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Sample records for stabilization equipment essential

  1. Interim Stabilization Equipment Essential and Support Drawing Plan

    SciTech Connect

    HORNER, T.M.

    2000-10-16

    The purpose of this document is to list the Interim Stabilization equipment drawings that are classified as Essential or Support drawings. Essential Drawings are those drawings identified by the facility staff as necessary to directly support the safe operation of the facility or equipment. [CHG 2000a]. Support Drawings are those drawings identified by the facility staff that further describe the design details of structures, systems or components shown on essential drawings. [CHG 2000a].

  2. Interim Stabilization Equipment Essential and Support Drawing Plan

    SciTech Connect

    KOCH, M.R.

    1999-11-17

    The purpose of this document is to list the Interim Stabilization equipment drawings that are classified as Essential or Support drawings. Essential Drawings: Those drawings identified by the facility staff as necessary to directly support the safe operation of the facility or equipment. Support Drawings: Those drawings identified by the facility staff that further describe the design details of structures, systems or components shown on essential drawings.

  3. Interim Stabilization Equipment Essential and Support Drawing Plan

    SciTech Connect

    KOCH, M.R.

    1999-10-22

    The purpose of this document is to list the Interim Stabilization equipment drawings that are classified as Essential or Support drawings. Essential Drawings: Those drawings identified by the facility staff as necessary to directly support the safe operation of the facility or equipment. Support Drawings: Those drawings identified by the facility staff that further describe the design details of structures, systems or components shown on essential drawings.

  4. Characterization equipment essential drawing plan

    SciTech Connect

    WILSON, G.W.

    1999-05-18

    The purpose of this document is to list the Characterization equipment drawings that are classified as Essential Drawings. Essential Drawings: Are those drawings identified by the facility staff as necessary to directly support the safe operation of the facility or equipment (HNF 1997a). The Characterization equipment drawings identified in this report are deemed essential drawings as defined in HNF-PRO-242, Engineering Drawing Requirements (HNF 1997a). These drawings will be prepared, revised, and maintained per HNF-PRO-440, Engineering Document Change Control (HNF 1997b). All other Characterization equipment drawings not identified in this document will be considered Support drawings until the Characterization Equipment Drawing Evaluation Report is completed.

  5. Classroom Materials and Equipment--The Essentials.

    ERIC Educational Resources Information Center

    Texas Child Care, 1999

    1999-01-01

    Presents guidelines for buying classroom toys/equipment for child care settings. Lists examples of appropriate toys and equipment for infants, toddlers, preschoolers, and school-aged children in the following areas: action toys, art materials, audiovisual materials, balls, blocks and construction materials, books, discovery materials, dolls and…

  6. Essentials of Airway Management, Oxygenation, and Ventilation: Basic Equipment and Devices.

    PubMed

    Becker, Daniel E; Rosenberg, Morton B; Phero, James C

    2015-01-01

    Offices and outpatient dental facilities must be properly equipped with devices for airway management, oxygenation, and ventilation. Optimizing patient safety using crisis resource management involves the entire dental office team being familiar with airway rescue equipment. Basic equipment for oxygenation, ventilation, and airway management is mandated in the majority of U.S. dental offices, per state regulations. The immediate availability of this equipment is especially important during the administration of sedation and anesthesia, as well as the treatment of medical urgencies/emergencies. This article reviews basic equipment and devices essential in any dental practice, whether providing local anesthesia alone or in combination with procedural sedation. PMID:26168530

  7. Essentials of airway management, oxygenation, and ventilation: part 1: basic equipment and devices.

    PubMed

    Becker, Daniel E; Rosenberg, Morton B; Phero, James C

    2014-01-01

    Offices and outpatient dental facilities must be properly equipped with devices for airway management, oxygenation, and ventilation. Optimizing patient safety using crisis resource management (CRM) involves the entire dental office team being familiar with airway rescue equipment. Basic equipment for oxygenation, ventilation, and airway management is mandated in the majority of US dental offices per state regulations. The immediate availability of this equipment is especially important during the administration of sedation and anesthesia as well as the treatment of medical urgencies/emergencies. This article reviews basic equipment and devices essential in any dental practice whether providing local anesthesia alone or in combination with procedural sedation. Part 2 of this series will address advanced airway devices, including supraglottic airways and armamentarium for tracheal intubation and invasive airway procedures. PMID:24932982

  8. Essentials of airway management, oxygenation, and ventilation: part 1: basic equipment and devices.

    PubMed

    Becker, Daniel E; Rosenberg, Morton B; Phero, James C

    2014-01-01

    Offices and outpatient dental facilities must be properly equipped with devices for airway management, oxygenation, and ventilation. Optimizing patient safety using crisis resource management (CRM) involves the entire dental office team being familiar with airway rescue equipment. Basic equipment for oxygenation, ventilation, and airway management is mandated in the majority of US dental offices per state regulations. The immediate availability of this equipment is especially important during the administration of sedation and anesthesia as well as the treatment of medical urgencies/emergencies. This article reviews basic equipment and devices essential in any dental practice whether providing local anesthesia alone or in combination with procedural sedation. Part 2 of this series will address advanced airway devices, including supraglottic airways and armamentarium for tracheal intubation and invasive airway procedures.

  9. Developing COSHH Essentials: dermal exposure, personal protective equipment and first aid.

    PubMed

    Garrod, A N I; Rajan-Sithamparanadarajah, R

    2003-10-01

    The 'control banding' approach in COSHH Essentials combines the potential for harm with the potential for exposure by inhalation to band measures to control exposure at source, as generic strategies. These are simply adapted to specific tasks and circumstances to produce specific control advice. Where it is not possible or practical to use this control advice, the control bands can suggest adequate respiratory protective equipment using 'protection factors'. Proposals in the paper enable the user to identify the right level of respiratory protective equipment (RPE), and to begin selecting suitable RPE. Selection is made through a formatted questionnaire, enabling the user to give the right facts to the supplier. COSHH Essentials applies mainly to exposure by inhalation. However, skin exposure is very common and uptake via the skin can be an important contributor to body dose. This paper examines the factors concerning skin exposure, and the options for banding the potential for harm to the skin or via the skin. Proposals have then been made for dermal exposure control. Planning for emergencies is an important facet of risk control. Proposals are outlined to band chemical hazards for emergency planning according to a minimum of information, i.e. the danger symbol on a product label.

  10. Developing COSHH Essentials: dermal exposure, personal protective equipment and first aid.

    PubMed

    Garrod, A N I; Rajan-Sithamparanadarajah, R

    2003-10-01

    The 'control banding' approach in COSHH Essentials combines the potential for harm with the potential for exposure by inhalation to band measures to control exposure at source, as generic strategies. These are simply adapted to specific tasks and circumstances to produce specific control advice. Where it is not possible or practical to use this control advice, the control bands can suggest adequate respiratory protective equipment using 'protection factors'. Proposals in the paper enable the user to identify the right level of respiratory protective equipment (RPE), and to begin selecting suitable RPE. Selection is made through a formatted questionnaire, enabling the user to give the right facts to the supplier. COSHH Essentials applies mainly to exposure by inhalation. However, skin exposure is very common and uptake via the skin can be an important contributor to body dose. This paper examines the factors concerning skin exposure, and the options for banding the potential for harm to the skin or via the skin. Proposals have then been made for dermal exposure control. Planning for emergencies is an important facet of risk control. Proposals are outlined to band chemical hazards for emergency planning according to a minimum of information, i.e. the danger symbol on a product label. PMID:14530184

  11. SLOPE STABILITY EVALUATION AND EQUIPMENT SETBACK DISTANCES FOR BURIAL GROUND EXCAVATIONS

    SciTech Connect

    MCSHANE DS

    2010-03-25

    After 1970 Transuranic (TRU) and suspect TRU waste was buried in the ground with the intention that at some later date the waste would be retrieved and processed into a configuration for long term storage. To retrieve this waste the soil must be removed (excavated). Sloping the bank of the excavation is the method used to keep the excavation from collapsing and to provide protection for workers retrieving the waste. The purpose of this paper is to document the minimum distance (setback) that equipment must stay from the edge of the excavation to maintain a stable slope. This evaluation examines the equipment setback distance by dividing the equipment into two categories, (1) equipment used for excavation and (2) equipment used for retrieval. The section on excavation equipment will also discuss techniques used for excavation including the process of benching. Calculations 122633-C-004, 'Slope Stability Analysis' (Attachment A), and 300013-C-001, 'Crane Stability Analysis' (Attachment B), have been prepared to support this evaluation. As shown in the calculations the soil has the following properties: Unit weight 110 pounds per cubic foot; and Friction Angle (natural angle of repose) 38{sup o} or 1.28 horizontal to 1 vertical. Setback distances are measured from the top edge of the slope to the wheels/tracks of the vehicles and heavy equipment being utilized. The computer program utilized in the calculation uses the center of the wheel or track load for the analysis and this difference is accounted for in this evaluation.

  12. Essential Role of Duox in Stabilization of Drosophila Wing*

    PubMed Central

    Anh, Nguyen Thi Tu; Nishitani, Maiko; Harada, Shigeharu; Yamaguchi, Masamitsu; Kamei, Kaeko

    2011-01-01

    NADPH oxidase produces reactive oxygen species (ROS). Drosophila melanogaster has two homologs of NADPH oxidase, dNox and dDuox, with functions that remain unclear in vivo. To clarify these functions, two independent transgenic fly lines expressing dsRNA targeted for different portions of dDuox mRNA were used. In both flies, en-GAL4> UAS-dDuoxIR976–1145 and en-GAL4> UAS-dDuoxIR370–518, in which dDuox was knocked down selectively in the posterior area of the wing disc, the posterior compartment of the adult wings became paler and more fragile with wing veins that were indistinct by comparison with the anterior one. Fluorescence staining of the en-GAL4> UAS-dDuoxIR976–1145 adult wings revealed that the ROS concentration in the posterior compartment was significantly lower than that in the anterior compartment. Moreover, in these flies, the posterior compartment of the wing imaginal disc showed a greater number of apoptotic cells detected by immunostaining with anti-cleaved caspase-3 antibody than those in the anterior compartment. Respective knockdown of tyrosine hydroxylase or dopa-decarboxylase showed paler wing blades in the posterior compartment similar to the phenotype of dDuox-knockdown files. Along with this observation, analysis of the catecholic and dityrosine components in the wings of adult flies proved that dDuox plays important roles in the stabilization of the cuticle structure of the wings via tyrosine cross-linking, the sclerotization and melanization processes possibly through ROS production. These dDuox-knockdown fly lines would be useful tools for further studying dDuox functions during the development of Drosophila. PMID:21808060

  13. Stability of the Martian atmosphere: Is heterogeneous catalysis essential?

    NASA Technical Reports Server (NTRS)

    Atreya, Sushil K.; Gu, Zhen Gang

    1994-01-01

    A comprehensive homogeneous gas phase photochemical model is developed to study the problem of stability of the Martian atmosphere. The one-dimensional model extends from the ground up to 220 km, passing through the homopause at 125 km. The model thus couples the lower (neutral) atmosphere to the ionosphere above which provides significant downward flux of carbon monoxide and oxygen atoms. It is concluded on the basic of currently accepted values for globally and seasonally averaged water vapor abundance, dust opacity and the middle atmospheric eddy mixing coefficient, as well as the relevant laboratory data (particularly the temperature dependence of CO2 absorption cross section and the rate constant for CO+OH reaction), that the rate of re-formation of carbon dioxide exceeds its photolytic destruction rate by about 40%. Furthermore, it is found that this result is virtually independent of the choice of eddy mixing coefficient, unless its value in the middle atmosphere exceeds 10(exp 8) sq cm/sec or is far smaller than 10(exp 5)sq cm/sec, or the dust opacity, unless it exceeds unity, or the water vapor mixing ratio at the surface, unless it is far smaller (less than or = 1 ppm) or far greater (greater than or = 500 ppm) than the average value (approximately 150 ppm). Since none of these extremes represent globally and seasonally averaged conditions on Mars, we propose that the present model requires existence of a mechanism to throttle down the recycling rate of carbon dioxide on Mars. Therefore, it is suggested that a heterogeneous process which provides a sink to the species that participate in the recycling of CO2, i.e., H2O, H2O2, OH, CO or O, in particular, may be necessary to bring about the balance between the CO2 recycling rate and its photolytic destruction rate. Aerosols of dust or ice (pure or doped water or carbon dioxide ice present in the atmosphere of Mars) can provide the appropriate adsorption sites for the above heterogeneous process. Despite our

  14. Methods for thermal stability enhancement of leaf essential oils and their main constituents from indigenous cinnamon (Cinnamomum osmophloeum).

    PubMed

    Yeh, Hsin-Fu; Luo, Chi-Yuan; Lin, Chun-Ya; Cheng, Sen-Sung; Hsu, Yen-Ray; Chang, Shang-Tzen

    2013-07-01

    The thermal stability of leaf essential oils from various Cinnamomum osmophloeum and their constituents was investigated for the first time. The results indicated that trans-cinnamaldehyde (Cin) content in eugenol-free essential oil from C. osmophloeum was affected by high temperatures. The retention of Cin (RC) decreased to 17.4% after the essential oil was incubated for 8 h at 100 °C. In contrast, essential oils containing eugenol showed greater thermal stability. Seven kinds of antioxidants were added to Cin to improve its thermal stability. Among them, eugenol endowed Cin with the best thermal stability. We also investigated the influence of various amounts of eugenol on the thermal stability of both essential oil and Cin. Both essential oil and Cin showed excellent thermal stability when 0.62 and 2.60% (v/v) eugenol were added. In short, the thermal stability of essential oil and Cin could be effectively improved by adding appropriate amounts of eugenol.

  15. Stabilization of soybean oil during accelerated storage by essential oil of ferulago angulata boiss.

    PubMed

    Sadeghi, Ehsan; Mahtabani, Aidin; Etminan, Alireza; Karami, Farahnaz

    2016-02-01

    This study has been considered effect of Ferulago angulata essential oil on stabilizing soybean oil during accelerated storage. The essential oil was extracted by Clevenger-type apparatus. For analysis of the essential oil, GC/MS was used. Main components of the essential oil were monoterpene and sesquiterpene hydrocarbons. The essential oil of F. angulata at four concentrations, i.e. 125 (SBO-125), 250 (SBO-250), 500 (SBO-500) and SBO-Mixture (60 ppm TBHQ +60 ppm essential oil) were added to preheated refined soybean oil. TBHQ was used at 120 ppm as standard besides the control. Antioxidant activity index (AAI), free fatty acid (FFA) content, peroxide value (PV) and p-anisidine value (p-AnV) were served for appreciation of efficacy of F. angulata in stabilization of soybean oil. Results from different tests showed that SBO-mixture had highest effect and followed by SBO-TBHQ, SBO-250, SBO-125, SBO-500 and Ctrl. These results reveal F. angulata is a strong antioxidant and can be used instead of synthetic antioxidant.

  16. Equipment

    NASA Astrophysics Data System (ADS)

    Szumski, Michał

    This chapter describes the most important features of capillary electrophoretic equipment. A presentation of the important developments in high voltage power supplies for chip CE is followed by preparation of fused silica capillaries for use in CE. Detection systems that are used in capillary electrophoresis are widely described. Here, UV-Vis absorbance measurements are discussed including different types of detection cells—also those less popular (u-shaped, Z-shaped, mirror-coated). Fluorescence detection and laser-induced fluorescence detection are the most sensitive detection systems. Several LIF setups, such as collinear, orthogonal, confocal, and sheath-flow cuvette, are presented from the point of view of the sensitivity they can provide. Several electrochemical detectors for CE, such as conductivity, amperometric, and potentiometric, are also shown and their constructions discussed. CE-MS and much less known CE (CEC)-NMR systems are also described. The examples of automation and robotized CE systems together with their potential fields of application are also presented.

  17. DEVELOPMENT OF EQUIPMENT FOR THE RETRIEVAL & STABILIZATION & ENCAPSULATION OF RADIOACTIVE SLUDGE AT THE HANFORD SITE

    SciTech Connect

    ROOSENDAAL, G.D.

    2005-07-05

    This poster presentation describes and illustrates some of the equipment and tools that Fluor Hanford and BNG America have developed and designed to remove, transport, stabilize and encapsulate radioactive sludge from the K Basins at the Hanford nuclear site in Washington State, U.S.A. K Basins were built in the early 1950s to temporarily store irradiated nuclear fuel prior to chemical processing to remove plutonium for nuclear weapons. The sludge is the result of corrosion of these fuel elements and its removal is the final stage before the basin water can be drained and the basins decommissioned. The sludge is hydrogen-generating because of its uranium metal content and account has to be taken also of its heat generating capacity and criticality potential as it is moved from one containment to another. The paper describes all stages of sludge treatment from the use of vacuum wands to suck up the sludge, through consolidating the sludge in temporary underwater containers, transporting it though flexible, temporary pipe systems, acceleration of the corrosion of uranium to reduce hydrogen generation, measuring the fissile content and finally encapsulation in a cement grout. Emphasis is placed on the use of existing, transportable and temporary equipment. This not only saves initial costs but it also reduces the total amount of equipment needed to be disposed of as radioactive waste at the end of the job. The processes, equipment and tools described potentially have a broad applicability to nuclear site decommissioning and cleanup worldwide.

  18. Stability of nonfouling electroless nickel-polytetrafluoroethylene coatings after exposure to commercial dairy equipment sanitizers.

    PubMed

    Huang, Kang; Goddard, Julie M

    2015-09-01

    Application of nonfouling coatings on thermal processing equipment can improve operational efficiency. However, to enable effective commercial translation, a need exists for more comprehensive studies on the stability of nonfouling coatings after exposure to different sanitizers. In the current study, the influence of different commercial dairy equipment sanitizers on the nonfouling properties of stainless steel modified with electroless Ni-polytetrafluoroethylene (PTFE) coatings was determined. Surface properties, such as dynamic contact angle, surface energy, surface morphology, and elemental composition, were measured before and after the coupons were exposed to the sanitizers for 168 cleaning cycles. The fouling behavior of Ni-PTFE-modified stainless steel coupons after exposure was also evaluated by processing raw milk on a self-fabricated benchtop-scale plate heat exchanger. The results indicated that peroxide sanitizer had only minor effect on the Ni-PTFE-modified stainless steel surface, whereas chlorine- and iodine-based sanitizers influenced the surface properties drastically. The coupons after 168 cycles of exposure to peroxide sanitizer accumulated the least amount of fouling material (4.44±0.24mg/cm(2)) compared with the coupons exposed to the other 3 sanitizers. These observations indicated that the Ni-PTFE nonfouling coating retained antifouling properties after 168 cycles of exposure to peroxide-based sanitizer, supporting their potential application as nonfouling coatings for stainless steel dairy processing equipment.

  19. Thermal and oxidative stability of the Ocimum basilicum L. essential oil/β-cyclodextrin supramolecular system.

    PubMed

    Hădărugă, Daniel I; Hădărugă, Nicoleta G; Costescu, Corina I; David, Ioan; Gruia, Alexandra T

    2014-01-01

    Ocimum basilicum L. essential oil and its β-cyclodextrin (β-CD) complex have been investigated with respect to their stability against the degradative action of air/oxygen and temperature. This supramolecular system was obtained by a crystallization method in order to achieve the equilibrium of complexed-uncomplexed volatile compounds in an ethanol/water solution at 50 °C. Both the raw essential oil and its β-CD complex have been subjected to thermal and oxidative degradation conditions in order to evaluate the protective capacity of β-CD. The relative concentration of the O. basilicum L. essential oil compounds, as determined by GC-MS, varies accordingly with their sensitivity to the thermal and/or oxidative degradation conditions imposed. Furthermore, the relative concentration of the volatile O. basilicum L. compounds found in the β-CD complex is quite different in comparison with the raw material. An increase of the relative concentration of linalool oxide from 0.3% to 1.1%, in addition to many sesquiterpene oxides, has been observed. β-CD complexation of the O. basilicum essential oil modifies the relative concentration of the encapsulated volatile compounds. Thus, linalool was better encapsulated in β-CD, while methylchavicol (estragole) was encapsulated in β-CD at a concentration close to that of the raw essential oil. Higher relative concentrations from the degradation of the oxygenated compounds such as linalool oxide and aromadendren oxide were determined in the raw O. basilicum L. essential oil in comparison with the corresponding β-CD complex. For the first time, the protective capability of natural β-CD for labile basil essential oil compounds has been demonstrated.

  20. Thermal and oxidative stability of the Ocimum basilicum L. essential oil/β-cyclodextrin supramolecular system.

    PubMed

    Hădărugă, Daniel I; Hădărugă, Nicoleta G; Costescu, Corina I; David, Ioan; Gruia, Alexandra T

    2014-01-01

    Ocimum basilicum L. essential oil and its β-cyclodextrin (β-CD) complex have been investigated with respect to their stability against the degradative action of air/oxygen and temperature. This supramolecular system was obtained by a crystallization method in order to achieve the equilibrium of complexed-uncomplexed volatile compounds in an ethanol/water solution at 50 °C. Both the raw essential oil and its β-CD complex have been subjected to thermal and oxidative degradation conditions in order to evaluate the protective capacity of β-CD. The relative concentration of the O. basilicum L. essential oil compounds, as determined by GC-MS, varies accordingly with their sensitivity to the thermal and/or oxidative degradation conditions imposed. Furthermore, the relative concentration of the volatile O. basilicum L. compounds found in the β-CD complex is quite different in comparison with the raw material. An increase of the relative concentration of linalool oxide from 0.3% to 1.1%, in addition to many sesquiterpene oxides, has been observed. β-CD complexation of the O. basilicum essential oil modifies the relative concentration of the encapsulated volatile compounds. Thus, linalool was better encapsulated in β-CD, while methylchavicol (estragole) was encapsulated in β-CD at a concentration close to that of the raw essential oil. Higher relative concentrations from the degradation of the oxygenated compounds such as linalool oxide and aromadendren oxide were determined in the raw O. basilicum L. essential oil in comparison with the corresponding β-CD complex. For the first time, the protective capability of natural β-CD for labile basil essential oil compounds has been demonstrated. PMID:25550747

  1. Thermal and oxidative stability of the Ocimum basilicum L. essential oil/β-cyclodextrin supramolecular system

    PubMed Central

    Hădărugă, Nicoleta G; Costescu, Corina I; David, Ioan; Gruia, Alexandra T

    2014-01-01

    Summary Ocimum basilicum L. essential oil and its β-cyclodextrin (β-CD) complex have been investigated with respect to their stability against the degradative action of air/oxygen and temperature. This supramolecular system was obtained by a crystallization method in order to achieve the equilibrium of complexed–uncomplexed volatile compounds in an ethanol/water solution at 50 °C. Both the raw essential oil and its β-CD complex have been subjected to thermal and oxidative degradation conditions in order to evaluate the protective capacity of β-CD. The relative concentration of the O. basilicum L. essential oil compounds, as determined by GC–MS, varies accordingly with their sensitivity to the thermal and/or oxidative degradation conditions imposed. Furthermore, the relative concentration of the volatile O. basilicum L. compounds found in the β-CD complex is quite different in comparison with the raw material. An increase of the relative concentration of linalool oxide from 0.3% to 1.1%, in addition to many sesquiterpene oxides, has been observed. β-CD complexation of the O. basilicum essential oil modifies the relative concentration of the encapsulated volatile compounds. Thus, linalool was better encapsulated in β-CD, while methylchavicol (estragole) was encapsulated in β-CD at a concentration close to that of the raw essential oil. Higher relative concentrations from the degradation of the oxygenated compounds such as linalool oxide and aromadendren oxide were determined in the raw O. basilicum L. essential oil in comparison with the corresponding β-CD complex. For the first time, the protective capability of natural β-CD for labile basil essential oil compounds has been demonstrated. PMID:25550747

  2. Sde2: A novel nuclear protein essential for telomeric silencing and genomic stability in Schizosaccharomyces pombe

    SciTech Connect

    Sugioka-Sugiyama, Rie; Sugiyama, Tomoyasu

    2011-03-18

    Research highlights: {yields} Sde2 is essential for telomere silencing. {yields} Sde2 is involved in the maintenance of genomic stability. {yields} Sde2 promotes the recruitment of SHREC, a histone deacetylase complex, to telomeres. -- Abstract: Telomeres, specialized domains assembled at the ends of linear chromosomes, are essential for genomic stability in eukaryotes. The formation and maintenance of telomeres are governed by numerous factors such as telomeric repeats, telomere-binding proteins, heterochromatin proteins, and telomerase. Here, we report Sde2, a novel nuclear protein essential for telomeric silencing and genomic stability in the fission yeast Schizosaccharomyces pombe. A deficiency in sde2 results in the derepression of the ura4{sup +} gene inserted near telomeric repeats, and the noncoding transcripts from telomeric regions accumulate in sde2{Delta} cells. The loss of Sde2 function compromises transcriptional silencing at telomeres, and this silencing defect is accompanied by increased levels of acetylated histone H3K14 and RNA polymerase II occupancy at telomeres as well as reduced recruitment of the SNF2 ATPase/histone deacetylase-containing complex SHREC to telomeres. Deletion of sde2 also leads to a higher frequency of mitotic minichromosome loss, and sde2{Delta} cells often form asci that contain spores in abnormal numbers, shapes, or both. In addition, sde2{Delta} cells are highly sensitive to several stresses, including high/low temperatures, bleomycin, which induces DNA damage, and thiabendazole, a microtubule-destabilizing agent. Furthermore, Sde2 genetically interacts with the telomere regulators Taz1, Pof3, and Ccq1. These findings demonstrate that Sde2 cooperates with other telomere regulators to maintain functional telomeres, thereby preventing genomic instability.

  3. [Systemic emulsions. 2. Use of different methods of formulation: the effect of essential oils of thyme on stability].

    PubMed

    Passet, J; Laget, J P; Nielloud, F; Delonca, H

    1994-01-01

    As part of an ongoing investigation on emulsifying techniques, we studied the influence of different essential oils from Thymus vulgaris on emulsion stability. All four chimiotypes tested (geraniol, linalol, carvacrol, and thymol) caused a marked decrease in stability. This instability cannot be explained by a change in the hydrophilic lipophilic balance since the HLBc of the new oil phase (essential oil + paraffine oil) was not significantly different from that of paraffine alone. PMID:7884636

  4. Effect of downhole assembly and cutter geometry on stability of drillstrings equipped with polycrystalline diamond compact (PDC) cutters

    SciTech Connect

    Elsayed, M.A.; Dareing, D.W.; Dupuy, C.A.

    1996-11-01

    Stability of drillstrings equipped with PDC cutters depends on many factors such as the design of the drillstring, design of the cutter, and formation type. In this paper, the authors show that the drill pipe plays a minor role in stability in comparison with that of the drill collars. They also show that the number of cutter blades affects the location of the stability pockets, while their spacing affects the size of these pockets. Using this data, a combination of drill collar and cutter design can be used to provide operating speeds resulting in maximum stability of the drillstring.

  5. Stabilization of sunflower oil with Carum copticum Benth & Hook essential oil.

    PubMed

    Hashemi, Mohammad Bagher; Niakousari, Mehrdad; Saharkhiz, Mohammad Jamal; Eskandari, Mohammad Hadi

    2014-01-01

    In this study, application of various concentrations (0.025%, 0.05% and 0.075%) of Carum copticum essential oil (EO) were examined on oxidative stability of sunflower oil and there were compared to Butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) during storage at 37 and 47 °C. The main compounds of EO were identified as thymol (50.07%), γ- terpinene (23.92%) and p-cymene (22.9%). Peroxide value (PV), anisidine value (AnV) and thiobarbituric acid (TBA) value measurement in sunflower oil showed that all concentrations of EO had antioxidant effect in comparison to BHA and BHT. Samples added with EO at 0.075% were the most stable during storage at both temperatures (P < 0.05). Furthermore, Totox value, antioxidant activity (AA), stabilization factor (F) and antioxidant power (AOP) determination confirmed efficacy of this EO as antioxidant in sunflower oil. EO also was able to reduce the stable free radical 2, 2-diphenyl-1-picrylhydrazyl (DPPH) with a 50% inhibition concentration (IC50) of 20.3 ± 0.9 μg/mL. Therefore, the results indicate that EO could be used as a natural antioxidant in food lipids.

  6. Hybrid nanomaterial for stabilizing the antibiofilm activity of Eugenia carryophyllata essential oil.

    PubMed

    Grumezescu, Alexandru Mihai; Chifiriuc, Mariana Carmen; Saviuc, Crina; Grumezescu, Valentina; Hristu, Radu; Mihaiescu, Dan Eduard; Stanciu, George A; Andronescu, Ecaterina

    2012-12-01

    The aim of the present study was to demonstrate that Fe(3)O(4)/oleic acid core/shell nanostructures could be used as systems for stabilizing the Eugenia carryophyllata essential oil (EO) on catheter surface pellicles, in order to improve their resistance to fungal colonization. EO microwave assisted extraction was performed in a Neo-Clevenger (related) device and its chemical composition was settled by GC-MS analysis. Fe(3)O(4)/oleic acid-core/shell nanoparticles (NP) were obtained by a precipitation method under microwave condition. High resolution transmission electron microscopy (HR-TEM) was used as a primary characterization method. The NPs were processed to achieve a core/shell/EO coated-shell nanosystem further used for coating the inner surface of central venous catheter samples. The tested fungal strains have been recently isolated from different clinical specimens. The biofilm architecture was assessed by confocal laser scanning microscopy (CLSM). Our results claim the usage of hybrid nanomaterial (core/shell/coated-shell) for the stabilization of E. carryophyllata EO, which prevented or inhibited the fungal biofilm development on the functionalized catheter, highlighting the opportunity of using these nanosystems to obtain improved, anti-biofilm coatings for biomedical applications. PMID:22949098

  7. Improving Efficiency with 3-D Imaging: Technology Essential in Removing Plutonium Processing Equipment from Plutonium Finishing Plant Gloveboxes

    SciTech Connect

    Crow, Stephen H.; Kyle, Richard N.; Minette, Michael J.

    2008-09-01

    The Plutonium Finishing Plant at Hanford, Washington began operations in 1949 to process plutonium and plutonium products. Its primary mission was to produce plutonium metal, fabricate weapons parts, and stabilize reactive materials. These operations, and subsequent activities, were performed in remote production lines, consisting primarily of hundreds of gloveboxes. Over the years these gloveboxes and processes have been continuously modified. The plant is currently inactive and Fluor Hanford has been tasked to clean out contaminated equipment and gloveboxes from the facility so it can be demolished in the near future. Approximately 100 gloveboxes at PFP have been cleaned out in the past four years and about 90 gloveboxes remain to be cleaned out. Because specific commitment dates for this work have been established with the State of Washington and other entities, it is important to adopt work practices that increase the safety and speed of this effort. The most recent work practice to be adopted by Fluor Hanford D&D workers is the use of 3-D models to improve the efficiency of cleaning out radioactive gloveboxes at the plant. The use of 3-D models has significantly improved the work planning process by providing workers with a clear image of glovebox construction and composition, which is then used to determine cleanout methods and work sequences. The 3-D visual products enhance safety by enabling workers to more easily identify hazards and implement controls. In addition, the ability to identify and target the removal of radiological materials early in the D&D process provides substantial dose reduction for the workers.

  8. Influence of spike lavender (Lavandula latifolia Med.) essential oil in the quality, stability and composition of soybean oil during microwave heating.

    PubMed

    Rodrigues, Nuno; Malheiro, Ricardo; Casal, Susana; Asensio-S-Manzanera, M Carmen; Bento, Albino; Pereira, José Alberto

    2012-08-01

    Lipids oxidation is one of the main factors leading to quality losses in foods. Its prevention or delay could be obtained by the addition of antioxidants. In this sense the present work intend to monitor the protective effects of Lavandula latifolia essential oil during soybean oil microwave heating. To achieve the proposed goal quality parameters (free acidity, peroxide value, specific coefficients of extinction and ΔK), fatty acids profile, tocopherols and tocotrienols composition, antioxidant activity and oxidative stability were evaluated in soybean oil with and without spike lavender essential oils (EO) submitted to different microwave heating exposure times (1, 3, 5, 10 and 15 min; 1000 Watt) with a standard domestic microwave equipment. Microwave heating induced severe quality and composition losses, mainly above 3 min of microwave heating, regardless the sample tested. However, spike lavender EO addition counteracts the oxidation comparatively to control oils, by presenting enhanced values in quality parameters. A higher protection in unsaturated fatty acids loss was also observed as well as a higher antioxidant activity and oxidative stability. The microwave heating effects were clearly different in the samples with essential oils addition, allowing discrimination from plain soybean oils by a principal component analysis, being also capable to discriminate the different heating times tested within each sample.

  9. Histone Chaperone Asf1 Plays an Essential Role in Maintaining Genomic Stability in Fission Yeast

    PubMed Central

    Tanae, Katsuhiro; Horiuchi, Tomitaka; Matsuo, Yuzy; Katayama, Satoshi; Kawamukai, Makoto

    2012-01-01

    The histone H3-H4 chaperone Asf1 is involved in chromatin assembly (or disassembly), histone exchange, regulation of transcription, and chromatin silencing in several organisms. To investigate the essential functions of Asf1 in Schizosaccharomyces pombe, asf1-ts mutants were constructed by random mutagenesis using PCR. One mutant (asf1-33(ts)) was mated with mutants in 77 different kinase genes to identify synthetic lethal combinations. The asf1-33 mutant required the DNA damage checkpoint factors Chk1 and Rad3 for its survival at the restrictive temperature. Chk1, but not Cds1, was phosphorylated in the asf1-33 mutant at the restrictive temperature, indicating that the DNA damage checkpoint was activated in the asf1-33 mutant. DNA damage occured in the asf1-33 mutant, with degradation of the chromosomal DNA observed through pulse-field gel electrophoresis and the formation of Rad22 foci. Sensitivity to micrococcal nuclease in the asf1-33 mutant was increased compared to the asf1+ strain at the restrictive temperature, suggesting that asf1 mutations also caused a defect in overall chromatin structure. The Asf1-33 mutant protein was mislocalized and incapable of binding histones. Furthermore, histone H3 levels at the centromeric outer repeat region were decreased in the asf1-33 mutant and heterochromatin structure was impaired. Finally, sim3, which encodes a CenH3 histone chaperone, was identified as a strong suppressor of the asf1-33 mutant. Taken together, these results clearly indicate that Asf1 plays an essential role in maintaining genomic stability in S. pombe. PMID:22291963

  10. Stabilization of emulsion and butter like products containing essential fatty acids using kalonji seeds extract and curcuminoids.

    PubMed

    Rege, Sameera A; Momin, Shamim A; Bhowmick, Dipti N; Pratap, Amit A

    2012-01-01

    Owing to the tendency of essential fatty acids (EFAs) to undergo autoxidation, their storage becomes a key problem. Generally, they are stabilized by synthetic antioxidants like TBHQ that are toxic in nature. Recently many studies were reported where these EFAs are stabilized by natural antioxidants. In the present study, curcuminoids and kalonji seeds ethanol extract (KEE) were used to stabilize these EFAs in refined sunflower oil (RSFO), water-in-oil (w/o) emulsion and butter like products (BLPs). In RSFO, though curcuminoids alone exerted pro-oxidant effect, KEE and curcuminoids showed synergistic antioxidant activity that was comparable to TBHQ. KEE exhibited good antioxidant activity in emulsions and BLPs, providing fine physical properties like slipping point, dropping point and spreadability. EFAs increased the nutritional value of BLPs and antioxidants added for their stabilization provided their medicinal benefits. PMID:22188801

  11. A Comprehensive Review of Rollover Accidents Involving Vehicles Equipped with Electronic Stability Control (ESC) Systems

    PubMed Central

    Padmanaban, Jeya; Shields, Leland E.; Scheibe, Robert R.; Eyges, Vitaly E.

    2008-01-01

    This study investigated 478 police accident reports from 9 states to examine and characterize rollover crashes involving ESC-equipped vehicles. The focus was on the sequence of critical events leading to loss of control and rollover, and the interactions between the accident, driver, and environment. Results show that, while ESC is effective in reducing loss of control leading to certain rollover crashes, its effectiveness is diminished in others, particularly when the vehicle departs the roadway or when environmental factors such as slick road conditions or driver factors such as speeding, distraction, fatigue, impairment, or overcorrection are present. PMID:19026219

  12. An intein-mediated modulation of protein stability system and its application to study human cytomegalovirus essential gene function

    PubMed Central

    Pan, Deng; Xuan, Baoqin; Sun, Yamei; Huang, Shaowu; Xie, Maorong; Bai, Yadan; Xu, Wenjia; Qian, Zhikang

    2016-01-01

    Functional analysis of the essential proteins encoded by human cytomegalovirus (HCMV) is hindered by the lack of complementing systems. To overcome this difficulty, we have established a novel approach, termed the intein-mediated modulation of protein stability (imPS), in which a destabilizing domain and part of a split intein are fused to the essential protein. The growth of the mutant virus can then be regulated by the degradation and splicing of the protein. We found that an ultrafast gp41-1 split intein was able to rescue or degrade the protein of interest (POI) by removing or adding a strong degron through protein splicing. As a result, the function of the POI was turned on or off during the process. Using HCMV essential gene IE1/IE2, we confirmed that imPS worked remarkably well in conditionally regulating protein stability during viral infection. This conditional approach is likely to be applicable for dissecting the gene functions of HCMV or other viruses. PMID:27188239

  13. Operational stability of rubidium and cesium frequency standards. [analysis of equipment performance at NASA tracking stations

    NASA Technical Reports Server (NTRS)

    Lavery, J. E.

    1972-01-01

    In the course of testing various rubidium and cesium frequency standards under operational conditions for use in NASA tracking stations, about 55 unit-years of relative frequency measurements for averaging times from 10 to 10 to the 7th power have been accumulated at Goddard Space Flight Center (GSFC). Statistics on the behavior of rubidium and cesium standards under controlled laboratory conditions have been published, but it was not known to what extent the lesser controlled environments of NASA tracking stations affected the performance of the standards. The purpose of this report is to present estimates of the frequency stability of rubidium and cesium frequency standards under operational conditions based on the data accumulated at GSFC.

  14. Characterization of polymorph transformations that decrease the stability of tablets containing the WHO essential drug mebendazole.

    PubMed

    Brits, Marius; Liebenberg, Wilna; de Villiers, Melgardt M

    2010-03-01

    This study investigated the influence of moisture and heat on the stability of mebendazole polymorph C in tablets. The polymorphic forms of mebendazole display significant differences in solubility and therapeutic efficacy and form C is preferred clinically due to its optimal bioavailability and reduced toxicity. An accelerated stability study of the polymorphs revealed that the Johnson-Mehl-Avrami-Erofeyev-Kolmogorov (JMAEK) model best described the kinetics of the solid-state transformation of form C to A. Rate constants obtained using this model was used to calculated half-lives and shelf lives of products stored under ICH conditions of 30 degrees C + 65% RH and 40 degrees C + 75% RH. Results showed that form C was converted to the thermodynamic stable, least soluble form A with increased temperatures and moisture, and at constant temperature and relative humidity this transformation was significantly increased when trace amounts of form A was present in the tablets. Four out of the seven products tested contained trace amounts of form A. In some tablets, the transformation to form A was so quick that it reduced the shelf life to less than 1 month. The tablet dissolution of these products was reduced to such an extent that it did not comply with USP and FDA specifications. PMID:19691117

  15. Stability of Minimum Essential Medium functionality despite L-glutamine decomposition.

    PubMed

    Jagušić, Maja; Forčić, Dubravko; Brgles, Marija; Kutle, Leonida; Šantak, Maja; Jergović, Mladen; Kotarski, Ljerka; Bendelja, Krešo; Halassy, Beata

    2016-08-01

    L-Glutamine (L-Gln) instability in liquid media is a well-known fact. Also, negative effect of ammonia, one of the L-Gln degradation products, on viability of many cell cultures and on replication of different viruses has been described. However, negative effects of ammonia have been reported in doses excessively exceeding those that could be generated in regularly used liquid culture media due to spontaneous L-Gln breakdown (below 2 mM). Traditional virus vaccine production processes have been established and registered involving L-Gln containing media use. Eventual culture media replacement in the regular production process belongs to the major regulative changes that require substantial financial expenses. The aim of this study was to evaluate the effect of storage of Minimum Essential Media with Hanks salts on their relevant biological functions during virus vaccine production process in relation to L-Gln decrease. Our results show a cell type dependent effect of spontaneous L-Gln degradation during medium storage. They also suggest that for cell cultures used in measles, mumps, and rubella virus production the media retain their functionality in respect to cell viability or virus growth over a certain time window despite L-Gln degradation.

  16. Enhancing stability of essential oils by microencapsulation for preservation of button mushroom during postharvest.

    PubMed

    Alikhani-Koupaei, Majid; Mazlumzadeh, Meisam; Sharifani, Mohamadmehdi; Adibian, Mohamad

    2014-09-01

    Fresh button mushrooms (Agaricus bisporus L.) are sensitive to browning, water loss, and microbial attack. The short shelf-life of mushrooms is an impediment to the distribution and marketing of the fresh product. Essential oils outstand as an alternative to chemical preservatives and their use in foods meets the demands of consumers for natural products. To resolve controlled release of oil and increase in antioxidant and antimicrobial activities, the oil was incorporated into microcapsules. Effects of microcapsulated thyme (Thymus vulgaris L.) and rosemary (Rosmarinus officinalis L.) on quality of fresh button mushroom were compared. Physicochemical qualities were evaluated during 15 days of storage at 4 ± 0.5°C. All treatments prevented product weight loss and decrease in polyphenoloxidase and peroxidase activities during storage. Color and firmness, microbiological analysis, and total phenolic content caused the least change. With use of microencapsulated oils, mushrooms were within acceptable limits during 10 days of storage. Microencapsulated rosemary oil produced the highest beneficial effects and has potential to improve quality of button mushrooms and extend shelf-life. PMID:25473510

  17. Rasip1 is essential to blood vessel stability and angiogenic blood vessel growth.

    PubMed

    Koo, Yeon; Barry, David M; Xu, Ke; Tanigaki, Keiji; Davis, George E; Mineo, Chieko; Cleaver, Ondine

    2016-04-01

    Cardiovascular function depends on patent, continuous and stable blood vessel formation by endothelial cells (ECs). Blood vessel development initiates by vasculogenesis, as ECs coalesce into linear aggregates and organize to form central lumens that allow blood flow. Molecular mechanisms underlying in vivo vascular 'tubulogenesis' are only beginning to be unraveled. We previously showed that the GTPase-interacting protein called Rasip1 is required for the formation of continuous vascular lumens in the early embryo. Rasip1(-/-) ECs exhibit loss of proper cell polarity and cell shape, disrupted localization of EC-EC junctions and defects in adhesion of ECs to extracellular matrix. In vitro studies showed that Rasip1 depletion in cultured ECs blocked tubulogenesis. Whether Rasip1 is required in blood vessels after their initial formation remained unclear. Here, we show that Rasip1 is essential for vessel formation and maintenance in the embryo, but not in quiescent adult vessels. Rasip1 is also required for angiogenesis in three models of blood vessel growth: in vitro matrix invasion, retinal blood vessel growth and directed in vivo angiogenesis assays. Rasip1 is thus necessary in growing embryonic blood vessels, postnatal angiogenic sprouting and remodeling, but is dispensable for maintenance of established blood vessels, making it a potential anti-angiogenic therapeutic target.

  18. Enhancing stability of essential oils by microencapsulation for preservation of button mushroom during postharvest

    PubMed Central

    Alikhani-Koupaei, Majid; Mazlumzadeh, Meisam; Sharifani, Mohamadmehdi; Adibian, Mohamad

    2014-01-01

    Fresh button mushrooms (Agaricus bisporus L.) are sensitive to browning, water loss, and microbial attack. The short shelf-life of mushrooms is an impediment to the distribution and marketing of the fresh product. Essential oils outstand as an alternative to chemical preservatives and their use in foods meets the demands of consumers for natural products. To resolve controlled release of oil and increase in antioxidant and antimicrobial activities, the oil was incorporated into microcapsules. Effects of microcapsulated thyme (Thymus vulgaris L.) and rosemary (Rosmarinus officinalis L.) on quality of fresh button mushroom were compared. Physicochemical qualities were evaluated during 15 days of storage at 4 ± 0.5°C. All treatments prevented product weight loss and decrease in polyphenoloxidase and peroxidase activities during storage. Color and firmness, microbiological analysis, and total phenolic content caused the least change. With use of microencapsulated oils, mushrooms were within acceptable limits during 10 days of storage. Microencapsulated rosemary oil produced the highest beneficial effects and has potential to improve quality of button mushrooms and extend shelf-life. PMID:25473510

  19. The Effect of Oregano and Cinnamon Essential Oils on Fermentation Quality and Aerobic Stability of Field Pea Silages.

    PubMed

    Soycan-Önenç, Sibel; Koc, Fisun; Coşkuntuna, Levent; Özdüven, M Levent; Gümüş, Tuncay

    2015-09-01

    This study was performed to determine the effect of field pea silages which were the organic acid (OA) alternative of oregano and cinnamon essential oils on fermentation quality and aerobic stability. Whole crop pea was harvested at full pod stage and wilted in the laboratory at the 48 h. The chopped pea was mixed and divided into equal portions allocated to five groups: CON (non-treated), distilled water, denoted as control group; OA group, a mixture of 60% formic acid, 20% sodium formate and 20% water applied at a rate of 5 g/kg fresh forage (Silofarm Liquid, Farmavet); origanum (ORE) group, Origanum onites essential oil at 400 mg/kg fresh forage; cinnamon (CIN) group, cinnamon essential oil at 400 mg/kg fresh forage; origanum+cinnamon (ORECIN) group, a mixture of ORE and CIN applied at an equal rate of 400 mg/kg fresh forage. Cinnamon decreased acetic acid (AA), ammonia nitrogen (NH3-N) and weight loss (WL) at the end of 60 days silage. Crude protein (CP) and dry matter (DM) increased by cinnamon essential oil. Yeasts were not detected in any treatments, including the control, after 7 days of air exposure. The CO2 amount decreased and the formation mold was inhibited in the aerobic period by the addition of cinnamon oil. Oregano did not show a similar effect, but when it was used with cinnamon, it showed synergic effect on AA and during aerobic period, it showed antagonistic effect on mold formation and DM losses. It was found in this study that cinnamon can be an alternative to organic acids. PMID:26323518

  20. The Effect of Oregano and Cinnamon Essential Oils on Fermentation Quality and Aerobic Stability of Field Pea Silages.

    PubMed

    Soycan-Önenç, Sibel; Koc, Fisun; Coşkuntuna, Levent; Özdüven, M Levent; Gümüş, Tuncay

    2015-09-01

    This study was performed to determine the effect of field pea silages which were the organic acid (OA) alternative of oregano and cinnamon essential oils on fermentation quality and aerobic stability. Whole crop pea was harvested at full pod stage and wilted in the laboratory at the 48 h. The chopped pea was mixed and divided into equal portions allocated to five groups: CON (non-treated), distilled water, denoted as control group; OA group, a mixture of 60% formic acid, 20% sodium formate and 20% water applied at a rate of 5 g/kg fresh forage (Silofarm Liquid, Farmavet); origanum (ORE) group, Origanum onites essential oil at 400 mg/kg fresh forage; cinnamon (CIN) group, cinnamon essential oil at 400 mg/kg fresh forage; origanum+cinnamon (ORECIN) group, a mixture of ORE and CIN applied at an equal rate of 400 mg/kg fresh forage. Cinnamon decreased acetic acid (AA), ammonia nitrogen (NH3-N) and weight loss (WL) at the end of 60 days silage. Crude protein (CP) and dry matter (DM) increased by cinnamon essential oil. Yeasts were not detected in any treatments, including the control, after 7 days of air exposure. The CO2 amount decreased and the formation mold was inhibited in the aerobic period by the addition of cinnamon oil. Oregano did not show a similar effect, but when it was used with cinnamon, it showed synergic effect on AA and during aerobic period, it showed antagonistic effect on mold formation and DM losses. It was found in this study that cinnamon can be an alternative to organic acids.

  1. The Effect of Oregano and Cinnamon Essential Oils on Fermentation Quality and Aerobic Stability of Field Pea Silages

    PubMed Central

    Soycan-Önenç, Sibel; Koc, Fisun; Coşkuntuna, Levent; Özdüven, M. Levent; Gümüş, Tuncay

    2015-01-01

    This study was performed to determine the effect of field pea silages which were the organic acid (OA) alternative of oregano and cinnamon essential oils on fermentation quality and aerobic stability. Whole crop pea was harvested at full pod stage and wilted in the laboratory at the 48 h. The chopped pea was mixed and divided into equal portions allocated to five groups: CON (non-treated), distilled water, denoted as control group; OA group, a mixture of 60% formic acid, 20% sodium formate and 20% water applied at a rate of 5 g/kg fresh forage (Silofarm Liquid, Farmavet); origanum (ORE) group, Origanum onites essential oil at 400 mg/kg fresh forage; cinnamon (CIN) group, cinnamon essential oil at 400 mg/kg fresh forage; origanum+cinnamon (ORECIN) group, a mixture of ORE and CIN applied at an equal rate of 400 mg/kg fresh forage. Cinnamon decreased acetic acid (AA), ammonia nitrogen (NH3-N) and weight loss (WL) at the end of 60 days silage. Crude protein (CP) and dry matter (DM) increased by cinnamon essential oil. Yeasts were not detected in any treatments, including the control, after 7 days of air exposure. The CO2 amount decreased and the formation mold was inhibited in the aerobic period by the addition of cinnamon oil. Oregano did not show a similar effect, but when it was used with cinnamon, it showed synergic effect on AA and during aerobic period, it showed antagonistic effect on mold formation and DM losses. It was found in this study that cinnamon can be an alternative to organic acids. PMID:26323518

  2. Essential Roles of BCCIP in Mouse Embryonic Development and Structural Stability of Chromosomes

    PubMed Central

    Lu, Huimei; Huang, Yi-Yuan; Mehrotra, Sonam; Droz-Rosario, Roberto; Liu, Jingmei; Bhaumik, Mantu; White, Eileen; Shen, Zhiyuan

    2011-01-01

    BCCIP is a BRCA2- and CDKN1A(p21)-interacting protein that has been implicated in the maintenance of genomic integrity. To understand the in vivo functions of BCCIP, we generated a conditional BCCIP knockdown transgenic mouse model using Cre-LoxP mediated RNA interference. The BCCIP knockdown embryos displayed impaired cellular proliferation and apoptosis at day E7.5. Consistent with these results, the in vitro proliferation of blastocysts and mouse embryonic fibroblasts (MEFs) of BCCIP knockdown mice were impaired considerably. The BCCIP deficient mouse embryos die before E11.5 day. Deletion of the p53 gene could not rescue the embryonic lethality due to BCCIP deficiency, but partially rescues the growth delay of mouse embryonic fibroblasts in vitro. To further understand the cause of development and proliferation defects in BCCIP-deficient mice, MEFs were subjected to chromosome stability analysis. The BCCIP-deficient MEFs displayed significant spontaneous chromosome structural alterations associated with replication stress, including a 3.5-fold induction of chromatid breaks. Remarkably, the BCCIP-deficient MEFs had a ∼20-fold increase in sister chromatid union (SCU), yet the induction of sister chromatid exchanges (SCE) was modestly at 1.5 fold. SCU is a unique type of chromatid aberration that may give rise to chromatin bridges between daughter nuclei in anaphase. In addition, the BCCIP-deficient MEFs have reduced repair of irradiation-induced DNA damage and reductions of Rad51 protein and nuclear foci. Our data suggest a unique function of BCCIP, not only in repair of DNA damage, but also in resolving stalled replication forks and prevention of replication stress. In addition, BCCIP deficiency causes excessive spontaneous chromatin bridges via the formation of SCU, which can subsequently impair chromosome segregations in mitosis and cell division. PMID:21966279

  3. p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification.

    PubMed

    Pieters, Tim; Goossens, Steven; Haenebalcke, Lieven; Andries, Vanessa; Stryjewska, Agata; De Rycke, Riet; Lemeire, Kelly; Hochepied, Tino; Huylebroeck, Danny; Berx, Geert; Stemmler, Marc P; Wirth, Dagmar; Haigh, Jody J; van Hengel, Jolanda; van Roy, Frans

    2016-08-01

    E-cadherin-mediated cell-cell adhesion is critical for naive pluripotency of cultured mouse embryonic stem cells (mESCs). E-cadherin-depleted mESC fail to downregulate their pluripotency program and are unable to initiate lineage commitment. To further explore the roles of cell adhesion molecules during mESC differentiation, we focused on p120 catenin (p120ctn). Although one key function of p120ctn is to stabilize and regulate cadherin-mediated cell-cell adhesion, it has many additional functions, including regulation of transcription and Rho GTPase activity. Here, we investigated the role of mouse p120ctn in early embryogenesis, mESC pluripotency and early fate determination. In contrast to the E-cadherin-null phenotype, p120ctn-null mESCs remained pluripotent, but their in vitro differentiation was incomplete. In particular, they failed to form cystic embryoid bodies and showed defects in primitive endoderm formation. To pinpoint the underlying mechanism, we undertook a structure-function approach. Rescue of p120ctn-null mESCs with different p120ctn wild-type and mutant expression constructs revealed that the long N-terminal domain of p120ctn and its regulatory domain for RhoA were dispensable, whereas its armadillo domain and interaction with E-cadherin were crucial for primitive endoderm formation. We conclude that p120ctn is not only an adaptor and regulator of E-cadherin, but is also indispensable for proper lineage commitment. PMID:27556156

  4. p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification

    PubMed Central

    Haenebalcke, Lieven; Stryjewska, Agata; De Rycke, Riet; Lemeire, Kelly; Huylebroeck, Danny; Stemmler, Marc P.; Wirth, Dagmar; Haigh, Jody J.; van Hengel, Jolanda; van Roy, Frans

    2016-01-01

    E-cadherin-mediated cell-cell adhesion is critical for naive pluripotency of cultured mouse embryonic stem cells (mESCs). E-cadherin-depleted mESC fail to downregulate their pluripotency program and are unable to initiate lineage commitment. To further explore the roles of cell adhesion molecules during mESC differentiation, we focused on p120 catenin (p120ctn). Although one key function of p120ctn is to stabilize and regulate cadherin-mediated cell-cell adhesion, it has many additional functions, including regulation of transcription and Rho GTPase activity. Here, we investigated the role of mouse p120ctn in early embryogenesis, mESC pluripotency and early fate determination. In contrast to the E-cadherin-null phenotype, p120ctn-null mESCs remained pluripotent, but their in vitro differentiation was incomplete. In particular, they failed to form cystic embryoid bodies and showed defects in primitive endoderm formation. To pinpoint the underlying mechanism, we undertook a structure-function approach. Rescue of p120ctn-null mESCs with different p120ctn wild-type and mutant expression constructs revealed that the long N-terminal domain of p120ctn and its regulatory domain for RhoA were dispensable, whereas its armadillo domain and interaction with E-cadherin were crucial for primitive endoderm formation. We conclude that p120ctn is not only an adaptor and regulator of E-cadherin, but is also indispensable for proper lineage commitment. PMID:27556156

  5. Implementation of an ex situ stabilization technique at the Sand Springs superfund site to solidify and stabilize acid tar sludges involving a quick-lime based stabilization process and innovative equipment design

    SciTech Connect

    McManus, R.W.; Grajczak, P.; Wilcoxson, J.C.; Webster, S.D.

    1997-12-31

    An old refinery site was safely remediated a year before schedule and for 25% less than final engineering estimates for the stabilization remedy thanks to energetic project management and innovative design involving ex situ stabilization/solidification of acid tar sludges. A quicklime based process, Dispersion by Chemical Reaction (DCR{trademark}), was employed to solidify and stabilize (SS) over 103,000 cubic meters (135,000 cubic yards) of petroleum waste, mostly acidic tarry sludge. The SS process was selected over competing methods because it afforded minimal volume increase, could readily achieve Record of Decision (ROD) specified physical and chemical treatment goals, could be implemented with treatment equipment that minimized emissions, and could be performed with low reagent usage and at low cost. To ensure treatment goals were achieved and an accelerated schedule met, a custom designed and fabricated transportable treatment unit (TTU) was employed to implement the process. The treated material was visually soil-like in character, it was left in stockpiles for periods of time, and it was placed and compacted in the on site landfill using standard earth-moving equipment.

  6. Effect of Echinophora platyloba DC. essential oil and lycopene on the stability of pasteurized cream obtained from cow milk

    PubMed Central

    Ehsani, Ali; Hashemi, Mohammad; Hosseini Jazani, Nima; Aliakbarlu, Javad; Shokri, Sajad; Naghibi, Seyedeh Samane

    2016-01-01

    The present study was carried out to enhance shelf life of pasteurized cream using Echinophora platyloba essential oil (EEO) and lycopene. For this purpose, two concentrations of EEO (0.10% and 0.50%) and lycopene (20 and 50 ppm) alone and together as combinations were added in pasteurized creams and analyzed for microbial characteristics, sensorial properties and lipid stability during storage at 4 ˚C and 25 ˚C for 14 days. Results of microbial and chemical analyses of experimental pasteurized creams showed that pasteurized creams treated with combinations of the EEO and lycopene in their higher concentrations had the best microbial and chemical properties and the most stability than control during storage (p < 0.05). Results of sensorial evaluation demonstrated that all treatments had favorable overall acceptability, even though, the best sensorial properties were observed in creams with combinations of EEO and lycopene in their lower concentrations. Therefore, based on the results of the present study, application of EEO and lycopene as natural preservatives is especially recommend in high fat dairy products such as butter and cream. PMID:27482359

  7. Effect of Echinophora platyloba DC. essential oil and lycopene on the stability of pasteurized cream obtained from cow milk.

    PubMed

    Ehsani, Ali; Hashemi, Mohammad; Hosseini Jazani, Nima; Aliakbarlu, Javad; Shokri, Sajad; Naghibi, Seyedeh Samane

    2016-01-01

    The present study was carried out to enhance shelf life of pasteurized cream using Echinophora platyloba essential oil (EEO) and lycopene. For this purpose, two concentrations of EEO (0.10% and 0.50%) and lycopene (20 and 50 ppm) alone and together as combinations were added in pasteurized creams and analyzed for microbial characteristics, sensorial properties and lipid stability during storage at 4 ˚C and 25 ˚C for 14 days. Results of microbial and chemical analyses of experimental pasteurized creams showed that pasteurized creams treated with combinations of the EEO and lycopene in their higher concentrations had the best microbial and chemical properties and the most stability than control during storage (p < 0.05). Results of sensorial evaluation demonstrated that all treatments had favorable overall acceptability, even though, the best sensorial properties were observed in creams with combinations of EEO and lycopene in their lower concentrations. Therefore, based on the results of the present study, application of EEO and lycopene as natural preservatives is especially recommend in high fat dairy products such as butter and cream. PMID:27482359

  8. Transmission of Hepatitis C Virus Among People Who Inject Drugs: Viral Stability and Association With Drug Preparation Equipment

    PubMed Central

    Doerrbecker, Juliane; Behrendt, Patrick; Mateu-Gelabert, Pedro; Ciesek, Sandra; Riebesehl, Nina; Wilhelm, Corinne; Steinmann, Joerg; Pietschmann, Thomas; Steinmann, Eike

    2013-01-01

    Background. Hepatitis C virus (HCV) transmission among people who inject drugs remains a challenging public health problem. We investigated the risk of HCV transmission by analyzing the direct association of HCV with filters, water to dilute drugs, and water containers. Methods. Experiments were designed to replicate practices by people who inject drugs and include routinely used injection equipment. HCV stability in water was assessed by inoculation of bottled water with HCV. Viral association with containers was investigated by filling the containers with water, inoculating the water with HCV, emptying the water, and refilling the container with fresh water. Transmission risk associated with drug preparation filters was determined after drawing virus through a filter and incubating the filter to release infectious particles. Results. HCV can survive for up to 3 weeks in bottled water. Water containers present a risk for HCV transmission, as infectious virions remained associated with water containers after washing. Physical properties of the water containers determined the degree of HCV contamination after containers were refilled with water. HCV was also associated with filter material, in which around 10% of the viral inoculum was detectable. Conclusions. This study demonstrates the potential risk of HCV transmission among injection drug users who share water, filters, and water containers and will help to define public health interventions to reduce HCV transmission. PMID:23129759

  9. Disulfide-Mediated Stabilization of the IκB Kinase Binding Domain of NF-κB Essential Modulator (NEMO)

    PubMed Central

    2015-01-01

    Human NEMO (NF-κB essential modulator) is a 419 residue scaffolding protein that, together with catalytic subunits IKKα and IKKβ, forms the IκB kinase (IKK) complex, a key regulator of NF-κB pathway signaling. NEMO is an elongated homodimer comprising mostly α-helix. It has been shown that a NEMO fragment spanning residues 44–111, which contains the IKKα/β binding site, is structurally disordered in the absence of bound IKKβ. Herein we show that enforcing dimerization of NEMO1–120 or NEMO44–111 constructs through introduction of one or two interchain disulfide bonds, through oxidation of the native Cys54 residue and/or at position 107 through a Leu107Cys mutation, induces a stable α-helical coiled-coil structure that is preorganized to bind IKKβ with high affinity. Chemical and thermal denaturation studies showed that, in the context of a covalent dimer, the ordered structure was stabilized relative to the denatured state by up to 3 kcal/mol. A full-length NEMO-L107C protein formed covalent dimers upon treatment of mammalian cells with H2O2. Furthermore, NEMO-L107C bound endogenous IKKβ in A293T cells, reconstituted TNF-induced NF-κB signaling in NEMO-deficient cells, and interacted with TRAF6. Our results indicate that the IKKβ binding domain of NEMO possesses an ordered structure in the unbound state, provided that it is constrained within a dimer as is the case in the constitutively dimeric full-length NEMO protein. The stability of the NEMO coiled coil is maintained by strong interhelix interactions in the region centered on residue 54. The disulfide-linked constructs we describe herein may be useful for crystallization of NEMO’s IKKβ binding domain in the absence of bound IKKβ, thereby facilitating the structural characterization of small-molecule inhibitors. PMID:25400026

  10. Preferential solubilization behaviours and stability of some phenolic-bearing essential oils formulated in different microemulsion systems.

    PubMed

    Edris, A E; Malone, C F R

    2012-10-01

    The solubilization behaviour of a number of essential oils (EOs) containing volatile phenolic constituents was investigated in five different micellar solutions. These oils include clove bud (Eugenia caryophyllata), thyme (Thymus serpyllum) and oregano (Thymus capitatus). Ternary and pseudo-ternary phase diagrams were constructed to assess the ability for microemulsion formation and dilutability of each system using non-ionic surfactants. Results showed that Tween 20 (T20) was more suitable to solubilize these oils compared with Tween 80 (T80). Clove EO was found to be easily microemulsifiable compared with the other EOs, whereas oregano showed the least tendency to form a microemulsion. Particle sizes measured at different dilution lines ranged between 5.9 and 16.9 nm. The chemical composition of each EO was revealed by gas chromatography and was correlated with the observed solubilization behaviour. The presence of solubilization enhancers like poly-ols and short-chain alcohols improved solubilization of all EOs; however, establishment of new dilution lines was controlled by EO type. Physical stability assessment showed that all microemulsions were stable against alternate freeze/thaw cycles which extended for 1 week. On the contrary, each system showed different temperature sensitivity in the thermal stress assessment. The results of this investigation can be useful in fabrication of thermodynamically stable aqueous system carrying aromatic and bioactive phenolics for different applications in personal hygiene, cosmetic, fragrance and pharmaceutical products. PMID:22738164

  11. The comparative efficacy of stabilized stannous fluoride dentifrice, peroxide/baking soda dentifrice and essential oil mouthrinse for the prevention of gingivitis.

    PubMed

    Beiswanger, B B; McClanahan, S F; Bartizek, R D; Lanzalaco, A C; Bacca, L A; White, D J

    1997-01-01

    This double-blind parallel-design clinical study compared the efficacy of a stabilized stannous fluoride dentifrice (Crest Plus Gum Care), baking soda and peroxide (NaF) dentifrice (Mentadent), and essential oil mouthrinse (Listerine) to a conventional NaF dentifrice (Crest) for the control of plaque, gingivitis and gingival bleeding over six months. Following an initial baseline examination and stratification, subjects received a complete oral prophylaxis and were distributed assigned test products. Following three and six months, subjects re-visited the clinic for examinations. Evaluations at baseline and at 3 and 6 months included soft tissue status. Löe-Silness gingivitis/gingival bleeding, Silness-Löe plaque and dental stain. Results subsequent to six months of product use were as follows: At six months, the stabilized stannous fluoride dentifrice was observed to produce statistically significant 17.5% reductions in gingivitis and 27.5% reductions in gingival bleeding relative to the NaF dentifrice. The combination of sodium fluoride dentifrice and essential oil mouthrinse produced statistically significant reductions of 7.4% in gingivitis and 10.8% in plaque as compared with the NaF dentifrice. The stabilized stannous fluoride dentifrice produced statistically significant reductions in both gingivitis (10.8%) and gingival bleeding (23.0%) relative to the combination of sodium fluoride dentifrice and essential oil mouthrinse. The baking soda and peroxide (NaF) dentifrice did not provide reductions in gingivitis, plaque or gingival bleeding as compared with the conventional NaF dentifrice. The stabilized stannous fluoride dentifrice provided statistically significant reductions in gingivitis as compared with the baking soda and peroxide dentifrice following six months of use, and both the essential oil mouthrinse and stabilized stannous fluoride dentifrice provided statistically significant reductions in gingivitis as compared with the baking soda and

  12. The comparative efficacy of stabilized stannous fluoride dentifrice, peroxide/baking soda dentifrice and essential oil mouthrinse for the prevention of gingivitis.

    PubMed

    Beiswanger, B B; McClanahan, S F; Bartizek, R D; Lanzalaco, A C; Bacca, L A; White, D J

    1997-01-01

    This double-blind parallel-design clinical study compared the efficacy of a stabilized stannous fluoride dentifrice (Crest Plus Gum Care), baking soda and peroxide (NaF) dentifrice (Mentadent), and essential oil mouthrinse (Listerine) to a conventional NaF dentifrice (Crest) for the control of plaque, gingivitis and gingival bleeding over six months. Following an initial baseline examination and stratification, subjects received a complete oral prophylaxis and were distributed assigned test products. Following three and six months, subjects re-visited the clinic for examinations. Evaluations at baseline and at 3 and 6 months included soft tissue status. Löe-Silness gingivitis/gingival bleeding, Silness-Löe plaque and dental stain. Results subsequent to six months of product use were as follows: At six months, the stabilized stannous fluoride dentifrice was observed to produce statistically significant 17.5% reductions in gingivitis and 27.5% reductions in gingival bleeding relative to the NaF dentifrice. The combination of sodium fluoride dentifrice and essential oil mouthrinse produced statistically significant reductions of 7.4% in gingivitis and 10.8% in plaque as compared with the NaF dentifrice. The stabilized stannous fluoride dentifrice produced statistically significant reductions in both gingivitis (10.8%) and gingival bleeding (23.0%) relative to the combination of sodium fluoride dentifrice and essential oil mouthrinse. The baking soda and peroxide (NaF) dentifrice did not provide reductions in gingivitis, plaque or gingival bleeding as compared with the conventional NaF dentifrice. The stabilized stannous fluoride dentifrice provided statistically significant reductions in gingivitis as compared with the baking soda and peroxide dentifrice following six months of use, and both the essential oil mouthrinse and stabilized stannous fluoride dentifrice provided statistically significant reductions in gingivitis as compared with the baking soda and

  13. Subunit CydX of Escherichia coli cytochrome bd ubiquinol oxidase is essential for assembly and stability of the di-heme active site.

    PubMed

    Hoeser, Jo; Hong, Sangjin; Gehmann, Gerfried; Gennis, Robert B; Friedrich, Thorsten

    2014-05-01

    Cytochrome bd ubiquinol oxidase uses the electron transport from ubiquinol to oxygen to establish a proton gradient across the membrane. The enzyme complex consists of subunits CydA and B and contains two b- and one d-type hemes as cofactors. Recently, it was proposed that a third subunit named CydX is essential for the function of the complex. Here, we show that CydX is indeed a subunit of purified Escherichia coli cytochrome bd oxidase and that the small protein is needed either for the assembly or the stability of the active site di-heme center and, thus, is essential for oxidase activity.

  14. Performance of rabbits and oxidative stability of muscle tissues as affected by dietary supplementation with oregano essential oil.

    PubMed

    Botsoglou, N A; Florou-Paneri, P; Christaki, E; Giannenas, I; Spais, A B

    2004-06-01

    The effect of dietary supplementation with oregano essential oil on the performance of rabbits, and the susceptibility of the produced raw and thermally treated muscle tissue to lipid oxidation during refrigerated storage, were investigated. A total of 96 weaned rabbits were separated into four equal groups with three subgroups each. One group was given the basal diet and served as control, two groups were administered diets supplemented with oregano essential oil at levels of 100 and 200 mg/kg diet, whereas the remaining group was given a diet supplemented with alpha-tocopheryl acetate at 200 mg/kg. During the 42-day experimental period, body weight and feed intake were recorded weekly and the feed conversion ratio was calculated. Feeding the experimental diets to rabbits, performance parameters were not affected. Therefore, dietary oregano essential oil exerted no growth-promoting effect on rabbits. With increased supplementation of oregano essential oil, malondialdehyde values decreased in both raw and thermally treated muscles during refrigerated storage. This finding suggests that dietary oregano essential oil exerted a significant antioxidant effect. Dietary supplementation of oregano essential oil at the level of 200 mg/kg was more effective in delaying lipid oxidation compared with the level of 100 mg/kg, but inferior to dietary supplementation of 200 mg alpha-tocopheryl acetate per kg. This study indirectly provides evidence that antioxidant compounds occurring in oregano essential oil were absorbed by the rabbit and increased the antioxidative capacity of tissues. PMID:15264670

  15. Effect of Oregano Essential Oil (Origanum vulgare subsp. hirtum) on the Storage Stability and Quality Parameters of Ground Chicken Breast Meat.

    PubMed

    Al-Hijazeen, Marwan; Lee, Eun Joo; Mendonca, Aubrey; Ahn, Dong Uk

    2016-06-07

    A study was conducted to investigate the effect of oregano essential oil on the oxidative stability and color of raw and cooked chicken breast meats. Five treatments, including (1) control (none added); (2) 100 ppm oregano essential oil; (3) 300 ppm oregano essential oil; (4) 400 ppm oregano essential oil; and (5) 5 ppm butylated hydroxyanisole (BHA), were prepared with ground boneless, skinless chicken breast meat and used for both raw and cooked meat studies. For raw meat study, samples were individually packaged in oxygen-permeable bags and stored in a cold room (4 °C) for 7 days. For cooked meat study, the raw meat samples were vacuum-packaged in oxygen-impermeable vacuum bags and then cooked in-bag to an internal temperature of 75 °C. After cooling to room temperature, the cooked meats were repackaged in new oxygen-permeable bags and then stored at 4 °C for 7 days. Both raw and cooked meats were analyzed for lipid and protein oxidation, volatiles, and color at 0, 3, and 7 days of storage. Oregano essential oil significantly reduced (p < 0.05) lipid and protein oxidation, and improved color stability of raw and cooked meat. However, oregano oil at 400 ppm showed the strongest effect for all these parameters. Hexanal was the major aldehyde, which was decreased significantly (p < 0.05) by oregano oil treatment, in cooked meat. Overall, oregano essential oil at 100-400 ppm levels could be a good preservative that can replace the synthetic antioxidant in chicken meat.

  16. Effect of Oregano Essential Oil (Origanum vulgare subsp. hirtum) on the Storage Stability and Quality Parameters of Ground Chicken Breast Meat.

    PubMed

    Al-Hijazeen, Marwan; Lee, Eun Joo; Mendonca, Aubrey; Ahn, Dong Uk

    2016-01-01

    A study was conducted to investigate the effect of oregano essential oil on the oxidative stability and color of raw and cooked chicken breast meats. Five treatments, including (1) control (none added); (2) 100 ppm oregano essential oil; (3) 300 ppm oregano essential oil; (4) 400 ppm oregano essential oil; and (5) 5 ppm butylated hydroxyanisole (BHA), were prepared with ground boneless, skinless chicken breast meat and used for both raw and cooked meat studies. For raw meat study, samples were individually packaged in oxygen-permeable bags and stored in a cold room (4 °C) for 7 days. For cooked meat study, the raw meat samples were vacuum-packaged in oxygen-impermeable vacuum bags and then cooked in-bag to an internal temperature of 75 °C. After cooling to room temperature, the cooked meats were repackaged in new oxygen-permeable bags and then stored at 4 °C for 7 days. Both raw and cooked meats were analyzed for lipid and protein oxidation, volatiles, and color at 0, 3, and 7 days of storage. Oregano essential oil significantly reduced (p < 0.05) lipid and protein oxidation, and improved color stability of raw and cooked meat. However, oregano oil at 400 ppm showed the strongest effect for all these parameters. Hexanal was the major aldehyde, which was decreased significantly (p < 0.05) by oregano oil treatment, in cooked meat. Overall, oregano essential oil at 100-400 ppm levels could be a good preservative that can replace the synthetic antioxidant in chicken meat. PMID:27338486

  17. Effect of Oregano Essential Oil (Origanum vulgare subsp. hirtum) on the Storage Stability and Quality Parameters of Ground Chicken Breast Meat

    PubMed Central

    Al-Hijazeen, Marwan; Lee, Eun Joo; Mendonca, Aubrey; Ahn, Dong Uk

    2016-01-01

    A study was conducted to investigate the effect of oregano essential oil on the oxidative stability and color of raw and cooked chicken breast meats. Five treatments, including (1) control (none added); (2) 100 ppm oregano essential oil; (3) 300 ppm oregano essential oil; (4) 400 ppm oregano essential oil; and (5) 5 ppm butylated hydroxyanisole (BHA), were prepared with ground boneless, skinless chicken breast meat and used for both raw and cooked meat studies. For raw meat study, samples were individually packaged in oxygen-permeable bags and stored in a cold room (4 °C) for 7 days. For cooked meat study, the raw meat samples were vacuum-packaged in oxygen-impermeable vacuum bags and then cooked in-bag to an internal temperature of 75 °C. After cooling to room temperature, the cooked meats were repackaged in new oxygen-permeable bags and then stored at 4 °C for 7 days. Both raw and cooked meats were analyzed for lipid and protein oxidation, volatiles, and color at 0, 3, and 7 days of storage. Oregano essential oil significantly reduced (p < 0.05) lipid and protein oxidation, and improved color stability of raw and cooked meat. However, oregano oil at 400 ppm showed the strongest effect for all these parameters. Hexanal was the major aldehyde, which was decreased significantly (p < 0.05) by oregano oil treatment, in cooked meat. Overall, oregano essential oil at 100–400 ppm levels could be a good preservative that can replace the synthetic antioxidant in chicken meat. PMID:27338486

  18. Experimental Verification of the Rudder-Free Stability Theory for an Airplane Model Equipped with Rudders Having Negative Floating Tendency and Negligible Friction

    NASA Technical Reports Server (NTRS)

    McKinney, Marion O.; Maggin, Bernard

    1944-01-01

    An investigation has been made in the Langley free-flight tunnel to obtain an experimental verification of the theoretical rudder-free stability characteristics of an airplane model equipped with conventional rudders having negative floating tendencies and negligible friction. The model used in the tests was equipped with a conventional single vertical tail having rudder area 40 percent of the vertical tail area. The model was tested both in free flight and mounted on a strut that allowed freedom only in yaw. Tests were made with three different amounts of rudder aerodynamic balance and with various values of mass, moment of inertia, and center-of-gravity location of the rudder. Most of the stability derivatives required for the theoretical calculations were determined from forced and free-oscillation tests of the particular model tested. The theoretical analysis showed that the rudder-free motions of an airplane consist largely of two oscillatory modes - a long-period oscillation somewhat similar to the normal rudder-fixed oscillation and a short-period oscillation introduced only when the rudder is set free. It was found possible in the tests to create lateral instability of the rudder-free short-period mode by large values of rudder mass parameters even though the rudder-fixed condition was highly stable. The results of the tests and calculation indicated that for most present-day airplanes having rudders of negative floating tendency, the rudder-free stability characteristics may be examined by simply considering the dynamic lateral stability using the value of the directional-stability parameter Cn(sub p) for the rudder-free condition in the conventional controls-fixed lateral-stability equations. For very large airplanes having relatively high values of the rudder mass parameters with respect to the rudder aerodynamic parameters, however, analysis of the rudder-free stability should be made with the complete equations of motion. Good agreement between

  19. The antioxidant status and oxidative stability of muscle from lambs receiving oral administration of Artemisia herba alba and Rosmarinus officinalis essential oils.

    PubMed

    Aouadi, Dorra; Luciano, Giuseppe; Vasta, Valentina; Nasri, Saida; Brogna, Daniela M R; Abidi, Sourour; Priolo, Alessandro; Salem, Hichem Ben

    2014-06-01

    The effect of the dietary supplementation to lambs of essential oils (EOs) from rosemary (Rosmarinus officinalis) and artemisia (Artemisia herba alba) on the antioxidant status of muscle and on meat oxidative stability was studied. Eighteen Barbarine lambs were divided into 3 groups and for 95days received oat hay and concentrates. One group (C) was not supplemented, while the other two groups received 400mg/kg of EOs from rosemary (R400) or artemisia (A400). Both EOs possessed antioxidant properties and their oral administration improved the reducing and radical scavenging capacity of the muscle compared to the C treatment (P<0.01). Nevertheless, supplementing EOs did not exert protection against lipid oxidation and did not affect the colour stability in meat over 7days of aerobic storage.

  20. Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection

    PubMed Central

    Seu, Lillian; Sabbaj, Steffanie; Duverger, Alexandra; Wagner, Frederic; Anderson, Joshua C.; Davies, Elizabeth; Wolschendorf, Frank; Willey, Christopher D.; Saag, Michael S.; Goepfert, Paul

    2015-01-01

    ABSTRACT The extreme stability of the latent HIV-1 reservoir in the CD4+ memory T cell population prevents viral eradication with current antiretroviral therapy. It has been demonstrated that homeostatic T cell proliferation and clonal expansion of latently infected T cells due to viral integration into specific genes contribute to this extraordinary reservoir stability. Nevertheless, given the constant exposure of the memory T cell population to specific antigen or bystander activation, this reservoir stability seems remarkable, unless it is assumed that latent HIV-1 resides exclusively in memory T cells that recognize rare antigens. Another explanation for the stability of the reservoir could be that the latent HIV-1 reservoir is associated with an unresponsive T cell phenotype. We demonstrate here that host cells of latent HIV-1 infection events were functionally altered in ways that are consistent with the idea of an anergic, unresponsive T cell phenotype. Manipulations that induced or mimicked an anergic T cell state promoted latent HIV-1 infection. Kinome analysis data reflected this altered host cell phenotype at a system-wide level and revealed how the stable kinase activity changes networked to stabilize latent HIV-1 infection. Protein-protein interaction networks generated from kinome data could further be used to guide targeted genetic or pharmacological manipulations that alter the stability of latent HIV-1 infection. In summary, our data demonstrate that stable changes to the signal transduction and transcription factor network of latently HIV-1 infected host cells are essential to the ability of HIV-1 to establish and maintain latent HIV-1 infection status. IMPORTANCE The extreme stability of the latent HIV-1 reservoir allows the infection to persist for the lifetime of a patient, despite completely suppressive antiretroviral therapy. This extreme reservoir stability is somewhat surprising, since the latently HIV-1 infected CD4+ memory T cells that

  1. The Influence of Process Equipment on the Properties of Suspension Plasma Sprayed Yttria-Stabilized Zirconia Coatings

    NASA Astrophysics Data System (ADS)

    Marr, Michael; Waldbillig, David; Kesler, Olivera

    2013-03-01

    Suspension plasma-sprayed YSZ coatings were deposited at lab-scale and production-type facilities to investigate the effect of process equipment on coating properties. The target application for these coatings is solid oxide fuel cell (SOFC) electrolytes; hence, dense microstructures with low permeability values were preferred. Both facilities had the same torch but different suspension feeding systems, torch robots, and substrate holders. The lab-scale facility had higher torch-substrate relative speeds compared with the production-type facility. On porous stainless steel substrates, permeabilities and microstructures were comparable for coatings from both facilities, and no segmentation cracks were observed. Coating permeability was further reduced by increasing substrate temperatures during deposition or reducing suspension feed rates. On SOFC cathode substrates, coatings made in the production-type facility had higher permeabilities and more segmentation cracks compared with coatings made in the lab-scale facility. Increased cracking in coatings from the production-type facility was likely caused mainly by its lower torch-substrate relative speed.

  2. Feasibility study of a passive aeration reactor equipped with vertical pipes for compost stabilization of cow manure.

    PubMed

    Sylla, Youssouf Boundou; Kuroda, Masao; Yamada, Masayuki; Matsumoto, Naoko

    2006-10-01

    Pilot-scale composting was carried out with cow manure to evaluate the performances of two passive aeration systems: a conventional passive aeration system equipped with horizontal pipes and an unusual passive aeration method based on air delivery by means of vertical pipes. The effects of both types of passive aeration apparatus were investigated in order to determine the degree of composting rate by continuously monitoring temperature, moisture content, organic matter, electrical conductivity, pH and C/N ratio in the piles. Temperatures in the range of thermophily (55-65 degrees C) were reached in all runs within 1-2 days then lasting for about 1 week, a span long enough for pathogen abatement. Results suggest that passive aeration carried out by vertical pipes is more effective for air delivery into compost piles than conventional passive aeration of air adduction with horizontal pipes. The variation in the number of vertical pipes was revealed to be an important parameter for the control of composting rate and temperature. Composting rates estimated from the heat balance equation were substantially in agreement with those computed through the conversion ratio of total organic matter decrement. The conversion ratios and composting rates obtained in this study using passive aeration with vertical pipes were well aligned with those found using forced air delivery systems.

  3. Feasibility study of a passive aeration reactor equipped with vertical pipes for compost stabilization of cow manure.

    PubMed

    Sylla, Youssouf Boundou; Kuroda, Masao; Yamada, Masayuki; Matsumoto, Naoko

    2006-10-01

    Pilot-scale composting was carried out with cow manure to evaluate the performances of two passive aeration systems: a conventional passive aeration system equipped with horizontal pipes and an unusual passive aeration method based on air delivery by means of vertical pipes. The effects of both types of passive aeration apparatus were investigated in order to determine the degree of composting rate by continuously monitoring temperature, moisture content, organic matter, electrical conductivity, pH and C/N ratio in the piles. Temperatures in the range of thermophily (55-65 degrees C) were reached in all runs within 1-2 days then lasting for about 1 week, a span long enough for pathogen abatement. Results suggest that passive aeration carried out by vertical pipes is more effective for air delivery into compost piles than conventional passive aeration of air adduction with horizontal pipes. The variation in the number of vertical pipes was revealed to be an important parameter for the control of composting rate and temperature. Composting rates estimated from the heat balance equation were substantially in agreement with those computed through the conversion ratio of total organic matter decrement. The conversion ratios and composting rates obtained in this study using passive aeration with vertical pipes were well aligned with those found using forced air delivery systems. PMID:17121117

  4. Structural Stability of Human Fibroblast Growth Factor-1 Is Essential for Protective Effects Against Radiation-Induced Intestinal Damage

    SciTech Connect

    Nakayama, Fumiaki; Umeda, Sachiko; Yasuda, Takeshi; Asada, Masahiro; Motomura, Kaori; Suzuki, Masashi; Zakrzewska, Malgorzata; Imamura, Toru; Imai, Takashi

    2013-02-01

    Purpose: Human fibroblast growth factor-1 (FGF1) has radioprotective effects on the intestine, although its structural instability limits its potential for practical use. Several stable FGF1 mutants were created increasing stability in the order, wild-type FGF1, single mutants (Q40P, S47I, and H93G), Q40P/S47I, and Q40P/S47I/H93G. This study evaluated the contribution of the structural stability of FGF1 to its radioprotective effect. Methods and Materials: Each FGF1 mutant was administered intraperitoneally to BALB/c mice in the absence of heparin 24 h before or after total body irradiation (TBI) with {gamma}-rays at 8-12 Gy. Several radioprotective effects were examined in the jejunum. Results: Q40P/S47I/H93G could activate all subtypes of FGF receptors in vitro much more strongly than the wild-type without endogenous or exogenous heparin. Preirradiation treatment with Q40P/S47I/H93G significantly increased crypt survival more than wild-type FGF1 after TBI at 10 or 12 Gy, and postirradiation treatment with Q40P/S47I/H93G was effective in promoting crypt survival after TBI at 10, 11, or 12 Gy. In addition, crypt cell proliferation, crypt depth, and epithelial differentiation were significantly promoted by postirradiation treatment with Q40P/S47I/H93G. The level of stability of FGF1 mutants correlated with their mitogenic activities in vitro in the absence of heparin; however, preirradiation treatment with the mutants increased the crypt number to almost the same level as Q40P/S47I/H93G. When given 24 h after TBI at 10 Gy, all FGF1 mutants increased crypt survival more than wild-type FGF1, and Q40P/S47I/H93G had the strongest mitogenic effects in intestinal epithelial cells after radiation damage. Moreover, Q40P/S47I/H93G prolonged mouse survival after TBI because of the repair of intestinal damage. Conclusion: These findings suggest that the structural stability of FGF1 can contribute to the enhancement of protective effects against radiation-induced intestinal

  5. Fabrication, stability and efficacy of dual-component antimicrobial nanoemulsions: essential oil (thyme oil) and cationic surfactant (lauric arginate).

    PubMed

    Chang, Yuhua; McLandsborough, Lynne; McClements, David Julian

    2015-04-01

    The influence of a cationic surfactant (lauric arginate, LAE) on the physical properties and antimicrobial efficacy of thyme oil nanoemulsions was investigated. Nanoemulsions prepared from pure thyme oil were highly unstable due to Ostwald ripening, but they could be stabilized by adding a ripening inhibitor (corn oil) to the oil phase prior to homogenisation. The loading capacity and antimicrobial efficacy of thyme oil nanoemulsions were significantly increased by adding LAE. In the absence of LAE, at least 60 wt% corn oil had to be added to the lipid phase to inhibit Ostwald ripening; but in the presence of 0.1 wt% LAE, only 30 wt% corn oil was needed. LAE addition substantially increased the antimicrobial efficacy of the thyme oil nanoemulsions: 200 μg/ml thyme oil was needed to inhibit growth of a spoilage yeast (Zygosaccharomyces bailii) if LAE was added, whereas ⩾ 400 μg/ml was needed in the absence of LAE.

  6. Effect of thyme/cumin essential oils and butylated hydroxyl anisole/butylated hydroxyl toluene on physicochemical properties and oxidative/microbial stability of chicken patties.

    PubMed

    Sariçoban, Cemalettin; Yilmaz, Mustafa Tahsin

    2014-02-01

    In this study, effects of thyme/cumin essential oils (EO) and butylated hydroxyl anisole (BHA)/butylated hydroxyl toluene (BHT) on physicochemical properties and storage stability of chicken patties were compared in different storage periods (0, 3, 7, 14, 21, and 28 d). It was found that there were significant (P < 0.05) differences between physicochemical properties of patty samples treated with EO and the synthetic antioxidants. The EO showed similar performance to those of BHA and BHT in limiting TBARS values of chicken patty samples. Similarity in performance was also the case for microbial stability (total aerobic mesophilic, psychrotrophic, lactic acid, and coliform bacteria as well as molds and yeasts); namely, their effects were significant (P < 0.05). Effect of thyme EO was significant (P < 0.05) and remarkable, not allowing any coliform bacteria to grow in the samples. Given that EO were obtained from natural sources, the data suggested that the EO might be more useful than their synthetic counterparts, BHA and BHT, as additives for chicken patties to maintain oxidative/microbial stability and increase shelf life.

  7. ESSENTIAL ROLE OF SURFACE HYDROXYLS FOR THE STABILIZATION AND CATALYTIC ACTIVITY OF TiO2-SUPPORTED GOLD NANOPARTICLES

    SciTech Connect

    Veith, Gabriel M; Lupini, Andrew R; Dudney, Nancy J

    2009-01-01

    We report the investigation of titania supported gold catalysts prepared by magnetron sputtering. Catalysts grown on natural fumed titania were structurally unstable resulting in the rapid coarsening of 2.3 nm gold clusters into large ~20 nm gold clusters in a few days at room temperature under normal atmospheric conditions. However, treating the titania support powder to a mock-deposition-precipitation process, at pH 4 or pH 10, followed by the subsequent deposition of gold onto this treated powder produced a remarkable enhancement in gold particle stability and a 20-40 fold enhancement of catalytic activity respectively. This enhancement can not be attributed to the formation of oxygen vacancies on the TiO2 surface. Instead, it appears to be associated with the formation of strongly bound hydroxyl species on the TiO2 surface. The formation of surface hydroxyls during the deposition-precipitation method is coincidental and contributes significantly to the properties of Au/TiO2 catalysts.

  8. A nuclear-encoded protein of prokaryotic origin is essential for the stability of photosystem II in Arabidopsis thaliana.

    PubMed Central

    Meurer, J; Plücken, H; Kowallik, K V; Westhoff, P

    1998-01-01

    To understand the regulatory mechanisms underlying the biogenesis of photosystem II (PSII) we have characterized the nuclear mutant hcf136 of Arabidopsis thaliana and isolated the affected gene. The mutant is devoid of any photosystem II activity, and none of the nuclear- and plastome-encoded subunits of this photosystem accumulate to significant levels. Protein labelling studies in the presence of cycloheximide showed that the plastome-encoded PSII subunits are synthesized but are not stable. The HCF136 gene was isolated by virtue of its T-DNA tag, and its identity was confirmed by complementation of homozygous hcf136 seedlings. Immunoblot analysis of fractionated chloroplasts showed that the HCF136 protein is a lumenal protein, found only in stromal thylakoid lamellae. The HCF136 protein is produced already in dark-grown seedlings and its levels do not increase dramatically during light-induced greening. This accumulation profile confirms the mutational data by showing that the HCF136 protein must be present when PSII complexes are made. HCF136 homologues are found in the cyanobacterium Synechocystis species PCC6803 (slr2034) and the cyanelle genome of Cyanophora paradoxa (ORF333), but are lacking in the plastomes of chlorophytes and metaphytes as well as from those of rhodo- and chromophytes. We conclude that HCF136 encodes a stability and/or assembly factor of PSII which dates back to the cyanobacterial-like endosymbiont that led to the plastids of the present photosynthetic eukaryotes. PMID:9736608

  9. Purification and characterization of WaaP from Escherichia coli, a lipopolysaccharide kinase essential for outer membrane stability.

    PubMed

    Yethon, J A; Whitfield, C

    2001-02-23

    In Escherichia coli, Salmonella enterica, and Pseudomonas aeruginosa, the waaP (rfaP) gene product is required for the addition of phosphate to O-4 of the first heptose residue of the lipopolysaccharide (LPS) inner core region. This phosphate substitution is particularly important to the biology of these bacteria; it has previously been shown that WaaP is necessary for resistance to hydrophobic and polycationic antimicrobials in E. coli and that it is required for virulence in invasive strains of S. enterica. WaaP function is also known to be essential for the viability of P. aeruginosa. The predicted WaaP protein shows low levels of similarity (10-15% identity) to eukaryotic protein kinases, but its kinase activity has never been tested. Here we report the purification of WaaP and the reconstitution of its enzymatic activity in vitro. The purified enzyme catalyzes the incorporation of 33P from [gamma-33P]ATP into acceptor LPS purified from a defined E. coli waaP mutant. Enzymatic activity is dependent upon the presence of Mg2+ and is maximal from pH 8.0 to 9.0. The apparent Km (determined at saturating concentrations of the second substrate) is 0.13 mm for ATP and 76 microm for LPS. These data are the first proof that WaaP is indeed an LPS kinase. Further, site-directed mutagenesis of a predicted catalytic residue suggests that WaaP shares a common mechanism of action with eukaryotic protein kinases.

  10. Increase in activity of essential oil components carvacrol and thymol against Escherichia coli O157:H7 by addition of food stabilizers.

    PubMed

    Burt, Sara A; Vlielander, René; Haagsman, Henk P; Veldhuizen, Edwin J A

    2005-05-01

    The major components of oregano and thyme essential oils that had previously been shown to inhibit Escherichia coli O157:H7 were determined by high-performance liquid chromatography with UV detection and liquid chromatographic tandem mass spectrometry. The MICs and MBCs of carvacrol, thymol, p-cymene, and gamma-terpinene against a strain of E. coli O157: H7 phage type 34 isolated from bovine feces were determined by microdilution assay. The constituents were then tested in checkerboard assays to detect possible interactions. Carvacrol and thymol displayed bacteriostatic and bactericidal properties with MICs of 1.2 mmol/liter and were additive in combination. p-Cymene and gamma-terpinene displayed no measurable antibacterial activity up to 50 mmol/liter, and neither influenced the activity of carvacrol or thymol. Growth curves in the presence of nonlethal concentrations of carvacrol with the addition of agar (0.05%, wt/vol) or carrageenan (0.125%, wt/vol) as stabilizer were produced by optical density measurement. The stabilizers agar and carrageenan both significantly improved the effectiveness of carvacrol in broth, possibly because of a delay in the separation of the hydrophobic substrate from the aqueous phase of the medium. When carvacrol was dissolved in ethanol before addition to broth, stabilizers were not needed. Carvacrol and thymol, particularly when used in combination with a stabilizer or in an ethanol solution, may be effective in reducing the number or preventing growth of E. coli O157:H7 in liquid foods. PMID:15895722

  11. Anti-rancidity effect of essential oils, application in the lipid stability of cooked turkey meat patties and potential implications for health.

    PubMed

    Loizzo, Monica R; Tundis, Rosa; Menichini, Francesco; Duthie, Garry

    2015-02-01

    Twenty-three commercial essential oils were tested for their anti-rancidity effect and potential implications to prolong the induction time of corn oil and extend the shelf life of cooked turkey patties. Moreover, the potential health benefit was investigated through DPPH, ABTS, β-carotene bleaching, FRAP, and α-amylase inhibitory assays. Essential oils' composition was investigated by GC-MS. Cumin, thyme, clove, and cinnamon oils improved oxidative stability and increased the induction time of the corn oil 1.5-3 fold. Clove and cinnamon oils were particularly effective in delaying lipid oxidation of cooked turkey patties (time of induction 11.04 and 9.43 h) compared with the plain burger (5.04 h). Both oils are also characterized by a potent radical scavenging activity in ABTS test (IC(50) values of 1.43 and 2.05 μg/ml for cinnamon and clove, respectively). In the α-amylase inhibitory assay, cumin and grape fruits were the most potent with IC(50) values of 21.88 and 23.95 μg/ml, respectively.

  12. Anti-rancidity effect of essential oils, application in the lipid stability of cooked turkey meat patties and potential implications for health.

    PubMed

    Loizzo, Monica R; Tundis, Rosa; Menichini, Francesco; Duthie, Garry

    2015-02-01

    Twenty-three commercial essential oils were tested for their anti-rancidity effect and potential implications to prolong the induction time of corn oil and extend the shelf life of cooked turkey patties. Moreover, the potential health benefit was investigated through DPPH, ABTS, β-carotene bleaching, FRAP, and α-amylase inhibitory assays. Essential oils' composition was investigated by GC-MS. Cumin, thyme, clove, and cinnamon oils improved oxidative stability and increased the induction time of the corn oil 1.5-3 fold. Clove and cinnamon oils were particularly effective in delaying lipid oxidation of cooked turkey patties (time of induction 11.04 and 9.43 h) compared with the plain burger (5.04 h). Both oils are also characterized by a potent radical scavenging activity in ABTS test (IC(50) values of 1.43 and 2.05 μg/ml for cinnamon and clove, respectively). In the α-amylase inhibitory assay, cumin and grape fruits were the most potent with IC(50) values of 21.88 and 23.95 μg/ml, respectively. PMID:25265207

  13. Stabilization of Ultraviolet (UV)-stimulated Scaffold Protein A by Interaction with Ubiquitin-specific Peptidase 7 Is Essential for Transcription-coupled Nucleotide Excision Repair.

    PubMed

    Higa, Mitsuru; Zhang, Xue; Tanaka, Kiyoji; Saijo, Masafumi

    2016-06-24

    UV-sensitive syndrome is an autosomal recessive disorder characterized by hypersensitivity to UV light and deficiency in transcription-coupled nucleotide excision repair (TC-NER), a subpathway of nucleotide excision repair that rapidly removes transcription-blocking DNA damage. UV-sensitive syndrome consists of three genetic complementation groups caused by mutations in the CSA, CSB, and UVSSA genes. UV-stimulated scaffold protein A (UVSSA), the product of UVSSA, which is required for stabilization of Cockayne syndrome group B (CSB) protein and reappearance of the hypophosphorylated form of RNA polymerase II after UV irradiation, forms a complex with ubiquitin-specific peptidase 7 (USP7). In this study, we demonstrated that the deubiquitination activity of USP7 is suppressed by its interaction with UVSSA. The interaction required the tumor necrosis factor receptor-associated factor domain of USP7 and the central region of UVSSA and was disrupted by an amino acid substitution in the tumor necrosis factor receptor-associated factor-binding motif of UVSSA. Cells expressing mutant UVSSA were highly sensitive to UV irradiation and defective in recovery of RNA synthesis after UV irradiation. These results indicate that the interaction between UVSSA and USP7 is important for TC-NER. Furthermore, the mutant UVSSA was rapidly degraded by the proteasome, and CSB was also degraded after UV irradiation as observed in UVSSA-deficient cells. Thus, stabilization of UVSSA by interaction with USP7 is essential for TC-NER. PMID:27129218

  14. Renewal of radiological equipment.

    PubMed

    2014-10-01

    In this century, medical imaging is at the heart of medical practice. Besides providing fast and accurate diagnosis, advances in radiology equipment offer new and previously non-existing options for treatment guidance with quite low morbidity, resulting in the improvement of health outcomes and quality of life for the patients. Although rapid technological development created new medical imaging modalities and methods, the same progress speed resulted in accelerated technical and functional obsolescence of the same medical imaging equipment, consequently creating a need for renewal. Older equipment has a high risk of failures and breakdowns, which might cause delays in diagnosis and treatment of the patient, and safety problems both for the patient and the medical staff. The European Society of Radiology is promoting the use of up-to-date equipment, especially in the context of the EuroSafe Imaging Campaign, as the use of up-to-date equipment will improve quality and safety in medical imaging. Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or renewal. This plan should look forward a minimum of 5 years, with annual updates. Teaching points • Radiological equipment has a definite life cycle span, resulting in unavoidable breakdown and decrease or loss of image quality which renders equipment useless after a certain time period.• Equipment older than 10 years is no longer state-of-the art equipment and replacement is essential. Operating costs of older equipment will be high when compared with new equipment, and sometimes maintenance will be impossible if no spare parts are available.• Older equipment has a high risk of failure and breakdown, causing delays in diagnosis and treatment of the patient and safety problems both for the patient and the medical staff.• Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or replacement. This plan should look forward a

  15. Renewal of radiological equipment.

    PubMed

    2014-10-01

    In this century, medical imaging is at the heart of medical practice. Besides providing fast and accurate diagnosis, advances in radiology equipment offer new and previously non-existing options for treatment guidance with quite low morbidity, resulting in the improvement of health outcomes and quality of life for the patients. Although rapid technological development created new medical imaging modalities and methods, the same progress speed resulted in accelerated technical and functional obsolescence of the same medical imaging equipment, consequently creating a need for renewal. Older equipment has a high risk of failures and breakdowns, which might cause delays in diagnosis and treatment of the patient, and safety problems both for the patient and the medical staff. The European Society of Radiology is promoting the use of up-to-date equipment, especially in the context of the EuroSafe Imaging Campaign, as the use of up-to-date equipment will improve quality and safety in medical imaging. Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or renewal. This plan should look forward a minimum of 5 years, with annual updates. Teaching points • Radiological equipment has a definite life cycle span, resulting in unavoidable breakdown and decrease or loss of image quality which renders equipment useless after a certain time period.• Equipment older than 10 years is no longer state-of-the art equipment and replacement is essential. Operating costs of older equipment will be high when compared with new equipment, and sometimes maintenance will be impossible if no spare parts are available.• Older equipment has a high risk of failure and breakdown, causing delays in diagnosis and treatment of the patient and safety problems both for the patient and the medical staff.• Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or replacement. This plan should look forward a

  16. iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.

    PubMed

    Luo, Wei-Wei; Li, Shu; Li, Chen; Lian, Huan; Yang, Qing; Zhong, Bo; Shu, Hong-Bing

    2016-09-01

    STING is a central adaptor in the innate immune response to DNA viruses. However, the manner in which STING activity is regulated remains unclear. We identified iRhom2 ('inactive rhomboid protein 2') as a positive regulator of DNA-virus-triggered induction of type I interferons. iRhom2 deficiency markedly impaired DNA-virus- and intracellular-DNA-induced signaling in cells, and iRhom2-deficient mice were more susceptible to lethal herpes simplex virus type 1 (HSV-1) infection. iRhom2 was constitutively associated with STING and acted in two distinct processes to regulate STING activity. iRhom2 recruited the translocon-associated protein TRAPβ to the STING complex to facilitate trafficking of STING from the endoplasmic reticulum to perinuclear microsomes. iRhom2 also recruited the deubiquitination enzyme EIF3S5 to maintain the stability of STING through removal of its K48-linked polyubiquitin chains. These results suggest that iRhom2 is essential for STING activity, as it regulates TRAPβ-mediated translocation and EIF3S5-mediated deubiquitination of STING. PMID:27428826

  17. 21 CFR 225.30 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Equipment § 225.30 Equipment. (a) Equipment which is designed to perform its intended function and is properly installed and used is essential to the manufacture of medicated feeds. Such equipment permits production of feeds of uniform quality, facilitates cleaning, and minimizes spillage of drug components...

  18. Solar Equipment

    NASA Technical Reports Server (NTRS)

    1983-01-01

    A medical refrigeration and a water pump both powered by solar cells that convert sunlight directly into electricity are among the line of solar powered equipment manufactured by IUS (Independent Utility Systems) for use in areas where conventional power is not available. IUS benefited from NASA technology incorporated in the solar panel design and from assistance provided by Kerr Industrial Applications Center.

  19. Telescope Equipment

    NASA Technical Reports Server (NTRS)

    1988-01-01

    Renaissance Telescope for high resolution and visual astronomy has five 82-degree Field Tele-Vue Nagler Eyepieces, some of the accessories that contribute to high image quality. Telescopes and eyepieces are representative of a family of optical equipment manufactured by Tele-Vue Optics, Inc.

  20. mTORC2-PKBα/Akt1 Serine 473 phosphorylation axis is essential for regulation of FOXP3 Stability by chemokine CCL3 in psoriasis.

    PubMed

    Chen, Ling; Wu, Jinjin; Pier, Eric; Zhao, Yun; Shen, Zhu

    2013-02-01

    The connection between infections and acute guttate psoriasis (AGP) outbreaks/chronic plaque psoriasis (CPP) exacerbation has been known for years. Impaired function of FOXP3+Tregs in psoriasis has been identified. However, the mechanisms behind these two observations have not been fully interpreted. In the present study, we provide evidence to support chemokine CCL3 as one of the vital links between infections and FOXP3 stability in the psoriatic microenvironment. We found that serum CCL3, strongly induced by microorganism infections including streptococcus, was closely correlated with FOXP3 levels in CD4+CD25+T cells of patients with psoriasis. CCL3 manipulated FOXP3 stability in a concentration-dependent bidirectional manner. High-concentration CCL3 decreased FOXP3 stability by promoting FOXP3's degradation through K48-linkage ubiquitination. This degradation was mainly dependent on upregulation of Serine 473 phosphorylation of the PKBα/Akt1 isoform, and almost independent of mTORC1 (mammalian target of rapamycin complex 1) activity. On the other hand, low-concentration CCL3 could enhance FOXP3 stability by the maintenance of the PKC pathway and the restriction of the PKB/Akt pathway. We further demonstrated that enhancing FOXP3 stability by low-concentration CCL3 attributed, at least partly, to the prevention of cytoplasmic Sin1, a vital component of mTORC2, nuclear translocation. Our results suggest vital roles for CCL3-mTORC2-isoform PKB/Akt1 S473 phosphorylation axis in FOXP3+Tregs and the development of psoriasis.

  1. An Empirical Determination of Tasks Essential to Successful Performance as an Agricultural-Industrial Equipment Mechanic. Determination of a Common Core of Basic Skills in Agribusiness and Natural Resources.

    ERIC Educational Resources Information Center

    Yoder, Edgar P.; McCracken, J. David

    To improve vocational educational programs in agriculture, occupational information on a common core of basic skills within the occupational area of the agricultural-industrial equipment mechanic is presented in the revised task inventory survey. The purpose of the occupational survey was to identify a common core of basic skills which are…

  2. A comparison of intraoral antimicrobial effects of stabilized stannous fluoride dentifrice, baking soda/peroxide dentifrice, conventional NaF dentifrice and essential oil mouthrinse.

    PubMed

    Bacca, L A; Leusch, M; Lanzalaco, A C; Macksood, D; Bouwsma, O J; Shaffer, J B; Howard-Nordan, K S; Knippenberg, S H; Kreutzjans, M K; Miller, J M; Poore, C L; Sunberg, R J; Vastola, K A; Becus, M; Bartizek, R D; Block, R P; Briner, W W; White, D J

    1997-01-01

    The intraoral antimicrobial activity of four commercial oral products-conventional NaF dentifrice (Crest), baking soda/peroxide/NaF dentifrice (Mentadent), essential oil mouthrinse (Listerine) and SnF2 dentifrice (Crest Plus Gum Care)-have been compared in three test regimens. Formulations were compared for their ability to suppress the regrowth and apical extension of dental plaque following toothbrushing during thirty hours of non-brushing where products were used as oral rinses (30-hour plaque regrowth model). Formulations were also compared for their ability to suppress the colony-forming units (cfu) of facultative anaerobic bacteria sampled from buccal gingival surfaces following use (Gingival Surface Microbial Index-GSMI model). Lastly, formulations were compared for effects in suppressing the glycolytic metabolic activity and regrowth activity of in vivo-treated dental plaques sampled at various periods following topical use and incubated under controlled ex vivo conditions (Plaque Glycolysis and Regrowth-PGRM model). In thirty-hour plaque regrowth testing, the rank ordered antimicrobial efficacy of formulations followed SnF2 > essential oils > NaF = water = baking soda/peroxide. In GSMI testing, all formulations were shown to suppress the cfu of facultative anaerobic bacteria relative to baseline, although SnF2 treatment was observed to reduce bacterial levels to a significantly greater degree than NaF dentifrice or baking soda/peroxide dentifrice up to two hours following brushing. In PGRM testing, the SnF2 dentifrice provided significant inhibition of bacterial metabolism and regrowth following topical application when compared with the NaF dentifrice as control. The baking soda/peroxide dentifrice provided no reduction in either bacterial metabolism or regrowth in PGRM. Previous studies had demonstrated modest effects for essential oil rinse in reducing PGRM plaque regrowth, with no effects for this treatment on plaque metabolism. Overall, these results

  3. A comparison of intraoral antimicrobial effects of stabilized stannous fluoride dentifrice, baking soda/peroxide dentifrice, conventional NaF dentifrice and essential oil mouthrinse.

    PubMed

    Bacca, L A; Leusch, M; Lanzalaco, A C; Macksood, D; Bouwsma, O J; Shaffer, J B; Howard-Nordan, K S; Knippenberg, S H; Kreutzjans, M K; Miller, J M; Poore, C L; Sunberg, R J; Vastola, K A; Becus, M; Bartizek, R D; Block, R P; Briner, W W; White, D J

    1997-01-01

    The intraoral antimicrobial activity of four commercial oral products-conventional NaF dentifrice (Crest), baking soda/peroxide/NaF dentifrice (Mentadent), essential oil mouthrinse (Listerine) and SnF2 dentifrice (Crest Plus Gum Care)-have been compared in three test regimens. Formulations were compared for their ability to suppress the regrowth and apical extension of dental plaque following toothbrushing during thirty hours of non-brushing where products were used as oral rinses (30-hour plaque regrowth model). Formulations were also compared for their ability to suppress the colony-forming units (cfu) of facultative anaerobic bacteria sampled from buccal gingival surfaces following use (Gingival Surface Microbial Index-GSMI model). Lastly, formulations were compared for effects in suppressing the glycolytic metabolic activity and regrowth activity of in vivo-treated dental plaques sampled at various periods following topical use and incubated under controlled ex vivo conditions (Plaque Glycolysis and Regrowth-PGRM model). In thirty-hour plaque regrowth testing, the rank ordered antimicrobial efficacy of formulations followed SnF2 > essential oils > NaF = water = baking soda/peroxide. In GSMI testing, all formulations were shown to suppress the cfu of facultative anaerobic bacteria relative to baseline, although SnF2 treatment was observed to reduce bacterial levels to a significantly greater degree than NaF dentifrice or baking soda/peroxide dentifrice up to two hours following brushing. In PGRM testing, the SnF2 dentifrice provided significant inhibition of bacterial metabolism and regrowth following topical application when compared with the NaF dentifrice as control. The baking soda/peroxide dentifrice provided no reduction in either bacterial metabolism or regrowth in PGRM. Previous studies had demonstrated modest effects for essential oil rinse in reducing PGRM plaque regrowth, with no effects for this treatment on plaque metabolism. Overall, these results

  4. Efficiency of vanilla, patchouli and ylang ylang essential oils stabilized by iron oxide@C14 nanostructures against bacterial adherence and biofilms formed by Staphylococcus aureus and Klebsiella pneumoniae clinical strains.

    PubMed

    Bilcu, Maxim; Grumezescu, Alexandru Mihai; Oprea, Alexandra Elena; Popescu, Roxana Cristina; Mogoșanu, George Dan; Hristu, Radu; Stanciu, George A; Mihailescu, Dan Florin; Lazar, Veronica; Bezirtzoglou, Eugenia; Chifiriuc, Mariana Carmen

    2014-01-01

    Biofilms formed by bacterial cells are associated with drastically enhanced resistance against most antimicrobial agents, contributing to the persistence and chronicization of the microbial infections and to therapy failure. The purpose of this study was to combine the unique properties of magnetic nanoparticles with the antimicrobial activity of three essential oils to obtain novel nanobiosystems that could be used as coatings for catheter pieces with an improved resistance to Staphylococcus aureus and Klebsiella pneumoniae clinical strains adherence and biofilm development. The essential oils of ylang ylang, patchouli and vanilla were stabilized by the interaction with iron oxide@C14 nanoparticles to be further used as coating agents for medical surfaces. Iron oxide@C14 was prepared by co-precipitation of Fe+2 and Fe+3 and myristic acid (C14) in basic medium. Vanilla essential oil loaded nanoparticles pelliculised on the catheter samples surface strongly inhibited both the initial adherence of S. aureus cells (quantified at 24 h) and the development of the mature biofilm quantified at 48 h. Patchouli and ylang-ylang essential oils inhibited mostly the initial adherence phase of S. aureus biofilm development. In the case of K. pneumoniae, all tested nanosystems exhibited similar efficiency, being active mostly against the adherence K. pneumoniae cells to the tested catheter specimens. The new nanobiosystems based on vanilla, patchouli and ylang-ylang essential oils could be of a great interest for the biomedical field, opening new directions for the design of film-coated surfaces with anti-adherence and anti-biofilm properties.

  5. Efficiency of vanilla, patchouli and ylang ylang essential oils stabilized by iron oxide@C14 nanostructures against bacterial adherence and biofilms formed by Staphylococcus aureus and Klebsiella pneumoniae clinical strains.

    PubMed

    Bilcu, Maxim; Grumezescu, Alexandru Mihai; Oprea, Alexandra Elena; Popescu, Roxana Cristina; Mogoșanu, George Dan; Hristu, Radu; Stanciu, George A; Mihailescu, Dan Florin; Lazar, Veronica; Bezirtzoglou, Eugenia; Chifiriuc, Mariana Carmen

    2014-01-01

    Biofilms formed by bacterial cells are associated with drastically enhanced resistance against most antimicrobial agents, contributing to the persistence and chronicization of the microbial infections and to therapy failure. The purpose of this study was to combine the unique properties of magnetic nanoparticles with the antimicrobial activity of three essential oils to obtain novel nanobiosystems that could be used as coatings for catheter pieces with an improved resistance to Staphylococcus aureus and Klebsiella pneumoniae clinical strains adherence and biofilm development. The essential oils of ylang ylang, patchouli and vanilla were stabilized by the interaction with iron oxide@C14 nanoparticles to be further used as coating agents for medical surfaces. Iron oxide@C14 was prepared by co-precipitation of Fe+2 and Fe+3 and myristic acid (C14) in basic medium. Vanilla essential oil loaded nanoparticles pelliculised on the catheter samples surface strongly inhibited both the initial adherence of S. aureus cells (quantified at 24 h) and the development of the mature biofilm quantified at 48 h. Patchouli and ylang-ylang essential oils inhibited mostly the initial adherence phase of S. aureus biofilm development. In the case of K. pneumoniae, all tested nanosystems exhibited similar efficiency, being active mostly against the adherence K. pneumoniae cells to the tested catheter specimens. The new nanobiosystems based on vanilla, patchouli and ylang-ylang essential oils could be of a great interest for the biomedical field, opening new directions for the design of film-coated surfaces with anti-adherence and anti-biofilm properties. PMID:25375335

  6. Histone acetyl transferase 1 is essential for mammalian development, genome stability, and the processing of newly synthesized histones H3 and H4.

    PubMed

    Nagarajan, Prabakaran; Ge, Zhongqi; Sirbu, Bianca; Doughty, Cheryl; Agudelo Garcia, Paula A; Schlederer, Michaela; Annunziato, Anthony T; Cortez, David; Kenner, Lukas; Parthun, Mark R

    2013-06-01

    Histone acetyltransferase 1 is an evolutionarily conserved type B histone acetyltransferase that is thought to be responsible for the diacetylation of newly synthesized histone H4 on lysines 5 and 12 during chromatin assembly. To understand the function of this enzyme in a complex organism, we have constructed a conditional mouse knockout model of Hat1. Murine Hat1 is essential for viability, as homozygous deletion of Hat1 results in neonatal lethality. The lungs of embryos and pups genetically deficient in Hat1 were much less mature upon histological evaluation. The neonatal lethality is due to severe defects in lung development that result in less aeration and respiratory distress. Many of the Hat1(-/-) neonates also display significant craniofacial defects with abnormalities in the bones of the skull and jaw. Hat1(-/-) mouse embryonic fibroblasts (MEFs) are defective in cell proliferation and are sensitive to DNA damaging agents. In addition, the Hat1(-/-) MEFs display a marked increase in genome instability. Analysis of histone dynamics at sites of replication-coupled chromatin assembly demonstrates that Hat1 is not only responsible for the acetylation of newly synthesized histone H4 but is also required to maintain the acetylation of histone H3 on lysines 9, 18, and 27 during replication-coupled chromatin assembly.

  7. FAP20 is an inner junction protein of doublet microtubules essential for both the planar asymmetrical waveform and stability of flagella in Chlamydomonas

    PubMed Central

    Yanagisawa, Haru-aki; Mathis, Garrison; Oda, Toshiyuki; Hirono, Masafumi; Richey, Elizabeth A.; Ishikawa, Hiroaki; Marshall, Wallace F.; Kikkawa, Masahide; Qin, Hongmin

    2014-01-01

    The axoneme—the conserved core of eukaryotic cilia and flagella—contains highly specialized doublet microtubules (DMTs). A long-standing question is what protein(s) compose the junctions between two tubules in DMT. Here we identify a highly conserved flagellar-associated protein (FAP), FAP20, as an inner junction (IJ) component. The flagella of Chlamydomonas FAP20 mutants have normal length but beat with an abnormal symmetrical three-dimensional pattern. In addition, the mutant axonemes are liable to disintegrate during beating, implying that interdoublet connections may be weakened. Conventional electron microscopy shows that the mutant axonemes lack the IJ, and cryo–electron tomography combined with a structural labeling method reveals that the labeled FAP20 localizes at the IJ. The mutant axonemes also lack doublet-specific beak structures, which are localized in the proximal portion of the axoneme and may be involved in planar asymmetric flagellar bending. FAP20 itself, however, may not be a beak component, because uniform localization of FAP20 along the entire length of all nine DMTs is inconsistent with the beak's localization. FAP20 is the first confirmed component of the IJ. Our data also suggest that the IJ is important for both stabilizing the axoneme and scaffolding intra–B-tubular substructures required for a planar asymmetrical waveform. PMID:24574454

  8. The BEACH Domain Protein SPIRRIG Is Essential for Arabidopsis Salt Stress Tolerance and Functions as a Regulator of Transcript Stabilization and Localization

    PubMed Central

    Steffens, Alexandra; Bräutigam, Andrea; Jakoby, Marc; Hülskamp, Martin

    2015-01-01

    Members of the highly conserved class of BEACH domain containing proteins (BDCPs) have been established as broad facilitators of protein–protein interactions and membrane dynamics in the context of human diseases like albinism, bleeding diathesis, impaired cellular immunity, cancer predisposition, and neurological dysfunctions. Also, the Arabidopsis thaliana BDCP SPIRRIG (SPI) is important for membrane integrity, as spi mutants exhibit split vacuoles. In this work, we report a novel molecular function of the BDCP SPI in ribonucleoprotein particle formation. We show that SPI interacts with the P-body core component DECAPPING PROTEIN 1 (DCP1), associates to mRNA processing bodies (P-bodies), and regulates their assembly upon salt stress. The finding that spi mutants exhibit salt hypersensitivity suggests that the local function of SPI at P-bodies is of biological relevance. Transcriptome-wide analysis revealed qualitative differences in the salt stress-regulated transcriptional response of Col-0 and spi. We show that SPI regulates the salt stress-dependent post-transcriptional stabilization, cytoplasmic agglomeration, and localization to P-bodies of a subset of salt stress-regulated mRNAs. Finally, we show that the PH-BEACH domains of SPI and its human homolog FAN (Factor Associated with Neutral sphingomyelinase activation) interact with DCP1 isoforms from plants, mammals, and yeast, suggesting the evolutionary conservation of an association of BDCPs and P-bodies. PMID:26133670

  9. FAP20 is an inner junction protein of doublet microtubules essential for both the planar asymmetrical waveform and stability of flagella in Chlamydomonas.

    PubMed

    Yanagisawa, Haru-aki; Mathis, Garrison; Oda, Toshiyuki; Hirono, Masafumi; Richey, Elizabeth A; Ishikawa, Hiroaki; Marshall, Wallace F; Kikkawa, Masahide; Qin, Hongmin

    2014-05-01

    The axoneme-the conserved core of eukaryotic cilia and flagella-contains highly specialized doublet microtubules (DMTs). A long-standing question is what protein(s) compose the junctions between two tubules in DMT. Here we identify a highly conserved flagellar-associated protein (FAP), FAP20, as an inner junction (IJ) component. The flagella of Chlamydomonas FAP20 mutants have normal length but beat with an abnormal symmetrical three-dimensional pattern. In addition, the mutant axonemes are liable to disintegrate during beating, implying that interdoublet connections may be weakened. Conventional electron microscopy shows that the mutant axonemes lack the IJ, and cryo-electron tomography combined with a structural labeling method reveals that the labeled FAP20 localizes at the IJ. The mutant axonemes also lack doublet-specific beak structures, which are localized in the proximal portion of the axoneme and may be involved in planar asymmetric flagellar bending. FAP20 itself, however, may not be a beak component, because uniform localization of FAP20 along the entire length of all nine DMTs is inconsistent with the beak's localization. FAP20 is the first confirmed component of the IJ. Our data also suggest that the IJ is important for both stabilizing the axoneme and scaffolding intra-B-tubular substructures required for a planar asymmetrical waveform.

  10. The BEACH Domain Protein SPIRRIG Is Essential for Arabidopsis Salt Stress Tolerance and Functions as a Regulator of Transcript Stabilization and Localization.

    PubMed

    Steffens, Alexandra; Bräutigam, Andrea; Jakoby, Marc; Hülskamp, Martin

    2015-07-01

    Members of the highly conserved class of BEACH domain containing proteins (BDCPs) have been established as broad facilitators of protein-protein interactions and membrane dynamics in the context of human diseases like albinism, bleeding diathesis, impaired cellular immunity, cancer predisposition, and neurological dysfunctions. Also, the Arabidopsis thaliana BDCP SPIRRIG (SPI) is important for membrane integrity, as spi mutants exhibit split vacuoles. In this work, we report a novel molecular function of the BDCP SPI in ribonucleoprotein particle formation. We show that SPI interacts with the P-body core component DECAPPING PROTEIN 1 (DCP1), associates to mRNA processing bodies (P-bodies), and regulates their assembly upon salt stress. The finding that spi mutants exhibit salt hypersensitivity suggests that the local function of SPI at P-bodies is of biological relevance. Transcriptome-wide analysis revealed qualitative differences in the salt stress-regulated transcriptional response of Col-0 and spi. We show that SPI regulates the salt stress-dependent post-transcriptional stabilization, cytoplasmic agglomeration, and localization to P-bodies of a subset of salt stress-regulated mRNAs. Finally, we show that the PH-BEACH domains of SPI and its human homolog FAN (Factor Associated with Neutral sphingomyelinase activation) interact with DCP1 isoforms from plants, mammals, and yeast, suggesting the evolutionary conservation of an association of BDCPs and P-bodies. PMID:26133670

  11. An Essential Role of INI1/hSNF5 Chromatin Remodeling Protein in HIV-1 Posttranscriptional Events and Gag/Gag-Pol Stability

    PubMed Central

    La Porte, Annalena; Cano, Jennifer; Wu, Xuhong; Mitra, Doyel

    2016-01-01

    ABSTRACT INI1/hSNF5/SMARCB1/BAF47 is an HIV-specific integrase (IN)-binding protein that influences HIV-1 transcription and particle production. INI1 binds to SAP18 (Sin3a-associated protein, 18 kDa), and both INI1 and SAP18 are incorporated into HIV-1 virions. To determine the significance of INI1 and the INI1-SAP18 interaction during HIV-1 replication, we isolated a panel of SAP18-interaction-defective (SID)-INI1 mutants using a yeast reverse two-hybrid screen. The SID-INI1 mutants, which retained the ability to bind to IN, cMYC, and INI1 but were impaired for binding to SAP18, were tested for their effects on HIV-1 particle production. SID-INI1 dramatically reduced the intracellular Gag/Gag-Pol protein levels and, in addition, decreased viral particle production. The SID-INI1-mediated effects were less dramatic in trans complementation assays using IN deletion mutant viruses with Vpr-reverse transcriptase (RT)-IN. SID-INI1 did not inhibit long-terminal-repeat (LTR)-mediated transcription, but it marginally decreased the steady-state gag RNA levels, suggesting a posttranscriptional effect. Pulse-chase analysis indicated that in SID-INI1-expressing cells, the pr55Gag levels decreased rapidly. RNA interference analysis indicated that small hairpin RNA (shRNA)-mediated knockdown of INI1 reduced the intracellular Gag/Gag-Pol levels and further inhibited HIV-1 particle production. These results suggest that SID-INI1 mutants inhibit multiple stages of posttranscriptional events of HIV-1 replication, including intracellular Gag/Gag-Pol RNA and protein levels, which in turn inhibits assembly and particle production. Interfering INI1 leads to a decrease in particle production and Gag/Gag-Pol protein levels. Understanding the role of INI1 and SAP18 in HIV-1 replication is likely to provide novel insight into the stability of Gag/Gag-Pol, which may lead to the development of novel therapeutic strategies to inhibit HIV-1 late events. IMPORTANCE Significant gaps exist in our

  12. 14 CFR 25.1431 - Electronic equipment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... that it does not cause essential loads to become inoperative as a result of electrical power supply... electronic equipment must be supplied with power under the requirements of § 25.1355(c). (c) Radio...

  13. 14 CFR 25.1431 - Electronic equipment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... that it does not cause essential loads to become inoperative as a result of electrical power supply... electronic equipment must be supplied with power under the requirements of § 25.1355(c). (c) Radio...

  14. 14 CFR 25.1431 - Electronic equipment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... that it does not cause essential loads to become inoperative as a result of electrical power supply... electronic equipment must be supplied with power under the requirements of § 25.1355(c). (c) Radio...

  15. Aquatic Equipment Information.

    ERIC Educational Resources Information Center

    Sova, Ruth

    Equipment usually used in water exercise programs is designed for variety, intensity, and program necessity. This guide discusses aquatic equipment under the following headings: (1) equipment design; (2) equipment principles; (3) precautions and contraindications; (4) population contraindications; and (5) choosing equipment. Equipment is used…

  16. The RNA Binding Protein Tudor-SN Is Essential for Stress Tolerance and Stabilizes Levels of Stress-Responsive mRNAs Encoding Secreted Proteins in Arabidopsis[C][W][OA

    PubMed Central

    dit Frey, Nicolas Frei; Muller, Philippe; Jammes, Fabien; Kizis, Dimosthenis; Leung, Jeffrey; Perrot-Rechenmann, Catherine; Bianchi, Michele Wolfe

    2010-01-01

    Tudor-SN (TSN) copurifies with the RNA-induced silencing complex in animal cells where, among other functions, it is thought to act on mRNA stability via the degradation of specific dsRNA templates. In plants, TSN has been identified biochemically as a cytoskeleton-associated RNA binding activity. In eukaryotes, it has recently been identified as a conserved primary target of programmed cell death–associated proteolysis. We have investigated the physiological role of TSN by isolating null mutations for two homologous genes in Arabidopsis thaliana. The double mutant tsn1 tsn2 displays only mild growth phenotypes under nonstress conditions, but germination, growth, and survival are severely affected under high salinity stress. Either TSN1 or TSN2 alone can complement the double mutant, indicating their functional redundancy. TSN accumulates heterogeneously in the cytosol and relocates transiently to a diffuse pattern in response to salt stress. Unexpectedly, stress-regulated mRNAs encoding secreted proteins are significantly enriched among the transcripts that are underrepresented in tsn1 tsn2. Our data also reveal that TSN is important for RNA stability of its targets. These findings show that TSN is essential for stress tolerance in plants and implicate TSN in new, potentially conserved mechanisms acting on mRNAs entering the secretory pathway. PMID:20484005

  17. Stability of a Ag/AgCl reference electrode equipped with an ionic liquid salt bridge composed of 1-methyl-3-octylimidazolium bis(trifluoromethanesulfonyl)-amide in potentiometry of pH standard buffers.

    PubMed

    Shibata, Manabu; Yamanuki, Mikito; Iwamoto, Yasukazu; Nomura, Satoshi; Kakiuchi, Takashi

    2010-01-01

    The stability of a Ag/AgCl reference electrode equipped with a gelled ionic liquid, 1-methyl-3-octylimidazolium bis(trifluoromethanesulfonyl)amide (C(8)mimC(1)C(1)N), as a salt bridge, was examined in the potentiometry of pH standard solutions. The variation in the liquid junction potential (LJP) of the ionic liquid (IL)-type reference electrode, measured with respect to a double junction-type KCl reference electrode, was within 1 mV when one standard solution was replaced by another, except for the phthalate standard. The time course of the potential of the IL-type reference electrode showed a standard deviation of ±0.3 mV in all buffer solutions. The reproducible deviation of the potential of the IL-type reference electrode in the phthalate pH standard amounted to 5 mV. The deviation is due to the partition of the hydrogen phthalate in the C(8)mimC(1)C(1)N, influencing the phase boundary potential (PBP) across the interface between C(8)mimC(1)C(1)N and the phthalate standard. If a citrate standard is used instead of the phthalate buffer, the IL salt bridge works satisfactorily as a salt bridge for a reference electrode suitable for potentiometoric pH measurements.

  18. Essential thrombocythemia

    PubMed Central

    Brière, Jean B

    2007-01-01

    Essential thrombocythemia (ET) is an acquired myeloproliferative disorder (MPD) characterized by a sustained elevation of platelet number with a tendency for thrombosis and hemorrhage. The prevalence in the general population is approximately 30/100,000. The median age at diagnosis is 65 to 70 years, but the disease may occur at any age. The female to male ratio is about 2:1. The clinical picture is dominated by a predisposition to vascular occlusive events (involving the cerebrovascular, coronary and peripheral circulation) and hemorrhages. Some patients with ET are asymptomatic, others may experience vasomotor (headaches, visual disturbances, lightheadedness, atypical chest pain, distal paresthesias, erythromelalgia), thrombotic, or hemorrhagic disturbances. Arterial and venous thromboses, as well as platelet-mediated transient occlusions of the microcirculation and bleeding, represent the main risks for ET patients. Thromboses of large arteries represent a major cause of mortality associated with ET or can induce severe neurological, cardiac or peripheral artery manifestations. Acute leukemia or myelodysplasia represent only rare and frequently later-onset events. The molecular pathogenesis of ET, which leads to the overproduction of mature blood cells, is similar to that found in other clonal MPDs such as chronic myeloid leukemia, polycythemia vera and myelofibrosis with myeloid metaplasia of the spleen. Polycythemia vera, myelofibrosis with myeloid metaplasia of the spleen and ET are generally associated under the common denomination of Philadelphia (Ph)-negative MPDs. Despite the recent identification of the JAK2 V617F mutation in a subset of patients with Ph-negative MPDs, the detailed pathogenetic mechanism is still a matter of discussion. Therapeutic interventions in ET are limited to decisions concerning the introduction of anti-aggregation therapy and/or starting platelet cytoreduction. The therapeutic value of hydroxycarbamide and aspirin in high risk

  19. 47 CFR 18.211 - Multiple listing of equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... same or essentially the same equipment will be marketed under more than one FCC Identifier, equipment authorization must be requested on an FCC Form 731 for each FCC Identifier. (b) If equipment authorization for additional FCC Identifiers is requested in the initial application, a statement shall be included...

  20. Schools Lack the Equipment to Carry out Essential Practical Science

    ERIC Educational Resources Information Center

    Education in Science, 2013

    2013-01-01

    SCORE is a collaboration of organisations that aim to improve science education in UK schools and colleges by supporting the development and implementation of effective education policy. Research commissioned by SCORE (Science Community Representing Education), a collaboration including the Association for Science Education (ASE), reports that…

  1. Gene expression of heat shock protein 70 and antioxidant enzymes, oxidative status, and meat oxidative stability of cyclically heat-challenged finishing broilers fed Origanum compactum and Curcuma xanthorrhiza essential oils.

    PubMed

    Akbarian, A; Michiels, J; Golian, A; Buyse, J; Wang, Y; De Smet, S

    2014-08-01

    Heat stress in poultry is a serious problem in many countries and has been associated with oxidative stress. Hence, nutritional interventions with antioxidants might be beneficial. Therefore, the effects of dietary Curcuma xanthorrhiza (CX) and Origanum compactum (OC) essential oils on mRNA levels of heat shock protein 70 and antioxidant enzymes, oxidative status, and meat oxidative stability of heat-challenged broilers were studied. Starting on d 25 of age, a control diet and 4 diets containing 200 or 400 mg/kg feed of CX or OC (CX200, CX400, OC200, OC400 diets) were fed to 3 pen replicates of 20 Ross 308 chickens each. From d 28 of age on, the temperature was increased from 22 to 34°C with 50% RH for 5 h daily during 2 wk. Dietary CX or OC did not affect zootechnical performance. Feeding CX400 and both levels of OC increased the a* value in stored breast meat (P < 0.05), and OC diets tended to decrease the thiobarbituric acid reactive substances values in fresh breast meat (P = 0.061). Compared with control, at d 31, feeding CX400 and OC400 reduced mRNA levels of heat shock protein 70 and increased mRNA levels of catalase in kidney and liver (P < 0.05). The mRNA levels of superoxide dismutase were increased at d 31 on the OC400 diet in kidney and on the CX400 diet in heart (P < 0.05). In heart, at d 31, both dietary levels of CX and OC200 resulted in higher glutathione peroxidase activity (P < 0.05). Feeding CX400 increased superoxide dismutase activity in liver, kidney, and heart at d 31 (P < 0.05). Catalase activity was increased in the CX200 and OC400 groups at d 42 (P < 0.05). Feeding CX at both levels and OC200 decreased plasma malondialdehyde concentrations at d 42 (P < 0.05). In conclusion, dietary essential oils rich in simple phenolic compounds offer potential for improving the antioxidant defense against heat stress-induced changes.

  2. [Antioxidant properties of essential oils].

    PubMed

    Misharina, T A; Terenina, M B; Krikunova, N I

    2009-01-01

    By the method of capillary gas-liquid chromatography we studied antioxidant properties and stability during the storage of hexane solutions of 14 individual essential oils from black and white pepper (Piper nigrum L.), cardamom (Elettaria cardamomum L.), nutmeg (Myristica fragrans Houtt.), mace (Myristica fragrans Houtt), juniperberry (Juniperus communis L.), seed of fennel (Foeniculum vulgare Mill., var. dulce Thelling), caraway (Carvum carvi L.), dry leaves of cinnamon (Cinnamomum zeylanicum Bl.), marjoram (Origanum majorana L.), laurel (Laurus nobilis L.), ginger (Zingiber officinale L.), garlic (Allium sativum L.), and clove bud (Caryophyllus aromaticus L.). We assessed the antioxidant properties by the oxidation of aliphatic aldehyde (trans-2-hexenal) into the according carbon acid. We established that essential oils of garlic, clove bud, ginger and leaves of cinnamon have the maximal efficiency of inhibition of hexenal oxidation (80-93%), while black pepper oil has the minimal (49%). Antioxidant properties of essential oils with a high content of substituted phenols depended poorly on its concentration in model systems. We studied the changes in essential oils content during the storage of its hexane solutions for 40 days in the light and out of the light and compared it with the stability of essential oils stored for a year out of the light. PMID:20067158

  3. [Antioxidant properties of essential oils].

    PubMed

    Misharina, T A; Terenina, M B; Krikunova, N I

    2009-01-01

    By the method of capillary gas-liquid chromatography we studied antioxidant properties and stability during the storage of hexane solutions of 14 individual essential oils from black and white pepper (Piper nigrum L.), cardamom (Elettaria cardamomum L.), nutmeg (Myristica fragrans Houtt.), mace (Myristica fragrans Houtt), juniperberry (Juniperus communis L.), seed of fennel (Foeniculum vulgare Mill., var. dulce Thelling), caraway (Carvum carvi L.), dry leaves of cinnamon (Cinnamomum zeylanicum Bl.), marjoram (Origanum majorana L.), laurel (Laurus nobilis L.), ginger (Zingiber officinale L.), garlic (Allium sativum L.), and clove bud (Caryophyllus aromaticus L.). We assessed the antioxidant properties by the oxidation of aliphatic aldehyde (trans-2-hexenal) into the according carbon acid. We established that essential oils of garlic, clove bud, ginger and leaves of cinnamon have the maximal efficiency of inhibition of hexenal oxidation (80-93%), while black pepper oil has the minimal (49%). Antioxidant properties of essential oils with a high content of substituted phenols depended poorly on its concentration in model systems. We studied the changes in essential oils content during the storage of its hexane solutions for 40 days in the light and out of the light and compared it with the stability of essential oils stored for a year out of the light.

  4. Water-Using Equipment: Commercial and Industrial

    SciTech Connect

    Solana, Amy E.; Mcmordie, Katherine

    2006-01-24

    Water is an important aspect of many facets in energy engineering. While the previous article detailed domestic related water-using equipment such as toilets and showerheads, this article focuses on various types of water-using equipment in commercial and industrial facilities, including commercial dishwashers and laundry, single-pass cooling equipment, boilers and steam generators, cooling towers, and landscape irrigation. Opportunities for water and energy conservation are explained, including both technology retrofits and operation and maintenance changes. Water management planning and leak detection are also included as they are essential to a successful water management program.

  5. Personal protective equipment

    MedlinePlus

    ... protective equipment. Available at: www.cdc.gov/niosh/ppe . Accessed October 27, 2015. Holland MG, Cawthon D. Personal protective equipment and decontamination of adults and children. Emerg Med Clin N ...

  6. Medical Issues: Equipment

    MedlinePlus

    ... Pool Living With SMA Medical Issues Palliative Breathing Orthopedics Nutrition Equipment Daily Life At School At Home ... Diagnosed Living With SMA Medical Issues Palliative Breathing Orthopedics Nutrition Equipment Daily Life Grief & Loss Community & Local ...

  7. Exercise Equipment: Neutral Buoyancy

    NASA Technical Reports Server (NTRS)

    Shackelford, Linda; Valle, Paul

    2016-01-01

    Load Bearing Equipment for Neutral Buoyancy (LBE-NB) is an exercise frame that holds two exercising subjects in position as they apply counter forces to each other for lower extremity and spine loading resistance exercises. Resistance exercise prevents bone loss on ISS, but the ISS equipment is too massive for use in exploration craft. Integrating the human into the load directing, load generating, and motion control functions of the exercise equipment generates safe exercise loads with less equipment mass and volume.

  8. Mobile Equipment Expands Inventory.

    ERIC Educational Resources Information Center

    McGough, Robert L.; And Others

    1978-01-01

    Describes the Mobile Equipment Modules (MEM) system in Duluth, Minnesota. MEM is a way to hold down costs and increase learning opportunities by consolidating purchases of expensive shop equipment within the school district, grouping the equipment in modules, and scheduling and moving it from school to school as needed. (MF)

  9. Essential Laboratory Activities Guide. Secondary Science.

    ERIC Educational Resources Information Center

    Duval County Schools, Jacksonville, FL.

    This teacher's guide was developed for use in junior and senior high schools in Duval County, Jacksonville, Florida, for the purpose of identifying those secondary science laboratory experiences which are essential to the development of science content knowledge and competency in handling science laboratory equipment and consumables. The guide…

  10. Drawing Evaluation Report for Sampling Equipment

    SciTech Connect

    BOGER, R.M.

    1999-09-09

    This document presents the results of a task to update the evaluation of River Protection Project (WP) sampling equipment drawings and updates the assigned drawings category as either essential, support, or general drawings. This report updates the drawing evaluation that was originally done per Engineering Task Plan For Truck 3 & 4 Drawing Compliance and Evaluation. The scope of this report is limited to updating the evaluation and identification of drawing category for drawings of certain tank waste sampling equipment for which the RPP Characterization Project has been assigned custody, including: vapor sampling, grab sampling, auger sampling, all core sampling equipment, and Light Duty Utility Arm (LDUA) (see LMHC contract No. 519, release 10). This report does not address drawings for other waste tank deployed equipment systems having similar assigned custody, such as, Cone Penetrometer system, or Long Length Contaminated Equipment (LLCE). The Cone Penetrometer system, which is depicted on vendor drawings, (not H- series), is not currently turned over to operations for deployment. The LLCE equipment was just recently assigned to Characterization Project and was not included in the original scope for this update and will be addressed in the evaluation update scheduled for later in fiscal year 1999, when equipment ownership is determined.

  11. AUDIOVISUAL EQUIPMENT STANDARDS.

    ERIC Educational Resources Information Center

    PATTERSON, PIERCE E.; AND OTHERS

    RECOMMENDED STANDARDS FOR AUDIOVISUAL EQUIPMENT WERE PRESENTED SEPARATELY FOR GRADES KINDERGARTEN THROUGH SIX, AND FOR JUNIOR AND SENIOR HIGH SCHOOLS. THE ELEMENTARY SCHOOL EQUIPMENT CONSIDERED WAS THE FOLLOWING--CLASSROOM LIGHT CONTROL, MOTION PICTURE PROJECTOR WITH MOBILE STAND AND SPARE REELS, COMBINATION 2 INCH X 2 INCH SLIDE AND FILMSTRIP…

  12. Shipboard Electronic Equipments.

    ERIC Educational Resources Information Center

    Naval Personnel Program Support Activity, Washington, DC.

    Fundamentals of major electronic equipments on board ships are presented in this text prepared for naval officers in general. Basic radio principles are discussed in connection with various types of transmitters, receivers, antennas, couplers, transfer panels, remote-control units, frequency standard equipments, teletypewriters, and facsimile…

  13. Technology Equipment Rooms.

    ERIC Educational Resources Information Center

    Day, C. William

    2001-01-01

    Examines telecommunications equipment room design features that allow for growth and can accommodate numerous equipment replacements and upgrades with minimal service disruption and with minimal cost. Considerations involving the central hub, power and lighting needs, air conditioning, and fire protection are discussed. (GR)

  14. Laboratory Equipment Criteria.

    ERIC Educational Resources Information Center

    State Univ. Construction Fund, Albany, NY.

    Requirements for planning, designing, constructing and installing laboratory furniture are given in conjunction with establishing facility criteria for housing laboratory equipment. Furniture and equipment described include--(1) center tables, (2) reagent racks, (3) laboratory benches and their mechanical fixtures, (4) sink and work counters, (5)…

  15. Equipment & New Products.

    ERIC Educational Resources Information Center

    Poitras, Adrian W., Ed.

    1977-01-01

    Presents several new products and equipment for teaching college science courses such as laser optics bench, portable digital thermometer, solar energy furnaces and blackboard optics kit. A description of all equipment or products, cost, and addresses of manufacturers are also included. (HM)

  16. Adaptive Recreational Equipment.

    ERIC Educational Resources Information Center

    Schilling, Mary Lou, Ed.

    1983-01-01

    Designed for teachers interested in therapeutic recreation, the document lists sources of adaptive recreational equipment and their homemade counterparts. Brief descriptions for ordering or constructing recreational equipment for the visually impaired, poorly coordinated, physically impaired, and mentally retarded are given. Specific adaptations…

  17. Equipment Operator 1 & C.

    ERIC Educational Resources Information Center

    Naval Education and Training Program Development Center, Pensacola, FL.

    The Rate Training Manual and Nonresident Career Course (RTM/NRCC) form a self-study package to assist Navy Equipment Operators First and Chief in fulfilling the requirements of their rating. (Navy Equipment Operators First and Chief direct and coordinate efforts of individuals and crews in construction, earthmoving, roadbuilding, quarrying, and…

  18. Troubleshooting rotating equipment

    SciTech Connect

    Wong, R.F. )

    1992-10-01

    This paper reports that equipment problems in a Peruvian refinery illustrate the process engineer's role as a troubleshooter. Examples show that rotating equipment problems can stem from mechanical or process factors and involve both inspection/maintenance specialists and process engineers.

  19. Heavy Equipment. Trade and Industrial Education Trade Preparatory Training Guide.

    ERIC Educational Resources Information Center

    Nebraska State Dept. of Education, Lincoln. Div. of Vocational Education.

    One of a series of curriculum guides prepared for the building occupations cluster of the construction/fabrication occupational group, this guide identifies the essentials of the heavy equipment trade as recommended by the successful heavy equipment operator. An instructional program based upon the implementation of the guide is expected to…

  20. 14 CFR 23.1309 - Equipment, systems, and installations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) Equipment essential to safe operation; or (ii) Other equipment unless there is a means to inform the pilot... result from a single failure; (2) Each hazardous failure condition is extremely remote; and (3) Each major failure condition is remote. (d) Information concerning an unsafe system operating condition...

  1. Guidebook to Constructing Inexpensive Science Teaching Equipment, Volume 1: Biology.

    ERIC Educational Resources Information Center

    Lockard, J. David

    This guidebook contains designs of laboratory equipment considered essential for student investigations in introductory biology in developing countries. The designs presented are based on the premise that many students and teachers will wish to make equipment for themselves. Although all the designs have been tested under laboratory conditions at…

  2. [Medical Equipment Maintenance Methods].

    PubMed

    Liu, Hongbin

    2015-09-01

    Due to the high technology and the complexity of medical equipment, as well as to the safety and effectiveness, it determines the high requirements of the medical equipment maintenance work. This paper introduces some basic methods of medical instrument maintenance, including fault tree analysis, node method and exclusive method which are the three important methods in the medical equipment maintenance, through using these three methods for the instruments that have circuit drawings, hardware breakdown maintenance can be done easily. And this paper introduces the processing methods of some special fault conditions, in order to reduce little detours in meeting the same problems. Learning is very important for stuff just engaged in this area.

  3. Leasing versus buying equipment.

    PubMed

    Grossman, R

    1983-01-01

    For the upgrading of equipment that is necessary in radiologic practice, leasing is more convenient and less expensive than buying. Changes in tax laws, embodied in the Economic Recovery Act of 1981, have increased tax benefits of this arrangement.

  4. Cleaning supplies and equipment

    MedlinePlus

    ... something means to clean it to destroy germs. Disinfectants are the cleaning solutions that are used to ... each solution. You may need to allow the disinfectant to dry on the equipment for a set ...

  5. Equipment & New Products.

    ERIC Educational Resources Information Center

    Poitras, Adrian W., Ed.

    1979-01-01

    Reviews new science equipment and products for the laboratory. Includes hand-held calculators, fiberglass fume hoods, motorized microtomy, disposable mouse cages, and electric timers. Describes 11 products total. Provides manufacturer name, address, and price. (MA)

  6. Selecting Library Furniture & Equipment.

    ERIC Educational Resources Information Center

    Media & Methods, 1997

    1997-01-01

    Offers suggestions for selecting school library furniture and equipment. Describes various models of computer workstations; reading tables and chairs; and shelving. Sidebar lists names and addresses of library furniture manufactures and distributors. (AEF)

  7. Wellhead equipment support

    SciTech Connect

    Nichols, R.P.

    1987-03-24

    A wellhead assembly is described for supporting equipment in a well, comprising: a suspension nut having a threaded outer surface; a wellhead member having an inner threaded surface adapted to mesh with the threaded outer surface of the suspension nut; the suspension nut having a projection extending axially from its threaded outer surface and having an inner surface adapted to support equipment in the well; at least a portion of the inner surface for supporting the equipment facing both inwardly and upwardly such that force exerted by the weight of the equipment against the inner surface is transformed at least in part to a radially outwardly directed force; the projecting having an outer surface sized such that the outer surface is spaced from an inner surface of the wellhead member in the absence of force exerted against the inner surface of the projection such that the projection is deflected outwardly by the force exerted by the weight of the equipment against the inner surface.

  8. Prioritizing equipment for replacement.

    PubMed

    Capuano, Mike

    2010-01-01

    It is suggested that clinical engineers take the lead in formulating evaluation processes to recommend equipment replacement. Their skill, knowledge, and experience, combined with access to equipment databases, make them a logical choice. Based on ideas from Fennigkoh's scheme, elements such as age, vendor support, accumulated maintenance cost, and function/risk were used.6 Other more subjective criteria such as cost benefits and efficacy of newer technology were not used. The element of downtime was also omitted due to the data element not being available. The resulting Periop Master Equipment List and its rationale was presented to the Perioperative Services Program Council. They deemed the criteria to be robust and provided overwhelming acceptance of the list. It was quickly put to use to estimate required capital funding, justify items already thought to need replacement, and identify high-priority ranked items for replacement. Incorporating prioritization criteria into an existing equipment database would be ideal. Some commercially available systems do have the basic elements of this. Maintaining replacement data can be labor-intensive regardless of the method used. There is usually little time to perform the tasks necessary for prioritizing equipment. However, where appropriate, a clinical engineering department might be able to conduct such an exercise as shown in the following case study.

  9. [Medical Equipment Maintenance Methods].

    PubMed

    Liu, Hongbin

    2015-09-01

    Due to the high technology and the complexity of medical equipment, as well as to the safety and effectiveness, it determines the high requirements of the medical equipment maintenance work. This paper introduces some basic methods of medical instrument maintenance, including fault tree analysis, node method and exclusive method which are the three important methods in the medical equipment maintenance, through using these three methods for the instruments that have circuit drawings, hardware breakdown maintenance can be done easily. And this paper introduces the processing methods of some special fault conditions, in order to reduce little detours in meeting the same problems. Learning is very important for stuff just engaged in this area. PMID:26904890

  10. German mining equipment

    SciTech Connect

    Not Available

    1993-10-01

    The German mining equipment industry developed to supply machines and services to the local mining industry, i.e., coal, lignite, salt, potash, ore mining, industrial minerals, and quarrying. The sophistication and reliability of its technology also won it worldwide export markets -- which is just as well since former major domestic mining sectors such as coal and potash have declined precipitously, and others such as ore mining have all but disappeared. Today, German mining equipment suppliers focus strongly on export sales, and formerly unique German mining technologies such as continuous mining with bucket wheel excavators and conveyors for open pits, or plowing of underground coal longwalls are widely used abroad. The status of the German mining equipment industry is reviewed.

  11. Equipment Operational Requirements

    SciTech Connect

    Greenwalt, B; Henderer, B; Hibbard, W; Mercer, M

    2009-06-11

    The Iraq Department of Border Enforcement is rich in personnel, but poor in equipment. An effective border control system must include detection, discrimination, decision, tracking and interdiction, capture, identification, and disposition. An equipment solution that addresses only a part of this will not succeed, likewise equipment by itself is not the answer without considering the personnel and how they would employ the equipment. The solution should take advantage of the existing in-place system and address all of the critical functions. The solutions are envisioned as being implemented in a phased manner, where Solution 1 is followed by Solution 2 and eventually by Solution 3. This allows adequate time for training and gaining operational experience for successively more complex equipment. Detailed descriptions of the components follow the solution descriptions. Solution 1 - This solution is based on changes to CONOPs, and does not have a technology component. It consists of observers at the forts and annexes, forward patrols along the swamp edge, in depth patrols approximately 10 kilometers inland from the swamp, and checkpoints on major roads. Solution 2 - This solution adds a ground sensor array to the Solution 1 system. Solution 3 - This solution is based around installing a radar/video camera system on each fort. It employs the CONOPS from Solution 1, but uses minimal ground sensors deployed only in areas with poor radar/video camera coverage (such as canals and streams shielded by vegetation), or by roads covered by radar but outside the range of the radar associated cameras. This document provides broad operational requirements for major equipment components along with sufficient operational details to allow the technical community to identify potential hardware candidates. Continuing analysis will develop quantities required and more detailed tactics, techniques, and procedures.

  12. SILEX Beacon equipment

    NASA Astrophysics Data System (ADS)

    Crepin, Pierre-Jean; Leblay, Pierrick; Haller, Regine; Tremillon, Isabelle; Sonon, Jean-Pierre

    1990-07-01

    The design of this equipment based on the use of nineteen 500 mW laser diodes is presented. The Beacon is a powerful and collimated optical source based upon semi-conductor lasers. This equipment is implemented in the SILEX GEO2 terminal and its function is to provide a continuous wave light beam towards the LEO or GEO1 satellites during the acquisition phases. The design was experimentally validated with a functional breadboard, and test results demonstrated the feasibility of every performance required by the SILEX system.

  13. Equipment Management Manual

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The NASA Equipment Management Manual (NHB 4200.1) is issued pursuant to Section 203(c)(1) of the National Aeronautics and Space Act of 1958, as amended (42 USC 2473), and sets forth policy, uniform performance standards, and procedural guidance to NASA personnel for the acquisition, management, and use of NASA-owned equipment. This revision is effective upon receipt. This is a controlled manual, issued in loose-leaf form, and revised through page changes. Additional copies for internal use may be obtained through normal distribution.

  14. Remote maintenance lessons learned'' on prototypical reprocessing equipment

    SciTech Connect

    Kring, C.T.; Schrock, S.L.

    1990-01-01

    Hardware representative of essentially every major equipment item necessary for reprocessing breeder reactor nuclear fuel has been installed and tested for remote maintainability. This testing took place in a cold mock-up of a remotely maintained hot cell operated by the Consolidated Fuel Reprocessing Program (CFRP) within the Fuel Recycle Division at Oak Ridge National Laboratory (ORNL). The reprocessing equipment tested included a Disassembly System, a Shear System, a Dissolver System, an Automated Sampler System, removable Equipment Racks on which various chemical process equipment items were mounted, and an advanced servomanipulator (ASM). These equipment items were disassembled and reassembled remotely by using the remote handling systems that are available within the cold mock-up area. This paper summarizes the lessons learned'' as a result of the numerous maintenance activities associated with each of these equipment items. 4 refs., 3 figs., 1 tab.

  15. Lennox - Student Training Equipment.

    ERIC Educational Resources Information Center

    Lennox Industries, Inc., Marshalltown, IA.

    Presents a series of demonstration units designed by Lennox Industries for the purpose of training students to become familiar with Lennox mechanical equipment. Demonstrators are designed to present technical information in a clear simplified manner thus reducing frustration for the beginning trainee. The following demonstrators are available--(1)…

  16. Engineer Equipment Chief.

    ERIC Educational Resources Information Center

    Marine Corps Inst., Washington, DC.

    This student guide, one of a series of correspondence training courses designed to improve the job performance of members of the Marine Corps, deals with the skills needed by engineer equipment chiefs. Addressed in the five individual units of the course are the following topics: construction management (planning, scheduling, and supervision);…

  17. The EQUIP Program

    ERIC Educational Resources Information Center

    Gibbs, John C.; Potter, Granville Bud; DiBiase, Ann-Marie; Devlin, Renee

    2008-01-01

    Youth who present anti-social behavior need powerful interventions that strengthen empathy, counter negative peer influence, and challenge thinking errors. This article recaps some key points about EQUIP, a Positive Peer Culture (PPC)-based cognitive behavioral intervention program for behaviorally at-risk youth, and notes how the program has…

  18. Dairy Equipment Lubrication

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Lake To Lake Dairy Cooperative, Manitowoc, Wisconsin, operates four plants in Wisconsin for processing milk, butter and cheese products from its 1,300 member farms. The large co-op was able to realize substantial savings by using NASA information for improved efficiency in plant maintenance. Under contract to Marshall Space Flight Center, Midwest Research Institute compiled a handbook consolidating information about commercially available lubricants. The handbook details chemical and physical properties, applications, specifications, test procedures and test data for liquid and solid lubricants. Lake To Lake's plant engineer used the handbook to effect savings in maintenance labor and materials costs by reducing the number of lubricants used on certain equipment. Strict U.S. Department of Agriculture and Food and Drug Administration regulations preclude lubrication changes n production equipment, but the co-op's maintenance chief was able to eliminate seven types of lubricants for ancillary equipment, such as compressors and high pressure pumps. Handbook data enabled him to select comparable but les expensive lubricants in the materials consolidation process, and simplified lubrication schedules and procedures. The handbook is in continuing use as a reference source when a new item of equipment is purchased.

  19. STDN ranging equipment

    NASA Technical Reports Server (NTRS)

    Jones, C. E.

    1975-01-01

    Final results of the Spaceflight Tracking and Data Network (STDN) Ranging Equipment program are summarized. Basic design concepts and final design approaches are described. Theoretical analyses which define requirements and support the design approaches are presented. Design verification criteria are delineated and verification test results are specified.

  20. Equipment & New Products.

    ERIC Educational Resources Information Center

    Poitras, Adrian W., Ed.

    1977-01-01

    Presents information about equipment and new products such as the melting point instrument and TV-microscope coupler which are helpful in college science teaching. Descriptions of each product, how it operates, its prices, and address for ordering are presented. (HM)

  1. Engineer Equipment Operator.

    ERIC Educational Resources Information Center

    Marine Corps Inst., Washington, DC.

    This student guide, one of a series of correspondence training courses designed to improve the job performance of members of the Marine Corps, deals with the skills needed by engineer equipment operators. Addressed in the seven individual units of the course are the following topics: introduction to Military Occupation Specialty (MOS) 1345…

  2. Basic Engineer Equipment Mechanic.

    ERIC Educational Resources Information Center

    Marine Corps Inst., Washington, DC.

    This student guide, one of a series of correspondence training courses designed to improve the job performance of members of the Marine Corps, deals with the skills needed by basic engineer equipment mechanics. Addressed in the four individual units of the course are the following topics: mechanics and their tools (mechanics, hand tools, and power…

  3. JPRS report: Science and technology, [March 12, 1992]. Central Eurasia: Engineering and equipment

    SciTech Connect

    1992-03-12

    This report contains translations/transcriptions of articles and/or broadcasts on engineering and equipment in Central Eurasia. Titles include: on increasing nuclear power plant pipeline reliability during earthquakes; seismic stability of production equipment: seismic stability feasibility analysis of Kozloduy nuclear power plant turbogenerator building pipelines; Ukrainian nuclear security committee; on criteria approximation in dynamic synthesis problems of manipulator robots; and others.

  4. 46 CFR 170.095 - Data submittal for a vessel equipped to lift.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Data submittal for a vessel equipped to lift. 170.095... STABILITY STABILITY REQUIREMENTS FOR ALL INSPECTED VESSELS Plan Approval § 170.095 Data submittal for a vessel equipped to lift. The following data must be submitted with the plans required by § 170.075 if...

  5. 46 CFR 170.095 - Data submittal for a vessel equipped to lift.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Data submittal for a vessel equipped to lift. 170.095... STABILITY STABILITY REQUIREMENTS FOR ALL INSPECTED VESSELS Plan Approval § 170.095 Data submittal for a vessel equipped to lift. The following data must be submitted with the plans required by § 170.075 if...

  6. 46 CFR 170.095 - Data submittal for a vessel equipped to lift.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Data submittal for a vessel equipped to lift. 170.095... STABILITY STABILITY REQUIREMENTS FOR ALL INSPECTED VESSELS Plan Approval § 170.095 Data submittal for a vessel equipped to lift. The following data must be submitted with the plans required by § 170.075 if...

  7. 47 CFR 22.863 - Frequency stability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Frequency stability. 22.863 Section 22.863...-Ground Radiotelephone Service Commercial Aviation Air-Ground Systems § 22.863 Frequency stability. The frequency stability of equipment used under this subpart shall be sufficient to ensure that,...

  8. 47 CFR 22.863 - Frequency stability.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false Frequency stability. 22.863 Section 22.863...-Ground Radiotelephone Service Commercial Aviation Air-Ground Systems § 22.863 Frequency stability. The frequency stability of equipment used under this subpart shall be sufficient to ensure that,...

  9. 47 CFR 22.863 - Frequency stability.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 2 2014-10-01 2014-10-01 false Frequency stability. 22.863 Section 22.863...-Ground Radiotelephone Service Commercial Aviation Air-Ground Systems § 22.863 Frequency stability. The frequency stability of equipment used under this subpart shall be sufficient to ensure that,...

  10. 47 CFR 22.863 - Frequency stability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Frequency stability. 22.863 Section 22.863...-Ground Radiotelephone Service Commercial Aviation Air-Ground Systems § 22.863 Frequency stability. The frequency stability of equipment used under this subpart shall be sufficient to ensure that,...

  11. 47 CFR 22.863 - Frequency stability.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 2 2012-10-01 2012-10-01 false Frequency stability. 22.863 Section 22.863...-Ground Radiotelephone Service Commercial Aviation Air-Ground Systems § 22.863 Frequency stability. The frequency stability of equipment used under this subpart shall be sufficient to ensure that,...

  12. Gene knockout using transcription activator-like effector nucleases (TALENs) reveals that human NDUFA9 protein is essential for stabilizing the junction between membrane and matrix arms of complex I.

    PubMed

    Stroud, David A; Formosa, Luke E; Wijeyeratne, Xiaonan W; Nguyen, Thanh N; Ryan, Michael T

    2013-01-18

    Transcription activator-like effector nucleases (TALENs) represent a promising approach for targeted knock-out of genes in cultured human cells. We used TALEN-technology to knock out the nuclear gene encoding NDUFA9, a subunit of mitochondrial respiratory chain complex I in HEK293T cells. Screening for the knock-out revealed a mixture of NDUFA9 cell clones that harbored partial deletions of the mitochondrial N-terminal targeting signal but were still capable of import. A cell line lacking functional copies of both NDUFA9 alleles resulted in a loss of NDUFA9 protein expression, impaired assembly of complex I, and cells incapable of growth in galactose medium. Cells lacking NDUFA9 contained a complex I subcomplex consisting of membrane arm subunits but not marker subunits of the matrix arm. Re-expression of NDUFA9 restored the defects in complex I assembly. We conclude that NDUFA9 is involved in stabilizing the junction between membrane and matrix arms of complex I, a late assembly step critical for complex I biogenesis and activity.

  13. Treatment of Essential Tremor

    MedlinePlus

    ... essential tremor. Neurologists from the American Academy of Neurology are doctors who identify and treat diseases of ... an educational service of the American Academy of Neurology. It is based on an assessment of current ...

  14. Essential tremor: an overview.

    PubMed

    Metzer, W S

    1994-05-01

    Essential tremor (ET) is typically 4 to 12 Hz frequency, absent at rest, maximal during maintenance of a posture, attenuated during movement and often accentuated at the termination of movement. Prevalence in Americans is 300 to 415 per 100,000 population, and it is frequently disabling. There is controversy about the central or peripheral origin of ET. There is no specific diagnostic test for ET; the diagnosis is made clinically. Ethanol is the most effective suppressor of ET. Treatment is with beta-adrenergic blockers, primidone, and benzodiazepines. The first systematic description of essential tremor (ET) was 100 years ago by Dana in 1887, who regarded the disorder as a hereditary tremor that was a form of "motor neurosis." Most subsequent contributions to the English literature consisted predominantly of case reports until Critchley's exhaustive survey of the subject in 1949. The disorder has been variously termed essential, benign essential, hereditary, familial, idiopathic, juvenile, presenile or senile tremor. PMID:7913460

  15. Artifacts and essentialism

    PubMed Central

    Gelman, Susan A.

    2013-01-01

    Psychological essentialism is an intuitive folk belief positing that certain categories have a non-obvious inner “essence” that gives rise to observable features. Although this belief most commonly characterizes natural kind categories, I argue that psychological essentialism can also be extended in important ways to artifact concepts. Specifically, concepts of individual artifacts include the non-obvious feature of object history, which is evident when making judgments regarding authenticity and ownership. Classic examples include famous works of art (e.g., the Mona Lisa is authentic because of its provenance), but ordinary artifacts likewise receive value from their history (e.g., a worn and tattered blanket may have special value if it was one's childhood possession). Moreover, in some cases, object history may be thought to have causal effects on individual artifacts, much as an animal essence has causal effects. I review empirical support for these claims and consider the implications for both artifact concepts and essentialism. This perspective suggests that artifact concepts cannot be contained in a theoretical framework that focuses exclusively on similarity or even function. Furthermore, although there are significant differences between essentialism of natural kinds and essentialism of artifact individuals, the commonalities suggest that psychological essentialism may not derive from folk biology but instead may reflect more domain-general perspectives on the world. PMID:23976903

  16. HVAC equipment and noise

    SciTech Connect

    Cerami, V.J.

    1996-03-01

    The purpose of this article is to define how the selection of HVAC equipment and layout impact the achievable noise criteria (NC) levels in occupied spaces. It will focus on the design of HVAC systems that employ floor-by-floor air handling/air conditioning units and their acoustical ramifications. This is of increasing importance since tenants require incorporation of noise limits in lease agreements.

  17. The essential oil of olibanum.

    PubMed

    Wahab, S M; Aboutabl, E A; El-Zalabani, S M; Fouad, H A; De Pooter, H L; El-Fallaha, B

    1987-08-01

    The essential oil of the oleogum resin "Olibanum" was prepared by direct steam distillation as well as by steam distillation of an N-hexane extract. Physical and chemical constants of the oil were determined. GC-MS was used for the analysis of the oil. Thirty-three components were identified in the steam distilled oil by their Kováts indices on stabilized OV-1 columns and by mass spectral data. The oil contains 62.1% esters, 15.4% alcohols, 9.9% monoterpene hydrocarbons, and 7.1% diterpenes. Certain minor constituents of the steam distilled oil failed to show up in the oil prepared by steam distillation of the N-hexane extract. Both oils exhibit antimicrobial activity, the activity of the steam distilled oil being higher than that of the oil prepared by steam distillation of the N-hexane extract.

  18. Stabilized Zeeman split laser

    NASA Technical Reports Server (NTRS)

    1981-01-01

    The development of a stablized Zeeman split laser for use in a polarization profilometer is discussed. A Hewlett-Packard laser was modified to stabilize the Zeeman split beat frequency thereby increasing the phase measurement accuracy from the Hewlett-Packard 3 degrees to an accuracy of .01 degrees. The addition of a two layered inductive winding converts the laser to a current controlled oscillator whose frequency is linearly related to coil current. This linear relationship between coil current and laser frequency permits phase locking the laser frequency to a stable crystal controlled reference frequency. The stability of the system is examined and the equipment operation procedures are outlined.

  19. 12. VIEW OF REMOTELY OPERATED EQUIPMENT. OPERATORS VIEWED THE EQUIPMENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. VIEW OF REMOTELY OPERATED EQUIPMENT. OPERATORS VIEWED THE EQUIPMENT THROUGH A WATER-FILLED WINDOW. (10/8/81) - Rocky Flats Plant, Plutonium Recovery Facility, Northwest portion of Rocky Flats Plant, Golden, Jefferson County, CO

  20. Highway Maintenance Equipment Operator. Miscellaneous Equipment. Training Materials.

    ERIC Educational Resources Information Center

    Perky, Sandra Dutreau; And Others

    This curriculum guide provides instructional materials to assist in training equipment operators in the safe and effective use of highway maintenance equipment. It includes six units of instruction covering the small, specialized equipment used in maintenance operations. Each unit of instruction consists of eight basic components: performance…

  1. Getting Equipped and Staying Equipped, Part 2: Finding the Funds.

    ERIC Educational Resources Information Center

    Jordahl, Gregory; Orwig, Ann

    1995-01-01

    Suggests how school libraries can fund computer equipment; gain assistance from high-tech businesses; develop business partnerships and foundations; lease equipment; accept equipment donations; fund raise; build money into the budget; and communicate school needs with budget voters. Sidebars include leasing advice; resources for parent-teacher…

  2. Highway Maintenance Equipment Operator. Specialized Equipment. Training Materials.

    ERIC Educational Resources Information Center

    Perky, Sandra Dutreau; And Others

    This curriculum guide provides instructional materials to assist in training equipment operators in the safe and effective use of highway maintenance equipment. It includes 18 units of instruction covering the large equipment used in maintenance operations. Each unit of instruction consists of eight basic components: performance objectives,…

  3. Psychological essentialism in children.

    PubMed

    Gelman, Susan A

    2004-09-01

    Psychological essentialism is the idea that certain categories, such as "lion" or "female", have an underlying reality that cannot be observed directly. Where does this idea come from? This article reviews recent evidence suggesting that psychological essentialism is an early cognitive bias. Young children look beyond the obvious in many converging ways: when learning words, generalizing knowledge to new category members, reasoning about the insides of things, contemplating the role of nature versus nurture, and constructing causal explanations. These findings argue against the standard view of children as concrete thinkers, instead claiming that children have an early tendency to search for hidden, non-obvious features. PMID:15350241

  4. How to Use Equipment Therapeutically.

    ERIC Educational Resources Information Center

    Bowne, Douglas

    1986-01-01

    Shares therapeutic and economic practices surrounding equipment used in New York's Higher Horizons adventure program of therapy for troubled youth. Encourages educators, therapists, and administrators to explore relationship between equipment selection, program goals, and clients. (NEC)

  5. Precision Instrument and Equipment Repairers.

    ERIC Educational Resources Information Center

    Wyatt, Ian

    2001-01-01

    Explains the job of precision instrument and equipment repairers, who work on cameras, medical equipment, musical instruments, watches and clocks, and industrial measuring devices. Discusses duties, working conditions, employment and earnings, job outlook, and skills and training. (JOW)

  6. Monitoring equipment for multitasking multimicroprocessors

    SciTech Connect

    Negrini, R.; Pozzi, F.; Scarabottolo, N.

    1983-01-01

    The structure of monitoring equipment capable of evaluating performances of multimicroprocessor systems is described. The goals and field of application of such equipment are discussed, along with characteristics both at the hardware and software levels. 4 references.

  7. Decision Analysis for Equipment Selection

    ERIC Educational Resources Information Center

    Cilliers, J. J.

    2005-01-01

    Equipment selection during process design is a critical aspect of chemical engineering and requires engineering judgment and subjective analysis. When educating chemical engineering students in the selection of proprietary equipment during design, the focus is often on the types of equipment available and their operating characteristics. The…

  8. Guidelines for Purchasing Playground Equipment.

    ERIC Educational Resources Information Center

    Neugebauer, Roger

    1998-01-01

    Notes that the purchase of playground equipment is one of the most important decisions center directors make. Offers advice from a number of playground equipment manufacturers that suggests directors consider activities, safety, construction, installation, and warranty when purchasing equipment. Also suggests interviewing other directors about…

  9. Essentials of Professional Growth.

    ERIC Educational Resources Information Center

    Wildman, Terry M.; Niles, Jerry A.

    1987-01-01

    The essentials needed for developing teaching novices into good teachers are autonomy, collaboration, and time. School improvement plans should include an understanding of the conditions that foster the professional growth of teachers. Provides a table and extensive list of references. (MD)

  10. Physical Education: Essential Issues

    ERIC Educational Resources Information Center

    Green, Ken, Ed.; Hardman, Ken, Ed.

    2005-01-01

    This book is aimed primarily at under and postgraduate students pursuing entire programmes or discrete courses and modules in the broad area of physical education and sport in schools. It consists of a collection of what is considered to be essential readings in the sense that they are contributions from eminent authors on a breadth of salient…

  11. System design description PFP thermal stabilization

    SciTech Connect

    LARKIN, K.A.

    1999-02-23

    The purpose of this document is to provide a system design description and design basis for the Plutonium Finishing Plant (PFP) Thermal Stabilization project. The sources of material for this project are residues scraped from glovebox floors and materials already stored in vault storage that need further stabilizing. Stabilizing this material will promote long term storage and reduced worker exposure. This document addresses: functional design, equipment, and safety requirements for thermal stabilization of plutonium residues and oxides.

  12. Benefits of Digital Equipment Generic Qualification Activities

    SciTech Connect

    Thomas, James E.; Steiman, Samuel C.

    2002-07-01

    of Commercial Grade Digital Equipment for Nuclear Safety Applications, and the supplemental guidance of EPRI TR-107339, Evaluating Commercial Digital Equipment for High Integrity Applications. The U.S. Nuclear Regulatory Commission (NRC) has reviewed some of the qualification activities and reports and issued a number of Safety Evaluation Reports (SERs). Although some additional work may be required to support specific applications, the generic qualification activities and NRC reviews have provided significant clarification and further stabilized the regulatory environment for use of digital equipment in safety-related applications. (authors)

  13. Seismic qualification of unanchored equipment

    SciTech Connect

    Moran, T.J.

    1995-12-01

    This paper describes procedures used to design and qualify unanchored equipment to survive Seismic events to the PC = 4 level in a moderate seismic area. The need for flexibility to move experimental equipment together with the requirements for remote handling in a highly-radioactive non-reactor nuclear facility precluded normal equipment anchorage. Instead equipment was designed to remain stable under anticipated DBE floor motions with sufficient margin to achieve the performance goal. The equipment was also designed to accommodate anticipated sliding motions with sufficient. The simplified design criteria used to achieve these goals were based on extensive time-history simulations of sliding, rocking, and overturning of generic equipment models. The entire process was subject to independent peer review and accepted in a Safety Evaluation Report. The process provides a model suitable for adaptation to similar applications and for assessment of the potential for seismic damage of existing, unanchored equipment In particular, the paper describes: (1) Two dimensional sliding studies of deformable equipment subject to 3-D floor excitation as the basis for simplified sliding radius and sliding velocity design criteria. (2) Two dimensional rocking and overturning simulations of rigid equipment used to establish design criteria for minimum base dimensions and equipment rigidity to prevent overturning. (3) Assumed mode rocking analyses of deformable equipment models used to establish uplift magnitudes and subsequent impacts during stable rocking motions. The model used for these dynamic impact studies is reported elsewhere.

  14. Biomedical equipment and medical services in India.

    PubMed

    Sahay, K B; Saxena, R K

    Varieties of Biomedical Equipment (BME) are now used for quick diagnosis, flawless surgery and therapeutics etc. Use of a malfunctioning BME could result in faulty diagnosis and wrong treatment and can lead to damaging or even devastating aftermath. Modern Biomedical Equipments inevitably employ highly sophisticated technology and use complex systems and instrumentation for best results. To the best of our knowledge the medical education in India does not impart any knowledge on the theory and design of BME and it is perhaps not possible also. Hence there is need for a permanent mechanism which can maintain and repair the biomedical equipments routinely before use and this can be done only with the help of qualified Clinical Engineers. Thus there is a genuine need for well organized cadre of Clinical Engineers who would be persons with engineering background with specialization in medical instrumentation. These Clinical engineers should be made responsible for the maintenance and proper functioning of BME. Every hospital or group of hospitals in the advanced countries has a clinical engineering unit that takes care of the biomedical equipments and systems in the hospital by undertaking routine and preventive maintenance, regular calibration of equipments and their timely repairs. Clinical engineers should be thus made an essential part of modern health care system and services. Unfortunately such facilities and mechanism do not exist in India. To make BME maintenance efficient and flawless in India, study suggests following measures and remedies: (i) design and development of comprehensive computerized database for BME (ii) cadre of Clinical engineers (iii) online maintenance facility and (iv) farsighted managerial skill to maximize accuracy, functioning and cost effectiveness. PMID:10166967

  15. Commercial cooking equipment improvement

    SciTech Connect

    Himmel, R.L.

    1981-10-01

    A program to improve the efficiency of gas-fired commercial cooking equipment has focused on deep-fat fryers and the oven, open-top, hot-top, and fry-top sections of ranges. A newly developed infrared deep-fat fryer provided to be 25% more efficient than conventional units. Using the direct-fired forced-convection approach in an oven reduced the fuel consumed during baking by 55%. A range open-top burner system with an experimental power burner consumed 33% less fuel and time than conventional models. Preliminary modifications to heavy-duty hot-top and fry-top sections demonstrated fuel savings of 43% and 30%, respectively. More R and D is planned to incorporate manufacturer suggestions resulting in more complete experimental models that will aid in commercializing these improved appliances.

  16. Orbital construction support equipment

    NASA Technical Reports Server (NTRS)

    1977-01-01

    Approximately 200 separate construction steps were defined for the three solar power satellite (SPS) concepts. Detailed construction scenarios were developed which describe the specific tasks to be accomplished, and identify general equipment requirements. The scenarios were used to perform a functional analysis, which resulted in the definition of 100 distinct SPS elements. These elements are the components, parts, subsystems, or assemblies upon which construction activities take place. The major SPS elements for each configuration are shown. For those elements, 300 functional requirements were identified in seven generic processes. Cumulatively, these processes encompass all functions required during SPS construction/assembly. Individually each process is defined such that it includes a specific type of activity. Each SPS element may involve activities relating to any or all of the generic processes. The processes are listed, and examples of the requirements defined for a typical element are given.

  17. Pharmacotherapy of Essential Tremor

    PubMed Central

    Hedera, Peter; Cibulčík, František; Davis, Thomas L.

    2013-01-01

    Essential tremor (ET) is a common movement disorder but its pathogenesis remains poorly understood. This has limited the development of effective pharmacotherapy. The current therapeutic armamentaria for ET represent the product of careful clinical observation rather than targeted molecular modeling. Here we review their pharmacokinetics, metabolism, dosing, and adverse effect profiles and propose a treatment algorithm. We also discuss the concept of medically refractory tremor, as therapeutic trials should be limited unless invasive therapy is contraindicated or not desired by patients. PMID:24385718

  18. Causal essentialism in kinds.

    PubMed

    Ahn, Woo-kyoung; Taylor, Eric G; Kato, Daniel; Marsh, Jessecae K; Bloom, Paul

    2013-06-01

    The current study examines causal essentialism, derived from psychological essentialism of concepts. We examine whether people believe that members of a category share some underlying essence that is both necessary and sufficient for category membership and that also causes surface features. The main claim is that causal essentialism is restricted to categories that correspond to our intuitive notions of existing kinds and hence is more attenuated for categories that are based on arbitrary criteria. Experiments 1 and 3 found that people overtly endorse causal essences in nonarbitrary kinds but are less likely to do so for arbitrary categories. Experiments 2 and 4 found that people were more willing to generalize a member's known causal relations (or lack thereof) when dealing with a kind than when dealing with an arbitrary category. These differences between kinds and arbitrary categories were found across various domains-not only for categories of living things, but also for artefacts. These findings have certain real-world implications, including how people make sense of mental disorders that are treated as real kinds. PMID:23098315

  19. 29 CFR 1926.600 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Motor Vehicles, Mechanized Equipment, and Marine... equipment is parked, the parking brake shall be set. Equipment parked on inclines shall have the...

  20. Sludge stabilization operability test report

    SciTech Connect

    Lewis, W.S.

    1994-11-08

    Document provides the results of the Operability Test Procedure performed to test the operability of the HC-21C thermal stabilization process for sludge. The OTP assured all equipment functioned properly and established the baseline temperature profile for glovebox HC-21C.

  1. Material stabilization characterization management plan

    SciTech Connect

    GIBSON, M.W.

    1999-08-31

    This document presents overall direction for characterization needs during stabilization of SNM at the Plutonium Finishing Plant (PFP). Technical issues for needed data and equipment are identified. Information on material categories and links to vulnerabilities are given. Comparison data on the material categories is discussed to assist in assessing the relative risks and desired processing priority.

  2. Gender and Psychological Essentialism

    PubMed Central

    Heyman, Gail D.; Giles, Jessica W.

    2010-01-01

    SUMMARY When individuals reason in an essentialist way about social categories, they assume that group differences reflect inherently different natures (Gelman, 2003; Rothbart & Taylor, 1992). This paper describes the psychological and social implications of essentialist beliefs, and examines the extent to which children exhibit psychological essentialism when reasoning about gender. The authors discuss reasons young children as well as older children show essentialist reasoning in some contexts, but not in others. Finally, the authors suggest directions for future research, and discuss a primary challenge to many working in this field: reduction of rigid gender beliefs. PMID:21528097

  3. VIEW OF MICROMACHINING, HIGH PRECISION EQUIPMENT USED TO CUSTOM MAKE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF MICRO-MACHINING, HIGH PRECISION EQUIPMENT USED TO CUSTOM MAKE SMALL PARTS. LUMPS OF CLAY; SHOWN IN THE PHOTOGRAPH, WERE USED TO STABILIZE PARTS BEING MACHINED. (11/1/87) - Rocky Flats Plant, Stainless Steel & Non-Nuclear Components Manufacturing, Southeast corner of intersection of Cottonwood & Third Avenues, Golden, Jefferson County, CO

  4. Information technology equipment cooling system

    DOEpatents

    Schultz, Mark D.

    2014-06-10

    According to one embodiment, a system for removing heat from a rack of information technology equipment may include a sidecar indoor air to liquid heat exchanger that cools warm air generated by the rack of information technology equipment. The system may also include a liquid to liquid heat exchanger and an outdoor heat exchanger. The system may further include configurable pathways to connect and control fluid flow through the sidecar heat exchanger, the liquid to liquid heat exchanger, the rack of information technology equipment, and the outdoor heat exchanger based upon ambient temperature and/or ambient humidity to remove heat from the rack of information technology equipment.

  5. Orbiter electrical equipment utilization baseline

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The baseline for utilization of Orbiter electrical equipment in both electrical and Environmental Control and Life Support System (ECLSS) thermal analyses is established. It is a composite catalog of Space Shuttle equipment, as defined in the Shuttle Operational Data Book. The major functions and expected usage of each component type are described. Functional descriptions are designed to provide a fundamental understanding of the Orbiter electrical equipment, to insure correlation of equipment usage within nominal analyses, and to aid analysts in the formulation of off-nominal, contingency analyses.

  6. 141. ARAIII Equipment location plan. Includes list of equipment and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    141. ARA-III Equipment location plan. Includes list of equipment and location in reactor, control, and other buildings. Aerojet-general 880-area/GCRE-101-U-1. Date: February 1958. Ineel index code no. 063-0101-65-013-192508. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  7. VIEW OF ULTRASONIC TESTING EQUIPMENT IN BUILDING 991. THIS EQUIPMENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF ULTRA-SONIC TESTING EQUIPMENT IN BUILDING 991. THIS EQUIPMENT NON-DESTRUCTIVELY TESTS WEAPONS COMPONENTS FOR FLAWS AND CRACKS. (9/11/85) - Rocky Flats Plant, Final Assembly & Shipping, Eastern portion of plant site, south of Spruce Avenue, east of Tenth Street & north of Central Avenue, Golden, Jefferson County, CO

  8. Power Product Equipment Technician: Equipment Systems. Teacher Edition. Student Edition.

    ERIC Educational Resources Information Center

    Hilley, Robert

    This packet contains teacher and student editions on the topic of equipment systems, intended for the preparation of power product equipment technicians. This publication contains seven units: (1) principles of power transmission; (2) mechanical drive systems; (3) principles of fluid power; (4) hydraulic and pneumatic drive systems; (5) wheel and…

  9. A compact equipment package for vestibular experiments during spaceflight

    NASA Astrophysics Data System (ADS)

    Clarke, A. H.; Teiwes, W.; Scherer, H.

    A compact measurement and stimulus equipment package for vestibular testing is described. The package is designed on a modular concept so that a customized version can be assembled for each experimental situation. Although primarily conceived for space-related research, the equipment has also been introduced successfully into the clinical diagnostic procedure. An essential function of the equipment is the recording and evaluation of eye movements. This is performed by a video-based measurement system which permits evaluation of horizontal, vertical and torsional components of eye movement. Objective testing of the vestibulo-ocular reflex in all three orthogonal planes is therefore possible. Furthermore evaluation of the otolithic function in weightlessness is made feasible by the possibility of measuring dynamic ocular counterrolling. Some applications of the equipment are described.

  10. Comprehensive framework for preventive maintenance priority of medical equipment.

    PubMed

    Saleh, Neven; Balestra, Gabriella

    2015-08-01

    Throughout the medical equipment life cycle, preventive maintenance is considered one of the most important stages that should be managed properly. However, the need for better management and control by giving a reasonable prioritization for preventive maintenance becomes essential. The purpose of this study is to develop a comprehensive framework for preventive maintenance priority of medical equipment using Quality Function Deployment (QFD) and Fuzzy Logic (FL). The quality function deployment is proposed in order to identify the most important criteria that could impact preventive maintenance priority decision; meanwhile the role of the fuzzy logic is to generate a priority index of the list of equipment considering those criteria. The model validation was carried out on 140 pieces of medical equipment belonging to two hospitals. In application, we propose to classify the priority index into five classes. The results indicate that the strong correlation existence between risk-based criteria and preventive maintenance priority decision. PMID:26736488

  11. Comprehensive framework for preventive maintenance priority of medical equipment.

    PubMed

    Saleh, Neven; Balestra, Gabriella

    2015-08-01

    Throughout the medical equipment life cycle, preventive maintenance is considered one of the most important stages that should be managed properly. However, the need for better management and control by giving a reasonable prioritization for preventive maintenance becomes essential. The purpose of this study is to develop a comprehensive framework for preventive maintenance priority of medical equipment using Quality Function Deployment (QFD) and Fuzzy Logic (FL). The quality function deployment is proposed in order to identify the most important criteria that could impact preventive maintenance priority decision; meanwhile the role of the fuzzy logic is to generate a priority index of the list of equipment considering those criteria. The model validation was carried out on 140 pieces of medical equipment belonging to two hospitals. In application, we propose to classify the priority index into five classes. The results indicate that the strong correlation existence between risk-based criteria and preventive maintenance priority decision.

  12. Slope stability and stabilization methods

    SciTech Connect

    Abramson, L.W.; Lee, T.S.; Boyce, G.M.; Sharma, S.S.

    1995-12-01

    Slope stability can be a major problem during the construction of surface facilities. Cutting into existing ground disturbs the mechanics of the surrounding area, which can result in landslides and rock falls. This practical reference gives you the comprehensive information you need for slope stability analysis, suitable methods of analysis with and without the use of computers, and examples of common stability problems and stabilization methods for cuts and fills. It includes detailed discussions of methods used in slope stability analysis, including the Ordinary Method of Slices, Simplified Janbu Method, Simplified Bishop Method, Spencer`s Method, other limit equilibrium methods, numerical methods, total stress analysis, effective stress analysis, and the use of computer programs to solve problems. Chapters include: General Slope Stability Concepts; Engineering Geology Principles; Groundwater Conditions; Geologic Site Exploration; Laboratory Testing Interpretation; Slope Stability Concepts; Slope Stabilization Methods; and Design, Construction and Maintenance.

  13. ISAARE: Information System for Adaptive, Assistive, and Recreational Equipment: Volume I: Existence; Volume II, Communication; Volume V, Adaptation.

    ERIC Educational Resources Information Center

    Melichar, Joseph F.

    Described as part of the Information System for Adaptive, Assistive and Recreational Equipment are equipment items for physically handicapped pupils in the functional areas of existence, equipment and adaptation. Reviewed in the existence section are such items as assistive food containers and container stabilizers, feeder accessories, bowel and…

  14. An overview of non-road equipment emissions in China

    NASA Astrophysics Data System (ADS)

    Wang, Fan; Li, Zhen; Zhang, Kaishan; Di, Baofeng; Hu, Baomei

    2016-05-01

    As the vehicle population has dramatically increased in China in the past two decades, vehicle emissions have become one of the major sources to air pollution across the entire country, especially for the metropolitan cities such as Beijing and Shanghai. Most of the non-road equipment are diesel-fueled and have been proved to be a key source for NOx and PM emissions, contributing significantly to the formation of haze/smog. Therefore, an accurate estimation of emission inventory from non-road equipment is essential for air quality improvement policy making, which mainly depends on the data availability of equipment population, activity, and emissions factor. Compared to on-road vehicles, less studies regarding emissions characterization have been conducted and investigated for non-road mobile sources in China. Thus, in order to identify the data gaps and future research needs, the objective of this study is to review the current status of research in non-road mobile emissions. Five types of non-road equipment were addressed in this study, including agricultural equipment, industrial equipment, river/ocean-going vessels, locomotives, and commercial airplanes, with a focus on the former two. The equipment are further classified mainly based on national standards and data availability to account for fuel type, job duties and others. This investigation has found that the research regarding emissions from non-road equipment is still at its early stage and there is a huge data gap for both activity and emissions factors. For most of the study, data used for emission inventory estimation were based on either literature with similar equipment or as-developed emissions models such as NONROAD or CORPERT. The representativeness of these data to the localities was not much discussed in those studies, which might have weakened the accuracy of the estimated emission inventory. For future study, real-world in-use measurements of activities and emissions for the non-road equipment

  15. 46 CFR 108.301 - Stability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Stability. 108.301 Section 108.301 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Stability... Mobile Offshore Drilling Units....

  16. 46 CFR 108.301 - Stability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Stability. 108.301 Section 108.301 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Stability... Mobile Offshore Drilling Units....

  17. 46 CFR 108.301 - Stability.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Stability. 108.301 Section 108.301 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Stability... Mobile Offshore Drilling Units....

  18. 46 CFR 108.301 - Stability.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Stability. 108.301 Section 108.301 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Stability... Mobile Offshore Drilling Units....

  19. 46 CFR 108.301 - Stability.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Stability. 108.301 Section 108.301 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Stability... Mobile Offshore Drilling Units....

  20. TQM: the essential concepts.

    PubMed

    Chambers, D W

    1998-01-01

    This is an introduction to the major concepts in total quality management, a loose collection of management approaches that focus on continuous improvement of processes, guided by routine data collection and adjustment of the processes. Customer focus and involvement of all members of an organization are also characteristics commonly found in TQM. The seventy-five-year history of the movement is sketched from its beginning in statistical work on quality assurance through the many improvements and redefinitions added by American and Japanese thinkers. Essential concepts covered include: control cycles, focus on the process rather than the defects, the GEAR model, importance of the customer, upstream quality, just-in-time, kaizen, and service quality.

  1. Essential biodiversity variables

    USGS Publications Warehouse

    Pereira, H.M.; Ferrier, S.; Walters, M.; Geller, G.N.; Jongman, R.H.G.; Scholes, R.J.; Bruford, M.W.; Brummitt, N.; Butchart, S.H.M.; Cardoso, A.C.; Coops, N.C.; Dulloo, E.; Faith, D.P.; Freyhof, J.; Gregory, R.D.; Heip, C.; Höft, R.; Hurtt, G.; Jetz, W.; Karp, D.S.; McGeoch, M.A.; Obura, D.; Onada, Y.; Pettorelli, N.; Reyers, B.; Sayre, R.; Scharlemann, J.P.W.; Stuart, S.N.; Turak, E.; Walpole, M.; Wegmann, M.

    2013-01-01

    Reducing the rate of biodiversity loss and averting dangerous biodiversity change are international goals, reasserted by the Aichi Targets for 2020 by Parties to the United Nations (UN) Convention on Biological Diversity (CBD) after failure to meet the 2010 target (1, 2). However, there is no global, harmonized observation system for delivering regular, timely data on biodiversity change (3). With the first plenary meeting of the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) soon under way, partners from the Group on Earth Observations Biodiversity Observation Network (GEO BON) (4) are developing—and seeking consensus around—Essential Biodiversity Variables (EBVs) that could form the basis of monitoring programs worldwide.

  2. [State of the art and outlook for promoting Russian-made hemodialysis equipment with regeneration of dialyzing solution].

    PubMed

    Viktorov, V A; Varin, A N; Grinval'd, V M; Maksimov, E P; Fomicheva, N N; Zavalishin, Iu K; Leshchinskiĭ, G M; Razhev, I I; Noskov, S G; Shadiev, B Sh; Rodin, V V; Strelkov, S I; Shukov, O V; Turiaev, A D; Shishkin, S V

    2003-01-01

    Radical improvements in the physiological features and self-sufficiency of hemodialysis equipment, an essential reduction of the volume of dialyzate contacting with patient's body and elimination of dependence of the equipment operation on the availability of a water-supply network can be ensured by applying a regime of circulation of a relatively small volume (3-5 l) of dialyzate through the regenerating device. The regeneration unit must eliminate the organic products of dialysis from the dialyzate and stabilize the ionic composition of the purified dialyzate according to the preset parameters. Modern methods and technical means for regenerating the used dialyzate are discussed; a regeneration unit, which ensures an electrochemical oxidation (in the used dialyzate) of nitrogen-containing organic metabolites with a subsequent sorption-type additional purification of electrochemically-processed dialyzate, is offered. The regeneration unit is made up of an electrolyser, a sorption-type additional-purification device and a gas utilizer; it eliminates organic metabolites, phosphorus, calcium and potassium from the used dialyzate and stabilizes the pH solution.

  3. Food Service Equipment. Third Edition.

    ERIC Educational Resources Information Center

    Jernigan, Anna Katherine; Ross, Lynne Nannen

    This book provides information that will help in purchasing the kind of food service equipment most useful in any given facility. Hence, it should be of value to architects, contractors, administrators, dietitians, managers, and others involved in remodeling a facility, replacing equipment, and/or improving the efficiency of food service…

  4. Heavy Equipment Mechanic. Instructor Edition.

    ERIC Educational Resources Information Center

    Hendrix, Laborn J.; And Others

    This manual is intended to assist heavy equipment instructors in teaching the latest concepts and functions of heavy equipment. It includes 7 sections and 27 instructional units. Sections (and units) are: orientation (shop safety and first aid, hand tools and miscellaneous tools, measuring, basic rigging and hoisting), engines (basic engine…

  5. Food Service Equipment and Appurtenances.

    ERIC Educational Resources Information Center

    National Sanitation Foundation, Ann Arbor, MI.

    Equipment design specifications are presented relating to tables of all kinds, counters, sinks and drainboards, bins, shelves, drawers, hoods and similar kitchen appurtenances, not including baking, roasting, toasting, broiling or frying equipment, food preparation machinery such as slicers, choppers, and cutters, mixers and grinders, steam…

  6. Day Care: Facilities and Equipment.

    ERIC Educational Resources Information Center

    Campbell, Sheila; And Others

    This collection of 4 bilingual papers on facilities and equipment in day care centers is part of a series of papers on various aspects of day care published by the Canadian Department of Health and Welfare. Each paper is presented in both English and French. Paper I, concerning space and equipment in the playground, consists of short lists of…

  7. Available Equipment in School Foodservice.

    ERIC Educational Resources Information Center

    Meyer, Mary Kay

    This report provides data on the National Food Service Management Institute's multi-year research project that identified type, style, age, and condition of available food service equipment in K-12 schools nationwide. The study found that smaller schools, serving less than 400 lunches per day, had kitchens equipped with ranges, small…

  8. Dental operatory design and equipment.

    PubMed

    Floyd, M

    1993-08-01

    Improving and expanding the dental services of a practice can involve purchasing new equipment and even modifying or expanding the physical plant. Operatory design is important to the efficiency with which dental procedures can be performed. Equipment purchases to outfit the dental operatory should be made based on the specific needs and functions of a practice.

  9. Heavy Equipment Mechanic Program Guide.

    ERIC Educational Resources Information Center

    Georgia Univ., Athens. Dept. of Vocational Education.

    Designed to train an entry-level mechanic, this heavy equipment mechanic program guide presents the standard curriculum for technical institutes in Georgia. The curriculum addresses the minimum competencies for a heavy equipment mechanic program. The general information section contains the following: purpose and objectives; program description,…

  10. Information technology equipment cooling method

    SciTech Connect

    Schultz, Mark D.

    2015-10-20

    According to one embodiment, a system for removing heat from a rack of information technology equipment may include a sidecar indoor air to liquid heat exchanger that cools air utilized by the rack of information technology equipment to cool the rack of information technology equipment. The system may also include a liquid to liquid heat exchanger and an outdoor heat exchanger. The system may further include configurable pathways to connect and control fluid flow through the sidecar heat exchanger, the liquid to liquid heat exchanger, the rack of information technology equipment, and the outdoor heat exchanger based upon ambient temperature and/or ambient humidity to remove heat generated by the rack of information technology equipment.

  11. Aeration equipment for small depths

    NASA Astrophysics Data System (ADS)

    Sluše, Jan; Pochylý, František

    2015-05-01

    Deficit of air in water causes complications with cyanobacteria mainly in the summer months. Cyanobacteria is a bacteria that produces poison called cyanotoxin. When the concentration of cyanobacteria increases, the phenomena "algal bloom" appears, which is very toxic and may kill all the organisms. This article describes new equipment for aeration of water in dams, ponds and reservoirs with small depth. This equipment is mobile and it is able to work without any human factor because its control is provided by a GPS module. The main part of this equipment consists of a floating pump which pumps water from the surface. Another important part of this equipment is an aerator where water and air are blended. Final aeration process runs in the nozzles which provide movement of all this equipment and aeration of the water. Simulations of the flow are solved by multiphase flow with diffusion in open source program called OpenFOAM. Results will be verified by an experiment.

  12. Laser Frequency Stabilization

    NASA Technical Reports Server (NTRS)

    Donelan, Darsa; Mueller, Guido; Thorpe, James; Livas, Jeffrey

    2011-01-01

    Laser ranging and interferometry are essential technologies allowing for many astounding new spacebased missions such as the Laser Interferometer Space Antenna (LISA) to measure gravitational radiation emitted from distant super massive black hole mergers or distributed aperture telescopes with unprecedented angular resolution in the NIR or visible regime. The requirements on laser frequency noise depend on the residual motion and the distances between the spacecraft forming the interferometer. The intrinsic frequency stability of commercial lasers is several orders of magnitude above these requirements. Therefore, it is necessary for lasers to be stabilized to an ultrastable frequency reference so that they can be used to sense and control distances between spacecraft. Various optical frequency references and frequency stabilization schemes are considered and investigated for the applicability and usefulness for space-based interferometry missions.

  13. Mechanism of adenylate kinase. Are the essential lysines essential?

    PubMed

    Tian, G C; Yan, H G; Jiang, R T; Kishi, F; Nakazawa, A; Tsai, M D

    1990-05-01

    Using site-specific mutagenesis, we have probed the structural and functional roles of lysine-21 and lysine-27 of adenylate kinase (AK) from chicken muscle expressed in Escherichia coli. The two residues were chosen since according to the nuclear magnetic resonance (NMR) model [Mildvan, A. S., & Fry, D. C. (1987) Adv. Enzymol. 58, 241-313], they are located near the alpha- and the gamma-phosphates, respectively, of adenosine 5'-triphosphate (ATP) in the AK-MgATP complex. In addition, a lysine residue (Lys-21 in the case of AK) along with a glycine-rich loop is considered "essential" in the catalysis of kinases and other nucleotide binding proteins. The Lys-27 to methionine (K27M) mutant showed only slight increases in kcat and Km, but a substantial increase (1.8 kcal/mol) in the free energy of unfolding, relative to the WT AK. For proper interpretation of the steady-state kinetic data, viscosity-dependent kinetics was used to show that the chemical step is partially rate-limiting in the catalysis of AK. Computer modeling suggested that the folded form of K27M could gain stability (relative to the wild type) via hydrophobic interactions of Met-27 with Val-179 and Phe-183 and/or formation of a charge-transfer complex between Met-27 and Phe-183. The latter was supported by an upfield shift of the methyl protons of Met-27 in 1H NMR. Other than this, the 1H NMR spectrum of K27M is very similar to that of WT, suggesting little perturbation in the global or even local conformations.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2161682

  14. Manganese exposure, essentiality & toxicity.

    PubMed

    Santamaria, A B

    2008-10-01

    Manganese (Mn) is an essential element present in all living organisms and is naturally present in rocks, soil, water, and food. Exposure to high oral, parenteral, or ambient air concentrations of Mn can result in elevations in Mn tissue levels and neurological effects. However, current understanding of the impact of Mn exposure on the nervous system leads to the hypothesis that there should be no adverse effects at low exposures, because Mn is an essential element; therefore, there should be some threshold for exposure above which adverse effects may occur and adverse effects may increase in frequency with higher exposures beyond that threshold. Data gaps regarding Mn neurotoxicity include what the clinical significance is of the neurobehavioural, neuropsychological, or neurological endpoints measured in many of the occupational studies that have evaluated cohorts exposed to relatively low levels of Mn. Specific early biomarkers of effect, such as subclinical neurobehavioural or neurological changes or magnetic resonance imaging (MRI) changes have not been established or validated for Mn, although some studies have attempted to correlate biomarkers with neurological effects. Experimental studies with rodents and monkeys provide valuable information about the absorption, bioavailability, and tissue distribution of various Mn compounds with different solubilities and oxidation states in different age groups. Studies have shown that rodents and primates maintain stable tissue manganese levels as a result of homeostatic mechanisms that tightly regulate absorption and excretion. In addition, physiologically based pharmacokinetic (PBPK) models are being developed to provide for the ability to conduct route-to-route extrapolations, evaluate nasal uptake to the CNS, and evaluate lifestage differences in Mn pharmacokinetics. Such models will facilitate more rigorous quantitative analysis of the available pharmacokinetic data for Mn and will be used to identify situations

  15. Zinc: An Essential Micronutrient

    PubMed Central

    SAPER, ROBERT B.; RASH, REBECCA

    2009-01-01

    Zinc is an essential micronutrient for human metabolism that catalyzes more than 100 enzymes, facilitates protein folding, and helps regulate gene expression. Patients with malnutrition, alcoholism, inflammatory bowel disease, and malabsorption syndromes are at an increased risk of zinc deficiency. Symptoms of zinc deficiency are nonspecific, including growth retardation, diarrhea, alopecia, glossitis, nail dystrophy, decreased immunity, and hypogonadism in males. In developing countries, zinc supplementation may be effective for the prevention of upper respiratory infection and diarrhea, and as an adjunct treatment for diarrhea in malnourished children. Zinc in combination with antioxidants may be modestly effective in slowing the progression of intermediate and advanced age-related macular degeneration. Zinc is an effective treatment for Wilson disease. Current data do not support zinc supplementation as effective for upper respiratory infection, wound healing, or human immunodeficiency virus. Zinc is well tolerated at recommended dosages. Adverse effects of long-term high-dose zinc use include suppressed immunity, decreased high-density lipoprotein cholesterol levels, anemia, copper deficiency, and possible genitourinary complications. PMID:20141096

  16. International Continence Society guidelines on urodynamic equipment performance.

    PubMed

    Gammie, Andrew; Clarkson, Becky; Constantinou, Chris; Damaser, Margot; Drinnan, Michael; Geleijnse, Geert; Griffiths, Derek; Rosier, Peter; Schäfer, Werner; Van Mastrigt, Ron

    2014-04-01

    These guidelines provide benchmarks for the performance of urodynamic equipment, and have been developed by the International Continence Society to assist purchasing decisions, design requirements, and performance checks. The guidelines suggest ranges of specification for uroflowmetry, volume, pressure, and EMG measurement, along with recommendations for user interfaces and performance tests. Factors affecting measurement relating to the different technologies used are also described. Summary tables of essential and desirable features are included for ease of reference. It is emphasized that these guidelines can only contribute to good urodynamics if equipment is used properly, in accordance with good practice.

  17. Anesthesia equipment for the oral and maxillofacial surgery practice.

    PubMed

    Chung, William L

    2013-08-01

    The physical design of an oral and maxillofacial surgeon's office is highly individualized and unique. Every office must incorporate certain essential equipment and features to safely deliver office anesthesia, regardless of the scope of anesthesia services provided. Furthermore, the office design and anesthesia armamentarium must take into account patient safety and comfort. This article discusess the necessary elements, ranging from preanesthesia assessment forms and intraoperative records to office design, anesthesia monitors, and equipment related to the safe and successful administration of office-based anesthesia by oral and maxillofacial surgeons and their staff.

  18. TRANSPORT AND EMPLACEMENT EQUIPMENT DESCRIPTIONS

    SciTech Connect

    NA

    1997-09-29

    The objective and the scope of this document are to list and briefly describe the major mobile equipment necessary for waste package (WP) Transport and Emplacement in the proposed subsurface nuclear waste repository at Yucca Mountain. Primary performance characteristics and some specialized design features of the equipment are explained and summarized in the individual subsections of this document. The Transport and Emplacement equipment described in this document consists of the following: (1) WP Transporter; (2) Reusable Rail Car; (3) Emplacement Gantry; (4) Gantry Carrier; and (5) Transport Locomotive.

  19. Membrane stabilizer

    DOEpatents

    Mingenbach, William A.

    1988-01-01

    A device is provided for stabilizing a flexible membrane secured within a frame, wherein a plurality of elongated arms are disposed radially from a central hub which penetrates the membrane, said arms imposing alternately against opposite sides of the membrane, thus warping and tensioning the membrane into a condition of improved stability. The membrane may be an opaque or translucent sheet or other material.

  20. Rig safety depends on equipment, regulations, and personnel

    SciTech Connect

    Bates, T.R. Jr.; Tait, S. ); Mumford, G. )

    1990-03-05

    The authors discuss how improvements that can increase rig safety can be made in equipment, regulations, and stabilized personnel levels. With regard to equipment, exposure to material handling must be reduced through automation, and well-control technology must be improved by enhanced use of computers and better systems to handle gas. According to this analysis, regulations are needed that are global in scope and have had their costs-to-benefits fully and fairly assessed. Self regulation must be used effectively throughout the industry. Job security and wages should be made adequate to maintain an experienced, motivated, and safe work force.

  1. Water-Using Equipment: Domestic

    SciTech Connect

    Solana, Amy E.; Mcmordie, Katherine

    2006-01-24

    Water management is an important aspect of energy engineering. This article addresses water-using equipment primarily used for household purposes, including faucets, showers, toilets, urinals, dishwashers, and clothes washers, and focuses on how the equipment can be optimized to save both water and energy. Technology retrofits and operation and maintenance changes are the primary methods discussed for water and energy conservation. Auditing to determine current consumption rates is also described for each technology.

  2. Postoutbreak disinfection of mobile equipment.

    PubMed

    Alphin, R L; Ciaverelli, C D; Hougentogler, D P; Johnson, K J; Rankin, M K; Benson, E R

    2010-03-01

    Current control strategies for avian influenza virus, exotic Newcastle disease, and other highly contagious poultry diseases include surveillance, quarantine, depopulation, disposal, and decontamination. Skid steer loaders and other mobile equipment are extensively used during depopulation and disposal. Movement of contaminated equipment has been implicated in the spread of disease in previous outbreaks. One approach to equipment decontamination is to power wash the equipment, treat with a liquid disinfectant, change any removable filters, and let it sit idle for several days. In this project, multiple disinfectant strategies were individually evaluated for their effectiveness at inactivating Newcastle disease virus (NDV) on mechanical equipment seeded with the virus. A small gasoline engine was used to simulate typical mechanical equipment. A high titer of LaSota strain, NDV was applied and dried onto a series of metal coupons. The coupons were then placed on both interior and exterior surfaces of the engine. Liquid disinfectants that had been effective in the laboratory were not as effective at disinfecting the engine under field conditions. Indirect thermal fog showed a decrease in overall virus titer or strength. Direct thermal fog was more effective than liquid spray application or indirect thermal fog application. PMID:20521731

  3. Difficult airway equipment: a survey of standards across metropolitan Perth.

    PubMed

    Alakeson, N; Flett, T; Hunt, V; Ramgolam, A; Reynolds, W; Hartley, K; Hegarty, M; von Ungern-Sternberg, B S

    2014-09-01

    The importance of appropriate equipment to manage the difficult airway has been highlighted by the publication of the Australian and New Zealand College of Anaesthetists (ANZCA) guidelines in 2012. We set out to audit compliance with these guidelines in all public and private sites providing general anaesthesia in metropolitan Perth. Public and private health care websites identified 39 sites of which 37 were studied. Institutional and ethics approval was obtained. A tick-box design audit tool, based on the ANZCA guidelines, was used to collect information regarding the dedicated difficult airway container (DDAC) at each site. As recommended in the guidelines, only equipment within the DDAC was considered. Further data about each site, including the number of theatre suites, satellite anaesthetic areas, use of capnography and categories of patients treated (adult, obstetric and paediatric) were collected. An adult DDAC was found at 92% of all sites, but none of the sites had all the essential equipment listed in the ANZCA guidelines. There was limited provision of adult difficult airway equipment within private sites compared to public, and less provision of paediatric difficult airway equipment across all sites treating paediatric patients in metropolitan Perth. Capnography was available in 76% of post anaesthesia care units and used regularly in 27%. Adherence to the ANZCA guidelines regarding the DDAC could be improved. Standardised equipment across a metropolitan region would be of value in the management of the difficult airway. PMID:25233181

  4. 14 CFR 121.345 - Radio equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Radio equipment. 121.345 Section 121.345..., FLAG, AND SUPPLEMENTAL OPERATIONS Instrument and Equipment Requirements § 121.345 Radio equipment. (a) No person may operate an airplane unless it is equipped with radio equipment required for the kind...

  5. 40 CFR 65.103 - Equipment identification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) CONSOLIDATED FEDERAL AIR RULE Equipment Leaks § 65.103 Equipment identification. (a) General... leak is detected. (ii) The owner or operator of equipment designated as difficult-to-monitor according... procedures in § 65.105 if a leak is detected. (d) Special equipment designations: Equipment that is unsafe...

  6. 40 CFR 65.103 - Equipment identification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) CONSOLIDATED FEDERAL AIR RULE Equipment Leaks § 65.103 Equipment identification. (a) General... leak is detected. (ii) The owner or operator of equipment designated as difficult-to-monitor according... procedures in § 65.105 if a leak is detected. (d) Special equipment designations: Equipment that is unsafe...

  7. 40 CFR 65.103 - Equipment identification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) CONSOLIDATED FEDERAL AIR RULE Equipment Leaks § 65.103 Equipment identification. (a) General... leak is detected. (ii) The owner or operator of equipment designated as difficult-to-monitor according... procedures in § 65.105 if a leak is detected. (d) Special equipment designations: Equipment that is unsafe...

  8. Equipment Efficiency for Healthy School Meals. [Videotape].

    ERIC Educational Resources Information Center

    National Food Service Management Inst., University, MS.

    A satellite seminar on large-scale food production equipment discusses ways child nutrition personnel can maximize use of existing equipment, considers research related to use of existing equipment, explains plan reviews for equipment selection and purchase, and explores new equipment options. Examples illustrate use of planning or modernizing…

  9. 1968 Listing of Swimming Pool Equipment.

    ERIC Educational Resources Information Center

    National Sanitation Foundation, Ann Arbor, MI. Testing Lab.

    An up-to-date listing of swimming pool equipment including--(1) companies authorized to display the National Sanitation Foundation seal of approval, (2) equipment listed as meeting NSF swimming pool equipment standards relating to diatomite type filters, (3) equipment listed as meeting NSF swimming pool equipment standard relating to sand type…

  10. 14 CFR 121.345 - Radio equipment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Radio equipment. 121.345 Section 121.345..., FLAG, AND SUPPLEMENTAL OPERATIONS Instrument and Equipment Requirements § 121.345 Radio equipment. (a) No person may operate an airplane unless it is equipped with radio equipment required for the kind...

  11. 14 CFR 121.345 - Radio equipment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Radio equipment. 121.345 Section 121.345..., FLAG, AND SUPPLEMENTAL OPERATIONS Instrument and Equipment Requirements § 121.345 Radio equipment. (a) No person may operate an airplane unless it is equipped with radio equipment required for the kind...

  12. 14 CFR 121.345 - Radio equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Radio equipment. 121.345 Section 121.345..., FLAG, AND SUPPLEMENTAL OPERATIONS Instrument and Equipment Requirements § 121.345 Radio equipment. (a) No person may operate an airplane unless it is equipped with radio equipment required for the kind...

  13. Hyperbaric intensive care technology and equipment.

    PubMed

    Millar, Ian L

    2015-03-01

    In an emergency, life support can be provided during recompression or hyperbaric oxygen therapy using very basic equipment, provided the equipment is hyperbaric-compatible and the clinicians have appropriate experience. For hyperbaric critical care to be provided safely on a routine basis, however, a great deal of preparation and specific equipment is needed, and relatively few facilities have optimal capabilities at present. The type, size and location of the chamber are very influential factors. Although monoplace chamber critical care is possible, it involves special adaptations and inherent limitations that make it inappropriate for all but specifically experienced teams. A large, purpose-designed chamber co-located with an intensive care unit is ideal. Keeping the critically ill patient on their normal bed significantly improves quality of care where this is possible. The latest hyperbaric ventilators have resolved many of the issues normally associated with hyperbaric ventilation, but at significant cost. Multi-parameter monitoring is relatively simple with advanced portable monitors, or preferably installed units that are of the same type as used elsewhere in the hospital. Whilst end-tidal CO₂ readings are changed by pressure and require interpretation, most other parameters display normally. All normal infusions can be continued, with several examples of syringe drivers and infusion pumps shown to function essentially normally at pressure. Techniques exist for continuous suction drainage and most other aspects of standard critical care. At present, the most complex life support technologies such as haemofiltration, cardiac assist devices and extra-corporeal membrane oxygenation remain incompatible with the hyperbaric environment. PMID:25964040

  14. Hyperbaric intensive care technology and equipment.

    PubMed

    Millar, Ian L

    2015-03-01

    In an emergency, life support can be provided during recompression or hyperbaric oxygen therapy using very basic equipment, provided the equipment is hyperbaric-compatible and the clinicians have appropriate experience. For hyperbaric critical care to be provided safely on a routine basis, however, a great deal of preparation and specific equipment is needed, and relatively few facilities have optimal capabilities at present. The type, size and location of the chamber are very influential factors. Although monoplace chamber critical care is possible, it involves special adaptations and inherent limitations that make it inappropriate for all but specifically experienced teams. A large, purpose-designed chamber co-located with an intensive care unit is ideal. Keeping the critically ill patient on their normal bed significantly improves quality of care where this is possible. The latest hyperbaric ventilators have resolved many of the issues normally associated with hyperbaric ventilation, but at significant cost. Multi-parameter monitoring is relatively simple with advanced portable monitors, or preferably installed units that are of the same type as used elsewhere in the hospital. Whilst end-tidal CO₂ readings are changed by pressure and require interpretation, most other parameters display normally. All normal infusions can be continued, with several examples of syringe drivers and infusion pumps shown to function essentially normally at pressure. Techniques exist for continuous suction drainage and most other aspects of standard critical care. At present, the most complex life support technologies such as haemofiltration, cardiac assist devices and extra-corporeal membrane oxygenation remain incompatible with the hyperbaric environment.

  15. Personal protective equipment and decontamination of adults and children.

    PubMed

    Holland, Michael G; Cawthon, David

    2015-02-01

    Accurate identification of the hazardous material is essential for proper care. Efficient hospital security and triage must prevent contaminated victims from entering the emergency department (ED) and causing secondary contamination. The decontamination area should be located outside the ambulance entrance. Decontamination priorities are protection of the health care worker, utilization of Level C personal protective equipment, and proper decontamination of the exposed patient. Decontamination proceeds in a head-to-toe sequence. Run-off water is a hazardous waste. Hospital and Community Management Planning for these emergencies is essential for proper preparation and effective response to the hazardous materials incident.

  16. Personal protective equipment and decontamination of adults and children.

    PubMed

    Holland, Michael G; Cawthon, David

    2015-02-01

    Accurate identification of the hazardous material is essential for proper care. Efficient hospital security and triage must prevent contaminated victims from entering the emergency department (ED) and causing secondary contamination. The decontamination area should be located outside the ambulance entrance. Decontamination priorities are protection of the health care worker, utilization of Level C personal protective equipment, and proper decontamination of the exposed patient. Decontamination proceeds in a head-to-toe sequence. Run-off water is a hazardous waste. Hospital and Community Management Planning for these emergencies is essential for proper preparation and effective response to the hazardous materials incident. PMID:25455662

  17. Automatic stabilization

    NASA Technical Reports Server (NTRS)

    Haus, FR

    1936-01-01

    This report concerns the study of automatic stabilizers and extends it to include the control of the three-control system of the airplane instead of just altitude control. Some of the topics discussed include lateral disturbed motion, static stability, the mathematical theory of lateral motion, and large angles of incidence. Various mechanisms and stabilizers are also discussed. The feeding of Diesel engines by injection pumps actuated by engine compression, achieves the required high speeds of injection readily and permits rigorous control of the combustible charge introduced into each cylinder and of the peak pressure in the resultant cycle.

  18. Vehicle dynamic stability and rollover

    NASA Astrophysics Data System (ADS)

    Allen, R. W.; Szostak, H. T.; Klyde, D. H.; Rosenthal, T. J.; Owens, K. J.

    1992-06-01

    The report considers ground vehicle lateral/directional stability which is of primary concern in traffic safety. Lateral/directional dynamics involve yawing, rolling, and lateral acceleration motions, and stability concerns include spinout and rollover. The report describes accident analysis, vehicle testing, and computer simulation analysis designed to give insight into basic vehicle design variables that contribute to stability problems. The results of vehicle testing and simulation analysis indicate that a vehicle that has both a relatively low ratio of track width to center of gravity height and is equipped with tires which have a relatively high peak coefficient of friction will have a propensity to rollover during steering maneuvers on a flat surface. Vehicle testing and computer simulation analysis also indicate that directional stability is significantly influenced by the relationship between vehicle weight distribution and lateral load transfer distribution that is greater than or equal to the percent weight on the front axle.

  19. Medical equipment leasing. Benefits and opportunities.

    PubMed

    Hill, R

    1995-03-01

    Medical equipment manufacturers throughout Europe now have the opportunity to take advantage of changes in the United Kingdom Treasury rules, which introduce flexibility into hospital financing. This could result in more equipment sales for manufacturers and better equipped hospitals.

  20. 34 CFR 300.14 - Equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... DISABILITIES General Definitions Used in This Part § 300.14 Equipment. Equipment means— (a) Machinery, utilities, and built-in equipment, and any necessary enclosures or structures to house the...

  1. 34 CFR 300.14 - Equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... DISABILITIES General Definitions Used in This Part § 300.14 Equipment. Equipment means— (a) Machinery, utilities, and built-in equipment, and any necessary enclosures or structures to house the...

  2. Discovery of essential fatty acids

    PubMed Central

    Spector, Arthur A.; Kim, Hee-Yong

    2015-01-01

    Dietary fat was recognized as a good source of energy and fat-soluble vitamins by the first part of the 20th century, but fatty acids were not considered to be essential nutrients because they could be synthesized from dietary carbohydrate. This well-established view was challenged in 1929 by George and Mildred Burr who reported that dietary fatty acid was required to prevent a deficiency disease that occurred in rats fed a fat-free diet. They concluded that fatty acids were essential nutrients and showed that linoleic acid prevented the disease and is an essential fatty acid. The Burrs surmised that other unsaturated fatty acids were essential and subsequently demonstrated that linolenic acid, the omega-3 fatty acid analog of linoleic acid, is also an essential fatty acid. The discovery of essential fatty acids was a paradigm-changing finding, and it is now considered to be one of the landmark discoveries in lipid research. PMID:25339684

  3. Essential Medicines: An Indian Perspective

    PubMed Central

    Maiti, Rituparna; Bhatia, Vikas; Padhy, Biswa Mohan; Hota, Debasish

    2015-01-01

    The concept of defining essential medicines and establishing a list of them was aimed to improve the availability of affordable medicines for the world's poor. Access to essential medicines is a major determinant of health outcomes. Several countries have made substantial progress towards increasing access to essential medicines, but access to essential medicines in developing countries like India is not adequate. In this review we have tried to present the Indian scenario in respect to availability and accessibility of essential medicines over last one decade. To enhance the credibility of Indian healthcare system, procurement and delivery systems of essential medicines have to be strengthened through government commitment, careful selection, adequate public sector financing, efficient distribution systems, control on taxes and duties, and inculcating a culture of rational use of medicines in current and future prescribers. PMID:26435594

  4. Essential Medicines: An Indian Perspective.

    PubMed

    Maiti, Rituparna; Bhatia, Vikas; Padhy, Biswa Mohan; Hota, Debasish

    2015-01-01

    The concept of defining essential medicines and establishing a list of them was aimed to improve the availability of affordable medicines for the world's poor. Access to essential medicines is a major determinant of health outcomes. Several countries have made substantial progress towards increasing access to essential medicines, but access to essential medicines in developing countries like India is not adequate. In this review we have tried to present the Indian scenario in respect to availability and accessibility of essential medicines over last one decade. To enhance the credibility of Indian healthcare system, procurement and delivery systems of essential medicines have to be strengthened through government commitment, careful selection, adequate public sector financing, efficient distribution systems, control on taxes and duties, and inculcating a culture of rational use of medicines in current and future prescribers. PMID:26435594

  5. Membrane stabilizer

    DOEpatents

    Mingenbach, W.A.

    1988-02-09

    A device is provided for stabilizing a flexible membrane secured within a frame, wherein a plurality of elongated arms are disposed radially from a central hub which penetrates the membrane, said arms imposing alternately against opposite sides of the membrane, thus warping and tensioning the membrane into a condition of improved stability. The membrane may be an opaque or translucent sheet or other material. 10 figs.

  6. Stabilizing Microwave Frequency of a Photonic Oscillator

    NASA Technical Reports Server (NTRS)

    Maleki, Lute; Yu, Nan; Tu, Meirong

    2006-01-01

    A scheme for stabilizing the frequency of a microwave signal is proposed that exploits the operational characteristics of a coupled optoelectronic oscillator (COEO) and related optoelectronic equipment. An essential element in the scheme is a fiber mode-locked laser (MLL), the optical frequency of which is locked to an atomic transition. In this scheme, the optical frequency stability of the mode-locked laser is transferred to that of the microwave in the same device. Relative to prior schemes for using wideband optical frequency comb to stabilize microwave signals, this scheme is simpler and lends itself more readily to implementation in relatively compact, rugged equipment. The anticipated development of small, low-power, lightweight, highly stable microwave oscillators based on this scheme would afford great benefits in communication, navigation, metrology, and fundamental sciences. COEOs of various designs, at various stages of development, in some cases called by different names, have been described in a number of prior NASA Tech Briefs articles. A COEO is an optoelectronic apparatus that generates both short (picosecond) optical pulses and a steady microwave signal having an ultrahigh degree of spectral purity. The term "coupled optoelectronic" in the full name of such an apparatus signifies that its optical and electronic oscillations are coupled to each other in a single device. The present frequency-stabilization scheme is best described indirectly by describing the laboratory apparatus used to demonstrate it. The apparatus (see figure) includes a COEO that generates a comb-like optical spectrum, the various frequency components of which interfere, producing short optical pulses. This spectrum is centered at a nominal wavelength of 1,560 nm. The spectrum separation of this comb is about 10 GHz, as determined primarily by the length of an optical loop and the bandpass filter in the microwave feedback loop. The optical loop serves as microwave resonator

  7. Subterranean heat exchanger for refrigeration air conditioning equipment

    SciTech Connect

    Rothwell, H.

    1980-09-30

    Heat exchanger apparatus for use with refrigeration cycle heating and cooling equipment is disclosed. In the preferred embodiment, it cooperates with and modifies refrigeration equipment including a compressor, an expansion valve, an evaporator coil and a closed loop for cycling refrigerant. This apparatus is a sealed container adapted to be placed in a well extending into artesian (Relatively heated or chilled) formations whereby the water of the formation stabilizes the temperature around the unit and enables heating and cooling. The sealed unit receives refrigerant from the top which flows along the sidewall at a reduced temperature, thereby condensing on the sidewall and trickling down the sidewall to collect in a sump at the bottom where the compressor pump picks up condensed refrigerant as a liquid and pumps it out of the artesian well to the connected refrigeration equipment.

  8. Analyzing the dynamic behavior of downhole equipment during drilling

    SciTech Connect

    Baird, J.A.; Caskey, B.C.

    1984-01-01

    Advanced geothermal drilling systems will require a bottom hole assembly (BHA) which utilizes sophisticated electronic and mechanical equipment to accomplish faster, more trouble free, smarter drilling. The bit-drill string/formation interaction during drilling imposes complex, intermittent dynamic loading on the downhole equipment. A finite element computer code, GEODYN, is being developed to allow analysis of the structural response of the downhole equipment during drilling and to simulate the drilling phenomena (i.e. penetration, direction, etc.). Phase 1 GEODYN, completed early in 1984, provides the capability to model the dynamic response of a polycrystalline diamond compact (PDC) bit interacting with a non-homogeneous formation. Succeeding development phases will allow inclusion of stabilizers and, eventually, the entire drill string in addition to facilitating drill ahead simulation.

  9. Remote welding equipment for TPX

    SciTech Connect

    Silke, G.W.; Junge, R.

    1995-12-31

    Remote welding equipment and techniques are necessary for maintenance of the Tokamak Physics Experiment (TPX) Plasma Facing Components (PFCs). The processes identified for this application includes inside diameter (i.d.) and outside diameter (o.d.) Gas Tungsten Arc (GTA) welding of titanium and stainless steel alloys. Welding equipment developed for this application includes some unique features due to the specialized environment of the TPX vessel. Remote features of this equipment must include the ability to acquire and align the parts being welded, perform all welding operations and visually inspect the weld area. Designs for weld heads require the integration of industry proven hardware with the special features include compact size, remote manipulation, remote clamping and alignment, remote vision, full inert gas coverage, arc voltage control, wire feed, programmable weld schedules and failure recovery.

  10. Power Product Equipment Technician: Construction Equipment. Teacher Edition. Student Edition.

    ERIC Educational Resources Information Center

    Hilley, Robert

    The instructor's guide in this package, which is one in a series of new publications developed to replace the Multistate Academic and Vocational Curriculum Consortium's previous small-engine curricula, contains the materials required to teach a competency-based course in repairing construction equipment. The guide begins with an introduction…

  11. Equipping the Open-Plan School, Equipping for Open Education.

    ERIC Educational Resources Information Center

    Lassiter, Frank

    The performance specifications of furniture and equipment for open education and open-plan schools differ from conventional classroom furniture in that it must be easily moved, have a range of dimensions, contain multipurpose interchangeable components, and be designed to accommodate a variety of student/teacher uses. The author suggests some…

  12. Astronaut Alan Bean flies the Astronaut Maneuvering Equipment

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Astronaut Alan L. Bean, Skylab 3 commander, flies the M509 Astronaut Maneuvering Equipment in the foreward dome area of the Orbital Workshop (OWS) on the space station cluster in Earth orbit. Bean is strapped in to the back-mounted, hand-controlled Automatically Stabilized Maneuvering Unit (ASMU). This ASMU exerperiment is being done in shirt sleeves. The dome area where the experiment is conducted is about 22 feet in diameter and 19 feet from top to bottom.

  13. Astronaut Alan Bean flies the Astronaut Maneuvering Equipment

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Astronaut Alan L. Bean, Skylab 3 commander, flies the M509 Astronaut Maneuvering Equipment in the forward dome area of the Orbital Workshop (OWS) on the space station cluster in Earth orbit. Bean is strapped in to the back-mounted, hand-controlled Automatically Stabilized Maneuvering Unit (ASMU). This ASMU exerperiment is being done in shirt sleeves. The dome area where the experiment is conducted is about 22 feet in diameter and 19 feet from top to bottom.

  14. System design description PFP thermal stabilization

    SciTech Connect

    RISENMAY, H.R.

    1998-11-10

    The purpose of this document is to provide a system design description and design basis for the Plutonium Finishing P1ant (PFP) Thermal Stabilization project. The sources of material for this project are residues scraped from glovebox floors and materials already stored in vault storage that need further stabilizing to meet the 3013 storage requirements. Stabilizing this material will promote long term storage and reduced worker exposure. This document addresses: function design, equipment, and safety requirements for thermal stabilization of plutonium residues and oxides.

  15. Leasing equipment minimizes capital investment.

    PubMed

    Zimmerman, M E; Maier, R A

    1989-03-01

    As consumers continue to demand the most advanced technology at the lowest cost, healthcare organizations are turning to leasing as a way of acquiring equipment with a minimum amount of capital investment. Institutions considering leasing should determine their balance sheet constraints, compare the relative costs of debt financing and leasing, and assess the residual value of the equipment at the end of its use. Comparing potential lessors requires careful analysis of rate structures and the capability of the companies to commit to a contract promptly.

  16. Advanced deep sea diving equipment

    NASA Technical Reports Server (NTRS)

    Danesi, W. A.

    1972-01-01

    Design requirements are generated for a deep sea heavy duty diving system to equip salvage divers with equipment and tools that permit work of the same quality and in times approaching that done on the surface. The system consists of a helmet, a recirculator for removing carbon dioxide, and the diver's dress. The diver controls the inlet flow by the recirculatory control valve and is able to change closed cycle operation to open cycle if malfunction occurs. Proper function of the scrubber in the recirculator minimizes temperature and humidity effects as it filters the returning air.

  17. Shuttle extravehicular life support equipment

    NASA Technical Reports Server (NTRS)

    Sutton, J. G.

    1973-01-01

    A Shuttle EVA/IVA Requirements Study was conducted by Hamilton Standard for NASA. The objectives of this study were to establish a baseline EVA approach for Shuttle and to prepare requirements for the EVA equipment required to support these operations. This paper presents the results of the EVA life support requirements definition effort and defines candidate configurations which meet these requirements. Various subsystem and system concepts were identified and evaluated to determine the most desirable approaches. Both independent and umbilical configurations are considered. Because certain EVA missions could involve contamination-sensitive payloads, the impact of integrating noncontaminating equipment is also considered.

  18. Trends in powder processing equipment

    SciTech Connect

    Sheppard, L.M.

    1993-05-01

    Spray drying is the most widely used process for producing particles. It is used in industries other than ceramics including food, chemicals, and pharmaceutical. The process involves the atomization of a liquid feed stock into a spray of droplets and contacting the droplets with hot air in a drying chamber. The sprays are produced by either rotary or nozzle atomizers. Evaporation of moisture from the droplets and formation of dry particles proceed under controlled temperature and airflow conditions. Powder is then discharged continuously from the drying chamber. Spray drying equipment is being improved to handle an ever-increasing number of applications. Several developments in particle-size reduction equipment are also described.

  19. RTI Essential Components Integrity Worksheet

    ERIC Educational Resources Information Center

    National Center on Response to Intervention, 2011

    2011-01-01

    The Response to Intervention (RTI) Essential Components Integrity Rubric and the RTI Essential Components Integrity Worksheet are for use by individuals responsible for monitoring the school-level fidelity of Response to Intervention (RTI) implementation. They may also be used by schools for self-appraisal; however, they were not designed for…

  20. Essentialism: Common Sense Quality Improvement.

    ERIC Educational Resources Information Center

    Wallin, Desna L.; Ryan, John R.

    Essentialism is a trimmed down, action-oriented, user-friendly approach to Total Quality Management (TQM) in education. This book explores the concept of essentialism to describe strategies for implementing TQM in community colleges. Chapter 1 examines the history of the TQM movement and reviews experiences of community college practitioners…

  1. RTI Essential Components Integrity Rubric

    ERIC Educational Resources Information Center

    National Center on Response to Intervention, 2011

    2011-01-01

    The Response to Intervention (RTI) Essential Components Integrity Rubric is for use by individuals who are responsible for monitoring school-level fidelity of RTI implementation. The rubric is aligned with "Essential Components of RTI: A Closer Look at Response to Intervention" (National Center on Response to Intervention, 2010). Subjects covered…

  2. A novel vertebral stabilization method for producing contusive spinal cord injury.

    PubMed

    Walker, Melissa J; Walker, Chandler L; Zhang, Y Ping; Shields, Lisa B E; Shields, Christopher B; Xu, Xiao-Ming

    2015-01-01

    Clinically-relevant animal cervical spinal cord injury (SCI) models are essential for developing and testing potential therapies; however, producing reliable cervical SCI is difficult due to lack of satisfactory methods of vertebral stabilization. The conventional method to stabilize the spine is to suspend the rostral and caudal cervical spine via clamps attached to cervical spinous processes.  However, this method of stabilization fails to prevent tissue yielding during the contusion as the cervical spinal processes are too short to be effectively secured by the clamps (Figure 1).  Here we introduce a new method to completely stabilize the cervical vertebra at the same level of the impact injury.  This method effectively minimizes movement of the spinal column at the site of impact, which greatly improves the production of consistent SCIs.  We provide visual description of the equipment (Figure 2-4), methods, and a step-by-step protocol for the stabilization of the cervical 5 vertebra (C5) of adult rats, to perform laminectomy (Figure 5) and produce a contusive SCI thereafter.  Although we only demonstrate a cervical hemi-contusion using the NYU/MASCIS impactor device, this vertebral stabilization technique can be applied to other regions of the spinal cord, or be adapted to other SCI devices.  Improving spinal cord exposure and fixation through vertebral stabilization may be valuable for producing consistent and reliable injuries to the spinal cord.  This vertebral stabilization method can also be used for stereotactic injections of cells and tracers, and for imaging using two-photon microscopy in various neurobiological studies. PMID:25590284

  3. A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury

    PubMed Central

    Zhang, Y. Ping; Shields, Lisa B. E.; Shields, Christopher B.; Xu, Xiao-Ming

    2015-01-01

    Clinically-relevant animal cervical spinal cord injury (SCI) models are essential for developing and testing potential therapies; however, producing reliable cervical SCI is difficult due to lack of satisfactory methods of vertebral stabilization. The conventional method to stabilize the spine is to suspend the rostral and caudal cervical spine via clamps attached to cervical spinous processes.  However, this method of stabilization fails to prevent tissue yielding during the contusion as the cervical spinal processes are too short to be effectively secured by the clamps (Figure 1).  Here we introduce a new method to completely stabilize the cervical vertebra at the same level of the impact injury.  This method effectively minimizes movement of the spinal column at the site of impact, which greatly improves the production of consistent SCIs.  We provide visual description of the equipment (Figure 2-4), methods, and a step-by-step protocol for the stabilization of the cervical 5 vertebra (C5) of adult rats, to perform laminectomy (Figure 5) and produce a contusive SCI thereafter.  Although we only demonstrate a cervical hemi-contusion using the NYU/MASCIS impactor device, this vertebral stabilization technique can be applied to other regions of the spinal cord, or be adapted to other SCI devices.  Improving spinal cord exposure and fixation through vertebral stabilization may be valuable for producing consistent and reliable injuries to the spinal cord.  This vertebral stabilization method can also be used for stereotactic injections of cells and tracers, and for imaging using two-photon microscopy in various neurobiological studies. PMID:25590284

  4. Preparation and characterization of clove essential oil-loaded liposomes.

    PubMed

    Sebaaly, Carine; Jraij, Alia; Fessi, Hatem; Charcosset, Catherine; Greige-Gerges, Hélène

    2015-07-01

    In this study, suitable formulations of natural soybean phospholipid vesicles were developed to improve the stability of clove essential oil and its main component, eugenol. Using an ethanol injection method, saturated (Phospholipon 80H, Phospholipon 90H) and unsaturated soybean (Lipoid S100) phospholipids, in combination with cholesterol, were used to prepare liposomes at various eugenol and clove essential oil concentrations. Liposomal batches were characterized and compared for their size, polydispersity index, Zeta potential, loading rate, encapsulation efficiency and morphology. The liposomes were tested for their stability after storing them for 2 months at 4°C by monitoring changes in their mean size, polydispersity index and encapsulation efficiency (EE) values. It was found that liposomes exhibited nanometric oligolamellar and spherical shaped vesicles and protected eugenol from degradation induced by UV exposure; they also maintained the DPPH-scavenging activity of free eugenol. Liposomes constitute a suitable system for encapsulation of volatile unstable essential oil constituents. PMID:25704683

  5. Equipment

    ERIC Educational Resources Information Center

    Education in Chemistry, 1976

    1976-01-01

    Described are a number of publications and items for use in chemistry. Included are brief descriptions of actuators, thermometer strips, current balances, and a variety of catalogues and other publications. (RH)

  6. Heating and Cooling Equipment Selection

    SciTech Connect

    Not Available

    2002-01-01

    This is one of a series of technology fact sheets created to help housing designers and builders adopt a whole-house design approach and energy efficient design practices. The fact sheet helps people choose the correct equipment for heating and cooling to reduce initial costs, increase homeowner comfort, increase operating efficiency, and greatly reduce utility costs.

  7. Lawn and Garden Equipment Repair.

    ERIC Educational Resources Information Center

    Hardway, Jack; And Others

    This publication is designed to supplement the Comprehensive Small Engine Rapair guide by covering in detail all aspects of lawn and garden equipment repair not included in general engine repair or the repair of other small engines. It consists of instructional materials for both teachers and students, written in terms of student performance using…

  8. Strategy Guideline. HVAC Equipment Sizing

    SciTech Connect

    Burdick, Arlan

    2012-02-01

    This guide describes the equipment selection of a split system air conditioner and furnace for an example house in Chicago, IL as well as a heat pump system for an example house in Orlando, FL. The required heating and cooling load information for the two example houses was developed in the Department of Energy Building America Strategy Guideline: Accurate Heating and Cooling Load Calculations.

  9. Multimedia Equipment for Distance Education.

    ERIC Educational Resources Information Center

    Schiller, Scott S.

    1993-01-01

    Discusses the use of multimedia equipment for distance education. Topics addressed include use of the Internet; distance learning for educators; and cable television and/or fiber optics, including interactive television and satellite technology. A sidebar lists online and telecommunications providers. (LRW)

  10. Computer Equipment Repair Curriculum Guide.

    ERIC Educational Resources Information Center

    Reneau, Fred; And Others

    This guide is intended for use in a course to train students to repair computer equipment and perform related administrative and customer service tasks. Addressed in the individual units are the following topics (with selected subtopics in brackets): performing administrative functions (preparing service bills, maintaining accounts and labor…

  11. Modern refining and petrochemical equipment

    SciTech Connect

    Pugach, V.V.

    1995-07-01

    Petroleum refining and petroleum chemistry are characterized by a whole set of manufacturing processes and methods, whose application depends on the initial raw material and the final products. Therefore, refining and petrochemical equipment has many different operational principles, design solutions, and materials. The activities of the Russian Petroleum Industry are discussed.

  12. Using Gaming Equipment to Teach

    ERIC Educational Resources Information Center

    Curriculum Review, 2009

    2009-01-01

    Gaming equipment (such as Nintendo's Wii[TM]) is making its way to schools and classrooms. However, most of the discussion regarding how to use this technology and integrate it into lesson plans is happening in blogs on the Internet. An advocate of interactive media in the classroom, Dr. Dawn Hawkins, a faculty member for the Art Institute of…

  13. Business Classroom and Laboratory Equipment.

    ERIC Educational Resources Information Center

    Jorgensen, Carl E.; Campbell, Melvin E.

    1983-01-01

    This catalog, intended to enable business educators to furnish classrooms and laboratories for business and office education, lists appropriate equipment, office furniture, and specialty items. Each category identifies vendors' names and addresses and describes their product lines and price ranges. (SK)

  14. Housing, Home Furnishings, and Equipment.

    ERIC Educational Resources Information Center

    Texas Tech Univ., Lubbock. Home Economics Curriculum Center.

    Designed for use in consumer and homemaking education in Texas, this curriculum guide is on the subject of housing, home furnishings, and equipment. An introduction to the guide, covering its use and program and curriculum planning, provides a list of suggested readings. Information on teaching handicapped and disadvantaged students follows. The…

  15. Preventive Maintenance Handbook. Audiovisual Equipment.

    ERIC Educational Resources Information Center

    Educational Products Information Exchange Inst., Stony Brook, NY.

    The preventive maintenance system for audiovisual equipment presented in this handbook is designed by specialists so that it can be used by nonspecialists in school sites. The report offers specific advice on saftey factors and also lists major problems that should not be handled by nonspecialists. Other aspects of a preventive maintenance system…

  16. Is Equipment Management Really Neccessary

    NASA Technical Reports Server (NTRS)

    Tavernier, James P.

    1996-01-01

    This workshop is designed to foster an initiative for intelligent Equipment Management employing the advances in information systems and opportunities uncovered by the reengineering process. The guiding concept behind the initiative is that both contributions and benefits must be equitable and balanced for all participants.

  17. 14 CFR 25.1431 - Electronic equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Electronic equipment. 25.1431 Section 25... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Miscellaneous Equipment § 25.1431 Electronic equipment. (a) In showing compliance with § 25.1309 (a) and (b) with respect to radio and...

  18. 14 CFR 23.1431 - Electronic equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Electronic equipment. 23.1431 Section 23... Equipment § 23.1431 Electronic equipment. (a) In showing compliance with § 23.1309(b)(1) and (2) with respect to radio and electronic equipment and their installations, critical environmental conditions...

  19. 14 CFR 23.1431 - Electronic equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Electronic equipment. 23.1431 Section 23... Equipment § 23.1431 Electronic equipment. (a) In showing compliance with § 23.1309(b)(1) and (2) with respect to radio and electronic equipment and their installations, critical environmental conditions...

  20. 14 CFR 25.1431 - Electronic equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Electronic equipment. 25.1431 Section 25... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Equipment Miscellaneous Equipment § 25.1431 Electronic equipment. (a) In showing compliance with § 25.1309 (a) and (b) with respect to radio and...

  1. 14 CFR 23.1561 - Safety equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Safety equipment. 23.1561 Section 23.1561... Markings and Placards § 23.1561 Safety equipment. (a) Safety equipment must be plainly marked as to method of operation. (b) Stowage provisions for required safety equipment must be marked for the benefit...

  2. 14 CFR 23.1561 - Safety equipment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Safety equipment. 23.1561 Section 23.1561... Markings and Placards § 23.1561 Safety equipment. (a) Safety equipment must be plainly marked as to method of operation. (b) Stowage provisions for required safety equipment must be marked for the benefit...

  3. 14 CFR 23.1561 - Safety equipment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Safety equipment. 23.1561 Section 23.1561... Markings and Placards § 23.1561 Safety equipment. (a) Safety equipment must be plainly marked as to method of operation. (b) Stowage provisions for required safety equipment must be marked for the benefit...

  4. 14 CFR 23.1561 - Safety equipment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Safety equipment. 23.1561 Section 23.1561... Markings and Placards § 23.1561 Safety equipment. (a) Safety equipment must be plainly marked as to method of operation. (b) Stowage provisions for required safety equipment must be marked for the benefit...

  5. 14 CFR 23.1561 - Safety equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Safety equipment. 23.1561 Section 23.1561... Markings and Placards § 23.1561 Safety equipment. (a) Safety equipment must be plainly marked as to method of operation. (b) Stowage provisions for required safety equipment must be marked for the benefit...

  6. 23 CFR 140.910 - Equipment.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Equipment. 140.910 Section 140.910 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Railroad Work § 140.910 Equipment. (a) Company owned equipment. Cost of company-owned equipment may...

  7. 23 CFR 140.910 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Equipment. 140.910 Section 140.910 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Railroad Work § 140.910 Equipment. (a) Company owned equipment. Cost of company-owned equipment may...

  8. 23 CFR 140.910 - Equipment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Equipment. 140.910 Section 140.910 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Railroad Work § 140.910 Equipment. (a) Company owned equipment. Cost of company-owned equipment may...

  9. 23 CFR 140.910 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Equipment. 140.910 Section 140.910 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Railroad Work § 140.910 Equipment. (a) Company owned equipment. Cost of company-owned equipment may...

  10. 23 CFR 140.910 - Equipment.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Equipment. 140.910 Section 140.910 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Railroad Work § 140.910 Equipment. (a) Company owned equipment. Cost of company-owned equipment may...

  11. 46 CFR 197.460 - Diving equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Diving equipment. 197.460 Section 197.460 Shipping COAST... GENERAL PROVISIONS Commercial Diving Operations Periodic Tests and Inspections of Diving Equipment § 197.460 Diving equipment. The diving supervisor shall insure that the diving equipment designated for...

  12. 46 CFR 197.460 - Diving equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Diving equipment. 197.460 Section 197.460 Shipping COAST... GENERAL PROVISIONS Commercial Diving Operations Periodic Tests and Inspections of Diving Equipment § 197.460 Diving equipment. The diving supervisor shall insure that the diving equipment designated for...

  13. 7 CFR 58.626 - Packaging equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Packaging equipment. 58.626 Section 58.626 Agriculture....626 Packaging equipment. Packaging equipment designed to mechanically fill and close single service... Standards for Equipment for Packaging Frozen Desserts and Cottage Cheese. Quality Specifications for...

  14. 47 CFR 54.635 - Eligible equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... equipment. (a) Both individual and consortium applicants may receive support for network equipment necessary...) Consortium applicants may also receive support for network equipment necessary to manage, control, or maintain an eligible service or a dedicated health care broadband network. Support for network equipment...

  15. 49 CFR 195.430 - Firefighting equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 3 2014-10-01 2014-10-01 false Firefighting equipment. 195.430 Section 195.430... PIPELINE Operation and Maintenance § 195.430 Firefighting equipment. Each operator shall maintain adequate firefighting equipment at each pump station and breakout tank area. The equipment must be— (a) In...

  16. 49 CFR 195.430 - Firefighting equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 3 2013-10-01 2013-10-01 false Firefighting equipment. 195.430 Section 195.430... PIPELINE Operation and Maintenance § 195.430 Firefighting equipment. Each operator shall maintain adequate firefighting equipment at each pump station and breakout tank area. The equipment must be— (a) In...

  17. 49 CFR 195.430 - Firefighting equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Firefighting equipment. 195.430 Section 195.430... PIPELINE Operation and Maintenance § 195.430 Firefighting equipment. Each operator shall maintain adequate firefighting equipment at each pump station and breakout tank area. The equipment must be— (a) In...

  18. 49 CFR 195.430 - Firefighting equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Firefighting equipment. 195.430 Section 195.430... PIPELINE Operation and Maintenance § 195.430 Firefighting equipment. Each operator shall maintain adequate firefighting equipment at each pump station and breakout tank area. The equipment must be— (a) In...

  19. 49 CFR 195.430 - Firefighting equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 3 2012-10-01 2012-10-01 false Firefighting equipment. 195.430 Section 195.430... PIPELINE Operation and Maintenance § 195.430 Firefighting equipment. Each operator shall maintain adequate firefighting equipment at each pump station and breakout tank area. The equipment must be— (a) In...

  20. 40 CFR 63.1003 - Equipment identification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) National Emission Standards for Equipment Leaks-Control Level 1 § 63.1003 Equipment identification. (a... applicable, and repair of the equipment according to the procedures in § 63.1005 if a leak is detected. (ii... leak is detected. (d) Special equipment designations: Unsafe-to-repair—(1) Designation and...

  1. 40 CFR 63.1003 - Equipment identification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) National Emission Standards for Equipment Leaks-Control Level 1 § 63.1003 Equipment identification. (a... applicable, and repair of the equipment according to the procedures in § 63.1005 if a leak is detected. (ii... leak is detected. (d) Special equipment designations: Unsafe-to-repair—(1) Designation and...

  2. The Cost of Maintaining Educational Communications Equipment.

    ERIC Educational Resources Information Center

    Humphrey, David A.

    Tentative formulas for calculating the cost of maintaining educational communications equipment are proposed. The formulas are based on a survey of campuses of the State University of New York. The survey analyzed the types of equipment to be maintained, types of maintenance, who uses the equipment, who services the equipment, and the cost…

  3. 10 CFR 600.134 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Nonprofit Organizations Post-Award Requirements § 600.134 Equipment. (a) Title to equipment acquired by a... organizations for a fee that is less than private companies charge for equivalent services, unless specifically... management standards for equipment acquired with Federal funds and federally-owned equipment shall...

  4. 40 CFR 792.61 - Equipment design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 31 2010-07-01 2010-07-01 true Equipment design. 792.61 Section 792.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Equipment § 792.61 Equipment design. Equipment used in...

  5. 40 CFR 160.61 - Equipment design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Equipment design. 160.61 Section 160.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD LABORATORY PRACTICE STANDARDS Equipment § 160.61 Equipment design. Equipment used in the...

  6. 21 CFR 58.61 - Equipment design.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Equipment design. 58.61 Section 58.61 Food and... PRACTICE FOR NONCLINICAL LABORATORY STUDIES Equipment § 58.61 Equipment design. Equipment used in the... of appropriate design and adequate capacity to function according to the protocol and shall...

  7. 21 CFR 58.61 - Equipment design.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Equipment design. 58.61 Section 58.61 Food and... PRACTICE FOR NONCLINICAL LABORATORY STUDIES Equipment § 58.61 Equipment design. Equipment used in the... of appropriate design and adequate capacity to function according to the protocol and shall...

  8. 40 CFR 160.61 - Equipment design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Equipment design. 160.61 Section 160... LABORATORY PRACTICE STANDARDS Equipment § 160.61 Equipment design. Equipment used in the generation... appropriate design and adequate capacity to function according to the protocol and shall be suitably...

  9. 40 CFR 792.61 - Equipment design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 32 2011-07-01 2011-07-01 false Equipment design. 792.61 Section 792... (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Equipment § 792.61 Equipment design. Equipment used in the... of appropriate design and adequate capacity to function according to the protocol and shall...

  10. Energy-related laboratory equipment (ERLE) guidelines

    SciTech Connect

    Not Available

    1995-01-01

    This document describes the Used Energy-Related Laboratory Equipment grants, and eligibility and procedures for participation. The document contains tables identifying typical equipment that may be requested, where to review ERLE equipment lists, and where to mail applications, a description of the eligible equipment grants access data system, and a copy of the ERLE grant application and instructions for its completion and submission.

  11. 47 CFR 18.203 - Equipment authorization.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Equipment authorization. 18.203 Section 18.203 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND MEDICAL EQUIPMENT Applications and Authorizations § 18.203 Equipment authorization. (a) Consumer ISM equipment, unless...

  12. 47 CFR 18.203 - Equipment authorization.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Equipment authorization. 18.203 Section 18.203 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND MEDICAL EQUIPMENT Applications and Authorizations § 18.203 Equipment authorization. (a) Consumer ISM equipment, unless...

  13. 47 CFR 18.203 - Equipment authorization.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Equipment authorization. 18.203 Section 18.203 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND MEDICAL EQUIPMENT Applications and Authorizations § 18.203 Equipment authorization. (a) Consumer ISM equipment, unless...

  14. 47 CFR 18.203 - Equipment authorization.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Equipment authorization. 18.203 Section 18.203 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND MEDICAL EQUIPMENT Applications and Authorizations § 18.203 Equipment authorization. (a) Consumer ISM equipment, unless...

  15. 47 CFR 18.203 - Equipment authorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Equipment authorization. 18.203 Section 18.203 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL INDUSTRIAL, SCIENTIFIC, AND MEDICAL EQUIPMENT Applications and Authorizations § 18.203 Equipment authorization. (a) Consumer ISM equipment, unless...

  16. 47 CFR 74.550 - Equipment authorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Equipment authorization. 74.550 Section 74.550... § 74.550 Equipment authorization. Each authorization for aural broadcast STL, ICR, and booster stations shall require the use of equipment which has been certificated or verified. Equipment which has not...

  17. 45 CFR 2543.34 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Equipment. 2543.34 Section 2543.34 Public Welfare... Requirements Property Standards § 2543.34 Equipment. (a) Title to equipment acquired by a recipient with... not use equipment acquired with Federal funds to provide services to non-Federal outside...

  18. 7 CFR 58.626 - Packaging equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Packaging equipment. 58.626 Section 58.626 Agriculture....626 Packaging equipment. Packaging equipment designed to mechanically fill and close single service... Standards for Equipment for Packaging Frozen Desserts and Cottage Cheese. Quality Specifications for...

  19. Neuroimaging essentials in essential tremor: A systematic review

    PubMed Central

    Sharifi, Sarvi; Nederveen, Aart J.; Booij, Jan; van Rootselaar, Anne-Fleur

    2014-01-01

    Background Essential tremor is regarded to be a disease of the central nervous system. Neuroimaging is a rapidly growing field with potential benefits to both diagnostics and research. The exact role of imaging techniques with respect to essential tremor in research and clinical practice is not clear. A systematic review of the different imaging techniques in essential tremor is lacking in the literature. Methods We performed a systematic literature search combining the terms essential tremor and familial tremor with the following keywords: imaging, MRI, VBM, DWI, fMRI, PET and SPECT, both in abbreviated form as well as in full form. We summarize and discuss the quality and the external validity of each study and place the results in the context of existing knowledge regarding the pathophysiology of essential tremor. Results A total of 48 neuroimaging studies met our search criteria, roughly divided into 19 structural and 29 functional and metabolic studies. The quality of the studies varied, especially concerning inclusion criteria. Functional imaging studies indicated cerebellar hyperactivity during rest and during tremor. The studies also pointed to the involvement of the thalamus, the inferior olive and the red nucleus. Structural studies showed less consistent results. Discussion and conclusion Neuroimaging techniques in essential tremor give insight into the pathophysiology of essential tremor indicating the involvement of the cerebellum as the most consistent finding. GABAergic dysfunction might be a major premise in the pathophysiological hypotheses. Inconsistencies between studies can be partly explained by the inclusion of heterogeneous patient groups. Improvement of scientific research requires more stringent inclusion criteria and application of advanced analysis techniques. Also, the use of multimodal neuroimaging techniques is a promising development in movement disorders research. Currently, the role of imaging techniques in essential tremor in daily

  20. Blocks: Essential Equipment for Young Children. A Self Instructing Learning Package.

    ERIC Educational Resources Information Center

    Benish, Jean

    This inservice package for teachers provides a rationale for using blocks to enrich the young child's classroom environment and suggests numerous ways blocks can be used to encourage the physical, intellectual, social and emotional development of young children. A brief delineation of the developmental aspects of the block play stages through…

  1. Technology Demonstration Summary, Chemfix Solidification/Stabilization Process, Clackamas, Oregon

    EPA Science Inventory

    ChemfIx's* patented stabilization/solidification technology was demonstrated at the Portable Equipment Salvage Company (PESC) site in Clackamas, Oregon, as part of the Superfund Innovative Technology Evaluation (SITE) program. The Chemfix process is designed to solidify and sta...

  2. SOLIDIFICATION/STABILIZATION - US ENVIRONMENTAL PROTECTION AGENCY SUPERFUND PROGRAM

    EPA Science Inventory

    This presentation outlines the Superfund program approach to site cleanup, then provides information from actual insitu and exsitu solidification/stabilization remediations to illustrate technology, equipment, field implementation, performance evaluation, cleanup specifications, ...

  3. The doctrinal basis for medical stability operations.

    PubMed

    Baker, Jay B

    2010-01-01

    This article describes possible roles for the military in the health sector during stability operations, which exist primarily when security conditions do not permit the free movement of civilian actors. This article reviews the new U.S. Army Field Manuals (FMs) 3-24, Counterinsurgency and FM 3-07, Stability Operations, in the context of the health sector. Essential tasks in medical stability operations are identified for various logical lines of operation including information operations, civil security, civil control, support to governance, support to economic development, and restoration of essential services. Restoring essential services is addressed in detail including coordination, assessment, actions, and metrics in the health sector. Coordination by the military with other actors in the health sector including host nation medical officials, other United States governmental agencies, international governmental organizations (IGOs), and nongovernment organizations (NGOs) is key to success in medical stability operations. PMID:20108837

  4. Genetics Home Reference: essential tremor

    MedlinePlus

    ... can also occur when the muscles are opposing gravity, such as when the hands are extended. It ... may be linked to essential tremor , but no specific genetic associations have been confirmed. Several genes as ...

  5. Essential Oils, Part I: Introduction.

    PubMed

    de Groot, Anton C; Schmidt, Erich

    2016-01-01

    Essential oils are widely used in the flavor, food, fragrance, and cosmetic industries in many applications. Contact allergy to them is well known and has been described for 80 essential oils. The relevance of positive patch test reactions often remains unknown. Knowledge of the chemical composition of essential oils among dermatologists is suspected to be limited, as such data are published in journals not read by the dermatological community. Therefore, the authors have fully reviewed and published the literature on contact allergy to and chemical composition of essential oils. Selected topics from this publication will be presented in abbreviated form in Dermatitis starting with this issue, including I. Introduction; II. General aspects; III. Chemistry; IV. General aspects of contact allergy; V. Peppermint oil, lavender oil and lemongrass oil; VI: Sandalwood oil, ylang-ylang oil, and jasmine absolute. PMID:26983089

  6. Essential Elements of Geologic Reports.

    ERIC Educational Resources Information Center

    Webb, Elmer James

    1988-01-01

    Described is a report outline for geologic reports. Essential elements include title; abstract; introduction; stratigraphy; petrography; geochemistry; petrology; geophysics; structural geology; geologic history; modeling; economics; conclusions; and recommendations. (Author/CW)

  7. [Quality evaluation of essential oils].

    PubMed

    Mori, Masahiro; Ikeda, Norikazu; Kato, Yoshiko; Minamino, Miki; Watabe, Kazuhito

    2002-03-01

    Essential oils on the market were analyzed using GC-MS and the main ingredients of each essential oil were quantified. Analysis of the essential oil of Lavandula officinalis (lavender oil) showed that each sample had a different ratio of the contents of main ingredients, such as linalool, linalyl acetate, and camphor. In addition, some commercial lavender oils were analyzed by GC-MS for comparison with the Lavandula flagrans (lavandin oil) and the reference standard. As a result of this analysis, although the components of almost all commercial lavender oils were approximately the same as those of the reference standard, there were a few products that contained more than 0.5% of the amount of camphor in lavandin oil. This suggests that some lavender oil samples are mixed with lavandin oil to lower the price. Commercial essential oils of Melaleuca alternifolia (teatree oil) and Mentha piperita (peppermint oil) were also analyzed by GC-MS. Each of the peppermint oil samples had a different ratio in the content of its main ingredient. With respect to teatree oils, the amount of terpinens in each sample differed. These results led to concern about the efficacy of essential oils. For achieve the expected efficacy of essential oils, correct information on their ingredients should be available and quality control using instrumental analysis should be introduced. PMID:11905050

  8. Essentials of anterior cruciate ligament rupture management.

    PubMed

    Klinge, Stephen A; Sawyer, Gregory A; Hulstyn, Michael J

    2013-05-01

    Anterior cruciate ligament (ACL) rupture is a common knee injury and an understanding of current medical knowledge regarding its management is essential. Accurate and prompt diagnosis requires an awareness of injury mechanisms and risk factors, common symptoms and physical/radiologic findings. Early mobilization and physical therapy improves outcomes regardless of treatment modality. Many older patients regain sufficient stability and function after non-operative rehabilitation. Early ACL reconstruction is appropriate for younger patients and those who engage in activities requiring frequent pivoting and rapid direction changes. ACL surgery involves reconstruction of the torn ligament tissue with various replacement graft options, each with advantages and disadvantages. The guidance of a knowledgeable and experienced therapist is required throughout an intensive and prolonged rehabilitation course. Generally excellent outcomes and low complication rates are expected, but treatment does not prevent late osteoarthritis.

  9. Firefighters Integrated Response Equipment System

    NASA Technical Reports Server (NTRS)

    Kaplan, H.; Abeles, F.

    1978-01-01

    The Firefighters Integrated Response Equipment System (Project FIRES) is a joint National Fire Prevention and Control Administration (NFPCA)/National Aeronautics and Space Administration (NASA) program for the development of an 'ultimate' firefighter's protective ensemble. The overall aim of Project FIRES is to improve firefighter protection against hazards, such as heat, flame, smoke, toxic fumes, moisture, impact penetration, and electricity and, at the same time, improve firefighter performance by increasing maneuverability, lowering weight, and improving human engineering design of his protective ensemble.

  10. Equipment life cycle costs minimised.

    PubMed

    Kuligowski, Sharon

    2004-11-01

    With the cost of energy now a major component of building operating costs, NHS Trust managers increasingly focus on estimating total life cycle costs of equipment such as boiler room and heat, steam and incineration plant. "Life cycle costing" is a broad term and encompasses a wide range of techniques that take into account both initial and future costs as well as the savings of an investment over a period of time. PMID:15575554

  11. Equipment life cycle costs minimised.

    PubMed

    Kuligowski, Sharon

    2004-11-01

    With the cost of energy now a major component of building operating costs, NHS Trust managers increasingly focus on estimating total life cycle costs of equipment such as boiler room and heat, steam and incineration plant. "Life cycle costing" is a broad term and encompasses a wide range of techniques that take into account both initial and future costs as well as the savings of an investment over a period of time.

  12. [Equipment and technology in robotics].

    PubMed

    Murphy, Declan; Challacombe, Ben; Nedas, Tim; Elhage, Oussama; Althoefer, Kaspar; Seneviratne, Lakmal; Dasgupta, Prokar

    2007-05-01

    We review the evolution and current status of robotic equipment and technology in urology. We also describe future developments in the key areas of virtual reality simulation, mechatronics and nanorobotics. The history of robotic technology is reviewed and put into the context of current systems. Experts in the associated fields of nanorobotics, mechatronics and virtual reality simulation simulation review the important future developments in these areas.

  13. Used energy-related laboratory equipment grant program for institutions of higher learning. Eligible equipment catalog

    SciTech Connect

    Not Available

    1994-07-01

    This is a listing of energy related equipment available through the Energy-Related Laboratory Equipment Grant Program which grants used equipment to institutions of higher education for energy-related research. Information included is an overview of the program, how to apply for a grant of equipment, eligibility requirements, types of equipment available, and the costs for the institution.

  14. Power Product Equipment Technician: Lawn and Garden Equipment. Teacher Edition. Student Version.

    ERIC Educational Resources Information Center

    Hilley, Robert

    This packet contains teacher and student editions for lawn and garden equipment repair and maintenance, intended for the preparation of power product equipment technicians. This publication contains four units: (1) introduction to lawn and garden equipment; (2) light-duty lawn and garden equipment; (3) heavy-duty lawn and garden equipment; and (4)…

  15. Vibration budget for observatory equipment

    NASA Astrophysics Data System (ADS)

    MacMartin, Douglas G.; Thompson, Hugh

    2015-07-01

    Vibration from equipment mounted on the telescope and in summit support buildings has been a source of performance degradation at existing astronomical observatories, particularly for adaptive optics performance. Rather than relying only on best practices to minimize vibration, we present here a vibration budget that specifies allowable force levels from each source of vibration in the observatory (e.g., pumps, chillers, cryocoolers, etc.). This design tool helps ensure that the total optical performance degradation due to vibration is less than the corresponding error budget allocation and is also useful in design trade-offs, specifying isolation requirements for equipment, and tightening or widening individual equipment vibration specifications as necessary. The vibration budget relies on model-based analysis of the optical consequences that result from forces applied at different locations and frequencies, including both image jitter and primary mirror segment motion. We develop this tool here for the Thirty Meter Telescope but hope that this approach will be broadly useful to other observatories, not only in the design phase, but for verification and operations as well.

  16. Strategy Guideline: HVAC Equipment Sizing

    SciTech Connect

    Burdick, A.

    2012-02-01

    The heating, ventilation, and air conditioning (HVAC) system is arguably the most complex system installed in a house and is a substantial component of the total house energy use. A right-sized HVAC system will provide the desired occupant comfort and will run efficiently. This Strategy Guideline discusses the information needed to initially select the equipment for a properly designed HVAC system. Right-sizing of an HVAC system involves the selection of equipment and the design of the air distribution system to meet the accurate predicted heating and cooling loads of the house. Right-sizing the HVAC system begins with an accurate understanding of the heating and cooling loads on a space; however, a full HVAC design involves more than just the load estimate calculation - the load calculation is the first step of the iterative HVAC design procedure. This guide describes the equipment selection of a split system air conditioner and furnace for an example house in Chicago, IL as well as a heat pump system for an example house in Orlando, Florida. The required heating and cooling load information for the two example houses was developed in the Department of Energy Building America Strategy Guideline: Accurate Heating and Cooling Load Calculations.

  17. Aging assessment of essential HVAC chillers used in nuclear power plants

    SciTech Connect

    Blahnik, D.E.; Camp, T.W.

    1996-09-01

    The Pacific Northwest Laboratory conducted a comprehensive aging assessment of chillers used in the essential safety air-conditioning systems in nuclear power plants (NPPs). The chillers used, and air-conditioning systems served, vary in design from plant to plant. The review of operating experience indicated that chillers experience aging degradation and failures. The primary aging factors of concern for chillers include vibration, excessive temperatures and pressures, thermal cycling, chemical attack, and poor quality cooling water. The evaluation of Licensee Event Reports (LERs) indicated that about 38% of the failures were primarily related to aging, 55% were partially aging related, and 7% of the failures were unassignable. About 25% of the failures were primarily caused by human, design, procedure, and other errors. The large number of errors is probably directly related to the complexity of chillers and their interfacing systems. Nearly all of the LERs were the result of entering plant Technical Specification Limiting Condition for Operation (LCO) that initiated remedial actions like plant shutdown procedures. The trend for chiller-related LERs has stabilized at about 0.13 LERs per plant year since 1988. Carefully following the vendor procedures and monitoring the equipment can help to minimize and/or eliminate most of the premature failures. Recording equipment performance can be useful for trending analysis. Periodic operation for a few hours on a weekly or monthly basis is useful to remove moisture and non-condensable gases that gradually build up inside the chiller. Chiller pressurization kits are available that will help minimize the amount of moisture and air ingress to low-pressure chillers during standby periods. The assessment of service life condition monitoring of chillers indicated there are many simple to sophisticated methods available that can help in chiller surveillance and monitoring.

  18. Protein stability: a crystallographer’s perspective

    PubMed Central

    Deller, Marc C.; Kong, Leopold; Rupp, Bernhard

    2016-01-01

    Protein stability is a topic of major interest for the biotechnology, pharmaceutical and food industries, in addition to being a daily consideration for academic researchers studying proteins. An understanding of protein stability is essential for optimizing the expression, purification, formulation, storage and structural studies of proteins. In this review, discussion will focus on factors affecting protein stability, on a somewhat practical level, particularly from the view of a protein crystallographer. The differences between protein conformational stability and protein compositional stability will be discussed, along with a brief introduction to key methods useful for analyzing protein stability. Finally, tactics for addressing protein-stability issues during protein expression, purification and crystallization will be discussed. PMID:26841758

  19. Rare essentials: drugs for rare diseases as essential medicines.

    PubMed

    Stolk, Pieter; Willemen, Marjolein J C; Leufkens, Hubert G M

    2006-09-01

    Since 1977, the WHO Model List of Essential Medicines (EML), published by WHO, has provided advice for Member States that struggle to decide which pharmaceutical technologies should be provided to patients within their public health systems. Originating from outside WHO, an incentive system has been put in place by various governments for the development of medicines for rare diseases ("orphan drugs"). With progress in pharmaceutical research (e.g. drugs targeted for narrower indications), these medicines will feature more often on future public health agendas. However, when current definitions for selecting essential medicines are applied strictly, orphan drugs cannot be part of the WHO Essential Medicines Programme, creating the risk that WHO may lose touch with this field. In our opinion WHO should explicitly include orphan drugs in its policy sphere by composing a complementary Orphan Medicines Model List as an addition to the EML. This complementary list of "rare essentials" could aid policy-makers and patients in, for example, emerging countries to improve access to these drugs and stimulate relevant policies. Furthermore, inconsistencies in the current EML with regard to medicines for rare diseases can be resolved. In this paper we propose selection criteria for an Orphan Medicines Model List that could form a departure point for future work towards an extensive WHO Orphan Medicines Programme. PMID:17128345

  20. A simplified spatial model for BWR stability

    SciTech Connect

    Berman, Y.; Lederer, Y.; Meron, E.

    2012-07-01

    A spatial reduced order model for the study of BWR stability, based on the phenomenological model of March-Leuba et al., is presented. As one dimensional spatial dependence of the neutron flux, fuel temperature and void fraction is introduced, it is possible to describe both global and regional oscillations of the reactor power. Both linear stability analysis and numerical analysis were applied in order to describe the parameters which govern the model stability. The results were found qualitatively similar to past results. Doppler reactivity feedback was found essential for the explanation of the different regions of the flow-power stability map. (authors)

  1. Cultural transmission of social essentialism

    PubMed Central

    Rhodes, Marjorie; Leslie, Sarah-Jane; Tworek, Christina M.

    2012-01-01

    Social essentialism entails the belief that certain social categories (e.g., gender, race) mark fundamentally distinct kinds of people. Essentialist beliefs have pernicious consequences, supporting social stereotyping and contributing to prejudice. How does social essentialism develop? In the studies reported here, we tested the hypothesis that generic language facilitates the cultural transmission of social essentialism. Two studies found that hearing generic language about a novel social category diverse for race, ethnicity, age, and sex led 4-y-olds and adults to develop essentialist beliefs about that social category. A third study documented that experimentally inducing parents to hold essentialist beliefs about a novel social category led them to produce more generic language when discussing the category with their children. Thus, generic language facilitates the transmission of essentialist beliefs about social categories from parents to children. PMID:22869722

  2. System Design Description PFP Thermal Stabilization

    SciTech Connect

    RISENMAY, H.R.

    2000-04-25

    The purpose of this document is to provide a system design description (SDD) and design basis for the Plutonium Finishing Plant (PFP) Thermal Stabilization project. The chief objective of the SDD is to document the Structures, Systems, and Components (SSCs) that establish and maintain the facility Safety Envelope necessary for normal safe operation of the facility; as identified in the FSAR, the OSRs, and Safety Assessment Documents (SADs). This safety equipment documentation should satisfy guidelines for the SDD given in WHC-SD-CP-TI-18 1, Criteria for Identification and Control of Equipment Necessary for Preservation of the Safety Envelope and Safe Operation of PFP. The basis for operational, alarm response, maintenance, and surveillance procedures are also identified and justified in this document. This document and its appendices address the following elements of the PFP Thermal Stabilization project: Functional and design requirements; Design description; Safety Envelope Analysis; Safety Equipment Class; and Operational, maintenance and surveillance procedures.

  3. The EQUIP for Educators Program

    ERIC Educational Resources Information Center

    DiBiase, Ann-Marie; Potter, Granville Bud; Gibbs, John C.

    2011-01-01

    There is a need for proactive support and early intervention to meet the needs of behaviorally at-risk students. There is limited opportunity to intervene with effective results, given that stability of antisocial behavior increases dramatically over time. Moreover, if antisocial behavior patterns are not addressed early on, these children tend to…

  4. CE Marking - the Essential Requirements

    NASA Astrophysics Data System (ADS)

    Playle, Mervyn

    The European Union (EU) harmonisation project introduced the CE marking of products to enable the free, unhindered movement of goods throughout the European market. The CE mark replaced the EC mark in the mid 1990s and is fundamental to the New Approach Directives. When a product falls within the scope of a New Approach Directive the manufacturer must comply with the 'goal setting' essential requirements of the directive, to follow one of the conformity assessment procedures provided for, and to draw up the technical documentation specified. Although not mandatory, a manufacturer can choose to satisfy the essential requirements through the application of European harmonised standards.

  5. Analgesic Potential of Essential Oils.

    PubMed

    Sarmento-Neto, José Ferreira; do Nascimento, Lázaro Gomes; Felipe, Cícero Francisco Bezerra; de Sousa, Damião Pergentino

    2015-12-23

    Pain is an unpleasant sensation associated with a wide range of injuries and diseases, and affects approximately 20% of adults in the world. The discovery of new and more effective drugs that can relieve pain is an important research goal in both the pharmaceutical industry and academia. This review describes studies involving antinociceptive activity of essential oils from 31 plant species. Botanical aspects of aromatic plants, mechanisms of action in pain models and chemical composition profiles of the essential oils are discussed. The data obtained in these studies demonstrate the analgesic potential of this group of natural products for therapeutic purposes.

  6. Fire suppression and detection equipment

    SciTech Connect

    E.E. Bates

    2006-01-15

    Inspection and testing guidelines go beyond the 'Code of Federal Regulation'. Title 30 of the US Code of Federal Regulations (30 CFR) contains requirements and references to national standards for inspection, testing and maintenance of fire suppression and detection equipment for mine operators. However, federal requirements have not kept pace with national standards and best practices. The article lists National Fire Protection (NFPA) standards that are referenced by the US Mine Safety and Health Administration (MSHA) in 30 CFR. It then discusses other NFPA Standards excluded from 30 CFR and explains the NFPA standard development process. 2 refs., 3 tabs., 5 photos.

  7. Photographic Equipment Test System (PETS)

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The Photographic Equipment Test System is presented. The device is a mobile optical system designed for evaluating performance of various sensors in a laboratory, in a vacuum chamber or on a flight line. The carriage is designed to allow elevation as well as azimuth control of the direction of the light from the collimator. The pneumatic tires provide an effective vibration isolation system. A target/illumination system is mounted on a motor driven linear slide, and focusing and exposure control can be operated remotely from the small electronics control console.

  8. General aviation avionics equipment maintenance

    NASA Technical Reports Server (NTRS)

    Parker, C. D.; Tommerdahl, J. B.

    1978-01-01

    Maintenance of general aviation avionics equipment was investigated with emphasis on single engine and light twin engine general aviation aircraft. Factors considered include the regulatory agencies, avionics manufacturers, avionics repair stations, the statistical character of the general aviation community, and owners and operators. The maintenance, environment, and performance, repair costs, and reliability of avionics were defined. It is concluded that a significant economic stratification is reflected in the maintenance problems encountered, that careful attention to installations and use practices can have a very positive impact on maintenance problems, and that new technologies and a general growth in general aviation will impact maintenance.

  9. First MAGDAS Equipment in Ecuador

    NASA Astrophysics Data System (ADS)

    Lopez, E.; Maeda, G.; Vicente, K.; Yumoto, K.; Vasquez, N.; Matsushita, H.; Shishime, A.; Vasconez, C.

    2014-01-01

    The Magnetic Data Acquisition System (MAGDAS) was installed in the protected Jerusalem Park in Malchingui- Ecuador in October of 2012, under the joint collabo ration between Kyushu University of Japan and the Quito Astronomical Observatory of the National Polytechnic School of Ecuador. In this paper, we describe the installation process and present the preliminary data obtained with the MAGDAS equip ment. The behavior of the four components, D, H, Z and F allow us to see the importance of having the Ecuador station where the magnetic field has not been systematically measured before, in valuable contribution to study the equatorial electrodynamics.

  10. HAND TRUCK FOR HANDLING EQUIPMENT

    DOEpatents

    King, D.W.

    1959-02-24

    A truck is described for the handling of large and relatively heavy pieces of equipment and particularly for the handling of ion source units for use in calutrons. The truck includes a chassis and a frame pivoted to the chassis so as to be operable to swing in the manner of a boom. The frame has spaced members so arranged that the device to be handled can be suspended between or passed between these spaced members and also rotated with respect to the frame when the device is secured to the spaced members.

  11. 40 CFR 264.32 - Required equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... handled at the facility could require a particular kind of equipment specified below: (a) An internal... supply water hose streams, or foam producing equipment, or automatic sprinklers, or water spray systems....

  12. 40 CFR 264.32 - Required equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... handled at the facility could require a particular kind of equipment specified below: (a) An internal... supply water hose streams, or foam producing equipment, or automatic sprinklers, or water spray systems....

  13. 40 CFR 264.32 - Required equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... handled at the facility could require a particular kind of equipment specified below: (a) An internal... supply water hose streams, or foam producing equipment, or automatic sprinklers, or water spray systems....

  14. 40 CFR 264.32 - Required equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... handled at the facility could require a particular kind of equipment specified below: (a) An internal... supply water hose streams, or foam producing equipment, or automatic sprinklers, or water spray systems....

  15. 40 CFR 264.32 - Required equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... handled at the facility could require a particular kind of equipment specified below: (a) An internal... supply water hose streams, or foam producing equipment, or automatic sprinklers, or water spray systems....

  16. Electrical Ground Support Equipment Fabrication, Specification for

    NASA Technical Reports Server (NTRS)

    Denson, Erik C.

    2014-01-01

    This document specifies parts, materials, and processes used in the fabrication, maintenance, repair, and procurement of electrical and electronic control and monitoring equipment associated with ground support equipment (GSE) at the Kennedy Space Center (KSC).

  17. 45 CFR 1183.32 - Equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... INSTITUTE OF MUSEUM AND LIBRARY SERVICES UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND COOPERATIVE...) Management requirements. Procedures for managing equipment (including replacement equipment), whether... system must be developed to ensure adequate safeguards to prevent loss, damage, or theft of the...

  18. 45 CFR 1183.32 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... INSTITUTE OF MUSEUM AND LIBRARY SERVICES UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND COOPERATIVE...) Management requirements. Procedures for managing equipment (including replacement equipment), whether... system must be developed to ensure adequate safeguards to prevent loss, damage, or theft of the...

  19. 45 CFR 1183.32 - Equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... INSTITUTE OF MUSEUM AND LIBRARY SERVICES UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND COOPERATIVE...) Management requirements. Procedures for managing equipment (including replacement equipment), whether... system must be developed to ensure adequate safeguards to prevent loss, damage, or theft of the...

  20. Proceedings of FED remote maintenance equipment workshop

    SciTech Connect

    Sager, P.; Garin, J.; Hager, E.R.; Spampinato, P.T.; Tobias, D.; Young, N.

    1981-11-01

    A workshop was convened in two sessions in January and March 1981, on the remote maintenance equipment for the Fusion Engineering Device (FED). The objectives of the first session were to familiarize the participants with the status of the design of the FED and to develop a remote maintenance equipment list for the FED. The objective of the second session was to have the participants present design concepts for the equipment which had been identified in the first session. The equipment list was developed for general purpose and special purpose equipment. The general purpose equipment was categorized as manipulators and other, while the special purpose equipment was subdivided according to the reactor subsystem it serviced: electrical, magnetic, and nuclear. Both mobile and fixed base manipulators were identified. Handling machines were identified as the major requirement for special purpose equipment.

  1. [Water used for hemodialysis equipment: where is Pseudomonas aeruginosa?].

    PubMed

    Ducki, Sébastien; Francini, Nicolas; Blech, Marie-Françoise

    2005-05-01

    The water used in dilution of the dialysis solutions constitutes an essential element of the efficiency and the safety of this therapeutics. Water must be specifically treated, and some technical rules must be respected, such as disinfection of the equipment for water treatment, to guarantee a satisfying level for whole the installation. This article reports the investigations, which were led to find the spring of Pseudomonas aeruginosa which contamined in a recurring way the water feeding dialysis equipment. The observation of samples'chronology and an analysis of the sanitary pad suggested a contamination during disinfection. Sample of residual water from the pump used for the injection of Dialox identified this reservoir as origin of the contamination. To stop this contamination by P. aeruginosa, a pump maintenance revision and purges of the system were used.

  2. Thermal design and flight validation for laser communicator equipment

    NASA Astrophysics Data System (ADS)

    Meng, Henghui; Geng, Liyin; Tan, Canghai; Li, Guoqiang

    2014-11-01

    Laser communicator equipment, designed for advanced optical communication, with a large capacity communication, good encryption and lightweight structures, etc., has a wide range of applications. As for the special transmission characteristic of optical communication, laser phase in the transmission path should be accurate, and less thermal deformation for the optical parts is required in the working process, so the laser communicator equipment has a high level requirement for temperature. Large power units cooling, outer two-dimensional rotating units, temperature control for rotating cable, and high temperature stability and equality, bring a challenge for thermal design. Using structure -electric-thermo-optical integration technology, active and passive thermal control methods are adopt in thermal design for laser communicator equipment: heat-conducted plate and heat pipe were adopted for heat transfer of high heat-flux parts, a new passive and active thermal control method to solve cable cryogenic problems, and high precision temperature control methods were applied for key parts. In-orbit data were analyzed, and the results prove the thermal design correct, and bring a way to thermal control for the equipment with high heat flux and running parts.

  3. Preventive maintenance prioritization index of medical equipment using quality function deployment.

    PubMed

    Saleh, Neven; Sharawi, Amr A; Elwahed, Manal Abd; Petti, Alberto; Puppato, Daniele; Balestra, Gabriella

    2015-05-01

    Preventive maintenance is a core function of clinical engineering, and it is essential to guarantee the correct functioning of the equipment. The management and control of maintenance activities are equally important to perform maintenance. As the variety of medical equipment increases, accordingly the size of maintenance activities increases, the need for better management and control become essential. This paper aims to develop a new model for preventive maintenance priority of medical equipment using quality function deployment as a new concept in maintenance of medical equipment. We developed a three-domain framework model consisting of requirement, function, and concept. The requirement domain is the house of quality matrix. The second domain is the design matrix. Finally, the concept domain generates a prioritization index for preventive maintenance considering the weights of critical criteria. According to the final scores of those criteria, the prioritization action of medical equipment is carried out. Our model proposes five levels of priority for preventive maintenance. The model was tested on 200 pieces of medical equipment belonging to 17 different departments of two hospitals in Piedmont province, Italy. The dataset includes 70 different types of equipment. The results show a high correlation between risk-based criteria and the prioritization list.

  4. Preventive maintenance prioritization index of medical equipment using quality function deployment.

    PubMed

    Saleh, Neven; Sharawi, Amr A; Elwahed, Manal Abd; Petti, Alberto; Puppato, Daniele; Balestra, Gabriella

    2015-05-01

    Preventive maintenance is a core function of clinical engineering, and it is essential to guarantee the correct functioning of the equipment. The management and control of maintenance activities are equally important to perform maintenance. As the variety of medical equipment increases, accordingly the size of maintenance activities increases, the need for better management and control become essential. This paper aims to develop a new model for preventive maintenance priority of medical equipment using quality function deployment as a new concept in maintenance of medical equipment. We developed a three-domain framework model consisting of requirement, function, and concept. The requirement domain is the house of quality matrix. The second domain is the design matrix. Finally, the concept domain generates a prioritization index for preventive maintenance considering the weights of critical criteria. According to the final scores of those criteria, the prioritization action of medical equipment is carried out. Our model proposes five levels of priority for preventive maintenance. The model was tested on 200 pieces of medical equipment belonging to 17 different departments of two hospitals in Piedmont province, Italy. The dataset includes 70 different types of equipment. The results show a high correlation between risk-based criteria and the prioritization list. PMID:25029522

  5. Large-scale preparation of clove essential oil and eugenol-loaded liposomes using a membrane contactor and a pilot plant.

    PubMed

    Sebaaly, Carine; Greige-Gerges, Hélène; Agusti, Géraldine; Fessi, Hatem; Charcosset, Catherine

    2016-01-01

    Based on our previous study where optimal conditions were defined to encapsulate clove essential oil (CEO) into liposomes at laboratory scale, we scaled-up the preparation of CEO and eugenol (Eug)-loaded liposomes using a membrane contactor (600 mL) and a pilot plant (3 L) based on the principle of ethanol injection method, both equipped with a Shirasu Porous Glass membrane for injection of the organic phase into the aqueous phase. Homogenous, stable, nanometric-sized and multilamellar liposomes with high phospholipid, Eug loading rates and encapsulation efficiency of CEO components were obtained. Saturation of phospholipids and drug concentration in the organic phase may control the liposome stability. Liposomes loaded with other hydrophobic volatile compounds could be prepared at large scale using the ethanol injection method and a membrane for injection.

  6. Large-scale preparation of clove essential oil and eugenol-loaded liposomes using a membrane contactor and a pilot plant.

    PubMed

    Sebaaly, Carine; Greige-Gerges, Hélène; Agusti, Géraldine; Fessi, Hatem; Charcosset, Catherine

    2016-01-01

    Based on our previous study where optimal conditions were defined to encapsulate clove essential oil (CEO) into liposomes at laboratory scale, we scaled-up the preparation of CEO and eugenol (Eug)-loaded liposomes using a membrane contactor (600 mL) and a pilot plant (3 L) based on the principle of ethanol injection method, both equipped with a Shirasu Porous Glass membrane for injection of the organic phase into the aqueous phase. Homogenous, stable, nanometric-sized and multilamellar liposomes with high phospholipid, Eug loading rates and encapsulation efficiency of CEO components were obtained. Saturation of phospholipids and drug concentration in the organic phase may control the liposome stability. Liposomes loaded with other hydrophobic volatile compounds could be prepared at large scale using the ethanol injection method and a membrane for injection. PMID:26099849

  7. Essentials for the Teacher's Toolbox

    ERIC Educational Resources Information Center

    Uhler, Jennifer

    2012-01-01

    Every profession has a set of essential tools for carrying out its work. Airplane mechanics cannot repair engines without sophisticated diagnostics, wrenches, and pliers. Surgeons cannot operate without scalpels and clamps. In contrast, teaching has often been perceived as a profession requiring only students, chalk, and a blackboard in order for…

  8. Five Essentials of Emergency Planning

    ERIC Educational Resources Information Center

    Barnes, Jill M.

    2011-01-01

    Principals and other administrators seem to be perpetually overworked. There is always something that still needs to be done at the end of the day, and it is easy for disaster planning and preparedness to keep slipping to the bottom of the list. However, disaster preparation is essential, even when planning for the unknown. At some point in every…

  9. Essential Components of Peace Education

    ERIC Educational Resources Information Center

    Johnson, David W.; Johnson, Roger T.

    2005-01-01

    Peace education is a key for establishing a consensual peace and maintaining it over time. There are 5 essential elements in building a lasting peace through education. First, a public education system must be established that has compulsory attendance for all children and youth, integrated so students from previously conflicting groups interact…

  10. Essential English for Micronesian Adults.

    ERIC Educational Resources Information Center

    Conrad, Jo Ann; Reinecke, Hank

    This student workbook is designed to help Micronesian adults learn everyday English. Its ten chapters move from simple one-word picture labeling to more abstract ideas in a spiraled fashion, reiterating the essential elements of the English language in different, more complicated ways. Subjects covered include names for everyday objects and…

  11. Essential Ideas for Healthy Childhoods

    ERIC Educational Resources Information Center

    Exchange: The Early Childhood Leaders' Magazine Since 1978, 2012

    2012-01-01

    This article presents essential ideas from various people on how to cultivate healthy childhood. Amelia Gambetti says that in terms of young children, the element of complexity offers to them the possibility to have an opportunity to learn how to think and to generate ideas. Diane Levin shares how a three-year-old kid taught her that children do…

  12. Something Essential about Interdisciplinary Thinking

    ERIC Educational Resources Information Center

    Dreyfuss, Simeon

    2011-01-01

    The integrative thinking essential to interdisciplinary inquiry requires not only critical reflection concerning the points of convergence and dissonance between disciplinary insights, but also something more personal and less predictable that this paper describes as "holding in relationship difference ways of knowing." Using the process…

  13. Essential Medicines in National Constitutions

    PubMed Central

    Toebes, Brigit; Hogerzeil, Hans

    2016-01-01

    Abstract A constitutional guarantee of access to essential medicines has been identified as an important indicator of government commitment to the progressive realization of the right to the highest attainable standard of health. The objective of this study was to evaluate provisions on access to essential medicines in national constitutions, to identify comprehensive examples of constitutional text on medicines that can be used as a model for other countries, and to evaluate the evolution of constitutional medicines-related rights since 2008. Relevant articles were selected from an inventory of constitutional texts from WHO member states. References to states’ legal obligations under international human rights law were evaluated. Twenty-two constitutions worldwide now oblige governments to protect and/or to fulfill accessibility of, availability of, and/or quality of medicines. Since 2008, state responsibilities to fulfill access to essential medicines have expanded in five constitutions, been maintained in four constitutions, and have regressed in one constitution. Government commitments to essential medicines are an important foundation of health system equity and are included increasingly in state constitutions. PMID:27781006

  14. 14 CFR 29.1431 - Electronic equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Electronic equipment. 29.1431 Section 29... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Miscellaneous Equipment § 29.1431 Electronic... operation of any other radio or electronic unit, or system of units, required by this chapter....

  15. 14 CFR 29.1431 - Electronic equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Electronic equipment. 29.1431 Section 29... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Equipment Miscellaneous Equipment § 29.1431 Electronic... operation of any other radio or electronic unit, or system of units, required by this chapter....

  16. 46 CFR 197.346 - Diver's equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... GENERAL PROVISIONS Commercial Diving Operations Equipment § 197.346 Diver's equipment. (a) Each diver using SCUBA must have— (1) Self-contained underwater breathing equipment including— (i) A primary... weight belt capable of quick release; (5) A knife; (6) Swim fins or shoes; (7) A diving wristwatch;...

  17. 46 CFR 197.346 - Diver's equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... GENERAL PROVISIONS Commercial Diving Operations Equipment § 197.346 Diver's equipment. (a) Each diver using SCUBA must have— (1) Self-contained underwater breathing equipment including— (i) A primary... weight belt capable of quick release; (5) A knife; (6) Swim fins or shoes; (7) A diving wristwatch;...

  18. 46 CFR 197.346 - Diver's equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... GENERAL PROVISIONS Commercial Diving Operations Equipment § 197.346 Diver's equipment. (a) Each diver using SCUBA must have— (1) Self-contained underwater breathing equipment including— (i) A primary... weight belt capable of quick release; (5) A knife; (6) Swim fins or shoes; (7) A diving wristwatch;...

  19. 14 CFR 25.1561 - Safety equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Safety equipment. 25.1561 Section 25.1561 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS....1561 Safety equipment. (a) Each safety equipment control to be operated by the crew in emergency,...

  20. 14 CFR 27.1561 - Safety equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Safety equipment. 27.1561 Section 27.1561 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... Safety equipment. (a) Each safety equipment control to be operated by the crew in emergency, such...

  1. 14 CFR 25.1561 - Safety equipment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Safety equipment. 25.1561 Section 25.1561 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS....1561 Safety equipment. (a) Each safety equipment control to be operated by the crew in emergency,...

  2. 14 CFR 25.1561 - Safety equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Safety equipment. 25.1561 Section 25.1561 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS....1561 Safety equipment. (a) Each safety equipment control to be operated by the crew in emergency,...

  3. 14 CFR 27.1561 - Safety equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Safety equipment. 27.1561 Section 27.1561 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... Safety equipment. (a) Each safety equipment control to be operated by the crew in emergency, such...

  4. 14 CFR 29.1561 - Safety equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Safety equipment. 29.1561 Section 29.1561 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS....1561 Safety equipment. (a) Each safety equipment control to be operated by the crew in emergency,...

  5. 14 CFR 29.1561 - Safety equipment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Safety equipment. 29.1561 Section 29.1561 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS....1561 Safety equipment. (a) Each safety equipment control to be operated by the crew in emergency,...

  6. 14 CFR 27.1561 - Safety equipment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Safety equipment. 27.1561 Section 27.1561 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... Safety equipment. (a) Each safety equipment control to be operated by the crew in emergency, such...

  7. 14 CFR 29.1561 - Safety equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Safety equipment. 29.1561 Section 29.1561 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS....1561 Safety equipment. (a) Each safety equipment control to be operated by the crew in emergency,...

  8. 33 CFR 175.135 - Existing equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Existing equipment. 175.135 Section 175.135 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) BOATING SAFETY EQUIPMENT REQUIREMENTS Visual Distress Signals § 175.135 Existing equipment....

  9. 46 CFR 121.210 - Heating equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Heating equipment. 121.210 Section 121.210 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150... SYSTEMS AND EQUIPMENT Cooking and Heating § 121.210 Heating equipment. (a) Each heater must be...

  10. 46 CFR 121.210 - Heating equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Heating equipment. 121.210 Section 121.210 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150... SYSTEMS AND EQUIPMENT Cooking and Heating § 121.210 Heating equipment. (a) Each heater must be...

  11. 46 CFR 121.210 - Heating equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Heating equipment. 121.210 Section 121.210 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150... SYSTEMS AND EQUIPMENT Cooking and Heating § 121.210 Heating equipment. (a) Each heater must be...

  12. 46 CFR 121.210 - Heating equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Heating equipment. 121.210 Section 121.210 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150... SYSTEMS AND EQUIPMENT Cooking and Heating § 121.210 Heating equipment. (a) Each heater must be...

  13. 46 CFR 121.210 - Heating equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Heating equipment. 121.210 Section 121.210 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150... SYSTEMS AND EQUIPMENT Cooking and Heating § 121.210 Heating equipment. (a) Each heater must be...

  14. 44 CFR 13.32 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... LOCAL GOVERNMENTS Post-Award Requirements Changes, Property, and Subawards § 13.32 Equipment. (a) Title... as follows: (1) Items of equipment with a current per-unit fair market value of less than $5,000 may...) Items of equipment with a current per unit fair market value in excess of $5,000 may be retained or...

  15. 46 CFR 131.590 - Firefighting equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Firefighting equipment. 131.590 Section 131.590 Shipping..., Drills, and Inspections § 131.590 Firefighting equipment. (a) The master shall ensure that the vessel's required firefighting equipment is on board in the prescribed location and always ready for use, other...

  16. 46 CFR 131.590 - Firefighting equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Firefighting equipment. 131.590 Section 131.590 Shipping..., Drills, and Inspections § 131.590 Firefighting equipment. (a) The master shall ensure that the vessel's required firefighting equipment is on board in the prescribed location and always ready for use, other...

  17. 46 CFR 169.839 - Firefighting equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Firefighting equipment. 169.839 Section 169.839 Shipping... Operations Tests, Drills, and Inspections § 169.839 Firefighting equipment. (a) The master or person in charge shall ensure that the vessel's firefighting equipment is at all times ready for use and that...

  18. 46 CFR 169.839 - Firefighting equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Firefighting equipment. 169.839 Section 169.839 Shipping... Operations Tests, Drills, and Inspections § 169.839 Firefighting equipment. (a) The master or person in charge shall ensure that the vessel's firefighting equipment is at all times ready for use and that...

  19. 46 CFR 131.590 - Firefighting equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Firefighting equipment. 131.590 Section 131.590 Shipping..., Drills, and Inspections § 131.590 Firefighting equipment. (a) The master shall ensure that the vessel's required firefighting equipment is on board in the prescribed location and always ready for use, other...

  20. 46 CFR 131.590 - Firefighting equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Firefighting equipment. 131.590 Section 131.590 Shipping..., Drills, and Inspections § 131.590 Firefighting equipment. (a) The master shall ensure that the vessel's required firefighting equipment is on board in the prescribed location and always ready for use, other...

  1. 46 CFR 131.590 - Firefighting equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Firefighting equipment. 131.590 Section 131.590 Shipping..., Drills, and Inspections § 131.590 Firefighting equipment. (a) The master shall ensure that the vessel's required firefighting equipment is on board in the prescribed location and always ready for use, other...

  2. 46 CFR 169.839 - Firefighting equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Firefighting equipment. 169.839 Section 169.839 Shipping... Operations Tests, Drills, and Inspections § 169.839 Firefighting equipment. (a) The master or person in charge shall ensure that the vessel's firefighting equipment is at all times ready for use and that...

  3. 46 CFR 169.839 - Firefighting equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Firefighting equipment. 169.839 Section 169.839 Shipping... Operations Tests, Drills, and Inspections § 169.839 Firefighting equipment. (a) The master or person in charge shall ensure that the vessel's firefighting equipment is at all times ready for use and that...

  4. 14 CFR 121.605 - Airplane equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Airplane equipment. 121.605 Section 121.605..., FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.605 Airplane equipment. No person may dispatch or release an airplane unless it is airworthy and is equipped as prescribed in §...

  5. 10 CFR 431.404 - Imported equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Imported equipment. 431.404 Section 431.404 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT General Provisions § 431.404 Imported equipment. (a) Under sections 331 and 345 of the Act,...

  6. 10 CFR 431.405 - Exported equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Exported equipment. 431.405 Section 431.405 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT General Provisions § 431.405 Exported equipment. Under Sections 330 and 345 of the Act, this...

  7. 46 CFR 28.405 - Hydraulic equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Hydraulic equipment. 28.405 Section 28.405 Shipping... Operate With More Than 16 Individuals on Board § 28.405 Hydraulic equipment. (a) Each hydraulic system... than four times the system maximum operating pressure. (c) Each hydraulic system must be equipped...

  8. 46 CFR 28.880 - Hydraulic equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Hydraulic equipment. 28.880 Section 28.880 Shipping... INDUSTRY VESSELS Aleutian Trade Act Vessels § 28.880 Hydraulic equipment. (a) Each hydraulic system must be... times the system's maximum operating pressure. (c) Each hydraulic system must be equipped with at...

  9. 40 CFR 65.103 - Equipment identification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 16 2013-07-01 2013-07-01 false Equipment identification. 65.103 Section 65.103 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONSOLIDATED FEDERAL AIR RULE Equipment Leaks § 65.103 Equipment identification. (a)...

  10. 46 CFR 28.405 - Hydraulic equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... than four times the system maximum operating pressure. (c) Each hydraulic system must be equipped with... 46 Shipping 1 2013-10-01 2013-10-01 false Hydraulic equipment. 28.405 Section 28.405 Shipping... Operate With More Than 16 Individuals on Board § 28.405 Hydraulic equipment. (a) Each hydraulic...

  11. 46 CFR 28.405 - Hydraulic equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... than four times the system maximum operating pressure. (c) Each hydraulic system must be equipped with... 46 Shipping 1 2011-10-01 2011-10-01 false Hydraulic equipment. 28.405 Section 28.405 Shipping... Operate With More Than 16 Individuals on Board § 28.405 Hydraulic equipment. (a) Each hydraulic...

  12. 46 CFR 28.405 - Hydraulic equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... than four times the system maximum operating pressure. (c) Each hydraulic system must be equipped with... 46 Shipping 1 2014-10-01 2014-10-01 false Hydraulic equipment. 28.405 Section 28.405 Shipping... Operate With More Than 16 Individuals on Board § 28.405 Hydraulic equipment. (a) Each hydraulic...

  13. 46 CFR 28.405 - Hydraulic equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... than four times the system maximum operating pressure. (c) Each hydraulic system must be equipped with... 46 Shipping 1 2012-10-01 2012-10-01 false Hydraulic equipment. 28.405 Section 28.405 Shipping... Operate With More Than 16 Individuals on Board § 28.405 Hydraulic equipment. (a) Each hydraulic...

  14. 47 CFR 73.1610 - Equipment tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Equipment tests. 73.1610 Section 73.1610... Rules Applicable to All Broadcast Stations § 73.1610 Equipment tests. (a) During the process of..., without further authority from the FCC, conduct equipment tests for the purpose of making such...

  15. 47 CFR 78.23 - Equipment tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Equipment tests. 78.23 Section 78.23... SERVICE Applications and Licenses § 78.23 Equipment tests. (a) Following the grant of a CARS license, the... Commission, conduct equipment tests for the purpose of such adjustments and measurements as may be...

  16. 47 CFR 74.13 - Equipment tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Equipment tests. 74.13 Section 74.13... Services in Part 74 § 74.13 Equipment tests. (a) During the process of construction of any class of radio... equipment tests for the purpose of such adjustments and measurements as may be necessary to...

  17. 47 CFR 74.13 - Equipment tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Equipment tests. 74.13 Section 74.13... Services in Part 74 § 74.13 Equipment tests. (a) During the process of construction of any class of radio... equipment tests for the purpose of such adjustments and measurements as may be necessary to...

  18. 47 CFR 73.1610 - Equipment tests.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Equipment tests. 73.1610 Section 73.1610... Rules Applicable to All Broadcast Stations § 73.1610 Equipment tests. (a) During the process of..., without further authority from the FCC, conduct equipment tests for the purpose of making such...

  19. 47 CFR 78.23 - Equipment tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Equipment tests. 78.23 Section 78.23... SERVICE Applications and Licenses § 78.23 Equipment tests. (a) Following the grant of a CARS license, the... Commission, conduct equipment tests for the purpose of such adjustments and measurements as may be...

  20. 47 CFR 74.852 - Equipment changes.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Equipment changes. 74.852 Section 74.852... Equipment changes. (a) The licensee of a low power auxiliary station may make any changes in the equipment... prior Commission approval: Provided, The proposed changes will not depart from any of the terms of...

  1. 47 CFR 74.651 - Equipment changes.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Equipment changes. 74.651 Section 74.651... Stations § 74.651 Equipment changes. (a) Modifications may be made to an existing authorization in...) Permissible changes in equipment operating in the bands 18.3-18.58 GHz and 19.26-19.3 GHz....

  2. 47 CFR 74.551 - Equipment changes.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Equipment changes. 74.551 Section 74.551... § 74.551 Equipment changes. (a) Modifications may be made to an existing authorization in accordance with §§ 1.929 and 1.947 of this chapter. (b) Permissible changes in equipment operating in the bands...

  3. 47 CFR 74.852 - Equipment changes.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Equipment changes. 74.852 Section 74.852... Equipment changes. (a) The licensee of a low power auxiliary station may make any changes in the equipment... prior Commission approval: Provided, The proposed changes will not depart from any of the terms of...

  4. 47 CFR 74.651 - Equipment changes.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Equipment changes. 74.651 Section 74.651... Stations § 74.651 Equipment changes. (a) Modifications may be made to an existing authorization in...) Permissible changes in equipment operating in the bands 18.3-18.58 GHz and 19.26-19.3 GHz....

  5. 47 CFR 74.551 - Equipment changes.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Equipment changes. 74.551 Section 74.551... § 74.551 Equipment changes. (a) Modifications may be made to an existing authorization in accordance with §§ 1.929 and 1.947 of this chapter. (b) Permissible changes in equipment operating in the bands...

  6. 46 CFR 121.220 - Cooking equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Cooking equipment. 121.220 Section 121.220 Shipping... SYSTEMS AND EQUIPMENT Cooking and Heating § 121.220 Cooking equipment. (a) Doors on a cooking appliance... cooking appliance must be installed to prevent movement in heavy seas. (c) For a grill or similar type...

  7. 46 CFR 121.220 - Cooking equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false Cooking equipment. 121.220 Section 121.220 Shipping... SYSTEMS AND EQUIPMENT Cooking and Heating § 121.220 Cooking equipment. (a) Doors on a cooking appliance... cooking appliance must be installed to prevent movement in heavy seas. (c) For a grill or similar type...

  8. 46 CFR 121.220 - Cooking equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Cooking equipment. 121.220 Section 121.220 Shipping... SYSTEMS AND EQUIPMENT Cooking and Heating § 121.220 Cooking equipment. (a) Doors on a cooking appliance... cooking appliance must be installed to prevent movement in heavy seas. (c) For a grill or similar type...

  9. 46 CFR 121.220 - Cooking equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Cooking equipment. 121.220 Section 121.220 Shipping... SYSTEMS AND EQUIPMENT Cooking and Heating § 121.220 Cooking equipment. (a) Doors on a cooking appliance... cooking appliance must be installed to prevent movement in heavy seas. (c) For a grill or similar type...

  10. 30 CFR 77.1914 - Electrical equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Electrical equipment. 77.1914 Section 77.1914... Shaft Sinking § 77.1914 Electrical equipment. (a) Electric equipment employed below the collar of a.... (b) The insulation of all electric conductors employed below the collar of any slope or shaft...

  11. 30 CFR 77.1914 - Electrical equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Electrical equipment. 77.1914 Section 77.1914... Shaft Sinking § 77.1914 Electrical equipment. (a) Electric equipment employed below the collar of a.... (b) The insulation of all electric conductors employed below the collar of any slope or shaft...

  12. 30 CFR 77.1914 - Electrical equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Electrical equipment. 77.1914 Section 77.1914... Shaft Sinking § 77.1914 Electrical equipment. (a) Electric equipment employed below the collar of a.... (b) The insulation of all electric conductors employed below the collar of any slope or shaft...

  13. 10 CFR 431.405 - Exported equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Exported equipment. 431.405 Section 431.405 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT General Provisions § 431.405 Exported equipment. Under Sections 330 and 345 of the Act, this...

  14. 10 CFR 431.404 - Imported equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Imported equipment. 431.404 Section 431.404 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT General Provisions § 431.404 Imported equipment. (a) Under sections 331 and 345 of the Act,...

  15. 45 CFR 2541.320 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Equipment. 2541.320 Section 2541.320 Public... Changes, Property and Subawards § 2541.320 Equipment. (a) Title. Subject to the obligations and conditions set forth in this section, title to equipment acquired under a grant or subgrant will vest...

  16. Inexpensive Physical Education Equipment for Children.

    ERIC Educational Resources Information Center

    Werner, Peter H.; Simmons, Richard A.

    This book presents ideas for constructing and utilizing homemade recreational equipment for elementary school children. Each chapter deals with acquisition of materials, construction of equipment, and developmental objectives and activities for using the equipment with children. A chapter called "Save Your Junk" gives instructions on how to make…

  17. New Trends in School Science Equipment.

    ERIC Educational Resources Information Center

    Lowe, Norman K., Ed.

    This four-part volume examines trends, problems, and issues related to school science equipment. Part 1 focuses on laboratory work and practical activities in science and technology education, considering equipment and curriculum development, equipment development related to curricula in Brazil, uses of local resources for practical work,…

  18. 14 CFR 121.605 - Airplane equipment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Airplane equipment. 121.605 Section 121.605..., FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.605 Airplane equipment. No person may dispatch or release an airplane unless it is airworthy and is equipped as prescribed in §...

  19. 14 CFR 121.605 - Airplane equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Airplane equipment. 121.605 Section 121.605..., FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.605 Airplane equipment. No person may dispatch or release an airplane unless it is airworthy and is equipped as prescribed in §...

  20. 14 CFR 121.605 - Airplane equipment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Airplane equipment. 121.605 Section 121.605..., FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.605 Airplane equipment. No person may dispatch or release an airplane unless it is airworthy and is equipped as prescribed in §...

  1. 29 CFR 95.34 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... § 95.34 Equipment. (a) Title to equipment acquired by a recipient with Federal funds shall vest in the... title vests in the recipient or the Federal Government. (v) Acquisition date (or date received, if the... the Federal Government retains an interest in the equipment. (c) The recipient shall use the...

  2. 7 CFR 550.38 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... number; (iii) Source of the equipment, including the award number; (iv) Whether title vests in the... the Federal Government retains an interest in the equipment. (b) The Cooperator shall use the equipment in the project or program for which it was acquired as long as needed, whether or not the...

  3. 41 CFR 105-72.404 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Title to equipment acquired by a recipient with Federal funds shall vest in the recipient, subject to...) Whether title vests in the recipient or the Federal Government. (v) Acquisition date (or date received, if... retains an interest in the equipment. (c) The recipient shall use the equipment in the project or...

  4. 41 CFR 105-72.404 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) Title to equipment acquired by a recipient with Federal funds shall vest in the recipient, subject to...) Whether title vests in the recipient or the Federal Government. (v) Acquisition date (or date received, if... retains an interest in the equipment. (c) The recipient shall use the equipment in the project or...

  5. 34 CFR 74.34 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Equipment. (a) Title to equipment acquired by a recipient with Federal funds shall vest in the recipient... the award number. (iv) Whether title vests in the recipient or the Federal Government. (v) Acquisition... the Federal Government retains an interest in the equipment. (c) The recipient shall use the...

  6. 29 CFR 95.34 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Equipment. (a) Title to equipment acquired by a recipient with Federal funds shall vest in the recipient... title vests in the recipient or the Federal Government. (v) Acquisition date (or date received, if the... the Federal Government retains an interest in the equipment. (c) The recipient shall use the...

  7. 22 CFR 145.34 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... (a) Title to equipment acquired by a recipient with Federal funds shall vest in the recipient... of the equipment, including the award number. (iv) Whether title vests in the recipient or the... the Federal Government retains an interest in the equipment. (c) The recipient shall use the...

  8. 38 CFR 49.34 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... equipment acquired by a recipient with Federal funds shall vest in the recipient, subject to conditions of...) Whether title vests in the recipient or the Federal Government. (v) Acquisition date (or date received, if... retains an interest in the equipment. (c) The recipient shall use the equipment in the project or...

  9. 43 CFR 12.934 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....934 Equipment. (a) Title to equipment acquired by a recipient with Federal funds shall vest in the...) Whether title vests in the recipient or the Federal Government. (v) Acquisition date (or date received, if... the Federal Government retains an interest in the equipment. (c) The recipient shall use the...

  10. 7 CFR 3019.34 - Equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....34 Equipment. (a) Title to equipment acquired by a recipient with Federal funds shall vest in the..., including the award number. (iv) Whether title vests in the recipient or the Federal Government. (v... the Federal Government retains an interest in the equipment. (c) The recipient shall use the...

  11. 22 CFR 226.34 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... otherwise, title to equipment acquired by a recipient with Federal funds shall vest in the recipient... of the equipment, including the award number. (iv) Whether title vests in the recipient, the Federal... the Federal Government retains an interest in the equipment. (c) The recipient shall use the...

  12. 7 CFR 3019.34 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ....34 Equipment. (a) Title to equipment acquired by a recipient with Federal funds shall vest in the..., including the award number. (iv) Whether title vests in the recipient or the Federal Government. (v... the Federal Government retains an interest in the equipment. (c) The recipient shall use the...

  13. 36 CFR 1210.34 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... (a) Title to equipment acquired by a recipient with NHPRC funds shall vest in the recipient, subject... the award number. (iv) Whether title vests in the recipient or the Federal Government. (v) Acquisition... Government retains an interest in the equipment. (c) The recipient shall use the equipment in the project...

  14. Dental extractions using improvised equipment.

    PubMed

    Iserson, Kenneth V

    2013-12-01

    Extracting a tooth is the final treatment for multiple dental problems. Persons who are not dentists, however, have little experience with tooth extractions. When a remote setting makes it impossible to send a patient for optimal dental treatment, the clinician may need to extract teeth, sometimes using improvised equipment. The following cases of two patients with three carious, painful molars describe such a situation. The non-dental clinicians had to improvise not only appropriate dental tools, but also personal protective equipment, a functional suction machine, medications for a dental block, a dental chair, and dental consent forms and follow-up instructions in the patients' language. In these cases, they also communicated with their patients through a translator. To prepare to do tooth extractions in remote settings, clinicians should learn and practice dental blocks and review extraction techniques before they deploy. If they must do an extraction, clinicians should use the closest approximation available to the appropriate dental tools. When done correctly, a dental extraction can take some time and should not be rushed. PMID:24076092

  15. Carbon Absorber Retrofit Equipment (CARE)

    SciTech Connect

    Klein, Eric

    2015-12-23

    During Project DE-FE0007528, CARE (Carbon Absorber Retrofit Equipment), Neumann Systems Group (NSG) designed, installed and tested a 0.5MW NeuStream® carbon dioxide (CO2) capture system using the patented NeuStream® absorber equipment and concentrated (6 molal) piperazine (PZ) as the solvent at Colorado Springs Utilities’ (CSU’s) Martin Drake pulverized coal (PC) power plant. The 36 month project included design, build and test phases. The 0.5MW NeuStream® CO2 capture system was successfully tested on flue gas from both coal and natural gas combustion sources and was shown to meet project objectives. Ninety percent CO2 removal was achieved with greater than 95% CO2product purity. The absorbers tested support a 90% reduction in absorber volume compared to packed towers and with an absorber parasitic power of less than 1% when configured for operation with a 550MW coal plant. The preliminary techno-economic analysis (TEA) performed by the Energy and Environmental Research Center (EERC) predicted an over-the-fence cost of $25.73/tonne of CO2 captured from a sub-critical PC plant.

  16. Brian Dunlap Examines Experimtal Equipment

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Youngstown, Ohio high school student, W. Brian Dunlap (center), discusses with Dr. Robert Head (right), and Henry Floyd, both of the Marshall Space Flight Center (MSFC), his experiment to be performed aboard the Skylab the following year. His experiment, 'Wave Motion Trough A Liquid in Zero Gravity' used a container attached to the end of a leaf spring which was oscillated at specific rates using two thickness differentiated types of liquids. Dunlap was among 25 winners of a contest in which some 3,500 high school students proposed experiments for the following year's Skylab mission. The nationwide scientific competition was sponsored by the National Science Teachers Association and the National Aeronautics and Space Administration (NASA). The winning students, along with their parents and sponsor teachers, visited MSFC where they met with scientists and engineers, participated in design reviews for their experiments, and toured MSFC facilities. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of additional equipment. The equipment for the experiments was manufactured at MSFC.

  17. Liquid-Liquid Extraction Equipment

    SciTech Connect

    Jack D. Law; Terry A. Todd

    2008-12-01

    Solvent extraction processing has demonstrated the ability to achieve high decontamination factors for uranium and plutonium while operating at high throughputs. Historical application of solvent extraction contacting equipment implies that for the HA cycle (primary separation of uranium and plutonium from fission products) the equipment of choice is pulse columns. This is likely due to relatively short residence times (as compared to mixer-settlers) and the ability of the columns to tolerate solids in the feed. Savannah River successfully operated the F-Canyon with centrifugal contactors in the HA cycle (which have shorter residence times than columns). All three contactors have been successfully deployed in uranium and plutonium purification cycles. Over the past 20 years, there has been significant development of centrifugal contactor designs and they have become very common for research and development applications. New reprocessing plants are being planned in Russia and China and the United States has done preliminary design studies on future reprocessing plants. The choice of contactors for all of these facilities is yet to be determined.

  18. 33 CFR 157.22 - Intact stability requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Intact stability requirements... OIL IN BULK Design, Equipment, and Installation § 157.22 Intact stability requirements. All tank ships of 5,000 DWT and above contracted after December 3, 2001 must comply with the intact...

  19. 33 CFR 157.22 - Intact stability requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Intact stability requirements... OIL IN BULK Design, Equipment, and Installation § 157.22 Intact stability requirements. All tank ships of 5,000 DWT and above contracted after December 3, 2001 must comply with the intact...

  20. 33 CFR 157.22 - Intact stability requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Intact stability requirements... OIL IN BULK Design, Equipment, and Installation § 157.22 Intact stability requirements. All tank ships of 5,000 DWT and above contracted after December 3, 2001 must comply with the intact...

  1. 33 CFR 157.22 - Intact stability requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Intact stability requirements... OIL IN BULK Design, Equipment, and Installation § 157.22 Intact stability requirements. All tank ships of 5,000 DWT and above contracted after December 3, 2001 must comply with the intact...

  2. 33 CFR 157.22 - Intact stability requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Intact stability requirements... OIL IN BULK Design, Equipment, and Installation § 157.22 Intact stability requirements. All tank ships of 5,000 DWT and above contracted after December 3, 2001 must comply with the intact...

  3. Essential Medicines in a High Income Country: Essential to Whom?

    PubMed Central

    2015-01-01

    Objective To explore the perspectives of a diverse group of stakeholders engaged in medicines decision making around what constitutes an “essential” medicine, and how the Essential Medicines List (EML) concept functions in a high income country context. Methods In-depth qualitative semi-structured interviews were conducted with 32 Australian stakeholders, recognised as decision makers, leaders or advisors in the area of medicines reimbursement or supply chain management. Participants were recruited from government, pharmaceutical industry, pharmaceutical wholesale/distribution companies, medicines non-profit organisations, academic health disciplines, hospitals, and consumer groups. Perspectives on the definition and application of the EML concept in a high income country context were thematically analysed using grounded theory approach. Findings Stakeholders found it challenging to describe the EML concept in the Australian context because many perceived it was generally used in resource scarce settings. Stakeholders were unable to distinguish whether nationally reimbursed medicines were essential medicines in Australia. Despite frequent generic drug shortages and high prices paid by consumers, many struggled to describe how the EML concept applied to Australia. Instead, broad inclusion of consumer needs, such as rare and high cost medicines, and consumer involvement in the decision making process, has led to expansive lists of nationally subsidised medicines. Therefore, improved communication and coordination is needed around shared interests between stakeholders regarding how medicines are prioritised and guaranteed in the supply chain. Conclusions This study showed that decision-making in Australia around reimbursement of medicines has strayed from the fundamental utilitarian concept of essential medicines. Many stakeholders involved in medicine reimbursement decisions and management of the supply chain did not consider the EML concept in their approach

  4. STABILIZED OSCILLATOR

    DOEpatents

    Jessen, P.L.; Price, H.J.

    1958-03-18

    This patent relates to sine-wave generators and in particular describes a generator with a novel feedback circuit resulting in improved frequency stability. The generator comprises two triodes having a common cathode circuit connected to oscillate at a frequency and amplitude at which the loop galn of the circutt ls unity, and another pair of triodes having a common cathode circuit arranged as a conventional amplifier. A signal is conducted from the osciliator through a frequency selective network to the amplifier and fed back to the osciliator. The unique feature of the feedback circuit is the amplifier operates in the nonlinear portion of its tube characteristics thereby providing a relatively constant feedback voltage to the oscillator irrespective of the amplitude of its input signal.

  5. Stabilizing brokerage

    PubMed Central

    Stovel, Katherine; Golub, Benjamin; Milgrom, Eva M. Meyersson

    2011-01-01

    A variety of social and economic arrangements exist to facilitate the exchange of goods, services, and information over gaps in social structure. Each of these arrangements bears some relationship to the idea of brokerage, but this brokerage is rarely like the pure and formal economic intermediation seen in some modern markets. Indeed, for reasons illuminated by existing sociological and economic models, brokerage is a fragile relationship. In this paper, we review the causes of instability in brokerage and identify three social mechanisms that can stabilize fragile brokerage relationships: social isolation, broker capture, and organizational grafting. Each of these mechanisms rests on the emergence or existence of supporting institutions. We suggest that organizational grafting may be the most stable and effective resolution to the tensions inherent in brokerage, but it is also the most institutionally demanding. PMID:22198763

  6. Stabilizing brokerage.

    PubMed

    Stovel, Katherine; Golub, Benjamin; Milgrom, Eva M Meyersson

    2011-12-27

    A variety of social and economic arrangements exist to facilitate the exchange of goods, services, and information over gaps in social structure. Each of these arrangements bears some relationship to the idea of brokerage, but this brokerage is rarely like the pure and formal economic intermediation seen in some modern markets. Indeed, for reasons illuminated by existing sociological and economic models, brokerage is a fragile relationship. In this paper, we review the causes of instability in brokerage and identify three social mechanisms that can stabilize fragile brokerage relationships: social isolation, broker capture, and organizational grafting. Each of these mechanisms rests on the emergence or existence of supporting institutions. We suggest that organizational grafting may be the most stable and effective resolution to the tensions inherent in brokerage, but it is also the most institutionally demanding.

  7. Decoupling criteria for multi-connected equipment

    SciTech Connect

    Reddy, G.R.; Kushwaha, H.S.; Mahajan, S.C.; Suzuki, Kohei

    1996-12-01

    Nuclear Power Plant structures generally support equipment, piping systems, computing/controlling systems etc. These equipment and structures may interact with each other during an earthquake. This results in variation in the uncoupled response wherein uncoupled response is calculated for equipment and structure separately. The best way of accounting for interaction effects of structure and equipment is by coupling together and analyzing for a given earthquake load. However, it may not be practicable to couple all the equipment to the structure because of three main reasons. These are: firstly, at the initial design stage of power plant structure all the details of equipment may not be available, secondly, coupling all the equipment may lead to numerical problems in computation because of large difference in stiffness and thirdly, the cost of computation may become very high and time consuming because by coupling all the equipment, size (e.g. number of numerical equations) of the problem becomes very large. In this paper the authors endeavor to present a decoupling model for multi-connected structure-equipment. The applicability of the model will be demonstrated with practical problems like reactor building and equipment. Here onwards equipment is referred as Secondary System (S.S) and structure of Primary System (P.S).

  8. Purex: process and equipment performance

    SciTech Connect

    Orth, D.A.

    1986-01-01

    The Purex process is the solvent extraction system that uses tributyl phosphate as the extractant for separating uranium and plutonium from irradiated reactor fuels. Since the first flowsheet was proposed at Oak Ridge National Laboratory in 1950, the process has endured for over 30 years with only minor modifications. The spread of the technology was rapid, and worldwide use or research on Purex-type processes was reported by the time of the 1955 Geneva Conference. The overall performance of the process has been so good that there are no serious contenders for replacing it soon. This paper presents: process description; equipment performance (mixer-settlers, pulse columns, rapid contactors); fission product decontamination; solvent effects (solvent degradation products); and partitioning of uranium and plutonium.

  9. Antenna Calibration and Measurement Equipment

    NASA Technical Reports Server (NTRS)

    Rochblatt, David J.; Cortes, Manuel Vazquez

    2012-01-01

    A document describes the Antenna Calibration & Measurement Equipment (ACME) system that will provide the Deep Space Network (DSN) with instrumentation enabling a trained RF engineer at each complex to perform antenna calibration measurements and to generate antenna calibration data. This data includes continuous-scan auto-bore-based data acquisition with all-sky data gathering in support of 4th order pointing model generation requirements. Other data includes antenna subreflector focus, system noise temperature and tipping curves, antenna efficiency, reports system linearity, and instrument calibration. The ACME system design is based on the on-the-fly (OTF) mapping technique and architecture. ACME has contributed to the improved RF performance of the DSN by approximately a factor of two. It improved the pointing performances of the DSN antennas and productivity of its personnel and calibration engineers.

  10. Subsea production equipment standardization initiative

    SciTech Connect

    George, N.

    1996-12-31

    This paper examines Shell Expro`s work in simplifying and standardizing its subsea production systems on 10,000 psi, 300 F rated equipment through the use of proven technology and configured to meet common interface requirements. A modular ``building block`` approach to design was adopted, whereby trees are easily converted from one style to another (oil, water or gas lift) by the addition or removal of bolt-on, pre-engineered packages. Standardization of associated control systems has also been applied, together with series hook-up of trees for small developments. A common top-of-tree interface enables vendor interchangeability of tooling. The use of ROV compatible designs for choke and control module change out are expected to provide significant operational cost savings. Common interfaces allow cross-sharing of tooling systems between projects and potentially other operators, and are the catalyst for vendors to develop rental tooling pools.

  11. [Design of transdermal ultrasonophoresis equipment].

    PubMed

    Li, Liangcheng; Zhang, Yongshun; Li, Zhonghong

    2009-02-01

    The recent fast development in biotechnology has resulted in a large number of therapeutic biologicals coming in the foreground for clinical application. Transdermal drug delivery (TDD) is designed for patching the drug on the skin, and then the drug molecules permeate through the skin into the subcutaneous capillary vessels. However,very few drugs can be administered transdermally at the therapeutic levels to pass through the barrier of stratum corneum. Several physical and chemical methods are applied to improve the permeability of skin. Research result shows that the low-frequency ultrasonic technique can extraordinarily increase the rate of permeation. As a result, it is becoming one of the potential methods that serve as the substitutes for traditional methods. In this paper is presented a type of equipment based on MSP430. The principle of design, the structure of hardware, and the applied function in this area are described. PMID:19334582

  12. The Nichols Wing Cutting Equipment

    NASA Technical Reports Server (NTRS)

    Ford, James B

    1923-01-01

    Described here is wing cutting equipment for the economical production of metal wings for wind tunnel models. The machine will make any size of constant-section wing or strut up to one-sixth inch chord by 36-inch span and up to a thickness of one and one-quarter inches. It cuts a smooth, true model that is accurate to within two-thousandths of an inch on any ordinate. The holding jaws are so designed as to leave the model free of chip marks, and the only hand finishing necessary after the cutting is a rub with amunite to remove burrs. The actual change on ordinate in this finishing rub is less than .0002 inches.

  13. Astronaut Alan Bean flies the Astronaut Maneuvering Equipment

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Astronaut Alan L. Bean, Skylab 3 commander, flies the M509 Astronaut Maneuvering Equipment in the foreward dome area of the Orbital Workshop (OWS) on the space station cluster in Earth orbit. Bean is strapped in to the back-mounted, hand-controlled Automatically Stabilized Maneuvering Unit (ASMU). He is wearing a pressure suit for this run of the M509 experiment, but other ASMU tests are done in shirt sleeves. The dome area where the experiment is conducted is about 22 feet in diameter and 19 feet from top to bottom.

  14. Mechanical suppression of essential tremor.

    PubMed

    Rocon, Eduardo; Manto, Mario; Pons, Jose; Camut, Stephane; Belda, Juan Manuel

    2007-01-01

    This paper describes a new treatment for essential tremor. A wearable orthosis, which can be adapted to each configuration of each joint of the upper limb, is able to apply effective dynamic force between consecutive segments of the upper limb and change its biomechanical characteristics. The orthosis is controlled by a computer with a dedicated software application that distinguishes between real time tremor and voluntary movement. The wearable orthosis is able to detect position, rate and acceleration of rotation of the joint by means of a chip gyroscope. This technology was evaluated in six patients suffering from essential tremor. The technique is non invasive and represents an alternative to medication and deep brain stimulation.

  15. Frequency stabilization for mobile satellite terminals via LORAN

    NASA Technical Reports Server (NTRS)

    Ernst, Gregory J.; Kee, Steven M.; Marquart, Robert C.

    1990-01-01

    Digital satellite communication systems require careful management of frequency stability. Historically, frequency stability has been accomplished by continuously powered, high cost, high performance reference oscillators. Today's low cost mobile satellite communication equipment must operate under wide ranging environmental conditions, stabilize quickly after application of power, and provide adequate performance margin to overcome RF link impairments unique to the land mobile environment. Methods for frequency stabilization in land mobile applications must meet these objectives without incurring excessive performance degradation. A frequency stabilization scheme utilizing the LORAN (Long Range Navigation) system is presented.

  16. Stability of casein micelles in milk

    NASA Astrophysics Data System (ADS)

    Tuinier, R.; de Kruif, C. G.

    2002-07-01

    Casein micelles in milk are proteinaceous colloidal particles and are essential for the production of flocculated and gelled products such as yogurt, cheese, and ice-cream. The colloidal stability of casein micelles is described here by a calculation of the pair potential, containing the essential contributions of brush repulsion, electrostatic repulsion, and van der Waals attraction. The parameters required are taken from the literature. The results are expressed by the second osmotic virial coefficient and are quite consistent with experimental findings. It appears that the stability is mainly attributable to a steric layer of κ-casein, which can be described as a salted polyelectrolyte brush.

  17. Equipment qualification (EQ): Risk scoping study

    SciTech Connect

    Bustard, L.D.; Clark, J.; Medford, G.T.; Kolaczkowski, A.M.

    1989-01-01

    The objective of the EQ--Risk Scoping Study was to use probabilistic risk assessment (PRA) techniques (1) to assess the impact of electrical equipment environmental qualification or lack thereof on reactor risk and its uncertainties, and (2) to identify any analyses or testing that may be necessary to reduce the risk or its uncertainties stemming from lack of qualification of equipment important to safety. To achieve these objectives, PRA techniques and insights were employed to identify equipment that must function in accident-induced harsh environments and whose failure would be risk significant. Several components from the resultant list were then selected for more detailed analyses. Accident scenarios and environments, which PRAs suggest are risk significant, were determined for each selected equipment operation. For these accident conditions, both equipment qualification research and test experiences were examined to determine whether equipment accident reliability might differ substantially from the reliability values based on normal operation conditions employed in past PRA analyses. Note, accident reliability information is generally unavailable. Where significant differences were considered probable, parametric risk achievement analyses were used to assess the potential risk impact of the equipment failures. In addition, those equipment qualification practices and outstanding research issues that potentially could impact the accident equipment reliability were noted. This information, when combined with perspectives regarding potential equipment risk impact, provided a basis for assessing the potential risk importance of various EQ practices and issues. Additional discussion regarding the study's approach, conclusions, and recommendations is provided. 54 refs., 9 figs., 33 tabs.

  18. Air emission control equipment - the new challenge for equpiment suppliers

    SciTech Connect

    Lobb, F.H.

    1997-12-31

    The combination of Title V, the CAM Rule and the Credible Evidence Rule demand industrial sites view the selection and operation of emission control devices in a whole new light. No longer can users see these devices as detached end of pipe pieces of equipment essentially purchased off lowest bid. These regulatory changes force plants to fully integrate the operation of these devices into their process control systems and instrumentation. And this is specifically EPA`s stated intent. EPA believes that by forcing sites to exercise the same knowledge and attention to air emissions that they do to operate their production processes, emissions will undergo a natural reduction across the country. Process and operational data that historically has been the sole province of sites becomes public. And compliance with state defined requirements must be demonstrated essentially continuously. This paper explores the new approach to compliance and provides insight through specific field examples/installations of emission control equipment. The author seeks to promote understanding through discussion of these significant regulatory changes.

  19. New Perspectives on the Essential Trace Elements.

    ERIC Educational Resources Information Center

    Frieden, Earl

    1985-01-01

    Provides a comprehensive overview of the 19 essential trace elements, examining: the concept of essentiality; evolution of these elements; possible future essential elements; the lanthanides and actinides; how essential trace elements work; the metalloenzymes; the nonmetals; iodine and the thyroid hormones; and antagonism among these elements. (JN)

  20. Eight essentials of performance measurement.

    PubMed

    Moullin, Max

    2004-01-01

    A well-designed performance measurement system is vital for ensuring that organisations deliver cost-effective, high-quality services that meet the needs of service users. Without feedback on all important aspects and a system for ensuring that the organisation acts on that information, managers are struggling in the dark to improve services. However, performance measurement is not easy, particularly in health and public services where a wide range of stakeholders is involved. This article discusses what the author considers to be the eight essentials of performance measurement. Though described in the context of health and social care, they are important for organisations in all sectors. PMID:15301267

  1. Equipment management user's handbook for property custodians

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The NASA Equipment Management User's Handbook for Property Custodians is issued as an instructional guide for personnel designated as property custodians and technical personnel involved in the acquisition, management, and use of NASA-owned equipment. This handbook provides general information and basic operational procedures for processing equipment transactions through the agency-wide NASA Equipment Management System (NEMS). Each NASA installation must prepare supplementary instructions for local requirements beyond the scope of NASA-wide policies and procedures contained herein, or as specified for local implementation in NHB 4200.1, 'NASA Equipment Management Manual.' NHB 4200.1 sets forth policy, uniform performance standards, and procedural guidance to NASA personnel for the acquisition, management, and use of NASA-owned equipment. This handbook is a controlled document, issued in loose-leaf form and revised by page changes. Additional copies for internal use may be obtained through normal distribution.

  2. WP EMPLACEMENT CONTROL AND COMMUNICATION EQUIPMENT DESCRIPTIONS

    SciTech Connect

    N.T. Raczka

    1997-10-02

    The objective and scope of this document are to list and briefly describe the major control and communication equipment necessary for waste package emplacement at the proposed nuclear waste repository at Yucca Mountain. Primary performance characteristics and some specialized design features of the required equipment are explained and summarized in the individual subsections of this document. This task was evaluated in accordance with QAP-2-0 and found not to be quality affecting. Therefore, this document was prepared in accordance with NAP-MG-012. The following control and communication equipment are addressed in this document: (1) Programmable Logic Controllers (PLC's); (2) Leaky Feeder Radio Frequency Communication Equipment; (3) Slotted Microwave guide Communication Equipment; (4) Vision Systems; (5) Radio Control Equipment; and (6) Enclosure Cooling Systems.

  3. Data acquisition, remote control and equipment monitoring for ISOLDE RILIS

    NASA Astrophysics Data System (ADS)

    Rossel, R. E.; Fedosseev, V. N.; Marsh, B. A.; Richter, D.; Rothe, S.; Wendt, K. D. A.

    2013-12-01

    With a steadily increasing on-line operation time up to a record 3000 h in the year 2012, the Resonance Ionization Laser Ion Source (RILIS) is one of the key components of the ISOLDE on-line isotope user facility at CERN. Ion beam production using the RILIS is essential for many experiments due to the unmatched combination of ionization efficiency and selectivity. To meet the reliability requirements the RILIS is currently operated in shift duty for continuous maintenance of crucial laser parameters such as wavelength, power, beam position and timing, as well as ensuring swift intervention in case of an equipment malfunction. A recent overhaul of the RILIS included the installation of new pump lasers, commercial dye lasers and a complementary, fully solid-state titanium:sapphire laser system. The framework of the upgrade also required the setup of a network-extended, LabVIEW-based system for data acquisition, remote control and equipment monitoring, to support RILIS operators as well as ISOLDE users. The system contributes to four key aspects of RILIS operation: equipment monitoring, machine protection, automated self-reliance, and collaborative data acquisition. The overall concept, technologies used, implementation status and recent applications during the 2012 on-line operation period will be presented along with a summary of future developments.

  4. Physician ownership of medical equipment.

    PubMed

    Reschovsky, James; Cassil, Alwyn; Pham, Hoangmai H

    2010-12-01

    This Data Bulletin presents findings from the Center for Studying Health System Change (HSC) 2008 Health Tracking Physician Survey, a nationally rep­resentative mail survey of U.S. physicians providing at least 20 hours per week of direct patient care. The sample of physicians was drawn from the American Medical Association master file and included active, nonfederal, office- and hospital-based physicians. Residents and fellows were excluded, as well as radiologists, anesthesiologists and pathologists. The survey includes responses from more than 4,700 phy­sicians, and the response rate was 62 percent. Since this Data Bulletin examines the extent of physician practice ownership or leasing of medical equipment, the sample was limited to 2,750 physicians practic­ing in community-based, physician-owned practices, who represent 58 percent of all physicians surveyed. Physicians employed by hospitals, who practiced in hospital-based settings or who worked in hospital-owned practices were excluded.

  5. Construction equipment for lunar base

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Georgia Tech's student design projects for the 1986-1989 academic years relate to the proximate era of lunar exploration and habitation. This era might be described as beginning with robotic prospecting for hydrogen at the lunar poles and ending when a continuously inhabited lunar base is established. The focus was on the design of equipment and systems needed to support the activities contemplated for this portion of the space program. Some specific interests which were identified are listed: Geological exploration; Soils testing; Site preparation; Landing and launch operations; Cargo handling; Base construction; Terrain reconfiguration; Mining, beneficiation and haulage; Pilot - plant manufacturing processes. These design efforts were closely coordinated with those by others as they developed habitat modules, flight vehicles, etc. An example is the development of a standardized inter modal cargo interface. Projects for fall quarter 1986 were: A three-legged walker which serves as a chassis for various interchangeable implements; A digging implement for the walker; A lifting implement for the walker; A cargo interface standard. Some projects were limited to one academic quarter, but most have been pursued for several quarters. A few are expected to evolve over the three-year period.

  6. Wireless "Jump" Starts for Partly Disabled Equipment

    NASA Technical Reports Server (NTRS)

    Castle, K. D.

    1986-01-01

    Equipment activated when normal remote starting does not work Beam from nearby station first carries raw energy and then subsystemactivating signals to equipment crippled by discharged storage batteries. Operators start up equipment without approaching it under hazardous conditions. Potential terrestrial applications for scheme include starting of robots on such remotely-controlled hazardous tasks as handling of explosives or retrieval or deposition of objects in hostile environments.

  7. Decontamination and Decommisioning Equipment Tracking System

    1994-08-26

    DDETS is Relational Data Base Management System (RDBMS) which incorporates 1-D (code 39) and 2-D (PDF417) bar codes into its equipment tracking capabilities. DDETS is compatible with the Reportable Excess Automated Property System (REAPS), and has add, edit, delete and query capabilities for tracking equipment being decontaminated and decommissioned. In addition, bar code technology is utilized in the inventory tracking and shipping of equipment.

  8. "Astro à l'Ecole" equipment plan

    NASA Astrophysics Data System (ADS)

    Chevalier-Théry, S.; Strajnic, J.

    2011-10-01

    "Astro à l'Ecole" is one of the equipment plans organized by the French ministerial plan "Sciences à l'Ecole" in partnership with Paris Observatory. This equipment plan is dedicated to the promotion of Sciences in French school system for upper and lower secondary school pupils based on the discovery of the Astronomy. It started with the transit of Venus in 2004 and is now composed of 31 teams equipped with telescope in all France.

  9. Equipment leasing as a joint venture.

    PubMed

    Figgins, K D

    1986-01-01

    A lack of capital to expand programs, develop new facilities, and replace necessary equipment is a problem frequently confronted in today's medical group practices. Historically, many groups have offset some of the costs of growth by utilizing investment tax credits for depreciable equipment to provide tax shelters for group physicians. Due to recent tax court decisions, however, there is the possibility that many of these tax credits will be disallowed. In an effort to accomplish their original goal of purchasing equipment, passing through tax credits to individual physician partners, and obtaining financial resources at the best market rate, two California medical groups formed an equipment leasing partnership.

  10. Electronic Components Subsystems and Equipment: a Compilation

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Developments in electronic components, subsystems, and equipment are summarized. Topics discussed include integrated circuit components and techniques, circuit components and techniques, and cables and connectors.

  11. 40 CFR 35.6310 - Obtaining equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Personal Property Requirements Under A Cooperative Agreement § 35.6310 Obtaining equipment....

  12. Oil-fueled equipment research: program plan

    SciTech Connect

    Hutchinson, R.A.

    1986-09-01

    The purpose of this document is to define the basis for a US Department of Energy (DOE) program for oil-fueled equipment research. The needs for an benefits of the technical research are explained, and a research plan is presented. This program was developed by Pacific Northwest Laboratory (PNL) with assistance from Steven Winters Associates and input from Brookhaven National Laboratory, Oak Ridge National Laboratory, and many representatives of the heating-oil and oil-fueled equipment industries. The private sector input was extensive, obtained through a series of workshops and formal and informal surveys. The planning effort was directed by the Building Equipment Division of the DOE Office of Buildings and Community Systems. The objective of the oil-fueled equipment research program is to develop the technological basis for new equipment and operating strategies based on improved understanding of oil-burning fundamentals. The program will provide the oil-fueled equipment industry with the basis for developing a new, high-tech generation of equipment, and the oil distributors and equipment installers and consumers with improved knowledge of how best to install and operate such equipment.

  13. Process Equipment Cost Estimation, Final Report

    SciTech Connect

    H.P. Loh; Jennifer Lyons; Charles W. White, III

    2002-01-01

    This report presents generic cost curves for several equipment types generated using ICARUS Process Evaluator. The curves give Purchased Equipment Cost as a function of a capacity variable. This work was performed to assist NETL engineers and scientists in performing rapid, order of magnitude level cost estimates or as an aid in evaluating the reasonableness of cost estimates submitted with proposed systems studies or proposals for new processes. The specific equipment types contained in this report were selected to represent a relatively comprehensive set of conventional chemical process equipment types.

  14. 44 CFR 208.25 - Obsolete equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... HOMELAND SECURITY DISASTER ASSISTANCE NATIONAL URBAN SEARCH AND RESCUE RESPONSE SYSTEM Preparedness... obsolete items on the Equipment Cache List and provide such information to Sponsoring Agencies. (b)...

  15. Reanalyses and Essential Climate Variables

    NASA Technical Reports Server (NTRS)

    Bosilovich, Michael

    2011-01-01

    Reanalyses are a potentially powerful climate data collection driven by observations but also subjected to model bias. Additionally, reanalyses can produce and use essential climate variables in a consistent method. For example, snow cover and soil moisture (among other variables) will eventually be assimilated into the reanalyses, but also provide crucial validation data. Sea surface temperature can be prescribed or assimilated in a coupled reanalysis. The strength of reanalysis lies in the ancillary data that is produced from the modeling components but not routinely observed thereby providing more complete Earth system information. The weakness in this concept is that the model derived data can be affected by model bias and may also change relative to the available observing system. Here, we will review the status of existing reanalyses and the ECVs being considered for the workshop. Purpose of Michael Bosilovich's contribution to the workshop: Michael Bosilovich will represent US reanalysis community in this international discussion of Essential Climate Variables (ECVs) and the relative nature of reanalyses to ECVs.

  16. Epigenetic Modifications in Essential Hypertension

    PubMed Central

    Wise, Ingrid A.; Charchar, Fadi J.

    2016-01-01

    Essential hypertension (EH) is a complex, polygenic condition with no single causative agent. Despite advances in our understanding of the pathophysiology of EH, hypertension remains one of the world’s leading public health problems. Furthermore, there is increasing evidence that epigenetic modifications are as important as genetic predisposition in the development of EH. Indeed, a complex and interactive genetic and environmental system exists to determine an individual’s risk of EH. Epigenetics refers to all heritable changes to the regulation of gene expression as well as chromatin remodelling, without involvement of nucleotide sequence changes. Epigenetic modification is recognized as an essential process in biology, but is now being investigated for its role in the development of specific pathologic conditions, including EH. Epigenetic research will provide insights into the pathogenesis of blood pressure regulation that cannot be explained by classic Mendelian inheritance. This review concentrates on epigenetic modifications to DNA structure, including the influence of non-coding RNAs on hypertension development. PMID:27023534

  17. Economic demand and essential value.

    PubMed

    Hursh, Steven R; Silberberg, Alan

    2008-01-01

    The strength of a rat's eating reflex correlates with hunger level when strength is measured by the response frequency that precedes eating (B. F. Skinner, 1932a, 1932b). On the basis of this finding, Skinner argued response frequency could index reflex strength. Subsequent work documented difficulties with this notion because responding was affected not only by the strengthening properties of the reinforcer but also by the rate-shaping effects of the schedule. This article obviates this problem by measuring strength via methods from behavioral economics. This approach uses demand curves to map how reinforcer consumption changes with changes in the "price" different ratio schedules impose. An exponential equation is used to model these demand curves. The value of this exponential's rate constant is used to scale the strength or essential value of a reinforcer, independent of the scalar dimensions of the reinforcer. Essential value determines the consumption level to be expected at particular prices and the response level that will occur to support that consumption. This approach permits comparing reinforcers that differ in kind, contributing toward the goal of scaling reinforcer value.

  18. Test Room Stability Plan

    SciTech Connect

    Not Available

    1993-01-01

    This plan documents the combination of designs, installations, programs, and activities that ensures that the underground excavations at the Waste Isolation Pilot Plant (WIPP), in which transuranic (TRU) waste may be emplaced during the Test Phase, will remain sufficiently stable and safe during that time. The current ground support systems installed at the WIPP are the result of over ten years of data collection from hundreds of geomechanical instruments and thousands of hours of direct observation of the changing conditions of the openings. In addition, some of the world's most respected experts on salt rock mechanics have provided input in the design process and concurrence on the suitability of the final design. The general mine rockbolt pattern and the ground support system for the test rooms are designed to specifically address the fracture and deformation geometries observed today at the WIPP. After an introductory chapter, this plan describes the general underground design, then proceeds to an account of general ground support performance, and finally focuses on the details of the special test room ground support systems. One such system already installed in Room 1, Panel 1, is described in comprehensive detail. Other test rooms in Panel 1, whether full-size or smaller, will be equipped with systems that ensure stability to the same or equivalent extent. They will benefit from the experience gained in the first test room, which in turn benefitted from the data and knowledge accumulated during previous stages (e.g., the Site and Preliminary Design Validation program) of the project.

  19. Process and equipment development for hot isostatic pressing treatability study

    SciTech Connect

    Bateman, Ken; Wahlquist, Dennis; Malewitz, Tim

    2015-03-01

    Battelle Energy Alliance (BEA), LLC, has developed processes and equipment for a pilot-scale hot isostatic pressing (HIP) treatability study to stabilize and volume reduce radioactive calcine stored at Idaho National Laboratory (INL). In 2009, the U. S. Department of Energy signed a Record of Decision with the state of Idaho selecting HIP technology as the method to treat 5,800 yd^3 (4,400 m^3) of granular zirconia and alumina calcine produced between 1953 and 1992 as a waste byproduct of spent nuclear fuel reprocessing. Since the 1990s, a variety of radioactive and hazardous waste forms have been remotely treated using HIP within INL hot cells. To execute the remote process at INL, waste is loaded into a stainless-steel or aluminum can, which is evacuated, sealed, and placed into a HIP furnace. The HIP simultaneously heats and pressurizes the waste, reducing its volume and increasing its durability. Two 1 gal cans of calcine waste currently stored in a shielded cask were identified as candidate materials for a treatability study involving the HIP process. Equipment and materials for cask-handling and calcine transfer into INL hot cells, as well as remotely operated equipment for waste can opening, particle sizing, material blending, and HIP can loading have been designed and successfully tested. These results demonstrate BEA’s readiness for treatment of INL calcine.

  20. 75 FR 35439 - Medical Diagnostic Equipment Accessibility Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-22

    ... TRANSPORTATION BARRIERS COMPLIANCE BOARD Medical Diagnostic Equipment Accessibility Standards AGENCY... equipment to ensure that such equipment is accessible to, and usable by, individuals with disabilities to... accessibility needs of individuals with disabilities with respect to medical diagnostic equipment and...