46 CFR 7.95 - St. Johns Point, FL to Miami Beach, FL.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 1 2010-10-01 2010-10-01 false St. Johns Point, FL to Miami Beach, FL. 7.95 Section 7... LINES Atlantic Coast § 7.95 St. Johns Point, FL to Miami Beach, FL. (a) A line drawn from the seaward extremity of St. Augustine Inlet north jetty to latitude 29°55′ N. longitude 81°15.3′ W. (St. Augustine...
78 FR 28877 - Changes in Flood Hazard Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-16
... Sebastian St. Augustine, FL View, St. 32084. Augustine, FL 32084. New Mexico: Bernalillo City of Albuquerque... 73102. Walker Avenue, 3rd Floor, Oklahoma City, OK 73102. Oklahoma Unincorporated The Honorable Ray...
8. Historic American Buildings Survey PHOTOCOPY ORIGINAL ARCHITECTS' DRAWING ...
8. Historic American Buildings Survey PHOTOCOPY -- ORIGINAL ARCHITECTS' DRAWING IN INK ON LINEN (ABOUT 3'-7'x2'-7 1/2') (C. 1889). ORIGINAL IN THE COLLECTION OF THE PRESBYTERIAN CHURCH, ST. AUGUSTINE, FLORIDA - Flagler Memorial Presbyterian Church, Valencia & Sevilla Streets, Saint Augustine, St. Johns County, FL
18. Historic American Buildings Survey PHOTOCOPY OF SKETCH BY FREDERIK ...
18. Historic American Buildings Survey PHOTOCOPY OF SKETCH BY FREDERIK GJESSING USED TO ILLUSTRATE HIS ARTICLE 'OBSERVATIONS ON THE OLDEST HOUSE, ST. AUGUSTINE,' (p.111) IN EVOLUTION OF THE OLDEST HOUSE TALLAHASSEE, FLORIDA: DEPARTMENT FLORIDA STATE UNIVERSITY, 1962 - Gonzalez-Alvarez House, 14 Saint Francis Street, Saint Augustine, St. Johns County, FL
St. Johns County, St. Augustine Inlet, FL, Report 1: Historical Analysis and Sediment Budget
2012-08-01
Anastasia Island ........................................................ 26 4.5 Alongshore region of influence of the inlet...profile T-129 from 1984 to 2010. ....................................................... 15 Figure 16. Ebb shoal bathymetry, Vilano and Anastasia Islands...2007. ............................................. 17 Figure 17. Ebb shoal bathymetry, Vilano and Anastasia Islands, 2008
35. OUTER DRAWBRIDGE, ENTRY TO THE PROTECTIVE CORRIDOR BETWEEN THE ...
35. OUTER DRAWBRIDGE, ENTRY TO THE PROTECTIVE CORRIDOR BETWEEN THE RAVELIN AND THE CASTILLO, AS SEEN FROM WITHIN THE CORRIDOR - Castillo de San Marcos, 1 Castillo Drive, Saint Augustine, St. Johns County, FL
75 FR 81892 - Changes in Flood Elevation Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-29
..., 500 San Sebastian View, St. Augustine, FL 32084. Hawaii: Hawaii (FEMA Docket No.: B- Unincorporated areas April 16, 2010; The Honorable William P. August 23, 2010 155166 1124) of Hawaii County (09- April 23, 2010; Kenoi, Mayor, Hawaii 09-1398P). Hawaii Tribune- County, 25 Aupuni Herald. Street, Hilo, HI...
ACHP | Working Together to Build a More Inclusive Preservation Program
Carl D. Halbirt, City Archaeologist, St. Augustine, Florida Carl D. Halbirt head shot (2013)--courtesy Daron Dean (The St. Augustine Record) Carl D. Halbirt head shot (2013)--courtesy Daron Dean (The St one of a series of historic monuments presented in the Plaza. Can you tell us what you are working on
Wave and Current Measurements From the Coastal Storms Program (CSP) Buoy 41012 off St. Augustine, FL
NASA Astrophysics Data System (ADS)
Crout, R. L.
2008-05-01
The Coastal Storms Program (CSP) is a NOAA program that involves several different branches within NOAA. Components of the National Ocean Service, the National Weather Service, the National Marine Fisheries Service, and the Office of Oceanic and Atmospheric Research participate in CSP, which is administered by the Coastal Services Center. CSP selects an area where an impact in support of the NOAA Societal Goals can be made. The first area selected was the northeast coast of Florida in 2002. In addition to coastal water level stations and modeling efforts, a 3-meter discuss buoy (WMO 41012) was deployed off the coast of St. Augustine, FL in approximately 38 meters of water. In addition to the normal complement of meteorological sensors, Buoy 41012 contained a sensor to measure directional waves at hourly intervals, a temperature-conductivity sensor to measure near-surface temperature and salinity, and a current profiler to obtain near-surface to near-bottom currents at hourly intervals. These data on the continental shelf provide a view of the oceanography on the inner margin of the Gulf Stream. The data are served over the National Data Buoy Center's web page and over the Global Telecommunications System. The waves and currents during the period from September 2005 through December 2007 are related to coastal storms, hurricanes, tides, and Gulf Stream intrusions. During several late fall and winter periods the waves exceeded 4.5 meters. The on-offshore component of the currents appears to be tidally driven, however, predominant on- and off-shore flows are observed in response to storms and Gulf Stream intrusions. The primary component of the flow is aligned alongshore and although the tidal influence is obvious, extended periods of northward and southward currents are observed. Currents approaching 2 knots are observed at various times during the period that the buoy has been active. The high currents appear to be in response to strong wind events (atmospheric frontal passages) and Gulf Stream intrusions.
NASA Technical Reports Server (NTRS)
Odle, W. C.
1976-01-01
Laboratory and field spectral reflectance measurements of healthy and infected St. Augustine grass were made using several different instruments. Spectral differences between healthy and infected grass occured in the visible and near infrared regions. Multiband and color infrared photographs were taken of healthy and diseased turf from ground-based platforms and low altitude aircraft. Qualitative (density slicing) and quantitative (transmission densitometry) analyses revealed distinct tonal differences between healthy and St. Augustine disease (SAD) infected grass. Similar experiments are described for determining if healthy and diseased grass can be distinguished from waterstressed grass and grass deficient in either nitrogen or iron.
Museum of Historic St. Augustine--Government House. Teacher's Guide.
ERIC Educational Resources Information Center
VanVleet, Susan; Spikes, Tracy
This booklet is designed to assist teachers in guiding students through the Museum of Historic St. Augustine (Government House) exhibit, "The Dream, The Challenge, The City." The exhibit and learning activities explore cultural, economic, and architectural development from the 1565 Spanish settlement to the Flagler Era of the 1880s and…
Healing the Wounds: St. Augustine, Catechesis, and Religious Education Today
ERIC Educational Resources Information Center
Franchi, Leonardo
2011-01-01
St. Augustine of Hippos' writing on education offers a fresh lens through which the conceptual framework of religious education in the Catholic school can be understood. Recent teaching of the Magisterium of the Catholic Church on the distinctive nature of religious education and catechesis has challenged religious educators to find an alternative…
St. Augustine and the Christian College Composition Classroom: Water into Flame
ERIC Educational Resources Information Center
Veach, Grace
2009-01-01
Today's Christian college students are more engaged in popular youth culture and less reflective than in the past. St. Augustine's On Christian Doctrine, Book IV, gives advice to preachers, but it can easily be adapted to apply to Christian college composition classrooms. The two main sections of the article cover how to teach and what to teach…
2012-08-01
Figure 6). Over the latter time period, from 1999 to 2007, Anastasia State Park experienced significant accretion where the region directly to the south...cu yd/year. However, a known reversal in net transport exists from the northern tip of Anastasia Island down to St. Augustine Beach, and the...connectivity. Therefore, the inlet left- bypassing location was set to the first adjacent cell. Downdrift of the inlet (to the right), the beach at Anastasia
Tsunamis generated by eruptions from mount st. Augustine volcano, alaska.
Kienle, J; Kowalik, Z; Murty, T S
1987-06-12
During an eruption of the Alaskan volcano Mount St. Augustine in the spring of 1986, there was concern about the possibility that a tsunami might be generated by the collapse of a portion of the volcano into the shallow water of Cook Inlet. A similar edifice collapse of the volcano and ensuing sea wave occurred during an eruption in 1883. Other sea waves resulting in great loss of life and property have been generated by the eruption of coastal volcanos around the world. Although Mount St. Augustine remained intact during this eruptive cycle, a possible recurrence of the 1883 events spurred a numerical simulation of the 1883 sea wave. This simulation, which yielded a forecast of potential wave heights and travel times, was based on a method that could be applied generally to other coastal volcanos.
Augustine the African: Critic of Roman Colonialist Discourse.
ERIC Educational Resources Information Center
Troup, Calvin L.
1995-01-01
Offers a reading of St. Augustine that suggests his work as prescient of, and harmonious with, contemporary criticism of colonialist discourse rather than as an authorizing voice for European imperialism. Looks also at a Stephen Greenblatt essay that comments on the relationship between Christianity and national lust for empire. (TB)
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-11
... Constitution Ave., Hartford, 12000359 Kensington Grammar School--Jean E. Hooker High School, 462 Alling St..., 12000365 St. Johns County Constitution Obelisk, Plaza de la Constitution, St. Augustine, 12000364 NEW YORK...
Manning, Liliann; Cassel, Daniel; Cassel, Jean-Christophe
2013-06-01
Reconstructing the past and anticipating the future, i.e., the ability of travelling in mental time, is thought to be at the heart of consciousness and, by the same token, at the center of human cognition. This extraordinary mental activity is possible thanks to the ability of being aware of 'subjective time'. In the present study, we attempt to trace back the first recorded reflections on the relations between time and memory, to the end of the fourth century's work, the Confessions, by the theologian and philosopher, St. Augustine. We concentrate on Book 11, where he extensively developed a series of articulated and detailed observations on memory and time. On the bases of selected paragraphs, we endeavor to highlight some concepts that may be considered as the product of the first or, at least, very early reflections related to our current notions of subjective time in mental time travel. We also draw a fundamental difference inherent to the frameworks within which the questions were raised. The contribution of St. Augustine on time and memory remains significant, notwithstanding the 16 centuries elapsed since it was made, likely because of the universality of its contents.
33 CFR 80.753 - St. Petersburg, FL to the Anclote, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false St. Petersburg, FL to the Anclote, FL. 80.753 Section 80.753 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Gulf Coast § 80.753 St. Petersburg, FL to...
33 CFR 80.750 - Sanibel Island, FL to St. Petersburg, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sanibel Island, FL to St. Petersburg, FL. 80.750 Section 80.750 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... St. Petersburg, FL. (a) A line formed by the centerline of the highway bridge over Blind Pass...
Cassel, Jean-Christophe; Cassel, Daniel; Manning, Lilianne
2013-03-01
Over the last half century, neuropsychologists, cognitive psychologists and cognitive neuroscientists interested in human memory have accumulated evidence showing that there is not one general memory function but a variety of memory systems deserving distinct (but for an organism, complementary) functional entities. The first attempts to organize memory systems within a taxonomic construct are often traced back to the French philosopher Maine de Biran (1766-1824), who, in his book first published in 1803, distinguished mechanical memory, sensitive memory and representative memory, without, however, providing any experimental evidence in support of his view. It turns out, however, that what might be regarded as the first elaborated taxonomic proposal is 14 centuries older and is due to Augustine of Hippo (354-430), also named St Augustine, who, in Book 10 of his Confessions, by means of an introspective process that did not aim at organizing memory systems, nevertheless distinguished and commented on sensible memory, intellectual memory, memory of memories, memory of feelings and passion, and memory of forgetting. These memories were envisaged as different and complementary instances. In the current study, after a short biographical synopsis of St Augustine, we provide an outline of the philosopher's contribution, both in terms of questions and answers, and focus on how this contribution almost perfectly fits with several viewpoints of modern psychology and neuroscience of memory about human memory functions, including the notion that episodic autobiographical memory stores events of our personal history in their what, where and when dimensions, and from there enables our mental time travel. It is not at all meant that St Augustine's elaboration was the basis for the modern taxonomy, but just that the similarity is striking, and that the architecture of our current viewpoints about memory systems might have preexisted as an outstanding intuition in the philosopher's mind.
33 CFR 80.810 - Cape San Blas, FL to Perdido Bay, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
..., FL to Perdido Bay, FL. (a) A line drawn from St. Joseph Bay Entrance Range A Rear Light through St. Joseph Bay Entrance Range B Front Light to St. Joseph Point. (b) A line drawn across the mouth of Salt Creek as an extension of the general trend of the shoreline to continue across the inlet to St. Andrews...
Descartes' visit to the town library, or how Augustinian is Descartes' neurophysiology?
Smith, C U
1998-08-01
Rene Descartes was early accused of taking his central philosophical proposition from St Augustine. Did he also take his central neurophysiological concept from the same source? This is the question which this paper sets out to answer. It is concluded that the foundational neurophysiology propounded in L'Homme does indeed show strong and interesting resemblences to Augustine's largely Erasistratean version. Descartes, however, working within the new paradigm of seventeenth-century physical science, introduced a new principle: whereas Augustine's neurophysiology is pervaded throughout by a vital factor, the pneuma, Descartes' theory involved only inanimate material forces. It is concluded, further, that in spite of the interesting similarities between Augustinian and Cartesian neurophysiology there is no evidence for any direct plagiarism. It seems more likely that Augustine's influence was filtered through the Galenical physiologists of Descartes' own time and of the preceding century.
33 CFR 117.261 - Atlantic Intracoastal Waterway from St. Marys River to Key Largo.
Code of Federal Regulations, 2010 CFR
2010-07-01
... from St. Marys River to Key Largo. 117.261 Section 117.261 Navigation and Navigable Waters COAST GUARD....261 Atlantic Intracoastal Waterway from St. Marys River to Key Largo. (a) General. Public vessels of..., mile 777.9 at St. Augustine. The draw shall open on signal; except that, from 7 a.m. to 6 p.m. the draw...
77 FR 51470 - Drawbridge Operation Regulations; Gulf Intracoastal Waterway, St. Petersburg/Tampa, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-24
... Operation Regulations; Gulf Intracoastal Waterway, St. Petersburg/Tampa, FL AGENCY: Coast Guard, DHS. ACTION... from the operating schedules that govern seven bridges in St. Petersburg and Tampa, Florida. The... Sector St Petersburg, FL has requested temporary modifications to the operating schedules of seven...
33 CFR 100.728 - Special Local Regulations; Hurricane Offshore Classic, St. Petersburg, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
...; Hurricane Offshore Classic, St. Petersburg, FL. 100.728 Section 100.728 Navigation and Navigable Waters... WATERS § 100.728 Special Local Regulations; Hurricane Offshore Classic, St. Petersburg, FL. (a) Regulated... commander designated by Coast Guard Sector St. Petersburg, Florida. (2) Spectator craft will be permitted...
Representations of eyeglasses on Gothic winged altars in Austria.
Daxecker, F
1997-01-01
The oldest representation of eyeglasses in the German-speaking area is found on the altar of Tyrol Castle in the Museum Ferdinandeum in Innsbruck, Tyrol, on an altarpiece depicting the death of the Virgin Mary (1370-1372). Other representations of eyeglasses are found in Klosterneuburg, Lower Austria, Albrechtsaltar, collegiate collection, death of the Virgin (1439); St. Lorenzen ob Murau, daughter church St. Lorenzen, Styria, Katharinenaltar, Disputation (1455-1460); Pettau (Ptuj), Pokrajinjski Muzej, Slovenia (then belonging to the archbishopric of Salzburg), Conrad Laib, St. Bernardine of Siena with a spectacle case (1460-1465); on two altars by Michael Pacher: Pharisee, Gries near Bolzano (1471-1475), apostle mourning over the death of the Virgin Mary, and St. Luke, St. Wolfgang in Salzkammergut (1481); St. Florian, Upper Austria, collegiate collection, altar of the provost Leonhard Riesenschmid of St. Florian, death of the Virgin (1487); museum of Wilten monastery, Innsbruck, Ludwig Konraiter, St. Ottilie with reading stones and death of the Virgin Mary with reading apostle (1485-1490); Austrian Gallery Belvedere, Vienna, Master of Grossgmain, St. Augustine (1498); Austrian Gallery Belvedere, Vienna, Master of Mondsee, St. Augustine (1490-1500); Diocesan museum Graz, Styria, altar of Hirschegg, death of the Virgin (1503); Krenstetten, Lower Austria, Stefan-Altar, Disputation (1500-1520); Museum Ferdinandeum, Innsbruck, Matheis Stöberl, Jesus and the scribes with a spectacle case (early 16th century).
46 CFR 7.85 - St. Simons Island, GA to Little Talbot Island, FL.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 1 2010-10-01 2010-10-01 false St. Simons Island, GA to Little Talbot Island, FL. 7.85... BOUNDARY LINES Atlantic Coast § 7.85 St. Simons Island, GA to Little Talbot Island, FL. (a) A line drawn from latitude 31°04.1′ N. longitude 81°16.7′ W. (St. Simons Lighted Whistle Buoy “ST S”) to latitude 30...
46 CFR 7.90 - St. Johns River, FL.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 1 2010-10-01 2010-10-01 false St. Johns River, FL. 7.90 Section 7.90 Shipping COAST... § 7.90 St. Johns River, FL. A line drawn from the southeasternmost extremity of Little Talbot (Spike) Island to latitude 30°23.8′ N. longitude 81°20.3′ W. (St. Johns Lighted Whistle Buoy “2 STJ”); thence to...
ERIC Educational Resources Information Center
Ross, Janell
2006-01-01
This article reveals the disturbing truths uncovered by a retired biology professor about the past practices of a North Carolina hospital. In the 1990s, Irene Clark was a biology professor at St. Augustine's College, a historically Black college in Raleigh, North Carolina. One day, a janitor asked the native Virginian what she knew about the…
33 CFR 100.728 - Special Local Regulations; Hurricane Offshore Classic, St. Petersburg, FL.
Code of Federal Regulations, 2013 CFR
2013-07-01
...; Hurricane Offshore Classic, St. Petersburg, FL. 100.728 Section 100.728 Navigation and Navigable Waters... WATERS § 100.728 Special Local Regulations; Hurricane Offshore Classic, St. Petersburg, FL. (a) Regulated..., from 10 a.m. to 6 p.m. EDT. (3) All vessel traffic, not involved in the Hurricane Offshore Classic...
33 CFR 100.728 - Special Local Regulations; Hurricane Offshore Classic, St. Petersburg, FL.
Code of Federal Regulations, 2011 CFR
2011-07-01
...; Hurricane Offshore Classic, St. Petersburg, FL. 100.728 Section 100.728 Navigation and Navigable Waters... WATERS § 100.728 Special Local Regulations; Hurricane Offshore Classic, St. Petersburg, FL. (a) Regulated..., from 10 a.m. to 6 p.m. EDT. (3) All vessel traffic, not involved in the Hurricane Offshore Classic...
33 CFR 100.728 - Special Local Regulations; Hurricane Offshore Classic, St. Petersburg, FL.
Code of Federal Regulations, 2012 CFR
2012-07-01
...; Hurricane Offshore Classic, St. Petersburg, FL. 100.728 Section 100.728 Navigation and Navigable Waters... WATERS § 100.728 Special Local Regulations; Hurricane Offshore Classic, St. Petersburg, FL. (a) Regulated..., from 10 a.m. to 6 p.m. EDT. (3) All vessel traffic, not involved in the Hurricane Offshore Classic...
33 CFR 100.728 - Special Local Regulations; Hurricane Offshore Classic, St. Petersburg, FL.
Code of Federal Regulations, 2014 CFR
2014-07-01
...; Hurricane Offshore Classic, St. Petersburg, FL. 100.728 Section 100.728 Navigation and Navigable Waters... WATERS § 100.728 Special Local Regulations; Hurricane Offshore Classic, St. Petersburg, FL. (a) Regulated..., from 10 a.m. to 6 p.m. EDT. (3) All vessel traffic, not involved in the Hurricane Offshore Classic...
ERIC Educational Resources Information Center
MacKendrick, Paul
1979-01-01
Describes several archaeological sites and Roman art works in which to study ancient Roman history, including Lavinium, Paestum, Cosa, Praeneste, the Augustine temples, Sperlonga, the J. Paul Getty Museum, and the cemetery under St. Peter's. (CK)
76 FR 60025 - Product Cancellation Order for Certain Pesticide Registrations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-28
... for Paclobutrazol St. Augustine Grass. 000538-00201 Scotts Turf Manager II.... Paclobutrazol 001270...-264 Sumithrin Powder. 002724-00697 Permanone H and G Insect Permethrin Control. 004822-00531 Raid 1000...
33 CFR 80.750 - Sanibel Island, FL to St. Petersburg, FL.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Sanibel Island, FL to St... SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Gulf Coast § 80.750 Sanibel Island, FL to..., between Captiva Island and Sanibel Island, and lines drawn across Redfish and Captiva Passes parallel to...
Cassel, Jean-Christophe; Cassel, Daniel; Manning, Lilianne
2012-01-01
Over the last half century, neuropsychologists, cognitive psychologists and cognitive neuroscientists interested in human memory have accumulated evidence showing that there is not one general memory function but a variety of memory systems deserving distinct (but for an organism, complementary) functional entities. The first attempts to organize memory systems within a taxonomic construct are often traced back to the French philosopher Maine de Biran (1766–1824), who, in his book first published in 1803, distinguished mechanical memory, sensitive memory and representative memory, without, however, providing any experimental evidence in support of his view. It turns out, however, that what might be regarded as the first elaborated taxonomic proposal is 14 centuries older and is due to Augustine of Hippo (354–430), also named St Augustine, who, in Book 10 of his Confessions, by means of an introspective process that did not aim at organizing memory systems, nevertheless distinguished and commented on sensible memory, intellectual memory, memory of memories, memory of feelings and passion, and memory of forgetting. These memories were envisaged as different and complementary instances. In the current study, after a short biographical synopsis of St Augustine, we provide an outline of the philosopher’s contribution, both in terms of questions and answers, and focus on how this contribution almost perfectly fits with several viewpoints of modern psychology and neuroscience of memory about human memory functions, including the notion that episodic autobiographical memory stores events of our personal history in their what, where and when dimensions, and from there enables our mental time travel. It is not at all meant that St Augustine’s elaboration was the basis for the modern taxonomy, but just that the similarity is striking, and that the architecture of our current viewpoints about memory systems might have preexisted as an outstanding intuition in the philosopher’s mind. PMID:25379224
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-03
...-AA00 Safety Zone; Art Gallery Party St. Pete 2011 Fireworks Display, Tampa Bay, St. Petersburg, FL... temporary safety zone on the waters of Tampa Bay in the vicinity of Spa Beach in St. Petersburg, Florida during the Art Gallery Party St. Pete 2011 Fireworks Display on Friday, November 11, 2011. The safety...
77 FR 419 - Drawbridge Operation Regulation; St. Johns River, Jacksonville, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-05
... Operation Regulation; St. Johns River, Jacksonville, FL AGENCY: Coast Guard, DHS. ACTION: Notice of... bridge across the St. Johns River, mile 24.9, in Jacksonville, Florida. The regulation is set forth in 33... automated railroad bridge over the St. Johns River in Jacksonville, Florida. This temporary deviation will...
St. Augustine 450th Commemoration Commission Act of 2009
Rep. Mica, John L. [R-FL-7
2009-01-13
House - 02/24/2009 Referred to the Subcommittee on Federal Workforce, Post Office, and the District of Columbia. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:
Electrical activity during the 2006 Mount St. Augustine volcanic eruptions
Thomas, Ronald J.; Krehbiel, Paul R.; Rison, William; Edens, H. E.; Aulich, G. D.; McNutt, S.R.; Tytgat, Guy; Clark, E.
2007-01-01
By using a combination of radio frequency time-of-arrival and interferometer measurements, we observed a sequence of lightning and electrical activity during one of Mount St. Augustine's eruptions. The observations indicate that the electrical activity had two modes or phases. First, there was an explosive phase in which the ejecta from the explosion appeared to be highly charged upon exiting the volcano, resulting in numerous apparently disorganized discharges and some simple lightning. The net charge exiting the volcano appears to have been positive. The second phase, which followed the most energetic explosion, produced conventional-type discharges that occurred within plume. Although the plume cloud was undoubtedly charged as a result of the explosion itself, the fact that the lightning onset was delayed and continued after and well downwind of the eruption indicates that in situ charging of some kind was occurring, presumably similar in some respects to that which occurs in normal thunderstorms.
33 CFR 165.721 - Safety Zone: St. Johns River, Jacksonville, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety Zone: St. Johns River... Zone: St. Johns River, Jacksonville, FL. (a) Location. The following area is established as a safety... barges during the storage, preparation, and launching of fireworks in the St. Johns River between the...
NASA Astrophysics Data System (ADS)
Van Stan, J. T.; Stubbins, A.; Reichard, J. S.; Wright, K.; Jenkins, R. B.
2013-12-01
Epiphyte coverage on forest canopies can drastically alter the volume and chemical composition of rainwater reaching soils. Along subtropical and tropical coastlines Tillandisa usneoides L. (Spanish moss), in particular, can envelop urban and natural tree crowns. Several cities actively manage their 'moss' covered forest to enhance aesthetics in the most active tourist areas (e.g., Savannah GA, St. Augustine FL, Charleston SC). Since T. usneoides survives through atmospheric water and solute exchange from specialized trichomes (scales), we hypothesized that T. usneoides water storage dynamics and leachate chemistry may be altered by exposure to this active urban atmosphere. 30 samples of T. usneoides from managed forests around the tourist center of Savannah, Georgia, USA were collected to compare with 30 samples from the pristine maritime live oak (Quercus virginiana Mill.) forests of a nearby undeveloped barrier island (St. Catherines Island, Georgia, USA). Maximum water storage capacities were determined via submersion (for all 60 samples) along with dissolved ion (DI) and organic matter (DOM) concentrations (for 15 samples each) after simulated throughfall generation using milliQ ultrapurified water. Further, DOM quality was evaluated (for 15 samples each) using absorbance and fluorescence spectroscopy (EEMS). Results show significant alterations to water storage dynamics, DI, DOM, and DOM quality metrics under urban atmospheric conditions, suggesting modified C and water cycling in urban forest canopies that may, in turn, influence intrasystem nutrient cycles in urban catchment soils or streams via runoff.
33 CFR 110.73c. - Okeechobee Waterway, St. Lucie River, Stuart, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Okeechobee Waterway, St. Lucie..., St. Lucie River, Stuart, FL. The following is a special anchorage area: Beginning on the Okeechobee Intracoastal Waterway between mile marker 7 and 8 on the St. Lucie River, bounded by a line beginning at 27°12...
33 CFR 80.720 - St. Simons Island, GA to Amelia Island, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false St. Simons Island, GA to Amelia... SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Seventh District § 80.720 St. Simons Island, GA to Amelia Island, FL. (a) A line drawn from St. Simons Light to the northernmost tank on...
33 CFR 165.720 - Safety/Security Zone: St. Johns River, Jacksonville, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety/Security Zone: St. Johns... § 165.720 Safety/Security Zone: St. Johns River, Jacksonville, FL. (a) Location. The water and the land..., within 100 yards of the St. Johns River. (3) All waters within 200 yards of any specified military supply...
78 FR 7670 - Safety Zone; Indian Street Bridge Construction, St. Lucie Canal, Palm City, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-04
... 1625-AA00 Safety Zone; Indian Street Bridge Construction, St. Lucie Canal, Palm City, FL AGENCY: Coast... zone on the St. Lucie Canal, Palm City, Florida to provide for the safety of life and vessels on a... on a narrow waterway. The temporary safety zone encompasses all waters of the St. Lucie Canal in the...
ERIC Educational Resources Information Center
Phi Delta Kappan, 2000
2000-01-01
Recommends leisurely reading for teachers: biographies on St. Augustine and Charles Lindbergh; novels by Edwidge Danticat, Kate Chopin, and Velma Allis; Edward Tufte's three volumes on the visual presentation of information; Jean Vanier's "Becoming Human;" the Harry Potter series, and Michael Tolkin's novel "The Player." (MLH)
Shock Waves and the Origin of Life
1977-01-01
Augustine, St. Thomas Aquinas, Alexander Neckham, Cardinal Damien, Paracelsus, Goethe, Copernicus , Galileo, Harvey, Francis Bacon, Descartes, Hegel and... astronomy and geology. It became thus quite inevitable that the question of how life originated be reopened and examined again in view of the newly
33 CFR 110.73c - Okeechobee Waterway, St. Lucie River, Stuart, FL.
Code of Federal Regulations, 2013 CFR
2013-07-01
... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73c Okeechobee Waterway, St. Lucie River, Stuart, FL. The following is a special anchorage area: Beginning on the Okeechobee...
33 CFR 110.73c - Okeechobee Waterway, St. Lucie River, Stuart, FL.
Code of Federal Regulations, 2012 CFR
2012-07-01
... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73c Okeechobee Waterway, St. Lucie River, Stuart, FL. The following is a special anchorage area: Beginning on the Okeechobee...
33 CFR 110.73c - Okeechobee Waterway, St. Lucie River, Stuart, FL.
Code of Federal Regulations, 2014 CFR
2014-07-01
... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73c Okeechobee Waterway, St. Lucie River, Stuart, FL. The following is a special anchorage area: Beginning on the Okeechobee...
33 CFR 110.73c. - Okeechobee Waterway, St. Lucie River, Stuart, FL.
Code of Federal Regulations, 2011 CFR
2011-07-01
... HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73c. Okeechobee Waterway, St. Lucie River, Stuart, FL. The following is a special anchorage area: Beginning on the Okeechobee...
The World of Instruction: Undertaking the Impossible
ERIC Educational Resources Information Center
Laverty, Megan J.
2014-01-01
Throughout history, philosophers have reflected on educational questions. Some of their ideas emerged in defense of, or opposition to, skepticism about the possibility of formal teaching and learning. These philosophers include Plato, Augustine, St Thomas Aquinas, Søren Kierkegaard, Martin Heidegger, and Ludwig Wittgenstein. Together, they…
DERMAL TRANSFER EFFICIENCY OF PESTICIDES FROM TURF GRASS TO DRY AND WETTED PALMS
This report presents results of a study to determine the transfer of three pesticides commonly used in residential lawn care from turf grass to human skin. Formulation of the insecticides chlorpyrifos and cyfluthrin and the fungicide chlorothalonil were applied to St. Augustin...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-12
... Zone; Festival of States 2012 Night Parade Fireworks Display, Tampa Bay, St. Petersburg, FL AGENCY... safety zone on the waters of Tampa Bay in St. Petersburg, Florida during Festival of States 2012 Night... Thursday, March 22, 2012, the Festival of States 2012 Night Parade Fireworks Display is scheduled to take...
A Moral Framework for War in the 21st Century
2009-03-26
there to see his world descend into darkness as barbarians and pagan hordes began to dismantle the only civilization he had ever known. Augustine was...its short history. He was well aware of the persecution that took place throughout Rome prior to Constantine becoming a Christian and adopting
USDA-ARS?s Scientific Manuscript database
We evaluated the oviposition response of Aedes albopictus to six organic infusions. Laboratory and field placed ovitraps baited with water oak (Quercus nigra L.), longleaf pine (Pinus palustris P. Mill) and St. Augustine grass (Stenotaphrum secundatum (Walt.) Kuntze), as well as two-species mixture...
ERIC Educational Resources Information Center
Child & Youth Services, 2007
2007-01-01
In this chapter I describe the micro "risk society" of Limerick City and St. Augustine's Youth Encounter Project in terms of the social and cultural background of the interviewees, their perceived family and community identity, and their wider socialisation influences. The project is situated down one of the notorious Limerick lanes made…
2016-07-01
period 1941 to 1957 resulted in the construction of a north sand-trap groin structure approxi- mately 1,880 ft in length and a 3,695 ft long southern...jetty structure . The inlet channel and associated structures are maintained by SAJ. The project includes an outer channel authorized to -16 ft mean...erosion, several homes had to be temporarily vacated for major repairs, and several structures were granted permits to construct temporary sea walls
1992-02-01
MKK) Daytona Beach, FL (DAB) Boise, ID (BOI) Fort Lauderdale, FL (FLL) Idaho Falls Fanning Field, ID (IDA) Fort Lauderdale Executive, FL (FXE... Lewiston , ID (LWS) Fort Myers Page Field, FL (FMY) Pocatello, ID (PIH) Fort Myers Regional, FL (RSW) Twin Falls, ID (TWF) Fort Pierce, FL (FPR) Alton St... Idaho (SUN) 6. Marion Williamson County, Illinois (MWA) 7. Waukegan, Illinois (UGN) 8. Topeka-Phillip Ballard, Kansas (TOP) 9. Owensboro-Daviees County
Manning, Liliann; Cassel, Daniel; Cassel, Jean-Christophe
2013-01-01
Reconstructing the past and anticipating the future, i.e., the ability of travelling in mental time, is thought to be at the heart of consciousness and, by the same token, at the center of human cognition. This extraordinary mental activity is possible thanks to the ability of being aware of ‘subjective time’. In the present study, we attempt to trace back the first recorded reflections on the relations between time and memory, to the end of the fourth century’s work, the Confessions, by the theologian and philosopher, St. Augustine. We concentrate on Book 11, where he extensively developed a series of articulated and detailed observations on memory and time. On the bases of selected paragraphs, we endeavor to highlight some concepts that may be considered as the product of the first or, at least, very early reflections related to our current notions of subjective time in mental time travel. We also draw a fundamental difference inherent to the frameworks within which the questions were raised. The contribution of St. Augustine on time and memory remains significant, notwithstanding the 16 centuries elapsed since it was made, likely because of the universality of its contents. PMID:25379236
Feminism across the Disciplines.
ERIC Educational Resources Information Center
Russell-Robinson, Joyce
A course taught at St. Augustine's College uses "A Voice from the South" (1893) by Anna J. Cooper (a collection of essays representing women as being bold, in-charge decision makers) as an example of how "Feminism across the Disciplines" is expressed. These essays, as well as works of a number of other writers, can be used in…
Spanish Quarter Museum Pre-Tour Packet for Teachers.
ERIC Educational Resources Information Center
VanVleet, Susan
This guide provides teachers with background information and teaching activities to prepare students for a visit to the Spanish Quarter Museum in St. Augustine, Florida. It is designed to familiarize students with some of the concepts and words they will encounter in the open-air living history museum where interpreters in period clothing re-live…
The Model Technology School: Toward Literacy through Technology. Technology.
ERIC Educational Resources Information Center
Schneider, Raymond J.
This paper describes one Florida school's experience with the Model Technology Schools (MTS) pilot program, and proposes a poetry curriculum for K-12 education that incorporates laserdisc technology for student presentations. Webster Elementary School in St. Augustine was the smallest of five schools chosen for the MTS program to demonstrate the…
Meeting the Needs of Nontraditional Students: Retention and Transfer Studies.
ERIC Educational Resources Information Center
Kraemer, Barbara
St. Augustine College (SAC), in North Carolina, has undertaken four studies to gather data on factors related to student persistence, transfer, and withdrawal from the college. In the first study, graduating students from June 1990 to December 1992 were surveyed to determine influences on their decisions to transfer to a university. Three major…
75 FR 4839 - Endangered and Threatened Wildlife and Plants; Permit, St. Lucie County, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-29
...] Endangered and Threatened Wildlife and Plants; Permit, St. Lucie County, FL AGENCY: Fish and Wildlife Service...-jay) breeding, feeding, and sheltering habitat incidental to lot preparation for the construction of a...)) of Florida scrub-jay breeding, feeding and sheltering habitat incidental to land preparation for...
50 CFR 622.9 - Vessel monitoring systems (VMSs).
Code of Federal Regulations, 2010 CFR
2010-10-01
..., St. Petersburg, FL 33701; phone: 800-758-4833. An operating VMS includes an operating mobile... board when on a trip in the South Atlantic. An operating VMS includes an operating mobile transmitting... Region, 263 13th Avenue South, St. Petersburg, FL 33701; phone: 800-758-4833; and (2) Submit to NMFS...
Factors Influencing Beginning Teacher Retention in the Diocese of St. Augustine Catholic Schools
ERIC Educational Resources Information Center
Bronsard, Patricia
2012-01-01
Researchers explored the problem of teacher retention, especially among beginning teachers, and noted a lack of consensus on why teachers leave teaching and how to retain the teachers. Private school studies include Catholic school data, but few researchers isolated the data or used data-gathering instruments to examine Catholic school issues,…
U.S. EPA, Pesticide Product Label, SPEED ZONE ST.AUGUSTINE FORMULA BROADLEAF HERBICIDE, 11/23/2009
2011-04-14
... 9°nt?i~:~rf.j~~~in~1?,9.i~a.niQg;~h~8?ntcii:q~~:~~f~r~;:~h~J.,d,s~'9.~al::i;~~~~ e,'t~sp ... Wind Speed Do not apply at wind speeds greater than 15 ...
1996-03-01
Barataria Basin. Byrd (1976) examined the nutritional and caloric value of this brackish water mollusk in order to determine its relative importance to... Yucatan ) received 149 settlers in the period 1733-1735; the future San Antonio, Texas, received 56 Islefios in 1730; St. Augustine received 707
Children and Youth: The Evolution of At Risk to "High Promise" Youth
ERIC Educational Resources Information Center
Child & Youth Services, 2007
2007-01-01
It is impossible to make global generalisations about children and youth from a phenomenological inquiry into the experiences of such a limited number of participants in just one city, Limerick, Ireland, and one case, St. Augustine's. The goal of phenomenological research is, however, not to seek generalisations but to expose the individual case,…
The Use of an Information Brokering Tool in an Electronic Museum Environment.
ERIC Educational Resources Information Center
Zimmermann, Andreas; Lorenz, Andreas; Specht, Marcus
When art and technology meet, a huge information flow has to be managed. The LISTEN project conducted by the Fraunhofer Institut in St. Augustin (Germany) augments every day environments with audio information. In order to distribute and administer this information in an efficient way, the Institute decided to employ an information brokering tool…
Lock No. 1 St. Lucie Canal. Upper gate structure, masonry ...
Lock No. 1- St. Lucie Canal. Upper gate structure, masonry plan- masonry elevations. - St. Lucie Canal, St. Lucie Lock No. 1, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
Cheng, Yky; Leung, T Y; Lao, Tth; Chan, Y M; Sahota, D S
2016-09-01
To assess the impact of adopting the INTERGROWTH-21(st) biometry standards in a Chinese population. Retrospective cohort study. A teaching hospital in Hong Kong. A total of 10 527 Chinese women with a singleton pregnancy having a second- or third-trimester fetal anomaly or growth scan between January 2009 and June 2014. Z-scores were derived for fetal abdominal circumference (AC), head circumference (HC), and femur length (FL) using the INTERGROWTH-21(st) and Chinese biometry standards. Pregnancies with aneuploidy, structural or skeletal abnormalities, or that developed pre-eclampsia were excluded. Z-scores were stratified as <2.5th, <5th, <10th, >90th, >95th, or >97.5th percentile. Birthweight centile, adjusted for gestation and gender, was categorised as ≤3rd, 3rd to ≤5th, 5th to ≤10th, and >10th. Pairwise comparison and the McNemar test were performed to assess biometry Z-score differences and concordance between the INTERGROWTH-21(st) and Chinese standards. The sensitivity of both the local and INTERGROWTH-21(st) AC standards to identify pregnancies that were small-for-gestational-age (SGA) was assessed. INTERGROWTH-21(st) AC, HC, and FL Z-scores were significantly lower than those obtained using our local reference for AC, HC, and FL (P < 0.0001 for all). The proportion of fetuses with biometry in the <2.5th, <5th, <10th, >90th, >95th, or >97.5th percentiles was statistically significant (P < 0.01 for all). A total of 1224 (15.5%) of the scans at 18-22 weeks of gestation had AC, HC, or FL below the 3rd percentile of the INTERGROWTH-21(st) standard. Adopting the INTERGROWTH-21(st) standard would lead to a significant number of fetuses being at risk of misdiagnosis for small fetal size, particularly when using HC and FL measures. INTERGROWTH-21(st) biometry assessment in Chinese leads to fetuses being at risk of misdiagnosis of small fetal size. © 2016 Royal College of Obstetricians and Gynaecologists.
75 FR 47899 - Bayside Savings Bank, Port St. Joe, FL; Notice of Appointment of Receiver
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-09
... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Bayside Savings Bank, Port St. Joe, FL... section 5(d)(2) of the Home Owners' Loan Act, the Office of Thrift Supervision has duly appointed the..., (OTS No. 17957) on July 30, 2010. Dated: August 2, 2010. By the Office of Thrift Supervision. Sandra E...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-23
...-AA87 Security Zones; 2012 RNC Bridge Security Zones, Captain of the Port St. Petersburg Zone, Tampa, FL... temporary security zones around certain bridges on the waters of Pinellas County and Tampa Bay, Florida..., or mooring on waters within 50 yards of the designated bridges during the times that the security...
2003-01-01
Groundcover on base consists primarily of Bermuda grass ( Cynodon dactylon), centipede grass (Eremochloa ophiluroides), and St. Augustine grass...notification to allow adequate lime fori eview. COASTAL PROGRAM COMPLIANCE (Coastal ari • activities only) : ( ) The activity has been reviewed and
ERIC Educational Resources Information Center
Thompson, R.W.
An international conference on creole languages and educational development was held at the University of the West Indies, St. Augustine, Trinidad, from July 24-28, 1972. It was attended by scholars from Africa, Australia, Hawaii, the Caribbean region, the United Kingdom, the United States, and France. The papers presented were descriptions of a…
ERIC Educational Resources Information Center
Clarke, Reginald
2002-01-01
Explains the need for attention to library environment in terms of conservation, disaster planning, and external environmental factors. Discusses measures adopted at the University of the West Indies Trinidad related to operation and maintenance of buildings and physical plant, describes a workplace evaluation project, and examines factors…
Simultaneity, relativity and conventionality
NASA Astrophysics Data System (ADS)
Janis, Allen I.
2008-01-01
The view of simultaneity presented by Max Jammer is almost breathtaking, encompassing, as the book's subtitle suggests, the period from antiquity to the 21st century. Many interesting things are to be found along the way. For example, what Jammer (p. 49) says "may well be regarded as probably the earliest recorded example of an operational definition of distant simultaneity" is due to St. Augustine (in his Confessions, written in 397 A.D.; for a modern translation, see Augustine, 2006). He was arguing against astrology by presenting the story of two women, one rich and one poor, who gave birth simultaneously. Although the two children thus had precisely the same horoscopes, their lives followed quite different courses. And how was it determined that the births were simultaneous? A messenger went from each birth site to the other, leaving the instant the child was born (and, presumably, traveling with equal speeds). Since the messengers met at the midpoint between the locations of the two births, the births must have been simultaneous. This is, of course, quite analogous to Albert Einstein's definition of simultaneity (given more than 1500 years later), which will be discussed in Section 2.1.
Bacterioplankton Dynamics in Pensacola Bay, FL, USA: Role of Phytoplankton and Detrital Carbon Sources (Abstract). To be presented at the16th Biennial Conference of the Estuarine Research Foundation, ERF 2001: An Estuarine Odyssey, 4-8 November 2001, St. Pete Beach, FL. 1 p. (ER...
Effects of Stress and Relaxation on Time Perception
2003-01-01
were included in the writings of such renowned philosophers as St. Augustine, Rene Descartes, Thomas Hobbes, John Lock, and Immanuel Kant (Nichols...progressive muscle relaxation exercise, or control (n = 39) - listening to a biography on tape. Multiple measures of time production, time estimation...39) � listening to a biography on tape. Multiple measures of time production, time estimation, perceived rate, and attention to time domains (past
The Situation of Students in Sub-Saharan Africa: A Case Study of St Augustine University of Tanzania
ERIC Educational Resources Information Center
Muller, Bernadette; Haller, Max
2012-01-01
It is widely recognised that higher education is crucial for socio-economic growth in developing countries. Sub-Saharan Africa (SSA) is lagging behind in this regard in spite of a strong expansion of universities in the last decades. However, this growth may have led to a deterioration of the quality of higher education. There is no dearth of…
Endothelial marker-expressing stromal cells are critical for kidney formation.
Mukherjee, Elina; Maringer, Katherine; Papke, Emily; Bushnell, Daniel; Schaefer, Caitlin; Kramann, Rafael; Ho, Jacqueline; Humphreys, Benjamin D; Bates, Carlton; Sims-Lucas, Sunder
2017-09-01
Kidneys are highly vascularized and contain many distinct vascular beds. However, the origins of renal endothelial cells and roles of the developing endothelia in the formation of the kidney are unclear. We have shown that the Foxd1-positive renal stroma gives rise to endothelial marker-expressing progenitors that are incorporated within a subset of peritubular capillaries; however, the significance of these cells is unclear. The purpose of this study was to determine whether deletion of Flk1 in the Foxd1 stroma was important for renal development. To that end, we conditionally deleted Flk1 (critical for endothelial cell development) in the renal stroma by breeding-floxed Flk1 mice ( Flk1 fl/fl ) with Foxd1cre mice to generate Foxd1cre; Flk1 fl/fl ( Flk1 ST-/- ) mice. We then performed FACsorting, histological, morphometric, and metabolic analyses of Flk1 ST-/- vs. control mice. We confirmed decreased expression of endothelial markers in the renal stroma of Flk1 ST-/- kidneys via flow sorting and immunostaining, and upon interrogation of embryonic and postnatal Flk1 ST-/- mice, we found they had dilated peritubular capillaries. Three-dimensional reconstructions showed reduced ureteric branching and fewer nephrons in developing Flk1 ST-/- kidneys vs. Juvenile Flk1 ST-/- kidneys displayed renal papillary hypoplasia and a paucity of collecting ducts. Twenty-four-hour urine collections revealed that postnatal Flk1 ST-/- mice had urinary-concentrating defects. Thus, while lineage-tracing revealed that the renal cortical stroma gave rise to a small subset of endothelial progenitors, these Flk1-expressing stromal cells are critical for patterning the peritubular capillaries. Also, loss of Flk1 in the renal stroma leads to nonautonomous-patterning defects in ureteric lineages. Copyright © 2017 the American Physiological Society.
Selenium deficiency in cattle associated with Heinz bodies and anemia.
Morris, J G; Cripe, W S; Chapman, H L; Walker, D F; Armstrong, J B; Alexander, J D; Miranda, R; Sanchez, A; Sanchez, B; Blair-West, J R
1984-02-03
Cattle grazing St. Augustine grass growing on peaty muck soils in the Florida Everglades developed anemia associated with the presence of Heinz bodies and suboptimal concentrations of selenium in blood. Selenium supplementation corrected the anemia, prevented Heinz body formation, increased the body weight of cows and calves, and elevated blood selenium. This may be the first recorded example of widespread anemia in a population due to selenium deficiency.
NASA Astrophysics Data System (ADS)
Winson, A.; Kinvig, H.; Gottsmann, J.; Partington, E.; Geyer, A.
2008-10-01
We present an analysis of volcanic threat of Nisyros island (Greece) based on a catalogue of questions compiled for the USGS National Volcano Early Warning System (NVEWS). We find that the score puts Nisyros in the league of volcanoes posing a very high threat. US volcanoes with a comparable threat level include Mt. St. Helens, Augustine and the Long Valley caldera.
Short Term Cyber Attacks with Long Term Effects and Degradation of Supply Chain Capability
2016-09-01
Artificial Intelligence Research Society Conference, 271–275, St. Augustine: Florida. Goetschalckx, Marc. 2011. Supply Chain Engineering. New York: Springer...term risks in a network supply chain to establish the existence of black swan events. 14. SUBJECT TERMS cybersecurity , supply chain risk...Mission, and Information System View (NIST SP 800–39) .....50 6. Cybersecurity Instruction for the DOD (DODI 8500.01) .........51 7. Risk Management
ERIC Educational Resources Information Center
McElwee, Niall
2007-01-01
Mark Twain once famously quipped, "I never let schooling get in the way of my education." Paul Simon, the American folk singer, begins one of his songs "When I think back on all the crap I learned at high school, it's a wonder I can hardly think at all." These men could just have easily been discussing schooling in Ireland, for…
33 CFR 80.727 - Cape Canaveral, FL to Miami Beach, FL.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 80°09.7′ W.) drawn across St. Lucie Inlet. (e) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet...
33 CFR 80.727 - Cape Canaveral, FL to Miami Beach, FL.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 80°09.7′ W.) drawn across St. Lucie Inlet. (e) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet...
33 CFR 80.727 - Cape Canaveral, FL to Miami Beach, FL.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 80°09.7′ W.) drawn across St. Lucie Inlet. (e) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet...
33 CFR 80.727 - Cape Canaveral, FL to Miami Beach, FL.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 80°09.7′ W.) drawn across St. Lucie Inlet. (e) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet...
33 CFR 80.727 - Cape Canaveral, FL to Miami Beach, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 80°09.7′ W.) drawn across St. Lucie Inlet. (e) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet...
Castro-González, María Isabel; Carrillo-Domínguez, Silvia
2015-09-01
the regular consumption of fish brings benefits to health due to its content of n-3 fatty acids, but cooking enhances or damages the concentration of fatty acids (FA) since they are susceptible to oxidation by temperatures and cooking times. to analyze the effect of six cooking techniques on total lipids (TL) and (FA) content in marlin and hake and select which one helps the best conservation of health beneficial FA. fillets were subjected to different cooking techniques: steam (ST), foiled-aluminum-paper (FAP), foiled- banana-leaf (FBL), gas-oven (GO), microwave-oven (MO) and fried-lightly (FL). FA were identified by gas chromatography/FID. Marlin: FL increased the concentration of TL and MO decreased it. Statistically, PUFA, SFA and EPA + DHA increased with FAP, MUFA decreased with FBL and increased in FL. Hake: FL increased concentration in all groups of FA while ST decreased it. SFA values and index of atherogenicity (IA), thrombogenicity (IT), peroxidisability and hipocolesterolemic/ hipercolesterolemic fatty acid ratio (HH) found, suggested that hake is a fish with greater health benefits, regardless of the technique you employ. By its EPA + DHA content, marlin seems to be an excellent choice if cooked FAP. FL technique in both species decreased the IA, IT and significantly increased the HH; however n3/n6 ratio decreased. ST seems to be the least desirable cooking technique for both species. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
Garcia, Vhon Oliver S; Ivy, Catherine; Fu, Jinzhong
2017-11-01
Amphibians are often considered excellent environmental indicator species. Natural and man-made landscape features are known to form effective genetic barriers to amphibian populations; however, amphibians with different characteristics may have different species-landscape interaction patterns. We conducted a comparative landscape genetic analysis of two closely related syntopic frog species from central China, Pelophylax nigromaculatus ( PN ) and Fejervarya limnocharis ( FL ). These two species differ in several key life history traits; PN has a larger body size and larger clutch size, and reaches sexual maturity later than FL . Microsatellite DNA data were collected and analyzed using conventional ( F ST , isolation by distance (IBD), AMOVA) and recently developed (Bayesian assignment test, isolation by resistance) landscape genetic methods. As predicted, a higher level of population structure in FL ( F ST ' = 0.401) than in PN ( F ST ' = 0.354) was detected, in addition to FL displaying strong IBD patterns ( r = .861) unlike PN ( r = .073). A general north-south break in FL populations was detected, consistent with the IBD pattern, while PN exhibited clustering of northern- and southern-most populations, suggestive of altered dispersal patterns. Species-specific resistant landscape features were also identified, with roads and land cover the main cause of resistance to FL , and elevation the main influence on PN . These different species-landscape interactions can be explained mostly by their life history traits, revealing that closely related and ecologically similar species have different responses to the same landscape features. Comparative landscape genetic studies are important in detecting such differences and refining generalizations about amphibians in monitoring environmental changes.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-17
... 1625-AA08 Special Local Regulations; Jacksonville Dragon Boat Festival; St. Johns River; Jacksonville... Special Local Regulation on the waters of the St. Johns River in Jacksonville, Florida during the... portion of the St. Johns River. Non-participant persons and vessels will be prohibited from entering or...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-06
... Exclusive Economic Zone of St. Thomas/St. John AGENCY: National Marine Fisheries Service (NMFS), National... economic zone (EEZ) of St. Thomas/St. John. The purpose of this NOI is to inform the public of upcoming..., NMFS, 263 13th Avenue South, St. Petersburg, FL 33701, or to the Caribbean Fishery Management Council...
ENVIRONMENTAL SCIENCES IN THE 21ST CENTURY: PARADIGMS, OPPORTUNITIES, AND CHALLENGES
In: Environmental Sciences in the 21st Century: Paradigms, Opportunities, and Challenges: Abstract Book: SETAC 21st Annual Meeting, 12-16 November 2000, Nashville, TN.. Society of Environmental Toxicology and Chemistry, Pensacola, FL. Pp. p. 180.
Bioavailability and rates...
Uncontrolled pneumonia in a 49-year-old white man.
Taghizadeh, Farnoush; Raghuwanshi M, Raghuraj S
2014-01-01
A 49-year-old white man. Shortness of breath, fever, and ongoing unintended weight loss. The patient had arrived at the emergency department of a hospital in St. Augustine, Florida with coughing and progressive shortness of breath. He reported that he had been experiencing these symptoms for the past 6 weeks. He was examined by his primary physician, who had prescribed him a course of antibiotics and treated him on an outpatient basis. The patient reported no improvement in his symptoms at present, despite the antibiotics. He mentioned that he had traveled to St. Augustine, Florida approximately 10 days previously. Medical personnel in the emergency department subsequently performed a chest x-ray on the patient, as well as computed tomography (CT) scanning of his lymphadenopathy. MEDICAL AND FAMILY HISTORY: Positive for hypertension, diabetes mellitus, and osteoporosis. He reported that he has chewed 2 packs of chewing tobacco per day for the past 30 years, occasionally drinks alcohol, and is a nonsmoker with no known allergies. Noncontributory. Noncontributory. The patient exhibited mild respiratory distress; however, he was awake, alert, and oriented, with a temperature of 37.3°C. He also exhibited poor respiratory effort with diffuse expiratory rhonchi. His heart rate and heart rhythm were regular, with no murmurs, gallops, or rubs. His bowel sounds were positive; he exhibited no organomegaly and no cyanosis, clubbing, or edema of his extremities.
CRANE WINCH MECHANISM, UPPER LEVEL OF HYDROELECTRIC POWER HOUSE ...
CRANE WINCH MECHANISM, UPPER LEVEL OF HYDROELECTRIC POWER HOUSE - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
ELECTRICAL SWITCHBOARD IN UPPER LEVEL OF HYDROELECTRIC POWER HOUSE ...
ELECTRICAL SWITCHBOARD IN UPPER LEVEL OF HYDROELECTRIC POWER HOUSE - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
75 FR 79293 - Amendment and Revocation of Class E Airspace; Vero Beach, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-20
... geographic coordinates of the St. Lucie County International Airport to aid in the navigation of our National... the National Aeronautical Navigation Services to update the geographic coordinates of the St. Lucie.... Also, this action will update the geographic coordinates of the St. Lucie County International Airport...
Oblique view of southwest and southeast side of northwest machinery ...
Oblique view of southwest and southeast side of northwest machinery house and hydro-electric power house, concrete pylon at upstream entrance to lock in foreground, view towards north - St. Lucie Canal, St. Lucie Lock No. 1, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
VIEW OF SOUTHEAST SIDE OF HYDROELECTRIC POWER HOUSE, VIEW TOWARDS ...
VIEW OF SOUTHEAST SIDE OF HYDROELECTRIC POWER HOUSE, VIEW TOWARDS NORTHWEST - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
PLANAR VIEW OF NORTHWEST SIDE OF HYDROELECTRIC POWER HOUSE, VIEW ...
PLANAR VIEW OF NORTHWEST SIDE OF HYDROELECTRIC POWER HOUSE, VIEW TOWARDS SOUTHEAST - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
HANDMADE WOODEN RACK FOR TOOL STORE, LOWER LEVEL OF HYDROELECTRIC ...
HANDMADE WOODEN RACK FOR TOOL STORE, LOWER LEVEL OF HYDROELECTRIC POWER HOUSE - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
HARNESS END OF ELECTRIC TURBINE IN LOWER LEVEL OF HYDROELECTRIC ...
HARNESS END OF ELECTRIC TURBINE IN LOWER LEVEL OF HYDROELECTRIC POWER HOUSE - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
DETAIL INTERIOR VIEW OF CONTROL PANEL IN CONTROL STATION, VIEW ...
DETAIL INTERIOR VIEW OF CONTROL PANEL IN CONTROL STATION, VIEW TOWARDS WEST - St. Lucie Canal, Lock No. 1, Control Station, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
75 FR 23608 - Final Flood Elevation Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-04
... Jewett +88 Town of White Springs Street. Approximately 600 feet +109 upstream of 1st Street. Timber Lake... Hamilton Avenue, Jennings, FL 32053 Town of White Springs Maps are available for inspection at the Town Hall, 10363 Bridge Street, White Springs, FL 32096 Unincorporated Areas of Hamilton County Maps are...
1997-03-01
characteristic musk odor [7]. Molecular shape is important in circular dichroism and chirality. Enantiomers, if viewed in isolation, have identical all...simply a function of the length of the elon - gated structure). We can introduce V/S as an index of molecular shape by using computed molecular
2015-02-08
dinotefuran has successful con- trolled Culex and Aedes spp. in similar field sites in Morocco [22]. However, this if the first report of the use of...et al. Control of Aedes abopttus with attractive toxic sugar baits (A TSB) and potential Impact on non target organisms In St. Augustine, Florida...of Anopheles sergenti and Aedes CO!Pk.JS populations following presentation of attractive toxic (splnosad) sugar bait stations In an oasis. J Am
2012-07-01
Beaches + Anastasia cu y d/ yr Table 1. Measured Ebb-delta Volume of St. Augustine Inlet, Florida at the 30ft contour (Legault et al. 2012...along Anastasia State Park). The permeability of the terminal groins (between 0% and 100%) were estimated based on visual inspection of sand...lft) Percent volume change for the three reaches and the ebb-tidal delta are shown in Figure 15 for all modeled alternatives. Anastasia State
Men, Salt, Cattle and Battle: The Civil War in Florida (November 1860-July 1865)
1992-06-01
M. Yard, captured British schooner Mabel east of Jacksonville, Florida. (CWNC: pg 1-37) 17 U.S.S. Connecticut, Commander Maxwell Woodhull, captured...reported Confederate pickets at Nine-Mile Hammock, on the Orange Springs Road, and at a point four miles from Palatka on the Rice Creek Road; and a...Lieutenant Marshall N. Rice , USA, Thirty-fifth U.S. Colored Troops, USA, en route from Jacksonville to St. Augustine, Florida, captured by three Confederate
OBLIQUE VIEW OF NORTHEAST AND SOUTHEAST SIDES OF HYDROELECTRIC POWER ...
OBLIQUE VIEW OF NORTHEAST AND SOUTHEAST SIDES OF HYDROELECTRIC POWER HOUSE, VIEW TOWARDS WEST - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
DETAIL INTERIOR VIEW OF ELECTRIC GENERATOR ON UPPER LEVEL ON ...
DETAIL INTERIOR VIEW OF ELECTRIC GENERATOR ON UPPER LEVEL ON HYDROELECTRIC POWER HOUSE - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
Stirnemann, J J; Fries, N; Bessis, R; Fontanges, M; Mangione, R; Salomon, L J
2017-04-01
To assess potential differences in fetal size between the French population and the international population from the INTERGROWTH-21 st (IG-21 st ) Project and to measure the impact of switching to the IG-21 st reference standards for fetal size. This was a nationwide cross-sectional study of fetal ultrasound biometry. Low-risk singleton pregnancies were recruited prospectively within the network of the national French College of Fetal Ultrasound, CFEF, over a 6-week period. Further selection was performed based on the criteria of the IG-21 st Project in order to obtain a comparable population. Head circumference (HC) was used as the main fat-free skeletal measure of growth for comparison of French fetal size with that of the IG-21 st population. The impact of switching to the IG-21 st fetal growth standards was quantified by comparing Z-scores calculated using the IG-21 st standards with those calculated using locally derived reference ranges for HC, abdominal circumference (AC) and femur length (FL). Following selection, 4858 cases were analyzed. The distribution of HC demonstrated clear similarity between our French population and the IG-21 st population: our observed centile curves closely matched those of IG-21 st and the Z-scores were close to 0 across gestational age. The IG-21 st standards performed as well as did locally derived charts in terms of screening for small-for-gestational age by AC, while they identified significantly fewer small FL values than were expected and than did the locally derived charts. Under strict selection criteria, fetal size in France is similar to that of the international population used in the IG-21 st Project. The discrepancies in FL are unlikely to impact on prenatal management. Therefore, switching from locally derived reference ranges to the IG-21 st standards appears to be a safe option. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd.
76 FR 36482 - Proposed Flood Elevation Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-22
... Marian. WPA Canal Tributary 1 Approximately 1,612 None + 71 City of St. Cloud, feet upstream of the... Kite Avenue. WPA Canal Tributary 1-1 At the WPA Canal None + 75 City of St. Cloud, Tributary 1..., FL 34741. City of St. Cloud Maps are available for inspection at City Hall, Public Works Department...
A history of erotic philosophy.
Soble, Alan
2009-01-01
This essay historically explores philosophical views about the nature and significance of human sexuality, starting with the Ancient Greeks and ending with late 20th-century Western philosophy. Important figures from the history of philosophy (and theology) discussed include Sappho, Plato, Aristotle, St. Augustine, St. Jerome, the Pelagians, St. Thomas Aquinas, Michel de Montaigne, Rene Descartes, Thomas Hobbes, David Hume, Immanuel Kant, Søren Kierkegaard, Arthur Schopenhauer, Jeremy Bentham, John Stuart Mill, Karl Marx, Friedrich Engels, Sigmund Freud, Jean-Paul Sartre, Simone de Beauvoir, Wilhelm Reich, and Herbert Marcuse. Contemporary philosophers whose recent work is discussed include Michel Foucault, Thomas Nagel, Roger Scruton, Karol Wojtyla (Pope John Paul II), Catharine MacKinnon, Richard Posner, and John Finnis. To show the unity of the humanities, the writings of various literary figures are incorporated into this history, including Mark Twain, Arthur Miller, James Thurber, E. B. White, Iris Murdoch, and Philip Roth.
49 CFR Appendix A to Part 1580 - High Threat Urban Areas (HTUAs)
Code of Federal Regulations, 2010 CFR
2010-10-01
... the border of the combined area Anaheim, CA; Santa Ana, CA. Bay Area Berkeley, Daly City, Fremont... Jacksonville and a 10-mile buffer extending from the city border Jacksonville, FL. Miami Area Hialeah, Miami... and a 10-mile buffer extending from the city border Orlando, FL. Tampa Area * Clearwater, St...
49 CFR Appendix A to Part 1580 - High Threat Urban Areas (HTUAs)
Code of Federal Regulations, 2011 CFR
2011-10-01
... the border of the combined area Anaheim, CA; Santa Ana, CA. Bay Area Berkeley, Daly City, Fremont... Jacksonville and a 10-mile buffer extending from the city border Jacksonville, FL. Miami Area Hialeah, Miami... and a 10-mile buffer extending from the city border Orlando, FL. Tampa Area * Clearwater, St...
77 FR 38772 - Atlantic Highly Migratory Species; Electronic Dealer Reporting System Workshop
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-29
... Orange, Florida; Seminole, Florida; Fort Lauderdale, Florida; and Marathon, Florida Keys. See... 2230 NW 21st Avenue, Library. Fort Lauderdale, FL 33311. September 5, 2012 6:30-9:30 p.m Marathon Government 2798 Overseas Highway, Center. Milemarker 48.5, EOC BOCC Meeting Room, 2nd Floor, Marathon, FL...
Phytoplankton, zooplankton and water quality parameters were monitored monthly along a 5-station transect in Escambia Bay (Pensacola, FL) from fall 1999 to fall 2000. To provide insight into nutrient processing in Escambia Bay and effects of grazers on phytoplankton community st...
LOW DOSE PESTICIDE EXPOSURE AND ALTERED REPRODUCTIVE SYSTEM DEVELOPMENT IN REPTILES
In: Environmental Sciences in the 21st Century: Paradigms, Opportunities, and Challenges: Abstract Book: SETAC 21st Annual Meeting, 12-16 November 2000, Nashville, TN. Society of Environmental Toxicology and Chemistry, Pensacola, FL. Pp. 99.
INTER-SPECIES STEROID RECEPTOR EXTRAPOLATION STUDIES FOR ENDOCRINE DISRUPTING CHEMICALS
In: Environmental Sciences in the 21st Century: Paradigms, Opportunities, and Challenges: Abstract Book: SETAC 21st Annual Meeting, 12-16 November 2000, Nashville, TN. Society of Environmental Toxicology and Chemistry, Pensacola, FL. Pp. 117-118.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-21
...-AA00 Safety Zone; The Florida Orchestra Pops in the Park Fireworks Display, Tampa Bay, St. Petersburg... temporary safety zone on the waters of Tampa Bay in the vicinity of Spa Beach in St. Petersburg, Florida..., anchoring in, or remaining within the safety zone unless authorized by the Captain of the Port St...
A potential approach for low flow selection in water resource supply and management
NASA Astrophysics Data System (ADS)
Ouyang, Ying
2012-08-01
SummaryLow flow selections are essential to water resource management, water supply planning, and watershed ecosystem restoration. In this study, a new approach, namely the frequent-low (FL) approach (or frequent-low index), was developed based on the minimum frequent-low flow or level used in minimum flows and/or levels program in northeast Florida, USA. This FL approach was then compared to the conventional 7Q10 approach for low flow selections prior to its applications, using the USGS flow data from the freshwater environment (Big Sunflower River, Mississippi) as well as from the estuarine environment (St. Johns River, Florida). Unlike the FL approach that is associated with the biological and ecological impacts, the 7Q10 approach could lead to the selections of extremely low flows (e.g., near-zero flows) that may hinder its use for establishing criteria to prevent streams from significant harm to biological and ecological communities. Additionally, the 7Q10 approach could not be used when the period of data records is less than 10 years by definition while this may not the case for the FL approach. Results from both approaches showed that the low flows from the Big Sunflower River and the St. Johns River decreased as time elapsed, demonstrating that these two rivers have become drier during the last several decades with a potential of salted water intrusion to the St. Johns River. Results from the FL approach further revealed that the recurrence probability of low flow increased while the recurrence interval of low flow decreased as time elapsed in both rivers, indicating that low flows occurred more frequent in these rivers as time elapsed. This report suggests that the FL approach, developed in this study, is a useful alternative for low flow selections in addition to the 7Q10 approach.
Learning to Read with Augustine of Hippo
ERIC Educational Resources Information Center
Rine, C. Rebecca
2007-01-01
The confessions of Augustine of Hippo can be read as a lesson in reading, one in which Augustine teaches by example as well as precept. Throughout this work, the relationship between faith and reading is clearly on Augustine's mind, as is his desire to teach others what he has learned. As we consider our own approaches to the confluence of faith,…
Ito, Yukako; Yoshimura, Masahiro; Tanaka, Tsutomu; Takada, Kanji
2012-03-01
To elucidate drug lipophilicity effects on the bioavailability (BA) of drugs from skin after administration by dissolving microneedles, nine compounds with different lipophilicity indexes (log p value) were formulated into two-layered dissolving microneedles and administered percutaneously to rat skin: desmopressin (DDAVP), sumatriptan (ST), fluorescein (FL), granisetron (GRN), pindolol (PDL), pravastatin (PRV), rhodamine 123 (Rho), rifampicin (RFP), and salmeterol (SLM). Plasma drug concentrations were measured using liquid chromatography-tandem mass spectrometry and spectrofluorometry. In vivo dissolution and diffusion in both horizontal and vertical directions of FL and RH in the skin were studied using fluorescence microscopy. Respective BAs were 95.1 ± 7.9% (DDAVP), 84.2 ± 2.7% (ST), 82.3 ± 7.2% (FL), 82.7 ± 6.7% (GRN), 71.6 ± 3.8% (PDL), 63.6 ± 7.5% (PRV), 53.7 ± 8.3% (Rho), 46.2 ± 6.1% (RFP), and 38.4 ± 2.7% (SM). BA decreased as the lipophilicity index, log p value, of the drug increased from-1.95 to 1.73. The respective remaining percentages in skin tissue were 1.4 ± 0.7% (DDAVP), 0.9 ± 0.1% (ST), 1.0 ± 0.2% (FL), 3.4 ± 1.2% (GRN), 14.5 ± 3.7% (PDL), 23.4 ± 5.2% (PRV), 32.2 ± 6.0% (Rho), 40.7 ± 4.9% (RFP), and 40.6 ± 5.1% (SLM), dependent on log p. Fluorescence microscopy showed no FL or Rho in skin tissue within 4 and 24 h after administration, respectively. The BA of drugs delivered by dissolving microneedles depends on the drug solubility in the skin epidermis and dermis. Copyright © 2011 Wiley Periodicals, Inc.
OBLIQUE VIEW OF NORTHWEST AND NORTHEAST SIDES OF HYDROELECTRIC POWER ...
OBLIQUE VIEW OF NORTHWEST AND NORTHEAST SIDES OF HYDROELECTRIC POWER HOUSE, OLD BYPASS IN BACKGROUND, VIEW TOWARDS SOUTH - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
DETAIL OF WESTINGHOUSE AND B. MORGAN SMITH NAMEPLATES ON ELECTRIC ...
DETAIL OF WESTINGHOUSE AND B. MORGAN SMITH NAMEPLATES ON ELECTRIC GENERATOR IN UPPER LEVEL OF HYDROELECTRIC POWER HOUSE - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
IN VITRO ANDROGENIC ACTIVITY OF KRAFT MILL EFFLUENT
In: Environmental Sciences in the 21st Century: Paradigms, Opportunities, and Challenges: Abstract Book: SETAC 21st Annual Meeting, 12-16 November 2000, Nashville, TN. Society of Environmental Toxicology and Chemistry, Pensacola, FL. Pp. 102.
Female mosquito fish (Gambusia...
OBLIQUE VIEW OF SOUTHEAST AND SOUTHWEST SIDES OF UPPER GATE ...
OBLIQUE VIEW OF SOUTHEAST AND SOUTHWEST SIDES OF UPPER GATE MACHINERY HOUSES WITH HYDROELECTRIC POWER HOUSE IN BACKGROUND - St. Lucie Canal, Lock No. 1, Machinery Houses, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
Distant view from downstream of lock with southeast machinery house, ...
Distant view from downstream of lock with southeast machinery house, SF 109, and timber guide wall on left, exterior view of closed lower lock gates and hydro-electric power house and dam in background, view towards west - St. Lucie Canal, St. Lucie Lock No. 1, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
46 CFR 7.95 - St. Johns Point, FL to Miami Beach, FL.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Inlet Entrance Lighted Whistle Buoy “2”); thence to Jupiter Island bearing approximately 180° true. (h) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet. (i) A line drawn from the seaward extremity of...
46 CFR 7.95 - St. Johns Point, FL to Miami Beach, FL.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Inlet Entrance Lighted Whistle Buoy “2”); thence to Jupiter Island bearing approximately 180° true. (h) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet. (i) A line drawn from the seaward extremity of...
46 CFR 7.95 - St. Johns Point, FL to Miami Beach, FL.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Inlet Entrance Lighted Whistle Buoy “2”); thence to Jupiter Island bearing approximately 180° true. (h) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet. (i) A line drawn from the seaward extremity of...
46 CFR 7.95 - St. Johns Point, FL to Miami Beach, FL.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Inlet Entrance Lighted Whistle Buoy “2”); thence to Jupiter Island bearing approximately 180° true. (h) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet. (i) A line drawn from the seaward extremity of...
50 CFR 600.502 - Vessel reports.
Code of Federal Regulations, 2014 CFR
2014-10-01
..., National Marine Fisheries Service, NOAA, One Blackburn Drive, Gloucester, MA 01930-2298 Director, Northeast Fisheries Science Center, National Marine Fisheries Service, NOAA, 166 Water St., Woods Hole, MA 02543-1097... Region, National Marine Fisheries Service, 263 13th Ave. South, St. Petersburg, FL 33701 Director...
50 CFR 600.502 - Vessel reports.
Code of Federal Regulations, 2012 CFR
2012-10-01
..., National Marine Fisheries Service, NOAA, One Blackburn Drive, Gloucester, MA 01930-2298 Director, Northeast Fisheries Science Center, National Marine Fisheries Service, NOAA, 166 Water St., Woods Hole, MA 02543-1097... Region, National Marine Fisheries Service, 263 13th Ave. South, St. Petersburg, FL 33701 Director...
50 CFR 600.502 - Vessel reports.
Code of Federal Regulations, 2013 CFR
2013-10-01
..., National Marine Fisheries Service, NOAA, One Blackburn Drive, Gloucester, MA 01930-2298 Director, Northeast Fisheries Science Center, National Marine Fisheries Service, NOAA, 166 Water St., Woods Hole, MA 02543-1097... Region, National Marine Fisheries Service, 263 13th Ave. South, St. Petersburg, FL 33701 Director...
1990-01-01
effective ways of promoting U.S. interests. Finally, our Denton Amendment space-available transportation program continues assisting generous American hu... Eglin AFB, FL 9th SOS, Eglin AFB, FL 55th SOS, Eglin AFB, FL 1724th Special Tactics Squadron, Pope AFB, NC 67th SOS, RAF Woodbridge, UK 21st SOS...almost all of which were built from 1962 to 1966 - faced block obsolescence within a decade, and their missiles would not be effective against hardened
1998-01-20
KENNEDY SPACE CENTER, FLA. -- Sea World, Dynamac Life Sciences, and EG&G Protective Services staff tend to a beached whale on the Brevard County shoreline near Kennedy Space Center's Launch Pad 39A. Two pilot whales beached themselves mid-morning on Jan. 20 and were rescued and taken to Marineland near St. Augustine. The two whales, an eight-foot and an 11-foot, bring to six the number of whales being treated at Sea World in Orlando and at Marineland. Nine whales have beached in Brevard County since the beginning of the year.
1998-01-20
KENNEDY SPACE CENTER, FLA. -- Sea World, Dynamac Life Sciences, and EG&G Protective Services staff tend to a beached whale on the Brevard County shoreline near Kennedy Space Center's Launch Pad 39A. Two pilot whales beached themselves mid-morning on Jan. 20 and were rescued and taken to Marineland near St. Augustine. The two whales, an eight-foot and an 11-foot, bring to six the number of whales being treated at Sea World in Orlando and at Marineland. Nine whales have beached in Brevard County since the beginning of the year.
1998-01-20
KENNEDY SPACE CENTER, FLA. -- Sea World, Dynamac Life Sciences, and EG&G Protective Services staff tend to a beached whale on the Brevard County shoreline near Kennedy Space Center's Launch Pad 39A. Two pilot whales beached themselves mid-morning on Jan. 20 and were rescued and taken to Marineland near St. Augustine. The two whales, an eight-foot and an 11-foot, bring to six the number of whales being treated at Sea World in Orlando and at Marineland. Nine whales have beached in Brevard County since the beginning of the year.
1998-01-20
KENNEDY SPACE CENTER, FLA. -- Sea World, Dynamac Life Sciences, and EG&G Protective Services staff tend to a beached whale on the Brevard County shoreline near Kennedy Space Center's Launch Pad 39A. Two pilot whales beached themselves mid-morning on Jan. 20 and were rescued and taken to Marineland near St. Augustine. The two whales, an eight-foot and an 11-foot, bring to six the number of whales being treated at Sea World in Orlando and at Marineland. Nine whales have beached in Brevard County since the beginning of the year.
1998-01-20
KENNEDY SPACE CENTER, FLA. -- Sea World, Dynamac Life Sciences, and EG&G Protective Services staff tend to a beached whale on the Brevard County shoreline near Kennedy Space Center's Launch Pad 39A. Two pilot whales beached themselves mid-morning on Jan. 20 and were rescued and taken to Marineland near St. Augustine. The two whales, an eight-foot and an 11-foot, bring to six the number of whales being treated at Sea World in Orlando and at Marineland. Nine whales have beached in Brevard County since the beginning of the year
1998-01-20
KENNEDY SPACE CENTER, FLA. -- Sea World, Dynamac Life Sciences, and EG&G Protective Services staff tend to a beached whale on the Brevard County shoreline near Kennedy Space Center's Launch Pad 39A. Two pilot whales beached themselves mid-morning on Jan. 20 and were rescued and taken to Marineland near St. Augustine. The two whales, an eight-foot and an 11-foot, bring to six the number of whales being treated at Sea World in Orlando and at Marineland. Nine whales have beached in Brevard County since the beginning of the year.
1998-01-20
KENNEDY SPACE CENTER, FLA. -- Sea World, Dynamac Life Sciences, and EG&G Protective Services staff tend to a beached whale on the Brevard County shoreline near Kennedy Space Center's Launch Pad 39A. Two pilot whales beached themselves mid-morning on Jan. 20 and were rescued and taken to Marineland near St. Augustine. The two whales, an eight-foot and an 11-foot, bring to six the number of whales being treated at Sea World in Orlando and at Marineland. Nine whales have beached in Brevard County since the beginning of the year.
1998-01-20
KENNEDY SPACE CENTER, FLA. -- Sea World, Dynamac Life Sciences, and EG&G Protective Services staff tend to a beached whale on the Brevard County shoreline near Kennedy Space Center's Launch Pad 39A. Two pilot whales beached themselves mid-morning on Jan. 20 and were rescued and taken to Marineland near St. Augustine. The two whales, an eight-foot and an 11-foot, bring to six the number of whales being treated at Sea World in Orlando and at Marineland. Nine whales have beached in Brevard County since the beginning of the year.
1998-01-20
KENNEDY SPACE CENTER, FLA. -- Sea World, Dynamac Life Sciences, and EG&G Protective Services staff tend to a beached whale on the Brevard County shoreline near Kennedy Space Center's Launch Pad 39A. Two pilot whales beached themselves mid-morning on Jan. 20 and were rescued and taken to Marineland near St. Augustine. The two whales, an eight-foot and an 11-foot, bring to six the number of whales being treated at Sea World in Orlando and at Marineland. Nine whales have beached in Brevard County since the beginning of the year.
1993-03-20
photochromic glasses, x - ray absorbing television glasses, extrudablc oriented ceramics, and the ultra-pure materials for optical fibers. While...quartz through the analysis of x - ray diffraction experiments. The repeating nature of the quartz crystal give, many diffraction peaks which allow the...fused silica, which serves as a backbone for most of the silicate glasses. Doris Evans, an x - ray crystallographer at Corning, built a model of fused
Establishment, test and evaluation of a prototype volcano surveillance system
NASA Technical Reports Server (NTRS)
Ward, P. L.; Eaton, J. P.; Endo, E.; Harlow, D.; Marquez, D.; Allen, R.
1973-01-01
A volcano-surveillance system utilizing 23 multilevel earthquake counters and 6 biaxial borehole tiltmeters is being installed and tested on 15 volcanoes in 4 States and 4 foreign countries. The purpose of this system is to give early warning when apparently dormant volcanoes are becoming active. The data are relayed through the ERTS-Data Collection System to Menlo Park for analysis. Installation was completed in 1972 on the volcanoes St. Augustine and Iliamna in Alaska, Kilauea in Hawaii, Baker, Rainier and St. Helens in Washington, Lassen in California, and at a site near Reykjavik, Iceland. Installation continues and should be completed in April 1973 on the volcanoes Santiaguito, Fuego, Agua and Pacaya in Guatemala, Izalco in El Salvador and San Cristobal, Telica and Cerro Negro in Nicaragua.
OBLIQUE VIEW OF NORTHWEST SIDE OF HYDROELECTRIC POWER HOUSE AND ...
OBLIQUE VIEW OF NORTHWEST SIDE OF HYDROELECTRIC POWER HOUSE AND INTERIOR OF SOUTHWEST CORNER OF OLD BYPASS IN FOREGROUND, VIEW TOWARDS SOUTHWEST - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
DOE Office of Scientific and Technical Information (OSTI.GOV)
Maddox, J.J.; Behel, D.; Soileau, J.M.
1996-12-31
Fly ash disposal sites adjacent to fossil fueled generating plants are subject to wind and water erosion which increases the operation and maintenance costs. Gullies and unstable areas in the disposal sites require expensive leveling and filling practices. Test evaluated both warm- and cool-season cover crops established by either sod or seed. Amendments to the ash consisted of composted poultry litter (CPL), soil, soil+CPL, fertilizer and beneficial soil microbes including mycorrhizal fungi. Turf sods (419 Bermuda, Emerald zoysia, and Raleigh St. Augustine) were compared in greenhouse and field studies. Six legumes and 12 grass species were tested in the greenhousemore » as seeded cover crops using similar amendments and raw poultry litter (PL). Legumes grew better with CPL and Boil amendments and grasses grew better on PL and soil amendments possibly due to differences in N requirements and N supply. Cool season crops generally grew faster than warm season species in the greenhouse tests. Amendments should be mixed with the FA to ameliorate the effects of boron and salt toxicity and to increase the water holding capacity. Bermuda sod grew faster than either St, Augustine or Emerald zoysia, but requires more water. A microbial amendment increased dry matter yields of bermuda sod 2 to 3 times after 40 to 60 days over unamended controls. Microbial amendments may be justified on an economic and sustainable basis. A field study is assessing the environmental and cultural requirements to grow a cover crop on an annual basis.« less
Revay, Edita E.; Müller, Gunter C.; Qualls, Whitney A.; Kline, Daniel; Naranjo, Diana P.; Arheart, Kristopher L.; Kravchenko, Vasiliy D.; Yfremova, Zoya; Hausmann, Axel; Beier, John C.; Schlein, Yosef; Xue, Rui-De
2013-01-01
The purpose of this study was to test the efficacy of bait stations and foliar applications containing attractive toxic sugar baits (ATSB) and eugenol to control Aedes albopictus. At the same time the potential impact of these control methods was evaluated on non-target organisms. The study was conducted at five tire sites in St. Augustine, Florida. Aedes albopictus populations were significantly reduced with ATSB-eugenol applications applied directly to non-flowering vegetation and as bait stations compared with non-attractive sugar baits and control. The application of ATSB made to non-flowering vegetation resulted in more significant reductions of mosquito populations compared to the application of ATSB presented in a bait station. Over 5.5% of the non-targets were stained in the flowering vegetation application site. However, when the attractive sugar bait application was made to non-flowering vegetation or presented in bait stations the impact on non-target insects was very low for all non-target orders as only 0.6% of the individual insects were stained with the dye from the sugar solutions, respectively. There were no significant differences between the staining of mosquitoes collected in flowering vegetation (206/1000) or non-flowering vegetation (242/1000) sites during the non-target evaluation. Our field studies support the use of eugenol as an active ingredient for controlling the dengue vector Ae. albopictus when used as an ATSB toxin and demonstrates potential use in sub-tropical and tropical environments for dengue control. PMID:24122115
Working at a Joint-Use Library
ERIC Educational Resources Information Center
Robinson, Carla
2007-01-01
The St. Lucie West Library, also known as the FAU Treasure Coast Campus Library, is a joint-use library facility, with Florida Atlantic University partnering with Indian River Community College and the St. Lucie County (FL) Library System. This article will discuss the circulation, course reserves, interlibrary loan, and collection management…
OBLIQUE VIEW OF SOUTHWEST AND SOUTHEAST SIDES OF UPPER GATE ...
OBLIQUE VIEW OF SOUTHWEST AND SOUTHEAST SIDES OF UPPER GATE MACHINERY HOUSE, NORTH OF LOCK, WITH HYDRO-ELECTRIC POWER HOUSE AND DAM IN BACKGROUND, VIEW TOWARD NORTH NORTHWEST - St. Lucie Canal, Lock No. 1, Machinery Houses, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
NASA Astrophysics Data System (ADS)
Kelly, P. J.; Ketner, D. M.; Kern, C.; Lahusen, R. G.; Lockett, C.; Parker, T.; Paskievitch, J.; Pauk, B.; Rinehart, A.; Werner, C. A.
2015-12-01
In recent years, the USGS Volcano Hazards Program has worked to implement continuous real-time in situ volcanic gas monitoring at volcanoes in the Cascade Range and Alaska. The main goal of this ongoing effort is to better link the compositions of volcanic gases to other real-time monitoring data, such as seismicity and deformation, in order to improve baseline monitoring and early detection of volcanic unrest. Due to the remote and difficult-to-access nature of volcanic-gas monitoring sites in the Cascades and Alaska, we developed Multi-GAS instruments that can operate unattended for long periods of time with minimal direct maintenance from field personnel. Our Multi-GAS stations measure H2O, CO2, SO2, and H2S gas concentrations, are comprised entirely of commercial off-the-shelf components, and are powered by small solar energy systems. One notable feature of our Multi-GAS stations is that they include a unique capability to perform automated CO2, SO2, and H2S sensor verifications using portable gas standards while deployed in the field, thereby allowing for rigorous tracking of sensor performances. In addition, we have developed novel onboard data-processing routines that allow diagnostic and monitoring data - including gas ratios (e.g. CO2/SO2) - to be streamed in real time to internal observatory and public web pages without user input. Here we present over one year of continuous data from a permanent Multi-GAS station installed in August 2014 in the crater of Mount St. Helens, Washington, and several months of data from a station installed near the summit of Augustine Volcano, Alaska in June 2015. Data from the Mount St. Helens Multi-GAS station has been streaming to a public USGS site since early 2015, a first for a permanent Multi-GAS site. Neither station has detected significant changes in gas concentrations or compositions since they were installed, consistent with low levels of seismicity and deformation.
The Obscurantist Design in Saint Augustine's Rhetoric.
ERIC Educational Resources Information Center
Wiethoff, William E.
This paper examines Saint Augustine's obscurantist preferences in popular preaching (as distinguished from his episcopal instructions to other clergy) as a way of identifying one of the classical influences on Christian rhetorical strategy. The first section of the paper offers a comparison of Augustine's theoretical approval of homiletic…
Mau-Moeller, Anett; Behrens, Martin; Finze, Susanne; Bruhn, Sven; Bader, Rainer; Mittelmeier, Wolfram
2014-05-09
The parallel-group randomized active-controlled clinical study was conducted to compare the effectiveness of two in-hospital range of motion (ROM) exercise programs following total knee arthroplasty (TKA). Continuous passive motion (CPM) is frequently used to increase ROM and improve postoperative recovery despite little conclusive scientific evidence. In contrast, a new active sling-based ROM therapy requires the activation of the knee joint muscles and dynamic joint stabilization. It was hypothesized that higher demands on muscle strength and muscle coordination during sling exercise training (ST) might be advantageous for early recovery following TKA. A total of 125 patients undergoing primary TKA were assessed for eligibility. Thirty-eight patients were randomly assigned to receive ST or CPM (control intervention) during hospital stay. Patients were assessed before TKA for baseline measurement (pretest), 1 day before discharge (posttest) and 3 months after TKA (follow-up). The passive knee flexion range of motion (pFL) was the primary outcome measure. Secondary outcome measures included active knee flexion range of motion, active and passive knee extension ROM, static postural control, physical activity, pain, length of hospital stay as well as clinical, functional and quality-of-life outcomes (SF-36, HSS and WOMAC scores). Data were analyzed according to the intention-to-treat principle. Differences between the groups were tested for significance by the unpaired Student's t test or an analysis of covariance (ANCOVA) adjusted for baseline, weight, sex, age, pain and physical activity. A between-group difference could be determined at posttest. The pFL was significantly higher by 6.0° (95% CI 0.9 to 11.2°; P = 0.022) in the ST group. No difference between groups in pFL was documented at follow-up. Furthermore, no significant differences could be observed for any secondary outcome measure at posttest and follow-up. ST seems to have a clinically relevant beneficial short-term effect on pFL compared to CPM. The results support the implementation of ST in rehabilitation programs following TKA. Therapy, level 2b.
Murray, Louis C.
2009-01-01
Water-use data collected between 1992 and 2006 at eight municipal water-supply utilities in east-central and northeast Florida were analyzed to identify seasonal trends in use and to quantify monthly variations. Regression analyses were applied to identify significant correlations between water use and selected meteorological parameters and drought indices. Selected parameters and indices include precipitation (P), air temperature (T), potential evapotranspiration (PET), available water (P-PET), monthly changes in these parameters (Delta P, Delta T, Delta PET, Delta(P-PET), the Palmer Drought Severity Index (PDSI), and the Standardized Precipitation Index (SPI). Selected utilities include the City of Daytona Beach (Daytona), the City of Eustis (Eustis), Gainesville Regional Utilities (GRU), Jacksonville Electric Authority (JEA), Orange County Utilities (OCU), Orlando Utilities Commission (OUC), Seminole County Utilities (SCU), and the City of St. Augustine (St. Augustine). Water-use rates at these utilities in 2006 ranged from about 3.2 million gallons per day at Eustis to about 131 million gallons per day at JEA. Total water-use rates increased at all utilities throughout the 15-year period of record, ranging from about 4 percent at Daytona to greater than 200 percent at OCU and SCU. Metered rates, however, decreased at six of the eight utilities, ranging from about 2 percent at OCU and OUC to about 17 percent at Eustis. Decreases in metered rates occurred because the number of metered connections increased at a greater rate than did total water use, suggesting that factors other than just population growth may play important roles in water-use dynamics. Given the absence of a concurrent trend in precipitation, these decreases can likely be attributed to changes in non-climatic factors such as water-use type, usage of reclaimed water, water-use restrictions, demographics, and so forth. When averaged for the eight utilities, metered water-use rates depict a clear seasonal pattern in which rates were lowest in the winter and greatest in the late spring. Averaged water-use rates ranged from about 9 percent below the 15-year daily mean in January to about 11 percent above the daily mean in May. Water-use rates were found to be statistically correlated to meteorological parameters and drought indices, and to be influenced by system memory. Metered rates (in gallons per day per active metered connection) were consistently found to be influenced by P, T, PET, and P-PET and changes in these parameters that occurred in prior months. In the single-variant analyses, best correlations were obtained by fitting polynomial functions to plots of metered rates versus moving-averaged values of selected parameters (R2 values greater than 0.50 at three of eight sites). Overall, metered water-use rates were best correlated with the 3- to 4-month moving average of Delta T or Delta PET (R2 values up to 0.66), whereas the full suite of meteorological parameters was best correlated with metered rates at Daytona and least correlated with rates at St. Augustine. Similarly, metered rates were substantially better correlated with moving-averaged values of precipitation (significant at all eight sites) than with single (current) monthly values (significant at only three sites). Total and metered water-use rates were positively correlated with T, PET, Delta P, Delta T, and Delta PET, and negatively correlated with P, P-PET, Delta (P-PET), PDSI, and SPI. The drought indices were better correlated with total water-use rates than with metered rates, whereas metered rates were better correlated with meteorological parameters. Multivariant analyses produced fits of the data that explained a greater degree of the variance in metered rates than did the single-variant analyses. Adjusted R2 values for the 'best' models ranged from 0.79 at JEA to 0.29 at St. Augustine and exceeded 0.60 at five of eight sites. The amount of available water (P-PET) was the si
NASA Astrophysics Data System (ADS)
Ward, N. D.; Osborne, T.; Dye, T.; Julian, P.
2017-12-01
The last several years have been marked by a high incidence of Atlantic tropical cyclones making landfall as powerful hurricanes or tropical storms. For example, in 2016 Hurricane Matthew devastated parts of the Caribbean and the southeastern United States. In 2017, this region was further battered by hurricanes Irma and Maria. Here, we present water quality data collected in the intracoastal waterway near the Whitney Lab for Marine Bioscience during hurricanes Matthew and Irma, a region that experienced flooding during both storms. YSI Exo 2 sondes were deployed to measure pH, salinity, temperature, dissolved O2, fluorescent dissolved organic matter (fDOM), turbidity, and Chlorophyll-a (Chl-a) on a 15 minute interval. The Hurricane Matthew sonde deployment failed as soon as the storm hit, but revealed an interesting phenomenon leading up to the storm that was also observed during Irma. Salinity in the intracoastal waterway (off the Whitney Lab dock) typically varies from purely marine to 15-20 psu throughout the tidal cycle. However, several days before both storms approached the Florida coast (i.e. when they were near the Caribbean), the salinity signal became purely marine, overriding any tidal signal. Anecdotally, storm drains were already filled up to street level prior to the storm hitting, poising the region for immense flooding and storm surge. The opposite effect was observed after Irma moved past FL. Water became much fresher than normal for several days and it took almost a week to return to "normal" salinity tidal cycles. As both storms hit, turbidity increased by an order of magnitude for a several hour period. fDOM and O2 behaved similar to salinity during and after Irma, showing a mostly marine signal (e.g. higher O2, lower fDOM) in the lead up, and brief switch to more freshwater influence the week after the storm. Chl-a peaked several days after the storm, presumably due to mobilization of nutrient rich flood and waste waters and subsequent algae blooms. These results demonstrate the power of tropical cyclones in altering aquatic biogeochemical conditions days ahead of any noticeable impact and provide a preliminary look at how these events may influence factors such as carbon export and cycling.
VERTICAL DETAIL OBLIQUE VIEW OF NORTHEAST SIDE OF HYDROELECTRIC POWER ...
VERTICAL DETAIL OBLIQUE VIEW OF NORTHEAST SIDE OF HYDROELECTRIC POWER HOUSE WITH OLD BYPASS IN FOREGROUND, SHOWING GLASS BLOCKS PROVIDING LIGHT TO BASEMENT OF HYDROELECTRIC POWER HOUSE, VIEW TOWARDS WEST SOUTHWEST - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
OBLIQUE VIEW OF SOUTHWEST AND SOUTHEAST SIDES OF HYDROELECTRIC POWER ...
OBLIQUE VIEW OF SOUTHWEST AND SOUTHEAST SIDES OF HYDROELECTRIC POWER HOUSE WITH DAM TO LEFT OF HYDROELECTRIC POWER HOUSE AND ENTRANCE TO OLD LOCK CHAMBER ON RIGHT, VIEW TOWARDS NORTH - St. Lucie Canal, Lock No. 1, Hydroelectric Power House, St. Lucie, Cross State Canal, Okeechobee Intracoastal Waterway, Stuart, Martin County, FL
19 CFR 101.3 - Customs service ports and ports of entry.
Code of Federal Regulations, 2012 CFR
2012-04-01
.... 56420. Arizona Douglas Including territory described in E.O. 9382, Sept. 25, 1943 (8 FR 13083....D. 68-67. Florida Fernandina Beach Including St. Mary's, GA; T.D. 53033. Fort Myers T.D. 99-9.... 55548. Brunswick Including territory described in T.D. 86-162. Fernandina Beach, FL Including St. Mary's...
19 CFR 101.3 - Customs service ports and ports of entry.
Code of Federal Regulations, 2014 CFR
2014-04-01
.... 56420. Arizona Douglas Including territory described in E.O. 9382, Sept. 25, 1943 (8 FR 13083....D. 68-67. Florida Fernandina Beach Including St. Mary's, GA; T.D. 53033. Fort Myers T.D. 99-9.... 55548. Brunswick Including territory described in T.D. 86-162. Fernandina Beach, FL Including St. Mary's...
19 CFR 101.3 - Customs service ports and ports of entry.
Code of Federal Regulations, 2013 CFR
2013-04-01
.... 56420. Arizona Douglas Including territory described in E.O. 9382, Sept. 25, 1943 (8 FR 13083....D. 68-67. Florida Fernandina Beach Including St. Mary's, GA; T.D. 53033. Fort Myers T.D. 99-9.... 55548. Brunswick Including territory described in T.D. 86-162. Fernandina Beach, FL Including St. Mary's...
19 CFR 101.3 - Customs service ports and ports of entry.
Code of Federal Regulations, 2010 CFR
2010-04-01
.... 56420. Arizona Douglas Including territory described in E.O. 9382, Sept. 25, 1943 (8 FR 13083....D. 68-67. Florida Fernandina Beach Including St. Mary's, GA; T.D. 53033. Fort Myers T.D. 99-9.... 55548. Brunswick Including territory described in T.D. 86-162. Fernandina Beach, FL Including St. Mary's...
19 CFR 101.3 - Customs service ports and ports of entry.
Code of Federal Regulations, 2011 CFR
2011-04-01
.... 56420. Arizona Douglas Including territory described in E.O. 9382, Sept. 25, 1943 (8 FR 13083....D. 68-67. Florida Fernandina Beach Including St. Mary's, GA; T.D. 53033. Fort Myers T.D. 99-9.... 55548. Brunswick Including territory described in T.D. 86-162. Fernandina Beach, FL Including St. Mary's...
33 CFR 165.720 - Safety/Security Zone: St. Johns River, Jacksonville, FL.
Code of Federal Regulations, 2014 CFR
2014-07-01
... vessel during its transit of the St. Johns River and out to three (3) nautical miles offshore. (b...: (1) All waters within 200 yards of Blount Island, Jacksonville, Florida and all adjacent land within 100 yards of the island shoreline during staging of Department of Defense equipment and during the...
33 CFR 165.720 - Safety/Security Zone: St. Johns River, Jacksonville, FL.
Code of Federal Regulations, 2011 CFR
2011-07-01
... vessel during its transit of the St. Johns River and out to three (3) nautical miles offshore. (b...: (1) All waters within 200 yards of Blount Island, Jacksonville, Florida and all adjacent land within 100 yards of the island shoreline during staging of Department of Defense equipment and during the...
33 CFR 165.720 - Safety/Security Zone: St. Johns River, Jacksonville, FL.
Code of Federal Regulations, 2012 CFR
2012-07-01
... vessel during its transit of the St. Johns River and out to three (3) nautical miles offshore. (b...: (1) All waters within 200 yards of Blount Island, Jacksonville, Florida and all adjacent land within 100 yards of the island shoreline during staging of Department of Defense equipment and during the...
33 CFR 165.720 - Safety/Security Zone: St. Johns River, Jacksonville, FL.
Code of Federal Regulations, 2013 CFR
2013-07-01
... vessel during its transit of the St. Johns River and out to three (3) nautical miles offshore. (b...: (1) All waters within 200 yards of Blount Island, Jacksonville, Florida and all adjacent land within 100 yards of the island shoreline during staging of Department of Defense equipment and during the...
1993-02-01
Spectrum The vibrational IR spectra of formaldeh.de and its deuterated species have been measured by a number of groups and analyzed in several studies ... studies [23-28]. The order of the frontier (r) orbitals, a textbook example for simple group theory arguments, is determined by the high symmetry (Dy...simplexes will give a structure with octahedral symmetr\\ since the subgroup of the Coxeter group which leaves one component of a four -vector invariant
Two beached pilot whales are rescued by KSC and Sea World staff members near Launch Pad 39A
NASA Technical Reports Server (NTRS)
1998-01-01
Sea World, Dynamac Life Sciences, and EG&G Protective Services staff tend to a beached whale on the Brevard County shoreline near Kennedy Space Center's Launch Pad 39A. Two pilot whales beached themselves mid-morning on Jan. 20 and were rescued and taken to Marineland near St. Augustine. The two whales, an eight- foot and an 11-foot, bring to six the number of whales being treated at Sea World in Orlando and at Marineland. Nine whales have beached in Brevard County since the beginning of the year.
1991-08-01
Southeastern Center for Electrical Engineering REPORT NUMBER Education (SCEEE) 11th and Massachusetts Avenues St Cloud , FL 34769 D T |C 9. SPONSORING...performing the report. Self-explanatory. Enter U.S. Security Classification in accordance with U.S. Security Block 9. S Qonsorin/ Monitorig Aaencv
USDA-ARS?s Scientific Manuscript database
Natural phenology and development of the cactus moth, Cactoblastis cactorum (Berg) (Lepidoptera: Pyralidae) was studied under field conditions in St. Marks National Wildlife Refuge, St. Marks, FL. from July 2006 to September 2007. Cactus pads (Opuntia stricta Haw. [Cactaceae]) were visually surveyed...
In: Environmental Sciences in the 21st Century: Paradigms, Opportunities, and Challenges: Abstract Book: SETAC 21st Annual Meeting, 12-16 November 2000, Nashville, TN. Society of Environmental Toxicology and Chemistry, Pensacola, FL. Pp. p. 262. (ERL,GB R816).
Various i...
ERIC Educational Resources Information Center
Miles, Eleanor; Sheeran, Paschal; Webb, Thomas L.
2013-01-01
Augustine and Hemenover (2013) were right to state that meta-analyses should be accurate and generalizable. However, we disagree that our meta-analysis of emotion regulation strategies (Webb, Miles, & Sheeran, 2012) fell short in these respects. Augustine and Hemenover's concerns appear to have accrued from misunderstandings of our inclusion…
2009-07-30
CAPE CANAVERAL, Fla. – Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., is seated at the conference table for the Augustine Commission, meeting in Cocoa Beach, Fla. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Augustine, the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Jim Grossmann
Code of Federal Regulations, 2011 CFR
2011-10-01
... (RA) for the purposes of this part, means the Administrator, Southeast Region, NMFS, 9721 Executive Center Drive N., St. Petersburg, FL 33702, or a designee. Stone crab means Menippe mercenaria, M. adina...
Atmospheric contribution of gas emissions from Augustine volcano, Alaska during the 2006 eruption
McGee, K.A.; Doukas, M.P.; McGimsey, R.G.; Neal, C.A.; Wessels, R.L.
2008-01-01
Airborne surveillance of gas emissions from Augustine for SO2, CO2 and H2S showed no evidence of anomalous degassing from 1990 through May 2005. By December 20, 2005, Augustine was degassing 660 td-1 of SO2, and ten times that by January 4, 2006. The highest SO2 emission rate measured during the 2006 eruption was 8650 td-1 (March 1); for CO2, 13000 td-1 (March 9), and H2S, 8 td-1 (January 19). Thirty-four SO2 measurements were made from December 2005 through 2006, with 9 each for CO2 and H2S. Augustine released 1 ?? 106 tonnes of CO2 to the atmosphere during 2006, a level similar to the output of a medium-sized natural gas-fired power plant, and thus was not a significant contributor of greenhouse gas to the atmosphere compared to anthropogenic sources. Augustine released about 5 ?? 105 tonnes of SO2 during 2006, similar to that released in 1976 and 1986.
Pauk, Benjamin A.; Power, John A.; Lisowski, Mike; Dzurisin, Daniel; Iwatsubo, Eugene Y.; Melbourne, Tim
2001-01-01
Between August 3 and 8,2000,the Alaska Volcano Observatory completed a Global Positioning System (GPS) survey at Augustine Volcano, Alaska. Augustine is a frequently active calcalkaline volcano located in the lower portion of Cook Inlet (fig. 1), with reported eruptions in 1812, 1882, 1909?, 1935, 1964, 1976, and 1986 (Miller et al., 1998). Geodetic measurements using electronic and optical surveying techniques (EDM and theodolite) were begun at Augustine Volcano in 1986. In 1988 and 1989, an island-wide trilateration network comprising 19 benchmarks was completed and measured in its entirety (Power and Iwatsubo, 1998). Partial GPS surveys of the Augustine Island geodetic network were completed in 1992 and 1995; however, neither of these surveys included all marks on the island.Additional GPS measurements of benchmarks A5 and A15 (fig. 2) were made during the summers of 1992, 1993, 1994, and 1996. The goals of the 2000 GPS survey were to:1) re-measure all existing benchmarks on Augustine Island using a homogeneous set of GPS equipment operated in a consistent manner, 2) add measurements at benchmarks on the western shore of Cook Inlet at distances of 15 to 25 km, 3) add measurements at an existing benchmark (BURR) on Augustine Island that was not previously surveyed, and 4) add additional marks in areas of the island thought to be actively deforming. The entire survey resulted in collection of GPS data at a total of 24 sites (fig. 1 and 2). In this report we describe the methods of GPS data collection and processing used at Augustine during the 2000 survey. We use this data to calculate coordinates and elevations for all 24 sites surveyed. Data from the 2000 survey is then compared toelectronic and optical measurements made in 1988 and 1989. This report also contains a general description of all marks surveyed in 2000 and photographs of all new marks established during the 2000 survey (Appendix A).
NASA Astrophysics Data System (ADS)
McAlpin, D. B.; Meyer, F. J.; Lu, Z.; Beget, J. E.
2014-12-01
Augustine Island is a small, 8x11 km island in South Central Alaska's lower Cook Inlet. It is approximately 280 km southwest of Anchorage, and occupied entirely by its namesake Augustine Volcano. At Augustine Volcano, SAR data suitable for interferometry is available from 1992 to 2005, from March 2006 to April 2007, and from July 2007 to October 2010. Its last two eruptive episodes, in 1986 and 2006, resulted in substantial pyroclastic flow deposits (PFDs) on the Volcano's north flank. Earlier InSAR analyses of the area, from 1992-1999, identified local subsidence, but no volcano-wide deformation indicative of magma-chamber evacuation. In contrast to previous studies, we use InSAR data to determine a range of geophysical parameters for PFDs emplaced during the Augustine's two most recent eruption cycles. Based on InSAR measurements between 1992 and 2010, we reconstruct the deformation behavior of PFDs emplaced during Augustine's last two eruption cycles. Using a combination of InSAR measurements and modeling, we determine the thickness and long-term deformation of overlaying pyroclastic flow deposits emplaced in 1986 and 2006. Consistent with previous observations of pyroclastic flows, we found that the PFDs on Augustine Island rapidly subsided after emplacement due to an initial compaction of the material. We determined the length of this initial settling period and measured the compaction rate. Subsequent to this initial rapid subsidence, we found that PFD deformation slowed to a more persistent, linear, long-term rate, related to cooling of the deposits. We established that the deposits' contraction rate is linearly related to their thickness and measured the contraction rate. Finally, a study of long term coherence properties of the Augustine PFDs showed remarkable stability of the surface over long time periods. This information provides clues on the structural properties and composition of the emplaced material.
SAR measurements of surface displacements at Augustine Volcano, Alaska from 1992 to 2005
Lee, C.-W.; Lu, Z.; Kwoun, Oh-Ig
2007-01-01
Augustine volcano is an active stratovolcano located at the southwest of Anchorage, Alaska. Augustine volcano had experienced seven significantly explosive eruptions in 1812, 1883, 1908, 1935, 1963, 1976, and 1986, and a minor eruption in January 2006. We measured the surface displacements of the volcano by radar interferometry and GPS before and after the eruption in 2006. ERS-1/2, RADARSAT-1 and ENVISAT SAR data were used for the study. Multiple interferograms were stacked to reduce artifacts caused by different atmospheric conditions. Least square (LS) method was used to reduce atmospheric artifacts. Singular value decomposition (SVD) method was applied for retrieval of time sequential deformations. Satellite radar interferometry helps to understand the surface displacements system of Augustine volcano. ?? 2007 IEEE.
SAR measurements of surface displacements at Augustine Volcano, Alaska from 1992 to 2005
Lee, C.-W.; Lu, Z.; Kwoun, Oh-Ig
2008-01-01
Augustine volcano is an active stratovolcano located at the southwest of Anchorage, Alaska. Augustine volcano had experienced seven significantly explosive eruptions in 1812, 1883, 1908, 1935, 1963, 1976, and 1986, and a minor eruption in January 2006. We measured the surface displacements of the volcano by radar interferometry and GPS before and after the eruption in 2006. ERS-1/2, RADARSAT-1 and ENVISAT SAR data were used for the study. Multiple interferograms were stacked to reduce artifacts caused by different atmospheric conditions. Least square (LS) method was used to reduce atmospheric artifacts. Singular value decomposition (SVD) method was applied for retrieval of time sequential deformations. Satellite radar interferometry helps to understand the surface displacements system of Augustine volcano. ?? 2007 IEEE.
... MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods . 23rd ed. St Louis, MO: Elsevier; 2017:chap 44. Review Date 5/20/2016 Updated by: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. ...
Code of Federal Regulations, 2010 CFR
2010-10-01
..., DEPARTMENT OF COMMERCE STONE CRAB FISHERY OF THE GULF OF MEXICO General Measures § 654.2 Definitions. In... Center Drive N., St. Petersburg, FL 33702, or a designee. Stone crab means Menippe mercenaria, M. adina...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-28
... Naples, St. Petersburg, Cape Coral, and Sarasota, Florida. These safety zones are necessary to protect...:30 a.m. on January 1, 2012. 3. Cape Coral, Florida. All waters within a 235 yard radius of position...:30 a.m. on January 1, 2012. (3) Cape Coral, FL. All waters within a 235 yard radius of position 26...
Natural gas seeps in the French Alps: Sources and pathways
NASA Astrophysics Data System (ADS)
Kloppmann, Wolfram; Blessing, Michaela; Proust, Eric; Gal, Frédéric; Bentivegna, Gaetan; Henry, Benoit; Defossez, Pierrick; Catherine, Lerouge; Humez, Pauline; Mayer, Bernhard; Millot, Romain; Gaucher, Eric
2016-04-01
Natural gas emanations are part of the geochemical baseline to take into account when assessing global greenhouse gas emissions and potential impacts of conventional and unconventional gas exploration and exploitation on groundwater. Examples of such natural gas macro-seeps are known in several parts of the world (Etiope et al., 2009). Only a limited number of them have been characterized for their gas and isotopic compositions. Such analyses can provide essential information for baseline studies, providing insight in the sources (biogenic vs. thermogenic or modified thermogenic) and pathways of such seeps and may allow for distinction of natural seeps from stray gas leakage associated with human activities. Here, we report gas concentrations and multi-isotope data (δ13C and δ2H of methane and ethane, δ13C and δ18O of CO2, 3He/4He ratio) of two gas seeps in the French subalpine chains, both in a similar geological and structural position within Middle Jurassic claystones along the eastern border of the large synclinal structures of the Vercors and the Chartreuse massifs (Moss, 1992). The "ardent fountain" (fontaine ardente) of Le Gua, 30 km south of Grenoble has most likely the longest continuous written record of existence of any individual natural gas seep, mentioned explicitly as early as the first quarter of the 5th century (Augustin of Hippo (St. Augustin), approx. 426) This natural seep was described in the past as a "wet seep" associated with a spring, whereas the second investigated seep, Rochasson near Meylan north of Grenoble, is a dry seep. Both seeps contain methane and ethane with thermogenic C and H isotope signatures, comparable with a seep in the Northern Swiss Alps at Giswil (Etiope et al., 2010) but with a higher dryness (C1/(C2+C3)>1000) for the Le Gua seep, possibly due to molecular fractionation upon advective fluid+gas migration (Etiope et al., 2009). Maturity (R0) of the reservoir rocks deduced from δ13C(CH4), δ13C(C2H6) is similar to values found by Moss (1992) for West-alpine Oxfordian shales. CO2 contents of <9% could stem from methane oxidation. He isotope ratios are radiogenic with only minor mantle contributions, as it is typical for the Western Alps (Marty et al., 1992). This preliminary investigation reveals that thermogenic natural gas can migrate naturally to the surface in significant flux rates over millenaries without anthropogenic causes, in cases that appropriate leakage pathways exist. This study was co-funded by French ANR and Canadian NSERC. ND_ABSTRACT@ Etiope G., Feyzullayev A., Baciu C. L. (2009) Marine and Petroleum Geology, 26, 333-344. Etiope G., Zwahlen C., Anselmetti F. S., Kipfer R., Schubert C. J. (2010) Geofluids, 10, 476-485. Marty B., Onions R. K., Oxburgh E. R., Martel D., Lombardi S. (1992) Tectonophysics, 206, 71-78. Moss S. (1992) Journal of the Geological Society, 149, 503-515. Augustin of Hippo (St. Augustin) (approx. 426) De Civitate Dei contra paganos, Vol. Liber XXI, chap. VII
NASA Astrophysics Data System (ADS)
Millar, C. I.; Westfall, R. D.; Delany, D. L.
2010-12-01
Widespread forest mortality in high-elevation forests has been increasing across western North American mountains in recent years, with climate, insects, and disease the primary causes. Subalpine forests in the eastern Sierra Nevada, by contrast, have experienced far less mortality than other ranges, and mortality events have been patchy and episodic. This situation, and lack of significant effect of non-native white-pine blister rust, enable investigation of fine-scale response of two subalpine Sierran species, whitebark pine (Pinus albicaulis, PiAl) and limber pine (P. flexilis, PiFl), to climate variability. We report similarities and differences between the two major mortality events in these pines in the last 150 years: 1988-1992 for PiFl and 2006-ongoing for PiAl. In both species, the events occurred within monotypic, closed-canopy, relatively young stands (< 200 yrs PiAl, < 300 yrs in PiFl); were localized to central-eastern Sierra Nevada; and occurred at 2740-2840 m along the eastern edge of the escarpment on north/northeast aspects with slopes > 40%. Mortality patches averaged 40-80 ha in both species, with mean stand mortality of trees > 10 cm diameter 91% in PiAl and 60% in PiFl. The ultimate cause of tree death was mountain pine beetle (Dendroctonus ponderosae) in both species, with increasing 20th/21st C minimum temperatures combined with drought the pre-conditioning factors. Overall growth in the past 150 years suggests that PiFl is more drought hardy than PiAl but responds sensitively to the combined effects of drought and increasing warmth. After the 1988-1992 drought, surviving PiFl recovered growth. PiAl trees grew very poorly during that drought, and continued poor growth in the years until 2006 when the mortality event occurred in PiAl. A significant species effect is the apparent difference in levels of within-stand genetic diversity for climate factors. Differential growth between 19th C (cool, wet) and 20th/21st C (warming, drying) of PiFl trees that died versus survivors indicates that considerable within-stand genetic diversity for climate existed in PiFl. For PiFl, the late 20th C mortality event acted as strong natural selection to improve within-stand fitness for warmer and drier conditions. PiFl trees that survived the 1988-1992 drought remained healthy through subsequent droughts, including the drought that is currently causing PiAl mortality. By contrast, the PiAl stands do not appear to have contained adaptive genetic diversity for drought and warmth, and PiAl trees growth behavior over the past 150 years was similar in pattern to the PiFl trees that died. As a result, the mortality event in PiAl is creating forest openings, with unknown future stand conditions, rather than rapid within-species adaptation that occurred in PiFl.
12. Interior detail of bridge operator's house showing generator and ...
12. Interior detail of bridge operator's house showing generator and bridge operator, Mr. Gene Amonette, facing west. - Palm Valley Bridge, County Road 210 spanning Intracoastal Waterway, Ponte Vedra Beach, St. Johns County, FL
75 FR 29205 - Changes in Flood Elevation Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-25
... Business Review. Collins Avenue, Suite 250, Sunny Isles Beach, FL 33160. Osceola City of St. Cloud (09... Morrow (09-04- February 12, 2010; The Honorable Jim June 21, 2010 130045 4735P). Februrary 19, 2010...
Excessive Cap-dependent Translation as a Molecular Mechanism Underlying ASD
2014-10-01
LSD acp HDB df SFO PVA S1FL I BSTMPM BSTMPI BSTMPL MCPO VP BSTLP...LGP Cl Pir VEn ACo SCh LOT cg vhc sm st ec ic rf I f IPACL AAV S1DZ TS SFi IPACM AC MPOL MPOM LSD acp HDB df SFO PVA S1FL I BSTMPM BSTMPI BSTMPL MCPO VP...Sweet, H.McDermid, S. R. Shaw , J. Claytor, J. Willis, D. P. Kelly, 22q13 deletion syndrome. Am. J. Med. Genet. 101, 91–99 (2001). 90. S. U. Dhar,
Badal, Simone; Collins-Fairclough, Aneisha; Stewart, Cheryl; Smith, Keriayn
2014-10-01
The 2nd Annual Conference of the Society for Scientific Advancement (SoSA) was convened to integrate three research areas towards the development of therapies that will help to reduce disease burden in the Caribbean. Held in Kingston, the capital city of Jamaica, on November 22, 2013, the meeting assembled experts in the areas of genomics, stem cell research and natural medicine. The speakers represented the University of the West Indies, Mona and St. Augustine campuses, the University of Technology, and faculty from the USA and Africa. Sponsorship of this meeting supports SoSA's goal of stimulating translational research in the Caribbean.
Augustine Volcano, Cook Inlet, Alaska January 31, 2006
2006-02-02
Since last spring, the U.S. Geological Survey Alaska Volcano Observatory AVO has detected increasing volcanic unrest at Augustine Volcano in Cook Inlet, Alaska near Anchorage. This image is from NASA Terra spacecraft.
Augustine Volcano, Cook Inlet, Alaska January 12, 2006
2006-02-02
Since last spring, the U.S. Geological Survey Alaska Volcano Observatory AVO has detected increasing volcanic unrest at Augustine Volcano in Cook Inlet, Alaska near Anchorage. This image is from NASA Terra spacecraft.
Volcanic tsunamis and prehistoric cultural transitions in Cook Inlet, Alaska
Beget, J.; Gardner, C.; Davis, K.
2008-01-01
The 1883 eruption of Augustine Volcano produced a tsunami when a debris avalanche traveled into the waters of Cook Inlet. Older debris avalanches and coeval paleotsunami deposits from sites around Cook Inlet record several older volcanic tsunamis. A debris avalanche into the sea on the west side of Augustine Island ca. 450??years ago produced a wave that affected areas 17??m above high tide on Augustine Island. A large volcanic tsunami was generated by a debris avalanche on the east side of Augustine Island ca. 1600??yr BP, and affected areas more than 7??m above high tide at distances of 80??km from the volcano on the Kenai Peninsula. A tsunami deposit dated to ca. 3600??yr BP is tentatively correlated with a southward directed collapse of the summit of Redoubt Volcano, although little is known about the magnitude of the tsunami. The 1600??yr BP tsunami from Augustine Volcano occurred about the same time as the collapse of the well-developed Kachemak culture in the southern Cook Inlet area, suggesting a link between volcanic tsunamis and prehistoric cultural changes in this region of Alaska. ?? 2008 Elsevier B.V.
NASA Astrophysics Data System (ADS)
Humberston, J. L.; McNinch, J.; Lippmann, T. C.
2016-12-01
The morphology of tidal inlet ebb-shoals varies dynamically over time, particularly in response to large wave events. Understanding which wave qualities most influence shoals' evolution would support advancements in sediment bypassing models as well as targeted maintenance dredging for hydrographic purposes. Unfortunately, shallow and rapidly changing bathymetry, turbid waters and ambiguous wave speeds resulting from multiple shoaling and de-shoaling areas limits many traditional surveying techniques from obtaining the spatial and temporal resolution necessary to effectively characterize shoal development. The Radar Inlet Observing System (RIOS) is a uniquely designed mobile X-band radar system that can be deployed to inlet environments and, using roof-mounted solar panels and an automatically triggered highly efficient diesel generator, run automated hourly collections and wirelessly stream data for up to several months at a time in nearly all weather and water conditions. During 2015 and early 2016, RIOS was deployed to St. Augustine Inlet, FL., New River Inlet, N.C., and Oregon Inlet, N.C. for periods of one to six months to allow for measureable shoal evolution. During deployments, ten minute collections (at 1 Hz) were conducted every hour and the data gridded to a 5m alongshore/cross-shore grid. Raw intensity returns were time-averaged and analyzed to define three metrics of shoal evolution: movement direction, movement velocity and inferred bathymetry. For each location and time period, wave frequencies, wave directions and significant wave heights were collected from the nearest wave-buoy. Time lapse videos of shoal positions were inspected and used in concert with cross-correlations values from each pair of shoal and wave parameters to determine the incident wave qualities most strongly relating to shoal evolution. Preliminary results suggest wave height, more than frequency, controls shoal movement. Wave direction and size collaboratively appear to direct the shoal's alongshore movement direction as well as general trends of morphologic evolution.
The 47th annual Florida pesticide residue workshop
USDA-ARS?s Scientific Manuscript database
This is an introductory article to a special section of the Journal of Agricultural and Food Chemistry consisting of publications from the 47th Annual Florida Pesticide Residue Workshop held in St. Pete Beach, FL in July of 2010....
Musser, Jonathan W.
2018-01-31
Digital flood-inundation maps for a 12.6-mile reach of the Withlacoochee River from Skipper Bridge Road to St. Augustine Road (Georgia State Route 133) were developed to depict estimates of the areal extent and depth of flooding corresponding to selected water levels (stages) at the U.S. Geological Survey (USGS) streamgage at Withlacoochee River at Skipper Bridge Road, near Bemiss, Ga. (023177483). Real-time stage information from this streamgage can be used with these maps to estimate near real-time areas of inundation. The forecasted peak-stage information for the USGS streamgage at Withlacoochee River at Skipper Bridge Road, near Bemiss, Ga. (023177483), can be used in conjunction with the maps developed for this study to show predicted areas of flood inundation.A one-dimensional step-backwater model was developed using the U.S. Army Corps of Engineers Hydrologic Engineer-ing Center’s River Analysis System (HEC–RAS) software for the Withlacoochee River and was used to compute flood profiles for a 12.6-mile reach of the Withlacoochee River. The hydraulic model was then used to simulate 23 water-surface profiles at 1.0-foot (ft) intervals at the Withlacoochee River near the Bemiss streamgage. The profiles ranged from the National Weather Service action stage of 10.7 ft, which is 131.0 ft above the North American Vertical Datum of 1988 (NAVD 88), to a stage of 32.7 ft, which is 153.0 ft above NAVD 88. The simulated water-surface profiles were then combined with a geographic information system digital elevation model—derived from light detection and ranging (lidar) data having a 4.0-ft horizontal resolution—to delineate the area flooded at each 1.0-ft interval of stream stage.
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2012-10-02
... possible to benefit refuge wildlife. Under Alternative C, we will expand management of wood storks and..., hiking, and bicycling. Bicycling that does not support appropriate and compatible uses, such as mountain...
Hegab, Moustafa; Midan, Mahmoud Farouk; Taha, Tamer; Bibars, Mamdouh; Wakeel, Khaled Helmi El; Amer, Hesham; Azmy, Osama
2018-05-20
To construct new fetal biometric charts and equations for some fetal biometric parameters for women between 12 th and 41 st weeks living in Ismailia and Port Said Governorates in Egypt. This cross-sectional study was carried out on 656 Egyptian women (from Ismailia and Port Said governorates) with an uncomplicated pregnancy, and all were sure of their dates. The selected group was between the 12 th and 41 st weeks of gestation, recruited from the district general hospital in Ismailia and Port Said to measure ultrasonographically biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC) and femur length (FL), then for each measurement separate regression models were fitted to estimate both the mean and the Standard deviation at each gestational age. New Egyptian charts were reported for BPD, HC, AC, and FL. Reference equations for the dating of pregnancy were presented. The mean of the previous measurements at 12 th and 41 st weeks were as follows: (23.37, 98.72), (83.05, 336.12), (67.85, 332.57) and (12.50, 74.92) respectively. New fetal biometric charts and regression equations for pregnant women living in Port Said & Ismailia governorates in Egypt.
75 FR 62810 - Twenty-Fourth Update of the Federal Agency Hazardous Waste Compliance Docket
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2010-10-13
... Alliance CCAFS Beach Road CCAFS FL 32920-9 Air Force 3010 19A Delta IV Program. 009 Transportation Security.... 171st Air Refueling Wing PAANG... 300 Tanker Rd....... Moon Township....... PA 15108 Air Force 3010 19A...
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2011-03-10
... Malinowski, Southeast Regional Office, NMFS, 263 13th Avenue, South, St. Petersburg, FL 33701. Instructions... INFORMATION CONTACT: Rich Malinowski, 727-824-5305; fax: 727-824-5308. SUPPLEMENTARY INFORMATION: The reef...
Reevaluation of tsunami formation by debris avalanche at Augustine Volcano, Alaska
Waythomas, C.F.
2000-01-01
Debris avalanches entering the sea at Augustine Volcano, Alaska have been proposed as a mechanism for generating tsunamis. Historical accounts of the 1883 eruption of the volcano describe 6- to 9-meter-high waves that struck the coastline at English Bay (Nanwalek), Alaska about 80 kilometers east of Augustine Island. These accounts are often cited as proof that volcanigenic tsunamis from Augustine Volcano are significant hazards to the coastal zone of lower Cook Inlet. This claim is disputed because deposits of unequivocal tsunami origin are not evident at more than 50 sites along the lower Cook Inlet coastline where they might be preserved. Shallow water (<25 m) around Augustine Island, in the run-out zone for debris avalanches, limits the size of an avalanche-caused wave. If the two most recent debris avalanches, Burr Point (A.D. 1883) and West Island (<500 yr. B.P.) were traveling at velocities in the range of 50 to 100 meters per second, the kinetic energy of the avalanches at the point of impact with the ocean would have been between 1014 and 1015 joules. Although some of this energy would be dissipated through boundary interactions and momentum transfer between the avalanche and the sea, the initial wave should have possessed sufficient kinetic energy to do geomorphic work (erosion, sediment transport, formation of wave-cut features) on the coastline of lowwer Cook Inlet. Because widespread evidence of the effects of large waves cannot be found, it appears that the debris avalanches could not have been traveling very fast when they entered the sea, or they happened during low tide and displaced only small volumes of water. In light of these results, the hazard from volcanigenic tsunamis from Augustine Volcano appears minor, unless a very large debris avalanche occurs at high tide.
Confirmation and calibration of computer modeling of tsunamis produced by Augustine volcano, Alaska
Beget, James E.; Kowalik, Zygmunt
2006-01-01
Numerical modeling has been used to calculate the characteristics of a tsunami generated by a landslide into Cook Inlet from Augustine Volcano. The modeling predicts travel times of ca. 50-75 minutes to the nearest populated areas, and indicates that significant wave amplification occurs near Mt. Iliamna on the western side of Cook Inlet, and near the Nanwelak and the Homer-Anchor Point areas on the east side of Cook Inlet. Augustine volcano last produced a tsunami during an eruption in 1883, and field evidence of the extent and height of the 1883 tsunamis can be used to test and constrain the results of the computer modeling. Tsunami deposits on Augustine Island indicate waves near the landslide source were more than 19 m high, while 1883 tsunami deposits in distal sites record waves 6-8 m high. Paleotsunami deposits were found at sites along the coast near Mt. Iliamna, Nanwelak, and Homer, consistent with numerical modeling indicating significant tsunami wave amplification occurs in these areas.
Doukas, Michael P.
1995-01-01
Airborne sulfur dioxide (SO2) gas sampling of the Cook Inlet volcanoes (Mt. Spurr, Redoubt, Iliamna, and Augustine) began in 1986 when several measurements were carried out at Augustine volcano during the eruption of 1986 (Rose and others, 1988). More systematic monitoring for SO2 began in March 1990 and for carbon dioxide (CO2) began in June, 1990 at Redoubt Volcano (Brantley, 1990 and Casadevall and others, 1994) and continues to the present. This report contains all of the available daily SO2 and CO2 emission rates determined by the U.S. Geological Survey (USGS) from March 1990 through July 1994. Intermittent measurements (four to six month intervals) at Augustine and Iliamna began in 1990 and continues to the present. Intermittent measurements began at Mt. Spurr volcano in 1991, and were continued at more regular intervals from June, 1992 through the 1992 eruption at the Crater Peak vent to the present.
77 FR 37672 - Environmental Impacts Statements; Notice of Availability
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-22
... EIS, NOAA, AS, Fagatele Bay National Marine Sanctuary Management Plan, Implementation, Tutuila Island.... 20120195, Draft EIS, NPS, FL, Fort Matanzas National Monument General Management Plan, Implementation, St... filing documents online and providing feedback on the process. To participate in the pilot, register at...
75 FR 51284 - Receipt of Applications for Permit
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2010-08-19
... Service Director. III. Permit Applications Endangered Species Applicant: Schubot Exotic Bird Health Center... obtained from 20-50 day old nestlings, Abaco parrot (Amazona leucocephala bahamensis), for the purpose of... Marine Mammals and Marine Mammals Applicant: EcoHealth Alliance, Inc., St. Petersburg, FL; PRT-107933 The...
2009-07-30
CAPE CANAVERAL, Fla. – – Photographers and spectators show their interest in the Augustine Commission, meeting in Cocoa Beach, Fla. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Jim Grossmann
2009-07-30
CAPE CANAVERAL, Fla. – Photographers and spectators show their interest in the Augustine Commission, meeting in Cocoa Beach, Fla. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Jim Grossmann
2009-07-30
CAPE CANAVERAL, Fla. – Photographers and spectators show their interest in the Augustine Commission, meeting in Cocoa Beach, Fla. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Jim Grossmann
2009-07-30
CAPE CANAVERAL, Fla. – Media representatives and the public are gathered in the Hilton Hotel in Cocoa Beach, Fla., to question the Augustine Commission meeting there. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Kim Shiflett
76 FR 34072 - Environmental Impacts Statements; Notice of Availability
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-10
.... 20110178, Draft EIS, NRC, FL, Generic--License Renewal of Nuclear Plants Regarding Crystal River Unit 3.... 20110182, Final EIS, WAPA, CA, Rice Solar Energy Project, Proposed 150 megawatt Solar Energy Generating..., Access, Wildlife, Fisheries, Soil and Water, Idaho Panhandle National Forest, St. Joe Ranger District...
77 FR 21559 - Ocean Transportation Intermediary License; Applicants
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-10
.... Global Distribution & Logistics LLC (NVO & OFF), 7977 NW 21st Street, Miami, FL 33122. Officers: Jose L.../ Treasurer. Application Type: New NVO & OFF License. Icon Logistics Services LLC (NVO), 14440 Cherry Lane Ct... Vinusa, President. Application Type: New NVO License. Javelin Logistics Corporation (NVO & OFF), 7447...
Augustine and the Liberal Arts
ERIC Educational Resources Information Center
Kenyon, Erik
2013-01-01
In an early dialogue, "On Order", Augustine sets out a program for thinking about thinking. Through such reflections, students attain self-knowledge and prepare for philosophical inquiry. The liberal arts are useful for this project, insofar as they provide opportunities for thinking, yet they are not ultimately necessary. I suggest that "On…
Volcanic Processes and Geology of Augustine Volcano, Alaska
Waitt, Richard B.; Beget, James E.
2009-01-01
Augustine Island (volcano) in lower Cook Inlet, Alaska, has erupted repeatedly in late-Holocene and historical times. Eruptions typically beget high-energy volcanic processes. Most notable are bouldery debris avalanches containing immense angular clasts shed from summit domes. Coarse deposits of these avalanches form much of Augustine's lower flanks. A new geologic map at 1:25,000 scale depicts these deposits, these processes. We correlate deposits by tephra layers calibrated by many radiocarbon dates. Augustine Volcano began erupting on the flank of a small island of Jurassic clastic-sedimentary rock before the late Wisconsin glaciation (late Pleistocene). The oldest known effusions ranged from olivine basalt explosively propelled by steam, to highly explosive magmatic eruptions of dacite or rhyodacite shed as pumice flows. Late Wisconsin piedmont glaciers issuing from the mountainous western mainland surrounded the island while dacitic eruptive debris swept down the south volcano flank. Evidence is scant for eruptions between the late Wisconsin and about 2,200 yr B.P. On a few south-flank inliers, thick stratigraphically low pumiceous pyroclastic-flow and fall deposits probably represent this period from which we have no radiocarbon dates on Augustine Island. Eruptions between about 5,350 and 2,200 yr B.P. we know with certainty by distal tephras. On Shuyak Island 100 km southeast of Augustine, two distal fall ashes of Augustinian chemical provenance (microprobe analysis of glass) date respectively between about 5,330 and 5,020 yr B.P. and between about 3,620 and 3,360 yr B.P. An Augustine ash along Kamishak Creek 70 km southwest of Augustine dates between about 3,850 and 3,660 yr B.P. A probably Augustinian ash lying within peat near Homer dates to about 2,275 yr B.P. From before 2,200 yr B.P. to the present, Augustine eruptive products abundantly mantle the island. During this period, numerous coarse debris avalanches swept beyond Augustine's coast, most recently in A.D. 1883. The decapitated summit after the 1883 eruption, replaced by andesite domes of six eruptions since, shows a general process: collapse of steep summit domes, then the summit regrown by later dome eruptions. The island's stratigraphy is based on six or seven coarse-pumice tephra 'marker beds'. In upward succession they are layers G (2,100 yr B.P.), I (1,700 yr B.P.), H (1,400 yr B.P.), C (1,200-1,000 yr B.P.), M (750 yr B.P.), and B (390 yr B.P.). A coarse, hummocky debris-avalanche deposit older than about 2,100 yr B.P. - or perhaps a stack of three of them - lies along the east coast, the oldest exposed such bouldery diamicts on Augustine Island. Two large debris avalanches swept east and southeast into the sea between about 2,100 and 1,800 yr B.P. A large debris avalanche shed east and east-northeast into the sea between 1,700 and 14,00 yr B.P. Between about 1,400 and 1,100 yr B.P. debris avalanches swept into the sea on the volcano's south, southwest, and north-northwest. Pumiceous pyroclastic fans spread to the southeast and southwest, lithic pyroclastic flows and lahars (?) to the south and southeast. Pyroclastic flows, pyroclastic surges, and lahars swept down the west and south flanks between about 1,000 and 750 yr B.P. A debris avalanche swept into the sea on the west, and a small one on the south-southeast, between about 750 and 400 yr B.P. Large lithic pyroclastic flows shed to the southeast; smaller ones descended existing swales on the southwest and south. Between about 400 yr B.P. and historical time (late 1770s), three debris avalanches swept into the sea on the west-northwest, north-northwest, and north flanks. One of them (West Island) was large and fast: most of it rode to sea far beyond a former sea cliff, and its surface includes geomorphic evidence of having initiating a tsunami. Augustine's only conspicuous lava flow erupted on the north flank. During this prehistoric period numerous domes grew at th
2009-07-30
CAPE CANAVERAL, Fla. – Phil McAlister, special assistant for Program Analysis in NASA's Office of Program Analysis and Evaluation, introduces the Augustine Commission, meeting in Cocoa Beach, Fla. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Jim Grossmann
2009-07-30
CAPE CANAVERAL, Fla. – Bohdan Bejmuk, chair of Constellation Program Standing Review Board, is seated at the conference table for the introduces the Augustine Commission, meeting in Cocoa Beach, Fla. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Jim Grossmann
2009-07-30
CAPE CANAVERAL, Fla. – Spectators interested in the future of the Space Program discuss statements made during the public meeting of the Augustine Commission in Cocoa Beach, Fla. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Jim Grossmann
2009-07-30
CAPE CANAVERAL, Fla. – Dr. Christopher Chyba, professor of Astrophysical Sciences and International Affairs at Princeton University, speaks during the Augustine Commission, meeting in Cocoa Beach, Fla. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Jim Grossmann
Ecological Responses to Pollution Abatement: A Framework for Measurement and Assessment for Coastal Ecosystems (Abstract). To be presented at the 16th Biennial Conference of the Estuarine Research Foundation, ERF 2001: An Estuarine Odyssey, 4-8 November 2001, St. Pete Beach, FL. ...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-15
... island history and ecosystem as they relate to the coastal environment, and management style... management boundary of approximately 12,490 acres. The staff oversees 21 Farm Service Agency easements... management, conservation, legal mandates, and our policies. In addition to outlining broad management...
77 FR 38288 - Ocean Transportation Intermediary License; Applicants
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-27
...). Application Type: Name Change. Global Atlantic Logistics LLC (OFF), 1901 SW 31st Avenue, Pembroke Park, FL....gov . Bellcom, Inc. (NVO), 503 Commerce Park Drive, Suite E, Marietta, GA 30060. Officers: Cornelius U... License. Benchmark Worldwide Logistics, Inc. dba Star Ocean Lines (NVO & OFF), 24900 South Route 53...
Energy Analysis Research Staff | Energy Analysis | NREL
303-275-3725 Augustine, Chad Researcher V-Systems Engineering Chad.Augustine@nrel.gov 303-384-7382 Researcher IV-Model Engineering Clayton.Barrows@nrel.gov 303-275-3921 Beiter, Philipp Energy Markets and Engineering Gregory.Brinkman@nrel.gov 303-384-7390 Brodt-Giles, Deborah Group Manager III-Data Science
Augustine and Education in Critical Thinking
ERIC Educational Resources Information Center
Puolimatka, Tapio
2005-01-01
Augustine's concept of the deep self provides a basis for a complex and many-faceted account of critical thinking. He uncovers the moral sources of thinking in the inner depths of the self and shows that critical thinking presupposes radical self-reflection ready to face the truth about oneself. Self-knowledge assumes transparency, consciousness…
1981-04-01
Facilities EngineerATTN: DAEN-MPC Fitzs ;mons Amy Medical Center ATTN: DAEN-PE Army Instl. and Major Activities (CONuS; waiter Reed Army Medical center ATTN...S)St. Paul Fort Sheridan 21st Support ComandTulsa Fort Stewart4 Vicksburg Fort Wainmright AN: AREA (5) Walls Walla Vancouver Bks. Wilmington US Am...ABG/DEEE Patrick AFB, FL 32925 ATTN: XRQ ’ C Bandy, John T. The Solutions Data Base component of the Water Pollution Abatement Subsystem (WPAS) of the
Modeling Fluid-Structure Interaction in ANSYS Workbench
2016-08-31
IB U TI O N S TA TE M EN T A .A pp ro ve d fo rp ub lic re le as e; di st rib...Q R M Si er ra L ob o, In c. M od el in g Fl ui d- St ru ct ur e In te ra ct io n in A N SY S W or kb en ch 31 A ug us t 2 01 6 2 D IS TR IB ...S) G ro up 3 D IS TR IB U TI O N S TA TE M EN T A .A pp ro ve d fo rp ub lic re le as e; di st rib
A Study on the Significance of Spiritual Learning and Teaching through Augustine's "Confessions"
ERIC Educational Resources Information Center
Shim, Seung-hwan
2017-01-01
This study will examine the significance of spirituality and how to cultivate it in this modern era, in which introspection on the meaning of life is lacking due to issues including consumerism, violence, terror, hedonism, and the influences of an instrumental education environment, through Augustine's "Confessions." This study suggests…
2009-07-30
CAPE CANAVERAL, Fla. – Members of the Augustine Commission are meeting in Cocoa Beach, Fla. At left is Chairman Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., and, at right, is Phil McAlister, special assistant for Program Analysis in NASA's Office of Program Analysis and Evaluation. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. The committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Kim Shiflett
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-02
... include: (1) The control of invasive exotic species combined with education; (2) the need for more... habitats, or improve wildlife and public use management programs. Species of Federal responsibility, such as threatened and endangered species and migratory birds, would continue to be monitored at present...
47 CFR 90.631 - Trunked systems loading, construction and authorization requirements.
Code of Federal Regulations, 2011 CFR
2011-10-01
... authorization requirements. (a) Non-SMR trunked systems will be authorized on the basis of a loading criteria of... minimum of seventy (70) mobiles for each channel authorized will be placed into operation within five (5...; Washington, DC; Dallas-Fort Worth, TX; Miami, FL; Cleveland, OH; St. Louis, MO; Atlanta, GA; Pittsburgh, PA...
47 CFR 90.631 - Trunked systems loading, construction and authorization requirements.
Code of Federal Regulations, 2014 CFR
2014-10-01
... authorization requirements. (a) Non-SMR trunked systems will be authorized on the basis of a loading criteria of... minimum of seventy (70) mobiles for each channel authorized will be placed into operation within five (5..., TX; Washington, DC; Dallas-Fort Worth, TX; Miami, FL; Cleveland, OH; St. Louis, MO; Atlanta, GA...
47 CFR 90.631 - Trunked systems loading, construction and authorization requirements.
Code of Federal Regulations, 2013 CFR
2013-10-01
... authorization requirements. (a) Non-SMR trunked systems will be authorized on the basis of a loading criteria of... minimum of seventy (70) mobiles for each channel authorized will be placed into operation within five (5..., TX; Washington, DC; Dallas-Fort Worth, TX; Miami, FL; Cleveland, OH; St. Louis, MO; Atlanta, GA...
TOP DOWN CONTROL OF THE MICROBIAL LOOP IN ESTUARINE PHYTOPLANKTON
Top Down Control of the Microbial Loop in Estuarine Plankton (Abstract). To be presented at the 16th Biennial Conference of the Estuarine Research Foundation, ERF 2001: An Estuarine Odyssey, 4-8 November 2001, St. Pete Beach, FL. 1 p. (ERL,GB R846).
We examined the effects...
Responses of volatile compounds in inner tissues on refrigeration in full ripe tomatoes
USDA-ARS?s Scientific Manuscript database
A 4-day storage of tomato fruit in refrigerator, a common consumer practice in kitchens, which is not recommended though, would significant suppress the volatile production in pericarp; however, little is reported on volatile profile in inner tissues. In this study, red “FL 47” tomato fruits were st...
TOXICITY OF CLAY FLOCCULATION OF RED TIDE ORGANISMS ON BENTHIC ORGANISMS ERF 2001
Toxicity of Clay Flocculation of Red Tide Organisms on Benthic Organisms (Abstract). To be presented at the16th Biennial Conference of the Estuarine Research Foundation, ERF 2001: An Estuarine Odyssey, 4-8 November 2001, St. Pete Beach, FL. 1 p. (ERL,GB R854).
We have eva...
Who is missing the message? Targeting strategies to increase food label use among US adults
USDA-ARS?s Scientific Manuscript database
Objective: To evaluate the associations between sociodemographic and psychosocial characteristics and food label (FL) use in US adults. Design: The 1994-1996 Continuing Survey of Food Intakes by Individuals and the Diet and Health Knowledge Survey for 2,797 US adults were used. High socioeconomic st...
NASA Astrophysics Data System (ADS)
Fernandez, J. C.; Shrestha, R. L.; Carter, W. E.; Slatton, C. K.; Singhania, A.
2006-12-01
The UF GEM Research Center is working towards developing a Mobile Terrestrial Laser Scanning System (M- TLSS). The core of the M-TLSS is a commercial 2-axis ground based laser scanner, Optech ILRIS-36D, which is capable of generating XYZ with laser intensity or RGB textured point clouds in a range from 3m to 1500m. The laser operates at a wavelength of 1535 nm. The sample separation can be adjusted down to 0.00115°, and the scanning speed is 2,000 points per second. The scanner is integrated to a mobile telescoping, rotating and tilting platform which is essentially a telescopic lift mounted on the back of a pick up truck. This provides up to 6 degrees of freedom for performing scanning operations. A scanner built-in 6 megapixel digital camera and a digital video camera provide the M-TLSS moving and still imagining capability. The applications of the M-TLSS data sets are numerous in both the fields of science and engineering. This paper will focus on the application of M-TLSS as a complement to ALSM in the study of beach morphology in the St. Augustine, Florida area. ALSM data covers a long stretch of beach with a moderate sample density of approximately 1 laser return per square meter, which enables the detection of submeter-scale changes in shoreline position and dune heights over periods of few months. The M-TLSS, on the other hand, can provide high density point clouds (centimeter scale point spacing) of smaller areas known to be highly prone to erosion. From these point clouds centimeter level surface grids are created. These grids will be compared with the ALSM data and with a time series of M-TLSS data over the same area to provide high resolution, short term beach erosion monitoring. Surface morphological parameters that will be compared among the ALSM and M-TLSS data sets include shoreline position and gradients and standard deviations of elevations on cross- shore transects.
Infrasonic array observations at I53US of the 2006 Augustine Volcano eruptions
Wilson, C.R.; Olson, J.V.; Szuberla, Curt A.L.; McNutt, Steve; Tytgat, Guy; Drob, Douglas P.
2006-01-01
The recent January 2006 Augustine eruptions, from the 11th to the 28th, have produced a series of 12 infrasonic signals that were observed at the I53US array at UAF. the eruption times for the signals were provided by the Alaska Volcanic Observatory at UAF using seismic sensors and a Chaparral microphone that are installed on Augustine Island. The bearing and distance of Augustine from I53US are, respectively, 207.8 degrees and 675 km. The analysis of the signals is done with a least-squares detector/estimator that calculates, from the 28 different sensor-pairs in the array, the mean of the cross-correlation maxima (MCCM), the horizontal trace-velocity and the azimuth of arrival of the signal using a sliding-window of 2000 data points. The data were bandpass filtered from 0.03 to 0.10 Hz. The data are digitized at a rate of 20 Hz. The average values of the signal parameters for all 12 Augustine signals are as follows: MCCM=0.85 (std 0.14), Trace-velocity=0.346 (std 0.016) km/sec, Azimuth=209 (std 2) deg. The celerity for each signal was calculated using the range 675 km and the individual travel times to I53US. The average celerity for all ten eruption signals was 0.27 (std 0.02) km/sec. Ray tracing studies, using mean values of the wind speed and temperature profiles (along the path) from NRL, have shown that there was propagation to I53US by both stratospheric and thermospheric ray paths from the volcano.
Tsunami Warning Protocol for Eruptions of Augustine Volcano, Cook Inlet, Alaska
NASA Astrophysics Data System (ADS)
Whitmore, P.; Neal, C.; Nyland, D.; Murray, T.; Power, J.
2006-12-01
Augustine is an island volcano that has generated at least one tsunami. During its January 2006 eruption coastal residents of lower Cook Inlet became concerned about tsunami potential. To address this concern, NOAA's West Coast/ Alaska Tsunami Warning Center (WC/ATWC) and the Alaska Volcano Observatory (AVO) jointly developed a tsunami warning protocol for the most likely scenario for tsunami generation at Augustine: a debris avalanche into the Cook Inlet. Tsunami modeling indicates that a wave generated at Augustine volcano could reach coastal communities in approximately 55 minutes. If a shallow seismic event with magnitude greater than 4.5 occurred near Augustine and the AVO had set the level of concern color code to orange or red, the WC/ATWC would immediately issue a warning for the lower Cook Inlet. Given the short tsunami travel times involved, potentially affected communities would be provided as much lead time as possible. Large debris avalanches that could trigger a tsunami in lower Cook Inlet are expected to be accompanied by a strong seismic signal. Seismograms produced by these debris avalanches have unique spectral characteristics. After issuing a warning, the WC/ATWC would compare the observed waveform with known debris avalanches, and would consult with AVO to further evaluate the event using AVO's on-island networks (web cameras, seismic network, etc) to refine or cancel the warning. After the 2006 eruptive phase ended, WC/ATWC, with support from AVO and the University of Alaska Tsunami Warning and Environmental Observatory for Alaska program (TWEAK), developed and installed "splash-gauges" which will provide confirmation of tsunami generation.
Corneal topography with an aberrometry-topography system.
Mülhaupt, Michael; Dietzko, Sven; Wolffsohn, James; Bandlitz, Stefan
2018-05-07
To investigate the agreement between the central corneal radii and corneal eccentricity measurements generated by the new Wave Analyzer 700 Medica (WAV) compared to the Keratograph 4 (KER) and to test the repeatability of the instruments. 20 subjects (10 male, mean age 29.1 years, range 21-50 years) were recruited from the students and staff of the Cologne School of Optometry. Central corneal radii for the flat (r c/fl ) and steep (r c/st ) meridian as well as corneal eccentricity for the nasal (e nas ), temporal (e temp ), inferior (e inf ) and superior (e sup ) directions were measured using WAV and KER by one examiner in a randomized order. Central radii of the flat (r c/fl ) and steep (r c/st ) meridian measured with both instruments were statically significantly correlated (r = 0.945 and r = 0.951; p < 0.001). Comparison between the WAV and KER showed that r c/fl and r c/st measured with WAV were significantly steeper than those measured with KER (p < 0.001). Corneal eccentricities were statistically significantly correlated in all meridians (p < 0.05). Compared to KER, e temp and e sup measured with WAV were greater (p < 0.05), while there were no statistically significant differences for e nas and e inf (p = 0.350 and p = 0.083). For the central radii, repeated measurements were not significantly different for the KER or WAV (p > 0.05). Limits of agreement (LoA) indicate a better repeatability for the KER compared to WAV. Corneal topography measurements captured with the WAV were strongly correlated with the KER. However, due to the differences in measured corneal radii and eccentricities, the devices cannot be used interchangeably. For corneal topography the KER demonstrated better repeatability. Copyright © 2018 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.
ERIC Educational Resources Information Center
Peng, Chengzhi
2013-01-01
Funded by the UK JISC Institutional Innovation Programme, the Augustine House Experiment sets out to investigate how the location sensing data collected over students' uses of the iBorrow notebooks can be visualised to reveal aspects of the new learning landscape during a 1-week sensing period. Indoor real-time location sensing technologies are…
Socrates, Augustine, and Paul Gauguin on the Reciprocity between Speech and Silence in Education
ERIC Educational Resources Information Center
Caranfa, Angelo
2013-01-01
While most educational practices today place an excessive amount of attention on discourse, this article attaches great importance to the reciprocity between speech and silence by drawing from the writings of Plato's Socrates, Augustine, and Paul Gauguin for whom this reciprocity is of the essence in learning. These three figures teach that…
2009-07-30
CAPE CANAVERAL, Fla. – Members of the Augustine Commission are meeting in Cocoa Beach, Fla. From left are Dr. Christopher Chyba, Professor of Astrophysical Sciences and international Affairs at Princeton University; Jeff Greason, co-founder and CEO of XCOR Aerospace; and Bohdan Bejmuk, chair of Constellation Program Standing Review Board. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Kim Shiflett
USDA-ARS?s Scientific Manuscript database
Knowledge of daily activity patterns in adult mosquitoes can be used to determine the best time to apply adulticides for mosquito control. Many factors influence these activity patterns, including migration, hormonal cycles in the mosquito, hunger, and the need to lay eggs. In this study, FL scien...
11. Photocopy of photograph, U.S. Army, ca. 1943 (original print ...
11. Photocopy of photograph, U.S. Army, ca. 1943 (original print located at Rocky Mountain Arsenal, Commerce City, Colorado). R.M.A. - 243 - COMPRESSOR BLDG. 1st FL. LOOKING N.W. - Rocky Mountain Arsenal, Chlorine Production Cell Building, 405 feet South of December Seventh Avenue; 330 feet West of D Street, Commerce City, Adams County, CO
4. Photocopy of photograph, U.S. Army, ca. 1943 (original print ...
4. Photocopy of photograph, U.S. Army, ca. 1943 (original print located at Rocky Mountain Arsenal, Commerce City, Colorado). R.M.A. - 471 - REACTION BLDG. 1st FL. - Rocky Mountain Arsenal, Thionyl Chloride Reaction-Drum Loading Building, 1190 feet South of December Seventh Avenue; 1070 feet East of D Street, Commerce City, Adams County, CO
7. Photocopy of photograph, U.S. Army, ca. 1943 (original print ...
7. Photocopy of photograph, U.S. Army, ca. 1943 (original print located at Rocky Mountain Arsenal, Commerce City, Colorado). R.M.A. - 325 - POWER PLANT 1st FL. LOOKING EAST. - Rocky Mountain Arsenal, Electric Power Plant, 1022 feet South of December Seventh Avenue; 280 feet West of D Street, Commerce City, Adams County, CO
4. Photocopy of photograph, U.S. Army, ca. 1943 (original print ...
4. Photocopy of photograph, U.S. Army, ca. 1943 (original print located at Rocky Mountain Arsenal, Commerce City, Colorado). R.M.A. - 111 - ADMIN. BLDG. 1st FL. HALL LOOKING EAST. - Rocky Mountain Arsenal, Administration Building, 400 feet North of December Seventh Avenue; 1940 feet East of C Street, Commerce City, Adams County, CO
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-07
... would determine the size, seasonality, and frequency of prescribed fires to benefit rail species. We... response. We would work to restore the hydrologic setting to benefit marsh birds and determine the role of..., cattle grazing, and/ or other forms of vegetation maintenance to benefit this species on the Bee Line...
31 CFR 100.17 - Location of Federal Reserve banks and branches.
Code of Federal Regulations, 2010 CFR
2010-07-01
...), Miami, FL 33152 Nashville Branch—301 Eighth Avenue, North, Nashville, TN 37203 New Orleans Branch—525 St. Charles Avenue (P.O. Box 61630), New Orleans, LA 70161 Chicago—230 South LaSalle Street (P.O. Box 834... branches. Federal Reserve Bank and Address Boston—600 Atlantic Avenue, Boston, MA 02106 New York—33 Liberty...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-25
... Malinowski, Southeast Regional Office, NMFS, 263 13th Avenue South, St. Petersburg, FL 33701. Instructions... . FOR FURTHER INFORMATION CONTACT: Rich Malinowski, Southeast Regional Office, NMFS, telephone 727-824-5305; email: rich.malinowski@noaa.gov . SUPPLEMENTARY INFORMATION: The reef fish fishery of the Gulf of...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-19
... be obtained from Rich Malinowski, NMFS, Southeast Regional Office, 263 13th Avenue South, St. Petersburg, FL 33701; telephone: 727-824-5305. FOR FURTHER INFORMATION CONTACT: Rich Malinowski, telephone: 727-824- 5305, e-mail Rich.Malinowski@noaa.gov . SUPPLEMENTARY INFORMATION: The reef fish fishery of...
Analysis of Defense Industry Consolidation Effects on Program Acquisition Costs
2007-12-01
overhead costs. Also in 1993, Norman R. Augustine, then CEO of Lockheed Martin, headed an effort involving other major defense industry executives...name programs, Lockheed Chairman Norman Augustine could only name one (Pearlstein, 14 July 1997). A GAO study looked into one method that...latest technology could, essential, resort to monopolistic practices of market and cost control. Kovacic and Smallwood , in an analysis of defense
Numerical simulation of tsunami generation by cold volcanic mass flows at Augustine Volcano, Alaska
Waythomas, C.F.; Watts, P.; Walder, J.S.
2006-01-01
Many of the world's active volcanoes are situated on or near coastlines. During eruptions, diverse geophysical mass flows, including pyroclastic flows, debris avalanches, and lahars, can deliver large volumes of unconsolidated debris to the ocean in a short period of time and thereby generate tsunamis. Deposits of both hot and cold volcanic mass flows produced by eruptions of Aleutian arc volcanoes are exposed at many locations along the coastlines of the Bering Sea, North Pacific Ocean, and Cook Inlet, indicating that the flows entered the sea and in some cases may have initiated tsunamis. We evaluate the process of tsunami generation by cold granular subaerial volcanic mass flows using examples from Augustine Volcano in southern Cook Inlet. Augustine Volcano is the most historically active volcano in the Cook Inlet region, and future eruptions, should they lead to debris-avalanche formation and tsunami generation, could be hazardous to some coastal areas. Geological investigations at Augustine Volcano suggest that as many as 12-14 debris avalanches have reached the sea in the last 2000 years, and a debris avalanche emplaced during an A.D. 1883 eruption may have initiated a tsunami that was observed about 80 km east of the volcano at the village of English Bay (Nanwalek) on the coast of the southern Kenai Peninsula. Numerical simulation of mass-flow motion, tsunami generation, propagation, and inundation for Augustine Volcano indicate only modest wave generation by volcanic mass flows and localized wave effects. However, for east-directed mass flows entering Cook Inlet, tsunamis are capable of reaching the more populated coastlines of the southwestern Kenai Peninsula, where maximum water amplitudes of several meters are possible.
NASA Astrophysics Data System (ADS)
Rath, C. A.; Browne, B. L.
2011-12-01
Augustine Volcano (Alaska) is the most active volcano in the eastern Aleutian Islands, with 6 violent eruptions over the past 200 years and at least 12 catastrophic debris-avalanche deposits over the past ~2,000 years. The frequency and destructive nature of these eruptions combined with the proximity of Augustine Volcano to commercial ports and populated areas represents a significant hazard to the Cook Inlet region of Alaska. The focus of this study examines the relationship between debris-avalanche events and the subsequent emplacement of pyroclastic density currents by comparing the stratigraphic, granulometric, and petrographic characteristics of pyroclastic deposits emplaced following the 1883 A.D. Burr Point debris-avalanche and those emplaced following the ~370 14C yr B.P. West Island debris-avalanche. Data from this study combines grain size and componentry analysis of pyroclastic deposits with density, textural, and compositional analysis of juvenile clasts contained in the pyroclastic deposits. The 1883 A.D. Burr Point pyroclastic unit immediately overlies the 1883 debris avalanche deposit and underlies the 1912 Katmai ash. It ranges in thickness from 4 to 48 cm and consists of fine to medium sand-sized particles and coarser fragments of andesite. In places, this unit is normally graded and exhibits cross-bedding. Many of these samples are fines-enriched, with sorting coefficients ranging from -0.1 to 1.9 and median grain size ranging from 0.1 to 2.4 mm. The ~370 14C yr B.P. West Island pyroclastic unit is sandwiched between the underlying West Island debris-avalanche deposit and the overlying 1912 Katmai Ash deposit, and at times a fine-grained gray ash originating from the 1883 eruption. West Island pyroclastic deposit is sand to coarse-sand-sized and either normally graded or massive with sorting coefficients ranging from 0.9 to 2.8 and median grain sizes ranging from 0.4 to 2.6 mm. Some samples display a bimodal distribution of grain sizes, while most display a fines-depleted distribution. Juvenile andesite clasts exist as either subrounded to subangular fragments with abundant vesicles that range in color from white to brown or dense clasts characterized by their porphyritic and glassy texture. Samples from neither eruption correlate in sorting or grain size with distance from the vent. Stratigraphic and granulometric data suggest differences in the manner in which these two pyroclastic density currents traveled and groundmass textures are interpreted as recording differences in how the two magmas ascended and erupted, whereas juvenile Burr Point clasts resemble other lava flows erupted from Augustine Volcano, vesicular and glassy juvenile West Island clasts bear resemblance to clasts derived from so-called "blast-generated" pyroclastic density deposits at Mt. St. Helens in 1980 and Bezymianny in 1956.
Lee, Chang-Wook; Lu, Zhong; Kwoun, Oh-Ig; Won, Joong-Sun
2008-01-01
The Augustine Volcano is a conical-shaped, active stratovolcano located on an island of the same name in Cook Inlet, about 290 km southwest of Anchorage, Alaska. Augustine has experienced seven significant explosive eruptions - in 1812, 1883, 1908, 1935, 1963, 1976, 1986, and in January 2006. To measure the ground surface deformation of the Augustine Volcano before the 2006 eruption, we applied satellite radar interferometry using Synthetic Aperture Radar (SAR) images from three descending and three ascending satellite tracks acquired by European Remote Sensing Satellite (ERS) 1 and 2 and the Environment Satellite (ENVISAT). Multiple interferograms were stacked to reduce artifacts caused by atmospheric conditions, and we used a singular value decomposition method to retrieve the temporal deformation history from several points on the island. Interferograms during 1992 and 2005 show a subsidence of about 1-3 cm/year, caused by the contraction of pyroclastic flow deposits from the 1986 eruption. Subsidence has decreased exponentially with time. Multiple interferograms between 1992 and 2005 show no significant inflation around the volcano before the 2006 eruption. The lack of a pre-eruption deformation signal suggests that the deformation signal from 1992 to August 2005 must have been very small and may have been obscured by atmospheric delay artifacts.
10. Photocopy of photograph, U.S. Army, ca. 1943 (original print ...
10. Photocopy of photograph, U.S. Army, ca. 1943 (original print located at Rocky Mountain Arsenal, Commerce City, Colorado). R.M.A. - 321 - BOILER HOUSE 1st FL. - LOOKING EAST. - Rocky Mountain Arsenal, Boiler Plant-Central Gas Heat Plant, 1022 feet South of December Seventh Avenue; 525 feet West of D Street, Commerce City, Adams County, CO
Wayne Cook; Bret W. Butler
2007-01-01
The 2nd Fire Behavior and Fuels Conference: Fire Environment -- Innovations, Management and Policy was held in Destin, FL, March 26-30, 2007. Following on the success of the 1st Fire Behavior and Fuels Conference, this conference was initiated in response to the needs of the National Wildfire Coordinating Group -- Fire Environment Working Team.
Organo-Soluble Porphyrin Mixed Monolayer-Protected Gold Nanorods with Intercalated Fullerenes
2012-03-16
Mixed Monolayer- Protected Gold Nanorods with Intercalated Fullerenes Chenming Xue, Yongqian Xu, Yi Pang, Dingshan Yu, Liming Dai, Min Gao, Augustine...Protected Gold Nanorods with Intercalated Fullerenes 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT... Fullerenes Chenming Xue, † Yongqian Xu, ‡ Yi Pang, ‡ Dingshan Yu, § Liming Dai, § Min Gao, † Augustine Urbas ± and Quan
Cervelli, P.F.; Fournier, T.; Freymueller, Jeffrey T.; Power, J.A.
2006-01-01
On January 11, 2006 Augustine Volcano erupted after nearly 20 years of quiescence. Global Positioning System (GPS) instrumentation at Augustine, consisting of six continuously recording, telemetered receivers, measured clear precursory deformation consistent with a source of inflation or pressurization beneath the volcano's summit at a depth of around sea level. Deformation began in early summer 2005, and was preceded by a subtle, but distinct, increase in seismicity, which began in May 2005. After remaining more or less constant, deformation rates accelerated on at least three stations beginning in late November 2005. After this date, GPS data suggest the upward propagation of a small dike into the edifice, which, based on the style of deformation and high levels of gas emission, appears to have ascended to shallow levels by mid-December 2005, about four weeks before the eruption began.
Development of a new injury cost scale.
Zeidler, F; Pletschen, B; Scheunert, D; Mattern, B; Alt, B; Miksch, T; Eichendorf, W; Reiss, S
1993-12-01
The Automobile Technique Research Association at Frankfurt, the Institute for Forensic Medicine at Mainz, the Federal Highway Research Institute at Bergisch-Gladbach, the German Motor Vehicle Inspection Association at Stuttgart, and the German Worker's Compensation at St. Augustin have completed a joint research project dealing with injury costs due to automobile accidents. The data for this social cost analysis were based on costs for administrative expenses, medical treatment, rehabilitation measures, social security payment, and loss of income, which were all paid by Worker's Compensation for single, well-documented injuries to the working population in West Germany (15 to 65 years old). The data base used included 15,407 injured and 1,026 fatal road accident victims. Tables are presented which show the costs associated with various injury levels. The result is an injury cost scale (ICS) that might be a base for establishing priorities of safety measures. The ICS has to be seen as supplemental to the AIS.
[Book review] Birds of Malheur National Wildlife Refuge, Oregon
Browning, M. Ralph
1991-01-01
Although John Warham has worked for at least 40 years on procellariids, this book is much more than just a summary of a distinguished research career. It is a useful synthesis of the vast and often obscure literature on the more than 100 species of shearwaters, petrels, albatrosses, and fulmars that comprise the avian order with the widest range of body mass (19.5 g to 8.7 kg) and widest distribution, throughout the world's oceans, from the tropics to open leads in polar ice packs. The order's literary credentials are also impressive, with contributions from Dionysus (200 AD), St. Augustine, and Cole- ridge (not cited). Warham has also unearthed useful references from journals not examined by many ornithologists, such as Bocagiana, Il-Merill, and the Journal of the Manx Museum. He also appears to have done a good job of covering the Japanese-language literature.
Modeling the Impact of Boat Wakes on Living Shoreline Structures in Florida Intracoastal Waters
NASA Astrophysics Data System (ADS)
Herbert, D.; Astrom, E.; Bersoza, A.; Wasman, S.; Angelini, C.; Sheremet, A.
2017-12-01
Increased boating activity has driven morphological and biological changes along the coasts of estuarine environments. Large, recurrent boat wakes impede the growth of oyster reefs and salt marsh vegetation, which both serve as natural protection against erosion. A NOAA-funded experiment along a section of the Intracoastal Waterway at Guana Tolomato Matanzas National Estuarine Research Reserve (GTMNERR) near St. Augustine, Florida, studies the effectiveness of a living shorelines approach in mitigating the erosional impact of high-energy boat wakes. Living shorelines are a natural shoreline stabilization technique, where plants or organic structures are installed on the coastline. This study utilizes a combination of oyster gabions and porous breakwaters to facilitate oyster growth as well as marsh progradation. We present observations of flow and sediment transport associated with boat activity. Numerical simulations are used to evaluate the performance of the breakwaters and their effectiveness in reducing sediment resuspension and transport on the marsh surface.
Medical Robotic and Telesurgical Simulation and Education Research
2013-09-01
Hospital Nicholson Center 601 E Rollins St Orlando, FL 32803 9. SPONSORING / MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S...Principal Investigators: R.M. Satava, University of Washington School of Medicine, Seattle , WA R.D. Smith, Florida Hospital Nicholson Center...Blalock 1210 Baltimore, MD 21287 USA Thomas S . Lendvay, MD, FACS Associate Professor Co-Director, Seattle Children’s Robotics Surgery Center
ERIC Educational Resources Information Center
Day, Philip R., Jr.
Under the auspices of the North American Free Trade Agreement, five states in the United States and six states in Mexico established the Gulf of Mexico Accord to create a working partnership to foster economic development in the Gulf of Mexico. The agreement addresses six major sectors: investment; communication and transportation; health;…
Letters from Augustin Hallerstein, an eighteenth century Jesuit astronomer in Beijing
NASA Astrophysics Data System (ADS)
Juznic, Stanislav
2008-11-01
Augustin Hallerstein (1703-1774) was the last astronomer sent to Beijing by the Society of Jesus. He left Europe for China in his mid-thirties, and continued to send letters back home until he died thirty-five years later. These letters and reports contained important information on Chinese astronomy, and were read in the courts of Europe; many were also published. Hallerstein was one of the most important European astronomers in Beijing, his European publications surpassing those of his predecessors.
Miles, Eleanor; Sheeran, Paschal; Webb, Thomas L
2013-05-01
Augustine and Hemenover (2013) were right to state that meta-analyses should be accurate and generalizable. However, we disagree that our meta-analysis of emotion regulation strategies (Webb, Miles, & Sheeran, 2012) fell short in these respects. Augustine and Hemenover's concerns appear to have accrued from misunderstandings of our inclusion criteria or from disagreements with methodological decisions that are crucial to the validity of meta-analysis. This response clarifies the bases of these decisions and discusses implications for the accuracy and validity of meta-analyses. Furthermore, we show that our findings are consistent with theoretical predictions and previous reviews, and we present new evidence that the effect sizes that we obtained are generalizable. In particular, we demonstrate that our estimates of the effectiveness of emotion regulation strategies reveal how well these strategies predict important emotional outcomes over 1 year. PsycINFO Database Record (c) 2013 APA, all rights reserved.
2009-07-30
CAPE CANAVERAL, Fla. – NASA Kennedy Space Center's Center Director Bob Cabana (right) speaks during the meeting of the Augustine Commission in Cocoa Beach, Fla. At the conference table at left are members of the commission: Dr. Edward F. Crawley, Ford professor of engineering at MIT; General (ret.) Lester L. Lyles, chair of the National Academies Committee on the Rationale and Goals of the U.S. Civil Space Program; and former astronaut Dr. Leroy Chiao, former International Space Station commander and engineering consultant. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Jim Grossmann
NASA Astrophysics Data System (ADS)
Dawson, Phillip B.; Chouet, Bernard A.; Power, John
2011-02-01
Waveform inversions of the very-long-period components of the seismic wavefield produced by an explosive eruption that occurred on 11 January, 2006 at Augustine Volcano, Alaska constrain the seismic source location to near sea level beneath the summit of the volcano. The calculated moment tensors indicate the presence of a volumetric source mechanism. Systematic reconstruction of the source mechanism shows the source consists of a sill intersected by either a sub-vertical east-west trending dike or a sub-vertical pipe and a weak single force. The trend of the dike may be controlled by the east-west trending Augustine-Seldovia arch. The data from the network of broadband sensors is limited to fourteen seismic traces, and synthetic modeling confirms the ability of the network to recover the source mechanism. The synthetic modeling also provides a guide to the expected capability of a broadband network to resolve very-long-period source mechanisms, particularly when confronted with limited observational data.
2009-07-30
CAPE CANAVERAL, Fla. – NASA Kennedy Space Center's Center Director Bob Cabana (right) speaks during the meeting of the Augustine Commission in Cocoa Beach, Fla. At the conference table in the foreground are members of the commission: (from left) Bohdan Bejmuk, chair of Constellation Program Standing Review Board; Jeff Greason, co-founder and CEO of XCOR Aerospace; Dr. Christopher Chyba, professor of Astrophysical Sciences and international Affairs at Princeton University; and Phil McAlister, special assistant for Program Analysis in NASA's Office of Program Analysis and Evaluation. At the request of the Office of Science and Technology Policy, NASA established the Review of U.S. Human Space Flight Plans Committee, known as the Augustine Commission. Chaired by Norman R. Augustine, retired chairman and CEO of Lockheed Martin Corp., the committee is conducting an independent review of ongoing U.S. human spaceflight plans and programs, as well as alternatives, to ensure the nation is pursuing the best trajectory for the future of human space flight - one that is safe, innovative, affordable, and sustainable. Photo credit: NASA/Jim Grossmann
A distal earthquake cluster concurrent with the 2006 explosive eruption of Augustine Volcano, Alaska
Fisher, M.A.; Ruppert, N.A.; White, R.A.; Wilson, Frederic H.; Comer, D.; Sliter, R.W.; Wong, F.L.
2009-01-01
Clustered earthquakes located 25??km northeast of Augustine Volcano began about 6??months before and ceased soon after the volcano's 2006 explosive eruption. This distal seismicity formed a dense cluster less than 5??km across, in map view, and located in depth between 11??km and 16??km. This seismicity was contemporaneous with sharply increased shallow earthquake activity directly below the volcano's vent. Focal mechanisms for five events within the distal cluster show strike-slip fault movement. Cluster seismicity best defines a plane when it is projected onto a northeast-southwest cross section, suggesting that the seismogenic fault strikes northwest. However, two major structural trends intersect near Augustine Volcano, making it difficult to put the seismogenic fault into a regional-geologic context. Specifically, interpretation of marine multichannel seismic-reflection (MCS) data shows reverse faults, directly above the seismicity cluster, that trend northeast, parallel to the regional geologic strike but perpendicular to the fault suggested by the clustered seismicity. The seismogenic fault could be a reactivated basement structure.
The state of the world’s mangroves in the 21st century under climate change
Feller, Ilka C.; Friess, Daniel A.; Krauss, Ken W.; Lewis, Roy R.
2017-01-01
Concerted mangrove research and rehabilitation efforts over the last several decades have prompted a better understanding of the important ecosystem attributes worthy of protection and a better conservation ethic toward mangrove wetlands globally. While mangroves continue to be degraded and lost in specific regions, conservation initiatives, rehabilitation efforts, natural regeneration, and climate range expansion have promoted gains in other areas, ultimately serving to curb the high mangrove habitat loss statistics from the doom and gloom of the 1980s. We highlight those trends in this article and introduce this special issue of Hydrobiologia dedicated to the important and recurring Mangrove and Macrobenthos Meeting. This collection of papers represents studies presented at the fourth such meeting (MMM4) held in St. Augustine, Florida, USA, on July 18–22, 2016. Our intent is to provide a balanced message about the global state of mangrove wetlands by describing recent reductions in net mangrove area losses and highlighting primary research studies presented at MMM4 through a collection of papers. These papers serve not only to highlight on-going global research advancements, but also provide an overview of the vast amount of data on mangrove ecosystem ecology, biology and rehabilitation that emphasizes the uniqueness of the mangrove community.
ERIC Educational Resources Information Center
Simonson, Michael, Ed.
2008-01-01
For the thirty-first year, the Research and Theory Division of the Association for Educational Communications and Technology (AECT) sponsored the publication of these Proceedings. Papers were presented at the annual AECT Convention in Orlando, Florida. This year's Proceedings has two sections--Section 1 includes research and development papers and…
The Role of SIRT1 In Breast Cancer Stem Cells
2016-09-01
CONTRACTING ORGANIZATION: UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER HOUSTON, TX 77030-5400 REPORT DATE: September 2016 TYPE OF REPORT: Final...AND ADDRESS(ES) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER University of Texas Health Science center 7000 Fannin St FL2 Houston, TX...collaboration with Dr. Eva Sevick at the image core center, Institution of Molecular Medicine at UTHSC at Houston. A mammary fat pad cell injection was
Waves in Seagrass Systems: Review and Technical Recommendations
2006-11-01
species (e.g., Halodule wrightii, Thalassia testudinum) are found near the sediment surface while other seagrass species (e.g., Zostera marina, Ruppia...309. Almasi, M. N., C. M. Hoskin, J. K. Reed, and J. Milo. 1987. Effects of natural and artificial Thalassia on rates of sedimentation. Journal of...Florida, St. Petersburg, FL, 123 pp. Koch, E. W. 1994. Hydrodynamics, diffusion boundary layers and photosynthesis of the seagrasses Thalassia testudinum
NASA Astrophysics Data System (ADS)
Penta, C.
2017-12-01
We went to three beaches and took water samples with the plankton net. We measured temperature (air and water), salinity, water transparency and color, and cloud cover. We looked at plankton in the water samples. We went to Bay St. Louis, MS on two different days (2015). We got different plankton on different days. We went to the Lake Pontchartrain Fishing Pier (Slidell, LA) on three different days (2016). We only got some plankton in the samples; most were too small to see with our microscope. There was lots of rain on the third day of sampling, thus there was lots of dirt and less plankton. We went to Pass-a-Grille Beach (St. Pete Beach, FL; 2017) one day and measured everything.
NASA Astrophysics Data System (ADS)
Rison, W.; Krehbiel, P.; Thomas, R.; Edens, H.; Aulich, G.; O'Connor, N.; Kieft, S.; McNutt, S.; Tytgat, G.; Clark, E.
2006-12-01
Following the initial eruptions of Mt. Augustine on January 11-17 2006, we quickly prepared and deployed a first contingent of two portable mapping stations. This was our first use of the newly-developed portable stations, and we were able to deploy them in time to observe the second set of explosive eruptions during the night of January~27-28. The stations were located 17~km apart on the west coast of the Kenai Peninsula, 100~km distant from Augustine on the far western side of Cook Inlet. The stations comprised a minimal network capable of determining the azimuthal direction of VHF radiation sources from electrical discharges, and thus the transverse location of the electrical activity relative to the volcano. The time series data from the southern, Homer station for the initial, energetic explosion at 8:31 pm on January~27 revealed the occurrence of spectacular lightning, which from the two-station data drifted southward from Augustine with time, in the same direction as the plume from the eruption. About 300 distinct lightning discharges occurred over an 11-minute time interval, beginning 2-3~min after the main explosion. The lightning quickly became increasingly complex with time and developed large horizontal extents. One of the final discharges of the sequence lasted 600~ms and had a transverse extent of 15~km, extending to 22~km south of Augustine's summit. In addition to this more usual form of lightning, continuous bursts of radio frequency radiation occurred during the explosion itself, indicating that the tephra was highly charged upon being ejected from the volcano. A completely unplanned and initially missed but one of several fortuitous aspects of the observations was that the Homer station functioned as a 'sea-surface interferometer' whose interference pattern can be used to determine the altitude variation with time for some discharges. The station's VHF antenna was located on the edge of a bluff 210~m above Cook Inlet and received both the direct and reflected signals from the water surface. A clear pattern of interference fringes was observed for the strongest lightning event during the explosive phase and has shown that it was an upward-triggered discharge that propagated upward from Augustine's summit and into the downwind plume. The radiation sources were characteristic of negative polarity breakdown into inferred positive charge in the plume. None of the lightning activity from the January~27-28 eruptions was observed visually due to stormy weather conditions.
Synchronization of Combat Power at the Task Force Level: Defining a Planning Methodology
1989-01-01
tachments) LOCATION SCT ARTY CAS AH SMOKE MORTAR FASCAM TI ME EST ACTUAL. Current Future LD PL 1 X Atk Porn PL 2 PL3 OBJ X PL 1 LD PL 2 FL3 OBJ PL 2 PL 1...learned in medical school to 138 identify the aorta only to arrive at St. Elsewhere, where they call it "the big blue boy .* Right now the US Army has a
Microprocessor Technology for Managers.
1976-05-01
HOURS IS THE APPLICATION OF MICROPROCESSORS TO VIDEO GAMES SUCH AS PING PONG, HANDBALL 1 SPACE WAR GAMES , AND COWBOYS AND INDIANS. MANY MANUFACTURERS OF...MICR OPROCESSOR COMPANIES AEG—T ELEFUNKEN~ 6 FRANKFURT 70, AEG-HOCHHAUS 1 GERMANY . ADAPTIVE SYSTEMS1 P.O . BOX 1481, POMPANO BEACH , FL 33061. -(305...KAWASAKI — CHI , JAPAN . WESTERN DIGITAL , 19242 RED HILL AVE. 1 NEWPORT BEACH I CA 92663. {714) 557-3550. ZILOG, 170 STATE ST., LOS ALTOS 1 CA 94022. {415
Assessing the Biological Weapons and Bioterrorism Threat
2005-12-01
Senate testimony, Dr. Craig Venter suggested that “outbreaks and spread of avian and other fl u virus strains . . . could potentially kill hundreds of...May 23, 2005. 36. Dr. Craig Venter, Testimony to Hearing of the U.S. Senate Committee on Health, Education, Labor and Pensions, “21st Century...International Studies. 241. Robert M. Cook- Deegan , “Issues in Biosecurity and Biosafety,” Science, Vol. 308, No. 5730, June 24, 2005, pp. 1867-1868
Constructing a reference tephrochronology for Augustine Volcano, Alaska
Wallace, Kristi; Coombs, Michelle L.
2013-01-01
Augustine Volcano is the most historically active volcano in Alaska's populous Cook Inlet region. Past on-island work on pre-historic tephra deposits mainly focused on using tephra layers as markers to help distinguish among prevalent debris-avalanche deposits on the island (Waitt and Beget, 2009, USGS Prof Paper 1762), or as source material for petrogenetic studies. No comprehensive reference study of tephra fall from Augustine Volcano previously existed. Numerous workers have identified Holocene-age tephra layers in the region surrounding Augustine Island, but without well-characterized reference deposits, correlation back to the source volcano is difficult. The purpose of this detailed tephra study is to provide a record of eruption frequency and magnitude, as well as to elucidate physical and chemical characteristics for use as reference standards for comparison with regionally distributed Augustine tephra layers. Whole rock major- and trace-element geochemistry, deposit componentry, and field context are used to correlate tephra units on the island where deposits are coarse grained. Major-element glass geochemistry was collected for use in correlating to unknown regional tephra. Due to the small size of the volcanic island (9 by 11 km in diameter) and frequent eruptive activity, on-island exposures of tephra deposits older than a couple thousand years are sparse, and the lettered Tephras B, M, C, H, I, and G of Waitt and Beget (2009) range in age from 370-2200 yrs B.P. There are, however, a few exposures on the south side of the volcano, within about 2 km of the vent, where stratigraphic sections that extend back to the late Pleistocene glaciation include coarse pumice-fall deposits. We have linked the letter-named tephras from the coast to these higher exposures on the south side using physical and chemical characteristics of the deposits. In addition, these exposures preserve at least 5 older major post-glacial eruptions of Augustine. These ultra-proximal sites, along with an off-island section 20 km to the west, provide the first continuous tephrochronology for Augustine that extends from the earliest to latest Holocene. Because examined pumice-fall exposures are limited to a narrow azimuth on the south side of the volcano, the on-island record is likely an incomplete catalog of major eruptions. It is possible however, that the coarse-grained near vent exposures (within 2 km) represent large eruptions that blanketed the entire island in tephra and are representative of the entire Holocene record. The major Holocene tephra units exposed on-island are composed of coarse-grained (cm-scale) pumice ranging in color from white to cream (variably oxidized), and light to medium gray as well as banded varieties. Accidental lithic assembles are highly variable and often unique for individual eruptions. Pumices range from 60-66 wt % SiO2 in whole-rock composition and are distinguishable using trace and minor element abundances and field context. Glass geochemistry is often distinguishable between tephras, but more overlap exists among deposits and presents challenges for correlating to regional tephras.
Roman, Diana C.; Cashman, Katharine V.; Gardner, Cynthia A.; Wallace, Paul J.; Donovan, John J.
2006-01-01
Compositional heterogeneity (56–64 wt% SiO2 whole-rock) in samples of tephra and lava from the 1986 eruption of Augustine Volcano, Alaska, raises questions about the physical nature of magma storage and interaction beneath this young and frequently active volcano. To determine conditions of magma storage and evolutionary histories of compositionally distinct magmas, we investigate physical and chemical characteristics of andesitic and dacitic magmas feeding the 1986 eruption. We calculate equilibrium temperatures and oxygen fugacities from Fe-Ti oxide compositions and find a continuous range in temperature from 877 to 947°C and high oxygen fugacities (ΔNNO=1–2) for all magmas. Melt inclusions in pyroxene phenocrysts analyzed by Fourier-transform infrared spectroscopy and electron probe microanalysis are dacitic to rhyolitic and have water contents ranging from <1 to ∼7 wt%. Matrix glass compositions are rhyolitic and remarkably similar (∼75.9–76.6 wt% SiO2) in all samples. All samples have ∼25% phenocrysts, but lower-silica samples have much higher microlite contents than higher-silica samples. Continuous ranges in temperature and whole-rock composition, as well as linear trends in Harker diagrams and disequilibrium mineral textures, indicate that the 1986 magmas are the product of mixing between dacitic magma and a hotter, more mafic magma. The dacitic endmember is probably residual magma from the previous (1976) eruption of Augustine, and we interpret the mafic endmember to have been intruded from depth. Mixing appears to have continued as magmas ascended towards the vent. We suggest that the physical structure of the magma storage system beneath Augustine contributed to the sustained compositional heterogeneity of this eruption, which is best explained by magma storage and interaction in a vertically extensive system of interconnected dikes rather than a single coherent magma chamber and/or conduit. The typically short repose period (∼10 years) between Augustine's recent eruptive pulses may also inhibit homogenization, as short repose periods and chemically heterogeneous magmas are observed at several volcanoes in the Cook Inlet region of Alaska.
Turbulenzübergang in der Rohrströmung: Die Lösung eines alten Rätsels
NASA Astrophysics Data System (ADS)
Eckhardt, Bruno; Hof, Björn; Faisst, Holger
2006-09-01
Die Strömung von Flüssigkeiten und Gasen durch eine Röhre kann zwei Zustände annehmen. Einer ist laminar, also gleichmäßig geordnet, einer ist zeitlich-räumlich verwirbelt und turbulent. Mit dem Übergang zur Turbulenz nimmt der Strömungswiderstand drastisch zu. Vor etwa 120 Jahren beschrieb Osborne Reynolds bereits das Verhalten der Rohrströmung sehr genau. Er beobachtete, dass der Turbulenzübergang sehr empfindlich von äußeren Störungen abhängt, was bislang rätselhaft blieb. Dieses Rätsel konnte nun mit einer Kombination aus Computerstudien, Konzepten aus der nichtlinearen Dynamik und speziell entwickelten Experimenten gelöst werden.
Getahun, A.; Reed, M.H.; Symonds, R.
1996-01-01
Intensely altered wall rock was collected from high-temperature (640??C) and low-temperature (375??C) vents at Augustine volcano in July 1989. The high-temperature altered rock exhibits distinct mineral zoning differentiated by color bands. In order of decreasing temperature, the color bands and their mineral assemblages are: (a) white to grey (tridymite-anhydrite); (b) pink to red (tridymite-hematite-Fe hydroxide-molysite (FeCl3) with minor amounts of anhydrite and halite); and (c) dark green to green (anhydrite-halite-sylvite-tridymite with minor amounts of molysite, soda and potash alum, and other sodium and potassium sulfates). The alteration products around the low-temperature vents are dominantly cristobalite and amorphous silica with minor potash and soda alum, aphthitalite, alunogen and anhydrite. Compared to fresh 1986 Augustine lava, the altered rocks exhibit enrichments in silica, base metals, halogens and sulfur and show very strong depletions in Al in all alteration zones and in iron, alkali and alkaline earth elements in some of the alteration zones. To help understand the origins of the mineral assemblages in altered Augustine rocks, we applied the thermochemical modeling program, GASWORKS, in calculations of: (a) reaction of the 1987 and 1989 gases with wall rock at 640 and 375??C; (b) cooling of the 1987 gas from 870 to 100??C with and without mineral fractionation; (c) cooling of the 1989 gas from 757 to 100??C with and without mineral fractionation; and (d) mixing of the 1987 and 1989 gases with air. The 640??C gas-rock reaction produces an assemblage consisting of silicates (tridymite, albite, diopside, sanidine and andalusite), oxides (magnetite and hercynite) and sulfides (bornite, chalcocite, molybdenite and sphalerite). The 375??C gas-rock reaction produces dominantly silicates (quartz, albite, andalusite, microcline, cordierite, anorthite and tremolite) and subordinate amounts of sulfides (pyrite, chalcocite and wurtzite), oxides (magnetite), sulfates (anhydrite) and halides (halite). The cooling calculations produce: (a) anhydrite, halite, sylvite; (b) Cu, Mo, Fe and Zn sulfides; (c) Mg fluoride at high temperature (> 370??C); (d) chlorides, fluorides and sulfates of Mn, Fe, Zn, Cu and Al at intermediate temperature (170-370??C); and (e) hydrated sulfates, liquid sulfur, crystalline sulfur, hydrated sulfuric acid and water at low temperature ( 0.41 (> 628??C). This is followed by precipitation of sulfates of Fe, Cu, Pb, Zn and Al at lg/a ratios between 0.41 and -0.4 (628-178??C). At a lg/r ratio of < - 0.4 (178??C), anhydrous sulfates are replaced by their hydrated forms and hygroscopic sulfuric acid forms. At these low g/a ratios, hydrated sulfuric acid becomes the dominant phase in the system. Comparison of the thermochemical modeling results with the natural samples suggests that the alteration assemblages include: (1) minerals that precipitate from direct cooling of the volcanic gas; (2) phases that form by volcanic gases mixing with air; and (3) phases that form by volcanic gas-air-rock reaction. A complex interplay of the three processes produces the observed mineral zoning. Another implication of the numerical simulation results is that most of the observed incrustation and sublimate minerals apparently formed below 700??C.
Component-Level Demonstration of a Microfabricated Atomic Frequency Reference
2005-08-01
Kitching, L. A. Liew, and J. Moreland, "A microfabricated atomic clock," Applied Physics Letters, vol. 85, pp. 1460-1462, 2004. [4] R. Lutwak , P...Symposium on Frequency Standards and Metrology, P. Gill, Ed. St. Andrews, Scotland: World Scientific, 2001, pp. 155-166. [31] R. Lutwak , D. Emmons...Frequency and Time Forum. Tampa, FL, 2003, pp. 31-32. [71] R. Lutwak , D. Emmons, T. English, W. Riley, A. Duwel, M. Varghese, D. K. Serkland, and
NEEMO 21: Tools, Techniques, Technologies & Training for Science Exploration EVA
NASA Technical Reports Server (NTRS)
Graff, Trevor
2016-01-01
The 21st mission of the NASA Extreme Environment Mission Operations (NEEMO) was a highly integrated operational test and evaluation of tools, techniques, technologies, and training for science driven exploration during Extravehicular Activity (EVA).The 16-day mission was conducted from the Aquarius habitat, an underwater laboratory, off the coast of Key Largo, FL. The unique facility, authentic science objectives, and diverse skill-sets of the crew/team facilitate the planning and design for future space exploration.
Symonds, R.B.; Rose, William I.; Gerlach, T.M.; Briggs, P.H.; Harmon, R.S.
1990-01-01
After the March-April 1986 explosive eruption a comprehensive gas study at Augustine was undertaken in the summers of 1986 and 1987. Airborne COSPEC measurements indicate that passive SO2 emission rates declined exponentially during this period from 380??45 metric tons/day (T/D) on 7/24/86 to 27??6 T/D on 8/24/87. These data are consistent with the hypothesis that the Augustine magma reservoir has become more degassed as volcanic activity decreased after the spring 1986 eruption. Gas samples collected in 1987 from an 870??C fumarole on the andesitic lava dome show various degrees of disequilibrium due to oxidation of reduced gas species and condensation (and loss) of H2O in the intake tube of the sampling apparatus. Thermochemical restoration of the data permits removal of these effects to infer an equilibrium composition of the gases. Although not conclusive, this restoration is consistent with the idea that the gases were in equilibrium at 870??C with an oxygen fugacity near the Ni-NiO buffer. These restored gas compositions show that, relative to other convergent plate volcanoes, the Augustine gases are very HCl rich (5.3-6.0 mol% HCl), S rich (7.1 mol% total S), and H2O poor (83.9-84.8 mol% H2O). Values of ??D and ??18O suggest that the H2O in the dome gases is a mixture of primary magmatic water (PMW) and local seawater. Part of the Cl in the Augustine volcanic gases probably comes from this shallow seawater source. Additional Cl may come from subducted oceanic crust because data by Johnston (1978) show that Cl-rich glass inclusions in olivine crystals contain hornblende, which is evidence for a deep source (>25km) for part of the Cl. Gas samples collected in 1986 from 390??-642??C fumaroles on a ramp surrounding the inner summit crater have been oxidized so severely that restoration to an equilibrium composition is not possible. H and O isotope data suggest that these gases are variable mixtures of seawater, FMW, and meteoric steam. These samples are much more H2O-rich (92%-97% H2O) than the dome gases, possibly due to a larger meteoric steam component. The 1986 samples also have higher Cl/S, S/C, and F/Cl ratios, which imply that the magmatic component in these gases is from the more degassed 1976 magma. Thus, the 1987 samples from the lava dome are better indicators than the 1986 samples of degassing within the Augustine magma reservoir, even though they were collected a year later and contain a significant seawater component. Future gas studies at Augustine should emphasize fumaroles on active lava domes. Condensates collected from the same lava-dome fumarole have enrichments ot 107-102 in Cl, Br, F, B, Cd, As, S, Bi, Pb, Sb, Mo, Zn, Cu, K, Li, Na, Si, and Ni. Lower-temperature (200??-650??C) fumaroles around the volcano are generally less enriched in highly volatile elements. However, these lower-termperature fumaroles have higher concentration of rock-forming elements, probably derived from the wall rock. ?? 1990 Springer-Verlag.
NASA Astrophysics Data System (ADS)
Symonds, Robert B.; Rose, William I.; Gerlach, Terrence M.; Briggs, Paul H.; Harmon, Russell S.
1990-05-01
After the March April 1986 explosive eruption a comprehensive gas study at Augustine was undertaken in the summers of 1986 and 1987. Airborne COSPEC measurements indicate that passive SO2 emission rates declined exponentially during this period from 380±45 metric tons/day (T/D) on 7/24/86 to 27±6 T/D on 8/24/87. These data are consistent with the hypothesis that the Augustine magma reservoir has become more degassed as volcanic activity decreased after the spring 1986 eruption. Gas samples collected in 1987 from an 870°C fumarole on the andesitic lava dome show various degrees of disequilibrium due to oxidation of reduced gas species and condensation (and loss) of H2O in the intake tube of the sampling apparatus. Thermochemical restoration of the data permits removal of these effects to infer an equilibrium composition of the gases. Although not conclusive, this restoration is consistent with the idea that the gases were in equilibrium at 870°C with an oxygen fugacity near the Ni-NiO buffer. These restored gas compositions show that, relative to other convergent plate volcanoes, the Augustine gases are very HCl rich (5.3 6.0 mol% HCl), S rich (7.1 mol% total S), and H2O poor (83.9 84.8 mol% H2O). Values of δD and δ18O suggest that the H2O in the dome gases is a mixture of primary magmatic water (PMW) and local seawater. Part of the Cl in the Augustine volcanic gases probably comes from this shallow seawater source. Additional Cl may come from subducted oceanic crust because data by Johnston (1978) show that Cl-rich glass inclusions in olivine crystals contain hornblende, which is evidence for a deep source (>25km) for part of the Cl. Gas samples collected in 1986 from 390° 642°C fumaroles on a ramp surrounding the inner summit crater have been oxidized so severely that restoration to an equilibrium composition is not possible. H and O isotope data suggest that these gases are variable mixtures of seawater, FMW, and meteoric steam. These samples are much more H2O-rich (92% 97% H2O) than the dome gases, possibly due to a larger meteoric steam component. The 1986 samples also have higher Cl/S, S/C, and F/Cl ratios, which imply that the magmatic component in these gases is from the more degassed 1976 magma. Thus, the 1987 samples from the lava dome are better indicators than the 1986 samples of degassing within the Augustine magma reservoir, even though they were collected a year later and contain a significant seawater component. Future gas studies at Augustine should emphasize fumaroles on active lava domes. Condensates collected from the same lava-dome fumarole have enrichments ot 107 102 in Cl, Br, F, B, Cd, As, S, Bi, Pb, Sb, Mo, Zn, Cu, K, Li, Na, Si, and Ni. Lower-temperature (200° 650°C) fumaroles around the volcano are generally less enriched in highly volatile elements. However, these lower-termperature fumaroles have higher concentration of rock-forming elements, probably derived from the wall rock.
Ultrasonography assessment of vocal cords mobility in children after cardiac surgery.
Shaath, Ghassan A; Jijeh, Abdulraouf; Alkurdi, Ahmad; Ismail, Sameh; Elbarbary, Mahmoud; Kabbani, Mohamed S
2012-07-01
Upper airway obstruction after pediatric cardiac surgery is not uncommon. In the cardiac surgical population, an important etiology is vocal cord paresis or paralysis following extubation. In this study, we aimed to evaluate the feasibility and accuracy of ultrasonography (US) assessment of the vocal cords mobility and compare it to fiber-optic laryngoscope (FL). A prospective pilot study has been conducted in Pediatric Cardiac ICU (PCICU) at King Abdulaziz Cardiac Center (KACC) from the 1st of June 2009 till the end of July 2010. Patients who had cardiac surgery manifested with significant signs of upper airway obstruction were included. Each procedure was performed by different operators who were blinded to each other report. Results of invasive (FL) and non-invasive ultrasonography (US) investigations were compared. Ten patients developed persistent significant upper airway obstruction after cardiac surgery were included in the study. Their mean ± SEM of weight and age were 4.6 ± 0.4 kg and 126.4 ± 51.4 days, respectively. All patients were referred to bedside US screening for vocal cord mobility. The results of US were compared subsequently with FL findings. Results were identical in nine (90%) patients and partially different in one (10%). Six patients showed abnormal glottal movement while the other four patients demonstrated normal vocal cords mobility by FL. Sensitivity of US was 100% and specificity of 80%. US assessment of vocal cord is simple, non-invasive and reliable tool to assess vocal cords mobility in the critical care settings. This screening tool requires skills that can be easily obtained.
Coombs, Michelle L.; Vazquez, Jorge A.
2014-01-01
Augustine Volcano, a frequently active andesitic island stratocone, erupted a late Pleistocene rhyolite pumice fall that is temporally linked through zircon geochronology to cumulate dioritic blocks brought to the surface in Augustine's 2006 eruption. Zircon from the rhyolite yield a 238U-230Th age of ∼25 ka for their unpolished rims, and their interiors yield a bimodal age populations at ∼26 ka and a minority at ∼41 ka. Zircon from dioritic blocks, ripped from Augustine's shallow magmatic plumbing system and ejected during the 2006 eruption, have interiors defining a ∼26 ka age population that is indistinguishable from that for the rhyolite; unpolished rims on the dioritic zircon are dominantly younger (≤12 ka) indicating subsequent crystallization. Zircon from rhyolite and diorite overlap in U, Hf, Ti, and REE concentrations although diorites also contain a second population of high-U, high temperature grains. Andesites that brought dioritic blocks to the surface in 2006 contain zircon with young (≤9 ka) rims and a scattering of older ages, but few zircon that crystallized during the 26 ka interval. Both the Pleistocene-age rhyolite and the 2006 dioritic inclusions plot along a whole-rock compositional trend distinct from mid-Holocene–present andesites and dacites, and the diorites, rhyolite, and two early Holocene dacites define linear unmixing trends often oblique to the main andesite array and consistent with melt (rhyolite) extraction from a mush (dacites), leaving behind a cumulate amphibole-bearing residue (diorites). Rare zircon antecrysts up to ∼300 ka from all rock types indicate that a Quaternary center has been present longer than preserved surficial deposits.
Syracuse, E.M.; Thurber, C.H.; Power, J.A.
2011-01-01
We incorporate 14 years of earthquake data from the Alaska Volcano Observatory with data from a 1975 controlled-source seismic experiment to obtain the three-dimensional P and S wave velocity structure and the first high-precision earthquake locations at Augustine Volcano to be calculated in a fully three-dimensional velocity model. Velocity tomography shows two main features beneath Augustine: a narrow, high-velocity column beneath the summit, extending from ???2 km depth to the surface, and elevated velocities on the south flank. Our relocation results allow a thorough analysis of the spatio-temoral patterns of seismicity and the relationship to the magmatic and eruptive activity. Background seismicity is centered beneath the summit at an average depth of 0.6 km above sea level. In the weeks leading to the January 2006 eruption of Augustine, seismicity focused on a NW-SE line along the trend of an inflating dike. A series of drumbeat earthquakes occurred in the early weeks of the eruption, indicating further magma transport through the same dike system. During the six months following the onset of the eruption, the otherwise quiescent region 1 to 5 km below sea level centered beneath the summit became seismically active with two groups of earthquakes, differentiated by frequency content. The deep longer-period earthquakes occurred during the eruption and are interpreted as resulting from the movement of magma toward the summit, and the post-eruptive shorter-period earthquakes may be due to the relaxation of an emptied magma tube. The seismicity subsequently returned to its normal background rates and patterns. Copyright 2011 by the American Geophysical Union.
BRIK, An Interactive, Goal Programming Model for Nuclear Exchange Problems
1984-03-01
Hedging),(ZW d-),(de+)) 2) min (( Td ),(Hedging),(Tdj-),(Zdi7),(de+)) 3) min ((Zd +),(2:d +),(Hedging),(d )) Constraint Set st: -. (nS ij)yi j + dj...1 Z; L- L) U u~ c) r-c L 00 0 0 0) +* -’ 0ki I . 9-I 0 t- ’f) +fl -4-4C N- M1-~C q, b") u3 Ul)4) . a) 0f c~4 ) al N U- 4) i Ill aj - X 111 a 10 C L
1992-10-01
The concept of using a temperature sensor in a pill as a clinical thermometer Is good, but mobility of the pill makes it less suitable as a research...Human Technologies, Inc. (CorTempt m; St. Petersburg, FL). Both systems included an ingestible temperature sensor /pill, a receiver, and a data storage...telemetry pills did, and T, and T. showed a faster response to changing core temperature than did T,. The concept of using a temperature sensor in a
1980-02-01
USAFA-TR-A-NL mhmmmhhhhhhhIEhhhhhEEEEa IIIIII. iiiii ,_oi ,o 虡 11112. 41. 111IL25 MICROCOPY RESOLUTION TEST C *AT NATIONAL BUREAU Or ST/fl) ARDS-1963-0...UNCLASSIFIED SCCUftIlY CLASSIFICATION OF T-40 PA@ C (Vhm Data Rateri.) USAPA-TR-80-4 PROBLE1S ASSOCIATED WITH MEANINGFUL RESEARCH ON THE EFFECTS OF...correlations (or non-correlations) of susceptibility of certain fungal taxa to inhibition by increased oxygen levels, c ) questionable reliability of results of
Method for Grey Scale Mapping of Underground Obstacles Using Video Pulse Radar Return
1978-12-01
the botton of Figure 3 is apparent. However, Figure 4 exhibits the one observed weakness of the Lagrange (or any polynomial) method. Large...t. . .. MWISS.S*4SW. - . W. . . SSV*V~t~fl~d*W*.StS . W ..... *W... *sn AW ~oo .*IB.Se.ve SWWZ.WWT...W. . . WVW.S* . *SS~SUA*.. ........ 0.305 mi stilf...5533 .. ... tel +lllt~llllllllllllllllll~l~ll............. . : .......lI~lI I llll~~ll .---I e~ ---- ..... lot I s 1 1i ....... IEr .5C
Preliminary volcano-hazard assessment for Augustine Volcano, Alaska
Waythomas, Christopher F.; Waitt, Richard B.
1998-01-01
Augustine Volcano is a 1250-meter high stratovolcano in southwestern Cook Inlet about 280 kilometers southwest of Anchorage and within about 300 kilometers of more than half of the population of Alaska. Explosive eruptions have occurred six times since the early 1800s (1812, 1883, 1935, 1964-65, 1976, and 1986). The 1976 and 1986 eruptions began with an initial series of vent-clearing explosions and high vertical plumes of volcanic ash followed by pyroclastic flows, surges, and lahars on the volcano flanks. Unlike some prehistoric eruptions, a summit edifice collapse and debris avalanche did not occur in 1812, 1935, 1964-65, 1976, or 1986. However, early in the 1883 eruption, a portion of the volcano summit broke loose forming a debris avalanche that flowed to the sea. The avalanche initiated a small tsunami reported on the Kenai Peninsula at English Bay, 90 kilometers east of the volcano. Plumes of volcanic ash are a major hazard to jet aircraft using Anchorage International and other local airports. Ashfall from future eruptions could disrupt oil and gas operations and shipping activities in Cook Inlet. Eruptions similar to the historical and prehistoric eruptions are likely in Augustine's future.
Volatile Contents in Mafic Magmas from two Aleutian volcanoes: Augustine and Makushin
NASA Astrophysics Data System (ADS)
Zimmer, M. M.; Plank, T.; Hauri, E. H.; Nye, C.; Faust Larsen, J.; Kelemen, P. B.
2004-12-01
There are several competing theories for the origin of tholeiitic (TH) vs. calc-alkaline (CA) fractionation trends in arc magmas. One relates to water (TH-dry magma, CA-wet magma), another to pressure (TH-low pressure crystallization, CA-high pressure), and a third to primary magma composition (TH-low Si/Fe#, CA-hi Si/Fe#) These theories have been difficult to test without quantitative measures of the water contents and pressures of crystallization of arc magmas. We are in the process of studying several Aleutian arc tephra suites (phenocrysts and melt inclusions) with the aim of obtaining volatile element concentrations (by SIMS), major and trace element concentrations and thermobarometric data (by EMP and laser-ICPMS). We report preliminary results on olivine-hosted melt inclusions from Augustine and Makushin volcanoes that support the role of water in calc-alkaline fractionation. Basaltic melt inclusions from Augustine, a low-K2O, calc-alkaline volcano, are hosted in Fo80-82 olivine. The inclusions yield high water contents, up to 5 wt%, and contain 60-90 ppm CO2, 3000-4500 ppm S, and 3000-6000 ppm Cl. Inclusions record vapor-saturation pressures near 2 kbar. Cl/K2O ratios in Augustine inclusions (ave. 1.9) are among the highest documented in an arc setting, and likely record a Cl- and H2O- rich fluid from the subducting plate. High water contents in Augustine primary melts may have contributed to the strong calc-alkaline trend observed at this volcano. Basaltic melt inclusions from Pakushin, a medium-K2O, tholeiitic cone on the flanks of Makushin volcano, are hosted in Fo80-86 olivine. These inclusions have low water contents (<0.15 wt%) and low CO2 contents (<125 ppm), and record shallow vapor saturation pressures (<300 bars). The high sulfur (2000-4000 ppm) and Cl (>2000 ppm) in Pakushin melt inclusions, however, indicate that degassing was minimal. The low water contents and low vapor saturation pressures recorded in Pakushin melt inclusions are consistent with development of its tholeiitic trend, but we cannot distinguish whether the low water contents at Pakushin reflect a difference in the primary magma, or in crustal stresses that favor low pressure fractionation and degassing. These questions will be addressed with further work on the trace element contents of the melt inclusions and on phenocryst-melt geobarometers.
NASA Technical Reports Server (NTRS)
Colloredo, Scott; Gray, James A.
2011-01-01
The impending conclusion of the Space Shuttle Program and the Constellation Program cancellation unveiled in the FY2011 President's budget created a large void for human spaceflight capability and specifically launch activity from the Florida launch Site (FlS). This void created an opportunity to re-architect the launch site to be more accommodating to the future NASA heavy lift and commercial space industry. The goal is to evolve the heritage capabilities into a more affordable and flexible launch complex. This case study will discuss the FlS architecture evolution from the trade studies to select primary launch site locations for future customers, to improving infrastructure; promoting environmental remediation/compliance; improving offline processing, manufacturing, & recovery; developing range interface and control services with the US Air Force, and developing modernization efforts for the launch Pad, Vehicle Assembly Building, Mobile launcher, and supporting infrastructure. The architecture studies will steer how to best invest limited modernization funding from initiatives like the 21 st elSe and other potential funding.
NASA Astrophysics Data System (ADS)
Zand-Moghadam, Hamed; Moussavi-Harami, Reza; Mahboubi, Asadollah; Aghaei, Ali
2016-05-01
The Upper Jurassic (Oxfordian-Kimmeridgian) Mozduran Formation is the most important gas reservoirs of the northeast Iran. Siliciclastic facies of this formation in eastern most parts of the basin have not been studied yet. Therefore, four stratigraphic sections of Mozduran Formation have been selected in the Kole-Malekabad, Kale-Karab, Deraz-Ab and Karizak to interpret depositional history and analyze depositional sequences. Based on texture and sedimentary structures, 14 slilciclastic lithofacies were identified and classified into four categories, including conglomerate (Gms, Gp, Gt), sandstone (Sh, Sp, St, Sr, Sl, Sm, Se), mud rock (Fl) and intermediate sandstone-mud rock (Sr (Fl), Sr/Fl, Fl (Sr)). Identified lithofacies formed four architectural elements CH, SB, LA and FF. Lithofacies characteristics and architectural elements with mostly bimodal pattern of paleocurrents show that the majority of Mozduran lithofacies deposited in the coastal environment (tidal influence). Sequence stratigraphic analysis shows that the Kole-Malekabad section consists of two depositional sequences while other sections are characterized by three depositional sequences. The lower and upper sequence boundaries of the Mozduran Formation in all stratigraphic sections are SB1 that are distinguished by paleosol and sometime conglomerate horizons. Most of depositional sequences in studied sections are composed only of TST and HST. The TST deposits consist mostly of quartzarenite and litharenite petrofacies that have been deposited in the tidal zone. HST packages are mostly including mud rocks with interdeds of sandstone lithofacies that are deposited in supratidal setting. The LST facies is recognized only in the DS3 (equivalent to the second depositional sequences of the Kole-Malekabad), which consist of conglomerate facies. Instead, the Kole-Malekabad section is often composed of supratidal gypsiferrous shales, indicating sea level fall in the study area.
Venezky, Dina Y.; Murray, Tom; Read, Cyrus
2008-01-01
Steam plume from the 2006 eruption of Augustine volcano in Cook Inlet, Alaska. Explosive ash-producing eruptions from Alaska's 40+ historically active volcanoes pose hazards to aviation, including commercial aircraft flying the busy North Pacific routes between North America and Asia. The Alaska Volcano Observatory (AVO) monitors these volcanoes to provide forecasts of eruptive activity. AVO is a joint program of the U.S. Geological Survey (USGS), the Geophysical Institute of the University of Alaska Fairbanks (UAFGI), and the State of Alaska Division of Geological and Geophysical Surveys (ADGGS). AVO is one of five USGS Volcano Hazards Program observatories that monitor U.S. volcanoes for science and public safety. Learn more about Augustine volcano and AVO at http://www.avo.alaska.edu.
Second trimester fetal nasal bone length in a low-risk Turkish population.
Yanik, Filiz Fatma; Eroglu, Derya; Baser, Eralp; Dursun, Polat; Karakaya, Burcu Kisa
2011-10-01
To define normal values of second trimester fetal nasal bone length (NBL) in a low-risk Turkish population. Prenatal records of singleton fetuses who underwent second trimester ultrasonographic examination in the 16 to 23 weeks of pregnancy were retrospectively analyzed for NBL and biometric measurements (BPD, FL and HL). The relationship among NBL and gestational age (GA), biparietal diameter (BPD), femur length (FL) and humerus length (HL) was determined. Additionally, percentile values of NBL for each gestational week were provided. A total of 1467 fetuses were included in this study. There was a significant linear association among NBL and GA (R(2) = 0.709), BPD (R(2) = 0.752), FL (R(2) = 0.742) and HL (R(2) = 0.747). Fifth percentile values of fetal NBL were 3.11 mm for 16th, 3.50 mm for 17th, 3.70 mm for 18th, 4.10 mm for 19th, 4.50 mm for 20th, 4.62 mm for 21st, 5.24 mm for 22nd and 5.37 mm for 23rd gestational weeks. The study provides normal ranges of NBL between 16 and 23 weeks of pregnancy in a low-risk Turkish population. Future studies with larger sample sizes including pregnancies carrying high risk for aneuploidy are needed to define cut-off values for NBL. Copyright © 2011 John Wiley & Sons, Ltd.
Crane, Michael; Clayton, Tonya; Raabe, Ellen; Stoker, Jason M.; Handley, Larry; Bawden, Gerald W.; Morgan, Karen; Queija, Vivian R.
2004-01-01
The first United States Geological Survey (USGS) Light Detection And Ranging (lidar) Workshop was held November 20-22, 2002 in St. Petersburg, Florida to bring together scientists and managers from across the agency. The workshop agenda focused on six themes: 1) current and future lidar technologies, 2) lidar applications within USGS science and disciplines, 3) calibration and accuracy assessment, 4) tools for processing and evaluating lidar data sets, 5) lidar data management, and 6) commercial and contracting issues. These six themes served as the topics for workshop plenary sessions as well as the general focus for associated breakout sessions. A number of recommendations are presented regarding the role the USGS should play in the future application and development of lidar technology.
1988-05-31
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76 FR 43370 - Notice of Passenger Facility Charge (PFC) Approvals and Disapprovals
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-20
... 06-05-C-01-CLL, College Station, TX...... 06/01/11 $799,557 $755,492 04/01/09 04/01/09 06-05-C-03-MOB, Mobile, AL 06/02/11 4,835,101 4,850,267 02/01/12 06/01/15 07-02-C-01-ECP, Panama City, FL 06/02/11 41,968,640 41,968,640 04/01/39 04/01/39 92-01-C-06-STL, St. Louis, MO 06/02/11 58,088,964 84,607,850 08/01/95...
TET Offensive II Field Force Vietnam After Action Report 31 January - 18 February 1968
1968-03-01
and the 5th VC Division. V During this same period of time there were no majur shifts in ARVN forces . However III Corps shifted three...8217-".•: ’ ’SSIFJED U.S. ARMY. VIETNAM. II FIELD FORCE . TET OFFENSIVE II FIELD FORCE VIETNAM AFTER ACTION REPORT, 31 JANUARY-18 FEB- RUARY 1968...H FIELD FORCE VIETNAM AFTER ACTION REPORT 31 January-18 February 1968 RECORD K0- ! FlSjl fi-.-A-,>-•: it tT*\\ : *si h s» -wP Mr-, £< St
1946-08-21
artillery, but the main troubles came in operating heavy vehicles through muddy fields, slippery trails, and hedgerows. The II9th Infantry felt...Army’s attack began, continued to balk aerial reconnaissance and to make the roads slippery and muddy. The axis of advance of the attacking task...JuLTI J ! VII - XIX CoIIps IOUNOIJIY AS OF 6 JULY .....lIT, If’ III IIIET!!!!. I o " ’" •’" .. flU ( \\ J Elm ’ "’/1’ v,",f «. ? --/ F:rm~91
500-Watt Solid-State RF Power Amplifier AM-7209( )/VRC.
1983-03-18
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Fort Greely Missile Range Reference Atmosphere. Part 2
1971-07-10
QUANTITIES FOR OrkEELY MISSILE FAIRBANKS, AL4VSKAI 134 649 N 147052’ We JAN1961 -DEC1I96 NE6AUC ST Lo STE-FT GELY . ??2 -103- 5W N 145043’ W 63750 e3298.5...2048175 316.025I - ~~~24v.i~h 7c3r3V’-.3t75- t6.,79- k-35000 34069.4 24W.95 6.8016240 v.arv9557 316.931 E -ss 351 .2 25U.00 6,5753944 fl.1 -31I.394
1984-11-29
Support, and Property Construction, Mediterranean, Madrid, Commander Third Fleet, Pear Harbor. HI Spain T40083 Multilocation Audit of Table of Equip- 5...and Interest 2 Office, Bay St Louis, MS AcontBlacsaso 3 etebr 93X40044L Unannounced Audit of Disbursing 5/3/84 T20103 Multilocation Audit of the...udte Fot isbring, At h rn n er 8 Support Aivits . Naval Air Statio, T20063 Multilocation Audit of the Marine Corps 6/5/84 Jacksonville. FlI. joint
NASA Astrophysics Data System (ADS)
Webster, J. D.; Mandeville, C. W.; Gerard, T.; Goldoff, B.; Coombs, M. L.
2006-12-01
Augustine Volcano, Cook Inlet, Alaska, is a subduction-related Aleutian arc volcano located approximately 275 km southwest of Anchorage. During the past 200 years, Augustine volcano has shown explosive eruptive behavior seven times, with the most recent activity occurring in January through March 2006. Its ash and pumice eruptions pose a threat to commercial air traffic, the local fishing industry, and the inhabitants of the region. Following prior investigations on volatile abundances and processes of evolution for magmas associated with the 1976 (Johnston, 1978) and 1986 (Roman et al., 2005) eruptions of Augustine, we have analyzed phenocrysts, matrix glasses, and silicate melt inclusions in andesites formed during 5 pre-historic eruptions (ranging from 2100 to 1000 years in age) as well as the 1986 and recent 2006 eruptions. Outcrops of basaltic units on Augustine are rare, and basaltic melt inclusions are as well, so most melt inclusions studied range from andesitic to rhyolitic compositions. Comparison of the volatile abundances in felsic melt inclusion glasses shows few differences in H2O, CO2, S, and Cl, respectively, between eruptive materials of the pre- historic, 1976 (Johnston, 1978), and 1986 (Roman et al., 2005; our data) events. The magmas associated with these eruptions contained 1.6 to 8.0 wt.% H2O with 0.21 to 0.84 wt.% Cl, 100 to 1800 ppm CO2, and 100 to 400 ppm S. In contrast, preliminary research on rhyodacitic to rhyolitic melt inclusions in a single 2006 andesite sample collected from a lahar deposit indicates they contain somewhat lower H2O contents and higher Cl and S abundances than felsic melt inclusions from prior eruptions, and they exhibit geochemical trends consonant with magma mixing. Relationships involving H2O, CO2, S, and Cl in prehistoric through 1986 melt inclusions are consistent with fluid-saturated magma evolution of andesitic to rhyolitic melt compositions during closed-system ascent. The various batches of magma rose through dikes to depths as shallow as 2.4 to 0.6 km, at which stage the fluid or fluids began to separate from magma. Fluid separation may have generated some of the seismic signals recorded at these depths during pre-2006 volcanic eruptions. We will examine 2006 juvenile material to evaluate whether or not similar processes of magma evolution and ascent were operative. Johnston D.A. (1978) Univ. Washington unpub. Ph.D. dissertation. Roman, D.C., et al. (2005) Bull. Volcanol. 84:240-254.
Combined Use of Terrestrial Laser Scanning and IR Thermography Applied to a Historical Building
Costanzo, Antonio; Minasi, Mario; Casula, Giuseppe; Musacchio, Massimo; Buongiorno, Maria Fabrizia
2015-01-01
The conservation of architectural heritage usually requires a multidisciplinary approach involving a variety of specialist expertise and techniques. Nevertheless, destructive techniques should be avoided, wherever possible, in order to preserve the integrity of the historical buildings, therefore the development of non-destructive and non-contact techniques is extremely important. In this framework, a methodology for combining the terrestrial laser scanning and the infrared thermal images is proposed, in order to obtain a reconnaissance of the conservation state of a historical building. The proposed case study is represented by St. Augustine Monumental Compound, located in the historical centre of the town of Cosenza (Calabria, South Italy). Adopting the proposed methodology, the paper illustrates the main results obtained for the building test overlaying and comparing the collected data with both techniques, in order to outline the capabilities both to detect the anomalies and to improve the knowledge on health state of the masonry building. The 3D model, also, allows to provide a reference model, laying the groundwork for implementation of a monitoring multisensor system based on the use of non-destructive techniques. PMID:25609042
Combined use of terrestrial laser scanning and IR thermography applied to a historical building.
Costanzo, Antonio; Minasi, Mario; Casula, Giuseppe; Musacchio, Massimo; Buongiorno, Maria Fabrizia
2014-12-24
The conservation of architectural heritage usually requires a multidisciplinary approach involving a variety of specialist expertise and techniques. Nevertheless, destructive techniques should be avoided, wherever possible, in order to preserve the integrity of the historical buildings, therefore the development of non-destructive and non-contact techniques is extremely important. In this framework, a methodology for combining the terrestrial laser scanning and the infrared thermal images is proposed, in order to obtain a reconnaissance of the conservation state of a historical building. The proposed case study is represented by St. Augustine Monumental Compound, located in the historical centre of the town of Cosenza (Calabria, South Italy). Adopting the proposed methodology, the paper illustrates the main results obtained for the building test overlaying and comparing the collected data with both techniques, in order to outline the capabilities both to detect the anomalies and to improve the knowledge on health state of the masonry building. The 3D model, also, allows to provide a reference model, laying the groundwork for implementation of a monitoring multisensor system based on the use of non-destructive techniques.
Naranjo, Diana P; Qualls, Whitney A; Müller, Gunter C; Samson, Dayana M; Roque, Deborah; Alimi, Temitope; Arheart, Kristopher; Beier, John C; Xue, Rui-De
2013-04-01
Attractive toxic sugar bait (active ingredient, 1% boric acid) was evaluated against Aedes albopictus Skuse populations in the laboratory, semi-field trials, and field trials in residential communities in St. Augustine, Florida. Laboratory evaluations of boric acid sugar baits applied to the plant Pentas lanceolata (Rubiaceae) demonstrated 100 and 92% mortality of A. albopictus at day 7 and 14, respectively. A semi-field study evaluating the bait application to the upperside or topside of leaves resulted in no significant difference on mortality (P>0.05). Overall combined top and bottom boric acid sugar bait application mortality at day 7 was 95% based on leaf bioassays. Field application of the boric acid sugar baits significantly (P<0.05) decreased adult A. albopictus populations up to day 21 post-treatment compared to the pre-treatment population numbers. A significant reduction in oviposition was demonstrated both at day 7 and 14 post-application (P=0.001) as monitored by ovitraps. Attractive toxic sugar bait application in tropical environments demonstrated efficacy, persistence, and feasibility in controlling A. albopictus populations.
Restructuring opens new doors. Business ventures redirect deflected revenue.
Moore, R F
1989-01-01
To fulfill its mission of caring for the sick and the poor while remaining competitive, St. Vincent's Medical Center, Jacksonville, FL, underwent corporate restructuring in 1983. Three existing entities--the medical center, a skilled nursing facility, and a fund-raising foundation--incorporated under St. Vincent dePaul Community Stewardship Services, Inc. One of the goals was to make optimal use of existing facilities and expertise while also creating channels to redirect deflected revenue to the corporate mission of service to the poor. Among its projects St. Vincent's established 12 ambulatory care facilities; offered use of its laboratory to physicians' offices, nursing homes, and other entities needing fast, high-quality service; developed a mobile magnetic resonance imaging service; created a nurse staffing business; and entered into services-oriented, price-competitive, for-profit operations. By assuming some of the broad-based responsibilities for planning, financing, marketing, and providing administrative and legal support, the parent company has freed the entities under it to concentrate on the jobs they do best: the delivery of healthcare products and services and the generation of referrals to the medical staff and, in turn, to the medical center.
Notes on "bioethics and sin" by Jean-Francois Collange.
Cozby, Dimitri
2005-08-01
Placing the notion of sin in the context of a meontic account of evil, and emphasizing the effect of sin on the sinner himself, this commentary exposes the insufficiency of restricting oneself to human efforts at atonement, and of thus underemphasizing the role of Christ. Collange's claim that the teaching of "predestination" is rooted in Paul and that the doctrine of merits and indulgences is rooted in Augustine is criticized, and Luther's "forensic" understanding is linked with Augustine, rather than with Paul. Collange's reduction of the concern for holiness to respect and trust is contrasted with holiness's essential context of loving unification with God. The commentary closes by exposing the unsatisfactory scantiness of Collange's treatment of cloning, health-care economy, and of the evils of life.
CO2calc: A User-Friendly Seawater Carbon Calculator for Windows, Mac OS X, and iOS (iPhone)
Robbins, L.L.; Hansen, M.E.; Kleypas, J.A.; Meylan, S.C.
2010-01-01
A user-friendly, stand-alone application for the calculation of carbonate system parameters was developed by the U.S. Geological Survey Florida Shelf Ecosystems Response to Climate Change Project in response to its Ocean Acidification Task. The application, by Mark Hansen and Lisa Robbins, USGS St. Petersburg, FL, Joanie Kleypas, NCAR, Boulder, CO, and Stephan Meylan, Jacobs Technology, St. Petersburg, FL, is intended as a follow-on to CO2SYS, originally developed by Lewis and Wallace (1998) and later modified for Microsoft Excel? by Denis Pierrot (Pierrot and others, 2006). Besides eliminating the need for using Microsoft Excel on the host system, CO2calc offers several improvements on CO2SYS, including: An improved graphical user interface for data entry and results Additional calculations of air-sea CO2 fluxes (for surface water calculations) The ability to tag data with sample name, comments, date, time, and latitude/longitude The ability to use the system time and date and latitude/ longitude (automatic retrieval of latitude and longitude available on iPhone? 3, 3GS, 4, and Windows? hosts with an attached National Marine Electronics Association (NMEA)-enabled GPS) The ability to process multiple files in a batch processing mode An option to save sample information, data input, and calculated results as a comma-separated value (CSV) file for use with Microsoft Excel, ArcGIS,? or other applications An option to export points with geographic coordinates as a KMZ file for viewing and editing in Google EarthTM
The Role of Epithelial Stat3 in Amelogenesis during Mouse Incisor Renewal.
Zhang, Bin; Meng, Bo; Viloria, Edward; Naveau, Adrien; Ganss, Bernhard; Jheon, Andrew H
2018-03-16
The aim of this study was to evaluate the role of epithelial signal transducer and activator of transcription 3 (STAT3) in mouse incisor amelogenesis. Since Stat3 is expressed in the epithelial component of developing and adult mouse teeth, we generated and analyzed Krt14Cre/+;Stat3fl/fl mutant mice in which Stat3 was inactivated in epithelia including ameloblast progenitors and ameloblasts, the cells responsible for enamel formation. Histological analysis showed little enamel matrix in mutant incisors compared to controls. Delayed incisor enamel mineralization was demonstrated using micro-computed X-ray tomography analysis and was supported by an increase in the pre-expression distance of enamel-enriched proteins such as amelogenin, ameloblastin, and kallikrein-4. Lastly, scanning electron microscopy analysis showed little enamel mineralization in mutant incisors underneath the mesial root of the 1st molar; however, the micro-architecture of enamel mineralization was similar in the erupted portion of control and mutant incisors. Taken together, our findings demonstrate for the first time that the absence of epithelial Stat3 in mice leads to delayed incisor amelogenesis. © 2018 S. Karger AG, Basel.
Human Space Flight Plans Committee
2009-08-11
Norman Augustine, chair, listens to a speaker's presentation during the final meeting of the Human Space Flight Review Committee, Wednesday, Aug. 12, 2009, in Washington. Photo Credit: (NASA/Paul E. Alers)
Exploration Architecture Options - ECLSS, EVA, TCS Implications
NASA Technical Reports Server (NTRS)
Chambliss, Joe; Henninger, Don; Lawrence, Carl
2009-01-01
Many options for exploration of the Moon and Mars have been identified and evaluated since the Vision for Space Exploration VSE was announced in 2004. Lunar architectures have been identified and addressed in the Lunar Surface Systems team to establish options for how to get to and then inhabit and explore the moon. The Augustine Commission evaluated human space flight for the Obama administration and identified many options for how to conduct human spaceflight in the future. This paper will evaluate the options for exploration of the moon and Mars and those of the Augustine human spaceflight commission for the implications of each architecture on the Environmental Control and Life Support, ExtraVehicular Activity and Thermal Control systems. The advantages and disadvantages of each architecture and options are presented.
Senate subcommittee examines NASA's identity crisis
NASA Astrophysics Data System (ADS)
Leath, Audrey T.
With the Cold War fading into history, economic competitiveness becoming the watchwords of the decade, and the space race against the Russians turning into probable cooperation, NASA is struggling to redefine its role. On November 16, the Senate Commerce Subcommittee on Science, Technology and Space invited NASA Administrator Daniel Goldin, Martin Marietta CEO Norman Augustine, and Robert Frosch of Harvard University's John F. Kennedy School of Government to offer their thoughts on NASA's plans, priorities, and budgetary difficulties. Augustine, who chaired the Committee on the Future of the U.S. Space Program in 1990, posed two questions: What does America want its space program to be, and can the country afford to pay for the program it wants? He stated bluntly that if the answers were incompatible, “we are unlikely to have a satisfactory program.”
Long-term contraction of pyroclastic flow deposits at Augustine Volcano using InSAR
NASA Astrophysics Data System (ADS)
McAlpin, D. B.; Meyer, F. J.; Lu, Z.; Beget, J. E.
2013-12-01
Augustine Island is a small, 8x11 km island in South Central Alaska's lower Cook Inlet. It is approximately 280 km southwest of Anchorage, and occupied entirely by its namesake Augustine Volcano. The volcano's nearly symmetrical central cone reaches an altitude of 1260 m, and the surrounding island is composed almost entirely of volcanic deposits. It is the youngest and most frequently active volcano in the lower Cook Inlet, with at least seven known eruptions since the beginning of written records in 1812. Its two most recent eruptions occurred during March-August 1986, and January-March 2006 The 1986 and 2006 Augustine eruptions produced significant pyroclastic flow deposits (PFDs) on the island, both which have been well mapped by previous studies. Subsidence of material deposited by these pyroclastic flows has been measured by InSAR data, and can be attributed to at least four processes: (1) initial, granular settling; (2) thermal contraction; (3) loading of 1986 PFDs from overlying 2006 deposits; and (4) continuing subsidence of 1986 PFDs buried beneath 2006 flows. For this paper, SAR data for PFDs from Augustine Volcano were obtained from 1992 through 2005, from 2006-2007, and from 2007-2011. These time frames provided InSAR data for long-term periods after both 1986 and 2006 eruptions. From time-series analysis of these datasets, deformation rates of 1986 PFDs and 2006 PFDs were determined, and corrections applied where newer deposits were emplaced over old deposits. The combination of data sets analyzed in this study enabled, for the first time, an analysis of long and short term subsidence rates of volcanic deposits emplaced by the two eruptive episodes. The generated deformation time series provides insight into the significance and duration of the initial settling period and allows us to study the thermal regime and heat loss of the PFDs. To extract quantitative information about thermal properties and composition of the PFDs, we measured the thickness of the PFDs using both multiple DEM comparison and InSAR time-series analysis. Together with the deformation measurements this thickness information will be used as input to a finite element model of a PFD and will allow us to investigate the PFD's thermo-elastic properties. The thickness information will be further used to understand whether the loading of 1986 PFDs from overlying 2006 deposits had a significant impact on the subsidence rate of buried 1986 deposits. Results from this investigation provide insight into post-emplacement behavior of PFDs and similar eruptive flows, and allow us to better understand the behavior of post emplacement volcanic deposits and their impacts on mapping magma-related deformation.
A Study of the Impact of the Lack of a Cost Accounting Standards Board.
1987-06-01
California 00 ,: SE P 9 7 THESIS SE& A STUDY OF THE IMPACT OF THE LACK OF A COST ACCOUNTING STANDARDS BOARD by James F. Sumner, III June 1987 Thesis...O’ATON COSA1. CODES 16 SuB,*CT j’J.45 Comr~nue n- p.ono ol neeeterV ani denltiy by flO(k f1LrmbCr) E,) ROUP StA IRucost accounting , cost accounting ...thesis has two purposes. First, it attempts to determine whether the absence of the Cost Accounting Standards Board (CASB) has given rise to any areas
Deformation of Extruded Titanium Alloys Under Superplastic Conditions
1988-07-01
176mm wide with a flange wall 37mm high x 27mm wide and a central web 122mm wide x 18mm thick. Round-bar test pieces aligned parallel to the principal...directions L, T and ST were extrac- ted from the flange and web as shown in Fig 1; gauge length dimensions were 15mm x 5.5mm diameter for the FST test...ares. in the gauge length. Flange Web X 9 NTIS GFA&I v FL Distribut I oc / A es ’- n:ia or Fig I Position of test pieces in extruded section iste i
Fundamental Studies on MPD Thrusters.
1987-09-02
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Word Frequency Analysis. MOS: 31N. Skill Levels 1 & 2.
1981-05-01
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Sadeghnia, Alireza; Ganji, Masoud; Armanian, Amir Mohammad
2014-09-01
Icter is the most prevalent disease in newborns. Although most of the newborns affiliated with this seem healthy in other aspects, there is always a fear for toxic complication of indirect hyperbilirobinemia in the central nervous system. Nowadays phototherapy is the method of decreasing (or avoidance of increase) of total serum bilirobin (TSB) and it is also used widely in neonatal health care centers according to the availably of equipment, but without any defined standard. In this study, two light sources, quarts halogen incandescent filament lamp (QHIFL) and fluorescent lamp (FL) are compared with each other to find out which method is more useful and efficient. This study is a randomized controlled trial done on 25 newborns with gestational age of 35 weeks or more, with newborn's icter in the 1(st) week after birth, at Isfahan Behesti Hospital, February 2012 to March 2013. A group of these newborns was treated with FL and the other with QHIFL and they all were controlled and tested according to their level of TSB at the beginning of phototherapy, at 8(th), 12(th), and 24(th) h of treatment and at discharge. The data from the study was analyzed by IBM SPSS Statistics Version 21. According to the findings, the level of TSB before and 8 h after the intervention had no significant difference among the groups. However, at 16(th) and 24(th) h of treatment, the TSB level was lower in the FL group and this difference was meaningful (P = 0.002 and P = 0.013 respectively). Furthermore the duration of the treatment was significantly shorter in FL group meaningfully (P = 0.047). According to the findings of this study, the technology used in QHIFL cannot show the capabilities of the FLs. However, more studies are needed to confirm the findings of this study are universal.
Collins, Richard L.; Fochesatto, Javier; Sassen, Kenneth; Webley, Peter W.; Atkinson, David E.; Dean, Kenneson G.; Cahill, Catherine F.; Mizutani, Kohei
2007-01-01
On 11 January 2006, Mount Augustine volcano in southern Alaska began erupting after 20- year repose. The Anchorage Forecast Office of the National Weather Service (NWS) issued an advisory on 28 January for Kodiak City. On 31 January, Alaska Airlines cancelled all flights to and from Anchorage after multiple advisories from the NWS for Anchorage and the surrounding region. The Alaska Volcano Observatory (AVO) had reported the onset of the continuous eruption. AVO monitors the approximately 100 active volcanoes in the Northern Pacific. Ash clouds from these volcanoes can cause serious damage to an aircraft and pose a serious threat to the local communities, and to transcontinental air traffic throughout the Arctic and sub-Arctic region. Within AVO, a dispersion model has been developed to track the dispersion of volcanic ash clouds. The model, Puff, was used operational by AVO during the Augustine eruptive period. Here, we examine the dispersion of a volcanic ash (or aerosol) cloud from Mount Augustine across Alaska from 29 January through the 2 February 2006. We present the synoptic meteorology, the Puff predictions, and measurements from aerosol samplers, laser radar (or lidar) systems, and satellites. Aerosol samplers revealed the presence of volcanic aerosols at the surface at sites where Puff predicted the ash clouds movement. Remote sensing satellite data showed the development of the ash cloud in close proximity to the volcano consistent with the Puff predictions. Two lidars showed the presence of volcanic aerosol with consistent characteristics aloft over Alaska and were capable of detecting the aerosol, even in the presence of scattered clouds and where the ash cloud is too thin/disperse to be detected by remote sensing satellite data. The lidar measurements revealed the different trajectories of ash consistent with the Puff predictions. Dispersion models provide a forecast of volcanic ash cloud movement that might be undetectable by any other means but are still a significant hazard. Validation is the key to assessing the accuracy of any predictions. The study highlights the use of multiple and complementary observations used in detecting the trajectory ash cloud, both at the surface and aloft in the atmosphere.
New Coastal Tsunami Gauges: Application at Augustine Volcano, Cook Inlet, Alaska
NASA Astrophysics Data System (ADS)
Burgy, M.; Bolton, D. K.
2006-12-01
Recent eruptive activity at Augustine Volcano and its associated tsunami threat to lower Cook Inlet pointed out the need for a quickly deployable tsunami detector which could be installed on Augustine Island's coast. The detector's purpose would be to verify tsunami generation by direct observation of the wave at the source to support tsunami warning decisions along populated coastlines. To fill this need the Tsunami Mobile Alert Real-Time (TSMART) system was developed at NOAA's West Coast/Alaska Tsunami Warning Center with support from the University of Alaska Tsunami Warning and Environmental Observatory for Alaska program (TWEAK) and the Alaska Volcano Observatory (AVO). The TSMART system consists of a pressure sensor installed as near as possible to the low tide line. The sensor is enclosed in a water-tight hypalon bag filled with propylene-glycol to prevent silt damage to the sensor and freezing. The bag is enclosed in a perforated, strong plastic pipe about 16 inches long and 8 inches in diameter enclosed at both ends for protection. The sensor is cabled to a data logger/radio/power station up to 300 feet distant. Data are transmitted to a base station and made available to the warning center in real-time through the internet. This data telemetry system can be incorporated within existing AVO and Plate Boundary Observatory networks which makes it ideal for volcano-tsunami monitoring. A TSMART network can be utilized anywhere in the world within 120 miles of an internet connection. At Augustine, two test stations were installed on the east side of the island in August 2006. The sensors were located very near the low tide limit and covered with rock, and the cable was buried to the data logger station which was located well above high tide mark. Data logger, radio, battery and other electronics are housed in an enclosure mounted to a pole which also supports an antenna and solar panel. Radio signal is transmitted to a repeater station higher up on the island which then transmits the data to a base station in Homer, Alaska. Sea level data values are transmitted every 15 seconds and displayed at the tsunami warning center in Palmer, Alaska.
Dataset for an analysis of communicative aspects of finance.
Natalya Zavyalova
2017-04-01
The article describes a step-by-step strategy for designing a universal comprehensive vision of a vast majority of financial research topics. The strategy is focused around the analysis of the retrieval results of the word processing system Serelex which is based on the semantic similarity measure. While designing a research topic, scientists usually employ their individual background. They rely in most cases on their individual assumptions and hypotheses. The strategy, introduced in the article, highlights the method of identifying components of semantic maps which can lead to a better coverage of any scientific topic under analysis. On the example of the research field of finance we show the practical and theoretical value of semantic similarity measurements, i.e., a better coverage of the problems which might be included in the scientific analysis of financial field. At the designing stage of any research scientists are not immune to an insufficient and, thus, erroneous spectrum of problems under analysis. According to the famous maxima of St. Augustine, 'Fallor ergo sum', the researchers' activities are driven along the way from one mistake to another. However, this might not be the case for the 21st century science approach. Our strategy offers an innovative methodology, according to which the number of mistakes at the initial stage of any research may be significantly reduced. The data, obtained, was used in two articles (N. Zavyalova, 2017) [7], (N. Zavyalova, 2015) [8]. The second stage of our experiment was driven towards analyzing the correlation between the language and income level of the respondents. The article contains the information about data processing.
Interferometric Synthetic Aperture radar studies of Alaska volcanoes
Lu, Zhong; Wicks, Charles W.; Dzurisin, Daniel; Power, John A.; Thatcher, Wayne R.; Masterlark, Timothy
2003-01-01
In this article, we summarize our recent InSAR studies of 13 Alaska volcanoes, including New Trident, Okmok, Akutan, Kiska, Augustine, Westdahl, Peulik, Makushin, Seguam, Shishaldin, Pavlof, Cleveland, and Korovin volcanoes.
77 FR 42425 - Amendment of Air Traffic Service (ATS) Routes in the Vicinity of Vero Beach, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-19
... Orlando, FL, 140[deg] radials; Orlando; Ocala, FL; Cross City, FL; Greenville, FL; Pecan, GA; Eufaula, AL... Virginia Key 014[deg] and Treasure, FL, 143[deg] radials; Treasure; INT Treasure 296[deg] and Orlando, FL, 162[deg] radials; Orlando; Ocala, FL; Cross City, FL; to Seminole, FL. The portion outside the United...
Augustine Band of Cahuilla Indians Energy Conservation and Options Analysis - Final Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Paul Turner
2008-07-11
The Augustine Band of Cahuilla Indians was awarded a grant through the Department of Energy First Steps program in June of 2006. The primary purpose of the grant was to enable the Tribe to develop energy conservation policies and a strategy for alternative energy resource development. All of the work contemplated by the grant agreement has been completed and the Tribe has begun implementing the resource development strategy through the construction of a 1.0 MW grid-connected photovoltaic system designed to offset a portion of the energy demand generated by current and projected land uses on the Tribe’s Reservation. Implementation ofmore » proposed energy conservation policies will proceed more deliberately as the Tribe acquires economic development experience sufficient to evaluate more systematically the interrelationships between conservation and its economic development goals.« less
Database for volcanic processes and geology of Augustine Volcano, Alaska
McIntire, Jacqueline; Ramsey, David W.; Thoms, Evan; Waitt, Richard B.; Beget, James E.
2012-01-01
This digital release contains information used to produce the geologic map published as Plate 1 in U.S. Geological Survey Professional Paper 1762 (Waitt and Begét, 2009). The main component of this digital release is a geologic map database prepared using geographic information systems (GIS) applications. This release also contains links to files to view or print the map plate, accompanying measured sections, and main report text from Professional Paper 1762. It should be noted that Augustine Volcano erupted in 2006, after the completion of the geologic mapping shown in Professional Paper 1762 and presented in this database. Information on the 2006 eruption can be found in U.S. Geological Survey Professional Paper 1769. For the most up to date information on the status of Alaska volcanoes, please refer to the U.S. Geological Survey Volcano Hazards Program website.
Adleman, Jennifer N.; Cameron, Cheryl E.; Snedigar, Seth F.; Neal, Christina A.; Wallace, Kristi L.; Power, John A.; Coombs, Michelle L.; Freymueller, Jeffrey T.
2010-01-01
The AVO Web site, with its accompanying database, is the backbone of AVO's external and internal communications. This was the first Cook Inlet volcanic eruption with a public expectation of real-time access to data, updates, and hazards information over the Internet. In March 2005, AVO improved the Web site from individual static pages to a dynamic, database-driven site. This new system provided quick and straightforward access to the latest information for (1) staff within the observatory, (2) emergency managers from State and local governments and organizations, (3) the media, and (4) the public. From mid-December 2005 through April 2006, the AVO Web site served more than 45 million Web pages and about 5.5 terabytes of data.
Cheng, Su-Li; Behrmann, Abraham; Shao, Jian-Su; Ramachandran, Bindu; Krchma, Karen; Bello Arredondo, Yoanna; Kovacs, Attila; Mead, Megan; Maxson, Robert
2014-01-01
When fed high-fat diets, male LDLR−/− mice develop obesity, hyperlipidemia, hyperglycemia, and arteriosclerotic calcification. An osteogenic Msx-Wnt regulatory program is concomitantly upregulated in the vasculature. To better understand the mechanisms of diabetic arteriosclerosis, we generated SM22-Cre;Msx1(fl/fl);Msx2(fl/fl);LDLR−/− mice, assessing the impact of Msx1+Msx2 gene deletion in vascular myofibroblast and smooth muscle cells. Aortic Msx2 and Msx1 were decreased by 95% and 34% in SM22-Cre;Msx1(fl/fl);Msx2(fl/fl);LDLR−/− animals versus Msx1(fl/fl);Msx2(fl/fl);LDLR−/− controls, respectively. Aortic calcium was reduced by 31%, and pulse wave velocity, an index of stiffness, was decreased in SM22-Cre;Msx1(fl/fl);Msx2(fl/fl);LDLR−/− mice vs. controls. Fasting blood glucose and lipids did not differ, yet SM22-Cre;Msx1(fl/fl);Msx2(fl/fl);LDLR−/− siblings became more obese. Aortic adventitial myofibroblasts from SM22-Cre;Msx1(fl/fl);Msx2(fl/fl);LDLR−/− mice exhibited reduced osteogenic gene expression and mineralizing potential with concomitant reduction in multiple Wnt genes. Sonic hedgehog (Shh) and Sca1, markers of aortic osteogenic progenitors, were also reduced, paralleling a 78% reduction in alkaline phosphatase (TNAP)–positive adventitial myofibroblasts. RNA interference revealed that although Msx1+Msx2 supports TNAP and Wnt7b expression, Msx1 selectively maintains Shh and Msx2 sustains Wnt2, Wnt5a, and Sca1 expression in aortic adventitial myofibroblast cultures. Thus, Msx1 and Msx2 support vascular mineralization by directing the osteogenic programming of aortic progenitors in diabetic arteriosclerosis. PMID:25056439
Magainin 2a - Induced Permeabilization of Phospholipid Vesicles
1991-01-02
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(EGS) Geothermal resource assessment High pressure, high temperature reaction systems Research Interests EGS demonstration and deployment Advanced drilling systems research Thermodynamics and process Phenomenological Experimental Demonstrations to Quantitative Understanding." Journal of Supercritical Fluids
Human Space Flight Plans Committee
2009-08-12
Former astronaut Dr. Sally Ride, left, confers with Norman Augustine, chair, prior to the start of the final meeting of the Human Space Flight Review Committee, Wednesday, Aug. 12, 2009, in Washington. Photo Credit: (NASA/Paul E. Alers)
Human Space Flight Plans Committee
2009-12-07
Former astronaut Dr. Sally Ride, left, confers with Norman Augustine, chair, prior to the start of the final meeting of the Human Space Flight Review Committee, Wednesday, Aug. 12, 2009, in Washington. Photo Credit: (NASA/Paul E. Alers)
75 FR 70917 - Environmental Impacts Statements; Notice Of Availability
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-19
... Augustin 651-290-5378. Amended Notices EIS No. 20100386, Draft EIS, BLM, UT, Uinta Basin Natural Gas Development Project, To Develop Oil and Natural Gas Resources within the Monument Butte-Red Wash and West...
Cheng, Su-Li; Behrmann, Abraham; Shao, Jian-Su; Ramachandran, Bindu; Krchma, Karen; Bello Arredondo, Yoanna; Kovacs, Attila; Mead, Megan; Maxson, Robert; Towler, Dwight A
2014-12-01
When fed high-fat diets, male LDLR(-/-) mice develop obesity, hyperlipidemia, hyperglycemia, and arteriosclerotic calcification. An osteogenic Msx-Wnt regulatory program is concomitantly upregulated in the vasculature. To better understand the mechanisms of diabetic arteriosclerosis, we generated SM22-Cre;Msx1(fl/fl);Msx2(fl/fl);LDLR(-/-) mice, assessing the impact of Msx1+Msx2 gene deletion in vascular myofibroblast and smooth muscle cells. Aortic Msx2 and Msx1 were decreased by 95% and 34% in SM22-Cre;Msx1(fl/fl);Msx2(fl/fl);LDLR(-/-) animals versus Msx1(fl/fl);Msx2(fl/fl);LDLR(-/-) controls, respectively. Aortic calcium was reduced by 31%, and pulse wave velocity, an index of stiffness, was decreased in SM22-Cre;Msx1(fl/fl);Msx2(fl/fl);LDLR(-/-) mice vs. controls. Fasting blood glucose and lipids did not differ, yet SM22-Cre;Msx1(fl/fl);Msx2(fl/fl);LDLR(-/-) siblings became more obese. Aortic adventitial myofibroblasts from SM22-Cre;Msx1(fl/fl);Msx2(fl/fl);LDLR(-/-) mice exhibited reduced osteogenic gene expression and mineralizing potential with concomitant reduction in multiple Wnt genes. Sonic hedgehog (Shh) and Sca1, markers of aortic osteogenic progenitors, were also reduced, paralleling a 78% reduction in alkaline phosphatase (TNAP)-positive adventitial myofibroblasts. RNA interference revealed that although Msx1+Msx2 supports TNAP and Wnt7b expression, Msx1 selectively maintains Shh and Msx2 sustains Wnt2, Wnt5a, and Sca1 expression in aortic adventitial myofibroblast cultures. Thus, Msx1 and Msx2 support vascular mineralization by directing the osteogenic programming of aortic progenitors in diabetic arteriosclerosis. © 2014 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.
NASA Astrophysics Data System (ADS)
Adleman, J. N.
2006-12-01
The 2006 eruption of Augustine Volcano provided the Alaska Volcano Observatory (AVO) with an opportunity to test its newly renovated Operations Center (Ops) at the Alaska Science Center in Anchorage. Because of the demand for interagency operations and public communication, Ops became the hub of Augustine monitoring activity, twenty-four hours a day, seven days a week, from January 10 through May 19, 2006. During this time, Ops was staffed by 17 USGS AVO staff, and over two dozen Fairbanks-based AVO staff from the Alaska Department of Geological and Geophysical Surveys and the University of Alaska Fairbanks Geophysical Institute and USGS Volcano Hazards Program staff from outside Alaska. This group engaged in communicating with the public, media, and other responding agencies throughout the eruption. Before and during the eruption, reference sheets - ;including daily talking - were created, vetted, and distributed to prepare staff for questions about the volcano. These resources were compiled into a binder stationed at each Ops phone and available through the AVO computer network. In this way, AVO was able to provide a comprehensive, uniform, and timely response to callers and emails at all three of its cooperative organizations statewide. AVO was proactive in scheduling an Information Scientist for interviews on-site with Anchorage television stations and newspapers several times a week. Scientists available, willing, and able to speak clearly about the current activity were crucial to AVO's response. On January 19, 2006, two public meetings were held in Homer, 120 kilometers northeast of Augustine Volcano. AVO, the West Coast Alaska Tsunami Warning Center, and the Kenai Peninsula Borough Office of Emergency Management gave brief presentations explaining their roles in eruption response. Representatives from several local, state, and federal agencies were also available. In addition to communicating with the public by daily media interviews and phone calls to Ops, all activity reports, images, and selected data streams were posted in near real time on the AVO public website. Hundreds of emails were answered. The AVO website quickly became highly organized and the most up-to-date and comprehensive place for anyone with internet access to learn about the eruption and AVO's response. This was the first such organized response of AVO and may be the outgrowth of increased expectations of AVO by the public. From November 28, 2005, through May 16, 2006, staff logged and answered approximately 400 phone calls and 1000 emails about Augustine. AVO's interagency response plan and relationships with other key agencies helped in responding to requests from the media and the public for a wide variety of information. However, the most frequent questions from callers were about ash fall advisories and what to do in the event of an ash fall. This highlighted the need to produce coordinated, co-agency reporting of ash fall potential and recommended preparation.
[Towards an evolution of sexual ethics].
Dominga Trapasso, R
1991-01-01
The position of the Catholic Church on contraception is well known. It has been reiterated in travels of Pope John II to such countries as Kenya, where the average woman has 8.1 children, and India, a country with 700 million inhabitants. The Church's stagnant position on family planning is very different from its more progressive pronouncements on socioeconomic topics in general. The Pope has spoken out against apartheid, hunger, poverty, colonialism, militarism, and excessive external debt. The position of the Church regarding women and the use of modern contraception in contrast has been closed and intransigent. The sexual ethics of the Catholic Church has continued under the influence of the thought of Saint Augustine, who was born in 354, for over 1500 years. The official church position on sexual ethics and procreation is based on Saint Augustine's dictum that sexual relations, even with the legitimate wife, are illicit when an attempt is made to impede conception. In Saint Augustine's thought, sexuality and procreation were inseparable; sexual desire was seen as an animal tendency but justifiable when and only when the sex act had procreation as its finality. Augustine's idea on sexuality were adapted and incorporated into the Magisterium---the body of teachings and declarations of popes and bishops intended to regulate the behavior of Church members. The Magisterium represents the official Church position but is not regarded as infallible; its pronouncements can be modified and corrected. The Magisterium holds that matrimony is indissoluble and that the sex act should occur only within matrimony. Procreation is the finality of the sex act, and attempts to prevent procreation by direct intervention to prevent conception are illicit. It must be recognized that the obligatory linking of sex and procreation has been a source of social and sexual control over women. Although the thought of Augustine has dominated, there have been signs of change in the past 50 years. The 1930 letter of Pope Pius XI, Casti Conubi, largely reiterated the traditional teachings but also declared that the happiness of the couple, not just procreation, is a finality of marriage. In 1951, Pope Pius XII in a famous address to a group of nurses and obstetricians recognized the possibility of spacing births by the rhythm method, which was regarded as "natural" because it did not impede procreation in a direct form. In 1963, during the 2nd Vatican Council, Pope John XXIII created a commission to study the question of birth control. Its 68 members were unable to agree and presented 2 reports to Pope Paul VI, who adopted the minority position, held by only 4 members, that maintained the traditional Church position but without proposing theological reasons. The 1968 letter Humanae Vitae once again declared sex and procreation inseparable and all attempts at birth control illicit. It is time for a new ethics that recognizes sex as a vital and marvelous dimension of sexuality.
1993-08-01
Inc., 445 Pineda C. Melbourne, FL 32940 Contract No. F19628-91-C-0172 OBJECTIVE The framework for a system for automatic global seismic event...placedinsde hoiona tunlwihi meddi ooeeu lsi mees X5 o w ie f h unl( n 10 mee ai) ah aito atrEahptensda o n tesm sclbtwhaspre manfcto atr * 40 U * I 1 9w...34" - a o * a • * ao * U°o " - x3 20 ’x i, 4, * . St. at l mees n o w ie fttne 5 an10mtradi. ahrdaio pten O is calculated at a semi-circular receiver
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. Senate Committee on Labor and Human Resources.
This document contains the text of a Senate hearing on crimes against the elderly. Senator Paula Hawkins examines funding for day care of the elderly and discusses the crime of elder abuse and other crimes against the elderly. Two victims of abuse testify about their abuse, a victim of violent crime describes her victimization, and a…
Design Considerations for IAP Charts: Approach Course Track and Communication Frequencies
1991-08-01
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The reawakening of Alaska's Augustine volcano
Power, John A.; Nye, Christopher J.; Coombs, Michelle L.; Wessels, Rick L.; Cervelli, Peter F.; Dehn, Jon; Wallace, Kristi L.; Freymueller, Jeffrey T.; Doukas, Michael P.
2006-01-01
The eruption was heralded by eight months of increasing seismicity, deformation, gas emission, and small phreatic eruptions, the latter consisting of explosions of steam and debris caused by heating and expansion of groundwater due to an underlying heat source.
Volcanic ash plume identification using polarization lidar: Augustine eruption, Alaska
Sassen, Kenneth; Zhu, Jiang; Webley, Peter W.; Dean, K.; Cobb, Patrick
2007-01-01
During mid January to early February 2006, a series of explosive eruptions occurred at the Augustine volcanic island off the southern coast of Alaska. By early February a plume of volcanic ash was transported northward into the interior of Alaska. Satellite imagery and Puff volcanic ash transport model predictions confirm that the aerosol plume passed over a polarization lidar (0.694 mm wavelength) site at the Arctic Facility for Atmospheric Remote Sensing at the University of Alaska Fairbanks. For the first time, lidar linear depolarization ratios of 0.10 – 0.15 were measured in a fresh tropospheric volcanic plume, demonstrating that the nonspherical glass and mineral particles typical of volcanic eruptions generate strong laser depolarization. Thus, polarization lidars can identify the volcanic ash plumes that pose a threat to jet air traffic from the ground, aircraft, or potentially from Earth orbit.
1986 eruption of Augustine Volcano: Public safety response by Alaskan volcanologists
NASA Astrophysics Data System (ADS)
Kienle, J.; Davies, J. N.; Miller, T. P.; Yount, M. E.
Although, in a general sense, all scientific work on hazardous natural phenomena such as weather, earthquakes, and volcanic eruptions can advance the public safely, we wish to describe some specific actions that were motivated by direct considerations of safety. These kinds of actions are normally at the fringes of scientific research and become important only during some crisis; in this instance, the crisis was the eruption on March 27, 1986, of Augustine Volcano (Figure 1). The agencies involved were the Geophysical Institute of the University of Alaska (UAGI), the Division of Geological and Geophysical Surveys of the State of Alaska (DGGS), and the Alaska Branch of the United States Geological Survey (USGS). The central theme of our mutual effort during the crisis was to communicate to response agencies and the public, in the most meaningful way possible, a prediction of what could happen next and how it would affect the public.
Jung, Seungyoun; Smith-Warner, Stephanie A; Willett, Walter C; Wang, Molin; Wu, Tianying; Jensen, Majken; Hankinson, Susan E; Eliassen, A Heather
2016-09-21
Healthy diets may lower oxidative stress and risk of chronic diseases. However, no previous studies examined associations between diet and fluorescent oxidation products (FlOP), a global marker of oxidative stress. We evaluated associations between healthy eating patterns (Alternative Healthy Eating Index (AHEI), Dietary Approach to Stop Hypertension (DASH), and Alternate Mediterranean Diet (aMED)) and FlOP, measured at three excitation/emission wavelengths (FlOP_360, FlOP_320, FlOP_400) from 2021 blood samples collected from 1688 women within the Nurses' Health Study. AHEI, DASH, and aMED scores were significantly positively associated with FlOP_360 and FlOP_320 concentrations ( p -trend ≤ 0.04), but not associated with FlOP_400. Among specific food groups that contribute to these diet scores, significantly positive associations were observed with legumes and vegetables for FlOP_360, vegetables and fruits for FlOP_320, and legumes and alcohol for FlOP_400. Inverse associations were observed with nuts, sweets or desserts, and olive oil for FlOP_360, nuts for FlOP_320 and sweets or desserts for FlOP_400 (all p -trend ≤ 0.05). However, FlOP variation due to diet was small compared to overall FlOP variation. In conclusion, AHEI, DASH, and aMED scores were unexpectedly positively, but weakly, associated with FlOP_360 and FlOP_320. However, these findings should be interpreted cautiously as the determinants of FlOP concentrations are not fully understood.
Geologic framework of lower Cook Inlet, Alaska
Fisher, M.A.; Magoon, L.B.
1978-01-01
Three seismic reflectors are present throughout the lower Cook Inlet basin and can be correlated with onshore geologic features. The reflections come from unconformities at the base of the Tertiary sequence, at the base of Upper Cretaceous rocks, and near the base of Upper Jurassic strata. A contour map of the deepest horizon shows that Mesozoic rocks are formed into a northeast-trending syncline. Along the southeast flank of the basin, the northwest-dipping Mesozoic rocks are truncated at the base of Tertiary rocks. The Augustine-Seldovia arch trends across the basin axis between Augustine Island and Seldovia. Tertiary rocks thin onto the arch from the north and south. Numerous anticlines, smaller in structural relief and breadth than the Augustine-Seldovia arch, trend northeast parallel with the basin, and intersect the arch at oblique angles. The stratigraphic record shows four cycles of sedimentation and tectonism that are bounded by three regional unconformities in lower Cook Inlet and by four thrust faults and the modern Benioff zone in flysch rocks of the Kenai Peninsula and the Gulf of Alaska. The four cycles of sedimentation are, from oldest to youngest, the early Mesozoic, late Mesozoic, early Cenozoic, and late Cenozoic. Data on organic geochemistry of the rocks from one well suggest that Middle Jurassic strata may be a source of hydrocarbons. Seismic data show that structural traps are formed by northeast-trending anticlines and by structures formed at the intersections of these anticlines with the transbasin arch. Stratigraphic traps may be formed beneath the unconformity at the base of Tertiary strata and beneath unconformities within Mesozoic strata.
Augustine Volcano, Cook Inlet, Alaska (January 31, 2006)
NASA Technical Reports Server (NTRS)
2006-01-01
Since last spring, the U.S. Geological Survey's Alaska Volcano Observatory (AVO) has detected increasing volcanic unrest at Augustine Volcano in Cook Inlet, Alaska near Anchorage. Based on all available monitoring data, AVO regards that an eruption similar to 1976 and 1986 is the most probable outcome. During January, activity has been episodic, and characterized by emission of steam and ash plumes, rising to altitudes in excess of 9,000 m (30,000 ft), and posing hazards to aircraft in the vicinity. In the last week, volcanic flows have been seen on the volcano's flanks. An ASTER thermal image was acquired at night at 22:50 AST on January 31, 2006, during an eruptive phase of Augustine. The image shows three volcanic flows down the north flank of Augustine as white (hot) areas. The eruption plume spreads out to the east in a cone shape: it appears dark blue over the summit because it is cold and water ice dominates the composition; further downwind a change to orange color indicates that the plume is thinning and the signal is dominated by the presence of ash. ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products. The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance. The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate. Size: 54 by 51.9 km (33.5 by 32.1 miles) Location: 59.3 deg. North latitude, 153.4 deg. West longitude Orientation: north to top Resolution: 90 m ASTER Date Acquired: January 31, 2006KINARE, Arun S; CHINCHWADKAR, Manoj C; NATEKAR, Asit S; COYAJI, Kurus J; WILLS, Andrew K; JOGLEKAR, Charudatta V; YAJNIK, Chittaranjan S; FALL, Caroline HD
2012-01-01
Objective To describe fetal size in a rural Indian population and compare it with European and urban Indian populations using ultrasound. Methods Participants were from the Pune Maternal Nutrition Study, India. Fetal growth curves were constructed from serial ultrasound scans at ~18, 30 and 36 weeks gestation in 653 singleton pregnancies. Measurements included femur length (FL) and abdominal circumference (AC), and biparietal diameter (BPD) and occipito-frontal diameter (OFD) from which head circumference (HC) was estimated. Measurements were compared with data from a large population-based study in France and a study of urban mothers in Vellore, South India. Results Fetal AC and BPD were smaller than the French reference at 18 weeks gestation (−1.38 SD and −1.30 SD respectively), while FL and HC were more comparable (−0.77 SD and −0.59 SD). The deficit remained similar at 36 weeks for AC (−0.97 SD), FL (−0.43 SD) and HC (−0.52 SD) and increased for BPD (−2.3 SD). Ultrasound at 18 weeks under-estimated gestational age, compared with LMP date, by a median of −1.4 (IQR −4.6, 1.8) days. The Pune fetuses were smaller, even at the 1st scan, than the urban Vellore sample. Conclusions Fetal size is smaller in a rural Indian population than in European or urban Indian populations, even in mid pregnancy. The deficit varied for different fetal measurements; it was greatest for abdominal circumference and biparietal diameter and least for femur length and head circumference. PMID:20103791
[Antoine Augustin Parmentier (1737-1813): military pharmacist, humanist and scholar].
Ricordel, Ivan
2014-10-01
From "Frison" pharmacy of his district, Sainte Croix square in Montdidier, where he learned the trade of a pharmacist when he was 15 years old, to the General Inspectorate of the health service of Army responsability he helds from the 1st Germinal, Year IV until his death, Antoine Augustin Parmentier was both an humanist and anerudite scholar even if often, posterity and legend reduce his image only to that of"the inventor" of the most common Solanaceae. His work, more than 189 publications, and his innovative ideas, made advancing scientific knowledge including food chemistry and nutritional health but also in various other areas: blood analysis, preparation of drugs...Better known as "Fighter of the only war that has a biological and moral justification: the war against hunger" as Jose Castro President of the FAO in 1954 recalls, less is known about the excep- tional longevity, 56 years, and riches of his military pharmacist career during which he participated in 17 campaigns and he was captured 5 times. Apothecary "sub-help" of the army of Hanover in 1757, he became apothecary "gagnant maitrise" in 1766 and transiently apothecary Major at the "Hotel des Invalides", then Royal Censor, chief pharmacist of Geneva Army, and Board Member Health to the Minister of War in 1788 and then again from 1792 to 1813. In 1796, he was charged with five other inspectors of the reorganization of the health service. Outstanding organizer, he simplifies and deeply streamlines, especially in the pharmaceutical field, evidenced by its pharmaceutical form for the use of military hospitals of the French Republic in 1793. He left his mark for a long time in the military health Service. Member of the general council of civilians hospices of Paris, he is responsible for organizing the central hospital pharmacy, which led him to publish in 1811 the pharmaceutical code for the use of civilian hospitals, relief at home and infirmaries of prison. Benefactor of mankind, but also recognized scholar, the Academy of Sciences made him one of its members in 1795. Parmentier was in 1803, the first president of the Society of Pharmacy of Paris who became the National Academy in October 1979. He died on December 17, 1813 leaving a considerable body of work.
Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure.
Bartram, Malte P; Amendola, Elena; Benzing, Thomas; Schermer, Bernhard; de Vita, Gabriella; Müller, Roman-Ulrich
2016-04-18
Non-coding RNAs have gained increasing attention during the last decade. The first large group of non-coding RNAs to be characterized systematically starting at the beginning of the 21st century were small oligonucleotides--the so-called microRNAs (miRNAs). By now we have learnt that microRNAs are indispensable for most biological processes including organogenesis and maintenance of organ structure and function. The role of microRNAs has been studied extensively in the development of a number of organs, so far most studies focussed on e.g. the heart or the brain whilst the role of microRNAs in the development and maintenance of complex epithelial organs is less well understood. Furthermore most analyses regarding microRNA function in epithelial organs employed conditional knockout mouse models of the RNAse III Dicer to abrogate microRNA biogenesis. However, there is increasing evidence for Dicer to have multiple functions independent from microRNA maturation. Therefore Dicer independent models are needed to gain further insight into the complex biology of miRNA dependent processes. Here we analyze the contribution of microRNA-dependent transcriptional control in Pax8-expressing epithelial cells. Pax8 is a transcription factor that is crucial to the development of epithelial organs. The miRNA machinery was disrupted by crossing conditional DiGeorge syndrome critical region 8 (Dgcr8) fl/fl mice to Pax8Cre mice. The Dgcr8/Drosha complex processes pri-miRNAs in the nucleus before they are exported as pre-miRNAs for further maturation by Dicer in the cytoplasm. Dgcr8 fl/fl; Pax8Cre+ knockout mice died prematurely, developed massive hypothyroidism and end stage renal disease due to a loss of miRNAs in Pax8 expressing tissue. Pax8Cre-mediated conditional loss of DiGeorge syndrome critical region 8 (Dgcr8), an essential component of the nuclear machinery that is required for microRNA biogenesis, resulted in severe hypothyroidism, massively reduced body weight and ultimately led to renal failure and death of the animals. These data provide further insight into the importance of miRNAs in organ homeostasis using a Dicer independent model.
30 CFR 7.86 - Test equipment and specifications.
Code of Federal Regulations, 2012 CFR
2012-07-01
...) Filters—F1, F2, F3, and F4; (ii) Flowmeters—FL1, FL2, FL3, FL4, FL5, FL6, and FL7; (iii) Upstream Gauges... equivalent results. The components are designated as follows— (i) Filters—F1, F2, F3, and F4; (ii) Flowmeters... exhaust pipe up to the filter holder, which are in contact with raw and diluted exhaust gas, shall be...
Organization - NOAA's National Weather Service
Virginia Charleston Alabama Birmingham Huntsville Mobile Arkansas Little Rock Florida Jacksonville Key West Mobile/Pensacola Tallahassee, FL Key West, FL Miami-South Florida, FL Tampa Bay, FL Melbourne, FL
15. Historic American Buildings Survey E. W. Russell, Photographer, March ...
15. Historic American Buildings Survey E. W. Russell, Photographer, March 15, 1936 BLINDS ON FRENCH TYPE DOOR OPENING ON W. REAR PORCH, 2nd STORY, N. SIDE APARTMENT - Augustine Ottenstein House, 207-209 North Jackson Street, Mobile, Mobile County, AL
1976-06-01
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Ein Konzept für den energieeffizienten Betrieb von Mobilfunknetzen
NASA Astrophysics Data System (ADS)
Bayer, N.; von Hugo, D.
2015-11-01
Der flächendeckende Betrieb mehrerer Mobilfunknetze unterschiedlicher Technologie in einem Land sorgt aufgrund der ständigen Bereithaltung von Übertragungskapazität für Dienste mit zunehmend höherem Datenvolumenbedarf für einen erheblichen Energieverbrauch. Das Forschungsförderungsprojekt ComGreen hat sich zur Aufgabe gesetzt, durch lastadaptiven Betrieb und intelligente dynamische Rekonfiguration des Funkzugangsnetzes zur Energieeinsparung beizutragen. Konzept, Herausforderungen, ausgewählte Ergebnisse von Simulationen und prototypischem Betrieb werden ebenso wie typische Erwartungswerte des künftigen Energieverbrauchs im Mobilfunkbereich vorgestellt. Sowohl Berechnungen als auch Messungen zeigen, dass durch kontext-basierte dynamische Rekonfiguration von zellularen Funknetzen Energieeinsparungen im Bereich von 25-40 % ermöglicht werden.
Kramer, Benjamin J; Davis, Timothy W; Meyer, Kevin A; Rosen, Barry H; Goleski, Jennifer A; Dick, Gregory J; Oh, Genesok; Gobler, Christopher J
2018-01-01
Lake Okeechobee, FL, USA, has been subjected to intensifying cyanobacterial blooms that can spread to the adjacent St. Lucie River and Estuary via natural and anthropogenically-induced flooding events. In July 2016, a large, toxic cyanobacterial bloom occurred in Lake Okeechobee and throughout the St. Lucie River and Estuary, leading Florida to declare a state of emergency. This study reports on measurements and nutrient amendment experiments performed in this freshwater-estuarine ecosystem (salinity 0-25 PSU) during and after the bloom. In July, all sites along the bloom exhibited dissolved inorganic nitrogen-to-phosphorus ratios < 6, while Microcystis dominated (> 95%) phytoplankton inventories from the lake to the central part of the estuary. Chlorophyll a and microcystin concentrations peaked (100 and 34 μg L-1, respectively) within Lake Okeechobee and decreased eastwards. Metagenomic analyses indicated that genes associated with the production of microcystin (mcyE) and the algal neurotoxin saxitoxin (sxtA) originated from Microcystis and multiple diazotrophic genera, respectively. There were highly significant correlations between levels of total nitrogen, microcystin, and microcystin synthesis gene abundance across all surveyed sites (p < 0.001), suggesting high levels of nitrogen supported the production of microcystin during this event. Consistent with this, experiments performed with low salinity water from the St. Lucie River during the event indicated that algal biomass was nitrogen-limited. In the fall, densities of Microcystis and concentrations of microcystin were significantly lower, green algae co-dominated with cyanobacteria, and multiple algal groups displayed nitrogen-limitation. These results indicate that monitoring and regulatory strategies in Lake Okeechobee and the St. Lucie River and Estuary should consider managing loads of nitrogen to control future algal and microcystin-producing cyanobacterial blooms.
Doukas, Michael P.; McGee, Kenneth A.
2007-01-01
INTRODUCTION This report presents gas emission rates from data collected during numerous airborne plume-measurement flights at Alaskan volcanoes since 1995. These flights began in about 1990 as means to establish baseline values of volcanic gas emissions during periods of quiescence and to identify anomalous levels of degassing that might signal the beginning of unrest. The primary goal was to make systematic measurements at the major volcanic centers around the Cook Inlet on at least an annual basis, and more frequently during periods of unrest and eruption. A secondary goal was to measure emissions at selected volcanoes on the Alaska Peninsula. While the goals were not necessarily met in all cases due to weather, funding, or the availability of suitable aircraft, a rich dataset of quality measurements is the legacy of this continuing effort. An earlier report (Doukas, 1995) presented data for the period from 1990 through 1994 and the current report provides data through 2006. This report contains all of the available measurements for SO2, CO2, and H2S emission rates in Alaska determined by the U. S. Geological Survey from 1995 through 2006; airborne measurements for H2S began in Alaska in 2001. The results presented here are from Cook Inlet volcanoes at Spurr, Crater Peak, Redoubt, Iliamna, and Augustine and cover periods of unrest at Iliamna (1996) and Spurr (2004-2006) as well as the 2006 eruption of Augustine. Additional sporadic measurements at volcanoes on the Alaska Peninsula (Douglas, Martin, Mageik, Griggs, Veniaminof, Ukinrek Maars, Peulik, and Fourpeaked during its 2006 unrest) are also reported here.
Petersen, Tanja; De Angelis, Silvio; Tytgat, Guy; McNutt, Stephen R.
2006-01-01
We present and interpret acoustic waveforms associated with a sequence of large explosion events that occurred during the initial stages of the 2006 eruption of Augustine Volcano, Alaska. During January 11–28, 2006, 13 large explosion events created ash-rich plumes that reached up to 14 km a.s.l., and generated atmospheric pressure waves that were recorded on scale by a microphone located at a distance of 3.2 km from the active vent. The variety of recorded waveforms included sharp N-shaped waves with durations of a few seconds, impulsive signals followed by complex codas, and extended signals with emergent character and durations up to minutes. Peak amplitudes varied between 14 and 105 Pa; inferred acoustic energies ranged between 2×108 and 4×109 J. A simple N-shaped short-duration signal recorded on January 11, 2006 was associated with the vent-opening blast that marked the beginning of the explosive eruption sequence. During the following days, waveforms with impulsive onsets and extended codas accompanied the eruptive activity, which was characterized by explosion events that generated large ash clouds and pyroclastic flows along the flanks of the volcano. Continuous acoustic waveforms that lacked a clear onset were more common during this period. On January 28, 2006, the occurrence of four large explosion events marked the end of this explosive eruption phase at Augustine Volcano. After a transitional period of about two days, characterized by many small discrete bursts, the eruption changed into a stage of more sustained and less explosive activity accompanied by the renewed growth of a summit lava dome.
ERIC Educational Resources Information Center
Gönen, Ipek Kuru
2015-01-01
Reading in FL possesses certain challenges for FL readers such as difficulty in inferring underlying messages in texts and dealing with unfamiliar cultural load. All these challenges may be associated with FL learners' reading proficiency and their use of FL reading strategies especially while reading academic materials. This study aims at…
Shchepinova, Maria M; Denisov, Stepan S; Kotova, Elena A; Khailova, Ljudmila S; Knorre, Dmitry A; Korshunova, Galina A; Tashlitsky, Vadim N; Severin, Fedor F; Antonenko, Yuri N
2014-01-01
In our search for fluorescent uncouplers of oxidative phosphorylation, three esters of fluorescein, n-butyl-, n-octyl-, and n-dodecyl-oxycarbonyl-fluorescein (C4-FL, C8-FL, C12-FL) were synthesized and characterized. With increasing liposomal lipid content, the long-chain alkyl derivatives of fluorescein (C8-FL, C12-FL and commercially available C18-FL), but not C4-FL and unsubstituted fluorescein, exhibited an increase in fluorescence polarization reflecting the dye binding to liposomes. C12-FL induced proton permeability in lipid membranes, while C4-FL was inactive. In contrast to C4-FL and C18-FL, C12-FL and C8-FL increased the respiration rate and decreased the membrane potential of isolated rat liver mitochondria with half-maximal effective concentrations of 700nM and 300nM, respectively. The effect of Cn-FL on the respiration correlated with that on proton permeability of the inner mitochondrial membrane, as measured by induction of mitochondria swelling in the potassium acetate medium. Binding of C8-FL to mitochondria depended on their energization, which was apparently associated with pH gradient generation across the inner mitochondrial membrane in the presence of a respiratory substrate. In wild-type yeast cells, C12-FL localized predominantly in plasma membrane, whereas in AD1-8 mutants lacking MDR pumps, it stained cytoplasmic organelles with some preference for mitochondria. Fluorescent uncouplers can be useful as a tool for determining their localization in a cell or distribution between different tissues in a living animal by fluorescent microscopy. © 2013.
Exploring the Origin of Blue and Ultraviolet Fluorescence in Graphene Oxide.
Kozawa, Daichi; Miyauchi, Yuhei; Mouri, Shinichiro; Matsuda, Kazunari
2013-06-20
We studied the fluorescence (FL) properties of highly exfoliated graphene oxide (GO) in aqueous solution using continuous-wave and time-resolved FL spectroscopy. The FL spectra of highly exfoliated GO showed two distinct peaks at ∼440 (blue) and ∼300 nm [ultraviolet (UV)]. The FL of GO in the UV region at ∼300 nm was observed for the first time. The average FL lifetimes of the emission peaks at ∼440 and ∼300 nm are 8-13 and 6-8 ns, respectively. The experimentally observed peak wavelengths of pH-dependent FL, FL excitation spectra, and the FL lifetimes are nearly coincident with those of aromatic compounds bound with oxygen functional groups, which suggests that the FL comes from sp(2) fragments consisting of small numbers of aromatic rings with oxygen functional groups acting as FL centers in the GO.
Doctors and torture: the police surgeon.
Burges, S H
1980-09-01
Much has been written by many distinguished persons about the philosophical, religious and ethical considerations of doctors and their involvement with torture. What follows will not have the erudition or authority of the likes of St Augustine, Mahatma Gandi, Schopenhauer or Thomas Paine. It represents the views of a very ordinary person; a presumption defended by the submission that many very ordinary persons have been, and will be, instruments for effecting, assisting or condoning the physical or mental anguish of others. As practitioners of medicine, we are particularly vulnerable, since our particular knowledge and our privileged position may be so easily abused--to the detriment of others. Those of us who practice clinical forensic medicine have even greater responsibility by virtue of our daily contact with the enforcement of law, criminal procedure, and the machinations of the judiciary. We are thus particularly well placed to monitor, encourage or discourage the occurrence of evil practices within the community. It is imperative, therefore, that the ordinary doctor should be cognisant of, and be party to, a code of conduct formulated by his peers and having reference to his obligations as a citizen, and doctor, and to his ability to manipulate human activity. Forensic physicians have further discretionary powers as arbiters in the marriage of the art and ethics of healing with the principles and practice of justice.
Pinto-Correia, Clara; Monteiro, João Lourenço
2014-03-01
In 1756, while he was regent of the Faculté de Médecine in Paris, Charles-Augustin Vandermonde published his Essai sur la Manière de Perfectionner l'Espèce Humaine. This treatise was situated within the French-led medical movement of meliorism, meant to increase public health by boosting the medical arrangement of marriages from all strata of society. What made Vandermonde different from his colleagues is that he was not just looking for a way to improve the health of society: he was also proposing a series of measures meant to increase the beauty of humankind. And, for the first time in the history of European medicine, he advocated mixed-race couplings as a means to obtain the best results. This latter development is so unexpected in the global setting of the Enlightenment that we could arguably hail Vandermonde as the founding father of what Michel Foucault later called 'biopolitique'. Copyright © 2013 Elsevier Ltd. All rights reserved.
Forde, Arnell S.; Dadisman, Shawn V.; Wiese, Dana S.; Phelps, Daniel C.
2013-01-01
In July (19 - 26) and November (17 - 18) of 1999, the USGS, in cooperation with the Florida Geological Survey (FGS), conducted two geophysical surveys in: (1) the Atlantic Ocean offshore of Florida's east coast from Orchid to Jupiter, FL, and (2) the Gulf of Mexico offshore of Venice, FL. This report serves as an archive of unprocessed digital boomer subbottom data, trackline maps, navigation files, GIS files, Field Activity Collection System (FACS) logs, and formal Federal Geographic Data Committee (FGDC) metadata. Filtered and gained (showing a relative increase in signal amplitude) digital images of the subbottom profiles are also provided. The USGS St. Petersburg Coastal and Marine Science Center (SPCMSC) assigns a unique identifier to each cruise or field activity. For example, identifiers 99FGS01 and 99FGS02 refer to field data collected in 1999 for cooperative work with the FGS. The numbers 01 and 02 indicate the data were collected during the first and second field activities for that project in that calendar year. Refer to http://walrus.wr.usgs.gov/infobank/programs/html/definition/activity.html for a detailed description of the method used to assign the field activity identification (ID).
Lustgarten, Michael S; Jang, Youngmok C; Liu, Yuhong; Qi, Wenbo; Qin, Yuejuan; Dahia, Patricia L; Shi, Yun; Bhattacharya, Arunabh; Muller, Florian L; Shimizu, Takahiko; Shirasawa, Takuji; Richardson, Arlan; Van Remmen, Holly
2011-06-01
In a previous study, we reported that a deficiency in MnSOD activity (approximately 80% reduction) targeted to type IIB skeletal muscle fibers was sufficient to elevate oxidative stress and to reduce muscle function in young adult mice (TnIFastCreSod2(fl/fl) mice). In this study, we used TnIFastCreSod2(fl/fl) mice to examine the effect of elevated oxidative stress on mitochondrial function and to test the hypothesis that elevated oxidative stress and decreased mitochondrial function over the lifespan of the TnIFastCreSod2(fl/fl) mice would be sufficient to accelerate muscle atrophy associated with aging. We found that mitochondrial function is reduced in both young and old TnIFastCreSod2(fl/fl) mice, when compared with control mice. Complex II activity is reduced by 47% in young and by approximately 90% in old TnIFastCreSod2(fl/fl) mice, and was found to be associated with reduced levels of the catalytic subunits for complex II, SDHA and SDHB. Complex II-linked mitochondrial respiration is reduced by approximately 70% in young TnIFastCreSod2(fl/fl) mice. Complex II-linked mitochondrial Adenosine-Tri-Phosphate (ATP) production is reduced by 39% in young and was found to be almost completely absent in old TnIFastCreSod2(fl/fl) mice. Furthermore, in old TnIFastCreSod2(fl/fl) mice, aconitase activity is almost completely abolished; mitochondrial superoxide release remains > 2-fold elevated; and oxidative damage (measured as F(2) - isoprostanes) is increased by 30% relative to age-matched controls. These data show that despite elevated skeletal muscle-specific mitochondrial oxidative stress, oxidative damage, and complex II-linked mitochondrial dysfunction, age-related muscle atrophy was not accelerated in old TnIFastCreSod2(fl/fl) mice, suggesting mitochondrial oxidative stress may not be causal for age-related muscle atrophy. No claim to original US government works. Aging Cell © 2011 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland.
Bush, Sean P.; Wen, Xianjie; Cao, Wei; Chan, Lawrence
2017-01-01
Mutations of GLI-similar 3 (GLIS3) underlie a neonatal diabetes syndrome. Genome-wide association studies revealed that GLIS3 variants are associated with both common type 1 and type 2 diabetes. Global Glis3-deficient (Glis3−/−) mice die of severe diabetes shortly after birth. GLIS3 controls islet differentiation by transactivating neurogenin 3 (Ngn3). To unravel the function of Glis3 in adults, we generated inducible global Glis3-deficient mice (Glis3fl/fl/RosaCreERT2). Tamoxifen (TAM)-treated Glis3fl/fl/RosaCreERT2 mice developed severe diabetes, which was reproduced in TAM-treated β cell–specific Glis3fl/fl/Pdx1CreERT mice, but not in TAM-treated Glis3fl/fl/MipCreERT mice. Furthermore, we generated constitutive β cell– or pancreas-specific Glis3-deficient mice using either RipCre (Glis3fl/fl/RipCre) or Pdx1Cre (Glis3fl/fl/Pdx1Cre) coexpressing mice. We observed that, remarkably, neither type of β cell– or pancreas-specific Glis3-deficient mice phenocopied the lethal neonatal diabetes observed in Glis3−/− mice. All Glis3fl/fl/RipCre mice survived to adulthood with normal glucose tolerance. Thirty percent of Glis3fl/fl/Pdx1Cre mice developed severe diabetes at 3 to 4 weeks of age, whereas 55% of them developed mild diabetes with age. In contrast to the >90% reduction of Ngn3 and near-total absence of insulin (Ins) in the embryonic pancreas of Glis3−/− mice, we found only 75%–80% reduction of Ngn3 and Ins messenger RNA or protein expression in the fetal pancreas of Glis3fl/fl/Pdx1Cre mice. The expression levels of Ngn3 and Ins correlated negatively with the extent of Cre-mediated Glis3 deletion. These mouse models are powerful tools to decipher Glis3 gene dosage effects and the role of GLIS3 mutations/variants in a spectrum of β cell dysfunction in people. PMID:27813676
Publications - GMC 304 | Alaska Division of Geological & Geophysical
DGGS GMC 304 Publication Details Title: Hard-rock geochemical data of core from the FL-001, FL-003, and . Bibliographic Reference Unknown, 2002, Hard-rock geochemical data of core from the FL-001, FL-003, and FL-004
Ohnishi, Nobuhiko; Takata, Katsuyoshi; Miyata-Takata, Tomoko; Sato, Yasuharu; Tari, Akira; Gion, Yuka; Noujima-Harada, Mai; Taniguchi, Kohei; Tabata, Tetsuya; Nagakita, Keina; Omote, Shizuma; Takahata, Hiroyuki; Iwamuro, Masaya; Okada, Hiroyuki; Maeda, Yoshinobu; Yanai, Hiroyuki; Yoshino, Tadashi
2016-11-01
Follicular lymphoma (FL) shows co-expression of B-cell lymphoma 2 (BCL2) and CD10, whereas downexpression of CD10 is occasionally experienced in gastrointestinal (GI) FL with unknown significance. Gastrointestinal FL is a rare variant of FL, and its similarity with mucosa-associated lymphoid tissue lymphoma was reported. We investigated the clinicopathological and genetic features of CD10 downexpressed (CD10 down ) GI-FL. The diagnosis of CD10 down FL was carried out with a combination of pathological and molecular analyses. The incidence of CD10 down GI-FL was shown in 35/172 (20.3%) cases, which was more frequent than nodal FL (3.5%, P < 0.001). The difference was additionally significant between GI-FL and nodal FL when the analysis was confined to primary GI-FL (55.2% vs 3.5%, P < 0.001). Compared to CD10 + GI-FL, CD10 down GI-FL significantly involved the stomach or large intestine (P = 0.015), and additionally showed the downexpression of BCL6 (P < 0.001). The follicular dendritic cell meshwork often showed a duodenal pattern in the CD10 down group (P = 0.12). Furthermore, a lymphoepithelial lesion was observed in 5/12 (40%) gastric FL cases, which indicated caution in the differentiation of mucosa-associated lymphoid tissue lymphoma. Molecular analyses were undertaken in seven cases of CD10 down GI-FL, and an identical clone was found between CD10 down follicles and CD10 + BCL2 + neoplastic follicles. In the diagnosis of cases with CD10 down BCL2 + follicles, careful examination with molecular studies should be carried out. © 2016 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.
Fluorine in the UK environment.
Fuge, R; Andrews, M J
1988-12-01
Relatively low concentrations of fluorine in drinking water (≤ 1 mg F/l) have been shown to significantly reduce the degree of dental caries in children and fluorine would also appear to have a beneficial effect on bone formation in both humans and farm animals. However, it is apparent that elevated levels of fluorine in the diet have sometimes resulted in problems of increased dental caries and of the development of bone deformities. Much of the fluorine in rocks and soils occurs in apatite and hydroxysilicate minerals, fluorite being the only relatively common rock forming mineral containing fluorine as an essential constituent.Little systematic data are available on fluorine concentrations in soils, plants and natural waters in the UK. General background soil concentrations lie in the range 200 - 400 mg F/kg. For waters the average fluorine content is low, <0.1 mg F/l.In the British Isles there are several areas where there are enhanced levels of fluorine. In the northern Pennines, Derbyshire, northeast Wales and Cornwall, fluorite occurs as a significant component of mineralisation and much fluorine has been added to the environment from mining waste dumps. Soils in northeast Wales contain up to 3,650 mg F/kg and in the northern Pennines up to 20,000 mg F/kg. Waters contain up to 2.3 mg F/l. In southwest England, the granites are generally fluorine-rich with the fluorite granites of the St Austell pluton containing as much as 1 percent fluorine. These rocks are frequently kaolinised and intensively worked as a source of china clay. Soils in the vicinity of the waste tips contain up to 3,300 mg F/kg and grasses up to 2,950 mg F/kg. Surface waters in the St Austell area contain up to 1.25 mg F/l.Atmospheric fluorine pollution around brickworks in the Peterborough and Bedford areas has resulted in fluorosis in farm animals. Other sources of atmospheric fluorine pollution are aluminium smelters, steelworks and fossil fuel burning.
Pedagogical Pleasures: Augustine in the Feminist Classroom
ERIC Educational Resources Information Center
Labinksi, Maggie A.
2017-01-01
Many feminist philosophers of education have argued that the teacher's pleasure plays an important role in the classroom. However, accessing such pleasure is often easier said than done. Given our current academic climate, how might teachers develop pedagogical practices that cultivate these delights? This article investigates the (rather…
78 FR 5562 - Additional Designations, Foreign Narcotics Kingpin Designation Act
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-25
...; nationality Mexico; Passport 03040074084 (Mexico) (individual) [SDNTK]. 2. FLORES APODACA, Augustin (a.k.a..., Colonia Canadas, Culiacan, Sinaloa 8000, Mexico; DOB 09 Jun 1964; POB Sinaloa, Mexico; Passport 040070827...; Passport 040068785 (Mexico) (individual) [SDNTK]. 4. FLORES APODACA, Panfilo; DOB 01 Jun 1969; POB Guasave...
An EarthScope Plate Boundary Observatory Progress Report
NASA Astrophysics Data System (ADS)
Jackson, M.; Anderson, G.; Blume, F.; Walls, C.; Coyle, B.; Feaux, K.; Friesen, B.; Phillips, D.; Hafner, K.; Johnson, W.; Mencin, D.; Pauk, B.; Dittmann, T.
2007-12-01
UNAVCO is building and operating the Plate Boundary Observatory (PBO), part of the NSF-funded EarthScope project to understand the structure, dynamics, and evolution of the North American continent. When complete in October 2008, the 875 GPS, 103 strain and seismic, and 28 tiltmeters stations will comprise the largest integrated geodetic and seismic network in United States and the second largest in the world. Data from the PBO network will facilitate research into plate boundary deformation with unprecedented scope and detail. As of 1 September 2007, UNAVCO had completed 680 PBO GPS stations and had upgraded 89% of the planned PBO Nucleus stations. Highlights of the past year's work include the expansion of the Alaska subnetwork to 95 continuously-operating stations, including coverage of Akutan and Augustine volcanoes and reconnaissance for future installations on Unimak Island; the installation of nine new stations on Mt. St. Helens; and the arrival of 33 permits for station installations on BLM land in Nevada. The Augustine network provided critical data on magmatic and volcanic processes associated with the 2005-2006 volcanic crisis, and has expanded to a total of 11 stations. Please visit http://pboweb.unavco.org/?pageid=3 for further information on PBO GPS network construction activities. As of September 2007, 41 PBO borehole stations had been installed and three laser strainmeter stations were operating, with a total of 60 borehole stations and 4 laser strainmeters expected by October 2007. In response to direction from the EarthScope community, UNAVCO installed a dense network of six stations along the San Jacinto Fault near Anza, California; installed three of four planned borehole strainmeter stations on Mt. St. Helens; and has densified coverage of the Parkfield area. Please visit http://pboweb.unavco.org/?pageid=8 for more information on PBO strainmeter network construction progress. The combined PBO/Nucleus GPS network provides 350 GB of raw standard rate data, with special downloads of more than 250 GB of high-rate GPS data following large earthquakes in Russia, Tonga, and Peru, as well as for community requests. The standard rate GPS data are processed routinely to generate data products including station position time series, velocity vectors, and related information, and all data products are available from the UNAVCO Facility archive. The PBO seismic network seismic network has provided 201 GB of raw data, which are available via Antelope and Earthworm from PBO and via the IRIS Data Management Center (DMC); we provide data to seismic networks operated from Caltech, UCSD, UCSB, University of Washington, and the Pacific Geosciences Center in Sidney, BC. The PBO strainmeter network has provided 93 GB of raw data, available in both raw native format and SEED format from the Northern California Earthquake Data Center and the IRIS DMC, along with higher-level products such as cleaned strain time series and related information. Please visit http://pboweb.unavco.org/gps_data and http://pboweb.unavco.org/strain_data for more information on PBO GPS and strainmeter/seismic data products, respectively.
Zha, Hongbin; Raffeld, Mark; Charboneau, Lu; Pittaluga, Stefania; Kwak, Larry W; Petricoin, Emanuel; Liotta, Lance A; Jaffe, Elaine S
2004-02-01
Overexpression of Bcl-2 protein has been known to play a role in the pathogenesis of follicular lymphoma (FL). However, 10-15% of FLs are negative for Bcl-2 by immunohistochemistry, raising the possibility that another gene product(s) may provide prosurvival signal(s). We used reverse phase protein microarray to analyze lysates of follicle center cells isolated by laser capture microdissection from: Bcl-2+ FL, Bcl-2- FL and reactive follicular hyperplasia (FH) (nine cases each group). TUNEL assay confirmed similar and reduced levels of apoptosis in Bcl-2+ FL and Bcl-2- FL, indicating the likelihood of Bcl-2-independent inhibition of apoptosis. Arrays were quantitatively analyzed with antibodies to proteins involved in the apoptotic pathway. As expected, Bcl-2 levels were up to eight-fold higher in Bcl-2+ FL than in FH and Bcl-2- FL. However, there was no difference in levels of Mcl-1 and survivin among these three groups. Bcl-X(L) showed a trend for increased expression in Bcl-2- FL as compared with Bcl-2+ FL, although the differences did not reach statistical significance (P>0.1). The increase in Bcl-X(L) may provide an alternative antiapoptotic signal in FL negative for Bcl-2 protein. Interestingly, Bax expression was higher in FL (Bcl-2+ or -) than in FH (P=0.001). Notably, phospho-Akt (Ser-473) was increased in FL (Bcl-2+ or -) (P<0.03) with increased phospho-Bad (Ser-136), as compared with levels in FH. The activation of the Akt/Bad pathway provides further evidence of prosurvival signals in FL, independent of Bcl-2 alone. These data suggest that nodal FL represents a single disease with a final common biochemical pathway.
... Organizations Birth Defect Research for Children, Inc. 976 Lake Baldwin Lane Suite 104 Orlando FL Orlando, FL ... Organizations Birth Defect Research for Children, Inc. 976 Lake Baldwin Lane Suite 104 Orlando FL Orlando, FL ...
33 CFR 80.805 - Rock Island, FL to Cape San Blas, FL.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Rock Island, FL to Cape San Blas, FL. 80.805 Section 80.805 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.805 Rock Island, FL...
33 CFR 80.805 - Rock Island, FL to Cape San Blas, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Rock Island, FL to Cape San Blas, FL. 80.805 Section 80.805 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.805 Rock Island, FL...
33 CFR 80.805 - Rock Island, FL to Cape San Blas, FL.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Rock Island, FL to Cape San Blas, FL. 80.805 Section 80.805 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.805 Rock Island, FL...
33 CFR 80.805 - Rock Island, FL to Cape San Blas, FL.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Rock Island, FL to Cape San Blas, FL. 80.805 Section 80.805 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.805 Rock Island, FL...
33 CFR 80.805 - Rock Island, FL to Cape San Blas, FL.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Rock Island, FL to Cape San Blas, FL. 80.805 Section 80.805 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.805 Rock Island, FL...
ERIC Educational Resources Information Center
Jacobs, Alan
2007-01-01
In earlier work on the hermeneutics of charity, the author explored the relevance of Augustine's insistence on charity in reading Scripture for interpreters of non-biblical texts. This article shows how one might bring such charitable reading into the classroom and reframe the teacher's task in its light. The article discusses some implications…
Research Staff | Geothermal Technologies | NREL
Position Email Phone Akar, Sertac Energy Analyst - Geothermal Sertac.Akar@nrel.gov 303-275-3725 Augustine -Geoscience Kate Young joined NREL in 2008. She has worked on analysis of geothermal exploration, drilling ) Toolkit, the Geothermal Resource Portfolio Optimization and Reporting Technique (GeoRePORT), and the
40 CFR 81.241 - Southwestern Mountains-Augustine Plains Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region (New Mexico) consists of the territorial area encompassed by the boundaries of the... Plains Intrastate Air Quality Control Region. 81.241 Section 81.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY...
40 CFR 81.241 - Southwestern Mountains-Augustine Plains Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region (New Mexico) consists of the territorial area encompassed by the boundaries of the... Plains Intrastate Air Quality Control Region. 81.241 Section 81.241 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY...
Myths of Human Sexuality in the Aging.
ERIC Educational Resources Information Center
Andrus, Charles E.
Human sexuality is discussed in terms of misconceptions about its function and the changing sexual needs of older adults. A review of history indicates that human sexuality has traditionally been connected with ideas of purity and strict importance of procreation. Judaeo-Christian ethics and the doctrine of Saint Augustine illustrate these…
A Geometric Solution of a Cournot Ogilopoly with Nonidentical Firms.
ERIC Educational Resources Information Center
Sarkar, Jyotirmoy; Gupta, Barnali; Pal, Debashis
1998-01-01
Maintains that a proper understanding of the Augustin Cournot model of imperfect competition and strategic interactions among firms in various contexts is essential for economics education. Although most models rely on complicated algebra, this one requires nothing more than high school level geometry. Includes a graphical analysis. (MJP)
Volcanic Tsunami Generation in the Aleutian Arc of Alaska
NASA Astrophysics Data System (ADS)
Waythomas, C. F.; Watts, P.
2003-12-01
Many of the worlds active volcanoes are situated on or near coastlines, and during eruptions the transfer of mass from volcano to sea is a potential source mechanism for tsunamis. Flows of granular material off of volcanoes, such as pyroclastic flow, debris avalanche, and lahar, often deliver large volumes of unconsolidated debris to the ocean that have a large potential tsunami hazard. The deposits of both hot and cold volcanic grain flows produced by eruptions of Aleutian arc volcanoes are exposed at many locations along the coastlines of the Bering Sea, North Pacific Ocean, and Cook Inlet indicating that the flows entered the sea and in some cases may have initiated tsunamis. We evaluate the process of tsunami generation by granular subaerial volcanic flows using examples from Aniakchak volcano in southwestern Alaska, and Augustine volcano in southern Cook Inlet. Evidence for far-field tsunami inundation coincident with a major caldera-forming eruption of Aniakchak volcano ca. 3.5 ka has been described and is the basis for one of our case studies. We perform a numerical simulation of the tsunami using a large volume pyroclastic flow as the source mechanism and compare our results to field measurements of tsunami deposits preserved along the north shore of Bristol Bay. Several attributes of the tsunami simulation, such as water flux and wave amplitude, are reasonable predictors of tsunami deposit thickness and generally agree with the field evidence for tsunami inundation. At Augustine volcano, geological investigations suggest that as many as 14 large volcanic-rock avalanches have reached the sea in the last 2000 years, and a debris avalanche emplaced during the 1883 eruption may have initiated a tsunami observed about 80 km east of the volcano at the village of English Bay (Nanwalek) on the coast of the southern Kenai Peninsula. By analogy with the 1883 event, previous studies concluded that tsunamis could have been generated many times in the past. If so, geological evidence of tsunamis, such as tsunami deposits on land, should be found in the area around Augustine Island. Paradoxically, unequivocal evidence for tsunami inundation has been found. Augustine Volcano is the most historically active volcano in the Cook Inlet region and a future tsunami from the volcano would have devastating consequences to villages, towns, oil-production facilities, and the fishing industry, especially if it occurred at high tide (the tidal range in this area is about 5 m). Numerical simulation experiments of tsunami generation, propagation and inundation using a subaerial debris avalanche source at Augustine volcano indicate only modest wave generation because of the shallow water surrounding the volcano (maximum water depth about 25 m). Lahar flows produced during eruptions at snow and ice clad volcanoes in the Aleutian arc also deliver copious amounts of sediment to the sea. These flows only rarely transform to subaqueous debris flows that may become tsunamigenic. However, the accumulation of loose, unconsolidated sediment on the continental shelf may lead to subaqueous debris flows and landslides if these deposits become mobilized by large earthquakes. Tsunamis produced by this mechanism could potentially reach coastlines all along the Pacific Rim. Finally, recent work in the western Aleutian Islands indicates that many of the island volcanoes in this area have experienced large-scale flank collapse. Because these volcanoes are surrounded by deep water, the tsunami hazard associated with a future sector collapse could be significant.
1980-11-01
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Marvels of illusion: illusion and perception in the art of Salvador Dali
Martinez-Conde, Susana; Conley, Dave; Hine, Hank; Kropf, Joan; Tush, Peter; Ayala, Andrea; Macknik, Stephen L.
2015-01-01
The surrealist movement aimed to blur the distinction between the real and the imagined. Such lack of a border between demonstrable truth and fantasy is perhaps most apparent in the art of Spanish painter Salvador Dali (1904–1989). Dali included numerous illusions in his artworks, with the intent to challenge the viewers' perceptions of reality and to enable them to see beyond the surface. The “Marvels of Illusion” exhibit, shown at The Dali Museum in St. Petersburg, FL., from June 14 to October 12, 2014, showcased Dali paintings, prints and sculptures centered on illusory themes. Here, we review the significance of illusions in Dali's art, focusing on the pieces displayed at the “Marvels of Illusion” exhibit. PMID:26483651
Marvels of illusion: illusion and perception in the art of Salvador Dali.
Martinez-Conde, Susana; Conley, Dave; Hine, Hank; Kropf, Joan; Tush, Peter; Ayala, Andrea; Macknik, Stephen L
2015-01-01
The surrealist movement aimed to blur the distinction between the real and the imagined. Such lack of a border between demonstrable truth and fantasy is perhaps most apparent in the art of Spanish painter Salvador Dali (1904-1989). Dali included numerous illusions in his artworks, with the intent to challenge the viewers' perceptions of reality and to enable them to see beyond the surface. The "Marvels of Illusion" exhibit, shown at The Dali Museum in St. Petersburg, FL., from June 14 to October 12, 2014, showcased Dali paintings, prints and sculptures centered on illusory themes. Here, we review the significance of illusions in Dali's art, focusing on the pieces displayed at the "Marvels of Illusion" exhibit.
1983-10-01
POSSA’P(fOPTI,TDP) * [23] E20:TOP4-T [27] POSS4T(TOP.T,TDP);TP-TOP-(NVL xTI);TOP-,LI~xTT *[28] t125:T’VN1)/-l;IS [30] -(rN=1)/ L53 [31] (P50 C1;TIS; [IV...8217ST4RTI’fl rrVE OF pTjg srvuL4TrovJ=’ [2] TO4-] [3) ’’Tr4E rNC1RE4~VT~’ L4 Tr-] * [5] ’OURA2To’v OP 5rYu&4rrOv=’ 16] TV-T0. TD -1 *[7] PosrT[O’V OF
O'Connell, Grant; Guo, Ge; Stricker, Janelle; Quinn, LeBris S; Ma, Averil; Pistilli, Emidio E
2015-02-15
Interleukin-15 (IL-15) is a putative myokine hypothesized to induce an oxidative skeletal muscle phenotype. The specific IL-15 receptor alpha subunit (IL-15Rα) has also been implicated in specifying this contractile phenotype. The purposes of this study were to determine the muscle-specific effects of IL-15Rα functional deficiency on skeletal muscle isometric contractile properties, fatigue characteristics, spontaneous cage activity, and circulating IL-15 levels in male and female mice. Muscle creatine kinase (MCK)-driven IL-15Rα knockout mice (mIl15ra(fl/fl)/Cre(+)) were generated using the Cre-loxP system. We tested the hypothesis that IL-15Rα functional deficiency in skeletal muscle would increase resistance to contraction-induced fatigue, cage activity, and circulating IL-15 levels. There was a significant effect of genotype on the fatigue curves obtained in extensor digitorum longus (EDL) muscles from female mIl15ra(fl/fl)/Cre(+) mice, such that force output was greater during the repeated contraction protocol compared with mIl15ra(fl/fl)/Cre(-) control mice. Muscles from female mIl15ra(fl/fl)/Cre(+) mice also had a twofold greater amount of the mitochondrial genome-specific COXII gene compared with muscles from mIl15ra(fl/fl)/Cre(-) control mice, indicating a greater mitochondrial density in these skeletal muscles. There was a significant effect of genotype on the twitch:tetanus ratio in EDL and soleus muscles from mIl15ra(fl/fl)/Cre(+) mice, such that the ratio was lower in these muscles compared with mIl15ra(fl/fl)/Cre(-) control mice, indicating a pro-oxidative shift in muscle phenotype. However, spontaneous cage activity was not different and IL-15 protein levels were lower in male and female mIl15ra(fl/fl)/Cre(+) mice compared with control. Collectively, these data support a direct effect of muscle IL-15Rα deficiency in altering contractile properties and fatigue characteristics in skeletal muscles.
Financial Literacy among Israeli College Students
ERIC Educational Resources Information Center
Shahrabani, Shosh
2013-01-01
In this study, responses of 574 students from two colleges in Israel were used to examine three issues: (a) financial literacy (FL) among Israeli college students, (b) gaps in FL between Jews and Arabs, and (c) factors affecting students' FL. The results showed that Israeli students exhibit a low level of FL and that FL is affected by gender,…
International estimated fetal weight standards of the INTERGROWTH-21st Project.
Stirnemann, J; Villar, J; Salomon, L J; Ohuma, E; Ruyan, P; Altman, D G; Nosten, F; Craik, R; Munim, S; Cheikh Ismail, L; Barros, F C; Lambert, A; Norris, S; Carvalho, M; Jaffer, Y A; Noble, J A; Bertino, E; Gravett, M G; Purwar, M; Victora, C G; Uauy, R; Bhutta, Z; Kennedy, S; Papageorghiou, A T
2017-04-01
Estimated fetal weight (EFW) and fetal biometry are complementary measures used to screen for fetal growth disturbances. Our aim was to provide international EFW standards to complement the INTERGROWTH-21 st Fetal Growth Standards that are available for use worldwide. Women with an accurate gestational-age assessment, who were enrolled in the prospective, international, multicenter, population-based Fetal Growth Longitudinal Study (FGLS) and INTERBIO-21 st Fetal Study (FS), two components of the INTERGROWTH-21 st Project, had ultrasound scans every 5 weeks from 9-14 weeks' until 40 weeks' gestation. At each visit, measurements of fetal head circumference (HC), biparietal diameter, occipitofrontal diameter, abdominal circumference (AC) and femur length (FL) were obtained blindly by dedicated research sonographers using standardized methods and identical ultrasound machines. Birth weight was measured within 12 h of delivery by dedicated research anthropometrists using standardized methods and identical electronic scales. Live babies without any congenital abnormality, who were born within 14 days of the last ultrasound scan, were selected for inclusion. As most births occurred at around 40 weeks' gestation, we constructed a bootstrap model selection and estimation procedure based on resampling of the complete dataset under an approximately uniform distribution of birth weight, thus enriching the sample size at extremes of fetal sizes, to achieve consistent estimates across the full range of fetal weight. We constructed reference centiles using second-degree fractional polynomial models. Of the overall population, 2404 babies were born within 14 days of the last ultrasound scan. Mean time between the last scan and birth was 7.7 (range, 0-14) days and was uniformly distributed. Birth weight was best estimated as a function of AC and HC (without FL) as log(EFW) = 5.084820 - 54.06633 × (AC/100) 3 - 95.80076 × (AC/100) 3 × log(AC/100) + 3.136370 × (HC/100), where EFW is in g and AC and HC are in cm. All other measures, gestational age, symphysis-fundus height, amniotic fluid indices and interactions between biometric measures and gestational age, were not retained in the selection process because they did not improve the prediction of EFW. Applying the formula to FGLS biometric data (n = 4231) enabled gestational age-specific EFW tables to be constructed. At term, the EFW centiles matched those of the INTERGROWTH-21 st Newborn Size Standards but, at < 37 weeks' gestation, the EFW centiles were, as expected, higher than those of babies born preterm. Comparing EFW cross-sectional values with the INTERGROWTH-21 st Preterm Postnatal Growth Standards confirmed that preterm postnatal growth is a different biological process from intrauterine growth. We provide an assessment of EFW, as an adjunct to routine ultrasound biometry, from 22 to 40 weeks' gestation. However, we strongly encourage clinicians to evaluate fetal growth using separate biometric measures such as HC and AC, as well as EFW, to avoid the minimalist approach of focusing on a single value. © 2016 Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology. © 2016 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of the International Society of Ultrasound in Obstetrics and Gynecology.
NASA Astrophysics Data System (ADS)
Nakamura, S.; Endo, M.; Yamamoto, H.; Isshiki, T.; Kimura, N.; Aoki, H.; Nojima, T.; Otani, S.; Kunii, S.
2006-12-01
We report unusual evolution of the conduction-electron state in the localized f electron system CexLa1-xB6 from normal electron state to heavy Fermi liquid (FL) state through local FL and non-FL states with increasing Ce concentration and/or with increasing magnetic field. The effective mass of quasiparticle or the coefficient A of T2 term of resistivity is found to increase divergently near the boundary between FL state and non-FL state. The features of the non-FL state are also different from those of the typical non-FL systems previously observed or theoretically predicted.
Parsi, Mansour A; Ellis, Jeffrey J; Lashner, Bret A
2008-08-01
To assess cost-effectiveness of fecal lactoferrin (FL) as the initial diagnostic approach to symptomatic patients with ileal pouch-anal anastomosis (IPAA). Four competing strategies [empiric metronidazole therapy (txMTZ), initial pouch endoscopy with biopsy (testBiop), initial FL assay followed by metronidazole therapy (testFL+MTZ), and initial FL assay followed by pouch endoscopy and biopsy (testFL+Biop)] were modeled in a decision tree. In the base-case, the average cost per patient was $241 for testFL+MTZ, $251 for txMTZ, $405 for testFL+Biop, and $431 for testBiop. The testBiop strategy had greater effectiveness compared with txMTZ but at an incremental cost of $158 per day. The txMTZ strategy was slightly more costly and minimally more effective than testFL+MTZ with an incremental cost effectiveness of just over $12 per day. However, the testFL+MTZ strategy was associated with a 31% absolute reduction in antibiotic exposure compared with the txMTZ strategy. Compared with empiric metronidazole therapy, FL before treatment with metronidazole is less costly with less exposure to antibiotics and less need for endoscopy, with only marginal decrease in effectiveness.
Yuan, Gangjun; Chen, Xin; Liu, Zhuowei; Wei, Wensu; Shu, Qinghai; Abou-Hamdan, Hussein; Jiang, Lijuan; Li, Xiangdong; Chen, Rixin; Désaubry, Laurent; Zhou, Fangjian; Xie, Dan
2018-02-07
Prohibitin 1 (PHB) is a potential target for the treatment of urothelial carcinoma of the bladder (UCB). FL3 is a newly synthesized agent that inhibits cancer cell proliferation by targeting the PHB protein; however, the effect of FL3 in UCB cells remains unexplored. FL3 was identified to be a potent inhibitor of UCB cell viability using CCK-8 (cell counting kit-8) assay. Then a series of in vitro and in vivo experiments were conducted to further demonstrate the inhibitory effect of FL3 on UCB cell proliferation and to determine the underlying mechanisms. FL3 inhibited UCB cell proliferation and growth both in vitro and in vivo. By targeting the PHB protein, FL3 inhibited the interaction of Akt and PHB as well as Akt-mediated PHB phosphorylation, which consequently decreases the localization of PHB in the mitochondria. In addition, FL3 treatment resulted in cell cycle arrest in the G2/M phase, and this inhibitory effect of FL3 could be mimicked by knockdown of PHB. Through the microarray analysis of mRNA expression after FL3 treatment and knockdown of PHB, we found that the mRNA expression of the growth arrest and DNA damage-inducible alpha (GADD45α) gene were significantly upregulated. When knocked down the expression of GADD45α, the inhibitory effect of FL3 on cell cycle was rescued, suggesting that FL3-induced cell cycle inhibition is GADD45α dependent. Our data provide that FL3 inhibits the interaction of Akt and PHB, which in turn activates the GADD45α-dependent cell cycle inhibition in the G2/M phase.
Lipophilic and hydrophilic antioxidant capacities of common foods in the United States.
Wu, Xianli; Beecher, Gary R; Holden, Joanne M; Haytowitz, David B; Gebhardt, Susan E; Prior, Ronald L
2004-06-16
Both lipophilic and hydrophilic antioxidant capacities were determined using the oxygen radical absorbance capacity (ORAC(FL)) assay with fluorescein as the fluorescent probe and 2,2'-azobis(2-amidinopropane) dihydrochloride as a peroxyl radical generator on over 100 different kinds of foods, including fruits, vegetables, nuts, dried fruits, spices, cereals, infant, and other foods. Most of the foods were collected from four different regions and during two different seasons in U.S. markets. Total phenolics of each sample were also measured using the Folin-Ciocalteu reagent. Hydrophilic ORAC(FL) values (H-ORAC(FL)) ranged from 0.87 to 2641 micromol of Trolox equivalents (TE)/g among all of the foods, whereas lipophilic ORAC(FL) values (L-ORAC(FL)) ranged from 0.07 to 1611 micromol of TE/g. Generally, L-ORAC(FL) values were <10% of the H-ORAC(FL) values except for a very few samples. Total antioxidant capacity was calculated by combining L-ORAC(FL) and H-ORAC(FL). Differences of ORAC(FL) values in fruits and vegetables from different seasons and regions were relatively large for some foods but could not be analyzed in detail because of the sampling scheme. Two different processing methods, cooking and peeling, were used on selected foods to evaluate the impact of processing on ORAC(FL). The data demonstrated that processing can have significant effects on ORAC(FL). Considering all of the foods analyzed, the relationship between TP and H-ORAC(FL) showed a very weak correlation. Total hydrophilic and lipophilic antioxidant capacity intakes were calculated to be 5558 and 166 micromol of TE/day, respectively, on the basis of data from the USDA Continuing Survey of Food Intakes by Individuals (1994-1996).
Severino, Amie; Chen, Wenling; Hakimian, Joshua K; Kieffer, Brigitte L; Gaveriaux-Ruff, Claire; Walwyn, Wendy; Marvizon, Juan Carlos
2018-04-17
The latent sensitization model of chronic pain reveals that recovery from some types of long-term hyperalgesia is an altered state in which nociceptive sensitization persists but is suppressed by the ongoing activity of analgesic receptors such as µ-opioid receptors (MORs). To determine whether these MORs are the ones present in nociceptive afferents, we bred mice expressing Cre-recombinase under the Nav1.8 channel promoter (Nav1.8cre) with MOR-floxed mice (flMOR). These Nav1.8cre/flMOR mice had reduced MOR expression in primary afferents, as revealed by quantitative PCR, in situ hybridization and immunofluorescence colocalization with the neuropeptide CGRP. We then studied the recovery from chronic pain of these mice and their flMOR littermates. When Nav1.8cre/flMOR mice were injected in the paw with complete Freund's adjuvant they developed mechanical hyperalgesia that persisted for over two months, whereas the responses of flMOR mice returned to baseline after three weeks. We then used the inverse agonist naltrexone to assess ongoing MOR activity. Naltrexone produced a robust reinstatement of hyperalgesia in control flMOR mice, but produced no effect in the Nav1.8/flMOR males and a weak reinstatement of hyperalgesia in Nav1.8/flMOR females. Naltrexone also reinstated swelling of the hind paw in flMOR mice and female Nav1.8cre/flMOR mice, but not male Nav1.8cre/flMOR mice. The MOR agonist DAMGO inhibited substance P release in flMOR mice but not Nav1.8cre/flMOR mice, demonstrating a loss of MOR function at the central terminals of primary afferents. We conclude that MORs in nociceptive afferents mediate an ongoing suppression of hyperalgesia to produce remission from chronic pain.
Joosten, Sander P J; Zeilstra, Jurrit; van Andel, Harmen; Mijnals, R Clinton; Zaunbrecher, Joost; Duivenvoorden, Annet A M; van de Wetering, Marc; Clevers, Hans; Spaargaren, Marcel; Pals, Steven T
2017-10-01
Resistance of metastatic human colorectal cancer cells to drugs that block epidermal growth factor (EGF) receptor signaling could be caused by aberrant activity of other receptor tyrosine kinases, activating overlapping signaling pathways. One of these receptor tyrosine kinases could be MET, the receptor for hepatocyte growth factor (HGF). We investigated how MET signaling, and its interaction with CD44 (a putative MET coreceptor regulated by Wnt signaling and highly expressed by intestinal stem cells [ISCs] and adenomas) affects intestinal homeostasis, regeneration, and adenoma formation in mini-gut organoids and mice. We established organoid cultures from ISCs stimulated with HGF or EGF and assessed intestinal differentiation by immunohistochemistry. Mice with total epithelial disruption of MET (Ah Cre /Met fl/fl /LacZ) or ISC-specific disruption of MET (Lgr5 Creert2 /Met fl/fl /LacZ) and control mice (Ah Cre /Met +/+ /LacZ, Lgr5 Creert2 /Met +/+ /LacZ) were exposed to 10 Gy total body irradiation; intestinal tissues were collected, and homeostasis and regeneration were assessed by immunohistochemistry. We investigated adenoma organoid expansion stimulated by HGF or EGF using adenomas derived from Lgr5 Creert2 /Met fl/fl /Apc fl/fl and Lgr5 Creert2 /Met +/+ /Apc fl/fl mice. The same mice were evaluated for adenoma prevalence and size. We also quantified adenomas in Ah Cre /Met fl/fl /Apc fl/+ mice compared with Ah Cre /Met +/+ /Apc fl/+ control mice. We studied expansion of organoids generated from crypts and adenomas, stimulated by HGF or EGF, that were derived from mice expressing different CD44 splice variants (Cd44 +/+ , Cd44 -/- , Cd44 s/s , or Cd44 v4-10/v4-10 mice). Crypts incubated with EGF or HGF expanded into self-organizing mini-guts with similar levels of efficacy and contained all differentiated cell lineages. MET-deficient mice did not have defects in intestinal homeostasis. Total body irradiation reduced numbers of proliferating crypts in Ah Cre /Met fl/fl /LacZ mice. Lgr5 Creert2 /Met fl/fl /LacZ mice had impaired regeneration of MET-deficient ISCs. Adenoma organoids stimulated with EGF or HGF expanded to almost twice the size of nonstimulated organoids. MET-deficient adenoma organoids did not respond to HGF stimulation, but did respond to EGF. ISC-specific disruption of Met (Lgr5 Creert2 /Met fl/fl /Apc fl/fl mice) caused a twofold increase in apoptosis in microadenomas, resulting in an approximately 50% reduction of microadenoma numbers and significantly reduced average adenoma size. Total epithelial disruption of Met (Ah Cre /Met fl/fl /Apc fl/+ mice) resulted in an approximate 50% reduction in (micro)adenoma numbers. Intestinal crypts from Cd44 -/- mice did not expand to the same extent as crypts from Cd44 +/+ mice on stimulation with HGF, but had the same response to EGF. The negative effect on HGF-mediated growth was overcome by expression of CD44v4-10, but not by CD44s. Similarly, HGF-mediated expansion of adenoma organoids required CD44v4-10. In studies of intestinal organoid cultures and mice with inducible deletion of MET, we found HGF receptor signaling to regulate intestinal homeostasis and regeneration, as well as adenoma formation. These activities of MET are promoted by the stem cell CD44 isoform CD44v4-10. Our findings provide rationale for targeting signaling via MET and CD44 during anti-EGF receptor therapy of patients with colorectal cancer or in patients resistant to EGF receptor inhibitors. Copyright © 2017 AGA Institute. Published by Elsevier Inc. All rights reserved.
Expansion of Countermine Lidar UAV-based System (CLUBS)
2011-09-30
analysis with environmental conditions, namely; Ft. Lauderdale, FL, Looe Key, FL, Alpena , MI, and Buttermilk Bay, MA (Figure 2). We adopt a...estimated Dstat Looe Key, FL Ft. Lauderdale, FL Alpena , MI Buttermilk Bay, MA Figure 2. Regions of interests picked for the study to...Lauderdale, FL Alpena , MI Buttermilk Bay, MA Water properties Effective Fresnel reflectivity 0.002 0.0028 0.00144 0.0005 Diffuse
The disulfide isomerase ERp57 is required for fibrin deposition in vivo.
Zhou, J; Wu, Y; Wang, L; Rauova, L; Hayes, V M; Poncz, M; Essex, D W
2014-11-01
ERp57 is required for platelet function; however, whether ERp57 contributes to fibrin generation is unknown. Using an inhibitory anti-ERp57 antibody (mAb1), Pf4-Cre/ERp57(fl/fl) mice, Tie2-Cre/ERp57(fl/fl) mice, and mutants of ERp57, we analyzed the function of ERp57 in laser-induced thrombosis. Fibrin deposition was decreased in Pf4-Cre/ERp57(fl/fl) mice, consistent with a role for platelet ERp57 in fibrin generation. Fibrin deposition was further decreased with infusion of mAb1 and in Tie2-Cre/ERp57(fl/fl) mice, consistent with endothelial cells also contributing to fibrin deposition. Infusion of eptibifatide inhibited platelet and fibrin deposition, confirming a role for platelets in fibrin deposition. Infusion of recombinant ERp57 corrected the defect in fibrin deposition but not platelet accumulation, suggesting a direct effect of ERp57 on coagulation. mAb1 inhibited thrombin generation in vitro, consistent with a requirement for ERp57 in coagulation. Platelet accumulation was decreased to similar extents in Pf4-Cre/ERp57(fl/fl) mice, Tie2-Cre/ERp57(fl/fl) mice and normal mice infused with mAb1. Infusion of completely inactivated ERp57 or ERp57 with a non-functional second active site inhibited fibrin deposition and platelet accumulation, indicating that the isomerase activity of the second active site is required for these processes. ERp57 regulates thrombosis via multiple targets. © 2014 International Society on Thrombosis and Haemostasis.
Maeshima, Akiko Miyagi; Taniguchi, Hirokazu; Suzuki, Tomotaka; Yuda, Sayako; Toyoda, Kosuke; Yamauchi, Nobuhiko; Makita, Shinichi; Fukuhara, Suguru; Munakata, Wataru; Maruyama, Dai; Kobayashi, Yukio; Saito, Yutaka; Tobinai, Kensei
2017-07-01
We compared the incidence, esophagogastroduodenoscopy (EGD) findings, and histopathologic characteristics of gastric and duodenal follicular lymphomas (FL). Of 626 FL cases, primary gastric FL and secondary gastric involvement of FL were observed in 1% and 5% of the cases, respectively, which were lower incidences than duodenal FL (10% and 9%, respectively). Gastric FL usually appeared as submucosal tumors (primary, 71%; secondary, 79%), whereas duodenal FL, as granular lesions (primary, 92%: secondary, 87%). In the granular duodenal lesions, the neoplastic follicles were located sparsely on the muscularis mucosa and could be found between villi, whereas in the stomach, similar lesions were hidden within the lamina propria, and only larger lesions such as submucosal tumors could be detected on the mucosal surface. The differences in the incidences and EGD findings were considered to be associated with structural differences of the lamina propria. Typical FL features: grades 1-2 histology, follicularity, and CD10 + and/or BCL6 + and BCL2 + were usually observed in all primary and secondary gastric and duodenal FL. Gastroduodenal and bone marrow involvement were found in 12% and 33% of the cases, respectively, and there was no significant correlation between them (P=.095). Twenty-nine cases (5%) were up-staged by gastroduodenal-positive results. In conclusion, the histopathology of gastric FL was similar to that of duodenal and nodal FL; the differences in the incidence and EGD findings between gastric and duodenal FL were considered to be associated with structural difference of the lamina propria, and EGD was useful as a staging procedure. Copyright © 2017 Elsevier Inc. All rights reserved.
McNeill, Eileen; Crabtree, Mark J.; Sahgal, Natasha; Patel, Jyoti; Chuaiphichai, Surawee; Iqbal, Asif J.; Hale, Ashley B.; Greaves, David R.; Channon, Keith M.
2015-01-01
Inducible nitric oxide synthase (iNOS) is a key enzyme in the macrophage inflammatory response, which is the source of nitric oxide (NO) that is potently induced in response to proinflammatory stimuli. However, the specific role of NO production, as distinct from iNOS induction, in macrophage inflammatory responses remains unproven. We have generated a novel mouse model with conditional deletion of Gch1, encoding GTP cyclohydrolase 1 (GTPCH), an essential enzyme in the biosynthesis of tetrahydrobiopterin (BH4) that is a required cofactor for iNOS NO production. Mice with a floxed Gch1 allele (Gch1fl/fl) were crossed with Tie2cre transgenic mice, causing Gch1 deletion in leukocytes (Gch1fl/flTie2cre). Macrophages from Gch1fl/flTie2cre mice lacked GTPCH protein and de novo biopterin biosynthesis. When activated with LPS and IFNγ, macrophages from Gch1fl/flTie2cre mice induced iNOS protein in a manner indistinguishable from wild-type controls, but produced no detectable NO, as judged by L-citrulline production, EPR spin trapping of NO, and by nitrite accumulation. Incubation of Gch1fl/flTie2cre macrophages with dihydroethidium revealed significantly increased production of superoxide in the presence of iNOS expression, and an iNOS-independent, BH4-dependent increase in other ROS species. Normal BH4 levels, nitric oxide production, and cellular redox state were restored by sepiapterin, a precursor of BH4 production by the salvage pathway, demonstrating that the effects of BH4 deficiency were reversible. Gch1fl/flTie2cre macrophages showed only minor alterations in cytokine production and normal cell migration, and minimal changes in basal gene expression. However, gene expression analysis after iNOS induction identified 78 genes that were altered between wild-type and Gch1fl/flTie2cre macrophages. Pathway analysis identified decreased NRF2 activation, with reduced induction of archetypal NRF2 genes (gclm, prdx1, gsta3, nqo1, and catalase) in BH4-deficient Gch1fl/flTie2cre macrophages. These findings identify BH4-dependent iNOS regulation and NO generation as specific requirements for NRF2-dependent responses in macrophage inflammatory activation. PMID:25451639
Towards a History of the Encyclopedia from Jerome to Isidor.
ERIC Educational Resources Information Center
Jackson, S.
1981-01-01
Traces the evolution of the idea of an encyclopedia from Jerome, who worked mainly in Caesarea in Palestine towards the end of the Roman Empire, through the work of Augustine, Martianus Capella, Boethius, and Cassiodorus Senator, to Isidor, who worked in Seville on the eve of the Carolingian Renaissance. (LLS)
The Search for Electromagnetic Induction (1820-1831). Experiment No. 20.
ERIC Educational Resources Information Center
Devons, Samuel
This paper focuses on the search for electromagnetic induction from 1820 to 1831 and the efforts by Augustin Fresnel's colleague, Andre Marie Ampere, in electric and magnetic induction. Faraday's work is discussed with excerpts from his diary on electromagnetism. A variety of different experiments by researchers including Francoise Jean Arago,…
Role of Klotho in Osteoporosis and Renal Osteodystrophy
2015-10-01
uremia induced increases in FGF23 transcription (Figure 6). VEGFa Runx2 Osx Col1a1 ALP OC 0 2 4 6 8 KL fl/fl Prx1-Cre; KL fl/fl m R N A ex pr es...week old mice revealed that Prx1cre;Klothofl/fl mice have significantly higher expression of osteoblastic and osteocytic markers such as Col1a1 , Runx2
Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation.
Zhang, Qiang; Zhang, Yaqing; Parsels, Joshua D; Lohse, Ines; Lawrence, Theodore S; Pasca di Magliano, Marina; Sun, Yi; Morgan, Meredith A
2016-11-01
Pancreatic cancers driven by KRAS mutations require additional mutations for tumor progression. The tumor suppressor FBXW7 is altered in pancreatic cancers, but its contribution to pancreatic tumorigenesis is unknown. To determine potential cooperation between Kras mutation and Fbxw7 inactivation in pancreatic tumorigenesis, we generated P48-Cre;LSL-Kras G12D ;Fbxw7 fl/fl (KFC fl/fl ) compound mice. We found that KFC fl/fl mice displayed accelerated tumorigenesis: all mice succumbed to pancreatic ductal adenocarcinoma (PDA) by 40 days of age, with PDA onset occurring by 2 weeks of age. PDA in KFC fl/fl mice was preceded by earlier onset of acinar-to-ductal metaplasia (ADM) and pancreatic intraepithelial neoplasia (PanIN) lesions, and associated with chromosomal instability and the accumulation of Fbxw7 substrates Yes-associated protein (Yap), c-Myc, and Notch. Using KFC fl/fl and FBXW7-deficient human pancreatic cancer cells, we found that Yap silencing attenuated growth promotion by Fbxw7 deletion. Our data demonstrate that Fbxw7 is a potent suppressor of Kras G12D -induced pancreatic tumorigenesis due, at least in part, to negative regulation of Yap. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.
Wang, Jiechen; Ye, Jianwei; Zheng, Xixi; Xiang, Xiaoli; Li, Changsheng; Fu, Miaomiao; Wang, Qiong; Zhang, Zhiyong; Wu, Yongrui
2017-01-01
Maize (Zea mays) floury3 (fl3) is a classic semidominant negative mutant that exhibits severe defects in the endosperm but fl3 plants otherwise appear normal. We cloned the fl3 gene and determined that it encodes a PLATZ (plant AT-rich sequence and zinc binding) protein. The mutation in fl3 resulted in an Asn-to-His replacement in the conserved PLATZ domain, creating a dominant allele. Fl3 is specifically expressed in starchy endosperm cells and regulated by genomic imprinting, which leads to the suppressed expression of fl3 when transmitted through the male, perhaps as a consequence the semidominant behavior. Yeast two-hybrid screening and bimolecular luciferase complementation experiments revealed that FL3 interacts with the RNA polymerase III subunit 53 (RPC53) and transcription factor class C 1 (TFC1), two critical factors of the RNA polymerase III (RNAPIII) transcription complex. In the fl3 endosperm, the levels of many tRNAs and 5S rRNA that are transcribed by RNAPIII are significantly reduced, suggesting that the incorrectly folded fl3 protein may impair the function of RNAPIII. The transcriptome is dramatically altered in fl3 mutants, in which the downregulated genes are primarily enriched in pathways related to translation, ribosome, misfolded protein responses, and nutrient reservoir activity. Collectively, these changes may lead to defects in endosperm development and storage reserve filling in fl3 seeds. PMID:28874509
Bedarida, Tatiana; Domingues, Alison; Baron, Stephanie; Ferreira, Chrystophe; Vibert, Francoise; Cottart, Charles-Henry; Paul, Jean-Louis; Escriou, Virginie; Bigey, Pascal; Gaussem, Pascale; Leguillier, Teddy; Nivet-Antoine, Valerie
2018-06-01
Although thioredoxin-interacting protein (TXNIP) is involved in a variety of biologic functions, the contribution of endothelial TXNIP has not been well defined. To investigate the endothelial function of TXNIP, we generated a TXNIP knockout mouse on the Cdh5-cre background (TXNIP fl/fl cdh5 cre ). Control (TXNIP fl/fl ) and TXNIP fl/fl cdh5 cre mice were fed a high protein-low carbohydrate (HP-LC) diet for 3 mo to induce metabolic stress. We found that TXNIP fl/fl and TXNIP fl/fl cdh5 cre mice on an HP-LC diet displayed impaired glucose tolerance and dyslipidemia concretizing the metabolic stress induced. We evaluated the impact of this metabolic stress on mice with reduced endothelial TXNIP expression with regard to arterial structure and function. TXNIP fl/fl cdh5 cre mice on an HP-LC diet exhibited less endothelial dysfunction than littermate mice on an HP-LC diet. These mice were protected from decreased aortic medial cell content, impaired aortic distensibility, and increased plasminogen activator inhibitor 1 secretion. This protective effect came with lower oxidative stress and lower inflammation, with a reduced NLRP3 inflammasome expression, leading to a decrease in cleaved IL-1β. We also show the major role of TXNIP in inflammation with a knockdown model, using a TXNIP-specific, small interfering RNA included in a lipoplex. These findings demonstrate a key role for endothelial TXNIP in arterial impairments induced by metabolic stress, making endothelial TXNIP a potential therapeutic target.-Bedarida, T., Domingues, A., Baron, S., Ferreira, C., Vibert, F., Cottart, C.-H., Paul, J.-L., Escriou, V., Bigey, P., Gaussem, P., Leguillier, T., Nivet-Antoine, V. Reduced endothelial thioredoxin-interacting protein protects arteries from damage induced by metabolic stress in vivo.
Radigan, Kathryn A; Morales-Nebreda, Luisa; Soberanes, Saul; Nicholson, Trevor; Nigdelioglu, Recep; Cho, Takugo; Chi, Monica; Hamanaka, Robert B; Misharin, Alexander V; Perlman, Harris; Budinger, G R Scott; Mutlu, Gökhan M
2014-01-01
During the recent H1N1 outbreak, obese patients had worsened lung injury and increased mortality. We used a murine model of influenza A pneumonia to test the hypothesis that leptin receptor deficiency might explain the enhanced mortality in obese patients. We infected wild-type, obese mice globally deficient in the leptin receptor (db/db) and non-obese mice with tissue specific deletion of the leptin receptor in the lung epithelium (SPC-Cre/LepR fl/fl) or macrophages and alveolar type II cells (LysM-Cre/Lepr fl/fl) with influenza A virus (A/WSN/33 [H1N1]) (500 and 1500 pfu/mouse) and measured mortality, viral clearance and several markers of lung injury severity. The clearance of influenza A virus from the lungs of mice was impaired in obese mice globally deficient in the leptin receptor (db/db) compared to normal weight wild-type mice. In contrast, non-obese, SP-C-Cre+/+/LepR fl/fl and LysM-Cre+/+/LepR fl/fl had improved viral clearance after influenza A infection. In obese mice, mortality was increased compared with wild-type mice, while the SP-C-Cre+/+/LepR fl/fl and LysM-Cre+/+/LepR fl/fl mice exhibited improved survival. Global loss of the leptin receptor results in reduced viral clearance and worse outcomes following influenza A infection. These findings are not the result of the loss of leptin signaling in lung epithelial cells or macrophages. Our results suggest that factors associated with obesity or with leptin signaling in non-myeloid populations such as natural killer and T cells may be associated with worsened outcomes following influenza A infection.
Yang, Shuman; Giovannucci, Edward; Bracken, Bruce; Ho, Shuk-Mei; Wu, Tianying
2015-08-14
Existing epidemiological studies of the association between oxidative stress and erectile dysfunction (ED) are sparse and inconclusive, which is likely due to cross-sectional design and small sample size. Therefore, we investigated the association between biomarkers of oxidative stress and ED in prospective setting among a relatively large sample size of men. We conducted the prospective study among 917 men ages between 47 and 80 years at the time of blood draw, which is a part of nested prospective case-control study of prostate cancer in the Health Professionals Follow-up Study. Plasma fluorescent oxidation products (FlOPs), a global biomarker for oxidative stress, were measured at three excitation/emission wavelengths (360/420 nm named as FlOP_360; 320/420 nm named as FlOP_320 and 400/475 nm named as FlOP_400). Approximately 35% of men developed ED during follow-up. We did not find an independent association between FlOP_360, FlOP_320, FlOP_400 and risk of ED in the multivariable adjusted model (Tertile 3 vs. tertile 1: odds ratio [OR] = 0.90, 95% confidence interval [CI] = 0.61-1.34, P(trend) = 0.54 for FlOP_360; OR = 0.73, 95% CI = 0.49-1.07, P(trend) = 0.27 for FlOP_320; and OR = 0.98, 95% CI = 0.66-1.45, P(trend) = 0.72 for FlOP_400). Further analysis of the association between FlOPs and ED in the fasting samples or controls only (free of prostate cancer incidence) did not change the results appreciably. Plasma FlOPs were not associated with the risk of ED, suggesting oxidative stress may not be an independent risk factor for ED.
Estimation of ligament strains and joint moments in the ankle during a supination sprain injury.
Wei, Feng; Fong, Daniel Tik-Pui; Chan, Kai-Ming; Haut, Roger C
2015-01-01
This study presents the ankle ligament strains and ankle joint moments during an accidental injury event diagnosed as a grade I anterior talofibular ligament (ATaFL) sprain. A male athlete accidentally sprained his ankle while performing a cutting motion in a laboratory setting. The kinematic data were input to a three-dimensional rigid-body foot model for simulation analyses. Maximum strains in 20 ligaments were evaluated in simulations that investigated various combinations of the reported ankle joint motions. Temporal strains in the ATaFL and the calcaneofibular ligament (CaFL) were then compared and the three-dimensional ankle joint moments were evaluated from the model. The ATaFL and CaFL were highly strained when the inversion motion was simulated (10% for ATaFL and 12% for CaFL). These ligament strains were increased significantly when either or both plantarflexion and internal rotation motions were added in a temporal fashion (up to 20% for ATaFL and 16% for CaFL). Interestingly, at the time strain peaked in the ATaFL, the plantarflexion angle was not large but apparently important. This computational simulation study suggested that an inversion moment of approximately 23 N m plus an internal rotation moment of approximately 11 N m and a small plantarflexion moment may have generated a strain of 15-20% in the ATaFL to produce a grade I ligament injury in the athlete's ankle. This injury simulation study exhibited the potentially important roles of plantarflexion and internal rotation, when combined with a large inversion motion, to produce a grade I ATaFL injury in the ankle of this athlete.
Effects of FlAsH/Tetracysteine (TC) tag on PrP proteolysis and PrPres formation by TC-scanning
Taguchi, Yuzuru; Hohsfield, Lindsay A.; Hollister, Jason R.
2014-01-01
The FlAsH/tetracysteine (FlAsH/TC) tag is a powerful tool for fluorescent labeling of proteins. However, even small tags such as FlAsH/TC could alter the behavior of the tagged proteins, especially if the insertion occurs at internal sites. Defining the influence of FlAsH/TC on nearby protein-protein interactions might aid in selecting appropriate positions for internal TC insertions and allow the exploitation of serial FlAsH/TC insertions (TC-scanning) as a probe to characterize sites of protein-protein interaction. To explore this application in the context of substrate-protease interactions, we analyzed the effect of FlAsH/TC insertions on proteolysis of cellular prion protein (PrPsen) in in vitro reactions and generation of the C1 metabolic fragment of PrPsen in live neuroblastoma cells. The influence of FlAsH/TC insertion was evaluated by TC-scanning across the cleavage sites of each protease. The results showed that FlAsH/TC inhibited protease cleavage only within limited ranges of the cleavage sites that varied from about 1 to 6 residues-wide depending on the protease, providing an estimate of the PrP residues interacting with each protease. TC-scanning was also used to probe a different type of protein-protein interaction, the conformational conversion of FlAsH-PrPsen to the prion disease-associated isoform, PrPres. PrP constructs with FlAsH/TC insertions at residues 90–96 but not 97–101 were converted to FlAsH-PrPres, identifying a boundary separating loosely versus compactly folded regions of PrPres. Our observations demonstrate that TC-scanning with the FlAsH/TC tag can be a versatile method for probing protein-protein interactions and folding processes. PMID:23943295
Yang, Shuman; Feskanich, Diane; Willett, Walter C.; Eliassen, A. Heather; Wu, Tianying
2014-01-01
Human studies suggest that oxidative stress is a risk factor for osteoporosis, but its relationship with fracture risk is poorly understood. The purpose of the present study was to investigate the association between biomarkers of oxidative stress and hip fracture in postmenopausal women. We conducted a prospective study in the Nurses’ Health Study among 996 women aged 60 years or older at baseline blood collection in 1989–1990. Plasma fluorescent oxidation products (FlOPs) were measured at three excitation/emission wavelengths (360/420 nm named as FlOP_360; 320/420 nm named as FlOP_320 and 400/475 nm named as FlOP_400). FlOPs are generated from many different pathways (lipid, protein and DNA) and reflect a global oxidation burden. FlOP assay is 10–100 times more sensitive than measurement of malondialdehyde. We used Cox proportional hazards regression model to investigate the association between baseline plasma FlOPs and risk of hip fracture, adjusting for multiple hip fracture risk factors such as age, history of osteoporosis, history of hypertension, prior fracture and smoking status. Forty four hip fractures (4.4%) were identified during the follow-up (Maximum = 23 years). In the multivariable model, the hazard ratios (HR) of hip fracture in the second and third tertiles of FlOP_320 were 2.11 (95% confidence interval [CI] = 0.88–5.10) and 2.67 (95% CI = 1.14–6.27), respectively, in comparison with the lowest tertile, and the risk increased linearly with increasing FlOP_320 (P for trend = 0.021). Neither FlOP_360 nor FlOP_400 was significantly associated with risk of hip fracture (Tertile 3 versus tertile 1: HR = 0.70, 95% CI = 0.32–1.54, P for trend = 0.386 for FlOP_360; and HR = 0.88, 95% CI = 0.40–1.96, P for trend = 0.900 for FlOP_400). In this prospective study, higher plasma FlOP_320 was an independent risk factor for hip fracture. Our results need further confirmation. PMID:24957524
Correlation between bonding structure and microstructure in fullerenelike carbon nitride thin films
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gago, R.; Abendroth, B.; Moeller, W.
2005-03-15
The bonding structure of highly ordered fullerenelike (FL) carbon nitride (CN{sub x}) thin films has been assessed by x-ray absorption near-edge spectroscopy (XANES). Samples with different degrees of FL character have been analyzed to discern spectral signatures related to the FL microstructure. The XANES spectra of FL-CN{sub x} films resemble that of graphitic CN{sub x}, evidencing the sp{sup 2} hybridization of both C and N atoms. The FL structure is achieved with the promotion of N in threefold positions over pyridinelike and cyanidelike bonding environments. In addition, the relative {pi}{sup *}/{sigma}* XANES intensity ratio at the C(1s) edge is independentmore » of the FL character, while it decreases {approx}40% at the N(1s) edge with the formation of FL arrangements. This result indicates that there is no appreciable introduction of C-sp{sup 3} hybrids with the development of FL structures and, additionally, that a different spatial localization of {pi} electrons at C and N sites takes place in curved graphitic structures. The latter has implications for the elastic properties of graphene sheets and could, as such, explain the outstanding elastic properties of FL-CN{sub x}.« less
Impact of vocal cord ultrasonography on endocrine surgery practices.
Carneiro-Pla, Denise; Solorzano, Carmen C; Wilhelm, Scott M
2016-01-01
It is common practice to perform flexible laryngoscopy (FL) to ensure true vocal cord (TVC) mobility in patients with previous neck operations or patients with suspected VC dysfunction. Vocal cord ultrasonography (VCUS) is accurate in identifying TVC paralysis. The goal of this study is to evaluate the impact of VCUS as the initial study to confirm TVC mobility in patients requiring preoperative FL. A total of 194 consecutive patients with indications for preoperative FL underwent VCUS. In group 1, 52 patients had FL regardless of the results of VCUS, whereas in group 2, 142 patients had VCUS followed by FL only when VCUS was unsatisfactory. VCUS visualized TVC/arytenoids in 164 of 194 (85%) patients. TVC visualization was more common in women (95%) and in patients without thyroid cartilage calcification (92%) (P < .0005). VCUS predicted all paralyzed TVC. In group 2, 76% of patients had adequate VCUS and avoided preoperative FL. Among 24% of patients in whom VCUS was inadequate, 16 had preoperative FL attributable to a lack of TVC visualization, 6 had abnormal TVC mobility, 11 needed additional confirmations, and 2 had previous FL for another reason. VCUS changed surgeon practices by avoiding the need for preoperative FL in the majority of patients. This noninvasive and sensitive method demonstrates TVC mobility and safely precludes preoperative FL in most patients. Copyright © 2016 Elsevier Inc. All rights reserved.
Hepatitis C virus infection is an independent prognostic factor in follicular lymphoma
Shimono, Joji; Miyoshi, Hiroaki; Kato, Takeharu; Sugio, Takeshi; Miyawaki, Kohta; Kamimura, Tomohiko; Miyagishima, Takuto; Eto, Tetsuya; Imaizumi, Yoshitaka; Kato, Koji; Nagafuji, Koji; Akashi, Koichi; Seto, Masao; Teshima, Takanori; Ohshima, Koichi
2018-01-01
Hepatitis C virus (HCV) is a single-stranded RNA virus that not only affects hepatocytes, by B cells as well. It is thought that HCV is involved in the onset of B-cell lymphoma. The clinicopathological characteristics of HCV-positive diffuse large B-cell lymphoma (DLBCL) and HCV-positive splenic marginal zone lymphoma (SMZL) are known, but there has been no report on HCV-positive follicular lymphoma (FL). In this study, the clinicopathological characteristics of HCV-positive FL were examined in 263 patients with FL who were classified into a HCV-positive group with HCV antibody and negative groups without one. The number of patients with HCV-positive FL and HCV-negative FL was 10 (3.8%) and 253 (96.2%), respectively. The patients with HCV-positive FL commonly had more than one region of lymphadenopathy, Ann Arbor stage III/IV, hemoglobin <120 g/l, elevated lactate dehydrogenase level, and high-risk categorization of Follicular Lymphoma International Prognostic Index (FLIPI) than in patients with HCV-negative FL. Overall survival and progression-free survival were poorer in patients with HCV-positive FL than in those with HCV-negative FL (p < 0.0001 and 0.006, respectively). Also, multivariate analysis revealed that positive HCV antibody was a poor prognostic factor of OS. In conclusion, HCV-positive FL has unique clinical features and may have a great impact on the overall survival of affected patients. PMID:29416725
Hepatitis C virus infection is an independent prognostic factor in follicular lymphoma.
Shimono, Joji; Miyoshi, Hiroaki; Kato, Takeharu; Sugio, Takeshi; Miyawaki, Kohta; Kamimura, Tomohiko; Miyagishima, Takuto; Eto, Tetsuya; Imaizumi, Yoshitaka; Kato, Koji; Nagafuji, Koji; Akashi, Koichi; Seto, Masao; Teshima, Takanori; Ohshima, Koichi
2018-01-05
Hepatitis C virus (HCV) is a single-stranded RNA virus that not only affects hepatocytes, by B cells as well. It is thought that HCV is involved in the onset of B-cell lymphoma. The clinicopathological characteristics of HCV-positive diffuse large B-cell lymphoma (DLBCL) and HCV-positive splenic marginal zone lymphoma (SMZL) are known, but there has been no report on HCV-positive follicular lymphoma (FL). In this study, the clinicopathological characteristics of HCV-positive FL were examined in 263 patients with FL who were classified into a HCV-positive group with HCV antibody and negative groups without one. The number of patients with HCV-positive FL and HCV-negative FL was 10 (3.8%) and 253 (96.2%), respectively. The patients with HCV-positive FL commonly had more than one region of lymphadenopathy, Ann Arbor stage III/IV, hemoglobin <120 g/l, elevated lactate dehydrogenase level, and high-risk categorization of Follicular Lymphoma International Prognostic Index (FLIPI) than in patients with HCV-negative FL. Overall survival and progression-free survival were poorer in patients with HCV-positive FL than in those with HCV-negative FL ( p < 0.0001 and 0.006, respectively). Also, multivariate analysis revealed that positive HCV antibody was a poor prognostic factor of OS. In conclusion, HCV-positive FL has unique clinical features and may have a great impact on the overall survival of affected patients.
Subramanian, Manikandan; Ozcan, Lale; Ghorpade, Devram Sampat; Ferrante, Anthony W; Tabas, Ira
2015-01-01
Obesity-induced inflammation in visceral adipose tissue (VAT) is a major contributor to insulin resistance and type 2 diabetes. Whereas innate immune cells, notably macrophages, contribute to visceral adipose tissue (VAT) inflammation and insulin resistance, the role of adaptive immunity is less well defined. To address this critical gap, we used a model in which endogenous activation of T cells was suppressed in obese mice by blocking MyD88-mediated maturation of CD11c+ antigen-presenting cells. VAT CD11c+ cells from Cd11cCre+Myd88fl/fl vs. control Myd88fl/fl mice were defective in activating T cells in vitro, and VAT T and B cell activation was markedly reduced in Cd11cCre+Myd88fl/fl obese mice. However, neither macrophage-mediated VAT inflammation nor systemic inflammation were altered in Cd11cCre+Myd88fl/fl mice, thereby enabling a focused analysis on adaptive immunity. Unexpectedly, fasting blood glucose, plasma insulin, and the glucose response to glucose and insulin were completely unaltered in Cd11cCre+Myd88fl/fl vs. control obese mice. Thus, CD11c+ cells activate VAT T and B cells in obese mice, but suppression of this process does not have a discernible effect on macrophage-mediated VAT inflammation or systemic glucose homeostasis.
Akçakaya, Mehmet Osman; Göker, Burcu; Kasımcan, Mustafa Ömür; Hamamcıoğlu, Mustafa Kemal; Kırış, Talat
2017-11-01
To evaluate the feasibility of sodium fluorescein (Na-Fl)-guided surgery involving the use of the PENTERO 900 surgical microscope equipped with the YELLOW-560 nm filter and low-dose Na-FL (200 mg/2-4 mg/kg) in meningioma surgery. The study included 30 patients with newly diagnosed or recurrent meningiomas who underwent Na-Fl-guided surgery between April 2015 and December 2016. Clinical features, surgical observations, extent of resection, and tumor histopathology were retrospectively analyzed. The Na-Fl enhancement pattern was assessed as "no enhancement," "diffuse homogenous enhancement," or "low heterogeneous enhancement." There were 30 meningiomas among the 30 patients. In 25 patients, Na-Fl was used for tumor demarcation, whereas in 5 patients, it was used for videoangiography. In this series, 88% of tumors showed diffuse homogeneous Na-Fl enhancement during the operation. The resection rate of the meningiomas was 87%. In 5 patients, in whom Na-Fl was used for videoangiography, the approach was useful to evaluate Na-Fl-stained vessels for patency and to understand their relationship with the tumor. No adverse events were encountered with regard to Na-Fl use. Na-Fl guidance with the use of the YELLOW-560 filter is safe and effective during meningioma surgery. Copyright © 2017 Elsevier Inc. All rights reserved.
Penn, Jill K. M.; Graham, Patricia; Deshpande, Girish; Calhoun, Gretchen; Chaouki, Ahmad Sami; Salz, Helen K.; Schedl, Paul
2008-01-01
fl(2)d, the Drosophila homolog of Wilms'-tumor-1-associated protein (WTAP), regulates the alternative splicing of Sex-lethal (Sxl), transformer (tra), and Ultrabithorax (Ubx). Although WTAP has been found in functional human spliceosomes, exactly how it contributes to the splicing process remains unknown. Here we attempt to identify factors that interact genetically and physically with fl(2)d. We begin by analyzing the Sxl-Fl(2)d protein–protein interaction in detail and present evidence suggesting that the female-specific fl(2)d1 allele is antimorphic with respect to the process of sex determination. Next we show that fl(2)d interacts genetically with early acting general splicing regulators and that Fl(2)d is present in immunoprecipitable complexes with Snf, U2AF50, U2AF38, and U1-70K. By contrast, we could not detect Fl(2)d complexes containing the U5 snRNP protein U5-40K or with a protein that associates with the activated B spliceosomal complex SKIP. Significantly, the genetic and molecular interactions observed for Sxl are quite similar to those detected for fl(2)d. Taken together, our findings suggest that Sxl and fl(2)d function to alter splice-site selection at an early step in spliceosome assembly. PMID:18245840
Deciphering the groove binding modes of tau-fluvalinate and flumethrin with calf thymus DNA
NASA Astrophysics Data System (ADS)
Tao, Mo; Zhang, Guowen; Pan, Junhui; Xiong, Chunhong
2016-02-01
Tau-fluvalinate (TFL) and flumethrin (FL), widely used in agriculture and a class of synthetic pyrethroid pesticides with a similar structure, may cause a potential security risk. Herein, the modes of binding in vitro of TFL and FL with calf thymus DNA (ctDNA) were characterized by fluorescence, UV-vis absorption, circular dichroism (CD) and Fourier transform infrared (FT-IR) spectroscopy with the aid of viscosity measurements, melting analyses and molecular docking studies. The fluorescence titration indicated that both TFL and FL bound to ctDNA forming complexes through hydrogen bonding and van der Waals forces. The binding constants of TFL and FL with ctDNA were in the range of 104 L mol- 1, and FL exhibited a higher binding propensity than TFL. The iodide quenching effect, single/double-stranded DNA effects, and ctDNA melting and viscosity measurements demonstrated that the binding of both TFL and FL to ctDNA was groove mode. The FT-IR analyses suggested the A-T region of the minor groove of ctDNA as the preferential binding for TFL and FL, which was confirmed by the displacement assays with Hoechst 33258 probe, and the molecular docking visualized the specific binding. The changes in CD spectra indicated that both FL and TFL induced the perturbation on the base stacking and helicity of B-DNA, but the disturbance caused by FL was more obvious. Gel electrophoresis analyses indicated that both TFL and FL did not cause significant DNA cleavage. This study provides novel insights into the binding properties of TFL/FL with ctDNA and its toxic mechanisms.
NASA Technical Reports Server (NTRS)
Niiler, Peran P.
2004-01-01
The scientific objective of this research program was to utilize drifter, Jason-1 altimeter data and a variety of wind data for the determination of time mean and time variable wind driven surface currents of the global ocean. To accomplish this task has required the interpolation of 6-hourly winds on drifter tracks and the computation of the wind coherent motions of the drifters. These calculations showed that the Ekman current model proposed by Ralph and Niiler for the tropical Pacific was valid for all the oceans south of 40N latitude. Improvements to RN99 model were computed and poster presentations of the results were given in several ocean science venues, including the November 2004 GODAY meeting in St. Petersburg, FL.
U.S. Dept. of Defense Web Site Special: 2007 ESGR Awards, Sept. 12, 2007
- Defense Secretary Robert M. Gates praised a select group of civilian employers today for their exemplary recognized with Secretary of Defense Employer Freedom Awards. Story Dollar Thrifty Automotive Group Automotive Group, has gone the extra mile to make him feel good about his military service. Story Augustine
ERIC Educational Resources Information Center
Augustine, Adam A.; Hemenover, Scott H.
2013-01-01
In their examination of the effectiveness of affect regulation strategies, Webb, Miles, and Sheeran (2012) offered the results of a broad meta-analysis of studies on regulatory interventions. Their analysis provides an alternative to our earlier, more focused meta-analysis of the affect regulation literature (Augustine & Hemenover, 2009).…
Learning to Read the Bible with Desire: Teaching the Eros of Exegesis in the Theological Classroom
ERIC Educational Resources Information Center
Vaage, Leif E.
2007-01-01
The article begins with two brief theoretical descriptions of a pedagogy of desire vis-a-vis the Christian Bible. The first of these is a poem; the second summarizes the conversation constituted by four quite different books: the "Confessions" by Augustine of Hippo, "Freud & Philosophy" by Paul Ricoeur, "Pedagogy of…
ERIC Educational Resources Information Center
Herdt, Jennifer A.
2015-01-01
Augustine's training in pagan rhetoric, his classical education, and the productive tensions he experienced between pagan and Christian exemplars played a formative role in his spiritual journey. An examination of the generative aspects of these encounters with otherness yields insights for our own understanding, not just of the importance to…
Human Space Flight Plans Committee
2009-08-11
Members of the Human Space Flight Review Committee from left, Jeffrey Greason, Dr. Christopher Chyba, Dr. Leroy Chiao, Dr. Sally Ride, Norman Augustine (chair), Philip McAllister, Dr. Edward Crawley, Dr. Wanda Austin, and Bhodan Bejmuk review their notes prior to the start of a public meeting, Wednesday, Aug. 12, 2009, in Washington. Photo Credit: (NASA/Paul E. Alers)
Human Space Flight Plans Committee
2009-08-11
Members of the Human Space Flight Review Committee from left, Jeffrey Greason, Dr. Christopher Chyba, Dr. Leroy Chiao, Dr. Sally Ride, Norman Augustine (chair), Philip McAllister, Dr. Edward Crawley, Dr. Wanda Austin (not seen), and Bhodan Bejmuk review their notes prior to the start of a public meeting, Wednesday, Aug. 12, 2009, in Washington. Photo Credit: (NASA/Paul E. Alers)
For the Future of Chinese Universities: Three Conversations from the Past
ERIC Educational Resources Information Center
Pickus, David
2016-01-01
This article argues that ideas from the ancient past supply insight about the future of Chinese universities. I make this case by outlining three claims about the nature and purpose of education in Homer, Plato, and Augustine. I propose that conversations based on these ideas illuminate central underlying problems facing Chinese higher education…
An Augustinian Culture of Learning for Interdisciplinary Honors Programs
ERIC Educational Resources Information Center
Ste. Antoine, Tom
2010-01-01
Any attempt to discern the purpose of honors education and to integrate it with the unique ethos of a Christian institution can prove to be difficult. Yet, describing and articulating a sense of purpose is essential for an honors program to justify itself. This essay contends that a philosophy of education based on Augustine's…
Transformation of follicular lymphoma to plasmablastic lymphoma with c-myc gene rearrangement.
Ouansafi, Ihsane; He, Bing; Fraser, Cory; Nie, Kui; Mathew, Susan; Bhanji, Rumina; Hoda, Rana; Arabadjief, Melissa; Knowles, Daniel; Cerutti, Andrea; Orazi, Attilio; Tam, Wayne
2010-12-01
Follicular lymphoma (FL) is an indolent lymphoma that transforms to high-grade lymphoma, mostly diffuse large B-cell lymphoma, in about a third of patients. We present the first report of a case of FL that transformed to plasmablastic lymphoma (PBL). Clonal transformation of the FL to PBL was evidenced by identical IGH/BCL2 gene rearrangements and VDJ gene usage in rearranged IGH genes. IGH/ BCL2 translocation was retained in the PBL, which also acquired c-myc gene rearrangement. Genealogic analysis based on somatic hypermutation of the rearranged IGH genes of both FL and PBL suggests that transformation of the FL to PBL occurred most likely by divergent evolution from a common progenitor cell rather than direct evolution from the FL clone. Our study of this unusual case expands the histologic spectrum of FL transformation and increases our understanding of the pathogenetic mechanisms of transformation of indolent lymphomas to aggressive lymphomas.
75 FR 82228 - IFR Altitudes; Miscellaneous Amendments
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-30
... Is Amended To Read in Part Shirt, OH FIX *Gloom, OH FIX 3000 *4000--MRA *Gloom, OH FIX Appleton, OH VORTAC..... 3000 *4000--MRA Appleton, OH VORTAC Mansfield, OH VORTAC.... 3000 Mansfield, OH VORTAC Dryer... in Part Lee County, FL VORTAC Jocks, FL FIX 2600 Jocks, FL FIX *Crowd, FL FIX **2300 *5000--MRA...
Draft Genome Sequence of Mycobacterium chimaera Type Strain Fl-0169
We report the draft genome sequence of the type strain Mycobacterium chimaera Fl-0169T, a member of the Mycobacterium avium complex (MAC). M. chimaera Fl-0169T was isolated from a patient in Italy and is highly similar to strains of M. chimaera isolated in Ireland, though Fl-016...
77 FR 38384 - Qualification of Drivers; Exemption Applications; Vision
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-27
... S. Johannsen (IA) Charles E. Johnston (MO) Harry L. Jones (OH) Mearl C. Kennedy (OH) Aaron C...) Bobby G. Minton (NC) Charles J. Morman (FL) Larry A. Nienhuis (MI) Corey L. Paraf (IL) Ronald M. Price (MD) John P. Raftis (FL) Scott D. Russell (WI) Alton M. Rutherford (FL) Charles L. Schnell (FL) Andrew...
33 CFR 80.760 - Horeshoe Point, FL to Rock Island, FL.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Horeshoe Point, FL to Rock Island... Rock Island, FL. (a) Except inside lines specifically described provided in this section, the 72 COLREGS shall apply on the bays, bayous, creeks, marinas, and rivers from Horseshoe Point to the Rock...
33 CFR 80.760 - Horeshoe Point, FL to Rock Island, FL.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Horeshoe Point, FL to Rock Island... Rock Island, FL. (a) Except inside lines specifically described provided in this section, the 72 COLREGS shall apply on the bays, bayous, creeks, marinas, and rivers from Horseshoe Point to the Rock...
33 CFR 80.760 - Horeshoe Point, FL to Rock Island, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Horeshoe Point, FL to Rock Island... Rock Island, FL. (a) Except inside lines specifically described provided in this section, the 72 COLREGS shall apply on the bays, bayous, creeks, marinas, and rivers from Horseshoe Point to the Rock...
33 CFR 80.760 - Horeshoe Point, FL to Rock Island, FL.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Horeshoe Point, FL to Rock Island... Rock Island, FL. (a) Except inside lines specifically described provided in this section, the 72 COLREGS shall apply on the bays, bayous, creeks, marinas, and rivers from Horseshoe Point to the Rock...
33 CFR 80.760 - Horeshoe Point, FL to Rock Island, FL.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Horeshoe Point, FL to Rock Island... Rock Island, FL. (a) Except inside lines specifically described provided in this section, the 72 COLREGS shall apply on the bays, bayous, creeks, marinas, and rivers from Horseshoe Point to the Rock...
77 FR 21662 - Amendment of Class D Airspace; Cocoa Beach, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-11
...-0099; Airspace Docket No. 12-ASO-11] Amendment of Class D Airspace; Cocoa Beach, FL AGENCY: Federal... Class D airspace at Cape Canaveral Skid Strip, Cocoa Beach, FL, by correcting the geographic coordinates... of Cape Canaveral Skid Strip, Cocoa Beach, FL. Also, the geographic coordinates for the airport need...
78 FR 38554 - Amendment of Class E Airspace; Live Oak, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-27
... Live Oak, FL area, as new Standard Instrument Approach Procedures (SIAPs) have been developed at... from 700 feet above the surface within a 7-mile radius at Suwannee County Airport, Live Oak, FL. New...-0001; Airspace Docket No. 12-ASO-45] Amendment of Class E Airspace; Live Oak, FL AGENCY: Federal...
Protection of Flos Lonicerae against acetaminophen-induced liver injury and its mechanism.
Jiang, Ping; Sheng, Yu-chen; Chen, Yu-hao; Ji, Li-li; Wang, Zheng-tao
2014-11-01
This study aims to observe the protective action of Flos Lonicerae (FL) aqueous extract against acetaminophen (AP)-induced liver injury and its mechanism. Results show that FL decreases AP-increased serum alanine/aspartate transaminases (ALT/AST) activity, as well as total bilirubin (TB) amount, in mice. Histological evaluation of the liver further confirms the protection of FL against AP-induced hepatotoxicity. TdT-mediated biotin-dUTP nick-end labeling (TUNEL) assay shows that FL reduces AP-increased apoptotic cells. Furthermore, AP-decreased liver glutamate-cysteine ligase (GCL) enzymatic activity and glutathione (GSH) amount are both reversed by FL because of the increased expression of the catalytic subunit of GCL (GCLC) protein. The amount of chlorogenic acid (CGA), caffeic acid, and luteolin, the main active compounds in FL, is detected by high-performance liquid chromatography (HPLC). In addition, cell viability assay demonstrates that polyphenols in FL, such as CGA, caffeic acid, as well as isochlorogenic acids A, B, and C, can reverse AP-induced cytotoxicity. In conclusion, FL can prevent AP-induced liver injury by inhibiting apoptosis. The cellular antioxidant enzyme GCL is also involved in such protection. Polyphenols may be the main active hepato-protective ingredients in FL. Copyright © 2014 Elsevier B.V. All rights reserved.
Vazquez, Enrique; Barranco, Alejandro; Ramirez, Maria; Gruart, Agnes; Delgado-Garcia, Jose M.; Jimenez, Maria L.; Buck, Rachael; Rueda, Ricardo
2016-01-01
2´-fucosyllactose (2´-FL) is an abundant human milk oligosaccharide (HMO) in human milk with diverse biological effects. We recently reported ingested 2´-FL stimulates central nervous system (CNS) function, such as hippocampal long term potentiation (LTP) and learning and memory in rats. Conceivably the effect of 2´-FL on CNS function may be via the gut-brain axis (GBA), specifically the vagus nerve, and L-fucose (Fuc) may play a role. This study had two aims: (1) determine if the effect of ingested 2´-FL on the modulation of CNS function is dependent on the integrity of the molecule; and (2) confirm if oral 2´-FL modified hippocampal LTP and associative learning related skills in rats submitted to bilateral subdiaphragmatic vagotomy. Results showed that 2´-FL but not Fuc enhanced LTP, and vagotomy inhibited the effects of oral 2´-FL on LTP and associative learning related paradigms. Taken together, the data show that dietary 2´-FL but not its Fuc moiety affects cognitive domains and improves learning and memory in rats. This effect is dependent on vagus nerve integrity, suggesting GBA plays a role in 2´-FL-mediated cognitive benefits. PMID:27851789
Amin, Rada; Mourcin, Frédéric; Uhel, Fabrice; Pangault, Céline; Ruminy, Philippe; Dupré, Loic; Guirriec, Marion; Marchand, Tony; Fest, Thierry; Lamy, Thierry
2015-01-01
Follicular lymphoma (FL) results from the accumulation of malignant germinal center (GC) B cells leading to the development of an indolent and largely incurable disease. FL cells remain highly dependent on B-cell receptor (BCR) signaling and on a specific cell microenvironment, including T cells, macrophages, and stromal cells. Importantly, FL BCR is characterized by a selective pressure to retain surface immunoglobulin M (IgM) BCR despite an active class-switch recombination process, and by the introduction, in BCR variable regions, of N-glycosylation acceptor sites harboring unusual high-mannose oligosaccharides. However, the relevance of these 2 FL BCR features for lymphomagenesis remains unclear. In this study, we demonstrated that IgM+ FL B cells activated a stronger BCR signaling network than IgG+ FL B cells and normal GC B cells. BCR expression level and phosphatase activity could both contribute to such heterogeneity. Moreover, we underlined that a subset of IgM+ FL samples, displaying highly mannosylated BCR, efficiently bound dendritic cell–specific intercellular adhesion molecule-3–grabbing nonintegrin (DC-SIGN), which could in turn trigger delayed but long-lasting BCR aggregation and activation. Interestingly, DC-SIGN was found within the FL cell niche in situ. Finally, M2 macrophages induced a DC-SIGN–dependent adhesion of highly mannosylated IgM+ FL B cells and triggered BCR-associated kinase activation. Interestingly, pharmacologic BCR inhibitors abolished such crosstalk between macrophages and FL B cells. Altogether, our data support an important role for DC-SIGN–expressing infiltrating cells in the biology of FL and suggest that they could represent interesting therapeutic targets. PMID:26272216
Kappus, Mojdeh S; Murphy, Andrew J; Abramowicz, Sandra; Ntonga, Vusisizwe; Welch, Carrie L; Tall, Alan R; Westerterp, Marit
2014-02-01
Liver X receptor (LXR) activators decrease atherosclerosis in mice. LXR activators (1) directly upregulate genes involved in reverse cholesterol transport and (2) exert anti-inflammatory effects mediated by transrepression of nuclear factor-κB target genes. We investigated whether myeloid cell deficiency of ATP-binding cassette transporters A1 and G1 (ABCA1/G1), principal targets of LXR that promote macrophage cholesterol efflux and initiate reverse cholesterol transport, would abolish the beneficial effects of LXR activation on atherosclerosis. LXR activator T0901317 substantially reduced inflammatory gene expression in macrophages lacking ABCA1/G1. Ldlr(-/-) mice were transplanted with Abca1(-/-)Abcg1(-/-) or wild-type bone marrow (BM) and fed a Western-type diet for 6 weeks with or without T0901317 supplementation. Abca1/g1 BM deficiency increased atherosclerotic lesion complexity and inflammatory cell infiltration into the adventitia and myocardium. T0901317 markedly decreased lesion area, complexity, and inflammatory cell infiltration in the Abca1(-/-)Abcg1(-/-) BM-transplanted mice. To investigate whether this was because of macrophage Abca1/g1 deficiency, Ldlr(-/-) mice were transplanted with LysmCreAbca1(fl/fl)Abcg1(fl/fl) or Abca1(fl/fl)Abcg1(fl/fl) BM and fed Western-type diet with or without the more specific LXR agonist GW3965 for 12 weeks. GW3965 decreased lesion size in both groups, and the decrease was more prominent in the LysmCreAbca1(fl/fl)Abcg1(fl/fl) group. The results suggest that anti-inflammatory effects of LXR activators are of key importance to their antiatherosclerotic effects in vivo independent of cholesterol efflux pathways mediated by macrophage ABCA1/G1. This has implications for the development of LXR activators that lack adverse effects on lipogenic genes while maintaining the ability to transrepress inflammatory genes.
Chen, Yingjia; Hu, Fanlei; Dong, Xuejiao; Zhao, Meng; Wang, Jing; Sun, Xiaolin; Kim, Tae Jin; Li, Zhanguo; Liu, Wanli
2017-11-01
Unlike conventional B cells, regulatory B cells exhibit immunosuppressive functions to downregulate inflammation via IL-10 production. However, the molecular mechanism regulating the production of IL-10 is not fully understood. In this study, we report the finding that activation-induced cytidine deaminase (AID) is highly upregulated in the IL-10-competent B cell (B10) cell from Innp5d fl/fl Aicda Cre/+ mice, whereas the 5' inositol phosphatase SHIP-1 is downregulated. Notably, SHIP-1 deficiency in AID + B cells leads to a reduction in cell count and impaired IL-10 production by B10 cells. Furthermore, the Innp5d fl/fl Aicda Cre/+ mouse model shows B cell-dependent autoimmune lupus-like phenotypes, such as elevated IgG serum Abs, formation of spontaneous germinal centers, production of anti-dsDNA and anti-nuclear Abs, and the obvious deposition of IgG immune complexes in the kidney with age. We observe that these lupus-like phenotypes can be reversed by the adoptive transfer of B10 cells from control Innp5d fl/fl mice, but not from the Innp5d fl/fl Aicda Cre/+ mice. This finding highlights the importance of defective B10 cells in Innp5d fl/fl Aicda Cre/+ mice. Whereas p-Akt is significantly upregulated, MAPK and AP-1 activation is impaired in B10 cells from Innp5d fl/fl Aicda Cre/+ mice, resulting in the reduced production of IL-10. These results show that SHIP-1 is required for the maintenance of B10 cells and production of IL-10, and collectively suggests that SHIP-1 could be a new potential therapeutic target for the treatment of autoimmune diseases. Copyright © 2017 by The American Association of Immunologists, Inc.
Reduced Cx43 expression triggers increased fibrosis due to enhanced fibroblast activity.
Jansen, John A; van Veen, Toon A B; de Jong, Sanne; van der Nagel, Roel; van Stuijvenberg, Leonie; Driessen, Helen; Labzowski, Ronald; Oefner, Carolin M; Bosch, Astrid A; Nguyen, Tri Q; Goldschmeding, Roel; Vos, Marc A; de Bakker, Jacques M T; van Rijen, Harold V M
2012-04-01
Arrhythmogenic ventricular remodeling is hallmarked by both reduced gap junction expression and increased collagen deposition. We hypothesized that reduced connexin43 (Cx43) expression is responsible for enhanced fibrosis in the remodeled heart, resulting in an arrhythmogenic substrate. Therefore, we investigated the effect of normal or reduced Cx43 expression on the formation of fibrosis in a physiological (aging) and pathophysiological (transverse aortic constriction [TAC]) mouse model. The Cx43(fl/fl) and Cx43(CreER(T)/fl) mice were aged 18 to 21 months or, at the age of 3 months, either TAC or sham operated and euthanized after 16 weeks. Epicardial activation mapping of the right and left ventricles was performed on Langendorff perfused hearts. Sustained ventricular arrhythmias were induced in 0 of 11 aged Cx43(fl/fl) and 10 of 15 Cx43(Cre-ER(T)/fl) mice (P<0.01). Cx43 expression was reduced by half in aged Cx43(CreER(T)/fl) compared with aged Cx43(fl/fl) mice, whereas collagen deposition was significantly increased from 1.1±0.2% to 7.4±1.3%. Aged Cx43(CreER(T)/fl) mice with arrhythmias had significantly higher levels of fibrosis and conduction heterogeneity than aged Cx43(CreER(T)/fl) mice without arrhythmias. The TAC operation significantly increased fibrosis in control compared with sham (4.0±1.2% versus 0.4±0.06%), but this increase was significantly higher in Cx43(CreER(T)/fl) mice (10.8±1.4%). Discoidin domain receptor 2 expression was unchanged, but procollagen peptide I and III expression and collagen type 1α2 mRNA levels were higher in TAC-operated Cx43HZ mice. Reduced cellular coupling results in more excessive collagen deposition during aging or pressure overload in mice due to enhanced fibroblast activity, leading to increased conduction in homogeneity and proarrhythmia.
Kosmidis, Perikles; Mankel, Barbara; Fend, Falko; Adam, Patrick
2018-05-02
The translocation t(14;18)(q32;q21) is the genetic hallmark of follicular lymphoma (FL) and can be observed in 85-90% of cases. Whether the translocation is restricted to cells with germinal center B-cell phenotype or can be observed in other cell types of the microenvironment remains debated. Of interest, cases of associated histiocytic and dendritic cell sarcomas arising in the background of FL have been shown to be clonally related and carry the t(14;18), suggesting a "transdifferentiation" of the malignant FL clone into a neoplasm of a different hematopoietic lineage. We analyzed the presence of the t(14;18)(q32;q21) as a surrogate marker of the malignant clone in cells of the FL microenvironment using combined fluorescence immunophenotyping and interphase cytogenetics targeting the BCL2 gene locus. In addition to non-lymphoid cells in FL, we analysed FL with preserved IgD+ mantle zones and cases of in situ follicular neoplasia (ISFN) to investigate whether cells of non-germinal center B-cell phenotype are part of the malignant clone. Six (40%) of 15 manifest FL cases with preserved IgD+ mantle zones did not harbour the t(14;18)(q32;q21) translocation. In all t(14;18) + FL cases, follicular dendritic cells and endothelial cells lacked the t(14;18) translocation. 2/9 FL revealed t(14;18)- IgD+ mantle zone B-cells. In the seven ISFN cases, the t(14;18) translocation was strictly confined to germinal center cells. The t(14;18) translocation in follicular lymphoma is limited to B-cells. The origin of IgD+ mantle cells is heterogeneous, in the majority of cases belonging to the neoplastic clone, whereas a minority of cases of manifest FL show nonneoplastic mantle zones, similar to ISFN.
Yang, Shuman; Feskanich, Diane; Willett, Walter C; Eliassen, A Heather; Wu, Tianying
2014-12-01
Human studies suggest that oxidative stress is a risk factor for osteoporosis, but its relationship with fracture risk is poorly understood. The purpose of the present study was to investigate the association between biomarkers of oxidative stress and hip fracture in postmenopausal women. We conducted a prospective study in the Nurses' Health Study among 996 women aged 60 years or older at baseline blood collection in 1989-1990. Plasma fluorescent oxidation products (FlOPs) were measured at three excitation/emission wavelengths (360/420 nm named as FlOP_360; 320/420 nm named as FlOP_320; and 400/475 nm named as FlOP_400). FlOPs are generated from many different pathways (lipid, protein, and DNA) and reflect a global oxidation burden. FlOP assay is 10-100 times more sensitive than measurement of malondialdehyde. We used Cox proportional hazards regression model to investigate the association between baseline plasma FlOPs and the risk of hip fracture, adjusting for multiple hip fracture risk factors such as age, history of osteoporosis, history of hypertension, prior fracture, and smoking status. Forty-four hip fractures (4.4%) were identified during the follow-up (maximum = 23 years). In the multivariable model, the hazard ratios (HRs) of hip fracture in the second and third tertiles of FlOP_320 were 2.11 (95% confidence interval [CI] = 0.88-5.10) and 2.67 (95% CI = 1.14-6.27), respectively, in comparison with the lowest tertile, and the risk increased linearly with increasing FlOP_320 (p for trend = 0.021). Neither FlOP_360 nor FlOP_400 was significantly associated with risk of hip fracture (tertile 3 versus tertile 1: HR = 0.70, 95% CI = 0.32-1.54, p for trend = 0.386 for FlOP_360; and HR = 0.88, 95% CI = 0.40-1.96, p for trend = 0.900 for FlOP_400). In this prospective study, higher plasma FlOP_320 was an independent risk factor for hip fracture. Our results need further confirmation. © 2014 American Society for Bone and Mineral Research.
Cross-Cultural Perspective of FL Teaching and Learning in the Polish Context
ERIC Educational Resources Information Center
Sobkowiak, Pawel
2012-01-01
This study examines whether learners' capacity to use a foreign language (FL) successfully in the global world is developed in the FL classroom in Polish high schools. The article reports results of the quantitative research which aimed at assessing whether and to what extent homogeneous FL classes in Poland are conducive to developing learners'…
75 FR 20608 - Notice of Re-Designation of the Service Delivery Area for the Cowlitz Indian Tribe
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-20
..., Louisiana Grand Parish, LA,\\22\\ LaSalle Parish, LA, Rapides Parish, LA. Jicarilla Apache Nation, New Mexico... Mexico. NM. Miccosukee Tribe of Indians of Florida. Broward, FL, Collier, FL, Miami- Dade, FL, Hendry, FL.... Narragansett Indian Tribe of Rhode Washington, RI.\\32\\ Island. Navajo Nation, Arizona, New Mexico and Apache...
77 FR 28243 - Amendment of Class D Airspace; Cocoa Beach, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-14
...-0099; Airspace Docket No. 12-ASO-11] Amendment of Class D Airspace; Cocoa Beach, FL AGENCY: Federal... Federal Register on April 11, 2012 that amends Class D airspace at Cocoa Beach, FL. DATES: Effective 0901...), amends Class D airspace at Cape Canaveral Skid Strip, Cocoa Beach, FL. A typographical error was made in...
78 FR 37105 - Modification of VOR Federal Airway V-537, GA
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-20
..., GA, VOR/DME navigation aid which currently forms a point along the route. DATES: Effective date 0901... and the Macon, GA, VORTAC. The modified V-537 extends between Palm Beach, FL, and Greenville, FL. VOR... * * * * * V-537 [Amended] From Palm Beach, FL; INT Palm Beach 356[deg] and Treasure, FL, 143[deg] radials...
33 CFR 80.748 - Cape Romano, FL to Sanibel Island, FL.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Cape Romano, FL to Sanibel Island... Sanibel Island, FL. (a) A line drawn across Big Marco Pass parallel to the general trend of the seaward, highwater shoreline. (b) A line drawn from the northwesternmost extremity of Coconut Island 000°T across...
33 CFR 80.748 - Cape Romano, FL to Sanibel Island, FL.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Cape Romano, FL to Sanibel Island... Sanibel Island, FL. (a) A line drawn across Big Marco Pass parallel to the general trend of the seaward, highwater shoreline. (b) A line drawn from the northwesternmost extremity of Coconut Island 000°T across...
33 CFR 80.748 - Cape Romano, FL to Sanibel Island, FL.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Cape Romano, FL to Sanibel Island... Sanibel Island, FL. (a) A line drawn across Big Marco Pass parallel to the general trend of the seaward, highwater shoreline. (b) A line drawn from the northwesternmost extremity of Coconut Island 000°T across...
33 CFR 80.748 - Cape Romano, FL to Sanibel Island, FL.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Cape Romano, FL to Sanibel Island... Sanibel Island, FL. (a) A line drawn across Big Marco Pass parallel to the general trend of the seaward, highwater shoreline. (b) A line drawn from the northwesternmost extremity of Coconut Island 000°T across...
33 CFR 80.748 - Cape Romano, FL to Sanibel Island, FL.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Cape Romano, FL to Sanibel Island... Sanibel Island, FL. (a) A line drawn across Big Marco Pass parallel to the general trend of the seaward, highwater shoreline. (b) A line drawn from the northwesternmost extremity of Coconut Island 000°T across...
ERIC Educational Resources Information Center
Abu-Rabia, Salim
2004-01-01
This study investigated the relationship between foreign language (FL) anxiety and achievement in that language. The role of the FL teacher as perceived by the learners was also tested. Participants were 67 seventh-grade students. They were administered an anxiety questionnaire, a Hebrew reading comprehension test, an English reading comprehension…
Phobic Anxiety and Plasma Levels of Global Oxidative Stress in Women.
Hagan, Kaitlin A; Wu, Tianying; Rimm, Eric B; Eliassen, A Heather; Okereke, Olivia I
2015-01-01
Psychological distress has been hypothesized to be associated with adverse biologic states such as higher oxidative stress and inflammation. Yet, little is known about associations between a common form of distress - phobic anxiety - and global oxidative stress. Thus, we related phobic anxiety to plasma fluorescent oxidation products (FlOPs), a global oxidative stress marker. We conducted a cross-sectional analysis among 1,325 women (aged 43-70 years) from the Nurses' Health Study. Phobic anxiety was measured using the Crown-Crisp Index (CCI). Adjusted least-squares mean log-transformed FlOPs were calculated across phobic categories. Logistic regression models were used to calculate odds ratios (OR) comparing the highest CCI category (≥6 points) vs. lower scores, across FlOPs quartiles. No association was found between phobic anxiety categories and mean FlOP levels in multivariable adjusted linear models. Similarly, in multivariable logistic regression models there were no associations between FlOPs quartiles and likelihood of being in the highest phobic category. Comparing women in the highest vs. lowest FlOPs quartiles: FlOP_360: OR=0.68 (95% CI: 0.40-1.15); FlOP_320: OR=0.99 (95% CI: 0.61-1.61); FlOP_400: OR=0.92 (95% CI: 0.52, 1.63). No cross-sectional association was found between phobic anxiety and a plasma measure of global oxidative stress in this sample of middle-aged and older women.
Arroyo, Mary T K; Dudley, Leah S; Jespersen, Gus; Pacheco, Diego A; Cavieres, Lohengrin A
2013-12-01
How high-alpine plants confront stochastic conditions for animal pollination is a critical question. We investigated the effect of temperature on potential flower longevity (FL) measured in pollinator-excluded flowers and actual FL measured in pollinated flowers in self-incompatible Oxalis compacta and evaluated if plastically prolonged potential FL can ameliorate slow pollination under cool conditions. Pollinator-excluded and hand-pollinated flowers were experimentally warmed with open-top chambers (OTCs) on a site at 3470 m above sea level (asl). Flower-specific temperatures, and pollinator-excluded and open-pollination flower life-spans were measured at six alpine sites between 3100 and 3470 m asl. Fruit set was analyzed in relation to inferred pollination time. Warming reduced potential FL. Variable thermal conditions across the alpine landscape predicted potential and actual FL; flower senescence was pollination-regulated. Actual FL and potential FL were coupled. Prolonged potential FL generally increased fruit set under cooler conditions. Plastic responses permit virgin flowers of O. compacta to remain open longer under cooler temperatures, thereby ameliorating slow pollination, and to close earlier when pollination tends to be faster under warmer conditions. Plastic potential FL provides adaptive advantages in the cold, thermally variable alpine habitat, and has important implications for reproductive success in alpine plants in a warming world. © 2013 The Authors. New Phytologist © 2013 New Phytologist Trust.
ERIC Educational Resources Information Center
Hu, Chieh-Fang; Schuele, C. Melanie
2015-01-01
Although language experience is a key factor in successful foreign language (FL) learning, many FL learners fail to achieve performance levels that were predicted on the basis of their FL experience. This retrospective study investigated early cognitive and linguistic correlates of learning English as a foreign language (FL) in a group of…
Bertho, Jean Marc; Demarquay, Christelle; Mouiseddine, Moubarak; Douenat, Noémie; Stefani, Johanna; Prat, Marie; Paquet, François
2008-08-01
To define the ability of human bone marrow (BM) stromal cells to produce fms-like tyrosine kinase 3 (Flt3)-ligand (FL), and the effect of irradiation, tumour necrosis factor-alpha (TNFalpha) or tumour growth factor beta (TGFbeta) on FL production. Primary BM stromal cell cultures were irradiated at 2-10 Gy or were stimulated with TNFalpha or TGFbeta1. The presence of FL was tested in culture supernatants and in cell lysate. The presence of a membrane-bound form of FL and the level of gene expression were also tested. Primary BM stromal cells spontaneously released FL. This production was increased by TNFalpha but not by TGFbeta1 or by irradiation. Chemical induction of osteoblastic differentiation from BM stromal cells also induced an increase in FL release. Our results suggest that the observed increase in FL concentration after in vivo irradiation is an indirect effect. The possible implication of BM stromal cells in these mechanisms is discussed.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-16
... Southern Railway Company in Chicago, Cook County, Ill.\\3\\ \\1\\ KMR is indirectly owned by noncarrier Koch Industries, Inc. (Koch). In addition to KMR, Koch also controls directly or indirectly three other Class III... Augustine Railroad, LLC), and Koch has sought Board authority to control a fourth Class III rail carrier...
Southern pine beetle infestation probability mapping using weights of evidence analysis
Jason B. Grogan; David L. Kulhavy; James C. Kroll
2010-01-01
Weights of Evidence (WofE) spatial analysis was used to predict probability of southern pine beetle (Dendroctonus frontalis) (SPB) infestation in Angelina, Nacogdoches, San Augustine and Shelby Co., TX. Thematic data derived from Landsat imagery (1974â2002 Landsat 1â7) were used. Data layers included: forest covertype, forest age, forest patch size...
Rep. Garrett, Scott [R-NJ-5
2013-04-10
Senate - 06/18/2014 Received in the Senate and Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:
DOE Office of Scientific and Technical Information (OSTI.GOV)
Toyama, Hirofumi; Arai, Fumio; Hosokawa, Kentaro
Highlights: Black-Right-Pointing-Pointer High N-cad expression was detected in E12.5 mouse FL LT-HSCs (EPCR{sup +} LSK cells). Black-Right-Pointing-Pointer Immunohistochemically, N-cad{sup +} HSCs co-localized with sinusoidal ECs (Lyve-1{sup +} cells) in E12.5 FL, but these gradually detached in E15.5 and E18.5 FL. Black-Right-Pointing-Pointer N-cad{sup +} LSK cells in E12.5 FL exhibited higher LTR activity versus N-cad{sup -} LSK cells, which decreased in E15.5 and E18.5. Black-Right-Pointing-Pointer N-cad expression may confer high LTR activity to HSCs by facilitating interactions with the perisinusoidal niche in FL. -- Abstract: Adult hematopoietic stem cells (HSCs) are maintained in a microenvironment known as the stem cell niche.more » The regulation of HSCs in fetal liver (FL) and their niche, however, remains to be elucidated. In this study, we investigated the role of N-cadherin (N-cad) in the maintenance of HSCs during FL hematopoiesis. By using anti-N-cad antibodies (Abs) produced by our laboratory, we detected high N-cad expression in embryonic day 12.5 (E12.5) mouse FL HSCs, but not in E15.5 and E18.5 FL. Immunofluorescence staining revealed that N-cad{sup +}c-Kit{sup +} and N-cad{sup +} endothelial protein C receptor (EPCR){sup +} HSCs co-localized with Lyve-1{sup +} sinusoidal endothelial cells (ECs) in E12.5 FL and that some of these cells also expressed N-cad. However, N-cad{sup +} HSCs were also observed to detach from the perisinusoidal niche at E15.5 and E18.5, concomitant with a down-regulation of N-cad and an up-regulation of E-cadherin (E-cad) in hepatic cells. Moreover, EPCR{sup +} long-term (LT)-HSCs were enriched in the N-cad{sup +}Lin{sup -}Sca-1{sup +}c-Kit{sup +} (LSK) fraction in E12.5 FL, but not in E15.5 or E18.5 FL. In a long-term reconstitution (LTR) activity assay, higher engraftment associated with N-cad{sup +} LSK cells versus N-cad{sup -} LSK cells in E12.5 FL when transplanted into lethally irradiated recipient mice. However, the higher engraftment of N-cad{sup +} LSK cells decreased subsequently in E15.5 and E18.5 FL. It is possible that N-cad expression conferred higher LTR activity to HSCs by facilitating interactions with the perisinusoidal niche, especially at E12.5. The down-regulation of N-cad during FL hematopoiesis may help us better understand the regulation and mobility of HSCs before migration into BM.« less
Draft Genome Sequence of Mycobacterium chimaera Type Strain Fl-0169.
Pfaller, Stacy; Tokarev, Vasily; Kessler, Collin; McLimans, Christopher; Gomez-Alvarez, Vicente; Wright, Justin; King, Dawn; Lamendella, Regina
2017-02-23
We report here the draft genome sequence of the type strain Mycobacterium chimaera Fl-0169, a member of the Mycobacterium avium complex (MAC). M. chimaera Fl-0169 T was isolated from a patient in Italy and is highly similar to strains of M. chimaera isolated in Ireland, although Fl-0169 T possesses unique virulence genes. Copyright © 2017 Pfaller et al.
Audí, Laura; Esteban, Cristina; Carrascosa, Antonio; Espadero, Rosa; Pérez-Arroyo, Annalisa; Arjona, Rosa; Clemente, María; Wollmann, Hartmut; Fryklund, Linda; Parodi, Luis A
2006-12-01
A polymorphism in the human GH receptor gene (d3/fl-GHR) resulting in genomic deletion of exon 3 has been associated with the degree of height increase in response to GH therapy. The objective of the study was to evaluate the frequencies of d3/fl-GHR polymorphism genotypes in control and short small-for-gestational-age (SGA) populations. An adult control population with heights normally distributed (ACPNH) between -2 and +2 sd score (SDS) and a short non-GH-deficient SGA child population were selected. Thirty Spanish hospitals participated in the selection of the short non-GH-deficient SGA children in the setting of a controlled, randomized trial, and one of these hospitals selected the ACPNH. CONTROLS AND PATIENTS: Two hundred eighty-nine adult subjects of both sexes constituted the ACPNH and 247 children and adolescents of both sexes the short SGA patients. Heights and weights were recorded in the ACPNH, and auxologic and biochemical data were recorded at each hospital for the SGA patients; d3/fl-GHR genotypes were determined and data analyzed in a single hospital. In short SGA patients, d3/fl-GHR genotype frequencies were significantly different from those in ACPNH, with a higher frequency of fl/fl genotype (P < 0.0001). In ACPNH, a trend toward diminished d3/d3 genotype frequency was observed in the shortest height group (height
Kappus, Mojdeh S.; Murphy, Andrew J.; Abramowicz, Sandra; Ntonga, Vusisizwe; Welch, Carrie L.; Tall, Alan R.; Westerterp, Marit
2014-01-01
Objective Liver X Receptor (LXR) activators decrease atherosclerosis in mice. LXR activators (1) directly up-regulate genes involved in reverse cholesterol transport (RCT) and (2) exert anti-inflammatory effects mediated by transrepression of NFκB target genes. We investigated whether myeloid cell deficiency of ATP-binding cassette transporters A1 and G1 (ABCA1/G1), principal targets of LXR that promote macrophage cholesterol efflux and initiate RCT, would abolish the beneficial effects of LXR activation on atherosclerosis. Approach and Results LXR activator T0901317 (T0) substantially reduced inflammatory gene expression in macrophages lacking ABCA1/G1. Ldlr−/− mice were transplanted with Abca1−/−Abcg1−/− or wild-type bone marrow (BM) and fed a Western-type diet (WTD) for 6 weeks with or without T0 supplementation. Abca1/g1 BM deficiency increased atherosclerotic lesion complexity and inflammatory cell infiltration into the adventitia and myocardium. T0 markedly decreased lesion area, complexity and inflammatory cell infiltration in the Abca1−/−Abcg1−/− BM transplanted mice. To investigate whether this was due to macrophage Abca1/g1 deficiency, Ldlr−/− mice were transplanted with LysmCreAbca1fl/flAbcg1fl/fl or Abca1fl/flAbcg1fl/fl BM and fed WTD with or without the more specific LXR agonist GW3965 for 12 weeks. GW3965 decreased lesion size in both groups and the decrease was more prominent in the LysmCreAbca1fl/flAbcg1fl/fl group. Conclusions The results suggest that anti-inflammatory effects of LXR activators are of key importance to their anti-atherosclerotic effects in vivo independent of cholesterol efflux pathways mediated by macrophage ABCA1/G1. This has implications for the development of LXR activators that lack adverse effects on lipogenic genes while maintaining the ability to trans-repress inflammatory genes. PMID:24311381
Anoctamin 1 contributes to inflammatory and nerve-injury induced hypersensitivity.
Lee, Byeongjun; Cho, Hawon; Jung, Jooyoung; Yang, Young Duk; Yang, Dong-Jin; Oh, Uhtaek
2014-01-23
Various pathological conditions such as inflammation or injury can evoke pain hypersensitivity. That represents the response to innocuous stimuli or exaggerated response to noxious stimuli. The molecular mechanism based on the pain hypersensitivity is associated with changes in many of ion channels in dorsal-root ganglion (DRG) neurons. Anoctamin 1 (ANO1/TMEM16A), a Ca2+ activated chloride channel is highly visible in small DRG neurons and responds to heat. Mice with an abolished function of ANO1 in DRG neurons demonstrated attenuated pain-like behaviors when exposed to noxious heat, suggesting a role in acute thermal nociception. In this study, we further examined the function of ANO1 in mediating inflammation- or injury-induced hyperalgesia or allodynia. Using Advillin/Ano1fl/fl (Adv/Ano1fl/fl) mice that have a functional ablation of Ano1 mainly in DRG neurons, we were able to determine its role in mediating thermal hyperalgesia and mechanical allodynia induced by inflammation or nerve injury. The thermal hyperalgesia and mechanical allodynia induced by carrageenan injection and spared-nerve injury were significantly reduced in Adv/Ano1fl/fl mice. In addition, flinching or licking behavior after bradykinin or formalin injection was also significantly reduced in Adv/Ano1fl/fl mice. Since pathological conditions augment nociceptive behaviors, we expected ANO1's contribution to the excitability of DRG neurons. Indeed, the application of inflammatory mediators reduced the threshold for action potential (rheobase) or time for induction of the first action potential in DRG neurons isolated from control (Ano1fl/fl) mice. These parameters for neuronal excitability induced by inflammatory mediators were not changed in Adv/Ano1fl/fl mice, suggesting an active contribution of ANO1 in augmenting the neuronal excitability. In addition to ANO1's role in mediating acute thermal pain as a heat sensor, ANO1 is also capable of augmenting the excitability of DRG neurons under inflammatory or neuropathic conditions and thereby aggravates inflammation- or tissue injury-induced pathological pain.
Segers, Patrick; Pineda, Victor; Cuellar, Hug; García-Dorado, David; Evangelista, Arturo
2017-01-01
Aortic wall stiffness, tear size and location and the presence of abdominal side branches arising from the false lumen (FL) are key properties potentially involved in FL enlargement in chronic aortic dissections (ADs). We hypothesize that temporal variations on FL flow patterns, as measured in a cross-section by phase-contrast magnetic resonance imaging (PC-MRI), could be used to infer integrated information on these features. In 33 patients with chronic descending AD, instantaneous flow profiles were quantified in the FL at diaphragm level by PC-MRI. We used a lumped-parameter model to assess the changes in flow profiles induced by wall stiffness, tear size/location, and the presence of abdominal side branches arising from the FL. Four characteristic FL flow patterns were identified in 31/33 patients (94%) based on the direction of flow in systole and diastole: BA = systolic biphasic flow and primarily diastolic antegrade flow (n = 6); BR = systolic biphasic flow and primarily diastolic retrograde flow (n = 14); MA = systolic monophasic flow and primarily diastolic antegrade flow (n = 9); MR = systolic monophasic flow and primarily diastolic retrograde flow (n = 2). In the computational model, the temporal variation of flow directions within the FL was highly dependent on the position of assessment along the aorta. FL flow patterns (especially at the level of the diaphragm) showed their characteristic patterns due to variations in the cumulative size and the spatial distribution of the communicating tears, and the incidence of visceral side branches originating from the FL. Changes in wall stiffness did not change the temporal variation of the flows whereas it importantly determined intraluminal pressures. FL flow patterns implicitly codify morphological information on key determinants of aortic expansion in ADs. This data might be taken into consideration in the imaging protocol to define the predictive value of FL flows. PMID:28125720
78 FR 9711 - Changes in Flood Hazard Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-11
..., Department, 2798 Key West, FL 33040. Overseas Highway, Marathon, FL 33050. Monroe (FEMA Docket No.: B.... Overseas Highway, Marathon, FL 33050. Sumter (FEMA Docket No.: B- Unincorporated areas The Honorable Garry...
Yiannikouris, Frederique; Wang, Yu; Shoemaker, Robin; Larian, Nika; Thompson, Joel; English, Victoria L; Charnigo, Richard; Su, Wen; Gong, Ming; Cassis, Lisa A
2015-10-01
We recently demonstrated that adipocyte deficiency of angiotensinogen (AGT) ablated high-fat diet-induced elevations in plasma angiotensin II (Ang II) concentrations and obesity-hypertension in male mice. Hepatocytes are the predominant source of systemic AGT. Therefore, in this study, we defined the contribution of hepatocyte-derived AGT to obesity-induced elevations in plasma AGT concentrations and hypertension. Male Agt(fl/fl) mice expressing albumin-driven Cre recombinase were bred to female Agt(fl/fl) mice to generate Agt(fl/fl) or hepatocyte AGT-deficient male mice (Agt(Alb)). Mice were fed a low-fat or high-fat diet for 16 weeks. Hepatocyte AGT deficiency had no significant effect on body weight. Plasma AGT concentrations were increased in obese Agt(fl/fl) mice. Hepatocyte AGT deficiency markedly reduced plasma AGT and Ang II concentrations in lean and obese mice. Moreover, hepatocyte AGT deficiency reduced the content and release of AGT from adipose explants. Systolic blood pressure was markedly decreased in lean (by 18 mm Hg) and obese Agt(Alb) mice (by 54 mm Hg) compared with Agt(fl/fl) controls. To define mechanisms, we quantified effects of Ang II on mRNA abundance of megalin, an AGT uptake transporter, in 3T3-L1 adipocytes. Ang II stimulated adipocyte megalin mRNA abundance and decreased media AGT concentrations. These results demonstrate that hepatocytes are the predominant source of systemic AGT in both lean and obese mice. Moreover, reductions in plasma angiotensin concentrations in obese hepatocyte AGT-deficient mice may have limited megalin-dependent uptake of AGT into adipocytes for the production of Ang II in the development of obesity-hypertension. © 2015 American Heart Association, Inc.
NASA Technical Reports Server (NTRS)
Liu, Chang; Deng, Na; Lee, Jeongwoo; Wiegelmann, Thomas; JIang, Chaowei; Dennis, Brian R.; Su, Yang; Donea, Alina; Wang, Haimin
2014-01-01
We carry out a comprehensive investigation comparing the three-dimensional magnetic field restructuring, flare energy release, and the helioseismic response of two homologous flares, the 2011 September 6 X2.1 (FL1) and September 7 X1.8 (FL2) flares in NOAA AR 11283. In our analysis, (1) a twisted flux rope (FR) collapses onto the surface at a speed of 1.5 km s(exp-1) after a partial eruption in FL1. The FR then gradually grows to reach a higher altitude and collapses again at 3 km s(exp-1) after a fuller eruption in FL2. Also, FL2 shows a larger decrease of the flux-weighted centroid separation of opposite magnetic polarities and a greater change of the horizontal field on the surface. These imply a more violent coronal implosion with corresponding more intense surface signatures in FL2. (2) The FR is inclined northward and together with the ambient fields, it undergoes a southward turning after both events. This agrees with the asymmetric decay of the penumbra observed in the peripheral regions. (3) The amounts of free magnetic energy and nonthermal electron energy released during FL1 are comparable to those of FL2 within the uncertainties of the measurements. (4) No sunquake was detected in FL1; in contrast, FL2 produced two seismic emission sources S1 and S2 both lying in the penumbral regions. Interestingly, S1 and S2 are connected by magnetic loops, and the stronger source S2 has a weaker vertical magnetic field. We discuss these results in relation to the implosion process in the low corona and the sunquake generation.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Liu, Chang; Deng, Na; Lee, Jeongwoo
We carry out a comprehensive investigation comparing the three-dimensional magnetic field restructuring, flare energy release, and the helioseismic response of two homologous flares, the 2011 September 6 X2.1 (FL1) and September 7 X1.8 (FL2) flares in NOAA AR 11283. In our analysis, (1) a twisted flux rope (FR) collapses onto the surface at a speed of 1.5 km s{sup –1} after a partial eruption in FL1. The FR then gradually grows to reach a higher altitude and collapses again at 3 km s{sup –1} after a fuller eruption in FL2. Also, FL2 shows a larger decrease of the flux-weighted centroidmore » separation of opposite magnetic polarities and a greater change of the horizontal field on the surface. These imply a more violent coronal implosion with corresponding more intense surface signatures in FL2. (2) The FR is inclined northward and together with the ambient fields, it undergoes a southward turning after both events. This agrees with the asymmetric decay of the penumbra observed in the peripheral regions. (3) The amounts of free magnetic energy and nonthermal electron energy released during FL1 are comparable to those of FL2 within the uncertainties of the measurements. (4) No sunquake was detected in FL1; in contrast, FL2 produced two seismic emission sources S1 and S2 both lying in the penumbral regions. Interestingly, S1 and S2 are connected by magnetic loops, and the stronger source S2 has a weaker vertical magnetic field. We discuss these results in relation to the implosion process in the low corona and the sunquake generation.« less
Bierie, Brian; Stover, Daniel G; Abel, Ty W; Chytil, Anna; Gorska, Agnieszka E; Aakre, Mary; Forrester, Elizabeth; Yang, Li; Wagner, Kay-Uwe; Moses, Harold L
2008-03-15
Transforming growth factor (TGF)-beta signaling has been associated with early tumor suppression and late tumor progression; however, many of the mechanisms that mediate these processes are not known. Using Cre/LoxP technology, with the whey acidic protein promoter driving transgenic expression of Cre recombinase (WAP-Cre), we have now ablated the type II TGF-beta receptor (T beta RII) expression specifically within mouse mammary alveolar progenitors. Transgenic expression of the polyoma virus middle T antigen, under control of the mouse mammary tumor virus enhancer/promoter, was used to produce mammary tumors in the absence or presence of Cre (T beta RII((fl/fl);PY) and T beta RII((fl/fl);PY;WC), respectively). The loss of TGF-beta signaling significantly decreased tumor latency and increased the rate of pulmonary metastasis. The loss of TGF-beta signaling was significantly correlated with increased tumor size and enhanced carcinoma cell survival. In addition, we observed significant differences in stromal fibrovascular abundance and composition accompanied by increased recruitment of F4/80(+) cell populations in T beta RII((fl/fl);PY;WC) mice when compared with T beta RII((fl/fl);PY) controls. The recruitment of F4/80(+) cells correlated with increased expression of known inflammatory genes including Cxcl1, Cxcl5, and Ptgs2 (cyclooxygenase-2). Notably, we also identified an enriched K5(+) dNp63(+) cell population in primary T beta RII((fl/fl);PY;WC) tumors and corresponding pulmonary metastases, suggesting that loss of TGF-beta signaling in this subset of carcinoma cells can contribute to metastasis. Together, our current results indicate that loss of TGF-beta signaling in mammary alveolar progenitors may affect tumor initiation, progression, and metastasis through regulation of both intrinsic cell signaling and adjacent stromal-epithelial interactions in vivo.
Chuaiphichai, Surawee; Rashbrook, Victoria S; Hale, Ashley B; Trelfa, Lucy; Patel, Jyoti; McNeill, Eileen; Lygate, Craig A; Channon, Keith M; Douglas, Gillian
2018-07-01
GTPCH (GTP cyclohydrolase 1, encoded by Gch1 ) is required for the synthesis of tetrahydrobiopterin; a critical regulator of endothelial NO synthase function. We have previously shown that mice with selective loss of Gch1 in endothelial cells have mild vascular dysfunction, but the consequences of endothelial cell tetrahydrobiopterin deficiency in vascular disease pathogenesis are unknown. We investigated the pathological consequence of Ang (angiotensin) II infusion in endothelial cell Gch1 deficient ( Gch1 fl/fl Tie2cre) mice. Ang II (0.4 mg/kg per day, delivered by osmotic minipump) caused a significant decrease in circulating tetrahydrobiopterin levels in Gch1 fl/fl Tie2cre mice and a significant increase in the Nω-nitro-L-arginine methyl ester inhabitable production of H 2 O 2 in the aorta. Chronic treatment with this subpressor dose of Ang II resulted in a significant increase in blood pressure only in Gch1 fl/fl Tie2cre mice. This finding was mirrored with acute administration of Ang II, where increased sensitivity to Ang II was observed at both pressor and subpressor doses. Chronic Ang II infusion in Gch1 fl/fl Tie2ce mice resulted in vascular dysfunction in resistance mesenteric arteries with an enhanced constrictor and decreased dilator response and medial hypertrophy. Altered vascular remodeling was also observed in the aorta with an increase in the incidence of abdominal aortic aneurysm formation in Gch1 fl/fl Tie2ce mice. These findings indicate a specific requirement for endothelial cell tetrahydrobiopterin in modulating the hemodynamic and structural changes induced by Ang II, through modulation of blood pressure, structural changes in resistance vessels, and aneurysm formation in the aorta. © 2018 The Authors.
Adapting BODIPYs to singlet oxygen production on silica nanoparticles.
Epelde-Elezcano, Nerea; Prieto-Montero, Ruth; Martínez-Martínez, Virginia; Ortiz, María J; Prieto-Castañeda, Alejandro; Peña-Cabrera, Eduardo; Belmonte-Vázquez, José L; López-Arbeloa, Iñigo; Brown, Ross; Lacombe, Sylvie
2017-05-31
A modified Stöber method is used to synthesize spherical core-shell silica nanoparticles (NPs) with an external surface functionalized by amino groups and with an average size around 50 nm. Fluorescent dyes and photosensitizers of singlet oxygen were fixed, either separately or conjointly, respectively in the core or in the shell. Rhodamines were encapsulated in the core with relatively high fluorescence quantum yields (Φ fl ≥ 0.3), allowing fluorescence tracking of the particles. Various photosensitizers of singlet oxygen (PS) were covalenty coupled to the shell, allowing singlet oxygen production. The stability of NP suspensions strongly deteriorated upon grafting the PS, affecting their apparent singlet oxygen quantum yields. Agglomeration of NPs depends both on the type and on the amount of grafted photosensitizer. New, lab-made, halogenated 4,4-difluoro-4-bora-3a,4a-diaza-s-indacenes (BODIPY) grafted to the NPs achieved higher singlet oxygen quantum yields (Φ Δ ∼ 0.35-0.40) than Rose Bengal (RB) grafted NPs (Φ Δ ∼ 0.10-0.27). Finally, we combined both fluorescence and PS functions in the same NP, namely a rhodamine in the silica core and a BODIPY or RB grafted in the shell, achieving the performance Φ fl ∼ 0.10-0.20, Φ Δ ∼ 0.16-0.25 with a single excitation wavelength. Thus, proper choice of the dyes, of their concentrations inside and on the NPs and the grafting method enables fine-tuning of singlet oxygen production and fluorescence emission.
EnviroAtlas -Tampa, FL- One Meter Resolution Urban Land Cover (2010)
The EnviroAtlas Tampa, FL land cover map was generated from USDA NAIP (National Agricultural Imagery Program) four band (red, green, blue and near infrared) aerial photography from April-May 2010 at 1 m spatial resolution. Eight land cover classes were mapped: impervious surface, soil and barren, grass and herbaceous, trees and forest, water, agriculture, woody wetland, and emergent wetland. The area mapped is defined by the US Census Bureau's 2010 Urban Statistical Area for Tampa, and includes the cities of Clearwater and St. Petersburg, as well as additional out-lying areas. An accuracy assessment using a stratified random sampling of 600 samples (100 per class) yielded an overall accuracy of 70.67 percent and an area weighted accuracy of 81.87 percent using a minimum mapping unit of 9 pixels (3x3 pixel window). This dataset was produced by the US EPA to support research and online mapping activities related to EnviroAtlas. EnviroAtlas (https://www.epa.gov/enviroatlas) allows the user to interact with a web-based, easy-to-use, mapping application to view and analyze multiple ecosystem services for the contiguous United States. The dataset is available as downloadable data (https://edg.epa.gov/data/Public/ORD/EnviroAtlas) or as an EnviroAtlas map service. Additional descriptive information about each attribute in this dataset can be found in its associated EnviroAtlas Fact Sheet (https://www.epa.gov/enviroatlas/enviroatlas-fact-sheets).
77 FR 74856 - Changes in Flood Hazard Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-18
... Resources, Whitehead Street, Suite 2798 Overseas Highway, 102, Key West, FL 33040. Marathon, FL 33050.... Marathon, FL 33050. Orange (FEMA Docket No.: B- City of Orlando (11- The Honorable Buddy Dyer, Permitting...
Phobic Anxiety and Plasma Levels of Global Oxidative Stress in Women
Hagan, Kaitlin A.; Wu, Tianying; Rimm, Eric B.; Eliassen, A. Heather; Okereke, Olivia I.
2015-01-01
Background and Objectives Psychological distress has been hypothesized to be associated with adverse biologic states such as higher oxidative stress and inflammation. Yet, little is known about associations between a common form of distress – phobic anxiety – and global oxidative stress. Thus, we related phobic anxiety to plasma fluorescent oxidation products (FlOPs), a global oxidative stress marker. Methods We conducted a cross-sectional analysis among 1,325 women (aged 43-70 years) from the Nurses’ Health Study. Phobic anxiety was measured using the Crown-Crisp Index (CCI). Adjusted least-squares mean log-transformed FlOPs were calculated across phobic categories. Logistic regression models were used to calculate odds ratios (OR) comparing the highest CCI category (≥6 points) vs. lower scores, across FlOPs quartiles. Results No association was found between phobic anxiety categories and mean FlOP levels in multivariable adjusted linear models. Similarly, in multivariable logistic regression models there were no associations between FlOPs quartiles and likelihood of being in the highest phobic category. Comparing women in the highest vs. lowest FlOPs quartiles: FlOP_360: OR=0.68 (95% CI: 0.40-1.15); FlOP_320: OR=0.99 (95% CI: 0.61-1.61); FlOP_400: OR=0.92 (95% CI: 0.52, 1.63). Conclusions No cross-sectional association was found between phobic anxiety and a plasma measure of global oxidative stress in this sample of middle-aged and older women. PMID:26635425
Assessment of femur length for fetal biometry in Malaysian pregnant women
NASA Astrophysics Data System (ADS)
Ramli, Ramzun Maizan; Adam, Noraina; Jaafar, Mohamad Suhaimi; Rahman, Azhar Abdul; Mustafa, Iskandar Shahrim; Radzi, Yasmin; Nordin, Suriani; Kamarudin, Izyani
2013-05-01
The fetal biometry assessment of femur length (FL) was developed in most countries to evaluate the foetus growth. In this study, the FL values for Malaysia population were determined. A prospective study was conducted and a number of 6501 pregnant women were involved with 12372 FL data were collected, performed at antenatal care clinic of Hospital Pulau Pinang, Malaysia. The SPSS software version 17 (regression analysis and paired sample t-test) were used for analysis. The FL values of this study were constructed and rapid FL growth rate in second trimester (2.59 mm/week) than third trimester (1.43 mm/week) was observed. By ethnicity, no significant difference (p ≥ 0.05) was found between the FL values for fetuses of Malay and Indian ethnic's mother (t = -2.042), however these two groups shows significantly (p < 0.05) higher values than those of Chinese ethnic's mother (t = 4.019, 4.083; accordingly). The FL values of Malaysian resulted as significant difference with the common reference FL values from USA and UK, and also with selected Asian populations (India, China, Korea and Japan). As conclusion, it is strong suggested that medical practitioner in Malaysia should avoid in using biometry references based on other population to avoid under- or over-estimation and for accurate assessment of the fetus growth. As this study involved local Malaysian fetuses, therefore the medical practitioner can use the FL values of this study as reference value for fetus biometry assessment in Malaysia.
46 CFR 7.100 - Florida Reefs and Keys from Miami, FL to Marquesas Keys, FL.
Code of Federal Regulations, 2014 CFR
2014-10-01
... latitude 24°27.7′ N. longitude 81°48.1′ W. (Key West Entrance Lighted Whistle Buoy); thence to Cosgrove... 46 Shipping 1 2014-10-01 2014-10-01 false Florida Reefs and Keys from Miami, FL to Marquesas Keys... TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.100 Florida Reefs and Keys from Miami, FL to...
46 CFR 7.100 - Florida Reefs and Keys from Miami, FL to Marquesas Keys, FL.
Code of Federal Regulations, 2012 CFR
2012-10-01
... latitude 24°27.7′ N. longitude 81°48.1′ W. (Key West Entrance Lighted Whistle Buoy); thence to Cosgrove... 46 Shipping 1 2012-10-01 2012-10-01 false Florida Reefs and Keys from Miami, FL to Marquesas Keys... TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.100 Florida Reefs and Keys from Miami, FL to...
46 CFR 7.100 - Florida Reefs and Keys from Miami, FL to Marquesas Keys, FL.
Code of Federal Regulations, 2010 CFR
2010-10-01
... latitude 24°27.7′ N. longitude 81°48.1′ W. (Key West Entrance Lighted Whistle Buoy); thence to Cosgrove... 46 Shipping 1 2010-10-01 2010-10-01 false Florida Reefs and Keys from Miami, FL to Marquesas Keys... TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.100 Florida Reefs and Keys from Miami, FL to...
46 CFR 7.100 - Florida Reefs and Keys from Miami, FL to Marquesas Keys, FL.
Code of Federal Regulations, 2011 CFR
2011-10-01
... latitude 24°27.7′ N. longitude 81°48.1′ W. (Key West Entrance Lighted Whistle Buoy); thence to Cosgrove... 46 Shipping 1 2011-10-01 2011-10-01 false Florida Reefs and Keys from Miami, FL to Marquesas Keys... TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.100 Florida Reefs and Keys from Miami, FL to...
46 CFR 7.100 - Florida Reefs and Keys from Miami, FL to Marquesas Keys, FL.
Code of Federal Regulations, 2013 CFR
2013-10-01
... latitude 24°27.7′ N. longitude 81°48.1′ W. (Key West Entrance Lighted Whistle Buoy); thence to Cosgrove... 46 Shipping 1 2013-10-01 2013-10-01 false Florida Reefs and Keys from Miami, FL to Marquesas Keys... TO THE PUBLIC BOUNDARY LINES Atlantic Coast § 7.100 Florida Reefs and Keys from Miami, FL to...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-22
...-1146; Airspace Docket No. 10-ASO-25] Proposed Amendment of Restricted Areas R-2907A and R-2907B, Lake George, FL; and R-2910, Pinecastle, FL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice... limits of restricted areas R-2907A and R-2907B, Lake George, FL; and restricted area R-2910, Pinecastle...