We have developed a new technique, called multi-planar geometry clipping, that addresses these problems. Our algorithm divides a complex colon anatomy into several smaller segments, and then splits each of these segments in half for display on a static medium. Multi-planar geometry clipping eliminates virtual colonoscopy's dependence upon expensive, real-time graphics workstations by enabling radiologists to globally inspect the entire internal surface of the colon from a single viewpoint.

  4. Fractional-N phase-locked loop for split and direct automatic frequency control in A-GPS

    NASA Astrophysics Data System (ADS)

    Park, Chester Sungchung; Park, Sungkyung

    2018-07-01

    A low-power mixed-signal phase-locked loop (PLL) is modelled and designed for the DigRF interface between the RF chip and the modem chip. An assisted-GPS or A-GPS multi-standard system includes the DigRF interface and uses the split automatic frequency control (AFC) technique. The PLL circuitry uses the direct AFC technique and is based on the fractional-N architecture using a digital delta-sigma modulator along with a digital counter, fulfilling simple ultra-high-resolution AFC with robust digital circuitry and its timing. Relative to the output frequency, the measured AFC resolution or accuracy is <5 parts per billion (ppb) or on the order of a Hertz. The cycle-to-cycle rms jitter is <6 ps and the typical settling time is <30 μs. A spur reduction technique is adopted and implemented as well, demonstrating spur reduction without employing dithering. The proposed PLL includes a low-leakage phase-frequency detector, a low-drop-out regulator, power-on-reset circuitry and precharge circuitry. The PLL is implemented in a 90-nm CMOS process technology with 1.2 V single supply. The overall PLL draws about 1.1 mA from the supply.

  5. MR Fingerprinting Using The Quick Echo Splitting NMR Imaging Technique

    PubMed Central

    Jiang, Yun; Ma, Dan; Jerecic, Renate; Duerk, Jeffrey; Seiberlich, Nicole; Gulani, Vikas; Griswold, Mark A.

    2016-01-01

    Purpose The purpose of the study is to develop a quantitative method for the relaxation properties with a reduced radio frequency (RF) power deposition by combining Magnetic Resonance Fingerprinting (MRF) technique with Quick Echo Splitting NMR Imaging Technique (QUEST). Methods A QUEST-based MRF sequence was implemented to acquire high order echoes by increasing the gaps between RF pulses. Bloch simulations were used to calculate a dictionary containing the range of physically plausible signal evolutions using a range of T1 and T2 values based on the pulse sequence. MRF-QUEST was evaluated by comparing to the results of spin-echo methods. The SAR of QUEST-MRF was compared to the clinically available methods. Results MRF-QUEST quantifies the relaxation properties with good accuracy at the estimated head Specific Absorption Rate (SAR) of 0.03 W/kg. T1 and T2 values estimated by MRF-QUEST are in good agreement with the traditional methods. Conclusion The combination of the MRF and the QUEST provides an accurate quantification of T1 and T2 simultaneously with reduced RF power deposition. The resulting lower SAR may provide a new acquisition strategy for MRF when RF energy deposition is problematic. PMID:26924639

  6. Study of steel crack resistance under dynamic loading and temperature range 20-300 °C

    NASA Astrophysics Data System (ADS)

    Novikov, S. A.; Pushkov, V. A.

    1996-05-01

    The paper describes an experimental technique to measure crack resistance (plane stress-intensity factor) K1C of structural materials at loading rates up to 2ṡ106MPaṡm1/2ṡs-1 and temperatures 20-300 °C. This technique is based on the known Kolsky method using split Hopkinson bars. The tests were performed using compact WOL-specimens of steel St.3.

  7. Overview of the relevant CFD work at Thiokol Corporation

    NASA Technical Reports Server (NTRS)

    Chwalowski, Pawel; Loh, Hai-Tien

    1992-01-01

    An in-house developed proprietary advanced computational fluid dynamics code called SHARP (Trademark) is a primary tool for many flow simulations and design analyses. The SHARP code is a time dependent, two dimensional (2-D) axisymmetric numerical solution technique for the compressible Navier-Stokes equations. The solution technique in SHARP uses a vectorizable implicit, second order accurate in time and space, finite volume scheme based on an upwind flux-difference splitting of a Roe-type approximated Riemann solver, Van Leer's flux vector splitting, and a fourth order artificial dissipation scheme with a preconditioning to accelerate the flow solution. Turbulence is simulated by an algebraic model, and ultimately the kappa-epsilon model. Some other capabilities of the code are 2-D two-phase Lagrangian particle tracking and cell blockages. Extensive development and testing has been conducted on the 3-D version of the code with flow, combustion, and turbulence interactions. The emphasis here is on the specific applications of SHARP in Solid Rocket Motor design. Information is given in viewgraph form.

  8. Potential-sensing electrochemical atomic force microscopy for in operando analysis of water-splitting catalysts and interfaces

    NASA Astrophysics Data System (ADS)

    Nellist, Michael R.; Laskowski, Forrest A. L.; Qiu, Jingjing; Hajibabaei, Hamed; Sivula, Kevin; Hamann, Thomas W.; Boettcher, Shannon W.

    2018-01-01

    Heterogeneous electrochemical phenomena, such as (photo)electrochemical water splitting to generate hydrogen using semiconductors and/or electrocatalysts, are driven by the accumulated charge carriers and thus the interfacial electrochemical potential gradients that promote charge transfer. However, measurements of the "surface" electrochemical potential during operation are not generally possible using conventional electrochemical techniques, which measure/control the potential of a conducting electrode substrate. Here we show that the nanoscale conducting tip of an atomic force microscope cantilever can sense the surface electrochemical potential of electrocatalysts in operando. To demonstrate utility, we measure the potential-dependent and thickness-dependent electronic properties of cobalt (oxy)hydroxide phosphate (CoPi). We then show that CoPi, when deposited on illuminated haematite (α-Fe2O3) photoelectrodes, acts as both a hole collector and an oxygen evolution catalyst. We demonstrate the versatility of the technique by comparing surface potentials of CoPi-decorated planar and mesoporous haematite and discuss viability for broader application in the study of electrochemical phenomena.

  9. Hydrothermal growth of ZnO nanowire arrays: fine tuning by precursor supersaturation

    DOE PAGES

    Yan, Danhua; Cen, Jiajie; Zhang, Wenrui; ...

    2016-12-20

    In this paper, we develop a technique that fine tunes the hydrothermal growth of ZnO nanowires to address the difficulties in controlling their growth in a conventional one-pot hydrothermal method. In our technique, precursors are separately and slowly supplied with the assistance of a syringe pump, through the entire course of the growth. Compared to the one-pot method, the significantly lowered supersaturation of precursors helps eliminating competitive homogeneous nucleation and improves the reproducibility. The supersaturation degree can be readily tuned by the precursor quantity and injection rate, thus forming ZnO nanowire arrays of various geometries and packing densities in amore » highly controllable fashion. The precise control of ZnO nanowire growth enables systematic studies on the correlation between the material's properties and its morphology. Finally, in this work, ZnO nanowire arrays of various morphologies are studied as photoelectrochemical (PEC) water splitting photoanodes, in which we establish clear correlations between the water splitting performance and the nanowires' size, shape, and packing density.« less

  10. An application of digital image processing techniques to the characterization of liquid petroleum gas (LPG) spray

    NASA Astrophysics Data System (ADS)

    Qi, Y. L.; Xu, B. Y.; Cai, S. L.

    2006-12-01

    To control fuel injection, optimize combustion and reduce emissions for LPG (liquefied petroleum gas) engines, it is necessary and important to understand the characteristics of LPG sprays. The present work investigates the geometry of LPG sprays, including spray tip penetration, spray angle, projected spray area and spray volume, by using schlieren photography and digital image processing techniques. Two types of single nozzle injectors were studied, with the same nozzle diameter, but one with and one without a double-hole flow-split head. A code developed to analyse the results directly from the digitized images is shown to be more accurate and efficient than manual measurement and analysis. Test results show that a higher injection pressure produces a longer spray tip penetration, a larger projected spray area and spray volume, but a smaller spray cone angle. The injector with the double-hole split-head nozzle produces better atomization and shorter tip penetration at medium and late injection times, but longer tip penetration in the early stage.

  11. Spatial mapping and statistical reproducibility of an array of 256 one-dimensional quantum wires

    NASA Astrophysics Data System (ADS)

    Al-Taie, H.; Smith, L. W.; Lesage, A. A. J.; See, P.; Griffiths, J. P.; Beere, H. E.; Jones, G. A. C.; Ritchie, D. A.; Kelly, M. J.; Smith, C. G.

    2015-08-01

    We utilize a multiplexing architecture to measure the conductance properties of an array of 256 split gates. We investigate the reproducibility of the pinch off and one-dimensional definition voltage as a function of spatial location on two different cooldowns, and after illuminating the device. The reproducibility of both these properties on the two cooldowns is high, the result of the density of the two-dimensional electron gas returning to a similar state after thermal cycling. The spatial variation of the pinch-off voltage reduces after illumination; however, the variation of the one-dimensional definition voltage increases due to an anomalous feature in the center of the array. A technique which quantifies the homogeneity of split-gate properties across the array is developed which captures the experimentally observed trends. In addition, the one-dimensional definition voltage is used to probe the density of the wafer at each split gate in the array on a micron scale using a capacitive model.

  12. Mechanical and photoelastic analysis of conventional screws and cannulated screws for sagittal split osteotomy fixation: a comparative study.

    PubMed

    Lima, Cristina Jardelino de; Falci, Saulo Gabriel Moreira; Rodrigues, Danillo Costa; Marchiori, Érica Cristina; Moreira, Roger Willian Fernandes

    2015-12-01

    The aim of the present study was to use mechanical and photoelastic tests to compare the performance of cannulated screws with solid-core screws in sagittal split osteotomy fixation. Ten polyurethane mandibles, with a prefabricated sagittal split ramus osteotomy, were fixed with an L inverted technique and allocated to each group as follows: cannulated screw group (CSG), fixed with three 2.3-cannulated screws; and solid-core screw group (SCSG), fixed with three 2.3-solid-core screws. Vertical linear loading tests were performed. The differences between mean values were analyzed through T test for independent samples. The photoelastic test was carried out using a polariscope. The results revealed differences between the two groups only at 1 mm of displacement, in which the cannulated-screw revealed more resistance. Photoelastic test showed higher stress concentration close to mandibular branch in the solid-core group. Cannulated screws performed better than solid-core ones in a mechanical test at 1-mm displacement and photoelastic tests.

  13. Potential-splitting approach applied to the Temkin-Poet model for electron scattering off the hydrogen atom and the helium ion

    NASA Astrophysics Data System (ADS)

    Yarevsky, E.; Yakovlev, S. L.; Larson, Å; Elander, N.

    2015-06-01

    The study of scattering processes in few body systems is a difficult problem especially if long range interactions are involved. In order to solve such problems, we develop here a potential-splitting approach for three-body systems. This approach is based on splitting the reaction potential into a finite range core part and a long range tail part. The solution to the Schrödinger equation for the long range tail Hamiltonian is found analytically, and used as an incoming wave in the three body scattering problem. This reformulation of the scattering problem makes it suitable for treatment by the exterior complex scaling technique in the sense that the problem after the complex dilation is reduced to a boundary value problem with zero boundary conditions. We illustrate the method with calculations on the electron scattering off the hydrogen atom and the positive helium ion in the frame of the Temkin-Poet model.

  14. In-orbit performance of the ITOS improved attitude control system with Hall generator brushless motor and earth-splitting technique

    NASA Technical Reports Server (NTRS)

    Peacock, W. M.

    1973-01-01

    The National Aeronautics and Space Administration (NASA), launched ITOS-D with an improved attitude control system. A Hall generator brushless dc torque motor replaced the brush dc torque motor on Tiros-M and ITOS-A. Two CO2 attitude horizon sensors and one mirror replaced the four wideband horizon sensors and two mirrors on ITOS-1 and NOAA-1. Redundant pitch-control electronic boxes containing additional electronic circuitry for earth-splitting and brushless motor electronics were used. A method of generating a spacecraft earth-facing side reference for comparison to the time occurrence of the earth-splitting pulse was used to automatically correct pitch-attitude error. A single rotating flywheel, supported by a single bearing, provided gyroscopic stability and the required momentum interchange to keep one side of the satellite facing the earth. Magnetic torquing against the earth's magnetic field eliminated the requirement for expendable propellants which would limit satellite life in orbit.

  15. Application of photon Doppler velocimetry to direct impact Hopkinson pressure bars

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lea, Lewis J., E-mail: ll379@cam.ac.uk; Jardine, Andrew P.

    2016-02-15

    Direct impact Hopkinson pressure bar systems offer many potential advantages over split Hopkinson pressure bars, including access to higher strain rates, higher strains for equivalent striker velocity and system length, lower dispersion, and faster achievement of force equilibrium. Currently, these advantages are gained at the expense of all information about the striker impacted specimen face, preventing the experimental determination of force equilibrium, and requiring approximations to be made on the sample deformation history. In this paper, we discuss an experimental method and complementary data analysis for using photon Doppler velocimetry to measure surface velocities of the striker and output barsmore » in a direct impact bar experiment, allowing similar data to be recorded as in a split bar system. We discuss extracting velocity and force measurements, and the precision of measurements. Results obtained using the technique are compared to equivalent split bar tests, showing improved stress measurements for the lowest and highest strains in fully dense metals, and improvement for all strains in slow and non-equilibrating materials.« less

  16. The rotating spectrometer: Biotechnology for cell separations

    NASA Technical Reports Server (NTRS)

    Noever, David A.

    1991-01-01

    An instrument for biochemical studies, called the rotating spectrometer, separates previously inseparable cell cultures. The rotating spectrometer is intended for use in pharmacological studies which require fractional splitting of heterogeneous cell cultures based on cell morphology and swimming behavior. As a method to separate and concentrate cells in free solution, the rotating method requires active organism participation and can effectively split the large class of organisms known to form spontaneous patterns. Examples include the biochemical star, an organism called Tetrahymena pyriformis. Following focusing in a rotating frame, the separation is accomplished using different radial dependencies of concentrated algal and protozoan species. The focusing itself appears as concentric rings and arises from the coupling between swimming direction and Coriolis forces. A dense cut is taken at varying radii, and extraction is replenished at an inlet. Unlike standard separation and concentrating techniques such as filtration or centrifugation, the instrument is able to separate motile from immotile fractions. For a single pass, typical split efficiencies can reach 200 to 300 percent compared to the inlet concentration.

  17. The rotating spectrometer: New biotechnology for cell separations

    NASA Technical Reports Server (NTRS)

    Noever, David A.; Matsos, Helen C.

    1990-01-01

    An instrument for biochemical studies, called the rotating spectrometer, separates previously inseparable cell cultures. The rotating spectrometer is intended for use in pharmacological studies which require fractional splitting of heterogeneous cell cultures based on cell morphology and swimming behavior. As a method to separate and concentrate cells in free solution, the rotating method requires active organism participation and can effectively split the large class of organisms known to form spontaneous patterns. Examples include the biochemical star, an organism called Tetrahymena pyriformis. Following focusing in a rotated frame, the separation is accomplished using different radial dependencies of concentrated algal and protozoan species. The focusing itself appears as concentric rings and arises from the coupling between swimming direction and Coriolis forces. A dense cut is taken at varying radii and extraction is replenished at an inlet. Unlike standard separation and concentrating techniques such as filtration or centrifugation, the instrument is able to separate motile from immotile fractions. For a single pass, typical split efficiencies can reach 200 to 300 percent compared to the inlet concentration.

  18. Electrodeposition of Ni-Mo alloy coatings for water splitting reaction

    NASA Astrophysics Data System (ADS)

    Shetty, Akshatha R.; Hegde, Ampar Chitharanjan

    2018-04-01

    The present study reports the development of Ni-Mo alloy coatings for water splitting applications, using a citrate bath the inducing effect of Mo (reluctant metal) on electrodeposition, its relationship with their electrocatalytic efficiency were studied. The alkaline water splitting efficiency of Ni-Mo alloy coatings, for both hydrogen evolution reaction (HER) and oxygen evolution reaction were tested using cyclic voltammetry (CV) and chronopotentiometry (CP) techniques. Moreover, the practical utility of these electrode materials were evaluated by measuring the amount of H2 and O2 gas evolved. The variation in electrocatalytic activity with composition, structure, and morphology of the coatings were examined using XRD, SEM, and EDS analyses. The experimental results showed that Ni-Mo alloy coating is the best electrode material for alkaline HER and OER reactions, at lower and higher deposition current densities (c. d.'s) respectively. This behavior is attributed by decreased Mo and increased Ni content of the alloy coating and the number of electroactive centers.

  19. Generation and control of polarization-entangled photons from GaAs island quantum dots by an electric field.

    PubMed

    Ghali, Mohsen; Ohtani, Keita; Ohno, Yuzo; Ohno, Hideo

    2012-02-07

    Semiconductor quantum dots are potential sources for generating polarization-entangled photons efficiently. The main prerequisite for such generation based on biexciton-exciton cascaded emission is to control the exciton fine-structure splitting. Among various techniques investigated for this purpose, an electric field is a promising means to facilitate the integration into optoelectronic devices. Here we demonstrate the generation of polarization-entangled photons from single GaAs quantum dots by an electric field. In contrast to previous studies, which were limited to In(Ga)As quantum dots, GaAs island quantum dots formed by a thickness fluctuation were used because they exhibit a larger oscillator strength and emit light with a shorter wavelength. A forward voltage was applied to a Schottky diode to control the fine-structure splitting. We observed a decrease and suppression in the fine-structure splitting of the studied single quantum dot with the field, which enabled us to generate polarization-entangled photons with a high fidelity of 0.72 ± 0.05.

  20. Surgical Management of Laterognathia in Orthofacial Surgery.

    PubMed

    García Y Sánchez, J M; Gómez Rodríguez, C L; Romero Flores, J

    2017-09-01

    Each year around the world, various surgical procedures are carried out with the goal of correcting laterognathia; both the intraoral vertical ramus osteotomy (IVRO) and bilateral sagittal split ramus osteotomy (OSB) have been the most used techniques in mandibular surgery. These techniques have advantages and disadvantages; for example the advantages of the OSB include: increased coefficient of friction between bony segments, for both the forward and the retroposition, as well as decrease in the time of intermaxillary fixation (IMF). Disadvantages include injury to the inferior alveolar nerve (IAN), hemorrhage, bad split, among others. The advantages of IVRO include decrease of possibility of injury to the IAN, ease of implementation of the technique, a lower incidence of hemorrhage and the short duration of the surgical procedure. Their disadvantages include: lower coefficient of friction between bony segments, requires a relatively long period of IMF. The combination between the techniques of mandibular osteotomy for the correction of minor 10 mm laterognathia is the ideal treatment, since it avoids potential recurrence. We describe two cases of patients with laterognathia greater than 6 mm associated with maxilla deformity, which were treated with combined osteotomies. At Maxillofacial Surgery Service, Specialty Hospital, National Medical Center XXI Century, we describe the advantages and disadvantages, pre and postoperative nosocomial, by comparing them with the reports of the literature. The combination of techniques in the correction of laterognathias greater than 4 mm (smaller than 10 mm) is the ideal treatment, eliminating problems of articular compression, recurrence and damage to the alveolar nerve.

  1. Accelerated high-resolution photoacoustic tomography via compressed sensing

    NASA Astrophysics Data System (ADS)

    Arridge, Simon; Beard, Paul; Betcke, Marta; Cox, Ben; Huynh, Nam; Lucka, Felix; Ogunlade, Olumide; Zhang, Edward

    2016-12-01

    Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue (4D PAT). A particular example is the planar Fabry-Pérot (FP) photoacoustic scanner, which yields high-resolution 3D images but takes several minutes to sequentially map the incident photoacoustic field on the 2D sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant. We demonstrate that combining model-based, variational image reconstruction methods using spatial sparsity constraints with the development of novel PAT acquisition systems capable of sub-sampling the acoustic wave field can dramatically increase the acquisition speed while maintaining a good spatial resolution: first, we describe and model two general spatial sub-sampling schemes. Then, we discuss how to implement them using the FP interferometer and demonstrate the potential of these novel compressed sensing PAT devices through simulated data from a realistic numerical phantom and through measured data from a dynamic experimental phantom as well as from in vivo experiments. Our results show that images with good spatial resolution and contrast can be obtained from highly sub-sampled PAT data if variational image reconstruction techniques that describe the tissues structures with suitable sparsity-constraints are used. In particular, we examine the use of total variation (TV) regularization enhanced by Bregman iterations. These novel reconstruction strategies offer new opportunities to dramatically increase the acquisition speed of photoacoustic scanners that employ point-by-point sequential scanning as well as reducing the channel count of parallelized schemes that use detector arrays.

  2. An AVHRR Cloud Classification Database Typed by Experts

    DTIC Science & Technology

    1993-10-01

    analysis. Naval Research Laboratory, Monterey, CA. 110 pp. Gallaudet , Timothy C. and James J. Simpson, 1991: Automated cloud screening of AVHRR imagery...1987) and Saunders and Kriebel (1988a,b) have used threshold techniques to classify clouds. Gallaudet and Simpson (1991) have used split-and-merge

  3. TWO-DIMENSIONAL MODELING OF AQUIFER REMEDIATION INFLUENCED BY SORPTION NONEQUILIBRIUM AND HYDRAULIC CONDUCTIVITY HETEROGENEITY

    EPA Science Inventory

    A computational model was developed to simulate aquifer remediation by pump and treat for a confined, perfectly stratified aquifer. A split-operator finite element numerical technique was utilized to incorporate flow field heterogeneity and nonequilibrium sorption into a two-dime...

  4. Investigation of Convection and Pressure Treatment with Splitting Techniques

    NASA Technical Reports Server (NTRS)

    Thakur, Siddharth; Shyy, Wei; Liou, Meng-Sing

    1995-01-01

    Treatment of convective and pressure fluxes in the Euler and Navier-Stokes equations using splitting formulas for convective velocity and pressure is investigated. Two schemes - controlled variation scheme (CVS) and advection upstream splitting method (AUSM) - are explored for their accuracy in resolving sharp gradients in flows involving moving or reflecting shock waves as well as a one-dimensional combusting flow with a strong heat release source term. For two-dimensional compressible flow computations, these two schemes are implemented in one of the pressure-based algorithms, whose very basis is the separate treatment of convective and pressure fluxes. For the convective fluxes in the momentum equations as well as the estimation of mass fluxes in the pressure correction equation (which is derived from the momentum and continuity equations) of the present algorithm, both first- and second-order (with minmod limiter) flux estimations are employed. Some issues resulting from the conventional use in pressure-based methods of a staggered grid, for the location of velocity components and pressure, are also addressed. Using the second-order fluxes, both CVS and AUSM type schemes exhibit sharp resolution. Overall, the combination of upwinding and splitting for the convective and pressure fluxes separately exhibits robust performance for a variety of flows and is particularly amenable for adoption in pressure-based methods.

  5. Experimental detection of a Majorana mode in the core of a magnetic vortex inside a topological insulator-superconductor Bi(2)Te(3)/NbSe(2) heterostructure.

    PubMed

    Xu, Jin-Peng; Wang, Mei-Xiao; Liu, Zhi Long; Ge, Jian-Feng; Yang, Xiaojun; Liu, Canhua; Xu, Zhu An; Guan, Dandan; Gao, Chun Lei; Qian, Dong; Liu, Ying; Wang, Qiang-Hua; Zhang, Fu-Chun; Xue, Qi-Kun; Jia, Jin-Feng

    2015-01-09

    Majorana fermions have been intensively studied in recent years for their importance to both fundamental science and potential applications in topological quantum computing. They are predicted to exist in a vortex core of superconducting topological insulators. However, it is extremely difficult to distinguish them experimentally from other quasiparticle states for the tiny energy difference between Majorana fermions and these states, which is beyond the energy resolution of most available techniques. Here, we circumvent the problem by systematically investigating the spatial profile of the Majorana mode and the bound quasiparticle states within a vortex in Bi(2)Te(3) films grown on a superconductor NbSe(2). While the zero bias peak in local conductance splits right off the vortex center in conventional superconductors, it splits off at a finite distance ∼20  nm away from the vortex center in Bi(2)Te(3). This unusual splitting behavior has never been observed before and could be possibly due to the Majorana fermion zero mode. While the Majorana mode is destroyed by the interaction between vortices, the zero bias peak splits as a conventional superconductor again. This work provides self-consistent evidences of Majorana fermions and also suggests a possible route to manipulating them.

  6. Mass Gauging Demonstrator for Any Gravitational Conditions

    NASA Technical Reports Server (NTRS)

    Korman, Valentin (Inventor); Pedersen, Kevin W. (Inventor); Witherow, William K. (Inventor)

    2013-01-01

    The present invention is a mass gauging interferometry system used to determine the volume contained within a tank. By using an optical interferometric technique to determine gas density and/or pressure a much smaller compression volume or higher fidelity measurement is possible. The mass gauging interferometer system is comprised of an optical source, a component that splits the optical source into a plurality of beams, a component that recombines the split beams, an optical cell operatively coupled to a tank, a detector for detecting fringes, and a means for compression. A portion of the beam travels through the optical cell operatively coupled to the tank, while the other beam(s) is a reference.

  7. Localized states in an arbitrarily bent quantum wire (bend-imitating approach)

    NASA Astrophysics Data System (ADS)

    Vakhnenko, Oleksity O.

    1996-02-01

    The bend-imitating matching technique is proposed to simplify the quantum mechanical treatment of singly and multiply bent 2D quantum wires of constant width, arbitrary bending angles, arbitrary bending radii and arbitrary distances between the bends. The spectrum of one-electron localized states and its dependence on the bending angle and the bending radius in a singly bent wire is explicitly calculated. Doubly bent wires are shown to possess doubly split localized states. The splitting energies as a function of the distance between the bends and the bending angles and bending radii have also been obtained. A similar description of bent 3D quantum wires and bent optical fibers is expected to be possible.

  8. Compact ultra wide band microstrip bandpass filter based on multiple-mode resonator and modified complementary split ring resonator.

    PubMed

    Marcotegui, J Antonio; Illescas, Jesús Miguel; Estevez, Aritz; Falcone, Francisco

    2013-01-01

    A new class of broadband microstrip filters for Ultra Wide Band (UWB) applications is proposed. In the design, different stages of parallel-coupled microstrip line and other stages with a Modified Complementary Split Ring Resonator (MCSRR)-a concept proposed here for the first time-are adjusted to obtain the desired response with broadband, sharp rejection, low insertion loss, and low return loss. Full wave simulation results as well as measurement results from fabricated prototypes are presented, showing good agreement. The proposed technique offers a new alternative to implement low-cost high-performance filter devices, applicable to a wide range of communication systems.

  9. Compact Ultra Wide Band Microstrip Bandpass Filter Based on Multiple-Mode Resonator and Modified Complementary Split Ring Resonator

    PubMed Central

    Marcotegui, J. Antonio; Illescas, Jesús Miguel; Estevez, Aritz

    2013-01-01

    A new class of broadband microstrip filters for Ultra Wide Band (UWB) applications is proposed. In the design, different stages of parallel-coupled microstrip line and other stages with a Modified Complementary Split Ring Resonator (MCSRR)—a concept proposed here for the first time—are adjusted to obtain the desired response with broadband, sharp rejection, low insertion loss, and low return loss. Full wave simulation results as well as measurement results from fabricated prototypes are presented, showing good agreement. The proposed technique offers a new alternative to implement low-cost high-performance filter devices, applicable to a wide range of communication systems. PMID:24319366

  10. Crystal-field-driven redox reactions: How common minerals split H2O and CO2 into reduced H2 and C plus oxygen

    NASA Technical Reports Server (NTRS)

    Freund, F.; Batllo, F.; Leroy, R. C.; Lersky, S.; Masuda, M. M.; Chang, S.

    1991-01-01

    It is difficult to prove the presence of molecular H2 and reduced C in minerals containing dissolved H2 and CO2. A technique was developed which unambiguously shows that minerals grown in viciously reducing environments contain peroxy in their crystal structures. The peroxy represent interstitial oxygen atoms left behind when the solute H2O and/or CO2 split off H2 and C as a result of internal redox reactions, driven by the crystal field. The observation of peroxy affirms the presence of H2 and reduced C. It shows that the solid state is indeed an unusual reaction medium.

  11. Ab Initio Calculations of Spin-Orbit Coupling for Heavy-Metal Containing Radicals

    NASA Astrophysics Data System (ADS)

    Cheng, Lan

    2016-06-01

    The perturbative treatment of spin-orbit coupling (SOC) on top of scalar-relativistic calculations is a cost-effective alternative to rigorous fully relativistic calculations. In this work the applicability of the perturbative scheme in the framework of spin-free exact two-component theory is demonstrated with calculations of SO splittings and SOC contributions to molecular properties in small heavy-metal containing radicals, including AuO, AuS, and ThO^+. The equation of motion coupled cluster techniques have been used to accurately account for the electron-correlation effects in these radicals, and basis-set effects are carefully analyzed. The computed results are compared with experimental measurements for SO splittings and dipole moments when available.

  12. Enhancing the Area of a Raman Atom Interferometer Using a Versatile Double-Diffraction Technique

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leveque, T.; Gauguet, A.; Michaud, F.

    2009-08-21

    In this Letter, we demonstrate a new scheme for Raman transitions which realize a symmetric momentum-space splitting of 4(Planck constant/2pi)k, deflecting the atomic wave packets into the same internal state. Combining the advantages of Raman and Bragg diffraction, we achieve a three pulse state labeled an interferometer, intrinsically insensitive to the main systematics and applicable to all kinds of atomic sources. This splitting scheme can be extended to 4N(Planck constant/2pi)k momentum transfer by a multipulse sequence and is implemented on a 8(Planck constant/2pi)k interferometer. We demonstrate the area enhancement by measuring inertial forces.

  13. A note on convergence of solutions of total variation regularized linear inverse problems

    NASA Astrophysics Data System (ADS)

    Iglesias, José A.; Mercier, Gwenael; Scherzer, Otmar

    2018-05-01

    In a recent paper by Chambolle et al (2017 Inverse Problems 33 015002) it was proven that if the subgradient of the total variation at the noise free data is not empty, the level-sets of the total variation denoised solutions converge to the level-sets of the noise free data with respect to the Hausdorff distance. The condition on the subgradient corresponds to the source condition introduced by Burger and Osher (2007 Multiscale Model. Simul. 6 365–95), who proved convergence rates results with respect to the Bregman distance under this condition. We generalize the result of Chambolle et al to total variation regularization of general linear inverse problems under such a source condition. As particular applications we present denoising in bounded and unbounded, convex and non convex domains, deblurring and inversion of the circular Radon transform. In all these examples the convergence result applies. Moreover, we illustrate the convergence behavior through numerical examples.

  14. Analysis of Online Composite Mirror Descent Algorithm.

    PubMed

    Lei, Yunwen; Zhou, Ding-Xuan

    2017-03-01

    We study the convergence of the online composite mirror descent algorithm, which involves a mirror map to reflect the geometry of the data and a convex objective function consisting of a loss and a regularizer possibly inducing sparsity. Our error analysis provides convergence rates in terms of properties of the strongly convex differentiable mirror map and the objective function. For a class of objective functions with Hölder continuous gradients, the convergence rates of the excess (regularized) risk under polynomially decaying step sizes have the order [Formula: see text] after [Formula: see text] iterates. Our results improve the existing error analysis for the online composite mirror descent algorithm by avoiding averaging and removing boundedness assumptions, and they sharpen the existing convergence rates of the last iterate for online gradient descent without any boundedness assumptions. Our methodology mainly depends on a novel error decomposition in terms of an excess Bregman distance, refined analysis of self-bounding properties of the objective function, and the resulting one-step progress bounds.

  15. Matriderm for Management of Scalp Necrosis Following Surgical Treatment of Giant Parietal Encephalocele.

    PubMed

    Vilela, Marcelo D; Pedrosa, Hugo A S; Sampaio, Felipe D; Carneiro, Junia L

    2018-02-01

    Management of encephaloceles is challenging when massive brain herniation is present. In such instances, an expansile cranioplasty may be attempted so as to preserve some herniated brain tissue. Complications such as wound dehiscence, cerebrospinal fluid leak, and scalp necrosis are postoperative concerns. The treatment of scalp necrosis with dural and brain exposure is certainly a challenge due to the complexity of flap techniques in such a young age. Herein we describe the use of a novel technique for the management of a scalp necrosis and dehiscence in an infant. A patient with a giant parietal encephalocele and massive brain herniation underwent an expansile cranioplasty. A large scalp necrosis ensued as a complication and later progressed to a suture dehiscence despite a new surgical intervention, with resultant brain exposure. A scalp reconstruction was subsequently performed using an artificial dermal substitute, laid directly onto the brain, followed by a split-thickness skin graft. We observed a rapid engraftment, without any further complications, with an acceptable cosmetic result in the long-term follow-up. A simple technique, such as the use of an artificial dermal matrix with simultaneous split-thickness skin graft, may be an effective treatment for the repair of scalp defects, even when coverage of exposed brain tissue is necessary, when no other techniques are found to be suitable. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Flush-mounting technique for composite beams

    NASA Technical Reports Server (NTRS)

    Harman, T. C.; Kay, B. F.

    1980-01-01

    Procedure permits mounting of heavy parts to surface of composite beams without appreciably weakening beam web. Web is split and held apart in region where attachment is to be made by lightweight precast foam filler. Bolt hole penetrates foam rather than web, and is secured by barrelnut in transverse bushing through web.

  17. Split My Brain: A Case Study of Seizure Disorder and Brain Function

    ERIC Educational Resources Information Center

    Omarzu, Julia

    2004-01-01

    This case involves a couple deciding whether or not their son should undergo brain surgery to treat a severe seizure disorder. In examining this dilemma, students apply knowledge of brain anatomy and function. They also learn about brain scanning techniques and discuss the plasticity of the brain.

  18. The accuracy, precision and sustainability of different techniques for tablet subdivision: breaking by hand and the use of tablet splitters or a kitchen knife.

    PubMed

    van Riet-Nales, Diana A; Doeve, Myrthe E; Nicia, Agnes E; Teerenstra, Steven; Notenboom, Kim; Hekster, Yechiel A; van den Bemt, Bart J F

    2014-05-15

    Tablets are frequently subdivided to lower the dose, to facilitate swallowing by e.g. children or older people or to save costs. Splitting devices are commonly used when hand breaking is difficult or painful. Three techniques for tablet subdivision were investigated: hand breaking, tablet splitter, kitchen knife. A best case drug (paracetamol), tablet (round, flat, uncoated, 500 mg) and operator (24-year student) were applied. Hundred tablets were subdivided by hand and by three devices of each of the following types: Fit & Healthy, Health Care Logistics, Lifetime, PillAid, PillTool, Pilomat tablet splitter; Blokker kitchen knife. The intra and inter device accuracy, precision and sustainability were investigated. The compliance to (adapted) regulatory requirements was investigated also. The accuracy and precision of hand broken tablets was 104/97% resp. 2.8/3.2% (one part per tablet considered; parts right/left side operator). The right/left accuracies of the splitting devices varied between 60 and 133%; the precisions 4.0 and 29.6%. The devices did not deteriorate over 100-fold use. Only hand broken tablets complied with all regulatory requirements. Health care professionals should realize that tablet splitting may result in inaccurate dosing. Authorities should undertake appropriate measures to assure good function of tablet splitters and, where feasible, to reduce the need for their use. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  19. AGARD Flight Test Techniques Series. Volume 9. Aircraft Exterior Noise Measurement and Analysis Techniques. (Le Bruit a l’Exterieur des Aeronefs: Techniques de Mesure et d’Analyse)

    DTIC Science & Technology

    1991-04-01

    aircraft Fig. 4.6 Airborne test set-up to compare several microphone/nose-cone arrangements for self -noise generation on a glider plane Fig. 4.7 Comparison...of normalized self -noise spectra of ogive-nose-cone equipped condenser-microphones of different diameters F!g. 4.8 Frequency splitting in the noise...output is obtained at the last com-poet ot the sub-system. The electrical respose of the entire system is then the arithmetic Sof the ildividual respnsem

  20. [Applicational evaluation of split tooth extractions of upper molars using piezosurgery].

    PubMed

    Li, D; Guo, C B; Liu, Y; Wang, E B

    2016-02-18

    To evaluate the efficacy of Piezosurgery in split teeth extractions. A single-center, randomized, split-mouth study was performed using a consecutive serious of unrelated healthy patients attending the departing of oral and maxillofacial surgery, Peking University School and Hospital of Stomatology. 40 patients were selected for extraction of maxillary molars without reservation value,splitting or nonvital teeth. They were divided into control (20 patients) and test groups (20 patients) randomly. Surgical treatments for both groups were under local anesthesia. Molar teeth of control group were extracted by common equipments like dental elevators, chisels, forceps, etc. While molar teeth of experimental group were extracted by Piezosurgery, aided with the use of common equipments if needed. Then we compared the duration of surgery, frequency of the usage of chisels, expansion of postoperative bony socket surgical discomfort and postoperative pain between two groups. The average of operation time was (629.5±171.0) s in control group and (456.0±337.2) s in test group. The buccal alveolar bone reduced (1.07±0.64) mm in control group and (1.49±0.61) mm in test group. There was a significant difference between the two groups (P<0.05). The duration of surgery for experimental group was significantly longer than that of the control group, but the change of buccal alveolar bone was lower than the control group. For visual analogue scale (VAS) value of surgical discomfort, expansion of postoperative bony socket and the operative fear rate, there were no significant difference between the two groups (P>0.05). Piezosugery can be better to preserve alveolar bone, reduce trauma and patient's fear. Application of the piezosugery reflect the characteristics of minimally invasive extraction, which has the value of promotion. The Piezosurgery technique have the advantage of reducing change of buccal alveolar bone during the surgery, but a longer surgical time was required when compared with the conventional technique. VAS value of surgical discomfort, expansion of postoperative bony socket and the operative fear rate, there were no significant difference. Minimally invasive tooth extraction technique has good clinical results and high satisfaction. Piezosurgery proved its worth as the instrument adapted to limiting the destruction of bone tissue.

  1. [Applicational evaluation of split tooth extractions of upper molars using piezosurgery].

    PubMed

    Li, D; Guo, C B; Liu, Y; Wang, E B

    2016-08-18

    To evaluate the efficacy of Piezosurgery in split teeth extractions. A single-center, randomized, split-mouth study was performed using a consecutive serious of unrelated healthy patients attending the departing of oral and maxillofacial surgery, Peking University School and Hospital of Stomatology. 40 patients were selected for extraction of maxillary molars without reservation value,splitting or nonvital teeth. They were divided into control (20 patients) and test groups (20 patients) randomly. Surgical treatments for both groups were under local anesthesia. Molar teeth of control group were extracted by common equipments like dental elevators, chisels, forceps, etc. While molar teeth of experimental group were extracted by Piezosurgery, aided with the use of common equipments if needed. Then we compared the duration of surgery, frequency of the usage of chisels, expansion of postoperative bony socket surgical discomfort and postoperative pain between two groups. The average of operation time was (629.5±171.0) s in control group and (456.0±337.2) s in test group. The buccal alveolar bone reduced (1.07±0.64) mm in control group and (1.49±0.61) mm in test group. There was a significant difference between the two groups (P<0.05). The duration of surgery for experimental group was significantly longer than that of the control group, but the change of buccal alveolar bone was lower than the control group. For visual analogue scale (VAS) value of surgical discomfort, expansion of postoperative bony socket and the operative fear rate, there were no significant difference between the two groups (P>0.05). Piezosugery can be better to preserve alveolar bone, reduce trauma and patient's fear. Application of the piezosugery reflect the characteristics of minimally invasive extraction, which has the value of promotion. The Piezosurgery technique have the advantage of reducing change of buccal alveolar bone during the surgery, but a longer surgical time was required when compared with the conventional technique. VAS value of surgical discomfort, expansion of postoperative bony socket and the operative fear rate, there were no significant difference. Minimally invasive tooth extraction technique has good clinical results and high satisfaction. Piezosurgery proved its worth as the instrument adapted to limiting the destruction of bone tissue.

  2. Influence of detector noise and background noise on detection-system

    NASA Astrophysics Data System (ADS)

    Song, Yiheng; Wang, Zhiyong

    2018-02-01

    Study the noise by detectors and background light ,we find that the influence of background noise on the detection is more than that of itself. Therefore, base on the fiber coupled beam splitting technique, the small area detector is used to replace the large area detector. It can achieve high signal-to-noise ratio (SNR) and reduce the speckle interference of the background light. This technique is expected to solve the bottleneck of large field of view and high sensitivity.

  3. Effects of Isotropic and Anisotropic Structure in the Lowermost Mantle on High-Frequency Body Waveforms

    NASA Astrophysics Data System (ADS)

    Parisi, L.; Ferreira, A. M. G.; Ritsema, J.

    2015-12-01

    It has been observed that vertically (SV) and horizontally (SH) polarised S waves crossing the lowermost mantle sometimes are split by a few seconds The splitting of such waves is often interpreted in terms of seismic anisotropy in the D" region. Here we investigate systematically the effects of elastic, anelastic, isotropic and anisotropic structure on shear-wave splitting, including 3-D variations in some of these physical properties. Taking advantage of accurate waveform modeling techniques such as Gemini and the Spectral Element Method we generate three-component theoretical waveforms in a wide set of 1-D and 3-D, isotropic and radially anisotropic earth models, accurate down to a wave period of T~5.6s. Our numerical simulations in isotropic earth models show that the contamination of S waves by other phases can generate an apparent splitting between SH and SV waves. In particular, in the case of very shallow sources, the sS phase can interfere with the direct S phase, resulting in split SH and SV pulses when the SH and SV (or sSH and sSV) waves have different polarity or a substantial amplitude difference. In the case of deep earthquake sources, a positive shear velocity jump at the top of the D" can cause the triplication of S waves and the ScSH and ScSV phases can have different polarity. Thus, when the triplicated S wave is combined with the ScS phase, the resulting SH-ScSH and SV-ScSV phases may seem split. On the other hand, in the absence of a sharp vertical variation in the shear wave velocity, the difference in polarity between ScSH and ScSV can make the SH pulse larger than SV and thus also lead to apparent splitting between these phases. This effect depends on the thickness of the D" and the Vs gradient within it. S waveforms simulated in radially anisotropic models reveal that a radial anisotropy of ξ=1.07 in the D" seems to be necessary to explain the 2-3s of splitting observed in waveforms recorded in Tanzania from an event in the Banda Sea. However, our analysis also shows that other factors such as sharp vertical variations at the top of D" and gradients of Vs and η within the D'' may also affect the observed waveforms. This study suggests that caution should be taken when interpreting SH-SV splitting of deep mantle body waves exclusively in terms of anisotropy in the lowermost mantle.

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu, Yao; Chen, Josephine; Leary, Celeste I.

    Radiation of the low neck can be accomplished using split-field intensity-modulated radiation therapy (sf-IMRT) or extended-field intensity-modulated radiation therapy (ef-IMRT). We evaluated the effect of these treatment choices on target coverage and thyroid and larynx doses. Using data from 14 patients with cancers of the oropharynx, we compared the following 3 strategies for radiating the low neck: (1) extended-field IMRT, (2) traditional split-field IMRT with an initial cord-junction block to 40 Gy, followed by a full-cord block to 50 Gy, and (3) split-field IMRT with a full-cord block to 50 Gy. Patients were planned using each of these 3 techniques.more » To facilitate comparison, extended-field plans were normalized to deliver 50 Gy to 95% of the neck volume. Target coverage was assessed using the dose to 95% of the neck volume (D{sub 95}). Mean thyroid and larynx doses were computed. Extended-field IMRT was used as the reference arm; the mean larynx dose was 25.7 ± 7.4 Gy, and the mean thyroid dose was 28.6 ± 2.4 Gy. Split-field IMRT with 2-step blocking reduced laryngeal dose (mean larynx dose 15.2 ± 5.1 Gy) at the cost of a moderate reduction in target coverage (D{sub 95} 41.4 ± 14 Gy) and much higher thyroid dose (mean thyroid dose 44.7 ± 3.7 Gy). Split-field IMRT with initial full-cord block resulted in greater laryngeal sparing (mean larynx dose 14.2 ± 5.1 Gy) and only a moderately higher thyroid dose (mean thyroid dose 31 ± 8 Gy) but resulted in a significant reduction in target coverage (D{sub 95} 34.4 ± 15 Gy). Extended-field IMRT comprehensively covers the low neck and achieves acceptable thyroid and laryngeal sparing. Split-field IMRT with a full-cord block reduces laryngeal doses to less than 20 Gy and spares the thyroid, at the cost of substantially reduced coverage of the low neck. Traditional 2-step split-field IMRT similarly reduces the laryngeal dose but also reduces low-neck coverage and delivers very high doses to the thyroid.« less

  5. Development and Implementation of a Transport Method for the Transport and Reaction Simulation Engine (TaRSE) based on the Godunov-Mixed Finite Element Method

    USGS Publications Warehouse

    James, Andrew I.; Jawitz, James W.; Munoz-Carpena, Rafael

    2009-01-01

    A model to simulate transport of materials in surface water and ground water has been developed to numerically approximate solutions to the advection-dispersion equation. This model, known as the Transport and Reaction Simulation Engine (TaRSE), uses an algorithm that incorporates a time-splitting technique where the advective part of the equation is solved separately from the dispersive part. An explicit finite-volume Godunov method is used to approximate the advective part, while a mixed-finite element technique is used to approximate the dispersive part. The dispersive part uses an implicit discretization, which allows it to run stably with a larger time step than the explicit advective step. The potential exists to develop algorithms that run several advective steps, and then one dispersive step that encompasses the time interval of the advective steps. Because the dispersive step is computationally most expensive, schemes can be implemented that are more computationally efficient than non-time-split algorithms. This technique enables scientists to solve problems with high grid Peclet numbers, such as transport problems with sharp solute fronts, without spurious oscillations in the numerical approximation to the solution and with virtually no artificial diffusion.

  6. MR fingerprinting using the quick echo splitting NMR imaging technique.

    PubMed

    Jiang, Yun; Ma, Dan; Jerecic, Renate; Duerk, Jeffrey; Seiberlich, Nicole; Gulani, Vikas; Griswold, Mark A

    2017-03-01

    The purpose of the study is to develop a quantitative method for the relaxation properties with a reduced radio frequency (RF) power deposition by combining magnetic resonance fingerprinting (MRF) technique with quick echo splitting NMR imaging technique (QUEST). A QUEST-based MRF sequence was implemented to acquire high-order echoes by increasing the gaps between RF pulses. Bloch simulations were used to calculate a dictionary containing the range of physically plausible signal evolutions using a range of T 1 and T 2 values based on the pulse sequence. MRF-QUEST was evaluated by comparing to the results of spin-echo methods. The specific absorption rate (SAR) of MRF-QUEST was compared with the clinically available methods. MRF-QUEST quantifies the relaxation properties with good accuracy at the estimated head SAR of 0.03 W/kg. T 1 and T 2 values estimated by MRF-QUEST are in good agreement with the traditional methods. The combination of the MRF and the QUEST provides an accurate quantification of T 1 and T 2 simultaneously with reduced RF power deposition. The resulting lower SAR may provide a new acquisition strategy for MRF when RF energy deposition is problematic. Magn Reson Med 77:979-988, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  7. Seismic Anisotropy Beneath Eastern North America: Results from Multi-Event Inversion

    NASA Astrophysics Data System (ADS)

    Li, Y.; Levin, V. L.; Chen, X.

    2017-12-01

    Seismic anisotropy observed from the split core-refracted shear phases reflects upper mantle deformation. To characterize anisotropic signatures beneath eastern North America, we collected observations along a 1300 km long array from James Bay to the Fundy Basin. The averaged splitting parameters of individual sites show uniform fast polarization orientation of 80° and delay times linearly decreasing from 1.0 s in the Appalachians to 0.5 s in the Superior Province. We also see directional variation of fast polarizations at most sites, which is a likely effect of vertical changes in anisotropic properties. For sites with 10 or more observations, we used a multi-event inversion technique to solve for the underlying anisotropic structure. The technique considers the NULL observations from single-event analysis that are excluded from the averaged splitting parameters. For models with a single 100 km thick anisotropic layer with a horizontal fast axis, we find up to 6% of anisotropy in the Appalachian Orogen, equivalent to a splitting delay time of 1.5 s. Anisotropy strength reduces to 1.8% in the Superior Province, equivalent to delay times under 0.5 s. The overall decrease in anisotropic strength is modified by local changes of up to 2%, suggesting small-scale local variations near the surface. Orientations of the fast axes change from 60° in the Appalachian Orogen to 90° in the Superior Province, and are also modulated by local deviations. In the Appalachian Orogen the fast axes are close to the absolute plate motion in a hot-spot reference frame, while those in the Superior Province differ from it by almost 30°. Average values of splitting delays agree well with results of inversions in the Superior Province, and diverge in the Appalachians. Conversely, averaged fast polarizations match inversion results in the Appalachians, and are systematically different in the Superior Province. For an set of sites with recording periods exceeding 5 years, we will test more complicated models of anisotropy, including dipping fast axes and multiple layers. Figure 1. The best fit anisotropic parameters, orientations of fast axes (top) and strength of anisotropy (bottom), assuming a single 100 km thick horizontal layer with a horizontal fast axis. The red line in top represents the absolute plate motion in a hot spot reference frame.

  8. A split-cavity design for the incorporation of a DC bias in a 3D microwave cavity

    NASA Astrophysics Data System (ADS)

    Cohen, Martijn A.; Yuan, Mingyun; de Jong, Bas W. A.; Beukers, Ewout; Bosman, Sal J.; Steele, Gary A.

    2017-04-01

    We report on a technique for applying a DC bias in a 3D microwave cavity. We achieve this by isolating the two halves of the cavity with a dielectric and directly using them as DC electrodes. As a proof of concept, we embed a variable capacitance diode in the cavity and tune the resonant frequency with a DC voltage, demonstrating the incorporation of a DC bias into the 3D cavity with no measurable change in its quality factor at room temperature. We also characterize the architecture at millikelvin temperatures and show that the split cavity design maintains a quality factor Qi ˜ 8.8 × 105, making it promising for future quantum applications.

  9. A boundary element model of the transport of a semi-infinite bubble through a microvessel bifurcation

    NASA Astrophysics Data System (ADS)

    Calderon, Andres J.; Eshpuniyani, Brijesh; Fowlkes, J. Brian; Bull, Joseph L.

    2010-06-01

    Motivated by a developmental gas embolotherapy technique for selective occlusion of blood flow to tumors, we examined the transport of a pressure-driven semi-infinite bubble through a liquid-filled bifurcating channel. Homogeneity of bubble splitting as the bubble passes through a vessel bifurcation affects the degree to which the vascular network near the tumor can be uniformly occluded. The homogeneity of bubble splitting was found to increase with bubble driving pressure and to decrease with increased bifurcation angle. Viscous losses at the bifurcation were observed to affect the bubble speed significantly. The potential for oscillating bubble interfaces to induce flow recirculation and impart high stresses on the vessel endothelium was also observed.

  10. Tuning exciton energy and fine-structure splitting in single InAs quantum dots by applying uniaxial stress

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Su, Dan; Dou, Xiuming; Wu, Xuefei

    2016-04-15

    Exciton and biexciton emission energies as well as excitonic fine-structure splitting (FSS) in single InAs/GaAs quantum dots (QDs) have been continuously tuned in situ in an optical cryostat using a developed uniaxial stress device. With increasing tensile stress, the red shift of excitonic emission is up to 5 nm; FSS decreases firstly and then increases monotonically, reaching a minimum value of approximately 10 μeV; biexciton binding energy decreases from 460 to 106 μeV. This technique provides a simple and convenient means to tune QD structural symmetry, exciton energy and biexciton binding energy and can be used for generating entangled andmore » indistinguishable photons.« less

  11. Applying new seismic analysis techniques to the lunar seismic dataset: New information about the Moon and planetary seismology on the eve of InSight

    NASA Astrophysics Data System (ADS)

    Dimech, J. L.; Weber, R. C.; Knapmeyer-Endrun, B.; Arnold, R.; Savage, M. K.

    2016-12-01

    The field of planetary science is poised for a major advance with the upcoming InSight mission to Mars due to launch in May 2018. Seismic analysis techniques adapted for use on planetary data are therefore highly relevant to the field. The heart of this project is in the application of new seismic analysis techniques to the lunar seismic dataset to learn more about the Moon's crust and mantle structure, with particular emphasis on `deep' moonquakes which are situated half-way between the lunar surface and its core with no surface expression. Techniques proven to work on the Moon might also be beneficial for InSight and future planetary seismology missions which face similar technical challenges. The techniques include: (1) an event-detection and classification algorithm based on `Hidden Markov Models' to reclassify known moonquakes and look for new ones. Apollo 17 gravimeter and geophone data will also be included in this effort. (2) Measurements of anisotropy in the lunar mantle and crust using `shear-wave splitting'. Preliminary measurements on deep moonquakes using the MFAST program are encouraging, and continued evaluation may reveal new structural information on the Moon's mantle. (3) Probabilistic moonquake locations using NonLinLoc, a non-linear hypocenter location technique, using a modified version of the codes designed to work with the Moon's radius. Successful application may provide a new catalog of moonquake locations with rigorous uncertainty information, which would be a valuable input into: (4) new fault plane constraints from focal mechanisms using a novel approach to Bayes' theorem which factor in uncertainties in hypocenter coordinates and S-P amplitude ratios. Preliminary results, such as shear-wave splitting measurements, will be presented and discussed.

  12. The Role of Oceanic Transform Faults in Seafloor Spreading: A Global Perspective From Seismic Anisotropy

    NASA Astrophysics Data System (ADS)

    Eakin, Caroline M.; Rychert, Catherine A.; Harmon, Nicholas

    2018-02-01

    Mantle anisotropy beneath mid-ocean ridges and oceanic transforms is key to our understanding of seafloor spreading and underlying dynamics of divergent plate boundaries. Observations are sparse, however, given the remoteness of the oceans and the difficulties of seismic instrumentation. To overcome this, we utilize the global distribution of seismicity along transform faults to measure shear wave splitting of over 550 direct S phases recorded at 56 carefully selected seismic stations worldwide. Applying this source-side splitting technique allows for characterization of the upper mantle seismic anisotropy, and therefore the pattern of mantle flow, directly beneath seismically active transform faults. The majority of the results (60%) return nulls (no splitting), while the non-null measurements display clear azimuthal dependency. This is best simply explained by anisotropy with a near vertical symmetry axis, consistent with mantle upwelling beneath oceanic transforms as suggested by numerical models. It appears therefore that the long-term stability of seafloor spreading may be associated with widespread mantle upwelling beneath the transforms creating warm and weak faults that localize strain to the plate boundary.

  13. H2 evolution at Si-based metal-insulator-semiconductor photoelectrodes enhanced by inversion channel charge collection and H spillover.

    PubMed

    Esposito, Daniel V; Levin, Igor; Moffat, Thomas P; Talin, A Alec

    2013-06-01

    Photoelectrochemical (PEC) water splitting represents a promising route for renewable production of hydrogen, but trade-offs between photoelectrode stability and efficiency have greatly limited the performance of PEC devices. In this work, we employ a metal-insulator-semiconductor (MIS) photoelectrode architecture that allows for stable and efficient water splitting using narrow bandgap semiconductors. Substantial improvement in the performance of Si-based MIS photocathodes is demonstrated through a combination of a high-quality thermal SiO2 layer and the use of bilayer metal catalysts. Scanning probe techniques were used to simultaneously map the photovoltaic and catalytic properties of the MIS surface and reveal the spillover-assisted evolution of hydrogen off the SiO2 surface and lateral photovoltage driven minority carrier transport over distances that can exceed 2 cm. The latter finding is explained by the photo- and electrolyte-induced formation of an inversion channel immediately beneath the SiO2/Si interface. These findings have important implications for further development of MIS photoelectrodes and offer the possibility of highly efficient PEC water splitting.

  14. Measuring 20-100 T B-fields using Zeeman splitting of sodium emission lines on a 500 kA pulsed power machine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Banasek, J. T., E-mail: jtb254@cornell.edu; Engelbrecht, J. T.; Pikuz, S. A.

    2016-11-15

    We have shown that Zeeman splitting of the sodium (Na) D-lines at 5890 and 5896 Å can be used to measure the magnetic field (B-field) produced in high current pulsed power experiments. We have measured the B-field next to a return current conductor in a hybrid X-pinch experiment near a peak current of about 500 kA. Na is deposited on the conductor and then is desorbed and excited by radiation from the hybrid X-pinch. The D-line emission spectrum implies B-fields of about 20 T with a return current post of 4 mm diameter or up to 120 T with amore » return current wire of 0.455 mm diameter. These measurements were consistent or lower than the expected B-field, thereby showing that basic Zeeman splitting can be used to measure the B-field in a pulsed-power-driven high-energy-density (HED) plasma experiment. We hope to extend these measurement techniques using suitable ionized species to measurements within HED plasmas.« less

  15. Generation and control of polarization-entangled photons from GaAs island quantum dots by an electric field

    PubMed Central

    Ghali, Mohsen; Ohtani, Keita; Ohno, Yuzo; Ohno, Hideo

    2012-01-01

    Semiconductor quantum dots are potential sources for generating polarization-entangled photons efficiently. The main prerequisite for such generation based on biexciton–exciton cascaded emission is to control the exciton fine-structure splitting. Among various techniques investigated for this purpose, an electric field is a promising means to facilitate the integration into optoelectronic devices. Here we demonstrate the generation of polarization-entangled photons from single GaAs quantum dots by an electric field. In contrast to previous studies, which were limited to In(Ga)As quantum dots, GaAs island quantum dots formed by a thickness fluctuation were used because they exhibit a larger oscillator strength and emit light with a shorter wavelength. A forward voltage was applied to a Schottky diode to control the fine-structure splitting. We observed a decrease and suppression in the fine-structure splitting of the studied single quantum dot with the field, which enabled us to generate polarization-entangled photons with a high fidelity of 0.72±0.05. PMID:22314357

  16. TReacLab: An object-oriented implementation of non-intrusive splitting methods to couple independent transport and geochemical software

    NASA Astrophysics Data System (ADS)

    Jara, Daniel; de Dreuzy, Jean-Raynald; Cochepin, Benoit

    2017-12-01

    Reactive transport modeling contributes to understand geophysical and geochemical processes in subsurface environments. Operator splitting methods have been proposed as non-intrusive coupling techniques that optimize the use of existing chemistry and transport codes. In this spirit, we propose a coupler relying on external geochemical and transport codes with appropriate operator segmentation that enables possible developments of additional splitting methods. We provide an object-oriented implementation in TReacLab developed in the MATLAB environment in a free open source frame with an accessible repository. TReacLab contains classical coupling methods, template interfaces and calling functions for two classical transport and reactive software (PHREEQC and COMSOL). It is tested on four classical benchmarks with homogeneous and heterogeneous reactions at equilibrium or kinetically-controlled. We show that full decoupling to the implementation level has a cost in terms of accuracy compared to more integrated and optimized codes. Use of non-intrusive implementations like TReacLab are still justified for coupling independent transport and chemical software at a minimal development effort but should be systematically and carefully assessed.

  17. An Overview of Importance Splitting for Rare Event Simulation

    ERIC Educational Resources Information Center

    Morio, Jerome; Pastel, Rudy; Le Gland, Francois

    2010-01-01

    Monte Carlo simulations are a classical tool to analyse physical systems. When unlikely events are to be simulated, the importance sampling technique is often used instead of Monte Carlo. Importance sampling has some drawbacks when the problem dimensionality is high or when the optimal importance sampling density is complex to obtain. In this…

  18. Evaluation of different screw fixation techniques and screw diameters in sagittal split ramus osteotomy: finite element analysis method.

    PubMed

    Sindel, A; Demiralp, S; Colok, G

    2014-09-01

    Sagittal split ramus osteotomy (SSRO) is used for correction of numerous congenital or acquired deformities in facial region. Several techniques have been developed and used to maintain fixation and stabilisation following SSRO application. In this study, the effects of the insertion formations of the bicortical different sized screws to the stresses generated by forces were studied. Three-dimensional finite elements analysis (FEA) and static linear analysis methods were used to investigate difference which would occur in terms of forces effecting onto the screws and transmitted to bone between different application areas. No significant difference was found between 1·5- and 2-mm screws used in SSRO fixation. Besides, it was found that 'inverted L' application was more successful compared to the others and that was followed by 'L' and 'linear' formations which showed close rates to each other. Few studies have investigated the effect of thickness and application areas of bicortical screws. This study was performed on both advanced and regressed jaws positions. © 2014 John Wiley & Sons Ltd.

  19. Effect of Split Gate Size on the Electrostatic Potential and 0.7 Anomaly within Quantum Wires on a Modulation-Doped GaAs /AlGaAs Heterostructure

    NASA Astrophysics Data System (ADS)

    Smith, L. W.; Al-Taie, H.; Lesage, A. A. J.; Thomas, K. J.; Sfigakis, F.; See, P.; Griffiths, J. P.; Farrer, I.; Jones, G. A. C.; Ritchie, D. A.; Kelly, M. J.; Smith, C. G.

    2016-04-01

    We study 95 split gates of different size on a single chip using a multiplexing technique. Each split gate defines a one-dimensional channel on a modulation-doped GaAs /AlGaAs heterostructure, through which the conductance is quantized. The yield of devices showing good quantization decreases rapidly as the length of the split gates increases. However, for the subset of devices showing good quantization, there is no correlation between the electrostatic length of the one-dimensional channel (estimated using a saddle-point model) and the gate length. The variation in electrostatic length and the one-dimensional subband spacing for devices of the same gate length exceeds the variation in the average values between devices of different lengths. There is a clear correlation between the curvature of the potential barrier in the transport direction and the strength of the "0.7 anomaly": the conductance value of the 0.7 anomaly reduces as the barrier curvature becomes shallower. These results highlight the key role of the electrostatic environment in one-dimensional systems. Even in devices with clean conductance plateaus, random fluctuations in the background potential are crucial in determining the potential landscape in the active device area such that nominally identical gate structures have different characteristics.

  20. Dynamic adaptive chemistry with operator splitting schemes for reactive flow simulations

    NASA Astrophysics Data System (ADS)

    Ren, Zhuyin; Xu, Chao; Lu, Tianfeng; Singer, Michael A.

    2014-04-01

    A numerical technique that uses dynamic adaptive chemistry (DAC) with operator splitting schemes to solve the equations governing reactive flows is developed and demonstrated. Strang-based splitting schemes are used to separate the governing equations into transport fractional substeps and chemical reaction fractional substeps. The DAC method expedites the numerical integration of reaction fractional substeps by using locally valid skeletal mechanisms that are obtained using the directed relation graph (DRG) reduction method to eliminate unimportant species and reactions from the full mechanism. Second-order temporal accuracy of the Strang-based splitting schemes with DAC is demonstrated on one-dimensional, unsteady, freely-propagating, premixed methane/air laminar flames with detailed chemical kinetics and realistic transport. The use of DAC dramatically reduces the CPU time required to perform the simulation, and there is minimal impact on solution accuracy. It is shown that with DAC the starting species and resulting skeletal mechanisms strongly depend on the local composition in the flames. In addition, the number of retained species may be significant only near the flame front region where chemical reactions are significant. For the one-dimensional methane/air flame considered, speed-up factors of three and five are achieved over the entire simulation for GRI-Mech 3.0 and USC-Mech II, respectively. Greater speed-up factors are expected for larger chemical kinetics mechanisms.

  1. Ternary electrocatalysts for oxidizing ethanol to carbon dioxide: making ir capable of splitting C-C bond.

    PubMed

    Li, Meng; Cullen, David A; Sasaki, Kotaro; Marinkovic, Nebojsa S; More, Karren; Adzic, Radoslav R

    2013-01-09

    Splitting the C-C bond is the main obstacle to electrooxidation of ethanol (EOR) to CO(2). We recently demonstrated that the ternary PtRhSnO(2) electrocatalyst can accomplish that reaction at room temperature with Rh having a unique capability to split the C-C bond. In this article, we report the finding that Ir can be induced to split the C-C bond as a component of the ternary catalyst. We characterized and compared the properties of several carbon-supported nanoparticle (NP) electrocatalysts comprising a SnO(2) NP core decorated with multimetallic nanoislands (MM' = PtIr, PtRh, IrRh, PtIrRh) prepared using a seeded growth approach. An array of characterization techniques were employed to establish the composition and architecture of the synthesized MM'/SnO(2) NPs, while electrochemical and in situ infrared reflection absorption spectroscopy studies elucidated trends in activity and the nature of the reaction intermediates and products. Both EOR reactivity and selectivity toward CO(2) formation of several of these MM'/SnO(2)/C electrocatalysts are significantly higher compared to conventional Pt/C and Pt/SnO(2)/C catalysts. We demonstrate that the PtIr/SnO(2)/C catalyst with high Ir content shows outstanding catalytic properties with the most negative EOR onset potential and reasonably good selectivity toward ethanol complete oxidation to CO(2).

  2. Semiconductor-based photoelectrochemical water splitting at the limit of very wide depletion region

    DOE PAGES

    Liu, Mingzhao; Lyons, John L.; Yan, Danhua H.; ...

    2015-11-23

    In semiconductor-based photoelectrochemical (PEC) water splitting, carrier separation and delivery largely relies on the depletion region formed at the semiconductor/water interface. As a Schottky junction device, the trade-off between photon collection and minority carrier delivery remains a persistent obstacle for maximizing the performance of a water splitting photoelectrode. Here, it is demonstrated that the PEC water splitting efficiency for an n-SrTiO 3 (n-STO) photoanode is improved very significantly despite its weak indirect band gap optical absorption (α < 10⁴ cm⁻¹), by widening the depletion region through engineering its doping density and profile. Graded doped n-SrTiO 3 photoanodes are fabricated withmore » their bulk heavily doped with oxygen vacancies but their surface lightly doped over a tunable depth of a few hundred nanometers, through a simple low temperature re-oxidation technique. The graded doping profile widens the depletion region to over 500 nm, thus leading to very efficient charge carrier separation and high quantum efficiency (>70%) for the weak indirect transition. As a result, this simultaneous optimization of the light absorption, minority carrier (hole) delivery, and majority carrier (electron) transport by means of a graded doping architecture may be useful for other indirect band gap photocatalysts that suffer from a similar problem of weak optical absorption.« less

  3. Spatial Distribution of Trehalose Dihydrate Crystallization in Tablets by X-ray Diffractometry.

    PubMed

    Thakral, Naveen K; Yamada, Hiroyuki; Stephenson, Gregory A; Suryanarayanan, Raj

    2015-10-05

    Crystallization of trehalose dihydrate (C12H22O11·2H2O) was induced by storing tablets of amorphous anhydrous trehalose (C12H22O11) at 65% RH (RT). Our goal was to evaluate the advantages and limitations of two approaches of profiling spatial distribution of drug crystallization in tablets. The extent of crystallization, as a function of depth, was determined in tablets stored for different time-periods. The first approach was glancing angle X-ray diffractometry, where the penetration depth of X-rays was modulated by the incident angle. Based on the mass attenuation coefficient of the matrix, the depth of X-ray penetration was calculated as a function of incident angle, which in turn enabled us to "calculate" the extent of crystallization to different depths. In the second approach, the tablets were split into halves and the split surfaces were analyzed directly. Starting from the tablet surface and moving toward the midplane, XRD patterns were collected in 36 "regions", in increments of 0.05 mm. The results obtained by the two approaches were, in general, in good agreement. Additionally, the results obtained were validated by determining the "average" crystallization in the entire tablet by using synchrotron radiation in the transmission mode. The glancing angle method could detect crystallization up to ∼650 μm and had a "surface bias". Being a nondestructive technique, this method will permit repeated analyses of the same tablet at different time points, for example, during a stability study. However, split tablet analyses, while a "destructive" technique, provided comprehensive and unbiased depth profiling information.

  4. Determining the Topology of Integral Membrane Peptides Using EPR Spectroscopy

    PubMed Central

    Inbaraj, Johnson J.; Cardon, Thomas B.; Laryukhin, Mikhail; Grosser, Stuart M.

    2008-01-01

    This paper reports on the development of a new structural biology technique for determining the membrane topology of an integral membrane protein inserted into magnetically aligned phospholipid bilayers (bicelles) using EPR spectroscopy. The nitroxide spin probe, 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid (TOAC) was attached to the pore-lining transmembrane domain (M2δ) of the nicotinic acetylcholine receptor (AChR) and incorporated into a bicelle. The corresponding EPR spectra revealed hyperfine splittings that were highly dependent on the macroscopic orientation of the bicelles with respect to the static magnetic field. The helical tilt of the peptide can be easily calculated using the hyperfine splittings gleaned from the orientational dependent EPR spectra. A helical tilt of 14° was calculated for the M2δ peptide with respect to the bilayer normal of the membrane, which agrees well with previous 15N solid-state NMR studies. The helical tilt of the peptide was verified by simulating the corresponding EPR spectra using the standardized MOMD approach. This new method is advantageous because: (1) bicelle samples are easy to prepare, (2) the helical tilt can be directly calculated from the orientational-dependent hyperfine splitting in the EPR spectra, and (3) EPR spectroscopy is approximately 1000 fold more sensitive than 15N solid-state NMR spectroscopy; thus, the helical tilt of an integral membrane peptide can be determined with only 100 μg of peptide. The helical tilt can be determined more accurately by placing TOAC spin labels at several positions with this technique. PMID:16848493

  5. Pulpal and Periodontal Tissues Changes Associated with Le Fort I and Sagittal Split Ramus Osteotomies: A review

    PubMed Central

    Lazaridis, Konstantinos; Athanasiou, Athanasios E.

    2018-01-01

    Introduction: Le Fort I and sagittal split ramus osteotomies are the most commonly performed orthognathic surgery procedures on the maxilla and mandible, respectively. Techniques: Despite progress in the techniques, these procedures may still be associated with morbidity, expressed as inflammation, inadequate bony union, periodontal damages or in extreme cases even total bone loss. Discussion: Through a comprehensive review of the literature, the influences of maxillary and mandibular surgery on Pulpal Blood Flow (PBF), pulp sensitivity and pulp vitality are examined. Moreover, adverse effects of maxillary surgery on tooth color and periodontal tissues are also reported. The effects had a variety of expression. Concerning maxillary surgery, some studies showed an initial increase in PBF followed by a decrease to the baseline or even lower levels after 1-3 months. Other studies found an initial decrease in PBF followed by an increase soon after. There were also studies that showed no significant PBF changes, in contrast. Conclusion: Concerning mandibular surgery, a recent study showed a decrease in PBF immediately after sagittal split ramus osteotomy. Some authors detected tooth discoloration of maxillary teeth after Le Fort I osteotomy. Root resorption and root injury were also detected, but were of minor significance. Usually, these adverse effects derive from injury of the vessels of the palatal pedicle. This pedicle should be maintained intact for the avoidance of blood flow impairments. In addition, the descending palatine artery should be protected during maxillary surgery procedures in order to maintain the highest possible blood flow on the maxillary teeth. PMID:29456771

  6. Discriminant forest classification method and system

    DOEpatents

    Chen, Barry Y.; Hanley, William G.; Lemmond, Tracy D.; Hiller, Lawrence J.; Knapp, David A.; Mugge, Marshall J.

    2012-11-06

    A hybrid machine learning methodology and system for classification that combines classical random forest (RF) methodology with discriminant analysis (DA) techniques to provide enhanced classification capability. A DA technique which uses feature measurements of an object to predict its class membership, such as linear discriminant analysis (LDA) or Andersen-Bahadur linear discriminant technique (AB), is used to split the data at each node in each of its classification trees to train and grow the trees and the forest. When training is finished, a set of n DA-based decision trees of a discriminant forest is produced for use in predicting the classification of new samples of unknown class.

  7. Loss-compensation technique using a split-spectrum approach for optical fiber air-gap intensity-based sensors

    NASA Astrophysics Data System (ADS)

    Wang, Anbo; Miller, Mark S.; Gunther, Michael F.; Murphy, Kent A.; Claus, Richard O.

    1993-03-01

    A self-referencing technique compensating for fiber losses and source fluctuations in air-gap intensity-based optical fiber sensors is described and demonstrated. A resolution of 0.007 micron has been obtained over a measurement range of 0-250 microns for an intensity-based displacement sensor using this referencing technique. The sensor is shown to have minimal sensitivity to fiber bending losses and variations in the LED input power. A theoretical model for evaluation of step-index multimode optical fiber splice is proposed. The performance of the sensor as a displacement sensor agrees well with the theoretical analysis.

  8. Advances in Surgical Reconstructive Techniques in the Management of Penile, Urethral, and Scrotal Cancer.

    PubMed

    Bickell, Michael; Beilan, Jonathan; Wallen, Jared; Wiegand, Lucas; Carrion, Rafael

    2016-11-01

    This article reviews the most up-to-date surgical treatment options for the reconstructive management of patients with penile, urethral, and scrotal cancer. Each organ system is examined individually. Techniques and discussion for penile cancer reconstruction include Mohs surgery, glans resurfacing, partial and total glansectomy, and phalloplasty. Included in the penile cancer reconstruction section is the use of penile prosthesis in phalloplasty patients after penectomy, tissue engineering in phallic regeneration, and penile transplantation. Reconstruction following treatment of primary urethral carcinoma and current techniques for scrotal cancer reconstruction using split-thickness skin grafts and flaps are described. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Using a Video Split-Screen Technique To Evaluate Streaming Instructional Videos.

    ERIC Educational Resources Information Center

    Gibbs, William J.; Bernas, Ronan S.; McCann, Steven A.

    The Media Center at Eastern Illinois University developed and streamed on the Internet 26 short (one to five minutes) instructional videos about WebCT that illustrated specific functions, including logging-in, changing a password, and using chat. This study observed trainees using and reacting to selections of these videos. It set out to assess…

  10. Lumber potential of 12-year-old Saligna eucalyptus trees in Hawaii

    Treesearch

    Roger G. Skolmen

    1974-01-01

    The sawtimber potential of 12-year-old Eucalyptus saligna Sm. trees grown in Maui, Hawaii, was studied by using simple field techniques. Lumber manufactured from the trees was predominantly of low grade, but had lower average density than wood from older trees, and therefore was more desirable. Logs end-split badly, and sawed with the usually...

  11. Eccentric superconducting RF cavity separator structure

    DOEpatents

    Aggus, John R.; Giordano, Salvatore T.; Halama, Henry J.

    1976-01-01

    Accelerator apparatus having an eccentric-shaped, iris-loaded deflecting cavity for an rf separator for a high energy high momentum, charged particle accelerator beam. In one embodiment, the deflector is superconducting, and the apparatus of this invention provides simplified machining and electron beam welding techniques. Model tests have shown that the electrical characteristics provide the desired mode splitting without adverse effects.

  12. Numerical and analytical modeling of the end-loaded split (ELS) test specimens made of multi-directional coupled composite laminates

    NASA Astrophysics Data System (ADS)

    Samborski, Sylwester; Valvo, Paolo S.

    2018-01-01

    The paper deals with the numerical and analytical modelling of the end-loaded split test for multi-directional laminates affected by the typical elastic couplings. Numerical analysis of three-dimensional finite element models was performed with the Abaqus software exploiting the virtual crack closure technique (VCCT). The results show possible asymmetries in the widthwise deflections of the specimen, as well as in the strain energy release rate (SERR) distributions along the delamination front. Analytical modelling based on a beam-theory approach was also conducted in simpler cases, where only bending-extension coupling is present, but no out-of-plane effects. The analytical results matched the numerical ones, thus demonstrating that the analytical models are feasible for test design and experimental data reduction.

  13. Stability of seasonal influenza vaccines investigated by spectroscopy and microscopy methods.

    PubMed

    Patois, E; Capelle, M A H; Gurny, R; Arvinte, T

    2011-10-06

    The stability of different seasonal influenza vaccines was investigated by spectroscopy and microscopy methods before and after the following stress-conditions: (i) 2 and 4 weeks storage at 25°C, (ii) 1 day storage at 37°C and (iii) one freeze-thaw cycle. The subunit vaccine Influvac (Solvay Pharma) and the split vaccine Mutagrip (Sanofi Pasteur) were affected by all stresses. The split vaccine Fluarix (GlaxoSmithKline) was affected only by storage at 25°C. The virosomal vaccine Inflexal V (Berna Biotech) was stable after the temperature stresses but aggregated after one freeze-thaw cycle. This study provides new insights into commercial vaccines of low antigen concentration and highlights the importance of using multiple techniques to assess vaccine stability. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. Observation of Spin Hall Effect in Photon Tunneling via Weak Measurements

    PubMed Central

    Zhou, Xinxing; Ling, Xiaohui; Zhang, Zhiyou; Luo, Hailu; Wen, Shuangchun

    2014-01-01

    Photonic spin Hall effect (SHE) manifesting itself as spin-dependent splitting escapes detection in previous photon tunneling experiments due to the fact that the induced beam centroid shift is restricted to a fraction of wavelength. In this work, we report on the first observation of this tiny effect in photon tunneling via weak measurements based on preselection and postselection technique on the spin states. We find that the spin-dependent splitting is even larger than the potential barrier thickness when spin-polarized photons tunneling through a potential barrier. This photonic SHE is attributed to spin-redirection Berry phase which can be described as a consequence of the spin-orbit coupling. These findings provide new insight into photon tunneling effect and thereby offer the possibility of developing spin-based nanophotonic applications. PMID:25487043

  15. Comments regarding two upwind methods for solving two-dimensional external flows using unstructured grids

    NASA Technical Reports Server (NTRS)

    Kleb, W. L.

    1994-01-01

    Steady flow over the leading portion of a multicomponent airfoil section is studied using computational fluid dynamics (CFD) employing an unstructured grid. To simplify the problem, only the inviscid terms are retained from the Reynolds-averaged Navier-Stokes equations - leaving the Euler equations. The algorithm is derived using the finite-volume approach, incorporating explicit time-marching of the unsteady Euler equations to a time-asymptotic, steady-state solution. The inviscid fluxes are obtained through either of two approximate Riemann solvers: Roe's flux difference splitting or van Leer's flux vector splitting. Results are presented which contrast the solutions given by the two flux functions as a function of Mach number and grid resolution. Additional information is presented concerning code verification techniques, flow recirculation regions, convergence histories, and computational resources.

  16. Visible near-infrared light scattering of single silver split-ring structure made by nanosphere lithography.

    PubMed

    Okamoto, Toshihiro; Fukuta, Tetsuya; Sato, Shuji; Haraguchi, Masanobu; Fukui, Masuo

    2011-04-11

    We succeeded in making a silver split-ring (SR) structure of approximately 130 nm in diameter on a glass substrate using a nanosphere lithography technique. The light scattering spectrum in visible near-infrared region of a single, isolated SR was measured using a microscope spectroscopy optical system. The electromagnetic field enhancement spectrum and distribution of the SR structure were simulated by the finite-difference time-domain method, and the excitation modes were clarified. The long wavelength peak in the light scattering spectra corresponded to a fundamental LC resonance mode excited by an incident electric field. It was shown that a single SR structure fabricated as abovementioned can operate as a resonator and generate a magnetic dipole. © 2011 Optical Society of America

  17. Calculation of the vibrational excited states of malonaldehyde and their tunneling splittings with the multi-configuration time-dependent Hartree method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schröder, Markus, E-mail: Markus.Schroeder@pci.uni-heidelberg.de; Meyer, Hans-Dieter, E-mail: Hans-Dieter.Meyer@pci.uni-heidelberg.de

    2014-07-21

    We report energies and tunneling splittings of vibrational excited states of malonaldehyde which have been obtained using full dimensional quantum mechanical calculations. To this end we employed the multi configuration time-dependent Hartree method. The results have been obtained using a recently published potential energy surface [Y. Wang, B. J. Braams, J. M. Bowman, S. Carter, and D. P. Tew, J. Chem. Phys. 128, 224314 (2008)] which has been brought into a suitable form by a modified version of the n-mode representation which was used with two different arrangements of coordinates. The relevant terms of the expansion have been identified withmore » a Metropolis algorithm and a diffusion Monte-Carlo technique, respectively.« less

  18. Upper Mantle Seismic Anisotropy Beneath West Antarctica from Shear Wave Splitting Analysis of POLENET/ANET Data

    NASA Astrophysics Data System (ADS)

    Accardo, N.; Wiens, D. A.; Hernandez, S.; Aster, R. C.; Nyblade, A.; Anandakrishnan, S.; Huerta, A. D.; Wilson, T. J.

    2011-12-01

    We constrain azimuthal anisotropy in the Antarctic upper mantle using shear wave splitting parameters obtained from teleseismic SKS, SKKS, and PKS phases recorded at 30 broad-band seismometers deployed in West Antarctica, and the Transantarctic Mountains as a part of POLENET/ANET. The first seismometers were deployed in late 2007 and additional seismometers were deployed in 2008 and 2009. The seismometers generally operate year-round using solar power, insulated boxes, and either rechargeable AGM or primary lithium batteries. We used an eigenvalue technique to linearize the rotated and shifted shear wave particle motions and determine the best splitting parameters. Robust windows around the individual phases were chosen using the Teanby cluster-analysis algorithm. We visually inspected all results and assigned a quality rating based on factors including signal-to-noise ratios, particle motions, and error contours. The best results for each station were then stacked to get an average splitting direction and delay time. The delay times range from 0.33 to 1.33 s, but generally average about 1 s. We conclude that the splitting results from anisotropy in the upper mantle, since the large splitting times cannot be accumulated in the relatively thin crust (20-30 km) of the region. Overall, fast directions in West Antarctica are at large angles to the direction of Antarctic absolute plate motion in either hotspot or no-net rotation frameworks, showing that the anisotropic fabric does not result from shear associated with the motion of Antarctica over the mantle. The West Antarctic fast directions are also much different than those found in East Antarctica by previous studies. We suggest that the East Antarctic splitting results from anisotropy frozen into the cold cratonic continental lithosphere, whereas West Antarctic splitting is related to Cenozoic tectonism. Stations within the West Antarctic Rift System (WARS), a region of Cenozoic extension, show fast directions subparallel to the inferred WARS extension direction. Stations located in the Ellsworth-Whitmore Mountains (EWM) show fast directions parallel to those found within WARS. Furthermore, results from WARS and from EWM all show relatively large splitting times of 0.6 - 1.33 s. These results suggest upper mantle anisotropy that results from mantle flow and deformation related to the extensional deformation of the region. Two stations were installed in the Pensacola Mountains which are located grid-north of the EWM. The results from this region deviate from the dominant fast orientation seen in WARS but appear to be approximately perpendicular to the strike of the mountain range. Stations in Marie Byrd Land (MBL) show inconsistent fast directions and a wide range of delay times (0.3 - 0.9 s), perhaps as a result of complex mantle fabric related to a possible MBL hotspot.

  19. Comparison of the columnar-thin-film and vacuum-metal-deposition techniques to develop sebaceous fingermarks on nonporous substrates.

    PubMed

    Williams, Stephanie F; Pulsifer, Drew P; Shaler, Robert C; Ramotowski, Robert S; Brazelle, Shelly; Lakhtakia, Akhlesh

    2015-03-01

    Both the columnar-thin-film (CTF) and the vacuum-metal-deposition (VMD) techniques for visualizing sebaceous fingermarks require the deposition of a material thereon in a vacuum chamber. Despite that similarity, there are many differences between the two techniques. The film deposited with the CTF technique has a columnar morphology, but the film deposited with the VMD technique comprises discrete islands. A split-print methodology on a variety of fingermarked substrates was used to determine that the CTF technique is superior for developing fingermarks on clear sandwich bags and partial bloody fingermarks on stainless steel. Both techniques are similar in their ability to develop fingermarks on glass but the CTF technique yields higher contrast. The VMD technique is superior for developing fingermarks on white grocery bags and the smooth side of Gloss Finish Scotch Multitask(™) tape. Neither technique worked well for fingermarks on black garbage bags. © 2014 American Academy of Forensic Sciences.

  20. Advanced stitching technology

    NASA Technical Reports Server (NTRS)

    Scardino, Frank L.

    1992-01-01

    In the design of textile composites, the selection of materials and constructional techniques must be matched with product performance, productivity, and cost requirements. Constructional techniques vary. A classification of various textile composite systems is given. In general, the chopped fiber system is not suitable for structural composite applications because of fiber discontinuity, uncontrolled fiber orientation and a lack of fiber integration or entanglement. Linear filament yarn systems are acceptable for structural components which are exposed to simple tension in their applications. To qualify for more general use as structural components, filament yarn systems must be multi-directionally positioned. With the most sophisticated filament winding and laying techniques, however, the Type 2 systems have limited potential for general load-bearing applications because of a lack of filament integration or entanglement, which means vulnerability to splitting and delamination among filament layers. The laminar systems (Type 3) represented by a variety of simple fabrics (woven, knitted, braided and nonwoven) are especially suitable for load-bearing panels in flat form and for beams in a roled up to wound form. The totally integrated, advanced fabric system (Type 4) are thought to be the most reliable for general load-bearing applications because of fiber continuity and because of controlled multiaxial fiber orientation and entanglement. Consequently, the risk of splitting and delamination is minimized and practically omitted. Type 4 systems can be woven, knitted, braided or stitched through with very special equipment. Multiaxial fabric technologies are discussed.

  1. Use of an ultra-clean sampling technique with inductively coupled plasma-mass spectrometry to determine trace-element concentrations in water from the Kirkwood-Cohansey Aquifer system, coastal plain, New Jersey

    USGS Publications Warehouse

    Ivahnenko, Tamara; Szabo, Zoltan; Hall, G.S.

    1996-01-01

    Water samples were collected during 1993 from 22 public supply wells screened in the Kirkwood-Cohansey aquifer system; concentrations of 18 trace elements were determined primarily by using inductively coupled plasma-mass spectrometry (ICP-MS) techniques, though graphite furnace atomic adsorption, hydride generation, and cold- vapor flameless atomic adsorption techniques were used for thallium, arsenic, and mercury, respectively, at the U.S. Geological Survey (USGS) National Water Quality Laboratory (NWQL). In addition, laboratory measurements of alkalinity and turbidity were made. The ground-water samples were collected by using ultra-clean sampling protocols developed by the USGS for collecting ground-water samples in areas with water containing low concentrations of trace elements. This technique is based on recently gained experience in sampling surface water for these elements. Field parameters (water temperature, specific conductance, pH, and dissolved-oxygen concentration) were monitored prior to sample collection. Three equipment blanks were collected to ensure that low-level trace-element contamination did not occur during sample collection. One split sample and a commercially- prepared reference standard were submitted to the NWQL o evaluate laboratory precision and accuracy, respectively. Trace-element concentrations in 10 sample splits and one equipment blank were also determined at the Rutgers University Chemistry Department laboratory. Results of the ICP-MS analyses and cold vapor flameless atomic absorption indicated that five trace elements-- cobalt, copper, lead, mercury, and nickel--were detectable in low concentrations (<0.1-29 mg/L) in most of the samples from the 22 wells, and four elements--aluminum, barium, manganese and zinc--were detected in higher concentrations than the other elements (30-710 mg/L for aluminum; 4-180 mg/L for barium, manganese, and zinc). The remaining nine trace elements were present in concentrations consistently lower than the minimum reporting limit. Turbidity was low (less than 1 nephelometric turbidity unit (NTU)), indicating that the trace-element concentrations were present in the dissolved phase and ideally would be reproducible in the absence of highly variable concentrations of particulates. The concentration of lead in one sample exceeded the U.S. Environmental Protection Agency (USEPA) action level of 15 mg/L; concentrations ranged from <1 to 16 mg/L. Mercury was frequently detected; concentrations ranged from <0.1 to 1.1 mg/L but did not exceed the USEPA maximum contaminant level. Results of analyses of the equipment blanks indicated that samples collected by using the new ultra-clean sampling protocols were free of low-level (< 1mg/L) trace-element contamination. The analysis of the split sample sent to the NWQL had a difference of 5 percent or less for all constituents except aluminum, for which the analysis had a difference of 10 percent. Results of ICP-MS analyses of split water samples sent to the Rutgers University Chemistry Department laboratory were, in general, in good agreement (within 10 percent) with those of the NWQL. Results of the analysis of the commercial standard agreed (within 5 percent) with the known concentrations of the trace elements. The quality-assurance data (three blanks, one split sample, and one standard), although not statistically evaluated because of the small data set, indicate that the measured trace-element concentrations are precise and accurate and that the samples were free of contamination at the microgram-per-liter level of contamination.

  2. Magnetic Photon Splitting: The S-Matrix Formulation in the Landau Representation

    NASA Technical Reports Server (NTRS)

    Baring, Matthew G.

    1999-01-01

    Calculations of reaction rates for the third-order QED process of photon splitting gamma yields gamma.gamma in strong magnetic fields traditionally have employed either the effective Lagrangian method or variants of Schwinger's proper-time technique. Recently, Mentzel, Berg and Wunner [1] presented an alternative derivation via an S-matrix formulation in the Landau representation. Advantages of such a formulation include the ability to compute rates near pair resonances above pair threshold. This paper presents new developments of the Landau representation formalism as applied to photon splitting, providing significant, advances beyond the work of [1] by summing over the spin quantum numbers of the electron propagators, and analytically integrating over the component of momentum of the intermediate states that is parallel to field. The ensuing tractable expressions for the scattering amplitudes are satisfyingly compact, and of an appearance familiar to S-matrix theory applications. Such developments can facilitate numerical computations of splitting considerably both below and above pair threshold. Specializations to two regimes of interest are obtained, namely the limit of highly supercritical fields and the domain where photon energies are far inferior to that for the threshold of single-photon pair creation. In particular, for the first time the low-frequency amplitudes are simply expressed in terms of the Gamma function, its integral and its derivatives. In addition, the equivalence of the asymptotic forms in these two domains to extant results from effective Lagrangian/proper- time formulations is demonstrated.

  3. Combining split-beam and dual-frequency identification sonars to estimate abundance of anadromous fishes in the Roanoke River, North Carolina

    USGS Publications Warehouse

    Hughes, Jacob B.; Hightower, Joseph E.

    2015-01-01

    Riverine hydroacoustic techniques are an effective method for evaluating abundance of upstream migrating anadromous fishes. To use these methods in the Roanoke River, North Carolina, at a wide site with uneven bottom topography, we used a combination of split-beam sonar and dual-frequency identification sonar (DIDSON) deployments. We aimed a split-beam sonar horizontally to monitor midchannel and near-bottom zones continuously over the 3-month spring monitoring periods in 2010 and 2011. The DIDSON was rotated between seven cross-channel locations (using a vertical aim) and nearshore regions (using horizontal aims). Vertical deployment addressed blind spots in split-beam coverage along the bottom and provided reliable information about the cross-channel and vertical distributions of upstream migrants. Using a Bayesian framework, we modeled sonar counts within four cross-channel strata and apportioned counts by species using species proportions from boat electrofishing and gill netting. Modeled estimates (95% credible intervals [CIs]) of total upstream migrants in 2010 and 2011 were 2.5 million (95% CI, 2.4–2.6 million) and 3.6 million (95% CI, 3.4–3.9 million), respectively. Results indicated that upstream migrants are extremely shore- and bottom-oriented, suggesting nearshore DIDSON monitoring improved the accuracy and precision of our estimates. This monitoring protocol and model may be widely applicable to river systems regardless of their cross-sectional width or profile.

  4. Design and optimization of cascaded DCG based holographic elements for spectrum-splitting PV systems

    NASA Astrophysics Data System (ADS)

    Wu, Yuechen; Chrysler, Benjamin; Pelaez, Silvana Ayala; Kostuk, Raymond K.

    2017-09-01

    In this work, the technique of designing and optimizing broadband volume transmission holograms using dichromate gelatin (DCG) is summarized for solar spectrum-splitting application. Spectrum splitting photovoltaic system uses a series of single bandgap PV cells that have different spectral conversion efficiency properties to more fully utilize the solar spectrum. In such a system, one or more high performance optical filters are usually required to split the solar spectrum and efficiently send them to the corresponding PV cells. An ideal spectral filter should have a rectangular shape with sharp transition wavelengths. DCG is a near ideal holographic material for solar applications as it can achieve high refractive index modulation, low absorption and scattering properties and long-term stability to solar exposure after sealing. In this research, a methodology of designing and modeling a transmission DCG hologram using coupled wave analysis for different PV bandgap combinations is described. To achieve a broad diffraction bandwidth and sharp cut-off wavelength, a cascaded structure of multiple thick holograms is described. A search algorithm is also developed to optimize both single and two-layer cascaded holographic spectrum splitters for the best bandgap combinations of two- and three-junction SSPV systems illuminated under the AM1.5 solar spectrum. The power conversion efficiencies of the optimized systems under the AM1.5 solar spectrum are then calculated using the detailed balance method, and shows an improvement compared with tandem structure.

  5. X-ray Spectropolarimetry of Z-pinch Plasmas with a Single-Crystal Technique

    NASA Astrophysics Data System (ADS)

    Wallace, Matt; Haque, Showera; Neill, Paul; Pereira, Nino; Presura, Radu

    2017-10-01

    When directed beams of energetic electrons exist in a plasma the resulting x-rays emitted by the plasma can be partially polarized. This makes plasma x-ray polarization spectroscopy, spectropolarimetry, useful for revealing information about the anisotropy of the electron velocity distribution. X-ray spectropolarimetry has indeed been used for this in both space and laboratory plasmas. X-ray polarization measurements are typically performed employing two crystals, both at a 45° Bragg angle. A single-crystal spectropolarimeter can replace two crystal schemes by utilizing two matching sets of internal planes for polarization-splitting. The polarization-splitting planes diffract the incident x-rays into two directions that are perpendicular to each other and the incident beam as well, so the two sets of diffracted x-rays are linearly polarized perpendicularly to each other. An X-cut quartz crystal with surface along the [11-20] planes and a paired set of [10-10] planes in polarization-splitting orientation is now being used on aluminum z-pinches at the University of Nevada, Reno. Past x-ray polarization measurements have been reserved for point-like sources. Recently a slotted collimating aperture has been used to maintain the required geometry for polarization-splitting enabling the spectropolarimetry of extended sources. The design of a single-crystal x-ray spectropolarimeter and experimental results will be presented. Work was supported by U.S. DOE, NNSA Grant DE-NA0001834 and cooperative agreement DE-FC52-06NA27616.

  6. Microbubble transport through a bifurcating vessel network with pulsatile flow.

    PubMed

    Valassis, Doug T; Dodde, Robert E; Esphuniyani, Brijesh; Fowlkes, J Brian; Bull, Joseph L

    2012-02-01

    Motivated by two-phase microfluidics and by the clinical applications of air embolism and a developmental gas embolotherapy technique, experimental and theoretical models of microbubble transport in pulsatile flow are presented. The one-dimensional time-dependent theoretical model is developed from an unsteady Bernoulli equation that has been modified to include viscous and unsteady effects. Results of both experiments and theory show that roll angle (the angle the plane of the bifurcating network makes with the horizontal) is an important contributor to bubble splitting ratio at each bifurcation within the bifurcating network. When compared to corresponding constant flow, pulsatile flow was shown to produce insignificant changes to the overall splitting ratio of the bubble despite the order one Womersley numbers, suggesting that bubble splitting through the vasculature could be modeled adequately with a more modest constant flow model. However, bubble lodging was affected by the flow pulsatility, and the effects of pulsatile flow were evident in the dependence of splitting ratio of bubble length. The ability of bubbles to remain lodged after reaching a steady state in the bifurcations is promising for the effectiveness of gas embolotherapy to occlude blood flow to tumors, and indicates the importance of understanding where lodging will occur in air embolism. The ability to accurately predict the bubble dynamics in unsteady flow within a bifurcating network is demonstrated and suggests the potential for bubbles in microfluidics devices to encode information in both steady and unsteady aspects of their dynamics.

  7. Treatment of osteoarthritis of the first carpometacarpal joint by resection-suspension-interposition arthoplasty using the split abductor pollicis longus tendon.

    PubMed

    Harenberg, P S; Jakubietz, M G; Jakubietz, R G; Schmidt, K; Meffert, R H

    2013-02-01

    Reduction of pain and gain of functionality in symptomatic osteoarthritis of the first carpometacarpal joint. Idiopathic, rheumatic, or posttraumatic osteoarthritis of the first carpometacarpal joint. RELATIVE CONTRAINDICATIONS: Poor general condition, poor condition of the hand's soft tissue/skin, chronic regional pain syndrome, current or recent infections of the hand, heavy manual labor (decision on a by-case basis). Supine position, hand pronated or slightly tilted. Upper arm tourniquet (Esmarch's method). Loupe magnification. Incision over the first extensor compartment. Exposure and incision of the thumb's basal joint. Resection of the trapezium. Exposure of the abductor pollicis longus (APL) tendon. Longitudinal split of the tendon harvesting the distally based ulnar part of the tendon. The split APL tendon is wrapped around the flexor carpi radialis (FCR) muscle tendon, suturing it to the tendon and back to itself. The rest of the split APL tendon is placed into the gap between the scaphoid and the first metacarpal bone, which is followed by wound closure. Plaster cast (thumb abduction splint) for 4 weeks. Stable commercially available wrist brace for at least 2 more weeks. There were no significant differences between the FCR arthroplasty (Epping's method) and the APL arthroplasty (Wulle's technique) regarding pain (visual analog scale), disability/usability (DASH score), or range of motion. Patients who had undergone APL arthroplasty showed significantly better grip and pinch strength. Furthermore, the operating time was significantly shorter and scars were significantly smaller in APL arthroplasty.

  8. Seismic anisotropy of the crust and upper mantle in central Tibetan Plateau revealed by shear-wave splitting

    NASA Astrophysics Data System (ADS)

    Wu, C.; Tian, X.; Xu, T.; Liang, X.; Chen, Y.; Teng, J.

    2017-12-01

    Seismic anisotropy that results from deformation of the materials in the Earth is essentially important for understanding the deformation styles at different depths. In the central Tibetan Plateau the shear wave splitting measurements of local S-wave, Pms and SKS phases were calculated applying the broadband seismic data of SANDWICH array, and the anisotropy features of the crust and upper mantle were displayed. SKS splitting results show that the study area is strongly anisotropic as a whole. The average splitting parameters are 65.2°/1.28 s, and there are 17 stations existing individual splitting results larger than 2.0 s. The southeastern part is weakly anisotropic with average splitting parameters 61.0°/0.64 s. Applying spatial coherence technique the optimal depth of the source of anisotropy is 130 160 km, located in the asthenosphere. The subducting Indian plate advancing in NE direction and rigid blocks such as Qaidam basin obstructing in the north cause NEE direction asthenospheric flow which produces the anisotropy. The weak anisotropy of southeastern part is corresponding to the low velocity anomalies in the upper mantle, which may be attributed to local upwelling of asthenosphere from the slab tearing region. The crust media also make contribution to the strong anisotropy. S-wave splitting results which reflect upper crust anisotropy show that the average parameters of three stations in western part are 60.4°/1.53 ms/km, and those of two stations in eastern part are 10.9°/4.64 ms/km. The principle compressive stress controlled by structures varies from NE in the west to nearly NS in the east. Under the assumption that the thickness of upper crust is 20 km, the delay time of upper crust is smaller than 0.1 s. Whole crust anisotropy is obtained by calculating receiver functions and fitting the variation of arrival times of Pms phases with the backazimuths. The fast directions are NE-EW direction with average value 76.4°, nearly consistent with SKS fast directions, and the average delay time is about 0.5 s. The source of crust anisotropy mainly comes from middle-lower crust, which is possibly related to middle-lower crust flow.

  9. Real-time three-dimensional imaging of epidermal splitting and removal by high-definition optical coherence tomography.

    PubMed

    Boone, Marc; Draye, Jean Pierre; Verween, Gunther; Pirnay, Jean-Paul; Verbeken, Gilbert; De Vos, Daniel; Rose, Thomas; Jennes, Serge; Jemec, Gregor B E; Del Marmol, Véronique

    2014-10-01

    While real-time 3-D evaluation of human skin constructs is needed, only 2-D non-invasive imaging techniques are available. The aim of this paper is to evaluate the potential of high-definition optical coherence tomography (HD-OCT) for real-time 3-D assessment of the epidermal splitting and decellularization. Human skin samples were incubated with four different agents: Dispase II, NaCl 1 M, sodium dodecyl sulphate (SDS) and Triton X-100. Epidermal splitting, dermo-epidermal junction, acellularity and 3-D architecture of dermal matrices were evaluated by High-definition optical coherence tomography before and after incubation. Real-time 3-D HD-OCT assessment was compared with 2-D en face assessment by reflectance confocal microscopy (RCM). (Immuno) histopathology was used as control. HD-OCT imaging allowed real-time 3-D visualization of the impact of selected agents on epidermal splitting, dermo-epidermal junction, dermal architecture, vascular spaces and cellularity. RCM has a better resolution (1 μm) than HD-OCT (3 μm), permitting differentiation of different collagen fibres, but HD-OCT imaging has deeper penetration (570 μm) than RCM imaging (200 μm). Dispase II and NaCl treatments were found to be equally efficient in the removal of the epidermis from human split-thickness skin allografts. However, a different epidermal splitting level at the dermo-epidermal junction could be observed and confirmed by immunolabelling of collagen type IV and type VII. Epidermal splitting occurred at the level of the lamina densa with dispase II and above the lamina densa (in the lamina lucida) with NaCl. The 3-D architecture of dermal papillae and dermis was more affected by Dispase II on HD-OCT which corresponded with histopathologic (orcein staining) fragmentation of elastic fibres. With SDS treatment, the epidermal removal was incomplete as remnants of the epidermal basal cell layer remained attached to the basement membrane on the dermis. With Triton X-100 treatment, the epidermis was not removed. In conclusion, HD-OCT imaging permits real-time 3-D visualization of the impact of selected agents on human skin allografts. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. Studies of nonlinear femtosecond pulse propagation in bulk materials

    NASA Astrophysics Data System (ADS)

    Eaton, Hilary Kaye

    2000-10-01

    Femtosecond pulse lasers are finding widespread application in a variety of fields including medical research, optical switching and communications, plasma formation, high harmonic generation, and wavepacket formation and control. As the number of applications for femtosecond pulses increases, so does the need to fully understand the linear and nonlinear processes involved in propagating these pulses through materials under various conditions. Recent advances in pulse measurement techniques, such as frequency-resolved optical gating (FROG), allow measurement of the full electric field of the pulse and have made detailed investigations of short- pulse propagation effects feasible. In this thesis, I present detailed experimental studies of my work involving nonlinear propagation of femtosecond pulses in bulk media. Studies of plane-wave propagation in fused silica extend the SHG form of FROG from a simple pulse diagnostic to a useful method of interrogating the nonlinear response of a material. Studies of nonlinear propagation are also performed in a regime where temporal pulse splitting occurs. Experimental results are compared with a three- dimensional nonlinear Schrödinger equation. This comparison fuels the development of a more complete model for pulse splitting. Experiments are also performed at peak input powers above those at which pulse splitting is observed. At these higher intensities, a broadband continuum is generated. This work presents a detailed study of continuum behavior and power loss as well as the first near-field spatial- spectral measurements of the generated continuum light. Nonlinear plane-wave propagation of short pulses in liquids is also investigated, and a non-instantaneous nonlinearity with a surprisingly short response time of 10 fs is observed in methanol. Experiments in water confirm that this effect in methanol is indeed real. Possible explanations for the observed effect are discussed and several are experimentally rejected. This thesis applies FROG as a powerful tool for science and not just a useful pulse diagnostic technique. Studies of three-dimensional propagation provide an in-depth understanding of the processes involved in femtosecond pulse splitting. In addition, the experimental investigations of continuum generation and pulse propagation in liquids provide new insights into the possible processes involved and should provide a useful comparison for developing theories.

  11. Architectural properties of the neuromuscular compartments in selected forearm skeletal muscles

    PubMed Central

    Liu, An-Tang; Liu, Ben-Li; Lu, Li-Xuan; Chen, Gang; Yu, Da-Zhi; Zhu, Lie; Guo, Rong; Dang, Rui-Shan; Jiang, Hua

    2014-01-01

    The purposes f this study were to (i) explore the possibility of splitting the selected forearm muscles into separate compartments in human subjects; (ii) quantify the architectural properties of each neuromuscular compartment; and (iii) discuss the implication of these properties in split tendon transfer procedures. Twenty upper limbs from 10 fresh human cadavers were used in this study. Ten limbs of five cadavers were used for intramuscular nerve study by modified Sihler's staining technique, which confirmed the neuromuscular compartments. The other 10 limbs were included for architectural analysis of neuromuscular compartments. The architectural features of the compartments including muscle weight, muscle length, fiber length, pennation angle, and sarcomere length were determined. Physiological cross-sectional area and fiber length/muscle length ratio were calculated. Five of the selected forearm muscles were ideal candidates for splitting, including flexor carpi ulnaris, flexor carpi radials, extensor carpi radialis brevis, extensor carpi ulnaris and pronator teres. The humeral head of pronator teres contained the longest fiber length (6.23 ± 0.31 cm), and the radial compartment of extensor carpi ulnaris contained the shortest (2.90 ± 0.28 cm). The ulnar compartment of flexor carpi ulnaris had the largest physiological cross-sectional area (5.17 ± 0.59 cm2), and the ulnar head of pronator teres had the smallest (0.67 ± 0.06 cm2). Fiber length/muscle length ratios of the neuromuscular compartments were relatively low (average 0.27 ± 0.09, range 0.18–0.39) except for the ulnar head of pronator teres, which had the highest one (0.72 ± 0.05). Using modified Sihler's technique, this research demonstrated that each compartment of these selected forearm muscles has its own neurovascular supply after being split along its central tendon. Data of the architectural properties of each neuromuscular compartment provide insight into the ‘design’ of their functional capability. In addition to improving our understanding of muscle anatomy and function, elucidation of forearm neuromuscular compartments architecture may ultimately provide information useful for selection of muscle subdivisions used in tendon transfer. PMID:24836406

  12. An optically passive method that doubles the rate of 2-Ghz timing fiducials

    NASA Astrophysics Data System (ADS)

    Boni, R.; Kendrick, J.; Sorce, C.

    2017-08-01

    Solid-state optical comb-pulse generators provide a convenient and accurate method to include timing fiducials in a streak camera image for time base correction. Commercially available vertical-cavity surface-emitting lasers (VCSEL's) emitting in the visible currently in use can be modulated up to 2 GHz. An optically passive method is presented to interleave a time-delayed path of the 2-GHz comb with itself, producing a 4-GHz comb. This technique can be applied to VCSEL's with higher modulation rates. A fiber-delivered, randomly polarized 2-GHz VCSEL comb is polarization split into s-polarization and p-polarization paths. One path is time delayed relative to the other by twice the 2-GHz rate with +/-1-ps accuracy; the two paths then recombine at the fiber-coupled output. High throughput (>=90%) is achieved by carefully using polarization beam-splitting cubes, a total internal reflection beam-path-steering prism, and antireflection coatings. The glass path-length delay block and turning prism are optically contacted together. The beam polarizer cubes that split and recombine the paths are precision aligned and permanently cemented into place. We expect the palm-sized, inline fiber-coupled, comb-rate-doubling device to maintain its internal alignment indefinitely.

  13. Foil chaff ejection systems for rocket-borne measurement of neutral winds in the mesosphere and lower thermosphere

    NASA Astrophysics Data System (ADS)

    Koizumi, Yoshiko; Shimoyama, Manabu; Oyama, Koh-Ichiro; Murayama, Yasuhiro; Tsuda, Toshitaka; Nakamura, Takuji

    2004-07-01

    The foil chaff technique has been used on microrockets such as "Viper" for a long time to measure neutral winds with high altitude resolution in the mesosphere and lower thermosphere. We have developed two new foil chaff storage and ejection systems for muti-instrumented sounding rockets. The first system uses a spring loaded split cylinder which holds the foil chaff, housed in an outer cylinder. The shaft of the split cylinder is kept in place by a lock plate and a stainless steel wire. The split cylinder is ejected by cutting the wire. The second system is of differential pressure type. The cap of an airtight cylinder has a shaft and a sponge piece for sweeping out the foil chaff. The cylinder is sealed at ground level and at the desired height of release, the cap comes out due to differential pressure and brings out the foil chaff. Both these systems were successfully tested on a Japanese sounding rocket in January 2000, releasing about 20 000 pieces of foil chaff during the rocket's descent. Neutral winds were measured in the height range of 85.5-95.0 km with a height resolution of 300 m.

  14. Nanofat grafting under a split-thickness skin graft for problematic wound management.

    PubMed

    Kemaloğlu, Cemal Alper

    2016-01-01

    Obesity and certain medical disorders make the reconstruction of skin defects challenging. Different kind of procedure can be used for these defect, besides, skin grafting is one of the most common and simplest procedure. Fat grafting and stem cells which are located in the adipose tissue have been commonly used in plastic surgery for regeneration and rejuvenation purposes. To decrease graft failure rate we performed nanofat grafting under an autologous split-thickness skin graft in our patient who had a problematic wound. The case of a 35-year-old female patient with a traumatic skin defect on her left anterior crural region is described herein. After subsequent flap reconstruction, the result was disappointing and the defect size was widened. The defect was treated with combined grafting (nanofat grafting under an autologous split-thickness skin graft). At the 6 months follow-up assessment after combined grafting, the integrity of the skin graft was good with excellent pliability. Combined grafting for problematic wounds seems to be a useful technique for cases requiring reconstruction. The potential existence of stem cells may be responsible for the successful result in our patient.

  15. Dynamic behavior of geometrically complex hybrid composite samples in a Split-Hopkinson Pressure Bar system

    NASA Astrophysics Data System (ADS)

    Pouya, M.; Balasubramaniam, S.; Sharafiev, S.; F-X Wagner, M.

    2018-06-01

    The interfaces between layered materials play an important role for the overall mechanical behavior of hybrid composites, particularly during dynamic loading. Moreover, in complex-shaped composites, interfacial failure is strongly affected by the geometry and size of these contact interfaces. As preliminary work for the design of a novel sample geometry that allows to analyze wave reflection phenomena at the interfaces of such materials, a series of experiments using a Split-Hopkinson Pressure Bar technique was performed on five different sample geometries made of a monomaterial steel. A complementary explicit finite element model of the Split-Hopkinson Pressure Bar system was developed and the same sample geometries were studied numerically. The simulated input, reflected and transmitted elastic wave pulses were analyzed for the different sample geometries and were found to agree well with the experimental results. Additional simulations using different composite layers of steel and aluminum (with the same sample geometries) were performed to investigate the effect of material variation on the propagated wave pulses. The numerical results show that the reflected and transmitted wave pulses systematically depend on the sample geometry, and that elastic wave pulse propagation is affected by the properties of individual material layers.

  16. Dose calculation algorithm of fast fine-heterogeneity correction for heavy charged particle radiotherapy.

    PubMed

    Kanematsu, Nobuyuki

    2011-04-01

    This work addresses computing techniques for dose calculations in treatment planning with proton and ion beams, based on an efficient kernel-convolution method referred to as grid-dose spreading (GDS) and accurate heterogeneity-correction method referred to as Gaussian beam splitting. The original GDS algorithm suffered from distortion of dose distribution for beams tilted with respect to the dose-grid axes. Use of intermediate grids normal to the beam field has solved the beam-tilting distortion. Interplay of arrangement between beams and grids was found as another intrinsic source of artifact. Inclusion of rectangular-kernel convolution in beam transport, to share the beam contribution among the nearest grids in a regulatory manner, has solved the interplay problem. This algorithmic framework was applied to a tilted proton pencil beam and a broad carbon-ion beam. In these cases, while the elementary pencil beams individually split into several tens, the calculation time increased only by several times with the GDS algorithm. The GDS and beam-splitting methods will complementarily enable accurate and efficient dose calculations for radiotherapy with protons and ions. Copyright © 2010 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  17. Structure of the Photo-catalytically Active Surface of SrTiO 3

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Plaza, Manuel; Huang, Xin; Ko, J. Y. Peter

    2016-06-29

    A major goal of energy research is to use visible light to cleave water directly, without an applied voltage, into hydrogen and oxygen. Although SrTiO3 requires ultraviolet light, after four decades, it is still the “gold standard” for the photo-catalytic splitting of water. It is chemically robust and can carry out both hydrogen and oxygen evolution reactions without an applied bias. While ultrahigh vacuum surface science techniques have provided useful insights, we still know relatively little about the structure of these electrodes in contact with electrolytes under operating conditions. Here, we report the surface structure evolution of a n-SrTiO3 electrodemore » during water splitting, before and after “training” with an applied positive bias. Operando high-energy X-ray reflectivity measurements demonstrate that training the electrode irreversibly reorders the surface. Scanning electrochemical microscopy at open circuit correlates this training with a 3-fold increase of the activity toward the photo-induced water splitting. A novel first-principles joint density functional theory simulation, constrained to the X-ray data via a generalized penalty function, identifies an anatase-like structure as the more active, trained surface.« less

  18. Structure of the Photo-catalytically Active Surface of SrTiO 3

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Plaza, Manuel; Huang, Xin; Ko, J. Y. Peter

    2016-06-29

    A major goal of energy research is to use visible light to cleave water directly, without an applied voltage, into hydrogen and oxygen. Although SrTiO 3 requires ultraviolet light, after four decades, it is still the "gold standard" for the photo-catalytic splitting of water. It is chemically robust and can carry out both hydrogen and oxygen evolution reactions without an applied bias. While ultrahigh vacuum surface science techniques have provided useful insights, we still know relatively little about the structure of these electrodes in contact with electrolytes under operating conditions. Here, we report the surface structure evolution of a n-SrTiOmore » 3 electrode during water splitting, before and after "training" with an applied positive bias. Operando high-energy X-ray reflectivity measurements demonstrate that training the electrode irreversibly reorders the surface. Scanning electrochemical microscopy at open circuit correlates this training with a 3-fold increase of the activity toward the photo-induced water splitting. A novel first-principles joint density functional theory simulation, constrained to the X-ray data via a generalized penalty function, identifies an anatase-like structure as the more active, trained surface.« less

  19. Two-wave photon Doppler velocimetry measurements in direct impact Hopkinson pressure bar experiments

    NASA Astrophysics Data System (ADS)

    Lea, Lewis J.; Jardine, Andrew P.

    2015-09-01

    Direct impact Hopkinson pressure bar systems offer many potential advantages over split Hopkinson pressure bars, including access to higher strain rates, higher strains for equivalent striker velocity and system length, lower dispersion and faster achievement of force equilibrium. Currently advantages are gained at a significant cost: the fact that input bar data is unavailable removes all information about the striker impacted specimen face, preventing the determination of force equilibrium, and requiring approximations to be made on the sample deformation history. Recently photon Doppler velocimetry methods have been developed, which can replace strain gauges on Hopkinson bars. In this paper we discuss an experimental method and complementary data analysis for using Doppler velocimetry to measure surface velocities of the striker and output bars in a direct impact bar experiment, allowing similar data to be recorded as in a split bar system, with the same level of convenience. We discuss extracting velocity and force measurements, and improving the accuracy and convenience of Doppler velocimetry on Hopkinson bars. Results obtained using the technique are compared to equivalent split bar tests, showing improved stress measurements for the lowest and highest strains.

  20. Hyperfine rather than spin splittings dominate the fine structure of the B (4)Σ(-)-X (4)Σ(-) bands of AlC.

    PubMed

    Clouthier, Dennis J; Kalume, Aimable

    2016-01-21

    Laser-induced fluorescence and wavelength resolved emission spectra of the B (4)Σ(-)-X (4)Σ(-) band system of the gas phase cold aluminum carbide free radical have been obtained using the pulsed discharge jet technique. The radical was produced by electron bombardment of a precursor mixture of trimethylaluminum in high pressure argon. High resolution spectra show that each rotational line of the 0-0 and 1-1 bands of AlC is split into at least three components, with very similar splittings and intensities in both the P- and R-branches. The observed structure was reproduced by assuming bβS magnetic hyperfine coupling in the excited state, due to a substantial Fermi contact interaction of the unpaired electron in the aluminum 3s orbital. Rotational analysis has yielded ground and excited state equilibrium bond lengths in good agreement with the literature and our own ab initio values. Small discrepancies in the calculated intensities of the hyperfine lines suggest that the upper state spin-spin constant λ' is of the order of ≈ 0.025-0.030 cm(-1).

  1. Rotational Splittings of Acoustic Modes in an Experimental Model of a Planetary Core

    NASA Astrophysics Data System (ADS)

    Adams, M. M.; Stone, D.; Lathrop, D. P.

    2014-12-01

    Planetary zonal flows can be probed in principle using the tools of helioseismology. We explore this technique using laboratory experiments where the measurement of zonal flows is also of geophysical relevance. The experiments are carried out in a device with a geometry similar to that of Earth's core. It consists of a 60 cm diameter outer spherical shell concentric with a 20 cm diameter inner sphere. Air between the inner sphere and outer shell is used as the working fluid. A turbulent shear flow is driven in the air by independently rotating the inner sphere and outer shell. Acoustic modes are excited in the vessel with a speaker, and microphones are used to measure the rotational splittings of these modes. The radial profile of azimuthal velocities is inferred from these splittings, in an approach analogous to that used in helioseismology to determine solar velocity profiles. By varying the inner and outer rotation rates, different turbulent states can be investigated. Comparison is made to previous experimental investigations of turbulent spherical Couette flow. These experiments also serve as a test of this diagnostic, which may be used in the future in liquid sodium experiments, providing information on zonal flows in hydromagnetic experiments.

  2. Fast, accurate photon beam accelerator modeling using BEAMnrc: A systematic investigation of efficiency enhancing methods and cross-section data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fragoso, Margarida; Kawrakow, Iwan; Faddegon, Bruce A.

    In this work, an investigation of efficiency enhancing methods and cross-section data in the BEAMnrc Monte Carlo (MC) code system is presented. Additionally, BEAMnrc was compared with VMC++, another special-purpose MC code system that has recently been enhanced for the simulation of the entire treatment head. BEAMnrc and VMC++ were used to simulate a 6 MV photon beam from a Siemens Primus linear accelerator (linac) and phase space (PHSP) files were generated at 100 cm source-to-surface distance for the 10x10 and 40x40 cm{sup 2} field sizes. The BEAMnrc parameters/techniques under investigation were grouped by (i) photon and bremsstrahlung cross sections,more » (ii) approximate efficiency improving techniques (AEITs), (iii) variance reduction techniques (VRTs), and (iv) a VRT (bremsstrahlung photon splitting) in combination with an AEIT (charged particle range rejection). The BEAMnrc PHSP file obtained without the efficiency enhancing techniques under study or, when not possible, with their default values (e.g., EXACT algorithm for the boundary crossing algorithm) and with the default cross-section data (PEGS4 and Bethe-Heitler) was used as the ''base line'' for accuracy verification of the PHSP files generated from the different groups described previously. Subsequently, a selection of the PHSP files was used as input for DOSXYZnrc-based water phantom dose calculations, which were verified against measurements. The performance of the different VRTs and AEITs available in BEAMnrc and of VMC++ was specified by the relative efficiency, i.e., by the efficiency of the MC simulation relative to that of the BEAMnrc base-line calculation. The highest relative efficiencies were {approx}935 ({approx}111 min on a single 2.6 GHz processor) and {approx}200 ({approx}45 min on a single processor) for the 10x10 field size with 50 million histories and 40x40 cm{sup 2} field size with 100 million histories, respectively, using the VRT directional bremsstrahlung splitting (DBS) with no electron splitting. When DBS was used with electron splitting and combined with augmented charged particle range rejection, a technique recently introduced in BEAMnrc, relative efficiencies were {approx}420 ({approx}253 min on a single processor) and {approx}175 ({approx}58 min on a single processor) for the 10x10 and 40x40 cm{sup 2} field sizes, respectively. Calculations of the Siemens Primus treatment head with VMC++ produced relative efficiencies of {approx}1400 ({approx}6 min on a single processor) and {approx}60 ({approx}4 min on a single processor) for the 10x10 and 40x40 cm{sup 2} field sizes, respectively. BEAMnrc PHSP calculations with DBS alone or DBS in combination with charged particle range rejection were more efficient than the other efficiency enhancing techniques used. Using VMC++, accurate simulations of the entire linac treatment head were performed within minutes on a single processor. Noteworthy differences ({+-}1%-3%) in the mean energy, planar fluence, and angular and spectral distributions were observed with the NIST bremsstrahlung cross sections compared with those of Bethe-Heitler (BEAMnrc default bremsstrahlung cross section). However, MC calculated dose distributions in water phantoms (using combinations of VRTs/AEITs and cross-section data) agreed within 2% of measurements. Furthermore, MC calculated dose distributions in a simulated water/air/water phantom, using NIST cross sections, were within 2% agreement with the BEAMnrc Bethe-Heitler default case.« less

  3. [The usage of inferior turbinate mucosal flap for repairing cleft lip].

    PubMed

    Gao, Pu; Zhao, Min; Qi, Ke-ming; Zhao, Zhen-min; Xiong, Bin

    2004-05-01

    To evaluate a technique for decreasing the tension of the nasal floor during the procedures of repairing complete clef lip. With the designation of an inferior turbinate mucosal flap combined with an oral mucosal flap in the splitting side, the tension was effectively decreased and the nasal floor was closed easily. Eighteen patients was selected for the treatment with this technique since 2000. The follow-ups were 10 to 24 months. All of the patients showed wound healing well with the significant improvement in the donor site. The above mentioned technique may effectively decrease the tension and be used to close the nasal floor safely. It could also reduce the incidence of the complications.

  4. Improved ITOS attitude control system with Hall generator brushless motor and earth-splitting technique

    NASA Technical Reports Server (NTRS)

    Peacock, W. M.

    1971-01-01

    The ITOS with an improved attitude control system is described. A Hall generator brushless dc torque motor will replace the brush dc torque motor on ITOS-I and ITOS-A (NOAA-1). The four attitude horizon sensors will be replaced with two CO2 sensors for better horizon definition. An earth horizon splitting technique will be used to keep the earth facing side of the satellite toward earth even if the desired circular orbit is not achieved. The external appearance of the pitch control subsystem differs from TIROS-M (ITOS-1) and ITOS-A (NOAA-1) in that two instead of one pitch control electronics (PCE) boxes are used. Two instead of four horizon sensors will be used and one instead of two mirrors will be used for sensor scanning. The brushless motor will eliminate the requirement for brushes, strain gages and the telemetry for the brush wear. A single rotating flywheel, supported by a single bearing provides the gyroscopic stability and the required momentum interchange to keep one side of the satellite facing the earth. Magnetic torquing against the earth's magnetic field eliminates the requirement for expendable propellants which would limit satellite life in orbit.

  5. Status of research and development on photoelectrochemical hydrogen production in Korea

    NASA Astrophysics Data System (ADS)

    Kim, Jong Won; Lee, Jae S.; Baeg, Jin-Ook

    2010-08-01

    Conversion of solar energy into hydrogen is one of the most promising renewable energy technologies. Photocatalytic production of hydrogen from water, H2S and organic wastes using semiconductors is one of the potential strategies for converting the sunlight energy into chemical energy. Korea government paid great attention to the hydrogen economy and launched the HERC (Hydrogen Energy R&D Center) for supporting the R&D topics on hydrogen related technologies. The key issue for realizing the commercial application of solar water splitting hydrogen production technique is to find an efficient, stable and low-cost photocatalyst. Our research groups have continuously investigated to find oxide and composite photocatalysts for photoelectrochemical cell with high efficiency using computational design and synthesis method. But, fundamental research on semiconductor doping for band gap shifting and surface chemistry modification is still required. Various reaction media containing sacrificial agents should be developed to match with high activity photocatalysts to further improve the system efficiency. Water containing organic/inorganic waste and sea water are particularly suggested in the consideration that all these water sources are the most available water on the earth to the final commercial application of photocatalytic water splitting technique.

  6. [The appraisal of reliability and validity of subjective workload assessment technique and NASA-task load index].

    PubMed

    Xiao, Yuan-mei; Wang, Zhi-ming; Wang, Mian-zhen; Lan, Ya-jia

    2005-06-01

    To test the reliability and validity of two mental workload assessment scales, i.e. subjective workload assessment technique (SWAT) and NASA task load index (NASA-TLX). One thousand two hundred and sixty-eight mental workers were sampled from various kinds of occupations, such as scientific research, education, administration and medicine, etc, with randomized cluster sampling. The re-test reliability, split-half reliability, Cronbach's alpha coefficient and correlation coefficients between item score and total score were adopted to test the reliability. The test of validity included structure validity. The re-test reliability coefficients of these two scales and their items were ranged from 0.516 to 0.753 (P < 0.01), indicating the two scales had good re-test reliability; the split-half reliability of SWAT was 0.645, and its Cronbach's alpha coefficient was more than 0.80, all the correlation coefficients between its items score and total score were more than 0.70; as for NASA-TLX, both the split-half reliability and Cronbach's alpha coefficient were more than 0.80, the correlation coefficients between its items score and total score were all more than 0.60 (P < 0.01) except the item of performance. Both scales had good inner consistency. The Pearson correlation coefficient between the two scales was 0.492 (P < 0.01), implying the results of the two scales had good consistency. Factor analysis showed that the two scales had good structure validity. Both SWAT and NASA-TLX have good reliability and validity and may be used as a valid tool to assess mental workload in China after being revised properly.

  7. Split Hopkinson resonant bar test for sonic-frequency acoustic velocity and attenuation measurements of small, isotropic geological samples.

    PubMed

    Nakagawa, Seiji

    2011-04-01

    Mechanical properties (seismic velocities and attenuation) of geological materials are often frequency dependent, which necessitates measurements of the properties at frequencies relevant to a problem at hand. Conventional acoustic resonant bar tests allow measuring seismic properties of rocks and sediments at sonic frequencies (several kilohertz) that are close to the frequencies employed for geophysical exploration of oil and gas resources. However, the tests require a long, slender sample, which is often difficult to obtain from the deep subsurface or from weak and fractured geological formations. In this paper, an alternative measurement technique to conventional resonant bar tests is presented. This technique uses only a small, jacketed rock or sediment core sample mediating a pair of long, metal extension bars with attached seismic source and receiver-the same geometry as the split Hopkinson pressure bar test for large-strain, dynamic impact experiments. Because of the length and mass added to the sample, the resonance frequency of the entire system can be lowered significantly, compared to the sample alone. The experiment can be conducted under elevated confining pressures up to tens of MPa and temperatures above 100 [ordinal indicator, masculine]C, and concurrently with x-ray CT imaging. The described split Hopkinson resonant bar test is applied in two steps. First, extension and torsion-mode resonance frequencies and attenuation of the entire system are measured. Next, numerical inversions for the complex Young's and shear moduli of the sample are performed. One particularly important step is the correction of the inverted Young's moduli for the effect of sample-rod interfaces. Examples of the application are given for homogeneous, isotropic polymer samples, and a natural rock sample. © 2011 American Institute of Physics

  8. An ICSI rate of 90% minimizes complete failed fertilization and provides satisfactory implantation rates without elevating fetal abnormalities.

    PubMed

    Yovich, John L; Conceicao, Jason L; Marjanovich, Nicole; Ye, Yun; Hinchliffe, Peter M; Dhaliwal, Satvinder S; Keane, Kevin N

    2018-05-22

    IVF cycles utilizing the ICSI technique for fertilization have been rising over the 25 years since its introduction, with indications now extending beyond male factor infertility. We have performed ICSI for 87% of cases compared with the ANZARD average of 67%. This retrospective study reports on the outcomes of 1547 autologous ART treatments undertaken over a recent 3-year period. Based on various indications, cases were managed within 3 groupings - IVF Only, ICSI Only or IVF-ICSI Split insemination where oocytes were randomly allocated. Overall 567 pregnancies arose from mostly single embryo transfer procedures up to December 2016, with 402 live births, comprising 415 infants and a low fetal abnormality rate (1.9%) was recorded. When the data was adjusted for confounders such as maternal age, measures of ovarian reserve and sperm quality, it appeared that IVF-generated and ICSI-generated embryos had a similar chance of both pregnancy and live birth. In the IVF-ICSI Split model, significantly more ICSI-generated embryos were utilised (2.5 vs 1.8; p < 0.003) with productivity rates of 67.8% for pregnancy and 43.4% for livebirths per OPU for this group. We conclude that ART clinics should apply the insemination method which will maximize embryo numbers and the first treatment for unexplained infertility should be undertaken within the IVF-ICSI Split model. Whilst ICSI-generated pregnancies are reported to have a higher rate of fetal abnormalities, our data is consistent with the view that the finding is not due to the ICSI technique per se. Copyright © 2018 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn. Published by Elsevier B.V. All rights reserved.

  9. A New Method of Assessing Uncertainty of the Cross-Convolution Method of Shear Wave Splitting Measurement

    NASA Astrophysics Data System (ADS)

    Schutt, D.; Breidt, J.; Corbalan Castejon, A.; Witt, D. R.

    2017-12-01

    Shear wave splitting is a commonly used and powerful method for constraining such phenomena as lithospheric strain history or asthenospheric flow. However, a number of challenges with the statistics of shear wave splitting have been noted. This creates difficulties in assessing whether two separate measurements are statistically similar or are indicating real differences in anisotropic structure, as well as for created proper station averaged sets of parameters for more complex situations such as multiple or dipping layers of anisotropy. We present a new method for calculating the most likely splitting parameters using the Menke and Levin [2003] method of cross-convolution. The Menke and Levin method is used because it can more readily be applied to a wider range of anisotropic scenarios than the commonly used Silver and Chan [1991] technique. In our approach, we derive a formula for the spectral density of a function of the microseismic noise and the impulse response of the correct anisotropic model that holds for the true anisotropic model parameters. This is compared to the spectral density of the observed signal convolved with the impulse response for an estimated set of anisotropic parameters. The most likely parameters are found when the former and latter spectral densities are the same. By using the Whittle likelihood to compare the two spectral densities, a likelihood grid for all possible anisotropic parameter values is generated. Using bootstrapping, the uncertainty and covariance between the various anisotropic parameters can be evaluated. We will show this works with a single layer of anisotropy and a vertically incident ray, and discuss the usefulness for a more complex case. The method shows great promise for calculating multiple layer anisotropy parameters with proper assessment of uncertainty. References: Menke, W., and Levin, V. 2003. The cross-convolution method for interpreting SKS splitting observations, with application to one and two-layer anisotropic earth models. Geophysical Journal International, 154: 379-392. doi:10.1046/j.1365-246X.2003.01937.x. Silver, P.G., and Chan, W.W. 1991. Shear Wave Splitting and Sub continental Mantle Deformation. Journal of Geophysical Research, 96: 429-454. doi:10.1029/91JB00899.

  10. To split or not to split: colostomy complications for anorectal malformations or hirschsprung disease: a single center experience and a systematic review of the literature.

    PubMed

    van den Hondel, Desiree; Sloots, Cornelius; Meeussen, Conny; Wijnen, Rene

    2014-02-01

    The aim of this article is to identify the ideal type and location of colostomy in children with colorectal disease. A retrospective case study of children with an anorectal malformation who received a colostomy, born between January 1990 and July 2012. Furthermore, a systematic literature search on colostomies in neonates with an anorectal malformation or Hirschsprung disease. Colostomies were classified as loop or split colostomies in the transverse or sigmoid colon. Outcome measures were mortality and complications such as prolapse, technical difficulties with the reconstruction, urinary tract infections, and others. The mortality rate in the 180 children with anorectal malformation was 6%, and none of them were directly related to stoma formation or closure. The overall complication rate was 23% and the specific rates for the two types of procedures and the two locations of the colostomy did not differ (p = 0.389 and p = 0.667, respectively). All prolapses (n = 22) occurred in loop colostomies in the transverse colon. One colostomy required revision because of insufficient length for the reconstruction. Urinary tract infections were not documented. A total of eight studies were included in the systematic review (1982-2011; 2,954 patients). Mortality ranged between 0.1 and 11%. Loop colostomies had more complications than split colostomies (63 vs. 45%; p = 0.007), mainly prolapse (18 vs. 6%; p < 0.001). Overall complication rate differed between transverse en sigmoid colostomies (62 vs. 51%, p = 0.006), and prolapse occurred more often in the transverse colon (23 vs. 7%; p < 0.001). Revision because of insufficient length during the reconstruction was needed in 0 to 6%. Two studies reported on urinary tract infections which are as follows: One showed no difference between loop or split colostomies, whereas the other showed frequent episodes of urinary tract infections in 64% of the loop colostomies. The complication to be avoided in transverse colostomies is prolapse and the surgical technique should be modified accordingly. The procedure of split sigmoid colostomy is meticulous, and the risk of insufficient length for the reconstruction remains. Georg Thieme Verlag KG Stuttgart · New York.

  11. Dynamic Deformation Behavior of Soft Material Using Shpb Technique and Pulse Shaper

    NASA Astrophysics Data System (ADS)

    Lee, Ouk Sub; Cho, Kyu Sang; Kim, Sung Hyun; Han, Yong Hwan

    This paper presents a modified Split Hopkinson Pressure Bar (SHPB) technique to obtain compressive stress strain data for NBR rubber materials. An experimental technique with a modified the conventional SHPB has been developed for measuring the compressive stress strain responses of materials with low mechanical impedance and low compressive strengths, such as the rubber and the polymeric material. This paper uses an aluminum pressure bar to achieve a closer impedance match between the pressure bar and the specimen materials. In addition, a pulse shaper is utilized to lengthen the rising time of the incident pulse to ensure dynamic stress equilibrium and homogeneous deformation of NBR rubber materials. It is found that the modified technique can determine the dynamic deformation behavior of rubbers more accurately.

  12. Double-side illuminated titania nanotubes for high volume hydrogen generation by water splitting

    NASA Astrophysics Data System (ADS)

    Mohapatra, Susanta K.; Mahajan, Vishal K.; Misra, Mano

    2007-11-01

    A sonoelectrochemical anodization method is proposed to synthesize TiO2 nanotubular arrays on both sides of a titanium foil (TiO2/Ti/TiO2). Highly ordered TiO2 nanotubular arrays of 16 cm2 area with uniform surface distribution can be obtained using this anodization procedure. These double-sided TiO2/Ti/TiO2 materials are used as both photoanode (carbon-doped titania nanotubes) and cathode (Pt nanoparticles dispersed on TiO2 nanotubes; PtTiO2/Ti/PtTiO2) in a specially designed photoelectrochemical cell to generate hydrogen by water splitting at a rate of 38 ml h-1. The nanomaterials are characterized by FESEM, HRTEM, STEM, EDS, FFT, SAED and XPS techniques. The present approach can be used for large-scale hydrogen generation using renewable energy sources.

  13. Improving Transportation Services for the University of the Thai Chamber of Commerce: A Case Study on Solving the Mixed-Fleet Vehicle Routing Problem with Split Deliveries

    NASA Astrophysics Data System (ADS)

    Suthikarnnarunai, N.; Olinick, E.

    2009-01-01

    We present a case study on the application of techniques for solving the Vehicle Routing Problem (VRP) to improve the transportation service provided by the University of The Thai Chamber of Commerce to its staff. The problem is modeled as VRP with time windows, split deliveries, and a mixed fleet. An exact algorithm and a heuristic solution procedure are developed to solve the problem and implemented in the AMPL modeling language and CPLEX Integer Programming solver. Empirical results indicate that the heuristic can find relatively good solutions in a small fraction of the time required by the exact method. We also perform sensitivity analysis and find that a savings in outsourcing cost can be achieved with a small increase in vehicle capacity.

  14. The EPR study of Mn(2+) ion doped DADT single crystal produced under high pressure and temperature.

    PubMed

    Ceylan, Ümit; Tapramaz, Recep

    2016-01-05

    An EPR study on Cu(2+) and VO(2+) doped di ammonium d-tartrate single crystals has been reported in previous papers, but the same host did not accept Mn(2+) ion at the same reaction conditions in previous trials. In this study EPR study of Mn(2+) ion doped di ammonium d tartrate single crystal, (DADT) [(NH4)2C4H4O6], produced in a reactor under high pressure and high temperature. The electronic transitions were determined by the optical absorption spectrum. Hyperfine splitting and g values of the Mn(2+) ion forming a complex in the lattice were measured from experimental spectra and spin-spin dipolar splitting parameters D and E were found by the spectrum simulation techniques. Copyright © 2015 Elsevier B.V. All rights reserved.

  15. Nanostructured hematite thin films for photoelectrochemical water splitting

    NASA Astrophysics Data System (ADS)

    Maabong, Kelebogile; Machatine, Augusto G. J.; Mwankemwa, Benard S.; Braun, Artur; Bora, Debajeet K.; Toth, Rita; Diale, Mmantsae

    2018-04-01

    Nanostructured hematite thin films prepared by dip coating technique were investigated for their photoelectrochemical activity for generation of hydrogen from water splitting. Structural, morphological and optical analyses of the doped/undoped films were performed by X-ray diffraction, high resolution field emission-scanning electron microscopy, UV-vis spectrophotometry and Raman spectroscopy. The photoelectrochemical measurements of the films showed enhanced photoresponse and cathodic shift of the onset potential upon Ti doping indicating improved transfer of photoholes at the semiconductor-electrolyte interface. Films doped with 1 at% Ti produced 0.72 mA/cm2 at 1.23 V vs RHE which is 2 times higher than current density for the pure film (0.30 mA/cm2, at 1.23 V vs RHE). Gas chromatography analysis of the films also showed enhanced hydrogen evolution at 1 at% Ti with respect to pure film.

  16. Surface Plasmon Enhanced Sensitive Detection for Possible Signature of Majorana Fermions via a Hybrid Semiconductor Quantum Dot-Metal Nanoparticle System

    PubMed Central

    Chen, Hua-Jun; Zhu, Ka-Di

    2015-01-01

    In the present work, we theoretically propose an optical scheme to detect the possible signature of Majorana fermions via the optical pump-probe spectroscopy, which is very different from the current tunneling measurement based on electrical methods. The scheme consists of a metal nanoparticle and a semiconductor quantum dot coupled to a hybrid semiconductor/superconductor heterostructures. The results show that the probe absorption spectrum of the quantum dot presents a distinct splitting due to the existence of Majorana fermions. Owing to surface plasmon enhanced effect, this splitting will be more obvious, which makes Majorana fermions more easy to be detectable. The technique proposed here open the door for new applications ranging from robust manipulation of Majorana fermions to quantum information processing based on Majorana fermions. PMID:26310929

  17. Mass sensor based on split-nanobeam optomechanical oscillator

    NASA Astrophysics Data System (ADS)

    Zhang, Yeping; Ai, Jie; Xiang, Yanjun; He, Qinghua; Li, Tao; Ma, Jingfang

    2016-03-01

    Mass sensing based on monitoring the frequency shifts induced by added mass in oscillators is a well-known and widely used technique. The optomechanical crystal cavity has strong interaction between optical mode and mechanical mode. Radiation pressure driven optomechanical crystal cavity are excellent candidates for mass detection due to their simplicity, sensitivity and all optical operation. In an optomechanical crystal cavity, a high quality factor optical mode simultaneously serves as an efficient actuator and a sensitive probe for precise monitoring the mechanical frequency change of the cavity structure. Here, a split-nanobeam optomechanical crystal cavity is proposed, the sensing resolution as small as 0.33ag (1ag=10-21kg) and the frequency shift is more than 30MHz. This is important and promising for achieve ultimate-precision mass sensing including proteins and other molecules.

  18. The visible touch: in planta visualization of protein-protein interactions by fluorophore-based methods

    PubMed Central

    Bhat, Riyaz A; Lahaye, Thomas; Panstruga, Ralph

    2006-01-01

    Non-invasive fluorophore-based protein interaction assays like fluorescence resonance energy transfer (FRET) and bimolecular fluorescence complementation (BiFC, also referred to as "split YFP") have been proven invaluable tools to study protein-protein interactions in living cells. Both methods are now frequently used in the plant sciences and are likely to develop into standard techniques for the identification, verification and in-depth analysis of polypeptide interactions. In this review, we address the individual strengths and weaknesses of both approaches and provide an outlook about new directions and possible future developments for both techniques. PMID:16800872

  19. A new traffic control design method for large networks with signalized intersections

    NASA Technical Reports Server (NTRS)

    Leininger, G. G.; Colony, D. C.; Seldner, K.

    1979-01-01

    The paper presents a traffic control design technique for application to large traffic networks with signalized intersections. It is shown that the design method adopts a macroscopic viewpoint to establish a new traffic modelling procedure in which vehicle platoons are subdivided into main stream queues and turning queues. Optimization of the signal splits minimizes queue lengths in the steady state condition and improves traffic flow conditions, from the viewpoint of the traveling public. Finally, an application of the design method to a traffic network with thirty-three signalized intersections is used to demonstrate the effectiveness of the proposed technique.

  20. Model-size reduction for the buckling and vibration analyses of anisotropic panels

    NASA Technical Reports Server (NTRS)

    Noor, A. K.; Whitworth, S. L.

    1986-01-01

    A computational procedure is presented for reducing the size of the model used in the buckling and vibration analyses of symmetric anisotropic panels to that of the corresponding orthotropic model. The key elements of the procedure are the application of an operator splitting technique through the decomposition of the material stiffness matrix of the panel into the sum of orthotropic and nonorthotropic (anisotropic) parts and the use of a reduction method through successive application of the finite element method and the classical Rayleigh-Ritz technique. The effectiveness of the procedure is demonstrated by numerical examples.

  1. Comparative studies on different nanofiber photocatalysts for water splitting

    NASA Astrophysics Data System (ADS)

    Alharbi, Abdulaziz; Alarifi, Ibrahim M.; Khan, Waseem S.; Asmatulu, Ramazan

    2016-04-01

    Water splitting using photocatalyst has become a topic of recent investigation since it has the potential of producing hydrogen for clean energy from sunlight. An extensive number of solid photocatalysts have been studied for overall water splitting in recent years. In this study, two methods were employed to synthesize two different photocatalysts for water splitting. The first method describes the synthesis of nickel oxide-loaded strontium titanate (NiO-SrTiO3) particles on electrospun polyacrylonitrile (PAN) nanofibers incorporated with graphene nanoplatelets for water splitting. The electrospun PAN fibers were first oxidized at 270°C for two hours and subsequently immersed in a solution containing ethanol, titanium (IV)-isopropoxide [C12H28O4Ti] and strontium nitrate [Sr(NO3)2]. This solution was then treated with NiO nanoparticles dispersed in toluene. The surface treated PAN fibers were annealed at 600°C in air for 1 hour to transform fibers into a crystalline form for improved photocatalyst performance. In the second method, coaxial electrospinning process was used to produce core/shell strontium titanate/nickel oxide (SrTiO3-NiO) nanofibers. In coaxial method, poly (vinyl pyrrolidone) (PVP) was dissolved in deionized (DI) water, and then titanium (IV) isopropoxide [C12H28O4Ti] and strontium nitrate [Sr(NO3)2] were added into the solution to form the inner (core) layer. For outer (shell) solution, polyacrylonitrile (PAN) polymer was dissolved in dimethylformamide (DMF) at a weight ratio of 10:90 and then nickel oxide was mixed with the solution. Ultraviolet (UV) spectrophotometry and static contact angle measurement techniques were employed to characterize the structural properties of photocatalysts produced by both methods and a comparison was made between the two photocatalysts. The morphology and diameter of the nanofibers were observed by scanning electron microscopy (SEM). The structure and crystallinity of the calcined nanofibers were also observed by means of X-ray diffraction (XRD).

  2. Investigating the Consistency of Models for Water Splitting Systems by Light and Voltage Modulated Techniques.

    PubMed

    Bertoluzzi, Luca; Bisquert, Juan

    2017-01-05

    The optimization of solar energy conversion devices relies on their accurate and nondestructive characterization. The small voltage perturbation techniques of impedance spectroscopy (IS) have proven to be very powerful to identify the main charge storage modes and charge transfer processes that control device operation. Here we establish the general connection between IS and light modulated techniques such as intensity modulated photocurrent (IMPS) and photovoltage spectroscopies (IMVS) for a general system that converts light to energy. We subsequently show how these techniques are related to the steady-state photocurrent and photovoltage and the external quantum efficiency. Finally, we express the IMPS and IMVS transfer functions in terms of the capacitive and resistive features of a general equivalent circuit of IS for the case of a photoanode used for solar fuel production. We critically discuss how much knowledge can be extracted from the combined use of those three techniques.

  3. Two-boundary grid generation for the solution of the three dimensional compressible Navier-Stokes equations. Ph.D. Thesis - Old Dominion Univ.

    NASA Technical Reports Server (NTRS)

    Smith, R. E.

    1981-01-01

    A grid generation technique called the two boundary technique is developed and applied for the solution of the three dimensional Navier-Stokes equations. The Navier-Stokes equations are transformed from a cartesian coordinate system to a computational coordinate system, and the grid generation technique provides the Jacobian matrix describing the transformation. The two boundary technique is based on algebraically defining two distinct boundaries of a flow domain and the distribution of the grid is achieved by applying functions to the uniform computational grid which redistribute the computational independent variables and consequently concentrate or disperse the grid points in the physical domain. The Navier-Stokes equations are solved using a MacCormack time-split technique. Grids and supersonic laminar flow solutions are obtained for a family of three dimensional corners and two spike-nosed bodies.

  4. Fluid control structures in microfluidic devices

    DOEpatents

    Mathies, Richard A.; Grover, William H.; Skelley, Alison; Lagally, Eric; Liu, Chung N.

    2008-11-04

    Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and actuation of a variety of fluid control structures, such as structures for pumping, isolating, mixing, routing, merging, splitting, preparing, and storing volumes of fluid. The fluid control structures can be used to implement a variety of sample introduction, preparation, processing, and storage techniques.

  5. Fluid control structures in microfluidic devices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mathies, Richard A.; Grover, William H.; Skelley, Alison

    2017-05-09

    Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and actuation of a variety of fluid control structures, such as structures for pumping, isolating, mixing, routing, merging, splitting, preparing, and storing volumes of fluid. The fluid control structures can be used to implement a variety of sample introduction, preparation, processing, and storage techniques.

  6. Tooling Converts Stock Bearings To Custom Bearings

    NASA Technical Reports Server (NTRS)

    Fleenor, E. N., Jr.

    1983-01-01

    Technique for reworking stock bearings saves time and produces helicopter-rotor bearings ground more precisely. Split tapered ring at one end of threaded bolt expands to hold inside of inner race bearing assembly; nut, at other end of bolt, adjusts amount of spring tension. Piece of hardware grasps bearing firmly without interfering with grinding operation. Operation produces bearing of higher quality than commercially available bearings.

  7. Fluid control structures in microfluidic devices

    NASA Technical Reports Server (NTRS)

    Skelley, Alison (Inventor); Mathies, Richard A. (Inventor); Lagally, Eric (Inventor); Grover, William H. (Inventor); Liu, Chung N. (Inventor)

    2008-01-01

    Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and actuation of a variety of fluid control structures, such as structures for pumping, isolating, mixing, routing, merging, splitting, preparing, and storing volumes of fluid. The fluid control structures can be used to implement a variety of sample introduction, preparation, processing, and storage techniques.

  8. The Advantages of Collimator Optimization for Intensity Modulated Radiation Therapy

    NASA Astrophysics Data System (ADS)

    Doozan, Brian

    The goal of this study was to improve dosimetry for pelvic, lung, head and neck, and other cancers sites with aspherical planning target volumes (PTV) using a new algorithm for collimator optimization for intensity modulated radiation therapy (IMRT) that minimizes the x-jaw gap (CAX) and the area of the jaws (CAA) for each treatment field. A retroactive study on the effects of collimator optimization of 20 patients was performed by comparing metric results for new collimator optimization techniques in Eclipse version 11.0. Keeping all other parameters equal, multiple plans are created using four collimator techniques: CA 0, all fields have collimators set to 0°, CAE, using the Eclipse collimator optimization, CAA, minimizing the area of the jaws around the PTV, and CAX, minimizing the x-jaw gap. The minimum area and the minimum x-jaw angles are found by evaluating each field beam's eye view of the PTV with ImageJ and finding the desired parameters with a custom script. The evaluation of the plans included the monitor units (MU), the maximum dose of the plan, the maximum dose to organs at risk (OAR), the conformity index (CI) and the number of fields that are calculated to split. Compared to the CA0 plans, the monitor units decreased on average by 6% for the CAX method with a p-value of 0.01 from an ANOVA test. The average maximum dose remained within 1.1% difference between all four methods with the lowest given by CAX. The maximum dose to the most at risk organ was best spared by the CAA method, which decreased by 0.62% compared to the CA0. Minimizing the x-jaws significantly reduced the number of split fields from 61 to 37. In every metric tested the CAX optimization produced comparable or superior results compared to the other three techniques. For aspherical PTVs, CAX on average reduced the number of split fields, lowered the maximum dose, minimized the dose to the surrounding OAR, and decreased the monitor units. This is achieved while maintaining the same control of the PTV.

  9. Split-spectrum processing technique for SNR enhancement of ultrasonic guided wave.

    PubMed

    Pedram, Seyed Kamran; Fateri, Sina; Gan, Lu; Haig, Alex; Thornicroft, Keith

    2018-02-01

    Ultrasonic guided wave (UGW) systems are broadly used in several branches of industry where the structural integrity is of concern. In those systems, signal interpretation can often be challenging due to the multi-modal and dispersive propagation of UGWs. This results in degradation of the signals in terms of signal-to-noise ratio (SNR) and spatial resolution. This paper employs the split-spectrum processing (SSP) technique in order to enhance the SNR and spatial resolution of UGW signals using the optimized filter bank parameters in real time scenario for pipe inspection. SSP technique has already been developed for other applications such as conventional ultrasonic testing for SNR enhancement. In this work, an investigation is provided to clarify the sensitivity of SSP performance to the filter bank parameter values for UGWs such as processing bandwidth, filter bandwidth, filter separation and a number of filters. As a result, the optimum values are estimated to significantly improve the SNR and spatial resolution of UGWs. The proposed method is synthetically and experimentally compared with conventional approaches employing different SSP recombination algorithms. The Polarity Thresholding (PT) and PT with Minimization (PTM) algorithms were found to be the best recombination algorithms. They substantially improved the SNR up to 36.9dB and 38.9dB respectively. The outcome of the work presented in this paper paves the way to enhance the reliability of UGW inspections. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Design constraints of the LST fine guidance sensor

    NASA Technical Reports Server (NTRS)

    Wissinger, A. B.

    1975-01-01

    The LST Fine Guidance Sensor design is shaped by the rate of occurrence of suitable guide stars, the competition for telescope focal plane space with the Science Instruments, and the sensitivity of candidate image motion sensors. The relationship between these parameters is presented, and sensitivity to faint stars is shown to be of prime importance. An interferometric technique of image motion sensing is shown to have improved sensitivity and, therefore, a reduced focal plane area requirement in comparison with other candidate techniques (image-splitting prism and image dissector tube techniques). Another design requirement is speed in acquiring the guide star in order to maximize the time available for science observations. The design constraints are shown parametrically, and modelling results are presented.

  11. The Double Edge Technique for Doppler lidar wind measurement

    NASA Technical Reports Server (NTRS)

    Korb, C. Laurence; Gentry, Bruce M.; Li, S. Xingfu; Flesia, Cristina; Chen, Huailin; Mathur, S.

    1998-01-01

    The edge technique utilizes the edge of a high spectral resolution filter for high accuracy wind measurement using direct detection lidar. The signal is split between an edge filter channel and a broadband energy monitor channel. The energy monitor channel is used for signal normalization. The edge measurement is made as a differential frequency measurement between the outgoing laser signal and the atmospheric backscattered return for each pulse. As a result, the measurement is insensitive to laser and edge filter frequency jitter and drift at a level less than a few parts in 10(exp 10). We will discuss the methodology of the technique in detail, present a broad range of simulation results, and provide preprints of a journal article currently in press.

  12. A New Continuous Cooling Transformation Diagram for AISI M4 High-Speed Tool Steel

    NASA Astrophysics Data System (ADS)

    Briki, Jalel; Ben Slima, Souad

    2008-12-01

    The increasing evolution of dilatometric techniques now allows for the identification of structural transformations with very low signal. The use of dilatometric techniques coupled with more common techniques, such as metallographic, hardness testing, and x-ray diffraction allows to plot a new CCT diagram for AISI M4 high-speed tool steel. This diagram is useful for a better selection of alternate solutions, hardening, and tempering heat treatments. More accurate determination of the various fields of transformation of austenite during its cooling was made. The precipitation of carbides highlighted at high temperature is at the origin of the martrensitic transformation into two stages (splitting phenomena). For slow cooling rates, it was possible to highlight the ferritic, pearlitic, and bainitic transformation.

  13. Splitting the mind within the individual, nation and economy: reflections on the struggle for integration in post-war Germany.

    PubMed

    Plänkers, Tomas

    2015-02-01

    With respect to theorisations of psychical splitting, this paper explores the psychical mechanisms that underlie different forms of social splitting. The paper first outlines Freud's and Kleins different theorisations of the psychical mechanisms of splitting, where the good is split from the bad, the inside split from the outside, and the painful disavowed. I then consider the psychical mechanisms of splitting that underlie ideological supports of certain social systems, specifically that of National Socialist Germany, East Germany during the Cold War period, and neoliberal capitalism. Here, I consider ideological splits between good and evil, the relation between external and internal splits, the relation between geographical, social and internal splitting, as well as splitting as disavowal of the other. Copyright © 2015 Institute of Psychoanalysis.

  14. Bi-tangential hybrid IMRT for sparing the shoulder in whole breast irradiation.

    PubMed

    Farace, P; Deidda, M A; Iamundo de Cumis, I; Iamundo de Curtis, I; Deiana, E; Farigu, R; Lay, G; Porru, S

    2013-11-01

    A bi-tangential technique is proposed to reduce undesired doses to the shoulder produced by standard tangential irradiation. A total of 6 patients affected by shoulder pain and reduced functional capacity after whole-breast irradiation were retrospectively analysed. The standard tangential plan used for treatment was compared with (1) a single bi-tangential plan where, to spare the shoulder, the lateral open tangent was split into two half-beams at isocentre, with the superior portion rotated by 10-20° medially with respect to the standard lateral beam; (2) a double bi-tangential plan, where both the tangential open beams were split. The planning target volume (PTV) coverage and the dose to the portion of muscles and axilla included in the standard tangential beams were compared. PTV95 % of standard plan (91.9 ± 3.8) was not significantly different from single bi-tangential plan (91.8 ± 3.4); a small but significant (p < 0.01) decrease was observed with the double bi-tangential plan (90.1 ± 3.7). A marked dose reduction to the muscle was produced by the single bi-tangential plan around 30-40 Gy. The application of the double bi-tangential technique further reduced the volume receiving around 20 Gy, but did not markedly affect the higher doses. The dose to the axilla was reduced both in the single and the double bi-tangential plans. The single bi-tangential technique would have been able to reduce the dose to shoulder and axilla, without compromising target coverage. This simple technique is valuable for irradiation after axillary lymph node dissection or in patients without dissection due to negative or low-volume sentinel lymph node disease.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bateman, V.I.; Bell, R.G. III; Brown, F.A.

    Sandia National Laboratories (SNL) designs mechanical systems with electronics that must survive high shock environments. These mechanical systems include penetrators that must survive soil, rock, and ice penetration, nuclear transportation casks that must survive transportation environments, and laydown weapons that must survive delivery impact of 125-fps. These mechanical systems contain electronics that may operate during and after the high shock environment and that must be protected from the high shock environments. A study has been started to improve the packaging techniques for the advanced electronics utilized in these mechanical systems because current packaging techniques are inadequate for these more sensitivemore » electronics. In many cases, it has been found that the packaging techniques currently used not only do not mitigate the shock environment but actually amplify the shock environment. An ambitious goal for this packaging study is to avoid amplification and possibly attenuate the shock environment before it reaches the electronics contained in the various mechanical system. As part of the investigation of packaging techniques, a two part study of shock mitigating materials is being conducted. This paper reports the first part of the shock mitigating materials study. A study to compare three thicknesses (0.125, 0.250, and 0.500 in.) of seventeen, unconfined materials for their shock mitigating characteristics has been completed with a split Hopkinson bar configuration. The nominal input as measured by strain gages on the incident Hopkinson bar is 50 fps {at} 100 {micro}s for these tests. It is hypothesized that a shock mitigating material has four purposes: to lengthen the shock pulse, to attenuate the shock pulse, to mitigate high frequency content in the shock pulse, and to absorb energy. Both time domain and frequency domain analyses of the split Hopkinson bar data have been performed to compare the materials` achievement of these purposes.« less

  16. Mössbauer and XRD study of novel quaternary Sn-Fe-Co-Ni electroplated alloy

    NASA Astrophysics Data System (ADS)

    Kuzmann, E.; Sziráki, L.; Stichleutner, S.; Homonnay, Z.; Lak, G. B.; El-Sharif, M.; Chisholm, C. U.

    2017-11-01

    Constant current electrochemical deposition technique was used to obtain quaternary alloys of Sn-Fe-Co-Ni from a gluconate electrolyte, which to date have not been reported in the literature. For the characterization of electroplated alloys, 57Fe and 119Sn Conversion Electron Mössbauer Spectroscopy (CEMS), XRD and SEM/EDAX were used. XRD revealed the amorphous character of the novel Sn-Fe-Co-Ni electrodeposited alloys. 57Fe Mössbauer spectrum of quaternary deposit with composition of 37.0 at% Sn, 38.8 at% Fe, 16.8 at% Co and 7.4 at% Ni displayed a magnetically split sextet (B = 28.9T) with broad lines typical of iron bearing ferromagnetic amorphous alloys. Magnetically split 119Sn spectra reflecting a transferred hyperfine field (B = 2.3T) were also observed. New quaternary Sn-Fe-Co-Ni alloys were successfully prepared.

  17. Analysis of cosmetic residues on a single human hair by ATR FT-IR microspectroscopy

    NASA Astrophysics Data System (ADS)

    Pienpinijtham, Prompong; Thammacharoen, Chuchaat; Naranitad, Suwimol; Ekgasit, Sanong

    2018-05-01

    In this work, ATR FT-IR spectra of single human hair and cosmetic residues on hair surface are successfully collected using a homemade dome-shaped Ge μIRE accessary installed on an infrared microscope. By collecting ATR spectra of hairs from the same person, the spectral patterns are identical and superimposed while different spectral features are observed from ATR spectra of hairs collected from different persons. The spectral differences depend on individual hair characteristics, chemical treatments, and cosmetics on hair surface. The "Contact-and-Collect" technique that transfers remarkable materials on the hair surface to the tip of the Ge μIRE enables an identification of cosmetics on a single hair. Moreover, the differences between un-split and split hairs are also studied in this report. These highly specific spectral features can be employed for unique identification or for differentiation of hairs based on the molecular structures of hairs and cosmetics on hairs.

  18. Electron spin resonance and spin-valley physics in a silicon double quantum dot.

    PubMed

    Hao, Xiaojie; Ruskov, Rusko; Xiao, Ming; Tahan, Charles; Jiang, HongWen

    2014-05-14

    Silicon quantum dots are a leading approach for solid-state quantum bits. However, developing this technology is complicated by the multi-valley nature of silicon. Here we observe transport of individual electrons in a silicon CMOS-based double quantum dot under electron spin resonance. An anticrossing of the driven dot energy levels is observed when the Zeeman and valley splittings coincide. A detected anticrossing splitting of 60 MHz is interpreted as a direct measure of spin and valley mixing, facilitated by spin-orbit interaction in the presence of non-ideal interfaces. A lower bound of spin dephasing time of 63 ns is extracted. We also describe a possible experimental evidence of an unconventional spin-valley blockade, despite the assumption of non-ideal interfaces. This understanding of silicon spin-valley physics should enable better control and read-out techniques for the spin qubits in an all CMOS silicon approach.

  19. On advanced configuration enhance adaptive system optimization

    NASA Astrophysics Data System (ADS)

    Liu, Hua; Ding, Quanxin; Wang, Helong; Guo, Chunjie; Chen, Hongliang; Zhou, Liwei

    2017-10-01

    For aim to find an effective method to structure to enhance these adaptive system with some complex function and look forward to establish an universally applicable solution in prototype and optimization. As the most attractive component in adaptive system, wave front corrector is constrained by some conventional technique and components, such as polarization dependence and narrow working waveband. Advanced configuration based on a polarized beam split can optimized energy splitting method used to overcome these problems effective. With the global algorithm, the bandwidth has been amplified by more than five times as compared with that of traditional ones. Simulation results show that the system can meet the application requirements in MTF and other related criteria. Compared with the conventional design, the system has reduced in volume and weight significantly. Therefore, the determining factors are the prototype selection and the system configuration, Results show their effectiveness.

  20. Mechanical splitting of microtubules into protofilament bundles by surface-bound kinesin-1

    DOE PAGES

    VanDelinder, Virginia; Adams, Peter G.; Bachand, George D.

    2016-12-21

    The fundamental biophysics of gliding microtubule (MT) motility by surface-tethered kinesin-1 motor proteins has been widely studied, as well as applied to capture and transport analytes in bioanalytical microdevices. In these systems, phenomena such as molecular wear and fracture into shorter MTs have been reported due the mechanical forces applied on the MT during transport. In the present work, we show that MTs can be split longitudinally into protofilament bundles (PFBs) by the work performed by surface-bound kinesin motors. We examine the properties of these PFBs using several techniques (e.g., fluorescence microscopy, SEM, AFM), and show that the PFBs continuemore » to be mobile on the surface and display very high curvature compared to MT. Further, higher surface density of kinesin motors and shorter kinesin-surface tethers promote PFB formation, whereas modifying MT with GMPCPP or higher paclitaxel concentrations did not affect PFB formation.« less

  1. Coolant mixing in LMFBR rod bundles and outlet plenum mixing transients. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Todreas, N.E.; Cheng, S.K.; Basehore, K.

    1984-08-01

    This project principally undertook the investigation of the thermal hydraulic performance of wire wrapped fuel bundles of LMFBR configuration. Results obtained included phenomenological models for friction factors, flow split and mixing characteristics; correlations for predicting these characteristics suitable for insertion in design codes; numerical codes for analyzing bundle behavior both of the lumped subchannel and distributed parameter categories and experimental techniques for pressure velocity, flow split, salt conductivity and temperature measurement in water cooled mockups of bundles and subchannels. Flow regimes investigated included laminar, transition and turbulent flow under forced convection and mixed convection conditions. Forced convections conditions were emphasized.more » Continuing efforts are underway at MIT to complete the investigation of the mixed convection regime initiated here. A number of investigations on outlet plenum behavior were also made. The reports of these investigations are identified.« less

  2. Security of subcarrier wave quantum key distribution against the collective beam-splitting attack.

    PubMed

    Miroshnichenko, G P; Kozubov, A V; Gaidash, A A; Gleim, A V; Horoshko, D B

    2018-04-30

    We consider a subcarrier wave quantum key distribution (QKD) system, where quantum encoding is carried out at weak sidebands generated around a coherent optical beam as a result of electro-optical phase modulation. We study security of two protocols, B92 and BB84, against one of the most powerful attacks for this class of systems, the collective beam-splitting attack. Our analysis includes the case of high modulation index, where the sidebands are essentially multimode. We demonstrate numerically and experimentally that a subcarrier wave QKD system with realistic parameters is capable of distributing cryptographic keys over large distances in presence of collective attacks. We also show that BB84 protocol modification with discrimination of only one state in each basis performs not worse than the original BB84 protocol in this class of QKD systems, thus significantly simplifying the development of cryptographic networks using the considered QKD technique.

  3. A new splitting scheme to the discrete Boltzmann equation for non-ideal gases on non-uniform meshes

    NASA Astrophysics Data System (ADS)

    Patel, Saumil; Lee, Taehun

    2016-12-01

    We present a novel numerical procedure for solving the discrete Boltzmann equations (DBE) on non-uniform meshes. Our scheme is based on the Strang splitting method where we seek to investigate two-phase flow applications. In this note, we investigate the onset of parasitic currents which arise in many computational two-phase algorithms. To the best of our knowledge, the results presented in this work show, for the first time, a spectral element discontinuous Galerkin (SEDG) discretization of a discrete Boltzmann equation which successfully eliminates parasitic currents on non-uniform meshes. With the hope that this technique can be used for applications in complex geometries, calculations are performed on non-uniform mesh distributions by using high-order (spectral), body-fitting quadrilateral elements. Validation and verification of our work is carried out by comparing results against the classical 2D Young-Laplace law problem for a static drop.

  4. Flexible ultra-wideband antenna incorporated with metamaterial structures: multiple notches for chipless RFID application

    NASA Astrophysics Data System (ADS)

    Jalil, M. E.; Rahim, M. K. A.; Samsuri, N. A.; Dewan, R.; Kamardin, K.

    2017-01-01

    A coplanar waveguide (CPW) ultra-wideband (UWB) antenna incorporated with metamaterial—split ring resonator structure—that operates from 3.0 to 12.0 GHz is proposed for chipless RFID tag. The 30 mm × 40 mm flexible chipless RFID tag is designed on the fleece substrate ( ɛ r = 1.35, thickness = 1 mm and tan δ = 0.025). A six-slotted modified complementary split ring resonator (MCSRR) is introduced into the ultra-wideband antenna to produce multiple band notches at 3.0, 4.0, 5.0, 6.0 and 7.0 GHz. The frequency shifting technique is introduced for designing a high-capacity chipless RFID tag with compact size. Each MCSRR is able to code in four different allocations (00, 01, 10 and 11). To achieve encoding of 10-bits data (10,234 number), six MCSRRs are proposed with three-slotted MCSRR in the radiator and three-slotted MCSRR in the ground plane.

  5. Mössbauer effect studies of Fe-C combinatorially sputtered thin films

    NASA Astrophysics Data System (ADS)

    Al-Maghrabi, M. A.; Sanderson, R. J.; Dunlap, R. A.

    2013-08-01

    Alloys of Fe1- x C x were produced using combinatorial sputtering methods. The composition of the films as a function of position was determined using electron microprobe techniques and the results have shown that a composition range of about 0.35 < x < 0.75 was obtained. X-ray diffraction methods were employed to study the structure of the thin films and showed that all portions of the films were amorphous or nanostructured. Room temperature 57Fe Mössbauer spectroscopy was utilized to study the atomic environment around the Fe atoms. Hyperfine field distributions of ferromagnetic alloys, as extracted from the Mössbauer analysis, suggested the existence of two classes of Fe sites: (1) classes of Fe sites that have primarily Fe neighbours corresponding to a high-field component in the distribution and (2) classes of Fe sites that have a greater number of C neighbours, corresponding to a low-field component. The magnetic splitting decreased as a function of increasing carbon concentration and alloys with x greater than about 0.68 were primarily paramagnetic in nature. These spectra exhibited distributions of quadrupole splitting with mean splitting in excess of 1.0 mm/s. This indicates a higher degree of local asymmetry around the Fe sites than typically seen in other Fe-metalloid systems.

  6. Low-level water vapor fields from the VAS split-window channels at 11 and 12 microns

    NASA Technical Reports Server (NTRS)

    Chesters, D.; Uccellini, L. W.; Robinson, W.

    1983-01-01

    Originally, the VAS split window channels were designed to use the differential water vapor absorption between 11 and 12 microns to estimate sea surface temperature by correcting for the radiometric losses caused by atmospheric moisture. It is shown that it is possible to reverse the procedure in order to estimate the vertically integrated low level moisture content with the background surface (skin) temperature removed, even over the bright, complex background of the land. Because the lower troposphere's water vapor content is an important factor in convective instability, the derived fields are of considerable value to mesoscale meteorology. Moisture patterns are available as quantitative fields (centimeters of precipitable water) at full VAS resolution (as fine as 7 kilometers horizontal resolution every 15 minutes), and are readily converted to image format for false color movies. The technique, demonstrated with GOES-5, uses a sequence of split window radiances taken once every 3 hours from dawn to dusk over the Eastern and Central United States. The algorithm is calibrated with the morning radiosonde sites embedded within the first VAS radiance field; then, entire moisture fields are calculated at all five observation times. Cloud contamination is removed by rejecting any pixel having a radiance less than the atmospheric brightness determined at the radiosonde sites.

  7. Biomechanical analysis of posteromedial tibial plateau split fracture fixation.

    PubMed

    Zeng, Zhi-Min; Luo, Cong-Feng; Putnis, Sven; Zeng, Bing-Fang

    2011-01-01

    The purpose of this study was to compare the biomechanical strength of four different fixation methods for a posteromedial tibial plateau split fracture. Twenty-eight tibial plateau fractures were simulated using right-sided synthetic tibiae models. Each fracture model was randomly instrumented with one of the four following constructs, anteroposterior lag-screws, an anteromedial limited contact dynamic compression plate (LC-DCP), a lateral locking plate, or a posterior T-shaped buttress plate. Vertical subsidence of the posteromedial fragment was measured from 500 N to 1500 N during biomechanical testing, the maximum load to failure was also determined. It was found that the posterior T-shaped buttress plate allowed the least subsidence of the posteromedial fragment and produced the highest mean failure load than each of the other three constructs (P=0.00). There was no statistical significant difference between using lag screws or an anteromedial LC-DCP construct for the vertical subsidence at a 1500 N load and the load to failure (P>0.05). This study showed that a posterior-based buttress technique is biomechanically the most stable in-vitro fixation method for posteromedial split tibial plateau fractures, with AP screws and anteromedial-based LC-DCP are not as stable for this type of fracture. Copyright © 2010 Elsevier B.V. All rights reserved.

  8. Modelling and investigation of partial wetting surfaces for drop dynamics using lattice Boltzmann method

    NASA Astrophysics Data System (ADS)

    Pravinraj, T.; Patrikar, Rajendra

    2017-07-01

    Partial wetting surfaces and its influence on the droplet movement of micro and nano scale being contemplated for many useful applications. The dynamics of the droplet usually analyzed with a multiphase lattice Boltzmann method (LBM). In this paper, the influence of partial wetting surface on the dynamics of droplet is systematically analyzed for various cases. Splitting of droplets due to chemical gradient of the surface is studied and analyses of splitting time for various widths of the strips for different Weber numbers are computed. With the proposed model one can tune the splitting volume and time by carefully choosing a strip width and droplet position. The droplet spreading on chemically heterogeneous surfaces shows that the spreading can be controlled not only by parameters of Weber number but also by tuning strip width ratio. The transportation of the droplet from hydrophobic surface to hydrophilic surface due to chemical gradient is simulated and analyzed using our hybrid thermodynamic-image processing technique. The results prove that with the progress of time the surface free energy decreases with increase in spreading area. Finally, the transportation of a droplet on microstructure gradient is demonstrated. The model explains the temporal behaviour of droplet during the spreading, recoiling and translation along with tracking of contact angle hysteresis phenomenon.

  9. ["In-situ split" (ISS) liver resection: new aspects of technique and indication].

    PubMed

    Lang, S A; Loss, M; Schlitt, H J

    2014-04-01

    The combination of right portal vein ligation with complete parenchyma dissection ("in-situ split", ISS) for rapid hypertrophy induction of the left-lateral liver lobe is a novel strategy to convert primarily irresectable liver tumours into a resectable stage. Available data so far show a 60-80 % growth induction of the remnant liver within 7(- 9) days. Certainly, a novel concept that comprises two operations within a very short time period raises questions. Based on the very few literature reports that have been published so far, as well as our own experience, we here discuss technical issues such as the use of a plastic sheet on the resection margin, the possibility of laparoscopic dissection and the timing of the second operation. Moreover, aspects of the preoperative diagnostic work-up that is necessary are assessed. Finally, open questions, e.g., concerning the influence of preoperative chemotherapy and the use of ISS in patients with cirrhosis are evaluated. In summary, the assessment of chances and risks of this novel concept with regard to indication and technical issues helps to provide the potentially curative option of the "in-situ split" procedure to more patients with marginal or even irresectable liver tumours. Georg Thieme Verlag KG Stuttgart · New York.

  10. A splitting integration scheme for the SPH simulation of concentrated particle suspensions

    NASA Astrophysics Data System (ADS)

    Bian, Xin; Ellero, Marco

    2014-01-01

    Simulating nearly contacting solid particles in suspension is a challenging task due to the diverging behavior of short-range lubrication forces, which pose a serious time-step limitation for explicit integration schemes. This general difficulty limits severely the total duration of simulations of concentrated suspensions. Inspired by the ideas developed in [S. Litvinov, M. Ellero, X.Y. Hu, N.A. Adams, J. Comput. Phys. 229 (2010) 5457-5464] for the simulation of highly dissipative fluids, we propose in this work a splitting integration scheme for the direct simulation of solid particles suspended in a Newtonian liquid. The scheme separates the contributions of different forces acting on the solid particles. In particular, intermediate- and long-range multi-body hydrodynamic forces, which are computed from the discretization of the Navier-Stokes equations using the smoothed particle hydrodynamics (SPH) method, are taken into account using an explicit integration; for short-range lubrication forces, velocities of pairwise interacting solid particles are updated implicitly by sweeping over all the neighboring pairs iteratively, until convergence in the solution is obtained. By using the splitting integration, simulations can be run stably and efficiently up to very large solid particle concentrations. Moreover, the proposed scheme is not limited to the SPH method presented here, but can be easily applied to other simulation techniques employed for particulate suspensions.

  11. A hybrid 3D spatial access method based on quadtrees and R-trees for globe data

    NASA Astrophysics Data System (ADS)

    Gong, Jun; Ke, Shengnan; Li, Xiaomin; Qi, Shuhua

    2009-10-01

    3D spatial access method for globe data is very crucial technique for virtual earth. This paper presents a brand-new maintenance method to index 3d objects distributed on the whole surface of the earth, which integrates the 1:1,000,000- scale topographic map tiles, Quad-tree and R-tree. Furthermore, when traditional methods are extended into 3d space, the performance of spatial index deteriorates badly, for example 3D R-tree. In order to effectively solve this difficult problem, a new algorithm of dynamic R-tree is put forward, which includes two sub-procedures, namely node-choosing and node-split. In the node-choosing algorithm, a new strategy is adopted, not like the traditional mode which is from top to bottom, but firstly from bottom to top then from top to bottom. This strategy can effectively solve the negative influence of node overlap. In the node-split algorithm, 2-to-3 split mode substitutes the traditional 1-to-2 mode, which can better concern the shape and size of nodes. Because of the rational tree shape, this R-tree method can easily integrate the concept of LOD. Therefore, it will be later implemented in commercial DBMS and adopted in time-crucial 3d GIS system.

  12. Oriented epitaxial TiO2 nanowires for water splitting

    NASA Astrophysics Data System (ADS)

    Hou, Wenting; Cortez, Pablo; Wuhrer, Richard; Macartney, Sam; Bozhilov, Krassimir N.; Liu, Rong; Sheppard, Leigh R.; Kisailus, David

    2017-06-01

    Highly oriented epitaxial rutile titanium dioxide (TiO2) nanowire arrays have been hydrothermally grown on polycrystalline TiO2 templates with their orientation dependent on the underlying TiO2 grain. Both the diameter and areal density of the nanowires were tuned by controlling the precursor concentration, and the template surface energy and roughness. Nanowire tip sharpness was influenced by precursor solubility and diffusivity. A new secondary ion mass spectrometer technique has been developed to install additional nucleation sites in single crystal TiO2 templates and the effect on nanowire growth was probed. Using the acquired TiO2 nanowire synthesis knowhow, an assortment of nanowire arrays were installed upon the surface of undoped TiO2 photo-electrodes and assessed for their photo-electrochemical water splitting performance. The key result obtained was that the presence of short and dispersed nanowire arrays significantly improved the photocurrent when the illumination intensity was increased from 100 to 200 mW cm-2. This is attributed to the alignment of the homoepitaxially grown nanowires to the [001] direction, which provides the fastest charge transport in TiO2 and an improved pathway for photo-holes to find water molecules and undertake oxidation. This result lays a foundation for achieving efficient water splitting under conditions of concentrated solar illumination.

  13. Split-luciferase complementary assay: applications, recent developments, and future perspectives.

    PubMed

    Azad, Taha; Tashakor, Amin; Hosseinkhani, Saman

    2014-09-01

    Bioluminescent systems are considered as potent reporter systems for bioanalysis since they have specific characteristics, such as relatively high quantum yields and photon emission over a wide range of colors from green to red. Biochemical events are mostly accomplished through large protein machines. These molecular complexes are built from a few to many proteins organized through their interactions. These protein-protein interactions are vital to facilitate the biological activity of cells. The split-luciferase complementation assay makes the study of two or more interacting proteins possible. In this technique, each of the two domains of luciferase is attached to each partner of two interacting proteins. On interaction of those proteins, luciferase fragments are placed close to each other and form a complemented luciferase, which produces a luminescent signal. Split luciferase is an effective tool for assaying biochemical metabolites, where a domain or an intact protein is inserted into an internally fragmented luciferase, resulting in ligand binding, which causes a change in the emitted signals. We review the various applications of this novel luminescent biosensor in studying protein-protein interactions and assaying metabolites involved in analytical biochemistry, cell communication and cell signaling, molecular biology, and the fate of the whole cell, and show that luciferase-based biosensors are powerful tools that can be applied for diagnostic and therapeutic purposes.

  14. Investigating crater lake warming using ASTER thermal imagery: Case studies at Ruapehu, Poás, Kawah Ijen, and Copahué Volcanoes

    NASA Astrophysics Data System (ADS)

    Trunk, Laura; Bernard, Alain

    2008-12-01

    A two-channel or split-window algorithm designed to correct for atmospheric conditions was applied to thermal images taken by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) of Lake Yugama on Kusatsu-Shirane volcano in Japan in order to measure the temperature of its crater lake. These temperature calculations were validated using lake water temperatures that were collected on the ground. Overall, the agreement between the temperatures calculated using the split-window method and ground truth is quite good, typically ± 1.5 °C for cloud-free images. Data from fieldwork undertaken in the summer of 2004 at Kusatsu-Shirane allow a comparison of ground-truth data with the radiant temperatures measured using ASTER imagery. Further images were analyzed of Ruapehu, Poás, Kawah Ijen, and Copahué volcanoes to acquire time-series of lake temperatures. A total of 64 images of these 4 volcanoes covering a wide range of geographical locations and climates were analyzed. Results of the split-window algorithm applied to ASTER images are reliable for monitoring thermal changes in active volcanic lakes. These temperature data, when considered in conjunction with traditional volcano monitoring techniques, lead to a better understanding of whether and how thermal changes in crater lakes aid in eruption forecasting.

  15. StackSplit - a plugin for multi-event shear wave splitting analyses in SplitLab

    NASA Astrophysics Data System (ADS)

    Grund, Michael

    2017-04-01

    The SplitLab package (Wüstefeld et al., Computers and Geosciences, 2008), written in MATLAB, is a powerful and widely used tool for analysing seismological shear wave splitting of single event measurements. However, in many cases, especially temporary station deployments close to seaside or for recordings affected by strong anthropogenic noise, only multi-event approaches provide stable and reliable splitting results. In order to extend the original SplitLab environment for such analyses, I present the StackSplit plugin that can easily be implemented within the well accepted main program. StackSplit grants easy access to several different analysis approaches within SplitLab, including a new multiple waveform based inversion method as well as the most established standard stacking procedures. The possibility to switch between different analysis approaches at any time allows the user for the most flexible processing of individual multi-event splitting measurements for a single recording station. Besides the provided functions of the plugin, no other external program is needed for the multi-event analyses since StackSplit performs within the available SplitLab structure.

  16. Splitting of IVP bovine blastocyst affects morphology and gene expression of resulting demi-embryos during in vitro culture and in vivo elongation.

    PubMed

    Velasquez, Alejandra E; Castro, Fidel O; Veraguas, Daniel; Cox, Jose F; Lara, Evelyn; Briones, Mario; Rodriguez-Alvarez, Lleretny

    2016-02-01

    Embryo splitting might be used to increase offspring yield and for molecular analysis of embryo competence. How splitting affects developmental potential of embryos is unknown. This research aimed to study the effect of bovine blastocyst splitting on morphological and gene expression homogeneity of demi-embryos and on embryo competence during elongation. Grade I bovine blastocyst produced in vitro were split into halves and distributed in nine groups (3 × 3 setting according to age and stage before splitting; age: days 7-9; stage: early, expanded and hatched blastocysts). Homogeneity and survival rate in vitro after splitting (12 h, days 10 and 13) and the effect of splitting on embryo development at elongation after embryo transfer (day 17) were assessed morphologically and by RT-qPCR. The genes analysed were OCT4, SOX2, NANOG, CDX2, TP1, TKDP1, EOMES, and BAX. Approximately 90% of split embryos had a well conserved defined inner cell mass (ICM), 70% of the halves had similar size with no differences in gene expression 12 h after splitting. Split embryos cultured further conserved normal and comparable morphology at day 10 of development; this situation changes at day 13 when embryo morphology and gene expression differed markedly among demi-embryos. Split and non-split blastocysts were transferred to recipient cows and were recovered at day 17. Fifty per cent of non-split embryos were larger than 100 mm (33% for split embryos). OCT4, SOX2, TP1 and EOMES levels were down-regulated in elongated embryos derived from split blastocysts. In conclusion, splitting day-8 blastocysts yields homogenous demi-embryos in terms of developmental capability and gene expression, but the initiation of the filamentous stage seems to be affected by the splitting.

  17. Forming heterojunctions at the nanoscale for improved photoelectrochemical water splitting by semiconductor materials: case studies on hematite.

    PubMed

    Mayer, Matthew T; Lin, Yongjing; Yuan, Guangbi; Wang, Dunwei

    2013-07-16

    In order for the future energy needs of humanity to be adequately and sustainably met, alternative energy techniques such as artificial photosynthesis need to be made more efficient and therefore commercially viable. On a grand scale, the energies coming to and leaving from the earth are balanced. With the fast increasing waste heat produced by human activities, the balance may be shifted to threaten the ecosystem in which we reside. To avoid such dire consequences, it is necessary to power human activities using energy derived from the incoming source, which is predominantly solar irradiation. Indeed, most life on the surface of the earth is supported, directly or indirectly, by photosynthesis that harvests solar energy and stores it in chemical bonds for redistribution. Being able to mimic the process and perform it at high efficiencies using low-cost materials has significant implications. Such an understanding is a major intellectual driving force that motivates research by us and many others. From a thermodynamic perspective, the key energy conversion step in natural photosynthesis happens in the light reactions, where H₂O splits to give O₂ and reactive protons. The capability of carrying out direct sunlight-driven water splitting with high efficiency is therefore fundamentally important. We are particularly interested in doing so using inorganic semiconductor materials because they offer the promise of durability and low cost. In this Account, we share our recent efforts in bringing semiconductor-based water splitting reactions closer to reality. More specifically, we focus on earth-abundant oxide semiconductors such as Fe₂O₃ and work on improving the performance of these materials as photoelectrodes for photoelectrochemical reactions. Using hematite (α-Fe₂O₃) as an example, we examine how the main problems that limit the performance, namely, the short hole collection distance, poor light absorption near the band edge, and mismatch of the band edge energetics with those of water redox reactions, can in principle be addressed by adding nanoscale charge collectors, forming buried junctions, and including additional light absorbers. These results highlight the power of forming homo- or heterojunctions at the nanoscale, which permits us to engineer the band structures of semiconductors to the specific application of water splitting. The key enabling factor is our ability to synthesize materials with precise control over the dimensions, crystallinity, and, most importantly, the interface quality at the nanoscale. While being able to tailor specific properties on a simple, earth-abundant device is not straightforward, the approaches we report here take significant steps towards efficient artificial photosynthesis, an energy harvesting technique necessary for the well-being of humanity.

  18. The GIST Model for Selection and Modification of Scientific Research for the College Teaching Laboratory Based on Root Competition Investigations

    ERIC Educational Resources Information Center

    Elliott, Shannon Snyder

    2007-01-01

    The purpose of this study is to first develop an 8-week college teaching module based on root competition literature. The split-root technique is adapted for the teaching laboratory, and the Sugar Ann English pea (Pisum sativum var. Sugar Ann English) is selected as the species of interest prior to designing experiments, either original or…

  19. Planar-Processed Polymer Transistors.

    PubMed

    Xu, Yong; Sun, Huabin; Shin, Eul-Yong; Lin, Yen-Fu; Li, Wenwu; Noh, Yong-Young

    2016-10-01

    Planar-processed polymer transistors are proposed where the effective charge injection and the split unipolar charge transport are all on the top surface of the polymer film, showing ideal device characteristics with unparalleled performance. This technique provides a great solution to the problem of fabrication limitations, the ambiguous operating principle, and the performance improvements in practical applications of conjugated-polymer transistors. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Controlling electronic couplings with tunable long wavelength pulses: Study of Autler-Townes splitting and XUV emission spectra

    NASA Astrophysics Data System (ADS)

    Harkema, Nathan; Liao, Chen-Ting; Sandhu, Arvinder

    2017-04-01

    Attosecond transient absorption spectroscopy (ATAS) enables the study of excited electron dynamics with unprecedented temporal and energy resolution. Many ATAS experiments use an extreme ultraviolet (XUV) pump pulse and a near-infrared (NIR) probe fixed at the fundamental laser frequency ( 800 nm) to study the light induced effects on electronic structure of atoms and molecules. We extend the technique by using an optical parametric amplifier in one arm of our setup, which allows us to independently tune the frequency of the probe pulse from 1200 to 1800 nm. These long-wavelength pulses allow us to explore a new regime, where we can control the couplings between nearby electronic states to alter the transient absorption lineshapes in atoms. We use this technique to investigate the 4p-3s detuning dependent Autler-Townes splitting of the 4p state in Helium. Light induced Floquet structures extending into the continuum are observed in our study. We demonstrate new tunable XUV emission channels from four-wave mixing processes, and the efficiency of these emissions can be strongly enhanced through resonant couplings. The tunable IR induced electronic couplings are also used to influence the autoionization dynamics in Argon. This work is supported by NSF Grant No. PHY-1505556 and ARO Grant No. W911NF-14-1-0383.

  1. Electrodeposition of Sn-Ni Alloy Coatings for Water-Splitting Application from Alkaline Medium

    NASA Astrophysics Data System (ADS)

    Shetty, Sandhya; Hegde, A. Chitharanjan

    2017-02-01

    In this work, Sn-Ni alloy coatings were developed onto the surface of copper from a newly formulated electrolytic bath by a simple and cost-effective electrodeposition technique using gelatin as an additive. The electrocatalytic behavior of coatings deposited at different current densities (c.d.'s) for water-splitting applications, in terms of hydrogen evolution reaction (HER) and oxygen evolution reaction (OER), has been researched. The experimental results showed that the electrocatalytic activity of Sn-Ni coatings has a close relationship with its composition, surface morphology, and phase structure depending on the c.d. used, supported by scanning electron microscopy (SEM-EDX) and X-ray diffraction (XRD) analyses. Cyclic voltammetry and chronopotentiometry techniques have demonstrated that Sn-Ni alloy deposited at 4.0 A dm-2 (having 37.6 wt pct Ni) and 1.0 A dm-2 (having 19.6 wt pct Ni) exhibit, respectively, the highest electrocatalytic behavior for HER and OER in 1.0-M KOH solution. Sn-Ni alloy coatings were found to be stable under working conditions of electrolysis, confirmed by electrochemical corrosion tests. High electrocatalytic activity of Sn-Ni alloy coatings for both HER and OER is specific to their composition, surface morphology, and active surface area.

  2. Fast and memory efficient text image compression with JBIG2.

    PubMed

    Ye, Yan; Cosman, Pamela

    2003-01-01

    In this paper, we investigate ways to reduce encoding time, memory consumption and substitution errors for text image compression with JBIG2. We first look at page striping where the encoder splits the input image into horizontal stripes and processes one stripe at a time. We propose dynamic dictionary updating procedures for page striping to reduce the bit rate penalty it incurs. Experiments show that splitting the image into two stripes can save 30% of encoding time and 40% of physical memory with a small coding loss of about 1.5%. Using more stripes brings further savings in time and memory but the return diminishes. We also propose an adaptive way to update the dictionary only when it has become out-of-date. The adaptive updating scheme can resolve the time versus bit rate tradeoff and the memory versus bit rate tradeoff well simultaneously. We then propose three speedup techniques for pattern matching, the most time-consuming encoding activity in JBIG2. When combined together, these speedup techniques can save up to 75% of the total encoding time with at most 1.7% of bit rate penalty. Finally, we look at improving reconstructed image quality for lossy compression. We propose enhanced prescreening and feature monitored shape unifying to significantly reduce substitution errors in the reconstructed images.

  3. Selective processing of auditory evoked responses with iterative-randomized stimulation and averaging: A strategy for evaluating the time-invariant assumption.

    PubMed

    Valderrama, Joaquin T; de la Torre, Angel; Medina, Carlos; Segura, Jose C; Thornton, A Roger D

    2016-03-01

    The recording of auditory evoked potentials (AEPs) at fast rates allows the study of neural adaptation, improves accuracy in estimating hearing threshold and may help diagnosing certain pathologies. Stimulation sequences used to record AEPs at fast rates require to be designed with a certain jitter, i.e., not periodical. Some authors believe that stimuli from wide-jittered sequences may evoke auditory responses of different morphology, and therefore, the time-invariant assumption would not be accomplished. This paper describes a methodology that can be used to analyze the time-invariant assumption in jittered stimulation sequences. The proposed method [Split-IRSA] is based on an extended version of the iterative randomized stimulation and averaging (IRSA) technique, including selective processing of sweeps according to a predefined criterion. The fundamentals, the mathematical basis and relevant implementation guidelines of this technique are presented in this paper. The results of this study show that Split-IRSA presents an adequate performance and that both fast and slow mechanisms of adaptation influence the evoked-response morphology, thus both mechanisms should be considered when time-invariance is assumed. The significance of these findings is discussed. Crown Copyright © 2016. Published by Elsevier B.V. All rights reserved.

  4. Distal biceps tendon rupture reconstruction using muscle-splitting double-incision approach

    PubMed Central

    Tarallo, Luigi; Mugnai, Raffaele; Zambianchi, Francesco; Adani, Roberto; Catani, Fabio

    2014-01-01

    AIM: To evaluate the clinical and functional results after repair of distal biceps tendon tears, following the Morrey’s modified double-incision approach. METHODS: We retrospectively reviewed 47 patients with distal rupture of biceps brachii treated between 2003 and 2012 in our Orthopedic Department with muscle-splitting double-incision technique. Outcome measures included the Mayo elbow performance, the DASH questionnaire, patient’s satisfaction, elbow and forearm motion, grip strength and complications occurrence. RESULTS: At an average 18 mo follow-up (range, 7 mo-10 years) the average Mayo elbow performance and DASH score were respectively 97.2 and 4.8. The elbow flexion range was 94%, extension was -2°, supination was 93% and pronation 96% compared with the uninjured limb. The mean grip strength, expressed as percentage of respective contralateral limb, was 83%. The average patient satisfaction rating on a Likert scale (from 0 to 10) was 9.4. The following complications were observed: 3 cases of heterotopic ossification (6.4%), one (2.1%) re-rupture of the tendon at the site of reattachment and 2 cases (4.3%) of posterior interosseous nerve palsy. No complication required further surgical treatment. CONCLUSION: This technique allows an anatomic reattachment of distal biceps tendon at the radial tuberosity providing full functional recovery with low complication rate. PMID:25133147

  5. Influence of the large-small split effect on strategy choice in complex subtraction.

    PubMed

    Xiang, Yan Hui; Wu, Hao; Shang, Rui Hong; Chao, Xiaomei; Ren, Ting Ting; Zheng, Li Ling; Mo, Lei

    2018-04-01

    Two main theories have been used to explain the arithmetic split effect: decision-making process theory and strategy choice theory. Using the inequality paradigm, previous studies have confirmed that individuals tend to adopt a plausibility-checking strategy and a whole-calculation strategy to solve large and small split problems in complex addition arithmetic, respectively. This supports strategy choice theory, but it is unknown whether this theory also explains performance in solving different split problems in complex subtraction arithmetic. This study used small, intermediate and large split sizes, with each split condition being further divided into problems requiring and not requiring borrowing. The reaction times (RTs) for large and intermediate splits were significantly shorter than those for small splits, while accuracy was significantly higher for large and middle splits than for small splits, reflecting no speed-accuracy trade-off. Further, RTs and accuracy differed significantly between the borrow and no-borrow conditions only for small splits. This study indicates that strategy choice theory is suitable to explain the split effect in complex subtraction arithmetic. That is, individuals tend to choose the plausibility-checking strategy or the whole-calculation strategy according to the split size. © 2016 International Union of Psychological Science.

  6. StackSplit - a plugin for multi-event shear wave splitting analyses in SplitLab

    NASA Astrophysics Data System (ADS)

    Grund, Michael

    2017-08-01

    SplitLab is a powerful and widely used tool for analysing seismological shear wave splitting of single event measurements. However, in many cases, especially temporary station deployments close to the noisy seaside, ocean bottom or for recordings affected by strong anthropogenic noise, only multi-event approaches provide stable and reliable splitting results. In order to extend the original SplitLab environment for such analyses, I present the StackSplit plugin that can easily be implemented within the well accepted main program. StackSplit grants easy access to several different analysis approaches within SplitLab, including a new multiple waveform based inversion method as well as the most established standard stacking procedures. The possibility to switch between different analysis approaches at any time allows the user for the most flexible processing of individual multi-event splitting measurements for a single recording station. Besides the provided functions of the plugin, no other external program is needed for the multi-event analyses since StackSplit performs within the available SplitLab structure which is based on MATLAB. The effectiveness and use of this plugin is demonstrated with data examples of a long running seismological recording station in Finland.

  7. Implementation and value of using a split-plot reader design in a study of digital breast tomosynthesis in a breast cancer assessment clinic

    NASA Astrophysics Data System (ADS)

    Mall, Suneeta; Brennan, Patrick C.; Mello-Thoms, Claudia

    2015-03-01

    The rapid evolution in medical imaging has led to an increased number of recurrent trials, primarily to ensure that the efficacy of new imaging techniques is known. The cost associated with time and resources in conducting such trials is usually high. The recruitment of participants, in a medium to large reader study, is often very challenging as the demanding number of cases discourages involvement with the trial. We aim to evaluate the efficacy of Digital Breast Tomosynthesis (DBT) in a recall assessment clinic in Australia in a prospective multi-reader-multi-case (MRMC) trial. Conducting such a study with the more commonly used fully crossed MRMC study design would require more cases and more cases read per reader, which was not viable in our setting. With an aim to perform a cost effective yet statistically efficient clinical trial, we evaluated alternative study designs, particularly the alternative split-plot MRMC study design and compared and contrasted it with more commonly used fully crossed MRMC study design. Our results suggest that `split-plot', an alternative MRMC study design, could be very beneficial for medium to large clinical trials and the cost associated with conducting such trials can be greatly reduced without adversely effecting the variance of the study. We have also noted an inverse dependency between number of required readers and cases to achieve a target variance. This suggests that split-plot could also be very beneficial for studies that focus on cases that are hard to procure or readers that are hard to recruit. We believe that our results may be relevant to other researchers seeking to design a medium to large clinical trials.

  8. Negative pressure wound therapy, staged excision and definitive closure with split-thickness skin graft for axillary hidradenitis suppurativa: a retrospective study.

    PubMed

    Pearce, F B; Richardson, K A

    2017-01-02

    Bilateral axillary hidradenitis is a chronic, suppurative, and scarring disease that is most effectively treated by complete excision of all hair-bearing tissues. We assessed our staged procedure for excision and placement of a split-thickness skin graft for bilateral axillary hidradenitis in terms of costs, outcomes, and timing of excision. An IRB approved retrospective case analysis was performed on patients that underwent bilateral axillary hidradenitis skin excision with eventual placement of split-thickness skin grafting using the current LSUHSC/University Health hidradenitis surgical treatment protocol. Using ICD-9 codes (705.83) and CPT codes (11041, 11042, 11451, 11600, 11601, 11602, 11603, 11604) we reviewed cases performed at our institution from 1 January 2008 to 24 Febuary 2014 and we selected patients based on bilateral axillary involvement (alone) and >1 year history of active disease. Patients were excluded if resection of tissue encompassed regions outside of the immediately adjacent axillary. A total of seven patients matching criteria for bilateral axillary hidradenitis were selected for analysis. Clinical course, cost and surgical techniques were assessed. Of the seven patients, six required admission throughout their treatment due to lack of funding making use of negative pressure wound therapy at home not possible. These patients stayed an average of 10 days with a mean hospital charge of $35,178 and a mean hospital provider charge of $10,019. No recurrence was demonstrated. All patients attained full range of motion, post grafting. No patient required a further operation due to graft failure. Split-thickness skin grafting without use of bilayer dermal regenerative templates yielded definitive results with acceptable cosmesis and functionality, without the added cost of treatments such as a bilayer dermal regenerative template.

  9. Combined laparoscopic and vaginal cervicovaginal reconstruction using split thickness skin graft in patients with congenital atresia of cervix.

    PubMed

    Zhang, Xuyin; Han, Tiantian; Ding, Jingxin; Hua, Keqin

    2015-01-01

    The aim of this study was to introduce a new technique which is combined laparoscopic and vaginal cervicovaginal reconstruction using split thickness skin graft in patients with congenital atresia of cervix and to evaluate the feasibility and the safety of it. This is a prospective observational study of 10 patients with congenital atresia of cervix who underwent combined laparoscopic and vaginal cervicovaginal reconstruction using split thickness skin graft for cervicovaginal reconstruction from February 2013 to August 2014 in our hospital. All of the surgical procedures were carried out by the same operation team. Patient data were collected including operating time, estimated blood loss, hospital stay post-surgery, complications, total cost, and median vaginal length at 3 month, resumption of menstruation, vaginal stenosis and stricture of the cervix postoperatively. The operative procedure lasted 237±46 (175-380) min. The estimated blood loss was 160±76 (50-300) ml. The hospital stay post-surgery was 12±2 (9-18) days. None of the patients had complications or required a blood transfusion. The mean total cost was $3352±1025. The average vaginal length at 3 month was 8.3±1.1 (8-10) cm. All patients had resumption of menstruation. The patients were followed for a mean of 5±2 (1-10) months. Cervical or vaginal stenosis did not occur in any of the patients. Our experiences of combined laparoscopic and vaginal cervicovaginal reconstruction using split thickness skin graft in10 patients with congenital atresia of cervix were positive, with successful results and without complications, and cervical or vaginal stenosis.

  10. Combined laparoscopic and vaginal cervicovaginal reconstruction using split thickness skin graft in patients with congenital atresia of cervix

    PubMed Central

    Zhang, Xuyin; Han, Tiantian; Ding, Jingxin; Hua, Keqin

    2015-01-01

    Objective: The aim of this study was to introduce a new technique which is combined laparoscopic and vaginal cervicovaginal reconstruction using split thickness skin graft in patients with congenital atresia of cervix and to evaluate the feasibility and the safety of it. Methods: This is a prospective observational study of 10 patients with congenital atresia of cervix who underwent combined laparoscopic and vaginal cervicovaginal reconstruction using split thickness skin graft for cervicovaginal reconstruction from February 2013 to August 2014 in our hospital. All of the surgical procedures were carried out by the same operation team. Patient data were collected including operating time, estimated blood loss, hospital stay post-surgery, complications, total cost, and median vaginal length at 3 month, resumption of menstruation, vaginal stenosis and stricture of the cervix postoperatively. Results: The operative procedure lasted 237±46 (175-380) min. The estimated blood loss was 160±76 (50-300) ml. The hospital stay post-surgery was 12±2 (9-18) days. None of the patients had complications or required a blood transfusion. The mean total cost was $3352±1025. The average vaginal length at 3 month was 8.3±1.1 (8-10) cm. All patients had resumption of menstruation. The patients were followed for a mean of 5±2 (1-10) months. Cervical or vaginal stenosis did not occur in any of the patients. Conclusions: Our experiences of combined laparoscopic and vaginal cervicovaginal reconstruction using split thickness skin graft in10 patients with congenital atresia of cervix were positive, with successful results and without complications, and cervical or vaginal stenosis. PMID:26309703

  11. Multimodal Imaging of Photoreceptor Structure in Choroideremia

    PubMed Central

    Johnson, Ryan D.; Williams, Vesper; Summerfelt, Phyllis; Dubra, Alfredo; Weinberg, David V.; Stepien, Kimberly E.; Fishman, Gerald A.; Carroll, Joseph

    2016-01-01

    Purpose Choroideremia is a progressive X-linked recessive dystrophy, characterized by degeneration of the retinal pigment epithelium (RPE), choroid, choriocapillaris, and photoreceptors. We examined photoreceptor structure in a series of subjects with choroideremia with particular attention to areas bordering atrophic lesions. Methods Twelve males with clinically-diagnosed choroideremia and confirmed hemizygous mutations in the CHM gene were examined. High-resolution images of the retina were obtained using spectral domain optical coherence tomography (SD-OCT) and both confocal and non-confocal split-detector adaptive optics scanning light ophthalmoscope (AOSLO) techniques. Results Eleven CHM gene mutations (3 novel) were identified; three subjects had the same mutation and one subject had two mutations. SD-OCT findings included interdigitation zone (IZ) attenuation or loss in 10/12 subjects, often in areas with intact ellipsoid zones; RPE thinning in all subjects; interlaminar bridges in the imaged areas of 10/12 subjects; and outer retinal tubulations (ORTs) in 10/12 subjects. Only split-detector AOSLO could reliably resolve cones near lesion borders, and such cones were abnormally heterogeneous in morphology, diameter and density. On split-detector imaging, the cone mosaic terminated sharply at lesion borders in 5/5 cases examined. Split-detector imaging detected remnant cone inner segments within ORTs, which were generally contiguous with a central patch of preserved retina. Conclusions Early IZ dropout and RPE thinning on SD-OCT are consistent with previously published results. Evidence of remnant cone inner segments within ORTs and the continuity of the ORTs with preserved retina suggests that these may represent an intermediate state of retinal degeneration prior to complete atrophy. Taken together, these results supports a model of choroideremia in which the RPE degenerates before photoreceptors. PMID:27936069

  12. Series length used during trend analysis affects sensitivity to changes in progression rate in the ocular hypertension treatment study.

    PubMed

    Gardiner, Stuart K; Demirel, Shaban; De Moraes, Carlos Gustavo; Liebmann, Jeffrey M; Cioffi, George A; Ritch, Robert; Gordon, Mae O; Kass, Michael A

    2013-02-15

    Trend analysis techniques to detect glaucomatous progression typically assume a constant rate of change. This study uses data from the Ocular Hypertension Treatment Study to assess whether this assumption decreases sensitivity to changes in progression rate, by including earlier periods of stability. Series of visual fields (mean 24 per eye) completed at 6-month intervals from participants randomized initially to observation were split into subseries before and after the initiation of treatment (the "split-point"). The mean deviation rate of change (MDR) was derived using these entire subseries, and using only the window length (W) tests nearest the split-point, for different window lengths of W tests. A generalized estimating equation model was used to detect changes in MDR occurring at the split-point. Using shortened subseries with W = 7 tests, the MDR slowed by 0.142 dB/y upon initiation of treatment (P < 0.001), and the proportion of eyes showing "rapid deterioration" (MDR <-0.5 dB/y with P < 5%) decreased from 11.8% to 6.5% (P < 0.001). Using the entire sequence, no significant change in MDR was detected (P = 0.796), and there was no change in the proportion of eyes progressing (P = 0.084). Window lengths 6 ≤ W ≤ 9 produced similar benefits. Event analysis revealed a beneficial treatment effect in this dataset. This effect was not detected by linear trend analysis applied to entire series, but was detected when using shorter subseries of length between six and nine fields. Using linear trend analysis on the entire field sequence may not be optimal for detecting and monitoring progression. Nonlinear analyses may be needed for long series of fields. (ClinicalTrials.gov number, NCT00000125.).

  13. Shear Wave Splitting analysis of borehole microseismic reveals weak azimuthal anisotropy hidden behind strong VTI fabric of Lower Paleozoic shales in northern Poland

    NASA Astrophysics Data System (ADS)

    Gajek, Wojciech; Verdon, James; Malinowski, Michał; Trojanowski, Jacek

    2017-04-01

    Azimuthal anisotropy plays a key-role in hydraulic fracturing experiments, since it provides information on stress orientation and pre-existing fracture system presence. The Lower Paleozoic shale plays in northern Poland are characterized by a strong (15-18%) Vertical Transverse Isotropy (VTI) fabric which dominates weak azimuthal anisotropy being of order of 1-2%. A shear wave travelling in the subsurface after entering an anisotropic medium splits into two orthogonally polarized waves travelling with different velocities. Splitting parameters which can be assessed using a microseismic array are polarization of the fast shear wave and time delay between two modes. Polarization of the fast wave characterizes the anisotropic system on the wave path while the time delay is proportional to the magnitude of anisotropy. We employ Shear Wave Splitting (SWS) technique using a borehole microseismic dataset collected during a hydraulic stimulation treatment located in northern Poland, to image fracture strike masked by a strong VTI signature. During the inversion part, the VTI background parameters were kept constant using information from 3D seismic (VTI model used for pre-stack depth migration). Obtained fracture azimuths averaged over fracturing stages are consistent with the available XRMI imager logs from the nearby vertical well, however they are different from the large-scale maximum stress direction (by 40-45 degrees). Inverted Hudson's crack density (ca. 2%) are compatible with the low shear-wave anisotropy observed in the cross-dipole sonic logs (1-2%). This work has been funded by the Polish National Centre for Research and Development within the Blue Gas project (No BG2/SHALEMECH/14). Data were provided by the PGNiG SA. Collaboration with University of Bristol was supported within TIDES COST Action ES1401.

  14. Significant seismic anisotropy beneath southern Tibet inferred from splitting of direct S-waves

    NASA Astrophysics Data System (ADS)

    Singh, Arun; Eken, Tuna; Mohanty, Debasis D.; Saikia, Dipankar; Singh, Chandrani; Ravi Kumar, M.

    2016-01-01

    This study presents a total of 12008 shear wave splitting measurements obtained using the reference-station technique applied to direct S-waves from 106 earthquakes recorded at 143 seismic stations of the Hi-CLIMB seismic network. The results reveal significant anisotropy in regions of southern Tibet where null or negligible anisotropy has been hitherto reported from SK(K)S measurements. While the individual fast polarization direction (FPD) at each station are found to be consistent, the splitting time delays (TDs) exhibit deviations particularly at stations located south of the Indus-Tsangpo Suture Zone. The fast polarization directions (FPDs) are oriented (a) NE-SW to E-W to the south of the Indus-Tsangpo Suture Zone (b) NE-SW to ENE-SSW between Bangong-Nujiang Suture Zone and the Indus-Tsangpo Suture Zone (ITSZ) and (c) E-W to the extreme north of the profile. The splitting time delays (δt) vary between 0.45 and 1.3 s south of the ITSZ (<30°N latitude), while they range from 0.9 to 1.4 s north of it. The overall trends are similar to SKS/SKKS results. However, the differences may be due to the not so near vertical paths of direct S waves which may sample the anisotropy in a different way in comparison to SKS waves, or insufficient number of SKS observations. The significant anisotropy (∼ 0.8 s) observed beneath Himalaya reveals a complex deformation pattern in the region and can be best explained by the combined effects of deformation related to shear at the base of the lithosphere and subduction related flows with possible contributions from the crust. Additional measurements obtained using direct S-waves provide new constraints in regions with complex anisotropy.

  15. Multimodal Imaging of Photoreceptor Structure in Choroideremia.

    PubMed

    Sun, Lynn W; Johnson, Ryan D; Williams, Vesper; Summerfelt, Phyllis; Dubra, Alfredo; Weinberg, David V; Stepien, Kimberly E; Fishman, Gerald A; Carroll, Joseph

    2016-01-01

    Choroideremia is a progressive X-linked recessive dystrophy, characterized by degeneration of the retinal pigment epithelium (RPE), choroid, choriocapillaris, and photoreceptors. We examined photoreceptor structure in a series of subjects with choroideremia with particular attention to areas bordering atrophic lesions. Twelve males with clinically-diagnosed choroideremia and confirmed hemizygous mutations in the CHM gene were examined. High-resolution images of the retina were obtained using spectral domain optical coherence tomography (SD-OCT) and both confocal and non-confocal split-detector adaptive optics scanning light ophthalmoscope (AOSLO) techniques. Eleven CHM gene mutations (3 novel) were identified; three subjects had the same mutation and one subject had two mutations. SD-OCT findings included interdigitation zone (IZ) attenuation or loss in 10/12 subjects, often in areas with intact ellipsoid zones; RPE thinning in all subjects; interlaminar bridges in the imaged areas of 10/12 subjects; and outer retinal tubulations (ORTs) in 10/12 subjects. Only split-detector AOSLO could reliably resolve cones near lesion borders, and such cones were abnormally heterogeneous in morphology, diameter and density. On split-detector imaging, the cone mosaic terminated sharply at lesion borders in 5/5 cases examined. Split-detector imaging detected remnant cone inner segments within ORTs, which were generally contiguous with a central patch of preserved retina. Early IZ dropout and RPE thinning on SD-OCT are consistent with previously published results. Evidence of remnant cone inner segments within ORTs and the continuity of the ORTs with preserved retina suggests that these may represent an intermediate state of retinal degeneration prior to complete atrophy. Taken together, these results supports a model of choroideremia in which the RPE degenerates before photoreceptors.

  16. A technique to produce aluminum color bands for avian research

    USGS Publications Warehouse

    Koronkiewicz, T.J.; Paxton, E.H.; Sogge, M.K.

    2005-01-01

    We developed a technique to produce metal (aluminum) color bands, in response to concerns about leg injuries caused by celluloid-plastic color bands applied to Willow Flycatchers (Empidonax traillii). The technique involves color-anodized aluminum bands (unnumbered blanks and federal numbered bands), with auto pin-striping tape and flexible epoxy sealant, to create a variety of solid, half- and triple-split colors. This allows for hundreds of unique, high-contrast color combinations. During six consecutive years of application, these colored metal bands have resisted color fade compared to conventional celluloid-plastic bands, and have reduced leg injuries in the flycatcher. Although not necessarily warranted for all color-banding studies, these metal bands may provide a lower-impact option for studies of species known to be impacted by plastic color bands.

  17. Formation of thin film like assembly of exfoliated C3N4 nanoflakes by solvent non-evaporative method using centrifuge

    NASA Astrophysics Data System (ADS)

    Tejasvi, Ravi; Basu, Suddhasatwa

    2017-12-01

    A simple method for depositing a thin film of nanomaterial on a substrate using centrifugation technique has been developed, whereby solvent evaporation is prevented and solvent reuse is possible. The centrifuge technique of deposition yields uniform, smooth thin film irrespective of substrate surface texture. The deposited TiO2/eC3N4 film studied, through field emission scanning electron microscope, atomic force microscope, and optical surface profilometer, shows variation in surface roughness on the basis of centrifugation speeds. Initially film coverage improves and surface roughness decreases with the increase in rpm of the centrifuge and the surface roughness slightly increases with further increase in rpm. The photoelectrochemical studies of TiO2/eC3N4 films suggest that the centrifuge technique forms better heterojunctions compared to that by spin coating technique leading to enhanced photoelectrochemical water splitting.

  18. [Surgical techniques in liver transplantation].

    PubMed

    Chan, Carlos; Plata-Muñoz, Juan José; Franssen, Bernardo

    2005-01-01

    Liver transplantation (LT) is probably the biggest surgical aggression that a patient can endure. It was considered only as a last option in the era of experimental LT, yet it evolved into the definitive treatment for some types of acute and chronic end stage liver disease. In terms of technique LT is the most complex of all types of transplantations. The surgical procedure in itself is well established and has changed little through time. Liver transplantation owes its improvement to better and more systematic anesthetic procedures and to perioperative care more than being due to improvement of the surgical technique. The first surgical procedure was described by Thomas Starzl in 1969. His initial work has been strengthened with the development of venous bypass, the refinement in vascular and biliary reconstruction technique and the development of the split liver. Up to date technical aspects of orthotopic liver transplantation are described in the present article.

  19. On-demand acoustic droplet splitting and steering in a disposable microfluidic chip.

    PubMed

    Park, Jinsoo; Jung, Jin Ho; Park, Kwangseok; Destgeer, Ghulam; Ahmed, Husnain; Ahmad, Raheel; Sung, Hyung Jin

    2018-01-30

    On-chip droplet splitting is one of the fundamental droplet-based microfluidic unit operations to control droplet volume after production and increase operational capability, flexibility, and throughput. Various droplet splitting methods have been proposed, and among them the acoustic droplet splitting method is promising because of its label-free operation without any physical or thermal damage to droplets. Previous acoustic droplet splitting methods faced several limitations: first, they employed a cross-type acoustofluidic device that precluded multichannel droplet splitting; second, they required irreversible bonding between a piezoelectric substrate and a microfluidic chip, such that the fluidic chip was not replaceable. Here, we present a parallel-type acoustofluidic device with a disposable microfluidic chip to address the limitations of previous acoustic droplet splitting devices. In the proposed device, an acoustic field is applied in the direction opposite to the flow direction to achieve multichannel droplet splitting and steering. A disposable polydimethylsiloxane microfluidic chip is employed in the developed device, thereby removing the need for permanent bonding and improving the flexibility of the droplet microfluidic device. We experimentally demonstrated on-demand acoustic droplet bi-splitting and steering with precise control over the droplet splitting ratio, and we investigated the underlying physical mechanisms of droplet splitting and steering based on Laplace pressure and ray acoustics analyses, respectively. We also demonstrated droplet tri-splitting to prove the feasibility of multichannel droplet splitting. The proposed on-demand acoustic droplet splitting device enables on-chip droplet volume control in various droplet-based microfluidic applications.

  20. Two dimensional exciton polaritons in microcavities with embedded quantum wires

    NASA Astrophysics Data System (ADS)

    Kavokin, A. V.; Ivchenko, E. L.; Vladimirova, M. R.; Kaliteevski, M. A.; Goupalov, S. V.

    1998-02-01

    Optical anisotropy of the periodical array of quantum wires embedded in a semiconductor microcavity is shown to result in polarization-dependent vacuum-field Rabi-splitting and a triple-anticrossing shape of the exciton-polariton dispersion curves. Both effects originate from the resonant diffraction of light at the grating of quantum wires. The calculation has been done within the nonlocal dielectric response theory and using the 4 × 4 transfer matrix technique.

  1. Range safety signal propagation through the SRM exhaust plume of the space shuttle

    NASA Technical Reports Server (NTRS)

    Boynton, F. P.; Davies, A. R.; Rajasekhar, P. S.; Thompson, J. A.

    1977-01-01

    Theoretical predictions of plume interference for the space shuttle range safety system by solid rocket booster exhaust plumes are reported. The signal propagation was calculated using a split operator technique based upon the Fresnel-Kirchoff integral, using fast Fourier transforms to evaluate the convolution and treating the plume as a series of absorbing and phase-changing screens. Talanov's lens transformation was applied to reduce aliasing problems caused by ray divergence.

  2. Behavioral Modeling and Characterization of Nonlinear Operation in RF and Microwave Systems

    DTIC Science & Technology

    2005-01-01

    the model further reinforces the intuition gained by employing this modeling technique. 84 Chapter 5 Remote Characterization of RF Devices 5.1...was used to extract the power series coefficients, 21 dBm. This further reinforces the conclusion that the nonlinear coefficients should be extracted...are becoming important. The fit of the odd-ordered model reinforces this hypothesis since the phase component of the fit roughly splits the

  3. Time Dependent Studies of Reactive Shocks in the Gas Phase

    DTIC Science & Technology

    1978-11-16

    which takes advantsge of time-stop splitting. The fluid dynamics time integration is performed by an explicit two step predictor - corrector technique...Nava Reearh l~oraoryARIA A WORK UNIT NUMBERS NasahRaington MC, raor 2037 NR Problem (1101-16Washngto, !) C , 2i176ONR Project RR024.02.41 Office of... self -consistently on their own characteristic time-scaies using the flux-corrected transport and selected asymptotic meothods, respectively. Results are

  4. Method and apparatus for optical communication by frequency modulation

    DOEpatents

    Priatko, Gordon J.

    1988-01-01

    Laser optical communication according to this invention is carried out by producing multi-frequency laser beams having different frequencies, splitting one or more of these constituent beams into reference and signal beams, encoding information on the signal beams by frequency modulation and detecting the encoded information by heterodyne techniques. Much more information can be transmitted over optical paths according to the present invention than with the use of only one path as done previously.

  5. Rapid Mars transits with exhaust-modulated plasma propulsion

    NASA Technical Reports Server (NTRS)

    Chang-Diaz, Franklin R.; Braden, Ellen; Johnson, Ivan; Hsu, Michael M.; Yang, Tien Fang

    1995-01-01

    The operational characteristics of the Exhaust-Modulated Plasma Rocket are described. Four basic human and robotic mission scenarios to Mars are analyzed using numerical optimization techniques at variable specific impulse and constant power. The device is well suited for 'split-sprint' missions, allowing fast, one-way low-payload human transits of 90 to 104 days, as well as slower, 180-day, high-payload robotic precursor flights. Abort capabilities, essential for human missions, are also explored.

  6. Common Aperture Techniques for Imaging Electro-Optical Sensors (CATIES).

    DTIC Science & Technology

    1980-02-01

    milliradians ) at the 5.33:1 zoom point. The zoom optics contain five elements with two moveable air -spaced doublets for accomplishing the zoom function...included in the electrical and optical design but due to funding limitations, system safety requirements during the testing phase and lack of long-term...determined during the system testing phase to be conducted by the Air Force. Limited electronic signal processing (split screen and video mix) was

  7. Nonequilibrium flow computations. 1: An analysis of numerical formulations of conservation laws

    NASA Technical Reports Server (NTRS)

    Liu, Yen; Vinokur, Marcel

    1988-01-01

    Modern numerical techniques employing properties of flux Jacobian matrices are extended to general, nonequilibrium flows. Generalizations of the Beam-Warming scheme, Steger-Warming and van Leer Flux-vector splittings, and Roe's approximate Riemann solver are presented for 3-D, time-varying grids. The analysis is based on a thermodynamic model that includes the most general thermal and chemical nonequilibrium flow of an arbitrary gas. Various special cases are also discussed.

  8. CrossTalk: The Journal of Defense Software Engineering. Volume 27, Number 1, January/February 2014

    DTIC Science & Technology

    2014-02-01

    deficit in trustworthiness and will permit analysis on how this deficit needs to be overcome. This analysis will help identify adaptations that are...approaches to trustworthy analysis split into two categories: product-based and process-based. Product-based techniques [9] identify factors that...Criticalities may also be assigned to decompositions and contributions. 5. Evaluation and analysis : in this task the propagation rules of the NFR

  9. EM Propagation & Atmospheric Effects Assessment

    DTIC Science & Technology

    2008-09-30

    The split-step Fourier parabolic equation ( SSPE ) algorithm provides the complex amplitude and phase (group delay) of the continuous wave (CW) signal...the APM is based on the SSPE , we are implementing the more efficient Fourier synthesis technique to determine the transfer function. To this end a...needed in order to sample H(f) via the SSPE , and indeed with the proper parameters chosen, the two pulses can be resolved in the time window shown in

  10. Observation of the hyperfine spectrum of antihydrogen.

    PubMed

    Ahmadi, M; Alves, B X R; Baker, C J; Bertsche, W; Butler, E; Capra, A; Carruth, C; Cesar, C L; Charlton, M; Cohen, S; Collister, R; Eriksson, S; Evans, A; Evetts, N; Fajans, J; Friesen, T; Fujiwara, M C; Gill, D R; Gutierrez, A; Hangst, J S; Hardy, W N; Hayden, M E; Isaac, C A; Ishida, A; Johnson, M A; Jones, S A; Jonsell, S; Kurchaninov, L; Madsen, N; Mathers, M; Maxwell, D; McKenna, J T K; Menary, S; Michan, J M; Momose, T; Munich, J J; Nolan, P; Olchanski, K; Olin, A; Pusa, P; Rasmussen, C Ø; Robicheaux, F; Sacramento, R L; Sameed, M; Sarid, E; Silveira, D M; Stracka, S; Stutter, G; So, C; Tharp, T D; Thompson, J E; Thompson, R I; van der Werf, D P; Wurtele, J S

    2017-08-02

    The observation of hyperfine structure in atomic hydrogen by Rabi and co-workers and the measurement of the zero-field ground-state splitting at the level of seven parts in 10 13 are important achievements of mid-twentieth-century physics. The work that led to these achievements also provided the first evidence for the anomalous magnetic moment of the electron, inspired Schwinger's relativistic theory of quantum electrodynamics and gave rise to the hydrogen maser, which is a critical component of modern navigation, geo-positioning and very-long-baseline interferometry systems. Research at the Antiproton Decelerator at CERN by the ALPHA collaboration extends these enquiries into the antimatter sector. Recently, tools have been developed that enable studies of the hyperfine structure of antihydrogen-the antimatter counterpart of hydrogen. The goal of such studies is to search for any differences that might exist between this archetypal pair of atoms, and thereby to test the fundamental principles on which quantum field theory is constructed. Magnetic trapping of antihydrogen atoms provides a means of studying them by combining electromagnetic interaction with detection techniques that are unique to antimatter. Here we report the results of a microwave spectroscopy experiment in which we probe the response of antihydrogen over a controlled range of frequencies. The data reveal clear and distinct signatures of two allowed transitions, from which we obtain a direct, magnetic-field-independent measurement of the hyperfine splitting. From a set of trials involving 194 detected atoms, we determine a splitting of 1,420.4 ± 0.5 megahertz, consistent with expectations for atomic hydrogen at the level of four parts in 10 4 . This observation of the detailed behaviour of a quantum transition in an atom of antihydrogen exemplifies tests of fundamental symmetries such as charge-parity-time in antimatter, and the techniques developed here will enable more-precise such tests.

  11. SEISMIC ANISOTROPY ANALYSIS IN THE VICTORIA LAND REGION (ANTARCTICA)

    NASA Astrophysics Data System (ADS)

    Salimbeni, S.; Pondrelli, S.; Danesi, S.; Morelli, A.

    2009-12-01

    We present here shear wave splitting results obtained from analysis of core refracted teleseismic phases in the Victoria Land region (Antarctica). We used data belonging to permanent and temporary stations in the area. The temporary stations are located around the David Glaciers and installation is part of two expeditions inside the Italian National Antarctic program (PNRA, Programma Nazionale di Ricerche in Antartide). The network was composed by 8 seismic stations, located on rocky outcrops around the glacier, and has been active from November 2003 to February 2004, and from November 2005 to February 2006. One of this (STAR) became permanent on 2004 and data until 2007 are analyzed. We use eigenvalue technique of Silver and Chan (1991) to linearize the rotated and shifted shear wave particle motions and determine the best splitting parameters. Scattered distribution of single shear-wave measurements is obtained. Null measurements follow the same distribution. Average measurements show clearly that the main anisotropy direction is NE-SW, accordingly with previous measurements obtained around this zone. Only two stations, OHG and STAR, have a different orientation and a N-S and NNW-SSE main directions are obtained respectively. The distribution of single shear-wave splitting measurements evidenced periodicity respect the back-azimuth of the events analyzed, therefore a possible two layers anisotropic structures could be supposed. To test this hypothesis we used the Menke and Levin (2003) code that allow to model waveforms using a cross convolution technique in one and two layer's cases. Significant improvements of the misfit in the double layer case allow choosing this more complex model. The one layer structure is the best for permanent stations TNV and VNDA with directions and delay time accordingly with average measurements. The double layer models fit better the data on stations STAR, located near the coast, and OHG located inland, and show in both cases the same contribution of the anisotropy.

  12. Observation of the hyperfine spectrum of antihydrogen

    NASA Astrophysics Data System (ADS)

    Ahmadi, M.; Alves, B. X. R.; Baker, C. J.; Bertsche, W.; Butler, E.; Capra, A.; Carruth, C.; Cesar, C. L.; Charlton, M.; Cohen, S.; Collister, R.; Eriksson, S.; Evans, A.; Evetts, N.; Fajans, J.; Friesen, T.; Fujiwara, M. C.; Gill, D. R.; Gutierrez, A.; Hangst, J. S.; Hardy, W. N.; Hayden, M. E.; Isaac, C. A.; Ishida, A.; Johnson, M. A.; Jones, S. A.; Jonsell, S.; Kurchaninov, L.; Madsen, N.; Mathers, M.; Maxwell, D.; McKenna, J. T. K.; Menary, S.; Michan, J. M.; Momose, T.; Munich, J. J.; Nolan, P.; Olchanski, K.; Olin, A.; Pusa, P.; Rasmussen, C. Ø.; Robicheaux, F.; Sacramento, R. L.; Sameed, M.; Sarid, E.; Silveira, D. M.; Stracka, S.; Stutter, G.; So, C.; Tharp, T. D.; Thompson, J. E.; Thompson, R. I.; van der Werf, D. P.; Wurtele, J. S.

    2017-08-01

    The observation of hyperfine structure in atomic hydrogen by Rabi and co-workers and the measurement of the zero-field ground-state splitting at the level of seven parts in 1013 are important achievements of mid-twentieth-century physics. The work that led to these achievements also provided the first evidence for the anomalous magnetic moment of the electron, inspired Schwinger’s relativistic theory of quantum electrodynamics and gave rise to the hydrogen maser, which is a critical component of modern navigation, geo-positioning and very-long-baseline interferometry systems. Research at the Antiproton Decelerator at CERN by the ALPHA collaboration extends these enquiries into the antimatter sector. Recently, tools have been developed that enable studies of the hyperfine structure of antihydrogen—the antimatter counterpart of hydrogen. The goal of such studies is to search for any differences that might exist between this archetypal pair of atoms, and thereby to test the fundamental principles on which quantum field theory is constructed. Magnetic trapping of antihydrogen atoms provides a means of studying them by combining electromagnetic interaction with detection techniques that are unique to antimatter. Here we report the results of a microwave spectroscopy experiment in which we probe the response of antihydrogen over a controlled range of frequencies. The data reveal clear and distinct signatures of two allowed transitions, from which we obtain a direct, magnetic-field-independent measurement of the hyperfine splitting. From a set of trials involving 194 detected atoms, we determine a splitting of 1,420.4 ± 0.5 megahertz, consistent with expectations for atomic hydrogen at the level of four parts in 104. This observation of the detailed behaviour of a quantum transition in an atom of antihydrogen exemplifies tests of fundamental symmetries such as charge-parity-time in antimatter, and the techniques developed here will enable more-precise such tests.

  13. Using histograms to introduce randomization in the generation of ensembles of decision trees

    DOEpatents

    Kamath, Chandrika; Cantu-Paz, Erick; Littau, David

    2005-02-22

    A system for decision tree ensembles that includes a module to read the data, a module to create a histogram, a module to evaluate a potential split according to some criterion using the histogram, a module to select a split point randomly in an interval around the best split, a module to split the data, and a module to combine multiple decision trees in ensembles. The decision tree method includes the steps of reading the data; creating a histogram; evaluating a potential split according to some criterion using the histogram, selecting a split point randomly in an interval around the best split, splitting the data, and combining multiple decision trees in ensembles.

  14. Fracture patterns after bilateral sagittal split osteotomy of the mandibular ramus according to the Obwegeser/Dal Pont and Hunsuck/Epker modifications.

    PubMed

    Möhlhenrich, Stephan Christian; Kniha, Kristian; Peters, Florian; Ayoub, Nassim; Goloborodko, Evgeny; Hölzle, Frank; Fritz, Ulrike; Modabber, Ali

    2017-05-01

    The aim of this study was to compare the fracture patterns after sagittal split osteotomy according to Obwegeser/Dal Pont (ODP) and Hunsuck/Epker (HE), as well as to investigate the relationship between lateral bone cut ending or angle and the incidence of unfavorable/bad splits. Postoperative cone-beam computed tomograms of 124 splits according to ODP and 60 according to HE were analyzed. ODP led to 75.8% and HE led to 60% lingual fractures with mandibular foramen contact. Horizontal fractures were found in 9.7% and 6.7%, respectively, and unfavorable/bad splits were found in 11.3% and 10%, respectively. The lateral osteotomy angle was 106.22° (SD 12.03)° for bad splits and 106.6° (SD 13.12)° for favorable splits. Correlations were found between favorable fracture patterns and split modifications and between buccal ending of the lateral bone cut and bad splits (p < 0.001). No relationship was observed between split modifications (p = 0.792) or the osteotomy angle (p = 0.937) and the incidence of unfavorable/bad splits. Split modifications had no influence on the incidence of unfavorable/bad splits, but the buccal ending of the lateral bone cut did have an influence. More lingual fractures with mandibular foramen contact are expected with the ODP modification. The osteotomy angle did not differ between favorable and bad splits. Copyright © 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  15. Clinical application of calculated split renal volume using computed tomography-based renal volumetry after partial nephrectomy: Correlation with technetium-99m dimercaptosuccinic acid renal scan data.

    PubMed

    Lee, Chan Ho; Park, Young Joo; Ku, Ja Yoon; Ha, Hong Koo

    2017-06-01

    To evaluate the clinical application of computed tomography-based measurement of renal cortical volume and split renal volume as a single tool to assess the anatomy and renal function in patients with renal tumors before and after partial nephrectomy, and to compare the findings with technetium-99m dimercaptosuccinic acid renal scan. The data of 51 patients with a unilateral renal tumor managed by partial nephrectomy were retrospectively analyzed. The renal cortical volume of tumor-bearing and contralateral kidneys was measured using ImageJ software. Split estimated glomerular filtration rate and split renal volume calculated using this renal cortical volume were compared with the split renal function measured with technetium-99m dimercaptosuccinic acid renal scan. A strong correlation between split renal function and split renal volume of the tumor-bearing kidney was observed before and after surgery (r = 0.89, P < 0.001 and r = 0.94, P < 0.001). The preoperative and postoperative split estimated glomerular filtration rate of the operated kidney showed a moderate correlation with split renal function (r = 0.39, P = 0.004 and r = 0.49, P < 0.001). The correlation between reductions in split renal function and split renal volume of the operated kidney (r = 0.87, P < 0.001) was stronger than that between split renal function and percent reduction in split estimated glomerular filtration rate (r = 0.64, P < 0.001). The split renal volume calculated using computed tomography-based renal volumetry had a strong correlation with the split renal function measured using technetium-99m dimercaptosuccinic acid renal scan. Computed tomography-based split renal volume measurement before and after partial nephrectomy can be used as a single modality for anatomical and functional assessment of the tumor-bearing kidney. © 2017 The Japanese Urological Association.

  16. An experimental investigation of bubble splitting through multiple bifurcations

    NASA Astrophysics Data System (ADS)

    Bull, Joseph L.; Eshpuniyani, Brijesh; Fowlkes, J. Brian

    2004-11-01

    A bench top vascular bifurcation model is used to investigate the splitting of long bubbles in a series of liquid-filled bifurcations. These experiments are motivated by a gas embolotherapy technique for the potential treatment of cancer by using gas emboli to infarct tumors. The gas bubbles originate as perfluorocarbon droplets that are small enough to pass through capillaries and are injected into the bloodstream. Low intensity ultrasound is used to track their motion, and they are vaporized at the desired location for treatment via high intensity ultrasound to produce gas bubbles whose volumes are approximately 125 to 150 times the droplet volume. Achieving complete tumor necrosis requires infarction of most of the tumor. Understanding the transport and splitting of the gas bubbles, which can be long enough to extend through more than one bifurcation, is necessary to design delivery strategies. The current experiments investigate the behavior of a bubble as it passes through a series of two geometrically symmetric bifurcations, for different values of effective Bond number, which depends on gravity and the positioning of the bifurcation, capillary number, and bubble volume. The experiments are designed to match the Reynolds, Bond and capillary numbers to the physiological values for arterioles, and to provide guidance in achieving uniform tumor infarction. This work is supported by NSF grant BES-0301278 and NIH grant EB003541-01.

  17. Quadratic String Method for Locating Instantons in Tunneling Splitting Calculations.

    PubMed

    Cvitaš, Marko T

    2018-03-13

    The ring-polymer instanton (RPI) method is an efficient technique for calculating approximate tunneling splittings in high-dimensional molecular systems. In the RPI method, tunneling splitting is evaluated from the properties of the minimum action path (MAP) connecting the symmetric wells, whereby the extensive sampling of the full potential energy surface of the exact quantum-dynamics methods is avoided. Nevertheless, the search for the MAP is usually the most time-consuming step in the standard numerical procedures. Recently, nudged elastic band (NEB) and string methods, originaly developed for locating minimum energy paths (MEPs), were adapted for the purpose of MAP finding with great efficiency gains [ J. Chem. Theory Comput. 2016 , 12 , 787 ]. In this work, we develop a new quadratic string method for locating instantons. The Euclidean action is minimized by propagating the initial guess (a path connecting two wells) over the quadratic potential energy surface approximated by means of updated Hessians. This allows the algorithm to take many minimization steps between the potential/gradient calls with further reductions in the computational effort, exploiting the smoothness of potential energy surface. The approach is general, as it uses Cartesian coordinates, and widely applicable, with computational effort of finding the instanton usually lower than that of determining the MEP. It can be combined with expensive potential energy surfaces or on-the-fly electronic-structure methods to explore a wide variety of molecular systems.

  18. An experimental study of fuel injection strategies in CAI gasoline engine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hunicz, J.; Kordos, P.

    2011-01-15

    Combustion of gasoline in a direct injection controlled auto-ignition (CAI) single-cylinder research engine was studied. CAI operation was achieved with the use of the negative valve overlap (NVO) technique and internal exhaust gas re-circulation (EGR). Experiments were performed at single injection and split injection, where some amount of fuel was injected close to top dead centre (TDC) during NVO interval, and the second injection was applied with variable timing. Additionally, combustion at variable fuel-rail pressure was examined. Investigation showed that at fuel injection into recompressed exhaust fuel reforming took place. This process was identified via an analysis of the exhaust-fuelmore » mixture composition after NVO interval. It was found that at single fuel injection in NVO phase, its advance determined the heat release rate and auto-ignition timing, and had a strong influence on NO{sub X} emission. However, a delay of single injection to intake stroke resulted in deterioration of cycle-to-cycle variability. Application of split injection showed benefits of this strategy versus single injection. Examinations of different fuel mass split ratios and variable second injection timing resulted in further optimisation of mixture formation. At equal share of the fuel mass injected in the first injection during NVO and in the second injection at the beginning of compression, the lowest emission level and cyclic variability improvement were observed. (author)« less

  19. Using the split Hopkinson pressure bar to validate material models.

    PubMed

    Church, Philip; Cornish, Rory; Cullis, Ian; Gould, Peter; Lewtas, Ian

    2014-08-28

    This paper gives a discussion of the use of the split-Hopkinson bar with particular reference to the requirements of materials modelling at QinetiQ. This is to deploy validated material models for numerical simulations that are physically based and have as little characterization overhead as possible. In order to have confidence that the models have a wide range of applicability, this means, at most, characterizing the models at low rate and then validating them at high rate. The split Hopkinson pressure bar (SHPB) is ideal for this purpose. It is also a very useful tool for analysing material behaviour under non-shock wave loading. This means understanding the output of the test and developing techniques for reliable comparison of simulations with SHPB data. For materials other than metals comparison with an output stress v strain curve is not sufficient as the assumptions built into the classical analysis are generally violated. The method described in this paper compares the simulations with as much validation data as can be derived from deployed instrumentation including the raw strain gauge data on the input and output bars, which avoids any assumptions about stress equilibrium. One has to take into account Pochhammer-Chree oscillations and their effect on the specimen and recognize that this is itself also a valuable validation test of the material model. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  20. CT volumetry is superior to nuclear renography for prediction of residual kidney function in living donors.

    PubMed

    Barbas, Andrew S; Li, Yanhong; Zair, Murtuza; Van, Julie A; Famure, Olusegun; Dib, Martin J; Laurence, Jerome M; Kim, S Joseph; Ghanekar, Anand

    2016-09-01

    Living kidney donor evaluation commonly includes nuclear renography to assess split kidney function and computed tomography (CT) scan to evaluate anatomy. To streamline donor workup and minimize exposure to radioisotopes, we sought to assess the feasibility of using proportional kidney volume from CT volumetry in lieu of nuclear renography. We examined the correlation between techniques and assessed their ability to predict residual postoperative kidney function following live donor nephrectomy. In a cohort of 224 live kidney donors, we compared proportional kidney volume derived by CT volumetry with split kidney function derived from nuclear renography and found only modest correlation (left kidney R(2) =26.2%, right kidney R(2) =26.7%). In a subset of 88 live kidney donors with serum creatinine measured 6 months postoperatively, we compared observed estimated glomerular filtration rate (eGFR) at 6 months with predicted eGFR from preoperative imaging. Compared to nuclear renography, CT volumetry more closely approximated actual observed postoperative eGFR for Chronic Kidney Disease Epidemiology Collaboration (J-test: P=.02, Cox-Pesaran test: P=.01) and Mayo formulas (J-test: P=.004, Cox-Pesaran test: P<.001). These observations support the use of CT volumetry for estimation of split kidney function in healthy individuals with normal kidney function and morphology. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Use of split-thickness plantar skin grafts in the management of leg and foot skin defects.

    PubMed

    Liu, Hung-Hui; Chang, Chun-Kai; Huang, Chih-Han; Wu, Jen-Ru; Chen, Chun-Yu; Huang, Dun-Wei; Chu, Tzi-Shiang; Hsu, Kuo-Feng; Wang, Chi-Yu; Chiang, I-Han; Ou, Kuang-Ling; Wang, Chih-Hsin; Dai, Niann-Tzyy; Chen, Shyi-Gen; Tzeng, Yuan-Sheng

    2018-05-24

    The basic principle of donor site selection is to take skin from areas that will heal with minimal scarring while balancing the needs of the recipient site. For skin loss from the lower legs and feet, the most common harvest site for split-thickness skin grafts is the anterior or posterior thigh; grafts from the plantar areas have been mostly used to cover the volar aspect of digits and palms. Between September 2015 and September 2017, 42 patients with areas of skin loss on the legs or feet were treated with plantar skin grafts because of their cosmetic benefits and the convenience of the surgical procedure and postoperative wound care. Our technique of harvesting a single layer of split-thickness skin graft (0.014 in. thick) from a non-weight-bearing area of the foot of the injured leg is simple and provided good functional and cosmetic outcomes at both the donor and recipient sites. All patients were very satisfied with the recovery progress and final results. Therefore, in the management of skin defects in the lower legs or feet that comprise less than 1.5% of the total body surface area, our surgical method is a reliable alternative to anterior or posterior thigh skin grafting. © 2018 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

  2. Meshless Method with Operator Splitting Technique for Transient Nonlinear Bioheat Transfer in Two-Dimensional Skin Tissues

    PubMed Central

    Zhang, Ze-Wei; Wang, Hui; Qin, Qing-Hua

    2015-01-01

    A meshless numerical scheme combining the operator splitting method (OSM), the radial basis function (RBF) interpolation, and the method of fundamental solutions (MFS) is developed for solving transient nonlinear bioheat problems in two-dimensional (2D) skin tissues. In the numerical scheme, the nonlinearity caused by linear and exponential relationships of temperature-dependent blood perfusion rate (TDBPR) is taken into consideration. In the analysis, the OSM is used first to separate the Laplacian operator and the nonlinear source term, and then the second-order time-stepping schemes are employed for approximating two splitting operators to convert the original governing equation into a linear nonhomogeneous Helmholtz-type governing equation (NHGE) at each time step. Subsequently, the RBF interpolation and the MFS involving the fundamental solution of the Laplace equation are respectively employed to obtain approximated particular and homogeneous solutions of the nonhomogeneous Helmholtz-type governing equation. Finally, the full fields consisting of the particular and homogeneous solutions are enforced to fit the NHGE at interpolation points and the boundary conditions at boundary collocations for determining unknowns at each time step. The proposed method is verified by comparison of other methods. Furthermore, the sensitivity of the coefficients in the cases of a linear and an exponential relationship of TDBPR is investigated to reveal their bioheat effect on the skin tissue. PMID:25603180

  3. Meshless method with operator splitting technique for transient nonlinear bioheat transfer in two-dimensional skin tissues.

    PubMed

    Zhang, Ze-Wei; Wang, Hui; Qin, Qing-Hua

    2015-01-16

    A meshless numerical scheme combining the operator splitting method (OSM), the radial basis function (RBF) interpolation, and the method of fundamental solutions (MFS) is developed for solving transient nonlinear bioheat problems in two-dimensional (2D) skin tissues. In the numerical scheme, the nonlinearity caused by linear and exponential relationships of temperature-dependent blood perfusion rate (TDBPR) is taken into consideration. In the analysis, the OSM is used first to separate the Laplacian operator and the nonlinear source term, and then the second-order time-stepping schemes are employed for approximating two splitting operators to convert the original governing equation into a linear nonhomogeneous Helmholtz-type governing equation (NHGE) at each time step. Subsequently, the RBF interpolation and the MFS involving the fundamental solution of the Laplace equation are respectively employed to obtain approximated particular and homogeneous solutions of the nonhomogeneous Helmholtz-type governing equation. Finally, the full fields consisting of the particular and homogeneous solutions are enforced to fit the NHGE at interpolation points and the boundary conditions at boundary collocations for determining unknowns at each time step. The proposed method is verified by comparison of other methods. Furthermore, the sensitivity of the coefficients in the cases of a linear and an exponential relationship of TDBPR is investigated to reveal their bioheat effect on the skin tissue.

  4. Optical signal splitting and chirping device modeling

    NASA Astrophysics Data System (ADS)

    Vinogradova, Irina L.; Andrianova, Anna V.; Meshkov, Ivan K.; Sultanov, Albert Kh.; Abdrakhmanova, Guzel I.; Grakhova, Elizaveta P.; Ishmyarov, Arsen A.; Yantilina, Liliya Z.; Kutlieva, Gulnaz R.

    2017-04-01

    This article examines the devices for optical signal splitting and chirping device modeling. Models with splitting and switching functions are taken into consideration. The described device for optical signal splitting and chirping represents interferential splitter with profiled mixer which provides allocation of correspondent spectral component from ultra wide band frequency diapason, and signal phase shift for aerial array (AA) directive diagram control. This paper proposes modeling for two types of devices for optical signal splitting and chirping: the interference-type optical signal splitting and chirping device and the long-distance-type optical signal splitting and chirping device.

  5. Fee Splitting among General Practitioners: A Cross-Sectional Study in Iran.

    PubMed

    Parsa, Mojtaba; Larijani, Bagher; Aramesh, Kiarash; Nedjat, Saharnaz; Fotouhi, Akbar; Yekaninejad, Mir Saeed; Ebrahimian, Nejatollah; Kandi, Mohamad Jafar

    2016-12-01

    Fee splitting is a process whereby a physician refers a patient to another physician or a healthcare facility and receives a portion of the charge in return. This survey was conducted to study general practitioners' (GPs) attitudes toward fee splitting as well as the prevalence, causes, and consequences of this process. This is a cross-sectional study on 223 general practitioners in 2013. Concerning the causes and consequences of fee splitting, an unpublished qualitative study was conducted by interviewing a number of GPs and specialists and the questionnaire options were the results of the information obtained from this study. Of the total 320 GPs, 247 returned the questionnaires. The response rate was 77.18%. Of the 247 returned questionnaires, 223 fulfilled the inclusion criteria. Among the participants, 69.1% considered fee splitting completely wrong and 23.2% (frequently or rarely) practiced fee splitting. The present study showed that the prevalence of fee splitting among physicians who had positive attitudes toward fee splitting was 4.63 times higher than those who had negative attitudes. In addition, this study showed that, compared to private hospitals, fee splitting is less practiced in public hospitals. The major cause of fee splitting was found to be unrealistic/unfair tariffs and the main consequence of fee splitting was thought to be an increase in the number of unnecessary patient referrals. Fee splitting is an unethical act, contradicts the goals of the medical profession, and undermines patient's best interest. In Iran, there is no code of ethics on fee splitting, but in this study, it was found that the majority of GPs considered it unethical. However, among those who had negative attitudes toward fee splitting, there were physicians who did practice fee splitting. The results of the study showed that physicians who had a positive attitude toward fee splitting practiced it more than others. Therefore, if physicians consider fee splitting unethical, its rate will certainly decrease. The study claims that to decrease such practice, the healthcare system has to revise the tariffs.

  6. Avoiding secondary skin graft donor site morbidity in the fibula free flap harvest.

    PubMed

    Kim, Paul D; Fleck, Terry; Heffelfinger, Ryan; Blackwell, Keith E

    2008-12-01

    To compare donor site morbidity in patients who have undergone fibula free flap reconstruction in which the skin graft was taken from the expected cutaneous paddle of the fibula with the known complications of the popular technique of obtaining a split-thickness skin graft (STSG) from a secondary donor site. Cohort study. The tertiary care centers at Loma Linda University Medical Center and University of California, Los Angeles, Medical Center. From September 1, 2006, to March 30, 2007, 30 patients underwent fibula free flap harvest by 2 surgeons at separate tertiary care centers. Twenty-one of those procedures took place at the University of California, Los Angeles, and 9 at Loma Linda University. Patients included 15 men (50%) and 15 women (50%), with a mean age of 58 (range, 19-88) years. All 30 patients underwent fibula free flap harvest with a split-thickness skin graft (graft thickness, 0.04 cm), obtained from osteocutaneous paddle using a 5.1-cm-wide dermatome, as well as oral cavity and oropharyngeal reconstruction with the de-epithelialized skin paddle. Measures of donor site morbidity, including graft failure and wound breakdown, and measures of recipient site morbidity, including flap failure, hardware complications, intraoral complications, and the need for additional surgery. Of the 30 patients who underwent this procedure, 4 had partial skin graft failures, for a complete skin graft survival of 87%. There were no complete skin graft losses. Regarding the fibula osteocutaneous free flap, there were no complete flap losses, 1 skin paddle necrosis that required debridement, 2 postoperative orocutaneous fistulas, 1 case of infected/extruded hardware, and 1 adhesion formation that required additional surgery for lysis of adhesion and placement of the split-thickness skin graft. The outlined novel technique has similar rates of free flap survival and skin graft take compared with previously described methods. Harvesting the skin graft over the expected osteocutaneous paddle results in decreased lower extremity morbidity by providing equivalent graft tissue for donor site closure and eliminating the morbidity of a secondary donor site. As long as there will not be 2 large opposing grafted surfaces, this technique should be considered when harvesting fibula free flaps for reconstruction of oromandibular resection defects, especially in cancers of the alveolar ridge and floor of the mouth.

  7. Preconditioned conjugate gradient methods for the compressible Navier-Stokes equations

    NASA Technical Reports Server (NTRS)

    Venkatakrishnan, V.

    1990-01-01

    The compressible Navier-Stokes equations are solved for a variety of two-dimensional inviscid and viscous problems by preconditioned conjugate gradient-like algorithms. Roe's flux difference splitting technique is used to discretize the inviscid fluxes. The viscous terms are discretized by using central differences. An algebraic turbulence model is also incorporated. The system of linear equations which arises out of the linearization of a fully implicit scheme is solved iteratively by the well known methods of GMRES (Generalized Minimum Residual technique) and Chebyschev iteration. Incomplete LU factorization and block diagonal factorization are used as preconditioners. The resulting algorithm is competitive with the best current schemes, but has wide applications in parallel computing and unstructured mesh computations.

  8. Automatic Parameterization Strategy for Cardiac Electrophysiology Simulations.

    PubMed

    Costa, Caroline Mendonca; Hoetzl, Elena; Rocha, Bernardo Martins; Prassl, Anton J; Plank, Gernot

    2013-10-01

    Driven by recent advances in medical imaging, image segmentation and numerical techniques, computer models of ventricular electrophysiology account for increasingly finer levels of anatomical and biophysical detail. However, considering the large number of model parameters involved parameterization poses a major challenge. A minimum requirement in combined experimental and modeling studies is to achieve good agreement in activation and repolarization sequences between model and experiment or patient data. In this study, we propose basic techniques which aid in determining bidomain parameters to match activation sequences. An iterative parameterization algorithm is implemented which determines appropriate bulk conductivities which yield prescribed velocities. In addition, a method is proposed for splitting the computed bulk conductivities into individual bidomain conductivities by prescribing anisotropy ratios.

  9. Combined orthognathic distraction procedure: Le Fort I maxillary osteotomy and mandibular curvilinear distraction osteogenesis. A new technique for craniofacial management.

    PubMed

    Schendel, Stephen A; Hazan-Molina, Hagai; Aizenbud, Dror

    2014-04-01

    Dentofacial deformities are traditionally treated by maxillary and mandibular osteotomies conducted separately or simultaneously. Recently, distraction osteogenesis has become an irreplaceable part of the surgical armamentarium, for its ability to induce new bone formation between the surfaces of bone segments that are gradually separated by incremental traction, along with a simultaneous expansion of the surrounding soft-tissue envelope. The aim of this article is to describe a combined surgical technique consisting of simultaneous maxillary Le Fort I advancement and mandibular surgical repositioning by means of bilateral sagittal split osteotomy with a curvilinear distractor based on a preliminary computerized presurgical prediction.

  10. Orbital trim by velocity factoring with applications to the Viking mission.

    NASA Technical Reports Server (NTRS)

    Kibler, J. F.; Green, R. N.; Young, G. R.

    1972-01-01

    An orbital trim technique has been developed to satisfy terminal rendezvous and intermediate timing constraints for planetary missions involving orbital operations. The technique utilizes a time-open two-impulse transfer from a specified initial orbit to a final orbit which satisfies all geometrical constraints. Each of the two impulses may then be factored, or split, into two or more vectorially equivalent impulses. The periods of the resulting intermediate orbits may be varied along with the number of revolutions in each orbit to satisfy the intermediate and final timing constraints. Factors in the range 0 to 1 result in rendezvous at the same cost as that of the two-impulse transfer. The technique is applied to the Viking mission to Mars although a similar procedure could be utilized for rendezvous operations about any planet.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Honorio, J.; Goldstein, R.; Honorio, J.

    We propose a simple, well grounded classification technique which is suited for group classification on brain fMRI data sets that have high dimensionality, small number of subjects, high noise level, high subject variability, imperfect registration and capture subtle cognitive effects. We propose threshold-split region as a new feature selection method and majority voteas the classification technique. Our method does not require a predefined set of regions of interest. We use average acros ssessions, only one feature perexperimental condition, feature independence assumption, and simple classifiers. The seeming counter-intuitive approach of using a simple design is supported by signal processing and statisticalmore » theory. Experimental results in two block design data sets that capture brain function under distinct monetary rewards for cocaine addicted and control subjects, show that our method exhibits increased generalization accuracy compared to commonly used feature selection and classification techniques.« less

  12. Time series evaluation of an intervention to increase statin tablet splitting by general practitioners.

    PubMed

    Polinski, Jennifer M; Schneeweiss, Sebastian; Maclure, Malcolm; Marshall, Blair; Ramsden, Samuel; Dormuth, Colin

    2011-02-01

    Tablet splitting, in which a higher-dose tablet is split to get 2 doses, reduces patients' drug costs. Statins can be split safely. General practitioners (GPs) may not direct their patients to split statins because of safety concerns or unawareness of costs. Medical chart inserts provide cost-effective education to physicians. The aim of this study was to assess whether providing GPs with statin-splitting chart inserts would increase splitting rates, and to identify predictors of splitting. In 2005 and 2006, we faxed a statin chart insert to British Columbia GPs with a request for a telephone interview. Consenting GPs were mailed 3 statin chart inserts and interviewed by phone (the intervention). In an interrupted time series, we compared monthly rates of statin-splitting prescriptions among intervention and nonintervention GPs before, during, and after the intervention. In multivariate logistic regressions accounting for patient clustering, predictors of splitting included physician and patient demographics and the specific statin prescribed. Of 5051 GPs reached, 282 (6%) agreed to the intervention. Before the intervention, GPs' splitting rate was 2.6%; after intervention, GPs' splitting rate was 7.5%. The rate for the nonintervention GPs was 4.4%. Intervention GPs were 1.68 (95% CI, 1.12-2.53) times more likely to prescribe splitting after the intervention than were nonintervention GPs. Other predictors were a patient's female sex (odds ratio [OR] = 1.26; 95% CI, 1.18-1.34), lower patient income (OR = 1.33; 95% CI, 1.18-1.34), and a lack of drug insurance (OR = 1.89; 95% CI, 1.69-2.04). An inexpensive intervention was effective in producing a sustained increase in GPs' splitting rate during 22 months of observed follow-up. Expanding statin-splitting education to all GPs might reduce prescription costs for many patients and payors. Copyright © 2011 Elsevier HS Journals, Inc. All rights reserved.

  13. Time series evaluation of an intervention to increase statin tablet splitting by general practitioners

    PubMed Central

    Polinski, Jennifer M.; Schneeweiss, Sebastian; Maclure, Malcolm; Marshall, Blair; Ramsden, Samuel; Dormuth, Colin

    2011-01-01

    Background Tablet splitting, in which a higher-dose tablet is split to get two doses, reduces patients’ drug costs. Statins can be split safely. General practitioners (GPs) may not direct their patients to split statins because of safety concerns or unawareness of costs. Medical chart inserts provide cost-effective education to physicians. We evaluated whether providing GPs with statin splitting chart inserts would increase splitting rates and identified predictors of splitting. Methods In 2005–2006, we faxed a statin chart insert to British Columbia GPs with a request for a telephone interview. Consenting GPs were mailed 3 statin chart inserts and interviewed by phone (the intervention). In an interrupted time series, we compared monthly rates of statin splitting prescriptions among intervention and non-intervention GPs before, during, and after the intervention. In multivariate logistic regressions accounting for patient clustering, predictors of splitting included physician and patient demographics and the specific statin prescribed. Results Of 5,051 GPs reached, 282 (6%) agreed to the intervention. Before the intervention, GPs’ splitting rate was 2.6%; after, intervention GPs’ splitting rate was 7.5%, non-intervention GPs’ was 4.4%. Intervention GPs were 1.68 (95% CI 1.12–2.53) times more likely to prescribe splitting after the intervention than were non-intervention GPs. Other predictors were a patient’s female sex (OR=1.26, 95% CI 1.18–1.34), lower patient income (OR=1.33, 95% CI 1.18–1.34), and no drug insurance (OR=1.89, 95% CI 1.69–2.04). Interpretation An inexpensive intervention was effective in producing a sustained increase in GPs’ splitting rate during 22 months of observed follow-up. Expanding statin splitting education to all GPs could reduce prescription costs for many patients and payors. PMID:21497707

  14. An Extension of the Split Window Technique for the Retrieval of Precipitable Water: Experimental Verification

    DTIC Science & Technology

    1988-09-23

    DOWNGRADING SCHEDULE D~istribution Unlimited 4. PERFORMING ORGANIZATiON REPORT NUMVBER(S) 5. MONITORiG ORGANIZATION REPORT NUMBER(S) AFGL-TR-88-0237...Collocations were performed on launch sites of the cloud contamination, aerosol problems, collocation 1200 UT radiosondes on 25 Aug 1987. Statistics were...al (1987) and Thomason, 1987). In this imagery opaque clouds to this problem appear white, low clouds and fog appear bright red against a brown

  15. A Comparison of Mandibular Transverse Dimensions of a Class I Normal and Class II Patient Population using Anterior to Posterior Measurement Ratios

    DTIC Science & Technology

    2012-04-13

    orthodontic and surgical options for intra-arch corrections. Instability of the mandible when expanded with removable appliances has been described by... orthodontic fields within the last ten years. This technique requires a surgical split at the symphysis followed by slow expansion, which allows hard...often viewed with much skepticism from the orthodontic and surgical communities. Indeed, there are definite limitations to corrections in this

  16. On the Scattering of the Electron off the Hydrogen Atom and the Helium Ion Below and Above the Ionization Threshold: Temkin-Poet Model

    NASA Astrophysics Data System (ADS)

    Yarevsky, E.; Yakovlev, S. L.; Elander, N.; Volkov, M. V.

    2014-08-01

    We generalize here the splitting approach to the long range (Coulomb) interaction for the three body scattering problem. With this approach, the exterior complex rotation technique can be applied for systems with asymptotic Coulomb interaction. We illustrate the method with calculations of the electron scattering on the hydrogen atom and positive helium ion in the frame of the Temkin-Poet model.

  17. Observation of the Meissner effect in a lattice Higgs model

    NASA Technical Reports Server (NTRS)

    Damgaard, Poul H.; Heller, Urs M.

    1988-01-01

    The lattice-regularized U(1) Higgs model in an external electromagnetic field is studied by Monte Carlo techniques. In the Coulomb phase, magnetic flux can flow through uniformly. The Higgs phase splits into a region where magnetic flux can penetrate only in the form of vortices and a region where the magnetic flux is completely expelled, the relativistic analog of the Meissner effect in superconductivity. Evidence is presented for symmetry restoration in strong external fields.

  18. A Report on Security of Overseas Transport. Volume 1. Project Hartwell.

    DTIC Science & Technology

    1950-09-21

    range of the JT gear extends only E up to 20,000 yards under the beat conditions, but it is quite V flexible, and the added advantage of triangulational...success upon the extent of this phase or amplitude modula- tion, likewise the use of binaural listening in large split arrays. These various aspects...specialized techniques, and aimed at integrating the beat possible use of sonic Lnder- water signals into over-all anti-submarine weapons systems

  19. Splitting of the Proximal Femur With a New Femoral Nail

    DTIC Science & Technology

    2010-04-01

    should be exercised with the use of new implants that require a change in customary technique. In addition, some concern must be raised by the amount of...the potential for gluteus medius tendon injury,8 whereas other authors have found greater soft-tissue injury by inserting a nail through the...Entry Femoral Nail (Synthes USA, Paoli, PA) moved the entry point further lateral (10 degrees) and distal to completely avoid the gluteus medius tendon

  20. The rotational spectrum of the water-hydroperoxy radical (H2O-HO2) complex.

    PubMed

    Suma, Kohsuke; Sumiyoshi, Yoshihiro; Endo, Yasuki

    2006-03-03

    Peroxy radicals and their derivatives are elusive but important intermediates in a wide range of oxidation processes. We observed pure rotational transitions of the water-hydroperoxy radical complex, H2O-HO2, in a supersonic jet by means of a Fourier transform microwave spectrometer combined with a double-resonance technique. The observed rotational transitions were found to split into two components because of the internal rotation of the water moiety. The molecular constants for the two components were determined precisely, supporting a molecular structure in which HO2 acts as a proton donor to form a nearly planar five-membered ring, and one hydrogen atom of water sticks out from the ring plane. The structure and the spectral splittings due to internal rotation provide information on the nature of the bonding interaction between open- and closed-shell species, and they also provide accurate transition frequencies that are applicable to remote sensing of this complex, which may elucidate its potential roles in atmospheric and combustion chemistry.

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