Sample records for splitting test influence

  1. Pharmaceutical counselling about different types of tablet-splitting methods based on the results of weighing tests and mechanical development of splitting devices.

    PubMed

    Somogyi, O; Meskó, A; Csorba, L; Szabó, P; Zelkó, R

    2017-08-30

    The division of tablets and adequate methods of splitting them are a complex problem in all sectors of health care. Although tablet-splitting is often required, this procedure can be difficult for patients. Four tablets were investigated with different external features (shape, score-line, film-coat and size). The influencing effect of these features and the splitting methods was investigated according to the precision and "weight loss" of splitting techniques. All four types of tablets were halved by four methods: by hand, with a kitchen knife, with an original manufactured splitting device and with a modified tablet splitter based on a self-developed mechanical model. The mechanical parameters (harness and friability) of the products were measured during the study. The "weight loss" and precision of splitting methods were determined and compared by statistical analysis. On the basis of the results, the external features (geometry), the mechanical parameters of tablets and the mechanical structure of splitting devices can influence the "weight loss" and precision of tablet-splitting. Accordingly, a new decision-making scheme was developed for the selection of splitting methods. In addition, the skills of patients and the specialties of therapy should be considered so that pharmaceutical counselling can be more effective regarding tablet-splitting. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Experimental Study On The Effect Of Micro-Cracks On Brazilian Tensile Strength

    NASA Astrophysics Data System (ADS)

    Wang, Xiangyu

    2015-12-01

    For coal mine ground control issues, it is necessary to propose a failure criteria accounting for the transversely isotropic behaviors of rocks. Hence, it is very helpful to provide experimental data for the validation of the failure criteria. In this paper, the method for preparing transversely isotropic specimens and the scheme of the Brazilian tensile strength test are presented. Results obtained from Brazilian split tests under dry and water-saturated conditions reflect the effect of the development direction β of the structural plane, such as the bedding fissure, on the tensile strength, ultimate displacement, failure mode, and the whole splitting process. The results show that the tensile strength decreases linearly with increasing β. The softening coefficient of the tensile strength shows a sinusoidal function. The values of the slope and inflection point for the curve vary at the different stages of the Brazilian test. The failure mode of the rock specimen presented in this paper generally coincides with the standard Brazilian splitting failure mode. Based on the test results, the major influencing factors for the Brazilian splitting strength are analyzed and a mathematical model for solving the Brazilian splitting strength is proposed. The findings in this paper would greatly benefit the coal mine ground control studies when the surrounding rocks of interest show severe transversely isotropic behaviors.

  3. Special Workshop: Kolsky/Split Hopkinson Pressure Bar Testing of Ceramics

    DTIC Science & Technology

    2006-09-01

    merit) control armor performance and how these properties are controlled/ influenced by intrinsic (crystal structure, phase transitions, and single...reproducibility uncertainties (estimates of precision) could be quantified and also identify key parameters that should be controlled in SHPB/Kolsky testing...control performance? Are there figures of merit? How are the mechanical properties influenced by intrinsic and extrinsic material characteristics

  4. Fundamental metallurgical aspects of axial splitting in zircaloy cladding

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chung, H. M.

    Fundamental metallurgical aspects of axial splitting in irradiated Zircaloy cladding have been investigated by microstructural characterization and analytical modeling, with emphasis on application of the results to understand high-burnup fuel failure under RIA situations. Optical microscopy, SEM, and TEM were conducted on BWR and PWR fuel cladding tubes that were irradiated to fluence levels of 3.3 x 10{sup 21} n cm{sup {minus}2} to 5.9 x 10{sup 21} n cm{sup {minus}2} (E > 1 MeV) and tested in hot cell at 292--325 C in Ar. The morphology, distribution, and habit planes of macroscopic and microscopic hydrides in as-irradiated and posttest claddingmore » were determined by stereo-TEM. The type and magnitude of the residual stress produced in association with oxide-layer growth and dense hydride precipitation, and several synergistic factors that strongly influence axial-splitting behavior were analyzed. The results of the microstructural characterization and stress analyses were then correlated with axial-splitting behavior of high-burnup PWR cladding reported for simulated-RIA conditions. The effects of key test procedures and their implications for the interpretation of RIA test results are discussed.« less

  5. A modified split Hopkinson pressure bar for toughness tests

    NASA Astrophysics Data System (ADS)

    Granier, N.; Grunenwald, T.

    2006-08-01

    In order to characterize material toughness or to study crack arrest under dynamic loading conditions, a new testing device has been developed at CEA/Valduc. A new Split Hopkinson Pressure Bar (SHPB) has been modified: it is now composed of a single incident bar and a double transmitter bar. With this facility, a notched specimen can be loaded under three points bending conditions. Qualification tests with titanium and steel notched samples are presented. Data treatment software has been adapted to estimate the sample deflection as a function of time and treat the energy balance. These results are compared with classical Charpy experiments. Effect of various contact areas between specimen and bars are studied to point out their influence on obtained measurements. The advantage of a “knife” contact compared to a plane one is then clearly demonstrated. All results obtained with this new testing device are in good agreement and show a reduced scattering.

  6. Dynamics of a split torque helicopter transmission

    NASA Technical Reports Server (NTRS)

    Rashidi, Majid; Krantz, Timothy

    1992-01-01

    A high reduction ratio split torque gear train has been proposed as an alternative to a planetary configuration for the final stage of a helicopter transmission. A split torque design allows a high ratio of power-to-weight for the transmission. The design studied in this work includes a pivoting beam that acts to balance thrust loads produced by the helical gear meshes in each of two parallel power paths. When the thrust loads are balanced, the torque is split evenly. A mathematical model was developed to study the dynamics of the system. The effects of time varying gear mesh stiffness, static transmission errors, and flexible bearing supports are included in the model. The model was demonstrated with a test case. Results show that although the gearbox has a symmetric configuration, the simulated dynamic behavior of the first and second compound gears are not the same. Also, results show that shaft location and mesh stiffness tuning are significant design parameters that influence the motions of the system.

  7. 49 CFR 40.171 - How does an employee request a test of a split specimen?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false How does an employee request a test of a split specimen? 40.171 Section 40.171 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Split Specimen Tests § 40.171 How does an employee request a test of a split specimen? (a...

  8. Effects of Shade on Blue Oak and Coast Live Oak Regeneration in California Annual Grasslands

    Treesearch

    Pamela C. Muick

    1991-01-01

    Canopy effects and annual vegetation have been shown to strongly influence oak seedling survival. From the many elements composing canopy, shade was selected for experimental manipulation. A split-plot, multifactorial experiment was designed to test whether blue oak (Quercus douglasii) and coast live oak (Q. agrifolia) could...

  9. Fracture patterns after bilateral sagittal split osteotomy of the mandibular ramus according to the Obwegeser/Dal Pont and Hunsuck/Epker modifications.

    PubMed

    Möhlhenrich, Stephan Christian; Kniha, Kristian; Peters, Florian; Ayoub, Nassim; Goloborodko, Evgeny; Hölzle, Frank; Fritz, Ulrike; Modabber, Ali

    2017-05-01

    The aim of this study was to compare the fracture patterns after sagittal split osteotomy according to Obwegeser/Dal Pont (ODP) and Hunsuck/Epker (HE), as well as to investigate the relationship between lateral bone cut ending or angle and the incidence of unfavorable/bad splits. Postoperative cone-beam computed tomograms of 124 splits according to ODP and 60 according to HE were analyzed. ODP led to 75.8% and HE led to 60% lingual fractures with mandibular foramen contact. Horizontal fractures were found in 9.7% and 6.7%, respectively, and unfavorable/bad splits were found in 11.3% and 10%, respectively. The lateral osteotomy angle was 106.22° (SD 12.03)° for bad splits and 106.6° (SD 13.12)° for favorable splits. Correlations were found between favorable fracture patterns and split modifications and between buccal ending of the lateral bone cut and bad splits (p < 0.001). No relationship was observed between split modifications (p = 0.792) or the osteotomy angle (p = 0.937) and the incidence of unfavorable/bad splits. Split modifications had no influence on the incidence of unfavorable/bad splits, but the buccal ending of the lateral bone cut did have an influence. More lingual fractures with mandibular foramen contact are expected with the ODP modification. The osteotomy angle did not differ between favorable and bad splits. Copyright © 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  10. Strain Measurements within Fibreboard. Part III: Analyzing the Process Zone at the Crack Tip of Medium Density Fiberboards (MDF) Double Cantilever I-Beam Specimens

    PubMed Central

    Rathke, Jörn; Müller, Ulrich; Konnerth, Johannes; Sinn, Gerhard

    2012-01-01

    This paper is the third part of a study dealing with the mechanical and fracture mechanical characterization of Medium Density Fiberboards (MDF). In the first part, an analysis of internal bond strength testing was performed and in the second part MDF was analyzed by means of the wedge splitting experiment; this part deals with the double cantilever I beam test, which is designed for measuring the fracture energy as well as stress intensity factor in Mode I. For a comparison of isotropic and orthotropic material behavior, finite element modeling was performed. In addition to the calculation of fracture energy the stress intensity factor was analyzed by means of finite elements simulation and calculation. In order to analyze strain deformations and the process zone, electronic speckle pattern interferometry measurements were performed. The results revealed an elongated process zone and lower results for KIC if compared to the wedge splitting experiment. The Gf numbers are higher compared to the wedge splitting results and can be explained by the thicker process zone formed during the crack propagation. The process zone width on its part is influenced by the stiff reinforcements and yields a similar crack surface as with the internal bond test.

  11. 10 CFR 26.135 - Split specimens.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Split specimens. 26.135 Section 26.135 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Licensee Testing Facilities § 26.135 Split specimens. (a) If the FFD program follows split-specimen procedures, as described in § 26.113, the licensee testing...

  12. 10 CFR 26.135 - Split specimens.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Split specimens. 26.135 Section 26.135 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Licensee Testing Facilities § 26.135 Split specimens. (a) If the FFD program follows split-specimen procedures, as described in § 26.113, the licensee testing...

  13. 10 CFR 26.135 - Split specimens.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Split specimens. 26.135 Section 26.135 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Licensee Testing Facilities § 26.135 Split specimens. (a) If the FFD program follows split-specimen procedures, as described in § 26.113, the licensee testing...

  14. 10 CFR 26.135 - Split specimens.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Split specimens. 26.135 Section 26.135 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Licensee Testing Facilities § 26.135 Split specimens. (a) If the FFD program follows split-specimen procedures, as described in § 26.113, the licensee testing...

  15. 10 CFR 26.135 - Split specimens.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Split specimens. 26.135 Section 26.135 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Licensee Testing Facilities § 26.135 Split specimens. (a) If the FFD program follows split-specimen procedures, as described in § 26.113, the licensee testing...

  16. Engineering Properties and Correlation Analysis of Fiber Cementitious Materials

    PubMed Central

    Lin, Wei-Ting; Wu, Yuan-Chieh; Cheng, An; Chao, Sao-Jeng; Hsu, Hui-Mi

    2014-01-01

    This study focuses on the effect of the amount of silica fume addition and volume fraction of steel fiber on the engineering properties of cementitious materials. Test variables include dosage of silica fume (5% and 10%), water/cement ratio (0.35 and 0.55) and steel fiber dosage (0.5%, 1.0% and 2.0%). The experimental results included: compressive strength, direct tensile strength, splitting tensile strength, surface abrasion and drop-weight test, which were collected to carry out the analysis of variance to realize the relevancy and significance between material parameters and those mechanical properties. Test results illustrate that the splitting tensile strength, direct tensile strength, strain capacity and ability of crack-arresting increase with increasing steel fiber and silica fume dosages, as well as the optimum mixture of the fiber cementitious materials is 5% replacement silica fume and 2% fiber dosage. In addition, the Pearson correlation coefficient was conducted to evaluate the influence of the material variables and corresponds to the experiment result. PMID:28788256

  17. Does Socio-Economic Status Moderate the Associations between Psychosocial Predictors and Fruit Intake in Schoolchildren? The Pro Children Study

    ERIC Educational Resources Information Center

    Sandvik, C.; Gjestad, R.; Samdal, O.; Brug, J.; Klepp, K. -I.

    2010-01-01

    This study tested whether socio-economic status (SES) moderated the association between the psychosocial constructs included in the attitude-social influence-self-efficacy (ASE) model and fruit intake in Norwegian schoolchildren. The sample consisted of 962 Norwegian sixth graders, mean age 11.3 years. They were split into three SES groups, and…

  18. 49 CFR 40.181 - What does the second laboratory do with the split specimen when it is tested to reconfirm a...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false What does the second laboratory do with the split specimen when it is tested to reconfirm a substituted test result? 40.181 Section 40.181 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Split Specimen Tests § 40.181...

  19. 49 CFR 40.179 - What does the second laboratory do with the split specimen when it is tested to reconfirm an...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false What does the second laboratory do with the split specimen when it is tested to reconfirm an adulterated test result? 40.179 Section 40.179 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Split Specimen Tests § 40.17...

  20. 49 CFR 40.173 - Who is responsible for paying for the test of a split specimen?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Who is responsible for paying for the test of a split specimen? 40.173 Section 40.173 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Split Specimen Tests § 40.173 Who is responsible for paying for the test of a spli...

  1. Biochar application mode influences nitrogen leaching and NH3 volatilization losses in a rice paddy soil irrigated with N-rich wastewater.

    PubMed

    Sun, Haijun; Min, Ju; Zhang, Hailin; Feng, Yanfang; Lu, Kouping; Shi, Weiming; Yu, Min; Li, Xuewen

    2017-07-11

    Impacts of biochar application mode on nitrogen (N) leaching, ammonia (NH 3 ) volatilization, rice grain yield and N use efficiency (NUE) are not well understood. Therefore, a field experiment was conducted to evaluate those impacts in a rice paddy soil received 225 kg N ha -1 from either urea or N-rich wastewater. One treatment received 10 t ha -1 biochar with the basal fertilization, and the other received same total amount of biochar but split applied with the three split N applications with same ratio as N fertilizer split ratio (40%, 30% and 30%). Results showed that N leaching loads were 4.20-6.22 kg ha -1 . Biochar one-time application reduced N leaching by 23.1%, and biochar split application further reduced N leaching by 32.4%. Total NH 3 volatilization loss was 15.5-24.5 kg ha -1 . Biochar one-time application did not influence the NH 3 volatilization, but biochar split application stimulated the cumulative NH 3 volatilization by 57.7%. Both biochar treatments had no influence on NUE and rice grain yield. In conclusion, biochar application mode indeed influences the N leaching and NH 3 volatilization in rice paddy soils, and biochar one-time application should be recommended for reducing N leaching without increasing NH 3 volatilization.

  2. Enhanced retinal vasculature imaging with a rapidly configurable aperture

    PubMed Central

    Sapoznik, Kaitlyn A.; Luo, Ting; de Castro, Alberto; Sawides, Lucie; Warner, Raymond L.; Burns, Stephen A.

    2018-01-01

    In adaptive optics scanning laser ophthalmoscope (AOSLO) systems, capturing multiply scattered light can increase the contrast of the retinal microvasculature structure, cone inner segments, and retinal ganglion cells. Current systems generally use either a split detector or offset aperture approach to collect this light. We tested the ability of a spatial light modulator (SLM) as a rapidly configurable aperture to use more complex shapes to enhance the contrast of retinal structure. Particularly, we varied the orientation of a split detector aperture and explored the use of a more complex shape, the half annulus, to enhance the contrast of the retinal vasculature. We used the new approach to investigate the influence of scattering distance and orientation on vascular imaging. PMID:29541524

  3. Torque Splitting by a Concentric Face Gear Transmission

    NASA Technical Reports Server (NTRS)

    Filler, Robert R.; Heath, Gregory F.; Slaughter, Stephen C.; Lewicki, David G.

    2002-01-01

    Tests of a 167 Kilowatt (224 Horsepower) split torque face gearbox were performed by the Boeing Company in Mesa, Arizona, while working under a Defense Advanced Research Projects Agency (DARPA) Technology Reinvestment Program (TRP). This paper provides a summary of these cooperative tests, which were jointly funded by Boeing and DARPA. Design, manufacture and testing of the scaled-power TRP proof-of-concept (POC) split torque gearbox followed preliminary evaluations of the concept performed early in the program. The split torque tests were run using 200 N-m (1767 in-lbs) torque input to each side of the transmission. During tests, two input pinions were slow rolled while in mesh with the two face gears. Two idler gears were also used in the configuration to recombine torque near the output. Resistance was applied at the output face gear to create the required loading conditions in the gear teeth. A system of weights, pulleys and cables were used in the test rig to provide both the input and output loading. Strain gages applied in the tooth root fillets provided strain indication used to determine torque splitting conditions at the input pinions. The final two pinion-two idler tests indicated 52% to 48% average torque split capabilities for the two pinions. During the same tests, a 57% to 43% average distribution of the torque being recombined to the upper face gear from the lower face gear was measured between the two idlers. The POC split torque tests demonstrated that face gears can be applied effectively in split torque rotorcraft transmissions, yielding good potential for significant weight, cost and reliability improvements over existing equipment using spiral bevel gearing.

  4. Development of Face Gear Technology for Industrial and Aerospace Power Transmission

    NASA Technical Reports Server (NTRS)

    Heath, Gregory F.; Filler, Robert R.; Tan, Jie

    2002-01-01

    Tests of a 250 horsepower proof-of-concept (POC) split torque face gear transmission were completed by The Boeing Company in Mesa, Arizona, while working under a Defense Advanced Research Projects Agency (DARPA) Technology Reinvestment Program (TRP) This report provides a summary of these cooperative tests, which were jointly funded by Boeing and DARPA Design, manufacture and testing of the scaled-power TRP split torque gearbox followed preliminary evaluations of the concept performed early in the program The testing demonstrated the theory of operation for the concentric, tapered face gear assembly The results showed that the use of floating pinions in a concentric face gear arrangement produces a nearly even torque split The POC split torque tests determined that, with some improvements, face gears can be applied effectively in a split torque configuration which yields significant weight, cost and reliability improvements over conventional designs.

  5. Kondo peak splitting and Kondo dip in single molecular magnet junctions

    NASA Astrophysics Data System (ADS)

    Niu, Pengbin; Shi, Yunlong; Sun, Zhu; Nie, Yi-Hang; Luo, Hong-Gang

    2016-01-01

    Many factors containing bias, spin-orbit coupling, magnetic fields applied, and so on can strongly influence the Kondo effect, and one of the consequences is Kondo peak splitting (KPS). It is natural that KPS should also appear when another spin degree of freedom is involved. In this work we study the KPS effects of single molecular magnets (SMM) coupled with two metallic leads in low-temperature regime. It is found that the Kondo transport properties are strongly influenced by the exchange coupling and anisotropy of the magnetic core. By employing Green's function method in Hubbard operator representation, we give an analytical expression for local retarded Green's function of SMM and discussed its low-temperature transport properties. We find that the anisotropy term behaves as a magnetic field and the splitting behavior of exchange coupling is quite similar to the spin-orbit coupling. These splitting behaviors are explained by introducing inter-level or intra-level transitions, which account for the seven-peak splitting structure. Moreover, we find a Kondo dip at Fermi level under proper parameters. These Kondo peak splitting behaviors in SMM deepen our understanding to Kondo physics and should be observed in the future experiments.

  6. Influence of the large-small split effect on strategy choice in complex subtraction.

    PubMed

    Xiang, Yan Hui; Wu, Hao; Shang, Rui Hong; Chao, Xiaomei; Ren, Ting Ting; Zheng, Li Ling; Mo, Lei

    2018-04-01

    Two main theories have been used to explain the arithmetic split effect: decision-making process theory and strategy choice theory. Using the inequality paradigm, previous studies have confirmed that individuals tend to adopt a plausibility-checking strategy and a whole-calculation strategy to solve large and small split problems in complex addition arithmetic, respectively. This supports strategy choice theory, but it is unknown whether this theory also explains performance in solving different split problems in complex subtraction arithmetic. This study used small, intermediate and large split sizes, with each split condition being further divided into problems requiring and not requiring borrowing. The reaction times (RTs) for large and intermediate splits were significantly shorter than those for small splits, while accuracy was significantly higher for large and middle splits than for small splits, reflecting no speed-accuracy trade-off. Further, RTs and accuracy differed significantly between the borrow and no-borrow conditions only for small splits. This study indicates that strategy choice theory is suitable to explain the split effect in complex subtraction arithmetic. That is, individuals tend to choose the plausibility-checking strategy or the whole-calculation strategy according to the split size. © 2016 International Union of Psychological Science.

  7. Multi-response optimization of Artemia hatching process using split-split-plot design based response surface methodology

    PubMed Central

    Arun, V. V.; Saharan, Neelam; Ramasubramanian, V.; Babitha Rani, A. M.; Salin, K. R.; Sontakke, Ravindra; Haridas, Harsha; Pazhayamadom, Deepak George

    2017-01-01

    A novel method, BBD-SSPD is proposed by the combination of Box-Behnken Design (BBD) and Split-Split Plot Design (SSPD) which would ensure minimum number of experimental runs, leading to economical utilization in multi- factorial experiments. The brine shrimp Artemia was tested to study the combined effects of photoperiod, temperature and salinity, each with three levels, on the hatching percentage and hatching time of their cysts. The BBD was employed to select 13 treatment combinations out of the 27 possible combinations that were grouped in an SSPD arrangement. Multiple responses were optimized simultaneously using Derringer’s desirability function. Photoperiod and temperature as well as temperature-salinity interaction were found to significantly affect the hatching percentage of Artemia, while the hatching time was significantly influenced by photoperiod and temperature, and their interaction. The optimum conditions were 23 h photoperiod, 29 °C temperature and 28 ppt salinity resulting in 96.8% hatching in 18.94 h. In order to verify the results obtained from BBD-SSPD experiment, the experiment was repeated preserving the same set up. Results of verification experiment were found to be similar to experiment originally conducted. It is expected that this method would be suitable to optimize the hatching process of animal eggs. PMID:28091611

  8. 76 FR 19759 - Energy Conservation Program for Certain Industrial Equipment: Publication of the Petition for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-08

    ... (``VRF'') multi-split systems. Carrier requests this waiver for the SMMSi systems because the basic design of VRF multi-split systems prevents testing or rating according to DOE's prescribed test... adopted by AHRI--``ANSI/AHRI 1230--2010: Performance Rating of Variable Refrigerant Flow (VRF) Multi-Split...

  9. Influence of different gaps among the split targets with gradient potential to the discharge effects generated by hypervelocity impact

    NASA Astrophysics Data System (ADS)

    Tang, Enling; Zhao, Liangliang; Han, Yafei; Zhang, Qingming; Wang, Ruizhi; He, Liping; Liu, Shuhua

    2018-04-01

    Due to the actual situation of spacecraft surface' charging, such as convex corners, weld line, whalebone and a multiple-interfaces with different materials, all these are main factors leading to uneven charging of spacecraft surface, even creating gradient potential. If the charging spacecraft surface is impacted by debris or micrometeor, discharge effect induced by impacting will pose a serious threat to spacecraft in orbit. So realizing spacecraft charging surface with different potential differences and grasping discharge characteristics are a decisive importance at the different experimental conditions in laboratory. To simulate the spacecraft surface with a gradient potential in laboratory, spacecraft surface is split into different parts, which different gaps reserved in 2 adjacent surface is added resistance to create different potential surfaces, and the high potential surface as a impact target in the split targets. Charging circuit system realizing different gradient potential and discharge test system are built by ourselves, combining with two-stage light gas gun loading system, six sets of experiments have been performed about hypervelocity impact on 2A12 aluminum split targets with gradient potentials. In the experiments, gaps of 2A12 aluminum target are the same among different parts in every experiments, the gaps of the split targets are 2mm, 3mm, 5mm, 7mm and 10mm in the experiments, respectively. And the applied voltage is 300V in all the experiments and high-potential 2A12 aluminum plate as the impact target. The experiments have been performed at the impact velocity of about 3km/s and the incidence angles of 60o and 90o (between projectile flying trajectory and target plane), respectively. Voltage probe and current probes are used for acquiring discharge voltages and currents during the process of the impact. The experimental results showed that the discharge induced by impact plasma were generated among high and low-potential target by forming a plasma discharge channel. With the increasing of the gaps among the high and low-potential targets, the peak values of the discharge current decreased first then increased. When the gaps of split targets reached a certain value, the peak values of the discharge current decreased again. Meanwhile, the gaps among high and low-potential targets was 5mm, the peak value of the discharge current was the smallest. With the increasing of the gaps among the split targets, a primary discharge duration also increased. However, when the gaps among the split targets were greater than 5mm, increasing trend of discharge duration would slow down. When the gaps among the split targets were greater than 7mm, there was a secondary discharge phenomenon, and the physical explanations were given about the influence of different gaps among the split targets on the discharge effects created by hypervelocity impact.

  10. [Comparisons and analysis of the spectral response functions' difference between FY-2E's and FY2C's split window channels].

    PubMed

    Zhang, Yong; Li, Yuan; Rong, Zhi-Guo

    2010-06-01

    Remote sensors' channel spectral response function (SRF) was one of the key factors to influence the quantitative products' inversion algorithm, accuracy and the geophysical characteristics. Aiming at the adjustments of FY-2E's split window channels' SRF, detailed comparisons between the FY-2E and FY-2C corresponding channels' SRF differences were carried out based on three data collections: the NOAA AVHRR corresponding channels' calibration look up tables, field measured water surface radiance and atmospheric profiles at Lake Qinghai and radiance calculated from the PLANK function within all dynamic range of FY-2E/C. The results showed that the adjustments of FY-2E's split window channels' SRF would result in the spectral range's movements and influence the inversion algorithms of some ground quantitative products. On the other hand, these adjustments of FY-2E SRFs would increase the brightness temperature differences between FY-2E's two split window channels within all dynamic range relative to FY-2C's. This would improve the inversion ability of FY-2E's split window channels.

  11. Prevalence of depressive symptoms among college students and the influence of sport activity.

    PubMed

    Uglesić, Boran; Lasić, Davor; Zuljan-Cvitanović, Marija; Buković, Damir; Karelović, Deni; Delić-Brkljacić, Diana; Buković, Nevia; Radan, Mirjana

    2014-03-01

    The present study asses the prevalence of depressive symptoms among college students in Split, Croatia, and positive influence of sport activity on decreasing the depression symptoms. Authors screened all 664 college students of the first year of study. All of them were over the 18 years and the mean age was 19.4 +/- 1.2 years. There were 466 females (70.2%) and 178 (26.8%) males. They answered The Beck Depression Inventory (BDI) and questionnaire about their sport activity (no sport activity, recreational and active in sports). For the purpose of the analysis depressive symptoms were defined as a score of > 11. Chi-square and Mann-Whitney test were used for data analysis. 9.4% of the students had significant depression symptoms (score > 11). No one student had score > 26 (symptoms of major depression). Statistically significant lower score on BDI have students who are active in sports (score median = 3) compared to group of recreational (score median = 4) and in correlation to group who are not active in sports (score median = 5) (Kruskal-Wallis: p < 0.001). In the group of active in sports (N = 254) there are only 5.5% with depressions symptoms, while in the group of non active in sports (N = 60) are 18 depressive (chi2-test: p = 0,005). Females are statistically more depressed than males (chi2-test: p = 0.01). In the female group 49 (10.5%) are depressed, and in the male group are 9 (5%). Compared to gender in separate analysis we did not find correlation of decreasing depression symptoms and sport activity among males (chi2-test: p = 0.47), while in females we find that sport activity has significant effect (chi2-test: p = 0.026). Our results shoved moderate values of depression symptoms among college population in Split, Croatia. More females than males experienced depressive symptoms. While sport activity did not have significant influence on the depression in male population, it has significant influence in reducing the depression symptoms among females.

  12. Measurement of fracture toughness by nanoindentation methods: Recent advances and future challenges

    DOE PAGES

    Sebastiani, Marco; Johanns, K. E.; Herbert, Erik G.; ...

    2015-04-30

    In this study, we describe recent advances and developments for the measurement of fracture toughness at small scales by the use of nanoindentation-based methods including techniques based on micro-cantilever beam bending and micro-pillar splitting. A critical comparison of the techniques is made by testing a selected group of bulk and thin film materials. For pillar splitting, cohesive zone finite element simulations are used to validate a simple relationship between the critical load at failure, the pillar radius, and the fracture toughness for a range of material properties and coating/substrate combinations. The minimum pillar diameter required for nucleation and growth ofmore » a crack during indentation is also estimated. An analysis of pillar splitting for a film on a dissimilar substrate material shows that the critical load for splitting is relatively insensitive to the substrate compliance for a large range of material properties. Experimental results from a selected group of materials show good agreement between single cantilever and pillar splitting methods, while a discrepancy of ~25% is found between the pillar splitting technique and double-cantilever testing. It is concluded that both the micro-cantilever and pillar splitting techniques are valuable methods for micro-scale assessment of fracture toughness of brittle ceramics, provided the underlying assumptions can be validated. Although the pillar splitting method has some advantages because of the simplicity of sample preparation and testing, it is not applicable to most metals because their higher toughness prevents splitting, and in this case, micro-cantilever bend testing is preferred.« less

  13. 76 FR 31951 - Energy Conservation Program for Certain Commercial and Industrial Equipment: Decision and Order...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ... specific to the Carrier Super Modular Multi-System (SMMSi) variable refrigerant flow (VRF) multi-split... in this notice to test and rate its SMMSi VRF multi-split commercial heat pumps. DATES: This Decision... its SMMSi VRF multi-split products. Carrier must use the alternate test procedure provided in this...

  14. 49 CFR 40.183 - What information do laboratories report to MROs regarding split specimen results?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false What information do laboratories report to MROs regarding split specimen results? 40.183 Section 40.183 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Split Specimen Tests § 40.183 What information do laboratories...

  15. Stepwise Splitting Growth and Pseudocapacitive Properties of Hierarchical Three-Dimensional Co3O4 Nanobooks

    PubMed Central

    Chen, Huilong; Lu, Shuang; Gong, Feilong; Liu, Huanzhen; Li, Feng

    2017-01-01

    Three-dimensional hierarchical Co3O4 nanobooks have been synthesized successfully on a large scale by calcining orthorhombic Co(CO3)0.5(OH)·0.11H2O precursors with identical morphologies. Based on the influence of reaction time and urea concentration on the nanostructures of the precursors, a stepwise splitting growth mechanism can be proposed to understand the formation of the 3D nanobooks. The 3D Co3O4 nanobooks exhibit excellent pseudocapacitive performances with specific capacitances of 590, 539, 476, 453, and 421 F/g at current densities of 0.5, 1, 2, 4, and 8 A/g, respectively. The devices can retain ca. 97.4% of the original specific capacitances after undergoing charge–discharge cycle tests 1000 times continuously at 4 A/g. PMID:28394297

  16. 10 CFR 26.113 - Splitting the urine specimen.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Splitting the urine specimen. 26.113 Section 26.113 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Collecting Specimens for Testing § 26.113 Splitting the urine specimen. (a) Licensees and other entities may, but are not required to, use split...

  17. 10 CFR 26.113 - Splitting the urine specimen.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Splitting the urine specimen. 26.113 Section 26.113 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Collecting Specimens for Testing § 26.113 Splitting the urine specimen. (a) Licensees and other entities may, but are not required to, use split...

  18. 10 CFR 26.113 - Splitting the urine specimen.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Splitting the urine specimen. 26.113 Section 26.113 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Collecting Specimens for Testing § 26.113 Splitting the urine specimen. (a) Licensees and other entities may, but are not required to, use split...

  19. 10 CFR 26.113 - Splitting the urine specimen.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Splitting the urine specimen. 26.113 Section 26.113 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Collecting Specimens for Testing § 26.113 Splitting the urine specimen. (a) Licensees and other entities may, but are not required to, use split...

  20. 10 CFR 26.113 - Splitting the urine specimen.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Splitting the urine specimen. 26.113 Section 26.113 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Collecting Specimens for Testing § 26.113 Splitting the urine specimen. (a) Licensees and other entities may, but are not required to, use split...

  1. Biomechanical comparison of a novel engine-driven ridge spreader and conventional ridge splitting techniques.

    PubMed

    Jung, Gyu-Un; Kim, Jun Hwan; Lim, Nam Hun; Yoon, Gil Ho; Han, Ji-Young

    2017-06-01

    Ridge splitting techniques are used for horizontal ridge augmentation in implant dentistry. Recently, a novel engine-driven ridge splitting technique was introduced. This study compared the mechanical forces produced by conventional and engine-driven ridge splitting techniques in porcine mandibles. In 33 pigs, mandibular premolar areas were selected for the ridge splitting procedures, designed as a randomized split-mouth study. The conventional group underwent a chisel-and-mallet procedure (control group, n = 20), and percussive impulse (Newton second, Ns) was measured using a sensor attached to the mallet. In the engine-driven ridge spreader group (test group, n = 23), a load cell was used to measure torque values (Newton centimeter, Ncm). Horizontal acceleration generated during procedures (control group, n = 10 and test group, n = 10) was compared between the groups. After ridge splitting, the alveolar crest width was significantly increased both in the control (1.23 ± 0.45 mm) and test (0.98 ± 0.41 mm) groups with no significant differences between the groups. The average impulse of the control group was 4.74 ± 1.05 Ns. Torque generated by rotation in the test group was 9.07 ± 2.15 Ncm. Horizontal acceleration was significantly less in the test group (0.82 ± 1.05 g) than the control group (64.07 ± 42.62 g) (P < 0.001). Narrow edentulous ridges can be expanded by novel engine-driven ridge spreaders. Within the limits of this study, the results suggested that an engine-driven ridge splitting technique may be less traumatic and less invasive than a conventional ridge splitting technique. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Methods for pore water extraction from unsaturated zone tuff, Yucca Mountain, Nevada

    USGS Publications Warehouse

    Scofield, K.M.

    2006-01-01

    Assessing the performance of the proposed high-level radioactive waste repository at Yucca Mountain, Nevada, requires an understanding of the chemistry of the water that moves through the host rock. The uniaxial compression method used to extract pore water from samples of tuffaceous borehole core was successful only for nonwelded tuff. An ultracentrifugation method was adopted to extract pore water from samples of the densely welded tuff of the proposed repository horizon. Tests were performed using both methods to determine the efficiency of pore water extraction and the potential effects on pore water chemistry. Test results indicate that uniaxial compression is most efficient for extracting pore water from nonwelded tuff, while ultracentrifugation is more successful in extracting pore water from densely welded tuff. Pore water splits collected from a single nonwelded tuff core during uniaxial compression tests have shown changes in pore water chemistry with increasing pressure for calcium, chloride, sulfate, and nitrate. Pore water samples collected from the intermediate pressure ranges should prevent the influence of re-dissolved, evaporative salts and the addition of ion-deficient water from clays and zeolites. Chemistry of pore water splits from welded and nonwelded tuffs using ultracentrifugation indicates that there is no substantial fractionation of solutes.

  3. 49 CFR 40.185 - Through what methods and to whom must a laboratory report split specimen results?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Through what methods and to whom must a laboratory report split specimen results? 40.185 Section 40.185 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Split Specimen Tests § 40.185 Through what methods and to whom...

  4. Enzyme-linked small-molecule detection using split aptamer ligation.

    PubMed

    Sharma, Ashwani K; Kent, Alexandra D; Heemstra, Jennifer M

    2012-07-17

    Here we report an aptamer-based analogue of the widely used sandwich enzyme-linked immunosorbent assay (ELISA). This assay utilizes the cocaine split aptamer, which is comprised of two DNA strands that only assemble in the presence of the target small molecule. One split aptamer fragment is immobilized on a microplate, then a test sample is added containing the second split aptamer fragment. If cocaine is present in the test sample, it directs assembly of the split aptamer and promotes a chemical ligation between azide and cyclooctyne functional groups appended to the termini of the split aptamer fragments. Ligation results in covalent attachment of biotin to the microplate and provides a colorimetric output upon conjugation to streptavidin-horseradish peroxidase. Using this assay, we demonstrate detection of cocaine at concentrations of 100 nM-100 μM in buffer and 1-100 μM human blood serum. The detection limit of 1 μM in serum represents an improvement of two orders of magnitude over previously reported split aptamer-based sensors and highlights the utility of covalently trapping split aptamer assembly events.

  5. Thermal management of liquid direct cooled split disk laser

    NASA Astrophysics Data System (ADS)

    Yang, Huomu; Feng, Guoying; Zhou, Shouhuan

    2015-02-01

    The thermal effects of a liquid direct cooled split disk laser are modeled and analytically solved. The analytical solutions with the consideration of longitudinal cooling liquid temperature rise have been given to describe the temperature distribution in the split disk and cooling liquid based on the hydrodynamics and heat transfer. The influence of cooling liquid, liquid flowing velocity, thickness of cooling channel and of disk gain medium can also be got from the analytical solutions.

  6. Electronic spectrum of trilayer graphene

    NASA Astrophysics Data System (ADS)

    Kumar, S.; Ajay

    2014-08-01

    Present work deals with the analysis of the single particle electronic spectral function in trilayer (ABC-, ABA- and AAA-stacked) graphene. Tight binding Hamiltonian containing intralayer nearest-neighbor and next-nearest neighbor hopping along-with the interlayer coupling parameter within two triangular sub-lattice approach for trilayer graphene has been employed. The expression of single particle spectral functions A(kw) is obtained within mean-field Green's function equations of motion approach. Spectral function at Γ, M and K points of the Brillouin zone has been numerically computed. It is pointed out that the nature of electronic states at different points of Brillouin zone is found to be influenced by stacking order and Coulomb interactions. At Γ and M points, a trilayer splitting is predicted while at K point a bilayer splitting effect is observed due to crossing of two bands (at K point). Interlayer coupling ( t_{ bot } ) is found to be responsible for the splitting of quasi-particle peaks at each point of Brillouin zone. The influence of t_{ bot } in trilayer graphene is prominent for AAA-stacking compared to ABC- and ABA-stacking. On the other hand, onsite Coulomb interaction reduces the trilayer splitting effect into bilayer splitting at Γ and M points of Brillouin zone and bilayer splitting into single peak spectral function at K point with a shifting of the peak away from Fermi level.

  7. Microcracking, microcrack-induced delamination, and longitudinal splitting of advanced composite structures

    NASA Technical Reports Server (NTRS)

    Nairn, John A.

    1992-01-01

    A combined analytical and experimental study was conducted to analyze microcracking, microcrack-induced delamination, and longitudinal splitting in polymer matrix composites. Strain energy release rates, calculated by a variational analysis, were used in a failure criterion to predict microcracking. Predictions and test results were compared for static, fatigue, and cyclic thermal loading. The longitudinal splitting analysis accounted for the effects of fiber bridging. Test data are analyzed and compared for longitudinal splitting and delamination under mixed-mode loading. This study emphasizes the importance of using fracture mechanics analyses to understand the complex failure processes that govern composite strength and life.

  8. Choice of implicit and explicit operators for the upwind differencing method

    NASA Technical Reports Server (NTRS)

    Liou, Meng-Sing; Vanleer, Bram

    1988-01-01

    The flux-vector and flux-difference splittings of Steger-Warming, van Leer and Roe are tested in all possible combinations on the implicit and explicit operators that can be distinguished in implicit relaxation methods for the steady Euler and Navier-Stokes equations. The tests include one-dimensional inviscid nozzle flow, and two-dimensional inviscid and viscous shock reflection. Roe's splitting, as anticipated, is found to uniformly yield the most accurate results. On the other hand, an approximate Roe splitting of the implicit operator (the complete Roe splitting is too complicated for practical use) proves to be the least robust with regard to convergence to the steady state. In this respect, the Steger-Warming splitting is the most robust; it leads to convergence when combined with any of the splittings in the explicit operator, although not necessarily in the most efficient way.

  9. Compressive Strength of Notched Poly(Phenylene Sulfide) Aerospace Composite: Influence of Fatigue and Environment

    NASA Astrophysics Data System (ADS)

    Niitsu, G. T.; Lopes, C. M. A.

    2013-08-01

    The purpose of this work is to evaluate the influences of fatigue and environmental conditions (-55 °C, 23 °C, and 82 °C/Wet) on the ultimate compression strength of notched carbon-fiber-reinforced poly(phenylene sulfide) composites by performing open-hole compression (OHC) tests. Analysis of the fatigue effect showed that at temperatures of -55 and 23 °C, the ultimate OHC strengths were higher for fatigued than for not-fatigued specimens; this could be attributed to fiber splitting and delamination during fatigue cycling, which reduces the stress concentration at the hole edge, thus increasing the composite strength. This effect of increasing strength for fatigued specimens was not observed under the 82 °C/Wet conditions, since the test temperature near the matrix glass transition temperature ( T g) together with moisture content resulted in matrix softening, suggesting a reduction in fiber splitting during cycling; similar OHC strengths were verified for fatigued and not-fatigued specimens tested at 82 °C/Wet. Analysis of the temperature effect showed that the ultimate OHC strengths decreased with increasing temperature. A high temperature together with moisture content (82 °C/Wet condition) reduced the composite compressive strengths, since a temperature close to the matrix T g resulted in matrix softening, which reduced the lateral support provided by the resin to the 0° fibers, leading to fiber instability failure at reduced applied loads. On the other hand, a low temperature (-55 °C) improved the compressive strength because of possible fiber-matrix interfacial strengthening, increasing the fiber contribution to compressive strength.

  10. Healing the mind/body split: bringing the patient back into oncology.

    PubMed

    Greer, Steven

    2003-03-01

    The effect on oncology of the doctrine of Cartesian dualism is examined. It is argued that (1) this doctrine continues to exert a baneful (though unacknowledged) influence on the practice of oncology, (2) Descartes's doctrine of a mind/body split is mistaken, and (3) mind and body (brain) are inextricably interwoven. A biopsychosocial model of disease is advocated. The role of psychooncology in healing the mind/body split by focusing research attention on the patient is outlined.

  11. Relative motions of fragments of the split comets. III - A test of splitting and comets with suspected multiple nuclei

    NASA Technical Reports Server (NTRS)

    Sekanina, Z.

    1979-01-01

    A quantitative test of splitting for comets with suspected multiple nuclei has been formulated using a model which assumes the motions of cometary fragments to be due primarily to outgassing. The model expresses the relative motion of the cometary fragments in terms of the time of splitting and the differential force, which are determined by measurements of the position angle and the separation distance between fragments. The test is applied to 18 comets suspected of having multiple nuclei, of which the comets Sawerthal 1888 I, Campbell 1914 IV, Whipple-Fedtke-Tevzadze 1943 I, Honda 1955 V, Wild 1968 III and Tago-Sato-Kosaka 1969 IX were found to be clear cases of split comets and Davidson 1889 IV and Periodic Giacobini 1896 V were judged to be likely candidates. At least three of the secondary nuclei confirmed can be classified as short-lived companions, while only two appear to be persistent.

  12. Delamination Fracture Related to Tempering in a High-Strength Low-Alloy Steel

    NASA Astrophysics Data System (ADS)

    Yan, Wei; Sha, Wei; Zhu, Lin; Wang, Wei; Shan, Yi-Yin; Yang, Ke

    2010-01-01

    The delamination or splitting of mechanical test specimens of rolled steel plate is a phenomenon that has been studied for many years. In the present study, splitting during fracture of tensile and Charpy V-notch (CVN) test specimens is examined in a high-strength low-alloy plate steel. It is shown that delamination did not occur in test specimens from plate in the as-rolled condition, but was severe in material tempered in the temperature range 500 °C to 650 °C. Minor splitting was seen after heating to 200 °C, 400 °C, and 700 °C. Samples that had been triple quenched and tempered to produce a fine equiaxed grain size also did not exhibit splitting. Microstructural and preferred orientation studies are presented and are discussed as they relate to the splitting phenomenon. It is concluded that the elongated as-rolled grains and grain boundary embrittlement resulting from precipitates (carbides and nitrides) formed during reheating were responsible for the delamination.

  13. 10 CFR 26.165 - Testing split specimens and retesting single specimens.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Testing split specimens and retesting single specimens. 26.165 Section 26.165 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Laboratories... laboratory or maintained in secure storage at the licensee testing facility, as required by § 26.135(a) and...

  14. Dose Uniformity of Scored and Unscored Tablets: Application of the FDA Tablet Scoring Guidance for Industry.

    PubMed

    Ciavarella, Anthony B; Khan, Mansoor A; Gupta, Abhay; Faustino, Patrick J

    This U.S. Food and Drug Administration (FDA) laboratory study examines the impact of tablet splitting, the effect of tablet splitters, and the presence of a tablet score on the dose uniformity of two model drugs. Whole tablets were purchased from five manufacturers for amlodipine and six for gabapentin. Two splitters were used for each drug product, and the gabapentin tablets were also split by hand. Whole and split amlodipine tablets were tested for content uniformity following the general chapter of the United States Pharmacopeia (USP) Uniformity of Dosage Units <905>, which is a requirement of the new FDA Guidance for Industry on tablet scoring. The USP weight variation method was used for gabapentin split tablets based on the recommendation of the guidance. All whole tablets met the USP acceptance criteria for the Uniformity of Dosage Units. Variation in whole tablet content ranged from 0.5 to 2.1 standard deviation (SD) of the percent label claim. Splitting the unscored amlodipine tablets resulted in a significant increase in dose variability of 6.5-25.4 SD when compared to whole tablets. Split tablets from all amlodipine drug products did not meet the USP acceptance criteria for content uniformity. Variation in the weight for gabapentin split tablets was greater than the whole tablets, ranging from 1.3 to 9.3 SD. All fully scored gabapentin products met the USP acceptance criteria for weight variation. Size, shape, and the presence or absence of a tablet score can affect the content uniformity and weight variation of amlodipine and gabapentin tablets. Tablet splitting produced higher variability. Differences in dose variability and fragmentation were observed between tablet splitters and hand splitting. These results are consistent with the FDA's concerns that tablet splitting can have an effect on the amount of drug present in a split tablet and available for absorption. Tablet splitting has become a very common practice in the United States and throughout the world. Tablets are often split to modify dose strength, make swallowing easier, and reduce cost to the consumer. To better address product quality for this widely used practice, the U.S. Food and Drug Administration (FDA) published a Guidance for Industry that addresses tablet splitting. The guidance provides testing criteria for scored tablets, which is a part of the FDA review process for drugs. The model drugs selected for this study were amlodipine and gabapentin, which have different sizes, shapes, and tablet scores. Whole and split amlodipine tablets were tested for drug content because of a concern that the low-dose strength may cause greater variability. Whole and split gabapentin tablets were tested for weight variation because of their higher dosage strength of 600 mg. All whole tablets met the acceptance criteria for the Uniformity of Dosage Units based on the guidance recommendations. When unscored amlodipine tablets were split by a splitter, all formulations did not meet the acceptance criteria. When fully scored gabapentin tablets were split by hand and by splitter, they met the acceptance criteria. The findings of this FDA study indicated physical characteristics such as size, shape, and tablet score can affect the uniformity of split tablets. © PDA, Inc. 2016.

  15. Evaluation of workability and strength of green concrete using waste steel scrap

    NASA Astrophysics Data System (ADS)

    Neeraja, D.; Arshad, Shaik Mohammed; Nawaz Nadaf, Alisha K.; Reddy, Mani Kumar

    2017-11-01

    This project works on the study of workability and mechanical properties of concrete using waste steel scrap from the lathe industry. Lathe industries produce waste steel scrap from the lathe machines. In this study, an attempt is made to use this waste in concrete, as accumulation of waste steel scrap cause disposal problem. Tests like compressive test, split tensile test, NDT test (UPV test) were conducted to determine the impact of steel scrap in concrete. The percentages of steel scrap considered in the study were 0%, 0.5%, 1%, 1.5%, and 2% respectively by volume of concrete, 7 day, 28 days test were conducted to find out strength of steel scrap concrete. It is observed that split tensile strength of steel scrap concrete is increased slightly. Split tensile strength of Steel scrap concrete is found to be maximum with volume fraction of 2.0% steel scrap. The steel scrap gives good result in split tensile strength of concrete. From the study concluded that steel scrap can be used in concrete to reduce brittleness of concrete to some extent.

  16. Excitonic fine-structure splitting in telecom-wavelength InAs/GaAs quantum dots: Statistical distribution and height-dependence

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goldmann, Elias, E-mail: goldmann@itp.uni-bremen.de; Barthel, Stefan; Florian, Matthias

    The variation of the excitonic fine-structure splitting is studied for semiconductor quantum dots under the influence of a strain-reducing layer, utilized to shift the emission wavelength of the excitonic transition into the telecom-wavelength regime of 1.3–1.5 μm. By means of a sp{sup 3}s{sup *}-tight-binding model and configuration interaction, we calculate wavelength shifts and fine-structure splittings for various quantum dot geometries. We find the splittings remaining small and even decreasing with strain-reducing layer composition for quantum dots with large height. Combined with an observed increased emission efficiency, the applicability for generation of entanglement photons is persistent.

  17. Three-dimensional multigrid algorithms for the flux-split Euler equations

    NASA Technical Reports Server (NTRS)

    Anderson, W. Kyle; Thomas, James L.; Whitfield, David L.

    1988-01-01

    The Full Approximation Scheme (FAS) multigrid method is applied to several implicit flux-split algorithms for solving the three-dimensional Euler equations in a body fitted coordinate system. Each of the splitting algorithms uses a variation of approximate factorization and is implemented in a finite volume formulation. The algorithms are all vectorizable with little or no scalar computation required. The flux vectors are split into upwind components using both the splittings of Steger-Warming and Van Leer. The stability and smoothing rate of each of the schemes are examined using a Fourier analysis of the complete system of equations. Results are presented for three-dimensional subsonic, transonic, and supersonic flows which demonstrate substantially improved convergence rates with the multigrid algorithm. The influence of using both a V-cycle and a W-cycle on the convergence is examined.

  18. Tablet splitting: a review of the clinical and economic outcomes and patient acceptance. Second of a 2-part series. Part 1 was published in May 2012 (Consult Pharm 2012;27:239-53).

    PubMed

    Freeman, Maisha Kelly; White, Whitney; Iranikhah, Maryam

    2012-06-01

    To describe the clinical outcomes, patient acceptance, and economic effect associated with tablet splitting. PubMed (1966-June 2011) and International Pharmaceutical Abstract (1975-June 2011) searches were conducted using tablet splitting as the search terms. All studies that evaluated the clinical outcome (n = 4), patient acceptance (n = 5), and economic effects (n = 8) of tablet splitting were included. The American Pharmacists Association guidelines, recommendations from the Food and Drug Administration, and clinical trial data were evaluated. The majority of trials conducted evaluating clinical outcomes associated with tablet splitting were evaluated in patients receiving statins and antihypertensives. Clinical outcomes associated with risperidone were assessed. No adverse clinical outcomes were observed with therapy. Most studies evaluating the economic effects of tablet splitting have revealed a cost savings associated with this process; however, many studies were subject to limitations. The first part of this two-part series reviewed the weight and content uniformity in tablet splitting. Tablet splitting does not seem to significantly affect clinical outcomes related to management of hypertension, cholesterol, or psychiatric disorders, nor influence overall patient adherence.

  19. Influence of postoperative low-level laser therapy on the osseointegration of self-tapping implants in the posterior maxilla: a 6-week split-mouth clinical study.

    PubMed

    Mandić, Borka; Lazić, Zoran; Marković, Aleksa; Mandić, Bojan; Mandić, Miška; Djinić, Ana; Miličić, Biljana

    2015-03-01

    Low-level laser therapy (LLLT) has been proven to stimulate bone repair, affecting cellular proliferation, differentiation and adhesion, and has shown a potential to reduce the healing time following implant placement. The aim of this clinical study was to investigate the influence of postoperative LLLT osseointegration and early success of self-tapping implants placed into low-density bone. Following the split-mouth design, self-tapping implants n = 44) were inserted in the posterior maxilla of 12 patients. One jaw side randomly received LLLT (test group), while the other side was placebo (control group). For LLLT, a 637 nm gallium-aluminum-arsenide (GaAlAs) laser (Medicolaser 637, Technoline, Belgrade, Serbia) with an output power of 40 mW and continuous wave was used. Low-level laser treatment was performed immediately after the surgery and then repeated every day in the following 7 days. The total irradiation dose per treatment was 6.26 J/cm2 per implant. The study outcomes were: implant stability, alkaline-phosphatase (ALP) activity and early implant success rate. The follow-up took 6 weeks. Irradiated implants achieved a higher stability compared with controls during the entire follow-up and the difference reached significance in the 5th postoperative week (paired t-test, p = 0.030). The difference in ALP activity between the groups was insignificant in any observation point (paired t-test, p > 0.05). The early implant success rate was 100%, regardless of LLLT usage. LLLT applied daily during the first postoperative week expressed no significant influence on the osseointegration of self-tapping implants placed into low density bone of the posterior maxilla. Placement of self-tapping macro-designed implants into low density bone could be a predictable therapeutic procedure with a high early success rate regardless of LLLT usage.

  20. Relationship between mandibular anatomy and the occurrence of a bad split upon sagittal split osteotomy.

    PubMed

    Aarabi, Mohammadali; Tabrizi, Reza; Hekmat, Mina; Shahidi, Shoaleh; Puzesh, Ayatollah

    2014-12-01

    A bad split is a troublesome complication of the sagittal split osteotomy (SSO). The aim of this study was to evaluate the relation between the occurrence of a bad split and mandibular anatomy in SSO using cone-beam computed tomography. The authors designed a cohort retrospective study. Forty-eight patients (96 SSO sites) were studied. The buccolingual thickness of the retromandibular area (BLR), the buccolingual thickness of the ramus at the level of the lingula (BLTR), the height of the mandible from the alveolar crest to the inferior border of the mandible, (ACIB), the distance between the sigmoid notch and the inferior border of the mandible (SIBM), and the anteroposterior width of the ramus (APWR) were measured. The independent t test was applied to compare anatomic measurements between the group with and the group without bad splits. The receiver operating characteristic (ROC) test was used to find a cutoff point in anatomic size for various parts of the mandible related to the occurrence of bad splits. The mean SIBM was 47.05±6.33 mm in group 1 (with bad splits) versus 40.66±2.44 mm in group 2 (without bad splits; P=.01). The mean BLTR was 5.74±1.11 mm in group 1 versus 3.19±0.55 mm in group 2 (P=.04). The mean BLR was 14.98±2.78 mm in group 1 versus 11.21±1.29 mm in group 2 (P=.001). No statistically significant difference was found for APWR and ACIB between the 2 groups. The ROC test showed cutoff points of 10.17 mm for BLR, 36.69 mm for SIBM, and 4.06 mm for BLTR. This study showed that certain mandibular anatomic differences can increase the risk of a bad split during SSO surgery. Copyright © 2014 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  1. High-Strain-Rate Compression Testing of Ice

    NASA Technical Reports Server (NTRS)

    Shazly, Mostafa; Prakash, Vikas; Lerch, Bradley A.

    2006-01-01

    In the present study a modified split Hopkinson pressure bar (SHPB) was employed to study the effect of strain rate on the dynamic material response of ice. Disk-shaped ice specimens with flat, parallel end faces were either provided by Dartmouth College (Hanover, NH) or grown at Case Western Reserve University (Cleveland, OH). The SHPB was adapted to perform tests at high strain rates in the range 60 to 1400/s at test temperatures of -10 and -30 C. Experimental results showed that the strength of ice increases with increasing strain rates and this occurs over a change in strain rate of five orders of magnitude. Under these strain rate conditions the ice microstructure has a slight influence on the strength, but it is much less than the influence it has under quasi-static loading conditions. End constraint and frictional effects do not influence the compression tests like they do at slower strain rates, and therefore the diameter/thickness ratio of the samples is not as critical. The strength of ice at high strain rates was found to increase with decreasing test temperatures. Ice has been identified as a potential source of debris to impact the shuttle; data presented in this report can be used to validate and/or develop material models for ice impact analyses for shuttle Return to Flight efforts.

  2. Tests of Branch Splitting and Branch-Splitting Independence in Allais Paradoxes with Positive and Mixed Consequences

    ERIC Educational Resources Information Center

    Birnbaum, Michael H.

    2007-01-01

    Four experiments with 1391 participants compared descriptive models of risky decision making. The first replicated and extended evidence refuting cumulative prospect theory (CPT) as an explanation of Allais paradoxes. The second and third experiments used a new design to unconfound tests of upper and lower coalescing, which allows tests of…

  3. Bad splits in bilateral sagittal split osteotomy: systematic review and meta-analysis of reported risk factors.

    PubMed

    Steenen, S A; van Wijk, A J; Becking, A G

    2016-08-01

    An unfavourable and unanticipated pattern of the bilateral sagittal split osteotomy (BSSO) is generally referred to as a 'bad split'. Patient factors predictive of a bad split reported in the literature are controversial. Suggested risk factors are reviewed in this article. A systematic review was undertaken, yielding a total of 30 studies published between 1971 and 2015 reporting the incidence of bad split and patient age, and/or surgical technique employed, and/or the presence of third molars. These included 22 retrospective cohort studies, six prospective cohort studies, one matched-pair analysis, and one case series. Spearman's rank correlation showed a statistically significant but weak correlation between increasing average age and increasing occurrence of bad splits in 18 studies (ρ=0.229; P<0.01). No comparative studies were found that assessed the incidence of bad split among the different splitting techniques. A meta-analysis pooling the effect sizes of seven cohort studies showed no significant difference in the incidence of bad split between cohorts of patients with third molars present and concomitantly removed during surgery, and patients in whom third molars were removed at least 6 months preoperatively (odds ratio 1.16, 95% confidence interval 0.73-1.85, Z=0.64, P=0.52). In summary, there is no robust evidence to date to show that any risk factor influences the incidence of bad split. Copyright © 2016 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  4. 75 FR 38774 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... design research as part of testing for its censuses and surveys. At this time, the Census Bureau is... follows: Field test, Respondent debriefing questionnaire, Split sample experiments, Cognitive interviews... each round will be provided separately. When split sample experiments are conducted, either in small...

  5. Jump-Squat and Half-Squat Exercises: Selective Influences on Speed-Power Performance of Elite Rugby Sevens Players

    PubMed Central

    Loturco, Irineu; Pereira, Lucas A.; Moraes, José E.; Kitamura, Katia; Cal Abad, César C.; Kobal, Ronaldo; Nakamura, Fábio Y.

    2017-01-01

    The aim of this study was to evaluate the relation between the maximum mean propulsive power (MPP) obtained in the loaded jump squat (JS) and half squat (HS) exercises and functional performances in vertical jumps, 40 m linear speed (VEL) and change-of-direction (COD) tests, using the median split technique. Twenty-two male rugby sevens players from the Brazilian National Olympic Team (Rio-2016) performed vertical jumping tests (squat and countermovement jumps [SJ and CMJ]), JS and HS exercises, COD speed test and sprinting velocity in 40 m, in this order. Based on the results of the MPP in the JS and HS exercises the participants were divided, using the median split, into four groups as follows: higher JS, lower JS, higher HS, and lower HS. Between-group differences in the functional tasks were detected via magnitude-based inferences. The athletes with higher MPP in the JS were capable of jumping higher and sprinting faster (including the COD speed test) than their weaker counterparts. This pattern was not observed in the HS exercise. To conclude, JS was shown to be more connected to sprinting, COD speed and jumping abilities than HS in elite rugby sevens players and should be preferred for assessing and possibly training elite athletes needing to improve speed-power related abilities. PMID:28114431

  6. Jump-Squat and Half-Squat Exercises: Selective Influences on Speed-Power Performance of Elite Rugby Sevens Players.

    PubMed

    Loturco, Irineu; Pereira, Lucas A; Moraes, José E; Kitamura, Katia; Cal Abad, César C; Kobal, Ronaldo; Nakamura, Fábio Y

    2017-01-01

    The aim of this study was to evaluate the relation between the maximum mean propulsive power (MPP) obtained in the loaded jump squat (JS) and half squat (HS) exercises and functional performances in vertical jumps, 40 m linear speed (VEL) and change-of-direction (COD) tests, using the median split technique. Twenty-two male rugby sevens players from the Brazilian National Olympic Team (Rio-2016) performed vertical jumping tests (squat and countermovement jumps [SJ and CMJ]), JS and HS exercises, COD speed test and sprinting velocity in 40 m, in this order. Based on the results of the MPP in the JS and HS exercises the participants were divided, using the median split, into four groups as follows: higher JS, lower JS, higher HS, and lower HS. Between-group differences in the functional tasks were detected via magnitude-based inferences. The athletes with higher MPP in the JS were capable of jumping higher and sprinting faster (including the COD speed test) than their weaker counterparts. This pattern was not observed in the HS exercise. To conclude, JS was shown to be more connected to sprinting, COD speed and jumping abilities than HS in elite rugby sevens players and should be preferred for assessing and possibly training elite athletes needing to improve speed-power related abilities.

  7. Sikorsky Aircraft Advanced Rotorcraft Transmission (ART) program

    NASA Technical Reports Server (NTRS)

    Kish, Jules G.

    1993-01-01

    The objectives of the Advanced Rotorcraft Transmission program were to achieve a 25 percent weight reduction, a 10 dB noise reduction, and a 5,000 hour mean time between removals (MTBR). A three engine Army Cargo Aircraft (ACA) of 85,000 pounds gross weight was used as the baseline. Preliminary designs were conducted of split path and split torque transmissions to evaluate weight, reliability, and noise. A split path gearbox was determined to be 23 percent lighter, greater than 10 dB quieter, and almost four times more reliable than the baseline two stage planetary design. Detail design studies were conducted of the chosen split path configuration, and drawings were produced of a 1/2 size gearbox consisting of a single engine path of the split path section. Fabrication and testing was then conducted on the 1/2 size gearbox. The 1/2 size gearbox testing proved that the concept of the split path gearbox with high reduction ratio double helical output gear was sound. The improvements were attributed to extensive use of composites, spring clutches, advanced high hot hardness gear steels, the split path configuration itself, high reduction ratio, double helical gearing on the output stage, elastomeric load sharing devices, and elimination of accessory drives.

  8. What Contributes to the Split-Attention Effect? The Role of Text Segmentation, Picture Labelling, and Spatial Proximity

    ERIC Educational Resources Information Center

    Florax, Mareike; Ploetzner, Rolf

    2010-01-01

    In the split-attention effect spatial proximity is frequently considered to be pivotal. The transition from a spatially separated to a spatially integrated format not only involves changes in spatial proximity, but commonly necessitates text segmentation and picture labelling as well. In an experimental study, we investigated the influence of…

  9. A survey of upwind methods for flows with equilibrium and non-equilibrium chemistry and thermodynamics

    NASA Technical Reports Server (NTRS)

    Grossman, B.; Garrett, J.; Cinnella, P.

    1989-01-01

    Several versions of flux-vector split and flux-difference split algorithms were compared with regard to general applicability and complexity. Test computations were performed using curve-fit equilibrium air chemistry for an M = 5 high-temperature inviscid flow over a wedge, and an M = 24.5 inviscid flow over a blunt cylinder for test computations; for these cases, little difference in accuracy was found among the versions of the same flux-split algorithm. For flows with nonequilibrium chemistry, the effects of the thermodynamic model on the development of flux-vector split and flux-difference split algorithms were investigated using an equilibrium model, a general nonequilibrium model, and a simplified model based on vibrational relaxation. Several numerical examples are presented, including nonequilibrium air chemistry in a high-temperature shock tube and nonequilibrium hydrogen-air chemistry in a supersonic diffuser.

  10. Quality and safety of red blood cells stored in two additive solutions subjected to multiple room temperature exposures.

    PubMed

    de Grandmont, M J; Ducas, E; Girard, M; Méthot, M; Brien, M; Thibault, L

    2014-10-01

    Many international standards state that red blood cell (RBC) products should be discarded if left out of controlled temperature storage for longer than 30 min to reduce the risk of bacterial growth and RBC loss of viability. This study aimed to verify whether repeated short-time exposures to room temperature (RT) influence RBCs quality and bacterial proliferation. Saline-adenine-glucose-mannitol (SAGM) and AS-3 RBC units were split and exposed to RT for 30 or 60 min on day 2, 7, 14, 21, and 42 of storage while reference units remained stored at 1-6°C. Red blood cell in vitro quality parameters were evaluated after each exposure. In a second experiment, SAGM and AS-3 RBC units were split and inoculated with Staphylococcus epidermidis (5 CFU/ml), Serratia marcescens (1 CFU/ml), and Serratia liquefaciens (1 CFU/ml). Reference units remained in storage while test units were exposed as described previously. Bacterial concentrations were investigated after each exposure. No differences were noticed between reference and test units in any of the in vitro parameters investigated. S. epidermidis did not grow in either reference or exposed RBCs. While S. marcescens did not grow in AS-3, bacterial growth was observed in RT-exposed SAGM RBCs on day 42. Similar growth was obtained for S. liquefaciens in the two additive solutions for both reference and test units. Short-time exposures to RT do not affect RBC quality and do not significantly influence bacterial growth. An expansion of the '30-minute' rule to 60 min should be considered by regulatory agencies. © 2014 International Society of Blood Transfusion.

  11. 49 CFR 40.173 - Who is responsible for paying for the test of a split specimen?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... is responsible for paying for the test of a split specimen? (a) As the employer, you are responsible... 49 Transportation 1 2010-10-01 2010-10-01 false Who is responsible for paying for the test of a.... (b) As the employer, you must not condition your compliance with these requirements on the employee's...

  12. Influence of Controlled Viscous Dissipation on Propagation of Strongly Nonlinear Waves in Steel-Based Phononic Crystals

    NASA Astrophysics Data System (ADS)

    Herbold, Eric

    2005-07-01

    Strongly nonlinear phononic crystals were assembled from chains of stainless steel spheres with diameter 4.78 mm. Propagation of solitary waves and splitting of initial pulse into train of solitary waves excited by the impact of piston was investigated in different viscous media in experiments and in numerical calculations. Oil of various grades was used to introduce controlled dissipation into the system. Preliminary results indicate that splitting of the initial pulse into the train of solitary waves was dramatically influenced by viscosity. This work was supported by NSF (Grant No. DCMS03013220).

  13. Quantifying kinematic differences between land and water during squats, split squats, and single-leg squats in a healthy population.

    PubMed

    Severin, Anna C; Burkett, Brendan J; McKean, Mark R; Wiegand, Aaron N; Sayers, Mark G L

    2017-01-01

    Aquatic exercises can be used in clinical and sporting disciplines for both rehabilitation and sports training. However, there is limited knowledge on the influence of water immersion on the kinematics of exercises commonly used in rehabilitation and fitness programs. The aim of this study was to use inertial sensors to quantify differences in kinematics and movement variability of bodyweight squats, split squats, and single-leg squats performed on dry land and whilst immersed to the level of the greater trochanter. During two separate testing sessions, 25 active healthy university students (22.3±2.9 yr.) performed ten repetitions of each exercise, whilst tri-axial inertial sensors (100 Hz) recorded their trunk and lower body kinematics. Repeated-measures statistics tested for differences in segment orientation and speed, movement variability, and waveform patterns between environments, while coefficient of variance was used to assess differences in movement variability. Between-environment differences in segment orientation and speed were portrayed by plotting the mean difference ±95% confidence intervals (CI) throughout the tasks. The results showed that the depth of the squat and split squat were unaffected by the changed environment while water immersion allowed for a deeper single leg squat. The different environments had significant effects on the sagittal plane orientations and speeds for all segments. Water immersion increased the degree of movement variability of the segments in all exercises, except for the shank in the frontal plane, which showed more variability on land. Without compromising movement depth, the aquatic environment induces more upright trunk and shank postures during squats and split squats. The aquatic environment allows for increased squat depth during the single-leg squat, and increased shank motions in the frontal plane. Our observations therefore support the use of water-based squat tasks for rehabilitation as they appear to improve the technique without compromising movement depth.

  14. Quantifying kinematic differences between land and water during squats, split squats, and single-leg squats in a healthy population

    PubMed Central

    2017-01-01

    Aquatic exercises can be used in clinical and sporting disciplines for both rehabilitation and sports training. However, there is limited knowledge on the influence of water immersion on the kinematics of exercises commonly used in rehabilitation and fitness programs. The aim of this study was to use inertial sensors to quantify differences in kinematics and movement variability of bodyweight squats, split squats, and single-leg squats performed on dry land and whilst immersed to the level of the greater trochanter. During two separate testing sessions, 25 active healthy university students (22.3±2.9 yr.) performed ten repetitions of each exercise, whilst tri-axial inertial sensors (100 Hz) recorded their trunk and lower body kinematics. Repeated-measures statistics tested for differences in segment orientation and speed, movement variability, and waveform patterns between environments, while coefficient of variance was used to assess differences in movement variability. Between-environment differences in segment orientation and speed were portrayed by plotting the mean difference ±95% confidence intervals (CI) throughout the tasks. The results showed that the depth of the squat and split squat were unaffected by the changed environment while water immersion allowed for a deeper single leg squat. The different environments had significant effects on the sagittal plane orientations and speeds for all segments. Water immersion increased the degree of movement variability of the segments in all exercises, except for the shank in the frontal plane, which showed more variability on land. Without compromising movement depth, the aquatic environment induces more upright trunk and shank postures during squats and split squats. The aquatic environment allows for increased squat depth during the single-leg squat, and increased shank motions in the frontal plane. Our observations therefore support the use of water-based squat tasks for rehabilitation as they appear to improve the technique without compromising movement depth. PMID:28767683

  15. Divided spatial attention and feature-mixing errors.

    PubMed

    Golomb, Julie D

    2015-11-01

    Spatial attention is thought to play a critical role in feature binding. However, often multiple objects or locations are of interest in our environment, and we need to shift or split attention between them. Recent evidence has demonstrated that shifting and splitting spatial attention results in different types of feature-binding errors. In particular, when two locations are simultaneously sharing attentional resources, subjects are susceptible to feature-mixing errors; that is, they tend to report a color that is a subtle blend of the target color and the color at the other attended location. The present study was designed to test whether these feature-mixing errors are influenced by target-distractor similarity. Subjects were cued to split attention across two different spatial locations, and were subsequently presented with an array of colored stimuli, followed by a postcue indicating which color to report. Target-distractor similarity was manipulated by varying the distance in color space between the two attended stimuli. Probabilistic modeling in all cases revealed shifts in the response distribution consistent with feature-mixing errors; however, the patterns differed considerably across target-distractor color distances. With large differences in color, the findings replicated the mixing result, but with small color differences, repulsion was instead observed, with the reported target color shifted away from the other attended color.

  16. Numerical simulation and experiment on multilayer stagger-split die.

    PubMed

    Liu, Zhiwei; Li, Mingzhe; Han, Qigang; Yang, Yunfei; Wang, Bolong; Sui, Zhou

    2013-05-01

    A novel ultra-high pressure device, multilayer stagger-split die, has been constructed based on the principle of "dividing dies before cracking." Multilayer stagger-split die includes an encircling ring and multilayer assemblages, and the mating surfaces of the multilayer assemblages are mutually staggered between adjacent layers. In this paper, we investigated the stressing features of this structure through finite element techniques, and the results were compared with those of the belt type die and single split die. The contrast experiments were also carried out to test the bearing pressure performance of multilayer stagger-split die. It is concluded that the stress distributions are reasonable and the materials are utilized effectively for multilayer stagger-split die. And experiments indicate that the multilayer stagger-split die can bear the greatest pressure.

  17. Small Payload Integration and Testing Project Development

    NASA Technical Reports Server (NTRS)

    Sorenson, Tait R.

    2014-01-01

    The National Aeronautics and Space Administration's (NASA) Kennedy Space Center (KSC) has mainly focused on large payloads for space flight beginning with the Apollo program to the assembly and resupply of the International Space Station using the Space Shuttle. NASA KSC is currently working on contracting manned Low Earth Orbit (LEO) to commercial providers, developing Space Launch System, the Orion program, deep space manned programs which could reach Mars, and providing technical expertise for the Launch Services Program for science mission payloads/satellites. KSC has always supported secondary payloads and smaller satellites as the launch provider; however, they are beginning to take a more active role in integrating and testing secondary payloads into future flight opportunities. A new line of business, the Small Payload Integration and Testing Services (SPLITS), has been established to provide a one stop shop that can integrate and test payloads. SPLITS will assist high schools, universities, companies and consortiums interested in testing or launching small payloads. The goal of SPLITS is to simplify and facilitate access to KSC's expertise and capabilities for small payloads integration and testing and to help grow the space industry. An effort exists at Kennedy Space Center to improve the external KSC website. External services has partnered with SPLITS as a content test bed for attracting prospective customers. SPLITS is an emerging effort that coincides with the relaunch of the website and has a goal of attracting external partnerships. This website will be a "front door" access point for all potential partners as it will contain an overview of KSC's services, expertise and includes the pertinent contact information.

  18. Precision sizing of moving large particles using diffraction splitting of Doppler lines

    NASA Astrophysics Data System (ADS)

    Kononenko, Vadim L.

    1999-02-01

    It is shown, that the Doppler line from a single large particle moving with a constant velocity through a finite- width laser beam, undergoes a doublet-type splitting under specific observation conditions. A general requirement is that particle size 2a is not negligibly small, compared with beam diameter 2w$0. Three optical mechanisms of line splitting are considered. The first one is based on nonsymmetric diffraction of a bounded laser beam by a moving particle. The second arises from the transient geometry of diffraction. The third mechanism, of photometric nature, originates from specific time variation of total illuminance of moving particles when 2a>Lambda, the interference fringe spacing in the measuring volume. The diffraction splitting is observed when a detector is placed near one of diffraction minima corresponding to either of probing beams, and 2a equals (n0.5)Lambda for n equals 1,2. The photometric splitting is observed with an image-forming optics, when 2a equals n(Lambda) . That gives the possibility of distant particles sizing based on the Doppler line splitting phenomenon. A general theory of line splitting is developed, and used to explain the experimental observations quantitatively. The influence of the scattering angels and observation angle on the line splitting characteristics is studied analytically and numerically.

  19. Stress distribution and pressure-bearing capacity of a high-pressure split-cylinder die with prism cavity

    NASA Astrophysics Data System (ADS)

    Zhao, Liang; Li, Mingzhe; Wang, Liyan; Qu, Erhu; Yi, Zhuo

    2018-03-01

    A novel high-pressure belt-type die with a split-type cylinder is investigated with respect to extending its lifetime and improving its pressure bearing capacity. Specifically, a tungsten carbide cylinder is split into several parts along the radial direction with a prism-type cavity. In this paper, the cylinders with different split numbers are chosen to study the stress distribution and compare them with the traditional belt-type die. The simulation results indicate that the split cylinder has much smaller stress than those in the belt-type cylinder, and the statistical analysis reveals that the split-pressure cylinder is able to bear higher pressure. Experimental tests also show that the high-pressure die with a split cylinder and prism cavity has a stronger pressure-bearing capacity than a belt-type die. The split cylinder has advantages of easy manufacturing, high pressure bearing capacity, and replaceable performance.

  20. Split-shift work in relation to stress, health and psychosocial work factors among bus drivers.

    PubMed

    Ihlström, Jonas; Kecklund, Göran; Anund, Anna

    2017-01-01

    Shift work has been associated with poor health, sleep and fatigue problems and low satisfaction with working hours. However, one type of shift working, namely split shifts, have received little attention. This study examined stress, health and psychosocial aspects of split-shift schedules among bus drivers in urban transport. A questionnaire was distributed to drivers working more than 70% of full time which 235 drivers in total answered. In general, drivers working split-shift schedules (n = 146) did not differ from drivers not working such shifts (n = 83) as regards any of the outcome variables that were studied. However, when individual perceptions towards split-shift schedules were taken into account, a different picture appeared. Bus drivers who reported problems working split shifts (36%) reported poorer health, higher perceived stress, working hours interfering with social life, lower sleep quality, more persistent fatigue and lower general work satisfaction than those who did not view split shifts as a problem. Moreover, drivers who reported problems with split shifts also perceived lower possibilities to influence working hours, indicating lower work time control. This study indicates that split shifts were not associated with increased stress, poorer health and adverse psychosocial work factors for the entire study sample. However, the results showed that individual differences were important and approximately one third of the drivers reported problems with split shifts, which in turn was associated with stress, poor health and negative psychosocial work conditions. More research is needed to understand the individual and organizational determinants of tolerance to split shifts.

  1. Stocking rate and fuels reduction effects on beef cattle diet composition and quality

    Treesearch

    Abe Clark; Tim DelCurto; Martin Vavra; Brian L. Dick

    2013-01-01

    An experiment was conducted to evaluate the influence of forest fuels reduction on diet quality, botanical composition, relative preference, and foraging efficiency of beef cattle grazing at different stocking rates. A split plot factorial design was used, with whole plots (3 ha) being fuel reduced or no treatment (control), and split plots (1 ha) within whole plots...

  2. Wind-tunnel research comparing lateral control devices, particularly at high angles of attack XII : upper-surface ailerons on wings with split flaps

    NASA Technical Reports Server (NTRS)

    Weick, Fred E; Wenzinger, Carl J

    1935-01-01

    This report covers the twelfth of a series of tests conducted to compare different lateral control devices with particular reference to their effectiveness at high angles of attack. The present wind tunnel tests were made with two sizes of upper-surface ailerons on rectangular Clark Y wing models equipped with full span split flaps. The tests showed the effect of the upper-surface ailerons and of the split flaps on the general performance characteristics of the wings, and on the lateral controllability and stability characteristics. The results are compared with those for plain wings with ordinary ailerons of similar sizes.

  3. Changes in the midpalatal and pterygopalatine sutures induced by micro-implant-supported skeletal expander, analyzed with a novel 3D method based on CBCT imaging.

    PubMed

    Cantarella, Daniele; Dominguez-Mompell, Ramon; Mallya, Sanjay M; Moschik, Christoph; Pan, Hsin Chuan; Miller, Joseph; Moon, Won

    2017-11-01

    Mini-implant-assisted rapid palatal expansion (MARPE) appliances have been developed with the aim to enhance the orthopedic effect induced by rapid maxillary expansion (RME). Maxillary Skeletal Expander (MSE) is a particular type of MARPE appliance characterized by the presence of four mini-implants positioned in the posterior part of the palate with bi-cortical engagement. The aim of the present study is to evaluate the MSE effects on the midpalatal and pterygopalatine sutures in late adolescents, using high-resolution CBCT. Specific aims are to define the magnitude and sagittal parallelism of midpalatal suture opening, to measure the extent of transverse asymmetry of split, and to illustrate the possibility of splitting the pterygopalatine suture. Fifteen subjects (mean age of 17.2 years; range, 13.9-26.2 years) were treated with MSE. Pre- and post-treatment CBCT exams were taken and superimposed. A novel methodology based on three new reference planes was utilized to analyze the sutural changes. Parameters were compared from pre- to post-treatment and between genders non-parametrically using the Wilcoxon sign rank test. For the frequency of openings in the lower part of the pterygopalatine suture, the Fisher's exact test was used. Regarding the magnitude of midpalatal suture opening, the split at anterior nasal spine (ANS) and at posterior nasal spine (PNS) was 4.8 and 4.3 mm, respectively. The amount of split at PNS was 90% of that at ANS, showing that the opening of the midpalatal suture was almost perfectly parallel antero-posteriorly. On average, one half of the anterior nasal spine (ANS) moved more than the contralateral one by 1.1 mm. Openings between the lateral and medial plates of the pterygoid process were detectable in 53% of the sutures (P < 0.05). No significant differences were found in the magnitude and frequency of suture opening between males and females. Correlation between age and suture opening was negligible (R 2 range, 0.3-4.2%). Midpalatal suture was successfully split by MSE in late adolescents, and the opening was almost perfectly parallel in a sagittal direction. Regarding the extent of transverse asymmetry of the split, on average one half of ANS moved more than the contralateral one by 1.1 mm. Pterygopalatine suture was split in its lower region by MSE, as the pyramidal process was pulled out from the pterygoid process. Patient gender and age had a negligible influence on suture opening for the age group considered in the study.

  4. An Intuitive Graphical Approach to Understanding the Split-Plot Experiment

    ERIC Educational Resources Information Center

    Robinson, Timothy J.; Brenneman, William A.; Myers, William R.

    2009-01-01

    While split-plot designs have received considerable attention in the literature over the past decade, there seems to be a general lack of intuitive understanding of the error structure of these designs and the resulting statistical analysis. Typically, students learn the proper error terms for testing factors of a split-plot design via "expected…

  5. What plant and soil testing from 16 sites in eight midwestern states tells us about split nitrogen applications

    USDA-ARS?s Scientific Manuscript database

    It is hypothesized that split-nitrogen (N) relative to single near-planting applications improve corn (Zea mays L.) production, N recovery efficiency, and lessen environmental impacts of fertilization. However, these hypotheses have not been fully tested. A 16-site study across eight US Midwestern s...

  6. An Investigation of Sample Size Splitting on ATFIND and DIMTEST

    ERIC Educational Resources Information Center

    Socha, Alan; DeMars, Christine E.

    2013-01-01

    Modeling multidimensional test data with a unidimensional model can result in serious statistical errors, such as bias in item parameter estimates. Many methods exist for assessing the dimensionality of a test. The current study focused on DIMTEST. Using simulated data, the effects of sample size splitting for use with the ATFIND procedure for…

  7. Comparison of torsional stability of 2 types of split crimpable surgical hooks with soldered brass surgical hooks.

    PubMed

    O'Bannon, Shawn P; Dunn, William J; Lenk, Jason S

    2006-10-01

    The purpose of this in-vitro study was to compare the torsional stability of split crimpable surgical hooks and soldered brass surgical hooks on a rectangular stabilizing archwire. Coated split crimpable hooks (Never-Slip Grip, TP Orthodontics, LaPorte, Ind), ribbed crimpable hooks (TP Orthodontics), and .032-in brass soldered hooks/notched electrodes (Ormco/Sybron Dental Specialties, Orange, Calif) were attached to a 0.019 x 0.025-in stainless steel archwire. The archwire/hook attachment assembly was secured into a dual contact jig and statically mounted to the base of a universal testing machine. The hooks were engaged by a wire loop attached to the upper load cell of the machine, which pulled the wire until the hook was torsionally displaced from the archwire. The mean forces, measured in newtons (N), required to dislodge the hooks were as follows: soldered brass surgical hooks (51.3 +/- 5.2 N), coated split crimpable hooks (49.9 +/- 6.6 N), and ribbed split crimpable hooks (31.3 +/- 5.4 N). Data were analyzed with 1-way ANOVA and Tukey HSD post-hoc tests at alpha = .05. Ribbed split crimpable hooks provided significantly less resistance to torsional displacement than the other types of hooks (P <001). There was no difference between coated split crimpable hooks and soldered brass surgical hooks (P >05). Under the conditions of this study, the results suggest that soldered brass surgical hooks and coated split crimpable hook attachments provide more stability to torsional dislodgement from a rectangular stabilizing archwire than ribbed split crimpable hooks.

  8. 49 CFR 40.153 - How does the MRO notify employees of their right to a test of the split specimen?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false How does the MRO notify employees of their right to a test of the split specimen? 40.153 Section 40.153 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Medical Review Officers and the Verification Process § 40.153 Ho...

  9. The biomechanical ambiguity of the articular surface.

    PubMed Central

    Kamalanathan, S; Broom, N D

    1993-01-01

    A series of micromechanical tests carried out on the articular surface of cartilage have provided an accurate description of the mechanical properties of any one site with respect to the orientation framework obtained from its characteristic split-line direction. Ultrastructural studies revealed little evidence that the split-line direction correlated strongly with any preferred alignment of fibrils. This paper therefore offers a new interpretation of the biomechanical significance of the widely used split-line test for the articular surface of cartilage. Images Fig. 9 Fig. 2 Fig. 6 Fig. 7 Fig. 8 Fig. 10 Fig. 11 PMID:8300433

  10. On the impact bending test technique for high-strength pipe steels

    NASA Astrophysics Data System (ADS)

    Arsenkin, A. M.; Odesskii, P. D.; Shabalov, I. P.; Likhachev, M. V.

    2015-10-01

    It is shown that the impact toughness (KCV-40 = 250 J/cm2) accepted for pipe steels of strength class K65 (σy ≥ 550 MPa) intended for large-diameter gas line pipes is ineffective to classify steels in fracture strength. The results obtained upon testing of specimens with a fatigue crack and additional sharp lateral grooves seem to be more effective. In energy consumption, a macrorelief with splits is found to be intermediate between ductile fracture and crystalline brittle fracture. A split formation mechanism is considered and a scheme is proposed for split formation.

  11. Asymmetric band gaps in a Rashba film system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carbone, C.; Moras, P.; Sheverdyaeva, P. M.

    The joint effect of exchange and Rashba spin-orbit interactions is examined on the surface and quantum well states of Ag 2 Bi -terminated Ag films grown on ferromagnetic Fe(110). The system displays a particular combination of time-reversal and translational symmetry breaking that strongly influences its electronic structure. Angle-resolved photoemission reveals asymmetric band-gap openings, due to spin-selective hybridization between Rashba-split surface states and exchange-split quantum well states. This results in an unequal number of states along positive and negative reciprocal space directions. We suggest that the peculiar asymmetry of the discovered electronic structure can have significant influence on spin-polarized transport properties.

  12. 76 FR 50204 - Decision and Order Granting a Waiver to Fujitsu General Limited From the Department of Energy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... Refrigerant Flow (VRF) multi-split commercial heat pump models specified in Fujitsu's petition for waiver. As... to test and rate these AIRSTAGE V-II VRF multi-split commercial heat pumps. DATES: This Decision and...) Standard 1230-2010, ``Performance Rating of VRF Multi-Split Air-Conditioning and Heat Pump Equipment'' to...

  13. Speech Adaptation to a Self-Inflicted Cosmetic Tongue Split: Perceptual and Ultrasonographic Analysis

    ERIC Educational Resources Information Center

    Bressmann, Tim

    2006-01-01

    In the cosmetic tongue split operation, the anterior tongue blade is split along the midline of the tongue. The goal of this case study was to obtain preliminary data on speech and tongue motility in a participant who had performed this operation on himself. The participant underwent an articulation test and a tongue motility assessment, as well…

  14. 49 CFR Appendix D to Part 40 - Report Format: Split Specimen Failure To Reconfirm

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Report Format: Split Specimen Failure To Reconfirm D Appendix D to Part 40 Transportation Office of the Secretary of Transportation PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Pt. 40, App. D Appendix D to Part 40—Report Format: Split Specimen Failure To Reconfirm Mail,...

  15. Mechanical and photoelastic analysis of conventional screws and cannulated screws for sagittal split osteotomy fixation: a comparative study.

    PubMed

    Lima, Cristina Jardelino de; Falci, Saulo Gabriel Moreira; Rodrigues, Danillo Costa; Marchiori, Érica Cristina; Moreira, Roger Willian Fernandes

    2015-12-01

    The aim of the present study was to use mechanical and photoelastic tests to compare the performance of cannulated screws with solid-core screws in sagittal split osteotomy fixation. Ten polyurethane mandibles, with a prefabricated sagittal split ramus osteotomy, were fixed with an L inverted technique and allocated to each group as follows: cannulated screw group (CSG), fixed with three 2.3-cannulated screws; and solid-core screw group (SCSG), fixed with three 2.3-solid-core screws. Vertical linear loading tests were performed. The differences between mean values were analyzed through T test for independent samples. The photoelastic test was carried out using a polariscope. The results revealed differences between the two groups only at 1 mm of displacement, in which the cannulated-screw revealed more resistance. Photoelastic test showed higher stress concentration close to mandibular branch in the solid-core group. Cannulated screws performed better than solid-core ones in a mechanical test at 1-mm displacement and photoelastic tests.

  16. The Development of a New Method of Idiographic Measurement for Dynamic Assessment Intervention

    ERIC Educational Resources Information Center

    Hurley, Emma; Murphy, Raegan

    2015-01-01

    This paper proposes a new method of idiographic measurement for dynamic assessment (DA) intervention. There are two main methods of measurement for DA intervention; split-half tests and integrated scoring systems. Split-half tests of ability have proved useful from a research perspective. Integrated scoring systems coupled with case studies are…

  17. Evaluation of Euler fluxes by a high-order CFD scheme: shock instability

    NASA Astrophysics Data System (ADS)

    Tu, Guohua; Zhao, Xiaohui; Mao, Meiliang; Chen, Jianqiang; Deng, Xiaogang; Liu, Huayong

    2014-05-01

    The construction of Euler fluxes is an important step in shock-capturing/upwind schemes. It is well known that unsuitable fluxes are responsible for many shock anomalies, such as the carbuncle phenomenon. Three kinds of flux vector splittings (FVSs) as well as three kinds of flux difference splittings (FDSs) are evaluated for the shock instability by a fifth-order weighted compact nonlinear scheme. The three FVSs are Steger-Warming splitting, van Leer splitting and kinetic flux vector splitting (KFVS). The three FDSs are Roe's splitting, advection upstream splitting method (AUSM) type splitting and Harten-Lax-van Leer (HLL) type splitting. Numerical results indicate that FVSs and high dissipative FDSs undergo a relative lower risk on the shock instability than that of low dissipative FDSs. However, none of the fluxes evaluated in the present study can entirely avoid the shock instability. Generally, the shock instability may be caused by any of the following factors: low dissipation, high Mach number, unsuitable grid distribution, large grid aspect ratio, and the relative shock-internal flow state (or position) between upstream and downstream shock waves. It comes out that the most important factor is the relative shock-internal state. If the shock-internal state is closer to the downstream state, the computation is at higher susceptibility to the shock instability. Wall-normal grid distribution has a greater influence on the shock instability than wall-azimuthal grid distribution because wall-normal grids directly impact on the shock-internal position. High shock intensity poses a high risk on the shock instability, but its influence is not as much as the shock-internal state. Large grid aspect ratio is also a source of the shock instability. Some results of a second-order scheme and a first-order scheme are also given. The comparison between the high-order scheme and the two low-order schemes indicates that high-order schemes are at a higher risk of the shock instability. Adding an entropy fix is very helpful in suppressing the shock instability for the two low-order schemes. When the high-order scheme is used, the entropy fix still works well for Roe's flux, but its effect on the Steger-Warming flux is trivial and not much clear.

  18. Influence of core design, production technique, and material selection on fracture behavior of yttria-stabilized tetragonal zirconia polycrystal fixed dental prostheses produced using different multilayer techniques: split-file, over-pressing, and manually built-up veneers.

    PubMed

    Mahmood, Deyar Jallal Hadi; Linderoth, Ewa H; Wennerberg, Ann; Vult Von Steyern, Per

    2016-01-01

    To investigate and compare the fracture strength and fracture mode in eleven groups of currently, the most commonly used multilayer three-unit all-ceramic yttria-stabilized tetragonal zirconia polycrystal (Y-TZP) fixed dental prostheses (FDPs) with respect to the choice of core material, veneering material area, manufacturing technique, design of connectors, and radii of curvature of FDP cores. A total of 110 three-unit Y-TZP FDP cores with one intermediate pontic were made. The FDP cores in groups 1-7 were made with a split-file design, veneered with manually built-up porcelain, computer-aided design-on veneers, and over-pressed veneers. Groups 8-11 consisted of FDPs with a state-of-the-art design, veneered with manually built-up porcelain. All the FDP cores were subjected to simulated aging and finally loaded to fracture. There was a significant difference (P<0.05) between the core designs, but not between the different types of Y-TZP materials. The split-file designs with VITABLOCS(®) (1,806±165 N) and e.max(®) ZirPress (1,854±115 N) and the state-of-the-art design with VITA VM(®) 9 (1,849±150 N) demonstrated the highest mean fracture values. The shape of a split-file designed all-ceramic reconstruction calls for a different dimension protocol, compared to traditionally shaped ones, as the split-file design leads to sharp approximal indentations acting as fractural impressions, thus decreasing the overall strength. The design of a framework is a crucial factor for the load bearing capacity of an all-ceramic FDP. The state-of-the-art design is preferable since the split-file designed cores call for a cross-sectional connector area at least 42% larger, to have the same load bearing capacity as the state-of-the-art designed cores. All veneering materials and techniques tested in the study, split-file, over-press, built-up porcelains, and glass-ceramics are, with a great safety margin, sufficient for clinical use both anteriorly and posteriorly. Analysis of the fracture pattern shows differences between the milled veneers and over-pressed or built-up veneers, where the milled ones show numerically more veneer cracks and the other groups only show complete connector fractures.

  19. Exposing the QCD Splitting Function with CMS Open Data.

    PubMed

    Larkoski, Andrew; Marzani, Simone; Thaler, Jesse; Tripathee, Aashish; Xue, Wei

    2017-09-29

    The splitting function is a universal property of quantum chromodynamics (QCD) which describes how energy is shared between partons. Despite its ubiquitous appearance in many QCD calculations, the splitting function cannot be measured directly, since it always appears multiplied by a collinear singularity factor. Recently, however, a new jet substructure observable was introduced which asymptotes to the splitting function for sufficiently high jet energies. This provides a way to expose the splitting function through jet substructure measurements at the Large Hadron Collider. In this Letter, we use public data released by the CMS experiment to study the two-prong substructure of jets and test the 1→2 splitting function of QCD. To our knowledge, this is the first ever physics analysis based on the CMS Open Data.

  20. [Divisibility of warfarin and fluindione tablets tested in elderly patients and their family circle].

    PubMed

    Pautas, Eric; Despres, Jérémie; Peyron, Isabelle; Golmard, Jean-Louis; Grange, Jennifer; Koenig, Nelly; Gouronnec, Adeline; Mitha, Nathalie; Siguret, Virginie; Gouin-Thibault, Isabelle

    2011-06-01

    Vitamin K antagonist tablets are often split to fractionate the dose by elderly patients. We performed a study in order to assess the divisibility of one dosage strength of score-lined warfarin and of score-lined fluindione. Due to a recent change in the pharmaceutical form of fluindione in order to improve the divisibility, the study was performed over 2 different periods (with the « old » and with the « new » pharmaceutical form). In each period, 10 patients mean aged 82 years, 10 relatives, 10 nurses, 10 medical doctors) were asked to split in half warfarin tablets (W2 1(st) period et W2 2(d) period) and fluindione tablets (F2 et F'2), and to split fluindione tablets into 4 fragments (F4 et F'4). The first end-point was the accuracy of splitting estimated by the difference between the real and the expected weight of fragmented tablets. The statistical analysis was performed using an ANOVA test with 2 variables, subject and drug. The difference between the 2 periods were analyzed using an ANOVA test with 2 variables, subject and period. Over the 2 periods, the differences between real and expected weight were of 4.65% for W2 1(st) phase, 9.48% for F2, 15.35% for F4, 5.56% for W2 2(d )period, 4.30% for F'2, and 6.98% for F'4. The quality of splitting was statistically poorer in the elderly patient group compared to other subjects. This study was not design to assess the clinical relevance (bleeding or thromboembolism) or the anticoagulation control of the variations in drug mass due to inappropriate splitting of tablets. However, split form of drugs should be prescribe with caution to elderly patients.

  1. WWSSF - a worldwide study on radioisotopic renal split function: reproducibility of renal split function assessment in children.

    PubMed

    Geist, Barbara Katharina; Dobrozemsky, Georg; Samal, Martin; Schaffarich, Michael P; Sinzinger, Helmut; Staudenherz, Anton

    2015-12-01

    The split or differential renal function is the most widely accepted quantitative parameter derived from radionuclide renography. To examine the intercenter variance of this parameter, we designed a worldwide round robin test. Five selected dynamic renal studies have been distributed all over the world by e-mail. Three of these studies are anonymized patient data acquired using the EANM standardized protocol and two studies are phantom studies. In a simple form, individual participants were asked to measure renal split function as well as to provide additional information such as data analysis software, positioning of background region of interest, or the method of calculation. We received the evaluation forms from 34 centers located in 21 countries. The analysis of the round robin test yielded an overall z-score of 0.3 (a z-score below 1 reflecting a good result). However, the z-scores from several centers were unacceptably high, with values greater than 3. In particular, the studies with impaired renal function showed a wide variance. A wide variance in the split renal function was found in patients with impaired kidney function. This study indicates the ultimate importance of quality control and standardization of the measurement of the split renal function. It is especially important with respect to the commonly accepted threshold for significant change in split renal function by 10%.

  2. Finding the right match: Mindfulness training may potentiate the therapeutic effect of non-judgment of inner experience on smoking cessation

    PubMed Central

    Schuman-Olivier, Zev D.; Hoeppner, Bettina B.; Evins, A. Eden; Brewer, Judson

    2014-01-01

    Mindfulness Training (MT) is an emerging therapeutic modality for addictive disorders. Non-judgment of inner experience, a component of mindfulness, may influence addiction treatment response. To test whether this component influences smoking cessation, tobacco smokers (n=85) in a randomized control trial of MT vs. Freedom from Smoking (FFS), a standard cognitive-behaviorally-oriented treatment, were divided into split-half subgroups based on baseline Five Facet Mindfulness Questionnaire non-judgment subscale. Smokers who rarely judge inner experience (non-judgment > 30.5) smoked less during follow-up when randomized to MT (3.9 cigs/d) vs. FFS (11.1 cigs/d), p <0.01. Measuring trait non-judgment may help personalize treatment assignments, improving outcomes. PMID:24611853

  3. INFLUENCE OF TABLET SPLITTING ON CONTENT UNIFORMITY OF LISINOPRIL/ HYDROCHLORTHIAZIDE TABLETS

    PubMed Central

    Vranić, Edina; Uzunović, Alija

    2007-01-01

    Dose-related adverse effects of medications are a major problem in modern medical practice. The “correct” dose, based on drug company guidelines in package inserts, may not be correct for many patients. Tablet splitting or dividing has been an accepted practice for many years as a means of obtaining the prescribed dose of medication. As model tablets for this investigation, two batches of lisinopril-hydrochlorothiazide scored tablets labeled to contain 20/12,5 mg were used. The aim of this study was to establish possible influence of tablet splitting on content uniformity of lisinopril/hydrochlorthiazide tablets. Determination of the content uniformity of lisinopril and hydrochlorthiazide in our batches, was carried out by HPLC method. The results of content uniformity studies for halves of tablets containing combination of lisinopril-hydrochlorthiazide (supposed to contain 50% of stated 20/12,5 mg in the whole tablet) were: 49,60 ±3,29% and 49,29±0,60 % (lisinopril); 50,33±3,50% and 50,69±1,95% (hydrochlorthiazide) for batch I and II, respectively. We can conclude that the results obtained in this study support an option of tablet splitting, which is very important for obtaining the required dosage when a dosage form of the required strength is unavailable, and for better individualization of the therapy PMID:18039191

  4. Influence of F- on stark splitting of Yb3+ and the thermal expansion of silica glass

    NASA Astrophysics Data System (ADS)

    Cao, Yabin; Chen, Si; Shao, Chongyun; Yu, Chunlei

    2018-06-01

    A local phosphate/fluoride environment of Yb3+ was created in silica glass using a multi-step method. The influence of F- on the Stark splitting of Yb3+ in Al3+/P5+/F- co-doped silica glass was studied at room-temperature, in addition to its effect on the thermal expansion performance of the glass matrix. The results indicate that Yb3+ ions in Al3+/P5+/F- co-doped silica glass have a larger Stark splitting energy of 2F7/2 compared to Al3+/P5+ co-doped silica glass. Moreover, a larger integrated absorption cross-section (34.58 pm2 × nm), stimulated emission cross-section (0.63 pm2), and better thermal expansion performance (1.3062 × 10-6 K- at 100 °C) are achieved in Al3+/P5+/F- co-doped silica glass. Finally, different function mechanisms of F- in silica and phosphate glasses were analyzed and the F-Si bond was used to explain the results in silica glass. The combination of low refractive index, large Stark splitting energy of 2F7/2, and small thermal expansion makes Al3+/P5+/F- co-doped silica glass a preferred material for large mode area fibers for high-power laser applications.

  5. Modeling vehicle operating speed on urban roads in Montreal: a panel mixed ordered probit fractional split model.

    PubMed

    Eluru, Naveen; Chakour, Vincent; Chamberlain, Morgan; Miranda-Moreno, Luis F

    2013-10-01

    Vehicle operating speed measured on roadways is a critical component for a host of analysis in the transportation field including transportation safety, traffic flow modeling, roadway geometric design, vehicle emissions modeling, and road user route decisions. The current research effort contributes to the literature on examining vehicle speed on urban roads methodologically and substantively. In terms of methodology, we formulate a new econometric model framework for examining speed profiles. The proposed model is an ordered response formulation of a fractional split model. The ordered nature of the speed variable allows us to propose an ordered variant of the fractional split model in the literature. The proposed formulation allows us to model the proportion of vehicles traveling in each speed interval for the entire segment of roadway. We extend the model to allow the influence of exogenous variables to vary across the population. Further, we develop a panel mixed version of the fractional split model to account for the influence of site-specific unobserved effects. The paper contributes substantively by estimating the proposed model using a unique dataset from Montreal consisting of weekly speed data (collected in hourly intervals) for about 50 local roads and 70 arterial roads. We estimate separate models for local roads and arterial roads. The model estimation exercise considers a whole host of variables including geometric design attributes, roadway attributes, traffic characteristics and environmental factors. The model results highlight the role of various street characteristics including number of lanes, presence of parking, presence of sidewalks, vertical grade, and bicycle route on vehicle speed proportions. The results also highlight the presence of site-specific unobserved effects influencing the speed distribution. The parameters from the modeling exercise are validated using a hold-out sample not considered for model estimation. The results indicate that the proposed panel mixed ordered probit fractional split model offers promise for modeling such proportional ordinal variables. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Sleep inertia during a simulated 6-h on/6-h off fixed split duty schedule.

    PubMed

    Hilditch, Cassie J; Short, Michelle; Van Dongen, Hans P A; Centofanti, Stephanie A; Dorrian, Jillian; Kohler, Mark; Banks, Siobhan

    Sleep inertia is a safety concern for shift workers returning to work soon after waking up. Split duty schedules offer an alternative to longer shift periods, but introduce additional wake-ups and may therefore increase risk of sleep inertia. This study investigated sleep inertia across a split duty schedule. Sixteen participants (age range 21-36 years; 10 females) participated in a 9-day laboratory study with two baseline nights (10 h time in bed, [TIB]), four 24-h periods of a 6-h on/6-h off split duty schedule (5-h TIB in off period; 10-h TIB per 24 h) and two recovery nights. Two complementary rosters were evaluated, with the timing of sleep and wake alternating between the two rosters (2 am/2 pm wake-up roster versus 8 am/8 pm wake-up roster). At 2, 17, 32 and 47 min after scheduled awakening, participants completed an 8-min inertia test bout, which included a 3-min psychomotor vigilance test (PVT-B), a 3-min Digit-Symbol Substitution Task (DSST), the Karolinska Sleepiness Scale (KSS), and the Samn-Perelli Fatigue Scale (SP-Fatigue). Further testing occurred every 2 h during scheduled wakefulness. Performance was consistently degraded and subjective sleepiness/fatigue was consistently increased during the inertia testing period as compared to other testing times. Morning wake-ups (2 am and 8 am) were associated with higher levels of sleep inertia than later wake-ups (2 pm and 8 pm). These results suggest that split duty workers should recognise the potential for sleep inertia after waking, especially during the morning hours.

  7. Electromigration-induced plastic deformation in passivated metal lines

    NASA Astrophysics Data System (ADS)

    Valek, B. C.; Bravman, J. C.; Tamura, N.; MacDowell, A. A.; Celestre, R. S.; Padmore, H. A.; Spolenak, R.; Brown, W. L.; Batterman, B. W.; Patel, J. R.

    2002-11-01

    We have used scanning white beam x-ray microdiffraction to study microstructural evolution during an in situ electromigration experiment on a passivated Al(Cu) test line. The data show plastic deformation and grain rotations occurring under the influence of electromigration, seen as broadening, movement, and splitting of reflections diffracted from individual metal grains. We believe this deformation is due to localized shear stresses that arise due to the inhomogeneous transfer of metal along the line. Deviatoric stress measurements show changes in the components of stress within the line, including relaxation of stress when current is removed.

  8. Optimal preparation-to-colonoscopy interval in split-dose PEG bowel preparation determines satisfactory bowel preparation quality: an observational prospective study.

    PubMed

    Seo, Eun Hee; Kim, Tae Oh; Park, Min Jae; Joo, Hee Rin; Heo, Nae Yun; Park, Jongha; Park, Seung Ha; Yang, Sung Yeon; Moon, Young Soo

    2012-03-01

    Several factors influence bowel preparation quality. Recent studies have indicated that the time interval between bowel preparation and the start of colonoscopy is also important in determining bowel preparation quality. To evaluate the influence of the preparation-to-colonoscopy (PC) interval (the interval of time between the last polyethylene glycol dose ingestion and the start of the colonoscopy) on bowel preparation quality in the split-dose method for colonoscopy. Prospective observational study. University medical center. A total of 366 consecutive outpatients undergoing colonoscopy. Split-dose bowel preparation and colonoscopy. The quality of bowel preparation was assessed by using the Ottawa Bowel Preparation Scale according to the PC interval, and other factors that might influence bowel preparation quality were analyzed. Colonoscopies with a PC interval of 3 to 5 hours had the best bowel preparation quality score in the whole, right, mid, and rectosigmoid colon according to the Ottawa Bowel Preparation Scale. In multivariate analysis, the PC interval (odds ratio [OR] 1.85; 95% CI, 1.18-2.86), the amount of PEG ingested (OR 4.34; 95% CI, 1.08-16.66), and compliance with diet instructions (OR 2.22l 95% CI, 1.33-3.70) were significant contributors to satisfactory bowel preparation. Nonrandomized controlled, single-center trial. The optimal time interval between the last dose of the agent and the start of colonoscopy is one of the important factors to determine satisfactory bowel preparation quality in split-dose polyethylene glycol bowel preparation. Copyright © 2012 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.

  9. Avoiding Split Attention in Computer-Based Testing: Is Neglecting Additional Information Facilitative?

    ERIC Educational Resources Information Center

    Jarodzka, Halszka; Janssen, Noortje; Kirschner, Paul A.; Erkens, Gijsbert

    2015-01-01

    This study investigated whether design guidelines for computer-based learning can be applied to computer-based testing (CBT). Twenty-two students completed a CBT exam with half of the questions presented in a split-screen format that was analogous to the original paper-and-pencil version and half in an integrated format. Results show that students…

  10. Accuracy of tablet splitting and liquid measurements: an examination of who, what and how.

    PubMed

    Abu-Geras, Dana; Hadziomerovic, Dunja; Leau, Andrew; Khan, Ramzan Nazim; Gudka, Sajni; Locher, Cornelia; Razaghikashani, Maryam; Lim, Lee Yong

    2017-05-01

    To examine factors that might affect the ability of patients to accurately halve tablets or measure a 5-ml liquid dose. Eighty-eight participants split four different placebo tablets by hand and using a tablet splitter, while 85 participants measured 5 ml of water, 0.5% methylcellulose (MC) and 1% MC using a syringe and dosing cup. Accuracy of manipulation was determined by mass measurements. The general population was less able than pharmacy students to break tablets into equal parts, although age, gender and prior experience were insignificant factors. Greater accuracy of tablet halving was observed with tablet splitter, with scored tablets split more equally than unscored tablets. Tablet size did not affect the accuracy of splitting. However, >25% of small scored tablets failed to be split by hand, and 41% of large unscored tablets were split into >2 portions in the tablet splitter. In liquid measurement, the syringe provided more accurate volume measurements than the dosing cup, with higher accuracy observed for the more viscous MC solutions than water. Formulation characteristics and manipulation technique have greater influences on the accuracy of medication modification and should be considered in off-label drug use in vulnerable populations. © 2016 Royal Pharmaceutical Society.

  11. Phenomenological study of a cellular material behaviour under dynamic loadings

    NASA Astrophysics Data System (ADS)

    Bouix, R.; Viot, Ph.; Lataillade, J.-L.

    2006-08-01

    Polypropylene foams are cellular materials, which are often use to fill structures subjected to crash or violent impacts. Therefore, it is necessary to know and to characterise in experiments their mechanical behaviour in compression at high strain rates. So, several apparatus have been used in order to highlight the influence of strain rate, material density and also temperature. A split Hopkinson Pressure Bar has been used for impact tests, a fly wheel to test theses materials at medium strain rate and an electro-mechanical testing machine associated to a climatic chamber for temperature tests. Then, a rheological model has been used in order to describe the material behaviour. The mechanical response to compression of these foams presents three typical domains: a linear elastic step, a wide collapse plateau stress, which leads to a densification, which are related to a standard rheological model.

  12. Correlation of Visuospatial Ability and EEG Slowing in Patients with Parkinson's Disease

    PubMed Central

    Meyer, Antonia; Chaturvedi, Menorca; Hatz, Florian; Gschwandtner, Ute

    2017-01-01

    Background. Visuospatial dysfunction is among the first cognitive symptoms in Parkinson's disease (PD) and is often predictive for PD-dementia. Furthermore, cognitive status in PD-patients correlates with quantitative EEG. This cross-sectional study aimed to investigate the correlation between EEG slowing and visuospatial ability in nondemented PD-patients. Methods. Fifty-seven nondemented PD-patients (17 females/40 males) were evaluated with a comprehensive neuropsychological test battery and a high-resolution 256-channel EEG was recorded. A median split was performed for each cognitive test dividing the patients sample into either a normal or lower performance group. The electrodes were split into five areas: frontal, central, temporal, parietal, and occipital. A linear mixed effects model (LME) was used for correlational analyses and to control for confounding factors. Results. Subsequently, for the lower performance, LME analysis showed a significant positive correlation between ROCF score and parietal alpha/theta ratio (b = .59, p = .012) and occipital alpha/theta ratio (b = 0.50, p = .030). No correlations were found in the group of patients with normal visuospatial abilities. Conclusion. We conclude that a reduction of the parietal alpha/theta ratio is related to visuospatial impairments in PD-patients. These findings indicate that visuospatial impairment in PD-patients could be influenced by parietal dysfunction. PMID:28348918

  13. Development of new flux splitting schemes. [computational fluid dynamics algorithms

    NASA Technical Reports Server (NTRS)

    Liou, Meng-Sing; Steffen, Christopher J., Jr.

    1992-01-01

    Maximizing both accuracy and efficiency has been the primary objective in designing a numerical algorithm for computational fluid dynamics (CFD). This is especially important for solutions of complex three dimensional systems of Navier-Stokes equations which often include turbulence modeling and chemistry effects. Recently, upwind schemes have been well received for their capability in resolving discontinuities. With this in mind, presented are two new flux splitting techniques for upwind differencing. The first method is based on High-Order Polynomial Expansions (HOPE) of the mass flux vector. The second new flux splitting is based on the Advection Upwind Splitting Method (AUSM). The calculation of the hypersonic conical flow demonstrates the accuracy of the splitting in resolving the flow in the presence of strong gradients. A second series of tests involving the two dimensional inviscid flow over a NACA 0012 airfoil demonstrates the ability of the AUSM to resolve the shock discontinuity at transonic speed. A third case calculates a series of supersonic flows over a circular cylinder. Finally, the fourth case deals with tests of a two dimensional shock wave/boundary layer interaction.

  14. Effect of Lactobacillus helveticus and Propionibacterium freudenrichii ssp. shermanii combinations on propensity for split defect in Swiss cheese.

    PubMed

    White, S R; Broadbent, J R; Oberg, C J; McMahon, D J

    2003-03-01

    One of the least controlled defects in Swiss cheese is development of splits that appear during refrigerated storage after cheese is removed from the warm room. Such fissures, or cracks, in the body of the cheese can be as short as 1 cm, or long enough to span a 90-kg block. A 2 x 2 x 2 factorial experiment was used to determine the effect of different Lactobacillus helveticus/Propionibacterium freudenreichii ssp. shermanii starter culture combinations on the occurrence of split defect in Swiss cheese. Eights vats of cheese were made in summer and eight in winter. Each 90-kg block of cheese was cut into twenty-four 4-kg blocks and graded based on the presence of splits. Only small variations were found in the composition of cheeses made during the same season. There were no correlations between moisture, pH, fat, protein, calcium, lactose contents, D/L lactate ratio, or protein degradation that could be used to predict splits after 90 d of storage. However, cheese made in the summer had 2% higher moisture content and a greater prevalence of splits. There was a sixfold increase in amount of downgraded cheese between the best and worst culture combinations used during cheese manufacture. After 90-d storage, 14 to 90% of cheese had splits in the summer, and 1 to 6% in the winter. Split formation increased with time from 60 to 120 d of storage and extent of split formation was influenced by both the lactobacilli and propionibacteria cultures used.

  15. Split-Ring Springback Simulations with the Non-associated Flow Rule and Evolutionary Elastic-Plasticity Models

    NASA Astrophysics Data System (ADS)

    Lee, K. J.; Choi, Y.; Choi, H. J.; Lee, J. Y.; Lee, M. G.

    2018-03-01

    Finite element simulations and experiments for the split-ring test were conducted to investigate the effect of anisotropic constitutive models on the predictive capability of sheet springback. As an alternative to the commonly employed associated flow rule, a non-associated flow rule for Hill1948 yield function was implemented in the simulations. Moreover, the evolution of anisotropy with plastic deformation was efficiently modeled by identifying equivalent plastic strain-dependent anisotropic coefficients. Comparative study with different yield surfaces and elasticity models showed that the split-ring springback could be best predicted when the anisotropy in both the R value and yield stress, their evolution and variable apparent elastic modulus were taken into account in the simulations. Detailed analyses based on deformation paths superimposed on the anisotropic yield functions predicted by different constitutive models were provided to understand the complex springback response in the split-ring test.

  16. Split-Ring Springback Simulations with the Non-associated Flow Rule and Evolutionary Elastic-Plasticity Models

    NASA Astrophysics Data System (ADS)

    Lee, K. J.; Choi, Y.; Choi, H. J.; Lee, J. Y.; Lee, M. G.

    2018-06-01

    Finite element simulations and experiments for the split-ring test were conducted to investigate the effect of anisotropic constitutive models on the predictive capability of sheet springback. As an alternative to the commonly employed associated flow rule, a non-associated flow rule for Hill1948 yield function was implemented in the simulations. Moreover, the evolution of anisotropy with plastic deformation was efficiently modeled by identifying equivalent plastic strain-dependent anisotropic coefficients. Comparative study with different yield surfaces and elasticity models showed that the split-ring springback could be best predicted when the anisotropy in both the R value and yield stress, their evolution and variable apparent elastic modulus were taken into account in the simulations. Detailed analyses based on deformation paths superimposed on the anisotropic yield functions predicted by different constitutive models were provided to understand the complex springback response in the split-ring test.

  17. A high order semi-Lagrangian discontinuous Galerkin method for Vlasov-Poisson simulations without operator splitting

    NASA Astrophysics Data System (ADS)

    Cai, Xiaofeng; Guo, Wei; Qiu, Jing-Mei

    2018-02-01

    In this paper, we develop a high order semi-Lagrangian (SL) discontinuous Galerkin (DG) method for nonlinear Vlasov-Poisson (VP) simulations without operator splitting. In particular, we combine two recently developed novel techniques: one is the high order non-splitting SLDG transport method (Cai et al. (2017) [4]), and the other is the high order characteristics tracing technique proposed in Qiu and Russo (2017) [29]. The proposed method with up to third order accuracy in both space and time is locally mass conservative, free of splitting error, positivity-preserving, stable and robust for large time stepping size. The SLDG VP solver is applied to classic benchmark test problems such as Landau damping and two-stream instabilities for VP simulations. Efficiency and effectiveness of the proposed scheme is extensively tested. Tremendous CPU savings are shown by comparisons between the proposed SL DG scheme and the classical Runge-Kutta DG method.

  18. Experimental Study of Split-Path Transmission Load Sharing

    NASA Technical Reports Server (NTRS)

    Krantz, Timothy L.; Delgado, Irebert R.

    1996-01-01

    Split-path transmissions are promising, attractive alternatives to the common planetary transmissions for helicopters. The split-path design offers two parallel paths for transmitting torque from the engine to the rotor. Ideally, the transmitted torque is shared equally between the two load paths; however, because of manufacturing tolerances, the design must be sized to allow for other than equal load sharing. To study the effect of tolerances, experiments were conducted using the NASA split-path test gearbox. Two gearboxes, nominally identical except for manufacturing tolerances, were tested. The clocking angle was considered to be a design parameter and used to adjust the load sharing of an otherwise fixed design. The torque carried in each path was measured for a matrix of input torques and clocking angles. The data were used to determine the optimal value and a tolerance for the clocking angles such that the most heavily loaded split path carried no greater than 53 percent of an input shaft torque of 367 N-m. The range of clocking angles satisfying this condition was -0.0012 +/- 0.0007 rad for box 1 and -0.0023 +/- 0.0009 rad for box 2. This study indicates that split-path gearboxes can be used successfully in rotorcraft and can be manufactured with existing technology.

  19. Shear Wave Splitting Inversion in a Complex Crust

    NASA Astrophysics Data System (ADS)

    Lucas, A.

    2015-12-01

    Shear wave splitting (SWS) inversion presents a method whereby the upper crust can be interrogated for fracture density. It is caused when a shear wave traverses an area of anisotropy, splits in two, with each wave experiencing a different velocity resulting in an observable separation in arrival times. A SWS observation consists of the first arrival polarization direction and the time delay. Given the large amount of data common in SWS studies, manual inspection for polarization and time delay is considered prohibitively time intensive. All automated techniques used can produce high amounts of observations falsely interpreted as SWS. Thus introducing error into the interpretation. The technique often used for removing these false observations is to manually inspect all SWS observations defined as high quality by the automated routine, and remove false identifications. We investigate the nature of events falsely identified compared to those correctly identified. Once this identification is complete we conduct a inversion for crack density from SWS time delay. The current body of work on linear SWS inversion utilizes an equation that defines the time delay between arriving shear waves with respect to fracture density. This equation makes the assumption that no fluid flow occurs as a result of the passing shear wave, a situation called squirt flow. We show that the assumption is not applicable in all geological situations. When it is not true, its use in an inversion produces a result which is negatively affected by the assumptions. This is shown to be the case at the test case of 6894 SWS observations gathered in a small area at Puna geothermal field, Hawaii. To rectify this situation, a series of new time delay formulae, applicable to linear inversion, are derived from velocity equations presented in literature. The new formula use a 'fluid influence parameter' which indicates the degree to which squirt flow is influencing the SWS. It is found that accounting for squirt flow better fits the data and is more applicable. The fluid influence factor that best describes the data can be identified prior to solving the inversion. Implementing this formula in a linear inversion has a significantly improved fit to the time delay observations than that of the current methods.

  20. Predicting SKS-splitting from 35 Myr of subduction and mantle flow evolution in the western Mediterranean

    NASA Astrophysics Data System (ADS)

    Chertova, Maria; Spakman, Wim; Faccenda, Manuele

    2017-04-01

    We investigate the development of mantle anisotropy associated with the evolution of the Rif-Gibraltar-Betic (RGB) slab of the western Mediterranean and predict SKS-splitting directions for comparison with the recent observations compiled in Diaz and Gallart (2014). Our numerical model of slab evolution starts at 35 Ma and builds on our on recent work (Chertova et al., 2014) with the extension of imposing mantle flow velocities on the side boundaries of the model (Chertova et al., 2017). For the calculation of the evolution of finite strain deformation from the mantle flow field and for prediction of SKS-splitting directions we use the modified D-Rex program of Faccenda (2014). We test the predicted splitting observations against present-day shear wave splitting observations for subduction models with open boundary conditions (Chertova, 2014) and for models with various prescribed mantle flow conditions on the model side boundaries. The latter are predicted time-dependent (1 Myr time steps) velocity boundary conditions computed from back-advection of a temperature and density model of the present-day mantle scaled from a global seismic tomography model (Steinberger et al., 2015). These boundary conditions where used recently to demonstrate the relative insensitivity of RGB slab position and overall slab morphology for external mantle flow (Chertova et al., 2017). Using open boundaries only we obtain a poor to moderate fit between predicted and observed splitting directions after 35 Myr of slab and mantle flow evolution. In contrast, a good fit is obtained when imposing the computed mantle flow velocities on the western, southern, and northern boundaries during 35 Myr of model evolution. This successful model combines local slab-driven mantle flow with remotely forced mantle flow. We are in the process to repeat these calculations for shorter periods of mantle flow evolution to determine how much of past mantle flow is implicitly recorded in present-day observation of SKS splitting. In combination with our recent work on the influence of external mantle flow on RGB slab evolution (Chertova et al., 2017) we have also demonstrated that (1) the preferred slab evolution model of Chertova et al. (2014; their "Scenario 1" in which RGB subduction starts at the Baleares margin some 35 Myr ago and then rolls back southward to Africa and next to the W and finally to NW to create the future Rif-Gibraltar-Betics cordillera), is robust with respect to the impact of global mantle flow for the past 35 Myr and that (2) only the combination of global flow with local slab-induced flow leads to mantle anisotropy prediction that consistent with present-day observations of present-day SKS splitting. Steinberger, B., W.Spakman, P.Japsen and T.H.Torsvik (2015), The key role of global solid Earth processes in the late Cenozoic intensification of Greenland glaciation. Terra Nova, 27 Chertova, M.V., W.Spakman, T. Geenen, A.P. van den Berg, D.J.J. van Hinsbergen (2014), Underpinning tectonic reconstructions of the western Mediterranean region with dynamic slab evolution from 3-D numerical modeling. J. Geophys. Res. Solid Earth Chertova, M., W.Spakman and B.Steinberger (2017), Mantle flow influence on subduction evolution, submitted to J. Geophys. Res. Solid Earth Faccenda, M. (2014), Mid mantle seismic anisotropy around subduction zones, Physics of the Earth and Planetary Interiors Diaz, J., and J. Gallart (2014) Seismic anisotropy from the Variscan core of Iberia to the western African Craton: New constraints on upper mantle flow at regional scale. Earth and Planetary Science Letters

  1. Voltage‐Controlled Switching of Strong Light–Matter Interactions using Liquid Crystals

    PubMed Central

    Hertzog, Manuel; Rudquist, Per; Hutchison, James A.; George, Jino; Ebbesen, Thomas W.

    2017-01-01

    Abstract We experimentally demonstrate a fine control over the coupling strength of vibrational light–matter hybrid states by controlling the orientation of a nematic liquid crystal. Through an external voltage, the liquid crystal is seamlessly switched between two orthogonal directions. Using these features, for the first time, we demonstrate electrical switching and increased Rabi splitting through transition dipole moment alignment. The C−Nstr vibration on the liquid crystal molecule is coupled to a cavity mode, and FT‐IR is used to probe the formed vibropolaritonic states. A switching ratio of the Rabi splitting of 1.78 is demonstrated between the parallel and the perpendicular orientation. Furthermore, the orientational order increases the Rabi splitting by 41 % as compared to an isotropic liquid. Finally, by examining the influence of molecular alignment on the Rabi splitting, the scalar product used in theoretical modeling between light and matter in the strong coupling regime is verified. PMID:29155469

  2. Towards Versatile and Sustainable Hydrogen Production through Electrocatalytic Water Splitting: Electrolyte Engineering

    PubMed Central

    Shinagawa, Tatsuya

    2017-01-01

    Abstract Recent advances in power generation from renewable resources necessitate conversion of electricity to chemicals and fuels in an efficient manner. Electrocatalytic water splitting is one of the most powerful and widespread technologies. The development of highly efficient, inexpensive, flexible, and versatile water electrolysis devices is desired. This review discusses the significance and impact of the electrolyte on electrocatalytic performance. Depending on the circumstances under which the water splitting reaction is conducted, the required solution conditions, such as the identity and molarity of ions, may significantly differ. Quantitative understanding of such electrolyte properties on electrolysis performance is effective to facilitate the development of efficient electrocatalytic systems. The electrolyte can directly participate in reaction schemes (kinetics), affect electrode stability, and/or indirectly impact the performance by influencing the concentration overpotential (mass transport). This review aims to guide fine‐tuning of the electrolyte properties, or electrolyte engineering, for (photo)electrochemical water splitting reactions. PMID:27984671

  3. Revealing Nanostructures through Plasmon Polarimetry.

    PubMed

    Kleemann, Marie-Elena; Mertens, Jan; Zheng, Xuezhi; Cormier, Sean; Turek, Vladimir; Benz, Felix; Chikkaraddy, Rohit; Deacon, William; Lombardi, Anna; Moshchalkov, Victor V; Vandenbosch, Guy A E; Baumberg, Jeremy J

    2017-01-24

    Polarized optical dark-field spectroscopy is shown to be a versatile noninvasive probe of plasmonic structures that trap light to the nanoscale. Clear spectral polarization splittings are found to be directly related to the asymmetric morphology of nanocavities formed between faceted gold nanoparticles and an underlying gold substrate. Both experiment and simulation show the influence of geometry on the coupled system, with spectral shifts Δλ = 3 nm from single atoms. Analytical models allow us to identify the split resonances as transverse cavity modes, tightly confined to the nanogap. The direct correlation of resonance splitting with atomistic morphology allows mapping of subnanometre structures, which is crucial for progress in extreme nano-optics involving chemistry, nanophotonics, and quantum devices.

  4. Two-loop mass splittings in electroweak multiplets: Winos and minimal dark matter

    NASA Astrophysics Data System (ADS)

    McKay, James; Scott, Pat

    2018-03-01

    The radiatively-induced splitting of masses in electroweak multiplets is relevant for both collider phenomenology and dark matter. Precision two-loop corrections of O (MeV ) to the triplet mass splitting in the wino limit of the minimal supersymmetric standard model can affect particle lifetimes by up to 40%. We improve on previous two-loop self-energy calculations for the wino model by obtaining consistent input parameters to the calculation via two-loop renormalization-group running, and including the effect of finite light quark masses. We also present the first two-loop calculation of the mass splitting in an electroweak fermionic quintuplet, corresponding to the viable form of minimal dark matter (MDM). We place significant constraints on the lifetimes of the charged and doubly-charged fermions in this model. We find that the two-loop mass splittings in the MDM quintuplet are not constant in the large-mass limit, as might naively be expected from the triplet calculation. This is due to the influence of the additional heavy fermions in loop corrections to the gauge boson propagators.

  5. Analytical study of body waves in orthorhombic media and comparison with SKS-phase observations from selected stations

    NASA Astrophysics Data System (ADS)

    Löberich, Eric; Bokelmann, Götz

    2016-04-01

    Anisotropic effects of wave propagation, observed in the Earth, provide interesting applications in basic research and practice, e.g., in reservoir geophysics and other fields. Teleseismic waves often evidence upper mantle anisotropy, as created by aligned olivine grains. While each grain is associated with orthorhombic symmetry, the preferred alignment may lead to a transversely isotropic characteristic. Considering body waves passing through an anisotropic medium, a splitting of shear waves can usually be observed, since their transverse polarization leads to a separation of the two quasi-shear waves. The associated splitting-delay is generated if the related fast and slow seismic velocities differ. Most of the previous shear-wave splitting investigations were based on the common assumption of near-vertical incidence. However, the influence of increasing incidence angles, which may lead to angular dependent splitting-delay and fast polarization orientation, has been pointed out by Davis (2003). Our study investigates the occurrence of these postulated dependences on azimuth and incidence angle (distance), examining splitting observations in SKS-recordings at selected broadband stations (e.g., Djibouti and Red Lake, Ontario).

  6. Response of automated tow placed laminates to stress concentrations

    NASA Technical Reports Server (NTRS)

    Cairns, Douglas S.; Ilcewicz, Larry B.; Walker, Tom

    1993-01-01

    In this study, the response of laminates with stress concentrations is explored. Automated Tow Placed (ATP, also known as Fiber Placement) laminates are compared to conventional tape layup manufacturing. Previous tensile fracture tests on fiber placed laminates show an improvement in tensile fracture of large notches over 20 percent compared to tape layup laminates. A hierarchial modeling scheme is presented. In this scheme, a global model is developed for laminates with notches. A local model is developed to study the influence of inhomogeneities at the notch tip, which are a consequence of the fiber placement manufacturing technique. In addition, a stacked membrane model was developed to study delaminations and splitting on a ply-by-ply basis. The results indicate that some benefit with respect to tensile fracture (up to 11 percent) can be gained from inhomogeneity alone, but that the most improvement may be obtained with splitting and delaminations which are more severe in the case of fiber placement compared to tape layup. Improvements up to 36 percent were found from the model for fiber placed laminates with damage at the notch tip compared to conventional tape layup.

  7. Changes of strength characteristics of pervious concrete due to variations in water to cement ratio

    NASA Astrophysics Data System (ADS)

    Kovac, M.; Sicakova, A.

    2017-10-01

    Pervious concrete is considered to be a sustainable pavement material due to high water permeability. The experiment presented in this paper was aimed at study the influence of water to cement ratio on both the compressive and splitting tensile strength of pervious concrete. Typically, less water content in concrete mixture leads to less porosity of cement paste and thus it provides desirable mechanical properties. In case of conventional dense concrete, the lower is the water to cement ratio, the higher or better is the strength, density and durability of concrete. This behaviour is not quite clear in case of pervious concrete because of low amount of cement paste present. Results of compressive and splitting tensile strength of pervious concrete are discussed in the paper while taking into account values measured after 2 and 28 days of hardening and variations in water to cement ratio. The results showed that changes of water to cement ratio from 0.25 to 0.35 caused only slight differences in strength characteristics, and this applied to both types of tested strength.

  8. A novel pillar indentation splitting test for measuring fracture toughness of thin ceramic coatings

    DOE PAGES

    Sebastiani, Marco; Johanns, K. E.; Herbert, Erik G.; ...

    2014-05-16

    Fracture toughness is an important material property that plays a role in determining the in-service mechanical performance and adhesion of thin ceramic films. Unfortunately, measuring thin film fracture toughness is affected by influences from the substrate and the large residual stresses that can exist in the films. In this paper, we explore a promising new technique that potentially overcomes these problems based on nanoindentation testing of micro-pillars produced by focused ion beam milling of the films. By making the pillar diameter approximately equal to its length, the residual stress in the pillar’s upper portion is almost fully relaxed, and whenmore » indented with a sharp Berkovich indenter, the pillars fracture by splitting at reproducible loads that are readily quantified by a sudden displacement excursion in the load displacement behavior. Cohesive finite element simulations are used to analyze and develop, for a given material, a simple relation between the critical load at failure, pillar radius, and fracture toughness. The main novel aspect of this work is that neither crack geometries nor crack sizes need to be measured post test. Furthermore, the residual stress can be measured at the same time with toughness, by comparing the indentation results from the stress-free pillars and the as-deposited film. The method is tested on three different hard coatings formed by physical vapor deposition: titanium nitride, chromium nitride, and a CrAlN/Si 3N 4 nanocomposite. Results compare well to independently measured values of fracture toughness for the three brittle films. The technique offers several benefits over existing methods.« less

  9. Walk, Look, Remember: The Influence of the Gallery's Spatial Layout on Human Memory for an Art Exhibition.

    PubMed

    Krukar, Jakub

    2014-09-01

    The spatial organisation of museums and its influence on the visitor experience has been the subject of numerous studies. Previous research, despite reporting some actual behavioural correlates, rarely had the possibility to investigate the cognitive processes of the art viewers. In the museum context, where spatial layout is one of the most powerful curatorial tools available, attention and memory can be measured as a means of establishing whether or not the gallery fulfils its function as a space for contemplating art. In this exploratory experiment, 32 participants split into two groups explored an experimental, non-public exhibition and completed two unanticipated memory tests afterwards. The results show that some spatial characteristics of an exhibition can inhibit the recall of pictures and shift the focus to perceptual salience of the artworks.

  10. Walk, Look, Remember: The Influence of the Gallery’s Spatial Layout on Human Memory for an Art Exhibition

    PubMed Central

    Krukar, Jakub

    2014-01-01

    The spatial organisation of museums and its influence on the visitor experience has been the subject of numerous studies. Previous research, despite reporting some actual behavioural correlates, rarely had the possibility to investigate the cognitive processes of the art viewers. In the museum context, where spatial layout is one of the most powerful curatorial tools available, attention and memory can be measured as a means of establishing whether or not the gallery fulfils its function as a space for contemplating art. In this exploratory experiment, 32 participants split into two groups explored an experimental, non-public exhibition and completed two unanticipated memory tests afterwards. The results show that some spatial characteristics of an exhibition can inhibit the recall of pictures and shift the focus to perceptual salience of the artworks. PMID:25379276

  11. Vibration Analysis of a Split Path Gearbox

    NASA Technical Reports Server (NTRS)

    Krantz, Timothy L.; Rashidi, Majid

    1995-01-01

    Split path gearboxes can be attractive alternatives to the common planetary designs for rotorcraft, but because they have seen little use, they are relatively high risk designs. To help reduce the risk of fielding a rotorcraft with a split path gearbox, the vibration and dynamic characteristics of such a gearbox were studied. A mathematical model was developed by using the Lagrangian method, and it was applied to study the effect of three design variables on the natural frequencies and vibration energy of the gearbox. The first design variable, shaft angle, had little influence on the natural frequencies. The second variable, mesh phasing, had a strong effect on the levels of vibration energy, with phase angles of 0 deg and 180 deg producing low vibration levels. The third design variable, the stiffness of the shafts connecting the spur gears to the helical pinions, strongly influenced the natural frequencies of some of the vibration modes, including two of the dominant modes. We found that, to achieve the lowest level of vibration energy, the natural frequencies of these two dominant modes should be less than those of the main excitation sources.

  12. Irrational beliefs, attitudes about competition, and splitting.

    PubMed

    Watson, P J; Morris, R J; Miller, L

    2001-03-01

    Rational-Emotive Behavior Therapy (REBT) theoretically promotes actualization of both individualistic and social-oriented potentials. In a test of this assumption, the Belief Scale and subscales from the Survey of Personal Beliefs served as measures of what REBT presumes to be pathogenic irrationalities. These measures were correlated with the Hypercompetitive Attitude Scale (HCAS), the Personal Development Competitive Attitude Scale (PDCAS), factors from the Splitting Index, and self-esteem. Results for the HCAS and Self-Splitting supported the REBT claim about individualistic self-actualization. Mostly nonsignificant and a few counterintuitive linkages were observed for irrational beliefs with the PDCAS, Family-Splitting, and Other-Splitting, and these data suggested that REBT may be less successful in capturing the "rationality" of a social-oriented self-actualization. Copyright 2001 John Wiley & Sons, Inc.

  13. Novel Split Chest Tube Improves Post-Surgical Thoracic Drainage

    PubMed Central

    Olivencia-Yurvati, Albert H; Cherry, Brandon H; Gurji, Hunaid A; White, Daniel W; Newton, J Tyler; Scott, Gary F; Hoxha, Besim; Gourlay, Terence; Mallet, Robert T

    2014-01-01

    Objective Conventional, separate mediastinal and pleural tubes are often inefficient at draining thoracic effusions. Description We developed a Y-shaped chest tube with split ends that divide within the thoracic cavity, permitting separate intrathoracic placement and requiring a single exit port. In this study, thoracic drainage by the split drain vs. that of separate drains was tested. Methods After sternotomy, pericardiotomy, and left pleurotomy, pigs were fitted with separate chest drains (n=10) or a split tube prototype (n=9) with internal openings positioned in the mediastinum and in the costo-diaphragmatic recess. Separate series of experiments were conducted to test drainage of D5W or 0.58 M sucrose, an aqueous solution with viscosity approximating that of plasma. One litre of fluid was infused into the thorax, and suction was applied at −20 cm H2O for 30 min. Results When D5W was infused, the split drain left a residual volume of 53 ± 99 ml (mean value ± SD) vs. 148 ± 120 for the separate drain (P=0.007), representing a drainage efficiency (i.e. drained vol/[drained + residual vol]) of 95 ± 10% vs. 86 ± 12% for the separate drains (P = 0.011). In the second series, the split drain evacuated more 0.58 M sucrose in the first minute (967 ± 129 ml) than the separate drains (680 ± 192 ml, P<0.001). By 30 min, the split drain evacuated a similar volume of sucrose vs. the conventional drain (1089 ± 72 vs. 1056 ± 78 ml; P = 0.5). Residual volume tended to be lower (25 ± 10 vs. 62 ± 72 ml; P = 0.128) and drainage efficiency tended to be higher (98 ± 1 vs. 95 ± 6%; P = 0.111) with the split drain vs. conventional separate drains. Conclusion The split chest tube drained the thoracic cavity at least as effectively as conventional separate tubes. This new device could potentially alleviate postoperative complications. PMID:25478289

  14. Novel Split Chest Tube Improves Post-Surgical Thoracic Drainage.

    PubMed

    Olivencia-Yurvati, Albert H; Cherry, Brandon H; Gurji, Hunaid A; White, Daniel W; Newton, J Tyler; Scott, Gary F; Hoxha, Besim; Gourlay, Terence; Mallet, Robert T

    2014-01-01

    Conventional, separate mediastinal and pleural tubes are often inefficient at draining thoracic effusions. We developed a Y-shaped chest tube with split ends that divide within the thoracic cavity, permitting separate intrathoracic placement and requiring a single exit port. In this study, thoracic drainage by the split drain vs. that of separate drains was tested. After sternotomy, pericardiotomy, and left pleurotomy, pigs were fitted with separate chest drains (n=10) or a split tube prototype (n=9) with internal openings positioned in the mediastinum and in the costo-diaphragmatic recess. Separate series of experiments were conducted to test drainage of D5W or 0.58 M sucrose, an aqueous solution with viscosity approximating that of plasma. One litre of fluid was infused into the thorax, and suction was applied at -20 cm H2O for 30 min. When D5W was infused, the split drain left a residual volume of 53 ± 99 ml (mean value ± SD) vs. 148 ± 120 for the separate drain (P=0.007), representing a drainage efficiency (i.e. drained vol/[drained + residual vol]) of 95 ± 10% vs. 86 ± 12% for the separate drains (P = 0.011). In the second series, the split drain evacuated more 0.58 M sucrose in the first minute (967 ± 129 ml) than the separate drains (680 ± 192 ml, P<0.001). By 30 min, the split drain evacuated a similar volume of sucrose vs. the conventional drain (1089 ± 72 vs. 1056 ± 78 ml; P = 0.5). Residual volume tended to be lower (25 ± 10 vs. 62 ± 72 ml; P = 0.128) and drainage efficiency tended to be higher (98 ± 1 vs. 95 ± 6%; P = 0.111) with the split drain vs. conventional separate drains. The split chest tube drained the thoracic cavity at least as effectively as conventional separate tubes. This new device could potentially alleviate postoperative complications.

  15. Ductless Mini-Split Heat Pump Comfort Evaluation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roth, K.; Sehgal, N.; Akers, C.

    2013-03-01

    Field tests were conducted in two homes in Austin, TX to evaluate the comfort performance of ductless mini-split heat pumps (DMSHPs), measuring temperature and relative humidity measurements in four rooms in each home before and after retrofitting a central HVAC system with DMSHPs.

  16. Semi-analytical and Numerical Studies on the Flattened Brazilian Splitting Test Used for Measuring the Indirect Tensile Strength of Rocks

    NASA Astrophysics Data System (ADS)

    Huang, Y. G.; Wang, L. G.; Lu, Y. L.; Chen, J. R.; Zhang, J. H.

    2015-09-01

    Based on the two-dimensional elasticity theory, this study established a mechanical model under chordally opposing distributed compressive loads, in order to perfect the theoretical foundation of the flattened Brazilian splitting test used for measuring the indirect tensile strength of rocks. The stress superposition method was used to obtain the approximate analytic solutions of stress components inside the flattened Brazilian disk. These analytic solutions were then verified through a comparison with the numerical results of the finite element method (FEM). Based on the theoretical derivation, this research carried out a contrastive study on the effect of the flattened loading angles on the stress value and stress concentration degree inside the disk. The results showed that the stress concentration degree near the loading point and the ratio of compressive/tensile stress inside the disk dramatically decreased as the flattened loading angle increased, avoiding the crushing failure near-loading point of Brazilian disk specimens. However, only the tensile stress value and the tensile region were slightly reduced with the increase of the flattened loading angle. Furthermore, this study found that the optimal flattened loading angle was 20°-30°; flattened load angles that were too large or too small made it difficult to guarantee the central tensile splitting failure principle of the Brazilian splitting test. According to the Griffith strength failure criterion, the calculative formula of the indirect tensile strength of rocks was derived theoretically. This study obtained a theoretical indirect tensile strength that closely coincided with existing and experimental results. Finally, this paper simulated the fracture evolution process of rocks under different loading angles through the use of the finite element numerical software ANSYS. The modeling results showed that the Flattened Brazilian Splitting Test using the optimal loading angle could guarantee the tensile splitting failure initiated by a central crack.

  17. Split and Splice Approach for Highly Selective Targeting of Human NSCLC Tumors

    DTIC Science & Technology

    2014-10-01

    development and implementation of the “split-and- spice ” approach required optimization of many independent parameters, which were addressed in parallel...verify the feasibility of the “split and splice” approach for targeting human NSCLC tumor cell lines in culture and prepare the optimized toxins for...for cultured cells (months 2- 8). 2B. To test the efficiency of cell targeting by the toxin variants reconstituted in vitro (months 3-6). 2C. To

  18. Experimental Investigation of the Influence of Confining Stress on Hard Rock Fragmentation Using a Conical Pick

    NASA Astrophysics Data System (ADS)

    Li, Xibing; Wang, Shaofeng; Wang, Shanyong

    2018-01-01

    High geostress is a prominent condition in deep excavations and affects the cuttability of deep hard rock. This study aims to determine the influence of confining stress on hard rock fragmentation as applied by a conical pick. Using a true triaxial test apparatus, static and coupled static and dynamic loadings from pick forces were applied to end faces of cubic rock specimens to break them under biaxial, uniaxial and stress-free confining stress conditions. The cuttability indices (peak pick force, insertion depth and disturbance duration), failure patterns and fragment sizes were measured and compared to estimate the effects of confining stress. The results show that the rock cuttabilities decreased in order from rock breakages under stress-free conditions to uniaxial confining stress and then to biaxial confining stress. Under biaxial confining stress, only flake-shaped fragments were stripped from the rock surfaces under the requirements of large pick forces or disturbance durations. As the level of uniaxial confining stress increased, the peak pick force and the insertion depth initially increased and then decreased, and the failure patterns varied from splitting to partial splitting and then to rock bursts with decreasing average fragment sizes. Rock bursts will occur under elastic compression via ultra-high uniaxial confining stresses. There are two critical uniaxial confining stress levels, namely stress values at which peak pick forces begin to decrease and improve rock cuttability, and those at which rock bursts initially occur and cutting safety decreases. In particular, hard rock is easiest to split safely and efficiently under stress-free conditions. Moreover, coupled static preloading and dynamic disturbance can increase the efficiency of rock fragmentation with increasing preloading levels and disturbance amplitudes. The concluding remarks confirm hard rock cuttability using conical pick, which can improve the applicability of mechanical excavation in deep hard rock masses.

  19. SPLICEFINDER – A Fast and Easy Screening Method for Active Protein Trans-Splicing Positions

    PubMed Central

    Eppmann, Simone; Busche, Alena; Dikovskaya, Dina; Dötsch, Volker; Mootz, Henning D.

    2013-01-01

    Split intein enabled protein trans-splicing (PTS) is a powerful method for the ligation of two protein fragments, thereby paving the way for various protein modification or protein function control applications. PTS activity is strongly influenced by the amino acids directly flanking the splice junctions. However, to date no reliable prediction can be made whether or not a split intein is active in a particular foreign extein context. Here we describe SPLICEFINDER, a PCR-based method, allowing fast and easy screening for active split intein insertions in any target protein. Furthermore we demonstrate the applicability of SPLICEFINDER for segmental isotopic labeling as well as for the generation of multi-domain and enzymatically active proteins. PMID:24023792

  20. Pattern Effects of Soil on Photovoltaic Surfaces

    DOE PAGES

    Burton, Patrick D.; Hendrickson, Alex; Ulibarri, Stephen Seth; ...

    2016-06-06

    The texture or patterning of soil on PV surfaces may influence light capture at various angles of incidence (AOI). Accumulated soil can be considered a microshading element, which changes with respect to AOI. Laboratory deposition of simulated soil was used to prepare test coupons for simultaneous AOI and soiling loss experiments. A mixed solvent deposition technique was used to consistently deposit patterned test soils onto glass slides. Transmission decreased as soil loading and AOI increased. Dense aggregates significantly decreased transmission. But, highly dispersed particles are less prone to secondary scattering, improving overall light collection. In order to test AOI losses on relevant systems, uniform simulated soil coatings were applied to split reference cells to further examine this effect. Finally, the measured optical transmission and area coverage correlated closely to the observedmore » $$I_{{rm SC}}$$. Angular losses were significant at angles as low as 25°.« less

  1. On the occurrence of false positives in tests of migration under an isolation with migration model

    PubMed Central

    Hey, Jody; Chung, Yujin; Sethuraman, Arun

    2015-01-01

    The population genetic study of divergence is often done using a Bayesian genealogy sampler, like those implemented in IMa2 and related programs, and these analyses frequently include a likelihood-ratio test of the null hypothesis of no migration between populations. Cruickshank and Hahn (2014, Molecular Ecology, 23, 3133–3157) recently reported a high rate of false positive test results with IMa2 for data simulated with small numbers of loci under models with no migration and recent splitting times. We confirm these findings and discover that they are caused by a failure of the assumptions underlying likelihood ratio tests that arises when using marginal likelihoods for a subset of model parameters. We also show that for small data sets, with little divergence between samples from two populations, an excellent fit can often be found by a model with a low migration rate and recent splitting time and a model with a high migration rate and a deep splitting time. PMID:26456794

  2. 49 CFR 40.153 - How does the MRO notify employees of their right to a test of the split specimen?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... must have the ability to receive the employee's calls at all times during the 72 hour period (e.g., by use of an answering machine with a “time stamp” feature when there is no one in your office to answer... 72 hours from the time you provide this notification to him or her to request a test of the split...

  3. The role of alcohol in road traffic accidents with fatal outcome: 10-year period in Croatia Split-Dalmatia County.

    PubMed

    Sutlovic, Davorka; Scepanovic, Antonija; Bosnjak, Marinko; Versic-Bratincevic, Maja; Definis-Gojanovic, Marija

    2014-01-01

    The aim of the study was to investigate the relationship between alcohol consumption and fatal road traffic accidents that took place in Split-Dalmatia County (Croatia) during a 10-year period (from August 2001 to August 2011). A retrospective analysis of 474 autopsy reports was performed, with an emphasis on 337 toxicologal findings of blood alcohol concentration (BAC) and the mode of participation in traffic (driver, passenger, pedestrian, or cyclist). Relations between the BAC, the weekday on which death occurred, victim's age and gender, and differences according to 3 successive legislation periods within the observed time frame were analyzed. The BAC was measured by gas chromatography with headspace and flame ionization detection. Alcohol was regarded as a contributive death factor if BAC was positive; that is, higher than 0.5 g/kg. BAC was positive in 177 cases. Most often it was the car driver who had a positive BAC. Victims of traffic accidents were mostly male drivers, and those accidents were more often associated with alcohol consumption. Consumption of alcohol produced a significant increase in culpability. The results of our study show that alcohol remains one of the main contributing factors of traffic accidents in Split-Dalmatia County. Unfortunately, legislation changes regarding the allowed BAC did not cause any reduction in casualties among drivers driving under the influence of alcohol (DUIA). Chi-square test of the number of total driver victims and driver victims who were DUIA revealed no significant difference (P = .173).

  4. Fracture toughness of fibrous composite materials

    NASA Technical Reports Server (NTRS)

    Poe, C. C., Jr.

    1984-01-01

    Laminates with various proportions of 0 deg, 45 deg, and 90 deg plies were fabricated from T300/5208 and T300/BP-907 graphite/epoxy prepreg tape material. The fracture toughness of each laminate orientation or lay-up was determined by testing center-cracked specimens, and it was also predicted with the general fracture-toughness parameter. The predictions were good except when crack-tip splitting was large, at which time the toughness and strengths tended to be underpredicted. By using predictions, a parametric study was also made of factors that influence fracture toughness. Fiber and matrix properties as well as lay-up were investigated. Without crack-tip splitting, fracture toughness increases in proportion to fiber strength and fiber volume fraction, increases linearly with E(22)/E(11), is largest when the modulus for non-0 deg fibers is greater than that of 0 deg fibers, and is smallest for 0(m)/90(p)(s) lay-ups. (The E(11) and E(22) are Young's moduli of the lamina parallel to and normal to the direction of the fibers, respectively). For a given proportion of 0 deg plies, the most notch-sensitive lay-ups are 0(m)/90(p)(s) and the least sensitive are 0(m)/45(n)(s) and alpha(s). Notch sensitivity increases with the proportion of 0 deg plies and decreases with alpha. Strong, tough matrix materials, which inhibit crack-tip splitting, generally lead to minimum fracture toughness.

  5. Towards Versatile and Sustainable Hydrogen Production through Electrocatalytic Water Splitting: Electrolyte Engineering.

    PubMed

    Shinagawa, Tatsuya; Takanabe, Kazuhiro

    2017-04-10

    Recent advances in power generation from renewable resources necessitate conversion of electricity to chemicals and fuels in an efficient manner. Electrocatalytic water splitting is one of the most powerful and widespread technologies. The development of highly efficient, inexpensive, flexible, and versatile water electrolysis devices is desired. This review discusses the significance and impact of the electrolyte on electrocatalytic performance. Depending on the circumstances under which the water splitting reaction is conducted, the required solution conditions, such as the identity and molarity of ions, may significantly differ. Quantitative understanding of such electrolyte properties on electrolysis performance is effective to facilitate the development of efficient electrocatalytic systems. The electrolyte can directly participate in reaction schemes (kinetics), affect electrode stability, and/or indirectly impact the performance by influencing the concentration overpotential (mass transport). This review aims to guide fine-tuning of the electrolyte properties, or electrolyte engineering, for (photo)electrochemical water splitting reactions. © 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

  6. Joint angles of the ankle, knee, and hip and loading conditions during split squats.

    PubMed

    Schütz, Pascal; List, Renate; Zemp, Roland; Schellenberg, Florian; Taylor, William R; Lorenzetti, Silvio

    2014-06-01

    The aim of this study was to quantify how step length and the front tibia angle influence joint angles and loading conditions during the split squat exercise. Eleven subjects performed split squats with an additional load of 25% body weight applied using a barbell. Each subject's movements were recorded using a motion capture system, and the ground reaction force was measured under each foot. The joint angles and loading conditions were calculated using a cluster-based kinematic approach and inverse dynamics modeling respectively. Increases in the tibia angle resulted in a smaller range of motion (ROM) of the front knee and a larger ROM of the rear knee and hip. The external flexion moment in the front knee/hip and the external extension moment in the rear hip decreased as the tibia angle increased. The flexion moment in the rear knee increased as the tibia angle increased. The load distribution between the legs changed < 25% when split squat execution was varied. Our results describing the changes in joint angles and the resulting differences in the moments of the knee and hip will allow coaches and therapists to adapt the split squat exercise to the individual motion and load demands of athletes.

  7. Exploring factors that influence students' attitudes toward midwifery in Jordan: Measuring psychometric properties of a newly developed tool.

    PubMed

    Al Hadid, Lourance A; Al-Rajabi, Omaymah; AlBarmawi, Marwa; Yousef Sayyah, Najah Sayyah; Toqan, Lwiza Moh'd

    2018-03-01

    Students' professional choice to proceed in midwifery is influenced by many factors. This study validated an instrument developed to assess students' attitudes toward midwifery in Jordan. It also addressed the motivating and de-motivating factors influencing students' decision concerning joining and continuing in midwifery. A descriptive, cross-section study was conducted on a convenience sample of 374 midwifery students representing private, governmental, and military midwifery colleges. The researchers developed the study questionnaire through conducting a comprehensive literature review, organizing common themes and consulting experts. Exploratory factor analysis and tests of normality and reliability, including Cronbach's Alpha and Bartlett's test, were used in the analysis. The result was three factors were explained by 23 items. They were as follows: professional knowledge, professional motivation factors, and de-motivating professional factors. The first 8 items explained nearly 61% of the variance. Cronbach's Alpha was 0.834 with a range of 0.835-0.839. The Spearman-Brown coefficient was 0.81 and Guttman Split-Half coefficient was 0.83. Issues of reliability and validity require a repetitive process of testing under a range of circumstances to ensure both stability and representation of the construct. However, addressing factors found to have impact of students' decisions is crucial to improve retention of high quality students. Copyright © 2018. Published by Elsevier Ltd.

  8. Influence of CT-based depth correction of renal scintigraphy in evaluation of living kidney donors on side selection and postoperative renal function: is it necessary to know the relative renal function?

    PubMed

    Weinberger, Sarah; Klarholz-Pevere, Carola; Liefeldt, Lutz; Baeder, Michael; Steckhan, Nico; Friedersdorff, Frank

    2018-03-22

    To analyse the influence of CT-based depth correction in the assessment of split renal function in potential living kidney donors. In 116 consecutive living kidney donors preoperative split renal function was assessed using the CT-based depth correction. Influence on donor side selection and postoperative renal function of the living kidney donors were analyzed. Linear regression analysis was performed to identify predictors of postoperative renal function. A left versus right kidney depth variation of more than 1 cm was found in 40/114 donors (35%). 11 patients (10%) had a difference of more than 5% in relative renal function after depth correction. Kidney depth variation and changes in relative renal function after depth correction would have had influence on side selection in 30 of 114 living kidney donors. CT depth correction did not improve the predictability of postoperative renal function of the living kidney donor. In general, it was not possible to predict the postoperative renal function from preoperative total and relative renal function. In multivariate linear regression analysis, age and BMI were identified as most important predictors for postoperative renal function of the living kidney donors. Our results clearly indicate that concerning the postoperative renal function of living kidney donors, the relative renal function of the donated kidney seems to be less important than other factors. A multimodal assessment with consideration of all available results including kidney size, location of the kidney and split renal function remains necessary.

  9. Influence of Water Content on Mechanical Properties of Rock in Both Saturation and Drying Processes

    NASA Astrophysics Data System (ADS)

    Zhou, Zilong; Cai, Xin; Cao, Wenzhuo; Li, Xibing; Xiong, Cheng

    2016-08-01

    Water content has a pronounced influence on the properties of rock materials, which is responsible for many rock engineering hazards, such as landslides and karst collapse. Meanwhile, water injection is also used for the prevention of some engineering disasters like rock-bursts. To comprehensively investigate the effect of water content on mechanical properties of rocks, laboratory tests were carried out on sandstone specimens with different water contents in both saturation and drying processes. The Nuclear Magnetic Resonance technique was applied to study the water distribution in specimens with variation of water contents. The servo-controlled rock mechanics testing machine and Split Hopkinson Pressure Bar technique were used to conduct both compressive and tensile tests on sandstone specimens with different water contents. From the laboratory tests, reductions of the compressive and tensile strength of sandstone under static and dynamic states in different saturation processes were observed. In the drying process, all of the saturated specimens could basically regain their mechanical properties and recover its strength as in the dry state. However, for partially saturated specimens in the saturation and drying processes, the tensile strength of specimens with the same water content was different, which could be related to different water distributions in specimens.

  10. Association Splitting: A randomized controlled trial of a new method to reduce craving among inpatients with alcohol dependence.

    PubMed

    Schneider, Brooke C; Moritz, Steffen; Hottenrott, Birgit; Reimer, Jens; Andreou, Christina; Jelinek, Lena

    2016-04-30

    Association Splitting, a novel cognitive intervention, was tested in patients with alcohol dependence as an add-on intervention in an initial randomized controlled trial. Preliminary support for Association Splitting has been found in patients with obsessive-compulsive disorder, as well as in an online pilot study of patients with alcohol use disorders. The present variant sought to reduce craving by strengthening neutral associations with alcohol-related stimuli, thus, altering cognitive networks. Eighty-four inpatients with verified diagnoses of alcohol dependence, who were currently undergoing inpatient treatment, were randomly assigned to Association Splitting or Exercise Therapy. Craving was measured at baseline, 4-week follow-up, and six months later with the Obsessive-Compulsive Drinking Scale (primary outcome) and the Alcohol Craving Questionnaire. There was no advantage for Association Splitting after three treatment sessions relative to Exercise Therapy. Among Association Splitting participants, 51.9% endorsed a subjective decline in craving and 88.9% indicated that they would use Association Splitting in the future. Despite high acceptance, an additional benefit of Association Splitting beyond standard inpatient treatment was not found. Given that participants were concurrently undergoing inpatient treatment and Association Splitting has previously shown moderate effects, modification of the study design may improve the potential to detect significant effects in future trials. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  11. GASOLINE/DIESEL PM SPLIT STUDY: LIGHT-DUTY VEHICLE TESTING, DATA, AND ANALYSIS

    EPA Science Inventory

    During June 2001, the EPA participated in DOE's Gasoline/Diesel PM Split Study in Riverside, California. The purpose of the study was to determine the contribution of diesel versus gasoline-powered exhaust to the particulate matter (PM) inventory in the South Coast Air Basin. T...

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dernotte, Jeremie; Dec, John E.; Ji, Chunsheng

    A detailed understanding of the various factors affecting the trends in gross-indicated thermal efficiency with changes in key operating parameters has been carried out, applied to a one-liter displacement single-cylinder boosted Low-Temperature Gasoline Combustion (LTGC) engine. This work systematically investigates how the supplied fuel energy splits into the following four energy pathways: gross-indicated thermal efficiency, combustion inefficiency, heat transfer and exhaust losses, and how this split changes with operating conditions. Additional analysis is performed to determine the influence of variations in the ratio of specific heat capacities (γ) and the effective expansion ratio, related to the combustion-phasing retard (CA50), onmore » the energy split. Heat transfer and exhaust losses are computed using multiple standard cycle analysis techniques. Furthermore, the various methods are evaluated in order to validate the trends.« less

  13. Differences in results of analyses of concurrent and split stream-water samples collected and analyzed by the US Geological Survey and the Illinois Environmental Protection Agency, 1985-91

    USGS Publications Warehouse

    Melching, C.S.; Coupe, R.H.

    1995-01-01

    During water years 1985-91, the U.S. Geological Survey (USGS) and the Illinois Environmental Protection Agency (IEPA) cooperated in the collection and analysis of concurrent and split stream-water samples from selected sites in Illinois. Concurrent samples were collected independently by field personnel from each agency at the same time and sent to the IEPA laboratory, whereas the split samples were collected by USGS field personnel and divided into aliquots that were sent to each agency's laboratory for analysis. The water-quality data from these programs were examined by means of the Wilcoxon signed ranks test to identify statistically significant differences between results of the USGS and IEPA analyses. The data sets for constituents and properties identified by the Wilcoxon test as having significant differences were further examined by use of the paired t-test, mean relative percentage difference, and scattergrams to determine if the differences were important. Of the 63 constituents and properties in the concurrent-sample analysis, differences in only 2 (pH and ammonia) were statistically significant and large enough to concern water-quality engineers and planners. Of the 27 constituents and properties in the split-sample analysis, differences in 9 (turbidity, dissolved potassium, ammonia, total phosphorus, dissolved aluminum, dissolved barium, dissolved iron, dissolved manganese, and dissolved nickel) were statistically significant and large enough to con- cern water-quality engineers and planners. The differences in concentration between pairs of the concurrent samples were compared to the precision of the laboratory or field method used. The differences in concentration between pairs of the concurrent samples were compared to the precision of the laboratory or field method used. The differences in concentration between paris of split samples were compared to the precision of the laboratory method used and the interlaboratory precision of measuring a given concentration or property. Consideration of method precision indicated that differences between concurrent samples were insignificant for all concentrations and properties except pH, and that differences between split samples were significant for all concentrations and properties. Consideration of interlaboratory precision indicated that the differences between the split samples were not unusually large. The results for the split samples illustrate the difficulty in obtaining comparable and accurate water-quality data.

  14. Visuospatial asymmetries and interocular transfer in the split-brain rat.

    PubMed

    Adelstein, A; Crowne, D P

    1991-06-01

    Interocular transfer (IOT), hemispheric superiority, and cerebral dominance were examined in split-brain female albino rats. Callosum-sectioned and intact animals were monocularly trained in the Morris water maze and tested in IOT and reversal phases. In the IOT phase, split-brain rats entered more nontarget quadrants and headed less accurately toward the platform than did controls. For both split-brain animals and controls, right-eye training resulted in shorter latencies and fewer nontarget entries than did left-eye training. Analyses of cerebral dominance showed shorter latencies and smaller heading errors over all 3 phases in rats that were trained with the nondominant eye. Right-eye dominant controls were less affected by platform reversal. Split-brain rats were inferior to controls in latency to find the platform and in target quadrant entries. This finding establishes a spatial cognitive deficit from callosum section.

  15. A new index for the wintertime southern hemispheric split jet

    NASA Astrophysics Data System (ADS)

    Babian, Stella; Grieger, Jens; Cubasch, Ulrich

    2018-05-01

    One of the most prominent asymmetric features of the southern hemispheric (SH) circulation is the split jet over Australia and New Zealand in austral winter. Previous studies have developed indices to detect the degree to which the upper-level midlatitude westerlies are split and investigated the relationship between split events and the low-frequency teleconnection patterns, viz. the Antarctic Oscillation (AAO) and the El Niño-Southern Oscillation (ENSO). As the results were inconsistent, the relationship between the wintertime SH split jet and the climate variability indices remains unresolved and is the focus of this study. Until now, all split indices' definitions were based on the specific region where the split jet is recognizable. We consider the split jet as hemispheric rather than a regional feature and propose a new, hemispherical index that is based on the principal components (PCs) of the zonal wind field for the SH winter. A linear combination of PC2 and PC3 of the anomalous monthly (JAS) zonal wind is used to identify split-jet conditions. In a subsequent correlation analysis, our newly defined PC-based split index (PSI) indicates a strong coherence with the AAO. However, this significant relationship is unstable over the analysis period; during the 1980s, the AAO amplitude was higher than the PSI, and vice versa in the 1990s. It is probable that the PSI, as well as the AAO, underlie low-frequency variability on the decadal to centennial timescales, but the analyzed period is too short to draw these conclusions. A regression analysis with the Multivariate ENSO Index points to a nonlinear relationship between PSI and ENSO; i.e., split jets occur during both strong positive and negative phases of ENSO but rarely under normal conditions. The Pacific South American (PSA) patterns, defined as the second and third modes of the geopotential height variability at 500 hPa, correlate poorly with the PSI (rPSA - 1 ≈ 0.2 and rPSA - 2 = 0.06), but significantly with the individual components (PCs) of the PSI, revealing an indirect influence on the SH split-jet variability. Our study suggests that the wintertime SH split jet is strongly associated with the AAO, while ENSO is to a lesser extent connected to the PSI. We conclude that a positive AAO phase, as well as both flavors of ENSO and the PSA-1 pattern produce favorable conditions for a SH split event.

  16. Alternative Refrigerant Evaluation for High-Ambient Temperature Environments: R-22 and R-410A Alternatives for Mini-Split Air Conditioners

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abdelaziz, Omar; Munk, Jeffrey D.; Shrestha, Som S.

    The Oak Ridge National Laboratory (ORNL) High-Ambient Temperature Testing Program for Low-GWP Refrigerants aims to develop an understanding of the performance of low-Global Warming Potential (low-GWP) alternatives to Hydrochlorofluorocarbon (HCFC) and Hydrofluorocarbon (HFC) refrigerants in mini-split air conditioners under high ambient temperature conditions. This interim working paper describes the parties involved, the alternative refrigerants selection process, the test procedures, and the preliminary results.

  17. An Empirical Study of Re-sampling Techniques as a Method for Improving Error Estimates in Split-plot Designs

    DTIC Science & Technology

    2010-03-01

    sufficient replications often lead to models that lack precision in error estimation and thus imprecision in corresponding conclusions. This work develops...v Preface This work is dedicated to all who gave and continue to give in order for me to achieve some semblance of success. Benjamin M. Lee vi...develop, examine and test methodologies for an- alyzing test results from split-plot designs. In particular, this work determines the applicability

  18. The design of a small linear-resonant, split Stirling cryogenic refrigerator compressor

    NASA Technical Reports Server (NTRS)

    Ackermann, R. A.

    1985-01-01

    The development of a small linear-resonant compressor for use in a 1/4-watt, 78K, split Stirling cryogenic refrigerator is discussed. The compressor contains the following special features: (1) a permanent-magnet linear motor; (2) resonant dynamics; (3) dynamic balancing; and (4) a close-clearance seal between the compressor piston and cylinder. This paper describes the design of the compressor, and presents component test data and system test data for the compressor driving a 1/4-watt expander.

  19. Effects of Rashba spin-orbit coupling, Zeeman splitting and gyrotropy in two-dimensional cavity polaritons under the influence of the Landau quantization

    NASA Astrophysics Data System (ADS)

    Moskalenko, Sveatoslav A.; Podlesny, Igor V.; Dumanov, Evgheni V.; Liberman, Michael A.

    2015-09-01

    We consider the energy spectrum of the two-dimensional cavity polaritons under the influence of a strong magnetic and electric fields perpendicular to the surface of the GaAs-type quantum wells (QWs) with p-type valence band embedded into the resonators. As the first step in this direction the Landau quantization (LQ) of the electrons and heavy-holes (hh) was investigated taking into account the Rashba spin-orbit coupling (RSOC) with third-order chirality terms for hh and with nonparabolicity terms in their dispersion low including as well the Zeeman splitting (ZS) effects. The nonparabolicity term is proportional to the strength of the electric field and was introduced to avoid the collapse of the semiconductor energy gap under the influence of the third order chirality terms. The exact solutions for the eigenfunctions and eigenenergies were obtained using the Rashba method [E.I. Rashba, Fiz. Tverd. Tela 2, 1224 (1960) [Sov. Phys. Solid State 2, 1109 (1960)

  20. Hemispheric specialisation for imitation of hand-head positions and finger configurations: a controlled study in patients with complete callosotomy.

    PubMed

    Lausberg, Hedda; Cruz, Robyn Flaum

    2004-01-01

    Several studies of patients with unilateral brain damage and a patient with spontaneous callosal disconnection [Journal of Neurology, Neurosurgery, and Psychiatry 61 (1996) 176; Neuropsychologia 37 (1999) 559; Neuropsychologia 39 (2001) 1432] suggest that the imitation of positions of the hand relative to the head is a strongly lateralised left hemispheric function. In contrast, the imitation of finger configurations draws on resources of both hemispheres with a predominance of the right hemisphere. While these findings suggest a specific pattern of imitation impairment in split-brain patients, thus far, no imitation deficits have been reported in split-brain patients. Three patients with complete callosotomy and two control groups, four patients with partial callosotomy and 10 healthy subjects, imitated hand-head positions and finger configurations with non-lateralised and tachistoscopic stimulus presentation. In addition, the influence of visual control on the imitation performance was examined. One split-brain patient showed the predicted dissociation as she had severe right hemispheric deficit in imitating hand-head positions, while finger configuration imitation was preserved. The other two split-brain patients had no impairment in hand-head position imitation. Withdrawal of visual control significantly deteriorated imitation of finger configurations in the split-brain group, but not in the controls, demonstrating that the split-brain patients relied heavily on visual control as a compensatory strategy indicating an imitation deficit in the separate hemispheres. The findings question the previously held belief that in split-brain patients both hemispheres are perfectly capable of imitating gestures and that imitation is not dependent on hemispherically specialised functions.

  1. A cooperative-binding split aptamer assay for rapid, specific and ultra-sensitive fluorescence detection of cocaine in saliva.

    PubMed

    Yu, Haixiang; Canoura, Juan; Guntupalli, Bhargav; Lou, Xinhui; Xiao, Yi

    2017-01-01

    Sensors employing split aptamers that reassemble in the presence of a target can achieve excellent specificity, but the accompanying reduction of target affinity mitigates any overall gains in sensitivity. We for the first time have developed a split aptamer that achieves enhanced target-binding affinity through cooperative binding. We have generated a split cocaine-binding aptamer that incorporates two binding domains, such that target binding at one domain greatly increases the affinity of the second domain. We experimentally demonstrate that the resulting cooperative-binding split aptamer (CBSA) exhibits higher target binding affinity and is far more responsive in terms of target-induced aptamer assembly compared to the single-domain parent split aptamer (PSA) from which it was derived. We further confirm that the target-binding affinity of our CBSA can be affected by the cooperativity of its binding domains and the intrinsic affinity of its PSA. To the best of our knowledge, CBSA-5335 has the highest cocaine affinity of any split aptamer described to date. The CBSA-based assay also demonstrates excellent performance in target detection in complex samples. Using this CBSA, we achieved specific, ultra-sensitive, one-step fluorescence detection of cocaine within fifteen minutes at concentrations as low as 50 nM in 10% saliva without signal amplification. This limit of detection meets the standards recommended by the European Union's Driving under the Influence of Drugs, Alcohol and Medicines program. Our assay also demonstrates excellent reproducibility of results, confirming that this CBSA-platform represents a robust and sensitive means for cocaine detection in actual clinical samples.

  2. Application of a Split-Fiber Probe to Velocity Measurement in the NASA Research Compressor

    NASA Technical Reports Server (NTRS)

    Lepicovsky, Jan

    2003-01-01

    A split-fiber probe was used to acquire unsteady data in a research compressor. The probe has two thin films deposited on a quartz cylinder 200 microns in diameter. A split-fiber probe allows simultaneous measurement of velocity magnitude and direction in a plane that is perpendicular to the sensing cylinder, because it has its circumference divided into two independent parts. Local heat transfer considerations indicated that the probe direction characteristic is linear in the range of flow incidence angles of +/- 35. Calibration tests confirmed this assumption. Of course, the velocity characteristic is nonlinear as is typical in thermal anemometry. The probe was used extensively in the NASA Glenn Research Center (GRC) low-speed, multistage axial compressor, and worked reliably during a test program of several months duration. The velocity and direction characteristics of the probe showed only minute changes during the entire test program. An algorithm was developed to decompose the probe signals into velocity magnitude and velocity direction. The averaged unsteady data were compared with data acquired by pneumatic probes. An overall excellent agreement between the averaged data acquired by a split-fiber probe and a pneumatic probe boosts confidence in the reliability of the unsteady content of the split-fiber probe data. To investigate the features of unsteady data, two methods were used: ensemble averaging and frequency analysis. The velocity distribution in a rotor blade passage was retrieved using the ensemble averaging method. Frequencies of excitation forces that may contribute to high cycle fatigue problems were identified by applying a fast Fourier transform to the absolute velocity data.

  3. Multi-Reader ROC studies with Split-Plot Designs: A Comparison of Statistical Methods

    PubMed Central

    Obuchowski, Nancy A.; Gallas, Brandon D.; Hillis, Stephen L.

    2012-01-01

    Rationale and Objectives Multi-reader imaging trials often use a factorial design, where study patients undergo testing with all imaging modalities and readers interpret the results of all tests for all patients. A drawback of the design is the large number of interpretations required of each reader. Split-plot designs have been proposed as an alternative, in which one or a subset of readers interprets all images of a sample of patients, while other readers interpret the images of other samples of patients. In this paper we compare three methods of analysis for the split-plot design. Materials and Methods Three statistical methods are presented: Obuchowski-Rockette method modified for the split-plot design, a newly proposed marginal-mean ANOVA approach, and an extension of the three-sample U-statistic method. A simulation study using the Roe-Metz model was performed to compare the type I error rate, power and confidence interval coverage of the three test statistics. Results The type I error rates for all three methods are close to the nominal level but tend to be slightly conservative. The statistical power is nearly identical for the three methods. The coverage of 95% CIs fall close to the nominal coverage for small and large sample sizes. Conclusions The split-plot MRMC study design can be statistically efficient compared with the factorial design, reducing the number of interpretations required per reader. Three methods of analysis, shown to have nominal type I error rate, similar power, and nominal CI coverage, are available for this study design. PMID:23122570

  4. Multi-reader ROC studies with split-plot designs: a comparison of statistical methods.

    PubMed

    Obuchowski, Nancy A; Gallas, Brandon D; Hillis, Stephen L

    2012-12-01

    Multireader imaging trials often use a factorial design, in which study patients undergo testing with all imaging modalities and readers interpret the results of all tests for all patients. A drawback of this design is the large number of interpretations required of each reader. Split-plot designs have been proposed as an alternative, in which one or a subset of readers interprets all images of a sample of patients, while other readers interpret the images of other samples of patients. In this paper, the authors compare three methods of analysis for the split-plot design. Three statistical methods are presented: the Obuchowski-Rockette method modified for the split-plot design, a newly proposed marginal-mean analysis-of-variance approach, and an extension of the three-sample U-statistic method. A simulation study using the Roe-Metz model was performed to compare the type I error rate, power, and confidence interval coverage of the three test statistics. The type I error rates for all three methods are close to the nominal level but tend to be slightly conservative. The statistical power is nearly identical for the three methods. The coverage of 95% confidence intervals falls close to the nominal coverage for small and large sample sizes. The split-plot multireader, multicase study design can be statistically efficient compared to the factorial design, reducing the number of interpretations required per reader. Three methods of analysis, shown to have nominal type I error rates, similar power, and nominal confidence interval coverage, are available for this study design. Copyright © 2012 AUR. All rights reserved.

  5. TOTAL ORE PROCESSING INTEGRATION AND MANAGEMENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leslie Gertsch; Richard Gertsch

    2005-05-16

    The lessons learned from ore segregation test No.3 were presented to Minntac Mine personnel during the reporting period. Ore was segregated by A-Factor, with low values going to Step 1/2 and high values going to Step 3. During the test, the mine maintained the best split possible for the given production and location constraints. During the test, Step 1&2 A-Factor was lowered more than Step 3 was raised. All other ore quality changes were not manipulated, but the segregation by A-Factor affected most of the other qualities. Magnetic iron, coarse tails, fine tails, silica, and grind changed in response tomore » the split. Segregation was achieved by adding ore from HIS to the Step 3 blend and lowering the amount of LC 1&2 and somewhat lowering the amount of LC 3&4. Conversely, Step 1&2 received less HIS with a corresponding increase in LC 1&2. The amount of IBC was increased to both Steps about one-third of the way into the test. For about the center half of the test, LC 3&4 was reduced to both Steps. The most noticeable layer changes were, then: an increase in the HIS split; a decrease in the LC 1&2 split; adding IBC to both Steps; and lowering LC 3&4 to both Steps. Statistical analysis of the dataset collected during ordinary, non-segregated operation of the mine and mill is continuing. Graphical analysis of blast patterns according to drill monitor data was slowed by student classwork. It is expected to resume after the semester ends in May.« less

  6. Exploratory development of a twin-spool turbocharger for a high-output diesel engine. Final report, September 1983-June 1986

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hess, R.; King, J.F.; Harp, J.L.

    1986-08-01

    The analysis, design, fabrication, and experimental testing of a twin-spool turbocharger was conducted for the Cummins NTC-475 diesel engine. Two major designs of the twin-spool turbocharger were fabricated and tested: 1) Compact design, concentric shaft-to-shaft bearing coupled turbocharger incorporating a) split 40/sup 0/ backswept impeller, b) split AiResearch Ti8A85 turbine rotor, c) adjustable vaned compressor diffuser, and d) nozzleless AiResearch turbine (volute) housing; and 2) Independently supported (shafts dynamically de-coupled) concentric shaft design incorporating a) separate structures for bearing support of the inner shaft b) split 25/sup 0/ backswept compressor impeller, c) split T18A40/Ti8A85 turbine rotor/exducer combination, and d) dividedmore » volute, adjustable-nozzle turbine housing. While bench tests were performed on both designs, engine testing was successfully carried out using the latter designs. Tests indicated that the second twin-spool configuration gave performance comparable to the originally equipped two-stage turbocharger system of the NTC-475 diesel engine (rated BHP of 425 hp at 2100 RPM, best BSFC of 0.35 at engine lug) with the added benefit of extending engine lugging range to 1200 RPM (from 1300 RPM, as originally equipped). This configuration gave peak compressor efficiency of about 75% and peak turbine efficiency of about 80%, both attributed to the reduction inducer angle of attack and exducer exit swirl angle made possible by the twin-spool concept.« less

  7. Evolution, biogeography, and systematics of Puriana: evolution and speciation in Ostracoda, III.

    USGS Publications Warehouse

    Cronin, T. M.

    1987-01-01

    Three types of geographic isolation - land barriers, deep water barriers, and climatic barriers - resulted in three distinct evolutionary responses in Neogene and Quaternary species of the epineritic ostracode genus Puriana. Through systematic, paleobiogeographic, and morphologic study of several hundred fossil and Recent populations from the eastern Pacific, western Atlantic, Gulf of Mexico, and the Caribbean, the phylogeny of the genus and the geography of speciation events were determined. Isolation of large populations by the Isthumus of Panama during the Pliocene did not lead to lineage splitting in species known to have existed before the Isthmus formed. Conversely, the establishment of small isolated populations on Caribbean islands by passive dispersal mechanisms frequently led to the evolution of new species or subspecies. Climatic changes along the southeastern United States during the Pliocene also catalyzed possible parapatric speciation as populations that immigrated to the northeastern periphery of the genus' range split to form new species. The results provide evidence that evolutionary models describing the influence of abiotic events on patterns of evolution and speciation can be tested using properly selected tectonic and climatic events and fossil groups amenable to species-level analysis. Two new species, P. bajaensis and P. paikensis, are described. -Author

  8. L2 Fluency as Influenced by Content Familiarity and Planning: Performance, Measurement, and Pedagogy

    ERIC Educational Resources Information Center

    Bui, Gavin; Huang, Zeping

    2018-01-01

    This study investigates how second language (L2) fluency is influenced by two factors: Pre-task planning and content familiarity. Planning was adopted as a between-participant variable, combined with content familiarity as a within-participant variable, in a 2 × 2 split-plot factorial design. Nineteen measures of fluency phenomena, constituting…

  9. The effectiveness of computer reminders versus postal reminders for improving quality assessment for point-of-care testing in primary care: a randomized controlled trial.

    PubMed

    Siersma, Volkert; Kousgaard, Marius Brostrøm; Reventlow, Susanne; Ertmann, Ruth; Felding, Peter; Waldorff, Frans Boch

    2015-02-01

    This study aimed to evaluate the relative effectiveness of electronic and postal reminders for increasing adherence to the quality assurance programme for the international normalized ratio (INR) point-of-care testing (POCT) device in primary care. All 213 family practices that use the Elective Laboratory of the Capital Region, Denmark, and regularly conduct INR POCT were randomly allocated into two similarly sized groups. During the 4-month intervention, these practices were sent either computer reminders (ComRem) or computer-generated postal reminders (Postal) if they did not perform a split test to check the quality of their INR POCT for each calendar month. The adherence of the practices was tracked during the subsequent 8 months subdivided into two 4-month periods both without intervention. Outcomes were measures of split test procedure adherence. Both interventions were associated with an increase in adherence to the split test procedure - a factor 6.00 [95% confidence interval (CI) 4.46-7.72] and 8.22 [95% CI 5.87-11.52] for ComRem and Postal, respectively - but there is no evidence that one of the interventions was more effective than the other. In the ComRem group, the expected number of split tests (out of four) was 2.54 (95% CI 2.33-2.76) versus 2.44 (95% CI 2.24-2.65) in the Postal group, P = 0.14. There was a slight decrease in adherence over the two follow-ups, but neither intervention was better than the other in achieving a lasting improvement in adherence. Computer reminders are as efficient as postal reminders in increasing adherence to a quality assurance programme for the INR POCT device in primary care. © 2014 John Wiley & Sons, Ltd.

  10. The price of racial bias: intergroup negotiations in the ultimatum game.

    PubMed

    Kubota, Jennifer T; Li, Jian; Bar-David, Eyal; Banaji, Mahzarin R; Phelps, Elizabeth A

    2013-12-01

    Existing stereotypes about Black Americans may influence perceptions of intent during financial negotiations. In this study, we explored whether the influence of race on economic decisions extends to choices that are costly to the decision maker. We investigated whether racial group membership contributes to differential likelihood of rejection of objectively equal unfair monetary offers. In the Ultimatum Game, players accept or reject proposed splits of money. Players keep accepted splits, but if a player rejects an offer, both the player and the proposer receive nothing. We found that participants accepted more offers and lower offer amounts from White proposers than from Black proposers, and that this pattern was accentuated for participants with higher implicit race bias. These findings indicate that participants are willing to discriminate against Black proposers even at a cost to their own financial gain.

  11. The Price of Racial Bias: Intergroup Negotiations in the Ultimatum Game

    PubMed Central

    Kubota, Jennifer T.; Li, Jian; Bar-David, Eyal; Banaji, Mahzarin R.; Phelps, Elizabeth A.

    2014-01-01

    Existing stereotypes about Black Americans may influence perceptions of intent during financial negotiations. In this study, we explored whether the influence of race on economic decisions extends to choices that are costly to the decision maker. We investigated whether racial group membership contributes to differential likelihood of rejection of objectively equal unfair monetary offers. In the Ultimatum Game, players accept or reject proposed splits of money. Players keep accepted splits, but if a player rejects an offer, both the player and the proposer receive nothing. We found that participants accepted more offers and lower offer amounts from White proposers than from Black proposers, and that this pattern was accentuated for participants with higher implicit race bias. These findings indicate that participants are willing to discriminate against Black proposers even at a cost to their own financial gain. PMID:24121413

  12. Study on frequency characteristics of wireless power transmission system based on magnetic coupling resonance

    NASA Astrophysics Data System (ADS)

    Liang, L. H.; Liu, Z. Z.; Hou, Y. J.; Zeng, H.; Yue, Z. K.; Cui, S.

    2017-11-01

    In order to study the frequency characteristics of the wireless energy transmission system based on the magnetic coupling resonance, a circuit model based on the magnetic coupling resonant wireless energy transmission system is established. The influence of the load on the frequency characteristics of the wireless power transmission system is analysed. The circuit coupling theory is used to derive the minimum load required to suppress frequency splitting. Simulation and experimental results verify that when the load size is lower than a certain value, the system will appear frequency splitting, increasing the load size can effectively suppress the frequency splitting phenomenon. The power regulation scheme of the wireless charging system based on magnetic coupling resonance is given. This study provides a theoretical basis for load selection and power regulation of wireless power transmission systems.

  13. First-principles study of Au-decorated carbon nanotubes

    NASA Astrophysics Data System (ADS)

    Ju, Weiwei; Li, Tongwei; Zhou, Qingxiao; Li, Haisheng; Li, Xiaohong

    2018-07-01

    The electronic structures and spin-orbit (SO) coupling of carbon nanotubes with adsorbed Au atoms are investigated based on density functional theory. Three kinds of zigzag single-walled CNT (8,0), (10,0) and (12,0) are selected. The Au atoms prefer to adsorb on the top of C atoms. The adsorption of Au atoms can introduce impurity states in the band gap, modifying the electronic properties of systems. Furthermore, the influence of SO coupling on these impurity states is also explored. Considerable SO splitting (∼130 meV) can be obtained. We find that the SO splitting decreases with the increase of the concentration of Au atoms, which can be ascribed to the interaction between Au atoms, suppressing the SO splitting. Our work provides imperative understanding on the electronic properties and SO coupling effect in Au-decorated CNTs.

  14. A Structure Design Method for Reduction of MRI Acoustic Noise.

    PubMed

    Nan, Jiaofen; Zong, Nannan; Chen, Qiqiang; Zhang, Liangliang; Zheng, Qian; Xia, Yongquan

    2017-01-01

    The acoustic problem of the split gradient coil is one challenge in a Magnetic Resonance Imaging and Linear Accelerator (MRI-LINAC) system. In this paper, we aimed to develop a scheme to reduce the acoustic noise of the split gradient coil. First, a split gradient assembly with an asymmetric configuration was designed to avoid vibration in same resonant modes for the two assembly cylinders. Next, the outer ends of the split main magnet were constructed using horn structures, which can distribute the acoustic field away from patient region. Finally, a finite element method (FEM) was used to quantitatively evaluate the effectiveness of the above acoustic noise reduction scheme. Simulation results found that the noise could be maximally reduced by 6.9 dB and 5.6 dB inside and outside the central gap of the split MRI system, respectively, by increasing the length of one gradient assembly cylinder by 20 cm. The optimized horn length was observed to be 55 cm, which could reduce noise by up to 7.4 dB and 5.4 dB inside and outside the central gap, respectively. The proposed design could effectively reduce the acoustic noise without any influence on the application of other noise reduction methods.

  15. Advanced emergency braking under split friction conditions and the influence of a destabilising steering wheel torque

    NASA Astrophysics Data System (ADS)

    Tagesson, Kristoffer; Cole, David

    2017-07-01

    The steering system in most heavy trucks is such that it causes a destabilising steering wheel torque when braking on split friction, that is, different friction levels on the two sides of the vehicle. Moreover, advanced emergency braking systems are now mandatory in most heavy trucks, making vehicle-induced split friction braking possible. This imposes higher demands on understanding how the destabilising steering wheel torque affects the driver, which is the focus here. Firstly, an experiment has been carried out involving 24 subjects all driving a truck where automatic split friction braking was emulated. Secondly, an existing driver-vehicle model has been adapted and implemented to improve understanding of the observed outcome. A common conclusion drawn, after analysing results, is that the destabilising steering wheel torque only has a small effect on the motion of the vehicle. The underlying reason is a relatively slow ramp up of the disturbance in comparison to the observed cognitive delay amongst subjects; also the magnitude is low and initially suppressed by passive driver properties.

  16. Thermalization dynamics of two correlated bosonic quantum wires after a split

    NASA Astrophysics Data System (ADS)

    Huber, Sebastian; Buchhold, Michael; Schmiedmayer, Jörg; Diehl, Sebastian

    2018-04-01

    Cherently splitting a one-dimensional Bose gas provides an attractive, experimentally established platform to investigate many-body quantum dynamics. At short enough times, the dynamics is dominated by the dephasing of single quasiparticles, and well described by the relaxation towards a generalized Gibbs ensemble corresponding to the free Luttinger theory. At later times on the other hand, the approach to a thermal Gibbs ensemble is expected for a generic, interacting quantum system. Here, we go one step beyond the quadratic Luttinger theory and include the leading phonon-phonon interactions. By applying kinetic theory and nonequilibrium Dyson-Schwinger equations, we analyze the full relaxation dynamics beyond dephasing and determine the asymptotic thermalization process in the two-wire system for a symmetric splitting protocol. The major observables are the different phonon occupation functions and the experimentally accessible coherence factor, as well as the phase correlations between the two wires. We demonstrate that, depending on the splitting protocol, the presence of phonon collisions can have significant influence on the asymptotic evolution of these observables, which makes the corresponding thermalization dynamics experimentally accessible.

  17. 76 FR 34685 - Energy Conservation Program for Certain Commercial and Industrial Equipment: Decision and Order...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    .... The waiver is specific to the Daikin VRV III-PB variable refrigerant flow (VRF) multi-split commercial... this notice to test and rate its VRV III-PB variable refrigerant flow (VRF) multi-split commercial heat... Institute (ANSI/ AHRI) Standard 1230-2010, ``Performance Rating of Variable Refrigerant Flow (VRF) Multi...

  18. Emergence of the interplay between hierarchy and contact splitting in biological adhesion highlighted through a hierarchical shear lag model.

    PubMed

    Brely, Lucas; Bosia, Federico; Pugno, Nicola M

    2018-06-20

    Contact unit size reduction is a widely studied mechanism as a means to improve adhesion in natural fibrillar systems, such as those observed in beetles or geckos. However, these animals also display complex structural features in the way the contact is subdivided in a hierarchical manner. Here, we study the influence of hierarchical fibrillar architectures on the load distribution over the contact elements of the adhesive system, and the corresponding delamination behaviour. We present an analytical model to derive the load distribution in a fibrillar system loaded in shear, including hierarchical splitting of contacts, i.e. a "hierarchical shear-lag" model that generalizes the well-known shear-lag model used in mechanics. The influence on the detachment process is investigated introducing a numerical procedure that allows the derivation of the maximum delamination force as a function of the considered geometry, including statistical variability of local adhesive energy. Our study suggests that contact splitting generates improved adhesion only in the ideal case of extremely compliant contacts. In real cases, to produce efficient adhesive performance, contact splitting needs to be coupled with hierarchical architectures to counterbalance high load concentrations resulting from contact unit size reduction, generating multiple delamination fronts and helping to avoid detrimental non-uniform load distributions. We show that these results can be summarized in a generalized adhesion scaling scheme for hierarchical structures, proving the beneficial effect of multiple hierarchical levels. The model can thus be used to predict the adhesive performance of hierarchical adhesive structures, as well as the mechanical behaviour of composite materials with hierarchical reinforcements.

  19. Can Pacing Be Regulated by Post-Activation Potentiation? Insights from a Self-Paced 30 km Trial in Half-Marathon Runners

    PubMed Central

    Del Rosso, Sebastián; Barros, Edilberto; Tonello, Laís; Oliveira-Silva, Iransé; Behm, David G.; Foster, Carl; Boullosa, Daniel A.

    2016-01-01

    Purpose Given the co-existence of post-activation potentiation (PAP) and fatigue within muscle, it is not known whether PAP could influence performance and pacing during distance running by moderating fatigue. The aim of this study was to assess the influence of PAP on pacing, jumping and other physiological measures during a self-paced 30 km trial. Methods Eleven male endurance-trained runners (half-marathon runners) volunteered to participate in this study. Runners participated in a multi-stage 30 km trial. Before the trial started, determination of baseline blood lactate (bLa) and countermovement jump (CMJ) height was performed. The self-paced 30 km trial consisted of 6 × 5 km splits. At the end of each 5 km split (60 s break), data on time to complete the split, CMJ height, Rating of Perceived Exertion (RPE) and blood lactate were collected while heart rate was continuously monitored. Results There was a significant decrease in speed (e.g. positive pacing strategy after the 4th split, p<0.05) with a progressive increase in RPE throughout the trial. Compared with baseline, CMJ height was significantly (p<0.05) greater than baseline and was maintained until the end of the trial with an increase after the 5th split, concomitant with a significant reduction in speed and an increase in RPE. Significant correlations were found between ΔCMJ and ΔSPEED (r = 0.77 to 0.87, p<0.05) at different time points as well as between RPE and speed (r = -0.61 to -0.82, p<0.05). Conclusion Our results indicates that fatigue and potentiation co-exist during long lasting endurance events, and that the observed increase in jump performance towards the end of the trial could be reflecting a greater potentiation potentially perhaps counteracting the effects of fatigue and preventing further reductions in speed. PMID:26934357

  20. Visual Acuity Improvement in Continuous vs Divided Occlusion in Anisometropic Amblyopia

    PubMed Central

    Irfani, Irawati; Feriyanto, Feri; Oktarima, Primawita; Kartasasmita, Arief

    2018-01-01

    Purpose: To compare visual acuity improvement between continuous and split part-time occlusion for the treatment of moderate and severe anisometropic amblyopia. Methods: Randomised clinical trials in 6 – 13 y.o children with moderate and severe anisometropic amblyopia. Each patient was consecutively selected with continuous or split part-time occlusion. Best corrected visual acuity’s improvement was followed up to six weeks and statistical data were analyzed using chi square and unpaired t-test. Results: Best corrected visual acuity’s improvement was comparable between continuous and split part-time occlusion (0.20±0.27 vs 0.21±0.25; p = 0.79). Conclusion: Split part-time occlusion may be considered as an alternative treatment for moderate and severe anisometropic amblyopia treatment. PMID:29515681

  1. Unbiased split variable selection for random survival forests using maximally selected rank statistics.

    PubMed

    Wright, Marvin N; Dankowski, Theresa; Ziegler, Andreas

    2017-04-15

    The most popular approach for analyzing survival data is the Cox regression model. The Cox model may, however, be misspecified, and its proportionality assumption may not always be fulfilled. An alternative approach for survival prediction is random forests for survival outcomes. The standard split criterion for random survival forests is the log-rank test statistic, which favors splitting variables with many possible split points. Conditional inference forests avoid this split variable selection bias. However, linear rank statistics are utilized by default in conditional inference forests to select the optimal splitting variable, which cannot detect non-linear effects in the independent variables. An alternative is to use maximally selected rank statistics for the split point selection. As in conditional inference forests, splitting variables are compared on the p-value scale. However, instead of the conditional Monte-Carlo approach used in conditional inference forests, p-value approximations are employed. We describe several p-value approximations and the implementation of the proposed random forest approach. A simulation study demonstrates that unbiased split variable selection is possible. However, there is a trade-off between unbiased split variable selection and runtime. In benchmark studies of prediction performance on simulated and real datasets, the new method performs better than random survival forests if informative dichotomous variables are combined with uninformative variables with more categories and better than conditional inference forests if non-linear covariate effects are included. In a runtime comparison, the method proves to be computationally faster than both alternatives, if a simple p-value approximation is used. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  2. Influence of Rapid Freeze-Thaw Cycling on the Mechanical Properties of Sustainable Strain-Hardening Cement Composite (2SHCC)

    PubMed Central

    Jang, Seok-Joon; Rokugo, Keitetsu; Park, Wan-Shin; Yun, Hyun-Do

    2014-01-01

    This paper provides experimental results to investigate the mechanical properties of sustainable strain-hardening cement composite (2SHCC) for infrastructures after freeze-thaw actions. To improve the sustainability of SHCC materials in this study, high energy-consumptive components—silica sand, cement, and polyvinyl alcohol (PVA) fibers—in the conventional SHCC materials are partially replaced with recycled materials such as recycled sand, fly ash, and polyethylene terephthalate (PET) fibers, respectively. To investigate the mechanical properties of green SHCC that contains recycled materials, the cement, PVA fiber and silica sand were replaced with 10% fly ash, 25% PET fiber, and 10% recycled aggregate based on preliminary experimental results for the development of 2SHCC material, respectively. The dynamic modulus of elasticity and weight for 2SHCC material were measured at every 30 cycles of freeze-thaw. The effects of freeze-thaw cycles on the mechanical properties of sustainable SHCC are evaluated by conducting compressive tests, four-point flexural tests, direct tensile tests and prism splitting tests after 90, 180, and 300 cycles of rapid freeze-thaw. Freeze-thaw testing was conducted according to ASTM C 666 Procedure A. Test results show that after 300 cycles of freezing and thawing actions, the dynamic modulus of elasticity and mass loss of damaged 2SHCC were similar to those of virgin 2SHCC, while the freeze-thaw cycles influence mechanical properties of the 2SHCC material except for compressive behavior. PMID:28788522

  3. Tantalum-based semiconductors for solar water splitting.

    PubMed

    Zhang, Peng; Zhang, Jijie; Gong, Jinlong

    2014-07-07

    Solar energy utilization is one of the most promising solutions for the energy crises. Among all the possible means to make use of solar energy, solar water splitting is remarkable since it can accomplish the conversion of solar energy into chemical energy. The produced hydrogen is clean and sustainable which could be used in various areas. For the past decades, numerous efforts have been put into this research area with many important achievements. Improving the overall efficiency and stability of semiconductor photocatalysts are the research focuses for the solar water splitting. Tantalum-based semiconductors, including tantalum oxide, tantalate and tantalum (oxy)nitride, are among the most important photocatalysts. Tantalum oxide has the band gap energy that is suitable for the overall solar water splitting. The more negative conduction band minimum of tantalum oxide provides photogenerated electrons with higher potential for the hydrogen generation reaction. Tantalates, with tunable compositions, show high activities owning to their layered perovskite structure. (Oxy)nitrides, especially TaON and Ta3N5, have small band gaps to respond to visible-light, whereas they can still realize overall solar water splitting with the proper positions of conduction band minimum and valence band maximum. This review describes recent progress regarding the improvement of photocatalytic activities of tantalum-based semiconductors. Basic concepts and principles of solar water splitting will be discussed in the introduction section, followed by the three main categories regarding to the different types of tantalum-based semiconductors. In each category, synthetic methodologies, influencing factors on the photocatalytic activities, strategies to enhance the efficiencies of photocatalysts and morphology control of tantalum-based materials will be discussed in detail. Future directions to further explore the research area of tantalum-based semiconductors for solar water splitting are also discussed.

  4. A Method to Analyze and Optimize the Load Sharing of Split Path Transmissions

    NASA Technical Reports Server (NTRS)

    Krantz, Timothy L.

    1996-01-01

    Split-path transmissions are promising alternatives to the common planetary transmissions for rotorcraft. Heretofore, split-path designs proposed for or used in rotorcraft have featured load-sharing devices that add undesirable weight and complexity to the designs. A method was developed to analyze and optimize the load sharing in split-path transmissions without load-sharing devices. The method uses the clocking angle as a design parameter to optimize for equal load sharing. In addition, the clocking angle tolerance necessary to maintain acceptable load sharing can be calculated. The method evaluates the effects of gear-shaft twisting and bending, tooth bending, Hertzian deformations within bearings, and movement of bearing supports on load sharing. It was used to study the NASA split-path test gearbox and the U.S. Army's Comanche helicopter main rotor gearbox. Acceptable load sharing was found to be achievable and maintainable by using proven manufacturing processes. The analytical results compare favorably to available experimental data.

  5. Split-plot microarray experiments: issues of design, power and sample size.

    PubMed

    Tsai, Pi-Wen; Lee, Mei-Ling Ting

    2005-01-01

    This article focuses on microarray experiments with two or more factors in which treatment combinations of the factors corresponding to the samples paired together onto arrays are not completely random. A main effect of one (or more) factor(s) is confounded with arrays (the experimental blocks). This is called a split-plot microarray experiment. We utilise an analysis of variance (ANOVA) model to assess differentially expressed genes for between-array and within-array comparisons that are generic under a split-plot microarray experiment. Instead of standard t- or F-test statistics that rely on mean square errors of the ANOVA model, we use a robust method, referred to as 'a pooled percentile estimator', to identify genes that are differentially expressed across different treatment conditions. We illustrate the design and analysis of split-plot microarray experiments based on a case application described by Jin et al. A brief discussion of power and sample size for split-plot microarray experiments is also presented.

  6. Dental occlusion in a split Amazon indigenous population: genetics prevails over environment.

    PubMed

    Normando, David; Faber, Jorge; Guerreiro, João Farias; Quintão, Cátia Cardoso Abdo

    2011-01-01

    Studies examining human and nonhuman primates have supported the hypothesis that the recent increase in the occurrence of misalignment of teeth and/or incorrect relation of dental arches, named dental malocclusion, is mainly attributed to the availability of a more processed diet and the reduced need for powerful masticatory action. For the first time on live human populations, genetic and tooth wear influences on occlusal variation were examined in a split indigenous population. The Arara-Iriri people are descendants of a single couple expelled from a larger village. In the resultant village, expansion occurred through the mating of close relatives, resulting in marked genetic cohesion with substantial genetic differences. Dental malocclusion, tooth wear and inbreeding coefficient were evaluated. The sample examined was composed of 176 individuals from both villages. Prevalence Ratio and descriptive differences in the outcomes frequency for each developmental stage of the dentition were considered. Statistical differences between the villages were examined using the chi-square test or Fisher's exact statistic. Tooth wear and the inbreeding coefficient (F) between the villages was tested with Mann-Whitney statistics. All the statistics were performed using two-tailed distribution at p≤0.05. The coefficient inbreeding (F) confirmed the frequent incestuous unions among the Arara-Iriri indigenous group. Despite the tooth wear similarities, we found a striking difference in occlusal patterns between the two Arara villages. In the original village, dental malocclusion was present in about one third of the population; whilst in the resultant village, the occurrence was almost doubled. Furthermore, the morphological characteristics of malocclusion were strongly different between the groups. Our findings downplay the widespread influence of tooth wear, a direct evidence of what an individual ate in the past, on occlusal variation of living human populations. They also suggest that genetics plays the most important role on dental malocclusion etiology. © 2011 Normando et al.

  7. Influence of surrounding structures upon the aerodynamic and acoustic performance of the outdoor unit of a split air-conditioner

    NASA Astrophysics Data System (ADS)

    Wu, Chengjun; Liu, Jiang; Pan, Jie

    2014-07-01

    DC-inverter split air-conditioner is widely used in Chinese homes as a result of its high-efficiency and energy-saving. Recently, the researches on its outdoor unit have focused on the influence of surrounding structures upon the aerodynamic and acoustic performance, however they are only limited to the influence of a few parameters on the performance, and practical design of the unit requires more detailed parametric analysis. Three-dimensional computational fluid dynamics(CFD) and computational aerodynamic acoustics(CAA) simulation based on FLUENT solver is used to study the influence of surrounding structures upon the aforementioned properties of the unit. The flow rate and sound pressure level are predicted for different rotating speed, and agree well with the experimental results. The parametric influence of three main surrounding structures(i.e. the heat sink, the bell-mouth type shroud and the outlet grille) upon the aerodynamic performance of the unit is analyzed thoroughly. The results demonstrate that the tip vortex plays a major role in the flow fields near the blade tip and has a great effect on the flow field of the unit. The inlet ring's size and throat's depth of the bell-mouth type shroud, and the through-flow area and configuration of upwind and downwind sections of the outlet grille are the most important factors that affect the aerodynamic performance of the unit. Furthermore, two improved schemes against the existing prototype of the unit are developed, which both can significantly increase the flow rate more than 6 %(i.e. 100 m3·h-1) at given rotating speeds. The inevitable increase of flow noise level when flow rate is increased and the advantage of keeping a lower rotating speed are also discussed. The presented work could be a useful guideline in designing the aerodynamic and acoustic performance of the split air-conditioner in engineering practice.

  8. Randomized Clinical Trial of the Innovative Bilayered Wound Dressing Made of Silk and Gelatin: Safety and Efficacy Tests Using a Split-Thickness Skin Graft Model

    PubMed Central

    Hasatsri, Sukhontha; Angspatt, Apichai

    2015-01-01

    We developed the novel silk fibroin-based bilayered wound dressing for the treatment of partial thickness wounds. And it showed relevant characteristics and accelerated the healing of full-thickness wounds in a rat model. This study is the clinical evaluation of the bilayered wound dressing to confirm its safety and efficacy for the treatment of split-thickness skin donor sites. The safety test was performed using a patch model and no evidence of marked and severe cutaneous reactions was found. The efficacy test of the bilayered wound dressing was conducted on 23 patients with 30 split-thickness skin graft donor sites to evaluate healing time, pain score, skin barrier function, and systemic reaction in comparison to Bactigras. We found that the healing time of donor site wounds treated with the bilayered wound dressing (11 ± 6 days) was significantly faster than those treated with Bactigras (14 ± 6 days) (p = 10−6). The wound sites treated with the bilayered wound dressing showed significantly less pain and more rapid skin functional barrier recovery than those treated with Bactigras (p = 10−5). Therefore, these results confirmed the clinical safety and efficacy of the bilayered wound dressing for the treatment of split-thickness skin graft donor sites. PMID:26221170

  9. Testing filamentary composites

    NASA Technical Reports Server (NTRS)

    Dow, N. F.; Rosen, B. W.

    1970-01-01

    NOL ring split-dee tensile test has the advantages that the specimen is readily fabricated by winding and the test is performed in a conventional testing machine without special fixtures. Strain gages cannot be mounted, however, and substantial bending moments are introduced.

  10. Responses of soybean to ammonium and nitrate supplied in combination to the whole root system or separately in a split-root system

    NASA Technical Reports Server (NTRS)

    Chaillou, S.; Rideout, J. W.; Raper, C. D. Jr; Raper CD, J. r. (Principal Investigator)

    1994-01-01

    To address the questions of whether allocation of carbohydrates to roots is influenced by ionic form of nitrogen absorbed and whether allocation of carbohydrates to roots in turn influences proportionality between NH4+ and NO3- uptake from mixed sources, NH4+ and NO3- were supplied separately to halves of a split-root hydroponic system and were supplied in combination to a whole-root system. Dry matter accumulation in the split-root system was 18% less in the NH4(+)-fed axis than in the NO3(-)-fed axis. This, however, does not indicate that partitioning of carbohydrate between the two axes was different. Most of the reduction in dry matter accumulation in the NH4(+)-fed axis can be accounted for by the retransport of CH2O equivalents from the root back to the shoot with amino acids produced by NH4+ assimilation. Uptake of NH4+ or NO3- by the respective halves of the split-root system was proportional to the estimated allocation of carbohydrate to that half. When NH4+ and NO3- were supplied to separate halves of the split-root system, the cumulative NH4+ to NO3- uptake ratio was 0.81. When supplied in combination to the whole-root system, the cumulative NH4+ to NO3- uptake ratio was 1.67. Thus, while the shoot may affect total nitrogen uptake through the export of carbohydrates to roots, the shoot (common for halves of the split-root system) apparently does not exert a direct effect on proportionality of NH4+ and NO3- uptake by roots. For whole roots supplied with both NH4+ and NO3-, the restriction in uptake of NO3- may involve a stimulation of NO3- efflux rather than an inhibition of NO3- influx. While only the net uptake of NH4+ and NO3- was measured by ion chromatography, monitoring at approximately hourly intervals during the first 3 days of treatment revealed irregularly occurring intervals of both depletion (net influx) and enrichment (net efflux) in solutions. In the case of NH4+, numbers of net efflux events were similar (21 to 24 out of 65 sequential sampling intervals) whether NH4+ was supplied with NO3- to whole-root systems or separately to an axis of the split-root system. In the case of NO3-, however, the number of net efflux events increased from 8 when NO3- was supplied to a separate axis of the split-root system to between 19 and 24 when NO3- was supplied with NH4+ to whole-root systems.

  11. Atmospheric Probe Model: Construction and Wind Tunnel Tests

    NASA Technical Reports Server (NTRS)

    Vogel, Jerald M.

    1998-01-01

    The material contained in this document represents a summary of the results of a low speed wind tunnel test program to determine the performance of an atmospheric probe at low speed. The probe configuration tested consists of a 2/3 scale model constructed from a combination of hard maple wood and aluminum stock. The model design includes approximately 130 surface static pressure taps. Additional hardware incorporated in the baseline model provides a mechanism for simulating external and internal trailing edge split flaps for probe flow control. Test matrix parameters include probe side slip angle, external/internal split flap deflection angle, and trip strip applications. Test output database includes surface pressure distributions on both inner and outer annular wings and probe center line velocity distributions from forward probe to aft probe locations.

  12. Effects of aggregate grading on the properties of steel fibre-reinforced concrete

    NASA Astrophysics Data System (ADS)

    Acikgens Ulas, M.; Alyamac, K. E.; Ulucan, Z. C.

    2017-09-01

    This study investigates the effects of changing the aggregate grading and maximum aggregate size (D max ) on the workability and mechanical properties of steel fibre-reinforced concrete (SFRC). Four different gradations and two different D max were used to produce SFRC mixtures with constant cement dosages and water/cement ratios. Twelve different concrete series were tested. To observe the properties of fresh concrete, slump and Ve-Be tests were performed immediately after the mixing process to investigate the effects of time on workability. The hardened properties, such as the compressive, splitting tensile and flexural strengths, were also evaluated. In addition, the toughness of the SFRC was calculated. Based on our test results, we can conclude that the grading of the aggregate and the D max have remarkable effects on the properties of fresh and hardened SFRC. In addition, the toughness of the SFRC was influenced by changing the grading of the aggregate and the D max .

  13. Internal and external scope in willingness-to-pay estimates for threatened and endangered wildlife

    USGS Publications Warehouse

    Giraud, K.L.; Loomis, J.B.; Johnson, R.L.

    1999-01-01

    Economic theory suggests willingness-to-pay (WTP) should be significantly higher for a comprehensive good than for a subset of that good. We tested this using both a split sample design (external scope test) and paired responses (internal scope test) for WTP for several endangered fish and wildlife species in the US. In the paired response case we corrected for correlation of willingness-to-pay responses using a bivariate probit model. Surprisingly, the independent split samples passed the scope test but the paired samples did not. As the results contradict each other, questions of validity for policy implications are raised. However, using either approach, the benefit of maintaining critical habitat for these species exceeds the costs.

  14. Accurate reaction-diffusion operator splitting on tetrahedral meshes for parallel stochastic molecular simulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hepburn, I.; De Schutter, E., E-mail: erik@oist.jp; Theoretical Neurobiology & Neuroengineering, University of Antwerp, Antwerp 2610

    Spatial stochastic molecular simulations in biology are limited by the intense computation required to track molecules in space either in a discrete time or discrete space framework, which has led to the development of parallel methods that can take advantage of the power of modern supercomputers in recent years. We systematically test suggested components of stochastic reaction-diffusion operator splitting in the literature and discuss their effects on accuracy. We introduce an operator splitting implementation for irregular meshes that enhances accuracy with minimal performance cost. We test a range of models in small-scale MPI simulations from simple diffusion models to realisticmore » biological models and find that multi-dimensional geometry partitioning is an important consideration for optimum performance. We demonstrate performance gains of 1-3 orders of magnitude in the parallel implementation, with peak performance strongly dependent on model specification.« less

  15. Modelling and investigation of partial wetting surfaces for drop dynamics using lattice Boltzmann method

    NASA Astrophysics Data System (ADS)

    Pravinraj, T.; Patrikar, Rajendra

    2017-07-01

    Partial wetting surfaces and its influence on the droplet movement of micro and nano scale being contemplated for many useful applications. The dynamics of the droplet usually analyzed with a multiphase lattice Boltzmann method (LBM). In this paper, the influence of partial wetting surface on the dynamics of droplet is systematically analyzed for various cases. Splitting of droplets due to chemical gradient of the surface is studied and analyses of splitting time for various widths of the strips for different Weber numbers are computed. With the proposed model one can tune the splitting volume and time by carefully choosing a strip width and droplet position. The droplet spreading on chemically heterogeneous surfaces shows that the spreading can be controlled not only by parameters of Weber number but also by tuning strip width ratio. The transportation of the droplet from hydrophobic surface to hydrophilic surface due to chemical gradient is simulated and analyzed using our hybrid thermodynamic-image processing technique. The results prove that with the progress of time the surface free energy decreases with increase in spreading area. Finally, the transportation of a droplet on microstructure gradient is demonstrated. The model explains the temporal behaviour of droplet during the spreading, recoiling and translation along with tracking of contact angle hysteresis phenomenon.

  16. An Astrobiological View on Sustainable Life

    NASA Astrophysics Data System (ADS)

    Naganuma, Takeshi

    2009-10-01

    Life on a global biosphere basis is substantiated in the form of organics and organisms, and defined as the intermediate forms (briefly expressed as CH2O) hovering between the reduced (CH4, methane) and (CO2, carbon dioxide) ends, different from the classical definition of life as a complex organization maintaining ordered structure and information. Both definitions consider sustenance of life meant as protection of life against chaos through an input of external energy. The CH2O-life connection is maintained as long as the supply of H and O lasts, which is in turn are provided by the splitting of the water molecule H2O. Water is split by electricity, as well-known from school-level experiments, and by solar radiation and geothermal heat on a global scale. In other words, the Sun's radiation and the Earth's heat as well as radioactivity split water to supply H and O for continued existence of life on the Earth. These photochemical, radiochemical and geothermal processes have influences on the evolution and current composition of the Earth's atmosphere, compared with those of Venus and Mars, and influences on the planetary climatology. This view of life may be applicable to the "search-for-life in space" and to sustainability assessment of astrobiological habitats.

  17. Demonstration of Hazardous Hypervelocity Test Capability

    NASA Technical Reports Server (NTRS)

    Rodriquez, Karen M.

    1991-01-01

    NASA Johnson Space Center (JSC) White Sands Test Facility (WSTF) participated in a joint test program with NASA JSC Hypervelocity Impact Research Laboratory (HIRL) to determine if JSC was capable of performing hypervelocity impact tests on hazardous targets. Seven pressurized vessels were evaluated under hypervelocity impact conditions. The vessels were tested with various combinations of liquids and gasses at various pressures. Results from the evaluation showed that vessels containing 100-percent pressurized gas sustained more severe damage and had a higher potential for damaging nearby equipment, than vessels containing 75-percent liquid, 25-percent inert pressurized gas. Two water-filled test vessels, one of which was placed behind an aluminum shield, failed by bulging and splitting open at the impact point; pressure was relieved without the vessel fragmenting or sustaining internal damage. An additional water-filled test vessel, placed a greater distance behind an aluminum shield, sustained damage that resembled a shotgun blast, but did not bulge or split open; again, pressure was relieved without the vessel fragmenting. Two test vessels containing volatile liquids (nitro methane and hydrazine) also failed by bulging and splitting open; neither liquid detonated under hypervelocity test conditions. A test vessel containing nitrogen gas failed by relieving pressure through a circular entry hole; multiple small penetrations opposite the point of entry provided high velocity target debris to surrounding objects. A high-pressure oxygen test vessel fragmented upon impact; the ensuing fire and high velocity fragments caused secondary damage to surrounding objects. The results from the evaluation of the pressurized vessels indicated that JSC is capable of performing hypervelocity impact tests on hazardous targets.

  18. The Effect of Sequential Dependence on the Sampling Distributions of KR-20, KR-21, and Split-Halves Reliabilities.

    ERIC Educational Resources Information Center

    Sullins, Walter L.

    Five-hundred dichotomously scored response patterns were generated with sequentially independent (SI) items and 500 with dependent (SD) items for each of thirty-six combinations of sampling parameters (i.e., three test lengths, three sample sizes, and four item difficulty distributions). KR-20, KR-21, and Split-Half (S-H) reliabilities were…

  19. Analysis of operator splitting errors for near-limit flame simulations

    NASA Astrophysics Data System (ADS)

    Lu, Zhen; Zhou, Hua; Li, Shan; Ren, Zhuyin; Lu, Tianfeng; Law, Chung K.

    2017-04-01

    High-fidelity simulations of ignition, extinction and oscillatory combustion processes are of practical interest in a broad range of combustion applications. Splitting schemes, widely employed in reactive flow simulations, could fail for stiff reaction-diffusion systems exhibiting near-limit flame phenomena. The present work first employs a model perfectly stirred reactor (PSR) problem with an Arrhenius reaction term and a linear mixing term to study the effects of splitting errors on the near-limit combustion phenomena. Analysis shows that the errors induced by decoupling of the fractional steps may result in unphysical extinction or ignition. The analysis is then extended to the prediction of ignition, extinction and oscillatory combustion in unsteady PSRs of various fuel/air mixtures with a 9-species detailed mechanism for hydrogen oxidation and an 88-species skeletal mechanism for n-heptane oxidation, together with a Jacobian-based analysis for the time scales. The tested schemes include the Strang splitting, the balanced splitting, and a newly developed semi-implicit midpoint method. Results show that the semi-implicit midpoint method can accurately reproduce the dynamics of the near-limit flame phenomena and it is second-order accurate over a wide range of time step size. For the extinction and ignition processes, both the balanced splitting and midpoint method can yield accurate predictions, whereas the Strang splitting can lead to significant shifts on the ignition/extinction processes or even unphysical results. With an enriched H radical source in the inflow stream, a delay of the ignition process and the deviation on the equilibrium temperature are observed for the Strang splitting. On the contrary, the midpoint method that solves reaction and diffusion together matches the fully implicit accurate solution. The balanced splitting predicts the temperature rise correctly but with an over-predicted peak. For the sustainable and decaying oscillatory combustion from cool flames, both the Strang splitting and the midpoint method can successfully capture the dynamic behavior, whereas the balanced splitting scheme results in significant errors.

  20. Analysis of operator splitting errors for near-limit flame simulations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lu, Zhen; Zhou, Hua; Li, Shan

    High-fidelity simulations of ignition, extinction and oscillatory combustion processes are of practical interest in a broad range of combustion applications. Splitting schemes, widely employed in reactive flow simulations, could fail for stiff reaction–diffusion systems exhibiting near-limit flame phenomena. The present work first employs a model perfectly stirred reactor (PSR) problem with an Arrhenius reaction term and a linear mixing term to study the effects of splitting errors on the near-limit combustion phenomena. Analysis shows that the errors induced by decoupling of the fractional steps may result in unphysical extinction or ignition. The analysis is then extended to the prediction ofmore » ignition, extinction and oscillatory combustion in unsteady PSRs of various fuel/air mixtures with a 9-species detailed mechanism for hydrogen oxidation and an 88-species skeletal mechanism for n-heptane oxidation, together with a Jacobian-based analysis for the time scales. The tested schemes include the Strang splitting, the balanced splitting, and a newly developed semi-implicit midpoint method. Results show that the semi-implicit midpoint method can accurately reproduce the dynamics of the near-limit flame phenomena and it is second-order accurate over a wide range of time step size. For the extinction and ignition processes, both the balanced splitting and midpoint method can yield accurate predictions, whereas the Strang splitting can lead to significant shifts on the ignition/extinction processes or even unphysical results. With an enriched H radical source in the inflow stream, a delay of the ignition process and the deviation on the equilibrium temperature are observed for the Strang splitting. On the contrary, the midpoint method that solves reaction and diffusion together matches the fully implicit accurate solution. The balanced splitting predicts the temperature rise correctly but with an over-predicted peak. For the sustainable and decaying oscillatory combustion from cool flames, both the Strang splitting and the midpoint method can successfully capture the dynamic behavior, whereas the balanced splitting scheme results in significant errors.« less

  1. Dose uniformity of scored and unscored tablets: Application of the FDA Tablet Scoring Guidance for Industry.

    PubMed

    Ciavarella, Anthony; Khan, Mansoor; Gupta, Abhay; Faustino, Patrick

    2016-06-20

    This FDA laboratory study examines the impact of tablet splitting, the effect of tablet splitters, and the presence of a tablet score on the dose uniformity of two model drugs. Whole tablets were purchased from five manufacturers for amlodipine and six for gabapentin. Two splitters were used for each drug product and the gabapentin tablets were also split by hand. Whole and split amlodipine tablets were tested for content uniformity following the general chapter of the United States Pharmacopeia (USP) Uniformity of Dosage Units <905>, which is a requirement of the new FDA Guidance for Industry on tablet scoring. The USP weight variation method was used for gabapentin split tablets based on the recommendation of the guidance. All whole tablets met the USP acceptance criteria for the Uniformity of Dosage Units. Variation in whole tablet content ranged from 0.5-2.1 standard deviation (SD) of the % label claim. Splitting the unscored amlodipine tablets resulted in a significant increase in dose variability of 6.5-25.4 SD when compared to whole tablets. Split tablets from all amlodipine drug products did not meet the USP acceptance criteria for content uniformity. Variation in the weight for gabapentin split tablets was greater than the whole tablets, ranging from 1.3-9.3 SD. All fully scored gabapentin products met the USP acceptance criteria for weight variation. Size, shape, and the presence or absence of a tablet score can affect the content uniformity and weight variation of amlodipine and gabapentin tablets. Tablet splitting produced higher variability. Differences in dose variability and fragmentation were observed between tablet splitters and hand splitting. These results are consistent with the FDA's concerns that tablet splitting "can affect how much drug is present in the split tablet and available for absorption" as stated in the guidance (1). Copyright © 2016, Parenteral Drug Association.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Three side-by-side lab houses were built, instrumented and monitored in an effort to determine through field testing and analysis the relative contributions of select technologies toward reducing energy use in new manufactured homes.The lab houses in Russellville, Alabama compared the performance of three homes built to varying levels of thermal integrity and HVAC equipment: a baseline HUD-code home equipped with an electric furnace and a split system air conditioner; an ENERGY STAR manufactured home with an enhanced thermal envelope and traditional split system heat pump; and a house designed to qualify for Zero Energy Ready Home designation with a ductlessmore » mini-split heat pump with transfer fan distribution system in place of the traditional duct system for distribution. Experiments were conducted in the lab houses to evaluate impact on energy and comfort of interior door position, window blind position and transfer fan operation. The report describes results of tracer gas and co-heating tests and presents calculation of the heat pump coefficient of performance for both the traditional heat pump and the ductless mini-split. A series of calibrated energy models was developed based on measured data and run in three locations in the Southeast to compare annual energy usage of the three homes.« less

  3. The effect of partial-span split flaps on the aerodynamic characteristics of a Clark Y wing

    NASA Technical Reports Server (NTRS)

    Wenzinger, Carl J

    1933-01-01

    Aerodynamic force tests were made in the N.A.C.A. 7 by 10 foot wind tunnel on a model Clark Y wing with a 20 percent chord split flap deflected 60 degrees downward. The tests were made to determine the effect of partial-span split flaps, located at various positions along the wing span on the aerodynamic characteristics of the wing-and-flap combination. The different lengths and locations of the flaps were obtained by cutting off portions of a full-span flap, first from the tips and then from the center. The results are given in the form of curves of lift, drag, and center of pressure. They show that with partial-span split flaps both the lift and drag are less than with full-span flaps; that the lift for a given length of flap is somewhat greater when the partial span is located at the center of the wing than when it is located at the tip portion, and that the drag for a given length of flap is the same regardless of the location over the flap with respect to the wing span.

  4. Rouleaux red blood cells splitting in microscopic thin blood smear images via local maxima, circles drawing, and mapping with original RBCs.

    PubMed

    Rehman, Amjad; Abbas, Naveed; Saba, Tanzila; Mahmood, Toqeer; Kolivand, Hoshang

    2018-04-10

    Splitting the rouleaux RBCs from single RBCs and its further subdivision is a challenging area in computer-assisted diagnosis of blood. This phenomenon is applied in complete blood count, anemia, leukemia, and malaria tests. Several automated techniques are reported in the state of art for this task but face either under or over splitting problems. The current research presents a novel approach to split Rouleaux red blood cells (chains of RBCs) precisely, which are frequently observed in the thin blood smear images. Accordingly, this research address the rouleaux splitting problem in a realistic, efficient and automated way by considering the distance transform and local maxima of the rouleaux RBCs. Rouleaux RBCs are splitted by taking their local maxima as the centres to draw circles by mid-point circle algorithm. The resulting circles are further mapped with single RBC in Rouleaux to preserve its original shape. The results of the proposed approach on standard data set are presented and analyzed statistically by achieving an average recall of 0.059, an average precision of 0.067 and F-measure 0.063 are achieved through ground truth with visual inspection. © 2018 Wiley Periodicals, Inc.

  5. Energy distribution analysis in boosted HCCI-like / LTGC engines – Understanding the trade-offs to maximize the thermal efficiency

    DOE PAGES

    Dernotte, Jeremie; Dec, John E.; Ji, Chunsheng

    2015-04-14

    A detailed understanding of the various factors affecting the trends in gross-indicated thermal efficiency with changes in key operating parameters has been carried out, applied to a one-liter displacement single-cylinder boosted Low-Temperature Gasoline Combustion (LTGC) engine. This work systematically investigates how the supplied fuel energy splits into the following four energy pathways: gross-indicated thermal efficiency, combustion inefficiency, heat transfer and exhaust losses, and how this split changes with operating conditions. Additional analysis is performed to determine the influence of variations in the ratio of specific heat capacities (γ) and the effective expansion ratio, related to the combustion-phasing retard (CA50), onmore » the energy split. Heat transfer and exhaust losses are computed using multiple standard cycle analysis techniques. Furthermore, the various methods are evaluated in order to validate the trends.« less

  6. The role of intraoperative positioning of the inferior alveolar nerve on postoperative paresthesia after bilateral sagittal split osteotomy of the mandible: prospective clinical study.

    PubMed

    Hanzelka, T; Foltán, R; Pavlíková, G; Horká, E; Sedý, J

    2011-09-01

    Bilateral sagittal split osteotomy (BSSO) aims to correct congenital or acquired mandibular abnormities. Temporary or permanent neurosensory disturbance is the most frequent complication of BSSO. To evaluate the influence of IAN handling during osteotomy, the authors undertook a prospective study in 290 patients who underwent BSSO. The occurrence and duration of paresthesia was evaluated 4 weeks, 3 months, 6 months, and 1 year after surgery. Paresthesia developed immediately after surgery in almost half of the patients. Most cases of paresthesia resolved within 1 year after surgery. A significantly higher prevalence of paresthesia was observed on the left side. The authors found a correlation between the type of IAN position between the left and right side. The type of split (and IAN exposure) did not have a significant effect on the occurrence or duration of neurosensory disturbance of the IAN. The authors did not find a correlation between the occurrence and duration of paresthesia and the direction of BSSO. Mandibular hypoplasia or mandibular progenia did not represent a predisposition for the development of paresthesia. In the development of IAN paresthesia, the type of IAN exposure and the split is less important than the side on which the split is carried out. Copyright © 2011 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  7. Survival of female northern pintails wintering in southwestern Louisiana

    USGS Publications Warehouse

    Cox, R.R.; Afton, A.D.; Pace, R. M.

    1998-01-01

    The North American breeding population of northern pintails (Anas acuta) has reached previously unprecedented low numbers 4 times since 1983. Because pintails show high fidelity to wintering areas, regional survival estimates and identification of factors influencing survival are needed to guide management of wintering pintails. We used raidiotelemetry to estimate survival rates of female pintails wintering in southwestern Lousiaina. We tested for variation in survival and hunting mortality rates in realtiaon to age (immature or adult), winter (1990-91, 1991-92, 1992-93), time period (prehunting season, first hunting season, time between split hunting seasons, second hunting season, posthunting season), body condition (body mass when released, adjusted for body size), and region (southwestern Louisiana or elsewhere on the Texas-Louisiana Gulf Coast or Mississippi Alluvial Valley).

  8. 49 CFR 40.113 - Where is other information concerning laboratories found in this regulation?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.113... specimen tests (drugs). § 40.179—Role of second laboratory in split specimen tests (adulterants). § 40.181...

  9. 49 CFR 40.113 - Where is other information concerning laboratories found in this regulation?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.113... specimen tests (drugs). § 40.179—Role of second laboratory in split specimen tests (adulterants). § 40.181...

  10. 49 CFR 40.113 - Where is other information concerning laboratories found in this regulation?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.113... specimen tests (drugs). § 40.179—Role of second laboratory in split specimen tests (adulterants). § 40.181...

  11. 49 CFR 40.113 - Where is other information concerning laboratories found in this regulation?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.113... specimen tests (drugs). § 40.179—Role of second laboratory in split specimen tests (adulterants). § 40.181...

  12. 49 CFR 40.113 - Where is other information concerning laboratories found in this regulation?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.113... specimen tests (drugs). § 40.179—Role of second laboratory in split specimen tests (adulterants). § 40.181...

  13. Stable, non-dissipative, and conservative flux-reconstruction schemes in split forms

    NASA Astrophysics Data System (ADS)

    Abe, Yoshiaki; Morinaka, Issei; Haga, Takanori; Nonomura, Taku; Shibata, Hisaichi; Miyaji, Koji

    2018-01-01

    A stable, non-dissipative, and conservative flux-reconstruction (FR) scheme is constructed and demonstrated for the compressible Euler and Navier-Stokes equations. A proposed FR framework adopts a split form (also known as the skew-symmetric form) for convective terms. Sufficient conditions to satisfy both the primary conservation (PC) and kinetic energy preservation (KEP) properties are rigorously derived by polynomial-based analysis for a general FR framework. It is found that the split form needs to be expressed in the PC split form or KEP split form to satisfy each property in discrete sense. The PC split form is retrieved from existing general forms (Kennedy and Gruber [33]); in contrast, we have newly introduced the KEP split form as a comprehensive form constituting a KEP scheme in the FR framework. Furthermore, Gauss-Lobatto (GL) solution points and g2 correction function are required to satisfy the KEP property while any correction functions are available for the PC property. The split-form FR framework to satisfy the KEP property, eventually, is similar to the split-form DGSEM-GL method proposed by Gassner [23], but which, in this study, is derived solely by polynomial-based analysis without explicitly using the diagonal-norm SBP property. Based on a series of numerical tests (e.g., Sod shock tube), both the PC and KEP properties have been verified. We have also demonstrated that using a non-dissipative KEP flux, a sixteenth-order (p15) simulation of the viscous Taylor-Green vortex (Re = 1 , 600) is stable and its results are free of unphysical oscillations on relatively coarse mesh (total number of degrees of freedom (DoFs) is 1283).

  14. Characteristics of the gait adaptation process due to split-belt treadmill walking under a wide range of right-left speed ratios in humans.

    PubMed

    Yokoyama, Hikaru; Sato, Koji; Ogawa, Tetsuya; Yamamoto, Shin-Ichiro; Nakazawa, Kimitaka; Kawashima, Noritaka

    2018-01-01

    The adaptability of human bipedal locomotion has been studied using split-belt treadmill walking. Most of previous studies utilized experimental protocol under remarkably different split ratios (e.g. 1:2, 1:3, or 1:4). While, there is limited research with regard to adaptive process under the small speed ratios. It is important to know the nature of adaptive process under ratio smaller than 1:2, because systematic evaluation of the gait adaptation under small to moderate split ratios would enable us to examine relative contribution of two forms of adaptation (reactive feedback and predictive feedforward control) on gait adaptation. We therefore examined a gait behavior due to on split-belt treadmill adaptation under five belt speed difference conditions (from 1:1.2 to 1:2). Gait parameters related to reactive control (stance time) showed quick adjustments immediately after imposing the split-belt walking in all five speed ratios. Meanwhile, parameters related to predictive control (step length and anterior force) showed a clear pattern of adaptation and subsequent aftereffects except for the 1:1.2 adaptation. Additionally, the 1:1.2 ratio was distinguished from other ratios by cluster analysis based on the relationship between the size of adaptation and the aftereffect. Our findings indicate that the reactive feedback control was involved in all the speed ratios tested and that the extent of reaction was proportionally dependent on the speed ratio of the split-belt. On the contrary, predictive feedforward control was necessary when the ratio of the split-belt was greater. These results enable us to consider how a given split-belt training condition would affect the relative contribution of the two strategies on gait adaptation, which must be considered when developing rehabilitation interventions for stroke patients.

  15. The gj factor of a bound electron and the hyperfine structure splitting in hydrogenlike ions

    NASA Astrophysics Data System (ADS)

    Beier, Thomas

    2000-12-01

    The comparison between theory and experiment of the hyperfine structure splitting and the electronic gj factor in heavy highly charged ions provides a unique testing ground for quantum electrodynamics in the presence of strong electric and magnetic fields. A theoretical evaluation is presented of all quantum electrodynamical contributions to the ground-state hfs splitting in hydrogenlike and lithiumlike atoms as well as to the gj factor. Binding and nuclear effects are discussed as well. A comparison with the available experimental data is performed, and a detailed discussion of theoretical sources of uncertainty is included which is mainly due to insufficiently known nuclear properties.

  16. Split-cross-bridge resistor for testing for proper fabrication of integrated circuits

    NASA Technical Reports Server (NTRS)

    Buehler, M. G. (Inventor)

    1985-01-01

    An electrical testing structure and method is described whereby a test structure is fabricated on a large scale integrated circuit wafer along with the circuit components and has a van der Pauw cross resistor in conjunction with a bridge resistor and a split bridge resistor, the latter having two channels each a line width wide, corresponding to the line width of the wafer circuit components, and with the two channels separated by a space equal to the line spacing of the wafer circuit components. The testing structure has associated voltage and current contact pads arranged in a two by four array for conveniently passing currents through the test structure and measuring voltages at appropriate points to calculate the sheet resistance, line width, line spacing, and line pitch of the circuit components on the wafer electrically.

  17. Investigation in the Langley 19-foot Pressure Tunnel of Two Wings of NACA 65-210 and 64-210 Airfoil Sections with Various Type Flaps

    NASA Technical Reports Server (NTRS)

    Sivells, James C; Spooner, Stanley H

    1949-01-01

    Report presents the results of an investigation conducted in the Langley 19-foot pressure tunnel to determine the maximum lift and stalling characteristics of two thin wings equipped with several types of flaps. Split, single slotted, and double slotted flaps were tested on one wing which had NACA 65-210 airfoil sections and split and double slotted flaps were tested on the other, which had NACA 64-210 airfoil sections. Both wings were zero sweep, an aspect ratio of 9, and a taper ratio of 0.4.

  18. Crack resistance determination of material by wedge splitting a chevron-notched specimen

    NASA Astrophysics Data System (ADS)

    Deryugin, Ye. Ye.

    2017-12-01

    An original method is proposed for the crack resistance determination of a material by wedge splitting of a chevron-notched specimen. It was developed at the Institute of Strength Physics and Materials Science SB RAS in the laboratory of Physical Mesomechanics and Nondestructive Methods of Control. An example of the crack resistance test of technical titanium VT1-0 is considered.

  19. Factor levels for density comparisons in the split-block spacing design

    Treesearch

    Kurt H. Riitters; Brian J. Stanton; Robbert H. Walkup

    1989-01-01

    The split-block spacing design is a compact test of the effects of within-row and between-row spacings. But the sometimes awkward analysis of density (i.e., trees/ha) effects may deter use of the design. The analysis is simpler if the row spacings are chosen to obtain a balanced set of equally spaced density and rectangularity treatments. A spacing study in poplar (...

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Simbeck, D.J.

    Clinch River - Environmental Restoration Program (CR-ERP) personnel and Tennessee Valley Authority (TVA) personnel conducted a study during the week of October 21-28, 1993, as described in the Statement of Work (SOW) document. The organisms specified for testing were larval fathead minnows, Pimephales promelas, and the daphnid, Ceriodaphnia dubia. Due to serious reproduction/embryo abortion problems with the TVA daphnid cultures, TVA conducted tests during this study period using only fathead minnows. A split sample test using daphnids only will be scheduled during 1994 as a substitute for this study period. Surface water samples were collected by TVA Field Engineering personnelmore » from Poplar Creek Mile 2.9, Mile 4.3, and Mile 5.1 on October 20, 22, and 25. Samples were split and provided to the CR-ERP and TVA toxicology laboratories for testing. Exposure of test organisms to these samples resulted in no toxicity (survival or growth) in testing conducted by TVA.« less

  1. Development of helicopter transmission seals, task 2

    NASA Technical Reports Server (NTRS)

    Hayden, T. S.; Keller, C. H., Jr.

    1973-01-01

    High speed helicopter transmission seal concepts were designed, fabricated and tested. The concepts were a dual element split ring seal and a circumferential seal. The tests were performed in a rig using an actual input quill assembly. The test conditions were selected to simulate transmission operation and were 230 F oil temperature, and a sliding speed of 9400 ft/min. The split ring seal exhibited gross leakage and was considered unsatisfactory, while the circumferential seal leakage was less than 1 c.c./hour; this leakage is within acceptable limits. The circumferential seal wear was only to .0005 inches during a 100 hour run (40 starts and stops). During a 40 hour contamination test (mesh silica flour) the seal total wear was a maximum of .004 inches. This wear is considered acceptable.

  2. Comparative experimental study of dynamic compressive strength of mortar with glass and basalt fibres

    NASA Astrophysics Data System (ADS)

    Kruszka, Leopold; Moćko, Wojciech; Fenu, Luigi; Cadoni, Ezio

    2015-09-01

    Specimen reinforced with glass and basalt fibers were prepared using Standard Portland cement (CEM I, 52.5 R as prescribed by EN 197-1) and standard sand, in accordance with EN 196-1. From this cementitious mixture, a reference cement mortar without fibers was first prepared. Compressive strength, modulus of elasticity, and mod of fracture were determined for all specimens. Static and dynamic properties were investigated using Instron testing machine and split Hopkinson pressure bar, respectively. Content of the glass fibers in the mortar does not influence the fracture stress at static loading conditions in a clearly observed way. Moreover at dynamic range 5% content of the fiber results in a significant drop of fracture stress. Analysis of the basalt fibers influence on the fracture stress shows that optimal content of this reinforcement is equal to 3% for both static and dynamic loading conditions. Further increase of the fiber share gives the opposite effect, i.e. drop of the fracture stress.

  3. A novel theoretical probe of the SrTiO3 surface under water-splitting conditions

    NASA Astrophysics Data System (ADS)

    Letchworth-Weaver, Kendra; Gunceler, Deniz; Arias, Tomás; Plaza, Manuel; Huang, Xin; Brock, Joel; Rodriguez-López, Joaquin; Abruña, Hector

    2014-03-01

    Understanding the reaction mechanisms required to generate hydrogen fuel by photoelectrolysis of water is essential to energy conversion research. These reaction pathways are strongly influenced by the geometry and electronic structure of the electrode surface under water-splitting conditions. Electrochemical microscopy has demonstrated that biasing a SrTiO3 (001) surface can lead to an increase in water-splitting activity. In operando X-ray reflectivity measurements at the Cornell High Energy Synchrotron Source (CHESS) correlate this increase in activity to a significant reorganization in the surface structure but are unable to determine the exact nature of this change. Joint Density-Functional Theory (JDFT), a rigorous yet computationally efficient alternative to molecular dynamics, provides a quantum-mechanical description of an electrode surface in contact with an aqueous environment, and a microscopically detailed description of the interfacial liquid structure. Our JDFT calculations determine the structure of the activated SrTiO3 surface and explore why it is correlated with higher activity for water splitting. With no empirical parameters whatsoever, we predict the X-ray crystal truncation rods for SrTiO3, finding excellent agreement with experiment. Funded by the Energy Materials Center at Cornell (EMC2).

  4. Development of classification models for identifying "true" P-glycoprotein (P-gp) inhibitors through inhibition, ATPase activation and monolayer efflux assays.

    PubMed

    Rapposelli, Simona; Coi, Alessio; Imbriani, Marcello; Bianucci, Anna Maria

    2012-01-01

    P-glycoprotein (P-gp) is an efflux pump involved in the protection of tissues of several organs by influencing xenobiotic disposition. P-gp plays a key role in multidrug resistance and in the progression of many neurodegenerative diseases. The development of new and more effective therapeutics targeting P-gp thus represents an intriguing challenge in drug discovery. P-gp inhibition may be considered as a valid approach to improve drug bioavailability as well as to overcome drug resistance to many kinds of tumours characterized by the over-expression of this protein. This study aims to develop classification models from a unique dataset of 59 compounds for which there were homogeneous experimental data on P-gp inhibition, ATPase activation and monolayer efflux. For each experiment, the dataset was split into a training and a test set comprising 39 and 20 molecules, respectively. Rational splitting was accomplished using a sphere-exclusion type algorithm. After a two-step (internal/external) validation, the best-performing classification models were used in a consensus predicting task for the identification of compounds named as "true" P-gp inhibitors, i.e., molecules able to inhibit P-gp without being effluxed by P-gp itself and simultaneously unable to activate the ATPase function.

  5. Enhancement of intrinsic optical signal recording with split spectrum optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Thapa, Damber; Wang, Benquan; Lu, Yiming; Son, Taeyoon; Yao, Xincheng

    2017-09-01

    Functional optical coherence tomography (OCT) of stimulus-evoked intrinsic optical signal (IOS) promises to be a new methodology for high-resolution mapping of retinal neural dysfunctions. However, its practical applications for non-invasive examination of retinal function have been hindered by the low signal-to-noise ratio (SNR) and small magnitude of IOSs. Split spectrum amplitude-decorrelation has been demonstrated to improve the image quality of OCT angiography. In this study, we exploited split spectrum strategy to improve the sensitivity of IOS recording. The full OCT spectrum was split into multiple spectral bands and IOSs from each sub-band were calculated separately and then combined to generate a single IOS image sequence. The algorithm was tested on in vivo images of frog retinas. It significantly improved both IOS magnitude and SNR, which are essential for practical applications of functional IOS imaging.

  6. Activation of response force by self-splitting objects: where are the limits of feedforward Gestalt processing?

    PubMed

    Schmidt, Filipp; Weber, Andreas; Schmidt, Thomas

    2014-08-21

    Most objects can be recognized easily even when they are partly occluded. This also holds when several overlapping objects share the same surface features (self-splitting objects) which is an illustration of the grouping principle of Good Gestalt. We employed outline and filled contour stimuli in a primed flanker task to test whether the processing of self-splitting objects is in accordance with a simple feedforward model. We obtained priming effects in response time and response force for both types of stimuli, even when increasing the number of occluders up to three. The results for outline contours were in full accordance with a feedforward account. This was not the case for the results for filled contours (i.e., for self-splitting objects), especially under conditions of strong occlusion. We conclude that the implementation of the Good Gestalt principle is fast but still based on recurrent processing. © 2014 ARVO.

  7. A dimensionally split Cartesian cut cell method for hyperbolic conservation laws

    NASA Astrophysics Data System (ADS)

    Gokhale, Nandan; Nikiforakis, Nikos; Klein, Rupert

    2018-07-01

    We present a dimensionally split method for solving hyperbolic conservation laws on Cartesian cut cell meshes. The approach combines local geometric and wave speed information to determine a novel stabilised cut cell flux, and we provide a full description of its three-dimensional implementation in the dimensionally split framework of Klein et al. [1]. The convergence and stability of the method are proved for the one-dimensional linear advection equation, while its multi-dimensional numerical performance is investigated through the computation of solutions to a number of test problems for the linear advection and Euler equations. When compared to the cut cell flux of Klein et al., it was found that the new flux alleviates the problem of oscillatory boundary solutions produced by the former at higher Courant numbers, and also enables the computation of more accurate solutions near stagnation points. Being dimensionally split, the method is simple to implement and extends readily to multiple dimensions.

  8. Tablet splitting and weight uniformity of half-tablets of 4 medications in pharmacy practice.

    PubMed

    Tahaineh, Linda M; Gharaibeh, Shadi F

    2012-08-01

    Tablet splitting is a common practice for multiple reasons including cost savings; however, it does not necessarily result in weight-uniform half-tablets. To determine weight uniformity of half-tablets resulting from splitting 4 products available in the Jordanian market and investigate the effect of tablet characteristics on weight uniformity of half-tablets. Ten random tablets each of warfarin 5 mg, digoxin 0.25 mg, phenobarbital 30 mg, and prednisolone 5 mg were weighed and split by 6 PharmD students using a knife. The resulting half-tablets were weighed and evaluated for weight uniformity. Other relevant physical characteristics of the 4 products were measured. The average tablet hardness of the sampled tablets ranged from 40.3 N to 68.9 N. Digoxin, phenobarbital, and prednisolone half-tablets failed the weight uniformity test; however, warfarin half-tablets passed. Digoxin, warfarin, and phenobarbital tablets had a score line and warfarin tablets had the deepest score line of 0.81 mm. Splitting warfarin tablets produces weight-uniform half-tablets that may possibly be attributed to the hardness and the presence of a deep score line. Digoxin, phenobarbital, and prednisolone tablet splitting produces highly weight variable half-tablets. This can be of clinical significance in the case of the narrow therapeutic index medication digoxin.

  9. Multi-dimensional Upwind Fluctuation Splitting Scheme with Mesh Adaption for Hypersonic Viscous Flow. Degree awarded by Virginia Polytechnic Inst. and State Univ., 9 Nov. 2001

    NASA Technical Reports Server (NTRS)

    Wood, William A., III

    2002-01-01

    A multi-dimensional upwind fluctuation splitting scheme is developed and implemented for two-dimensional and axisymmetric formulations of the Navier-Stokes equations on unstructured meshes. Key features of the scheme are the compact stencil, full upwinding, and non-linear discretization which allow for second-order accuracy with enforced positivity. Throughout, the fluctuation splitting scheme is compared to a current state-of-the-art finite volume approach, a second-order, dual mesh upwind flux difference splitting scheme (DMFDSFV), and is shown to produce more accurate results using fewer computer resources for a wide range of test cases. A Blasius flat plate viscous validation case reveals a more accurate upsilon-velocity profile for fluctuation splitting, and the reduced artificial dissipation production is shown relative to DMFDSFV. Remarkably, the fluctuation splitting scheme shows grid converged skin friction coefficients with only five points in the boundary layer for this case. The second half of the report develops a local, compact, anisotropic unstructured mesh adaptation scheme in conjunction with the multi-dimensional upwind solver, exhibiting a characteristic alignment behavior for scalar problems. The adaptation strategy is extended to the two-dimensional and axisymmetric Navier-Stokes equations of motion through the concept of fluctuation minimization.

  10. Dynamic load-sharing characteristic analysis of face gear power-split gear system based on tooth contact characteristics

    NASA Astrophysics Data System (ADS)

    Dong, Hao; Hu, Yahui

    2018-04-01

    The bend-torsion coupling dynamics load-sharing model of the helicopter face gear split torque transmission system is established by using concentrated quality standard, to analyzing the dynamic load-sharing characteristic. The mathematical models include nonlinear support stiffness, time-varying meshing stiffness, damping, gear backlash. The results showed that the errors collectively influenced the load sharing characteristics, only reduce a certain error, it is never fully reached the perfect loading sharing characteristics. The system load-sharing performance can be improved through floating shaft support. The above-method will provide a theoretical basis and data support for its dynamic performance optimization design.

  11. Influence of atomic densities on propagation property for ultrashort pulses in a two-level medium

    NASA Astrophysics Data System (ADS)

    Liu, Bingxin; Gong, Shangqing; Song, Xiaohong; Jin, Shiqi

    2005-05-01

    The influence of atomic densities on the propagation property for ultrashort pulses in a two-level atom (TLA) medium is investigated. With higher atomic densities, the self-induced transparency (SIT) cannot be recovered even for 2? ultrashort pulses. New features such as pulse splitting, red-shift and blue-shift of the corresponding spectra arise, and the component of central frequency gradually disappears.

  12. Tablet splitting: is it worthwhile? Analysis of drug content and weight uniformity for half tablets of 16 commonly used medications in the outpatient setting.

    PubMed

    Helmy, Sally A

    2015-01-01

    Tablet splitting is a well-established medical practice in clinical settings for multiple reasons, including cost savings and ease of swallowing. However, it does not necessarily result in weight-uniform half tablets. To (a) investigate the effect of tablet characteristics on weight and content uniformity of half tablets, resulting from splitting 16 commonly used medications in the outpatient setting and (b) provide recommendations for safe tablet-splitting prescribing practices. Ten random tablets from each of the selected medications were weighed and split by 5 volunteers (2 men and 3 women aged 25-44 years) using a knife. The selected medications were mirtazapine 30 mg, bromazepam 3 mg, oxcarbazepin 150 mg, sertraline 50 mg, carvedilol 25 mg, bisoprolol fumarate 10 mg, losartan 50 mg, digoxin 0.25 mg, amiodarone HCl 200 mg, metformin HCl 1,000 mg, glimepiride 4 mg, montelukast 10 mg, ibuprofen 600 mg, celecoxib 200 mg, meloxicam 15 mg, and sildenafil citrate 50 mg. The resulting half tablets were evaluated for weight and drug content uniformity in accordance with proxy United States Pharmacopeia (USP) specification (95%-105% for digoxin and 90%-110% for the other 15 drugs). Weight and drug content uniformity were assessed by comparing weight or drug content of the half tablets with one-half of the mean weight or drug content for all whole tablets in the sample. The percentages by which the weight and drug content of each whole tablet or half tablet differed from sample mean values were calculated. Other relevant physical characteristics of the 16 products were measured. A total of 52 of 320 half tablets (16.2%) and 48 of 320 half tablets (15.0%) fell outside of the proxy USP specification for weight and drug content, respectively. Bromazepam, carvedilol, bisoprolol, losartan, digoxin, and meloxicam half tablets failed the weight and content uniformity test; however, the half tablets for the rest of the medications passed the test. Mean percent weight loss after splitting was less than 1.5% for all drugs. Bromazepam, carvedilol, and digoxin showed the highest powdering loss during the tablet-splitting process. Tablet splitting could be safer and easier when drug- and patient-specific criteria have been met. Tablet size, shape, and hardness may also play a role in the decision to split a tablet or not. Tablets containing drugs with a wide therapeutic index and long half-life might be more suitable candidates for division. Dose variation exceeded a proxy USP specification for more than one-third of sampled half tablets of bromazepam, carvedilol, bisoprolol, and digoxin. Drug content variation in half tablets appeared to be attributed to weight variation due to fragment or powder loss during the splitting process.

  13. Influence of a vertical subject on research in biomedicine and activities of The Cochrane Collaboration branch on medical students' knowledge and attitudes toward evidence-based medicine

    PubMed Central

    Balajić, Karolina; Barac-Latas, Vesna; Drenjančević, Ines; Ostojić, Marko; Fabijanić, Damir; Puljak, Livia

    2012-01-01

    Aim To investigate whether the introduction of a vertical subject on research in biomedicine and founding of The Cochrane Collaboration branch at the University of Split School of Medicine influenced students’ knowledge and attitudes toward evidence-based medicine (EBM), including the use of research literature. Methods We used a 26-item questionnaire on EBM knowledge and attitudes to survey 1232 medical students of all study years in 3 medical schools in Croatia (Split, Rijeka, Osijek) and the Croatian-speaking medical school in Mostar (Bosnia and Herzegovina). Results Students from the University of Split School of Medicine who had been exposed to the vertical subject on research in biomedicine and activities of The Cochrane Collaboration at the school had better knowledge and more positive attitudes toward EBM. In general, students rarely searched for evidence; 28% of students searched for evidence more than once a month and 96% of students used only textbooks in Croatian and teachers’ handouts, even though 74% of students agreed that articles from scholarly journals were an important supplement for textbooks. Conclusion Building up an environment that fosters EBM may be beneficial for students’ knowledge and attitudes toward EBM. Teachers should encourage and require using evidence during all the courses in medical school. PMID:22911530

  14. Advanced Rotorcraft Transmission (ART) program status

    NASA Technical Reports Server (NTRS)

    Bossler, Robert; Heath, Gregory

    1991-01-01

    Reported herein is work done on the Advanced Rotorcraft Transmission by McDonnell Douglas Helicopter Company under Army/NASA contract. The novel concept pursued includes the use of face gears for power transmission and a torque splitting arrangement. The design reduces the size and weight of the corner-turning hardware and the next reduction stage. New methods of analyzing face gears have increased confidence in their usefulness. Test gears have been designed and manufactured for power transmission testing on the NASA-Lewis spiral bevel test rig. Transmission design effort has included finite element modeling of the split torque paths to assure equal deflection under load. A finite element model of the Apache main transmission has been completed to substantiate noise prediction methods. A positive engagement overrunning clutch design is described. Test spur gears have been made by near-net-shape forging from five different materials. Three housing materials have been procured for evaluation testing.

  15. Academy Helps Army Be All that It Can Be.

    ERIC Educational Resources Information Center

    Holden, Constance

    1987-01-01

    Summarizes a report which attempted to determine the usefulness of various human potential technologies in military training programs. Includes information on sleep learning, accelerated learning, mental practice, biofeedback, group cohesion, split-brain effects, altered mental states, influence strategies, and parapsychology. (TW)

  16. C-Peptide Test

    MedlinePlus

    ... Cancer Therapy Glucose Tests Gonorrhea Testing Gram Stain Growth Hormone Haptoglobin hCG Pregnancy hCG Tumor Marker HDL Cholesterol ... splits apart and forms one molecule of C-peptide and one molecule of insulin . Insulin is the hormone that is vital for the body to use ...

  17. Shear wave splitting observations across the Juan de Fuca plate system: Ridge- to-trench constraints on mantle flow from 2 years of Cascadia Initiative OBS data

    NASA Astrophysics Data System (ADS)

    Bodmer, M.; Toomey, D. R.; Hooft, E. E. E.

    2014-12-01

    We present SKS splitting measurements for the first two years of data collected by the Cascadia Initiative (CI) amphibious array. Our analysis includes observations from over 100 ocean bottom seismometers (OBS), as well as 31 onshore stations, and spans both the Juan de Fuca and Gorda plates. The CI dataset is unique in that it includes several regions that can distinctly influence anisotropic fabric development such as: the upwelling mantle beneath the Juan de Fuca and Gorda ridges, the young evolving oceanic lithosphere of the plate interior, the Blanco transform fault, and the Cascadia subduction zone. For the first time, we are able to analyze these regions with a single dataset, and using a common methodology. Splitting measurements are routinely done on land sites, but have been completed on relatively few OBS stations. This is largely due to the low signal to noise present in OBS data, which can obscure the splitting results. To address that nearly all the OBS data exceeds the global high noise limit at the frequencies used for splitting, we implement a rigorous quality control scheme. Our method specifically takes into account the response of common splitting methods to high noise data and addresses known issues such as cycle skipping, false minima, low transverse energy, and near-null measurements. Individual measurements are filtered at 0.03-0.1 Hz, manually checked for quality, and stacked. Preliminary results show trench perpendicular onshore measurements consistent with previous studies. Oceanic measurements in the plate interior show a coherent fast axis roughly aligned with absolute plate motion. Several measurements near the ridge and trench appear to be rotated in the ridge and trench parallel directions. Continuing work will integrate splitting measurements from the final two years of the CI with these findings, which will be used to characterize the ridge-to-trench mantle flow across the Juan de Fuca plate system.

  18. Survival of resin infiltrated ceramics under influence of fatigue.

    PubMed

    Aboushelib, Moustafa N; Elsafi, Mohamed H

    2016-04-01

    to evaluate influence of cyclic fatigue on two resin infiltrated ceramics and three all-ceramic crowns manufactured using CAD/CAM technology. CAD/CAM anatomically shaped crowns were manufactured using two resin infiltrated ceramics (Lava Ultimate and Vita Enamic), two reinforced glass ceramic milling blocks ((IPS)Empress CAD and (IPS)e.max CAD) and a veneered zirconia core ((IPS)Zir CAD). (IPS)e.max CAD and (IPS)Zir CAD were milled into 0.5mm thick anatomically shaped core structure which received standardized press-on veneer ceramic. The manufactured crowns were cemented on standardized resin dies using a resin adhesive (Panavia F2.0). Initial fracture strength of half of the specimens was calculated using one cycle load to failure in a universal testing machine. The remaining crowns were subjected to 3.7 million chewing cycles (load range 50-200N at 3s interval) in a custom made pneumatic fatigue tester. Survival statistics were calculated and Weibull modulus was measured from fitted load-cycle-failure diagrams. Scanning electron microscopy was performed to fractographically analyze fractured surfaces. Data were analyzed using two way analysis of variance and Bonferroni post hoc tests (α=0.05). Dynamic fatigue resulted in significant reduction (F=7.54, P<0.005) of the initial fracture strength of the tested specimens. Zirconia showed the highest deterioration percent (34% reduction in strength) followed by (IPS)Empress (32.2%), (IPS)e.max (27.1%) while Lava Ultimate and Vita Enamic showed the lowest percent of reduction in strength. The two types of resin infiltrated ceramics and (IPS)Empress demonstrated the highest percent of fracture incidences under the influence of fatigue (35-45% splitting). None of the tested veneered zirconia restorations were fractured during testing, however, chipping of the veneer ceramics was observed in 6 crowns. The lowest percent of failure was observed for (IPS)e.max crowns manifested as 3 cases of minor chipping in addition to two complete fracture incidences. SEM images demonstrated the internal structure of the tested materials and detected location and size of the critical crack. The internal structure of the tested materials significantly influenced their fatigue behavior. Resin infiltrated ceramics were least influenced by fatigue while the characteristic strength of zirconia prevented core fracture but failure still occurred from the weaker veneer ceramic. Copyright © 2015 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  19. Does Simultaneous Third Molar Extraction Increase Intraoperative and Perioperative Complications in Orthognathic Surgery?

    PubMed

    Steinbacher, Derek M; Kontaxis, Katrina L

    2016-06-01

    Prior to orthognathic surgery, most surgeons recommend third molar extraction. Espoused reasons include potential risk for infection, untoward osteotomies, and worsened postoperative discomfort. However, in addition to being another procedure for the patient, this may necessitate a longer preorthognathic surgery phase. The purpose of this study is to compare the outcomes of orthognathic surgery with staged versus simultaneous third molar extractions. This was a retrospective analysis of patients who underwent orthognathic surgery from 2013 to 2014, with at least a 1-year follow-up period. Patients were stratified into 2 groups: Extraction of third molars at the time of surgery and prior extraction of third molars. Primary outcomes included the occurrence of unfavorable splits, infection, bleeding, malocclusion, and hardware failure. Secondary outcomes were procedure time, postoperative pain, and length of stay. Pearson χ tests and 2-tailed unpaired t tests were performed to determine if there was an association between the simultaneous removal of third molars and the primary and secondary outcome measures, respectively. One hundred patients were included in the study. Forty-nine patients had third molars extracted at the time of surgery and fifty-one did not. Complications included unfavorable split, postoperative infection, mild postoperative bleeding, postoperative malocclusion, and hardware failure. There was no significant difference in the incidence of complications in both groups. Procedure time was not considerably increased with extractions. There was no significant difference in postoperative pain or length of stay between both groups. Removing third molars concurrently with orthognathic surgery does not increase the risk of adverse outcomes, nor does it significantly influence hospital course.

  20. Better Than Nothing: A Rational Approach for Minimizing the Impact of Outflow Strategy on Cerebrovascular Simulations.

    PubMed

    Chnafa, C; Brina, O; Pereira, V M; Steinman, D A

    2018-02-01

    Computational fluid dynamics simulations of neurovascular diseases are impacted by various modeling assumptions and uncertainties, including outlet boundary conditions. Many studies of intracranial aneurysms, for example, assume zero pressure at all outlets, often the default ("do-nothing") strategy, with no physiological basis. Others divide outflow according to the outlet diameters cubed, nominally based on the more physiological Murray's law but still susceptible to subjective choices about the segmented model extent. Here we demonstrate the limitations and impact of these outflow strategies, against a novel "splitting" method introduced here. With our method, the segmented lumen is split into its constituent bifurcations, where flow divisions are estimated locally using a power law. Together these provide the global outflow rate boundary conditions. The impact of outflow strategy on flow rates was tested for 70 cases of MCA aneurysm with 0D simulations. The impact on hemodynamic indices used for rupture status assessment was tested for 10 cases with 3D simulations. Differences in flow rates among the various strategies were up to 70%, with a non-negligible impact on average and oscillatory wall shear stresses in some cases. Murray-law and splitting methods gave flow rates closest to physiological values reported in the literature; however, only the splitting method was insensitive to arbitrary truncation of the model extent. Cerebrovascular simulations can depend strongly on the outflow strategy. The default zero-pressure method should be avoided in favor of Murray-law or splitting methods, the latter being released as an open-source tool to encourage the standardization of outflow strategies. © 2018 by American Journal of Neuroradiology.

  1. Monte Carlo based modelling approach for designing and predicting cytotoxicity of 2-phenylindole derivatives against breast cancer cell line MCF7.

    PubMed

    Gaikwad, Ruchi; Ghorai, Soumajit; Amin, Sk Abdul; Adhikari, Nilanjan; Patel, Tarun; Das, Kalpataru; Jha, Tarun; Gayen, Shovanlal

    2018-06-01

    Breast cancer is one of the leading causes of cancers among the variety of cancers in woman all over the world. Compounds with phenylindole scaffold were found to execute promising cytotoxicity against breast cancer cell line MCF7. In the present study, a Monte Carlo based QSAR analysis was performed on a dataset containing 102 phenylindoles in order to accelerate the efforts to find out better cytotoxic phenylindoles against MCF7 cell line. The statistical qualities of the generated models were found to be quite good as far as the internal and external validation were concerned. The best models from each split (Split 1: R 2  = 0.6944, Q 2  = 0.6495; Split 2: R 2  = 0.8202, Q 2  = 0.7998; Split 3: R 2  = 0.8603, Q 2  = 0.8357) for the test set were selected and Y-scrambling test and applicability domain analysis were also performed to ensure the robustness of these models. Among these models, model from split 3 obtained by using hybrid descriptors (combination of SMILES and HSG with 0 ECk connectivity) was used to identify and classify the structural attributes as promoters as well as hinderers of cytotoxicity for these 2-phenylindole derivatives. Results from the analysis were further used to design and predict some probable new 2-phenylindole derivatives having promising cytotoxicity (IC 50  < 55 nM) against MCF7. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. The use of leucocyte and platelet-rich fibrin in socket management and ridge preservation: a split-mouth, randomized, controlled clinical trial.

    PubMed

    Temmerman, Andy; Vandessel, Jeroen; Castro, Ana; Jacobs, Reinhilde; Teughels, Wim; Pinto, Nelson; Quirynen, Marc

    2016-11-01

    To investigate the influence of the use L-PRF as a socket filling material and its ridge preservation properties. Twenty-two patients in need of single bilateral and closely symmetrical tooth extractions in the maxilla or mandible were included in a split-mouth RCT. Treatments were randomly assigned (L-PRF socket filling versus natural healing). CBCT scans were obtained after tooth extraction and three months. Scans were evaluated by superimposition using the original DICOM data. Mean ridge width differences between timepoints were measured at three levels below the crest on both the buccal and lingual sides (crest -1 mm (primary outcome variable), -3 mm and -5 mm). Mean vertical height changes at the buccal were -1.5 mm (±1.3) for control sites and 0.5 mm (±2.3) for test sites (p < 0.005). At the buccal side, control sites values were, respectively, -2.1 (±2.5), -0.3 mm (±0.3) (p < 0.005) and -0.1 mm (±0.0), and test sites values were, respectively, -0.6 mm (±2.2) (p < 0.005), -0.1 mm (±0.3) and 0.0 mm (±0.1). Significant differences (p < 0.005) were found for total width reduction between test (-22.84%) and control sites (-51.92%) at 1 mm below crest level. Significant differences were found for socket fill (visible mineralized bone) between test (94.7%) and control sites (63.3%). The use of L-PRF as a socket filling material to achieve preservation of horizontal and vertical ridge dimension at three  months after tooth extraction is beneficial. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Physiological behavior of bean's seeds and grains during storage.

    PubMed

    Cassol, Flávia D R; Fortes, Andréa M T; Mendonça, Lorena C; Buturi, Camila V; Marcon, Thaís R

    2016-05-31

    Beans are one of the most used foods to meet the energy needs of the Brazilian diet, requiring farmers to use high seed physiological potential. The aim was to evaluate the physiological quality of beans stored for 360 days. Analyses were performed at 0, 30, 90, 180, 270, and 360 days after receiving the seeds (S1 and S2) and grains (G1 and G2) of BRS Splendor. Tests of germination, accelerated aging, cold, speed of germination, average length of shoots, and root were performed. The experimental design was completely randomized split-plot in time and the means were compared through Tukey test at 5% probability. Seed germination was not affected in S2, while the drop in S1 and G1 was significant. The vigor of grains from field 1 declined from 91 to 50% and from 93% to 76% by accelerated aging and cold, respectively, after 360 days. The germination speed tests performed showed a decreased during the experiment. The grains from field 1 had lower physiological quality. The accelerated aging and cold tests, through the speed of germination parameter, showed decrease in the vigor of the Splendor BRS. The storage period influenced the physiological quality of the beans tested.

  4. Estimating sleep parameters using nasal pressure signals applicable to continuous positive airway pressure devices.

    PubMed

    Park, Jong-Uk; Erdenebayar, Urtnasan; Joo, Eun-Yeon; Lee, Kyoung-Joung

    2017-06-27

    This paper proposes a method for classifying sleep-wakefulness and estimating sleep parameters using nasal pressure signals applicable to a continuous positive airway pressure (CPAP) device. In order to classify the sleep-wakefulness states of patients with sleep-disordered breathing (SDB), apnea-hypopnea and snoring events are first detected. Epochs detected as SDB are classified as sleep, and time-domain- and frequency-domain-based features are extracted from the epochs that are detected as normal breathing. Subsequently, sleep-wakefulness is classified using a support vector machine (SVM) classifier in the normal breathing epoch. Finally, four sleep parameters-sleep onset, wake after sleep onset, total sleep time and sleep efficiency-are estimated based on the classified sleep-wakefulness. In order to develop and test the algorithm, 110 patients diagnosed with SDB participated in this study. Ninety of the subjects underwent full-night polysomnography (PSG) and twenty underwent split-night PSG. The subjects were divided into 50 patients of a training set (full/split: 42/8), 30 of a validation set (full/split: 24/6) and 30 of a test set (full/split: 24/6). In the experiments conducted, sleep-wakefulness classification accuracy was found to be 83.2% in the test set, compared with the PSG scoring results of clinical experts. Furthermore, all four sleep parameters showed higher correlations than the results obtained via PSG (r  ⩾  0.84, p  <  0.05). In order to determine whether the proposed method is applicable to CPAP, sleep-wakefulness classification performances were evaluated for each CPAP in the split-night PSG data. The results indicate that the accuracy and sensitivity of sleep-wakefulness classification by CPAP variation shows no statistically significant difference (p  <  0.05). The contributions made in this study are applicable to the automatic classification of sleep-wakefulness states in CPAP devices and evaluation of the quality of sleep.

  5. Investigations of Air-cooled Turbine Rotors for Turbojet Engines II : Mechanical Design, Stress Analysis, and Burst Test of Modified J33 Split-disk Rotor / Richard H. Kemp and Merland L. Moseson

    NASA Technical Reports Server (NTRS)

    Kemp, Richard H; Moseson, Merland L

    1952-01-01

    A full-scale J33 air-cooled split turbine rotor was designed and spin-pit tested to destruction. Stress analysis and spin-pit results indicated that the rotor in a J33 turbojet engine, however, showed that the rear disk of the rotor operated at temperatures substantially higher than the forward disk. An extension of the stress analysis to include the temperature difference between the two disks indicated that engine modifications are required to permit operation of the two disks at more nearly the same temperature level.

  6. Pseudospin-orbit splitting and its consequences for the central depression in nuclear density

    NASA Astrophysics Data System (ADS)

    Li, Jia Jie; Long, Wen Hui; Song, Jun Ling; Zhao, Qiang

    2016-05-01

    The occurrence of the bubble-like structure has been studied, in the light of pseudospin degeneracy, within the relativistic Hartree-Fock-Bogoliubov (RHFB) theory. It is concluded that the charge/neutron bubble-like structure is predicted to occur in the mirror system of {34Si,34Ca } commonly by the selected Lagrangians, due to the persistence of Z (N )=14 subshell gaps above which the π (ν ) 2 s1 /2 states are not occupied. However, for the popular candidate 46Ar, the RHFB Lagrangian PKA1 does not support the occurrence of the bubble-like structure in the charge (proton) density profiles, due to the almost degenerate pseudospin doublet {π 2 s1 /2,π 1 d3 /2} and coherent pairing effects. The formation of a semibubble in heavy nuclei is less possible as a result of small pseudospin-orbit (PSO) splitting, while it tends to appear at Z =120 superheavy systems which coincides with large PSO splitting of the doublet {π 3 p3 /2,π 2 f5 /2} and couples with significant shell effects. Pairing correlations, which can work against bubble formation, significantly affect the PSO splitting. Furthermore, we found that the influence on semibubble formation due to different types of pairing interactions is negligible. The quenching of the spin-orbit splitting in the p orbit has been also stressed, and it may be considered the hallmark for semibubble nuclei.

  7. Split Nitrogen Application Improves Wheat Baking Quality by Influencing Protein Composition Rather Than Concentration.

    PubMed

    Xue, Cheng; Auf'm Erley, Gunda Schulte; Rossmann, Anne; Schuster, Ramona; Koehler, Peter; Mühling, Karl-Hermann

    2016-01-01

    The use of late nitrogen (N) fertilization (N application at late growth stages of wheat, e.g., booting, heading or anthesis) to improve baking quality of wheat has been questioned. Although it increases protein concentration, the beneficial effect on baking quality (bread loaf volume) needs to be clearly understood. Two pot experiments were conducted aiming to evaluate whether late N is effective under controlled conditions and if these effects result from increased N rate or N splitting. Late N fertilizers were applied either as additional N or split from the basal N at late boot stage or heading in the form of nitrate-N or urea. Results showed that late N fertilization improved loaf volume of wheat flour by increasing grain protein concentration and altering its composition. Increasing N rate mainly enhanced grain protein quantitatively. However, N splitting changed grain protein composition by enhancing the percentages of gliadins and glutenins as well as certain high molecular weight glutenin subunits (HMW-GS), which led to an improved baking quality of wheat flour. The late N effects were greater when applied as nitrate-N than urea. The proportions of glutenin and x-type HMW-GS were more important than the overall protein concentration in determining baking quality. N splitting is more effective in improving wheat quality than the increase in the N rate by late N, which offers the potential to cut down N fertilization rates in wheat production systems.

  8. Split Nitrogen Application Improves Wheat Baking Quality by Influencing Protein Composition Rather Than Concentration

    PubMed Central

    Xue, Cheng; auf’m Erley, Gunda Schulte; Rossmann, Anne; Schuster, Ramona; Koehler, Peter; Mühling, Karl-Hermann

    2016-01-01

    The use of late nitrogen (N) fertilization (N application at late growth stages of wheat, e.g., booting, heading or anthesis) to improve baking quality of wheat has been questioned. Although it increases protein concentration, the beneficial effect on baking quality (bread loaf volume) needs to be clearly understood. Two pot experiments were conducted aiming to evaluate whether late N is effective under controlled conditions and if these effects result from increased N rate or N splitting. Late N fertilizers were applied either as additional N or split from the basal N at late boot stage or heading in the form of nitrate-N or urea. Results showed that late N fertilization improved loaf volume of wheat flour by increasing grain protein concentration and altering its composition. Increasing N rate mainly enhanced grain protein quantitatively. However, N splitting changed grain protein composition by enhancing the percentages of gliadins and glutenins as well as certain high molecular weight glutenin subunits (HMW-GS), which led to an improved baking quality of wheat flour. The late N effects were greater when applied as nitrate-N than urea. The proportions of glutenin and x-type HMW-GS were more important than the overall protein concentration in determining baking quality. N splitting is more effective in improving wheat quality than the increase in the N rate by late N, which offers the potential to cut down N fertilization rates in wheat production systems. PMID:27313585

  9. The relative importance of genetic and nongenetic inheritance in relation to trait plasticity in Callosobruchus maculatus.

    PubMed

    Hallsson, L R; Chenoweth, S F; Bonduriansky, R

    2012-12-01

    A trait's response to natural selection will reflect the nature of the inheritance mechanisms that mediate the transmission of variation across generations. The relative importance of genetic and nongenetic mechanisms of inheritance is predicted to be related to the degree of trait plasticity, with nongenetic inheritance playing a greater role in the cross-generational transmission of more plastic traits. However, this prediction has never been tested. We investigated the influence of genetic effects and nongenetic parental effects in two morphological traits differing in degree of plasticity by manipulating larval diet quality within a cross-generational split-brood experiment using the seed beetle Callososbuchus maculatus. In line with predictions, we found that the more plastic trait (elytron length) is strongly influenced by both maternal and paternal effects whereas genetic variance is undetectable. In contrast, the less plastic trait (first abdominal sternite length) is not influenced by parental effects but exhibits abundant genetic variance. Our findings support the hypothesis that environment-dependent parental effects may play a particularly important role in highly plastic traits and thereby affect the evolutionary response of such traits. © 2012 The Authors. Journal of Evolutionary Biology © 2012 European Society For Evolutionary Biology.

  10. Influence of different crosshead speeds on diametral tensile strength of a methacrylate based resin composite: An in-vitro study

    PubMed Central

    Sood, Anubhav; Ramarao, Sathyanarayanan; Carounanidy, Usha

    2015-01-01

    Aim: The aim was to evaluate the influence of different crosshead speeds on diametral tensile strength (DTS) of a resin composite material (Tetric N-Ceram). Materials and Methods: The DTS of Tetric N-Ceram was evaluated using four different crosshead speeds 0.5 mm/min (DTS 1), 1 mm/min (DTS 2), 5 mm/min (DTS 3), 10 mm/min (DTS 4). A total of 48 specimens were prepared and divided into four subgroups with 12 specimens in each group. Specimens were made using stainless steel split custom molds of dimensions 6 mm diameter and 3 mm height. The specimens were stored in distilled water at room temperature for 24 h. Universal testing machine was used and DTS values were calculated in MPa. Results: Analysis of variance was used to compare the four groups. Higher mean DTS value was recorded in DTS 2 followed by DTS 4, DTS 1, and DTS 3, respectively. However, the difference in mean tensile strength between the groups was not statistically significant (P > 0.05). Conclusion: The crosshead speed variation between 0.5 and 10 mm/min does not seem to influence the DTS of a resin composite. PMID:26069407

  11. Influence of different crosshead speeds on diametral tensile strength of a methacrylate based resin composite: An in-vitro study.

    PubMed

    Sood, Anubhav; Ramarao, Sathyanarayanan; Carounanidy, Usha

    2015-01-01

    The aim was to evaluate the influence of different crosshead speeds on diametral tensile strength (DTS) of a resin composite material (Tetric N-Ceram). The DTS of Tetric N-Ceram was evaluated using four different crosshead speeds 0.5 mm/min (DTS 1), 1 mm/min (DTS 2), 5 mm/min (DTS 3), 10 mm/min (DTS 4). A total of 48 specimens were prepared and divided into four subgroups with 12 specimens in each group. Specimens were made using stainless steel split custom molds of dimensions 6 mm diameter and 3 mm height. The specimens were stored in distilled water at room temperature for 24 h. Universal testing machine was used and DTS values were calculated in MPa. Analysis of variance was used to compare the four groups. Higher mean DTS value was recorded in DTS 2 followed by DTS 4, DTS 1, and DTS 3, respectively. However, the difference in mean tensile strength between the groups was not statistically significant (P > 0.05). The crosshead speed variation between 0.5 and 10 mm/min does not seem to influence the DTS of a resin composite.

  12. Nitrogen split dose fertilization, plant age and frost effects on phytochemical content and sensory properties of curly kale (Brassica oleracea L. var. sabellica).

    PubMed

    Groenbaek, Marie; Jensen, Sidsel; Neugart, Susanne; Schreiner, Monika; Kidmose, Ulla; Kristensen, Hanne L

    2016-04-15

    We investigated how concentrations of sensory relevant compounds: glucosinolates (GLSs), flavonoid glycosides, hydroxycinnamic acid derivatives and sugars in kale responded to split dose and reduced nitrogen (N) fertilization, plant age and controlled frost exposure. In addition, frost effects on sensory properties combined with N supply were assessed. Seventeen week old kale plants showed decreased aliphatic GLSs at split dose N fertilization; whereas reduced N increased aliphatic and total GLSs. Ontogenetic effects were demonstrated for all compounds: sugars, aliphatic and total GLSs increased throughout plant development, whereas kaempferol and total flavonoid glycosides showed higher concentrations in 13 week old plants. Controlled frost exposure altered sugar composition slightly, but not GLSs or flavonoid glycosides. Reduced N supply resulted in less bitterness, astringency and pungent aroma, whereas frost exposure mainly influenced aroma and texture. N treatment explained most of the sensory variation. Producers should not rely on frost only to obtain altered sensory properties. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Upper mantle anisotropy from teleseismic SKS splitting beneath Lützow-Holm Bay Region, East Antarctica

    USGS Publications Warehouse

    Usui, Y.; Kanao, M.; Kubo, A.; Hiramatsu, Y.; Negishi, H.

    2007-01-01

    Investigations of SKS wave splitting of teleseismic events from digital seismographs recorded at eight stations around the Lützow-Holm Bay Region have lead to understanding the evolution of the Antarctic Plate. The observed delay times of SKS splitting are up to 1.3 s, which are generally equal to the global average. A two-layer model reveals that the lower layer anisotropy is caused by the recent asthenospheric flow, as compared with the Absolute Plate Motion by the HS3-NUVEL1 model. The upper layer anisotropy corresponds well to polarization of NE–SW convergence direction between East and West Gondwana in Pan-African age. We suggest that the upper layer anisotropy was formed during Pan-African orogeny and was possibly influenced by the preexisting structure during Gondwana break-up. The origin of anisotropy is the Lattice Preferred Orientation of olivine which was caused by both paleo-tectonic events and the recent asthenospheric flow.

  14. Magnetic thin-film split-domain current sensor-recorder

    DOEpatents

    Hsieh, Edmund J.

    1979-01-01

    A sensor-recorder for recording a representation of the direction and peak amplitude of a transient current. A magnetic thin film is coated on a glass substrate under the influence of a magnetic field so that the finished film is magnetically uniaxial and anisotropic. The film is split into two oppositely magnetized contiguous domains with a central boundary by subjecting adjacent portions of the film simultaneously to magnetic fields that are opposed 180.degree.. With the split-domain sensor-recorder placed with the film plane and domain boundary either perpendicular or parallel to the expected conductive path of a transient current, the occurrence of the transient causes switching of a portion of one domain to the direction of the other domain. The amount of the switched domain portion is indicative of the amplitude of the peak current of the transient, while the particular domain that is switched is indicative of the direction of the current. The resulting domain patterns may be read with a passive magnetic tape viewer.

  15. Global Simulation of Proton Precipitation Due to Field Line Curvature During Substorms

    NASA Technical Reports Server (NTRS)

    Gilson, M. L.; Raeder, J.; Donovan, E.; Ge, Y. S.; Kepko, L.

    2012-01-01

    The low latitude boundary of the proton aurora (known as the Isotropy Boundary or IB) marks an important boundary between empty and full downgoing loss cones. There is significant evidence that the IB maps to a region in the magnetosphere where the ion gyroradius becomes comparable to the local field line curvature. However, the location of the IB in the magnetosphere remains in question. In this paper, we show simulated proton precipitation derived from the Field Line Curvature (FLC) model of proton scattering and a global magnetohydrodynamic simulation during two substorms. The simulated proton precipitation drifts equatorward during the growth phase, intensifies at onset and reproduces the azimuthal splitting published in previous studies. In the simulation, the pre-onset IB maps to 7-8 RE for the substorms presented and the azimuthal splitting is caused by the development of the substorm current wedge. The simulation also demonstrates that the central plasma sheet temperature can significantly influence when and where the azimuthal splitting takes place.

  16. Accelerating locomotor savings in learning: compressing four training days to one.

    PubMed

    Day, Kevin A; Leech, Kristan A; Roemmich, Ryan T; Bastian, Amy J

    2018-06-01

    Acquiring new movements requires the capacity of the nervous system to remember previously experienced motor patterns. The phenomenon of faster relearning after initial learning is termed "savings." Here we studied how savings of a novel walking pattern develops over several days of practice and how this process can be accelerated. We introduced participants to a split-belt treadmill adaptation paradigm for 30 min for 5 consecutive days. By training day 5, participants were able to produce near-perfect performance when switching between split and tied-belt environments. We found that this was due to their ability to shift specific elements of their stepping pattern to account for the split treadmill speeds from day to day. We also applied a state-space model to further characterize multiday locomotor savings. We then explored methods of achieving comparable savings with less total training time. We studied people training only on day 1, with either one extended split-belt exposure or alternating four times between split-belt and tied-belt conditions rapidly in succession. Both of these single-day training groups were tested again on day 5. Experiencing four abbreviated exposures on day 1 improved the performance on day 5 compared with one extended exposure on day 1. Moreover, this abbreviated group performed similarly to the group that trained for 4 consecutive days before testing on day 5, despite only having one-quarter of the total training time. These results demonstrate that we can leverage training structure to achieve a high degree of performance while minimizing training sessions. NEW & NOTEWORTHY Learning a new movement requires repetition. Here, we demonstrate how to more efficiently train an adapted walking pattern. By compressing split-belt treadmill training delivered over 4 days to four abbreviated bouts of training delivered on the first day of training, we were able to induce equivalent savings over a 5-day span. These results suggest that we can manipulate the delivery of training to most efficiently drive multiday learning of a novel walking pattern.

  17. Mutation induction in haploid yeast after split-dose radiation-exposure. I. Fractionated UV-irradiation.

    PubMed

    Schenk, K; Zölzer, F; Kiefer, J

    1989-01-01

    Mutation induction was investigated in wild-type haploid yeast Saccharomyces cerevisiae after split-dose UV-irradiation. Cells were exposed to fractionated 254 nm-UV-doses separated by intervals from 0 to 6 h with incubation either on non-nutrient or nutrient agar between. The test parameter was resistance to canavanine. If modifications of sensitivity due to incubation are appropriately taken into account there is no change of mutation frequency.

  18. Perspectives on Interlanguage Phonetics and Phonology.

    ERIC Educational Resources Information Center

    Monroy, Rafael, Ed.; Gutierrez, Francisco, Ed.

    2001-01-01

    Articles in this special issue include the following: "Allophonic Splits in L2 Phonology: The Questions of Learnability" (Fred R. Eckman, Abdullah Elreyes, Gregory K. Iverson); "Native Language Influence in Learners' Assessment of English Focus" (M. L. Garcia Lecumberri); "Obstruent Voicing in English and Polish. A…

  19. TCF and Groucho-related genes influence pituitary growth and development.

    PubMed

    Brinkmeier, Michelle L; Potok, Mary Anne; Cha, Kelly B; Gridley, Thomas; Stifani, Stefano; Meeldijk, Jan; Clevers, Hans; Camper, Sally A

    2003-11-01

    Mutations in the prophet of PIT1 gene (PROP1) are the most common cause of multiple pituitary hormone deficiency in humans; however, the mechanism of PROP1 action is not well understood. We report that Prop1 is essential for dorsally restricted expression of a Groucho-related gene, transducin-like enhancer of split 3 (Tle3), which encodes a transcriptional corepressor. Deficiency of a related gene, amino terminal enhancer of split (Aes), causes pituitary anomalies and growth insufficiency. TLE3 and AES have been shown to interact with TCF/LEF (transcripiton factors of the T cell-specific and lymphoid enhancer specific group) family members in cell culture systems. In the absence of TCF4 (Tcf7L2), Prop1 levels are elevated, pituitary hyperplasia ensues and palate closure is abnormal. Thus, we demonstrate that Tcf4 and Aes influence pituitary growth and development, and place Tcf4 and Tle3 in the genetic hierarchy with Prop1.

  20. Enhanced Bifunctional Oxygen Catalysis in Strained LaNiO 3 Perovskites

    DOE PAGES

    Petrie, Jonathan R.; Cooper, Valentino R.; Freeland, John W.; ...

    2016-02-11

    Strain is known to greatly influence low-temperature oxygen electrocatalysis on noble metal films, leading to significant enhancements in bifunctional activity essential for fuel cells and metal-air batteries. Still, its catalytic impact on transition-metal oxide thin films, such as perovskites, is not widely understood. Here, we epitaxially strain the conducting perovskite LaNiO 3 to systematically determine its influence on both the oxygen reduction and oxygen evolution reaction. Uniquely, we found that compressive strain could significantly enhance both reactions, yielding a bifunctional catalyst that surpasses the performance of noble metals such as Pt. We attribute the improved bifunctionality to strain-induced splitting ofmore » the e g orbitals, which can customize orbital asymmetry at the surface. Lastly, analogous to strain-induced shifts in the d-band center of noble metals relative to the Fermi level, such splitting can dramatically affect catalytic activity in this perovskite and other potentially more active oxides.« less

  1. [The Scope, Quality and Safety Requirements of Drug Abuse Testing].

    PubMed

    Küme, Tuncay; Karakükcü, Çiğdem; Pınar, Aslı; Coşkunol, Hakan

    2017-01-01

    The aim of this review is to inform about the scopes and requirements of drug abuse testing. Drug abuse testing is one of the tools for determination of drug use. It must fulfill the quality and safety requirements in judgmental legal and administrative decisions. Drug abuse testing must fulfill some requirements like selection of the appropriate test matrix, appropriate screening test panel, sampling in detection window, patient consent, identification of the donor, appropriate collection site, sample collection with observation, identification and control of the sample, specimen custody chain in preanalytical phase; analysis in authorized laboratories, specimen validity tests, reliable testing METHODS, strict quality control, two-step analysis in analytical phase; storage of the split specimen, confirmation of the split specimen in the objection, result custody chain, appropriate cut-off concentration, the appropriate interpretation of the result in postanalytical phase. The workflow and analytical processes of drug abuse testing are explained in last regulation of the Department of Medical Laboratory Services, Ministry of Health in Turkey. The clinical physicians have to know and apply the quality and safety requirements in drug abuse testing according to last regulations in Turkey.

  2. [Adhesion of sealer cements to dentin with and without smear layer].

    PubMed

    Gettleman, B H; Messer, H H; ElDeeb, M E

    1991-01-01

    The influence of a smear layer on the adhesion of sealer cements to dentin was assessed in recently extracted human anterior teeth. A total of 120 samples was tested, 40 per sealer; 20 each with and without the smear layer. The teeth were split longitudinally, and the internal surfaces were ground flat. One-half of each tooth was left with the smear layer intact, while the other half had the smear removed by washing for 3 min with 17% EDTA followed by 5.25% NaOCI. Evidence of the ability to remove the smear layer was verified by scanning electron microscopy. Using a specially designed jig, the sealer was placed into a 4-mm wide x 4 mm deep well which was then set onto the tooth.

  3. Polymer concrete overlay test program : final report.

    DOT National Transportation Integrated Search

    1981-12-01

    The results in this report were obtained during the test program which began in 1973. Physical properties of various polymer concretes are listed. They include compressive strength, splitting tensile strength, bond strength, the modulus of elasticity...

  4. Characteristics of the gait adaptation process due to split-belt treadmill walking under a wide range of right-left speed ratios in humans

    PubMed Central

    Ogawa, Tetsuya; Yamamoto, Shin-Ichiro; Nakazawa, Kimitaka

    2018-01-01

    The adaptability of human bipedal locomotion has been studied using split-belt treadmill walking. Most of previous studies utilized experimental protocol under remarkably different split ratios (e.g. 1:2, 1:3, or 1:4). While, there is limited research with regard to adaptive process under the small speed ratios. It is important to know the nature of adaptive process under ratio smaller than 1:2, because systematic evaluation of the gait adaptation under small to moderate split ratios would enable us to examine relative contribution of two forms of adaptation (reactive feedback and predictive feedforward control) on gait adaptation. We therefore examined a gait behavior due to on split-belt treadmill adaptation under five belt speed difference conditions (from 1:1.2 to 1:2). Gait parameters related to reactive control (stance time) showed quick adjustments immediately after imposing the split-belt walking in all five speed ratios. Meanwhile, parameters related to predictive control (step length and anterior force) showed a clear pattern of adaptation and subsequent aftereffects except for the 1:1.2 adaptation. Additionally, the 1:1.2 ratio was distinguished from other ratios by cluster analysis based on the relationship between the size of adaptation and the aftereffect. Our findings indicate that the reactive feedback control was involved in all the speed ratios tested and that the extent of reaction was proportionally dependent on the speed ratio of the split-belt. On the contrary, predictive feedforward control was necessary when the ratio of the split-belt was greater. These results enable us to consider how a given split-belt training condition would affect the relative contribution of the two strategies on gait adaptation, which must be considered when developing rehabilitation interventions for stroke patients. PMID:29694404

  5. Numerical and analytical modeling of the end-loaded split (ELS) test specimens made of multi-directional coupled composite laminates

    NASA Astrophysics Data System (ADS)

    Samborski, Sylwester; Valvo, Paolo S.

    2018-01-01

    The paper deals with the numerical and analytical modelling of the end-loaded split test for multi-directional laminates affected by the typical elastic couplings. Numerical analysis of three-dimensional finite element models was performed with the Abaqus software exploiting the virtual crack closure technique (VCCT). The results show possible asymmetries in the widthwise deflections of the specimen, as well as in the strain energy release rate (SERR) distributions along the delamination front. Analytical modelling based on a beam-theory approach was also conducted in simpler cases, where only bending-extension coupling is present, but no out-of-plane effects. The analytical results matched the numerical ones, thus demonstrating that the analytical models are feasible for test design and experimental data reduction.

  6. Comparative Study on the Different Testing Techniques in Tree Classification for Detecting the Learning Motivation

    NASA Astrophysics Data System (ADS)

    Juliane, C.; Arman, A. A.; Sastramihardja, H. S.; Supriana, I.

    2017-03-01

    Having motivation to learn is a successful requirement in a learning process, and needs to be maintained properly. This study aims to measure learning motivation, especially in the process of electronic learning (e-learning). Here, data mining approach was chosen as a research method. For the testing process, the accuracy comparative study on the different testing techniques was conducted, involving Cross Validation and Percentage Split. The best accuracy was generated by J48 algorithm with a percentage split technique reaching at 92.19 %. This study provided an overview on how to detect the presence of learning motivation in the context of e-learning. It is expected to be good contribution for education, and to warn the teachers for whom they have to provide motivation.

  7. A hybrid flowshop scheduling model considering dedicated machines and lot-splitting for the solar cell industry

    NASA Astrophysics Data System (ADS)

    Wang, Li-Chih; Chen, Yin-Yann; Chen, Tzu-Li; Cheng, Chen-Yang; Chang, Chin-Wei

    2014-10-01

    This paper studies a solar cell industry scheduling problem, which is similar to traditional hybrid flowshop scheduling (HFS). In a typical HFS problem, the allocation of machine resources for each order should be scheduled in advance. However, the challenge in solar cell manufacturing is the number of machines that can be adjusted dynamically to complete the job. An optimal production scheduling model is developed to explore these issues, considering the practical characteristics, such as hybrid flowshop, parallel machine system, dedicated machines, sequence independent job setup times and sequence dependent job setup times. The objective of this model is to minimise the makespan and to decide the processing sequence of the orders/lots in each stage, lot-splitting decisions for the orders and the number of machines used to satisfy the demands in each stage. From the experimental results, lot-splitting has significant effect on shortening the makespan, and the improvement effect is influenced by the processing time and the setup time of orders. Therefore, the threshold point to improve the makespan can be identified. In addition, the model also indicates that more lot-splitting approaches, that is, the flexibility of allocating orders/lots to machines is larger, will result in a better scheduling performance.

  8. Thermostability promotes the cooperative function of split adenylate kinases.

    PubMed

    Nguyen, Peter Q; Liu, Shirley; Thompson, Jeremy C; Silberg, Jonathan J

    2008-05-01

    Proteins can often be cleaved to create inactive polypeptides that associate into functional complexes through non-covalent interactions, but little is known about what influences the cooperative function of the ensuing protein fragments. Here, we examine whether protein thermostability affects protein fragment complementation by characterizing the function of split adenylate kinases from the mesophile Bacillus subtilis (AKBs) and the hyperthermophile Thermotoga neapolitana (AKTn). Complementation studies revealed that the split AKTn supported the growth of Escherichia coli with a temperature-sensitive AK, but not the fragmented AKBs. However, weak complementation occurred when the AKBs fragments were fused to polypeptides that strongly associate, and this was enhanced by a Q16L mutation that thermostabilizes the full-length protein. To examine how the split AK homologs differ in structure and function, their catalytic activity, zinc content, and circular dichroism spectra were characterized. The reconstituted AKTn had higher levels of zinc, greater secondary structure, and >10(3)-fold more activity than the AKBs pair, albeit 17-fold less active than full-length AKTn. These findings provide evidence that the design of protein fragments that cooperatively function can be improved by choosing proteins with the greatest thermostability for bisection, and they suggest that this arises because hyperthermophilic protein fragments exhibit greater residual structure compared to their mesophilic counterparts.

  9. Gifford-McMahon refrigerator with split cold head

    NASA Technical Reports Server (NTRS)

    Forth, H. J.; Heisig, R.; Klein, H. H.

    1983-01-01

    Leybold-Heraeus Co. have developed, built and successfully tested a Gifford-McMahon cryocooler with splitted cold head for cooling a cryopump. The refrigerating part of the cold head and the gas flow control device have been separated (splitted cold head) and the distance between them is bridged by only two thin lines for carrying the working gas. Due to this separation the size of the refrigerating part is virtually defined only by the size of the displacers whilst the gas flow control device can be of any desired design. It has been shown that dimensioning of the connecting lines and the corresponding losses became less critical with increasing size of the expander, but additional cooling in proportion to the refrigerating capacity is required.

  10. Split Node and Stress Glut Methods for Dynamic Rupture Simulations in Finite Elements.

    NASA Astrophysics Data System (ADS)

    Ramirez-Guzman, L.; Bielak, J.

    2008-12-01

    I present two numerical techniques to solve the Dynamic problem. I revisit and modify the Split Node approach and introduce a Stress Glut type Method. Both algorithms are implemented using a iso/sub- parametric FEM solver. In the first case, I discuss the formulation and perform an analysis of convergence for different orders of approximation for the acoustic case. I describe the algorithm of the second methodology as well as the assumptions made. The key to the new technique is to have an accurate representation of the traction. Thus, I devote part of the discussion to analyze the tractions for a simple example. The sensitivity of the method is tested by comparing against Split Node solutions.

  11. Numerical Simulation on the Dynamic Splitting Tensile Test of reinforced concrete

    NASA Astrophysics Data System (ADS)

    Zhao, Zhuan; Jia, Haokai; Jing, Lin

    2018-03-01

    The research for crack resistance was of RC was based on the split Hopkinson bar and numerical simulate software LS-DYNA3D. In the research, the difference of dynamic splitting failure modes between plane concrete and reinforced concrete were completed, and the change rule of tensile stress distribution with reinforcement ratio was studied; also the effect rule with the strain rate and the crack resistance was also discussed by the radial tensile stress time history curve of RC specimen under different loading speeds. The results shows that the reinforcement in the concrete can impede the crack extension, defer the failure time of concrete, increase the tension intensity of concrete; with strain rate of concrete increased, the crack resistance of RC increased.

  12. Split-Session Focus Group Interviews in the Naturalistic Setting of Family Medicine Offices

    PubMed Central

    Fetters, Michael D.; Guetterman, Timothy C.; Power, Debra; Nease, Donald E.

    2016-01-01

    PURPOSE When recruiting health care professionals to focus group interviews, investigators encounter challenges such as busy clinic schedules, recruitment, and a desire to get candid responses from diverse participants. We sought to overcome these challenges using an innovative, office-based, split-session focus group procedure in a project that elicited feedback from family medicine practices regarding a new preventive services model. This procedure entails allocating a portion of time to the entire group and the remaining time to individual subgroups. We discuss the methodologic procedure and the implications of using this approach for data collection. METHODS We conducted split-session focus groups with physicians and staff in 4 primary care practices. The procedure entailed 3 sessions, each lasting 30 minutes: the moderator interviewed physicians and staff together, physicians alone, and staff alone. As part of the focus group interview, we elicited and analyzed participant comments about the split-session format and collected observational field notes. RESULTS The split-session focus group interviews leveraged the naturalistic setting of the office for context-relevant discussion. We tested alternate formats that began in the morning and at lunchtime, to parallel each practice’s workflow. The split-session approach facilitated discussion of topics primarily relevant to staff among staff, topics primarily relevant to physicians among physicians, and topics common to all among all. Qualitative feedback on this approach was uniformly positive. CONCLUSION A split-session focus group interview provides an efficient, effective way to elicit candid qualitative information from all members of a primary care practice in the naturalistic setting where they work. PMID:26755786

  13. Why we can't get along.

    PubMed

    Covington, Coline

    2005-02-01

    The author examines various arguments to explain the internal conflicts and schisms that have afflicted depth psychology since its beginnings. These arguments include the inevitable splits that occur in the course of institutional development, the inheritance of family schisms within the profession, historical, geographical and political influences, Freud's notion of the 'narcissism of minor differences' along with Gordon's idea of the need for enemies in establishing identity, and the impact of market forces. The author refutes these arguments and postulates instead that the profession attracts narcissistically disturbed members who have not been or cannot be sufficiently analysed. The profession needs to address this endemic narcissism in order to prevent further splitting and to establish a more ecumenical framework.

  14. Magneto-optic transmittance modulation observed in a hybrid graphene–split ring resonator terahertz metasurface

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zanotto, Simone; Pitanti, Alessandro; Lange, Christoph

    2015-09-21

    By placing a material in close vicinity of a resonant optical element, its intrinsic optical response can be tuned, possibly to a wide extent. Here, we show that a graphene monolayer, spaced a few tenths of nanometers from a split ring resonator metasurface, exhibits a magneto-optical response which is strongly influenced by the presence of the metasurface itself. This hybrid system holds promises in view of thin optical modulators, polarization rotators, and nonreciprocal devices, in the technologically relevant terahertz spectral range. Moreover, it could be chosen as the playground for investigating the cavity electrodynamics of Dirac fermions in the quantummore » regime.« less

  15. Influence of sugarbeet tillage Systems on the rhizoctonia-bacterial root rot complex

    USDA-ARS?s Scientific Manuscript database

    The Rhizoctonia-bacterial root rot complex in sugarbeet caused by Rhizoctonia solani and Leuconostoc mesenteroides can cause significant yield losses. To investigate the impact of different tillage systems on this complex, field studies were conducted from 2009 to 2011. Split blocks with conventio...

  16. Influence of sugarbeet tillage systems on rhizoctonia-bacterial root rot complex

    USDA-ARS?s Scientific Manuscript database

    The Rhizoctonia-bacterial root rot complex on sugarbeet caused by Rhizoctonia solani and Leuconostoc mesenteroides can cause significant yield losses. To investigate the impact of different tillage systems on this complex, field studies were conducted from 2009 to 2011. Split blocks with conventio...

  17. TWO-DIMENSIONAL MODELING OF AQUIFER REMEDIATION INFLUENCED BY SORPTION NONEQUILIBRIUM AND HYDRAULIC CONDUCTIVITY HETEROGENEITY

    EPA Science Inventory

    A computational model was developed to simulate aquifer remediation by pump and treat for a confined, perfectly stratified aquifer. A split-operator finite element numerical technique was utilized to incorporate flow field heterogeneity and nonequilibrium sorption into a two-dime...

  18. Indirect and direct tensile behavior of Devonian oil shales

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chong, K.P.; Chen, J.L.; Dana, G.F.

    1984-03-01

    Ultimate indirect tensile strengths of Devonian oil shales across the bedding planes is a mechanical property parameter important to predicting how oil shale will break. This is particularly important to in-situ fragmentation. The Split Cylinder Test was used to determine the indirect tensile strengths between the bedding planes. Test specimens, cored perpendicular to the bedding planes, representing oil shales of different oil yields taken from Silver Point Quad in DeKalb County, Tennessee and Friendship in Scioto County, Ohio, were subjected to the Split Cylinder Test. Linear regression equations relating ultimate tensile strength across the bedding planes to volume percent ofmore » organic matter in the rock were developed from the test data. In addition, direct tensile strengths were obtained between the bedding planes for the Tennessee oil shales. This property is important for the design of horizontal fractures in oil shales. Typical results were presented.« less

  19. On kinetic modelling for solar redox thermochemical H2O and CO2 splitting over NiFe2O4 for H2, CO and syngas production.

    PubMed

    Dimitrakis, Dimitrios A; Syrigou, Maria; Lorentzou, Souzana; Kostoglou, Margaritis; Konstandopoulos, Athanasios G

    2017-10-11

    This study aims at developing a kinetic model that can adequately describe solar thermochemical water and carbon dioxide splitting with nickel ferrite powder as the active redox material. The kinetic parameters of water splitting of a previous study are revised to include transition times and new kinetic parameters for carbon dioxide splitting are developed. The computational results show a satisfactory agreement with experimental data and continuous multicycle operation under varying operating conditions is simulated. Different test cases are explored in order to improve the product yield. At first a parametric analysis is conducted, investigating the appropriate duration of the oxidation and the thermal reduction step that maximizes the hydrogen yield. Subsequently, a non-isothermal oxidation step is simulated and proven as an interesting option for increasing the hydrogen production. The kinetic model is adapted to simulate the production yields in structured solar reactor components, i.e. extruded monolithic structures, as well.

  20. Analysis of progressive damage in thin circular laminates due to static-equivalent impact loads

    NASA Technical Reports Server (NTRS)

    Shivakumar, K. N.; Elber, W.; Illg, W.

    1983-01-01

    Clamped circular graphite/epoxy plates (25.4, 38.1, and 50.8 mm radii) with an 8-ply quasi-isotropic layup were analyzed for static-equivalent impact loads using the minimum-total-potential-energy method and the von Karman strain-displacement equations. A step-by-step incremental transverse displacement procedure was used to calculate plate load and ply stresses. The ply failure region was calculated using the Tsai-Wu criterion. The corresponding failure modes (splitting and fiber failure) were determined using the maximum stress criteria. The first-failure mode was splitting and initiated first in the bottom ply. The splitting-failure thresholds were relatively low and tended to be lower for larger plates than for small plates. The splitting-damage region in each ply was elongated in its fiber direction; the bottom ply had the largest damage region. The calculated damage region for the 25.4-mm-radius plate agreed with limited static test results from the literature.

  1. Surgical management of insertional calcific achilles tendinosis with a central tendon splitting approach.

    PubMed

    Johnson, Keith W; Zalavras, Charalampos; Thordarson, David B

    2006-04-01

    Insertional calcific Achilles tendinosis is a painful, frequently disabling condition. Numerous operative approaches for this problem have been described. This study evaluated the outcome of a central tendon splitting approach. Twenty-two patients were evaluated after a central tendon splitting approach for persistent insertional calcific Achilles tendinosis. Followup averaged 34 (11 to 64) months. Suture anchors were routinely used to augment the tendon insertion after debridement. An American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot score, shoewear comfort, and return to work were evaluated. A paired t-test was used to evaluate the results. Pain significantly improved from 7 points preoperatively to 33 points postoperatively (p < 0.001). Function improved significantly from 36 points to 46 points (p < 0.001). The ankle-hindfoot score improved from 53 points to 89 points (p < 0.001). Age older or younger than 50 years did not affect outcome. A central tendon splitting approach yielded good relief of pain with improved function, shoewear, and ability to work without painful postoperative scars.

  2. Evaluation of the split cantilever beam for Mode 3 delamination testing

    NASA Technical Reports Server (NTRS)

    Martin, Roderick H.

    1989-01-01

    A test rig for testing a thick split cantilever beam for scissoring delamination (mode 3) fracture toughness was developed. A 3-D finite element analysis was conducted on the test specimen to determine the strain energy release rate, G, distribution along the delamination front. The virtual crack closure technique was used to calculate the G components resulting from interlaminar tension, GI, interlaminar sliding shear, GII, and interlaminar tearing shear, GIII. The finite element analysis showed that at the delamination front no GI component existed, but a GII component was present in addition to a GIII component. Furthermore, near the free edges, the GII component was significantly higher than the GIII component. The GII/GIII ratio was found to increase with delamination length but was insensitive to the beam depth. The presence of GII at the delamination front was verified experimentally by examination of the failure surfaces. At the center of the beam, where the failure was in mode 3, there was significant fiber bridging. However, at the edges of the beam where the failure was in mode 3, there was no fiber bridging and mode 2 shear hackles were observed. Therefore, it was concluded that the split cantilever beam configuration does not represent a pure mode 3 test. The experimental work showed that the mode 2 fracture toughness, GIIc, must be less than the mode 3 fracture toughness, GIIIc. Therefore, a conservative approach to characterizing mode 3 delamination is to equate GIIIc to GIIc.

  3. Split-Stirling-cycle displacer linear-electric drive

    NASA Technical Reports Server (NTRS)

    Ackermann, R. A.; Bhate, S. K.; Byrne, D. V.

    1983-01-01

    The retrofit of a 1/4-W split-Stirling cooler with a linear driven on the displacer was achieved and its performance characterized. The objective of this work was to demonstrate that a small linear motor could be designed to meet the existing envelope specifications of the cooler and that an electric linear drive on the displacer could improve the cooler's reliability and performance. The paper describes the characteristics of this motor and presents cooler test results.

  4. CT volumetry is superior to nuclear renography for prediction of residual kidney function in living donors.

    PubMed

    Barbas, Andrew S; Li, Yanhong; Zair, Murtuza; Van, Julie A; Famure, Olusegun; Dib, Martin J; Laurence, Jerome M; Kim, S Joseph; Ghanekar, Anand

    2016-09-01

    Living kidney donor evaluation commonly includes nuclear renography to assess split kidney function and computed tomography (CT) scan to evaluate anatomy. To streamline donor workup and minimize exposure to radioisotopes, we sought to assess the feasibility of using proportional kidney volume from CT volumetry in lieu of nuclear renography. We examined the correlation between techniques and assessed their ability to predict residual postoperative kidney function following live donor nephrectomy. In a cohort of 224 live kidney donors, we compared proportional kidney volume derived by CT volumetry with split kidney function derived from nuclear renography and found only modest correlation (left kidney R(2) =26.2%, right kidney R(2) =26.7%). In a subset of 88 live kidney donors with serum creatinine measured 6 months postoperatively, we compared observed estimated glomerular filtration rate (eGFR) at 6 months with predicted eGFR from preoperative imaging. Compared to nuclear renography, CT volumetry more closely approximated actual observed postoperative eGFR for Chronic Kidney Disease Epidemiology Collaboration (J-test: P=.02, Cox-Pesaran test: P=.01) and Mayo formulas (J-test: P=.004, Cox-Pesaran test: P<.001). These observations support the use of CT volumetry for estimation of split kidney function in healthy individuals with normal kidney function and morphology. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. Semi-implicit iterative methods for low Mach number turbulent reacting flows: Operator splitting versus approximate factorization

    NASA Astrophysics Data System (ADS)

    MacArt, Jonathan F.; Mueller, Michael E.

    2016-12-01

    Two formally second-order accurate, semi-implicit, iterative methods for the solution of scalar transport-reaction equations are developed for Direct Numerical Simulation (DNS) of low Mach number turbulent reacting flows. The first is a monolithic scheme based on a linearly implicit midpoint method utilizing an approximately factorized exact Jacobian of the transport and reaction operators. The second is an operator splitting scheme based on the Strang splitting approach. The accuracy properties of these schemes, as well as their stability, cost, and the effect of chemical mechanism size on relative performance, are assessed in two one-dimensional test configurations comprising an unsteady premixed flame and an unsteady nonpremixed ignition, which have substantially different Damköhler numbers and relative stiffness of transport to chemistry. All schemes demonstrate their formal order of accuracy in the fully-coupled convergence tests. Compared to a (non-)factorized scheme with a diagonal approximation to the chemical Jacobian, the monolithic, factorized scheme using the exact chemical Jacobian is shown to be both more stable and more economical. This is due to an improved convergence rate of the iterative procedure, and the difference between the two schemes in convergence rate grows as the time step increases. The stability properties of the Strang splitting scheme are demonstrated to outpace those of Lie splitting and monolithic schemes in simulations at high Damköhler number; however, in this regime, the monolithic scheme using the approximately factorized exact Jacobian is found to be the most economical at practical CFL numbers. The performance of the schemes is further evaluated in a simulation of a three-dimensional, spatially evolving, turbulent nonpremixed planar jet flame.

  6. EXPERIMENTAL EVALUATION OF A NOVEL FULL-SCALE EVAPORATIVELY COOLED CONDENSER

    EPA Science Inventory

    The report compares the performance of a novel evaporatively cooled condenser with that of a conventional air-cooled condenser for a split-system heat pump. The system was tested in an environmentally controlled test chamber that is able to simulate test conditions as specified b...

  7. 75 FR 22581 - Energy Conservation Program for Commercial Equipment: Decision and Order Granting a Waiver to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-29

    .... (Mitsubishi) for a similar line of commercial multi-split air-conditioning systems: Testing laboratories...-conditioning systems: (1) Testing laboratories cannot test products with so many indoor units; (2) there are too many possible combinations of indoor and outdoor unit to test. The Daikin VRV-WIII systems have...

  8. An in vitro evaluation of rigid internal fixation techniques for sagittal split ramus osteotomies: setback surgery.

    PubMed

    Brasileiro, Bernardo Ferreira; Grotta-Grempel, Rafael; Ambrosano, Glaucia Maria Bovi; Passeri, Luis Augusto

    2012-04-01

    The aim of this study was to evaluate the biomechanical features of 3 different methods of rigid internal fixation for sagittal split ramus osteotomy for mandibular setback in vitro. Sixty polyurethane replicas of human hemimandibles were used as substrates, simulating a 5-mm setback surgery by sagittal split ramus osteotomy. These replicas served to reproduce 3 different techniques of fixation, including 1) a 4-hole plate and 4 monocortical screws (miniplate group), 2) a 4-hole plate and 4 monocortical screws with 1 additional bicortical positional screw (hybrid group), and 3) 3 bicortical positional screws in a traditional inverted-L pattern (inverted-L group). After fixation, hemimandibles were adapted to a test support and subjected to lateral torsional forces on the buccal molar surface and vertical cantilever loading on the incisal edge with an Instron 4411 mechanical testing unit. Peak loadings at 1, 3, 5, and 10 mm of displacement were recorded. Means and standard deviation were analyzed using analysis of variance and Tukey test with a 5% level of significance, and failures during tests were recorded. Regardless of the amount of displacement and direction of force, the miniplate group always showed the lowest load peak scores (P < .01) compared with the other fixation techniques. The hybrid group demonstrated behavior similar to the inverted-L group in lateral and vertical forces at any loading displacement (P > .05). Molar load tests required more force than incisal load tests to promote the same displacement in the mandibular setback model (P < .05). For mandibular setback surgery of 5 mm, this study concluded that the fixation technique based on the miniplate group was significantly less rigid than the fixation observed in the hybrid and inverted-L groups. Mechanically, adding 1 bicortical positional screw in the retromolar region in the miniplate technique may achieve the same stabilization offered by inverted-L fixation for mandibular sagittal split ramus osteotomy setback surgery in vitro. Copyright © 2012 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  9. Low speed aerodynamic characteristics of the GD/C B-18E3 booster

    NASA Technical Reports Server (NTRS)

    Carter, W. V.; Gallaher, W. H.

    1972-01-01

    A 0.02 scale model of the B-18E3 space shuttle booster was tested in a low speed wind tunnel to evaluate the low speed aerodynamic charactersitics. The basic configuration, including build-up, was tested at a Mach number of 0.201 and Reynolds number per foot of 1.39 million. The normal angle-of-attack range was -4 to +24 degrees in 2 degree increments, at sideslip angles of 0 and 5 degrees. Some lateral data were obtained at the sideslip angle range of -6 to 10 degrees at angles-of attack of 0, 10, and 15 degrees. Data were obtained for canard, split elevon, and split rudder deflections.

  10. Effect of strain rate and temperature on mechanical properties of selected building Polish steels

    NASA Astrophysics Data System (ADS)

    Moćko, Wojciech; Kruszka, Leopold

    2015-09-01

    Currently, the computer programs of CAD type are basic tool for designing of various structures under impact loading. Application of the numerical calculations allows to substantially reduce amount of time required for the design stage of such projects. However, the proper use of computer aided designing technique requires input data for numerical software including elastic-plastic models of structural materials. This work deals with the constitutive model developed by Rusinek and Klepaczko (RK) applied for the modelling of mechanical behaviour of selected grades structural St0S, St3SX, 18GS and 34GS steels and presents here results of experimental and empirical analyses to describe dynamic elastic-plastic behaviours of tested materials at wide range of temperature. In order to calibrate the RK constitutive model, series of compression tests at wide range of strain rates, including static, quasi-static and dynamic investigations at lowered, room and elevated temperatures, were carried out using two testing stands: servo-hydraulic machine and split Hopkinson bar. The results were analysed to determine influence of temperature and strain rate on visco-plastic response of tested steels, and show good correlation with experimental data.

  11. Investigation of Dynamic Force/Vibration Transmission Characteristics of Four-Square Type Gear Durability Test Machines

    NASA Technical Reports Server (NTRS)

    Kahraman, Ahmet

    2002-01-01

    In this study, design requirements for a dynamically viable, four-square type gear test machine are investigated. Variations of four-square type gear test machines have been in use for durability and dynamics testing of both parallel- and cross-axis gear set. The basic layout of these machines is illustrated. The test rig is formed by two gear pairs, of the same reduction ratio, a test gear pair and a reaction gear pair, connected to each other through shafts of certain torsional flexibility to form an efficient, closed-loop system. A desired level of constant torque is input to the circuit through mechanical (a split coupling with a torque arm) or hydraulic (a hydraulic actuator) means. The system is then driven at any desired speed by a small DC motor. The main task in hand is the isolation of the test gear pair from the reaction gear pair under dynamic conditions. Any disturbances originated at the reaction gear mesh might potentially travel to the test gearbox, altering the dynamic loading conditions of the test gear mesh, and hence, influencing the outcome of the durability or dynamics test. Therefore, a proper design of connecting structures becomes a major priority. Also, equally important is the issue of how close the operating speed of the machine is to the resonant frequencies of the gear meshes. This study focuses on a detailed analysis of the current NASA Glenn Research Center gear pitting test machine for evaluation of its resonance and vibration isolation characteristics. A number of these machines as the one illustrated has been used over last 30 years to establish an extensive database regarding the influence of the gear materials, processes surface treatments and lubricants on gear durability. This study is intended to guide an optimum design of next generation test machines for the most desirable dynamic characteristics.

  12. The influence of veteran race and psychometric testing on veterans affairs posttraumatic stress disorder (PTSD) disability exam outcomes.

    PubMed

    Marx, Brian P; Engel-Rebitzer, Eden; Bovin, Michelle J; Parker-Guilbert, Kelly S; Moshier, Samantha; Barretto, Kenneth; Szafranski, Derek; Gallagher, Matthew W; Holowka, Darren W; Rosen, Raymond C; Keane, Terence M

    2017-06-01

    This study examined the influence of veterans' race and examiners' use of psychometric testing during a Department of Veterans Affairs posttraumatic stress disorder (PTSD) disability examination on diagnostic and service connection status outcomes. Participants were 764 veterans enrolled in a national longitudinal registry. Current and lifetime PTSD diagnostic status was determined with the Structured Clinical Interview for DSM-IV (SCID) and was compared with PTSD diagnosis conferred upon veterans by their compensation and pension (C&P) examiners as well as with ultimate Veterans Affairs (VA) PTSD service connected status. The concordance rate between independent SCID current PTSD diagnosis and PTSD disability examination diagnosis was 70.4%, and between SCID lifetime PTSD diagnosis and PTSD disability examination diagnosis was 77.7%. Among veterans with current SCID diagnosed PTSD, Black veterans were significantly less likely than White veterans to receive a PTSD diagnosis from their C&P examiner (odds ratio [OR] = .39, p = .003, confidence interval [CI] = .20-.73). Among veterans without current SCID diagnosed PTSD, White veterans were significantly more likely than Black veterans to receive a PTSD diagnosis from their C&P examiner (OR = 4.07, p = .005, CI = 1.51-10.92). Splitting the sample by use of psychometric testing revealed that examinations that did not include psychometric testing demonstrated the same relation between veteran race and diagnostic concordance. However, for examinations in which psychometric testing was used, the racial disparity between SCID PTSD status and disability exam PTSD status was no longer significant. Results suggest that psychometric testing may reduce disparities in VA PTSD disability exam outcomes. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Influence of tillage systems on Rhizoctonia-bacterial root rot complex in sugar beet

    USDA-ARS?s Scientific Manuscript database

    The Rhizoctonia-bacterial root rot complex on sugarbeet caused by Rhizoctonia solani and Leuconostoc mesenteroides can cause significant yield losses. To investigate the impact of different tillage systems on this complex, field studies were conducted from 2009 to 2011. Split blocks with conventio...

  14. Nanostructured hematite for photoelectrochemical water splitting

    NASA Astrophysics Data System (ADS)

    Ling, Yichuan

    Solar water splitting is an environmentally friendly reaction of producing hydrogen gas. Since Honda and Fujishima first demonstrated solar water splitting in 1972 by using semiconductor titanium dioxide (TiO2) as photoanode in a photoelectrochemical (PEC) cell, extensive efforts have been invested into improving the solar-to-hydrogen (STH) conversion efficiency and lower the production cost of photoelectrochemical devices. In the last few years, hematite (alpha-Fe2O3) nanostructures have been extensively studied as photoanodes for PEC water splitting. Although nanostructured hematite can improve its photoelectrochemical water splitting performance to some extent, by increasing active sites for water oxidation and shortening photogenerated hole path length to semiconductor/electrolyte interface, the photoactivity of pristine hematite nanostructures is still limited by a number of factors, such as poor electrical conductivities and slow oxygen evolution reaction kinetics. Previous studies have shown that tin (Sn) as an n-type dopant can substantially enhance the photoactivity of hematite photoanodes by modifying their optical and electrical properties. In this thesis, I will first demonstrate an unintentional Sn-doping method via high temperature annealing of hematite nanowires grown on fluorine-doped tin oxide (FTO) substrate to enhance the donor density. In addition to introducing extrinsic dopants into semiconductors, the carrier densities of hematite can also be enhanced by creating intrinsic defects. Oxygen vacancies function as shallow donors for a number of hematite. In this regard, I have investigated the influence of oxygen content on thermal decomposition of FeOOH to induce oxygen vacancies in hematite. In the end, I have studied low temperature activation of hematite nanostructures.

  15. The effects of steroids in preventing facial oedema, pain, and neurosensory disturbances after bilateral sagittal split osteotomy: a randomized controlled trial.

    PubMed

    Widar, F; Kashani, H; Alsén, B; Dahlin, C; Rasmusson, L

    2015-02-01

    A randomized, prospective, controlled trial was conducted to determine the efficacy of single and repeated betamethasone doses on facial oedema, pain, and neurosensory disturbances after bilateral sagittal split osteotomy. Thirty-seven patients (mean age 23.62 years, range 17-62 years) with either mandibular prognathism or retrognathism were enrolled consecutively into the study and divided into three groups: control (n=12), repeated dose 4+8+4mg betamethasone (n=14), single dose 16mg betamethasone (n=11). The intake of diclofenac and paracetamol was assessed individually. Measurements of facial oedema, pain, and sensitivity in the lower lip/chin were obtained 1 day, 7 days, 2 months, and 6 months postoperatively. Furthermore, we investigated the possible influences of gender, age, total operating time, amount of bleeding, postoperative hospitalization, and advancement versus setback of the mandible. A significant difference (P=0.017) was observed in percentage change between the two test groups and the control group regarding facial oedema (1 day postoperatively). Less bleeding was associated with improved pain recovery over time (P=0.043). Patients who required higher postoperative dosages of analgesics due to pain had significantly delayed recovery of the inferior alveolar nerve at 6 months postoperatively (P<0.001). Betamethasone did not reduce neurosensory disturbances over time. Copyright © 2014 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  16. Environmental stability study of holographic solar spectrum splitting materials

    NASA Astrophysics Data System (ADS)

    Chrysler, Benjamin D.; Ayala Pelaez, Silvana; Wu, Yuechen; Vorndran, Shelby D.; Kostuk, Raymond K.

    2016-09-01

    In this study the impact of outdoor temperature variations and solar illumination exposure on spectral filter material and holographic optical elements is examined. Although holographic components have been shown to be useful for solar spectrum splitting designs, relatively little quantitative data exist to demonstrate the extent to which these materials can withstand outdoor conditions. As researchers seek to investigate practical spectrum splitting designs, the environmental stability of holographic materials should be considered as an important factor. In the experiment presented, two holographic materials, Covestro Bayfol HX photopolymer and dichromated gelatin, and 3M reflective polymer filter materials are exposed to outdoor conditions for a period of several months. The environmental effect on absorption, spectral and angular bandwidth, peak efficiency, and Bragg matching conditions for the holograms are examined. Spectral bandwidth and transmittance of the 3M reflective filter material are also monitored. Holographic gratings are recorded, measured, and mounted on glass substrates and then sealed with a glass cover plate. The test samples are then mounted on a photovoltaic panel to simulate realistic temperature conditions and placed at an outdoor test facility in Tucson, Arizona. A duplicate set of holograms and 3M filter material is stored as a control group and periodically compared over the test period.

  17. Cognitive Performance and Locomotor Adaptation in Persons With Anterior Cruciate Ligament Reconstruction.

    PubMed

    Stone, Amanda E; Roper, Jaimie A; Herman, Daniel C; Hass, Chris J

    2018-05-01

    Persons with anterior cruciate ligament reconstruction (ACLR) show deficits in gait and neuromuscular control following rehabilitation. This altered behavior extends to locomotor adaptation and learning, however the contributing factors to this observed behavior have yet to be investigated. The purpose of this study was to assess differences in locomotor adaptation and learning between ACLR and controls, and identify underlying contributors to motor adaptation in these individuals. Twenty ACLR individuals and 20 healthy controls (CON) agreed to participate in this study. Participants performed four cognitive and dexterity tasks (local version of Trail Making Test, reaction time test, electronic pursuit rotor test, and the Purdue pegboard). Three-dimensional kinematics were also collected while participants walked on a split-belt treadmill. ACLR individuals completed the local versions of Trails A and Trails B significantly faster than CON. During split-belt walking, ACLR individuals demonstrated smaller step length asymmetry during EARLY and LATE adaptation, smaller double support asymmetry during MID adaptation, and larger stance time asymmetry during DE-ADAPT compared with CON. ACLR individuals performed better during tasks that required visual attention and task switching and were less perturbed during split-belt walking compared to controls. Persons with ACLR may use different strategies than controls, cognitive or otherwise, to adapt locomotor patterns.

  18. Does rational selection of training and test sets improve the outcome of QSAR modeling?

    PubMed

    Martin, Todd M; Harten, Paul; Young, Douglas M; Muratov, Eugene N; Golbraikh, Alexander; Zhu, Hao; Tropsha, Alexander

    2012-10-22

    Prior to using a quantitative structure activity relationship (QSAR) model for external predictions, its predictive power should be established and validated. In the absence of a true external data set, the best way to validate the predictive ability of a model is to perform its statistical external validation. In statistical external validation, the overall data set is divided into training and test sets. Commonly, this splitting is performed using random division. Rational splitting methods can divide data sets into training and test sets in an intelligent fashion. The purpose of this study was to determine whether rational division methods lead to more predictive models compared to random division. A special data splitting procedure was used to facilitate the comparison between random and rational division methods. For each toxicity end point, the overall data set was divided into a modeling set (80% of the overall set) and an external evaluation set (20% of the overall set) using random division. The modeling set was then subdivided into a training set (80% of the modeling set) and a test set (20% of the modeling set) using rational division methods and by using random division. The Kennard-Stone, minimal test set dissimilarity, and sphere exclusion algorithms were used as the rational division methods. The hierarchical clustering, random forest, and k-nearest neighbor (kNN) methods were used to develop QSAR models based on the training sets. For kNN QSAR, multiple training and test sets were generated, and multiple QSAR models were built. The results of this study indicate that models based on rational division methods generate better statistical results for the test sets than models based on random division, but the predictive power of both types of models are comparable.

  19. A unified bond theory, probabilistic meso-scale modeling, and experimental validation of deformed steel rebar in normal strength concrete

    NASA Astrophysics Data System (ADS)

    Wu, Chenglin

    Bond between deformed rebar and concrete is affected by rebar deformation pattern, concrete properties, concrete confinement, and rebar-concrete interfacial properties. Two distinct groups of bond models were traditionally developed based on the dominant effects of concrete splitting and near-interface shear-off failures. Their accuracy highly depended upon the test data sets selected in analysis and calibration. In this study, a unified bond model is proposed and developed based on an analogy to the indentation problem around the rib front of deformed rebar. This mechanics-based model can take into account the combined effect of concrete splitting and interface shear-off failures, resulting in average bond strengths for all practical scenarios. To understand the fracture process associated with bond failure, a probabilistic meso-scale model of concrete is proposed and its sensitivity to interface and confinement strengths are investigated. Both the mechanical and finite element models are validated with the available test data sets and are superior to existing models in prediction of average bond strength (< 6% error) and crack spacing (< 6% error). The validated bond model is applied to derive various interrelations among concrete crushing, concrete splitting, interfacial behavior, and the rib spacing-to-height ratio of deformed rebar. It can accurately predict the transition of failure modes from concrete splitting to rebar pullout and predict the effect of rebar surface characteristics as the rib spacing-to-height ratio increases. Based on the unified theory, a global bond model is proposed and developed by introducing bond-slip laws, and validated with testing of concrete beams with spliced reinforcement, achieving a load capacity prediction error of less than 26%. The optimal rebar parameters and concrete cover in structural designs can be derived from this study.

  20. Series length used during trend analysis affects sensitivity to changes in progression rate in the ocular hypertension treatment study.

    PubMed

    Gardiner, Stuart K; Demirel, Shaban; De Moraes, Carlos Gustavo; Liebmann, Jeffrey M; Cioffi, George A; Ritch, Robert; Gordon, Mae O; Kass, Michael A

    2013-02-15

    Trend analysis techniques to detect glaucomatous progression typically assume a constant rate of change. This study uses data from the Ocular Hypertension Treatment Study to assess whether this assumption decreases sensitivity to changes in progression rate, by including earlier periods of stability. Series of visual fields (mean 24 per eye) completed at 6-month intervals from participants randomized initially to observation were split into subseries before and after the initiation of treatment (the "split-point"). The mean deviation rate of change (MDR) was derived using these entire subseries, and using only the window length (W) tests nearest the split-point, for different window lengths of W tests. A generalized estimating equation model was used to detect changes in MDR occurring at the split-point. Using shortened subseries with W = 7 tests, the MDR slowed by 0.142 dB/y upon initiation of treatment (P < 0.001), and the proportion of eyes showing "rapid deterioration" (MDR <-0.5 dB/y with P < 5%) decreased from 11.8% to 6.5% (P < 0.001). Using the entire sequence, no significant change in MDR was detected (P = 0.796), and there was no change in the proportion of eyes progressing (P = 0.084). Window lengths 6 ≤ W ≤ 9 produced similar benefits. Event analysis revealed a beneficial treatment effect in this dataset. This effect was not detected by linear trend analysis applied to entire series, but was detected when using shorter subseries of length between six and nine fields. Using linear trend analysis on the entire field sequence may not be optimal for detecting and monitoring progression. Nonlinear analyses may be needed for long series of fields. (ClinicalTrials.gov number, NCT00000125.).

  1. Alternative Refrigerant Evaluation for High-Ambient-Temperature Environments: R-22 and R-410A Alternatives for Mini-Split Air Conditioners

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abdelaziz, Omar; Shrestha, Som S.; Munk, Jeffrey D.

    The Oak Ridge National Laboratory (ORNL) High-Ambient-Temperature Evaluation Program for low– global warming potential (Low-GWP) Refrigerants aims to develop an understanding of the performance of low-GWP alternative refrigerants to hydrochlorofluorocarbon (HCFC) and hydrofluorocarbon (HFC) refrigerants in mini-split air conditioners under high-ambient-temperature conditions. This final report describes the parties involved, the alternative refrigerant selection process, the test procedures, and the final results.

  2. Operational Testing of Satellite based Hydrological Model (SHM)

    NASA Astrophysics Data System (ADS)

    Gaur, Srishti; Paul, Pranesh Kumar; Singh, Rajendra; Mishra, Ashok; Gupta, Praveen Kumar; Singh, Raghavendra P.

    2017-04-01

    Incorporation of the concept of transposability in model testing is one of the prominent ways to check the credibility of a hydrological model. Successful testing ensures ability of hydrological models to deal with changing conditions, along with its extrapolation capacity. For a newly developed model, a number of contradictions arises regarding its applicability, therefore testing of credibility of model is essential to proficiently assess its strength and limitations. This concept emphasizes to perform 'Hierarchical Operational Testing' of Satellite based Hydrological Model (SHM), a newly developed surface water-groundwater coupled model, under PRACRITI-2 program initiated by Space Application Centre (SAC), Ahmedabad. SHM aims at sustainable water resources management using remote sensing data from Indian satellites. It consists of grid cells of 5km x 5km resolution and comprises of five modules namely: Surface Water (SW), Forest (F), Snow (S), Groundwater (GW) and Routing (ROU). SW module (functions in the grid cells with land cover other than forest and snow) deals with estimation of surface runoff, soil moisture and evapotranspiration by using NRCS-CN method, water balance and Hragreaves method, respectively. The hydrology of F module is dependent entirely on sub-surface processes and water balance is calculated based on it. GW module generates baseflow (depending on water table variation with the level of water in streams) using Boussinesq equation. ROU module is grounded on a cell-to-cell routing technique based on the principle of Time Variant Spatially Distributed Direct Runoff Hydrograph (SDDH) to route the generated runoff and baseflow by different modules up to the outlet. For this study Subarnarekha river basin, flood prone zone of eastern India, has been chosen for hierarchical operational testing scheme which includes tests under stationary as well as transitory conditions. For this the basin has been divided into three sub-basins using three flow gauging sites as reference, viz., Muri, Jamshedpur and Ghatshila. Individual model set-up has been prepared for these sub-basins and calibration and validation using Split-sample test, first level of operational testing scheme is in progress. Subsequently for geographic transposability, Proxy-basin test will be done using Muri and Jamshedpur as proxy basins. Climatic transposability will be tested for dry and wet years using Differential split-sample test. For incorporating both geographic and climatic transposability Proxy-basin differential split sample test will be used. For quantitative evaluation of SHM, during Split-sample test Nash-Sutcliffe efficiency (NSE), Coefficient of Determination (R R^2)) and Percent BIAS (PBIAS) are being used. However, for transposability, a productive approach involving these performance measures, i.e. NSE*R R^2)*PBIAS will be used to decide the best value of parameters. Keywords: SHM, credibility, operational testing, transposability.

  3. Algae viability over time in a ballast water sample

    NASA Astrophysics Data System (ADS)

    Gollasch, Stephan; David, Matej

    2018-03-01

    The biology of vessels' ballast water needs to be analysed for several reasons, one of these being performance tests of ballast water management systems. This analysis includes a viability assessment of phytoplankton. To overcome logistical problems to get algae sample processing gear on board of a vessel to document algae viability, samples may be transported to land-based laboratories. Concerns were raised how the storage conditions of the sample may impact algae viability over time and what the most appropriate storage conditions were. Here we answer these questions with a long-term algae viability study with daily sample analysis using Pulse-Amplitude Modulated (PAM) fluorometry. The sample was analysed over 79 days. We tested different storage conditions: fridge and room temperature with and without light. It seems that during the first two weeks of the experiment the viability remains almost unchanged with a slight downwards trend. In the continuing period, before the sample was split, a slightly stronger downwards viability trend was observed, which occurred at a similar rate towards the end of the experiment. After the sample was split, the strongest viability reduction was measured for the sample stored without light at room temperature. We concluded that the storage conditions, especially regarding temperature and light exposure, have a stronger impact on algae viability compared to the storage duration and that inappropriate storage conditions reduce algal viability. A sample storage time of up to two weeks in a dark and cool environment has little influence on the organism viability. This indicates that a two week time duration between sample taking on board a vessel and the viability measurement in a land-based laboratory may not be very critical.

  4. Resistance to vertical fracture of MTA-filled roots.

    PubMed

    EL-Ma'aita, Ahmad M; Qualtrough, Alison J E; Watts, David C

    2014-02-01

    To investigate the effect of MTA root canal fillings on the resistance to vertical root fracture (VRF) over different time intervals. Freshly extracted anterior human teeth with single canals and minimal curvatures were decoronated, instrumented to size 50/.05 ProTaper file, irrigated with 1%NaOCl and randomly allocated to one of three groups (n = 36): (i) filled with MTA, (ii) filled with gutta-percha and sealer and (iii) unfilled roots used as a negative control. Each group was subdivided into three subgroups (n = 12) according to the storage time of 48 h, 1 and 6 months at 37°C in synthetic tissue fluid (STF). Following the storage periods, filled roots were mounted in acrylic supports, and the periodontal ligament was simulated using elastomeric impression material. Vertical loading was carried out with a ball-ended steel cylinder fitted on a universal testing machine at 1 mm/min crosshead speed. The maximum force at fracture (F-max) and the fracture mode were recorded for each root. Data were statistically analysed using two-way anova and Bonferroni post hoc tests. The mean F-max was significantly higher in the MTA subgroups after 1 and 6 months compared with all other subgroups. Two modes of fracture were identified: split and comminuted. The mean F-max values recorded with the latter were significantly higher compared with the former (P < 0.001). In all groups, split fracture was the most dominant mode apart from the MTA/1 month and MTA/6 month groups. MTA increases the resistance to VRF of endodontically treated teeth and influences the mode of fracture after 1 and 6 month of storage in STF compared with gutta-percha and sealer. © 2013 John Wiley & Sons A/S.

  5. Visualization of retinal vascular structure and perfusion with a nonconfocal adaptive optics scanning light ophthalmoscope

    PubMed Central

    Sulai, Yusufu N.; Scoles, Drew; Harvey, Zachary; Dubra, Alfredo

    2015-01-01

    Imaging of the retinal vascular structure and perfusion was explored by confocal illumination and nonconfocal detection in an adaptive optics scanning light ophthalmoscope (AOSLO), as an extension of the work by Chui et al. [Biomed. Opt. Express 3, 2537 (2012)]. Five different detection schemes were evaluated at multiple retinal locations: circular mask, annular mask, circular mask with filament, knife-edge, and split-detector. Given the superior image contrast in the reflectance and perfusion maps, the split-detection method was further tested using pupil apodization, polarized detection, and four different wavelengths. None of these variations provided noticeable contrast improvement. The noninvasive visualization of capillary flow and structure provided by AOSLO split-detection shows great promise for studying ocular and systemic conditions that affect the retinal vasculature. PMID:24690655

  6. Effect of fly ash on the strength of porous concrete using recycled coarse aggregate to replace low-quality natural coarse aggregate

    NASA Astrophysics Data System (ADS)

    Arifi, Eva; Cahya, Evi Nur; Christin Remayanti, N.

    2017-09-01

    The performance of porous concrete made of recycled coarse aggregate was investigated. Fly ash was used as cement partial replacement. In this study, the strength of recycled aggregate was coMPared to low quality natural coarse aggregate which has high water absorption. Compression strength and tensile splitting strength test were conducted to evaluate the performance of porous concrete using fly ash as cement replacement. Results have shown that the utilization of recycled coarse aggregate up to 75% to replace low quality natural coarse aggregate with high water absorption increases compressive strength and splitting tensile strength of porous concrete. Using fly ash up to 25% as cement replacement improves compressive strength and splitting tensile strength of porous concrete.

  7. Splitting blood and blood product packaging reduces donor exposure for patients undergoing cardiopulmonary bypass.

    PubMed

    Nuszkowski, M M; Jonas, R A; Zurakowski, D; Deutsch, N

    2015-11-01

    Cardiopulmonary bypass for congenital heart surgery requires packed red cells (PRBC) and fresh frozen plasma (FFP) to be available, both for priming of the circuit as well as to replace blood loss. This study examines the hypothesis that splitting one unit of packed red blood cells and one unit of fresh frozen plasma into two half units reduces blood product exposure and wastage in the Operating Room. Beginning August 2013, the blood bank at Children's National Medical Center began splitting one unit of packed red blood cells (PRBC) and one unit of fresh frozen plasma (FFP) for patients undergoing cardiopulmonary bypass (CPB). The 283 patients who utilized CPB during calendar year 2013 were divided into 2 study groups: before the split and after the split. The principal endpoints were blood product usage and donor exposure intra-operatively and within 72 hours post-operatively. There was a significant decrease in median total donor exposures for FFP and cryoprecipitate from 5 to 4 per case (p = 0.007, Mann-Whitney U-test). However, there was no difference in the volume of blood and blood products used; in fact, there was a significant increase in the amount of FFP that was wasted with the switch to splitting the unit of FFP. We found that modification of blood product packaging can decrease donor exposure. Future investigation is needed as to how to modify packaging to minimize wastage. © The Author(s) 2015.

  8. Oriented covalent immobilization of antibodies for measurement of intermolecular binding forces between zipper-like contact surfaces of split inteins.

    PubMed

    Sorci, Mirco; Dassa, Bareket; Liu, Hongwei; Anand, Gaurav; Dutta, Amit K; Pietrokovski, Shmuel; Belfort, Marlene; Belfort, Georges

    2013-06-18

    In order to measure the intermolecular binding forces between two halves (or partners) of naturally split protein splicing elements called inteins, a novel thiol-hydrazide linker was designed and used to orient immobilized antibodies specific for each partner. Activation of the surfaces was achieved in one step, allowing direct intermolecular force measurement of the binding of the two partners of the split intein (called protein trans-splicing). Through this binding process, a whole functional intein is formed resulting in subsequent splicing. Atomic force microscopy (AFM) was used to directly measure the split intein partner binding at 1 μm/s between native (wild-type) and mixed pairs of C- and N-terminal partners of naturally occurring split inteins from three cyanobacteria. Native and mixed pairs exhibit similar binding forces within the error of the measurement technique (~52 pN). Bioinformatic sequence analysis and computational structural analysis discovered a zipper-like contact between the two partners with electrostatic and nonpolar attraction between multiple aligned ion pairs and hydrophobic residues. Also, we tested the Jarzynski's equality and demonstrated, as expected, that nonequilibrium dissipative measurements obtained here gave larger energies of interaction as compared with those for equilibrium. Hence, AFM coupled with our immobilization strategy and computational studies provides a useful analytical tool for the direct measurement of intermolecular association of split inteins and could be extended to any interacting protein pair.

  9. Nitrous oxide emission from wetland soil following single and seasonal split application of cattle manure to field tomato (Lycopersicon esculentum, Mill var. Heinz) and rape (Brassica napus, L. var. Giant) crops.

    PubMed

    Masaka, Johnson; Nyamangara, Justice; Wuta, Menas

    2016-01-01

    An understanding of the contribution of manure applications to global atmospheric N2O loading is needed to evaluate agriculture's contribution to the global warming process. Two field experiments were carried out at Dufuya wetland (19°17'S; 29°21'E, 1260 m above sea level) to determine the effects of single and split manure applications on emissions of N2O from soil during the growing seasons of two rape and two tomato crops. Two field experiments were established. In the first experiment the manure was applied in three levels of 0, 15, and 30 Mg ha(-1) as a single application just before planting of the first tomato crop. In the second experiment the 15 and 30 Mg ha(-1) manure application rates were divided into four split applications of 3.75 and 7.5 Mg ha(-1) respectively, for each of the four cropping events. Single applications of 15 and 30 Mg ha(-1) manure once in four cropping events had higher emissions of N2O than those recorded on plots that received split applications of 3.75 and 7.5 Mg ha(-1) manure at least up to the second test crop. Thereafter N2O emissions on plots subjected to split applications of manure were higher or equal to those recorded in plots that received single basal applications of 30 Mg ha(-1) applied a week before planting the first crop. Seasonal split applications of manure to wetland vegetable crops can reduce emissions of N2O at least up to the second seasonal split application.

  10. Factor Structure of the Revised TOEIC[R] Test: A Multiple-Sample Analysis

    ERIC Educational Resources Information Center

    In'nami, Yo; Koizumi, Rie

    2012-01-01

    This study examined the factor structure of the listening and reading sections of the revised Test of English for International Communication (TOEIC[R]) test. The data from the TOEIC IP (institutional program) test taken by 569 English learners were randomly split into two samples (n = 285 vs. 284). Four models (higher-order, correlated,…

  11. Influence of detector noise and background noise on detection-system

    NASA Astrophysics Data System (ADS)

    Song, Yiheng; Wang, Zhiyong

    2018-02-01

    Study the noise by detectors and background light ,we find that the influence of background noise on the detection is more than that of itself. Therefore, base on the fiber coupled beam splitting technique, the small area detector is used to replace the large area detector. It can achieve high signal-to-noise ratio (SNR) and reduce the speckle interference of the background light. This technique is expected to solve the bottleneck of large field of view and high sensitivity.

  12. Anisotropy beneath the Southern Pacific - real or apparent?

    NASA Astrophysics Data System (ADS)

    Prasse, Philipp; Thomas, Christine

    2016-04-01

    Anisotropy of the lowermost mantle beneath the South- to Central Pacific is investigated using US-Array receivers and events located near the Tonga-Fiji subduction zones. Differential splitting in three different distance ranges (65° -85° , 90° -110° and >110°) of S-ScS, SKS-S, SKS-Sdiff phases is used. By utilizing differential splitting technique, it was possible to correct for upper mantle, as well as source- and receiver side anisotropy and effectively quantify shear wave splitting originating in the lowermost mantle. Delay times of horizontal (SH) and vertical polarized (SV) shear waves show that predominantly the SH wave is delayed relative to the SV wave. Motivated by the discrepancy in previous Pacific studies investigating the lowermost mantle beneath the Pacific the possibility of isotropic structure producing the observed splitting is tested. Synthetic seismograms are computed, based on various isotropic models and the resulting synthetics are analysed in the same way as the real data. While simple layered models do not produce splitting and therefore apparent anisotropy, models in which the lowermost mantle is represented as a negative gradient in P- and S-wave velocity, produce clear apparent anisotropy. Thus, this study presents a possible alternative way of explaining the structure of the D" region.

  13. Moral judgement by the disconnected left and right cerebral hemispheres: a split-brain investigation.

    PubMed

    Steckler, Conor M; Hamlin, J Kiley; Miller, Michael B; King, Danielle; Kingstone, Alan

    2017-07-01

    Owing to the hemispheric isolation resulting from a severed corpus callosum, research on split-brain patients can help elucidate the brain regions necessary and sufficient for moral judgement. Notably, typically developing adults heavily weight the intentions underlying others' moral actions, placing greater importance on valenced intentions versus outcomes when assigning praise and blame. Prioritization of intent in moral judgements may depend on neural activity in the right hemisphere's temporoparietal junction, an area implicated in reasoning about mental states. To date, split-brain research has found that the right hemisphere is necessary for intent-based moral judgement. When testing the left hemisphere using linguistically based moral vignettes, split-brain patients evaluate actions based on outcomes, not intentions. Because the right hemisphere has limited language ability relative to the left, and morality paradigms to date have involved significant linguistic demands, it is currently unknown whether the right hemisphere alone generates intent-based judgements. Here we use nonlinguistic morality plays with split-brain patient J.W. to examine the moral judgements of the disconnected right hemisphere, demonstrating a clear focus on intent. This finding indicates that the right hemisphere is not only necessary but also sufficient for intent-based moral judgement, advancing research into the neural systems supporting the moral sense.

  14. Influences of strain rate on yield strength aluminum alloys

    NASA Astrophysics Data System (ADS)

    Rizal, Samsul; Firdaus, Hamdani Teuku; Thaib, Razali; Homma, Hiroomi

    2005-04-01

    The simulation of aircraft has often been performing by implementing finite element code on supercomputers. The reliability an accuracy of simulation depends mainly on the material model as well as on structural model used in calculations. Consequently, an accurate knowledge of mechanical behavior of materials under impact loading is essential for safety performance evaluation of structure. Impact tension tests on specimens for aircrafts and automotive structural applications are conduct by means of the split Hopkinson bar apparatus. Small specimens having diameter 4 mm are use in the test. Tensile stress-strain relations at strain rates of 102 s-1 to over 103 s-1 are present and compared with those obtained at quasi-static strain rates. The limitations on the applicability of apparatus are also discusses. The other importance of the reference of strain, while studying void growth in elastic-viscoplastic material, is emphasized. In the present paper, a simplified plane-symmetrical two-dimensional finite element model for a SHPB with a plate specimen made of an elastic material is first established. The used of strain gage mounted at the specimens to be monitored strain during the course of impact test. Comparisons may then be made between the numerical predicted and experimentally observed of load and a specimen strain. This report also describes the apparatus and instrumentation, and also be discusses the advantages and limitations of experimental technique. Fractograph is taken by scanning electron microscope on the center of the specimens for judgment of the fracture mechanism and strain rates influences on the materials.

  15. Quasi-particle spectrum in trilayer graphene: Role of onsite coulomb interaction and interlayer coupling

    NASA Astrophysics Data System (ADS)

    Kumar, Sanjay; Ajay

    2015-01-01

    Stacking dependent quasi-particle spectrum and density of states (DOS) in trilayer (ABC-, ABA- and AAA-stacked) graphene are analyzed using mean-field Green's function equations of motion method. Interlayer coupling (t1) is found to be responsible for the splitting of quasi-particle peaks in each stacking order. Coulomb interaction suppresses the trilayer splitting and generates a finite gap at Fermi level in ABC- while a tiny gap in ABA-stacked trilayer graphene. Influence of t⊥ is prominent for AAA-stacking as compared to ABC- and ABA-stacking orders. The theoretically obtained quasi-particle energies and DOS has been viewed in terms of recent angle resolved photoemission spectroscopic (ARPES) and scanning tunneling microscopic (STM) data available on these systems.

  16. Flow splitting in numerical simulations of oceanic dense-water outflows

    NASA Astrophysics Data System (ADS)

    Marques, Gustavo M.; Wells, Mathew G.; Padman, Laurie; Özgökmen, Tamay M.

    2017-05-01

    Flow splitting occurs when part of a gravity current becomes neutrally buoyant and separates from the bottom-trapped plume as an interflow. This phenomenon has been previously observed in laboratory experiments, small-scale water bodies (e.g., lakes) and numerical studies of small-scale systems. Here, the potential for flow splitting in oceanic gravity currents is investigated using high-resolution (Δx = Δz = 5 m) two-dimensional numerical simulations of gravity flows into linearly stratified environments. The model is configured to solve the non-hydrostatic Boussinesq equations without rotation. A set of experiments is conducted by varying the initial buoyancy number B0 =Q0N3 /g‧2 (where Q0 is the volume flux of the dense water flow per unit width, N is the ambient stratification and g‧ is the reduced gravity), the bottom slope (α) and the turbulent Prandtl number (Pr). Regardless of α or Pr, when B0 ≤ 0.002 the outflow always reaches the deep ocean forming an underflow. Similarly, when B0 ≥ 0.13 the outflow always equilibrates at intermediate depths, forming an interflow. However, when B0 ∼ 0.016, flow splitting always occurs when Pr ≥ 10, while interflows always occur for Pr = 1. An important characteristic of simulations that result in flow splitting is the development of Holmboe-like interfacial instabilities and flow transition from a supercritical condition, where the Froude number (Fr) is greater than one, to a slower and more uniform subcritical condition (Fr < 1). This transition is associated with an internal hydraulic jump and consequent mixing enhancement. Although our experiments do not take into account three-dimensionality and rotation, which are likely to influence mixing and the transition between flow regimes, a comparison between our results and oceanic observations suggests that flow splitting may occur in dense-water outflows with weak ambient stratification, such as Antarctic outflows.

  17. Dynamic Fracture Behavior of Plastic-Bonded Explosives

    NASA Astrophysics Data System (ADS)

    Fu, Hua; Li, Jun-Ling; Tan, Duo-Wang; Ifp, Caep Team

    2011-06-01

    Plastic-Bonded Explosives (PBX) are used as important energetic materials in nuclear or conventional weapons. Arms Warhead in the service process and the ballistic phase, may experience complex process such as long pulse and higher loading, compresson, tension and reciprocating compression - tension, friction with the projectile shell, which would lead to explosive deformation and fracture.And the dynamic deformation and fracture behavior of PBX subsequently affect reaction characteristics and initiation mechanism in explosives, then having influence on explosives safety. The dynamic fracure behavior of PBX are generally complex and not well studied or understood. In this paper, the dynamic fracture of explosives are conducted using a Kolsky bar. The Brazilian test, also known as a indirect tensile test or splitting test, is chosen as the test method. Tensile strength under different strain rates are obtained using quartz crystal embedded in rod end. The dynamic deformation and fracture process are captured in real-time by high-speed digital camera, and the displacement and strain fields distribution before specimen fracture are obtained by digital correlation method. Considering the non-uniform microstructure of explosives,the dynamic fracture behavior of explosive are simulated by discrete element method, the simulation results can reproduce the deformation and fracture process in Brazilian test using a maximum tensile strain criterion.

  18. Convergence of separate orbits for enhanced thermoelectric performance of layered ZrS2

    NASA Astrophysics Data System (ADS)

    Ding, Guangqian; Chen, Jinfeng; Yao, Kailun; Gao, Guoying

    2017-07-01

    Minimizing the band splitting energy to approach orbital degeneracy has been shown as a route to improved thermoelectric performance. This represents an open opportunity in some promising layered materials where there is a separation of p orbitals at the valence band edge due to the crystal field splitting. In this work, using ab initio calculations and semiclassical Boltzmann transport theory, we try to figure out how orbital degeneracy influences the thermoelectric properties of layered transition-metal dichalcogenide ZrS2. We tune the splitting energy by applying compressive biaxial strain, and find out that near-degeneration at the {{Γ }} point can be achieved for around 3% strain. As expected, the enhanced density-of-states effective mass results in an increased power factor. Interestingly, we also find a marked decline in the lattice thermal conductivity due to the effect of strain on phonon velocities and scattering. The two effects synergetically enhance the figure of merit. Our results highlight the convenience of exploring this optimization route in layered thermoelectric materials with band structures similar to that of ZrS2.

  19. Use of an Electrochemical Split Cell Technique to Evaluate the Influence of Shewanella oneidensis Activities on Corrosion of Carbon Steel.

    PubMed

    Miller, Robert Bertram; Sadek, Anwar; Rodriguez, Alvaro; Iannuzzi, Mariano; Giai, Carla; Senko, John M; Monty, Chelsea N

    2016-01-01

    Microbially induced corrosion (MIC) is a complex problem that affects various industries. Several techniques have been developed to monitor corrosion and elucidate corrosion mechanisms, including microbiological processes that induce metal deterioration. We used zero resistance ammetry (ZRA) in a split chamber configuration to evaluate the effects of the facultatively anaerobic Fe(III) reducing bacterium Shewanella oneidensis MR-1 on the corrosion of UNS G10180 carbon steel. We show that activities of S. oneidensis inhibit corrosion of steel with which that organism has direct contact. However, when a carbon steel coupon in contact with S. oneidensis was electrically connected to a second coupon that was free of biofilm (in separate chambers of the split chamber assembly), ZRA-based measurements indicated that current moved from the S. oneidensis-containing chamber to the cell-free chamber. This electron transfer enhanced the O2 reduction reaction on the coupon deployed in the cell free chamber, and consequently, enhanced oxidation and corrosion of that electrode. Our results illustrate a novel mechanism for MIC in cases where metal surfaces are heterogeneously covered by biofilms.

  20. Spectroscopic studies of two spectral variants of light-harvesting complex 2 (LH2) from the photosynthetic purple sulfur bacterium Allochromatium vinosum.

    PubMed

    Niedzwiedzki, Dariusz M; Bina, David; Picken, Nichola; Honkanen, Suvi; Blankenship, Robert E; Holten, Dewey; Cogdell, Richard J

    2012-09-01

    Two spectral forms of the peripheral light-harvesting complex (LH2) from the purple sulfur photosynthetic bacterium Allochromatium vinosum were purified and their photophysical properties characterized. The complexes contain bacteriochlorophyll a (BChl a) and multiple species of carotenoids. The composition of carotenoids depends on the light conditions applied during growth of the cultures. In addition, LH2 grown under high light has a noticeable split of the B800 absorption band. The influence of the change of carotenoid distribution as well as the spectral change of the excitonic absorption of the bacteriochlorophylls on the light-harvesting ability was studied using steady-state absorption, fluorescence and femtosecond time-resolved absorption at 77K. The results demonstrate that the change of the distribution of the carotenoids when cells were grown at low light adapts the absorptive properties of the complex to the light conditions and maintains maximum photon-capture performance. In addition, an explanation for the origin of the enigmatic split of the B800 absorption band is provided. This spectral splitting is also observed in LH2 complexes from other photosynthetic sulfur purple bacterial species. According to results obtained from transient absorption spectroscopy, the B800 band split originates from two spectral forms of the associated BChl a monomeric molecules bound within the same complex. Copyright © 2012 Elsevier B.V. All rights reserved.

  1. Ab initio assessment of Bi1-xRExCuOS (RE = La, Gd, Y, Lu) solid solutions as a semiconductor for photochemical water splitting.

    PubMed

    Lardhi, Sheikha; Curutchet, Antton; Cavallo, Luigi; Harb, Moussab; Le Bahers, Tangui

    2017-05-17

    The investigation of the BiCuOCh (Ch = S, Se and Te) semiconductor family for thermoelectric or photovoltaic materials is a topic of increasing research interest. These materials can also be considered for photochemical water splitting if one representative having a bandgap, E g , at around 2 eV can be developed. With this aim, we simulated the solid solutions Bi 1-x RE x CuOS (RE = Y, La, Gd and Lu) from pure BiCuOS (E g ∼ 1.1 eV) to pure RECuOS compositions (E g ∼ 2.9 eV) by DFT calculations based on the HSE06 range-separated hybrid functional with the inclusion of spin-orbit coupling. Starting from the thermodynamic stability of the solid solution, several properties were computed for each system including bandgaps, dielectric constants, effective masses and exciton binding energies. We discussed the variation of these properties based on the relative organization of Bi and RE atoms in their common sublattice to offer a physical understanding of the influence of the RE doping of BiCuOS. Some compositions were found to give appropriate properties for water splitting applications. Furthermore, we found that at low RE fractions the transport properties of BiCuOS are improved that can find applications beyond water splitting.

  2. Representativeness of laboratory sampling procedures for the analysis of trace metals in soil.

    PubMed

    Dubé, Jean-Sébastien; Boudreault, Jean-Philippe; Bost, Régis; Sona, Mirela; Duhaime, François; Éthier, Yannic

    2015-08-01

    This study was conducted to assess the representativeness of laboratory sampling protocols for purposes of trace metal analysis in soil. Five laboratory protocols were compared, including conventional grab sampling, to assess the influence of sectorial splitting, sieving, and grinding on measured trace metal concentrations and their variability. It was concluded that grinding was the most important factor in controlling the variability of trace metal concentrations. Grinding increased the reproducibility of sample mass reduction by rotary sectorial splitting by up to two orders of magnitude. Combined with rotary sectorial splitting, grinding increased the reproducibility of trace metal concentrations by almost three orders of magnitude compared to grab sampling. Moreover, results showed that if grinding is used as part of a mass reduction protocol by sectorial splitting, the effect of sieving on reproducibility became insignificant. Gy's sampling theory and practice was also used to analyze the aforementioned sampling protocols. While the theoretical relative variances calculated for each sampling protocol qualitatively agreed with the experimental variances, their quantitative agreement was very poor. It was assumed that the parameters used in the calculation of theoretical sampling variances may not correctly estimate the constitutional heterogeneity of soils or soil-like materials. Finally, the results have highlighted the pitfalls of grab sampling, namely, the fact that it does not exert control over incorrect sampling errors and that it is strongly affected by distribution heterogeneity.

  3. One-dimensional high-order compact method for solving Euler's equations

    NASA Astrophysics Data System (ADS)

    Mohamad, M. A. H.; Basri, S.; Basuno, B.

    2012-06-01

    In the field of computational fluid dynamics, many numerical algorithms have been developed to simulate inviscid, compressible flows problems. Among those most famous and relevant are based on flux vector splitting and Godunov-type schemes. Previously, this system was developed through computational studies by Mawlood [1]. However the new test cases for compressible flows, the shock tube problems namely the receding flow and shock waves were not investigated before by Mawlood [1]. Thus, the objective of this study is to develop a high-order compact (HOC) finite difference solver for onedimensional Euler equation. Before developing the solver, a detailed investigation was conducted to assess the performance of the basic third-order compact central discretization schemes. Spatial discretization of the Euler equation is based on flux-vector splitting. From this observation, discretization of the convective flux terms of the Euler equation is based on a hybrid flux-vector splitting, known as the advection upstream splitting method (AUSM) scheme which combines the accuracy of flux-difference splitting and the robustness of flux-vector splitting. The AUSM scheme is based on the third-order compact scheme to the approximate finite difference equation was completely analyzed consequently. In one-dimensional problem for the first order schemes, an explicit method is adopted by using time integration method. In addition to that, development and modification of source code for the one-dimensional flow is validated with four test cases namely, unsteady shock tube, quasi-one-dimensional supersonic-subsonic nozzle flow, receding flow and shock waves in shock tubes. From these results, it was also carried out to ensure that the definition of Riemann problem can be identified. Further analysis had also been done in comparing the characteristic of AUSM scheme against experimental results, obtained from previous works and also comparative analysis with computational results generated by van Leer, KFVS and AUSMPW schemes. Furthermore, there is a remarkable improvement with the extension of the AUSM scheme from first-order to third-order accuracy in terms of shocks, contact discontinuities and rarefaction waves.

  4. Dual-Use Partnership Addresses Performance Problems with "Y" Pattern Control Valves

    NASA Technical Reports Server (NTRS)

    Bailey, John W.

    2004-01-01

    A Dual-Use Cooperative Agreement between the Propulsion Test Directorate (PTD) at Stennis Space Center (SSC) and Oceaneering Reflange, Inc. of Houston, TX has produced an improved 'Y' pattern split-body control valve for use in the propulsion test facilities at Stennis Space Center. The split-body, or clamped bonnet technology, provides for a 'cleaner' valve design featuring enhanced performance and increased flow capacity with extended life expectancy. Other points addressed by the partnership include size, weight and costs. Overall size and weight of each valve will be reduced by 50% compared to valves currently in use at SSC. An initial procurement of two 10 inch valves will result in an overall cost reduction of 15% or approximately $50,000 per valve.

  5. QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.

    PubMed

    Toropov, Andrey A; Toropova, Alla P; Raska, Ivan; Benfenati, Emilio

    2010-04-01

    Three different splits into the subtraining set (n = 22), the set of calibration (n = 21), and the test set (n = 12) of 55 antineoplastic agents have been examined. By the correlation balance of SMILES-based optimal descriptors quite satisfactory models for the octanol/water partition coefficient have been obtained on all three splits. The correlation balance is the optimization of a one-variable model with a target function that provides both the maximal values of the correlation coefficient for the subtraining and calibration set and the minimum of the difference between the above-mentioned correlation coefficients. Thus, the calibration set is a preliminary test set. Copyright (c) 2009 Elsevier Masson SAS. All rights reserved.

  6. Radiographic Evidence of Hip Microinstability in Elite Ballet.

    PubMed

    Mitchell, Ronald J; Gerrie, Brayden J; McCulloch, Patrick C; Murphy, Andrew J; Varner, Kevin E; Lintner, David M; Harris, Joshua D

    2016-06-01

    To determine prevalence, magnitude, and predisposing radiographic features of hip subluxation in elite ballet dancers. A cross-sectional investigation of professional male and female ballet dancers was performed using 5 plain radiographs. A "splits" anteroposterior (AP) radiograph was performed with legs abducted parallel to the trunk in the coronal plane (splits position; grand écart facial). Hip center position (HCP) was measured on standing AP pelvis and AP pelvis splits views and the difference calculated (subluxation distance) to determine prevalence and magnitude of femoral head subluxation. Student t test compared HCP on AP pelvis and splits radiographs. Pearson correlations were used to correlate splits HCP with radiographic measures of femoroacetabular impingement and dysplasia. Analyzing 47 dancers (21 men, 26 women; 23.8 ± 5.4 years), mean HCP on standing AP pelvis was 9.39 ± 3.33 mm versus 10.8 ± 2.92 mm on splits radiograph, with mean subluxation distance of 1.41 mm (P = .035). Forty-two dancers' femoral heads translated laterally with splits positioning, and 17 dancers (36%) exhibited a "vacuum sign" (bilateral in 71% of subjects with at least 1 hip vacuum sign). There was strong positive correlation (r = 0.461, P = .001) with splits HCP and alpha angle (Dunn 45°), and moderate negative correlation (r = -0.332, P = .022) with subluxation distance and neck-shaft angle. In men, splits HCP increased as lateral center edge angle (CEA) decreased (r = -0.437, P = .047), as anterior CEA decreased (r = -0.482, P = .027), as Tönnis angle increased (r = 0.656, P = .001), and as femoral head extrusion index increased (r = 0.511, P = .018). In women, there was moderate negative correlation (r = -0.389, P = .049) with subluxation distance and neck-shaft angle. Hip subluxation occurs during splits in most professional ballet dancers, with a significantly greater magnitude of subluxation in women than men. Subluxation magnitude increases with increasing alpha angle and decreasing neck-shaft angle. In men, the magnitude increases with severity of dysplasia. Women had subluxation regardless of acetabular morphology but increased subluxation with decreased neck-shaft angle. This provides radiographic support for hip microinstability in elite ballet. Level IV, diagnostic. Copyright © 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  7. 75 FR 25224 - Energy Conservation Program for Commercial Equipment: Decision and Order Granting a Waiver to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... systems. As a condition of this waiver, Daikin must use the alternate test procedure set forth in this... systems contain design characteristics that prevent them from being tested using the current DOE test.... The VRV-III-C systems have operational characteristics similar to other commercial multi-split...

  8. Small scale noise and wind tunnel tests of upper surface blowing nozzle flap concepts. Volume 1. Aerodynamic test results

    NASA Technical Reports Server (NTRS)

    Renselaer, D. J.; Nishida, R. S.; Wilkin, C. A.

    1975-01-01

    The results and analyses of aerodynamic and acoustic studies conducted on the small scale noise and wind tunnel tests of upper surface blowing nozzle flap concepts are presented. Various types of nozzle flap concepts were tested. These are an upper surface blowing concept with a multiple slot arrangement with seven slots (seven slotted nozzle), an upper surface blowing type with a large nozzle exit at approximately mid-chord location in conjunction with a powered trailing edge flap with multiple slots (split flow or partially slotted nozzle). In addition, aerodynamic tests were continued on a similar multi-slotted nozzle flap, but with 14 slots. All three types of nozzle flap concepts tested appear to be about equal in overall aerodynamic performance but with the split flow nozzle somewhat better than the other two nozzle flaps in the landing approach mode. All nozzle flaps can be deflected to a large angle to increase drag without significant loss in lift. The nozzle flap concepts appear to be viable aerodynamic drag modulation devices for landing.

  9. Corn nitrogen management influences nitrous oxide emissions in drained and undrained soils

    USDA-ARS?s Scientific Manuscript database

    Tile-drainage and nitrogen (N) fertilization are important for corn (Zea mays L.) production. To date, no studies have evaluated nitrous oxide (N2O) emissions of single vs. split-N fertilizer application under different soil drainage conditions. The objective of this study was to quantify season-lon...

  10. Effects of Communication Tasks on the Grammatical Relations Marked by Second Language Learners.

    ERIC Educational Resources Information Center

    Newton, Jonathan; Kennedy, Graeme

    1996-01-01

    Examines the morpho-syntax of task-based interaction and reports some possible grammatical consequences of interaction in split and shared information tasks undertaken by adult second language learners of English. Results indicate that communication tasks for language learning can be designed to influence the use of particular linguistic…

  11. Discriminative and Criterion Validity of the Autism Spectrum Identity Scale (ASIS)

    ERIC Educational Resources Information Center

    McDonald, T. A. M.

    2017-01-01

    Individuals on the autism spectrum face stigma that can influence identity development. Previous research on the 22-item Autism Spectrum Identity Scale (ASIS) reported a four-factor structure with strong split-sample cross-validation and good internal consistency. This study reports the discriminative and criterion validity of the ASIS with other…

  12. Protein from Meat or Vegetable Sources in Meals Matched for Fiber Content has Similar Effects on Subjective Appetite Sensations and Energy Intake-A Randomized Acute Cross-Over Meal Test Study.

    PubMed

    Nielsen, Lone V; Kristensen, Marlene D; Klingenberg, Lars; Ritz, Christian; Belza, Anita; Astrup, Arne; Raben, Anne

    2018-01-16

    Higher-protein meals decrease hunger and increase satiety compared to lower-protein meals. However, no consensus exists about the different effects of animal and vegetable proteins on appetite. We investigated how a meal based on vegetable protein (fava beans/split peas) affected ad libitum energy intake and appetite sensations, compared to macronutrient-balanced, iso-caloric meals based on animal protein (veal/pork or eggs). Thirty-five healthy men were enrolled in this acute cross-over study. On each test day, participants were presented with one of four test meals (~3550 kilojoules (kJ) 19% of energy from protein), based on fava beans/split peas (28.5 g fiber), pork/veal or eggs supplemented with pea fiber to control for fiber content (28.5 g fiber), or eggs without supplementation of fiber (6.0 g fiber). Subjective appetite sensations were recorded at baseline and every half hour until the ad libitum meal three hours later. There were no differences in ad libitum energy intake across test meals ( p > 0.05). Further, no differences were found across meals for hunger, satiety, fullness, prospective food consumption, or composite appetite score (all p > 0.05). Iso-caloric, macronutrient-balanced, fiber-matched meals based on vegetable protein (fava beans/split peas) or animal protein (veal/pork or eggs) had similar effects on ad libitum energy intake and appetite sensations.

  13. Protein from Meat or Vegetable Sources in Meals Matched for Fiber Content has Similar Effects on Subjective Appetite Sensations and Energy Intake—A Randomized Acute Cross-Over Meal Test Study

    PubMed Central

    Nielsen, Lone V.; Kristensen, Marlene D.; Klingenberg, Lars; Belza, Anita

    2018-01-01

    Higher-protein meals decrease hunger and increase satiety compared to lower-protein meals. However, no consensus exists about the different effects of animal and vegetable proteins on appetite. We investigated how a meal based on vegetable protein (fava beans/split peas) affected ad libitum energy intake and appetite sensations, compared to macronutrient-balanced, iso-caloric meals based on animal protein (veal/pork or eggs). Thirty-five healthy men were enrolled in this acute cross-over study. On each test day, participants were presented with one of four test meals (~3550 kilojoules (kJ) 19% of energy from protein), based on fava beans/split peas (28.5 g fiber), pork/veal or eggs supplemented with pea fiber to control for fiber content (28.5 g fiber), or eggs without supplementation of fiber (6.0 g fiber). Subjective appetite sensations were recorded at baseline and every half hour until the ad libitum meal three hours later. There were no differences in ad libitum energy intake across test meals (p > 0.05). Further, no differences were found across meals for hunger, satiety, fullness, prospective food consumption, or composite appetite score (all p > 0.05). Iso-caloric, macronutrient-balanced, fiber-matched meals based on vegetable protein (fava beans/split peas) or animal protein (veal/pork or eggs) had similar effects on ad libitum energy intake and appetite sensations. PMID:29337861

  14. Analysis of a Split-Plot Experimental Design Applied to a Low-Speed Wind Tunnel Investigation

    NASA Technical Reports Server (NTRS)

    Erickson, Gary E.

    2013-01-01

    A procedure to analyze a split-plot experimental design featuring two input factors, two levels of randomization, and two error structures in a low-speed wind tunnel investigation of a small-scale model of a fighter airplane configuration is described in this report. Standard commercially-available statistical software was used to analyze the test results obtained in a randomization-restricted environment often encountered in wind tunnel testing. The input factors were differential horizontal stabilizer incidence and the angle of attack. The response variables were the aerodynamic coefficients of lift, drag, and pitching moment. Using split-plot terminology, the whole plot, or difficult-to-change, factor was the differential horizontal stabilizer incidence, and the subplot, or easy-to-change, factor was the angle of attack. The whole plot and subplot factors were both tested at three levels. Degrees of freedom for the whole plot error were provided by replication in the form of three blocks, or replicates, which were intended to simulate three consecutive days of wind tunnel facility operation. The analysis was conducted in three stages, which yielded the estimated mean squares, multiple regression function coefficients, and corresponding tests of significance for all individual terms at the whole plot and subplot levels for the three aerodynamic response variables. The estimated regression functions included main effects and two-factor interaction for the lift coefficient, main effects, two-factor interaction, and quadratic effects for the drag coefficient, and only main effects for the pitching moment coefficient.

  15. Characterization of Damage in Triaxial Braid Composites Under Tensile Loading

    NASA Technical Reports Server (NTRS)

    Littell, Justin D.; Binienda, Wieslaw K.; Roberts, Gary D.; Goldberg, Robert K.

    2009-01-01

    Carbon fiber composites utilizing flattened, large tow yarns in woven or braided forms are being used in many aerospace applications. Their complex fiber architecture and large unit cell size present challenges in both understanding deformation processes and measuring reliable material properties. This report examines composites made using flattened 12k and 24k standard modulus carbon fiber yarns in a 0 /+60 /-60 triaxial braid architecture. Standard straight-sided tensile coupons are tested with the 0 axial braid fibers either parallel with or perpendicular to the applied tensile load (axial or transverse tensile test, respectively). Nonuniform surface strain resulting from the triaxial braid architecture is examined using photogrammetry. Local regions of high strain concentration are examined to identify where failure initiates and to determine the local strain at the time of initiation. Splitting within fiber bundles is the first failure mode observed at low to intermediate strains. For axial tensile tests splitting is primarily in the 60 bias fibers, which were oriented 60 to the applied load. At higher strains, out-of-plane deformation associated with localized delamination between fiber bundles or damage within fiber bundles is observed. For transverse tensile tests, the splitting is primarily in the 0 axial fibers, which were oriented transverse to the applied load. The initiation and accumulation of local damage causes the global transverse stress-strain curves to become nonlinear and causes failure to occur at a reduced ultimate strain. Extensive delamination at the specimen edges is also observed.

  16. The cryptomnesic origins of Jung's dream of the multi-storeyed house.

    PubMed

    Myers, Steve

    2009-09-01

    Jung first recounted his dream of the multi-storeyed house in the 1925 seminars to illustrate the concept of the collective unconscious and explain the influence of phylogeny on his split with Freud. However, his telling the story of the dream belies a cryptomnesic influence of the early writings of psychoanalysis because Josef Breuer used a similar image to illustrate the structure of the psyche which Edouard Claparède associated with a phylogenetic inheritance. When telling the story of the dream, Jung misrepresented Freud's position, creating the impression of there being a bigger difference between their theories than was actually the case, and giving the dream a fictional significance for the breakdown of their relationship. In fact, Jung followed Freud into the fields of mythology and phylogenetics, and their split was due primarily to their different attitudes towards sexuality rather than phylogeny. The dream image has therefore led to a misunderstanding of Freudian theory when viewed from within a Jungian perspective. Freud believed there was a phylogenetic layer in the psyche, though he held a different view to Jung on its nature and importance.

  17. Effect of the use of combination uridine triphosphate, cytidine monophosphate, and hydroxycobalamin on the recovery of neurosensory disturbance after bilateral sagittal split osteotomy: a randomized, double-blind trial.

    PubMed

    Vieira, C L; Vasconcelos, B C do E; Leão, J C; Laureano Filho, J R

    2016-02-01

    The change in neurosensory lesions that develop after bilateral sagittal split osteotomy (BSSO) was explored, and the influence of the application of combination uridine triphosphate (UTP), cytidine monophosphate (CMP), and hydroxycobalamin (vitamin B12) on patient outcomes was assessed. This was a randomized, controlled, double-blind trial. The study sample comprised 12 patients, each evaluated on both sides (thus 24 sides). All patients fulfilled defined selection criteria. Changes in the lesions were measured both subjectively and objectively. The sample was divided into two patient groups: an experimental group receiving medication and a control group receiving placebo. The statistical analysis was performed using SPSS software. Lesions in both groups improved and no statistically significant difference between the groups was observed at any time. 'Severe' injuries in the experimental group were more likely to exhibit a significant improvement after 6 months. Based on the results of the present study, it is concluded that the combination UTP, CMP, and hydroxycobalamin did not influence recovery from neurosensory disorders. Copyright © 2015. Published by Elsevier Ltd.

  18. Characteristics of plasma plume in ultrafast laser ablation with a weakly ionized air channel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hou, Huaming; Yang, Bo; Mao, Xianglei

    We report the influence of femtosecond (fs) laser weakly ionized air channel on characteristics of plasma induced from fs-laser ablation of solid Zr metal target. A novel method to create high temperature, low electron density plasma with intense elemental emission and weak bremsstrahlung emission was demonstrated. Weakly ionized air channel was generated as a result of a non-linear phenomenon. Two-dimensional time-resolved optical-emission images of plasma plumes were taken for plume dynamics analysis. Dynamic physical properties of filament channels were simulated. In particular, we investigated the influence of weakly ionized air channel on the evolution of solid plasma plume. Plasma plumemore » splitting was observed whilst longer weakly ionized air channel formed above the ablation spot. The domination mechanism for splitting is attributed to the long-lived underdense channel created by fs-laser induced weakly ionization of air. The evolutions of atomic/molecular emission intensity, peak broadening, and plasma temperature were analyzed, and the results show that the part of plasma entering weakly ionized air channel features higher initial temperature, lower electron density and faster decay.« less

  19. Characteristics of plasma plume in ultrafast laser ablation with a weakly ionized air channel

    DOE PAGES

    Hou, Huaming; Yang, Bo; Mao, Xianglei; ...

    2018-05-10

    We report the influence of femtosecond (fs) laser weakly ionized air channel on characteristics of plasma induced from fs-laser ablation of solid Zr metal target. A novel method to create high temperature, low electron density plasma with intense elemental emission and weak bremsstrahlung emission was demonstrated. Weakly ionized air channel was generated as a result of a non-linear phenomenon. Two-dimensional time-resolved optical-emission images of plasma plumes were taken for plume dynamics analysis. Dynamic physical properties of filament channels were simulated. In particular, we investigated the influence of weakly ionized air channel on the evolution of solid plasma plume. Plasma plumemore » splitting was observed whilst longer weakly ionized air channel formed above the ablation spot. The domination mechanism for splitting is attributed to the long-lived underdense channel created by fs-laser induced weakly ionization of air. The evolutions of atomic/molecular emission intensity, peak broadening, and plasma temperature were analyzed, and the results show that the part of plasma entering weakly ionized air channel features higher initial temperature, lower electron density and faster decay.« less

  20. [The appraisal of reliability and validity of subjective workload assessment technique and NASA-task load index].

    PubMed

    Xiao, Yuan-mei; Wang, Zhi-ming; Wang, Mian-zhen; Lan, Ya-jia

    2005-06-01

    To test the reliability and validity of two mental workload assessment scales, i.e. subjective workload assessment technique (SWAT) and NASA task load index (NASA-TLX). One thousand two hundred and sixty-eight mental workers were sampled from various kinds of occupations, such as scientific research, education, administration and medicine, etc, with randomized cluster sampling. The re-test reliability, split-half reliability, Cronbach's alpha coefficient and correlation coefficients between item score and total score were adopted to test the reliability. The test of validity included structure validity. The re-test reliability coefficients of these two scales and their items were ranged from 0.516 to 0.753 (P < 0.01), indicating the two scales had good re-test reliability; the split-half reliability of SWAT was 0.645, and its Cronbach's alpha coefficient was more than 0.80, all the correlation coefficients between its items score and total score were more than 0.70; as for NASA-TLX, both the split-half reliability and Cronbach's alpha coefficient were more than 0.80, the correlation coefficients between its items score and total score were all more than 0.60 (P < 0.01) except the item of performance. Both scales had good inner consistency. The Pearson correlation coefficient between the two scales was 0.492 (P < 0.01), implying the results of the two scales had good consistency. Factor analysis showed that the two scales had good structure validity. Both SWAT and NASA-TLX have good reliability and validity and may be used as a valid tool to assess mental workload in China after being revised properly.

  1. Split Hopkinson resonant bar test for sonic-frequency acoustic velocity and attenuation measurements of small, isotropic geological samples.

    PubMed

    Nakagawa, Seiji

    2011-04-01

    Mechanical properties (seismic velocities and attenuation) of geological materials are often frequency dependent, which necessitates measurements of the properties at frequencies relevant to a problem at hand. Conventional acoustic resonant bar tests allow measuring seismic properties of rocks and sediments at sonic frequencies (several kilohertz) that are close to the frequencies employed for geophysical exploration of oil and gas resources. However, the tests require a long, slender sample, which is often difficult to obtain from the deep subsurface or from weak and fractured geological formations. In this paper, an alternative measurement technique to conventional resonant bar tests is presented. This technique uses only a small, jacketed rock or sediment core sample mediating a pair of long, metal extension bars with attached seismic source and receiver-the same geometry as the split Hopkinson pressure bar test for large-strain, dynamic impact experiments. Because of the length and mass added to the sample, the resonance frequency of the entire system can be lowered significantly, compared to the sample alone. The experiment can be conducted under elevated confining pressures up to tens of MPa and temperatures above 100 [ordinal indicator, masculine]C, and concurrently with x-ray CT imaging. The described split Hopkinson resonant bar test is applied in two steps. First, extension and torsion-mode resonance frequencies and attenuation of the entire system are measured. Next, numerical inversions for the complex Young's and shear moduli of the sample are performed. One particularly important step is the correction of the inverted Young's moduli for the effect of sample-rod interfaces. Examples of the application are given for homogeneous, isotropic polymer samples, and a natural rock sample. © 2011 American Institute of Physics

  2. The EEG Split Alpha Peak: Phenomenological Origins and Methodological Aspects of Detection and Evaluation.

    PubMed

    Olejarczyk, Elzbieta; Bogucki, Piotr; Sobieszek, Aleksander

    2017-01-01

    Electroencephalographic (EEG) patterns were analyzed in a group of ambulatory patients who ranged in age and sex using spectral analysis as well as Directed Transfer Function, a method used to evaluate functional brain connectivity. We tested the impact of window size and choice of reference electrode on the identification of two or more peaks with close frequencies in the spectral power distribution, so called "split alpha." Together with the connectivity analysis, examination of spatiotemporal maps showing the distribution of amplitudes of EEG patterns allowed for better explanation of the mechanisms underlying the generation of split alpha peaks. It was demonstrated that the split alpha spectrum can be generated by two or more independent and interconnected alpha wave generators located in different regions of the cerebral cortex, but not necessarily in the occipital cortex. We also demonstrated the importance of appropriate reference electrode choice during signal recording. In addition, results obtained using the original data were compared with results obtained using re-referenced data, using average reference electrode and reference electrode standardization techniques.

  3. Probing medium-induced jet splitting and energy loss in heavy-ion collisions

    NASA Astrophysics Data System (ADS)

    Chang, Ning-Bo; Cao, Shanshan; Qin, Guang-You

    2018-06-01

    The nuclear modification of jet splitting in relativistic heavy-ion collisions at RHIC and the LHC energies is studied based on the higher twist formalism. Assuming coherent energy loss for the two splitted subjets, a non-monotonic jet energy dependence is found for the nuclear modification of jet splitting function: strongest modification at intermediate jet energies whereas weaker modification for larger or smaller jet energies. Combined with the smaller size and lower density of the QGP medium at RHIC than at the LHC, this helps to understand the groomed jet measurements from CMS and STAR Collaborations: strong modification of the momentum sharing zg distribution at the LHC and no obvious modification of zg distribution at RHIC. In addition, the observed nuclear modification pattern of the groomed jet zg distribution cannot be explained solely by independent energy loss of the two subjets. Our result may be tested in future measurements of groomed jets with lower jet energies at the LHC and larger jet energies at RHIC, for different angular separations between the two subjets.

  4. Potential of human twin embryos generated by embryo splitting in assisted reproduction and research.

    PubMed

    Noli, Laila; Ogilvie, Caroline; Khalaf, Yacoub; Ilic, Dusko

    2017-03-01

    Embryo splitting or twinning has been widely used in veterinary medicine over 20 years to generate monozygotic twins with desirable genetic characteristics. The first human embryo splitting, reported in 1993, triggered fierce ethical debate on human embryo cloning. Since Dolly the sheep was born in 1997, the international community has acknowledged the complexity of the moral arguments related to this research and has expressed concerns about the potential for reproductive cloning in humans. A number of countries have formulated bans either through laws, decrees or official statements. However, in general, these laws specifically define cloning as an embryo that is generated via nuclear transfer (NT) and do not mention embryo splitting. Only the UK includes under cloning both embryo splitting and NT in the same legislation. On the contrary, the Ethics Committee of the American Society for Reproductive Medicine does not have a major ethical objection to transferring two or more artificially created embryos with the same genome with the aim of producing a single pregnancy, stating that 'since embryo splitting has the potential to improve the efficacy of IVF treatments for infertility, research to investigate the technique is ethically acceptable'. Embryo splitting has been introduced successfully to the veterinary medicine several decades ago and today is a part of standard practice. We present here an overview of embryo splitting experiments in humans and non-human primates and discuss the potential of this technology in assisted reproduction and research. A comprehensive literature search was carried out using PUBMED and Google Scholar databases to identify studies on embryo splitting in humans and non-human primates. 'Embryo splitting' and 'embryo twinning' were used as the keywords, alone or in combination with other search phrases relevant to the topics of biology of preimplantation embryos. A very limited number of studies have been conducted in humans and non-human primates. The published material, especially the studies with human embryos, is controversial. Some reports suggest that twinning technology will find clinical use in reproductive medicine in the future, whereas others conclude the opposite that human twin embryos created in vitro are unsuitable not only for clinical, but also for research, purposes. The blastomere biopsy technique of embryo splitting seems to be unsuitable for either clinical or research purposes; however, embryo bisection, a preferable method of cloning in veterinary medicine, has not yet been tested on human embryos. © The Author 2016. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  5. Influence of war on quantitative and qualitative changes in drug-induced mortality in Split-Dalmatia County, Croatia

    PubMed Central

    Marasović Šušnjara, Ivana; Definis Gojanović, Marija; Vodopija, Davor; Čapkun, Vesna; Smoljanović, Ankica

    2011-01-01

    Aim To study drug-induced mortality and characteristics of overdose deaths in the war (1991-1995), pre-war (1986-1990), and post-war period (1996-2000) in Split-Dalmatia County. Methods We retrospectively searched through Databases of the Department of Forensic Medicine, University Hospital Split, the national register of death records, the archives of the Split-Dalmatia County Police, and the Register of Treated Drug Addicts of the Croatian National Institute of Public Health, covering the period from 1986 to 2000, according to drug poisoning codes IX and X of the International Classification of Diseases. The indicators were statistically analyzed. Results There were 146 registered drug-induced deaths, with 136 (93%) deceased being men. The median age of all cases was 27 years (interquartile range 8). Most of them were single (70.6%), unemployed (44.6%), and secondary school graduates (69.2%). In the war period, there were 4.8 times more deaths than in the pre-war period (P = 0.014), and in the post-war period there were 5.2 times more deaths than in the pre-war period (P = 0.008). The most common site of death was the deceased person’s home. The toxicological analyses showed that 59 (61%) deaths were heroin related, alcohol use was found in 62 cases (42.5%), and multi-substance use was found in more than a half of the cases. In 133 (91.1%) cases, deaths were classified as unintentional, whereas 13 (8.9%) were classified as suicides. Conclusion The war, along with other risk factors, contributed to unfavorable developments related to drug abuse in Split-Dalmatia County, including the increase in the drug-induced mortality rate. PMID:21990081

  6. Influence of war on quantitative and qualitative changes in drug-induced mortality in Split-Dalmatia County, Croatia.

    PubMed

    Marasovic Susnjara, Ivana; Definis Gojanovic, Marija; Vodopija, Davor; Capkun, Vesna; Smoljanovic, Ankica

    2011-10-15

    To study drug-induced mortality and characteristics of overdose deaths in the war (1991-1995), pre-war (1986-1990), and post-war period (1996-2000) in Split-Dalmatia County. We retrospectively searched through Databases of the Department of Forensic Medicine, University Hospital Split, the national register of death records, the archives of the Split-Dalmatia County Police, and the Register of Treated Drug Addicts of the Croatian National Institute of Public Health, covering the period from 1986 to 2000, according to drug poisoning codes IX and X of the International Classification of Diseases. The indicators were statistically analyzed. There were 146 registered drug-induced deaths, with 136 (93%) deceased being men. The median age of all cases was 27 years (interquartile range 8). Most of them were single (70.6%), unemployed (44.6%), and secondary school graduates (69.2%). In the war period, there were 4.8 times more deaths than in the pre-war period (P=0.014), and in the post-war period there were 5.2 times more deaths than in the pre-war period (P=0.008). The most common site of death was the deceased person's home. The toxicological analyses showed that 59 (61%) deaths were heroin related, alcohol use was found in 62 cases (42.5%), and multi-substance use was found in more than a half of the cases. In 133 (91.1%) cases, deaths were classified as unintentional, whereas 13 (8.9%) were classified as suicides. CONCLUSION; The war, along with other risk factors, contributed to unfavorable developments related to drug abuse in Split-Dalmatia County, including the increase in the drug-induced mortality rate.

  7. Experimental assessment of advanced Stirling component concepts

    NASA Technical Reports Server (NTRS)

    Ziph, B.

    1985-01-01

    The results of an experimental assessment of some advanced Stirling engine component concepts are presented. High performance piston rings, reciprocating oil scrapers and heat pipes with getters and with mechanical couplings were tested. The tests yielded the following results: (1) Bonded, split, pumping piston rings, in preliminary testing, proved a promising concept, exhibiting low leakage and friction losses. Solid piston rings proved impractical in view of their sensitivity to the operating temperature; (2) A babbit oil scraper in a compliant housing performed well in atmospheric endurance testing. In pressurized tests the scraper did not perform well as a containment seal. The latter tests suggest modifications which may adapt Ti successfully to that application; and (3) Heat pipe endurance tests indicated the adequacy of simple, inexpensive fabrication and filling procedures. Getters were provided to increase the tolerance of the heat pipes to the presence of air and commercially available couplings were demonstrated to be suitable for heat pipe application. In addition to the above tests, the program also included a design effort for a split shaft applicable to a swashplate driven engine with a pressurized crank-case. The design is aimed, and does accomplish, an increase in component life to more than 10,000 hours.

  8. 49 CFR 40.199 - What problems always cause a drug test to be cancelled?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... specimen has been “Rejected for Testing” (with the reason stated). You must always cancel such a test. (b... seal is broken or shows evidence of tampering (and a split specimen cannot be redesignated, see § 40.83...

  9. Broadband non-polarizing terahertz beam splitters with variable split ratio

    NASA Astrophysics Data System (ADS)

    Wei, Minggui; Xu, Quan; Wang, Qiu; Zhang, Xueqian; Li, Yanfeng; Gu, Jianqiang; Tian, Zhen; Zhang, Xixiang; Han, Jiaguang; Zhang, Weili

    2017-08-01

    Seeking effective terahertz functional devices has always aroused extensive attention. Of particular interest is the terahertz beam splitter. Here, we have proposed, designed, manufactured, and tested a broadband non-polarizing terahertz beam splitter with a variable split ratio based on an all-dielectric metasurface. The metasurface was created by patterning a dielectric surface of the N-step phase gradient and etching to a few hundred micrometers. The conversion efficiency as high as 81% under the normal incidence at 0.7 THz was achieved. Meanwhile, such a splitter works well over a broad frequency range. The split ratio of the proposed design can be continuously tuned by simply shifting the metasurface, and the angle of emergences can also be easily adjusted by choosing the step of phase gradients. The proposed design is non-polarizing, and its performance is kept under different polarizations.

  10. Data splitting for artificial neural networks using SOM-based stratified sampling.

    PubMed

    May, R J; Maier, H R; Dandy, G C

    2010-03-01

    Data splitting is an important consideration during artificial neural network (ANN) development where hold-out cross-validation is commonly employed to ensure generalization. Even for a moderate sample size, the sampling methodology used for data splitting can have a significant effect on the quality of the subsets used for training, testing and validating an ANN. Poor data splitting can result in inaccurate and highly variable model performance; however, the choice of sampling methodology is rarely given due consideration by ANN modellers. Increased confidence in the sampling is of paramount importance, since the hold-out sampling is generally performed only once during ANN development. This paper considers the variability in the quality of subsets that are obtained using different data splitting approaches. A novel approach to stratified sampling, based on Neyman sampling of the self-organizing map (SOM), is developed, with several guidelines identified for setting the SOM size and sample allocation in order to minimize the bias and variance in the datasets. Using an example ANN function approximation task, the SOM-based approach is evaluated in comparison to random sampling, DUPLEX, systematic stratified sampling, and trial-and-error sampling to minimize the statistical differences between data sets. Of these approaches, DUPLEX is found to provide benchmark performance with good model performance, with no variability. The results show that the SOM-based approach also reliably generates high-quality samples and can therefore be used with greater confidence than other approaches, especially in the case of non-uniform datasets, with the benefit of scalability to perform data splitting on large datasets. Copyright 2009 Elsevier Ltd. All rights reserved.

  11. Lower extremity sagittal joint moment production during split-belt treadmill walking

    PubMed Central

    Roemmich, Ryan T.; Stegemöller, Elizabeth L.; Hass, Chris J.

    2012-01-01

    The split-belt treadmill (SBT) has recently been used to rehabilitate locomotor asymmetries in clinical populations. However, the joint mechanics produced while walking on a SBT are not well-understood. The purpose of this study was to investigate the lower extremity sagittal joint moments produced by each limb during SBT walking and provide insight as to how these joint moment patterns may be useful in rehabilitating unilateral gait deficits. Thirteen healthy young volunteers walked on the SBT with the belts tied and in a “SPLIT” session in which one belt moved twice as fast as the other. Sagittal lower extremity joint moment and ground reaction force impulses were then calculated over the braking and propulsive phases of the gait cycle. Paired t-tests were performed to analyze magnitude differences between conditions (i.e. the fast and slow limbs during SPLIT vs. the same limb during tied-belt walking) and between the fast and slow limbs during SPLIT. During the SPLIT session, the fast limb produced higher ground reaction force and ankle moment impulses during the propulsive and braking phases, and lower knee moment impulses during the propulsive phase when compared to the slow limb. The knee moment impulse was also significantly higher during braking in the slow limb than in the fast limb. The mechanics of each limb during the SPLIT session also differed from the mechanics observed when the belt speeds were tied. Based on these findings, we suggest that each belt may have intrinsic value in rehabilitating specific unilateral locomotor deficits. PMID:22985473

  12. Composition of legume soaking water and emulsifying properties in gluten-free bread.

    PubMed

    Huang, San; Liu, Yuling; Zhang, Weihan; Dale, Kylie J; Liu, Silu; Zhu, Jingnan; Serventi, Luca

    2018-04-01

    Soaking of legumes results in the loss of macronutrients, micronutrients and phytochemicals. Fibre, protein and phytochemicals found in legumes exert emulsifying activity that may improve the structure and texture of gluten-free bread. The legume soaking water of haricot beans, garbanzo chickpeas, whole green lentils, split yellow peas and yellow soybeans were tested in this study for functional properties and use as food ingredients. Composition, physicochemical properties and effect on the quality of gluten-free bread were determined for each legume soaking water. Haricot beans and split yellow peas released the highest amount of solids in the legume soaking water: 1.89 and 2.38 g/100 g, respectively. Insoluble fibre was the main constituent of haricot beans legume soaking water, while water-soluble carbohydrates and protein were the major fraction of split yellow peas. High quantities of phenolics (∼400 µg/g) and saponins (∼3 mg/g) were found in the legume soaking water of haricot beans, whole green lentils and split yellow peas. High emulsifying activity (46 and 50%) was found for the legume soaking water of garbanzo chickpeas and split yellow peas, probably due to their protein content and high ratio of water-soluble carbohydrates to dry matter. Such activity resulted in softer texture of the gluten-free bread. A homogeneous structure of crumb pores was found for split yellow peas, opposing that of whole green lentils. A balance between the contents of yeast nutrients and antinutrients was the likely basis of the different appearances.

  13. Fracture characterization from near-offset VSP inversion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horne, S.; MacBeth, C.; Queen, J.

    1997-01-01

    A global optimization method incorporating a ray-tracing scheme is used to invert observations of shear-wave splitting from two near-offset VSPs recorded at the Conoco Borehole Test Facility, Kay County, Oklahoma. Inversion results suggest that the seismic anisotropy is due to a non-vertical fracture system. This interpretation is constrained by the VSP acquisition geometry for which two sources are employed along near diametrically opposite azimuths about the well heads. A correlation is noted between the time-delay variations between the fast and slow split shear waves and the sandstone formations.

  14. Upwind differencing and LU factorization for chemical non-equilibrium Navier-Stokes equations

    NASA Technical Reports Server (NTRS)

    Shuen, Jian-Shun

    1992-01-01

    By means of either the Roe or the Van Leer flux-splittings for inviscid terms, in conjunction with central differencing for viscous terms in the explicit operator and the Steger-Warming splitting and lower-upper approximate factorization for the implicit operator, the present, robust upwind method for solving the chemical nonequilibrium Navier-Stokes equations yields formulas for finite-volume discretization in general coordinates. Numerical tests in the illustrative cases of a hypersonic blunt body, a ramped duct, divergent nozzle flows, and shock wave/boundary layer interactions, establish the method's efficiency.

  15. A three-dimensional parabolic equation model of sound propagation using higher-order operator splitting and Padé approximants.

    PubMed

    Lin, Ying-Tsong; Collis, Jon M; Duda, Timothy F

    2012-11-01

    An alternating direction implicit (ADI) three-dimensional fluid parabolic equation solution method with enhanced accuracy is presented. The method uses a square-root Helmholtz operator splitting algorithm that retains cross-multiplied operator terms that have been previously neglected. With these higher-order cross terms, the valid angular range of the parabolic equation solution is improved. The method is tested for accuracy against an image solution in an idealized wedge problem. Computational efficiency improvements resulting from the ADI discretization are also discussed.

  16. Prognostic significance of blood coagulation tests in carcinoma of the lung and colon.

    PubMed

    Wojtukiewicz, M Z; Zacharski, L R; Moritz, T E; Hur, K; Edwards, R L; Rickles, F R

    1992-08-01

    Blood coagulation test results were collected prospectively in patients with previously untreated, advanced lung or colon cancer who entered into a clinical trial. In patients with colon cancer, reduced survival was associated (in univariate analysis) with higher values obtained at entry to the study for fibrinogen, fibrin(ogen) split products, antiplasmin, and fibrinopeptide A and accelerated euglobulin lysis times. In patients with non-small cell lung cancer, reduced survival was associated (in univariate analysis) with higher fibrinogen and fibrin(ogen) split products, platelet counts and activated partial thromboplastin times. In patients with small cell carcinoma of the lung, only higher activated partial thromboplastin times were associated (in univariate analysis) with reduced survival in patients with disseminated disease. In multivariate analysis, higher activated partial thromboplastin times were a significant independent predictor of survival for patients with non-small cell lung cancer limited to one hemithorax and with disseminated small cell carcinoma of the lung. Fibrin(ogen) split product levels were an independent predictor of survival for patients with disseminated non-small cell lung cancer as were both the fibrinogen and fibrinopeptide A levels for patients with disseminated colon cancer. These results suggest that certain tests of blood coagulation may be indicative of prognosis in lung and colon cancer. The heterogeneity of these results suggests that the mechanism(s), intensity, and pathophysiological significance of coagulation activation in cancer may differ between tumour types.

  17. Dynamic testing and test anxiety amongst gifted and average-ability children.

    PubMed

    Vogelaar, Bart; Bakker, Merel; Elliott, Julian G; Resing, Wilma C M

    2017-03-01

    Dynamic testing has been proposed as a testing approach that is less disadvantageous for children who may be potentially subject to bias when undertaking conventional assessments. For example, those who encounter high levels of test anxiety, or who are unfamiliar with standardized test procedures, may fail to demonstrate their true potential or capabilities. While dynamic testing has proven particularly useful for special groups of children, it has rarely been used with gifted children. We investigated whether it would be useful to conduct a dynamic test to measure the cognitive abilities of intellectually gifted children. We also investigated whether test anxiety scores would be related to a progression in the children's test scores after dynamic training. Participants were 113 children aged between 7 and 8 years from several schools in the western part of the Netherlands. The children were categorized as either gifted or average-ability and split into an unguided practice or a dynamic testing condition. The study employed a pre-test-training-post-test design. Using linear mixed modelling analysis with a multilevel approach, we inspected the growth trajectories of children in the various conditions and examined the impact of ability and test anxiety on progression and training benefits. Dynamic testing proved to be successful in improving the scores of the children, although no differences in training benefits were found between gifted and average-ability children. Test anxiety was shown to influence the children's rate of change across all test sessions and their improvement in performance accuracy after dynamic training. © 2016 The British Psychological Society.

  18. Mechanical properties and durability of crumb rubber concrete

    NASA Astrophysics Data System (ADS)

    Chylík, Roman; Trtík, Tomáš; Fládr, Josef; Bílý, Petr

    2017-09-01

    This paper is focused on concrete with admixture of rubber powder, generally called crumb rubber concrete (CRC). The inspiration was found in Arizona, where one of the first CRCs has been created. However, Arizona has completely different climates than Central Europe. Could we use the crumb rubber concrete on construction applications in the Central European climate too? The paper evaluates the influence of the rubber powder on material characteristics and durability of CRC. CRCs with various contents of fine and coarse crumb powder were compared. The tested parameters were slump, air content, permeability, resistance of concrete to water with deicing chemicals, compressive and splitting tensile strength. The tests showed that workability, compressive strength and permeability decreased as the amount of rubber increased, but the air content increased as the rubber content increased. Photos of air voids in cement matrix from electron microscope were captured. The results of laboratory tests showed that admixture of rubber powder in concrete could have a positive impact on durability of concrete and concurrently contribute to sustainable development. Considering the lower compressive strength, CRC is recommended for use in applications where the high strength of concrete is not required.

  19. 75 FR 8646 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... methodological research on questionnaire design and evaluation (split-ballot field tests, respondent debriefings... ASEC design. A secondary purpose is to compare estimates from the CPS and ACS test panels. Evaluations... and ACS production data, and to determine whether particular survey design features of the CPS ASEC...

  20. Using a Split-belt Treadmill to Evaluate Generalization of Human Locomotor Adaptation.

    PubMed

    Vasudevan, Erin V L; Hamzey, Rami J; Kirk, Eileen M

    2017-08-23

    Understanding the mechanisms underlying locomotor learning helps researchers and clinicians optimize gait retraining as part of motor rehabilitation. However, studying human locomotor learning can be challenging. During infancy and childhood, the neuromuscular system is quite immature, and it is unlikely that locomotor learning during early stages of development is governed by the same mechanisms as in adulthood. By the time humans reach maturity, they are so proficient at walking that it is difficult to come up with a sufficiently novel task to study de novo locomotor learning. The split-belt treadmill, which has two belts that can drive each leg at a different speed, enables the study of both short- (i.e., immediate) and long-term (i.e., over minutes-days; a form of motor learning) gait modifications in response to a novel change in the walking environment. Individuals can easily be screened for previous exposure to the split-belt treadmill, thus ensuring that all experimental participants have no (or equivalent) prior experience. This paper describes a typical split-belt treadmill adaptation protocol that incorporates testing methods to quantify locomotor learning and generalization of this learning to other walking contexts. A discussion of important considerations for designing split-belt treadmill experiments follows, including factors like treadmill belt speeds, rest breaks, and distractors. Additionally, potential but understudied confounding variables (e.g., arm movements, prior experience) are considered in the discussion.

  1. Split-Step Timing of Professional and Junior Tennis Players

    PubMed Central

    Leskosek, Bojan; Filipcic, Tjasa

    2017-01-01

    Abstract The purpose of the study was to determine the timing of a split-step in three categories of tennis players in four groups of strokes. Subjects were divided into three groups: male and female junior, and male professional tennis players. During two tournaments, all matches were recorded with two fixed video cameras. For every stroke, the timing of the split-step between the opponent’s impact point when hitting the ball and the player’s split-step was measured. A two-way analysis of variance (ANOVA) was used to determine the differences between groups of strokes, players and the interaction Player x Stroke Group. A Tukey post-hoc test was employed to determine specific differences. The results revealed differences between players in detecting the opponent’s movement, stroke and ball flight, which were reflected in different split-step timings. Each tennis player has his/her own timing mechanism which they adapt to various game situations. Response times differ significantly depending on the game situation. On average, they are the lowest in the serve, and then gradually rise from the return of the serve to baseline game, reaching the highest values in specific game situations. Players react faster in the first serve than in the second one and in the return of the serve, the response times are lower after the return of the second serve PMID:28210342

  2. Volume holographic lens spectrum-splitting photovoltaic system for high energy yield with direct and diffuse solar illumination

    NASA Astrophysics Data System (ADS)

    Chrysler, Benjamin D.; Wu, Yuechen; Yu, Zhengshan; Kostuk, Raymond K.

    2017-08-01

    In this paper a prototype spectrum-splitting photovoltaic system based on volume holographic lenses (VHL) is designed, fabricated and tested. In spectrum-splitting systems, incident sunlight is divided in spectral bands for optimal conversion by a set of single-junction PV cells that are laterally separated. The VHL spectrumsplitting system in this paper has a form factor similar to conventional silicon PV modules but with higher efficiencies (>30%). Unlike many other spectrum-splitting systems that have been proposed in the past, the system in this work converts both direct and diffuse sunlight while using inexpensive 1-axis tracking systems. The VHL system uses holographic lenses that focus light at a transition wavelength to the boundary between two PV cells. Longer wavelength light is dispersed to the narrow bandgap cell and shorter wavelength light to the wide bandgap cell. A prototype system is designed with silicon and GaAs PV cells. The holographic lenses are fabricated in Covestro Bayfol HX photopolymer by `stitching' together lens segments through sequential masked exposures. The PV cells and holographic lenses were characterized and the data was used in a raytrace simulation and predicts an improvement in total power output of 15.2% compared to a non-spectrum-splitting reference. A laboratory measurement yielded an improvement in power output of 8.5%.

  3. Constitutive modeling of polycarbonate over a wide range of strain rates and temperatures

    NASA Astrophysics Data System (ADS)

    Wang, Haitao; Zhou, Huamin; Huang, Zhigao; Zhang, Yun; Zhao, Xiaoxuan

    2017-02-01

    The mechanical behavior of polycarbonate was experimentally investigated over a wide range of strain rates (10^{-4} to 5× 103 s^{-1}) and temperatures (293 to 353 K). Compression tests under these conditions were performed using a SHIMADZU universal testing machine and a split Hopkinson pressure bar. Falling weight impact testing was carried out on an Instron Dynatup 9200 drop tower system. The rate- and temperature-dependent deformation behavior of polycarbonate was discussed in detail. Dynamic mechanical analysis (DMA) tests were utilized to observe the glass (α ) transition and the secondary (β ) transition of polycarbonate. The DMA results indicate that the α and β transitions have a dramatic influence on the mechanical behavior of polycarbonate. The decompose/shift/reconstruct (DSR) method was utilized to decompose the storage modulus into the α and β components and extrapolate the entire modulus, the α-component modulus and the β-component modulus. Based on three previous models, namely, Mulliken-Boyce, G'Sell-Jonas and DSGZ, an adiabatic model is proposed to predict the mechanical behavior of polycarbonate. The model considers the contributions of both the α and β transitions to the mechanical behavior, and it has been implemented in ABAQUS/Explicit through a user material subroutine VUMAT. The model predictions are proven to essentially coincide with the experimental results during compression testing and falling weight impact testing.

  4. Broad-spectrum enhanced absorption of graphene-molybdenum disulfide photovoltaic cells in metal-mirror microcavity.

    PubMed

    Jiang-Tao, Liu; Yun-Kai, Cao; Hong, Tong; Dai-Qiang, Wang; Zhen-Hua, Wu

    2018-04-06

    The optical absorption of graphene-molybdenum disulfide photovoltaic cells (GM-PVc) in wedge-shaped metal-mirror microcavities (w-MMCs) combined with a spectrum-splitting structure was studied. Results showed that the combination of spectrum-splitting structure and w-MMC can enable the light absorption of GM-PVcs to reach about 65% in the broad spectrum. The influence of processing errors on the absorption of GM-PVcs in w-MMCs was 3-14 times lower than that of GM-PVcs in wedge photonic crystal microcavities. The light absorption of GM-PVcs reached 60% in the broad spectrum, even with the processing errors. The proposed structure is easy to implement and may have potentially important applications in the development of ultra-thin and high-efficiency solar cells and optoelectronic devices.

  5. Broad-spectrum enhanced absorption of graphene-molybdenum disulfide photovoltaic cells in metal-mirror microcavity

    NASA Astrophysics Data System (ADS)

    Jiang-Tao, Liu; Yun-Kai, Cao; Hong, Tong; Dai-Qiang, Wang; Zhen-Hua, Wu

    2018-04-01

    The optical absorption of graphene-molybdenum disulfide photovoltaic cells (GM-PVc) in wedge-shaped metal-mirror microcavities (w-MMCs) combined with a spectrum-splitting structure was studied. Results showed that the combination of spectrum-splitting structure and w-MMC can enable the light absorption of GM-PVcs to reach about 65% in the broad spectrum. The influence of processing errors on the absorption of GM-PVcs in w-MMCs was 3-14 times lower than that of GM-PVcs in wedge photonic crystal microcavities. The light absorption of GM-PVcs reached 60% in the broad spectrum, even with the processing errors. The proposed structure is easy to implement and may have potentially important applications in the development of ultra-thin and high-efficiency solar cells and optoelectronic devices.

  6. Crack propagation of brittle rock under high geostress

    NASA Astrophysics Data System (ADS)

    Liu, Ning; Chu, Weijiang; Chen, Pingzhi

    2018-03-01

    Based on fracture mechanics and numerical methods, the characteristics and failure criterions of wall rock cracks including initiation, propagation, and coalescence are analyzed systematically under different conditions. In order to consider the interaction among cracks, adopt the sliding model of multi-cracks to simulate the splitting failure of rock in axial compress. The reinforcement of bolts and shotcrete supporting to rock mass can control the cracks propagation well. Adopt both theory analysis and simulation method to study the mechanism of controlling the propagation. The best fixed angle of bolts is calculated. Then use ansys to simulate the crack arrest function of bolt to crack. Analyze the influence of different factors on stress intensity factor. The method offer more scientific and rational criterion to evaluate the splitting failure of underground engineering under high geostress.

  7. Music Preferences with Regard to Music Education, Informal Infuences and Familiarity of Music Amongst Young People in Croatia

    ERIC Educational Resources Information Center

    Dobrota, Snježana; Ercegovac, Ina Reic

    2017-01-01

    The aim of this research was to investigate the relationship between music preference and music education, informal influences (attending classical music concerts and musical theatre productions) and familiarity of music. The research included students of the Faculty of Humanities and Social Sciences, University of Split (N = 341). The results…

  8. The Influence of Moral Disengagement, Morally Based Self-Esteem, Age, and Gender on Traditional Bullying and Cyberbullying

    ERIC Educational Resources Information Center

    Robson, Claire; Witenberg, Rivka T.

    2013-01-01

    The current study investigated moral disengagement, morally based self-esteem, age, and gender as predictors of traditional bullying and cyberbullying. The participants were 210 Australian school students aged 12 to 15, evenly split between males and females. Salient predictors of traditional bullying were overall moral disengagement, and the…

  9. Influence of pine straw harvesting, prescribed fire, and fertilization on a Louisiana longleaf pine site

    Treesearch

    James D. Haywood

    2009-01-01

    This research was initiated in a 34-year-old, direct-seeded stand of longleaf pine (Pinus palustris Mill.) to study how pine straw management practices (harvesting, fire, and fertilization) affected the longleaf pine overstory and pine straw yields. A randomized complete block split-plot design was installed with two main plot treatments...

  10. Evaluation of microtensile and tensile bond strength tests determining effects of erbium, chromium: yttrium-scandium-gallium-garnet laser pulse frequency on resin-enamel bonding.

    PubMed

    Yildirim, T; Ayar, M K; Yesilyurt, C; Kilic, S

    2016-01-01

    The aim of the present study was to compare two different bond strength test methods (tensile and microtensile) in investing the influence of erbium, chromium: yttrium-scandium-gallium-garnet (Er, Cr: YSGG) laser pulse frequency on resin-enamel bonding. One-hundred and twenty-five bovine incisors were used in the present study. Two test methods were used: Tensile bond strength (TBS; n = 20) and micro-TBS (μTBS; n = 5). Those two groups were further split into three subgroups according to Er, Cr: YSGG laser frequency (20, 35, and 50 Hz). Following adhesive procedures, microhybrid composite was placed in a custom-made bonding jig for TBS testing and incrementally for μTBS testing. TBS and μTBS tests were carried out using a universal testing machine and a microtensile tester, respectively. Analysis of TBS results showed that means were not significantly different. For μTBS, the Laser-50 Hz group showed the highest bond strength (P < 0.05), and increasing frequency significantly increased bond strength (P < 0.05). Comparing the two tests, the μTBS results showed higher means and lower standard deviations. It was demonstrated that increasing μTBS pulse frequency significantly improved immediate bond strength while TBS showed no significant effect. It can, therefore, be concluded that test method may play a significant role in determining optimum laser parameters for resin bonding.

  11. The influence of underlying topography on lava channel networks and flow behavior (Invited)

    NASA Astrophysics Data System (ADS)

    Dietterich, H. R.; Cashman, K. V.; Rust, A.

    2013-12-01

    New high resolution mapping of historical lava flows in Hawai';i reveals complex topographically controlled channel networks. Network morphologies range from distributary systems dominated by branching around local obstacles, to tributary systems constricted by topographic confinement. Because channel networks govern the distribution of lava within the flow, they can dramatically alter the effective volumetric flux, which affects both flow length and advance rate. The influence of flow bifurcations is evidenced by (1) channelized flows from Pu';u ';O';o episodes 1-20 at Kilauea Volcano, where flow front velocities decreased by approximately half each time a flow split, and (2) the length of confined flows, such as the Mauna Loa 1859 flow, which traveled twice as far as the distributary Mauna Loa 1984 flow, despite similar effusion rates and durations. To study the underlying controls on flow bifurcations, we have undertaken a series of analogue experiments with golden syrup (a Newtonian fluid) to better understand the physics of obstacle interaction and its influence on flow behavior and morphology. Controlling the effusion rate and surface slope, we extrude flows onto a surface with a cylindrical or V-shaped obstacle of variable angle. When the flow is sufficiently fast, a stationary wave forms upslope of the obstacle; if the stationary wave is sufficiently high, the flow can overtop, rather than split around, the obstacle. The stationary wave height increases with flow velocity and with the effective obstacle width. Evidence for stationary waves in Hawaiian lava flows comes from both photographs of active flows and waveforms frozen into solidified flows. We have also performed a preliminary set of similar experiments with molten basalt to identify the effect of cooling and investigate flow merging. In these experiments, a stationary wave develops upslope of the obstacle, which allows the surface to cool and thicken. After splitting, the syrup experiments show minimal impact of the split on flow advance, except in cases where the flow is very thin, and surface tension controls the flow behavior. In contrast, the experiments with molten basalt slow markedly, as measured by both flow front and surface velocities. This difference demonstrates the effect of cooling and crust formation on flowing lava. Crust formation also controls the ability of split flows to merge below an obstacle, such that flows can converge only at high flow rates, which limits time for crust formation, and at narrow obstacle angles, which limits the lateral spreading required for convergence. Our experiments qualitatively support theoretical descriptions of crustal controls on flow spreading and levee development, but our poor knowledge of the appropriate parameter values, particularly that of the strength of the viscoelastic crust, prevents a quantitative comparison. These experiments, and our observations from natural systems, have significant implications for predicting lava flow behavior and inform efforts to mitigate flow hazards with diversion barriers.

  12. Design of a factorial experiment with randomization restrictions to assess medical device performance on vascular tissue.

    PubMed

    Diestelkamp, Wiebke S; Krane, Carissa M; Pinnell, Margaret F

    2011-05-20

    Energy-based surgical scalpels are designed to efficiently transect and seal blood vessels using thermal energy to promote protein denaturation and coagulation. Assessment and design improvement of ultrasonic scalpel performance relies on both in vivo and ex vivo testing. The objective of this work was to design and implement a robust, experimental test matrix with randomization restrictions and predictive statistical power, which allowed for identification of those experimental variables that may affect the quality of the seal obtained ex vivo. The design of the experiment included three factors: temperature (two levels); the type of solution used to perfuse the artery during transection (three types); and artery type (two types) resulting in a total of twelve possible treatment combinations. Burst pressures of porcine carotid and renal arteries sealed ex vivo were assigned as the response variable. The experimental test matrix was designed and carried out as a split-plot experiment in order to assess the contributions of several variables and their interactions while accounting for randomization restrictions present in the experimental setup. The statistical software package SAS was utilized and PROC MIXED was used to account for the randomization restrictions in the split-plot design. The combination of temperature, solution, and vessel type had a statistically significant impact on seal quality. The design and implementation of a split-plot experimental test-matrix provided a mechanism for addressing the existing technical randomization restrictions of ex vivo ultrasonic scalpel performance testing, while preserving the ability to examine the potential effects of independent factors or variables. This method for generating the experimental design and the statistical analyses of the resulting data are adaptable to a wide variety of experimental problems involving large-scale tissue-based studies of medical or experimental device efficacy and performance.

  13. Men appear more lateralized when noticing emotion in male faces.

    PubMed

    Rahman, Qazi; Anchassi, Tarek

    2012-02-01

    Empirical tests of the "right hemisphere dominance" versus "valence" theories of emotion processing are confounded by known sex differences in lateralization. Moreover, information about the sex of the person posing an emotion might be processed differently by men and women because of an adaptive male bias to notice expressions of threat and vigilance in other male faces. The purpose of this study was to investigate whether sex of poser and emotion displayed influenced lateralization in men and women by analyzing "laterality quotient" scores on a test which depicts vertically split chimeric faces, formed with one half showing a neutral expression and the other half showing an emotional expression. We found that men (N = 50) were significantly more lateralized for emotions indicative of vigilance and threat (happy, sad, angry, and surprised) in male faces relative to female faces and compared to women (N = 44). These data indicate that sex differences in functional cerebral lateralization for facial emotion may be specific to the emotion presented and the sex of face presenting it. PsycINFO Database Record (c) 2012 APA, all rights reserved

  14. Relationship between organizational justice and organizational safety climate: do fairness perceptions influence employee safety behaviour?

    PubMed

    Gyekye, Seth Ayim; Haybatollahi, Mohammad

    2014-01-01

    This study investigated the relationships between organizational justice, organizational safety climate, job satisfaction, safety compliance and accident frequency. Ghanaian industrial workers participated in the study (N = 320). Safety climate and justice perceptions were assessed with Hayes, Parender, Smecko, et al.'s (1998) and Blader and Tyler's (2003) scales respectively. A median split was performed to dichotomize participants into 2 categories: workers with positive and workers with negative justice perceptions. Confirmatory factors analysis confirmed the 5-factor structure of the safety scale. Regression analyses and t tests indicated that workers with positive fairness perceptions had constructive perspectives regarding workplace safety, expressed greater job satisfaction, were more compliant with safety policies and registered lower accident rates. These findings provide evidence that the perceived level of fairness in an organization is closely associated with workplace safety perception and other organizational factors which are important for safety. The implications for safety research are discussed.

  15. Laser interferometer for space-based mapping of Earth's gravity field

    NASA Astrophysics Data System (ADS)

    Dehne, Marina; Sheard, Benjamin; Gerberding, Oliver; Mahrdt, Christoph; Heinzel, Gerhard; Danzmann, Karsten

    2010-05-01

    Laser interferometry will play a key role in the next generation of GRACE-type satellite gravity missions. The measurement concepts for future missions include a heterodyne laser interferometer. Furthermore, it is favourable to use polarising components in the laser interferometer for beam splitting. In the first step the influence of these components on the interferometer sensitivity has been investigated. Additionally, a length stability on a nm-scale has been validated. The next step will include a performance test of an interferometric SST system in an active symmetric transponder setup including two lasers and two optical benches. The design and construction of a quasi-monolithic interferometer for comparing the interferometric performance of non-polarising and polarising optics will be discussed. The results of the interferometric readout of a heterodyne configuration together with polarising optics will be presented to fulfil the phase sensitivity requirement of 1nm/√Hz-- for a typical SSI scenario.

  16. Toward a General Approach for RNA-Templated Hierarchical Assembly of Split-Proteins

    PubMed Central

    Furman, Jennifer L.; Badran, Ahmed H.; Ajulo, Oluyomi; Porter, Jason R.; Stains, Cliff I.; Segal, David J.; Ghosh, Indraneel

    2010-01-01

    The ability to conditionally turn on a signal or induce a function in the presence of a user-defined RNA target has potential applications in medicine and synthetic biology. Although sequence-specific pumilio repeat proteins can target a limited set of ssRNA sequences, there are no general methods for targeting ssRNA with designed proteins. As a first step toward RNA recognition, we utilized the RNA binding domain of argonaute, implicated in RNA interference, for specifically targeting generic 2-nucleotide, 3' overhangs of any dsRNA. We tested the reassembly of a split-luciferase enzyme guided by argonaute-mediated recognition of newly generated nucleotide overhangs when ssRNA is targeted by a designed complementary guide sequence. This approach was successful when argonaute was utilized in conjunction with a pumilio repeat and expanded the scope of potential ssRNA targets. However, targeting any desired ssRNA remained elusive as two argonaute domains provided minimal reassembled split-luciferase. We next designed and tested a second hierarchical assembly, wherein ssDNA guides are appended to DNA hairpins that serve as a scaffold for high affinity zinc fingers attached to split-luciferase. In the presence of a ssRNA target containing adjacent sequences complementary to the guides, the hairpins are brought into proximity, allowing for zinc finger binding and concomitant reassembly of the fragmented luciferase. The scope of this new approach was validated by specifically targeting RNA encoding VEGF, hDM2, and HER2. These approaches provide potentially general design paradigms for the conditional reassembly of fragmented proteins in the presence of any desired ssRNA target. PMID:20681585

  17. Study on Mechanical Properties of Hybrid Fiber Reinforced Concrete

    NASA Astrophysics Data System (ADS)

    He, Dongqing; Wu, Min; Jie, Pengyu

    2017-12-01

    Several common high elastic modulus fibers (steel fibers, basalt fibers, polyvinyl alcohol fibers) and low elastic modulus fibers (polypropylene fiber) are incorporated into the concrete, and its cube compressive strength, splitting tensile strength and flexural strength are studied. The test result and analysis demonstrate that single fiber and hybrid fiber will improve the integrity of the concrete at failure. The mechanical properties of hybrid steel fiber-polypropylene fiber reinforced concrete are excellent, and the cube compressive strength, splitting tensile strength and flexural strength respectively increase than plain concrete by 6.4%, 3.7%, 11.4%. Doped single basalt fiber or polypropylene fiber and basalt fibers hybrid has little effect on the mechanical properties of concrete. Polyvinyl alcohol fiber and polypropylene fiber hybrid exhibit ‘negative confounding effect’ on concrete, its splitting tensile and flexural strength respectively are reduced by 17.8% and 12.9% than the single-doped polyvinyl alcohol fiber concrete.

  18. Split gradient coils for simultaneous PET-MRI

    PubMed Central

    Poole, Michael; Bowtell, Richard; Green, Dan; Pittard, Simon; Lucas, Alun; Hawkes, Rob; Carpenter, Adrian

    2015-01-01

    Combining positron emission tomography (PET) and MRI necessarily involves an engineering tradeoff as the equipment needed for the two modalities vies for the space closest to the region where the signals originate. In one recently described scanner configuration for simultaneous positron emission tomography–MRI, the positron emission tomography detection scintillating crystals reside in an 80-mm gap between the 2 halves of a 1-T split-magnet cryostat. A novel set of gradient and shim coils has been specially designed for this split MRI scanner to include an 110-mm gap from which wires are excluded so as not to interfere with positron detection. An inverse boundary element method was necessarily employed to design the three orthogonal, shielded gradient coils and shielded Z0 shim coil. The coils have been constructed and tested in the hybrid positron emission tomography-MRI system and successfully used in simultaneous positron emission tomography-MRI experiments. PMID:19780167

  19. Giant switchable Rashba effect in oxide heterostructures

    DOE PAGES

    Zhong, Zhicheng; Si, Liang; Zhang, Qinfang; ...

    2015-03-01

    One of the most fundamental phenomena and a reminder of the electron’s relativistic nature is the Rashba spin splitting for broken inversion symmetry. Usually this splitting is a tiny relativistic correction. Interfacing ferroelectric BaTiO₃ and a 5d (or 4d) transition metal oxide with a large spin-orbit coupling, Ba(Os,Ir,Ru)O₃, we show that giant Rashba spin splittings are indeed possible and even controllable by an external electric field. Based on density functional theory and a microscopic tight binding understanding, we conclude that the electric field is amplified and stored as a ferroelectric Ti-O distortion which, through the network of oxygen octahedra, inducesmore » a large (Os,Ir,Ru)-O distortion. The BaTiO₃/Ba(Os,Ru,Ir)O₃ heterostructure is hence the ideal test station for switching and studying the Rashba effect and allows applications at room temperature.« less

  20. Gas-liquid flow splitting in T-junction with inclined lateral arm

    NASA Astrophysics Data System (ADS)

    Yang, Le-le; Liu, Shuo; Li, Hua; Zhang, Jian; Wu, Ying-xiang; Xu, Jing-yu

    2018-02-01

    This paper studies the gas-liquid flow splitting in T-junction with inclined lateral arm. The separation mechanism of the T-junction is related to the pressure distribution in the T-junction. It is shown that the separation efficiency strongly depends on the inclination angle, when the angle ranges from 0° to 30°, while not so strongly for angles in the range from 30° to 90° Increasing the number of connecting tubes is helpful for the gas-liquid separation, and under the present test conditions, with four connecting tubes, a good separation performance can be achieved. Accordingly, a multi-tube Y-junction separator with four connecting tubes is designed for the experimental investigation. A good agreement between the simulated and measured data shows that there is an optimal split ratio to achieve the best performance for the multi-tube Y-junction separator.

  1. Strain Measurements within Fibre Boards. Part II: Strain Concentrations at the Crack Tip of MDF Specimens Tested by the Wedge Splitting Method

    PubMed Central

    Sinn, Gerhard; Müller, Ulrich; Konnerth, Johannes; Rathke, Jörn

    2012-01-01

    This is the second part of an article series where the mechanical and fracture mechanical properties of medium density fiberboard (MDF) were studied. While the first part of the series focused on internal bond strength and density profiles, this article discusses the fracture mechanical properties of the core layer. Fracture properties were studied with a wedge splitting setup. The critical stress intensity factors as well as the specific fracture energies were determined. Critical stress intensity factors were calculated from maximum splitting force and two-dimensional isotropic finite elements simulations of the specimen geometry. Size and shape of micro crack zone were measured with electronic laser speckle interferometry. The process zone length was approx. 5 mm. The specific fracture energy was determined to be 45.2 ± 14.4 J/m2 and the critical stress intensity factor was 0.11 ± 0.02 MPa.

  2. Quasi-QSAR for mutagenic potential of multi-walled carbon-nanotubes.

    PubMed

    Toropov, Andrey A; Toropova, Alla P

    2015-04-01

    Available on the Internet, the CORAL software (http://www.insilico.eu/coral) has been used to build up quasi-quantitative structure-activity relationships (quasi-QSAR) for prediction of mutagenic potential of multi-walled carbon-nanotubes (MWCNTs). In contrast with the previous models built up by CORAL which were based on representation of the molecular structure by simplified molecular input-line entry system (SMILES) the quasi-QSARs based on the representation of conditions (not on the molecular structure) such as concentration, presence (absence) S9 mix, the using (or without the using) of preincubation were encoded by so-called quasi-SMILES. The statistical characteristics of these models (quasi-QSARs) for three random splits into the visible training set and test set and invisible validation set are the following: (i) split 1: n=13, r(2)=0.8037, q(2)=0.7260, s=0.033, F=45 (training set); n=5, r(2)=0.9102, s=0.071 (test set); n=6, r(2)=0.7627, s=0.044 (validation set); (ii) split 2: n=13, r(2)=0.6446, q(2)=0.4733, s=0.045, F=20 (training set); n=5, r(2)=0.6785, s=0.054 (test set); n=6, r(2)=0.9593, s=0.032 (validation set); and (iii) n=14, r(2)=0.8087, q(2)=0.6975, s=0.026, F=51 (training set); n=5, r(2)=0.9453, s=0.074 (test set); n=5, r(2)=0.8951, s=0.052 (validation set). Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Nanoscale Morphology to Macroscopic Performance in Ultra High Molecular Weight Polyethylene Fibers

    NASA Astrophysics Data System (ADS)

    McDaniel, Preston B.

    Ultra high molecular weight polyethylene (UHMWPE) fibers are increasingly used in high -performance applications where strength, stiffness, and the ability to dissipate energy are of critical importance. Despite their use in a variety of applications, the influence of morphological features at the meso/nanoscale on the macroscopic performance of the fibers has not been well understood. There is particular interest in gaining a better understanding of the nanoscale structure-property relationships in UHMWPE fibers used in ballistics applications. In order to accurately model and predict failure in the fiber, a more complete understanding of the complex load pathways that dictate the ways in which load is transferred through the fiber, across interfaces and length scales is required. The goal of the work discussed herein is to identify key meso/nanostructural features evolved in high performance fibers and determine how these features influence the performance of the fiber through a variety of different loading mechanisms. The important structural features in high-performance UHMWPE fibers are first identified through examination of the meso/nanostructure of a series of fibers with different processing conditions. This is achieved primarily through the use of wide-angle x-ray diffraction (WAXD) and atomic force microscopy (AFM). Analysis of AFM images and WAXD data allows identification and quantifications of important structural features at these length scales. Key meso/nanostructural features are then examined with respect to their influence on the transverse compression behavior of single fibers. Through post-mortem AFM analysis of samples at incremental compressive strains, the evolution of damage is examined and compared with macroscopic fiber mechanical response. It was found that collapse of mesoscale voids, followed by nanoscale fibrillation and reorganization of a fibrillar network has a significant influence on the mechanical response of the fiber. Through this work, the importance of nanoscale fibril adhesive interactions is highlighted. However, very little information exists in the literature as to the nature and magnitude of these interactions. Examination of nanoscale fibrillar adhesive interactions is experimentally difficult, and necessitated the development of an AFM based nanoscale splitting technique to quantify the interactions between fibrils. Through analysis of split geometry and careful partitioning of energies, the adhesive energy between fibrils in UHMWPE fibers are determined. The calculated average adhesive energies are significantly larger than the estimated energy due to van der Waals interactions, suggesting that there are physical connections (e.g., tie chains, tie fibrils, and lamellar crystalline bridges) that influence the interactions between fibrils. The interactions identified through this work are believed to be responsible for the creation of load pathways across fibril interfaces where load may be translated through the fiber in tension, compression, and shear. Finally, the nature of the mesoscale fibrillar network is explored through the development of a variable angle, single fiber peel test. This peel test enables the quantification of Mode I and Mode II peel energies. The modes of deformation observed in the peel test are representative of the mechanisms experienced during tensile and transverse compression loading. The quantification of peel energies in both Mode I and Mode II failure highlight the importance of the fibrillar network as a key mechanism for the translation of load through the fiber. In both modes of failure, the fibril network acts as a framework for the orientation and subsequent failure of nanoscale fibrils.

  4. Tabu search algorithm for the distance-constrained vehicle routing problem with split deliveries by order.

    PubMed

    Xia, Yangkun; Fu, Zhuo; Pan, Lijun; Duan, Fenghua

    2018-01-01

    The vehicle routing problem (VRP) has a wide range of applications in the field of logistics distribution. In order to reduce the cost of logistics distribution, the distance-constrained and capacitated VRP with split deliveries by order (DCVRPSDO) was studied. We show that the customer demand, which can't be split in the classical VRP model, can only be discrete split deliveries by order. A model of double objective programming is constructed by taking the minimum number of vehicles used and minimum vehicle traveling cost as the first and the second objective, respectively. This approach contains a series of constraints, such as single depot, single vehicle type, distance-constrained and load capacity limit, split delivery by order, etc. DCVRPSDO is a new type of VRP. A new tabu search algorithm is designed to solve the problem and the examples testing show the efficiency of the proposed algorithm. This paper focuses on constructing a double objective mathematical programming model for DCVRPSDO and designing an adaptive tabu search algorithm (ATSA) with good performance to solving the problem. The performance of the ATSA is improved by adding some strategies into the search process, including: (a) a strategy of discrete split deliveries by order is used to split the customer demand; (b) a multi-neighborhood structure is designed to enhance the ability of global optimization; (c) two levels of evaluation objectives are set to select the current solution and the best solution; (d) a discriminating strategy of that the best solution must be feasible and the current solution can accept some infeasible solution, helps to balance the performance of the solution and the diversity of the neighborhood solution; (e) an adaptive penalty mechanism will help the candidate solution be closer to the neighborhood of feasible solution; (f) a strategy of tabu releasing is used to transfer the current solution into a new neighborhood of the better solution.

  5. Tabu search algorithm for the distance-constrained vehicle routing problem with split deliveries by order

    PubMed Central

    Xia, Yangkun; Pan, Lijun; Duan, Fenghua

    2018-01-01

    The vehicle routing problem (VRP) has a wide range of applications in the field of logistics distribution. In order to reduce the cost of logistics distribution, the distance-constrained and capacitated VRP with split deliveries by order (DCVRPSDO) was studied. We show that the customer demand, which can’t be split in the classical VRP model, can only be discrete split deliveries by order. A model of double objective programming is constructed by taking the minimum number of vehicles used and minimum vehicle traveling cost as the first and the second objective, respectively. This approach contains a series of constraints, such as single depot, single vehicle type, distance-constrained and load capacity limit, split delivery by order, etc. DCVRPSDO is a new type of VRP. A new tabu search algorithm is designed to solve the problem and the examples testing show the efficiency of the proposed algorithm. This paper focuses on constructing a double objective mathematical programming model for DCVRPSDO and designing an adaptive tabu search algorithm (ATSA) with good performance to solving the problem. The performance of the ATSA is improved by adding some strategies into the search process, including: (a) a strategy of discrete split deliveries by order is used to split the customer demand; (b) a multi-neighborhood structure is designed to enhance the ability of global optimization; (c) two levels of evaluation objectives are set to select the current solution and the best solution; (d) a discriminating strategy of that the best solution must be feasible and the current solution can accept some infeasible solution, helps to balance the performance of the solution and the diversity of the neighborhood solution; (e) an adaptive penalty mechanism will help the candidate solution be closer to the neighborhood of feasible solution; (f) a strategy of tabu releasing is used to transfer the current solution into a new neighborhood of the better solution. PMID:29763419

  6. 21 CFR 866.5080 - Alpha-1-antichymotrypsin immunological test system.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... immunochemical techniques alpha-1-antichymotrypsin (a protein) in serum, other body fluids, and tissues. Alpha-1-antichymotrypsin helps protect tissues against proteolytic (protein-splitting) enzymes released during infection...

  7. Refrigeration for Cryogenic Sensors

    NASA Technical Reports Server (NTRS)

    Gasser, M. G. (Editor)

    1983-01-01

    Research in cryogenically cooled refrigerators is discussed. Low-power Stirling cryocoolers; spacecraft-borne long-life units; heat exchangers; performance tests; split-stirling, linear-resonant, cryogenic refrigerators; and computer models are among the topics discussed.

  8. Reliability Estimation When a Test Is Split into Two Parts of Unknown Effective Length.

    ERIC Educational Resources Information Center

    Feldt, Leonard S.

    2002-01-01

    Considers the situation in which content or administrative considerations limit the way in which a test can be partitioned to estimate the internal consistency reliability of the total test score. Demonstrates that a single-valued estimate of the total score reliability is possible only if an assumption is made about the comparative size of the…

  9. Complex Anisotropic Structure of the Mantle Wedge Beneath Kamchatka Volcanoes

    NASA Astrophysics Data System (ADS)

    Levin, V.; Park, J.; Gordeev, E.; Droznin, D.

    2002-12-01

    A wedge of mantle material above the subducting lithospheric plate at a convergent margin is among the most dynamic environments of the Earth's interior. Deformation and transport of solid and volatile phases within this region control the fundamental process of elemental exchange between the surficial layers and the interior of the planet. A helpful property in the study of material deformation and transport within the upper mantle is seismic anisotropy, which may reflect both microscopic effects of preferentialy aligned crystals of olivine and orthopyroxene and macroscopic effects of systematic cracks, melt lenses, layering etc. Through the mapping of anisotropic properties within the mantle wedge we can establish patterns of deformation. Volatile content affects olivine alignment, so regions of anomalous volatile content may be evident. Indicators of seismic anisotropy commonly employed in upper mantle studies include shear wave birefringence and mode-conversion between compressional and shear body waves. When combined together, these techniques offer complementary constraints on the location and intensity of anisotropic properties. The eastern coast of southern Kamchatka overlies a vigorous convergent margin where the Pacific plate descends at a rate of almost 80 mm/yr towards the northwest. We extracted seismic anisotropy indicators from two data sets sensitive to the anisotropic properties of the uppermost mantle. Firstly, we evaluated teleseismic receiver functions for a number of sites, and found ample evidence for anisotropicaly-influenced P-to-S mode conversion. Secondly, we measured splitting in S waves of earthquakes with sources within the downgoing slab. The first set of observations provides constraints on the depth ranges where strong changes in anisotropic properties take place. The local splitting data provides constraints on the cumulative strength of anisotropic properties along specific pathways through the mantle wedge and possibly parts of the slab. To explain the vertical stratification of anisotropy implied from receiver functions, and the strong lateral dependence of shear-wave splitting observations, we cannot rely on simple models of mantle wedge behaviour e.g., olivine-crystal alignment through subduction-driven corner flow. Diverse mechanisms can contribute to the observed pattern of anisotropic properties, with volatiles likely being a key influence. For instance, we find evidence in favor of a slow-symmetry-axis anisotropy within the uppermost 10-20 km of the mantle wedge, implying either excessive hydration of the mantle or else a presence of systematically aligned volatile-filled cracks or lenses. Also, shear-wave splitting is weak beneath the Avachinsky-Koryaksky volcanic center, suggesting either vertical flow or the influence of volatiles and/or thermally-enhanced diffusion creep.

  10. C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis.

    PubMed

    Conroy, Pauline C; Saladino, Chiara; Dantas, Tiago J; Lalor, Pierce; Dockery, Peter; Morrison, Ciaran G

    2012-10-15

    Cilia are found on most human cells and exist as motile cilia or non-motile primary cilia. Primary cilia play sensory roles in transducing various extracellular signals, and defective ciliary functions are involved in a wide range of human diseases. Centrosomes are the principal microtubule-organizing centers of animal cells and contain two centrioles. We observed that DNA damage causes centriole splitting in non-transformed human cells, with isolated centrioles carrying the mother centriole markers CEP170 and ninein but not kizuna or cenexin. Loss of centriole cohesion through siRNA depletion of C-NAP1 or rootletin increased radiation-induced centriole splitting, with C-NAP1-depleted isolated centrioles losing mother markers. As the mother centriole forms the basal body in primary cilia, we tested whether centriole splitting affected ciliogenesis. While irradiated cells formed apparently normal primary cilia, most cilia arose from centriolar clusters, not from isolated centrioles. Furthermore, C-NAP1 or rootletin knockdown reduced primary cilium formation. Therefore, the centriole cohesion apparatus at the proximal end of centrioles may provide a target that can affect primary cilium formation as part of the DNA damage response.

  11. MIP models and hybrid algorithms for simultaneous job splitting and scheduling on unrelated parallel machines.

    PubMed

    Eroglu, Duygu Yilmaz; Ozmutlu, H Cenk

    2014-01-01

    We developed mixed integer programming (MIP) models and hybrid genetic-local search algorithms for the scheduling problem of unrelated parallel machines with job sequence and machine-dependent setup times and with job splitting property. The first contribution of this paper is to introduce novel algorithms which make splitting and scheduling simultaneously with variable number of subjobs. We proposed simple chromosome structure which is constituted by random key numbers in hybrid genetic-local search algorithm (GAspLA). Random key numbers are used frequently in genetic algorithms, but it creates additional difficulty when hybrid factors in local search are implemented. We developed algorithms that satisfy the adaptation of results of local search into the genetic algorithms with minimum relocation operation of genes' random key numbers. This is the second contribution of the paper. The third contribution of this paper is three developed new MIP models which are making splitting and scheduling simultaneously. The fourth contribution of this paper is implementation of the GAspLAMIP. This implementation let us verify the optimality of GAspLA for the studied combinations. The proposed methods are tested on a set of problems taken from the literature and the results validate the effectiveness of the proposed algorithms.

  12. Sampling for mercury at subnanogram per litre concentrations for load estimation in rivers

    USGS Publications Warehouse

    Colman, J.A.; Breault, R.F.

    2000-01-01

    Estimation of constituent loads in streams requires collection of stream samples that are representative of constituent concentrations, that is, composites of isokinetic multiple verticals collected along a stream transect. An all-Teflon isokinetic sampler (DH-81) cleaned in 75??C, 4 N HCl was tested using blank, split, and replicate samples to assess systematic and random sample contamination by mercury species. Mean mercury concentrations in field-equipment blanks were low: 0.135 ng??L-1 for total mercury (??Hg) and 0.0086 ng??L-1 for monomethyl mercury (MeHg). Mean square errors (MSE) for ??Hg and MeHg duplicate samples collected at eight sampling stations were not statistically different from MSE of samples split in the laboratory, which represent the analytical and splitting error. Low fieldblank concentrations and statistically equal duplicate- and split-sample MSE values indicate that no measurable contamination was occurring during sampling. Standard deviations associated with example mercury load estimations were four to five times larger, on a relative basis, than standard deviations calculated from duplicate samples, indicating that error of the load determination was primarily a function of the loading model used, not of sampling or analytical methods.

  13. Pre-stack separation of PP and split PS waves in HTI media

    NASA Astrophysics Data System (ADS)

    Lu, Jun; Wang, Yun; Yang, Yuyong; Chen, Jingyi

    2017-07-01

    Separation of PP and split PS waves in transversely isotropic media with a horizontal axis of symmetry is crucial for imaging subsurface targets and for fracture prediction in a multicomponent seismic survey using P-wave sources. In conventional multicomponent processing, when a low velocity zone is present near the surface, it is often assumed that the vertical Z-component mainly records P modes and that the horizontal X- and Y-components record S modes, including split PS waves. However, this assumption does not hold when the ubiquitous presence of azimuthal anisotropy makes near surface velocity structures more complicated. Seismic wavefields recorded in each component therefore generally represent a complex waveform formed by PP and split PS waves, seriously distorting velocity analysis and seismic imaging. Most previous studies on wave separation have tended to separate P and S modes using pre-stack data and to separate split S modes using post-stack sections, under the assumption of orthogonal polarization. However, split S modes can hardly maintain their original orthogonal polarizations during propagation to the surface due to stratigraphic heterogeneity. Here, without assuming orthogonal polarization, we present a method for pre-stack separation of PP, PS1 and PS2 waves using all three components. The core of our method is the rotation of wave vectors from the Cartesian coordinate system established by Z-, R- and T-axes to a coordinate system established by the true PP-, PS1- and PS2-wave vector directions. Further, we propose a three-component superposition approach to obtain base wave vectors for the coordinate system transformation. Synthetic data testing results confirm that the performance of our wave separation method is stable under different noise levels. Application to field data from Southwest China reveals the potential of our proposed method.

  14. Can short-term oral fine motor training affect precision of task performance and induce cortical plasticity of the jaw muscles?

    PubMed

    Zhang, Hong; Kumar, Abhishek; Kothari, Mohit; Luo, Xiaoping; Trulsson, Mats; Svensson, Krister G; Svensson, Peter

    2016-07-01

    The aim was to test the hypothesis that short-term oral sensorimotor training of the jaw muscles would increase the precision of task performance and induce neuroplastic changes in the corticomotor pathways, related to the masseter muscle. Fifteen healthy volunteers performed six series with ten trials of an oral sensorimotor task. The task was to manipulate and position a spherical chocolate candy in between the anterior teeth and split it into two equal halves. The precision of the task performance was evaluated by comparing the ratio between the two split halves. A series of "hold-and-split" tasks was also performed before and after the training. The hold force and split force along with the electromyographic (EMG) activity of jaw muscles were recorded. Motor-evoked potentials and cortical motor maps of the right masseter muscle were evoked by transcranial magnetic stimulation. There was a significant effect of series on the precision of the task performance during the short-term oral sensorimotor training (P < 0.002). The hold force during the "hold-and-split" task was significantly lower after training than before the short-term training (P = 0.011). However, there was no change in the split force and the EMG activity of the jaw muscles before and after the training. Further, there was a significant increase in the amplitude of the motor-evoked potentials (P < 0.016) and in the motor cortex map areas (P = 0.033), after the short-term oral sensorimotor training. Therefore, short-term oral sensorimotor task training increased the precision of task performance and induced signs of neuroplastic changes in the corticomotor pathways, related to the masseter muscle.

  15. Finite frequency shear wave splitting tomography: a model space search approach

    NASA Astrophysics Data System (ADS)

    Mondal, P.; Long, M. D.

    2017-12-01

    Observations of seismic anisotropy provide key constraints on past and present mantle deformation. A common method for upper mantle anisotropy is to measure shear wave splitting parameters (delay time and fast direction). However, the interpretation is not straightforward, because splitting measurements represent an integration of structure along the ray path. A tomographic approach that allows for localization of anisotropy is desirable; however, tomographic inversion for anisotropic structure is a daunting task, since 21 parameters are needed to describe general anisotropy. Such a large parameter space does not allow a straightforward application of tomographic inversion. Building on previous work on finite frequency shear wave splitting tomography, this study aims to develop a framework for SKS splitting tomography with a new parameterization of anisotropy and a model space search approach. We reparameterize the full elastic tensor, reducing the number of parameters to three (a measure of strength based on symmetry considerations for olivine, plus the dip and azimuth of the fast symmetry axis). We compute Born-approximation finite frequency sensitivity kernels relating model perturbations to splitting intensity observations. The strong dependence of the sensitivity kernels on the starting anisotropic model, and thus the strong non-linearity of the inverse problem, makes a linearized inversion infeasible. Therefore, we implement a Markov Chain Monte Carlo technique in the inversion procedure. We have performed tests with synthetic data sets to evaluate computational costs and infer the resolving power of our algorithm for synthetic models with multiple anisotropic layers. Our technique can resolve anisotropic parameters on length scales of ˜50 km for realistic station and event configurations for dense broadband experiments. We are proceeding towards applications to real data sets, with an initial focus on the High Lava Plains of Oregon.

  16. Use of an Electrochemical Split Cell Technique to Evaluate the Influence of Shewanella oneidensis Activities on Corrosion of Carbon Steel

    PubMed Central

    Miller, Robert Bertram; Sadek, Anwar; Rodriguez, Alvaro; Iannuzzi, Mariano; Giai, Carla; Senko, John M.; Monty, Chelsea N.

    2016-01-01

    Microbially induced corrosion (MIC) is a complex problem that affects various industries. Several techniques have been developed to monitor corrosion and elucidate corrosion mechanisms, including microbiological processes that induce metal deterioration. We used zero resistance ammetry (ZRA) in a split chamber configuration to evaluate the effects of the facultatively anaerobic Fe(III) reducing bacterium Shewanella oneidensis MR-1 on the corrosion of UNS G10180 carbon steel. We show that activities of S. oneidensis inhibit corrosion of steel with which that organism has direct contact. However, when a carbon steel coupon in contact with S. oneidensis was electrically connected to a second coupon that was free of biofilm (in separate chambers of the split chamber assembly), ZRA-based measurements indicated that current moved from the S. oneidensis-containing chamber to the cell-free chamber. This electron transfer enhanced the O2 reduction reaction on the coupon deployed in the cell free chamber, and consequently, enhanced oxidation and corrosion of that electrode. Our results illustrate a novel mechanism for MIC in cases where metal surfaces are heterogeneously covered by biofilms. PMID:26824529

  17. Positive pacing in elite IRONMAN triathletes.

    PubMed

    Angehrn, Nicole; Rüst, Christoph A.; Nikolaidis, Pantelis T.; Rosemann, Thomas; Knechtle, Beat

    2016-12-31

    Pacing is known to influence athletic performance. For the Ironman triathlon program, a positive pacing strategy, i.e., the continuous decrease of speed over time was recommended. By analyzing split times, we assessed the pacing strategies of the top 100 finishers of the cycling part of 13 Ironman races and of the running part of 11 Ironman races taking place in 2014. Furthermore, sex-associated differences in performance and pacing strategies were calculated. We analyzed 7,687 cycling and 11,894 running split times of 1,392 triathletes (1,263 men, 129 women). Changes in speed were assessed using mixed-effects regression analyses. A continuous decrease in speed was observed during cycling in 10/13 races, and during running in 11/11 races. In 6/13 races, women decreased their speed during cycling significantly more than men. The running part showed no significant difference of changes in speed between the sexes. In summary, in the Ironman races evaluated, a positive pacing strategy was adopted in most races. Women were slower than men in 6/13 cycling races, but there was no difference between men and women in the run splits. Women used the same pacing strategy as men.

  18. Predicting human decisions in socioeconomic interaction using real-time functional magnetic resonance imaging (rtfMRI)

    NASA Astrophysics Data System (ADS)

    Hollmann, Maurice; Mönch, Tobias; Müller, Charles; Bernarding, Johannes

    2009-02-01

    A major field in cognitive neuroscience investigates neuronal correlates of human decision-making processes [1, 2]. Is it possible to predict a decision before it is actually revealed by the volunteer? In the presented manuscript we use a standard paradigm from economic behavioral research that proved emotional influences on human decision making: the Ultimatum Game (UG). In the UG, two players have the opportunity to split a sum of money. One player is deemed the proposer and the other, the responder. The proposer makes an offer as to how this money should be split between the two. The second player can either accept or reject this offer. If it is accepted, the money is split as proposed. If rejected, then neither player receives anything. In the presented study a real-time fMRI system was used to derive the brain activation of the responder. Using a Relevance-Vector-Machine classifier it was possible to predict if the responder will accept or reject an offer. The classification result was presented to the operator 1-2 seconds before the volunteer pressed a button to convey his decision. The classification accuracy reached about 70% averaged over six subjects.

  19. Density Functional Theory Simulations of Water Adsorption and Activation on the (-201) β-Ga2 O3 Surface.

    PubMed

    Anvari, Roozbeh; Spagnoli, Dino; Parish, Giacinta; Nener, Brett

    2018-03-09

    Density functional theory calculations are used to study the molecular and dissociative adsorption of water on the (-201) β-Ga 2 O 3 surface. The effect of adsorption of different water-like species on the geometry, binding energies, vibrational spectra and the electronic structure of the surface are discussed. The study shows that although the hydrogen evolution reaction requires a small amount of energy to become energetically favourable, the over potential for activating the oxygen evolution reaction is quite high. The results of our calculations provide insight as to why a high voltage is required in experiments to activate the water-splitting reaction, whereas previous studies of gallium oxide predicted very low activation energies for other energetically more favourable facets. Application of this work to studies of GaN-based chemical sensors with gallium oxide surfaces shows that it is possible to select the gate bias so that the sensors are not influenced by water-splitting reactions. It was also found that in the region where water splitting does not occur, the surface can exist in two states, that is, water or hydroxyl terminated. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Reliability and validity of the revised Gibson Test of Cognitive Skills, a computer-based test battery for assessing cognition across the lifespan.

    PubMed

    Moore, Amy Lawson; Miller, Terissa M

    2018-01-01

    The purpose of the current study is to evaluate the validity and reliability of the revised Gibson Test of Cognitive Skills, a computer-based battery of tests measuring short-term memory, long-term memory, processing speed, logic and reasoning, visual processing, as well as auditory processing and word attack skills. This study included 2,737 participants aged 5-85 years. A series of studies was conducted to examine the validity and reliability using the test performance of the entire norming group and several subgroups. The evaluation of the technical properties of the test battery included content validation by subject matter experts, item analysis and coefficient alpha, test-retest reliability, split-half reliability, and analysis of concurrent validity with the Woodcock Johnson III Tests of Cognitive Abilities and Tests of Achievement. Results indicated strong sources of evidence of validity and reliability for the test, including internal consistency reliability coefficients ranging from 0.87 to 0.98, test-retest reliability coefficients ranging from 0.69 to 0.91, split-half reliability coefficients ranging from 0.87 to 0.91, and concurrent validity coefficients ranging from 0.53 to 0.93. The Gibson Test of Cognitive Skills-2 is a reliable and valid tool for assessing cognition in the general population across the lifespan.

  1. Evaluation of Fiber Reinforced Cement Using Digital Image Correlation

    PubMed Central

    Melenka, Garrett W.; Carey, Jason P.

    2015-01-01

    The effect of short fiber reinforcements on the mechanical properties of cement has been examined using a splitting tensile – digital image correlation (DIC) measurement method. Three short fiber reinforcement materials have been used in this study: fiberglass, nylon, and polypropylene. The method outlined provides a simple experimental setup that can be used to evaluate the ultimate tensile strength of brittle materials as well as measure the full field strain across the surface of the splitting tensile test cylindrical specimen. Since the DIC measurement technique is a contact free measurement this method can be used to assess sample failure. PMID:26039590

  2. Impact behaviour of freeze-dried and fresh pomelo (Citrus maxima) peel: influence of the hydration state

    PubMed Central

    Thielen, Marc; Speck, Thomas; Seidel, Robin

    2015-01-01

    Pomelos (Citrus maxima) are known for their thick peel which—inter alia—serves as energy dissipator when fruits impact on the ground after being shed. It protects the fruit from splitting open and thus enables the contained seeds to stay germinable and to potentially be dispersed by animal vectors. The main part of the peel consists of a parenchymatous tissue that can be interpreted from a materials point of view as open pored foam whose struts are pressurized and filled with liquid. In order to investigate the influence of the water content on the energy dissipation capacity, drop weight tests were conducted with fresh and with freeze-dried peel samples. Based on the coefficient of restitution it was found that freeze-drying markedly reduces the relative energy dissipation capacity of the peel. Measuring the transmitted force during impact furthermore indicated a transition from a uniform collapse of the foam-like tissue to a progressive collapse due to water extraction. Representing the peel by a Maxwell model illustrates that freeze-drying not only drastically reduces the damping function of the dashpots but also stiffens the springs of the model. PMID:26543566

  3. Influence of Fermentation and Drying Materials on the Contamination of Cocoa Beans by Ochratoxin A

    PubMed Central

    Dano, Sébastien Djédjé; Manda, Pierre; Dembélé, Ardjourma; Abla, Ange Marie-Joseph Kouassi; Bibaud, Joel Henri; Gouet, Julien Zroh; Sika, Charles Bruno Ze Maria

    2013-01-01

    Ochratoxin A (OTA) is a mycotoxin produced mainly by species of Aspergillus and Penicillium. Contamination of food with OTA is a major consumer health hazard. In Côte d’Ivoire, preventing OTA contamination has been the subject of extensive study. The current study was conducted to evaluate the influence of fermentation and drying materials on the OTA content in cocoa. For each test, 7000 intact cocoa pods were collected, split open to remove the beans, fermented using 1 of 3 different materials, sun-dried on 1 of 3 different platform types and stored for 30 days. A total of 22 samples were collected at each stage of post-harvesting operations. The OTA content in the extracted samples was then quantified by high-performance liquid chromatography. OTA was detected in beans at all stages of post-harvesting operations at varying levels: pod-opening (0.025 ± 0.02 mg/kg), fermentation (0.275 ± 0.2 mg/kg), drying (0.569 ± 0.015 mg/kg), and storage (0.558 ± 0.04 mg/kg). No significant relationships between the detected OTA level and the materials used in the fermentation and drying of cocoa were observed. PMID:24287569

  4. Multiple Graft Harvestings from Deep Partial-Thickness Scald Wounds Healed under the Influence of Weak Direct Current

    DTIC Science & Technology

    1990-01-01

    acanthosis (H&E, 10X). FIG. 8. Scald wound of a treated animal 16 days after the second split-thickness skin graft harvesting. A) Gross appearance...that is, simply cutting the skin graft at a prede- Doctor Monafo’s questions about another model: yes, in fact, termined thickness and then

  5. The Developmental Influence of Primary Memory Capacity on Working Memory and Academic Achievement

    ERIC Educational Resources Information Center

    Hall, Debbora; Jarrold, Christopher; Towse, John N.; Zarandi, Amy L.

    2015-01-01

    In this study, we investigate the development of primary memory capacity among children. Children between the ages of 5 and 8 completed 3 novel tasks (split span, interleaved lists, and a modified free-recall task) that measured primary memory by estimating the number of items in the focus of attention that could be spontaneously recalled in…

  6. Variable response by aquatic invertebrates to experimental manipulations of leaf litter input into seasonal woodland ponds

    Treesearch

    Darold P. Batzer; Brian J. Palik

    2007-01-01

    Aquatic invertebrates are crucial components of foodwebs in seasonal woodland ponds, and leaf litter is probably the most important food resource for those organisms. We quantified the influence of leaf litter inputs on aquatic invertebrates in two seasonal woodland ponds using an interception experiment. Ponds were hydrologically split using a sandbag-plastic barrier...

  7. Elastic solitons in delaminated bars: splitting leads to fission

    NASA Astrophysics Data System (ADS)

    Samsonov, A. M.; Dreiden, G. V.; Khusnutdinova, K. R.; Semenova, I. V.

    2008-06-01

    Recent theoretical and successful experimental studies confirmed existence and demonstrated main properties of bulk strain solitary waves in nonlinearly elastic solid wave guides. Our current research is devoted to nonlinear wave processes in layered elastic wave guides with inhomogeneities modelling delamination. We present first theoretical and experimental results showing the influence of delamination on the parameters of the longitudinal strain solitary wave.

  8. Female dispersal, social organization, and infanticide in langurs: are they linked to human disturbance?

    PubMed

    Sterck, E H

    1998-01-01

    Female dispersal in gregarious animals can involve the desertion of a site, desertion of a social group, or both. Group desertion may be related to inbreeding avoidance. Group fidelity may result from cooperation among females in a group. Site fidelity will be more likely when food can be monopolized and when the population density is close to habitat saturation. The degree of habitat saturation was approximated with a measure of human disturbance. The influence of these various factors on the incidence of female dispersal was investigated for langur populations using data from the literature. The results suggest that female dispersal in langurs involved site desertion, not group desertion. The incidence of female dispersal may affect the social organization of langurs. I propose that when females do not disperse, male takeovers prevail, whereas in populations where female dispersal regularly occurs bisexual groups are disbanded or new groups are formed, a process I call female split-merger. Male takeover is thought to occur when site fidelity is high, female split-merger when site fidelity is low. These processes were indeed found to occur in these circumstances. The dispersal of females might prevent infanticide, whereas male takeover might promote it. Indeed, in studies with male takeover, more infants fell victim to infanticide than in studies with female split-merger. Therefore, female dispersal in langurs is an effective female counterstrategy to infanticide. The factor that had the most profound effect on female dispersal, social organization, and infanticide was habitat saturation. Habitat saturation was measured as the degree of human disturbance, and its influence on the behavior of langurs is probably of relatively recent date. This may lead to an evolutionary transient situation and may explain the discrepancy between current socioecological theories and the behavior of langurs in populations lacking female dispersal.

  9. Influence of heat losses on nonlinear fingering dynamics of exothermic autocatalytic fronts

    NASA Astrophysics Data System (ADS)

    D'Hernoncourt, J.; De Wit, A.

    2010-06-01

    Across traveling exothermic autocatalytic fronts, a density jump can be observed due to changes in composition and temperature. These density changes are prone to induce buoyancy-driven convection around the front when the propagation takes place in absence of gel within the gravity field. Most recent experiments devoted to studying such reaction-diffusion-convection dynamics are performed in Hele-Shaw cells, two glass plates separated by a thin gap width and filled by the chemical solutions. We investigate here the influence of heat losses through the walls of such cells on the nonlinear fingering dynamics of exothermic autocatalytic fronts propagating in vertical Hele-Shaw cells. We show that these heat losses increase tip splittings and modify the properties of the flow field. A comparison of the differences between the dynamics in reactors with respectively insulating and conducting walls is performed as a function of the Lewis number Le, the Newton cooling coefficient α quantifying the amplitude of heat losses and the width of the system. We find that tip splitting is enhanced for intermediate values of α while coarsening towards one single finger dominates for insulated systems or large values of α leading to situations equivalent to isothermal ones.

  10. [Influence of personality traits on reaction performance in volunteers after a single administration of placebo, crotylbarbital and caffeine].

    PubMed

    Meyer, F P; Walther, T; Walther, H

    1983-01-01

    We examined the influence of single applications of placebo, caffeine (7 mg/kg), and crotylbarbital (2 mg/kg) on reaction and attention performance in 15 volunteers. A newly developed reaction-time apparatus permits the reaction time to be split for differentiation between initiation time and movement time. Moreover, simple and complex attention performance can be quantified. The volunteers were selected as to the dimensions of "introversion/extraversion" and "emotional lability/stability" by means of the Freiburg Personality Inventory. Labile volunteers responded to placebo faster than stables. Caffeine improved mainly the performance of introverted subjects. Crotylbarbital was without influence on the reaction time at the threshold dose applied.

  11. 49 CFR 192.717 - Transmission lines: Permanent field repair of leaks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... encirclement welded split sleeve of appropriate design, unless the transmission line is joined by mechanical... method that reliable engineering tests and analyses show can permanently restore the serviceability of...

  12. 49 CFR 192.717 - Transmission lines: Permanent field repair of leaks.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... encirclement welded split sleeve of appropriate design, unless the transmission line is joined by mechanical... method that reliable engineering tests and analyses show can permanently restore the serviceability of...

  13. 49 CFR 192.717 - Transmission lines: Permanent field repair of leaks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... encirclement welded split sleeve of appropriate design, unless the transmission line is joined by mechanical... method that reliable engineering tests and analyses show can permanently restore the serviceability of...

  14. 49 CFR 192.717 - Transmission lines: Permanent field repair of leaks.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... encirclement welded split sleeve of appropriate design, unless the transmission line is joined by mechanical... method that reliable engineering tests and analyses show can permanently restore the serviceability of...

  15. Quantum-chemical prediction of the effects of Ni-loading on the hydrogenation and water-splitting efficiency of TiO2 nanoparticles with an experimental test

    NASA Astrophysics Data System (ADS)

    Lin, Cheng-Kuo; Chuang, Chung-Ching; Raghunath, Putikam; Srinivasadesikan, V.; Wang, T. T.; Lin, M. C.

    2017-01-01

    The effects of Ni-loading on TiO2 nanoparticles can pronouncedly reduce the barriers for dissociation of H2 from 48 kcal/mol on the pure TiO2 to as low as 1-3 kcal/mol on the loaded samples facilitating the hydrogenation of NPs. Preliminary data of our test indicate that the hydrogenation of Ni-loaded TiO2 NPs results in a significant UV-visible absorption extending well beyond 750 nm with an increase in water splitting efficiency by as much as 67 times over those of pure and hydrogenated TiO2 NPs without Ni-loading under our mild hydrogenation condition using 800 Torr of H2 at 300 °C for 3 h.

  16. Modeling for influenza vaccines and adjuvants profile for safety prediction system using gene expression profiling and statistical tools

    PubMed Central

    Sasaki, Eita; Momose, Haruka; Hiradate, Yuki; Furuhata, Keiko; Takai, Mamiko; Asanuma, Hideki; Ishii, Ken J.

    2018-01-01

    Historically, vaccine safety assessments have been conducted by animal testing (e.g., quality control tests and adjuvant development). However, classical evaluation methods do not provide sufficient information to make treatment decisions. We previously identified biomarker genes as novel safety markers. Here, we developed a practical safety assessment system used to evaluate the intramuscular, intraperitoneal, and nasal inoculation routes to provide robust and comprehensive safety data. Influenza vaccines were used as model vaccines. A toxicity reference vaccine (RE) and poly I:C-adjuvanted hemagglutinin split vaccine were used as toxicity controls, while a non-adjuvanted hemagglutinin split vaccine and AddaVax (squalene-based oil-in-water nano-emulsion with a formulation similar to MF59)-adjuvanted hemagglutinin split vaccine were used as safety controls. Body weight changes, number of white blood cells, and lung biomarker gene expression profiles were determined in mice. In addition, vaccines were inoculated into mice by three different administration routes. Logistic regression analyses were carried out to determine the expression changes of each biomarker. The results showed that the regression equations clearly classified each vaccine according to its toxic potential and inoculation amount by biomarker expression levels. Interestingly, lung biomarker expression was nearly equivalent for the various inoculation routes. The results of the present safety evaluation were confirmed by the approximation rate for the toxicity control. This method may contribute to toxicity evaluation such as quality control tests and adjuvant development. PMID:29408882

  17. Processes and Procedures for Estimating Score Reliability and Precision

    ERIC Educational Resources Information Center

    Bardhoshi, Gerta; Erford, Bradley T.

    2017-01-01

    Precision is a key facet of test development, with score reliability determined primarily according to the types of error one wants to approximate and demonstrate. This article identifies and discusses several primary forms of reliability estimation: internal consistency (i.e., split-half, KR-20, a), test-retest, alternate forms, interscorer, and…

  18. Leap-frog-based BPM (LF-BPM) method for solving nanophotonic structures

    NASA Astrophysics Data System (ADS)

    Ayoub, Ahmad B.; Swillam, Mohamed A.

    2018-02-01

    In this paper, we propose an efficient approach to solve the BPM equation. By splitting the complex field into real and imaginary parts, the method is proved to be at least 30% faster than the conventional BPM. This method was tested on several optical components to test the accuracy.

  19. Performance test of a grid-tied PV system to power a split air conditioner system in Surabaya

    NASA Astrophysics Data System (ADS)

    Tarigan, E.

    2017-11-01

    Air conditioner for cooling air is one of the major needs for those who live in hot climate area such as Indonesia. This work presents the performance test of a grid-tied PV system to power air conditioner under a hot tropical climate in Surabaya, Indonesia. A 800 WP grid-tied photovoltaic (PV) system was used, and its performance was tested to power a 0.5 pk of split air conditioner system. It was found that about 3.5 kWh daily energy was consumed by the tested air conditioner system, and about 80% it could be supplied from the PV system. While the other 20% was supplied by the grid during periods of low solar irradiation, 440 Wh of energy was fed into the grid during operation out of office hours. By using the grid-tied PV system, the energy production by PV system did not need to match the consumption of the air conditioner. However, a larger capacity of PV system would mean that a higher percentage of the load would be covered by PV system.

  20. First-order symmetry-adapted perturbation theory for multiplet splittings.

    PubMed

    Patkowski, Konrad; Żuchowski, Piotr S; Smith, Daniel G A

    2018-04-28

    We present a symmetry-adapted perturbation theory (SAPT) for the interaction of two high-spin open-shell molecules (described by their restricted open-shell Hartree-Fock determinants) resulting in low-spin states of the complex. The previously available SAPT formalisms, except for some system-specific studies for few-electron complexes, were restricted to the high-spin state of the interacting system. Thus, the new approach provides, for the first time, a SAPT-based estimate of the splittings between different spin states of the complex. We have derived and implemented the lowest-order SAPT term responsible for these splittings, that is, the first-order exchange energy. We show that within the so-called S 2 approximation commonly used in SAPT (neglecting effects that vanish as fourth or higher powers of intermolecular overlap integrals), the first-order exchange energies for all multiplets are linear combinations of two matrix elements: a diagonal exchange term that determines the spin-averaged effect and a spin-flip term responsible for the splittings between the states. The numerical factors in this linear combination are determined solely by the Clebsch-Gordan coefficients: accordingly, the S 2 approximation implies a Heisenberg Hamiltonian picture with a single coupling strength parameter determining all the splittings. The new approach is cast into both molecular-orbital and atomic-orbital expressions: the latter enable an efficient density-fitted implementation. We test the newly developed formalism on several open-shell complexes ranging from diatomic systems (Li⋯H, Mn⋯Mn, …) to the phenalenyl dimer.

  1. First-order symmetry-adapted perturbation theory for multiplet splittings

    NASA Astrophysics Data System (ADS)

    Patkowski, Konrad; Żuchowski, Piotr S.; Smith, Daniel G. A.

    2018-04-01

    We present a symmetry-adapted perturbation theory (SAPT) for the interaction of two high-spin open-shell molecules (described by their restricted open-shell Hartree-Fock determinants) resulting in low-spin states of the complex. The previously available SAPT formalisms, except for some system-specific studies for few-electron complexes, were restricted to the high-spin state of the interacting system. Thus, the new approach provides, for the first time, a SAPT-based estimate of the splittings between different spin states of the complex. We have derived and implemented the lowest-order SAPT term responsible for these splittings, that is, the first-order exchange energy. We show that within the so-called S2 approximation commonly used in SAPT (neglecting effects that vanish as fourth or higher powers of intermolecular overlap integrals), the first-order exchange energies for all multiplets are linear combinations of two matrix elements: a diagonal exchange term that determines the spin-averaged effect and a spin-flip term responsible for the splittings between the states. The numerical factors in this linear combination are determined solely by the Clebsch-Gordan coefficients: accordingly, the S2 approximation implies a Heisenberg Hamiltonian picture with a single coupling strength parameter determining all the splittings. The new approach is cast into both molecular-orbital and atomic-orbital expressions: the latter enable an efficient density-fitted implementation. We test the newly developed formalism on several open-shell complexes ranging from diatomic systems (Li⋯H, Mn⋯Mn, …) to the phenalenyl dimer.

  2. Scale for positive aspects of caregiving experience: development, reliability, and factor structure.

    PubMed

    Kate, N; Grover, S; Kulhara, P; Nehra, R

    2012-06-01

    OBJECTIVE. To develop an instrument (Scale for Positive Aspects of Caregiving Experience [SPACE]) that evaluates positive caregiving experience and assess its psychometric properties. METHODS. Available scales which assess some aspects of positive caregiving experience were reviewed and a 50-item questionnaire with a 5-point rating was constructed. In all, 203 primary caregivers of patients with severe mental disorders were asked to complete the questionnaire. Internal consistency, test-retest reliability, cross-language reliability, split-half reliability, and face validity were evaluated. Principal component factor analysis was run to assess the factorial validity of the scale. RESULTS. The scale developed as part of the study was found to have good internal consistency, test-retest reliability, cross-language reliability, split-half reliability, and face validity. Principal component factor analysis yielded a 4-factor structure, which also had good test-retest reliability and cross-language reliability. There was a strong correlation between the 4 factors obtained. CONCLUSION. The SPACE developed as part of this study has good psychometric properties.

  3. Full Scale Span Load Distribution on a Tapered Wing with Split Flaps of Various Spans

    NASA Technical Reports Server (NTRS)

    Parsons, John F; Silverstein, Abe

    1937-01-01

    Pressure-distribution tests were conducted in the full-scale wind tunnel on a 2:1 tapered U.S.A. 45 airfoil equipped with 20 percent chord split trailing-edge flaps of various spans. A special installation was employed in the tests utilizing a half-span airfoil mounted vertically above a reflection plane. The airfoil has a constant chord center section and rounded tips and is tapered in thickness from 18 percent c at the root to 9 percent c at the tip. The aerodynamic characteristics, given by the usual dimension less coefficients, are presented graphically as functions of flap span and angle of attack as well as by semispan load diagrams. The results indicate, in general, that only a relatively small increase in the normal-force coefficient is to be expected by extending the flap span of an airfoil-flap combination, similar to the one tested, beyond 70 percent of the wing span.

  4. The 3600 hp split-torque helicopter transmission

    NASA Technical Reports Server (NTRS)

    White, G.

    1985-01-01

    Final design details of a helicopter transmission that is powered by GE twin T 700 engines each rated at 1800 hp are presented. It is demonstrated that in comparison with conventional helicopter transmission arrangements the split torque design offers: weight reduction of 15%; reduction in drive train losses of 9%; and improved reliability resulting from redundant drive paths between the two engines and the main shaft. The transmission fits within the NASA LeRC 3000 hp Test Stand and accepts the existing positions for engine inputs, main shaft, connecting drive shafts, and the cradle attachment points. One necessary change to the test stand involved gear trains of different ratio in the tail drive gearbox. Progressive uprating of engine input power from 3600 to 4500 hp twin engine rating is allowed for in the design. In this way the test transmission will provide a base for several years of analytical, research, and component development effort targeted at improving the performance and reliability of helicopter transmission.

  5. A regional test of global models for flow, rheology, and seismic anisotropy at the base of the mantle

    NASA Astrophysics Data System (ADS)

    Ford, Heather A.; Long, Maureen D.

    2015-08-01

    The study of flow patterns and seismic anisotropy in the lowermost mantle is fraught with uncertainties, given the limitations in our understanding of the physical properties of the lowermost mantle and the relationships between deformation and anisotropy. Here we use a set of SKS, SKKS, and ScS splitting measurements that sample the eastern edge of the African Large Low Shear Velocity Province to test predictions of seismic anisotropy derived from previously published 3D global mantle flow models and anisotropy modeling (Walker et al., 2011). The observations can be fit by a model that invokes flow directed to the southwest with a component of downwelling in our study region, and slip that occurs along the (0 1 0) plane of post-perovskite. Most importantly, we demonstrate the ability of a regional shear wave splitting data set to test the robustness of models for flow and deformation in the lowermost mantle.

  6. La Saturated Absorption Spectroscopy for Applications in Quantum Information

    NASA Astrophysics Data System (ADS)

    Becker, Patrick; Donoghue, Liz; Dungan, Kristina; Liu, Jackie; Olmschenk, Steven

    2015-05-01

    Quantum information may revolutionize computation and communication by utilizing quantum systems based on matter quantum bits and entangled light. Ions are excellent candidates for quantum bits as they can be well-isolated from unwanted external influences by trapping and laser cooling. Doubly-ionized lanthanum in particular shows promise for use in quantum information as it has infrared transitions in the telecom band, with low attenuation in standard optical fiber, potentially allowing for long distance information transfer. However, the hyperfine splittings of the lowest energy levels, required for laser cooling, have not been measured. We present progress and recent results towards measuring the hyperfine splittings of these levels in lanthanum by saturated absorption spectroscopy with a hollow cathode lamp. This research is supported by the Army Research Office, Research Corporation for Science Advancement, and Denison University.

  7. Meson-meson scattering: K{anti K}-thresholds and f{sub 0}(980)-a{sub 0}(980) mixing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    O. Krehl; R. Rapp; J. Speth

    1996-09-01

    The authors study the influence of mass splitting between the charged and neutral pions and kaons in the Juelich meson exchange model for {pi}{pi} and {pi}{eta} scattering. The calculations are performed in the particle basis, which permits the use of physical masses for the pseudoscalar mesons and a study of the distinct thresholds associated with the neutral and the charged kaons. Within this model the authors also investigate the isospin violation which arises from the mass splitting and an apparent violation of G-parity in {pi}{pi} scattering which stems from the coupling to the K{anti K} channel. Nonvanishing cross sections formore » {pi}{pi} {r_arrow} {pi}{sup 0}{eta} indicate a mixing of the f{sub 0}(980) and a{sub 0}(980) states.« less

  8. In Vitro Plant Regeneration from Commercial Cultivars of Soybean

    PubMed Central

    Raza, Ghulam; Singh, Mohan B.

    2017-01-01

    Soybean, a major legume crop, is the source of vegetable oil and protein. There is a need for transgenic approaches to breeding superior soybean varieties to meet future climate challenges. Efficient plant regeneration is a prerequisite for successful application of genetic transformation technology. Soybean cultivars are classified into different maturity groups based on photoperiod requirements. In this study, nine soybean varieties belonging to different maturity group were regenerated successfully from three different explants: half split hypocotyl, complete hypocotyl, and cotyledonary node. All the genotypes and explant types responded by producing adventitious shoots. Shoot induction potential ranged within 60–87%, 50–100%, and 75–100%, and regeneration rate ranged within 4.2–10, 2.7–4.2, and 2.6–10.5 shoots per explant using half split hypocotyl, complete hypocotyl, and cotyledonary explants, respectively, among all the tested genotypes. Bunya variety showed the best regeneration response using half split and complete hypocotyl explants and the PNR791 with cotyledonary node. The regenerated shoots were successfully rooted and acclimatized to glasshouse conditions. This study shows that commercial varieties of soybean are amenable to shoot regeneration with high regeneration frequencies and could be exploited for genetic transformation. Further, our results show no correlation between shoots regeneration capacity with the maturity grouping of the soybean cultivars tested. PMID:28691031

  9. Single-stage experimental evaluation of tandem-airfoil rotor and stator blading for compressors, part 8

    NASA Technical Reports Server (NTRS)

    Brent, J. A.; Clemmons, D. R.

    1974-01-01

    An experimental investigation was conducted with an 0.8 hub/tip ratio, single-stage, axial flow compressor to determine the potential of tandem-airfoil blading for improving the efficiency and stable operating range of compressor stages. The investigation included testing of a baseline stage with single-airfoil blading and two tandem-blade stages. The overall performance of the baseline stage and the tandem-blade stage with a 20-80% loading split was considerably below the design prediction. The other tandem-blade stage, which had a rotor with a 50-50% loading split, came within 4.5% of the design pressure rise (delta P(bar)/P(bar) sub 1) and matched the design stage efficiency. The baseline stage with single-airfoil blading, which was designed to account for the actual rotor inlet velocity profile and the effects of axial velocity ratio and secondary flow, achieved the design predicted performance. The corresponding tandem-blade stage (50-50% loading split in both blade rows) slightly exceeded the design pressure rise but was 1.5 percentage points low in efficiency. The tandem rotors tested during both phases demonstrated higher pressure rise and efficiency than the corresponding single-airfoil rotor, with identical inlet and exit airfoil angles.

  10. Highly Parallel Alternating Directions Algorithm for Time Dependent Problems

    NASA Astrophysics Data System (ADS)

    Ganzha, M.; Georgiev, K.; Lirkov, I.; Margenov, S.; Paprzycki, M.

    2011-11-01

    In our work, we consider the time dependent Stokes equation on a finite time interval and on a uniform rectangular mesh, written in terms of velocity and pressure. For this problem, a parallel algorithm based on a novel direction splitting approach is developed. Here, the pressure equation is derived from a perturbed form of the continuity equation, in which the incompressibility constraint is penalized in a negative norm induced by the direction splitting. The scheme used in the algorithm is composed of two parts: (i) velocity prediction, and (ii) pressure correction. This is a Crank-Nicolson-type two-stage time integration scheme for two and three dimensional parabolic problems in which the second-order derivative, with respect to each space variable, is treated implicitly while the other variable is made explicit at each time sub-step. In order to achieve a good parallel performance the solution of the Poison problem for the pressure correction is replaced by solving a sequence of one-dimensional second order elliptic boundary value problems in each spatial direction. The parallel code is implemented using the standard MPI functions and tested on two modern parallel computer systems. The performed numerical tests demonstrate good level of parallel efficiency and scalability of the studied direction-splitting-based algorithm.

  11. In Vitro Plant Regeneration from Commercial Cultivars of Soybean.

    PubMed

    Raza, Ghulam; Singh, Mohan B; Bhalla, Prem L

    2017-01-01

    Soybean, a major legume crop, is the source of vegetable oil and protein. There is a need for transgenic approaches to breeding superior soybean varieties to meet future climate challenges. Efficient plant regeneration is a prerequisite for successful application of genetic transformation technology. Soybean cultivars are classified into different maturity groups based on photoperiod requirements. In this study, nine soybean varieties belonging to different maturity group were regenerated successfully from three different explants: half split hypocotyl, complete hypocotyl, and cotyledonary node. All the genotypes and explant types responded by producing adventitious shoots. Shoot induction potential ranged within 60-87%, 50-100%, and 75-100%, and regeneration rate ranged within 4.2-10, 2.7-4.2, and 2.6-10.5 shoots per explant using half split hypocotyl, complete hypocotyl, and cotyledonary explants, respectively, among all the tested genotypes. Bunya variety showed the best regeneration response using half split and complete hypocotyl explants and the PNR791 with cotyledonary node. The regenerated shoots were successfully rooted and acclimatized to glasshouse conditions. This study shows that commercial varieties of soybean are amenable to shoot regeneration with high regeneration frequencies and could be exploited for genetic transformation. Further, our results show no correlation between shoots regeneration capacity with the maturity grouping of the soybean cultivars tested.

  12. Selected laboratory evaluations of the whole-water sample-splitting capabilities of a prototype fourteen-liter Teflon churn splitter

    USGS Publications Warehouse

    Horowitz, A.J.; Smith, J.J.; Elrick, K.A.

    2001-01-01

    A prototype 14-L Teflon? churn splitter was evaluated for whole-water sample-splitting capabilities over a range of sediment concentratons and grain sizes as well as for potential chemical contamination from both organic and inorganic constituents. These evaluations represent a 'best-case' scenario because they were performed in the controlled environment of a laboratory, and used monomineralic silica sand slurries of known concentration made up in deionized water. Further, all splitting was performed by a single operator, and all the requisite concentration analyses were performed by a single laboratory. The prototype Teflon? churn splitter did not appear to supply significant concentrations of either organic or inorganic contaminants at current U.S. Geological Survey (USGS) National Water Quality Laboratory detection and reporting limits when test samples were prepared using current USGS protocols. As with the polyethylene equivalent of the prototype Teflon? churn, the maximum usable whole-water suspended sediment concentration for the prototype churn appears to lie between 1,000 and 10,000 milligrams per liter (mg/L). Further, the maximum grain-size limit appears to lie between 125- and 250-microns (m). Tests to determine the efficacy of the valve baffle indicate that it must be retained to facilitate representative whole-water subsampling.

  13. Electrophysiological study for comparing the effect of biological activity between type A botulinum toxins in rat gastrocnemius muscle.

    PubMed

    Kim, C-S; Jang, W S; Son, I P; Nam, S H; Kim, Y I; Park, K Y; Kim, B J; Kim, M N

    2013-09-01

    New cosmetic applications and products based on the effects of botulinum toxin (BTX) treatment have stimulated demand for this class of natural compounds. This demand generates the need for appropriate standardized protocols to test and compare the effectiveness of new BTX preparations. Based on the previously described electrophysiological methods, we measured and compared the inhibitory effects of two BTX type A (BTX-A) preparations on neuromuscular transmission through split-body test. The effectiveness was evaluated in terms of the compound muscle action potential (CMAP) and conduction velocity after BTX-A injection. We used a split-body method to compare two different BTX-As in the rat. Based on the changes in the CMAP, the two different BTX-As induced paralytic effect on the rat tibialis anterior muscle. However, the two different BTX-A preparations did not differ significantly in effectiveness and did not induce a delay in conduction velocity. The new BTX-A preparation used in this electrophysiological study had similar effect compared with the previously marketed BTX-A.[AQ: Please approve the edits made to the sentence "The new BTX-A preparation…") We propose that a split-body electrophysiological protocol will be useful in establishing the comparative effectiveness of new BTX products.

  14. STELLATE NONHEREDITARY IDIOPATHIC FOVEOMACULAR RETINOSCHISIS ACCOMPANIED BY CONTRALATERAL PERIPHERAL RETINOSCHISIS.

    PubMed

    Ahmed, Daniel; Stattin, Martin; Glittenberg, Carl; Krebs, Ilse; Ansari-Shahrezaei, Siamak

    2017-01-16

    To present a patient with stellate nonhereditary idiopathic foveomacular retinoschisis on one eye and peripheral retinoschisis without foveal affection on the other eye. A case report with complete workup of family history and clinical examination, including multimodal imaging with optical coherence tomography and angiography, fluorescein angiography, and infrared fundus imaging. Genetic testing for gene mutation XRLS1 was performed. A white woman with unremarkable medical history presented with stellate foveal splitting of the outer plexiform layer on the right eye and peripheral splitting of the outer plexiform layer on both eyes. All known allegeable trigger factors for the existence of a hereditary or acquired foveomacular retinoschisis were ruled out either by clinical presentation or genetic testing. This led to the diagnosis of stellate nonhereditary idiopathic foveomacular retinoschisis with central involvement only present on one eye. Although peripheral schisis of the outer plexiform layer is often concomitant with central splitting in X-linked juvenile retinoschisis, this is the first known report of nonhereditary cleavage of the outer plexiform layer of the peripheral retina without central affection in a patient with documented stellate nonhereditary idiopathic foveomacular retinoschisis on the other eye. These findings suggest an accurate bilateral examination of the peripheral retina while confirming the diagnose of stellate nonhereditary idiopathic foveomacular retinoschisis.

  15. Variation in effectiveness of a cardiac auscultation training class with a cardiology patient simulator among heart sounds and murmurs.

    PubMed

    Kagaya, Yutaka; Tabata, Masao; Arata, Yutaro; Kameoka, Junichi; Ishii, Seiichi

    2017-08-01

    Effectiveness of simulation-based education in cardiac auscultation training is controversial, and may vary among a variety of heart sounds and murmurs. We investigated whether a single auscultation training class using a cardiology patient simulator for medical students provides competence required for clinical clerkship, and whether students' proficiency after the training differs among heart sounds and murmurs. A total of 324 fourth-year medical students (93-117/year for 3 years) were divided into groups of 6-8 students; each group participated in a three-hour training session using a cardiology patient simulator. After a mini-lecture and facilitated training, each student took two different tests. In the first test, they tried to identify three sounds of Category A (non-split, respiratory split, and abnormally wide split S2s) in random order, after being informed that they were from Category A. They then did the same with sounds of Category B (S3, S4, and S3+S4) and Category C (four heart murmurs). In the second test, they tried to identify only one from each of the three categories in random order without any category information. The overall accuracy rate declined from 80.4% in the first test to 62.0% in the second test (p<0.0001). The accuracy rate of all the heart murmurs was similar in the first (81.3%) and second tests (77.5%). That of all the heart sounds (S2/S3/S4) decreased from 79.9% to 54.3% in the second test (p<0.0001). The individual accuracy rate decreased in the second test as compared with the first test in all three S2s, S3, and S3+S4 (p<0.0001). Medical students may be less likely to correctly identify S2/S3/S4 as compared with heart murmurs in a situation close to clinical setting even immediately after training. We may have to consider such a characteristic of students when we provide them with cardiac auscultation training. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  16. Spatial and Temporal Variability and Trends in 2001-2016 Global Fire Activity

    NASA Astrophysics Data System (ADS)

    Earl, Nick; Simmonds, Ian

    2018-03-01

    Fire regimes across the globe have great spatial and temporal variability, and these are influence by many factors including anthropogenic management, climate, and vegetation types. Here we utilize the satellite-based "active fire" product, from Moderate Resolution Imaging Spectroradiometer (MODIS) sensors, to statistically analyze variability and trends in fire activity from the global to regional scales. We split up the regions by economic development, region/geographical land use, clusters of fire-abundant areas, or by religious/cultural influence. Weekly cycle tests are conducted to highlight and quantify part of the anthropogenic influence on fire regime across the world. We find that there is a strong statistically significant decline in 2001-2016 active fires globally linked to an increase in net primary productivity observed in northern Africa, along with global agricultural expansion and intensification, which generally reduces fire activity. There are high levels of variability, however. The large-scale regions exhibit either little change or decreasing in fire activity except for strong increasing trends in India and China, where rapid population increase is occurring, leading to agricultural intensification and increased crop residue burning. Variability in Canada has been linked to a warming global climate leading to a longer growing season and higher fuel loads. Areas with a strong weekly cycle give a good indication of where fire management is being applied most extensively, for example, the United States, where few areas retain a natural fire regime.

  17. Clinical potential of a silk sericin-releasing bioactive wound dressing for the treatment of split-thickness skin graft donor sites.

    PubMed

    Siritientong, Tippawan; Angspatt, Apichai; Ratanavaraporn, Juthamas; Aramwit, Pornanong

    2014-01-01

    An ethyl alcohol-precipitated silk sericin/PVA scaffold that controlled the release of silk sericin was previously developed and applied for the treatment of full-thickness wounds in rats and demonstrated efficient healing. In this study, we aimed to further evaluate the clinical potential of this scaffold, hereafter called "silk sericin-releasing wound dressing", for the treatment of split-thickness skin graft donor sites by comparison with the clinically available wound dressing known as "Bactigras®". In vitro characterization and in vivo evaluation for safety of the wound dressings were performed. A clinical trial of the wound dressings was conducted according to standard protocols. The sericin released from the wound dressing was not toxic to HaCat human keratinocytes. A peel test indicated that the silk sericin-releasing wound dressing was less adhesive than Bactigras®, potentially reducing trauma and the risk of repeated injury upon removal. There was no evidence of skin irritation upon treatment with either wound dressing. When tested in patients with split-thickness skin graft donor sites, the wounds treated with the silk sericin-releasing wound dressing exhibited complete healing at 12 ± 5.0 days, whereas those treated with Bactigras® were completely healed at 14 ± 5.2 days (p = 1.99 × 10(-4)). In addition, treatment with the silk sericin-releasing wound dressing significantly reduced pain compared with Bactigras® particularly during the first 4 postoperative days (p = 2.70 × 10(-5) on day 1). We introduce this novel silk sericin-releasing wound dressing as an alternative treatment for split-thickness skin graft donor sites.

  18. Entropy Splitting for High Order Numerical Simulation of Compressible Turbulence

    NASA Technical Reports Server (NTRS)

    Sandham, N. D.; Yee, H. C.; Kwak, Dochan (Technical Monitor)

    2000-01-01

    A stable high order numerical scheme for direct numerical simulation (DNS) of shock-free compressible turbulence is presented. The method is applicable to general geometries. It contains no upwinding, artificial dissipation, or filtering. Instead the method relies on the stabilizing mechanisms of an appropriate conditioning of the governing equations and the use of compatible spatial difference operators for the interior points (interior scheme) as well as the boundary points (boundary scheme). An entropy splitting approach splits the inviscid flux derivatives into conservative and non-conservative portions. The spatial difference operators satisfy a summation by parts condition leading to a stable scheme (combined interior and boundary schemes) for the initial boundary value problem using a generalized energy estimate. A Laplacian formulation of the viscous and heat conduction terms on the right hand side of the Navier-Stokes equations is used to ensure that any tendency to odd-even decoupling associated with central schemes can be countered by the fluid viscosity. A special formulation of the continuity equation is used, based on similar arguments. The resulting methods are able to minimize spurious high frequency oscillation producing nonlinear instability associated with pure central schemes, especially for long time integration simulation such as DNS. For validation purposes, the methods are tested in a DNS of compressible turbulent plane channel flow at a friction Mach number of 0.1 where a very accurate turbulence data base exists. It is demonstrated that the methods are robust in terms of grid resolution, and in good agreement with incompressible channel data, as expected at this Mach number. Accurate turbulence statistics can be obtained with moderate grid sizes. Stability limits on the range of the splitting parameter are determined from numerical tests.

  19. Evaluation of concrete characteristics for rigid pavements.

    DOT National Transportation Integrated Search

    1998-04-01

    The researcher developed correlations among flexural, split tensile, and compressive strengths and ultrasonic pulse velocity from laboratory testing using materials and mix designs proposed for use in a paving project. These relationships were used t...

  20. Physical performance characteristics of high-level female soccer players 12-21 years of age.

    PubMed

    Vescovi, J D; Rupf, R; Brown, T D; Marques, M C

    2011-10-01

    Performance assessment has become an invaluable component of monitoring player development and within talent identification programs in soccer, yet limited performance data are available for female soccer players across a wide age range. The aim of this study was to describe the physical performance characteristics of female soccer players ranging in age from 12 to 21 years. High-level female soccer players (n=414) were evaluated on linear sprinting (36.6 m with 9.1 m splits), countermovement jump (CMJ), and two agility tests. Separate one-way ANOVAs were used to compare performance characteristics between (1) each year of chronological age and (2) three age groups: 12-13 years, n=78, 14-17 years, n=223, and 18-21 years, n=113. Mean linear sprint speed over 9.1 m was similar across all chronological ages, however sprint speed over the final 9.1 m, CMJ height and agility scores improved until approximately 15-16 years. Outcomes from the group data indicated better performance on all tests for the 14-17-year-old group compared with the 12-13-year-old group. Additionally, sprint speed on the second and fourth 9.1 m splits and 36.6 m sprint speed as well as performance on the Illinois agility test was better in the 18-21-year-old group compared with the 14-17-year-old group. The findings from this study indicate that marked improvements of high intensity short duration work occur up until 15-16 years. Smaller gains in performance were observed beyond 16 years of age as evidenced by better performance on 36.6 m sprint speed, several sprint splits and the Illinois agility test in the college aged players (i.e., 18-21-year-old group). © 2010 John Wiley & Sons A/S.

  1. World Trade Center human identification project: experiences with individual body identification cases.

    PubMed

    Budimlija, Zoran M; Prinz, Mechthild K; Zelson-Mundorff, Amy; Wiersema, Jason; Bartelink, Eric; MacKinnon, Gaille; Nazzaruolo, Bianca L; Estacio, Sheila M; Hennessey, Michael J; Shaler, Robert C

    2003-06-01

    To present individual body identification efforts, as part of the World Trade Center (WTC) mass disaster identification project. More than 500 samples were tested by using polymerase chain reaction (PCR) amplification and short tandem repeat (STR) typing. The extent to which the remains were fragmented and affected by taphonomic factors complicated the identification project. Anthropologists reviewed 19,000 samples, and detected inconsistencies in 69, which were further split into 239 new cases and re-sampled by DNA specialists. The severity and nature of the disaster required an interdisciplinary effort. DNA profiling of 500 samples was successful in 75% of the cases. All discrepancies, which occurred between bone and tissue samples taken from the same body part, were resolved by re-sampling and re-testing of preferably bone tissue. Anthropologists detected inconsistencies in 69 cases, which were then split into 239 new cases. Out of 125 "split" cases, 65 were excluded from their original case. Of these 65 cases, 37 did not match any profiles in M-FISys, probably because profiles were incomplete or no exemplar for the victim was available. Out of the 60 remains not excluded from their original case, 30 were partial profiles and did not reach the statistical requirement to match their original case, because the population frequency of the DNA profile had to be

  2. A cooperative-binding split aptamer assay for rapid, specific and ultra-sensitive fluorescence detection of cocaine in saliva† †Electronic supplementary information (ESI) available: Optimization of Mg2+ and ATMND concentrations for our CBSA-based ATMND-binding assay; ATMND-reported calibration curve for CBSA-5325 at various cocaine concentrations; ATMND binding affinity for the cocaine-assembled CBSA-5325; K D of 38-GC and different 38-GC mutants for cocaine as characterized by ITC; stem length effects on cocaine-induced CBSA assembly; spectra of CBSA-5335-based fluorescence detection of cocaine in 1× binding buffer; characterization of cocaine binding affinity of CBSA-5335 and PSA using ITC; fluorescence detection of cocaine in saliva with our fluorophore/quencher modified CBSA-5335; calibration curve of our CBSA-5335-based fluorophore/quencher assay in 1× binding buffer and 10% saliva at cocaine concentrations ranging from 0 to 10 μM; bias and precision of the CBSA-5335-based fluorophore/quencher assay; comparison of amplification-free split-aptamer assays for cocaine detection; sequence ID and DNA sequences used in this work. See DOI: 10.1039/c6sc01833e Click here for additional data file.

    PubMed Central

    Yu, Haixiang; Canoura, Juan; Guntupalli, Bhargav; Lou, Xinhui

    2017-01-01

    Sensors employing split aptamers that reassemble in the presence of a target can achieve excellent specificity, but the accompanying reduction of target affinity mitigates any overall gains in sensitivity. We for the first time have developed a split aptamer that achieves enhanced target-binding affinity through cooperative binding. We have generated a split cocaine-binding aptamer that incorporates two binding domains, such that target binding at one domain greatly increases the affinity of the second domain. We experimentally demonstrate that the resulting cooperative-binding split aptamer (CBSA) exhibits higher target binding affinity and is far more responsive in terms of target-induced aptamer assembly compared to the single-domain parent split aptamer (PSA) from which it was derived. We further confirm that the target-binding affinity of our CBSA can be affected by the cooperativity of its binding domains and the intrinsic affinity of its PSA. To the best of our knowledge, CBSA-5335 has the highest cocaine affinity of any split aptamer described to date. The CBSA-based assay also demonstrates excellent performance in target detection in complex samples. Using this CBSA, we achieved specific, ultra-sensitive, one-step fluorescence detection of cocaine within fifteen minutes at concentrations as low as 50 nM in 10% saliva without signal amplification. This limit of detection meets the standards recommended by the European Union's Driving under the Influence of Drugs, Alcohol and Medicines program. Our assay also demonstrates excellent reproducibility of results, confirming that this CBSA-platform represents a robust and sensitive means for cocaine detection in actual clinical samples. PMID:28451157

  3. On Lack of Robustness in Hydrological Model Development Due to Absence of Guidelines for Selecting Calibration and Evaluation Data: Demonstration for Data-Driven Models

    NASA Astrophysics Data System (ADS)

    Zheng, Feifei; Maier, Holger R.; Wu, Wenyan; Dandy, Graeme C.; Gupta, Hoshin V.; Zhang, Tuqiao

    2018-02-01

    Hydrological models are used for a wide variety of engineering purposes, including streamflow forecasting and flood-risk estimation. To develop such models, it is common to allocate the available data to calibration and evaluation data subsets. Surprisingly, the issue of how this allocation can affect model evaluation performance has been largely ignored in the research literature. This paper discusses the evaluation performance bias that can arise from how available data are allocated to calibration and evaluation subsets. As a first step to assessing this issue in a statistically rigorous fashion, we present a comprehensive investigation of the influence of data allocation on the development of data-driven artificial neural network (ANN) models of streamflow. Four well-known formal data splitting methods are applied to 754 catchments from Australia and the U.S. to develop 902,483 ANN models. Results clearly show that the choice of the method used for data allocation has a significant impact on model performance, particularly for runoff data that are more highly skewed, highlighting the importance of considering the impact of data splitting when developing hydrological models. The statistical behavior of the data splitting methods investigated is discussed and guidance is offered on the selection of the most appropriate data splitting methods to achieve representative evaluation performance for streamflow data with different statistical properties. Although our results are obtained for data-driven models, they highlight the fact that this issue is likely to have a significant impact on all types of hydrological models, especially conceptual rainfall-runoff models.

  4. Splitting the mind within the individual, nation and economy: reflections on the struggle for integration in post-war Germany.

    PubMed

    Plänkers, Tomas

    2015-02-01

    With respect to theorisations of psychical splitting, this paper explores the psychical mechanisms that underlie different forms of social splitting. The paper first outlines Freud's and Kleins different theorisations of the psychical mechanisms of splitting, where the good is split from the bad, the inside split from the outside, and the painful disavowed. I then consider the psychical mechanisms of splitting that underlie ideological supports of certain social systems, specifically that of National Socialist Germany, East Germany during the Cold War period, and neoliberal capitalism. Here, I consider ideological splits between good and evil, the relation between external and internal splits, the relation between geographical, social and internal splitting, as well as splitting as disavowal of the other. Copyright © 2015 Institute of Psychoanalysis.

  5. Coronal and Intraradicular Appearances Affect Radiographic Perception of the Periapical Region.

    PubMed

    Strong, Julie W; Woodmansey, Karl F; Khademi, John A; Hatton, John F

    2017-05-01

    The influence of the radiographic appearances of the coronal and intraradicular areas on periapical radiographic interpretation has been minimally evaluated in dentistry and endodontics. The purpose of this study was to evaluate the effects that the coronal and intraradicular radiographic appearance has on endodontists' radiographic interpretations of periapical areas. In a split-group study design using an online survey format, 2 pairs of digital periapical radiographic images were evaluated by 2 groups (A and B) of endodontist readers for the presence of a periapical finding. The images in each pair were identical except that 1 image of each image pairs had coronal restorations and/or root canal fillings altered using Adobe Photoshop software (Adobe Systems, San Jose, CA). The periapical areas were not altered. Using a 5-point Likert scale, the endodontist readers were asked to "Please evaluate the periapical area(s)." A Mann-Whitney U test was used to statistically evaluate the difference between the groups. Significance was set at P < .01. There were 417 readers in group A and 442 readers in group B. The Mann-Whitney U test showed a significant difference in the responses between the groups for both image pairs (P < .01). Because the periapical areas of the image pairs were unaltered, the differing coronal and intraradicular areas of the radiographs appear to have influenced endodontists' interpretations of the periapical areas. This finding has implications for all radiographic outcome assessments. Copyright © 2017 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  6. "Split Them!" Smaller Item Sizes of Cookies Lead to a Decrease in Energy Intake in Children

    ERIC Educational Resources Information Center

    Marchiori, David; Waroquier, Laurent; Klein, Olivier

    2012-01-01

    Objective: Examine the influence of altering the size of snack food (ie, small vs large cookies) on short-term energy intake. Methods: First- and sixth-graders (n = 77) participated in a between-subjects experimental design. All participants were offered the same gram weight of cookies during an afternoon tea at their school. For half of the…

  7. Effects of atmospheric CO[sub 2] and soil NO[sub 3][sup [minus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lindroth, R.L.; Kinney, K.K.

    1993-06-01

    Physiological and growth responses of trees to elevated atmospheric CO[sub 2] are influenced by soil nutrient availability. Interactive effects of these factors on tree chemical composition, however, are largely unknown. We used a split-plot experimental design to assess the impact of CO[sub 2] (whole plots; 355 and 650 ppm) and soil NO[sub 3][sup [minus

  8. Experimental Validation of the Half-Length Force Concept Inventory

    ERIC Educational Resources Information Center

    Han, Jing; Koenig, Kathleen; Cui, Lili; Fritchman, Joseph; Li, Dan; Sun, Wanyi; Fu, Zhao; Bao, Lei

    2016-01-01

    In a recent study, the 30-question Force Concept Inventory (FCI) was theoretically split into two 14-question "half-length" tests (HFCIs) covering the same set of concepts and producing mean scores that can be equated to those of the original FCI. The HFCIs require less administration time and reduce test-retest issues when different…

  9. ENVIRONMENTAL TEHNOLOGY VERIFICATION REPORT - PHYSICAL REMOVAL OF MICROBIAL CONTAMINATION AGENTS IN DRINKING WATER, KINETICO INCORPORATED PALL/KINETICO PUREFECTA™ DRINKING WATER TREATMENT SYSTEM (POU)

    EPA Science Inventory

    The Purefecta™ was tested for removal of bacteria and viruses at NSF International's Drinking Water Treatment Systems Laboratory. Kinetico submitted 10 units for testing, which were split into two groups of five. One group received 25 days of conditioning prior to challeng...

  10. Upper Mantle Responses to India-Eurasia Collision in Indochina, Malaysia, and the South China Sea

    NASA Astrophysics Data System (ADS)

    Hongsresawat, S.; Russo, R. M.

    2016-12-01

    We present new shear wave splitting and splitting intensity measurements from SK(K)S phases recorded at seismic stations of the Malaysian National Seismic Network. These results, in conjunction with results from Tibet and Yunnan provide a basis for testing the degree to which Indochina and South China Sea upper mantle fabrics are responses to India-Eurasia collision. Upper mantle fabrics derived from shear wave splitting measurements in Yunnan and eastern Tibet parallel geodetic surface motions north of 26°N, requiring transmission of tractions from upper mantle depths to surface, or consistent deformation boundary conditions throughout the upper 200 km of crust and mantle. Shear wave splitting fast trends and surface velocities diverge in eastern Yunnan and south of 26°N, indicating development of an asthenospheric layer that decouples crust and upper mantle, or corner flow above the subducted Indo-Burma slab. E-W fast shear wave splitting trends southwest of 26°N/104°E indicate strong gradients in any asthenospheric infiltration. Possible upper mantle flow regimes beneath Indochina include development of olivine b-axis anisotropic symmetry due to high strain and hydrous conditions in the syntaxis/Indo-Burma mantle wedge (i.e., southward flow), development of strong upper mantle corner flow in the Indo-Burma wedge with olivine a-axis anisotropic symmetry (i.e., westward flow), and simple asthenospheric flow due to eastward motion of Sundaland shearing underlying asthenosphere. Further south, shear-wave splitting delay times at Malaysian stations vary from 0.5 seconds on the Malay Peninsula to over 2 seconds at stations on Borneo. Splitting fast trends at Borneo stations and Singapore trend NE-SW, but in northern Peninsular Malaysia, the splitting fast polarization direction is NW-SE, parallel to the trend of the Peninsula. Thus, there is a sharp transition from low delay time and NW-SE fast polarization to high delay times and fast polarization directions that parallel the strike of the now-inoperative spreading center in the South China Sea. This transition appears to occur in the central portion of Peninsular Malaysia and may mark the boundary between Tethyan upper mantle extruded from the India-Asia collision zone and supra-subduction upper mantle of the Indonesian arc.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Simbeck, D.J.

    Toxicity testing of split whole sediment samples using juvenile freshwater mussels (Anodonta imbecillis) was conducted by TVA to provide a quality assurance mechanism for test organism quality and overall performance of the test being conducted by CR-ERP personnel as part of the CR-ERP biomonitoring study of Clinch River sediments. Testing of sediment samples collected September 8 from Poplar Creek Miles 6.0 and 1.0 was conducted September 13-22, 1994. Results from this test showed no toxicity (survival effects) to fresh-water mussels during a 9-day exposure to the sediments.

  12. Dual-Energy Computed Tomography Angiography of the Head and Neck With Single-Source Computed Tomography: A New Technical (Split Filter) Approach for Bone Removal.

    PubMed

    Kaemmerer, Nadine; Brand, Michael; Hammon, Matthias; May, Matthias; Wuest, Wolfgang; Krauss, Bernhard; Uder, Michael; Lell, Michael M

    2016-10-01

    Dual-energy computed tomographic angiography (DE-CTA) has been demonstrated to improve the visualization of the head and neck vessels. The aim of this study was to test the potential of split-filter single-source dual-energy CT to automatically remove bone from the final CTA data set. Dual-energy CTA was performed in 50 consecutive patients to evaluate the supra-aortic arteries, either to grade carotid artery stenosis or to rule out traumatic dissections. Dual-energy CTA was performed on a 128-slice single-source CT system equipped with a special filter array to separate the 120-kV spectrum into a high- and a low-energy spectrum for DE-based automated bone removal. Image quality of fully automated bone suppression and subsequent manual optimization was evaluated by 2 radiologists on maximum intensity projections using a 4-grade scoring system. The effect of image reconstruction with an iterative metal artifact reduction algorithm on DE postprocessing was tested using a 3-grade scoring system, and the time demand for each postprocessing step was measured. Two patients were excluded due to insufficient arterial contrast enhancement; in the remaining 48 patients, automated bone removal could be performed successfully. The addition of iterative metal artifact reduction algorithm improved image quality in 58.3% of the cases. After manual optimization, DE-CTA image quality was rated excellent in 7, good in 29, and moderate in 10 patients. Interobserver agreement was high (κ = 0.85). Stenosis grading was not influenced using DE-CTA with bone removal as compared with the original CTA. The time demand for DE image reconstruction was significantly higher than for single-energy reconstruction (42.1 vs 20.9 seconds). Our results suggest that bone removal in DE-CTA of the head and neck vessels with a single-source CT is feasible and can be performed within acceptable time and moderate user interaction.

  13. Genome expansion via lineage splitting and genome reduction in the cicada endosymbiont Hodgkinia.

    PubMed

    Campbell, Matthew A; Van Leuven, James T; Meister, Russell C; Carey, Kaitlin M; Simon, Chris; McCutcheon, John P

    2015-08-18

    Comparative genomics from mitochondria, plastids, and mutualistic endosymbiotic bacteria has shown that the stable establishment of a bacterium in a host cell results in genome reduction. Although many highly reduced genomes from endosymbiotic bacteria are stable in gene content and genome structure, organelle genomes are sometimes characterized by dramatic structural diversity. Previous results from Candidatus Hodgkinia cicadicola, an endosymbiont of cicadas, revealed that some lineages of this bacterium had split into two new cytologically distinct yet genetically interdependent species. It was hypothesized that the long life cycle of cicadas in part enabled this unusual lineage-splitting event. Here we test this hypothesis by investigating the structure of the Ca. Hodgkinia genome in one of the longest-lived cicadas, Magicicada tredecim. We show that the Ca. Hodgkinia genome from M. tredecim has fragmented into multiple new chromosomes or genomes, with at least some remaining partitioned into discrete cells. We also show that this lineage-splitting process has resulted in a complex of Ca. Hodgkinia genomes that are 1.1-Mb pairs in length when considered together, an almost 10-fold increase in size from the hypothetical single-genome ancestor. These results parallel some examples of genome fragmentation and expansion in organelles, although the mechanisms that give rise to these extreme genome instabilities are likely different.

  14. The effect of split pixel HDR image sensor technology on MTF measurements

    NASA Astrophysics Data System (ADS)

    Deegan, Brian M.

    2014-03-01

    Split-pixel HDR sensor technology is particularly advantageous in automotive applications, because the images are captured simultaneously rather than sequentially, thereby reducing motion blur. However, split pixel technology introduces artifacts in MTF measurement. To achieve a HDR image, raw images are captured from both large and small sub-pixels, and combined to make the HDR output. In some cases, a large sub-pixel is used for long exposure captures, and a small sub-pixel for short exposures, to extend the dynamic range. The relative size of the photosensitive area of the pixel (fill factor) plays a very significant role in the output MTF measurement. Given an identical scene, the MTF will be significantly different, depending on whether you use the large or small sub-pixels i.e. a smaller fill factor (e.g. in the short exposure sub-pixel) will result in higher MTF scores, but significantly greater aliasing. Simulations of split-pixel sensors revealed that, when raw images from both sub-pixels are combined, there is a significant difference in rising edge (i.e. black-to-white transition) and falling edge (white-to-black) reproduction. Experimental results showed a difference of ~50% in measured MTF50 between the falling and rising edges of a slanted edge test chart.

  15. Model validations for low-global warming potential refrigerants in mini-split air-conditioning units

    DOE PAGES

    Shen, Bo; Shrestha, Som; Abdelaziz, Omar

    2016-09-02

    To identify low GWP (global warming potential) refrigerants to replace R-22 and R-410A, extensive experimental evaluations were conducted for multiple candidates of refrigerant at the standard test conditions and at high-ambient conditions with outdoor temperature varying from 27.8 C to 55.0 C.. In the study, R-22 was compared to propane (R-290), DR-3, ARM-20B, N-20B and R-444B in a mini-split air conditioning unit originally designed for R-22; R-410A was compared to R-32, DR-55, ARM-71A, L41-2 (R-447A) in a mini-split unit designed for R-410A. To reveal physics behind the measured performance results, thermodynamic properties of the alternative refrigerants were analysed. In addition,more » the experimental data was used to calibrate a physics-based equipment model, i.e. ORNL Heat Pump Design Model (HPDM). The calibrated model translated the experimental results to key calculated parameters, i.e. compressor efficiencies, refrigerant side two-phase heat transfer coefficients, corresponding to each refrigerant. As a result, these calculated values provide scientific insights on the performance of the alternative refrigerants and are useful for other applications beyond mini-split air conditioning units.« less

  16. Spin-orbit coupling calculations with the two-component normalized elimination of the small component method

    NASA Astrophysics Data System (ADS)

    Filatov, Michael; Zou, Wenli; Cremer, Dieter

    2013-07-01

    A new algorithm for the two-component Normalized Elimination of the Small Component (2cNESC) method is presented and tested in the calculation of spin-orbit (SO) splittings for a series of heavy atoms and their molecules. The 2cNESC is a Dirac-exact method that employs the exact two-component one-electron Hamiltonian and thus leads to exact Dirac SO splittings for one-electron atoms. For many-electron atoms and molecules, the effect of the two-electron SO interaction is modeled by a screened nucleus potential using effective nuclear charges as proposed by Boettger [Phys. Rev. B 62, 7809 (2000), 10.1103/PhysRevB.62.7809]. The use of the screened nucleus potential for the two-electron SO interaction leads to accurate spinor energy splittings, for which the deviations from the accurate Dirac Fock-Coulomb values are on the average far below the deviations observed for other effective one-electron SO operators. For hydrogen halides HX (X = F, Cl, Br, I, At, and Uus) and mercury dihalides HgX2 (X = F, Cl, Br, I) trends in spinor energies and SO splittings as obtained with the 2cNESC method are analyzed and discussed on the basis of coupling schemes and the electronegativity of X.

  17. MIP Models and Hybrid Algorithms for Simultaneous Job Splitting and Scheduling on Unrelated Parallel Machines

    PubMed Central

    Ozmutlu, H. Cenk

    2014-01-01

    We developed mixed integer programming (MIP) models and hybrid genetic-local search algorithms for the scheduling problem of unrelated parallel machines with job sequence and machine-dependent setup times and with job splitting property. The first contribution of this paper is to introduce novel algorithms which make splitting and scheduling simultaneously with variable number of subjobs. We proposed simple chromosome structure which is constituted by random key numbers in hybrid genetic-local search algorithm (GAspLA). Random key numbers are used frequently in genetic algorithms, but it creates additional difficulty when hybrid factors in local search are implemented. We developed algorithms that satisfy the adaptation of results of local search into the genetic algorithms with minimum relocation operation of genes' random key numbers. This is the second contribution of the paper. The third contribution of this paper is three developed new MIP models which are making splitting and scheduling simultaneously. The fourth contribution of this paper is implementation of the GAspLAMIP. This implementation let us verify the optimality of GAspLA for the studied combinations. The proposed methods are tested on a set of problems taken from the literature and the results validate the effectiveness of the proposed algorithms. PMID:24977204

  18. Model validations for low-global warming potential refrigerants in mini-split air-conditioning units

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shen, Bo; Shrestha, Som; Abdelaziz, Omar

    To identify low GWP (global warming potential) refrigerants to replace R-22 and R-410A, extensive experimental evaluations were conducted for multiple candidates of refrigerant at the standard test conditions and at high-ambient conditions with outdoor temperature varying from 27.8 C to 55.0 C.. In the study, R-22 was compared to propane (R-290), DR-3, ARM-20B, N-20B and R-444B in a mini-split air conditioning unit originally designed for R-22; R-410A was compared to R-32, DR-55, ARM-71A, L41-2 (R-447A) in a mini-split unit designed for R-410A. To reveal physics behind the measured performance results, thermodynamic properties of the alternative refrigerants were analysed. In addition,more » the experimental data was used to calibrate a physics-based equipment model, i.e. ORNL Heat Pump Design Model (HPDM). The calibrated model translated the experimental results to key calculated parameters, i.e. compressor efficiencies, refrigerant side two-phase heat transfer coefficients, corresponding to each refrigerant. As a result, these calculated values provide scientific insights on the performance of the alternative refrigerants and are useful for other applications beyond mini-split air conditioning units.« less

  19. Asymmetric adiabatic couplers for fully-integrated broadband quantum-polarization state preparation.

    PubMed

    Chung, Hung-Pin; Huang, Kuang-Hsu; Wang, Kai; Yang, Sung-Lin; Yang, Shih-Yuan; Sung, Chun-I; Solntsev, Alexander S; Sukhorukov, Andrey A; Neshev, Dragomir N; Chen, Yen-Hung

    2017-12-04

    Spontaneous parametric down-conversion (SPDC) is a widely used method to generate entangled photons, enabling a range of applications from secure communication to tests of quantum physics. Integrating SPDC on a chip provides interferometric stability, allows to reduce a physical footprint, and opens a pathway to true scalability. However, dealing with different photon polarizations and wavelengths on a chip presents a number of challenging problems. In this work, we demonstrate an on-chip polarization beam-splitter based on z-cut titanium-diffused lithium niobate asymmetric adiabatic couplers (AAC) designed for integration with a type-II SPDC source. Our experimental measurements reveal unique polarization beam-splitting regime with the ability to tune the splitting ratios based on wavelength. In particular, we measured a splitting ratio of 17 dB over broadband regions (>60 nm) for both H- and V-polarized lights and a specific 50%/50% splitting ratio for a cross-polarized photon pair from the AAC. The results show that such a system can be used for preparing different quantum polarization-path states that are controllable by changing the phase-matching conditions in the SPDC over a broad band. Furthermore, we propose a fully integrated electro-optically tunable type-II SPDC polarization-path-entangled state preparation circuit on a single lithium niobate photonic chip.

  20. Appendix E : FIB-63 tests.

    DOT National Transportation Integrated Search

    2013-03-01

    Web splitting cracks (Figure 1) typically form during prestress transfer, or in the days and : weeks following transfer. They occur due to tensile stresses that are induced as prestressing : forces in the bottom flange are distributed through the cro...

  1. Lateralization for Processing Facial Emotions in Gay Men, Heterosexual Men, and Heterosexual Women.

    PubMed

    Rahman, Qazi; Yusuf, Sifat

    2015-07-01

    This study tested whether male sexual orientation and gender nonconformity influenced functional cerebral lateralization for the processing of facial emotions. We also tested for the effects of sex of poser and emotion displayed on putative differences. Thirty heterosexual men, 30 heterosexual women, and 40 gay men completed measures of demographic variables, recalled childhood gender nonconformity (CGN), IQ, and the Chimeric Faces Test (CFT). The CFT depicts vertically split chimeric faces, formed with one half showing a neutral expression and the other half showing an emotional expression and performance is measured using a "laterality quotient" (LQ) score. We found that heterosexual men were significantly more right-lateralized when viewing female faces compared to heterosexual women and gay men, who did not differ significantly from each other. Heterosexual women and gay men were more left-lateralized for processing female faces. There were no significant group differences in lateralization for male faces. These results remained when controlling for age and IQ scores. There was no significant effect of CGN on LQ scores. These data suggest that gay men are feminized in some aspects of functional cerebral lateralization for facial emotion. The results were discussed in relation to the selectivity of functional lateralization and putative brain mechanisms underlying sexual attraction towards opposite-sex and same-sex targets.

  2. Split-brain phenomena in anterior communicating artery aneurysm rupture: A case report.

    PubMed

    Korsakova, Natalya; Liebson, Elizabeth; Moskovich, Lena

    2017-06-01

    In 1976, a patient with an anterior communicating artery aneurysm (ACoAA) rupture (diagnosed on angiography) and sub-arachnoid hemorrhage (SAH) underwent serial neuropsychological testing revealing a classical anterior cerebral artery (ACA) spasm picture with severe anterograde amnesia of Korsakoff's type and dysexecutive syndrome. In addition, the patient demonstrated impaired hemispheric interaction with alien hand syndrome, dyscopia-dysgraphia, complete left ear neglect, and other, more complex, split-brain phenomena. He was evaluated by A. R. Luria in 1976. Following surgery the patient demonstrated gradual improvement. © 2017 The Institute of Psychology, Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.

  3. Numerical methods for systems of conservation laws of mixed type using flux splitting

    NASA Technical Reports Server (NTRS)

    Shu, Chi-Wang

    1990-01-01

    The essentially non-oscillatory (ENO) finite difference scheme is applied to systems of conservation laws of mixed hyperbolic-elliptic type. A flux splitting, with the corresponding Jacobi matrices having real and positive/negative eigenvalues, is used. The hyperbolic ENO operator is applied separately. The scheme is numerically tested on the van der Waals equation in fluid dynamics. Convergence was observed with good resolution to weak solutions for various Riemann problems, which are then numerically checked to be admissible as the viscosity-capillarity limits. The interesting phenomena of the shrinking of elliptic regions if they are present in the initial conditions were also observed.

  4. StackSplit - a plugin for multi-event shear wave splitting analyses in SplitLab

    NASA Astrophysics Data System (ADS)

    Grund, Michael

    2017-04-01

    The SplitLab package (Wüstefeld et al., Computers and Geosciences, 2008), written in MATLAB, is a powerful and widely used tool for analysing seismological shear wave splitting of single event measurements. However, in many cases, especially temporary station deployments close to seaside or for recordings affected by strong anthropogenic noise, only multi-event approaches provide stable and reliable splitting results. In order to extend the original SplitLab environment for such analyses, I present the StackSplit plugin that can easily be implemented within the well accepted main program. StackSplit grants easy access to several different analysis approaches within SplitLab, including a new multiple waveform based inversion method as well as the most established standard stacking procedures. The possibility to switch between different analysis approaches at any time allows the user for the most flexible processing of individual multi-event splitting measurements for a single recording station. Besides the provided functions of the plugin, no other external program is needed for the multi-event analyses since StackSplit performs within the available SplitLab structure.

  5. Splitting of IVP bovine blastocyst affects morphology and gene expression of resulting demi-embryos during in vitro culture and in vivo elongation.

    PubMed

    Velasquez, Alejandra E; Castro, Fidel O; Veraguas, Daniel; Cox, Jose F; Lara, Evelyn; Briones, Mario; Rodriguez-Alvarez, Lleretny

    2016-02-01

    Embryo splitting might be used to increase offspring yield and for molecular analysis of embryo competence. How splitting affects developmental potential of embryos is unknown. This research aimed to study the effect of bovine blastocyst splitting on morphological and gene expression homogeneity of demi-embryos and on embryo competence during elongation. Grade I bovine blastocyst produced in vitro were split into halves and distributed in nine groups (3 × 3 setting according to age and stage before splitting; age: days 7-9; stage: early, expanded and hatched blastocysts). Homogeneity and survival rate in vitro after splitting (12 h, days 10 and 13) and the effect of splitting on embryo development at elongation after embryo transfer (day 17) were assessed morphologically and by RT-qPCR. The genes analysed were OCT4, SOX2, NANOG, CDX2, TP1, TKDP1, EOMES, and BAX. Approximately 90% of split embryos had a well conserved defined inner cell mass (ICM), 70% of the halves had similar size with no differences in gene expression 12 h after splitting. Split embryos cultured further conserved normal and comparable morphology at day 10 of development; this situation changes at day 13 when embryo morphology and gene expression differed markedly among demi-embryos. Split and non-split blastocysts were transferred to recipient cows and were recovered at day 17. Fifty per cent of non-split embryos were larger than 100 mm (33% for split embryos). OCT4, SOX2, TP1 and EOMES levels were down-regulated in elongated embryos derived from split blastocysts. In conclusion, splitting day-8 blastocysts yields homogenous demi-embryos in terms of developmental capability and gene expression, but the initiation of the filamentous stage seems to be affected by the splitting.

  6. Strain Rate Behavior of HTPB-Based Magnetorheological Materials

    NASA Astrophysics Data System (ADS)

    Stoltz, Chad; Seminuk, Kenneth; Joshi, Vasant

    2013-06-01

    It is of particular interest to determine whether the mechanical properties of binder systems can be manipulated by adding ferrous or Magnetostrictive particulates. Strain rate response of two HTPB/Fe (Hydroxyl-terminated Polybutadiene/Iron) compositions under electromagnetic fields has been investigated using a Split Hopkinson Pressure bar arrangement equipped with aluminum bars. Two HTPB/Fe compositions were developed, the first without plasticizer and the second containing plasticizer. Samples were tested with and without the application of a 0.01 Tesla magnetic field coil. Strain gauge data taken from the Split Hopkinson Pressure bar has been used to determine what mechanical properties were changed by inducing a mild electromagnetic field onto each sample. The data reduction method to obtain stress-strain plots included dispersion corrections for deciphering minute changes due to compositional alterations. Data collected from the Split Hopkinson Pressure bar indicate changes in the Mechanical Stress-Strain curves and suggest that the impedance of a binder system can be altered by means of a magnetic field. We acknowledge the Defense Threat Reduction Agency for funding.

  7. Operator splitting method for simulation of dynamic flows in natural gas pipeline networks

    DOE PAGES

    Dyachenko, Sergey A.; Zlotnik, Anatoly; Korotkevich, Alexander O.; ...

    2017-09-19

    Here, we develop an operator splitting method to simulate flows of isothermal compressible natural gas over transmission pipelines. The method solves a system of nonlinear hyperbolic partial differential equations (PDEs) of hydrodynamic type for mass flow and pressure on a metric graph, where turbulent losses of momentum are modeled by phenomenological Darcy-Weisbach friction. Mass flow balance is maintained through the boundary conditions at the network nodes, where natural gas is injected or withdrawn from the system. Gas flow through the network is controlled by compressors boosting pressure at the inlet of the adjoint pipe. Our operator splitting numerical scheme ismore » unconditionally stable and it is second order accurate in space and time. The scheme is explicit, and it is formulated to work with general networks with loops. We test the scheme over range of regimes and network configurations, also comparing its performance with performance of two other state of the art implicit schemes.« less

  8. Energy-based operator splitting approach for the time discretization of coupled systems of partial and ordinary differential equations for fluid flows: The Stokes case

    NASA Astrophysics Data System (ADS)

    Carichino, Lucia; Guidoboni, Giovanna; Szopos, Marcela

    2018-07-01

    The goal of this work is to develop a novel splitting approach for the numerical solution of multiscale problems involving the coupling between Stokes equations and ODE systems, as often encountered in blood flow modeling applications. The proposed algorithm is based on a semi-discretization in time based on operator splitting, whose design is guided by the rationale of ensuring that the physical energy balance is maintained at the discrete level. As a result, unconditional stability with respect to the time step choice is ensured by the implicit treatment of interface conditions within the Stokes substeps, whereas the coupling between Stokes and ODE substeps is enforced via appropriate initial conditions for each substep. Notably, unconditional stability is attained without the need of subiterating between Stokes and ODE substeps. Stability and convergence properties of the proposed algorithm are tested on three specific examples for which analytical solutions are derived.

  9. A high temperature hybrid photovoltaic-thermal receiver employing spectral beam splitting for linear solar concentrators

    NASA Astrophysics Data System (ADS)

    Mojiri, Ahmad; Stanley, Cameron; Rosengarten, Gary

    2015-09-01

    Hybrid photovoltaic/thermal (PV-T) solar collectors are capable of delivering heat and electricity concurrently. Implementing such receivers in linear concentrators for high temperature applications need special considerations such as thermal decoupling of the photovoltaic (pv) cells from the thermal receiver. Spectral beam splitting of concentrated light provides an option for achieving this purpose. In this paper we introduce a relatively simple hybrid receiver configuration that spectrally splits the light between a high temperature thermal fluid and silicon pv cells using volumetric light filtering by semi-conductor doped glass and propylene glycol. We analysed the optical performance of this device theoretically using ray tracing and experimentally through the construction and testing of a full scale prototype. The receiver was mounted on a commercial parabolic trough concentrator in an outdoor experiment. The prototype receiver delivered heat and electricity at total thermal efficiency of 44% and electrical efficiency of 3.9% measured relative to the total beam energy incident on the primary mirror.

  10. Fracturing And Liquid CONvection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2012-02-29

    FALCON has been developed to enable simulation of the tightly coupled fluid-rock behavior in hydrothermal and engineered geothermal system (EGS) reservoirs, targeting the dynamics of fracture stimulation, fluid flow, rock deformation, and heat transport in a single integrated code, with the ultimate goal of providing a tool that can be used to test the viability of EGS in the United States and worldwide. Reliable reservoir performance predictions of EGS systems require accurate and robust modeling for the coupled thermal-hydrological-mechanical processes. Conventionally, these types of problems are solved using operator-splitting methods, usually by coupling a subsurface flow and heat transport simulatormore » with a solid mechanics simulator via input files. FALCON eliminates the need for using operator-splitting methods to simulate these systems, and the scalability of the underlying MOOSE architecture allows for simulating these tightly coupled processes at the reservoir scale, allowing for examination of the system as a whole (something the operator-splitting methodologies generally cannot do).« less

  11. Application of photon Doppler velocimetry to direct impact Hopkinson pressure bars

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lea, Lewis J., E-mail: ll379@cam.ac.uk; Jardine, Andrew P.

    2016-02-15

    Direct impact Hopkinson pressure bar systems offer many potential advantages over split Hopkinson pressure bars, including access to higher strain rates, higher strains for equivalent striker velocity and system length, lower dispersion, and faster achievement of force equilibrium. Currently, these advantages are gained at the expense of all information about the striker impacted specimen face, preventing the experimental determination of force equilibrium, and requiring approximations to be made on the sample deformation history. In this paper, we discuss an experimental method and complementary data analysis for using photon Doppler velocimetry to measure surface velocities of the striker and output barsmore » in a direct impact bar experiment, allowing similar data to be recorded as in a split bar system. We discuss extracting velocity and force measurements, and the precision of measurements. Results obtained using the technique are compared to equivalent split bar tests, showing improved stress measurements for the lowest and highest strains in fully dense metals, and improvement for all strains in slow and non-equilibrating materials.« less

  12. Split-mode ultrasonic transducer.

    PubMed

    Ostrovskii, Igor; Cremaldi, Lucien

    2013-08-01

    A split-mode ultrasonic transducer is investigated in both theory and experiment. This transducer is a two-dimensional structure of periodically poled domains in a ferroelectric wafer with free surfaces. The acoustic vibrations are excited by a radio frequency electric current applied along the length of the wafer, which allows the basal-plane surfaces to be free of metal coatings and thus ready for further biomedical applications. A specific physical property of this transducer consists of the multiple acousto-electric resonances, which occur due to an acoustic mode split when the acoustic half-wavelength is equal to the domain length. Possible applications include ultrasonic generation and detection at the micro-scale, intravascular sonification and visualization, ultrasound therapy of localized small areas such as the eye, biomedical applications for cell cultures, and traditional nondestructive testing including bones and tissues. A potential use of a non-metallized wafer is a therapeutic application with double action that is both ultrasound itself and an electric field over the wafer. The experimental measurements and theoretical calculations are in good agreement.

  13. Electrodeposition of Ni-Mo alloy coatings for water splitting reaction

    NASA Astrophysics Data System (ADS)

    Shetty, Akshatha R.; Hegde, Ampar Chitharanjan

    2018-04-01

    The present study reports the development of Ni-Mo alloy coatings for water splitting applications, using a citrate bath the inducing effect of Mo (reluctant metal) on electrodeposition, its relationship with their electrocatalytic efficiency were studied. The alkaline water splitting efficiency of Ni-Mo alloy coatings, for both hydrogen evolution reaction (HER) and oxygen evolution reaction were tested using cyclic voltammetry (CV) and chronopotentiometry (CP) techniques. Moreover, the practical utility of these electrode materials were evaluated by measuring the amount of H2 and O2 gas evolved. The variation in electrocatalytic activity with composition, structure, and morphology of the coatings were examined using XRD, SEM, and EDS analyses. The experimental results showed that Ni-Mo alloy coating is the best electrode material for alkaline HER and OER reactions, at lower and higher deposition current densities (c. d.'s) respectively. This behavior is attributed by decreased Mo and increased Ni content of the alloy coating and the number of electroactive centers.

  14. Podokinetic Stimulation Causes Shifts in Perception of Straight Ahead

    PubMed Central

    Scott, John T.; Lohnes, Corey A.; Horak, Fay B.; Earhart, Gammon M.

    2011-01-01

    Podokinetic after-rotation (PKAR) is a phenomenon in which subjects inadvertently rotate when instructed to step in place after a period of walking on a rotating treadmill. PKAR has been shown to transfer between different forms of locomotion, but has not been tested in a non-locomotor task. We conducted two experiments to assess effects of PKAR on perception of subjective straight ahead and on quiet standing posture. Twenty-one healthy young right-handed subjects pointed to what they perceived as their subjective straight ahead with a laser pointer while they were recorded by a motion capture system both before and after a training period on the rotating treadmill. Subjects performed the pointing task while standing, sitting on a chair without a back, and a chair with a back. After the training period, subjects demonstrated a significant shift in subjective straight ahead, pointing an average of 29.1 ± 10.6 degrees off of center. The effect was direction-specific, depending on whether subjects had trained in the clockwise or counter-clockwise direction. Postures that limited subjects’ ability to rotate the body in space resulted in reduction, but not elimination, of the effect. The effect was present in quiet standing and even in sitting postures where locomotion was not possible. The robust transfer of PKAR to non-locomotor tasks, and across locomotor forms as demonstrated previously, is in contrast to split-belt adaptations that show limited transfer. We propose that, unlike split-belt adaptations, podokinetic adaptations are mediated at supraspinal, spatial orientation areas that influences spinal-level circuits for locomotion. PMID:21076818

  15. Seismic anisotropy and its precursory change before eruptions at Piton de la Fournaise volcano, La Réunion

    NASA Astrophysics Data System (ADS)

    Savage, M. K.; Ferrazzini, V.; Peltier, A.; Rivemale, E.; Mayor, J.; Schmid, A.; Brenguier, F.; Massin, F.; Got, J.-L.; Battaglia, J.; DiMuro, A.; Staudacher, T.; Rivet, D.; Taisne, B.; Shelley, A.

    2015-05-01

    The Piton de la Fournaise volcano exhibits frequent eruptions preceded by seismic swarms and is a good target to test hypotheses about magmatically induced variations in seismic wave properties. We use a permanent station network and a portable broadband network to compare seismic anisotropy measured via shear wave splitting with geodetic displacements, ratios of compressional to shear velocity (Vp/Vs), earthquake focal mechanisms, and ambient noise correlation analysis of surface wave velocities and to examine velocity and stress changes from 2000 through 2012. Fast directions align radially to the central cone and parallel to surface cracks and fissures, suggesting stress-controlled cracks. High Vp/Vs ratios under the summit compared with low ratios under the flank suggest spatial variations in the proportion of fluid-filled versus gas-filled cracks. Secular variations of fast directions (ϕ) and delay times (dt) between split shear waves are interpreted to sense changing crack densities and pressure. Delay times tend to increase while surface wave velocity decreases before eruptions. Rotations of ϕ may be caused by changes in either stress direction or fluid pressure. These changes usually correlate with GPS baseline changes. Changes in shear wave splitting measurements made on multiplets yield several populations with characteristic delay times, measured incoming polarizations, and fast directions, which change their proportion as a function of time. An eruption sequence on 14 October 2010 yielded over 2000 shear wave splitting measurements in a 14 h period, allowing high time resolution measurements to characterize the sequence. Stress directions from a propagating dike model qualitatively fit the temporal change in splitting.

  16. Locomotor adaptability in persons with unilateral transtibial amputation.

    PubMed

    Darter, Benjamin J; Bastian, Amy J; Wolf, Erik J; Husson, Elizabeth M; Labrecque, Bethany A; Hendershot, Brad D

    2017-01-01

    Locomotor adaptation enables walkers to modify strategies when faced with challenging walking conditions. While a variety of neurological injuries can impair locomotor adaptability, the effect of a lower extremity amputation on adaptability is poorly understood. Determine if locomotor adaptability is impaired in persons with unilateral transtibial amputation (TTA). The locomotor adaptability of 10 persons with a TTA and 8 persons without an amputation was tested while walking on a split-belt treadmill with the parallel belts running at the same (tied) or different (split) speeds. In the split condition, participants walked for 15 minutes with the respective belts moving at 0.5 m/s and 1.5 m/s. Temporal spatial symmetry measures were used to evaluate reactive accommodations to the perturbation, and the adaptive/de-adaptive response. Persons with TTA and the reference group of persons without amputation both demonstrated highly symmetric walking at baseline. During the split adaptation and tied post-adaptation walking both groups responded with the expected reactive accommodations. Likewise, adaptive and de-adaptive responses were observed. The magnitude and rate of change in the adaptive and de-adaptive responses were similar for persons with TTA and those without an amputation. Furthermore, adaptability was no different based on belt assignment for the prosthetic limb during split adaptation walking. Reactive changes and locomotor adaptation in response to a challenging and novel walking condition were similar in persons with TTA to those without an amputation. Results suggest persons with TTA have the capacity to modify locomotor strategies to meet the demands of most walking conditions despite challenges imposed by an amputation and use of a prosthetic limb.

  17. Split Bregman multicoil accelerated reconstruction technique: A new framework for rapid reconstruction of cardiac perfusion MRI

    PubMed Central

    Kamesh Iyer, Srikant; Tasdizen, Tolga; Likhite, Devavrat; DiBella, Edward

    2016-01-01

    Purpose: Rapid reconstruction of undersampled multicoil MRI data with iterative constrained reconstruction method is a challenge. The authors sought to develop a new substitution based variable splitting algorithm for faster reconstruction of multicoil cardiac perfusion MRI data. Methods: The new method, split Bregman multicoil accelerated reconstruction technique (SMART), uses a combination of split Bregman based variable splitting and iterative reweighting techniques to achieve fast convergence. Total variation constraints are used along the spatial and temporal dimensions. The method is tested on nine ECG-gated dog perfusion datasets, acquired with a 30-ray golden ratio radial sampling pattern and ten ungated human perfusion datasets, acquired with a 24-ray golden ratio radial sampling pattern. Image quality and reconstruction speed are evaluated and compared to a gradient descent (GD) implementation and to multicoil k-t SLR, a reconstruction technique that uses a combination of sparsity and low rank constraints. Results: Comparisons based on blur metric and visual inspection showed that SMART images had lower blur and better texture as compared to the GD implementation. On average, the GD based images had an ∼18% higher blur metric as compared to SMART images. Reconstruction of dynamic contrast enhanced (DCE) cardiac perfusion images using the SMART method was ∼6 times faster than standard gradient descent methods. k-t SLR and SMART produced images with comparable image quality, though SMART was ∼6.8 times faster than k-t SLR. Conclusions: The SMART method is a promising approach to reconstruct good quality multicoil images from undersampled DCE cardiac perfusion data rapidly. PMID:27036592

  18. Band positions of Rutile surfaces and the possibility of water splitting

    NASA Astrophysics Data System (ADS)

    Esch, Tobit R.; Bredow, Thomas

    2017-11-01

    It is well known that both the band gap and the band edge positions of oxide semiconductors are important for the photocatalytic water splitting. In this study, we show that different surface terminations of the same crystalline solid lead to considerable variations of the band gaps and band edges. As an example, we investigate the low-index surfaces of rutile TiO2. A series of hybrid methods based on the PBE exchange-correlation functional, PBE0, HSE06 and HISS, are employed to study the effect of long-range exchange on the electronic properties. In aqueous solution, the oxide particles employed in photocatalysis are fully covered with water molecules. We therefore study the influence of molecularly and dissociatively adsorbed water on the band positions. It is found that water adsorption leads to significant shifts of the band edge positions due to changes of the electrostatic potential at the surface atom positions.

  19. Mixing Of Mode Symmetries In Top Gated Bilayer And Multilayer Graphene Field Effect Devices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chakraborty, Biswanath; Das, Anindya; Sood, A. K.

    2011-07-15

    We report Raman study to investigate the influence of stacking on the inversion symmetry breaking in top gated bi- and multi-layer ({approx}10 layers) graphene field effect transistors. The G phonon mode splits into a low frequency (G{sub low}) and a high frequency (G{sub high}) mode in bi- and multi-layer graphene and the two modes show different dependence on doping. The mode splitting is explained in terms of mixing of zone-center in-plane optical phonons representing in-phase and out-of-phase inter-layer atomic motions. Unlike in bilayer graphene, there is no transfer of intensity from G{sub low} to G{sub high} in multilayer graphene. Amore » comparison is made for the bilayer graphene data with the recent theory of Gava et al. [Phys. Rev. B 80, 155422 (2009)].« less

  20. Possible influence of the Kuramoto length in a photo-catalytic water splitting reaction revealed by Poisson-Nernst-Planck equations involving ionization in a weak electrolyte

    NASA Astrophysics Data System (ADS)

    Suzuki, Yohichi; Seki, Kazuhiko

    2018-03-01

    We studied ion concentration profiles and the charge density gradient caused by electrode reactions in weak electrolytes by using the Poisson-Nernst-Planck equations without assuming charge neutrality. In weak electrolytes, only a small fraction of molecules is ionized in bulk. Ion concentration profiles depend on not only ion transport but also the ionization of molecules. We considered the ionization of molecules and ion association in weak electrolytes and obtained analytical expressions for ion densities, electrostatic potential profiles, and ion currents. We found the case that the total ion density gradient was given by the Kuramoto length which characterized the distance over which an ion diffuses before association. The charge density gradient is characterized by the Debye length for 1:1 weak electrolytes. We discuss the role of these length scales for efficient water splitting reactions using photo-electrocatalytic electrodes.

  1. Analysis of X-ray adsorption edges: L 2,3 edge of FeCl 4 -

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bagus, Paul S.; Nelin, Connie J.; Ilton, Eugene S.

    We describe a detailed analysis of the features of the X-ray adsorption spectra at the Fe L 2,3 edge of FeCl 4. The objective of this analysis is to explain the origin of the complex features in relation to properties of the wavefunctions, especially for the excited states. These properties include spin-orbit and ligand field splittings where a novel aspect of the dipole selection rules is applied to understand the influence of these splittings on the spectra. We also explicitly take account of the intermediate coupling of the open core and valence shell electrons. Our analysis also includes comparison ofmore » theory and experiment for the Fe L 2,3 edge and comparison of theoretical predictions for the Fe 3+ cation and FeCl 4-. The electronic structure is obtained from theoretical wavefunctions for the ground and excited states.« less

  2. Zero-field splitting in the isoelectronic aqueous Gd(III) and Eu(II) complexes from a first principles analysis

    NASA Astrophysics Data System (ADS)

    Khan, S.; Peters, V.; Kowalewski, J.; Odelius, M.

    2018-03-01

    The zero-field splitting (ZFS) of the ground state octet in aqueous Eu(II) and Gd(III) solutions was investigated through multi- configurational quantum chemical calculations and ab initio molecular dynamics (AIMD) simulations. Investigation of the ZFS of the lanthanide ions is essential to understand the electron spin dynamics and nuclear spin relaxation around paramagnetic ions and consequently the mechanisms underlying applications like magnetic resonance imaging. We found by comparing clusters at identical geometries but different metallic centres that there is not a simple relationship for their ZFS, in spite of the complexes being isoelectronic - each containing 7 unpaired f electrons. Through sampling it was established that inclusion of the first hydration shell has a dominant (over 90 %) influence on the ZFS. Extended sampling of aqueous Gd(III) showed that the 2 nd order spin Hamiltonian formalism is valid and that the rhombic ZFS component is decisive.

  3. Electric Grid Expansion Planning with High Levels of Variable Generation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hadley, Stanton W.; You, Shutang; Shankar, Mallikarjun

    2016-02-01

    Renewables are taking a large proportion of generation capacity in U.S. power grids. As their randomness has increasing influence on power system operation, it is necessary to consider their impact on system expansion planning. To this end, this project studies the generation and transmission expansion co-optimization problem of the US Eastern Interconnection (EI) power grid with a high wind power penetration rate. In this project, the generation and transmission expansion problem for the EI system is modeled as a mixed-integer programming (MIP) problem. This study analyzed a time series creation method to capture the diversity of load and wind powermore » across balancing regions in the EI system. The obtained time series can be easily introduced into the MIP co-optimization problem and then solved robustly through available MIP solvers. Simulation results show that the proposed time series generation method and the expansion co-optimization model and can improve the expansion result significantly after considering the diversity of wind and load across EI regions. The improved expansion plan that combines generation and transmission will aid system planners and policy makers to maximize the social welfare. This study shows that modelling load and wind variations and diversities across balancing regions will produce significantly different expansion result compared with former studies. For example, if wind is modeled in more details (by increasing the number of wind output levels) so that more wind blocks are considered in expansion planning, transmission expansion will be larger and the expansion timing will be earlier. Regarding generation expansion, more wind scenarios will slightly reduce wind generation expansion in the EI system and increase the expansion of other generation such as gas. Also, adopting detailed wind scenarios will reveal that it may be uneconomic to expand transmission networks for transmitting a large amount of wind power through a long distance in the EI system. Incorporating more details of renewables in expansion planning will inevitably increase the computational burden. Therefore, high performance computing (HPC) techniques are urgently needed for power system operation and planning optimization. As a scoping study task, this project tested some preliminary parallel computation techniques such as breaking down the simulation task into several sub-tasks based on chronology splitting or sample splitting, and then assigning these sub-tasks to different cores. Testing results show significant time reduction when a simulation task is split into several sub-tasks for parallel execution.« less

  4. ["In-situ split" (ISS) liver resection: new aspects of technique and indication].

    PubMed

    Lang, S A; Loss, M; Schlitt, H J

    2014-04-01

    The combination of right portal vein ligation with complete parenchyma dissection ("in-situ split", ISS) for rapid hypertrophy induction of the left-lateral liver lobe is a novel strategy to convert primarily irresectable liver tumours into a resectable stage. Available data so far show a 60-80 % growth induction of the remnant liver within 7(- 9) days. Certainly, a novel concept that comprises two operations within a very short time period raises questions. Based on the very few literature reports that have been published so far, as well as our own experience, we here discuss technical issues such as the use of a plastic sheet on the resection margin, the possibility of laparoscopic dissection and the timing of the second operation. Moreover, aspects of the preoperative diagnostic work-up that is necessary are assessed. Finally, open questions, e.g., concerning the influence of preoperative chemotherapy and the use of ISS in patients with cirrhosis are evaluated. In summary, the assessment of chances and risks of this novel concept with regard to indication and technical issues helps to provide the potentially curative option of the "in-situ split" procedure to more patients with marginal or even irresectable liver tumours. Georg Thieme Verlag KG Stuttgart · New York.

  5. Inter-band optoelectronic properties in quantum dot structure of low band gap III-V semiconductors

    NASA Astrophysics Data System (ADS)

    Dey, Anup; Maiti, Biswajit; Chanda Sarkar, Debasree

    2014-04-01

    A generalized theory is developed to study inter-band optical absorption coefficient (IOAC) and material gain (MG) in quantum dot structures of narrow gap III-V compound semiconductor considering the wave-vector (k→) dependence of the optical transition matrix element. The band structures of these low band gap semiconducting materials with sufficiently separated split-off valance band are frequently described by the three energy band model of Kane. This has been adopted for analysis of the IOAC and MG taking InAs, InSb, Hg1-xCdxTe, and In1-xGaxAsyP1-y lattice matched to InP, as example of III-V compound semiconductors, having varied split-off energy band compared to their bulk band gap energy. It has been found that magnitude of the IOAC for quantum dots increases with increasing incident photon energy and the lines of absorption are more closely spaced in the three band model of Kane than those with parabolic energy band approximations reflecting the direct the influence of energy band parameters. The results show a significant deviation to the MG spectrum of narrow-gap materials having band nonparabolicity compared to the parabolic band model approximations. The results reflect the important role of valence band split-off energies in these narrow gap semiconductors.

  6. Oceanic dispersal, vicariance and human introduction shaped the modern distribution of the termites Reticulitermes, Heterotermes and Coptotermes.

    PubMed

    Bourguignon, Thomas; Lo, Nathan; Šobotník, Jan; Sillam-Dussès, David; Roisin, Yves; Evans, Theodore A

    2016-03-30

    Reticulitermes, Heterotermes and Coptotermes form a small termite clade with partly overlapping distributions. Although native species occur across all continents, the factors influencing their distribution are poorly known. Here, we reconstructed the historical biogeography of these termites using mitochondrial genomes of species collected on six continents. Our analyses showed that Reticulitermes split from Heterotermes + Coptotermesat 59.5 Ma (49.9-69.5 Ma 95% CI), yet the oldest split within Reticulitermes(Eurasia and North America) is 16.1 Ma (13.4-19.5 Ma) and the oldest split within Heterotermes + Coptotermesis 36.0 Ma (33.9-40.5 Ma). We detected 14 disjunctions between biogeographical realms, all of which occurred within the last 34 Ma, not only after the break-up of Pangaea, but also with the continents in similar to current positions. Land dispersal over land bridges explained four disjunctions, oceanic dispersal by wood rafting explained eight disjunctions, and human introduction was the source of two recent disjunctions. These wood-eating termites, therefore, appear to have acquired their modern worldwide distribution through multiple dispersal processes, with oceanic dispersal and human introduction favoured by the ecological traits of nesting in wood and producing replacement reproductives. © 2016 The Author(s).

  7. Oceanic dispersal, vicariance and human introduction shaped the modern distribution of the termites Reticulitermes, Heterotermes and Coptotermes

    PubMed Central

    Bourguignon, Thomas; Lo, Nathan; Šobotník, Jan; Sillam-Dussès, David; Roisin, Yves; Evans, Theodore A.

    2016-01-01

    Reticulitermes, Heterotermes and Coptotermes form a small termite clade with partly overlapping distributions. Although native species occur across all continents, the factors influencing their distribution are poorly known. Here, we reconstructed the historical biogeography of these termites using mitochondrial genomes of species collected on six continents. Our analyses showed that Reticulitermes split from Heterotermes + Coptotermes at 59.5 Ma (49.9–69.5 Ma 95% CI), yet the oldest split within Reticulitermes (Eurasia and North America) is 16.1 Ma (13.4–19.5 Ma) and the oldest split within Heterotermes + Coptotermes is 36.0 Ma (33.9–40.5 Ma). We detected 14 disjunctions between biogeographical realms, all of which occurred within the last 34 Ma, not only after the break-up of Pangaea, but also with the continents in similar to current positions. Land dispersal over land bridges explained four disjunctions, oceanic dispersal by wood rafting explained eight disjunctions, and human introduction was the source of two recent disjunctions. These wood-eating termites, therefore, appear to have acquired their modern worldwide distribution through multiple dispersal processes, with oceanic dispersal and human introduction favoured by the ecological traits of nesting in wood and producing replacement reproductives. PMID:27030416

  8. A hybrid 3D spatial access method based on quadtrees and R-trees for globe data

    NASA Astrophysics Data System (ADS)

    Gong, Jun; Ke, Shengnan; Li, Xiaomin; Qi, Shuhua

    2009-10-01

    3D spatial access method for globe data is very crucial technique for virtual earth. This paper presents a brand-new maintenance method to index 3d objects distributed on the whole surface of the earth, which integrates the 1:1,000,000- scale topographic map tiles, Quad-tree and R-tree. Furthermore, when traditional methods are extended into 3d space, the performance of spatial index deteriorates badly, for example 3D R-tree. In order to effectively solve this difficult problem, a new algorithm of dynamic R-tree is put forward, which includes two sub-procedures, namely node-choosing and node-split. In the node-choosing algorithm, a new strategy is adopted, not like the traditional mode which is from top to bottom, but firstly from bottom to top then from top to bottom. This strategy can effectively solve the negative influence of node overlap. In the node-split algorithm, 2-to-3 split mode substitutes the traditional 1-to-2 mode, which can better concern the shape and size of nodes. Because of the rational tree shape, this R-tree method can easily integrate the concept of LOD. Therefore, it will be later implemented in commercial DBMS and adopted in time-crucial 3d GIS system.

  9. Oriented epitaxial TiO2 nanowires for water splitting

    NASA Astrophysics Data System (ADS)

    Hou, Wenting; Cortez, Pablo; Wuhrer, Richard; Macartney, Sam; Bozhilov, Krassimir N.; Liu, Rong; Sheppard, Leigh R.; Kisailus, David

    2017-06-01

    Highly oriented epitaxial rutile titanium dioxide (TiO2) nanowire arrays have been hydrothermally grown on polycrystalline TiO2 templates with their orientation dependent on the underlying TiO2 grain. Both the diameter and areal density of the nanowires were tuned by controlling the precursor concentration, and the template surface energy and roughness. Nanowire tip sharpness was influenced by precursor solubility and diffusivity. A new secondary ion mass spectrometer technique has been developed to install additional nucleation sites in single crystal TiO2 templates and the effect on nanowire growth was probed. Using the acquired TiO2 nanowire synthesis knowhow, an assortment of nanowire arrays were installed upon the surface of undoped TiO2 photo-electrodes and assessed for their photo-electrochemical water splitting performance. The key result obtained was that the presence of short and dispersed nanowire arrays significantly improved the photocurrent when the illumination intensity was increased from 100 to 200 mW cm-2. This is attributed to the alignment of the homoepitaxially grown nanowires to the [001] direction, which provides the fastest charge transport in TiO2 and an improved pathway for photo-holes to find water molecules and undertake oxidation. This result lays a foundation for achieving efficient water splitting under conditions of concentrated solar illumination.

  10. Cooper pair splitter realized in a two-quantum-dot Y-junction.

    PubMed

    Hofstetter, L; Csonka, S; Nygård, J; Schönenberger, C

    2009-10-15

    Non-locality is a fundamental property of quantum mechanics that manifests itself as correlations between spatially separated parts of a quantum system. A fundamental route for the exploration of such phenomena is the generation of Einstein-Podolsky-Rosen (EPR) pairs of quantum-entangled objects for the test of so-called Bell inequalities. Whereas such experimental tests of non-locality have been successfully conducted with pairwise entangled photons, it has not yet been possible to realize an electronic analogue of it in the solid state, where spin-1/2 mobile electrons are the natural quantum objects. The difficulty stems from the fact that electrons are immersed in a macroscopic ground state-the Fermi sea-which prevents the straightforward generation and splitting of entangled pairs of electrons on demand. A superconductor, however, could act as a source of EPR pairs of electrons, because its ground-state is composed of Cooper pairs in a spin-singlet state. These Cooper pairs can be extracted from a superconductor by tunnelling, but, to obtain an efficient EPR source of entangled electrons, the splitting of the Cooper pairs into separate electrons has to be enforced. This can be achieved by having the electrons 'repel' each other by Coulomb interaction. Controlled Cooper pair splitting can thereby be realized by coupling of the superconductor to two normal metal drain contacts by means of individually tunable quantum dots. Here we demonstrate the first experimental realization of such a tunable Cooper pair splitter, which shows a surprisingly high efficiency. Our findings open a route towards a first test of the EPR paradox and Bell inequalities in the solid state.

  11. Locking plate fixation provides superior fixation of humerus split type greater tuberosity fractures than tension bands and double row suture bridges.

    PubMed

    Gaudelli, Cinzia; Ménard, Jérémie; Mutch, Jennifer; Laflamme, G-Yves; Petit, Yvan; Rouleau, Dominique M

    2014-11-01

    This paper aims to determine the strongest fixation method for split type greater tuberosity fractures of the proximal humerus by testing and comparing three fixation methods: a tension band with No. 2 wire suture, a double-row suture bridge with suture anchors, and a manually contoured calcaneal locking plate. Each method was tested on eight porcine humeri. A osteotomy of the greater tuberosity was performed 50° to the humeral shaft and then fixed according to one of three methods. The humeri were then placed in a testing apparatus and tension was applied along the supraspinatus tendon using a thermoelectric cooling clamp. The load required to produce 3mm and 5mm of displacement, as well as complete failure, was recorded using an axial load cell. The average load required to produce 3mm and 5mm of displacement was 658N and 1112N for the locking plate, 199N and 247N for the double row, and 75N and 105N for the tension band. The difference between the three groups was significant (P<0.01). The average load to failure of the locking plate (810N) was significantly stronger than double row (456N) and tension band (279N) (P<0.05). The stiffness of the locking plate (404N/mm) was significantly greater than double row (71N/mm) and tension band (33N/mm) (P<0.01). Locking plate fixation provides the strongest and stiffest biomechanical fixation for split type greater tuberosity fractures. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Algebraic techniques for diagonalization of a split quaternion matrix in split quaternionic mechanics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jiang, Tongsong, E-mail: jiangtongsong@sina.com; Department of Mathematics, Heze University, Heze, Shandong 274015; Jiang, Ziwu

    In the study of the relation between complexified classical and non-Hermitian quantum mechanics, physicists found that there are links to quaternionic and split quaternionic mechanics, and this leads to the possibility of employing algebraic techniques of split quaternions to tackle some problems in complexified classical and quantum mechanics. This paper, by means of real representation of a split quaternion matrix, studies the problem of diagonalization of a split quaternion matrix and gives algebraic techniques for diagonalization of split quaternion matrices in split quaternionic mechanics.

  13. Design of a factorial experiment with randomization restrictions to assess medical device performance on vascular tissue

    PubMed Central

    2011-01-01

    Background Energy-based surgical scalpels are designed to efficiently transect and seal blood vessels using thermal energy to promote protein denaturation and coagulation. Assessment and design improvement of ultrasonic scalpel performance relies on both in vivo and ex vivo testing. The objective of this work was to design and implement a robust, experimental test matrix with randomization restrictions and predictive statistical power, which allowed for identification of those experimental variables that may affect the quality of the seal obtained ex vivo. Methods The design of the experiment included three factors: temperature (two levels); the type of solution used to perfuse the artery during transection (three types); and artery type (two types) resulting in a total of twelve possible treatment combinations. Burst pressures of porcine carotid and renal arteries sealed ex vivo were assigned as the response variable. Results The experimental test matrix was designed and carried out as a split-plot experiment in order to assess the contributions of several variables and their interactions while accounting for randomization restrictions present in the experimental setup. The statistical software package SAS was utilized and PROC MIXED was used to account for the randomization restrictions in the split-plot design. The combination of temperature, solution, and vessel type had a statistically significant impact on seal quality. Conclusions The design and implementation of a split-plot experimental test-matrix provided a mechanism for addressing the existing technical randomization restrictions of ex vivo ultrasonic scalpel performance testing, while preserving the ability to examine the potential effects of independent factors or variables. This method for generating the experimental design and the statistical analyses of the resulting data are adaptable to a wide variety of experimental problems involving large-scale tissue-based studies of medical or experimental device efficacy and performance. PMID:21599963

  14. StackSplit - a plugin for multi-event shear wave splitting analyses in SplitLab

    NASA Astrophysics Data System (ADS)

    Grund, Michael

    2017-08-01

    SplitLab is a powerful and widely used tool for analysing seismological shear wave splitting of single event measurements. However, in many cases, especially temporary station deployments close to the noisy seaside, ocean bottom or for recordings affected by strong anthropogenic noise, only multi-event approaches provide stable and reliable splitting results. In order to extend the original SplitLab environment for such analyses, I present the StackSplit plugin that can easily be implemented within the well accepted main program. StackSplit grants easy access to several different analysis approaches within SplitLab, including a new multiple waveform based inversion method as well as the most established standard stacking procedures. The possibility to switch between different analysis approaches at any time allows the user for the most flexible processing of individual multi-event splitting measurements for a single recording station. Besides the provided functions of the plugin, no other external program is needed for the multi-event analyses since StackSplit performs within the available SplitLab structure which is based on MATLAB. The effectiveness and use of this plugin is demonstrated with data examples of a long running seismological recording station in Finland.

  15. Change in reimbursement and costs in German oncological head and neck surgery over the last decade: ablative tongue cancer surgery and reconstruction with split-thickness skin graft vs. microvascular radial forearm flap.

    PubMed

    Hoefert, Sebastian; Lotter, Oliver

    2018-05-01

    Defects after ablative tongue cancer surgery can be reconstructed by split-thickness skin grafts or free microvascular flaps. The different surgical options may influence costs, reimbursement, and therefore possible profits. Our goal was to analyze the development of these parameters for different procedures in head and neck reconstruction in Germany over the last decade. After tumor resection and neck dissection of tongue cancer, three different scenarios were chosen to calculate costs, reimbursement, length of stay (LoS), and profits. Two options considered were reconstruction by split-thickness skin graft with (option Ia) and without (option Ib) tracheotomy. In addition, we analyzed microvascular reconstruction with radial forearm flap (option II). Furthermore, unsatisfactory results after options Ia and Ib may make secondary tongue plastic with split-thickness skin grafting necessary (option I+). The calculations were performed considering the German Diagnosis Related Group (DRG) system and compared to the specific DRG cost data of 250 German reference hospitals. The overall average length of stay (aLoS) declined from 16.7 to 12.8 days with a reduction in every option. Until 2011, all options showed similar accumulated DRG reimbursement. From 2012 onwards, earnings almost doubled for option II due to changes in the DRG allocation. As was expected, the highest costs were observed in option II. Profits (reimbursement minus costs) were also highest for option II (mean 2052 €, maximum 3630 Euros in 2015) followed by options Ia (765 €) and Ib/I+ (681 €). Average profits over time would be 17 to 19% higher if adjusted for inflation. We showed the development of the DRG allocation of two commonly used methods of reconstruction after ablative tongue cancer surgery and the associated LoS, reimbursement, costs, and profits. As expected, the highest values were found for microvascular reconstruction. Microvascular reconstruction may also be the primary choice of treatment from a medical point of view. However, prolonged operation times, intensive care, and hospital stay in connection with complex microvascular operations can easily turn profits into losses as opposed to the results of simple, reliable, and fast split-thickness skin grafting. The inflation rate influences profits in reimbursement systems where costs are based on a previous period of time. Surgeons find themselves daily in an area of conflict between economic interests and medical decision-making. Due to its multidimensional aspects, the choice of the reconstructive technique should be primarily based on the best medical care for the patient. But there should also be awareness of the economic risk of all three surgical procedures.

  16. Predicting Job Performance for the Visually Impaired: Validity of the Fine Finger Dexterity Work Task.

    ERIC Educational Resources Information Center

    Giesen, J. Martin; And Others

    The study was designed to determine the reliability and criterion validity of a psychomotor performance test (the Fine Finger Dexterity Work Task Unit) with 40 partially or totally blind adults. Reliability was established by using the test-retest method. A supervisory rating was developed and the reliability established by using the split-half…

  17. Impact of Steel Fiber Size and Shape on the Mechanical Properties of Ultra-High Performance Concrete

    DTIC Science & Technology

    2015-08-01

    32 Appendix B: DTT Specimens Pretest / Posttest ..................................................................................... 36 Appendix C...type and then subsequently compared to that material’s UCS. Figure 6 shows the splitting tensile testing set-up, both pretest and posttest . Figure...9 show the actual test configuration, pretest and posttest , respectively. This configuration utilized a chucking mechanism suited to the shape of

  18. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT, PHYSICAL REMOVAL OF MICROBIAL CONTAMINATION AGENTS IN DRINKING WATER, ECOWATER SYSTEMS, INC., SEARS KENMORE ULTRAFILTER 500 DRINKING WATER TREATMENT SYSTEM (POU)

    EPA Science Inventory

    The Sears Kenmore Ultrafilter 500 RO system was tested for removal of bacteria and viruses at NSF International's Drinking Water Treatment Systems Laboratory. EcoWater Systems submitted ten units for testing, which were split into two groups of five. One group received 25 days ...

  19. Mechanical properties of wood

    Treesearch

    David W. Green; Jerrold E. Winandy; David E. Kretschmann

    1999-01-01

    The mechanical properties presented in this chapter were obtained from tests of small pieces of wood termed “clear” and “straight grained” because they did not contain characteristics such as knots, cross grain, checks, and splits. These test pieces did have anatomical characteristics such as growth rings that occurred in consistent patterns within each piece. Clear...

  20. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - PHYSICAL REMOVAL OF MICROBIAL CONTAMINATION AGENTS IN DRINKING WATER, WATTS P{REMIER ULTRA 5 REVERSE OSMOSIS DRINKING WATER TREATMENT SYSTEM (POU)

    EPA Science Inventory

    The Watts Premier Ultra 5 system was tested for removal of bacteria and viruses at NSF International's Laboratory. Watts Premier submitted ten units, which were split into two groups of five. One group received 25 days of conditioning prior to challenge testing, while the secon...

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