Sample records for standard deviation derived

  1. The Standard Deviation of Launch Vehicle Environments

    NASA Technical Reports Server (NTRS)

    Yunis, Isam

    2005-01-01

    Statistical analysis is used in the development of the launch vehicle environments of acoustics, vibrations, and shock. The standard deviation of these environments is critical to accurate statistical extrema. However, often very little data exists to define the standard deviation and it is better to use a typical standard deviation than one derived from a few measurements. This paper uses Space Shuttle and expendable launch vehicle flight data to define a typical standard deviation for acoustics and vibrations. The results suggest that 3dB is a conservative and reasonable standard deviation for the source environment and the payload environment.

  2. Random errors in interferometry with the least-squares method

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang Qi

    2011-01-20

    This investigation analyzes random errors in interferometric surface profilers using the least-squares method when random noises are present. Two types of random noise are considered here: intensity noise and position noise. Two formulas have been derived for estimating the standard deviations of the surface height measurements: one is for estimating the standard deviation when only intensity noise is present, and the other is for estimating the standard deviation when only position noise is present. Measurements on simulated noisy interferometric data have been performed, and standard deviations of the simulated measurements have been compared with those theoretically derived. The relationships havemore » also been discussed between random error and the wavelength of the light source and between random error and the amplitude of the interference fringe.« less

  3. Collinearity in Least-Squares Analysis

    ERIC Educational Resources Information Center

    de Levie, Robert

    2012-01-01

    How useful are the standard deviations per se, and how reliable are results derived from several least-squares coefficients and their associated standard deviations? When the output parameters obtained from a least-squares analysis are mutually independent, as is often assumed, they are reliable estimators of imprecision and so are the functions…

  4. Analytical quality goals derived from the total deviation from patients' homeostatic set points, with a margin for analytical errors.

    PubMed

    Bolann, B J; Asberg, A

    2004-01-01

    The deviation of test results from patients' homeostatic set points in steady-state conditions may complicate interpretation of the results and the comparison of results with clinical decision limits. In this study the total deviation from the homeostatic set point is defined as the maximum absolute deviation for 95% of measurements, and we present analytical quality requirements that prevent analytical error from increasing this deviation to more than about 12% above the value caused by biology alone. These quality requirements are: 1) The stable systematic error should be approximately 0, and 2) a systematic error that will be detected by the control program with 90% probability, should not be larger than half the value of the combined analytical and intra-individual standard deviation. As a result, when the most common control rules are used, the analytical standard deviation may be up to 0.15 times the intra-individual standard deviation. Analytical improvements beyond these requirements have little impact on the interpretability of measurement results.

  5. Estimating active layer thickness and volumetric water content from ground penetrating radar measurements in Barrow, Alaska

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jafarov, E. E.; Parsekian, A. D.; Schaefer, K.

    Ground penetrating radar (GPR) has emerged as an effective tool for estimating active layer thickness (ALT) and volumetric water content (VWC) within the active layer. In August 2013, we conducted a series of GPR and probing surveys using a 500 MHz antenna and metallic probe around Barrow, Alaska. Here, we collected about 15 km of GPR data and 1.5 km of probing data. We describe the GPR data processing workflow from raw GPR data to the estimated ALT and VWC. We then include the corresponding uncertainties for each measured and estimated parameter. The estimated average GPR-derived ALT was 41 cm,more » with a standard deviation of 9 cm. The average probed ALT was 40 cm, with a standard deviation of 12 cm. The average GPR-derived VWC was 0.65, with a standard deviation of 0.14.« less

  6. Estimating active layer thickness and volumetric water content from ground penetrating radar measurements in Barrow, Alaska

    DOE PAGES

    Jafarov, E. E.; Parsekian, A. D.; Schaefer, K.; ...

    2018-01-09

    Ground penetrating radar (GPR) has emerged as an effective tool for estimating active layer thickness (ALT) and volumetric water content (VWC) within the active layer. In August 2013, we conducted a series of GPR and probing surveys using a 500 MHz antenna and metallic probe around Barrow, Alaska. Here, we collected about 15 km of GPR data and 1.5 km of probing data. We describe the GPR data processing workflow from raw GPR data to the estimated ALT and VWC. We then include the corresponding uncertainties for each measured and estimated parameter. The estimated average GPR-derived ALT was 41 cm,more » with a standard deviation of 9 cm. The average probed ALT was 40 cm, with a standard deviation of 12 cm. The average GPR-derived VWC was 0.65, with a standard deviation of 0.14.« less

  7. Sample sizes needed for specified margins of relative error in the estimates of the repeatability and reproducibility standard deviations.

    PubMed

    McClure, Foster D; Lee, Jung K

    2005-01-01

    Sample size formulas are developed to estimate the repeatability and reproducibility standard deviations (Sr and S(R)) such that the actual error in (Sr and S(R)) relative to their respective true values, sigmar and sigmaR, are at predefined levels. The statistical consequences associated with AOAC INTERNATIONAL required sample size to validate an analytical method are discussed. In addition, formulas to estimate the uncertainties of (Sr and S(R)) were derived and are provided as supporting documentation. Formula for the Number of Replicates Required for a Specified Margin of Relative Error in the Estimate of the Repeatability Standard Deviation.

  8. An estimator for the standard deviation of a natural frequency. I.

    NASA Technical Reports Server (NTRS)

    Schiff, A. J.; Bogdanoff, J. L.

    1971-01-01

    A brief review of mean-square approximate systems is given. The case in which the masses are deterministic is considered first in the derivation of an estimator for the upper bound of the standard deviation of a natural frequency. Two examples presented include a two-degree-of-freedom system and a case in which the disorder in the springs is perfectly correlated. For purposes of comparison, a Monte Carlo simulation was done on a digital computer.

  9. Comparison of polyurethane with cyanoacrylate in hemostasis of vascular injury in guinea pigs.

    PubMed

    Kubrusly, Luiz Fernando; Formighieri, Marina Simões; Lago, José Vitor Martins; Graça, Yorgos Luiz Santos de Salles; Sobral, Ana Cristina Lira; Lago, Marianna Martins

    2015-01-01

    To evaluate the behavior of castor oil-derived polyurethane as a hemostatic agent and tissue response after abdominal aortic injury and to compare it with 2-octyl-cyanoacrylate. Twenty-four Guinea Pigs were randomly divided into three groups of eight animals (I, II, and III). The infrarenal abdominal aorta was dissected, clamped proximally and distally to the vascular puncture site. In group I (control), hemostasis was achieved with digital pressure; in group II (polyurethane) castor oil-derived polyurethane was applied, and in group III (cyanoacrylate), 2-octyl-cyanoacrylate was used. Group II was subdivided into IIA and IIB according to the time of preparation of the hemostatic agent. Mean blood loss in groups IIA, IIB and III was 0.002 grams (g), 0.008 g, and 0.170 g, with standard deviation of 0.005 g, 0.005 g, and 0.424 g, respectively (P=0.069). The drying time for cyanoacrylate averaged 81.5 seconds (s) (standard deviation: 51.5 seconds) and 126.1 s (standard deviation: 23.0 s) for polyurethane B (P=0.046). However, there was a trend (P=0.069) for cyanoacrylate to dry more slowly than polyurethane A (mean: 40.5 s; SD: 8.6 s). Furthermore, polyurethane A had a shorter drying time than polyurethane B (P=0.003), mean IIA of 40.5 s (standard deviation: 8.6 s). In group III, 100% of the animals had mild/severe fibrosis, while in group II only 12.5% showed this degree of fibrosis (P=0.001). Polyurethane derived from castor oil showed similar hemostatic behavior to octyl-2-cyanoacrylate. There was less perivascular tissue response with polyurethane when compared with cyanoacrylate.

  10. Comparison of polyurethane with cyanoacrylate in hemostasis of vascular injury in guinea pigs

    PubMed Central

    Kubrusly, Luiz Fernando; Formighieri, Marina Simões; Lago, José Vitor Martins; Graça, Yorgos Luiz Santos de Salles; Sobral, Ana Cristina Lira; Lago, Marianna Martins

    2015-01-01

    Objective To evaluate the behavior of castor oil-derived polyurethane as a hemostatic agent and tissue response after abdominal aortic injury and to compare it with 2-octyl-cyanoacrylate. Methods Twenty-four Guinea Pigs were randomly divided into three groups of eight animals (I, II, and III). The infrarenal abdominal aorta was dissected, clamped proximally and distally to the vascular puncture site. In group I (control), hemostasis was achieved with digital pressure; in group II (polyurethane) castor oil-derived polyurethane was applied, and in group III (cyanoacrylate), 2-octyl-cyanoacrylate was used. Group II was subdivided into IIA and IIB according to the time of preparation of the hemostatic agent. Results Mean blood loss in groups IIA, IIB and III was 0.002 grams (g), 0.008 g, and 0.170 g, with standard deviation of 0.005 g, 0.005 g, and 0.424 g, respectively (P=0.069). The drying time for cyanoacrylate averaged 81.5 seconds (s) (standard deviation: 51.5 seconds) and 126.1 s (standard deviation: 23.0 s) for polyurethane B (P=0.046). However, there was a trend (P=0.069) for cyanoacrylate to dry more slowly than polyurethane A (mean: 40.5 s; SD: 8.6 s). Furthermore, polyurethane A had a shorter drying time than polyurethane B (P=0.003), mean IIA of 40.5 s (standard deviation: 8.6 s). In group III, 100% of the animals had mild/severe fibrosis, while in group II only 12.5% showed this degree of fibrosis (P=0.001). Conclusion Polyurethane derived from castor oil showed similar hemostatic behavior to octyl-2-cyanoacrylate. There was less perivascular tissue response with polyurethane when compared with cyanoacrylate. PMID:25859876

  11. Fluorescein thiocarbamyl amino acids as internal standards for migration time correction in capillary sieving electrophoresis

    PubMed Central

    Pugsley, Haley R.; Swearingen, Kristian E.; Dovichi, Norman J.

    2009-01-01

    A number of algorithms have been developed to correct for migration time drift in capillary electrophoresis. Those algorithms require identification of common components in each run. However, not all components may be present or resolved in separations of complex samples, which can confound attempts for alignment. This paper reports the use of fluorescein thiocarbamyl derivatives of amino acids as internal standards for alignment of 3-(2-furoyl)quinoline-2-carboxaldehyde (FQ)-labeled proteins in capillary sieving electrophoresis. The fluorescein thiocarbamyl derivative of aspartic acid migrates before FQ-labeled proteins and the fluorescein thiocarbamyl derivative of arginine migrates after the FQ-labeled proteins. These compounds were used as internal standards to correct for variations in migration time over a two-week period in the separation of a cellular homogenate. The experimental conditions were deliberately manipulated by varying electric field and sample preparation conditions. Three components of the homogenate were used to evaluate the alignment efficiency. Before alignment, the average relative standard deviation in migration time for these components was 13.3%. After alignment, the average relative standard deviation in migration time for these components was reduced to 0.5%. PMID:19249052

  12. Determination of wind from NIMBUS 6 satellite sounding data

    NASA Technical Reports Server (NTRS)

    Carle, W. E.; Scoggins, J. R.

    1981-01-01

    Objective methods of computing upper level and surface wind fields from NIMBUS 6 satellite sounding data are developed. These methods are evaluated by comparing satellite derived and rawinsonde wind fields on gridded constant pressure charts in four geographical regions. Satellite-derived and hourly observed surface wind fields are compared. Results indicate that the best satellite-derived wind on constant pressure charts is a geostrophic wind derived from highly smoothed fields of geopotential height. Satellite-derived winds computed in this manner and rawinsonde winds show similar circulation patterns except in areas of small height gradients. Magnitudes of the standard deviation of the differences between satellite derived and rawinsonde wind speeds range from approximately 3 to 12 m/sec on constant pressure charts and peak at the jet stream level. Fields of satellite-derived surface wind computed with the logarithmic wind law agree well with fields of observed surface wind in most regions. Magnitudes of the standard deviation of the differences in surface wind speed range from approximately 2 to 4 m/sec, and satellite derived surface winds are able to depict flow across a cold front and around a low pressure center.

  13. Improving estimates of streamflow characteristics using LANDSAT-1 (ERTS-1) imagery. [Delmarva Peninsula

    NASA Technical Reports Server (NTRS)

    Hollyday, E. F. (Principal Investigator)

    1975-01-01

    The author has identified the following significant results. Streamflow characteristics in the Delmarva Peninsula derived from the records of daily discharge of 20 gaged basins are representative of the full range in flow conditions and include all of those commonly used for design or planning purposes. They include annual flood peaks with recurrence intervals of 2, 5, 10, 25, and 50 years, mean annual discharge, standard deviation of the mean annual discharge, mean monthly discharges, standard deviation of the mean monthly discharges, low-flow characteristics, flood volume characteristics, and the discharge equalled or exceeded 50 percent of the time. Streamflow and basin characteristics were related by a technique of multiple regression using a digital computer. A control group of equations was computed using basin characteristics derived from maps and climatological records. An experimental group of equations was computed using basin characteristics derived from LANDSAT imagery as well as from maps and climatological records. Based on a reduction in standard error of estimate equal to or greater than 10 percent, the equations for 12 stream flow characteristics were substantially improved by adding to the analyses basin characteristics derived from LANDSAT imagery.

  14. A Note on the Estimator of the Alpha Coefficient for Standardized Variables Under Normality

    ERIC Educational Resources Information Center

    Hayashi, Kentaro; Kamata, Akihito

    2005-01-01

    The asymptotic standard deviation (SD) of the alpha coefficient with standardized variables is derived under normality. The research shows that the SD of the standardized alpha coefficient becomes smaller as the number of examinees and/or items increase. Furthermore, this research shows that the degree of the dependence of the SD on the number of…

  15. How random is a random vector?

    NASA Astrophysics Data System (ADS)

    Eliazar, Iddo

    2015-12-01

    Over 80 years ago Samuel Wilks proposed that the "generalized variance" of a random vector is the determinant of its covariance matrix. To date, the notion and use of the generalized variance is confined only to very specific niches in statistics. In this paper we establish that the "Wilks standard deviation" -the square root of the generalized variance-is indeed the standard deviation of a random vector. We further establish that the "uncorrelation index" -a derivative of the Wilks standard deviation-is a measure of the overall correlation between the components of a random vector. Both the Wilks standard deviation and the uncorrelation index are, respectively, special cases of two general notions that we introduce: "randomness measures" and "independence indices" of random vectors. In turn, these general notions give rise to "randomness diagrams"-tangible planar visualizations that answer the question: How random is a random vector? The notion of "independence indices" yields a novel measure of correlation for Lévy laws. In general, the concepts and results presented in this paper are applicable to any field of science and engineering with random-vectors empirical data.

  16. Range and Energy Straggling in Ion Beam Transport

    NASA Technical Reports Server (NTRS)

    Wilson, John W.; Tai, Hsiang

    2000-01-01

    A first-order approximation to the range and energy straggling of ion beams is given as a normal distribution for which the standard deviation is estimated from the fluctuations in energy loss events. The standard deviation is calculated by assuming scattering from free electrons with a long range cutoff parameter that depends on the mean excitation energy of the medium. The present formalism is derived by extrapolating Payne's formalism to low energy by systematic energy scaling and to greater depths of penetration by a second-order perturbation. Limited comparisons are made with experimental data.

  17. Odds per Adjusted Standard Deviation: Comparing Strengths of Associations for Risk Factors Measured on Different Scales and Across Diseases and Populations

    PubMed Central

    Hopper, John L.

    2015-01-01

    How can the “strengths” of risk factors, in the sense of how well they discriminate cases from controls, be compared when they are measured on different scales such as continuous, binary, and integer? Given that risk estimates take into account other fitted and design-related factors—and that is how risk gradients are interpreted—so should the presentation of risk gradients. Therefore, for each risk factor X0, I propose using appropriate regression techniques to derive from appropriate population data the best fitting relationship between the mean of X0 and all the other covariates fitted in the model or adjusted for by design (X1, X2, … , Xn). The odds per adjusted standard deviation (OPERA) presents the risk association for X0 in terms of the change in risk per s = standard deviation of X0 adjusted for X1, X2, … , Xn, rather than the unadjusted standard deviation of X0 itself. If the increased risk is relative risk (RR)-fold over A adjusted standard deviations, then OPERA = exp[ln(RR)/A] = RRs. This unifying approach is illustrated by considering breast cancer and published risk estimates. OPERA estimates are by definition independent and can be used to compare the predictive strengths of risk factors across diseases and populations. PMID:26520360

  18. Ambulatory blood pressure monitoring-derived short-term blood pressure variability in primary hyperparathyroidism.

    PubMed

    Concistrè, A; Grillo, A; La Torre, G; Carretta, R; Fabris, B; Petramala, L; Marinelli, C; Rebellato, A; Fallo, F; Letizia, C

    2018-04-01

    Primary hyperparathyroidism is associated with a cluster of cardiovascular manifestations, including hypertension, leading to increased cardiovascular risk. The aim of our study was to investigate the ambulatory blood pressure monitoring-derived short-term blood pressure variability in patients with primary hyperparathyroidism, in comparison with patients with essential hypertension and normotensive controls. Twenty-five patients with primary hyperparathyroidism (7 normotensive,18 hypertensive) underwent ambulatory blood pressure monitoring at diagnosis, and fifteen out of them were re-evaluated after parathyroidectomy. Short-term-blood pressure variability was derived from ambulatory blood pressure monitoring and calculated as the following: 1) Standard Deviation of 24-h, day-time and night-time-BP; 2) the average of day-time and night-time-Standard Deviation, weighted for the duration of the day and night periods (24-h "weighted" Standard Deviation of BP); 3) average real variability, i.e., the average of the absolute differences between all consecutive BP measurements. Baseline data of normotensive and essential hypertension patients were matched for age, sex, BMI and 24-h ambulatory blood pressure monitoring values with normotensive and hypertensive-primary hyperparathyroidism patients, respectively. Normotensive-primary hyperparathyroidism patients showed a 24-h weighted Standard Deviation (P < 0.01) and average real variability (P < 0.05) of systolic blood pressure higher than that of 12 normotensive controls. 24-h average real variability of systolic BP, as well as serum calcium and parathyroid hormone levels, were reduced in operated patients (P < 0.001). A positive correlation of serum calcium and parathyroid hormone with 24-h-average real variability of systolic BP was observed in the entire primary hyperparathyroidism patients group (P = 0.04, P  = 0.02; respectively). Systolic blood pressure variability is increased in normotensive patients with primary hyperparathyroidism and is reduced by parathyroidectomy, and may potentially represent an additional cardiovascular risk factor in this disease.

  19. Determination of the optimal level for combining area and yield estimates

    NASA Technical Reports Server (NTRS)

    Bauer, M. E. (Principal Investigator); Hixson, M. M.; Jobusch, C. D.

    1981-01-01

    Several levels of obtaining both area and yield estimates of corn and soybeans in Iowa were considered: county, refined strata, refined/split strata, crop reporting district, and state. Using the CCEA model form and smoothed weather data, regression coefficients at each level were derived to compute yield and its variance. Variances were also computed with stratum level. The variance of the yield estimates was largest at the state and smallest at the county level for both crops. The refined strata had somewhat larger variances than those associated with the refined/split strata and CRD. For production estimates, the difference in standard deviations among levels was not large for corn, but for soybeans the standard deviation at the state level was more than 50% greater than for the other levels. The refined strata had the smallest standard deviations. The county level was not considered in evaluation of production estimates due to lack of county area variances.

  20. Standard Deviation of Spatially-Averaged Surface Cross Section Data from the TRMM Precipitation Radar

    NASA Technical Reports Server (NTRS)

    Meneghini, Robert; Jones, Jeffrey A.

    2010-01-01

    We investigate the spatial variability of the normalized radar cross section of the surface (NRCS or Sigma(sup 0)) derived from measurements of the TRMM Precipitation Radar (PR) for the period from 1998 to 2009. The purpose of the study is to understand the way in which the sample standard deviation of the Sigma(sup 0) data changes as a function of spatial resolution, incidence angle, and surface type (land/ocean). The results have implications regarding the accuracy by which the path integrated attenuation from precipitation can be inferred by the use of surface scattering properties.

  1. SU-E-T-469: A Practical Approach for the Determination of Small Field Output Factors Using Published Monte Carlo Derived Correction Factors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Calderon, E; Siergiej, D

    2014-06-01

    Purpose: Output factor determination for small fields (less than 20 mm) presents significant challenges due to ion chamber volume averaging and diode over-response. Measured output factor values between detectors are known to have large deviations as field sizes are decreased. No set standard to resolve this difference in measurement exists. We observed differences between measured output factors of up to 14% using two different detectors. Published Monte Carlo derived correction factors were used to address this challenge and decrease the output factor deviation between detectors. Methods: Output factors for Elekta's linac-based stereotactic cone system were measured using the EDGE detectormore » (Sun Nuclear) and the A16 ion chamber (Standard Imaging). Measurements conditions were 100 cm SSD (source to surface distance) and 1.5 cm depth. Output factors were first normalized to a 10.4 cm × 10.4 cm field size using a daisy-chaining technique to minimize the dependence of field size on detector response. An equation expressing the relation between published Monte Carlo correction factors as a function of field size for each detector was derived. The measured output factors were then multiplied by the calculated correction factors. EBT3 gafchromic film dosimetry was used to independently validate the corrected output factors. Results: Without correction, the deviation in output factors between the EDGE and A16 detectors ranged from 1.3 to 14.8%, depending on cone size. After applying the calculated correction factors, this deviation fell to 0 to 3.4%. Output factors determined with film agree within 3.5% of the corrected output factors. Conclusion: We present a practical approach to applying published Monte Carlo derived correction factors to measured small field output factors for the EDGE and A16 detectors. Using this method, we were able to decrease the percent deviation between both detectors from 14.8% to 3.4% agreement.« less

  2. Multiscale analysis of the CMB temperature derivatives

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marcos-Caballero, A.; Martínez-González, E.; Vielva, P., E-mail: marcos@ifca.unican.es, E-mail: martinez@ifca.unican.es, E-mail: vielva@ifca.unican.es

    2017-02-01

    We study the Planck CMB temperature at different scales through its derivatives up to second order, which allows one to characterize the local shape and isotropy of the field. The problem of having an incomplete sky in the calculation and statistical characterization of the derivatives is addressed in the paper. The analysis confirms the existence of a low variance in the CMB at large scales, which is also noticeable in the derivatives. Moreover, deviations from the standard model in the gradient, curvature and the eccentricity tensor are studied in terms of extreme values on the data. As it is expected,more » the Cold Spot is detected as one of the most prominent peaks in terms of curvature, but additionally, when the information of the temperature and its Laplacian are combined, another feature with similar probability at the scale of 10{sup o} is also observed. However, the p -value of these two deviations increase above the 6% when they are referred to the variance calculated from the theoretical fiducial model, indicating that these deviations can be associated to the low variance anomaly. Finally, an estimator of the directional anisotropy for spinorial quantities is introduced, which is applied to the spinors derived from the field derivatives. An anisotropic direction whose probability is <1% is detected in the eccentricity tensor.« less

  3. The joint use of the tangential electric field and surface Laplacian in EEG classification.

    PubMed

    Carvalhaes, C G; de Barros, J Acacio; Perreau-Guimaraes, M; Suppes, P

    2014-01-01

    We investigate the joint use of the tangential electric field (EF) and the surface Laplacian (SL) derivation as a method to improve the classification of EEG signals. We considered five classification tasks to test the validity of such approach. In all five tasks, the joint use of the components of the EF and the SL outperformed the scalar potential. The smallest effect occurred in the classification of a mental task, wherein the average classification rate was improved by 0.5 standard deviations. The largest effect was obtained in the classification of visual stimuli and corresponded to an improvement of 2.1 standard deviations.

  4. Standard deviation of scatterometer measurements from space.

    NASA Technical Reports Server (NTRS)

    Fischer, R. E.

    1972-01-01

    The standard deviation of scatterometer measurements has been derived under assumptions applicable to spaceborne scatterometers. Numerical results are presented which show that, with sufficiently long integration times, input signal-to-noise ratios below unity do not cause excessive degradation of measurement accuracy. The effects on measurement accuracy due to varying integration times and changing the ratio of signal bandwidth to IF filter-noise bandwidth are also plotted. The results of the analysis may resolve a controversy by showing that in fact statistically useful scatterometer measurements can be made from space using a 20-W transmitter, such as will be used on the S-193 experiment for Skylab-A.

  5. Relationship between LiDAR-derived forest canopy height and Landsat images

    Treesearch

    Cristina Pascual; Antonio Garcia-Abril; Warren B. Cohen; Susana Martin-Fernandez

    2010-01-01

    The mean and standard deviation (SD) of light detection and ranging (LiDAR)-derived canopy height are related to forest structure. However, LiDAR data typically cover a limited area and have a high economic cost compared with satellite optical imagery. Optical images may be required to extrapolate LiDAR height measurements across a broad landscape. Different spectral...

  6. Investigation of the Statistics of Pure Tone Sound Power Injection from Low Frequency, Finite Sized Sources in a Reverberant Room

    NASA Technical Reports Server (NTRS)

    Smith, Wayne Farrior

    1973-01-01

    The effect of finite source size on the power statistics in a reverberant room for pure tone excitation was investigated. Theoretical results indicate that the standard deviation of low frequency, pure tone finite sources is always less than that predicted by point source theory and considerably less when the source dimension approaches one-half an acoustic wavelength or greater. A supporting experimental study was conducted utilizing an eight inch loudspeaker and a 30 inch loudspeaker at eleven source positions. The resulting standard deviation of sound power output of the smaller speaker is in excellent agreement with both the derived finite source theory and existing point source theory, if the theoretical data is adjusted to account for experimental incomplete spatial averaging. However, the standard deviation of sound power output of the larger speaker is measurably lower than point source theory indicates, but is in good agreement with the finite source theory.

  7. Nutrient intake values (NIVs): a recommended terminology and framework for the derivation of values.

    PubMed

    King, Janet C; Vorster, Hester H; Tome, Daniel G

    2007-03-01

    Although most countries and regions around the world set recommended nutrient intake values for their populations, there is no standardized terminology or framework for establishing these standards. Different terms used for various components of a set of dietary standards are described in this paper and a common set of terminology is proposed. The recommended terminology suggests that the set of values be called nutrient intake values (NIVs) and that the set be composed of three different values. The average nutrient requirement (ANR) reflects the median requirement for a nutrient in a specific population. The individual nutrient level (INLx) is the recommended level of nutrient intake for all healthy people in the population, which is set at a certain level x above the mean requirement. For example, a value set at 2 standard deviations above the mean requirement would cover the needs of 98% of the population and would be INL98. The third component of the NIVs is an upper nutrient level (UNL), which is the highest level of daily nutrient intake that is likely to pose no risk of adverse health effects for almost all individuals in a specified life-stage group. The proposed framework for deriving a set of NIVs is based on a statistical approach for determining the midpoint of a distribution of requirements for a set of nutrients in a population (the ANR), the standard deviation of the requirements, and an individual nutrient level that assures health at some point above the mean, e.g., 2 standard deviations. Ideally, a second set of distributions of risk of excessive intakes is used as the basis for a UNL.

  8. getimages: Background derivation and image flattening method

    NASA Astrophysics Data System (ADS)

    Men'shchikov, Alexander

    2017-05-01

    getimages performs background derivation and image flattening for high-resolution images obtained with space observatories. It is based on median filtering with sliding windows corresponding to a range of spatial scales from the observational beam size up to a maximum structure width X. The latter is a single free parameter of getimages that can be evaluated manually from the observed image. The median filtering algorithm provides a background image for structures of all widths below X. The same median filtering procedure applied to an image of standard deviations derived from a background-subtracted image results in a flattening image. Finally, a flattened image is computed by dividing the background-subtracted by the flattening image. Standard deviations in the flattened image are now uniform outside sources and filaments. Detecting structures in such radically simplified images results in much cleaner extractions that are more complete and reliable. getimages also reduces various observational and map-making artifacts and equalizes noise levels between independent tiles of mosaicked images. The code (a Bash script) uses FORTRAN utilities from getsources (ascl:1507.014), which must be installed.

  9. A Priori Subgrid Analysis of Temporal Mixing Layers with Evaporating Droplets

    NASA Technical Reports Server (NTRS)

    Okongo, Nora; Bellan, Josette

    1999-01-01

    Subgrid analysis of a transitional temporal mixing layer with evaporating droplets has been performed using three sets of results from a Direct Numerical Simulation (DNS) database, with Reynolds numbers (based on initial vorticity thickness) as large as 600 and with droplet mass loadings as large as 0.5. In the DNS, the gas phase is computed using a Eulerian formulation, with Lagrangian droplet tracking. The Large Eddy Simulation (LES) equations corresponding to the DNS are first derived, and key assumptions in deriving them are first confirmed by computing the terms using the DNS database. Since LES of this flow requires the computation of unfiltered gas-phase variables at droplet locations from filtered gas-phase variables at the grid points, it is proposed to model these by assuming the gas-phase variables to be the sum of the filtered variables and a correction based on the filtered standard deviation; this correction is then computed from the Subgrid Scale (SGS) standard deviation. This model predicts the unfiltered variables at droplet locations considerably better than simply interpolating the filtered variables. Three methods are investigated for modeling the SGS standard deviation: the Smagorinsky approach, the Gradient model and the Scale-Similarity formulation. When the proportionality constant inherent in the SGS models is properly calculated, the Gradient and Scale-Similarity methods give results in excellent agreement with the DNS.

  10. Odds per adjusted standard deviation: comparing strengths of associations for risk factors measured on different scales and across diseases and populations.

    PubMed

    Hopper, John L

    2015-11-15

    How can the "strengths" of risk factors, in the sense of how well they discriminate cases from controls, be compared when they are measured on different scales such as continuous, binary, and integer? Given that risk estimates take into account other fitted and design-related factors-and that is how risk gradients are interpreted-so should the presentation of risk gradients. Therefore, for each risk factor X0, I propose using appropriate regression techniques to derive from appropriate population data the best fitting relationship between the mean of X0 and all the other covariates fitted in the model or adjusted for by design (X1, X2, … , Xn). The odds per adjusted standard deviation (OPERA) presents the risk association for X0 in terms of the change in risk per s = standard deviation of X0 adjusted for X1, X2, … , Xn, rather than the unadjusted standard deviation of X0 itself. If the increased risk is relative risk (RR)-fold over A adjusted standard deviations, then OPERA = exp[ln(RR)/A] = RR(s). This unifying approach is illustrated by considering breast cancer and published risk estimates. OPERA estimates are by definition independent and can be used to compare the predictive strengths of risk factors across diseases and populations. © The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  11. Sea surface temperature measurements with AIRS

    NASA Technical Reports Server (NTRS)

    Aumann, H.

    2003-01-01

    The comparison of global sea surface skin temperature derived from cloud-free AIRS super window channel at 2616 cm-1 (sst2616) with the Real-Time Global Sea Surface Temperature for September 2002 shows surprisingly small standard deviation of 0.44K.

  12. Relationships among the slopes of lines derived from various data analysis techniques and the associated correlation coefficient

    NASA Technical Reports Server (NTRS)

    Cohen, S. C.

    1980-01-01

    A technique for fitting a straight line to a collection of data points is given. The relationships between the slopes and correlation coefficients, and between the corresponding standard deviations and correlation coefficient are given.

  13. Beyond six parameters: Extending Λ CDM

    NASA Astrophysics Data System (ADS)

    Di Valentino, Eleonora; Melchiorri, Alessandro; Silk, Joseph

    2015-12-01

    Cosmological constraints are usually derived under the assumption of a six-parameter Λ CDM theoretical framework or simple one-parameter extensions. In this paper we present, for the first time, cosmological constraints in a significantly extended scenario, varying up to 12 cosmological parameters simultaneously, including the sum of neutrino masses, the neutrino effective number, the dark energy equation of state, the gravitational wave background and the running of the spectral index of primordial perturbations. Using the latest Planck 2015 data release (with polarization), we found no significant indication for extensions to the standard Λ CDM scenario, with the notable exception of the angular power spectrum lensing amplitude, Alens , which is larger than the expected value at more than 2 standard deviations, even when combining the Planck data with BAO and supernovae type Ia external data sets. In our extended cosmological framework, we find that a combined Planck+BAO analysis constrains the value of the rms density fluctuation parameter to σ8=0.781-0.063+0.065 at 95 % C.L., helping to relieve the possible tensions with the CFHTlenS cosmic shear survey. We also find a lower value for the reionization optical depth τ =0.058-0.043+0.040 at 95 % C.L. with respect to the one derived under the assumption of Λ CDM . The scalar spectral index nS is now compatible with a Harrison-Zeldovich spectrum to within 2.5 standard deviations. Combining the Planck data set with the Hubble Space Telescope prior on the Hubble constant provides a value for the equation of state w <-1 at more than 2 standard deviations, while the neutrino effective number is fully compatible with the expectations of the standard three neutrino framework.

  14. Single-Station Sigma for the Iranian Strong Motion Stations

    NASA Astrophysics Data System (ADS)

    Zafarani, H.; Soghrat, M. R.

    2017-11-01

    In development of ground motion prediction equations (GMPEs), the residuals are assumed to have a log-normal distribution with a zero mean and a standard deviation, designated as sigma. Sigma has significant effect on evaluation of seismic hazard for designing important infrastructures such as nuclear power plants and dams. Both aleatory and epistemic uncertainties are involved in the sigma parameter. However, ground-motion observations over long time periods are not available at specific sites and the GMPEs have been derived using observed data from multiple sites for a small number of well-recorded earthquakes. Therefore, sigma is dominantly related to the statistics of the spatial variability of ground motion instead of temporal variability at a single point (ergodic assumption). The main purpose of this study is to reduce the variability of the residuals so as to handle it as epistemic uncertainty. In this regard, it is tried to partially apply the non-ergodic assumption by removing repeatable site effects from total variability of six GMPEs driven from the local, Europe-Middle East and worldwide data. For this purpose, we used 1837 acceleration time histories from 374 shallow earthquakes with moment magnitudes ranging from M w 4.0 to 7.3 recorded at 370 stations with at least two recordings per station. According to estimated single-station sigma for the Iranian strong motion stations, the ratio of event-corrected single-station standard deviation ( Φ ss) to within-event standard deviation ( Φ) is about 0.75. In other words, removing the ergodic assumption on site response resulted in 25% reduction of the within-event standard deviation that reduced the total standard deviation by about 15%.

  15. Filling the voids in the SRTM elevation model — A TIN-based delta surface approach

    NASA Astrophysics Data System (ADS)

    Luedeling, Eike; Siebert, Stefan; Buerkert, Andreas

    The Digital Elevation Model (DEM) derived from NASA's Shuttle Radar Topography Mission is the most accurate near-global elevation model that is publicly available. However, it contains many data voids, mostly in mountainous terrain. This problem is particularly severe in the rugged Oman Mountains. This study presents a method to fill these voids using a fill surface derived from Russian military maps. For this we developed a new method, which is based on Triangular Irregular Networks (TINs). For each void, we extracted points around the edge of the void from the SRTM DEM and the fill surface. TINs were calculated from these points and converted to a base surface for each dataset. The fill base surface was subtracted from the fill surface, and the result added to the SRTM base surface. The fill surface could then seamlessly be merged with the SRTM DEM. For validation, we compared the resulting DEM to the original SRTM surface, to the fill DEM and to a surface calculated by the International Center for Tropical Agriculture (CIAT) from the SRTM data. We calculated the differences between measured GPS positions and the respective surfaces for 187,500 points throughout the mountain range (ΔGPS). Comparison of the means and standard deviations of these values showed that for the void areas, the fill surface was most accurate, with a standard deviation of the ΔGPS from the mean ΔGPS of 69 m, and only little accuracy was lost by merging it to the SRTM surface (standard deviation of 76 m). The CIAT model was much less accurate in these areas (standard deviation of 128 m). The results show that our method is capable of transferring the relative vertical accuracy of a fill surface to the void areas in the SRTM model, without introducing uncertainties about the absolute elevation of the fill surface. It is well suited for datasets with varying altitude biases, which is a common problem of older topographic information.

  16. Uncertainty quantification of CO₂ saturation estimated from electrical resistance tomography data at the Cranfield site

    DOE PAGES

    Yang, Xianjin; Chen, Xiao; Carrigan, Charles R.; ...

    2014-06-03

    A parametric bootstrap approach is presented for uncertainty quantification (UQ) of CO₂ saturation derived from electrical resistance tomography (ERT) data collected at the Cranfield, Mississippi (USA) carbon sequestration site. There are many sources of uncertainty in ERT-derived CO₂ saturation, but we focus on how the ERT observation errors propagate to the estimated CO₂ saturation in a nonlinear inversion process. Our UQ approach consists of three steps. We first estimated the observational errors from a large number of reciprocal ERT measurements. The second step was to invert the pre-injection baseline data and the resulting resistivity tomograph was used as the priormore » information for nonlinear inversion of time-lapse data. We assigned a 3% random noise to the baseline model. Finally, we used a parametric bootstrap method to obtain bootstrap CO₂ saturation samples by deterministically solving a nonlinear inverse problem many times with resampled data and resampled baseline models. Then the mean and standard deviation of CO₂ saturation were calculated from the bootstrap samples. We found that the maximum standard deviation of CO₂ saturation was around 6% with a corresponding maximum saturation of 30% for a data set collected 100 days after injection began. There was no apparent spatial correlation between the mean and standard deviation of CO₂ saturation but the standard deviation values increased with time as the saturation increased. The uncertainty in CO₂ saturation also depends on the ERT reciprocal error threshold used to identify and remove noisy data and inversion constraints such as temporal roughness. Five hundred realizations requiring 3.5 h on a single 12-core node were needed for the nonlinear Monte Carlo inversion to arrive at stationary variances while the Markov Chain Monte Carlo (MCMC) stochastic inverse approach may expend days for a global search. This indicates that UQ of 2D or 3D ERT inverse problems can be performed on a laptop or desktop PC.« less

  17. A Spatio-Temporal Approach for Global Validation and Analysis of MODIS Aerosol Products

    NASA Technical Reports Server (NTRS)

    Ichoku, Charles; Chu, D. Allen; Mattoo, Shana; Kaufman, Yoram J.; Remer, Lorraine A.; Tanre, Didier; Slutsker, Ilya; Holben, Brent N.; Lau, William K. M. (Technical Monitor)

    2001-01-01

    With the launch of the MODIS sensor on the Terra spacecraft, new data sets of the global distribution and properties of aerosol are being retrieved, and need to be validated and analyzed. A system has been put in place to generate spatial statistics (mean, standard deviation, direction and rate of spatial variation, and spatial correlation coefficient) of the MODIS aerosol parameters over more than 100 validation sites spread around the globe. Corresponding statistics are also computed from temporal subsets of AERONET-derived aerosol data. The means and standard deviations of identical parameters from MOMS and AERONET are compared. Although, their means compare favorably, their standard deviations reveal some influence of surface effects on the MODIS aerosol retrievals over land, especially at low aerosol loading. The direction and rate of spatial variation from MODIS are used to study the spatial distribution of aerosols at various locations either individually or comparatively. This paper introduces the methodology for generating and analyzing the data sets used by the two MODIS aerosol validation papers in this issue.

  18. Uncertainty Analysis of Decomposing Polyurethane Foam

    NASA Technical Reports Server (NTRS)

    Hobbs, Michael L.; Romero, Vicente J.

    2000-01-01

    Sensitivity/uncertainty analyses are necessary to determine where to allocate resources for improved predictions in support of our nation's nuclear safety mission. Yet, sensitivity/uncertainty analyses are not commonly performed on complex combustion models because the calculations are time consuming, CPU intensive, nontrivial exercises that can lead to deceptive results. To illustrate these ideas, a variety of sensitivity/uncertainty analyses were used to determine the uncertainty associated with thermal decomposition of polyurethane foam exposed to high radiative flux boundary conditions. The polyurethane used in this study is a rigid closed-cell foam used as an encapsulant. Related polyurethane binders such as Estane are used in many energetic materials of interest to the JANNAF community. The complex, finite element foam decomposition model used in this study has 25 input parameters that include chemistry, polymer structure, and thermophysical properties. The response variable was selected as the steady-state decomposition front velocity calculated as the derivative of the decomposition front location versus time. An analytical mean value sensitivity/uncertainty (MV) analysis was used to determine the standard deviation by taking numerical derivatives of the response variable with respect to each of the 25 input parameters. Since the response variable is also a derivative, the standard deviation was essentially determined from a second derivative that was extremely sensitive to numerical noise. To minimize the numerical noise, 50-micrometer element dimensions and approximately 1-msec time steps were required to obtain stable uncertainty results. As an alternative method to determine the uncertainty and sensitivity in the decomposition front velocity, surrogate response surfaces were generated for use with a constrained Latin Hypercube Sampling (LHS) technique. Two surrogate response surfaces were investigated: 1) a linear surrogate response surface (LIN) and 2) a quadratic response surface (QUAD). The LHS techniques do not require derivatives of the response variable and are subsequently relatively insensitive to numerical noise. To compare the LIN and QUAD methods to the MV method, a direct LHS analysis (DLHS) was performed using the full grid and timestep resolved finite element model. The surrogate response models (LIN and QUAD) are shown to give acceptable values of the mean and standard deviation when compared to the fully converged DLHS model.

  19. A method to estimate statistical errors of properties derived from charge-density modelling

    PubMed Central

    Lecomte, Claude

    2018-01-01

    Estimating uncertainties of property values derived from a charge-density model is not straightforward. A methodology, based on calculation of sample standard deviations (SSD) of properties using randomly deviating charge-density models, is proposed with the MoPro software. The parameter shifts applied in the deviating models are generated in order to respect the variance–covariance matrix issued from the least-squares refinement. This ‘SSD methodology’ procedure can be applied to estimate uncertainties of any property related to a charge-density model obtained by least-squares fitting. This includes topological properties such as critical point coordinates, electron density, Laplacian and ellipticity at critical points and charges integrated over atomic basins. Errors on electrostatic potentials and interaction energies are also available now through this procedure. The method is exemplified with the charge density of compound (E)-5-phenylpent-1-enylboronic acid, refined at 0.45 Å resolution. The procedure is implemented in the freely available MoPro program dedicated to charge-density refinement and modelling. PMID:29724964

  20. The Data from Aeromechanics Test and Analytics -- Management and Analysis Package (DATAMAP). Volume I. User’s Manual.

    DTIC Science & Technology

    1980-12-01

    to sound pressure level in decibels assuming a fre- quency of 1000 Hz. 249 The perceived noisiness values are derived from a formula specified in...Analyses .......... 244 6.i.16 Perceived Noise Level Analysis .............249 6.1.17 Acoustic Weighting Networks ................250 6.2 DERIVATIONS...BAND ANALYSIS BASIC STATISTICAL ANALYSES: *OCTAVE ANALYSIS MEAN *THIRD OCTAVE ANALYSIS VARIANCE *PERCEIVED NOISE LEVEL STANDARD DEVIATION CALCULATION

  1. Using Derivative Estimates to Describe Intraindividual Variability at Multiple Time Scales

    ERIC Educational Resources Information Center

    Deboeck, Pascal R.; Montpetit, Mignon A.; Bergeman, C. S.; Boker, Steven M.

    2009-01-01

    The study of intraindividual variability is central to the study of individuals in psychology. Previous research has related the variance observed in repeated measurements (time series) of individuals to traitlike measures that are logically related. Intraindividual measures, such as intraindividual standard deviation or the coefficient of…

  2. Probabilities of Occurrence of Baro-Fuze System Errors More Than 1000 Feet Too Low Due to Ignoring the Meteorological Forecast

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Charles, B.N.

    1955-05-12

    Charts of the geographical distribution of the annual and seasonal D-values and their standard deviations at altitudes of 4500, 6000, and 7000 feeet over Eurasia are derived, which are used to estimate the frequency of baro system errors.

  3. The Development and Evaluation of Color Systems for Airborne Applications: Fundamental Visual, Perceptual, and Display Systems Considerations.

    DTIC Science & Technology

    1986-02-01

    Ellipses Derived from Both MacAdam’s Empirically Derived Color Matching Standard Deviation and Stiles’ Line Element Predictions 28 2.1.1.2-9 CIELUV Color...Coordinates 141 2.2.2-3 Derivation of CIE (L*, U*, V*) Coordinates 145 2.2.2-4 Three-Dimensional Representation of CIELUV Colcr Difference Estimates...145 2.2.2-5 Application of CIELUV for Estimating Color Difference on an Electronic Color Display 146 2.2.2-6 Color Performance Envelopes and Optimized

  4. The accuracy of ultrashort echo time MRI sequences for medical additive manufacturing.

    PubMed

    van Eijnatten, Maureen; Rijkhorst, Erik-Jan; Hofman, Mark; Forouzanfar, Tymour; Wolff, Jan

    2016-01-01

    Additively manufactured bone models, implants and drill guides are becoming increasingly popular amongst maxillofacial surgeons and dentists. To date, such constructs are commonly manufactured using CT technology that induces ionizing radiation. Recently, ultrashort echo time (UTE) MRI sequences have been developed that allow radiation-free imaging of facial bones. The aim of the present study was to assess the feasibility of UTE MRI sequences for medical additive manufacturing (AM). Three morphologically different dry human mandibles were scanned using a CT and MRI scanner. Additionally, optical scans of all three mandibles were made to acquire a "gold standard". All CT and MRI scans were converted into Standard Tessellation Language (STL) models and geometrically compared with the gold standard. To quantify the accuracy of the AM process, the CT, MRI and gold-standard STL models of one of the mandibles were additively manufactured, optically scanned and compared with the original gold-standard STL model. Geometric differences between all three CT-derived STL models and the gold standard were <1.0 mm. All three MRI-derived STL models generally presented deviations <1.5 mm in the symphyseal and mandibular area. The AM process introduced minor deviations of <0.5 mm. This study demonstrates that MRI using UTE sequences is a feasible alternative to CT in generating STL models of the mandible and would therefore be suitable for surgical planning and AM. Further in vivo studies are necessary to assess the usability of UTE MRI sequences in clinical settings.

  5. Derivation of an analytic expression for the error associated with the noise reduction rating

    NASA Astrophysics Data System (ADS)

    Murphy, William J.

    2005-04-01

    Hearing protection devices are assessed using the Real Ear Attenuation at Threshold (REAT) measurement procedure for the purpose of estimating the amount of noise reduction provided when worn by a subject. The rating number provided on the protector label is a function of the mean and standard deviation of the REAT results achieved by the test subjects. If a group of subjects have a large variance, then it follows that the certainty of the rating should be correspondingly lower. No estimate of the error of a protector's rating is given by existing standards or regulations. Propagation of errors was applied to the Noise Reduction Rating to develop an analytic expression for the hearing protector rating error term. Comparison of the analytic expression for the error to the standard deviation estimated from Monte Carlo simulation of subject attenuations yielded a linear relationship across several protector types and assumptions for the variance of the attenuations.

  6. Spectral combination of spherical gravitational curvature boundary-value problems

    NASA Astrophysics Data System (ADS)

    PitoÅák, Martin; Eshagh, Mehdi; Šprlák, Michal; Tenzer, Robert; Novák, Pavel

    2018-04-01

    Four solutions of the spherical gravitational curvature boundary-value problems can be exploited for the determination of the Earth's gravitational potential. In this article we discuss the combination of simulated satellite gravitational curvatures, i.e., components of the third-order gravitational tensor, by merging these solutions using the spectral combination method. For this purpose, integral estimators of biased- and unbiased-types are derived. In numerical studies, we investigate the performance of the developed mathematical models for the gravitational field modelling in the area of Central Europe based on simulated satellite measurements. Firstly, we verify the correctness of the integral estimators for the spectral downward continuation by a closed-loop test. Estimated errors of the combined solution are about eight orders smaller than those from the individual solutions. Secondly, we perform a numerical experiment by considering the Gaussian noise with the standard deviation of 6.5× 10-17 m-1s-2 in the input data at the satellite altitude of 250 km above the mean Earth sphere. This value of standard deviation is equivalent to a signal-to-noise ratio of 10. Superior results with respect to the global geopotential model TIM-r5 are obtained by the spectral downward continuation of the vertical-vertical-vertical component with the standard deviation of 2.104 m2s-2, but the root mean square error is the largest and reaches 9.734 m2s-2. Using the spectral combination of all gravitational curvatures the root mean square error is more than 400 times smaller but the standard deviation reaches 17.234 m2s-2. The combination of more components decreases the root mean square error of the corresponding solutions while the standard deviations of the combined solutions do not improve as compared to the solution from the vertical-vertical-vertical component. The presented method represents a weight mean in the spectral domain that minimizes the root mean square error of the combined solutions and improves standard deviation of the solution based only on the least accurate components.

  7. Remote auditing of radiotherapy facilities using optically stimulated luminescence dosimeters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lye, Jessica, E-mail: jessica.lye@arpansa.gov.au; Dunn, Leon; Kenny, John

    Purpose: On 1 July 2012, the Australian Clinical Dosimetry Service (ACDS) released its Optically Stimulated Luminescent Dosimeter (OSLD) Level I audit, replacing the previous TLD based audit. The aim of this work is to present the results from this new service and the complete uncertainty analysis on which the audit tolerances are based. Methods: The audit release was preceded by a rigorous evaluation of the InLight® nanoDot OSLD system from Landauer (Landauer, Inc., Glenwood, IL). Energy dependence, signal fading from multiple irradiations, batch variation, reader variation, and dose response factors were identified and quantified for each individual OSLD. The detectorsmore » are mailed to the facility in small PMMA blocks, based on the design of the existing Radiological Physics Centre audit. Modeling and measurement were used to determine a factor that could convert the dose measured in the PMMA block, to dose in water for the facility's reference conditions. This factor is dependent on the beam spectrum. The TPR{sub 20,10} was used as the beam quality index to determine the specific block factor for a beam being audited. The audit tolerance was defined using a rigorous uncertainty calculation. The audit outcome is then determined using a scientifically based two tiered action level approach. Audit outcomes within two standard deviations were defined as Pass (Optimal Level), within three standard deviations as Pass (Action Level), and outside of three standard deviations the outcome is Fail (Out of Tolerance). Results: To-date the ACDS has audited 108 photon beams with TLD and 162 photon beams with OSLD. The TLD audit results had an average deviation from ACDS of 0.0% and a standard deviation of 1.8%. The OSLD audit results had an average deviation of −0.2% and a standard deviation of 1.4%. The relative combined standard uncertainty was calculated to be 1.3% (1σ). Pass (Optimal Level) was reduced to ≤2.6% (2σ), and Fail (Out of Tolerance) was reduced to >3.9% (3σ) for the new OSLD audit. Previously with the TLD audit the Pass (Optimal Level) and Fail (Out of Tolerance) were set at ≤4.0% (2σ) and >6.0% (3σ). Conclusions: The calculated standard uncertainty of 1.3% at one standard deviation is consistent with the measured standard deviation of 1.4% from the audits and confirming the suitability of the uncertainty budget derived audit tolerances. The OSLD audit shows greater accuracy than the previous TLD audit, justifying the reduction in audit tolerances. In the TLD audit, all outcomes were Pass (Optimal Level) suggesting that the tolerances were too conservative. In the OSLD audit 94% of the audits have resulted in Pass (Optimal level) and 6% of the audits have resulted in Pass (Action Level). All Pass (Action level) results have been resolved with a repeat OSLD audit, or an on-site ion chamber measurement.« less

  8. Validation of lignocellulosic biomass carbohydrates determination via acid hydrolysis.

    PubMed

    Zhou, Shengfei; Runge, Troy M

    2014-11-04

    This work studied the two-step acid hydrolysis for determining carbohydrates in lignocellulosic biomass. Estimation of sugar loss based on acid hydrolyzed sugar standards or analysis of sugar derivatives was investigated. Four model substrates (starch, holocellulose, filter paper and cotton) and three levels of acid/material ratios (7.8, 10.3 and 15.4, v/w) were studied to demonstrate the range of test artifacts. The method for carbohydrates estimation based on acid hydrolyzed sugar standards having the most satisfactory carbohydrate recovery and relative standard deviation. Raw material and the acid/material ratio both had significant effect on carbohydrate hydrolysis, suggesting the acid to have impacts beyond a catalyst in the hydrolysis. Following optimal procedures, we were able to reach a carbohydrate recovery of 96% with a relative standard deviation less than 3%. The carbohydrates recovery lower than 100% was likely due to the incomplete hydrolysis of substrates, which was supported by scanning electron microscope (SEM) images. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. Pricing and hedging derivative securities with neural networks: Bayesian regularization, early stopping, and bagging.

    PubMed

    Gençay, R; Qi, M

    2001-01-01

    We study the effectiveness of cross validation, Bayesian regularization, early stopping, and bagging to mitigate overfitting and improving generalization for pricing and hedging derivative securities with daily S&P 500 index daily call options from January 1988 to December 1993. Our results indicate that Bayesian regularization can generate significantly smaller pricing and delta-hedging errors than the baseline neural-network (NN) model and the Black-Scholes model for some years. While early stopping does not affect the pricing errors, it significantly reduces the hedging error (HE) in four of the six years we investigated. Although computationally most demanding, bagging seems to provide the most accurate pricing and delta hedging. Furthermore, the standard deviation of the MSPE of bagging is far less than that of the baseline model in all six years, and the standard deviation of the average HE of bagging is far less than that of the baseline model in five out of six years. We conclude that they be used at least in cases when no appropriate hints are available.

  10. Resistance Training Increases the Variability of Strength Test Scores

    DTIC Science & Technology

    2009-06-08

    standard deviations for pretest and posttest strength measurements. This information was recorded for every strength test used in a total of 377 samples...significant if the posttest standard deviation consistently was larger than the pretest standard deviation. This condition could be satisfied even if...the difference in the standard deviations was small. For example, the posttest standard deviation might be 1% larger than the pretest standard

  11. Using the Standard Deviation of a Region of Interest in an Image to Estimate Camera to Emitter Distance

    PubMed Central

    Cano-García, Angel E.; Lazaro, José Luis; Infante, Arturo; Fernández, Pedro; Pompa-Chacón, Yamilet; Espinoza, Felipe

    2012-01-01

    In this study, a camera to infrared diode (IRED) distance estimation problem was analyzed. The main objective was to define an alternative to measures depth only using the information extracted from pixel grey levels of the IRED image to estimate the distance between the camera and the IRED. In this paper, the standard deviation of the pixel grey level in the region of interest containing the IRED image is proposed as an empirical parameter to define a model for estimating camera to emitter distance. This model includes the camera exposure time, IRED radiant intensity and the distance between the camera and the IRED. An expression for the standard deviation model related to these magnitudes was also derived and calibrated using different images taken under different conditions. From this analysis, we determined the optimum parameters to ensure the best accuracy provided by this alternative. Once the model calibration had been carried out, a differential method to estimate the distance between the camera and the IRED was defined and applied, considering that the camera was aligned with the IRED. The results indicate that this method represents a useful alternative for determining the depth information. PMID:22778608

  12. Using the standard deviation of a region of interest in an image to estimate camera to emitter distance.

    PubMed

    Cano-García, Angel E; Lazaro, José Luis; Infante, Arturo; Fernández, Pedro; Pompa-Chacón, Yamilet; Espinoza, Felipe

    2012-01-01

    In this study, a camera to infrared diode (IRED) distance estimation problem was analyzed. The main objective was to define an alternative to measures depth only using the information extracted from pixel grey levels of the IRED image to estimate the distance between the camera and the IRED. In this paper, the standard deviation of the pixel grey level in the region of interest containing the IRED image is proposed as an empirical parameter to define a model for estimating camera to emitter distance. This model includes the camera exposure time, IRED radiant intensity and the distance between the camera and the IRED. An expression for the standard deviation model related to these magnitudes was also derived and calibrated using different images taken under different conditions. From this analysis, we determined the optimum parameters to ensure the best accuracy provided by this alternative. Once the model calibration had been carried out, a differential method to estimate the distance between the camera and the IRED was defined and applied, considering that the camera was aligned with the IRED. The results indicate that this method represents a useful alternative for determining the depth information.

  13. Estimate of standard deviation for a log-transformed variable using arithmetic means and standard deviations.

    PubMed

    Quan, Hui; Zhang, Ji

    2003-09-15

    Analyses of study variables are frequently based on log transformations. To calculate the power for detecting the between-treatment difference in the log scale, we need an estimate of the standard deviation of the log-transformed variable. However, in many situations a literature search only provides the arithmetic means and the corresponding standard deviations. Without individual log-transformed data to directly calculate the sample standard deviation, we need alternative methods to estimate it. This paper presents methods for estimating and constructing confidence intervals for the standard deviation of a log-transformed variable given the mean and standard deviation of the untransformed variable. It also presents methods for estimating the standard deviation of change from baseline in the log scale given the means and standard deviations of the untransformed baseline value, on-treatment value and change from baseline. Simulations and examples are provided to assess the performance of these estimates. Copyright 2003 John Wiley & Sons, Ltd.

  14. Standard Errors and Confidence Intervals of Norm Statistics for Educational and Psychological Tests.

    PubMed

    Oosterhuis, Hannah E M; van der Ark, L Andries; Sijtsma, Klaas

    2016-11-14

    Norm statistics allow for the interpretation of scores on psychological and educational tests, by relating the test score of an individual test taker to the test scores of individuals belonging to the same gender, age, or education groups, et cetera. Given the uncertainty due to sampling error, one would expect researchers to report standard errors for norm statistics. In practice, standard errors are seldom reported; they are either unavailable or derived under strong distributional assumptions that may not be realistic for test scores. We derived standard errors for four norm statistics (standard deviation, percentile ranks, stanine boundaries and Z-scores) under the mild assumption that the test scores are multinomially distributed. A simulation study showed that the standard errors were unbiased and that corresponding Wald-based confidence intervals had good coverage. Finally, we discuss the possibilities for applying the standard errors in practical test use in education and psychology. The procedure is provided via the R function check.norms, which is available in the mokken package.

  15. Reaction time as an indicator of insufficient effort: Development and validation of an embedded performance validity parameter.

    PubMed

    Stevens, Andreas; Bahlo, Simone; Licha, Christina; Liske, Benjamin; Vossler-Thies, Elisabeth

    2016-11-30

    Subnormal performance in attention tasks may result from various sources including lack of effort. In this report, the derivation and validation of a performance validity parameter for reaction time is described, using a set of malingering-indices ("Slick-criteria"), and 3 independent samples of participants (total n =893). The Slick-criteria yield an estimate of the probability of malingering based on the presence of an external incentive, evidence from neuropsychological testing, from self-report and clinical data. In study (1) a validity parameter is derived using reaction time data of a sample, composed of inpatients with recent severe brain lesions not involved in litigation and of litigants with and without brain lesion. In study (2) the validity parameter is tested in an independent sample of litigants. In study (3) the parameter is applied to an independent sample comprising cooperative and non-cooperative testees. Logistic regression analysis led to a derived validity parameter based on median reaction time and standard deviation. It performed satisfactorily in studies (2) and (3) (study 2 sensitivity=0.94, specificity=1.00; study 3 sensitivity=0.79, specificity=0.87). The findings suggest that median reaction time and standard deviation may be used as indicators of negative response bias. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  16. Effect of Temperature on the Physico-Chemical Properties of a Room Temperature Ionic Liquid (1-Methyl-3-pentylimidazolium Hexafluorophosphate) with Polyethylene Glycol Oligomer

    PubMed Central

    Wu, Tzi-Yi; Chen, Bor-Kuan; Hao, Lin; Peng, Yu-Chun; Sun, I-Wen

    2011-01-01

    A systematic study of the effect of composition on the thermo-physical properties of the binary mixtures of 1-methyl-3-pentyl imidazolium hexafluorophosphate [MPI][PF6] with poly(ethylene glycol) (PEG) [Mw = 400] is presented. The excess molar volume, refractive index deviation, viscosity deviation, and surface tension deviation values were calculated from these experimental density, ρ, refractive index, n, viscosity, η, and surface tension, γ, over the whole concentration range, respectively. The excess molar volumes are negative and continue to become increasingly negative with increasing temperature; whereas the viscosity and surface tension deviation are negative and become less negative with increasing temperature. The surface thermodynamic functions, such as surface entropy, enthalpy, as well as standard molar entropy, Parachor, and molar enthalpy of vaporization for pure ionic liquid, have been derived from the temperature dependence of the surface tension values. PMID:21731460

  17. Medical professionalism of foreign-born and foreign-trained physicians under close scrutiny: A qualitative study with stakeholders in Germany.

    PubMed

    Klingler, Corinna; Ismail, Fatiha; Marckmann, Georg; Kuehlmeyer, Katja

    2018-01-01

    Hospitals in Germany employ increasing numbers of foreign-born and foreign-trained (FB&FT) physicians. Studies have investigated how FB&FT physicians experience their professional integration into the German healthcare system, however, the perspectives of stakeholders working with and shaping the work experiences of FB&FT physicians in German hospitals have so far been neglected. This study explores relevant stakeholders' opinions and attitudes towards FB&FT physicians-which likely influence how these physicians settle in-and how these opinions were formed. We conducted a qualitative interview study with 25 stakeholders working in hospitals or in health policy development. The interviews were analyzed within a constructivist research paradigm using methods derived from Grounded Theory (situational analysis as well as open, axial and selective coding). We found that stakeholders tended to focus on problems in FB&FT physicians' work performance. Participants criticized FB&FT physicians' work for deviating from presumably shared professional standards (skill or knowledge and behavioral standards). The professional standards invoked to justify problem-focused statements comprised the definition of an ideal behavior, attitude or ability and a tolerance range that was adapted in a dynamic process. Behavior falling outside the tolerance range was criticized as unacceptable, requiring action to prevent similar deviations in the future. Furthermore, we derived three strategies (minimization, homogenization and quality management) proposed by participants to manage deviations from assumed professional standards by FB&FT physicians. We critically reflect on the social processes of evaluation and problematization and question the legitimacy of professional standards invoked. We also discuss discriminatory tendencies visible in evaluative statements of some participants as well as in some of the strategies proposed. We suggest it will be key to develop and implement better support strategies for FB&FT physicians while also addressing problematic attitudes within the receiving system to further professional integration.

  18. Medical professionalism of foreign-born and foreign-trained physicians under close scrutiny: A qualitative study with stakeholders in Germany

    PubMed Central

    Ismail, Fatiha; Marckmann, Georg; Kuehlmeyer, Katja

    2018-01-01

    Hospitals in Germany employ increasing numbers of foreign-born and foreign-trained (FB&FT) physicians. Studies have investigated how FB&FT physicians experience their professional integration into the German healthcare system, however, the perspectives of stakeholders working with and shaping the work experiences of FB&FT physicians in German hospitals have so far been neglected. This study explores relevant stakeholders’ opinions and attitudes towards FB&FT physicians—which likely influence how these physicians settle in—and how these opinions were formed. We conducted a qualitative interview study with 25 stakeholders working in hospitals or in health policy development. The interviews were analyzed within a constructivist research paradigm using methods derived from Grounded Theory (situational analysis as well as open, axial and selective coding). We found that stakeholders tended to focus on problems in FB&FT physicians’ work performance. Participants criticized FB&FT physicians’ work for deviating from presumably shared professional standards (skill or knowledge and behavioral standards). The professional standards invoked to justify problem-focused statements comprised the definition of an ideal behavior, attitude or ability and a tolerance range that was adapted in a dynamic process. Behavior falling outside the tolerance range was criticized as unacceptable, requiring action to prevent similar deviations in the future. Furthermore, we derived three strategies (minimization, homogenization and quality management) proposed by participants to manage deviations from assumed professional standards by FB&FT physicians. We critically reflect on the social processes of evaluation and problematization and question the legitimacy of professional standards invoked. We also discuss discriminatory tendencies visible in evaluative statements of some participants as well as in some of the strategies proposed. We suggest it will be key to develop and implement better support strategies for FB&FT physicians while also addressing problematic attitudes within the receiving system to further professional integration. PMID:29447259

  19. Evolution of statistical properties for a nonlinearly propagating sinusoid.

    PubMed

    Shepherd, Micah R; Gee, Kent L; Hanford, Amanda D

    2011-07-01

    The nonlinear propagation of a pure sinusoid is considered using time domain statistics. The probability density function, standard deviation, skewness, kurtosis, and crest factor are computed for both the amplitude and amplitude time derivatives as a function of distance. The amplitude statistics vary only in the postshock realm, while the amplitude derivative statistics vary rapidly in the preshock realm. The statistical analysis also suggests that the sawtooth onset distance can be considered to be earlier than previously realized. © 2011 Acoustical Society of America

  20. Poorer right ventricular systolic function and exercise capacity in women after repair of tetralogy of fallot: a sex comparison of standard deviation scores based on sex-specific reference values in healthy control subjects.

    PubMed

    Sarikouch, Samir; Boethig, Dietmar; Peters, Brigitte; Kropf, Siegfried; Dubowy, Karl-Otto; Lange, Peter; Kuehne, Titus; Haverich, Axel; Beerbaum, Philipp

    2013-11-01

    In repaired congenital heart disease, there is increasing evidence of sex differences in cardiac remodeling, but there is a lack of comparable data for specific congenital heart defects such as in repaired tetralogy of Fallot. In a prospective multicenter study, a cohort of 272 contemporary patients (158 men; mean age, 14.3±3.3 years [range, 8-20 years]) with repaired tetralogy of Fallot underwent cardiac magnetic resonance for ventricular function and metabolic exercise testing. All data were transformed to standard deviation scores according to the Lambda-Mu-Sigma method by relating individual values to their respective 50th percentile (standard deviation score, 0) in sex-specific healthy control subjects. No sex differences were observed in age at repair, type of repair conducted, or overall hemodynamic results. Relative to sex-specific controls, repaired tetralogy of Fallot in women had larger right ventricular end-systolic volumes (standard deviation scores: women, 4.35; men, 3.25; P=0.001), lower right ventricular ejection fraction (women, -2.83; men, -2.12; P=0.011), lower right ventricular muscle mass (women, 1.58; men 2.45; P=0.001), poorer peak oxygen uptake (women, -1.65; men, -1.14; P<0.001), higher VE/VCO2 (ventilation per unit of carbon dioxide production) slopes (women, 0.88; men 0.58; P=0.012), and reduced peak heart rate (women, -2.16; men -1.74; P=0.017). Left ventricular parameters did not differ between sexes. Relative to their respective sex-specific healthy control subjects, derived standard deviation scores in repaired tetralogy of Fallot suggest that women perform poorer than men in terms of right ventricular systolic function as tested by cardiac magnetic resonance and exercise capacity. This effect cannot be explained by selection bias. Further outcome data are required from longitudinal cohort studies.

  1. 7 CFR 400.204 - Notification of deviation from standards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Notification of deviation from standards. 400.204... Contract-Standards for Approval § 400.204 Notification of deviation from standards. A Contractor shall advise the Corporation immediately if the Contractor deviates from the requirements of these standards...

  2. Fast and robust standard-deviation-based method for bulk motion compensation in phase-based functional OCT.

    PubMed

    Wei, Xiang; Camino, Acner; Pi, Shaohua; Cepurna, William; Huang, David; Morrison, John C; Jia, Yali

    2018-05-01

    Phase-based optical coherence tomography (OCT), such as OCT angiography (OCTA) and Doppler OCT, is sensitive to the confounding phase shift introduced by subject bulk motion. Traditional bulk motion compensation methods are limited by their accuracy and computing cost-effectiveness. In this Letter, to the best of our knowledge, we present a novel bulk motion compensation method for phase-based functional OCT. Bulk motion associated phase shift can be directly derived by solving its equation using a standard deviation of phase-based OCTA and Doppler OCT flow signals. This method was evaluated on rodent retinal images acquired by a prototype visible light OCT and human retinal images acquired by a commercial system. The image quality and computational speed were significantly improved, compared to two conventional phase compensation methods.

  3. Comparison of low-altitude wind-shear statistics derived from measured and proposed standard wind profiles

    NASA Technical Reports Server (NTRS)

    Usry, J. W.

    1983-01-01

    Wind shear statistics were calculated for a simulated set of wind profiles based on a proposed standard wind field data base. Wind shears were grouped in altitude in altitude bands of 100 ft between 100 and 1400 ft and in wind shear increments of 0.025 knot/ft. Frequency distributions, means, and standard deviations for each altitude band were derived for the total sample were derived for both sets. It was found that frequency distributions in each altitude band for the simulated data set were more dispersed below 800 ft and less dispersed above 900 ft than those for the measured data set. Total sample frequency of occurrence for the two data sets was about equal for wind shear values between +0.075 knot/ft, but the simulated data set had significantly larger values for all wind shears outside these boundaries. It is shown that normal distribution in both data sets neither data set was normally distributed; similar results are observed from the cumulative frequency distributions.

  4. Ion chromatographic determination of sulfur in fuels

    NASA Technical Reports Server (NTRS)

    Mizisin, C. S.; Kuivinen, D. E.; Otterson, D. A.

    1978-01-01

    The sulfur content of fuels was determined using an ion chromatograph to measure the sulfate produced by a modified Parr bomb oxidation. Standard Reference Materials from the National Bureau of Standards, of approximately 0.2 + or - 0.004% sulfur, were analyzed resulting in a standard deviation no greater than 0.008. The ion chromatographic method can be applied to conventional fuels as well as shale-oil derived fuels. Other acid forming elements, such as fluorine, chlorine and nitrogen could be determined at the same time, provided that these elements have reached a suitable ionic state during the oxidation of the fuel.

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aad G.; Abbott B.; Abdallah J.

    This Letter presents a search for the Standard Model Higgs boson in the decay channel H {yields} ZZ{sup (*)} {yields} {ell}{sup +}{ell}{sup -}{ell}{prime}{sup +}{ell}{prime}{sup -}, where {ell}, {ell}{prime} = e or {mu}, using proton-proton collisions at {radical}s = 7 TeV recorded with the ATLAS detector and corresponding to an integrated luminosity of 4.8 fb{sup -1}. The four-lepton invariant mass distribution is compared with Standard Model background expectations to derive upper limits on the cross section of a Standard Model Higgs boson with a mass between 110 GeV and 600 GeV. The mass ranges 134-156 GeV, 182-233 GeV, 256-265 GeV andmore » 268-415 GeV are excluded at the 95% confidence level. The largest upward deviations from the background-only hypothesis are observed for Higgs boson masses of 125 GeV, 244 GeV and 500 GeV with local significances of 2.1, 2.2 and 2.1 standard deviations, respectively. Once the look-elsewhere effect is considered, none of these excesses are significant.« less

  6. 7 CFR 400.174 - Notification of deviation from financial standards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false Notification of deviation from financial standards... Agreement-Standards for Approval; Regulations for the 1997 and Subsequent Reinsurance Years § 400.174 Notification of deviation from financial standards. An insurer must immediately advise FCIC if it deviates from...

  7. Degrees of Freedom for Allan Deviation Estimates of Multiple Clocks

    DTIC Science & Technology

    2016-04-01

    Allan deviation . Allan deviation will be represented by σ and standard deviation will be represented by δ. In practice, when the Allan deviation of a...the Allan deviation of standard noise types. Once the number of degrees of freedom is known, an approximate confidence interval can be assigned by...measurement errors from paired difference data. We extend this approach by using the Allan deviation to estimate the error in a frequency standard

  8. Employing Sensitivity Derivatives for Robust Optimization under Uncertainty in CFD

    NASA Technical Reports Server (NTRS)

    Newman, Perry A.; Putko, Michele M.; Taylor, Arthur C., III

    2004-01-01

    A robust optimization is demonstrated on a two-dimensional inviscid airfoil problem in subsonic flow. Given uncertainties in statistically independent, random, normally distributed flow parameters (input variables), an approximate first-order statistical moment method is employed to represent the Computational Fluid Dynamics (CFD) code outputs as expected values with variances. These output quantities are used to form the objective function and constraints. The constraints are cast in probabilistic terms; that is, the probability that a constraint is satisfied is greater than or equal to some desired target probability. Gradient-based robust optimization of this stochastic problem is accomplished through use of both first and second-order sensitivity derivatives. For each robust optimization, the effect of increasing both input standard deviations and target probability of constraint satisfaction are demonstrated. This method provides a means for incorporating uncertainty when considering small deviations from input mean values.

  9. A microscopic model of the Stokes-Einstein relation in arbitrary dimension.

    PubMed

    Charbonneau, Benoit; Charbonneau, Patrick; Szamel, Grzegorz

    2018-06-14

    The Stokes-Einstein relation (SER) is one of the most robust and widely employed results from the theory of liquids. Yet sizable deviations can be observed for self-solvation, which cannot be explained by the standard hydrodynamic derivation. Here, we revisit the work of Masters and Madden [J. Chem. Phys. 74, 2450-2459 (1981)], who first solved a statistical mechanics model of the SER using the projection operator formalism. By generalizing their analysis to all spatial dimensions and to partially structured solvents, we identify a potential microscopic origin of some of these deviations. We also reproduce the SER-like result from the exact dynamics of infinite-dimensional fluids.

  10. A GPS Phase-Locked Loop Performance Metric Based on the Phase Discriminator Output

    PubMed Central

    Stevanovic, Stefan; Pervan, Boris

    2018-01-01

    We propose a novel GPS phase-lock loop (PLL) performance metric based on the standard deviation of tracking error (defined as the discriminator’s estimate of the true phase error), and explain its advantages over the popular phase jitter metric using theory, numerical simulation, and experimental results. We derive an augmented GPS phase-lock loop (PLL) linear model, which includes the effect of coherent averaging, to be used in conjunction with this proposed metric. The augmented linear model allows more accurate calculation of tracking error standard deviation in the presence of additive white Gaussian noise (AWGN) as compared to traditional linear models. The standard deviation of tracking error, with a threshold corresponding to half of the arctangent discriminator pull-in region, is shown to be a more reliable/robust measure of PLL performance under interference conditions than the phase jitter metric. In addition, the augmented linear model is shown to be valid up until this threshold, which facilitates efficient performance prediction, so that time-consuming direct simulations and costly experimental testing can be reserved for PLL designs that are much more likely to be successful. The effect of varying receiver reference oscillator quality on the tracking error metric is also considered. PMID:29351250

  11. The accuracy of ultrashort echo time MRI sequences for medical additive manufacturing

    PubMed Central

    Rijkhorst, Erik-Jan; Hofman, Mark; Forouzanfar, Tymour; Wolff, Jan

    2016-01-01

    Objectives: Additively manufactured bone models, implants and drill guides are becoming increasingly popular amongst maxillofacial surgeons and dentists. To date, such constructs are commonly manufactured using CT technology that induces ionizing radiation. Recently, ultrashort echo time (UTE) MRI sequences have been developed that allow radiation-free imaging of facial bones. The aim of the present study was to assess the feasibility of UTE MRI sequences for medical additive manufacturing (AM). Methods: Three morphologically different dry human mandibles were scanned using a CT and MRI scanner. Additionally, optical scans of all three mandibles were made to acquire a “gold standard”. All CT and MRI scans were converted into Standard Tessellation Language (STL) models and geometrically compared with the gold standard. To quantify the accuracy of the AM process, the CT, MRI and gold-standard STL models of one of the mandibles were additively manufactured, optically scanned and compared with the original gold-standard STL model. Results: Geometric differences between all three CT-derived STL models and the gold standard were <1.0 mm. All three MRI-derived STL models generally presented deviations <1.5 mm in the symphyseal and mandibular area. The AM process introduced minor deviations of <0.5 mm. Conclusions: This study demonstrates that MRI using UTE sequences is a feasible alternative to CT in generating STL models of the mandible and would therefore be suitable for surgical planning and AM. Further in vivo studies are necessary to assess the usability of UTE MRI sequences in clinical settings. PMID:26943179

  12. Middle Atmosphere Program. Handbook for MAP, Volume 5

    NASA Technical Reports Server (NTRS)

    Sechrist, C. F., Jr. (Editor)

    1982-01-01

    The variability of the stratosphere during the winter in the Northern Hemisphere is considered. Long term monthly mean 30-mbar maps are presented that include geopotential heights, temperatures, and standard deviations of 15 year averages. Latitudinal profiles of mean zonal winds and temperatures are given along with meridional time sections of derived quantities for the winters 1965/66 to 1980/81.

  13. 1 CFR 21.14 - Deviations from standard organization of the Code of Federal Regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Deviations from standard organization of the... CODIFICATION General Numbering § 21.14 Deviations from standard organization of the Code of Federal Regulations. (a) Any deviation from standard Code of Federal Regulations designations must be approved in advance...

  14. First-passage problems: A probabilistic dynamic analysis for degraded structures

    NASA Technical Reports Server (NTRS)

    Shiao, Michael C.; Chamis, Christos C.

    1990-01-01

    Structures subjected to random excitations with uncertain system parameters degraded by surrounding environments (a random time history) are studied. Methods are developed to determine the statistics of dynamic responses, such as the time-varying mean, the standard deviation, the autocorrelation functions, and the joint probability density function of any response and its derivative. Moreover, the first-passage problems with deterministic and stationary/evolutionary random barriers are evaluated. The time-varying (joint) mean crossing rate and the probability density function of the first-passage time for various random barriers are derived.

  15. Does standard deviation matter? Using "standard deviation" to quantify security of multistage testing.

    PubMed

    Wang, Chun; Zheng, Yi; Chang, Hua-Hua

    2014-01-01

    With the advent of web-based technology, online testing is becoming a mainstream mode in large-scale educational assessments. Most online tests are administered continuously in a testing window, which may post test security problems because examinees who take the test earlier may share information with those who take the test later. Researchers have proposed various statistical indices to assess the test security, and one most often used index is the average test-overlap rate, which was further generalized to the item pooling index (Chang & Zhang, 2002, 2003). These indices, however, are all defined as the means (that is, the expected proportion of common items among examinees) and they were originally proposed for computerized adaptive testing (CAT). Recently, multistage testing (MST) has become a popular alternative to CAT. The unique features of MST make it important to report not only the mean, but also the standard deviation (SD) of test overlap rate, as we advocate in this paper. The standard deviation of test overlap rate adds important information to the test security profile, because for the same mean, a large SD reflects that certain groups of examinees share more common items than other groups. In this study, we analytically derived the lower bounds of the SD under MST, with the results under CAT as a benchmark. It is shown that when the mean overlap rate is the same between MST and CAT, the SD of test overlap tends to be larger in MST. A simulation study was conducted to provide empirical evidence. We also compared the security of MST under the single-pool versus the multiple-pool designs; both analytical and simulation studies show that the non-overlapping multiple-pool design will slightly increase the security risk.

  16. Upgraded FAA Airfield Capacity Model. Volume 1. Supplemental User’s Guide

    DTIC Science & Technology

    1981-02-01

    SIGMAR (P4.0) cc 1-4 -standard deviation, in seconds, of arrival runway occupancy time (R.O.T.). SIGMAA (F4.0) cc 5-8 -standard deviation, in seconds...iI SI GMAC - The standard deviation of the time from departure clearance to start of roll. SIGMAR - The standard deviation of the arrival runway

  17. Coherent scattering of a spherical wave from an irregular surface. [antenna pattern effects

    NASA Technical Reports Server (NTRS)

    Fung, A. K.

    1983-01-01

    The scattering of a spherical wave from a rough surface using the Kirchhoff approximation is considered. An expression representing the measured coherent scattering coefficient is derived. It is shown that the sphericity of the wavefront and the antenna pattern can become an important factor in the interpretation of ground-based measurements. The condition under which the coherent scattering-coefficient expression reduces to that corresponding to a plane wave incidence is given. The condition under which the result reduces to the standard image solution is also derived. In general, the consideration of antenna pattern and sphericity is unimportant unless the surface-height standard deviation is small, i.e., unless the coherent scattering component is significant. An application of the derived coherent backscattering coefficient together with the existing incoherent scattering coefficient to interpret measurements from concrete and asphalt surfaces is shown.

  18. A Visual Model for the Variance and Standard Deviation

    ERIC Educational Resources Information Center

    Orris, J. B.

    2011-01-01

    This paper shows how the variance and standard deviation can be represented graphically by looking at each squared deviation as a graphical object--in particular, as a square. A series of displays show how the standard deviation is the size of the average square.

  19. Multi-year slant path rain fade statistics at 28.56 and 19.04 GHz for Wallops Island, Virginia

    NASA Technical Reports Server (NTRS)

    Goldhirsh, J.

    1979-01-01

    Multiyear rain fade statistics at 28.56 GHz and 19.04 GHz were compiled for the region of Wallops Island, Virginia covering the time periods, 1 April 1977 through 31 March 1978, and 1 September 1978 through 31 August 1979. The 28.56 GHz attenuations were derived by monitoring the beacon signals from the COMSTAR geosynchronous satellite, D sub 2 during the first year, and satellite, D sub 3, during the second year. Although 19.04 GHz beacons exist aboard these satellites, statistics at this frequency were predicted using the 28 GHz fade data, the measured rain rate distribution, and effective path length concepts. The prediction method used was tested against radar derived fade distributions and excellent comparisons were noted. For example, the rms deviations between the predicted and test distributions were less than or equal to 0.2dB or 4% at 19.04 GHz. The average ratio between the 28.56 GHz and 19.04 GHz fades were also derived for equal percentages of time resulting in a factor of 2.1 with a .05 standard deviation.

  20. Variability of pesticide detections and concentrations in field replicate water samples collected for the National Water-Quality Assessment Program, 1992-97

    USGS Publications Warehouse

    Martin, Jeffrey D.

    2002-01-01

    Correlation analysis indicates that for most pesticides and concentrations, pooled estimates of relative standard deviation rather than pooled estimates of standard deviation should be used to estimate variability because pooled estimates of relative standard deviation are less affected by heteroscedasticity. The 2 Variability of Pesticide Detections and Concentrations in Field Replicate Water Samples, 1992–97 median pooled relative standard deviation was calculated for all pesticides to summarize the typical variability for pesticide data collected for the NAWQA Program. The median pooled relative standard deviation was 15 percent at concentrations less than 0.01 micrograms per liter (µg/L), 13 percent at concentrations near 0.01 µg/L, 12 percent at concentrations near 0.1 µg/L, 7.9 percent at concentrations near 1 µg/L, and 2.7 percent at concentrations greater than 5 µg/L. Pooled estimates of standard deviation or relative standard deviation presented in this report are larger than estimates based on averages, medians, smooths, or regression of the individual measurements of standard deviation or relative standard deviation from field replicates. Pooled estimates, however, are the preferred method for characterizing variability because they provide unbiased estimates of the variability of the population. Assessments of variability based on standard deviation (rather than variance) underestimate the true variability of the population. Because pooled estimates of variability are larger than estimates based on other approaches, users of estimates of variability must be cognizant of the approach used to obtain the estimate and must use caution in the comparison of estimates based on different approaches.

  1. Basic life support: evaluation of learning using simulation and immediate feedback devices1.

    PubMed

    Tobase, Lucia; Peres, Heloisa Helena Ciqueto; Tomazini, Edenir Aparecida Sartorelli; Teodoro, Simone Valentim; Ramos, Meire Bruna; Polastri, Thatiane Facholi

    2017-10-30

    to evaluate students' learning in an online course on basic life support with immediate feedback devices, during a simulation of care during cardiorespiratory arrest. a quasi-experimental study, using a before-and-after design. An online course on basic life support was developed and administered to participants, as an educational intervention. Theoretical learning was evaluated by means of a pre- and post-test and, to verify the practice, simulation with immediate feedback devices was used. there were 62 participants, 87% female, 90% in the first and second year of college, with a mean age of 21.47 (standard deviation 2.39). With a 95% confidence level, the mean scores in the pre-test were 6.4 (standard deviation 1.61), and 9.3 in the post-test (standard deviation 0.82, p <0.001); in practice, 9.1 (standard deviation 0.95) with performance equivalent to basic cardiopulmonary resuscitation, according to the feedback device; 43.7 (standard deviation 26.86) mean duration of the compression cycle by second of 20.5 (standard deviation 9.47); number of compressions 167.2 (standard deviation 57.06); depth of compressions of 48.1 millimeter (standard deviation 10.49); volume of ventilation 742.7 (standard deviation 301.12); flow fraction percentage of 40.3 (standard deviation 10.03). the online course contributed to learning of basic life support. In view of the need for technological innovations in teaching and systematization of cardiopulmonary resuscitation, simulation and feedback devices are resources that favor learning and performance awareness in performing the maneuvers.

  2. A general and fast scoring function for protein-ligand interactions: a simplified potential approach.

    PubMed

    Muegge, I; Martin, Y C

    1999-03-11

    A fast, simplified potential-based approach is presented that estimates the protein-ligand binding affinity based on the given 3D structure of a protein-ligand complex. This general, knowledge-based approach exploits structural information of known protein-ligand complexes extracted from the Brookhaven Protein Data Bank and converts it into distance-dependent Helmholtz free interaction energies of protein-ligand atom pairs (potentials of mean force, PMF). The definition of an appropriate reference state and the introduction of a correction term accounting for the volume taken by the ligand were found to be crucial for deriving the relevant interaction potentials that treat solvation and entropic contributions implicitly. A significant correlation between experimental binding affinities and computed score was found for sets of diverse protein-ligand complexes and for sets of different ligands bound to the same target. For 77 protein-ligand complexes taken from the Brookhaven Protein Data Bank, the calculated score showed a standard deviation from observed binding affinities of 1.8 log Ki units and an R2 value of 0.61. The best results were obtained for the subset of 16 serine protease complexes with a standard deviation of 1.0 log Ki unit and an R2 value of 0.86. A set of 33 inhibitors modeled into a crystal structure of HIV-1 protease yielded a standard deviation of 0.8 log Ki units from measured inhibition constants and an R2 value of 0.74. In contrast to empirical scoring functions that show similar or sometimes better correlation with observed binding affinities, our method does not involve deriving specific parameters that fit the observed binding affinities of protein-ligand complexes of a given training set. We compared the performance of the PMF score, Böhm's score (LUDI), and the SMOG score for eight different test sets of protein-ligand complexes. It was found that for the majority of test sets the PMF score performs best. The strength of the new approach presented here lies in its generality as no knowledge about measured binding affinities is needed to derive atomic interaction potentials. The use of the new scoring function in docking studies is outlined.

  3. Constraining the noncommutative spectral action via astrophysical observations.

    PubMed

    Nelson, William; Ochoa, Joseph; Sakellariadou, Mairi

    2010-09-03

    The noncommutative spectral action extends our familiar notion of commutative spaces, using the data encoded in a spectral triple on an almost commutative space. Varying a rather simple action, one can derive all of the standard model of particle physics in this setting, in addition to a modified version of Einstein-Hilbert gravity. In this Letter we use observations of pulsar timings, assuming that no deviation from general relativity has been observed, to constrain the gravitational sector of this theory. While the bounds on the coupling constants remain rather weak, they are comparable to existing bounds on deviations from general relativity in other settings and are likely to be further constrained by future observations.

  4. Using an external gating signal to estimate noise in PET with an emphasis on tracer avid tumors

    NASA Astrophysics Data System (ADS)

    Schmidtlein, C. R.; Beattie, B. J.; Bailey, D. L.; Akhurst, T. J.; Wang, W.; Gönen, M.; Kirov, A. S.; Humm, J. L.

    2010-10-01

    The purpose of this study is to establish and validate a methodology for estimating the standard deviation of voxels with large activity concentrations within a PET image using replicate imaging that is immediately available for use in the clinic. To do this, ensembles of voxels in the averaged replicate images were compared to the corresponding ensembles in images derived from summed sinograms. In addition, the replicate imaging noise estimate was compared to a noise estimate based on an ensemble of voxels within a region. To make this comparison two phantoms were used. The first phantom was a seven-chamber phantom constructed of 1 liter plastic bottles. Each chamber of this phantom was filled with a different activity concentration relative to the lowest activity concentration with ratios of 1:1, 1:1, 2:1, 2:1, 4:1, 8:1 and 16:1. The second phantom was a GE Well-Counter phantom. These phantoms were imaged and reconstructed on a GE DSTE PET/CT scanner with 2D and 3D reprojection filtered backprojection (FBP), and with 2D- and 3D-ordered subset expectation maximization (OSEM). A series of tests were applied to the resulting images that showed that the region and replicate imaging methods for estimating standard deviation were equivalent for backprojection reconstructions. Furthermore, the noise properties of the FBP algorithms allowed scaling the replicate estimates of the standard deviation by a factor of 1/\\sqrt{N}, where N is the number of replicate images, to obtain the standard deviation of the full data image. This was not the case for OSEM image reconstruction. Due to nonlinearity of the OSEM algorithm, the noise is shown to be both position and activity concentration dependent in such a way that no simple scaling factor can be used to extrapolate noise as a function of counts. The use of the Well-Counter phantom contributed to the development of a heuristic extrapolation of the noise as a function of radius in FBP. In addition, the signal-to-noise ratio for high uptake objects was confirmed to be higher with backprojection image reconstruction methods. These techniques were applied to several patient data sets acquired in either 2D or 3D mode, with 18F (FLT and FDG). Images of the standard deviation and signal-to-noise ratios were constructed and the standard deviations of the tumors' uptake were determined. Finally, a radial noise extrapolation relationship deduced in this paper was applied to patient data.

  5. Multi-technique comparison of troposphere zenith delays and gradients during CONT08

    NASA Astrophysics Data System (ADS)

    Teke, Kamil; Böhm, Johannes; Nilsson, Tobias; Schuh, Harald; Steigenberger, Peter; Dach, Rolf; Heinkelmann, Robert; Willis, Pascal; Haas, Rüdiger; García-Espada, Susana; Hobiger, Thomas; Ichikawa, Ryuichi; Shimizu, Shingo

    2011-07-01

    CONT08 was a 15 days campaign of continuous Very Long Baseline Interferometry (VLBI) sessions during the second half of August 2008 carried out by the International VLBI Service for Geodesy and Astrometry (IVS). In this study, VLBI estimates of troposphere zenith total delays (ZTD) and gradients during CONT08 were compared with those derived from observations with the Global Positioning System (GPS), Doppler Orbitography and Radiopositioning Integrated by Satellite (DORIS), and water vapor radiometers (WVR) co-located with the VLBI radio telescopes. Similar geophysical models were used for the analysis of the space geodetic data, whereas the parameterization for the least-squares adjustment of the space geodetic techniques was optimized for each technique. In addition to space geodetic techniques and WVR, ZTD and gradients from numerical weather models (NWM) were used from the European Centre for Medium-Range Weather Forecasts (ECMWF) (all sites), the Japan Meteorological Agency (JMA) and Cloud Resolving Storm Simulator (CReSS) (Tsukuba), and the High Resolution Limited Area Model (HIRLAM) (European sites). Biases, standard deviations, and correlation coefficients were computed between the troposphere estimates of the various techniques for all eleven CONT08 co-located sites. ZTD from space geodetic techniques generally agree at the sub-centimetre level during CONT08, and—as expected—the best agreement is found for intra-technique comparisons: between the Vienna VLBI Software and the combined IVS solutions as well as between the Center for Orbit Determination (CODE) solution and an IGS PPP time series; both intra-technique comparisons are with standard deviations of about 3-6 mm. The best inter space geodetic technique agreement of ZTD during CONT08 is found between the combined IVS and the IGS solutions with a mean standard deviation of about 6 mm over all sites, whereas the agreement with numerical weather models is between 6 and 20 mm. The standard deviations are generally larger at low latitude sites because of higher humidity, and the latter is also the reason why the standard deviations are larger at northern hemisphere stations during CONT08 in comparison to CONT02 which was observed in October 2002. The assessment of the troposphere gradients from the different techniques is not as clear because of different time intervals, different estimation properties, or different observables. However, the best inter-technique agreement is found between the IVS combined gradients and the GPS solutions with standard deviations between 0.2 and 0.7 mm.

  6. Feasibility of coupling a thermal/optical carbon analyzer to a quadrupole mass spectrometer for enhanced PM2.5 speciation.

    PubMed

    Riggio, Gustavo M; Chow, Judith C; Cropper, Paul M; Wang, Xiaoliang; Yatavelli, Reddy L N; Yang, Xufei; Watson, John G

    2018-05-01

    A thermal/optical carbon analyzer (TOA), normally used for quantification of organic carbon (OC) and elemental carbon (EC) in PM 2.5 (fine particulate matter) speciation networks, was adapted to direct thermally evolved gases to an electron impact quadrupole mass spectrometer (QMS), creating a TOA-QMS. This approach produces spectra similar to those obtained by the Aerodyne aerosol mass spectrometer (AMS), but the ratios of the mass to charge (m/z) signals differ and must be remeasured using laboratory-generated standards. Linear relationships are found between TOA-QMS signals and ammonium (NH 4 + ), nitrate (NO 3 - ), and sulfate (SO 4 2- ) standards. For ambient samples, however, positive deviations are found for SO 4 2- , compensated by negative deviations for NO 3 - , at higher concentrations. This indicates the utility of mixed-compound standards for calibration or separate calibration curves for low and high ion concentrations. The sum of the QMS signals across all m/z after removal of the NH 4 + , NO 3 - , and SO 4 2- signals was highly correlated with the carbon content of oxalic acid (C₂H₂O₄) standards. For ambient samples, the OC derived from the TOA-QMS method was the same as the OC derived from the standard IMPROVE_A TOA method. This method has the potential to reduce complexity and costs for speciation networks, especially for highly polluted urban areas such as those in Asia and Africa. Ammonium, nitrate, and sulfate can be quantified by the same thermal evolution analysis applied to organic and elemental carbon. This holds the potential to replace multiple parallel filter samples and separate laboratory analyses with a single filter and a single analysis to account for a large portion of the PM 2.5 mass concentration.

  7. Accuracy of the HST Standard Astrometric Catalogs w.r.t. Gaia

    NASA Astrophysics Data System (ADS)

    Kozhurina-Platais, V.; Grogin, N.; Sabbi, E.

    2018-02-01

    The goal of astrometric calibration of the HST ACS/WFC and WFC3/UVIS imaging instruments is to provide a coordinate system free of distortion to the precision level of 0.1 pixel 4-5 mas or better. This astrometric calibration is based on two HST astrometric standard fields in the vicinity of the globular clusters, 47 Tuc and omega Cen, respectively. The derived calibration of the geometric distortion is assumed to be accurate down to 2-3 mas. Is this accuracy in agreement with the true value? Now, with the access to globally accurate positions from the first Gaia data release (DR1), we found that there are measurable offsets, rotation, scale and other deviations of distortion parameters in two HST standard astrometric catalogs. These deviations from the distortion-free and properly aligned coordinate system should be accounted and corrected for, so that the high precision HST positions are free of any systematic errors. We also found that the precision of the HST pixel coordinates is substantially better than the accuracy listed in the Gaia DR1. Therefore, in order to finalize the components of distortion in the HST standard catalogs, the next release of Gaia data is needed.

  8. Fluctuation-dissipation relation and stationary distribution of an exactly solvable many-particle model for active biomatter far from equilibrium.

    PubMed

    Netz, Roland R

    2018-05-14

    An exactly solvable, Hamiltonian-based model of many massive particles that are coupled by harmonic potentials and driven by stochastic non-equilibrium forces is introduced. The stationary distribution and the fluctuation-dissipation relation are derived in closed form for the general non-equilibrium case. Deviations from equilibrium are on one hand characterized by the difference of the obtained stationary distribution from the Boltzmann distribution; this is possible because the model derives from a particle Hamiltonian. On the other hand, the difference between the obtained non-equilibrium fluctuation-dissipation relation and the standard equilibrium fluctuation-dissipation theorem allows us to quantify non-equilibrium in an alternative fashion. Both indicators of non-equilibrium behavior, i.e., deviations from the Boltzmann distribution and deviations from the equilibrium fluctuation-dissipation theorem, can be expressed in terms of a single non-equilibrium parameter α that involves the ratio of friction coefficients and random force strengths. The concept of a non-equilibrium effective temperature, which can be defined by the relation between fluctuations and the dissipation, is by comparison with the exactly derived stationary distribution shown not to hold, even if the effective temperature is made frequency dependent. The analysis is not confined to close-to-equilibrium situations but rather is exact and thus holds for arbitrarily large deviations from equilibrium. Also, the suggested harmonic model can be obtained from non-linear mechanical network systems by an expansion in terms of suitably chosen deviatory coordinates; the obtained results should thus be quite general. This is demonstrated by comparison of the derived non-equilibrium fluctuation dissipation relation with experimental data on actin networks that are driven out of equilibrium by energy-consuming protein motors. The comparison is excellent and allows us to extract the non-equilibrium parameter α from experimental spectral response and fluctuation data.

  9. Fluctuation-dissipation relation and stationary distribution of an exactly solvable many-particle model for active biomatter far from equilibrium

    NASA Astrophysics Data System (ADS)

    Netz, Roland R.

    2018-05-01

    An exactly solvable, Hamiltonian-based model of many massive particles that are coupled by harmonic potentials and driven by stochastic non-equilibrium forces is introduced. The stationary distribution and the fluctuation-dissipation relation are derived in closed form for the general non-equilibrium case. Deviations from equilibrium are on one hand characterized by the difference of the obtained stationary distribution from the Boltzmann distribution; this is possible because the model derives from a particle Hamiltonian. On the other hand, the difference between the obtained non-equilibrium fluctuation-dissipation relation and the standard equilibrium fluctuation-dissipation theorem allows us to quantify non-equilibrium in an alternative fashion. Both indicators of non-equilibrium behavior, i.e., deviations from the Boltzmann distribution and deviations from the equilibrium fluctuation-dissipation theorem, can be expressed in terms of a single non-equilibrium parameter α that involves the ratio of friction coefficients and random force strengths. The concept of a non-equilibrium effective temperature, which can be defined by the relation between fluctuations and the dissipation, is by comparison with the exactly derived stationary distribution shown not to hold, even if the effective temperature is made frequency dependent. The analysis is not confined to close-to-equilibrium situations but rather is exact and thus holds for arbitrarily large deviations from equilibrium. Also, the suggested harmonic model can be obtained from non-linear mechanical network systems by an expansion in terms of suitably chosen deviatory coordinates; the obtained results should thus be quite general. This is demonstrated by comparison of the derived non-equilibrium fluctuation dissipation relation with experimental data on actin networks that are driven out of equilibrium by energy-consuming protein motors. The comparison is excellent and allows us to extract the non-equilibrium parameter α from experimental spectral response and fluctuation data.

  10. Heavy Ozone Enrichments from ATMOS Infrared Solar Spectra

    NASA Technical Reports Server (NTRS)

    Irion, F. W.; Gunson, M. R.; Rinsland, C. P.; Yung, Y. L.; Abrams, M. C.; Chang, A. Y.; Goldman, A.

    1996-01-01

    Vertical enrichment profiles of stratospheric O-16O-16O-18 and O-16O-18O-16 (hereafter referred to as (668)O3 and (686)O3 respectively) have been derived from space-based solar occultation spectra recorded at 0.01 cm(exp-1) resolution by the ATMOS (Atmospheric Trace MOlecule Spectroscopy) Fourier transform infrared (FTIR) spectrometer. The observations, made during the Spacelab 3 and ATLAS-1, -2, and -3 shuttle missions, cover polar, mid-latitude and tropical regions between 26 to 2.6 mb inclusive (approximately 25 to 41 km). Average enrichments, weighted by molecular (48)O3 density, of (15 +/- 6)% were found for (668)O3 and (10 +/- 7)% for (686)O3. Defining the mixing ratio of (50)O3 as the sum of those for (668)O3 and (686)O3, an enrichment of (13 plus or minus 5)% was found for (50)O3 (1 sigma standard deviation). No latitudinal or vertical gradients were found outside this standard deviation. From a series of ground-based measurements by the ATMOS instrument at Table Mountain, California (34.4 deg N), an average total column (668)O3 enrichment of (17 +/- 4)% (1 sigma standard deviation) was determined, with no significant seasonal variation discernable. Possible biases in the spectral intensities that affect the determination of absolute enrichments are discussed.

  11. How do we assign punishment? The impact of minimal and maximal standards on the evaluation of deviants.

    PubMed

    Kessler, Thomas; Neumann, Jörg; Mummendey, Amélie; Berthold, Anne; Schubert, Thomas; Waldzus, Sven

    2010-09-01

    To explain the determinants of negative behavior toward deviants (e.g., punishment), this article examines how people evaluate others on the basis of two types of standards: minimal and maximal. Minimal standards focus on an absolute cutoff point for appropriate behavior; accordingly, the evaluation of others varies dichotomously between acceptable or unacceptable. Maximal standards focus on the degree of deviation from that standard; accordingly, the evaluation of others varies gradually from positive to less positive. This framework leads to the prediction that violation of minimal standards should elicit punishment regardless of the degree of deviation, whereas punishment in response to violations of maximal standards should depend on the degree of deviation. Four studies assessed or manipulated the type of standard and degree of deviation displayed by a target. Results consistently showed the expected interaction between type of standard (minimal and maximal) and degree of deviation on punishment behavior.

  12. Background derivation and image flattening: getimages

    NASA Astrophysics Data System (ADS)

    Men'shchikov, A.

    2017-11-01

    Modern high-resolution images obtained with space observatories display extremely strong intensity variations across images on all spatial scales. Source extraction in such images with methods based on global thresholding may bring unacceptably large numbers of spurious sources in bright areas while failing to detect sources in low-background or low-noise areas. It would be highly beneficial to subtract background and equalize the levels of small-scale fluctuations in the images before extracting sources or filaments. This paper describes getimages, a new method of background derivation and image flattening. It is based on median filtering with sliding windows that correspond to a range of spatial scales from the observational beam size up to a maximum structure width Xλ. The latter is a single free parameter of getimages that can be evaluated manually from the observed image ℐλ. The median filtering algorithm provides a background image \\tilde{Bλ} for structures of all widths below Xλ. The same median filtering procedure applied to an image of standard deviations 𝓓λ derived from a background-subtracted image \\tilde{Sλ} results in a flattening image \\tilde{Fλ}. Finally, a flattened detection image I{λD} = \\tilde{Sλ}/\\tilde{Fλ} is computed, whose standard deviations are uniform outside sources and filaments. Detecting sources in such greatly simplified images results in much cleaner extractions that are more complete and reliable. As a bonus, getimages reduces various observational and map-making artifacts and equalizes noise levels between independent tiles of mosaicked images.

  13. Radial gradient and radial deviation radiomic features from pre-surgical CT scans are associated with survival among lung adenocarcinoma patients.

    PubMed

    Tunali, Ilke; Stringfield, Olya; Guvenis, Albert; Wang, Hua; Liu, Ying; Balagurunathan, Yoganand; Lambin, Philippe; Gillies, Robert J; Schabath, Matthew B

    2017-11-10

    The goal of this study was to extract features from radial deviation and radial gradient maps which were derived from thoracic CT scans of patients diagnosed with lung adenocarcinoma and assess whether these features are associated with overall survival. We used two independent cohorts from different institutions for training (n= 61) and test (n= 47) and focused our analyses on features that were non-redundant and highly reproducible. To reduce the number of features and covariates into a single parsimonious model, a backward elimination approach was applied. Out of 48 features that were extracted, 31 were eliminated because they were not reproducible or were redundant. We considered 17 features for statistical analysis and identified a final model containing the two most highly informative features that were associated with lung cancer survival. One of the two features, radial deviation outside-border separation standard deviation, was replicated in a test cohort exhibiting a statistically significant association with lung cancer survival (multivariable hazard ratio = 0.40; 95% confidence interval 0.17-0.97). Additionally, we explored the biological underpinnings of these features and found radial gradient and radial deviation image features were significantly associated with semantic radiological features.

  14. Estimation of time-series properties of gourd observed solar irradiance data using cloud properties derived from satellite observations

    NASA Astrophysics Data System (ADS)

    Watanabe, T.; Nohara, D.

    2017-12-01

    The shorter temporal scale variation in the downward solar irradiance at the ground level (DSI) is not understood well because researches in the shorter-scale variation in the DSI is based on the ground observation and ground observation stations are located coarsely. Use of dataset derived from satellite observation will overcome such defect. DSI data and MODIS cloud properties product are analyzed simultaneously. Three metrics: mean, standard deviation and sample entropy, are used to evaluate time-series properties of the DSI. Three metrics are computed from two-hours time-series centered at the observation time of MODIS over the ground observation stations. We apply the regression methods to design prediction models of each three metrics from cloud properties. The validation of the model accuracy show that mean and standard deviation are predicted with a higher degree of accuracy and that the accuracy of prediction of sample entropy, which represents the complexity of time-series, is not high. One of causes of lower prediction skill of sample entropy is the resolution of the MODIS cloud properties. Higher sample entropy is corresponding to the rapid fluctuation, which is caused by the small and unordered cloud. It seems that such clouds isn't retrieved well.

  15. A novel quadruplex real-time PCR method for simultaneous detection of Cry2Ae and two genetically modified cotton events (GHB119 and T304-40).

    PubMed

    Li, Xiang; Wang, Xiuxiu; Yang, Jielin; Liu, Yueming; He, Yuping; Pan, Liangwen

    2014-05-16

    To date, over 150 genetically modified (GM) crops are widely cultivated. To comply with regulations developed for genetically modified organisms (GMOs), including labeling policies, many detection methods for GMO identification and quantification have been developed. To detect the entrance and exit of unauthorized GM crop events in China, we developed a novel quadruplex real-time PCR method for simultaneous detection and quantification of GM cotton events GHB119 and T304-40 in cotton-derived products (based on the 5'-flanking sequence) and the insect-resistance gene Cry2Ae. The limit of detection was 10 copies for GHB119 and Cry2Ae and 25 copies for T304-40. The limit of quantification was 25 copies for GHB119 and Cry2Ae and 50 copies for T304-40. Moreover, low bias and acceptable standard deviation and relative standard deviation values were obtained in quantification analysis of six blind samples containing different GHB119 and T304-40 ingredients. The developed quadruplex quantitative method could be used for quantitative detection of two GM cotton events (GHB119 and T304-40) and Cry2Ae gene ingredient in cotton derived products.

  16. A novel quadruplex real-time PCR method for simultaneous detection of Cry2Ae and two genetically modified cotton events (GHB119 and T304-40)

    PubMed Central

    2014-01-01

    Background To date, over 150 genetically modified (GM) crops are widely cultivated. To comply with regulations developed for genetically modified organisms (GMOs), including labeling policies, many detection methods for GMO identification and quantification have been developed. Results To detect the entrance and exit of unauthorized GM crop events in China, we developed a novel quadruplex real-time PCR method for simultaneous detection and quantification of GM cotton events GHB119 and T304-40 in cotton-derived products (based on the 5′-flanking sequence) and the insect-resistance gene Cry2Ae. The limit of detection was 10 copies for GHB119 and Cry2Ae and 25 copies for T304-40. The limit of quantification was 25 copies for GHB119 and Cry2Ae and 50 copies for T304-40. Moreover, low bias and acceptable standard deviation and relative standard deviation values were obtained in quantification analysis of six blind samples containing different GHB119 and T304-40 ingredients. Conclusions The developed quadruplex quantitative method could be used for quantitative detection of two GM cotton events (GHB119 and T304-40) and Cry2Ae gene ingredient in cotton derived products. PMID:24884946

  17. Joint US Navy/US Air Force climatic study of the upper atmosphere. Volume 1: January

    NASA Astrophysics Data System (ADS)

    Changery, Michael J.; Williams, Claude N.; Dickenson, Michael L.; Wallace, Brian L.

    1989-07-01

    The upper atmosphere was studied based on 1980 to 1985 twice daily gridded analyses produced by the European Centre for Medium Range Weather Forecasts. This volume is for the month of January. Included are global analyses of: (1) Mean temperature standard deviation; (2) Mean geopotential height standard deviation; (3) Mean density standard deviation; (4) Mean density standard deviation (all for 13 levels - 1000, 850, 700, 500, 400, 300, 250, 200, 150, 100, 70, 50, 30 mb); (5) Mean dew point standard deviation for the 13 levels; and (6) Jet stream at levels 500 through 30 mb. Also included are global 5 degree grid point wind roses for the 13 pressure levels.

  18. Implications of Higgs searches on the four-generation standard model.

    PubMed

    Kuflik, Eric; Nir, Yosef; Volansky, Tomer

    2013-03-01

    Within the four-generation standard model, the Higgs couplings to gluons and to photons deviate in a significant way from the predictions of the three-generation standard model. As a consequence, large departures in several Higgs production and decay channels are expected. Recent Higgs search results, presented by ATLAS, CMS, and CDF, hint on the existence of a Higgs boson with a mass around 125 GeV. Using these results and assuming such a Higgs boson, we derive exclusion limits on the four-generation standard model. For m(H)=125 GeV, the model is excluded above 99.95% confidence level. For 124.5 GeV≤m(H)≤127.5 GeV, an exclusion limit above 99% confidence level is found.

  19. [Detection of methyl carbamate and ethyl carbamate in yellow rice wine by gas chromatography-mass spectrometry].

    PubMed

    Wu, Ping-gu; Ma, Bing-jie; Wang, Li-yuan; Shen, Xiang-hong; Zhang, Jing; Tan, Ying; Jiang, Wei

    2013-11-01

    To establish the method of simultaneous determination of methylcarbamate (MC) and ethylcarbamate (EC) in yellow rice wine by gas chromatography-mass spectrometry (GC/MS). MC and EC in yellow rice wine were derived by 9-xanthydrol, and then the derivants were detected by GC/MS; and quantitatively analyzed by D5-EC isotope internal standard method. The linearity of MC and EC ranged from 2.0 µg/L to 400.0 µg/L, with correlation coefficients at 0.998 and 0.999, respectively. The limits of quantitation (LOQ) and detection (LOD) were 0.67 and 2.0 µg/kg. When MC and EC were added in yellow rice wine at the range of 2.0-300.0 µg/kg, the intraday average recovery rate was 78.8%-102.3%, relative standard deviation was 3.2%-11.6%; interday average recovery rate was 75.4%-101.3%, relative standard deviation was 3.8%-13.4%. 20 samples of yellow rice wine from supermarket were detected using this method, the contents of MC were in the range of ND (no detected) to 1.2 µg/kg, the detection rate was 6% (3/20), the contents of EC in the range of 18.6 µg/kg to 432.3 µg/kg, with the average level at 135.2 µg/kg. The method is simple, rapid and useful for simultaneous determination of MC and EC in yellow rice wine.

  20. Comparing Standard Deviation Effects across Contexts

    ERIC Educational Resources Information Center

    Ost, Ben; Gangopadhyaya, Anuj; Schiman, Jeffrey C.

    2017-01-01

    Studies using tests scores as the dependent variable often report point estimates in student standard deviation units. We note that a standard deviation is not a standard unit of measurement since the distribution of test scores can vary across contexts. As such, researchers should be cautious when interpreting differences in the numerical size of…

  1. Evolving geometrical heterogeneities of fault trace data

    NASA Astrophysics Data System (ADS)

    Wechsler, Neta; Ben-Zion, Yehuda; Christofferson, Shari

    2010-08-01

    We perform a systematic comparative analysis of geometrical fault zone heterogeneities using derived measures from digitized fault maps that are not very sensitive to mapping resolution. We employ the digital GIS map of California faults (version 2.0) and analyse the surface traces of active strike-slip fault zones with evidence of Quaternary and historic movements. Each fault zone is broken into segments that are defined as a continuous length of fault bounded by changes of angle larger than 1°. Measurements of the orientations and lengths of fault zone segments are used to calculate the mean direction and misalignment of each fault zone from the local plate motion direction, and to define several quantities that represent the fault zone disorder. These include circular standard deviation and circular standard error of segments, orientation of long and short segments with respect to the mean direction, and normal separation distances of fault segments. We examine the correlations between various calculated parameters of fault zone disorder and the following three potential controlling variables: cumulative slip, slip rate and fault zone misalignment from the plate motion direction. The analysis indicates that the circular standard deviation and circular standard error of segments decrease overall with increasing cumulative slip and increasing slip rate of the fault zones. The results imply that the circular standard deviation and error, quantifying the range or dispersion in the data, provide effective measures of the fault zone disorder, and that the cumulative slip and slip rate (or more generally slip rate normalized by healing rate) represent the fault zone maturity. The fault zone misalignment from plate motion direction does not seem to play a major role in controlling the fault trace heterogeneities. The frequency-size statistics of fault segment lengths can be fitted well by an exponential function over the entire range of observations.

  2. Blood pressure variability in man: its relation to high blood pressure, age and baroreflex sensitivity.

    PubMed

    Mancia, G; Ferrari, A; Gregorini, L; Parati, G; Pomidossi, G; Bertinieri, G; Grassi, G; Zanchetti, A

    1980-12-01

    1. Intra-arterial blood pressure and heart rate were recorded for 24 h in ambulant hospitalized patients of variable age who had normal blood pressure or essential hypertension. Mean 24 h values, standard deviations and variation coefficient were obtained as the averages of values separately analysed for 48 consecutive half-hour periods. 2. In older subjects standard deviation and variation coefficient for mean arterial pressure were greater than in younger subjects with similar pressure values, whereas standard deviation and variation coefficient for mean arterial pressure were greater than in younger subjects with similar pressure values, whereas standard deviation aations and variation coefficient were obtained as the averages of values separately analysed for 48 consecurive half-hour periods. 2. In older subjects standard deviation and variation coefficient for mean arterial pressure were greater than in younger subjects with similar pressure values, whereas standard deviation and variation coefficient for heart rate were smaller. 3. In hypertensive subjects standard deviation for mean arterial pressure was greater than in normotensive subjects of similar ages, but this was not the case for variation coefficient, which was slightly smaller in the former than in the latter group. Normotensive and hypertensive subjects showed no difference in standard deviation and variation coefficient for heart rate. 4. In both normotensive and hypertensive subjects standard deviation and even more so variation coefficient were slightly or not related to arterial baroreflex sensitivity as measured by various methods (phenylephrine, neck suction etc.). 5. It is concluded that blood pressure variability increases and heart rate variability decreases with age, but that changes in variability are not so obvious in hypertension. Also, differences in variability among subjects are only marginally explained by differences in baroreflex function.

  3. Joint US Navy/US Air Force climatic study of the upper atmosphere. Volume 7: July

    NASA Astrophysics Data System (ADS)

    Changery, Michael J.; Williams, Claude N.; Dickenson, Michael L.; Wallace, Brian L.

    1989-07-01

    The upper atmosphere was studied based on 1980 to 1985 twice daily gridded analysis produced by the European Centre for Medium Range Weather Forecasts. This volume is for the month of July. Included are global analyses of: (1) Mean temperature/standard deviation; (2) Mean geopotential height/standard deviation; (3) Mean density/standard deviation; (4) Height and vector standard deviation (all at 13 pressure levels - 1000, 850, 700, 500, 400, 300, 250, 200, 150, 100, 70, 50, 30 mb); (5) Mean dew point standard deviation at levels 1000 through 30 mb; and (6) Jet stream at levels 500 through 30 mb. Also included are global 5 degree grid point wind roses for the 13 pressure levels.

  4. Joint US Navy/US Air Force climatic study of the upper atmosphere. Volume 10: October

    NASA Astrophysics Data System (ADS)

    Changery, Michael J.; Williams, Claude N.; Dickenson, Michael L.; Wallace, Brian L.

    1989-07-01

    The upper atmosphere was studied based on 1980 to 1985 twice daily gridded analysis produced by the European Centre for Medium Range Weather Forecasts. This volume is for the month of October. Included are global analyses of: (1) Mean temperature/standard deviation; (2) Mean geopotential height/standard deviation; (3) Mean density/standard deviation; (4) Height and vector standard deviation (all at 13 pressure levels - 1000, 850, 700, 500, 400, 300, 250, 200, 150, 100, 70, 50, 30 mb); (5) Mean dew point/standard deviation at levels 1000 through 30 mb; and (6) Jet stream at levels 500 through 30 mb. Also included are global 5 degree grid point wind roses for the 13 pressure levels.

  5. Joint US Navy/US Air Force climatic study of the upper atmosphere. Volume 3: March

    NASA Astrophysics Data System (ADS)

    Changery, Michael J.; Williams, Claude N.; Dickenson, Michael L.; Wallace, Brian L.

    1989-11-01

    The upper atmosphere was studied based on 1980 to 1985 twice daily gridded analysis produced by the European Centre for Medium Range Weather Forecasts. This volume is for the month of March. Included are global analyses of: (1) Mean Temperature Standard Deviation; (2) Mean Geopotential Height Standard Deviation; (3) Mean Density Standard Deviation; (4) Height and Vector Standard Deviation (all for 13 pressure levels - 1000, 850, 700, 500, 400, 300, 250, 200, 150, 100, 70, 50, 30 mb); (5) Mean Dew Point Standard Deviation for levels 1000 through 30 mb; and (6) Jet stream for levels 500 through 30 mb. Also included are global 5 degree grid point wind roses for the 13 pressure levels.

  6. Joint US Navy/US Air Force climatic study of the upper atmosphere. Volume 2: February

    NASA Astrophysics Data System (ADS)

    Changery, Michael J.; Williams, Claude N.; Dickenson, Michael L.; Wallace, Brian L.

    1989-09-01

    The upper atmosphere was studied based on 1980 to 1985 twice daily gridded analyses produced by the European Centre for Medium Range Weather Forecasts. This volume is for the month of February. Included are global analyses of: (1) Mean temperature standard deviation; (2) Mean geopotential height standard deviation; (3) Mean density standard deviation; (4) Height and vector standard deviation (all for 13 pressure levels - 1000, 850, 700, 500, 400, 300, 250, 200, 150, 100, 70, 50, 30 mb); (5) Mean dew point standard deviation for the 13 levels; and (6) Jet stream for levels 500 through 30 mb. Also included are global 5 degree grid point wind roses for the 13 pressure levels.

  7. Joint US Navy/US Air Force climatic study of the upper atmosphere. Volume 4: April

    NASA Astrophysics Data System (ADS)

    Changery, Michael J.; Williams, Claude N.; Dickenson, Michael L.; Wallace, Brian L.

    1989-07-01

    The upper atmosphere was studied based on 1980 to 1985 twice daily gridded analyses produced by the European Centre for Medium Range Weather Forecasts. This volume is for the month of April. Included are global analyses of: (1) Mean temperature standard deviation; (2) Mean geopotential height standard deviation; (3) Mean density standard deviation; (4) Height and vector standard deviation (all for 13 pressure levels - 1000, 850, 700, 500, 400, 300, 250, 200, 150, 100, 70, 50, 30 mb); (5) Mean dew point standard deviation for the 13 levels; and (6) Jet stream for levels 500 through 30 mb. Also included are global 5 degree grid point wind roses for the 13 pressure levels.

  8. Precision analysis for standard deviation measurements of immobile single fluorescent molecule images.

    PubMed

    DeSantis, Michael C; DeCenzo, Shawn H; Li, Je-Luen; Wang, Y M

    2010-03-29

    Standard deviation measurements of intensity profiles of stationary single fluorescent molecules are useful for studying axial localization, molecular orientation, and a fluorescence imaging system's spatial resolution. Here we report on the analysis of the precision of standard deviation measurements of intensity profiles of single fluorescent molecules imaged using an EMCCD camera.We have developed an analytical expression for the standard deviation measurement error of a single image which is a function of the total number of detected photons, the background photon noise, and the camera pixel size. The theoretical results agree well with the experimental, simulation, and numerical integration results. Using this expression, we show that single-molecule standard deviation measurements offer nanometer precision for a large range of experimental parameters.

  9. Assessing the stock market volatility for different sectors in Malaysia by using standard deviation and EWMA methods

    NASA Astrophysics Data System (ADS)

    Saad, Shakila; Ahmad, Noryati; Jaffar, Maheran Mohd

    2017-11-01

    Nowadays, the study on volatility concept especially in stock market has gained so much attention from a group of people engaged in financial and economic sectors. The applications of volatility concept in financial economics can be seen in valuation of option pricing, estimation of financial derivatives, hedging the investment risk and etc. There are various ways to measure the volatility value. However for this study, two methods are used; the simple standard deviation and Exponentially Weighted Moving Average (EWMA). The focus of this study is to measure the volatility on three different sectors of business in Malaysia, called primary, secondary and tertiary by using both methods. The daily and annual volatilities of different business sector based on stock prices for the period of 1 January 2014 to December 2014 have been calculated in this study. Result shows that different patterns of the closing stock prices and return give different volatility values when calculating using simple method and EWMA method.

  10. Estimating River Surface Elevation From ArcticDEM

    NASA Astrophysics Data System (ADS)

    Dai, Chunli; Durand, Michael; Howat, Ian M.; Altenau, Elizabeth H.; Pavelsky, Tamlin M.

    2018-04-01

    ArcticDEM is a collection of 2-m resolution, repeat digital surface models created from stereoscopic satellite imagery. To demonstrate the potential of ArcticDEM for measuring river stages and discharges, we estimate river surface heights along a reach of Tanana River near Fairbanks, Alaska, by the precise detection of river shorelines and mapping of shorelines to land surface elevation. The river height profiles over a 15-km reach agree with in situ measurements to a standard deviation less than 30 cm. The time series of ArcticDEM-derived river heights agree with the U.S. Geological Survey gage measurements with a standard deviation of 32 cm. Using the rating curve for that gage, we obtain discharges with a validation accuracy (root-mean-square error) of 234 m3/s (23% of the mean discharge). Our results demonstrate that ArcticDEM can accurately measure spatial and temporal variations of river surfaces, providing a new and powerful data set for hydrologic analysis.

  11. Quantification of intravoxel velocity standard deviation and turbulence intensity by generalizing phase-contrast MRI.

    PubMed

    Dyverfeldt, Petter; Sigfridsson, Andreas; Kvitting, John-Peder Escobar; Ebbers, Tino

    2006-10-01

    Turbulent flow, characterized by velocity fluctuations, is a contributing factor to the pathogenesis of several cardiovascular diseases. A clinical noninvasive tool for assessing turbulence is lacking, however. It is well known that the occurrence of multiple spin velocities within a voxel during the influence of a magnetic gradient moment causes signal loss in phase-contrast magnetic resonance imaging (PC-MRI). In this paper a mathematical derivation of an expression for computing the standard deviation (SD) of the blood flow velocity distribution within a voxel is presented. The SD is obtained from the magnitude of PC-MRI signals acquired with different first gradient moments. By exploiting the relation between the SD and turbulence intensity (TI), this method allows for quantitative studies of turbulence. For validation, the TI in an in vitro flow phantom was quantified, and the results compared favorably with previously published laser Doppler anemometry (LDA) results. This method has the potential to become an important tool for the noninvasive assessment of turbulence in the arterial tree.

  12. Global, Hemispheric, and Zonal Temperature Deviations Derived From a 63-Station Radiosonde Network

    DOE Data Explorer

    Angell, J. K. [NOAA, Air Resources Laboratory

    2011-01-01

    Surface temperatures and thickness-derived temperatures from a 63-station, globally distributed radiosonde network have been used to estimate global, hemispheric, and zonal annual and seasonal temperature deviations. Most of the temperature values used were column-mean temperatures, obtained from the differences in height (thickness) between constant-pressure surfaces at individual radiosonde stations. The pressure-height data before 1980 were obtained from published values in Monthly Climatic Data for the World. Between 1980 and 1990, Angell used data from both the Climatic Data for the World and the Global Telecommunications System (GTS) Network received at the National Meteorological Center. Between 1990 and 1995, the data were obtained only from GTS, and since 1995 the data have been obtained from National Center for Atmospheric Research files. The data are evaluated as deviations from the mean based on the interval 1958-1977. The station deviations have been averaged (with equal weighting) to obtain annual and seasonal temperature deviations for the globe, the Northern and Southern Hemispheres, and the following latitudinal zones: North (60° N-90° N) and South (60° S-90° S) Polar; North (30° N-60° N) and South (30° S-60° S) Temperate; North (10° N-30° N) and South (10° S-30° S) Subtropical; Tropical(30° S-30° N); and Equatorial (10° S-10° N). The seasonal calculations are for the standard meteorological seasons (i.e., winter is defined as December, January, and February; spring is March, April, and May, etc.) and the annual calculations are for December through the following November (i.e., for the four meteorological seasons). For greater details, see Angell and Korshover (1983) and Angell (1988, 1991)

  13. Special electronic distance meter calibration for precise engineering surveying industrial applications

    NASA Astrophysics Data System (ADS)

    Braun, Jaroslav; Štroner, Martin; Urban, Rudolf

    2015-05-01

    All surveying instruments and their measurements suffer from some errors. To refine the measurement results, it is necessary to use procedures restricting influence of the instrument errors on the measured values or to implement numerical corrections. In precise engineering surveying industrial applications the accuracy of the distances usually realized on relatively short distance is a key parameter limiting the resulting accuracy of the determined values (coordinates, etc.). To determine the size of systematic and random errors of the measured distances were made test with the idea of the suppression of the random error by the averaging of the repeating measurement, and reducing systematic errors influence of by identifying their absolute size on the absolute baseline realized in geodetic laboratory at the Faculty of Civil Engineering CTU in Prague. The 16 concrete pillars with forced centerings were set up and the absolute distances between the points were determined with a standard deviation of 0.02 millimetre using a Leica Absolute Tracker AT401. For any distance measured by the calibrated instruments (up to the length of the testing baseline, i.e. 38.6 m) can now be determined the size of error correction of the distance meter in two ways: Firstly by the interpolation on the raw data, or secondly using correction function derived by previous FFT transformation usage. The quality of this calibration and correction procedure was tested on three instruments (Trimble S6 HP, Topcon GPT-7501, Trimble M3) experimentally using Leica Absolute Tracker AT401. By the correction procedure was the standard deviation of the measured distances reduced significantly to less than 0.6 mm. In case of Topcon GPT-7501 is the nominal standard deviation 2 mm, achieved (without corrections) 2.8 mm and after corrections 0.55 mm; in case of Trimble M3 is nominal standard deviation 3 mm, achieved (without corrections) 1.1 mm and after corrections 0.58 mm; and finally in case of Trimble S6 is nominal standard deviation 1 mm, achieved (without corrections) 1.2 mm and after corrections 0.51 mm. Proposed procedure of the calibration and correction is in our opinion very suitable for increasing of the accuracy of the electronic distance measurement and allows the use of the common surveying instrument to achieve uncommonly high precision.

  14. Exploring Students' Conceptions of the Standard Deviation

    ERIC Educational Resources Information Center

    delMas, Robert; Liu, Yan

    2005-01-01

    This study investigated introductory statistics students' conceptual understanding of the standard deviation. A computer environment was designed to promote students' ability to coordinate characteristics of variation of values about the mean with the size of the standard deviation as a measure of that variation. Twelve students participated in an…

  15. 7 CFR 801.4 - Tolerances for dockage testers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ....10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Riddle separation ±0.10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Sieve separation ±0.10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Total...

  16. 7 CFR 801.4 - Tolerances for dockage testers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ....10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Riddle separation ±0.10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Sieve separation ±0.10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Total...

  17. 7 CFR 801.4 - Tolerances for dockage testers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ....10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Riddle separation ±0.10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Sieve separation ±0.10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Total...

  18. 7 CFR 801.4 - Tolerances for dockage testers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ....10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Riddle separation ±0.10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Sieve separation ±0.10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Total...

  19. Statistics as Unbiased Estimators: Exploring the Teaching of Standard Deviation

    ERIC Educational Resources Information Center

    Wasserman, Nicholas H.; Casey, Stephanie; Champion, Joe; Huey, Maryann

    2017-01-01

    This manuscript presents findings from a study about the knowledge for and planned teaching of standard deviation. We investigate how understanding variance as an unbiased (inferential) estimator--not just a descriptive statistic for the variation (spread) in data--is related to teachers' instruction regarding standard deviation, particularly…

  20. 7 CFR 801.4 - Tolerances for dockage testers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ....10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Riddle separation ±0.10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Sieve separation ±0.10 percent, mean deviation from standard dockage tester using Hard Red Winter wheat Total...

  1. 7 CFR 801.6 - Tolerances for moisture meters.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... moisture, mean deviation from National standard moisture meter using Hard Red Winter wheat Mid ±0.05 percent moisture, mean deviation from National standard moisture meter using Hard Red Winter wheat High ±0.05 percent moisture, mean deviation from National standard moisture meter using Hard Red Winter wheat...

  2. Optimal Mortgage Refinancing: A Closed Form Solution.

    PubMed

    Agarwal, Sumit; Driscoll, John C; Laibson, David I

    2013-06-01

    We derive the first closed-form optimal refinancing rule: Refinance when the current mortgage interest rate falls below the original rate by at least [Formula: see text] In this formula W (.) is the Lambert W -function, [Formula: see text] ρ is the real discount rate, λ is the expected real rate of exogenous mortgage repayment, σ is the standard deviation of the mortgage rate, κ/M is the ratio of the tax-adjusted refinancing cost and the remaining mortgage value, and τ is the marginal tax rate. This expression is derived by solving a tractable class of refinancing problems. Our quantitative results closely match those reported by researchers using numerical methods.

  3. Photometric Selection of a Massive Galaxy Catalog with z ≥ 0.55

    NASA Astrophysics Data System (ADS)

    Núñez, Carolina; Spergel, David N.; Ho, Shirley

    2017-02-01

    We present the development of a photometrically selected massive galaxy catalog, targeting Luminous Red Galaxies (LRGs) and massive blue galaxies at redshifts of z≥slant 0.55. Massive galaxy candidates are selected using infrared/optical color-color cuts, with optical data from the Sloan Digital Sky Survey (SDSS) and infrared data from “unWISE” forced photometry derived from the Wide-field Infrared Survey Explorer (WISE). The selection method is based on previously developed techniques to select LRGs with z> 0.5, and is optimized using receiver operating characteristic curves. The catalog contains 16,191,145 objects, selected over the full SDSS DR10 footprint. The redshift distribution of the resulting catalog is estimated using spectroscopic redshifts from the DEEP2 Galaxy Redshift Survey and photometric redshifts from COSMOS. Restframe U - B colors from DEEP2 are used to estimate LRG selection efficiency. Using DEEP2, the resulting catalog has an average redshift of z = 0.65, with a standard deviation of σ =2.0, and an average restframe of U-B=1.0, with a standard deviation of σ =0.27. Using COSMOS, the resulting catalog has an average redshift of z = 0.60, with a standard deviation of σ =1.8. We estimate 34 % of the catalog to be blue galaxies with z≥slant 0.55. An estimated 9.6 % of selected objects are blue sources with redshift z< 0.55. Stellar contamination is estimated to be 1.8%.

  4. Impact of bias-corrected reanalysis-derived lateral boundary conditions on WRF simulations

    NASA Astrophysics Data System (ADS)

    Moalafhi, Ditiro Benson; Sharma, Ashish; Evans, Jason Peter; Mehrotra, Rajeshwar; Rocheta, Eytan

    2017-08-01

    Lateral and lower boundary conditions derived from a suitable global reanalysis data set form the basis for deriving a dynamically consistent finer resolution downscaled product for climate and hydrological assessment studies. A problem with this, however, is that systematic biases have been noted to be present in the global reanalysis data sets that form these boundaries, biases which can be carried into the downscaled simulations thereby reducing their accuracy or efficacy. In this work, three Weather Research and Forecasting (WRF) model downscaling experiments are undertaken to investigate the impact of bias correcting European Centre for Medium range Weather Forecasting Reanalysis ERA-Interim (ERA-I) atmospheric temperature and relative humidity using Atmospheric Infrared Sounder (AIRS) satellite data. The downscaling is performed over a domain centered over southern Africa between the years 2003 and 2012. The sample mean and the mean as well as standard deviation at each grid cell for each variable are used for bias correction. The resultant WRF simulations of near-surface temperature and precipitation are evaluated seasonally and annually against global gridded observational data sets and compared with ERA-I reanalysis driving field. The study reveals inconsistencies between the impact of the bias correction prior to downscaling and the resultant model simulations after downscaling. Mean and standard deviation bias-corrected WRF simulations are, however, found to be marginally better than mean only bias-corrected WRF simulations and raw ERA-I reanalysis-driven WRF simulations. Performances, however, differ when assessing different attributes in the downscaled field. This raises questions about the efficacy of the correction procedures adopted.

  5. Standard electrode potential, Tafel equation, and the solvation thermodynamics.

    PubMed

    Matyushov, Dmitry V

    2009-06-21

    Equilibrium in the electronic subsystem across the solution-metal interface is considered to connect the standard electrode potential to the statistics of localized electronic states in solution. We argue that a correct derivation of the Nernst equation for the electrode potential requires a careful separation of the relevant time scales. An equation for the standard metal potential is derived linking it to the thermodynamics of solvation. The Anderson-Newns model for electronic delocalization between the solution and the electrode is combined with a bilinear model of solute-solvent coupling introducing nonlinear solvation into the theory of heterogeneous electron transfer. We therefore are capable of addressing the question of how nonlinear solvation affects electrochemical observables. The transfer coefficient of electrode kinetics is shown to be equal to the derivative of the free energy, or generalized force, required to shift the unoccupied electronic level in the bulk. The transfer coefficient thus directly quantifies the extent of nonlinear solvation of the redox couple. The current model allows the transfer coefficient to deviate from the value of 0.5 of the linear solvation models at zero electrode overpotential. The electrode current curves become asymmetric in respect to the change in the sign of the electrode overpotential.

  6. Radial gradient and radial deviation radiomic features from pre-surgical CT scans are associated with survival among lung adenocarcinoma patients

    PubMed Central

    Tunali, Ilke; Stringfield, Olya; Guvenis, Albert; Wang, Hua; Liu, Ying; Balagurunathan, Yoganand; Lambin, Philippe; Gillies, Robert J.; Schabath, Matthew B.

    2017-01-01

    The goal of this study was to extract features from radial deviation and radial gradient maps which were derived from thoracic CT scans of patients diagnosed with lung adenocarcinoma and assess whether these features are associated with overall survival. We used two independent cohorts from different institutions for training (n= 61) and test (n= 47) and focused our analyses on features that were non-redundant and highly reproducible. To reduce the number of features and covariates into a single parsimonious model, a backward elimination approach was applied. Out of 48 features that were extracted, 31 were eliminated because they were not reproducible or were redundant. We considered 17 features for statistical analysis and identified a final model containing the two most highly informative features that were associated with lung cancer survival. One of the two features, radial deviation outside-border separation standard deviation, was replicated in a test cohort exhibiting a statistically significant association with lung cancer survival (multivariable hazard ratio = 0.40; 95% confidence interval 0.17-0.97). Additionally, we explored the biological underpinnings of these features and found radial gradient and radial deviation image features were significantly associated with semantic radiological features. PMID:29221183

  7. Visualizing the Sample Standard Deviation

    ERIC Educational Resources Information Center

    Sarkar, Jyotirmoy; Rashid, Mamunur

    2017-01-01

    The standard deviation (SD) of a random sample is defined as the square-root of the sample variance, which is the "mean" squared deviation of the sample observations from the sample mean. Here, we interpret the sample SD as the square-root of twice the mean square of all pairwise half deviations between any two sample observations. This…

  8. Retrieval of land surface temperature (LST) from landsat TM6 and TIRS data by single channel radiative transfer algorithm using satellite and ground-based inputs

    NASA Astrophysics Data System (ADS)

    Chatterjee, R. S.; Singh, Narendra; Thapa, Shailaja; Sharma, Dravneeta; Kumar, Dheeraj

    2017-06-01

    The present study proposes land surface temperature (LST) retrieval from satellite-based thermal IR data by single channel radiative transfer algorithm using atmospheric correction parameters derived from satellite-based and in-situ data and land surface emissivity (LSE) derived by a hybrid LSE model. For example, atmospheric transmittance (τ) was derived from Terra MODIS spectral radiance in atmospheric window and absorption bands, whereas the atmospheric path radiance and sky radiance were estimated using satellite- and ground-based in-situ solar radiation, geographic location and observation conditions. The hybrid LSE model which is coupled with ground-based emissivity measurements is more versatile than the previous LSE models and yields improved emissivity values by knowledge-based approach. It uses NDVI-based and NDVI Threshold method (NDVITHM) based algorithms and field-measured emissivity values. The model is applicable for dense vegetation cover, mixed vegetation cover, bare earth including coal mining related land surface classes. The study was conducted in a coalfield of India badly affected by coal fire for decades. In a coal fire affected coalfield, LST would provide precise temperature difference between thermally anomalous coal fire pixels and background pixels to facilitate coal fire detection and monitoring. The derived LST products of the present study were compared with radiant temperature images across some of the prominent coal fire locations in the study area by graphical means and by some standard mathematical dispersion coefficients such as coefficient of variation, coefficient of quartile deviation, coefficient of quartile deviation for 3rd quartile vs. maximum temperature, coefficient of mean deviation (about median) indicating significant increase in the temperature difference among the pixels. The average temperature slope between adjacent pixels, which increases the potential of coal fire pixel detection from background pixels, is significantly larger in the derived LST products than the corresponding radiant temperature images.

  9. Long-term total ozone observations at Arosa (Switzerland) with Dobson and Brewer instruments (1988-2007)

    NASA Astrophysics Data System (ADS)

    Scarnato, B.; Staehelin, J.; Stübi, R.; Schill, H.

    2010-07-01

    Dobson and Brewer spectrophotometers are the standard instruments for ground-based total ozone monitoring under the World Meteorological Organization's Global Atmosphere Watch program. Both types of instruments have been simultaneously used at Arosa station (Switzerland) since 1988; presently two Dobson and three Brewer instruments (one of which is type Mark III) are in operation. The large data set of quasi-simultaneous measurements (defined here as observations performed less than 10 min apart) allows for the determination of both inter- and intrainstrumental precision. The results for one standard deviation of total ozone are ±0.5% for Dobson standard wavelength pair observations and ±0.15% for Brewer total ozone measurements. To transform Dobson data into Brewer total ozone observations, empirical transfer functions are used to describe the observed difference in seasonal variations of total ozone data derived from the two types of instruments (amounting to a seasonal amplitude of approximately 2% with maximum deviation in winter). The statistical model (applied to quasi-simultaneous measurements) includes the ozone effective temperature and the air mass multiplied by total ozone (ozone slant path) as explanatory variables; it removes the seasonal cycle in the difference and it allows the significance of the proxies introduced and systematic errors in the data to be determined. However, even when these transfer functions are applied, a 3% drift over about a 10 year period (1988-1997) between Arosa's Dobson and Brewer derived total ozone data series remains unexplained, adding to the model an aerosol proxy for which only part of the drift can be removed (related to the period 1992-1996).

  10. S193 radiometer brightness temperature precision/accuracy for SL2 and SL3

    NASA Technical Reports Server (NTRS)

    Pounds, D. J.; Krishen, K.

    1975-01-01

    The precision and accuracy with which the S193 radiometer measured the brightness temperature of ground scenes is investigated. Estimates were derived from data collected during Skylab missions. Homogeneous ground sites were selected and S193 radiometer brightness temperature data analyzed. The precision was expressed as the standard deviation of the radiometer acquired brightness temperature. Precision was determined to be 2.40 K or better depending on mode and target temperature.

  11. AMOS (ARPA Maui Optical Station) Seeing Quality Measurements

    DTIC Science & Technology

    1976-01-01

    for the microthermal probes. The report itself, while compiled and edited at RADC, may be considered as coming from equal contributions of...experiment 3 3. Power spectra for Run 16 for microthermal sensors 1, 4 and 5 13 4. Outer scale L0 versus time from start of mission for Runs 7, 13...Differential Angle of Arrival Standard Deviations and Derived Values of r 58 o LIST OF TABLES Page 1. Position of microthermal sensors for Augusc

  12. Attitudinal survey component of the study Quantity, quality, and support for research in the U.S. Fish and Wildlife Service: An organizational assessment: Report of methods and frequencies

    USGS Publications Warehouse

    Neilson, Jennifer R.; Lamb, Berton Lee; Swann, Earlene M.; Ratz, Joan; Ponds, Phadrea D.; Liverca, Joyce

    2005-01-01

    The findings presented in this report represent the basic results derived from the attitude assessment survey conducted in the last quarter of 2004. The findings set forth in this report are the frequency distributions for each question in the survey instrument for all respondents. The only statistics provided are descriptive in character - namely, means and associated standard deviations.

  13. Feasibility study and quality assessment of unmanned aircraft system-derived multispectral images

    NASA Astrophysics Data System (ADS)

    Chang, Kuo-Jen

    2017-04-01

    The purpose of study is to explore the precision and the applicability of UAS-derived multispectral images. In this study, the Micro-MCA6 multispectral camera was mounted on quadcopter. The Micro-MCA6 shoot images synchronized of each single band. By means of geotagged images and control points, the orthomosaic images of each single band generated firstly by 14cm resolution. The multispectral image was merged complete with 6 bands. In order to improve the spatial resolution, the 6 band image fused with 9cm resolution image taken from RGB camera. Quality evaluation of the image is verified of the each single band by using control points and check points. The standard deviations of errors are within 1 to 2 pixel resolution of each band. The quality of the multispectral image is compared with 3 cm resolution orthomosaic RGB image gathered from UAV in the same mission, as well. The standard deviations of errors are within 2 to 3 pixel resolution. The result shows that the errors resulting from the blurry and the band dislocation of the objects edge identification. To the end, the normalized difference vegetation index (NDVI) extracted from the image to explore the condition of vegetation and the nature of the environment. This study demonstrates the feasibility and the capability of the high resolution multispectral images.

  14. Species Identification of Fox-, Mink-, Dog-, and Rabbit-Derived Ingredients by Multiplex PCR and Real-Time PCR Assay.

    PubMed

    Wu, Qingqing; Xiang, Shengnan; Wang, Wenjun; Zhao, Jinyan; Xia, Jinhua; Zhen, Yueran; Liu, Bang

    2018-05-01

    Various detection methods have been developed to date for identification of animal species. New techniques based on PCR approach have raised the hope of developing better identification methods, which can overcome the limitations of the existing methods. PCR-based methods used the mitochondrial DNA (mtDNA) as well as nuclear DNA sequences. In this study, by targeting nuclear DNA, multiplex PCR and real-time PCR methods were developed to assist with qualitative and quantitative analysis. The multiplex PCR was found to simultaneously and effectively distinguish four species (fox, dog, mink, and rabbit) ingredients by the different sizes of electrophoretic bands: 480, 317, 220, and 209 bp. Real-time fluorescent PCR's amplification profiles and standard curves showed good quantitative measurement responses and linearity, as indicated by good repeatability and coefficient of determination R 2  > 0.99. The quantitative results of quaternary DNA mixtures including mink, fox, dog, and rabbit DNA are in line with our expectations: R.D. (relative deviation) varied between 1.98 and 12.23% and R.S.D. (relative standard deviation) varied between 3.06 and 11.51%, both of which are well within the acceptance criterion of ≤ 25%. Combining the two methods is suitable for the rapid identification and accurate quantification of fox-, dog-, mink-, and rabbit-derived ingredients in the animal products.

  15. Variation in the standard deviation of the lure rating distribution: Implications for estimates of recollection probability.

    PubMed

    Dopkins, Stephen; Varner, Kaitlin; Hoyer, Darin

    2017-10-01

    In word recognition semantic priming of test words increased the false-alarm rate and the mean of confidence ratings to lures. Such priming also increased the standard deviation of confidence ratings to lures and the slope of the z-ROC function, suggesting that the priming increased the standard deviation of the lure evidence distribution. The Unequal Variance Signal Detection (UVSD) model interpreted the priming as increasing the standard deviation of the lure evidence distribution. Without additional parameters the Dual Process Signal Detection (DPSD) model could only accommodate the results by fitting the data for related and unrelated primes separately, interpreting the priming, implausibly, as decreasing the probability of target recollection (DPSD). With an additional parameter, for the probability of false (lure) recollection the model could fit the data for related and unrelated primes together, interpreting the priming as increasing the probability of false recollection. These results suggest that DPSD estimates of target recollection probability will decrease with increases in the lure confidence/evidence standard deviation unless a parameter is included for false recollection. Unfortunately the size of a given lure confidence/evidence standard deviation relative to other possible lure confidence/evidence standard deviations is often unspecified by context. Hence the model often has no way of estimating false recollection probability and thereby correcting its estimates of target recollection probability.

  16. Down-Looking Interferometer Study II, Volume I,

    DTIC Science & Technology

    1980-03-01

    g(standard deviation of AN )(standard deviation of(3) where T’rm is the "reference spectrum", an estimate of the actual spectrum v gv T ’V Cgv . If jpj...spectrum T V . cgv . According to Eq. (2), Z is the standard deviation of the observed contrast spectral radiance AN divided by the effective rms system

  17. 40 CFR 61.207 - Radium-226 sampling and measurement procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... B, Method 114. (3) Calculate the mean, x 1, and the standard deviation, s 1, of the n 1 radium-226... owner or operator of a phosphogypsum stack shall report the mean, standard deviation, 95th percentile..., Method 114. (4) Recalculate the mean and standard deviation of the entire set of n 2 radium-226...

  18. Optical-frequency transfer over a single-span 1840 km fiber link.

    PubMed

    Droste, S; Ozimek, F; Udem, Th; Predehl, K; Hänsch, T W; Schnatz, H; Grosche, G; Holzwarth, R

    2013-09-13

    To compare the increasing number of optical frequency standards, highly stable optical signals have to be transferred over continental distances. We demonstrate optical-frequency transfer over a 1840-km underground optical fiber link using a single-span stabilization. The low inherent noise introduced by the fiber allows us to reach short term instabilities expressed as the modified Allan deviation of 2×10(-15) for a gate time τ of 1 s reaching 4×10(-19) in just 100 s. We find no systematic offset between the sent and transferred frequencies within the statistical uncertainty of about 3×10(-19). The spectral noise distribution of our fiber link at low Fourier frequencies leads to a τ(-2) slope in the modified Allan deviation, which is also derived theoretically.

  19. Flexner 2.0-Longitudinal Study of Student Participation in a Campus-Wide General Pathology Course for Graduate Students at The University of Arizona.

    PubMed

    Briehl, Margaret M; Nelson, Mark A; Krupinski, Elizabeth A; Erps, Kristine A; Holcomb, Michael J; Weinstein, John B; Weinstein, Ronald S

    2016-01-01

    Faculty members from the Department of Pathology at The University of Arizona College of Medicine-Tucson have offered a 4-credit course on enhanced general pathology for graduate students since 1996. The course is titled, "Mechanisms of Human Disease." Between 1997 and 2016, 270 graduate students completed Mechanisms of Human Disease. The students came from 21 programs of study. Analysis of Variance, using course grade as the dependent and degree, program, gender, and year (1997-2016) as independent variables, indicated that there was no significant difference in final grade (F = 0.112; P = .8856) as a function of degree (doctorate: mean = 89.60, standard deviation = 5.75; master's: mean = 89.34, standard deviation = 6.00; certificate program: mean = 88.64, standard deviation = 8.25), specific type of degree program (F = 2.066, P = .1316; life sciences: mean = 89.95, standard deviation = 6.40; pharmaceutical sciences: mean = 90.71, standard deviation = 4.57; physical sciences: mean = 87.79, standard deviation = 5.17), or as a function of gender (F = 2.96, P = .0865; males: mean = 88.09, standard deviation = 8.36; females: mean = 89.58, standard deviation = 5.82). Students in the physical and life sciences performed equally well. Mechanisms of Human Disease is a popular course that provides students enrolled in a variety of graduate programs with a medical school-based course on mechanisms of diseases. The addition of 2 new medically oriented Master of Science degree programs has nearly tripled enrollment. This graduate level course also potentially expands the interdisciplinary diversity of participants in our interprofessional education and collaborative practice exercises.

  20. Flexner 2.0—Longitudinal Study of Student Participation in a Campus-Wide General Pathology Course for Graduate Students at The University of Arizona

    PubMed Central

    Briehl, Margaret M.; Nelson, Mark A.; Krupinski, Elizabeth A.; Erps, Kristine A.; Holcomb, Michael J.; Weinstein, John B.

    2016-01-01

    Faculty members from the Department of Pathology at The University of Arizona College of Medicine-Tucson have offered a 4-credit course on enhanced general pathology for graduate students since 1996. The course is titled, “Mechanisms of Human Disease.” Between 1997 and 2016, 270 graduate students completed Mechanisms of Human Disease. The students came from 21 programs of study. Analysis of Variance, using course grade as the dependent and degree, program, gender, and year (1997-2016) as independent variables, indicated that there was no significant difference in final grade (F = 0.112; P = .8856) as a function of degree (doctorate: mean = 89.60, standard deviation = 5.75; master’s: mean = 89.34, standard deviation = 6.00; certificate program: mean = 88.64, standard deviation = 8.25), specific type of degree program (F = 2.066, P = .1316; life sciences: mean = 89.95, standard deviation = 6.40; pharmaceutical sciences: mean = 90.71, standard deviation = 4.57; physical sciences: mean = 87.79, standard deviation = 5.17), or as a function of gender (F = 2.96, P = .0865; males: mean = 88.09, standard deviation = 8.36; females: mean = 89.58, standard deviation = 5.82). Students in the physical and life sciences performed equally well. Mechanisms of Human Disease is a popular course that provides students enrolled in a variety of graduate programs with a medical school-based course on mechanisms of diseases. The addition of 2 new medically oriented Master of Science degree programs has nearly tripled enrollment. This graduate level course also potentially expands the interdisciplinary diversity of participants in our interprofessional education and collaborative practice exercises. PMID:28725783

  1. Combined search for the standard model Higgs boson decaying to bb using the D0 run II data set.

    PubMed

    Abazov, V M; Abbott, B; Acharya, B S; Adams, M; Adams, T; Alexeev, G D; Alkhazov, G; Alton, A; Alverson, G; Askew, A; Atkins, S; Augsten, K; Avila, C; Badaud, F; Bagby, L; Baldin, B; Bandurin, D V; Banerjee, S; Barberis, E; Baringer, P; Bartlett, J F; Bassler, U; Bazterra, V; Bean, A; Begalli, M; Bellantoni, L; Beri, S B; Bernardi, G; Bernhard, R; Bertram, I; Besançon, M; Beuselinck, R; Bhat, P C; Bhatia, S; Bhatnagar, V; Blazey, G; Blessing, S; Bloom, K; Boehnlein, A; Boline, D; Boos, E E; Borissov, G; Bose, T; Brandt, A; Brandt, O; Brock, R; Bross, A; Brown, D; Brown, J; Bu, X B; Buehler, M; Buescher, V; Bunichev, V; Burdin, S; Buszello, C P; Camacho-Pérez, E; Casey, B C K; Castilla-Valdez, H; Caughron, S; Chakrabarti, S; Chakraborty, D; Chan, K M; Chandra, A; Chapon, E; Chen, G; Chevalier-Théry, S; Cho, D K; Cho, S W; Choi, S; Choudhary, B; Cihangir, S; Claes, D; Clutter, J; Cooke, M; Cooper, W E; Corcoran, M; Couderc, F; Cousinou, M-C; Croc, A; Cutts, D; Das, A; Davies, G; de Jong, S J; De La Cruz-Burelo, E; Déliot, F; Demina, R; Denisov, D; Denisov, S P; Desai, S; Deterre, C; Devaughan, K; Diehl, H T; Diesburg, M; Ding, P F; Dominguez, A; Dubey, A; Dudko, L V; Duggan, D; Duperrin, A; Dutt, S; Dyshkant, A; Eads, M; Edmunds, D; Ellison, J; Elvira, V D; Enari, Y; Evans, H; Evdokimov, A; Evdokimov, V N; Facini, G; Feng, L; Ferbel, T; Fiedler, F; Filthaut, F; Fisher, W; Fisk, H E; Fortner, M; Fox, H; Fuess, S; Garcia-Bellido, A; García-González, J A; García-Guerra, G A; Gavrilov, V; Gay, P; Geng, W; Gerbaudo, D; Gerber, C E; Gershtein, Y; Ginther, G; Golovanov, G; Goussiou, A; Grannis, P D; Greder, S; Greenlee, H; Grenier, G; Gris, Ph; Grivaz, J-F; Grohsjean, A; Grünendahl, S; Grünewald, M W; Guillemin, T; Gutierrez, G; Gutierrez, P; Hagopian, S; Haley, J; Han, L; Harder, K; Harel, A; Hauptman, J M; Hays, J; Head, T; Hebbeker, T; Hedin, D; Hegab, H; Heinson, A P; Heintz, U; Hensel, C; Heredia De La Cruz, I; Herner, K; Hesketh, G; Hildreth, M D; Hirosky, R; Hoang, T; Hobbs, J D; Hoeneisen, B; Hogan, J; Hohlfeld, M; Howley, I; Hubacek, Z; Hynek, V; Iashvili, I; Ilchenko, Y; Illingworth, R; Ito, A S; Jabeen, S; Jaffré, M; Jayasinghe, A; Jeong, M S; Jesik, R; Jiang, P; Johns, K; Johnson, E; Johnson, M; Jonckheere, A; Jonsson, P; Joshi, J; Jung, A W; Juste, A; Kaadze, K; Kajfasz, E; Karmanov, D; Kasper, P A; Katsanos, I; Kehoe, R; Kermiche, S; Khalatyan, N; Khanov, A; Kharchilava, A; Kharzheev, Y N; Kiselevich, I; Kohli, J M; Kozelov, A V; Kraus, J; Kulikov, S; Kumar, A; Kupco, A; Kurča, T; Kuzmin, V A; Lammers, S; Landsberg, G; Lebrun, P; Lee, H S; Lee, S W; Lee, W M; Lei, X; Lellouch, J; Li, D; Li, H; Li, L; Li, Q Z; Lim, J K; Lincoln, D; Linnemann, J; Lipaev, V V; Lipton, R; Liu, H; Liu, Y; Lobodenko, A; Lokajicek, M; Lopes de Sa, R; Lubatti, H J; Luna-Garcia, R; Lyon, A L; Maciel, A K A; Madar, R; Magaña-Villalba, R; Malik, S; Malyshev, V L; Maravin, Y; Martínez-Ortega, J; McCarthy, R; McGivern, C L; Meijer, M M; Melnitchouk, A; Menezes, D; Mercadante, P G; Merkin, M; Meyer, A; Meyer, J; Miconi, F; Mondal, N K; Mulhearn, M; Nagy, E; Naimuddin, M; Narain, M; Nayyar, R; Neal, H A; Negret, J P; Neustroev, P; Nguyen, H T; Nunnemann, T; Orduna, J; Osman, N; Osta, J; Padilla, M; Pal, A; Parashar, N; Parihar, V; Park, S K; Partridge, R; Parua, N; Patwa, A; Penning, B; Perfilov, M; Peters, Y; Petridis, K; Petrillo, G; Pétroff, P; Pleier, M-A; Podesta-Lerma, P L M; Podstavkov, V M; Popov, A V; Prewitt, M; Price, D; Prokopenko, N; Qian, J; Quadt, A; Quinn, B; Rangel, M S; Ranjan, K; Ratoff, P N; Razumov, I; Renkel, P; Ripp-Baudot, I; Rizatdinova, F; Rominsky, M; Ross, A; Royon, C; Rubinov, P; Ruchti, R; Sajot, G; Salcido, P; Sánchez-Hernández, A; Sanders, M P; Santos, A S; Savage, G; Sawyer, L; Scanlon, T; Schamberger, R D; Scheglov, Y; Schellman, H; Schlobohm, S; Schwanenberger, C; Schwienhorst, R; Sekaric, J; Severini, H; Shabalina, E; Shary, V; Shaw, S; Shchukin, A A; Shivpuri, R K; Simak, V; Skubic, P; Slattery, P; Smirnov, D; Smith, K J; Snow, G R; Snow, J; Snyder, S; Söldner-Rembold, S; Sonnenschein, L; Soustruznik, K; Stark, J; Stoyanova, D A; Strauss, M; Suter, L; Svoisky, P; Takahashi, M; Titov, M; Tokmenin, V V; Tsai, Y-T; Tschann-Grimm, K; Tsybychev, D; Tuchming, B; Tully, C; Uvarov, L; Uvarov, S; Uzunyan, S; Van Kooten, R; van Leeuwen, W M; Varelas, N; Varnes, E W; Vasilyev, I A; Verdier, P; Verkheev, A Y; Vertogradov, L S; Verzocchi, M; Vesterinen, M; Vilanova, D; Vokac, P; Wahl, H D; Wang, M H L S; Wang, R-J; Warchol, J; Watts, G; Wayne, M; Weichert, J; Welty-Rieger, L; White, A; Wicke, D; Williams, M R J; Wilson, G W; Wobisch, M; Wood, D R; Wyatt, T R; Xie, Y; Yamada, R; Yang, S; Yang, W-C; Yasuda, T; Yatsunenko, Y A; Ye, W; Ye, Z; Yin, H; Yip, K; Youn, S W; Yu, J M; Zennamo, J; Zhao, T; Zhao, T G; Zhou, B; Zhu, J; Zielinski, M; Zieminska, D; Zivkovic, L

    2012-09-21

    We present the results of the combination of searches for the standard model Higgs boson produced in association with a W or Z boson and decaying into bb using the data sample collected with the D0 detector in pp collisions at √s = 1.96 TeV at the Fermilab Tevatron Collider. We derive 95% C.L. upper limits on the Higgs boson cross section relative to the standard model prediction in the mass range 100 GeV ≤ M(H) ≤ 150 GeV, and we exclude Higgs bosons with masses smaller than 102 GeV at the 95% C.L. In the mass range 120 GeV ≤ M(H) ≤145 GeV, the data exhibit an excess above the background prediction with a global significance of 1.5 standard deviations, consistent with the expectation in the presence of a standard model Higgs boson.

  2. Trace analysis of carbonyl compounds by liquid chromatography-mass spectrometry after collection as 2,4-dinitrophenylhydrazine derivatives.

    PubMed

    Sakuragawa, A; Yoneno, T; Inoue, K; Okutani, T

    1999-06-04

    This study describes the utilization of carbonyl- 2,4-dinitrophenylhydrazine (DNPH) derivatives for the determination of a micro amount of carbonyl compounds in air by liquid chromatography-mass spectrometry (LC-MS). After the carbonyl compounds are collected using a Waters Sep-Pak C18 cartridge column with-impregnated DNPH on octadecylsilica, they are eluted by acetonitrile as carbonyl-DNPH derivatives. A 20-mm3 aliquot of eluent is injected into the LC-MS system. The four derivatives (formaldehyde-, acetaldehyde-, acrolein- and acetone-DNPH) were eluted within 7 min with acetonitrile-water (60:40, v/v) as the mobile phase. The proposed method offers sub-ppb sensitivity and good reproducibility and was applied to the determination of these carbonyl compounds in actual air samples from store rooms, laboratories and offices. The relative standard deviations for these samples (n = 6) were 1 to 3%.

  3. Measuring (subglacial) bedform orientation, length, and longitudinal asymmetry - Method assessment.

    PubMed

    Jorge, Marco G; Brennand, Tracy A

    2017-01-01

    Geospatial analysis software provides a range of tools that can be used to measure landform morphometry. Often, a metric can be computed with different techniques that may give different results. This study is an assessment of 5 different methods for measuring longitudinal, or streamlined, subglacial bedform morphometry: orientation, length and longitudinal asymmetry, all of which require defining a longitudinal axis. The methods use the standard deviational ellipse (not previously applied in this context), the longest straight line fitting inside the bedform footprint (2 approaches), the minimum-size footprint-bounding rectangle, and Euler's approximation. We assess how well these methods replicate morphometric data derived from a manually mapped (visually interpreted) longitudinal axis, which, though subjective, is the most typically used reference. A dataset of 100 subglacial bedforms covering the size and shape range of those in the Puget Lowland, Washington, USA is used. For bedforms with elongation > 5, deviations from the reference values are negligible for all methods but Euler's approximation (length). For bedforms with elongation < 5, most methods had small mean absolute error (MAE) and median absolute deviation (MAD) for all morphometrics and thus can be confidently used to characterize the central tendencies of their distributions. However, some methods are better than others. The least precise methods are the ones based on the longest straight line and Euler's approximation; using these for statistical dispersion analysis is discouraged. Because the standard deviational ellipse method is relatively shape invariant and closely replicates the reference values, it is the recommended method. Speculatively, this study may also apply to negative-relief, and fluvial and aeolian bedforms.

  4. A Note on Standard Deviation and Standard Error

    ERIC Educational Resources Information Center

    Hassani, Hossein; Ghodsi, Mansoureh; Howell, Gareth

    2010-01-01

    Many students confuse the standard deviation and standard error of the mean and are unsure which, if either, to use in presenting data. In this article, we endeavour to address these questions and cover some related ambiguities about these quantities.

  5. Local fluctuations of ozone from 16 km to 45 km deduced from in situ vertical ozone profile

    NASA Technical Reports Server (NTRS)

    Moreau, G.; Robert, C.

    1994-01-01

    A vertical ozone profile obtained by an in situ ozone sonde from 16 km to 45 km, has allowed to observe local ozone concentration variations. These variations can be observed, thanks to a fast measurement system based on a UV absorption KrF excimer laser beam in a multipass cell. Ozone standard deviation versus altitude calculated from the mean is derived. Ozone variations or fluctuations are correlated with the different dynamic zones of the stratosphere.

  6. Low altitude wind shear statistics derived from measured and FAA proposed standard wind profiles

    NASA Technical Reports Server (NTRS)

    Dunham, R. E., Jr.; Usry, J. W.

    1984-01-01

    Wind shear statistics were calculated for a simulated data set using wind profiles proposed as a standard and compared to statistics derived from measured wind profile data. Wind shear values were grouped in altitude bands of 100 ft between 100 and 1400 ft, and in wind shear increments of 0.025 kt/ft between + or - 0.600 kt/ft for the simulated data set and between + or - 0.200 kt/ft for the measured set. No values existed outside the + or - 0.200 kt/ft boundaries for the measured data. Frequency distributions, means, and standard deviations were derived for each altitude band for both data sets, and compared. Also, frequency distributions were derived for the total sample for both data sets and compared. Frequency of occurrence of a given wind shear was about the same for both data sets for wind shears, but less than + or 0.10 kt/ft, but the simulated data set had larger values outside these boundaries. Neglecting the vertical wind component did not significantly affect the statistics for these data sets. The frequency of occurrence of wind shears for the flight measured data was essentially the same for each altitude band and the total sample, but the simulated data distributions were different for each altitude band. The larger wind shears for the flight measured data were found to have short durations.

  7. 14 CFR Appendix C to Part 91 - Operations in the North Atlantic (NAT) Minimum Navigation Performance Specifications (MNPS) Airspace

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... defined in section 1 of this appendix is as follows: (a) The standard deviation of lateral track errors shall be less than 6.3 NM (11.7 Km). Standard deviation is a statistical measure of data about a mean... standard deviation about the mean encompasses approximately 68 percent of the data and plus or minus 2...

  8. Determination of absorption changes from moments of distributions of times of flight of photons: optimization of measurement conditions for a two-layered tissue model.

    PubMed

    Liebert, Adam; Wabnitz, Heidrun; Elster, Clemens

    2012-05-01

    Time-resolved near-infrared spectroscopy allows for depth-selective determination of absorption changes in the adult human head that facilitates separation between cerebral and extra-cerebral responses to brain activation. The aim of the present work is to analyze which combinations of moments of measured distributions of times of flight (DTOF) of photons and source-detector separations are optimal for the reconstruction of absorption changes in a two-layered tissue model corresponding to extra- and intra-cerebral compartments. To this end we calculated the standard deviations of the derived absorption changes in both layers by considering photon noise and a linear relation between the absorption changes and the DTOF moments. The results show that the standard deviation of the absorption change in the deeper (superficial) layer increases (decreases) with the thickness of the superficial layer. It is confirmed that for the deeper layer the use of higher moments, in particular the variance of the DTOF, leads to an improvement. For example, when measurements at four different source-detector separations between 8 and 35 mm are available and a realistic thickness of the upper layer of 12 mm is assumed, the inclusion of the change in mean time of flight, in addition to the change in attenuation, leads to a reduction of the standard deviation of the absorption change in the deeper tissue layer by a factor of 2.5. A reduction by another 4% can be achieved by additionally including the change in variance.

  9. Planar structured perovskite solar cells by hybrid physical chemical vapor deposition with optimized perovskite film thickness

    NASA Astrophysics Data System (ADS)

    Wei, Xiangyang; Peng, Yanke; Jing, Gaoshan; Cui, Tianhong

    2018-05-01

    The thickness of perovskite absorber layer is a critical parameter to determine a planar structured perovskite solar cell’s performance. By modifying the spin coating speed and PbI2/N,N-dimethylformamide (DMF) solution concentration, the thickness of perovskite absorber layer was optimized to obtain high-performance solar cells. Using a PbI2/DMF solution of 1.3 mol/L, maximum power conversion efficiency (PCE) of a perovskite solar cell is 15.5% with a perovskite film of 413 nm at 5000 rpm, and PCE of 14.3% was also obtained for a solar cell with a perovskite film of 182 nm thick. It is derived that higher concentration of PbI2/DMF will result in better perovskite solar cells. Additionally, these perovskite solar cells are highly uniform. In 14 sets of solar cells, standard deviations of 11 sets of solar cells were less than 0.50% and the smallest standard deviation was 0.25%, which demonstrates the reliability and effectiveness of hybrid physical chemical vapor deposition (HPCVD) method.

  10. Effect of Random Circuit Fabrication Errors on Small Signal Gain and Phase in Helix Traveling Wave Tubes

    NASA Astrophysics Data System (ADS)

    Pengvanich, P.; Chernin, D. P.; Lau, Y. Y.; Luginsland, J. W.; Gilgenbach, R. M.

    2007-11-01

    Motivated by the current interest in mm-wave and THz sources, which use miniature, difficult-to-fabricate circuit components, we evaluate the statistical effects of random fabrication errors on a helix traveling wave tube amplifier's small signal characteristics. The small signal theory is treated in a continuum model in which the electron beam is assumed to be monoenergetic, and axially symmetric about the helix axis. Perturbations that vary randomly along the beam axis are introduced in the dimensionless Pierce parameters b, the beam-wave velocity mismatch, C, the gain parameter, and d, the cold tube circuit loss. Our study shows, as expected, that perturbation in b dominates the other two. The extensive numerical data have been confirmed by our analytic theory. They show in particular that the standard deviation of the output phase is linearly proportional to standard deviation of the individual perturbations in b, C, and d. Simple formulas have been derived which yield the output phase variations in terms of the statistical random manufacturing errors. This work was supported by AFOSR and by ONR.

  11. Longitudinal and Cross-Sectional Analyses of Visual Field Progression in Participants of the Ocular Hypertension Treatment Study (OHTS)

    PubMed Central

    Chauhan, Balwantray C; Keltner, John L; Cello, Kim E; Johnson, Chris A; Anderson, Douglas R; Gordon, Mae O; Kass, Michael A

    2014-01-01

    Purpose Visual field progression can be determined by evaluating the visual field by serial examinations (longitudinal analysis), or by a change in classification derived from comparison to age-matched normal data in single examinations (cross-sectional analysis). We determined the agreement between these two approaches in data from the Ocular Hypertension Treatment Study (OHTS). Methods Visual field data from 3088 eyes of 1570 OHTS participants (median follow-up 7 yrs, 15 tests with static automated perimetry) were analysed. Longitudinal analyses were performed with change probability with total and pattern deviation, and cross-sectional analysis with Glaucoma Hemifield Test, Corrected Pattern Standard Deviation, and Mean Deviation. The rates of Mean Deviation and General Height change were compared to estimate the degree of diffuse loss in emerging glaucoma. Results The agreement on progression in longitudinal and cross-sectional analyses ranged from 50% to 61% and remained nearly constant across a wide range of criteria. In contrast, the agreement on absence of progression ranged from 97% to 99.7%, being highest for the stricter criteria. Analyses of pattern deviation were more conservative than total deviation, with a 3 to 5 times lesser incidence of progression. Most participants developing field loss had both diffuse and focal change. Conclusions Despite considerable overall agreement, between 40 to 50% of eyes identified as having progressed with either longitudinal or cross-sectional analyses were identified with only one of the analyses. Because diffuse change is part of early glaucomatous damage, pattern deviation analyses may underestimate progression in patients with ocular hypertension. PMID:21149774

  12. Repeatable source, site, and path effects on the standard deviation for empirical ground-motion prediction models

    USGS Publications Warehouse

    Lin, P.-S.; Chiou, B.; Abrahamson, N.; Walling, M.; Lee, C.-T.; Cheng, C.-T.

    2011-01-01

    In this study, we quantify the reduction in the standard deviation for empirical ground-motion prediction models by removing ergodic assumption.We partition the modeling error (residual) into five components, three of which represent the repeatable source-location-specific, site-specific, and path-specific deviations from the population mean. A variance estimation procedure of these error components is developed for use with a set of recordings from earthquakes not heavily clustered in space.With most source locations and propagation paths sampled only once, we opt to exploit the spatial correlation of residuals to estimate the variances associated with the path-specific and the source-location-specific deviations. The estimation procedure is applied to ground-motion amplitudes from 64 shallow earthquakes in Taiwan recorded at 285 sites with at least 10 recordings per site. The estimated variance components are used to quantify the reduction in aleatory variability that can be used in hazard analysis for a single site and for a single path. For peak ground acceleration and spectral accelerations at periods of 0.1, 0.3, 0.5, 1.0, and 3.0 s, we find that the singlesite standard deviations are 9%-14% smaller than the total standard deviation, whereas the single-path standard deviations are 39%-47% smaller.

  13. Analysis of amino acids by HPLC/electrospray negative ion tandem mass spectrometry using 9-fluorenylmethoxycarbonyl chloride (Fmoc-Cl) derivatization.

    PubMed

    Ziegler, Jörg; Abel, Steffen

    2014-12-01

    A new method for the determination of amino acids is presented. It combines established methods for the derivatization of primary and secondary amino groups with 9-fluorenylmethoxycarbonyl chloride (Fmoc-Cl) with the subsequent amino acid specific detection of the derivatives by LC-ESI-MS/MS using multiple reaction monitoring (MRM). The derivatization proceeds within 5 min, and the resulting amino acid derivatives can be rapidly purified from matrix by solid-phase extraction (SPE) on HR-X resin and separated by reversed-phase HPLC. The Fmoc derivatives yield several amino acid specific fragment ions which opened the possibility to select amino acid specific MRM transitions. The method was applied to all 20 proteinogenic amino acids, and the quantification was performed using L-norvaline as standard. A limit of detection as low as 1 fmol/µl with a linear range of up to 125 pmol/µl could be obtained. Intraday and interday precisions were lower than 10 % relative standard deviations for most of the amino acids. Quantification using L-norvaline as internal standard gave very similar results compared to the quantification using deuterated amino acid as internal standards. Using this protocol, it was possible to record the amino acid profiles of only a single root from Arabidopsis thaliana seedlings and to compare it with the amino acid profiles of 20 dissected root meristems (200 μm).

  14. SU-E-J-67: Evaluation of Breathing Patterns for Respiratory-Gated Radiation Therapy Using Respiration Regularity Index

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cheong, K; Lee, M; Kang, S

    2014-06-01

    Purpose: Despite the importance of accurately estimating the respiration regularity of a patient in motion compensation treatment, an effective and simply applicable method has rarely been reported. The authors propose a simple respiration regularity index based on parameters derived from a correspondingly simplified respiration model. Methods: In order to simplify a patient's breathing pattern while preserving the data's intrinsic properties, we defined a respiration model as a power of cosine form with a baseline drift. According to this respiration formula, breathing-pattern fluctuation could be explained using four factors: sample standard deviation of respiration period, sample standard deviation of amplitude andmore » the results of simple regression of the baseline drift (slope and standard deviation of residuals of a respiration signal. Overall irregularity (δ) was defined as a Euclidean norm of newly derived variable using principal component analysis (PCA) for the four fluctuation parameters. Finally, the proposed respiration regularity index was defined as ρ=ln(1+(1/ δ))/2, a higher ρ indicating a more regular breathing pattern. Subsequently, we applied it to simulated and clinical respiration signals from real-time position management (RPM; Varian Medical Systems, Palo Alto, CA) and investigated respiration regularity. Moreover, correlations between the regularity of the first session and the remaining fractions were investigated using Pearson's correlation coefficient. Results: The respiration regularity was determined based on ρ; patients with ρ<0.3 showed worse regularity than the others, whereas ρ>0.7 was suitable for respiratory-gated radiation therapy (RGRT). Fluctuations in breathing cycle and amplitude were especially determinative of ρ. If the respiration regularity of a patient's first session was known, it could be estimated through subsequent sessions. Conclusions: Respiration regularity could be objectively determined using a respiration regularity index, ρ. Such single-index testing of respiration regularity can facilitate determination of RGRT availability in clinical settings, especially for free-breathing cases. This work was supported by a Korea Science and Engineering Foundation (KOSEF) grant funded by the Korean Ministry of Science, ICT and Future Planning (No. 2013043498)« less

  15. A better norm-referenced grading using the standard deviation criterion.

    PubMed

    Chan, Wing-shing

    2014-01-01

    The commonly used norm-referenced grading assigns grades to rank-ordered students in fixed percentiles. It has the disadvantage of ignoring the actual distance of scores among students. A simple norm-referenced grading via standard deviation is suggested for routine educational grading. The number of standard deviation of a student's score from the class mean was used as the common yardstick to measure achievement level. Cumulative probability of a normal distribution was referenced to help decide the amount of students included within a grade. RESULTS of the foremost 12 students from a medical examination were used for illustrating this grading method. Grading by standard deviation seemed to produce better cutoffs in allocating an appropriate grade to students more according to their differential achievements and had less chance in creating arbitrary cutoffs in between two similarly scored students than grading by fixed percentile. Grading by standard deviation has more advantages and is more flexible than grading by fixed percentile for norm-referenced grading.

  16. Personal Background Preparation Survey for early identification of nursing students at risk for attrition.

    PubMed

    Johnson, Craig W; Johnson, Ronald; Kim, Mira; McKee, John C

    2009-11-01

    During 2004 and 2005 orientations, all 187 and 188 new matriculates, respectively, in two southwestern U.S. nursing schools completed Personal Background and Preparation Surveys (PBPS) in the first predictive validity study of a diagnostic and prescriptive instrument for averting adverse academic status events (AASE) among nursing or health science professional students. One standard deviation increases in PBPS risks (p < 0.05) multiplied odds of first-year or second-year AASE by approximately 150%, controlling for school affiliation and underrepresented minority student (URMS) status. AASE odds one standard deviation above mean were 216% to 250% those one standard deviation below mean. Odds of first-year or second-year AASE for URMS one standard deviation above the 2004 PBPS mean were 587% those for non-URMS one standard deviation below mean. The PBPS consistently and significantly facilitated early identification of nursing students at risk for AASE, enabling proactive targeting of interventions for risk amelioration and AASE or attrition prevention. Copyright 2009, SLACK Incorporated.

  17. Demonstration of the Gore Module for Passive Ground Water Sampling

    DTIC Science & Technology

    2014-06-01

    ix ACRONYMS AND ABBREVIATIONS % RSD percent relative standard deviation 12DCA 1,2-dichloroethane 112TCA 1,1,2-trichloroethane 1122TetCA...Analysis of Variance ROD Record of Decision RSD relative standard deviation SBR Southern Bush River SVOC semi-volatile organic compound...replicate samples had a relative standard deviation ( RSD ) that was 20% or less. For the remaining analytes (PCE, cDCE, and chloroform), at least 70

  18. Impact of baseline systolic blood pressure on visit-to-visit blood pressure variability: the Kailuan study.

    PubMed

    Wang, Anxin; Li, Zhifang; Yang, Yuling; Chen, Guojuan; Wang, Chunxue; Wu, Yuntao; Ruan, Chunyu; Liu, Yan; Wang, Yilong; Wu, Shouling

    2016-01-01

    To investigate the relationship between baseline systolic blood pressure (SBP) and visit-to-visit blood pressure variability in a general population. This is a prospective longitudinal cohort study on cardiovascular risk factors and cardiovascular or cerebrovascular events. Study participants attended a face-to-face interview every 2 years. Blood pressure variability was defined using the standard deviation and coefficient of variation of all SBP values at baseline and follow-up visits. The coefficient of variation is the ratio of the standard deviation to the mean SBP. We used multivariate linear regression models to test the relationships between SBP and standard deviation, and between SBP and coefficient of variation. Approximately 43,360 participants (mean age: 48.2±11.5 years) were selected. In multivariate analysis, after adjustment for potential confounders, baseline SBPs <120 mmHg were inversely related to standard deviation (P<0.001) and coefficient of variation (P<0.001). In contrast, baseline SBPs ≥140 mmHg were significantly positively associated with standard deviation (P<0.001) and coefficient of variation (P<0.001). Baseline SBPs of 120-140 mmHg were associated with the lowest standard deviation and coefficient of variation. The associations between baseline SBP and standard deviation, and between SBP and coefficient of variation during follow-ups showed a U curve. Both lower and higher baseline SBPs were associated with increased blood pressure variability. To control blood pressure variability, a good target SBP range for a general population might be 120-139 mmHg.

  19. A QSPR model for prediction of diffusion coefficient of non-electrolyte organic compounds in air at ambient condition.

    PubMed

    Mirkhani, Seyyed Alireza; Gharagheizi, Farhad; Sattari, Mehdi

    2012-03-01

    Evaluation of diffusion coefficients of pure compounds in air is of great interest for many diverse industrial and air quality control applications. In this communication, a QSPR method is applied to predict the molecular diffusivity of chemical compounds in air at 298.15K and atmospheric pressure. Four thousand five hundred and seventy nine organic compounds from broad spectrum of chemical families have been investigated to propose a comprehensive and predictive model. The final model is derived by Genetic Function Approximation (GFA) and contains five descriptors. Using this dedicated model, we obtain satisfactory results quantified by the following statistical results: Squared Correlation Coefficient=0.9723, Standard Deviation Error=0.003 and Average Absolute Relative Deviation=0.3% for the predicted properties from existing experimental values. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. Ellipsoidal geometry in asteroid thermal models - The standard radiometric model

    NASA Technical Reports Server (NTRS)

    Brown, R. H.

    1985-01-01

    The major consequences of ellipsoidal geometry in an othewise standard radiometric model for asteroids are explored. It is shown that for small deviations from spherical shape a spherical model of the same projected area gives a reasonable aproximation to the thermal flux from an ellipsoidal body. It is suggested that large departures from spherical shape require that some correction be made for geometry. Systematic differences in the radii of asteroids derived radiometrically at 10 and 20 microns may result partly from nonspherical geometry. It is also suggested that extrapolations of the rotational variation of thermal flux from a nonspherical body based solely on the change in cross-sectional area are in error.

  1. A sequential quadratic programming algorithm using an incomplete solution of the subproblem

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Murray, W.; Prieto, F.J.

    1993-05-01

    We analyze sequential quadratic programming (SQP) methods to solve nonlinear constrained optimization problems that are more flexible in their definition than standard SQP methods. The type of flexibility introduced is motivated by the necessity to deviate from the standard approach when solving large problems. Specifically we no longer require a minimizer of the QP subproblem to be determined or particular Lagrange multiplier estimates to be used. Our main focus is on an SQP algorithm that uses a particular augmented Lagrangian merit function. New results are derived for this algorithm under weaker conditions than previously assumed; in particular, it is notmore » assumed that the iterates lie on a compact set.« less

  2. Flexner 3.0-Democratization of Medical Knowledge for the 21st Century: Teaching Medical Science Using K-12 General Pathology as a Gateway Course.

    PubMed

    Weinstein, Ronald S; Krupinski, Elizabeth A; Weinstein, John B; Graham, Anna R; Barker, Gail P; Erps, Kristine A; Holtrust, Angelette L; Holcomb, Michael J

    2016-01-01

    A medical school general pathology course has been reformatted into a K-12 general pathology course. This new course has been implemented at a series of 7 to 12 grade levels and the student outcomes compared. Typically, topics covered mirrored those in a medical school general pathology course serving as an introduction to the mechanisms of diseases. Assessment of student performance was based on their score on a multiple-choice final examination modeled after an examination given to medical students. Two Tucson area schools, in a charter school network, participated in the study. Statistical analysis of examination performances showed that there were no significant differences as a function of school ( F = 0.258, P = .6128), with students at school A having an average test scores of 87.03 (standard deviation = 8.99) and school B 86.00 (standard deviation = 8.18; F = 0.258, P = .6128). Analysis of variance was also conducted on the test scores as a function of gender and class grade. There were no significant differences as a function of gender ( F = 0.608, P = .4382), with females having an average score of 87.18 (standard deviation = 7.24) and males 85.61 (standard deviation = 9.85). There were also no significant differences as a function of grade level ( F = 0.627, P = .6003), with 7th graders having an average of 85.10 (standard deviation = 8.90), 8th graders 86.00 (standard deviation = 9.95), 9th graders 89.67 (standard deviation = 5.52), and 12th graders 86.90 (standard deviation = 7.52). The results demonstrated that middle and upper school students performed equally well in K-12 general pathology. Student course evaluations showed that the course met the student's expectations. One class voted K-12 general pathology their "elective course-of-the-year."

  3. Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range.

    PubMed

    Wan, Xiang; Wang, Wenqian; Liu, Jiming; Tong, Tiejun

    2014-12-19

    In systematic reviews and meta-analysis, researchers often pool the results of the sample mean and standard deviation from a set of similar clinical trials. A number of the trials, however, reported the study using the median, the minimum and maximum values, and/or the first and third quartiles. Hence, in order to combine results, one may have to estimate the sample mean and standard deviation for such trials. In this paper, we propose to improve the existing literature in several directions. First, we show that the sample standard deviation estimation in Hozo et al.'s method (BMC Med Res Methodol 5:13, 2005) has some serious limitations and is always less satisfactory in practice. Inspired by this, we propose a new estimation method by incorporating the sample size. Second, we systematically study the sample mean and standard deviation estimation problem under several other interesting settings where the interquartile range is also available for the trials. We demonstrate the performance of the proposed methods through simulation studies for the three frequently encountered scenarios, respectively. For the first two scenarios, our method greatly improves existing methods and provides a nearly unbiased estimate of the true sample standard deviation for normal data and a slightly biased estimate for skewed data. For the third scenario, our method still performs very well for both normal data and skewed data. Furthermore, we compare the estimators of the sample mean and standard deviation under all three scenarios and present some suggestions on which scenario is preferred in real-world applications. In this paper, we discuss different approximation methods in the estimation of the sample mean and standard deviation and propose some new estimation methods to improve the existing literature. We conclude our work with a summary table (an Excel spread sheet including all formulas) that serves as a comprehensive guidance for performing meta-analysis in different situations.

  4. Flexner 3.0—Democratization of Medical Knowledge for the 21st Century

    PubMed Central

    Krupinski, Elizabeth A.; Weinstein, John B.; Graham, Anna R.; Barker, Gail P.; Erps, Kristine A.; Holtrust, Angelette L.; Holcomb, Michael J.

    2016-01-01

    A medical school general pathology course has been reformatted into a K-12 general pathology course. This new course has been implemented at a series of 7 to 12 grade levels and the student outcomes compared. Typically, topics covered mirrored those in a medical school general pathology course serving as an introduction to the mechanisms of diseases. Assessment of student performance was based on their score on a multiple-choice final examination modeled after an examination given to medical students. Two Tucson area schools, in a charter school network, participated in the study. Statistical analysis of examination performances showed that there were no significant differences as a function of school (F = 0.258, P = .6128), with students at school A having an average test scores of 87.03 (standard deviation = 8.99) and school B 86.00 (standard deviation = 8.18; F = 0.258, P = .6128). Analysis of variance was also conducted on the test scores as a function of gender and class grade. There were no significant differences as a function of gender (F = 0.608, P = .4382), with females having an average score of 87.18 (standard deviation = 7.24) and males 85.61 (standard deviation = 9.85). There were also no significant differences as a function of grade level (F = 0.627, P = .6003), with 7th graders having an average of 85.10 (standard deviation = 8.90), 8th graders 86.00 (standard deviation = 9.95), 9th graders 89.67 (standard deviation = 5.52), and 12th graders 86.90 (standard deviation = 7.52). The results demonstrated that middle and upper school students performed equally well in K-12 general pathology. Student course evaluations showed that the course met the student’s expectations. One class voted K-12 general pathology their “elective course-of-the-year.” PMID:28725762

  5. The provenance and chemical variation of sandstones associated with the Mid-continent Rift System, U.S.A.

    USGS Publications Warehouse

    Cullers, R.L.; Berendsen, P.

    1998-01-01

    Sandstones along the northern portion of the Precambrian Mid-continent Rift System (MRS) have been petrographically and chemically analyzed for major elements and a variety of trace elements, including the REE. After the initial extrusion of the abundant basalts along the MRS, dominantly volcaniclastic sandstones of the Oronto Group were deposited. These volcaniclastic sandstones are covered by quartzose and subarkosic sandstones of the Bayfield Group. Thus the sandstones of the Oronto Group were derived from previously extruded basalts, whereas, the sandstones of the Bayfield Group were derived from Precambrian granitic gneisses located on the rift flanks. The chemical variation of these sandstones closely reflects the changing detrital modes with time. The elemental composition of the sandstones confirms the source lithologies suggested by the mineralogy and clasts. The Oronto Group sandstones contain lower ratios of elements concentrated in silicic source rocks (La or Th) relative to elements concentrated in basic source rocks (Co, Cr, or Sc) than the Bayfield Group. Also, the average size of the negative Eu anomaly of the sandstones of the Oronto Group is significantly less (Eu/Eu* mean ?? standard deviation = 0.79 ?? 0.13) than that of the Bayfield Group (mean + standard deviation = 0.57 ?? 0.09), also suggesting a more basic source for the former than the latter. Mixing models of elemental ratios give added insight as to the evolution of the rift. These models suggest that the volcanistic sandstones of the lower portion of the Oronto Group are derived from about 80 to 90 percent basalt and 10 to 20 percent granitoids. The rest of the Oronto Group and the lower to middle portion of the Bayfield Group could have formed by mixing of about 30 to 60 percent basalt and 40 to 70 percent granitoids. The upper portion of the Bayfield Group is likely derived from 80 to 100 percent granitoids and zero to 20 percent basalt.

  6. GPS receiver CODE bias estimation: A comparison of two methods

    NASA Astrophysics Data System (ADS)

    McCaffrey, Anthony M.; Jayachandran, P. T.; Themens, D. R.; Langley, R. B.

    2017-04-01

    The Global Positioning System (GPS) is a valuable tool in the measurement and monitoring of ionospheric total electron content (TEC). To obtain accurate GPS-derived TEC, satellite and receiver hardware biases, known as differential code biases (DCBs), must be estimated and removed. The Center for Orbit Determination in Europe (CODE) provides monthly averages of receiver DCBs for a significant number of stations in the International Global Navigation Satellite Systems Service (IGS) network. A comparison of the monthly receiver DCBs provided by CODE with DCBs estimated using the minimization of standard deviations (MSD) method on both daily and monthly time intervals, is presented. Calibrated TEC obtained using CODE-derived DCBs, is accurate to within 0.74 TEC units (TECU) in differenced slant TEC (sTEC), while calibrated sTEC using MSD-derived DCBs results in an accuracy of 1.48 TECU.

  7. Estimation of the neural drive to the muscle from surface electromyograms

    NASA Astrophysics Data System (ADS)

    Hofmann, David

    Muscle force is highly correlated with the standard deviation of the surface electromyogram (sEMG) produced by the active muscle. Correctly estimating this quantity of non-stationary sEMG and understanding its relation to neural drive and muscle force is of paramount importance. The single constituents of the sEMG are called motor unit action potentials whose biphasic amplitude can interfere (named amplitude cancellation), potentially affecting the standard deviation (Keenan etal. 2005). However, when certain conditions are met the Campbell-Hardy theorem suggests that amplitude cancellation does not affect the standard deviation. By simulation of the sEMG, we verify the applicability of this theorem to myoelectric signals and investigate deviations from its conditions to obtain a more realistic setting. We find no difference in estimated standard deviation with and without interference, standing in stark contrast to previous results (Keenan etal. 2008, Farina etal. 2010). Furthermore, since the theorem provides us with the functional relationship between standard deviation and neural drive we conclude that complex methods based on high density electrode arrays and blind source separation might not bear substantial advantages for neural drive estimation (Farina and Holobar 2016). Funded by NIH Grant Number 1 R01 EB022872 and NSF Grant Number 1208126.

  8. Comparison of a novel fixation device with standard suturing methods for spinal cord stimulators.

    PubMed

    Bowman, Richard G; Caraway, David; Bentley, Ishmael

    2013-01-01

    Spinal cord stimulation is a well-established treatment for chronic neuropathic pain of the trunk or limbs. Currently, the standard method of fixation is to affix the leads of the neuromodulation device to soft tissue, fascia or ligament, through the use of manually tying general suture. A novel semiautomated device is proposed that may be advantageous to the current standard. Comparison testing in an excised caprine spine and simulated bench top model was performed. Three tests were performed: 1) perpendicular pull from fascia of caprine spine; 2) axial pull from fascia of caprine spine; and 3) axial pull from Mylar film. Six samples of each configuration were tested for each scenario. Standard 2-0 Ethibond was compared with a novel semiautomated device (Anulex fiXate). Upon completion of testing statistical analysis was performed for each scenario. For perpendicular pull in the caprine spine, the failure load for standard suture was 8.95 lbs with a standard deviation of 1.39 whereas for fiXate the load was 15.93 lbs with a standard deviation of 2.09. For axial pull in the caprine spine, the failure load for standard suture was 6.79 lbs with a standard deviation of 1.55 whereas for fiXate the load was 12.31 lbs with a standard deviation of 4.26. For axial pull in Mylar film, the failure load for standard suture was 10.87 lbs with a standard deviation of 1.56 whereas for fiXate the load was 19.54 lbs with a standard deviation of 2.24. These data suggest a novel semiautomated device offers a method of fixation that may be utilized in lieu of standard suturing methods as a means of securing neuromodulation devices. Data suggest the novel semiautomated device in fact may provide a more secure fixation than standard suturing methods. © 2012 International Neuromodulation Society.

  9. Large deviation function for a driven underdamped particle in a periodic potential

    NASA Astrophysics Data System (ADS)

    Fischer, Lukas P.; Pietzonka, Patrick; Seifert, Udo

    2018-02-01

    Employing large deviation theory, we explore current fluctuations of underdamped Brownian motion for the paradigmatic example of a single particle in a one-dimensional periodic potential. Two different approaches to the large deviation function of the particle current are presented. First, we derive an explicit expression for the large deviation functional of the empirical phase space density, which replaces the level 2.5 functional used for overdamped dynamics. Using this approach, we obtain several bounds on the large deviation function of the particle current. We compare these to bounds for overdamped dynamics that have recently been derived, motivated by the thermodynamic uncertainty relation. Second, we provide a method to calculate the large deviation function via the cumulant generating function. We use this method to assess the tightness of the bounds in a numerical case study for a cosine potential.

  10. Biodiversity mapping in a tropical West African forest with airborne hyperspectral data.

    PubMed

    Vaglio Laurin, Gaia; Cheung-Wai Chan, Jonathan; Chen, Qi; Lindsell, Jeremy A; Coomes, David A; Guerriero, Leila; Del Frate, Fabio; Miglietta, Franco; Valentini, Riccardo

    2014-01-01

    Tropical forests are major repositories of biodiversity, but are fast disappearing as land is converted to agriculture. Decision-makers need to know which of the remaining forests to prioritize for conservation, but the only spatial information on forest biodiversity has, until recently, come from a sparse network of ground-based plots. Here we explore whether airborne hyperspectral imagery can be used to predict the alpha diversity of upper canopy trees in a West African forest. The abundance of tree species were collected from 64 plots (each 1250 m(2) in size) within a Sierra Leonean national park, and Shannon-Wiener biodiversity indices were calculated. An airborne spectrometer measured reflectances of 186 bands in the visible and near-infrared spectral range at 1 m(2) resolution. The standard deviations of these reflectance values and their first-order derivatives were calculated for each plot from the c. 1250 pixels of hyperspectral information within them. Shannon-Wiener indices were then predicted from these plot-based reflectance statistics using a machine-learning algorithm (Random Forest). The regression model fitted the data well (pseudo-R(2) = 84.9%), and we show that standard deviations of green-band reflectances and infra-red region derivatives had the strongest explanatory powers. Our work shows that airborne hyperspectral sensing can be very effective at mapping canopy tree diversity, because its high spatial resolution allows within-plot heterogeneity in reflectance to be characterized, making it an effective tool for monitoring forest biodiversity over large geographic scales.

  11. Biodiversity Mapping in a Tropical West African Forest with Airborne Hyperspectral Data

    PubMed Central

    Vaglio Laurin, Gaia; Chan, Jonathan Cheung-Wai; Chen, Qi; Lindsell, Jeremy A.; Coomes, David A.; Guerriero, Leila; Frate, Fabio Del; Miglietta, Franco; Valentini, Riccardo

    2014-01-01

    Tropical forests are major repositories of biodiversity, but are fast disappearing as land is converted to agriculture. Decision-makers need to know which of the remaining forests to prioritize for conservation, but the only spatial information on forest biodiversity has, until recently, come from a sparse network of ground-based plots. Here we explore whether airborne hyperspectral imagery can be used to predict the alpha diversity of upper canopy trees in a West African forest. The abundance of tree species were collected from 64 plots (each 1250 m2 in size) within a Sierra Leonean national park, and Shannon-Wiener biodiversity indices were calculated. An airborne spectrometer measured reflectances of 186 bands in the visible and near-infrared spectral range at 1 m2 resolution. The standard deviations of these reflectance values and their first-order derivatives were calculated for each plot from the c. 1250 pixels of hyperspectral information within them. Shannon-Wiener indices were then predicted from these plot-based reflectance statistics using a machine-learning algorithm (Random Forest). The regression model fitted the data well (pseudo-R2 = 84.9%), and we show that standard deviations of green-band reflectances and infra-red region derivatives had the strongest explanatory powers. Our work shows that airborne hyperspectral sensing can be very effective at mapping canopy tree diversity, because its high spatial resolution allows within-plot heterogeneity in reflectance to be characterized, making it an effective tool for monitoring forest biodiversity over large geographic scales. PMID:24937407

  12. Computer Programs for the Semantic Differential: Further Modifications.

    ERIC Educational Resources Information Center

    Lawson, Edwin D.; And Others

    The original nine programs for semantic differential analysis have been condensed into three programs which have been further refined and augmented. They yield: (1) means, standard deviations, and standard errors for each subscale on each concept; (2) Evaluation, Potency, and Activity (EPA) means, standard deviations, and standard errors; (3)…

  13. The kilometer-sized Main Belt asteroid population revealed by Spitzer

    NASA Astrophysics Data System (ADS)

    Ryan, E. L.; Mizuno, D. R.; Shenoy, S. S.; Woodward, C. E.; Carey, S. J.; Noriega-Crespo, A.; Kraemer, K. E.; Price, S. D.

    2015-06-01

    Aims: Multi-epoch Spitzer Space Telescope 24 μm data is utilized from the MIPSGAL and Taurus Legacy surveys to detect asteroids based on their relative motion. Methods: Infrared detections are matched to known asteroids and average diameters and albedos are derived using the near Earth asteroid thermal model (NEATM) for 1865 asteroids ranging in size from 0.2 to 169 km. A small subsample of these objects was also detected by IRAS or MSX and the single wavelength albedo and diameter fits derived from these data are within the uncertainties of the IRAS and/or MSX derived albedos and diameters and available occultation diameters, which demonstrates the robustness of our technique. Results: The mean geometric albedo of the small Main Belt asteroids in this sample is pV = 0.134 with a sample standard deviation of 0.106. The albedo distribution of this sample is far more diverse than the IRAS or MSX samples. The cumulative size-frequency distribution of asteroids in the Main Belt at small diameters is directly derived and a 3σ deviation from the fitted size-frequency distribution slope is found near 8 km. Completeness limits of the optical and infrared surveys are discussed. Tables 1-3 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/578/A42

  14. Determining a one-tailed upper limit for future sample relative reproducibility standard deviations.

    PubMed

    McClure, Foster D; Lee, Jung K

    2006-01-01

    A formula was developed to determine a one-tailed 100p% upper limit for future sample percent relative reproducibility standard deviations (RSD(R),%= 100s(R)/y), where S(R) is the sample reproducibility standard deviation, which is the square root of a linear combination of the sample repeatability variance (s(r)2) plus the sample laboratory-to-laboratory variance (s(L)2), i.e., S(R) = s(L)2, and y is the sample mean. The future RSD(R),% is expected to arise from a population of potential RSD(R),% values whose true mean is zeta(R),% = 100sigmaR, where sigmaR and mu are the population reproducibility standard deviation and mean, respectively.

  15. Packing Fraction of a Two-dimensional Eden Model with Random-Sized Particles

    NASA Astrophysics Data System (ADS)

    Kobayashi, Naoki; Yamazaki, Hiroshi

    2018-01-01

    We have performed a numerical simulation of a two-dimensional Eden model with random-size particles. In the present model, the particle radii are generated from a Gaussian distribution with mean μ and standard deviation σ. First, we have examined the bulk packing fraction for the Eden cluster and investigated the effects of the standard deviation and the total number of particles NT. We show that the bulk packing fraction depends on the number of particles and the standard deviation. In particular, for the dependence on the standard deviation, we have determined the asymptotic value of the bulk packing fraction in the limit of the dimensionless standard deviation. This value is larger than the packing fraction obtained in a previous study of the Eden model with uniform-size particles. Secondly, we have investigated the packing fraction of the entire Eden cluster including the effect of the interface fluctuation. We find that the entire packing fraction depends on the number of particles while it is independent of the standard deviation, in contrast to the bulk packing fraction. In a similar way to the bulk packing fraction, we have obtained the asymptotic value of the entire packing fraction in the limit NT → ∞. The obtained value of the entire packing fraction is smaller than that of the bulk value. This fact suggests that the interface fluctuation of the Eden cluster influences the packing fraction.

  16. Complexities of follicle deviation during selection of a dominant follicle in Bos taurus heifers.

    PubMed

    Ginther, O J; Baldrighi, J M; Siddiqui, M A R; Araujo, E R

    2016-11-01

    Follicle deviation during a follicular wave is a continuation in growth rate of the dominant follicle (F1) and decreased growth rate of the largest subordinate follicle (F2). The reliability of using an F1 of 8.5 mm to represent the beginning of expected deviation for experimental purposes during waves 1 and 2 (n = 26 per wave) was studied daily in heifers. Each wave was subgrouped as follows: standard subgroup (F1 larger than F2 for 2 days preceding deviation and F2 > 7.0 mm on the day of deviation), undersized subgroup (F2 did not attain 7.0 mm by the day of deviation), and switched subgroup (F2 larger than F1 at least once on the 2 days before or on the day of deviation). For each wave, mean differences in diameter between F1 and F2 changed abruptly at expected deviation in the standard subgroup but began 1 day before expected deviation in the undersized and switched subgroups. Concentrations of FSH in the wave-stimulating FSH surge and an increase in LH centered on expected deviation did not differ among subgroups. Results for each wave indicated that (1) expected deviation (F1, 8.5 mm) was a reliable representation of actual deviation in the standard subgroup but not in the undersized and switched subgroups; (2) concentrations of the gonadotropins normalized to expected deviation were similar among the three subgroups, indicating that the day of deviation was related to diameter of F1 and not F2; and (3) defining an expected day of deviation for experimental use should consider both diameter of F1 and the characteristics of deviation. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Search for WZ resonances in the fully leptonic channel using pp collisions at √s=8 TeV with the ATLAS detector

    DOE PAGES

    Aad, G.; Abbott, B.; Abdallah, J.; ...

    2014-10-07

    A search for resonant WZ production in the ℓνℓ'ℓ' (ℓ,ℓ'=e,μ) decay channel using 20.3 fb -1 of √s = 8 TeV pp collision data collected by the ATLAS experiment at LHC is presented. No significant deviation from the Standard Model prediction is observed and upper limits on the production cross sections of WZ resonances from an extended gauge model W' and from a simplified model of heavy vector triplets are derived. As a result, a corresponding observed (expected) lower mass limit of 1.52 (1.49) TeV is derived for the W' at the 95% confidence level.

  18. 40 CFR 90.708 - Cumulative Sum (CumSum) procedure.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... is 5.0×σ, and is a function of the standard deviation, σ. σ=is the sample standard deviation and is... individual engine. FEL=Family Emission Limit (the standard if no FEL). F=.25×σ. (2) After each test pursuant...

  19. Acoustic Correlates of Compensatory Adjustments to the Glottic and Supraglottic Structures in Patients with Unilateral Vocal Fold Paralysis

    PubMed Central

    2015-01-01

    The goal of this study was to analyse perceptually and acoustically the voices of patients with Unilateral Vocal Fold Paralysis (UVFP) and compare them to the voices of normal subjects. These voices were analysed perceptually with the GRBAS scale and acoustically using the following parameters: mean fundamental frequency (F0), standard-deviation of F0, jitter (ppq5), shimmer (apq11), mean harmonics-to-noise ratio (HNR), mean first (F1) and second (F2) formants frequency, and standard-deviation of F1 and F2 frequencies. Statistically significant differences were found in all of the perceptual parameters. Also the jitter, shimmer, HNR, standard-deviation of F0, and standard-deviation of the frequency of F2 were statistically different between groups, for both genders. In the male data differences were also found in F1 and F2 frequencies values and in the standard-deviation of the frequency of F1. This study allowed the documentation of the alterations resulting from UVFP and addressed the exploration of parameters with limited information for this pathology. PMID:26557690

  20. Dynamics of the standard deviations of three wind velocity components from the data of acoustic sounding

    NASA Astrophysics Data System (ADS)

    Krasnenko, N. P.; Kapegesheva, O. F.; Shamanaeva, L. G.

    2017-11-01

    Spatiotemporal dynamics of the standard deviations of three wind velocity components measured with a mini-sodar in the atmospheric boundary layer is analyzed. During the day on September 16 and at night on September 12 values of the standard deviation changed for the x- and y-components from 0.5 to 4 m/s, and for the z-component from 0.2 to 1.2 m/s. An analysis of the vertical profiles of the standard deviations of three wind velocity components for a 6-day measurement period has shown that the increase of σx and σy with altitude is well described by a power law dependence with exponent changing from 0.22 to 1.3 depending on the time of day, and σz depends linearly on the altitude. The approximation constants have been found and their errors have been estimated. The established physical regularities and the approximation constants allow the spatiotemporal dynamics of the standard deviation of three wind velocity components in the atmospheric boundary layer to be described and can be recommended for application in ABL models.

  1. A proof for Rhiel's range estimator of the coefficient of variation for skewed distributions.

    PubMed

    Rhiel, G Steven

    2007-02-01

    In this research study is proof that the coefficient of variation (CV(high-low)) calculated from the highest and lowest values in a set of data is applicable to specific skewed distributions with varying means and standard deviations. Earlier Rhiel provided values for d(n), the standardized mean range, and a(n), an adjustment for bias in the range estimator of micro. These values are used in estimating the coefficient of variation from the range for skewed distributions. The d(n) and an values were specified for specific skewed distributions with a fixed mean and standard deviation. In this proof it is shown that the d(n) and an values are applicable for the specific skewed distributions when the mean and standard deviation can take on differing values. This will give the researcher confidence in using this statistic for skewed distributions regardless of the mean and standard deviation.

  2. Statistical considerations for grain-size analyses of tills

    USGS Publications Warehouse

    Jacobs, A.M.

    1971-01-01

    Relative percentages of sand, silt, and clay from samples of the same till unit are not identical because of different lithologies in the source areas, sorting in transport, random variation, and experimental error. Random variation and experimental error can be isolated from the other two as follows. For each particle-size class of each till unit, a standard population is determined by using a normally distributed, representative group of data. New measurements are compared with the standard population and, if they compare satisfactorily, the experimental error is not significant and random variation is within the expected range for the population. The outcome of the comparison depends on numerical criteria derived from a graphical method rather than on a more commonly used one-way analysis of variance with two treatments. If the number of samples and the standard deviation of the standard population are substituted in a t-test equation, a family of hyperbolas is generated, each of which corresponds to a specific number of subsamples taken from each new sample. The axes of the graphs of the hyperbolas are the standard deviation of new measurements (horizontal axis) and the difference between the means of the new measurements and the standard population (vertical axis). The area between the two branches of each hyperbola corresponds to a satisfactory comparison between the new measurements and the standard population. Measurements from a new sample can be tested by plotting their standard deviation vs. difference in means on axes containing a hyperbola corresponding to the specific number of subsamples used. If the point lies between the branches of the hyperbola, the measurements are considered reliable. But if the point lies outside this region, the measurements are repeated. Because the critical segment of the hyperbola is approximately a straight line parallel to the horizontal axis, the test is simplified to a comparison between the means of the standard population and the means of the subsample. The minimum number of subsamples required to prove significant variation between samples caused by different lithologies in the source areas and sorting in transport can be determined directly from the graphical method. The minimum number of subsamples required is the maximum number to be run for economy of effort. ?? 1971 Plenum Publishing Corporation.

  3. Rapid determination of pyridine derivatives by dispersive liquid-liquid microextraction coupled with gas chromatography/gas sensor based on nanostructured conducting polypyrrole.

    PubMed

    Pirsa, Sajad; Alizadeh, Naader

    2011-12-15

    Polypyrrole (PPy) gas sensor has been prepared by polymerization of pyrrole on surfaces of commercial polymer fibers in the presence of an oxidizing agent. The sensing behavior of PPy gas sensor was investigated in the presence of pyridine derivatives. The resistive responses of the PPy gas sensor to pyridine derivatives were in the order of quinoline>pyridine>4-methyl pyridine and 2-methyl pyridine. The PPy gas sensor was used as gas chromatography (GC) detector and exhibited linear responses to pyridine derivatives in the ranges 40-4,000 ng. Dispersive liquid-liquid microextraction (DLLME) combined with GC/PPy gas sensor has been developed for simultaneous determination of pyridine derivatives and quinoline. The purposed method was used for determination of pyridine derivatives from cigarette smoke. The GC runs were completed in 4 min. The reproducibility of this method is suitable and good standard deviations were obtained. RSD value is less than 10% for all analytes. Copyright © 2011 Elsevier B.V. All rights reserved.

  4. Uav-Based Photogrammetric Point Clouds and Hyperspectral Imaging for Mapping Biodiversity Indicators in Boreal Forests

    NASA Astrophysics Data System (ADS)

    Saarinen, N.; Vastaranta, M.; Näsi, R.; Rosnell, T.; Hakala, T.; Honkavaara, E.; Wulder, M. A.; Luoma, V.; Tommaselli, A. M. G.; Imai, N. N.; Ribeiro, E. A. W.; Guimarães, R. B.; Holopainen, M.; Hyyppä, J.

    2017-10-01

    Biodiversity is commonly referred to as species diversity but in forest ecosystems variability in structural and functional characteristics can also be treated as measures of biodiversity. Small unmanned aerial vehicles (UAVs) provide a means for characterizing forest ecosystem with high spatial resolution, permitting measuring physical characteristics of a forest ecosystem from a viewpoint of biodiversity. The objective of this study is to examine the applicability of photogrammetric point clouds and hyperspectral imaging acquired with a small UAV helicopter in mapping biodiversity indicators, such as structural complexity as well as the amount of deciduous and dead trees at plot level in southern boreal forests. Standard deviation of tree heights within a sample plot, used as a proxy for structural complexity, was the most accurately derived biodiversity indicator resulting in a mean error of 0.5 m, with a standard deviation of 0.9 m. The volume predictions for deciduous and dead trees were underestimated by 32.4 m3/ha and 1.7 m3/ha, respectively, with standard deviation of 50.2 m3/ha for deciduous and 3.2 m3/ha for dead trees. The spectral features describing brightness (i.e. higher reflectance values) were prevailing in feature selection but several wavelengths were represented. Thus, it can be concluded that structural complexity can be predicted reliably but at the same time can be expected to be underestimated with photogrammetric point clouds obtained with a small UAV. Additionally, plot-level volume of dead trees can be predicted with small mean error whereas identifying deciduous species was more challenging at plot level.

  5. Alterations in in vivo knee joint kinematics following a femoral nerve branch block of the vastus medialis: Implications for patellofemoral pain syndrome.

    PubMed

    Sheehan, Frances T; Borotikar, Bhushan S; Behnam, Abrahm J; Alter, Katharine E

    2012-07-01

    A potential source of patellofemoral pain, one of the most common problems of the knee, is believed to be altered patellofemoral kinematics due to a force imbalance around the knee. Although no definitive etiology for this imbalance has been found, a weak vastus medialis is considered a primary factor. Therefore, this study's purpose was to determine how the loss of vastus medialis obliquus force alters three-dimensional in vivo knee joint kinematics during a volitional extension task. Eighteen asymptomatic female subjects with no history of knee pain or pathology participated in this IRB approved study. Patellofemoral and tibiofemoral kinematics were derived from velocity data acquired using dynamic cine-phase contrast MRI. The same kinematics were then acquired immediately after administering a motor branch block to the vastus medialis obliquus using 3-5ml of 1% lidocaine. A repeated measures analysis of variance was used to test the null hypothesis that the post- and pre-injection kinematics were no different. The null hypothesis was rejected for patellofemoral lateral shift (P=0.003, max change=1.8mm, standard deviation=1.7mm), tibiofemoral lateral shift (P<0.001, max change=2.1mm, standard deviation=2.9mm), and tibiofemoral external rotation (P<0.001, max change=3.7°, standard deviation=4.4°). The loss of vastus medialis obliquus function produced kinematic changes that mirrored the axial plane kinematics seen in individuals with patellofemoral pain, but could not account for the full extent of these changes. Thus, vastus medialis weakness is likely a major factor in, but not the sole source of, altered patellofemoral kinematics in such individuals. Published by Elsevier Ltd.

  6. Minimizing the Standard Deviation of Spatially Averaged Surface Cross-Sectional Data from the Dual-Frequency Precipitation Radar

    NASA Technical Reports Server (NTRS)

    Meneghini, Robert; Kim, Hyokyung

    2016-01-01

    For an airborne or spaceborne radar, the precipitation-induced path attenuation can be estimated from the measurements of the normalized surface cross section, sigma 0, in the presence and absence of precipitation. In one implementation, the mean rain-free estimate and its variability are found from a lookup table (LUT) derived from previously measured data. For the dual-frequency precipitation radar aboard the global precipitation measurement satellite, the nominal table consists of the statistics of the rain-free 0 over a 0.5 deg x 0.5 deg latitude-longitude grid using a three-month set of input data. However, a problem with the LUT is an insufficient number of samples in many cells. An alternative table is constructed by a stepwise procedure that begins with the statistics over a 0.25 deg x 0.25 deg grid. If the number of samples at a cell is too few, the area is expanded, cell by cell, choosing at each step that cell that minimizes the variance of the data. The question arises, however, as to whether the selected region corresponds to the smallest variance. To address this question, a second type of variable-averaging grid is constructed using all possible spatial configurations and computing the variance of the data within each region. Comparisons of the standard deviations for the fixed and variable-averaged grids are given as a function of incidence angle and surface type using a three-month set of data. The advantage of variable spatial averaging is that the average standard deviation can be reduced relative to the fixed grid while satisfying the minimum sample requirement.

  7. Template CoMFA Generates Single 3D-QSAR Models that, for Twelve of Twelve Biological Targets, Predict All ChEMBL-Tabulated Affinities

    PubMed Central

    Cramer, Richard D.

    2015-01-01

    The possible applicability of the new template CoMFA methodology to the prediction of unknown biological affinities was explored. For twelve selected targets, all ChEMBL binding affinities were used as training and/or prediction sets, making these 3D-QSAR models the most structurally diverse and among the largest ever. For six of the targets, X-ray crystallographic structures provided the aligned templates required as input (BACE, cdk1, chk2, carbonic anhydrase-II, factor Xa, PTP1B). For all targets including the other six (hERG, cyp3A4 binding, endocrine receptor, COX2, D2, and GABAa), six modeling protocols applied to only three familiar ligands provided six alternate sets of aligned templates. The statistical qualities of the six or seven models thus resulting for each individual target were remarkably similar. Also, perhaps unexpectedly, the standard deviations of the errors of cross-validation predictions accompanying model derivations were indistinguishable from the standard deviations of the errors of truly prospective predictions. These standard deviations of prediction ranged from 0.70 to 1.14 log units and averaged 0.89 (8x in concentration units) over the twelve targets, representing an average reduction of almost 50% in uncertainty, compared to the null hypothesis of “predicting” an unknown affinity to be the average of known affinities. These errors of prediction are similar to those from Tanimoto coefficients of fragment occurrence frequencies, the predominant approach to side effect prediction, which template CoMFA can augment by identifying additional active structural classes, by improving Tanimoto-only predictions, by yielding quantitative predictions of potency, and by providing interpretable guidance for avoiding or enhancing any specific target response. PMID:26065424

  8. Evaluation of Single-Doppler Radar Wind Retrievals in Flat and Complex Terrain

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Newsom, Rob K.; Berg, Larry K.; Pekour, Mikhail S.

    2014-08-01

    The accuracy of winds derived from NEXRAD level II data is assessed by comparison with independent observations from 915 MHz radar wind profilers. The evaluation is carried out at two locations with very different terrain characteristics. One site is located in an area of complex terrain within the State Line Wind Energy Center in northeast Oregon. The other site is located in an area of flat terrain on the east-central Florida coast. The National Severe Storm Laboratory’s 2DVar algorithm is used to retrieve wind fields from the KPDT (Pendleton OR) and KMLB (Melbourne FL) NEXRAD radars. Comparisons between the 2DVarmore » retrievals and the radar profilers were conducted over a period of about 6 months and at multiple height levels at each of the profiler sites. Wind speed correlations at most observation height levels fell in the range from 0.7 to 0.8, indicating that the retrieved winds followed temporal fluctuations in the profiler-observed winds reasonably well. The retrieved winds, however, consistently exhibited slow biases in the range of1 to 2 ms-1. Wind speed difference distributions were broad with standard deviations in the range from 3 to 4 ms-1. Results from the Florida site showed little change in the wind speed correlations and difference standard deviations with altitude between about 300 and 1400 m AGL. Over this same height range, results from the Oregon site showed a monotonic increase in the wind speed correlation and a monotonic decrease in the wind speed difference standard deviation with increasing altitude. The poorest overall agreement occurred at the lowest observable level (~300 m AGL) at the Oregon site, where the effects of the complex terrain were greatest.« less

  9. N2/O2/H2 Dual-Pump Cars: Validation Experiments

    NASA Technical Reports Server (NTRS)

    OByrne, S.; Danehy, P. M.; Cutler, A. D.

    2003-01-01

    The dual-pump coherent anti-Stokes Raman spectroscopy (CARS) method is used to measure temperature and the relative species densities of N2, O2 and H2 in two experiments. Average values and root-mean-square (RMS) deviations are determined. Mean temperature measurements in a furnace containing air between 300 and 1800 K agreed with thermocouple measurements within 26 K on average, while mean mole fractions agree to within 1.6 % of the expected value. The temperature measurement standard deviation averaged 64 K while the standard deviation of the species mole fractions averaged 7.8% for O2 and 3.8% for N2, based on 200 single-shot measurements. Preliminary measurements have also been performed in a flat-flame burner for fuel-lean and fuel-rich flames. Temperature standard deviations of 77 K were measured, and the ratios of H2 to N2 and O2 to N2 respectively had standard deviations from the mean value of 12.3% and 10% of the measured ratio.

  10. Period variability of coupled noisy oscillators

    NASA Astrophysics Data System (ADS)

    Mori, Fumito; Kori, Hiroshi

    2013-03-01

    Period variability, quantified by the standard deviation (SD) of the cycle-to-cycle period, is investigated for noisy phase oscillators. We define the checkpoint phase as the beginning or end point of one oscillation cycle and derive an expression for the SD as a function of this phase. We find that the SD is dependent on the checkpoint phase only when oscillators are coupled. The applicability of our theory is verified using a realistic model. Our work clarifies the relationship between period variability and synchronization from which valuable information regarding coupling can be inferred.

  11. Angular radiation models for earth-atmosphere system. Volume 2: Longwave radiation

    NASA Technical Reports Server (NTRS)

    Suttles, J. T.; Green, R. N.; Smith, G. L.; Wielicki, B. A.; Walker, I. J.; Taylor, V. R.; Stowe, L. L.

    1989-01-01

    The longwave angular radiation models that are required for analysis of satellite measurements of Earth radiation, such as those from the Earth Radiation Budget Experiment (ERBE) are presented. The models contain limb-darkening characteristics and mean fluxes. Limb-darkening characteristics are the longwave anisotropic factor and the standard deviation of the longwave radiance. Derivation of these models from the Nimbus 7 ERB (Earth Radiation Budget) data set is described. Tabulated values and computer-generated plots are included for the limb-darkening and mean-flux models.

  12. How Much Does Inbreeding Reduce Heterozygosity? Empirical Results from Aedes aegypti

    PubMed Central

    Powell, Jeffrey R.; Evans, Benjamin R.

    2017-01-01

    Deriving strains of mosquitoes with reduced genetic variation is useful, if not necessary, for many genetic studies. Inbreeding is the standard way of achieving this. Full-sib inbreeding the mosquito Aedes aegypti for seven generations reduced heterozygosity to 72% of the initial heterozygosity in contrast to the expected 13%. This deviation from expectations is likely due to high frequencies of deleterious recessive alleles that, given the number of markers studied (27,674 single nucleotide polymorphisms [SNPs]), must be quite densely spread in the genome. PMID:27799643

  13. Comparison of data inversion techniques for remotely sensed wide-angle observations of Earth emitted radiation

    NASA Technical Reports Server (NTRS)

    Green, R. N.

    1981-01-01

    The shape factor, parameter estimation, and deconvolution data analysis techniques were applied to the same set of Earth emitted radiation measurements to determine the effects of different techniques on the estimated radiation field. All three techniques are defined and their assumptions, advantages, and disadvantages are discussed. Their results are compared globally, zonally, regionally, and on a spatial spectrum basis. The standard deviations of the regional differences in the derived radiant exitance varied from 7.4 W-m/2 to 13.5 W-m/2.

  14. Effects of instrument characteristics on cloud properties retrieved from satellite imagery data

    NASA Technical Reports Server (NTRS)

    Baldwin, D. G.; Coakley, J. A., Jr.; Zhang, M. S.

    1986-01-01

    The relationships between sensor resolution and derived cloud properties in satellite remote sensing were studied by comparisons of cloud characteristics determined by spatial coherence analysis of AVHRR and GOES data. The latter data were simulated from 11 microns AVHRR data and were assigned a resolution (8 sq km) half that of the AVHRR. Day and nighttime passes were considered for single-layer maritime cloud systems. Sample radiance vs local standard deviation plots of 1024 points are provided for the same area from AVHRR and GOES-East sensors, demonstrating a qualitative agreement.

  15. Large Fluctuations for Spatial Diffusion of Cold Atoms

    NASA Astrophysics Data System (ADS)

    Aghion, Erez; Kessler, David A.; Barkai, Eli

    2017-06-01

    We use a new approach to study the large fluctuations of a heavy-tailed system, where the standard large-deviations principle does not apply. Large-deviations theory deals with tails of probability distributions and the rare events of random processes, for example, spreading packets of particles. Mathematically, it concerns the exponential falloff of the density of thin-tailed systems. Here we investigate the spatial density Pt(x ) of laser-cooled atoms, where at intermediate length scales the shape is fat tailed. We focus on the rare events beyond this range, which dominate important statistical properties of the system. Through a novel friction mechanism induced by the laser fields, the density is explored with the recently proposed non-normalized infinite-covariant density approach. The small and large fluctuations give rise to a bifractal nature of the spreading packet. We derive general relations which extend our theory to a class of systems with multifractal moments.

  16. Comparative study of navigated versus freehand osteochondral graft transplantation of the knee.

    PubMed

    Koulalis, Dimitrios; Di Benedetto, Paolo; Citak, Mustafa; O'Loughlin, Padhraig; Pearle, Andrew D; Kendoff, Daniel O

    2009-04-01

    Osteochondral lesions are a common sports-related injury for which osteochondral grafting, including mosaicplasty, is an established treatment. Computer navigation has been gaining popularity in orthopaedic surgery to improve accuracy and precision. Navigation improves angle and depth matching during harvest and placement of osteochondral grafts compared with conventional freehand open technique. Controlled laboratory study. Three cadaveric knees were used. Reference markers were attached to the femur, tibia, and donor/recipient site guides. Fifteen osteochondral grafts were harvested and inserted into recipient sites with computer navigation, and 15 similar grafts were inserted freehand. The angles of graft removal and placement as well as surface congruity (graft depth) were calculated for each surgical group. The mean harvesting angle at the donor site using navigation was 4 degrees (standard deviation, 2.3 degrees ; range, 1 degrees -9 degrees ) versus 12 degrees (standard deviation, 5.5 degrees ; range, 5 degrees -24 degrees ) using freehand technique (P < .0001). The recipient plug removal angle using the navigated technique was 3.3 degrees (standard deviation, 2.1 degrees ; range, 0 degrees -9 degrees ) versus 10.7 degrees (standard deviation, 4.9 degrees ; range, 2 degrees -17 degrees ) in freehand (P < .0001). The mean navigated recipient plug placement angle was 3.6 degrees (standard deviation, 2.0 degrees ; range, 1 degrees -9 degrees ) versus 10.6 degrees (standard deviation, 4.4 degrees ; range, 3 degrees -17 degrees ) with freehand technique (P = .0001). The mean height of plug protrusion under navigation was 0.3 mm (standard deviation, 0.2 mm; range, 0-0.6 mm) versus 0.5 mm (standard deviation, 0.3 mm; range, 0.2-1.1 mm) using a freehand technique (P = .0034). Significantly greater accuracy and precision were observed in harvesting and placement of the osteochondral grafts in the navigated procedures. Clinical studies are needed to establish a benefit in vivo. Improvement in the osteochondral harvest and placement is desirable to optimize clinical outcomes. Navigation shows great potential to improve both harvest and placement precision and accuracy, thus optimizing ultimate surface congruity.

  17. Lacosamide derivatives with anticonvulsant activity as carbonic anhydrase inhibitors. Molecular modeling, docking and QSAR analysis.

    PubMed

    Garro Martinez, Juan C; Vega-Hissi, Esteban G; Andrada, Matías F; Duchowicz, Pablo R; Torrens, Francisco; Estrada, Mario R

    2014-01-01

    Lacosamide is an anticonvulsant drug which presents carbonic anhydrase inhibition. In this paper, we analyzed the apparent relationship between both activities performing a molecular modeling, docking and QSAR studies on 18 lacosamide derivatives with known anticonvulsant activity. Docking results suggested the zinc-binding site of carbonic anhydrase is a possible target of lacosamide and lacosamide derivatives making favorable Van der Waals interactions with Asn67, Gln92, Phe131 and Thr200. The mathematical models revealed a poor relationship between the anticonvulsant activity and molecular descriptors obtained from DFT and docking calculations. However, a QSAR model was developed using Dragon software descriptors. The statistic parameters of the model are: correlation coefficient, R=0.957 and standard deviation, S=0.162. Our results provide new valuable information regarding the relationship between both activities and contribute important insights into the essential molecular requirements for the anticonvulsant activity.

  18. Matrix Summaries Improve Research Reports: Secondary Analyses Using Published Literature

    ERIC Educational Resources Information Center

    Zientek, Linda Reichwein; Thompson, Bruce

    2009-01-01

    Correlation matrices and standard deviations are the building blocks of many of the commonly conducted analyses in published research, and AERA and APA reporting standards recommend their inclusion when reporting research results. The authors argue that the inclusion of correlation/covariance matrices, standard deviations, and means can enhance…

  19. 30 CFR 74.8 - Measurement, accuracy, and reliability requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... concentration, as defined by the relative standard deviation of the distribution of measurements. The relative standard deviation shall be less than 0.1275 without bias for both full-shift measurements of 8 hours or... Standards, Regulations, and Variances, 1100 Wilson Boulevard, Room 2350, Arlington, Virginia 22209-3939...

  20. Quantitative assessment of commercial filter 'aids' for red-green colour defectives.

    PubMed

    Moreland, Jack D; Westland, Steven; Cheung, Vien; Dain, Steven J

    2010-09-01

    The claims made for 43 commercial filter 'aids', that they improve the colour discrimination of red-green colour defectives, are assessed for protanomaly and deuteranomaly by changes in the colour spacing of traffic signals (European Standard EN 1836:2005) and of the Farnsworth D15 test. Spectral transmittances of the 'aids' are measured and tristimulus values with and without 'aids' are computed using cone fundamentals and the spectral power distributions of either the D15 chips illuminated by CIE Illuminant C or of traffic signals. Chromaticities (l,s) are presented in cone excitation diagrams for protanomaly and deuteranomaly in terms of the relative excitation of their long (L), medium (M) and short (S) wavelength-sensitive cones. After correcting for non-uniform colour spacing in these diagrams, standard deviations parallel to the l and s axes are computed and enhancement factors E(l) and E(s) are derived as the ratio of 'aided' to 'unaided' standard deviations. Values of E(l) for traffic signals with most 'aids' are <1 and many do not meet the European signal detection standard. A few 'aids' have expansive E(l) factors but with inadequate utility: the largest being 1.2 for traffic signals and 1.3 for the D15 colours. Analyses, replicated for 19 'aids' from one manufacturer using 658 Munsell colours inside the D15 locus, yield E(l) factors within 1% of those found for the 16 D15 colours. © 2010 The Authors, Ophthalmic and Physiological Optics © 2010 The College of Optometrists.

  1. Nitrogen isotopic analyses by isotope-ratio-monitoring gas chromatography/mass spectrometry

    NASA Technical Reports Server (NTRS)

    Merritt, D. A.; Hayes, J. M.

    1994-01-01

    Amino acids containing natural-abundance levels of 15N were derivatized and analyzed isotopically using a technique in which individual compounds are separated by gas chromatography, combusted on-line, and the product stream sent directly to an isotope-ratio mass spectrometer. For samples of N2 gas, standard deviations of ratio measurement were better than 0.1% (Units for delta are parts per thousand or per million (%).) for samples larger than 400 pmol and better than 0.5% for samples larger than 25 pmol (0.1% 15N is equivalent to 0.00004 atom % 15N). Results duplicated those of conventional, batchwise analyses to within 0.05%. For combustion of organic compounds yielding CO2/N2 ratios between 14 and 28, in particular for N-acetyl n-propyl derivatives of amino acids, delta values were within 0.25% of results obtained using conventional techniques and standard deviations were better than 0.35%. Pooled data for measurements of all amino acids produced an accuracy and precision of 0.04 and 0.23%, respectively, when 2 nmol of each amino acid was injected on column and 20% of the stream of combustion products was delivered to the mass spectrometer.

  2. Antarctic Surface Temperatures Using Satellite Infrared Data from 1979 Through 1995

    NASA Technical Reports Server (NTRS)

    Comiso, Josefino C.; Stock, Larry

    1997-01-01

    The large scale spatial and temporal variations of surface ice temperature over the Antarctic region are studied using infrared data derived from the Nimbus-7 Temperature Humidity Infrared Radiometer (THIR) from 1979 through 1985 and from the NOAA Advanced Very High Resolution Radiometer (AVHRR) from 1984 through 1995. Enhanced techniques suitable for the polar regions for cloud masking and atmospheric correction were used before converting radiances to surface temperatures. The observed spatial distribution of surface temperature is highly correlated with surface ice sheet topography and agrees well with ice station temperatures with 2K to 4K standard deviations. The average surface ice temperature over the entire continent fluctuates by about 30K from summer to winter while that over the Antarctic Plateau varies by about 45K. Interannual fluctuations of the coldest interannual variations in surface temperature are highest at the Antarctic Plateau and the ice shelves (e.g., Ross and Ronne) with a periodic cycle of about 5 years and standard deviations of about 11K and 9K, respectively. Despite large temporal variability, however, especially in some regions, a regression analysis that includes removal of the seasonal cycle shows no apparent trend in temperature during the period 1979 through 1995.

  3. The effects of auditory stimulation with music on heart rate variability in healthy women.

    PubMed

    Roque, Adriano L; Valenti, Vitor E; Guida, Heraldo L; Campos, Mônica F; Knap, André; Vanderlei, Luiz Carlos M; Ferreira, Lucas L; Ferreira, Celso; Abreu, Luiz Carlos de

    2013-07-01

    There are no data in the literature with regard to the acute effects of different styles of music on the geometric indices of heart rate variability. In this study, we evaluated the acute effects of relaxant baroque and excitatory heavy metal music on the geometric indices of heart rate variability in women. We conducted this study in 21 healthy women ranging in age from 18 to 35 years. We excluded persons with previous experience with musical instruments and persons who had an affinity for the song styles. We evaluated two groups: Group 1 (n = 21), who were exposed to relaxant classical baroque musical and excitatory heavy metal auditory stimulation; and Group 2 (n = 19), who were exposed to both styles of music and white noise auditory stimulation. Using earphones, the volunteers were exposed to baroque or heavy metal music for five minutes. After the first music exposure to baroque or heavy metal music, they remained at rest for five minutes; subsequently, they were re-exposed to the opposite music (70-80 dB). A different group of women were exposed to the same music styles plus white noise auditory stimulation (90 dB). The sequence of the songs was randomized for each individual. We analyzed the following indices: triangular index, triangular interpolation of RR intervals and Poincaré plot (standard deviation of instantaneous beat-by-beat variability, standard deviation of the long-term RR interval, standard deviation of instantaneous beat-by-beat variability and standard deviation of the long-term RR interval ratio), low frequency, high frequency, low frequency/high frequency ratio, standard deviation of all the normal RR intervals, root-mean square of differences between the adjacent normal RR intervals and the percentage of adjacent RR intervals with a difference of duration greater than 50 ms. Heart rate variability was recorded at rest for 10 minutes. The triangular index and the standard deviation of the long-term RR interval indices were reduced during exposure to both music styles in the first group and tended to decrease in the second group whereas the white noise exposure decreased the high frequency index. We observed no changes regarding the triangular interpolation of RR intervals, standard deviation of instantaneous beat-by-beat variability and standard deviation of instantaneous beat-by-beat variability/standard deviation in the long-term RR interval ratio. We suggest that relaxant baroque and excitatory heavy metal music slightly decrease global heart rate variability because of the equivalent sound level.

  4. The effects of auditory stimulation with music on heart rate variability in healthy women

    PubMed Central

    Roque, Adriano L.; Valenti, Vitor E.; Guida, Heraldo L.; Campos, Mônica F.; Knap, André; Vanderlei, Luiz Carlos M.; Ferreira, Lucas L.; Ferreira, Celso; de Abreu, Luiz Carlos

    2013-01-01

    OBJECTIVES: There are no data in the literature with regard to the acute effects of different styles of music on the geometric indices of heart rate variability. In this study, we evaluated the acute effects of relaxant baroque and excitatory heavy metal music on the geometric indices of heart rate variability in women. METHODS: We conducted this study in 21 healthy women ranging in age from 18 to 35 years. We excluded persons with previous experience with musical instruments and persons who had an affinity for the song styles. We evaluated two groups: Group 1 (n = 21), who were exposed to relaxant classical baroque musical and excitatory heavy metal auditory stimulation; and Group 2 (n = 19), who were exposed to both styles of music and white noise auditory stimulation. Using earphones, the volunteers were exposed to baroque or heavy metal music for five minutes. After the first music exposure to baroque or heavy metal music, they remained at rest for five minutes; subsequently, they were re-exposed to the opposite music (70-80 dB). A different group of women were exposed to the same music styles plus white noise auditory stimulation (90 dB). The sequence of the songs was randomized for each individual. We analyzed the following indices: triangular index, triangular interpolation of RR intervals and Poincaré plot (standard deviation of instantaneous beat-by-beat variability, standard deviation of the long-term RR interval, standard deviation of instantaneous beat-by-beat variability and standard deviation of the long-term RR interval ratio), low frequency, high frequency, low frequency/high frequency ratio, standard deviation of all the normal RR intervals, root-mean square of differences between the adjacent normal RR intervals and the percentage of adjacent RR intervals with a difference of duration greater than 50 ms. Heart rate variability was recorded at rest for 10 minutes. RESULTS: The triangular index and the standard deviation of the long-term RR interval indices were reduced during exposure to both music styles in the first group and tended to decrease in the second group whereas the white noise exposure decreased the high frequency index. We observed no changes regarding the triangular interpolation of RR intervals, standard deviation of instantaneous beat-by-beat variability and standard deviation of instantaneous beat-by-beat variability/standard deviation in the long-term RR interval ratio. CONCLUSION: We suggest that relaxant baroque and excitatory heavy metal music slightly decrease global heart rate variability because of the equivalent sound level. PMID:23917660

  5. USL/DBMS NASA/PC R and D project C programming standards

    NASA Technical Reports Server (NTRS)

    Dominick, Wayne D. (Editor); Moreau, Dennis R.

    1984-01-01

    A set of programming standards intended to promote reliability, readability, and portability of C programs written for PC research and development projects is established. These standards must be adhered to except where reasons for deviation are clearly identified and approved by the PC team. Any approved deviation from these standards must also be clearly documented in the pertinent source code.

  6. Standard deviation index for stimulated Brillouin scattering suppression with different homogeneities.

    PubMed

    Ran, Yang; Su, Rongtao; Ma, Pengfei; Wang, Xiaolin; Zhou, Pu; Si, Lei

    2016-05-10

    We present a new quantitative index of standard deviation to measure the homogeneity of spectral lines in a fiber amplifier system so as to find the relation between the stimulated Brillouin scattering (SBS) threshold and the homogeneity of the corresponding spectral lines. A theoretical model is built and a simulation framework has been established to estimate the SBS threshold when input spectra with different homogeneities are set. In our experiment, by setting the phase modulation voltage to a constant value and the modulation frequency to different values, spectral lines with different homogeneities can be obtained. The experimental results show that the SBS threshold increases negatively with the standard deviation of the modulated spectrum, which is in good agreement with the theoretical results. When the phase modulation voltage is confined to 10 V and the modulation frequency is set to 80 MHz, the standard deviation of the modulated spectrum equals 0.0051, which is the lowest value in our experiment. Thus, at this time, the highest SBS threshold has been achieved. This standard deviation can be a good quantitative index in evaluating the power scaling potential in a fiber amplifier system, which is also a design guideline in suppressing the SBS to a better degree.

  7. Inferences from structural comparison: flexibility, secondary structure wobble and sequence alignment optimization.

    PubMed

    Zhang, Gaihua; Su, Zhen

    2012-01-01

    Work on protein structure prediction is very useful in biological research. To evaluate their accuracy, experimental protein structures or their derived data are used as the 'gold standard'. However, as proteins are dynamic molecular machines with structural flexibility such a standard may be unreliable. To investigate the influence of the structure flexibility, we analysed 3,652 protein structures of 137 unique sequences from 24 protein families. The results showed that (1) the three-dimensional (3D) protein structures were not rigid: the root-mean-square deviation (RMSD) of the backbone Cα of structures with identical sequences was relatively large, with the average of the maximum RMSD from each of the 137 sequences being 1.06 Å; (2) the derived data of the 3D structure was not constant, e.g. the highest ratio of the secondary structure wobble site was 60.69%, with the sequence alignments from structural comparisons of two proteins in the same family sometimes being completely different. Proteins may have several stable conformations and the data derived from resolved structures as a 'gold standard' should be optimized before being utilized as criteria to evaluate the prediction methods, e.g. sequence alignment from structural comparison. Helix/β-sheet transition exists in normal free proteins. The coil ratio of the 3D structure could affect its resolution as determined by X-ray crystallography.

  8. Flammability of gas mixtures. Part 1: fire potential.

    PubMed

    Schröder, Volkmar; Molnarne, Maria

    2005-05-20

    International and European dangerous substances and dangerous goods regulations refer to the standard ISO 10156 (1996). This standard includes a test method and a calculation procedure for the determination of the flammability of gases and gas mixtures in air. The substance indices for the calculation, the so called "Tci values", which characterise the fire potential, are provided as well. These ISO Tci values are derived from explosion diagrams of older literature sources which do not take into account the test method and the test apparatus. However, since the explosion limits are influenced by apparatus parameters, the Tci values and lower explosion limits, given by the ISO tables, are inconsistent with those measured according to the test method of the same standard. In consequence, applying the ISO Tci values can result in wrong classifications. In this paper internationally accepted explosion limit test methods were evaluated and Tci values were derived from explosion diagrams. Therefore, an "open vessel" method with flame propagation criterion was favoured. These values were compared with the Tci values listed in ISO 10156. In most cases, significant deviations were found. A detailed study about the influence of inert gases on flammability is the objective of Part 2.

  9. figure1.nc

    EPA Pesticide Factsheets

    NetCDF file of the SREF standard deviation of wind speed and direction that was used to inject variability in the FDDA input.variable U_NDG_OLD contains standard deviation of wind speed (m/s)variable V_NDG_OLD contains the standard deviation of wind direction (deg)This dataset is associated with the following publication:Gilliam , R., C. Hogrefe , J. Godowitch, S. Napelenok , R. Mathur , and S.T. Rao. Impact of inherent meteorology uncertainty on air quality model predictions. JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES. American Geophysical Union, Washington, DC, USA, 120(23): 12,259–12,280, (2015).

  10. Long-term variability in the date of monsoon onset over western India

    NASA Astrophysics Data System (ADS)

    Adamson, George C. D.; Nash, David J.

    2013-06-01

    The date of onset of the southwest monsoon in western India is critical for farmers as it influences the timing of crop plantation and the duration of the summer rainy season. Identifying long-term variability in the date of monsoon onset is difficult, however, as onset dates derived from the reanalysis of instrumental rainfall data are only available for the region from 1879. This study uses documentary evidence and newly uncovered instrumental data to reconstruct annual monsoon onset dates for western India for the period 1781-1878, extending the existing record by 97 years. The mean date of monsoon onset over the Mumbai (Bombay) area during the reconstruction period was 10 June with a standard deviation of 6.9 days. This is similar to the mean and standard deviation of the date of monsoon onset derived from instrumental data for the twentieth century. The earliest identified onset date was 23 May (in 1802 and 1839) and the latest 22 June (in 1825). The longer-term perspective provided by this study suggests that the climatic regime that governs monsoon advance over western India did not change substantially from 1781 to 1955. Monsoon onset over Mumbai has occurred at a generally later date since this time. Our results indicate that this change is unprecedented during the last 230 years. Following a discussion of the results, the nature of the relationship between the date of monsoon onset and the El Niño-Southern Oscillation is discussed. This relationship is shown to have been stable since 1781.

  11. Least-Squares Data Adjustment with Rank-Deficient Data Covariance Matrices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, J.G.

    2011-07-01

    A derivation of the linear least-squares adjustment formulae is required that avoids the assumption that the covariance matrix of prior parameters can be inverted. Possible proofs are of several kinds, including: (i) extension of standard results for the linear regression formulae, and (ii) minimization by differentiation of a quadratic form of the deviations in parameters and responses. In this paper, the least-squares adjustment equations are derived in both these ways, while explicitly assuming that the covariance matrix of prior parameters is singular. It will be proved that the solutions are unique and that, contrary to statements that have appeared inmore » the literature, the least-squares adjustment problem is not ill-posed. No modification is required to the adjustment formulae that have been used in the past in the case of a singular covariance matrix for the priors. In conclusion: The linear least-squares adjustment formula that has been used in the past is valid in the case of a singular covariance matrix for the covariance matrix of prior parameters. Furthermore, it provides a unique solution. Statements in the literature, to the effect that the problem is ill-posed are wrong. No regularization of the problem is required. This has been proved in the present paper by two methods, while explicitly assuming that the covariance matrix of prior parameters is singular: i) extension of standard results for the linear regression formulae, and (ii) minimization by differentiation of a quadratic form of the deviations in parameters and responses. No modification is needed to the adjustment formulae that have been used in the past. (author)« less

  12. 75 FR 67093 - Iceberg Water Deviating From Identity Standard; Temporary Permit for Market Testing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-P-0517] Iceberg Water Deviating From Identity Standard; Temporary Permit for Market Testing AGENCY: Food and Drug... from the requirements of the standards of identity issued under section 401 of the Federal Food, Drug...

  13. 78 FR 2273 - Canned Tuna Deviating From Identity Standard; Temporary Permit for Market Testing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-P-1189] Canned Tuna Deviating From Identity Standard; Temporary Permit for Market Testing AGENCY: Food and Drug... interstate shipment of experimental packs of food varying from the requirements of standards of identity...

  14. Upgraded FAA Airfield Capacity Model. Volume 2. Technical Description of Revisions

    DTIC Science & Technology

    1981-02-01

    the threshold t k a the time at which departure k is released FIGURE 3-1 TIME AXIS DIAGRAM OF SINGLE RUNWAY OPERATIONS 3-2 J"- SIGMAR the standard...standard deviation of the interarrival time. SIGMAR - the standard deviation of the arrival runway occupancy time. A-5 SINGLE - program subroutine for

  15. Methods of editing cloud and atmospheric layer affected pixels from satellite data

    NASA Technical Reports Server (NTRS)

    Nixon, P. R.; Wiegand, C. L.; Richardson, A. J.; Johnson, M. P. (Principal Investigator)

    1982-01-01

    Subvisible cirrus clouds (SCi) were easily distinguished in mid-infrared (MIR) TIROS-N daytime data from south Texas and northeast Mexico. The MIR (3.55-3.93 micrometer) pixel digital count means of the SCi affected areas were more than 3.5 standard deviations on the cold side of the scene means. (These standard deviations were made free of the effects of unusual instrument error by factoring out the Ch 3 MIR noise on the basis of detailed examination of noisy and noise-free pixels). SCi affected areas in the IR Ch 4 (10.5-11.5 micrometer) appeared cooler than the general scene, but were not as prominent as in Ch 3, being less than 2 standard deviations from the scene mean. Ch 3 and 4 standard deviations and coefficients of variation are not reliable indicators, by themselves, of the presence of SCi because land features can have similar statistical properties.

  16. Optimal Mortgage Refinancing: A Closed Form Solution

    PubMed Central

    Agarwal, Sumit; Driscoll, John C.; Laibson, David I.

    2013-01-01

    We derive the first closed-form optimal refinancing rule: Refinance when the current mortgage interest rate falls below the original rate by at least 1ψ[ϕ+W(−exp(−ϕ))]. In this formula W(.) is the Lambert W-function, ψ=2(ρ+λ)σ,ϕ=1+ψ(ρ+λ)κ∕M(1−τ), ρ is the real discount rate, λ is the expected real rate of exogenous mortgage repayment, σ is the standard deviation of the mortgage rate, κ/M is the ratio of the tax-adjusted refinancing cost and the remaining mortgage value, and τ is the marginal tax rate. This expression is derived by solving a tractable class of refinancing problems. Our quantitative results closely match those reported by researchers using numerical methods. PMID:25843977

  17. A Taxonomy of Delivery and Documentation Deviations During Delivery of High-Fidelity Simulations.

    PubMed

    McIvor, William R; Banerjee, Arna; Boulet, John R; Bekhuis, Tanja; Tseytlin, Eugene; Torsher, Laurence; DeMaria, Samuel; Rask, John P; Shotwell, Matthew S; Burden, Amanda; Cooper, Jeffrey B; Gaba, David M; Levine, Adam; Park, Christine; Sinz, Elizabeth; Steadman, Randolph H; Weinger, Matthew B

    2017-02-01

    We developed a taxonomy of simulation delivery and documentation deviations noted during a multicenter, high-fidelity simulation trial that was conducted to assess practicing physicians' performance. Eight simulation centers sought to implement standardized scenarios over 2 years. Rules, guidelines, and detailed scenario scripts were established to facilitate reproducible scenario delivery; however, pilot trials revealed deviations from those rubrics. A taxonomy with hierarchically arranged terms that define a lack of standardization of simulation scenario delivery was then created to aid educators and researchers in assessing and describing their ability to reproducibly conduct simulations. Thirty-six types of delivery or documentation deviations were identified from the scenario scripts and study rules. Using a Delphi technique and open card sorting, simulation experts formulated a taxonomy of high-fidelity simulation execution and documentation deviations. The taxonomy was iteratively refined and then tested by 2 investigators not involved with its development. The taxonomy has 2 main classes, simulation center deviation and participant deviation, which are further subdivided into as many as 6 subclasses. Inter-rater classification agreement using the taxonomy was 74% or greater for each of the 7 levels of its hierarchy. Cohen kappa calculations confirmed substantial agreement beyond that expected by chance. All deviations were classified within the taxonomy. This is a useful taxonomy that standardizes terms for simulation delivery and documentation deviations, facilitates quality assurance in scenario delivery, and enables quantification of the impact of deviations upon simulation-based performance assessment.

  18. The correlation between relatives on the supposition of genomic imprinting.

    PubMed Central

    Spencer, Hamish G

    2002-01-01

    Standard genetic analyses assume that reciprocal heterozygotes are, on average, phenotypically identical. If a locus is subject to genomic imprinting, however, this assumption does not hold. We incorporate imprinting into the standard quantitative-genetic model for two alleles at a single locus, deriving expressions for the additive and dominance components of genetic variance, as well as measures of resemblance among relatives. We show that, in contrast to the case with Mendelian expression, the additive and dominance deviations are correlated. In principle, this correlation allows imprinting to be detected solely on the basis of different measures of familial resemblances, but in practice, the standard error of the estimate is likely to be too large for a test to have much statistical power. The effects of genomic imprinting will need to be incorporated into quantitative-genetic models of many traits, for example, those concerned with mammalian birthweight. PMID:12019254

  19. The correlation between relatives on the supposition of genomic imprinting.

    PubMed

    Spencer, Hamish G

    2002-05-01

    Standard genetic analyses assume that reciprocal heterozygotes are, on average, phenotypically identical. If a locus is subject to genomic imprinting, however, this assumption does not hold. We incorporate imprinting into the standard quantitative-genetic model for two alleles at a single locus, deriving expressions for the additive and dominance components of genetic variance, as well as measures of resemblance among relatives. We show that, in contrast to the case with Mendelian expression, the additive and dominance deviations are correlated. In principle, this correlation allows imprinting to be detected solely on the basis of different measures of familial resemblances, but in practice, the standard error of the estimate is likely to be too large for a test to have much statistical power. The effects of genomic imprinting will need to be incorporated into quantitative-genetic models of many traits, for example, those concerned with mammalian birthweight.

  20. Feature selection for elderly faller classification based on wearable sensors.

    PubMed

    Howcroft, Jennifer; Kofman, Jonathan; Lemaire, Edward D

    2017-05-30

    Wearable sensors can be used to derive numerous gait pattern features for elderly fall risk and faller classification; however, an appropriate feature set is required to avoid high computational costs and the inclusion of irrelevant features. The objectives of this study were to identify and evaluate smaller feature sets for faller classification from large feature sets derived from wearable accelerometer and pressure-sensing insole gait data. A convenience sample of 100 older adults (75.5 ± 6.7 years; 76 non-fallers, 24 fallers based on 6 month retrospective fall occurrence) walked 7.62 m while wearing pressure-sensing insoles and tri-axial accelerometers at the head, pelvis, left and right shanks. Feature selection was performed using correlation-based feature selection (CFS), fast correlation based filter (FCBF), and Relief-F algorithms. Faller classification was performed using multi-layer perceptron neural network, naïve Bayesian, and support vector machine classifiers, with 75:25 single stratified holdout and repeated random sampling. The best performing model was a support vector machine with 78% accuracy, 26% sensitivity, 95% specificity, 0.36 F1 score, and 0.31 MCC and one posterior pelvis accelerometer input feature (left acceleration standard deviation). The second best model achieved better sensitivity (44%) and used a support vector machine with 74% accuracy, 83% specificity, 0.44 F1 score, and 0.29 MCC. This model had ten input features: maximum, mean and standard deviation posterior acceleration; maximum, mean and standard deviation anterior acceleration; mean superior acceleration; and three impulse features. The best multi-sensor model sensitivity (56%) was achieved using posterior pelvis and both shank accelerometers and a naïve Bayesian classifier. The best single-sensor model sensitivity (41%) was achieved using the posterior pelvis accelerometer and a naïve Bayesian classifier. Feature selection provided models with smaller feature sets and improved faller classification compared to faller classification without feature selection. CFS and FCBF provided the best feature subset (one posterior pelvis accelerometer feature) for faller classification. However, better sensitivity was achieved by the second best model based on a Relief-F feature subset with three pressure-sensing insole features and seven head accelerometer features. Feature selection should be considered as an important step in faller classification using wearable sensors.

  1. Simulation-based estimation of mean and standard deviation for meta-analysis via Approximate Bayesian Computation (ABC).

    PubMed

    Kwon, Deukwoo; Reis, Isildinha M

    2015-08-12

    When conducting a meta-analysis of a continuous outcome, estimated means and standard deviations from the selected studies are required in order to obtain an overall estimate of the mean effect and its confidence interval. If these quantities are not directly reported in the publications, they must be estimated from other reported summary statistics, such as the median, the minimum, the maximum, and quartiles. We propose a simulation-based estimation approach using the Approximate Bayesian Computation (ABC) technique for estimating mean and standard deviation based on various sets of summary statistics found in published studies. We conduct a simulation study to compare the proposed ABC method with the existing methods of Hozo et al. (2005), Bland (2015), and Wan et al. (2014). In the estimation of the standard deviation, our ABC method performs better than the other methods when data are generated from skewed or heavy-tailed distributions. The corresponding average relative error (ARE) approaches zero as sample size increases. In data generated from the normal distribution, our ABC performs well. However, the Wan et al. method is best for estimating standard deviation under normal distribution. In the estimation of the mean, our ABC method is best regardless of assumed distribution. ABC is a flexible method for estimating the study-specific mean and standard deviation for meta-analysis, especially with underlying skewed or heavy-tailed distributions. The ABC method can be applied using other reported summary statistics such as the posterior mean and 95 % credible interval when Bayesian analysis has been employed.

  2. Automatic estimation of dynamics of ionospheric disturbances with 1–15 minute lifetimes as derived from ISTP SB RAS fast chirp-ionosonde data

    NASA Astrophysics Data System (ADS)

    Berngardt, Oleg; Bubnova, Tatyana; Podlesnyi, Aleksey

    2018-03-01

    We propose and test a method of analyzing ionograms of vertical ionospheric sounding, which is based on detecting deviations of the shape of an ionogram from its regular (averaged) shape. We interpret these deviations in terms of reflection from the electron density irregularities at heights corresponding to the effective height. We examine the irregularities thus discovered within the framework of a model of a localized uniformly moving irregularity, and determine their characteristic parameters: effective heights and observed vertical velocities. We analyze selected experimental data for three seasons (spring, winter, autumn) obtained nearby Irkutsk with a fast chirp ionosonde of ISTP SB RAS in 2013-2015. The analysis of six days of observations conducted in these seasons has shown that in the observed vertical drift of the irregularities there are two characteristic distributions: wide velocity distribution with nearly 0 m/s mean and with the standard deviation of ∼250 m/s and narrow distribution with nearly -160 m/s mean. The analysis has demonstrated the effectiveness of the proposed algorithm for the automatic analysis of vertical sounding data with high repetition rate.

  3. Odontometric evaluation of mandibular premolars with tooth shape deviation: a case-control study.

    PubMed

    Chate, Robert Anthony Clive

    2012-09-01

    To evaluate the mean dimensions and morphologic characteristics of mandibular premolars that had mesiodistally elongated and faciolingually squeezed tooth shape deviations (MnP-TSD) and determine the population prevalence of this anomaly. Clinical photographs and study models were made for all new patients with MnP-TSD teeth who were seen over 20 years. The mesiodistal (MD) and faciolingual (FL) dimensions of the anomalous premolars were measured. MD/FL indices and MD × FL mm(2) occlusal crown areas were calculated and means and standard deviations were derived. Male and female means from the mandibular first and second anomalous premolars (MnP1/MnP2-TSD) were statistically compared against gender-specific means derived from published normative data using Student's t-tests and chi-square tests. Fifty-six individuals (33 male and 23 female) with MnP-TSD were identified, giving a male to female ratio of 1.4:1, while the prevalence rate in the indigenous British population was estimated to be 0.6%. The MD widths of the MnP1-TSD and MnP2-TSD teeth were approximately 1 mm wider than normal, while the FL diameters were about 0.5 mm and 1.5 mm narrower respectively, for the first and second premolar teeth. The MD/FL indices, instead of being under 90 as usual were above 100, while the mean MD/FL mm(2) crown surface areas were normal. This study supplies odontometric dimensional and morphologic data on MnP-TSD teeth that provide a reference source for future comparisons.

  4. On Teaching about the Coefficient of Variation in Introductory Statistics Courses

    ERIC Educational Resources Information Center

    Trafimow, David

    2014-01-01

    The standard deviation is related to the mean by virtue of the coefficient of variation. Teachers of statistics courses can make use of that fact to make the standard deviation more comprehensible for statistics students.

  5. Enhancing active and passive remote sensing in the ocean using broadband acoustic transmissions and coherent hydrophone arrays

    NASA Astrophysics Data System (ADS)

    Tran, Duong Duy

    The statistics of broadband acoustic signal transmissions in a random continental shelf waveguide are characterized for the fully saturated regime. The probability distribution of broadband signal energies after saturated multi-path propagation is derived using coherence theory. The frequency components obtained from Fourier decomposition of a broadband signal are each assumed to be fully saturated, where the energy spectral density obeys the exponential distribution with 5.6 dB standard deviation and unity scintillation index. When the signal bandwidth and measurement time are respectively larger than the correlation bandwidth and correlation time of its energy spectral density components, the broadband signal energy obtained by integrating the energy spectral density across the signal bandwidth then follows the Gamma distribution with standard deviation smaller than 5.6 dB and scintillation index less than unity. The theory is verified with broadband transmissions in the Gulf of Maine shallow water waveguide in the 300-1200 Hz frequency range. The standard deviations of received broadband signal energies range from 2.7 to 4.6 dB for effective bandwidths up to 42 Hz, while the standard deviations of individual energy spectral density components are roughly 5.6 dB. The energy spectral density correlation bandwidths of the received broadband signals are found to be larger for signals with higher center frequency. Sperm whales in the New England continental shelf and slope were passively localized, in both range and bearing using a single low-frequency (< 2500 Hz), densely sampled, towed horizontal coherent hydrophone array system. Whale bearings were estimated using time-domain beamforming that provided high coherent array gain in sperm whale click signal-to-noise ratio. Whale ranges from the receiver array center were estimated using the moving array triangulation technique from a sequence of whale bearing measurements. The dive profile was estimated for a sperm whale in the shallow waters of the Gulf of Maine with 160 m water-column depth, located close to the array's near-field where depth estimation was feasible by employing time difference of arrival of the direct and multiply reflected click signals received on the array. The dependence of broadband energy on bandwidth and measurement time was verified employing recorded sperm whale clicks in the Gulf of Maine.

  6. Comparison of spectral estimators for characterizing fractionated atrial electrograms

    PubMed Central

    2013-01-01

    Background Complex fractionated atrial electrograms (CFAE) acquired during atrial fibrillation (AF) are commonly assessed using the discrete Fourier transform (DFT), but this can lead to inaccuracy. In this study, spectral estimators derived by averaging the autocorrelation function at lags were compared to the DFT. Method Bipolar CFAE of at least 16 s duration were obtained from pulmonary vein ostia and left atrial free wall sites (9 paroxysmal and 10 persistent AF patients). Power spectra were computed using the DFT and three other methods: 1. a novel spectral estimator based on signal averaging (NSE), 2. the NSE with harmonic removal (NSH), and 3. the autocorrelation function average at lags (AFA). Three spectral parameters were calculated: 1. the largest fundamental spectral peak, known as the dominant frequency (DF), 2. the DF amplitude (DA), and 3. the mean spectral profile (MP), which quantifies noise floor level. For each spectral estimator and parameter, the significance of the difference between paroxysmal and persistent AF was determined. Results For all estimators, mean DA and mean DF values were higher in persistent AF, while the mean MP value was higher in paroxysmal AF. The differences in means between paroxysmals and persistents were highly significant for 3/3 NSE and NSH measurements and for 2/3 DFT and AFA measurements (p<0.001). For all estimators, the standard deviation in DA and MP values were higher in persistent AF, while the standard deviation in DF value was higher in paroxysmal AF. Differences in standard deviations between paroxysmals and persistents were highly significant in 2/3 NSE and NSH measurements, in 1/3 AFA measurements, and in 0/3 DFT measurements. Conclusions Measurements made from all four spectral estimators were in agreement as to whether the means and standard deviations in three spectral parameters were greater in CFAEs acquired from paroxysmal or in persistent AF patients. Since the measurements were consistent, use of two or more of these estimators for power spectral analysis can be assistive to evaluate CFAE more objectively and accurately, which may lead to improved clinical outcome. Since the most significant differences overall were achieved using the NSE and NSH estimators, parameters measured from their spectra will likely be the most useful for detecting and discerning electrophysiologic differences in the AF substrate based upon frequency analysis of CFAE. PMID:23855345

  7. Comparing Methods for Cardiac Output: Intraoperatively Doppler-Derived Cardiac Output Measured With 3-Dimensional Echocardiography Is Not Interchangeable With Cardiac Output by Pulmonary Catheter Thermodilution.

    PubMed

    Graeser, Karin; Zemtsovski, Mikhail; Kofoed, Klaus F; Winther-Jensen, Matilde; Nilsson, Jens C; Kjaergaard, Jesper; Møller-Sørensen, Hasse

    2018-01-09

    Estimation of cardiac output (CO) is essential in the treatment of circulatory unstable patients. CO measured by pulmonary artery catheter thermodilution is considered the gold standard but carries a small risk of severe complications. Stroke volume and CO can be measured by transesophageal echocardiography (TEE), which is widely used during cardiac surgery. We hypothesized that Doppler-derived CO by 3-dimensional (3D) TEE would agree well with CO measured with pulmonary artery catheter thermodilution as a reference method based on accurate measurements of the cross-sectional area of the left ventricular outflow tract. The primary aim was a systematic comparison of CO with Doppler-derived 3D TEE and CO by thermodilution in a broad population of patients undergoing cardiac surgery. A subanalysis was performed comparing cross-sectional area by TEE with cardiac computed tomography (CT) angiography. Sixty-two patients, scheduled for elective heart surgery, were included; 1 was subsequently excluded for logistic reasons. Inclusion criteria were coronary artery bypass surgery (N = 42) and aortic valve replacement (N = 19). Exclusion criteria were chronic atrial fibrillation, left ventricular ejection fraction below 0.40 and intracardiac shunts. Nineteen randomly selected patients had a cardiac CT the day before surgery. All images were stored for blinded post hoc analyses, and Bland-Altman plots were used to assess agreement between measurement methods, defined as the bias (mean difference between methods), limits of agreement (equal to bias ± 2 standard deviations of the bias), and percentage error (limits of agreement divided by the mean of the 2 methods). Precision was determined for the individual methods (equal to 2 standard deviations of the bias between replicate measurements) to determine the acceptable limits of agreement. We found a good precision for Doppler-derived CO measured by 3D TEE, but although the bias for Doppler-derived CO by 3D compared to thermodilution was only 0.3 L/min (confidence interval, 0.04-0.58), there were wide limits of agreement (-1.8 to 2.5 L/min) with a percentage error of 55%. Measurements of cross-sectional area by 3D TEE had low bias of -0.27 cm (confidence interval, -0.45 to -0.08) and a percentage error of 18% compared to cardiac CT angiography. Despite low bias, the wide limits of agreement of Doppler-derived CO by 3D TEE compared to CO by thermodilution will limit clinical application and can therefore not be considered interchangeable with CO obtained by thermodilution. The lack of agreement is not explained by lack of agreement of the 3D technique.

  8. A SIMPLE METHOD FOR EVALUATING DATA FROM AN INTERLABORATORY STUDY

    EPA Science Inventory

    Large-scale laboratory-and method-performance studies involving more than about 30 laboratories may be evaluated by calculating the HORRAT ratio for each test sample (HORRAT=[experimentally found among-laboratories relative standard deviation] divided by [relative standard deviat...

  9. Histogram-based quantitative evaluation of endobronchial ultrasonography images of peripheral pulmonary lesion.

    PubMed

    Morikawa, Kei; Kurimoto, Noriaki; Inoue, Takeo; Mineshita, Masamichi; Miyazawa, Teruomi

    2015-01-01

    Endobronchial ultrasonography using a guide sheath (EBUS-GS) is an increasingly common bronchoscopic technique, but currently, no methods have been established to quantitatively evaluate EBUS images of peripheral pulmonary lesions. The purpose of this study was to evaluate whether histogram data collected from EBUS-GS images can contribute to the diagnosis of lung cancer. Histogram-based analyses focusing on the brightness of EBUS images were retrospectively conducted: 60 patients (38 lung cancer; 22 inflammatory diseases), with clear EBUS images were included. For each patient, a 400-pixel region of interest was selected, typically located at a 3- to 5-mm radius from the probe, from recorded EBUS images during bronchoscopy. Histogram height, width, height/width ratio, standard deviation, kurtosis and skewness were investigated as diagnostic indicators. Median histogram height, width, height/width ratio and standard deviation were significantly different between lung cancer and benign lesions (all p < 0.01). With a cutoff value for standard deviation of 10.5, lung cancer could be diagnosed with an accuracy of 81.7%. Other characteristics investigated were inferior when compared to histogram standard deviation. Histogram standard deviation appears to be the most useful characteristic for diagnosing lung cancer using EBUS images. © 2015 S. Karger AG, Basel.

  10. Role of the standard deviation in the estimation of benchmark doses with continuous data.

    PubMed

    Gaylor, David W; Slikker, William

    2004-12-01

    For continuous data, risk is defined here as the proportion of animals with values above a large percentile, e.g., the 99th percentile or below the 1st percentile, for the distribution of values among control animals. It is known that reducing the standard deviation of measurements through improved experimental techniques will result in less stringent (higher) doses for the lower confidence limit on the benchmark dose that is estimated to produce a specified risk of animals with abnormal levels for a biological effect. Thus, a somewhat larger (less stringent) lower confidence limit is obtained that may be used as a point of departure for low-dose risk assessment. It is shown in this article that it is important for the benchmark dose to be based primarily on the standard deviation among animals, s(a), apart from the standard deviation of measurement errors, s(m), within animals. If the benchmark dose is incorrectly based on the overall standard deviation among average values for animals, which includes measurement error variation, the benchmark dose will be overestimated and the risk will be underestimated. The bias increases as s(m) increases relative to s(a). The bias is relatively small if s(m) is less than one-third of s(a), a condition achieved in most experimental designs.

  11. Statistical models for estimating daily streamflow in Michigan

    USGS Publications Warehouse

    Holtschlag, D.J.; Salehi, Habib

    1992-01-01

    Statistical models for estimating daily streamflow were analyzed for 25 pairs of streamflow-gaging stations in Michigan. Stations were paired by randomly choosing a station operated in 1989 at which 10 or more years of continuous flow data had been collected and at which flow is virtually unregulated; a nearby station was chosen where flow characteristics are similar. Streamflow data from the 25 randomly selected stations were used as the response variables; streamflow data at the nearby stations were used to generate a set of explanatory variables. Ordinary-least squares regression (OLSR) equations, autoregressive integrated moving-average (ARIMA) equations, and transfer function-noise (TFN) equations were developed to estimate the log transform of flow for the 25 randomly selected stations. The precision of each type of equation was evaluated on the basis of the standard deviation of the estimation errors. OLSR equations produce one set of estimation errors; ARIMA and TFN models each produce l sets of estimation errors corresponding to the forecast lead. The lead-l forecast is the estimate of flow l days ahead of the most recent streamflow used as a response variable in the estimation. In this analysis, the standard deviation of lead l ARIMA and TFN forecast errors were generally lower than the standard deviation of OLSR errors for l < 2 days and l < 9 days, respectively. Composite estimates were computed as a weighted average of forecasts based on TFN equations and backcasts (forecasts of the reverse-ordered series) based on ARIMA equations. The standard deviation of composite errors varied throughout the length of the estimation interval and generally was at maximum near the center of the interval. For comparison with OLSR errors, the mean standard deviation of composite errors were computed for intervals of length 1 to 40 days. The mean standard deviation of length-l composite errors were generally less than the standard deviation of the OLSR errors for l < 32 days. In addition, the composite estimates ensure a gradual transition between periods of estimated and measured flows. Model performance among stations of differing model error magnitudes were compared by computing ratios of the mean standard deviation of the length l composite errors to the standard deviation of OLSR errors. The mean error ratio for the set of 25 selected stations was less than 1 for intervals l < 32 days. Considering the frequency characteristics of the length of intervals of estimated record in Michigan, the effective mean error ratio for intervals < 30 days was 0.52. Thus, for intervals of estimation of 1 month or less, the error of the composite estimate is substantially lower than error of the OLSR estimate.

  12. Comment on the paper "Mars Express radio occultation data: A novel analysis approach" by Grandin et al. (2014)

    NASA Astrophysics Data System (ADS)

    Pätzold, M.; Bird, M. K.; Häusler, B.; Peter, K.; Tellmann, S.; Tyler, G. L.

    2016-10-01

    In their recent paper, Grandin et al. (2014) claim to have developed a novel approach, principally a ray tracing method, to analyze radio sounding data from occulted spacecraft signals by planetary atmospheres without the usual assumptions of the radio occultation inversion method of a stratified, layered, symmetric atmosphere. They apply their "new approach" to observations of the Mars Express Radio Science (MaRS) experiment and compare their resulting temperature, neutral number density, and electron density profiles with those from MaRS, claiming that there is good agreement with the observations. The fact is, however, that there are serious disagreements in the most important altitude ranges. Their temperature profile shows a 30 K shift or a 300σ (1σ standard deviation = 0.1 K for the MaRS profile near the surface) difference toward warmer temperatures at the surface when compared with MaRS, while the MaRS profile is in best agreement with the profile from the Mars Climate Data Base V5.0 (MCD V5.0). Their full temperature profile from the surface to 250 km altitude deviates significantly from the MCD V5.0 profile. Their ionospheric electron density profile is considerably different from that derived from the MaRs observations. Although Grandin et al. (2014) claim to derive the neutral number density and temperature profiles above 200 km, including the asymptotic exosphere temperature, it is simply not possible to derive this information from what is essentially noise.

  13. Definition of new cut‐offs of BMI and waist circumference based on body composition and insulin resistance: differences between children, adolescents and adults

    PubMed Central

    Hübers, M.; Pourhassan, M.; Braun, W.; Geisler, C.

    2017-01-01

    Summary Objective This study aims to determine associations between anthropometric traits, regional fat depots and insulin resistance in children, adolescents and adults to define new cut‐offs of body mass index (BMI) or waist circumference (WC). Design Cross‐sectional data were assessed in 433 children, adolescents and adults (aged: 6–60 years, BMI: 23.6 [21.0–27.7] kg m−2). Total adipose tissue (TAT), regional subcutaneous adipose tissue (SATtotal, SATtrunk) and visceral adipose tissue (VAT) were determined by whole‐body magnetic resonance imaging, fat mass by air‐displacement plethysmography. Insulin resistance was evaluated by homeostasis model assessment of insulin resistance (HOMA‐IR). Bivariate as well as partial correlations and regression analyses were used. Cut‐off values of BMI and WC related to regional fat depots and HOMA‐IR were analysed by receiver operating characteristics curve. Results In adults, TAT, SATtotal and SATtrunk increased linearly with increasing BMI and WC, whereas they followed a cubic function in children and adolescents with a steep increase at BMI and WC ≥1 standard deviation score and VAT at WC ≥2 standard deviation score. Sex differences were apparent in adults with women having higher masses of TAT and SAT and men having higher VAT. Using established BMI or WC cut‐offs, correspondent masses of TAT, SATtotal, SATtrunk and VAT increased from childhood to adulthood. In all age groups, there were positive associations between BMI, WC, SATtrunk, VAT and HOMA‐IR. When compared with normative cut‐offs of BMI or WC, HOMA‐IR‐derived cut‐offs of regional fat depots were lower in all age groups. Conclusions Associations between BMI, WC and regional fat depots varied between children, adolescents, young and older adults. When compared with BMI‐derived and WC‐derived values, an insulin resistance‐derived cut‐off corresponded to lower masses of regional fat depots. Thus, established BMI and WC cut‐offs are not appropriate to assess metabolic disturbances associated with obesity; therefore, new cut‐offs of BMI and WC are needed for clinical practice. PMID:29071103

  14. Momentum and heat flux estimation in the planetary boundary layer (PBL) with a 10.6-micron Doppler lidar

    NASA Technical Reports Server (NTRS)

    Gal-Chen, Tzvi; Xu, Mei; Eberhard, Wynn

    1991-01-01

    The mean wind, its standard deviation, and the momentum fluxes in the PBL are estimated with a 10.6-micron Doppler lidar. Spectral analysis of the radial velocities was performed, from which, by examining the amplitude of the power spectrum at the inertial range, the kinetic energy dissipation was deduced. The statistical form of the Navier-Stokes equations was used to derive the surface heat flux as the residual balance between the vertical gradient of the third moment of the vertical velocity and the kinetic energy dissipation.

  15. feets: feATURE eXTRACTOR for tIME sERIES

    NASA Astrophysics Data System (ADS)

    Cabral, Juan; Sanchez, Bruno; Ramos, Felipe; Gurovich, Sebastián; Granitto, Pablo; VanderPlas, Jake

    2018-06-01

    feets characterizes and analyzes light-curves from astronomical photometric databases for modelling, classification, data cleaning, outlier detection and data analysis. It uses machine learning algorithms to determine the numerical descriptors that characterize and distinguish the different variability classes of light-curves; these range from basic statistical measures such as the mean or standard deviation to complex time-series characteristics such as the autocorrelation function. The library is not restricted to the astronomical field and could also be applied to any kind of time series. This project is a derivative work of FATS (ascl:1711.017).

  16. Heat flow in chains driven by thermal noise

    NASA Astrophysics Data System (ADS)

    Fogedby, Hans C.; Imparato, Alberto

    2012-04-01

    We consider the large deviation function for a classical harmonic chain composed of N particles driven at the end points by heat reservoirs, first derived in the quantum regime by Saito and Dhar (2007 Phys. Rev. Lett. 99 180601) and in the classical regime by Saito and Dhar (2011 Phys. Rev. E 83 041121) and Kundu et al (2011 J. Stat. Mech. P03007). Within a Langevin description we perform this calculation on the basis of a standard path integral calculation in Fourier space. The cumulant generating function yielding the large deviation function is given in terms of a transmission Green's function and is consistent with the fluctuation theorem. We find a simple expression for the tails of the heat distribution, which turns out to decay exponentially. We, moreover, consider an extension of a single-particle model suggested by Derrida and Brunet (2005 Einstein Aujourd'hui (Les Ulis: EDP Sciences)) and discuss the two-particle case. We also discuss the limit for large N and present a closed expression for the cumulant generating function. Finally, we present a derivation of the fluctuation theorem on the basis of a Fokker-Planck description. This result is not restricted to the harmonic case but is valid for a general interaction potential between the particles.

  17. 10 CFR 961.4 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Deviations. 961.4 Section 961.4 Energy DEPARTMENT OF ENERGY STANDARD CONTRACT FOR DISPOSAL OF SPENT NUCLEAR FUEL AND/OR HIGH-LEVEL RADIOACTIVE WASTE General § 961.4 Deviations. Requests for authority to deviate from this part shall be submitted in writing to...

  18. 10 CFR 961.4 - Deviations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Deviations. 961.4 Section 961.4 Energy DEPARTMENT OF ENERGY STANDARD CONTRACT FOR DISPOSAL OF SPENT NUCLEAR FUEL AND/OR HIGH-LEVEL RADIOACTIVE WASTE General § 961.4 Deviations. Requests for authority to deviate from this part shall be submitted in writing to...

  19. 10 CFR 961.4 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Deviations. 961.4 Section 961.4 Energy DEPARTMENT OF ENERGY STANDARD CONTRACT FOR DISPOSAL OF SPENT NUCLEAR FUEL AND/OR HIGH-LEVEL RADIOACTIVE WASTE General § 961.4 Deviations. Requests for authority to deviate from this part shall be submitted in writing to...

  20. 10 CFR 961.4 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Deviations. 961.4 Section 961.4 Energy DEPARTMENT OF ENERGY STANDARD CONTRACT FOR DISPOSAL OF SPENT NUCLEAR FUEL AND/OR HIGH-LEVEL RADIOACTIVE WASTE General § 961.4 Deviations. Requests for authority to deviate from this part shall be submitted in writing to...

  1. 10 CFR 961.4 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Deviations. 961.4 Section 961.4 Energy DEPARTMENT OF ENERGY STANDARD CONTRACT FOR DISPOSAL OF SPENT NUCLEAR FUEL AND/OR HIGH-LEVEL RADIOACTIVE WASTE General § 961.4 Deviations. Requests for authority to deviate from this part shall be submitted in writing to...

  2. Do health care workforce, population, and service provision significantly contribute to the total health expenditure? An econometric analysis of Serbia.

    PubMed

    Santric-Milicevic, M; Vasic, V; Terzic-Supic, Z

    2016-08-15

    In times of austerity, the availability of econometric health knowledge assists policy-makers in understanding and balancing health expenditure with health care plans within fiscal constraints. The objective of this study is to explore whether the health workforce supply of the public health care sector, population number, and utilization of inpatient care significantly contribute to total health expenditure. The dependent variable is the total health expenditure (THE) in Serbia from the years 2003 to 2011. The independent variables are the number of health workers employed in the public health care sector, population number, and inpatient care discharges per 100 population. The statistical analyses include the quadratic interpolation method, natural logarithm and differentiation, and multiple linear regression analyses. The level of significance is set at P < 0.05. The regression model captures 90 % of all variations of observed dependent variables (adjusted R square), and the model is significant (P < 0.001). Total health expenditure increased by 1.21 standard deviations, with an increase in health workforce growth rate by 1 standard deviation. Furthermore, this rate decreased by 1.12 standard deviations, with an increase in (negative) population growth rate by 1 standard deviation. Finally, the growth rate increased by 0.38 standard deviation, with an increase of the growth rate of inpatient care discharges per 100 population by 1 standard deviation (P < 0.001). Study results demonstrate that the government has been making an effort to control strongly health budget growth. Exploring causality relationships between health expenditure and health workforce is important for countries that are trying to consolidate their public health finances and achieve universal health coverage at the same time.

  3. Interpretability of the PedsQL™ Gastrointestinal Symptoms Scales and Gastrointestinal Worry Scales in Pediatric Patients With Functional and Organic Gastrointestinal Diseases

    PubMed Central

    Bendo, Cristiane B.; Shulman, Robert J.; Self, Mariella M.; Nurko, Samuel; Franciosi, James P.; Saps, Miguel; Saeed, Shehzad; Zacur, George M.; Vaughan Dark, Chelsea; Pohl, John F.

    2015-01-01

    Objective The present study investigates the clinical interpretability of the Pediatric Quality of Life Inventory™ (PedsQL™) Gastrointestinal Symptoms Scales and Worry Scales in pediatric patients with functional gastrointestinal disorders or organic gastrointestinal diseases in comparison with healthy controls. Methods The PedsQL™ Gastrointestinal Scales were completed by 587 patients with gastrointestinal disorders/diseases and 685 parents, and 513 healthy children and 337 parents. Minimal important difference (MID) scores were derived from the standard error of measurement (SEM). Cut-points were derived based on one and two standard deviations (SDs) from the healthy reference means. Results The percentages of patients below the scales’ cut-points were significantly greater than the healthy controls (most p values ≤ .001). Scale scores 2 SDs from the healthy reference means were within the range of scores for pediatric patients with a gastrointestinal disorder. MID values were generated using the SEM. Conclusions The findings support the clinical interpretability of the new PedsQL™ Gastrointestinal Symptoms Scales and Worry Scales. PMID:25682210

  4. Asymmetric Membranes from Two Chemically Distinct Triblock Terpolymers Blended during Standard Membrane Fabrication.

    PubMed

    Li, Yuk Mun; Srinivasan, Divya; Vaidya, Parth; Gu, Yibei; Wiesner, Ulrich

    2016-10-01

    Deviating from the traditional formation of block copolymer derived isoporous membranes from one block copolymer chemistry, here asymmetric membranes with isoporous surface structure are derived from two chemically distinct block copolymers blended during standard membrane fabrication. As a first proof of principle, the fabrication of asymmetric membranes is reported, which are blended from two chemically distinct triblock terpolymers, poly(isoprene-b-styrene-b-(4-vinyl)pyridine) (ISV) and poly(isoprene-b-styrene-b-(dimethylamino)ethyl methacrylate) (ISA), differing in the pH-responsive hydrophilic segment. Using block copolymer self-assembly and nonsolvent induced phase separation process, pure and blended membranes are prepared by varying weight ratios of ISV to ISA. Pure and blended membranes exhibit a thin, selective layer of pores above a macroporous substructure. Observed permeabilities at varying pH values of blended membranes depend on relative triblock terpolymer composition. These results open a new direction for membrane fabrication through the use of mixtures of chemically distinct block copolymers enabling the tailoring of membrane surface chemistries and functionalities. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Analysis of hydrazine in drinking water by isotope dilution gas chromatography/tandem mass spectrometry with derivatization and liquid-liquid extraction.

    PubMed

    Davis, William E; Li, Yongtao

    2008-07-15

    A new isotope dilution gas chromatography/chemical ionization/tandem mass spectrometric method was developed for the analysis of carcinogenic hydrazine in drinking water. The sample preparation was performed by using the optimized derivatization and multiple liquid-liquid extraction techniques. Using the direct aqueous-phase derivatization with acetone, hydrazine and isotopically labeled hydrazine-(15)N2 used as the surrogate standard formed acetone azine and acetone azine-(15)N2, respectively. These derivatives were then extracted with dichloromethane. Prior to analysis using methanol as the chemical ionization reagent gas, the extract was dried with anhydrous sodium sulfate, concentrated through evaporation, and then fortified with isotopically labeled N-nitrosodimethylamine-d6 used as the internal standard to quantify the extracted acetone azine-(15)N2. The extracted acetone azine was quantified against the extracted acetone azine-(15)N2. The isotope dilution standard calibration curve resulted in a linear regression correlation coefficient (R) of 0.999. The obtained method detection limit was 0.70 ng/L for hydrazine in reagent water samples, fortified at a concentration of 1.0 ng/L. For reagent water samples fortified at a concentration of 20.0 ng/L, the mean recoveries were 102% with a relative standard deviation of 13.7% for hydrazine and 106% with a relative standard deviation of 12.5% for hydrazine-(15)N2. Hydrazine at 0.5-2.6 ng/L was detected in 7 out of 13 chloraminated drinking water samples but was not detected in the rest of the chloraminated drinking water samples and the studied chlorinated drinking water sample.

  6. Pulse oximetry-derived respiratory rate in general care floor patients.

    PubMed

    Addison, Paul S; Watson, James N; Mestek, Michael L; Ochs, James P; Uribe, Alberto A; Bergese, Sergio D

    2015-02-01

    Respiratory rate is recognized as a clinically important parameter for monitoring respiratory status on the general care floor (GCF). Currently, intermittent manual assessment of respiratory rate is the standard of care on the GCF. This technique has several clinically-relevant shortcomings, including the following: (1) it is not a continuous measurement, (2) it is prone to observer error, and (3) it is inefficient for the clinical staff. We report here on an algorithm designed to meet clinical needs by providing respiratory rate through a standard pulse oximeter. Finger photoplethysmograms were collected from a cohort of 63 GCF patients monitored during free breathing over a 25-min period. These were processed using a novel in-house algorithm based on continuous wavelet-transform technology within an infrastructure incorporating confidence-based averaging and logical decision-making processes. The computed oximeter respiratory rates (RRoxi) were compared to an end-tidal CO2 reference rate (RRETCO2). RRETCO2 ranged from a lowest recorded value of 4.7 breaths per minute (brpm) to a highest value of 32.0 brpm. The mean respiratory rate was 16.3 brpm with standard deviation of 4.7 brpm. Excellent agreement was found between RRoxi and RRETCO2, with a mean difference of -0.48 brpm and standard deviation of 1.77 brpm. These data demonstrate that our novel respiratory rate algorithm is a potentially viable method of monitoring respiratory rate in GCF patients. This technology provides the means to facilitate continuous monitoring of respiratory rate, coupled with arterial oxygen saturation and pulse rate, using a single non-invasive sensor in low acuity settings.

  7. Scan-To Output Validation: Towards a Standardized Geometric Quality Assessment of Building Information Models Based on Point Clouds

    NASA Astrophysics Data System (ADS)

    Bonduel, M.; Bassier, M.; Vergauwen, M.; Pauwels, P.; Klein, R.

    2017-11-01

    The use of Building Information Modeling (BIM) for existing buildings based on point clouds is increasing. Standardized geometric quality assessment of the BIMs is needed to make them more reliable and thus reusable for future users. First, available literature on the subject is studied. Next, an initial proposal for a standardized geometric quality assessment is presented. Finally, this method is tested and evaluated with a case study. The number of specifications on BIM relating to existing buildings is limited. The Levels of Accuracy (LOA) specification of the USIBD provides definitions and suggestions regarding geometric model accuracy, but lacks a standardized assessment method. A deviation analysis is found to be dependent on (1) the used mathematical model, (2) the density of the point clouds and (3) the order of comparison. Results of the analysis can be graphical and numerical. An analysis on macro (building) and micro (BIM object) scale is necessary. On macro scale, the complete model is compared to the original point cloud and vice versa to get an overview of the general model quality. The graphical results show occluded zones and non-modeled objects respectively. Colored point clouds are derived from this analysis and integrated in the BIM. On micro scale, the relevant surface parts are extracted per BIM object and compared to the complete point cloud. Occluded zones are extracted based on a maximum deviation. What remains is classified according to the LOA specification. The numerical results are integrated in the BIM with the use of object parameters.

  8. The truly remarkable universality of half a standard deviation: confirmation through another look.

    PubMed

    Norman, Geoffrey R; Sloan, Jeff A; Wyrwich, Kathleen W

    2004-10-01

    In this issue of Expert Review of Pharmacoeconomics and Outcomes Research, Farivar, Liu, and Hays present their findings in 'Another look at the half standard deviation estimate of the minimally important difference in health-related quality of life scores (hereafter referred to as 'Another look') . These researchers have re-examined the May 2003 Medical Care article 'Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation' (hereafter referred to as 'Remarkable') in the hope of supporting their hypothesis that the minimally important difference in health-related quality of life measures is undoubtedly closer to 0.3 standard deviations than 0.5. Nonetheless, despite their extensive wranglings with the exclusion of many articles that we included in our review; the inclusion of articles that we did not include in our review; and the recalculation of effect sizes using the absolute value of the mean differences, in our opinion, the results of the 'Another look' article confirm the same findings in the 'Remarkable' paper.

  9. Static Scene Statistical Non-Uniformity Correction

    DTIC Science & Technology

    2015-03-01

    Error NUC Non-Uniformity Correction RMSE Root Mean Squared Error RSD Relative Standard Deviation S3NUC Static Scene Statistical Non-Uniformity...Deviation ( RSD ) which normalizes the standard deviation, σ, to the mean estimated value, µ using the equation RS D = σ µ × 100. The RSD plot of the gain...estimates is shown in Figure 4.1(b). The RSD plot shows that after a sample size of approximately 10, the different photocount values and the inclusion

  10. Effect of multizone refractive multifocal contact lenses on standard automated perimetry.

    PubMed

    Madrid-Costa, David; Ruiz-Alcocer, Javier; García-Lázaro, Santiago; Albarrán-Diego, César; Ferrer-Blasco, Teresa

    2012-09-01

    The aim of this study was to evaluate whether the creation of 2 foci (distance and near) provided by multizone refractive multifocal contact lenses (CLs) for presbyopia correction affects the measurements on Humphreys 24-2 Swedish interactive threshold algorithm (SITA) standard automated perimetry (SAP). In this crossover study, 30 subjects were fitted in random order with either a multifocal CL or a monofocal CL. After 1 month, a Humphrey 24-2 SITA standard strategy was performed. The visual field global indices (the mean deviation [MD] and pattern standard deviation [PSD]), reliability indices, test duration, and number of depressed points deviating at P<5%, P<2%, P<1%, and P<0.5% on pattern deviation probability plots were determined and compared between multifocal and monofocal CLs. Thirty eyes of 30 subjects were included in this study. There were no statistically significant differences in reliability indices or test duration. There was a statistically significant reduction in the MD with the multifocal CL compared with monfocal CL (P=0.001). Differences were not found in PSD nor in the number of depressed points deviating at P<5%, P<2%, P<1%, and P<0.5% in the pattern deviation probability maps studied. The results of this study suggest that the multizone refractive lens produces a generalized depression in threshold sensitivity as measured by the Humphreys 24-2 SITA SAP.

  11. Quantifying social development in autism.

    PubMed

    Volkmar, F R; Carter, A; Sparrow, S S; Cicchetti, D V

    1993-05-01

    This study was concerned with the development of quantitative measures of social development in autism. Multiple regression equations predicting social, communicative, and daily living skills on the Vineland Adaptive Behavior Scales were derived from a large, normative sample and applied to groups of autistic and nonautistic, developmentally disordered children. Predictive models included either mental or chronological age and other relevant variables. Social skills in the autistic group were more than two standard deviations below those predicted by their mental age; an index derived from the ratio of actual to predicted social skills correctly classified 94% of the autistic and 92% of the nonautistic, developmentally disordered cases. The findings are consistent with the idea that social disturbance is central in the definition of autism. The approach used in this study has potential advantages for providing more precise measures of social development in autism.

  12. Monitoring of the fermentation media of citric acid by the trimethylsilyl derivatives of the organic acids formed.

    PubMed

    Ghassempour, Alireza; Nojavan, Saeed; Talebpour, Zahra; Amiri, Ali Asghar; Najafi, Nahid Mashkouri

    2004-10-20

    In this approach, a derivatization method is described for monitoring of organic acids in fermentation media without any separation step. The aqueous phase of fermentation media was evaporated and heated in a silylation reagent to form trimethylsilyl (TMS) derivatives. The silylated compounds are analyzed by 29Si nuclear magnetic resonance (29Si NMR) and gas chromatography-mass spectrometry (GC-MS). 29Si NMR can qualitatively monitor the components produced in the Krebs cycle. Quantification of these compounds is investigated by using selected ion monitoring mode of mass spectrometry. In this mode, mass to charge (m/z) values of their [M - 15]+ ions, which are 465, 275, 247, 221, 335, 251, and 313 of TMS derivatives of citric, alpha-ketoglutaric, succinic, fumaric, l-malic, oxaloacetic, and palmitic (as an internal standard), acids, respectively, are used. The limit of detection and the linear working range for derivatized citric acid were found to be 0.1 mg L(-1) and 10-3 x 10(4) mg L(-1). The relative standard deviation of the method for five replicates was 2.1%. The average recovery efficiency for citric acid added to culture media was approximately 97.2%. Quantitative results of GC-MS are compared with those obtained by an ultraviolet-visible method. Copyright 2004 American Chemical Society

  13. Investigation of the refractive index repeatability for tantalum pentoxide coatings, prepared by physical vapor film deposition techniques.

    PubMed

    Stenzel, O; Wilbrandt, S; Wolf, J; Schürmann, M; Kaiser, N; Ristau, D; Ehlers, H; Carstens, F; Schippel, S; Mechold, L; Rauhut, R; Kennedy, M; Bischoff, M; Nowitzki, T; Zöller, A; Hagedorn, H; Reus, H; Hegemann, T; Starke, K; Harhausen, J; Foest, R; Schumacher, J

    2017-02-01

    Random effects in the repeatability of refractive index and absorption edge position of tantalum pentoxide layers prepared by plasma-ion-assisted electron-beam evaporation, ion beam sputtering, and magnetron sputtering are investigated and quantified. Standard deviations in refractive index between 4*10-4 and 4*10-3 have been obtained. Here, lowest standard deviations in refractive index close to our detection threshold could be achieved by both ion beam sputtering and plasma-ion-assisted deposition. In relation to the corresponding mean values, the standard deviations in band-edge position and refractive index are of similar order.

  14. Closed-form confidence intervals for functions of the normal mean and standard deviation.

    PubMed

    Donner, Allan; Zou, G Y

    2012-08-01

    Confidence interval methods for a normal mean and standard deviation are well known and simple to apply. However, the same cannot be said for important functions of these parameters. These functions include the normal distribution percentiles, the Bland-Altman limits of agreement, the coefficient of variation and Cohen's effect size. We present a simple approach to this problem by using variance estimates recovered from confidence limits computed for the mean and standard deviation separately. All resulting confidence intervals have closed forms. Simulation results demonstrate that this approach performs very well for limits of agreement, coefficients of variation and their differences.

  15. Comparing biomarker measurements to a normal range: when to use standard error of the mean (SEM) or standard deviation (SD) confidence intervals tests.

    PubMed

    Pleil, Joachim D

    2016-01-01

    This commentary is the second of a series outlining one specific concept in interpreting biomarkers data. In the first, an observational method was presented for assessing the distribution of measurements before making parametric calculations. Here, the discussion revolves around the next step, the choice of using standard error of the mean or the calculated standard deviation to compare or predict measurement results.

  16. Acoustic response variability in automotive vehicles

    NASA Astrophysics Data System (ADS)

    Hills, E.; Mace, B. R.; Ferguson, N. S.

    2009-03-01

    A statistical analysis of a series of measurements of the audio-frequency response of a large set of automotive vehicles is presented: a small hatchback model with both a three-door (411 vehicles) and five-door (403 vehicles) derivative and a mid-sized family five-door car (316 vehicles). The sets included vehicles of various specifications, engines, gearboxes, interior trim, wheels and tyres. The tests were performed in a hemianechoic chamber with the temperature and humidity recorded. Two tests were performed on each vehicle and the interior cabin noise measured. In the first, the excitation was acoustically induced by sets of external loudspeakers. In the second test, predominantly structure-borne noise was induced by running the vehicle at a steady speed on a rough roller. For both types of excitation, it is seen that the effects of temperature are small, indicating that manufacturing variability is larger than that due to temperature for the tests conducted. It is also observed that there are no significant outlying vehicles, i.e. there are at most only a few vehicles that consistently have the lowest or highest noise levels over the whole spectrum. For the acoustically excited tests, measured 1/3-octave noise reduction levels typically have a spread of 5 dB or so and the normalised standard deviation of the linear data is typically 0.1 or higher. Regarding the statistical distribution of the linear data, a lognormal distribution is a somewhat better fit than a Gaussian distribution for lower 1/3-octave bands, while the reverse is true at higher frequencies. For the distribution of the overall linear levels, a Gaussian distribution is generally the most representative. As a simple description of the response variability, it is sufficient for this series of measurements to assume that the acoustically induced airborne cabin noise is best described by a Gaussian distribution with a normalised standard deviation between 0.09 and 0.145. There is generally considerable variability in the roller-induced noise, with individual 1/3-octave levels varying by typically 15 dB or so and with the normalised standard deviation being in the range 0.2-0.35 or more. These levels are strongly affected by wheel rim and tyre constructions. For vehicles with nominally identical wheel rims and tyres, the normalised standard deviation for 1/3-octave levels in the frequency range 40-600 Hz is 0.2 or so. The distribution of the linear roller-induced noise level in each 1/3-octave frequency band is well described by a lognormal distribution as is the overall level. As a simple description of the response variability, it is sufficient for this series of measurements to assume that the roller-induced road noise is best described by a lognormal distribution with a normalised standard deviation of 0.2 or so, but that this can be significantly affected by the tyre and rim type, especially at lower frequencies.

  17. A simplified physical model for assessing solar radiation over Brazil using GOES 8 visible imagery

    NASA Astrophysics Data System (ADS)

    Ceballos, Juan Carlos; Bottino, Marcus Jorge; de Souza, Jaidete Monteiro

    2004-01-01

    Solar radiation assessment by satellite is constrained by physical limitations of imagery and by the accuracy of instantaneous local atmospheric parameters, suggesting that one should use simplified but physically consistent models for operational work. Such a model is presented for use with GOES 8 imagery applied to atmospheres with low aerosol optical depth. Fundamental satellite-derived parameters are reflectance and cloud cover. A classification method applied to a set of images shows that reflectance, usually defined as upper-threshold Rmax in algorithms assessing cloud cover, would amount ˜0.465, corresponding to the transition between a cumuliform and a stratiform cloud field. Ozone absorption is limited to the stratosphere. The model considers two spectral broadband intervals for tropospheric radiative transfer: ultraviolet and visible intervals are essentially nonabsorbing and can be processed as a single interval, while near-infrared intervals have negligible atmospheric scattering and very low cloud transmittance. Typical values of CO2 and O3 content and of precipitable water are considered. A comparison of daily values of modeled mean irradiance with data of three sites (in rural, urban industrial, and urban coastal environments), September-October 2002, exhibits a bias of +5 W m-2 and a standard deviation of ˜15 W m-2 (0.4 and 1.3 MJ m-2 for daily irradiation). A comparison with monthly means from about 80 automatic weather stations (covering a large area throughout the Brazilian territory) still shows a bias generally within ±10 W m-2 and a low standard deviation (<20 W m-2), but the bias has a trend in September-December 2002, suggesting an annual cycle of local Rmax values. Systematic (mean) errors in partial cloud cover and in nearly clear-sky situations may be enhanced using regional values for atmospheric and surface parameters, such as precipitable water, Rmax, and ground reflectance. The larger errors are observed in situations of high aerosol load (especially in regions with industrial activity or forest or agricultural fires). The last case is evident when sites in the Amazonian region or São Paulo city are selected. When considering daily values averaged within 2.5° × 2.5° cells, the standard error is lower than 20 W m-2; present results suggest an annual cycle of mean bias ranging from +10 to -10 W m-2, with an amplitude of ˜10 W m-2. These values are close to the proposed requirements of 10 W m-2 for the mean deviation and 25 W m-2 for the standard deviation. It is expected that the introduction of a reference grid containing mean values of parameters within a cell could induce a decrease in the standard deviation of mean errors and the correction of their annual cycle. A model adaptation for assessing the effect of high aerosol loads is needed in order to extend improvements to the whole Brazilian area.

  18. Derivative spectrophotometry for the determination of faropenem in the presence of degradation products: an application for kinetic studies.

    PubMed

    Cielecka-Piontek, Judyta

    2013-07-01

    A simple and selective derivative spectrophotometric method was developed for the quantitative determination of faropenem in pure form and in pharmaceutical dosage. The method is based on the zero-crossing effect of first-derivative spectrophotometry (λ = 324 nm), which eliminates the overlapping effect caused by the excipients present in the pharmaceutical preparation, as well as degradation products, formed during hydrolysis, oxidation, photolysis, and thermolysis. The method was linear in the concentration range 2.5-300 μg/mL (r = 0.9989) at λ = 341 nm; the limits of detection and quantitation were 0.16 and 0.46 μg/mL, respectively. The method had good precision (relative standard deviation from 0.68 to 2.13%). Recovery of faropenem ranged from 97.9 to 101.3%. The first-order rate constants of the degradation of faropenem in pure form and in pharmaceutical dosage were determined by using first-derivative spectrophotometry. A statistical comparison of the validation results and the observed rate constants for faropenem degradation with these obtained with the high-performance liquid chromatography method demonstrated that both were compatible.

  19. Introducing the Mean Absolute Deviation "Effect" Size

    ERIC Educational Resources Information Center

    Gorard, Stephen

    2015-01-01

    This paper revisits the use of effect sizes in the analysis of experimental and similar results, and reminds readers of the relative advantages of the mean absolute deviation as a measure of variation, as opposed to the more complex standard deviation. The mean absolute deviation is easier to use and understand, and more tolerant of extreme…

  20. Standard deviations of composition measurements in atom probe analyses-Part II: 3D atom probe.

    PubMed

    Danoix, F; Grancher, G; Bostel, A; Blavette, D

    2007-09-01

    In a companion paper [F. Danoix, G. Grancher, A. Bostel, D. Blavette, Surf. Interface Anal. this issue (previous paper).], the derivation of variances of the estimates of measured composition, and the underlying hypotheses, have been revisited in the the case of conventional one dimensional (1D) atom probes. In this second paper, we will concentrate on the analytical derivation of the variance when the estimate of composition is obtained from a 3D atom probe. As will be discussed, when the position information is available, compositions can be derived either from constant number of atoms, or from constant volume, blocks. The analytical treatment in the first case is identical to the one developed for conventional 1D instruments, and will not be discussed further in this paper. Conversely, in the second case, the analytical treatment is different, as well as the formula of the variance. In particular, it will be shown that the detection efficiency plays an important role in the determination of the variance.

  1. Selection of vegetation indices for mapping the sugarcane condition around the oil and gas field of North West Java Basin, Indonesia

    NASA Astrophysics Data System (ADS)

    Muji Susantoro, Tri; Wikantika, Ketut; Saepuloh, Asep; Handoyo Harsolumakso, Agus

    2018-05-01

    Selection of vegetation indices in plant mapping is needed to provide the best information of plant conditions. The methods used in this research are the standard deviation and the linear regression. This research tried to determine the vegetation indices used for mapping the sugarcane conditions around oil and gas fields. The data used in this study is Landsat 8 OLI/TIRS. The standard deviation analysis on the 23 vegetation indices with 27 samples has resulted in the six highest standard deviations of vegetation indices, termed as GRVI, SR, NLI, SIPI, GEMI and LAI. The standard deviation values are 0.47; 0.43; 0.30; 0.17; 0.16 and 0.13. Regression correlation analysis on the 23 vegetation indices with 280 samples has resulted in the six vegetation indices, termed as NDVI, ENDVI, GDVI, VARI, LAI and SIPI. This was performed based on regression correlation with the lowest value R2 than 0,8. The combined analysis of the standard deviation and the regression correlation has obtained the five vegetation indices, termed as NDVI, ENDVI, GDVI, LAI and SIPI. The results of the analysis of both methods show that a combination of two methods needs to be done to produce a good analysis of sugarcane conditions. It has been clarified through field surveys and showed good results for the prediction of microseepages.

  2. Spectroscopic study of the reaction mechanism of buspirone interaction with iodine and tetracyanoethylene reagents and its applications.

    PubMed

    Zayed, M A; El-Habeeb, Abeer A

    2009-06-01

    The reactions between the drug buspirone (busp) in its base form and iodine amphoteric reagent (n-donor and/or sigma-acceptor) and with tetracyanoethylene as a pi-acceptor reagent (TCNE) have been studied spectrophotometrically at different reactant concentrations, time intervals, temperatures, and with different solvents and wavelengths, with the aim of selecting the conditions that give the most suitable molar extinction coefficients. This study aims chiefly to throw light on the nature of these reactions and to select the most proper conditions for spectrophotometric application of these reagents to determine this biologically active drug used in treating different diseases. The reaction mechanism involves the formation of busp-I(2) outer and inner sphere complexes. The separated busp-I(2) solid product obtained was investigated using elemental analyses, FT-IR, thermal analyses (TA) and electron ionization mass spectrometry (EI-MS) and was found to be biologically active. The reaction mechanism of busp-TCNE involves the formation of a charge transfer (CT) complex. The analytical parameters of the proposed spectrophotometric procedures were calculated. These procedures were applied in the analysis of busp in its formulations as a drug used to treat psychiatric illnesses. The values of the Sandell sensitivity, standard deviation (SD), relative standard deviation (RSD) and recovery percentage show the high sensitivity of these procedures. This study also presents a promising new busp-I(2) drug derivative that can be used more efficiently for the same purposes as its parent. It gives a clear idea about the possible metabolites and metabolic pathways of busp and its derivative that may occur in vivo. Copyright 2009 John Wiley & Sons, Ltd.

  3. An Assessment of State-of-the-Art Mean Sea Surface and Geoid Models of the Arctic Ocean: Implications for Sea Ice Freeboard Retrieval

    NASA Astrophysics Data System (ADS)

    Skourup, Henriette; Farrell, Sinéad Louise; Hendricks, Stefan; Ricker, Robert; Armitage, Thomas W. K.; Ridout, Andy; Andersen, Ole Baltazar; Haas, Christian; Baker, Steven

    2017-11-01

    State-of-the-art Arctic Ocean mean sea surface (MSS) models and global geoid models (GGMs) are used to support sea ice freeboard estimation from satellite altimeters, as well as in oceanographic studies such as mapping sea level anomalies and mean dynamic ocean topography. However, errors in a given model in the high-frequency domain, primarily due to unresolved gravity features, can result in errors in the estimated along-track freeboard. These errors are exacerbated in areas with a sparse lead distribution in consolidated ice pack conditions. Additionally model errors can impact ocean geostrophic currents, derived from satellite altimeter data, while remaining biases in these models may impact longer-term, multisensor oceanographic time series of sea level change in the Arctic. This study focuses on an assessment of five state-of-the-art Arctic MSS models (UCL13/04 and DTU15/13/10) and a commonly used GGM (EGM2008). We describe errors due to unresolved gravity features, intersatellite biases, and remaining satellite orbit errors, and their impact on the derivation of sea ice freeboard. The latest MSS models, incorporating CryoSat-2 sea surface height measurements, show improved definition of gravity features, such as the Gakkel Ridge. The standard deviation between models ranges 0.03-0.25 m. The impact of remaining MSS/GGM errors on freeboard retrieval can reach several decimeters in parts of the Arctic. While the maximum observed freeboard difference found in the central Arctic was 0.59 m (UCL13 MSS minus EGM2008 GGM), the standard deviation in freeboard differences is 0.03-0.06 m.

  4. The impact of inter-fraction dose variations on biological equivalent dose (BED): the concept of equivalent constant dose.

    PubMed

    Zavgorodni, S

    2004-12-07

    Inter-fraction dose fluctuations, which appear as a result of setup errors, organ motion and treatment machine output variations, may influence the radiobiological effect of the treatment even when the total delivered physical dose remains constant. The effect of these inter-fraction dose fluctuations on the biological effective dose (BED) has been investigated. Analytical expressions for the BED accounting for the dose fluctuations have been derived. The concept of biological effective constant dose (BECD) has been introduced. The equivalent constant dose (ECD), representing the constant physical dose that provides the same cell survival fraction as the fluctuating dose, has also been introduced. The dose fluctuations with Gaussian as well as exponential probability density functions were investigated. The values of BECD and ECD calculated analytically were compared with those derived from Monte Carlo modelling. The agreement between Monte Carlo modelled and analytical values was excellent (within 1%) for a range of dose standard deviations (0-100% of the dose) and the number of fractions (2 to 37) used in the comparison. The ECDs have also been calculated for conventional radiotherapy fields. The analytical expression for the BECD shows that BECD increases linearly with the variance of the dose. The effect is relatively small, and in the flat regions of the field it results in less than 1% increase of ECD. In the penumbra region of the 6 MV single radiotherapy beam the ECD exceeded the physical dose by up to 35%, when the standard deviation of combined patient setup/organ motion uncertainty was 5 mm. Equivalently, the ECD field was approximately 2 mm wider than the physical dose field. The difference between ECD and the physical dose is greater for normal tissues than for tumours.

  5. Residual standard deviation: Validation of a new measure of dual-task cost in below-knee prosthesis users.

    PubMed

    Howard, Charla L; Wallace, Chris; Abbas, James; Stokic, Dobrivoje S

    2017-01-01

    We developed and evaluated properties of a new measure of variability in stride length and cadence, termed residual standard deviation (RSD). To calculate RSD, stride length and cadence are regressed against velocity to derive the best fit line from which the variability (SD) of the distance between the actual and predicted data points is calculated. We examined construct, concurrent, and discriminative validity of RSD using dual-task paradigm in 14 below-knee prosthesis users and 13 age- and education-matched controls. Subjects walked first over an electronic walkway while performing separately a serial subtraction and backwards spelling task, and then at self-selected slow, normal, and fast speeds used to derive the best fit line for stride length and cadence against velocity. Construct validity was demonstrated by significantly greater increase in RSD during dual-task gait in prosthesis users than controls (group-by-condition interaction, stride length p=0.0006, cadence p=0.009). Concurrent validity was established against coefficient of variation (CV) by moderate-to-high correlations (r=0.50-0.87) between dual-task cost RSD and dual-task cost CV for both stride length and cadence in prosthesis users and controls. Discriminative validity was documented by the ability of dual-task cost calculated from RSD to effectively differentiate prosthesis users from controls (area under the receiver operating characteristic curve, stride length 0.863, p=0.001, cadence 0.808, p=0.007), which was better than the ability of dual-task cost CV (0.692, 0.648, respectively, not significant). These results validate RSD as a new measure of variability in below-knee prosthesis users. Future studies should include larger cohorts and other populations to ascertain its generalizability. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. OPACITY BROADENING OF {sup 13}CO LINEWIDTHS AND ITS EFFECT ON THE VARIANCE-SONIC MACH NUMBER RELATION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Correia, C.; De Medeiros, J. R.; Burkhart, B.

    2014-04-10

    We study how the estimation of the sonic Mach number (M{sub s} ) from {sup 13}CO linewidths relates to the actual three-dimensional sonic Mach number. For this purpose we analyze MHD simulations that include post-processing to take radiative transfer effects into account. As expected, we find very good agreement between the linewidth estimated sonic Mach number and the actual sonic Mach number of the simulations for optically thin tracers. However, we find that opacity broadening causes M{sub s} to be overestimated by a factor of ≈1.16-1.3 when calculated from optically thick {sup 13}CO lines. We also find that there ismore » a dependence on the magnetic field: super-Alfvénic turbulence shows increased line broadening compared with sub-Alfvénic turbulence for all values of optical depth for supersonic turbulence. Our results have implications for the observationally derived sonic Mach number-density standard deviation (σ{sub ρ/(ρ)}) relationship, σ{sub ρ/〈ρ〉}{sup 2}=b{sup 2}M{sub s}{sup 2}, and the related column density standard deviation (σ {sub N/(N)}) sonic Mach number relationship. In particular, we find that the parameter b, as an indicator of solenoidal versus compressive driving, will be underestimated as a result of opacity broadening. We compare the σ {sub N/(N)}-M{sub s} relation derived from synthetic dust extinction maps and {sup 13}CO linewidths with recent observational studies and find that solenoidally driven MHD turbulence simulations have values of σ {sub N/(N)}which are lower than real molecular clouds. This may be due to the influence of self-gravity which should be included in simulations of molecular cloud dynamics.« less

  7. The MODIS Aerosol Algorithm, Products and Validation

    NASA Technical Reports Server (NTRS)

    Remer, L. A.; Kaufman, Y. J.; Tanre, D.; Mattoo, S.; Chu, D. A.; Martins, J. V.; Li, R.-R.; Ichoku, C.; Levy, R. C.; Kleidman, R. G.

    2003-01-01

    The MODerate resolution Imaging Spectroradiometer (MODIS) aboard both NASA's Terra and Aqua satellites is making near global daily observations of the earth in a wide spectral range. These measurements are used to derive spectral aerosol optical thickness and aerosol size parameters over both land and ocean. The aerosol products available over land include aerosol optical thickness at three visible wavelengths, a measure of the fraction of aerosol optical thickness attributed to the fine mode and several derived parameters including reflected spectral solar flux at top of atmosphere. Over ocean, the aerosol optical thickness is provided in seven wavelengths from 0.47 microns to 2.13 microns. In addition, quantitative aerosol size information includes effective radius of the aerosol and quantitative fraction of optical thickness attributed to the fine mode. Spectral aerosol flux, mass concentration and number of cloud condensation nuclei round out the list of available aerosol products over the ocean. The spectral optical thickness and effective radius of the aerosol over the ocean are validated by comparison with two years of AERONET data gleaned from 133 AERONET stations. 8000 MODIS aerosol retrievals colocated with AERONET measurements confirm that one-standard deviation of MODIS optical thickness retrievals fall within the predicted uncertainty of delta tauapproximately equal to plus or minus 0.03 plus or minus 0.05 tau over ocean and delta tay equal to plus or minus 0.05 plus or minus 0.15 tau over land. 271 MODIS aerosol retrievals co-located with AERONET inversions at island and coastal sites suggest that one-standard deviation of MODIS effective radius retrievals falls within delta r_eff approximately equal to 0.11 microns. The accuracy of the MODIS retrievals suggests that the product can be used to help narrow the uncertainties associated with aerosol radiative forcing of global climate.

  8. Effects of Neighborhood Resources on Aggressive and Delinquent Behaviors Among Urban Youths

    PubMed Central

    Molnar, Beth E.; Cerda, Magdalena; Roberts, Andrea L.; Buka, Stephen L.

    2008-01-01

    Objectives. We sought to identify neighborhood-level resources associated with lower levels of aggression and delinquency among youths aged 9–15 years at baseline after accounting for risk factors and other types of resources. Methods. Data were derived from the Project on Human Development in Chicago Neighborhoods, which focused on 2226 ethnically diverse, urban youths, their caregivers, and the 80 neighborhoods in which they resided at baseline. Results. Living in a neighborhood with a higher concentration of organizations or services serving young people and adults was associated with lower levels of aggression (odds ratio [OR]=0.9; 95% confidence interval [CI]=0.8, 1.0); living in such a neighborhood also moderated family, peer, and mentor resources. For example, the presence of well-behaved peers was associated with lower levels of aggression among youths living in neighborhoods where the concentration of organizations and services was at least 1 standard deviation above the mean; the association was less strong among youths living in neighborhoods with organizations and services 1 standard deviation below the mean or less. Conclusions. Certain family, peer, and mentoring resources may confer benefits only in the presence of neighborhood resources. Increasing neighborhood resources should be considered in interventions designed to reduce urban youths’ involvement in violence. PMID:17901441

  9. Community covariates of malnutrition based mortality among older adults.

    PubMed

    Lee, Matthew R; Berthelot, Emily R

    2010-05-01

    The purpose of this study was to identify community level covariates of malnutrition-based mortality among older adults. A community level framework was delineated which explains rates of malnutrition-related mortality among older adults as a function of community levels of socioeconomic disadvantage, disability, and social isolation among members of this group. County level data on malnutrition mortality of people 65 years of age and older for the period 2000-2003 were drawn from the CDC WONDER system databases. County level measures of older adult socioeconomic disadvantage, disability, and social isolation were derived from the 2000 US Census of Population and Housing. Negative binomial regression models adjusting for the size of the population at risk, racial composition, urbanism, and region were estimated to assess the relationships among these indicators. Results from negative binomial regression analysis yielded the following: a standard deviation increase in socioeconomic/physical disadvantage was associated with a 12% increase in the rate of malnutrition mortality among older adults (p < 0.001), whereas a standard deviation increase in social isolation was associated with a 5% increase in malnutrition mortality among older adults (p < 0.05). Community patterns of malnutrition based mortality among older adults are partly a function of levels of socioeconomic and physical disadvantage and social isolation among older adults. 2010 Elsevier Inc. All rights reserved.

  10. A HELIOSEISMIC SURVEY OF NEAR-SURFACE FLOWS AROUND ACTIVE REGIONS AND THEIR ASSOCIATION WITH FLARES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Braun, D. C., E-mail: dbraun@cora.nwra.com

    We use helioseismic holography to study the association of shallow flows with solar flare activity in about 250 large sunspot groups observed between 2010 and 2014 with the Helioseismic and Magnetic Imager on the Solar Dynamics Observatory. Four basic flow parameters: horizontal speed, horizontal component of divergence, vertical component of vorticity, and a vertical kinetic helicity proxy, are mapped for each active region (AR) during its passage across the solar disk. Flow indices are derived representing the mean and standard deviation of these parameters over magnetic masks and compared with contemporary measures of flare X-ray flux. A correlation exists formore » several of the flow indices, especially those based on the speed and the standard deviation of all flow parameters. However, their correlation with X-ray flux is similar to that observed with the mean unsigned magnetic flux density over the same masks. The temporal variation of the flow indices are studied, and a superposed epoch analysis with respect to the occurrence to 70 M and X-class flares is made. While flows evolve with the passage of the ARs across the disk, no discernible precursors or other temporal changes specifically associated with flares are detected.« less

  11. Faraday dispersion functions of galaxies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ideguchi, Shinsuke; Tashiro, Yuichi; Takahashi, Keitaro

    2014-09-01

    The Faraday dispersion function (FDF), which can be derived from an observed polarization spectrum by Faraday rotation measure synthesis, is a profile of polarized emissions as a function of Faraday depth. We study intrinsic FDFs along sight lines through face-on Milky Way like galaxies by means of a sophisticated galactic model incorporating three-dimensional MHD turbulence, and investigate how much information the FDF intrinsically contains. Since the FDF reflects distributions of thermal and cosmic-ray electrons as well as magnetic fields, it has been expected that the FDF could be a new probe to examine internal structures of galaxies. We, however, findmore » that an intrinsic FDF along a sight line through a galaxy is very complicated, depending significantly on actual configurations of turbulence. We perform 800 realizations of turbulence and find no universal shape of the FDF even if we fix the global parameters of the model. We calculate the probability distribution functions of the standard deviation, skewness, and kurtosis of FDFs and compare them for models with different global parameters. Our models predict that the presence of vertical magnetic fields and the large-scale height of cosmic-ray electrons tend to make the standard deviation relatively large. In contrast, the differences in skewness and kurtosis are relatively less significant.« less

  12. Statistical analysis of solid waste composition data: Arithmetic mean, standard deviation and correlation coefficients.

    PubMed

    Edjabou, Maklawe Essonanawe; Martín-Fernández, Josep Antoni; Scheutz, Charlotte; Astrup, Thomas Fruergaard

    2017-11-01

    Data for fractional solid waste composition provide relative magnitudes of individual waste fractions, the percentages of which always sum to 100, thereby connecting them intrinsically. Due to this sum constraint, waste composition data represent closed data, and their interpretation and analysis require statistical methods, other than classical statistics that are suitable only for non-constrained data such as absolute values. However, the closed characteristics of waste composition data are often ignored when analysed. The results of this study showed, for example, that unavoidable animal-derived food waste amounted to 2.21±3.12% with a confidence interval of (-4.03; 8.45), which highlights the problem of the biased negative proportions. A Pearson's correlation test, applied to waste fraction generation (kg mass), indicated a positive correlation between avoidable vegetable food waste and plastic packaging. However, correlation tests applied to waste fraction compositions (percentage values) showed a negative association in this regard, thus demonstrating that statistical analyses applied to compositional waste fraction data, without addressing the closed characteristics of these data, have the potential to generate spurious or misleading results. Therefore, ¨compositional data should be transformed adequately prior to any statistical analysis, such as computing mean, standard deviation and correlation coefficients. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. 1H-NMR and Hyperpolarized 13C-NMR Assays of Pyruvate-Lactate Exhange: a comparative study

    PubMed Central

    Orton, Matthew R.; Tardif, Nicolas; Parkes, Harold G.; Robinson, Simon P.; Leach, Martin O.; Chung, Yuen-Li; Eykyn, Thomas R.

    2015-01-01

    Pyruvate-lactate exchange is mediated by the enzyme lactate dehydrogenase (LDH) and is central to the altered energy metabolism in cancer cells. Measurement of exchange kinetics using hyperpolarized 13C NMR has provided a biomarker of response to novel therapeutics. In this study we investigated an alternative in vitro 1H assay, using [3-13C]pyruvate, and compared the measured kinetics with a hyperpolarized 13C-NMR assay, using [1-13C]pyruvate, under the same conditions in human colorectal carcinoma SW1222 cells. The apparent forward reaction rate constants (kPL) derived from the two assays showed no significant difference, and both assays had similar reproducibility (kPL = 0.506 ± 0.054 and kPL = 0.441 ± 0.090 nmol/s/106 cells, (mean ± standard deviation, n = 3); 1H, 13C assays respectively). The apparent backward reaction rate constant (kLP) could only be measured with good reproducibility using the 1H-NMR assay (kLP = 0.376 ± 0.091 nmol/s/106 cells, (mean ± standard deviation, n = 3)). The 1H-NMR assay has adequate sensitivity to measure real-time pyruvate-lactate exchange kinetics in vitro, offering a complementary and accessible assay of apparent LDH activity. PMID:23712817

  14. Standard deviation of the mean and other time series properties of voltages measured with a digital lock-in amplifier

    NASA Astrophysics Data System (ADS)

    Witt, Thomas J.; Fletcher, N. E.

    2010-10-01

    We investigate some statistical properties of ac voltages from a white noise source measured with a digital lock-in amplifier equipped with finite impulse response output filters which introduce correlations between successive voltage values. The main goal of this work is to propose simple solutions to account for correlations when calculating the standard deviation of the mean (SDM) for a sequence of measurement data acquired using such an instrument. The problem is treated by time series analysis based on a moving average model of the filtering process. Theoretical expressions are derived for the power spectral density (PSD), the autocorrelation function, the equivalent noise bandwidth and the Allan variance; all are related to the SDM. At most three parameters suffice to specify any of the above quantities: the filter time constant, the time between successive measurements (both set by the lock-in operator) and the PSD of the white noise input, h0. Our white noise source is a resistor so that the PSD is easily calculated; there are no free parameters. Theoretical expressions are checked against their respective sample estimates and, with the exception of two of the bandwidth estimates, agreement to within 11% or better is found.

  15. WE-AB-303-05: Breathing Motion of Liver Segments From Fiducial Tracking During Robotic Radiosurgery and Comparison with 4D-CT-Derived Fiducial Motion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sutherland, J; Pantarotto, J; Nair, V

    Purpose: To quantify respiratory-induced motion of liver segments using the positions of implanted fiducials during robotic radiosurgery. This study also compared fiducial motion derived from four-dimensional computed tomography (4D-CT) maximum intensity projections (MIP) with motion derived from imaging during treatment. Methods: Forty-two consecutive liver patients treated with liver ablative radiotherapy were accrued to an ethics approved retrospective study. The liver segment in which each fiducial resided was identified. Fiducial positions throughout each treatment fraction were determined using orthogonal kilovoltage images. Any data due to patient repositioning or motion was removed. Mean fiducial positions were calculated. Fiducial positions beyond two standardmore » deviations of the mean were discarded and remaining positions were fit to a line segment using least squares minimization (LSM). For eight patients, fiducial motion was derived from 4D-CT MIPs by calculating the CT number weighted mean position of the fiducial on each slice and fitting a line segment to these points using LSM. Treatment derived fiducial trajectories were corrected for patient rotation and compared to MIP derived trajectories. Results: The mean total magnitude of fiducial motion across all liver segments in left-right, anteroposterior, and superoinferior (SI) directions were 3.0 ± 0.2 mm, 9.3 ± 0.4 mm, and 20.5 ± 0.5 mm, respectively. Differences in per-segment mean fiducial motion were found with SI motion ranging from 12.6 ± 0.8 mm to 22.6 ± 0.9 mm for segments 3 and 8, respectively. Large, varied differences between treatment and MIP derived motion at simulation were found with the mean difference for SI motion being 2.6 mm (10.8 mm standard deviation). Conclusion: The magnitude of liver fiducial motion was found to differ by liver segment. MIP derived liver fiducial motion differed from motion observed during treatment, implying that 4D-CTs may not accurately capture the range of liver motion across fractions and during treatment. Author V. Nair was funded by the Cushing estate for a SABR clinical research fellowship.« less

  16. Reproducibility of a Standardized Actigraphy Scoring Algorithm for Sleep in a US Hispanic/Latino Population

    PubMed Central

    Patel, Sanjay R.; Weng, Jia; Rueschman, Michael; Dudley, Katherine A.; Loredo, Jose S.; Mossavar-Rahmani, Yasmin; Ramirez, Maricelle; Ramos, Alberto R.; Reid, Kathryn; Seiger, Ashley N.; Sotres-Alvarez, Daniela; Zee, Phyllis C.; Wang, Rui

    2015-01-01

    Study Objectives: While actigraphy is considered objective, the process of setting rest intervals to calculate sleep variables is subjective. We sought to evaluate the reproducibility of actigraphy-derived measures of sleep using a standardized algorithm for setting rest intervals. Design: Observational study. Setting: Community-based. Participants: A random sample of 50 adults aged 18–64 years free of severe sleep apnea participating in the Sueño sleep ancillary study to the Hispanic Community Health Study/Study of Latinos. Interventions: N/A. Measurements and Results: Participants underwent 7 days of continuous wrist actigraphy and completed daily sleep diaries. Studies were scored twice by each of two scorers. Rest intervals were set using a standardized hierarchical approach based on event marker, diary, light, and activity data. Sleep/wake status was then determined for each 30-sec epoch using a validated algorithm, and this was used to generate 11 variables: mean nightly sleep duration, nap duration, 24-h sleep duration, sleep latency, sleep maintenance efficiency, sleep fragmentation index, sleep onset time, sleep offset time, sleep midpoint time, standard deviation of sleep duration, and standard deviation of sleep midpoint. Intra-scorer intraclass correlation coefficients (ICCs) were high, ranging from 0.911 to 0.995 across all 11 variables. Similarly, inter-scorer ICCs were high, also ranging from 0.911 to 0.995, and mean inter-scorer differences were small. Bland-Altman plots did not reveal any systematic disagreement in scoring. Conclusions: With use of a standardized algorithm to set rest intervals, scoring of actigraphy for the purpose of generating a wide array of sleep variables is highly reproducible. Citation: Patel SR, Weng J, Rueschman M, Dudley KA, Loredo JS, Mossavar-Rahmani Y, Ramirez M, Ramos AR, Reid K, Seiger AN, Sotres-Alvarez D, Zee PC, Wang R. Reproducibility of a standardized actigraphy scoring algorithm for sleep in a US Hispanic/Latino population. SLEEP 2015;38(9):1497–1503. PMID:25845697

  17. Robust Confidence Interval for a Ratio of Standard Deviations

    ERIC Educational Resources Information Center

    Bonett, Douglas G.

    2006-01-01

    Comparing variability of test scores across alternate forms, test conditions, or subpopulations is a fundamental problem in psychometrics. A confidence interval for a ratio of standard deviations is proposed that performs as well as the classic method with normal distributions and performs dramatically better with nonnormal distributions. A simple…

  18. Standard Deviation for Small Samples

    ERIC Educational Resources Information Center

    Joarder, Anwar H.; Latif, Raja M.

    2006-01-01

    Neater representations for variance are given for small sample sizes, especially for 3 and 4. With these representations, variance can be calculated without a calculator if sample sizes are small and observations are integers, and an upper bound for the standard deviation is immediate. Accessible proofs of lower and upper bounds are presented for…

  19. Estimating maize water stress by standard deviation of canopy temperature in thermal imagery

    USDA-ARS?s Scientific Manuscript database

    A new crop water stress index using standard deviation of canopy temperature as an input was developed to monitor crop water status. In this study, thermal imagery was taken from maize under various levels of deficit irrigation treatments in different crop growing stages. The Expectation-Maximizatio...

  20. Profound Effect of Profiling Platform and Normalization Strategy on Detection of Differentially Expressed MicroRNAs – A Comparative Study

    PubMed Central

    Meyer, Swanhild U.; Kaiser, Sebastian; Wagner, Carola; Thirion, Christian; Pfaffl, Michael W.

    2012-01-01

    Background Adequate normalization minimizes the effects of systematic technical variations and is a prerequisite for getting meaningful biological changes. However, there is inconsistency about miRNA normalization performances and recommendations. Thus, we investigated the impact of seven different normalization methods (reference gene index, global geometric mean, quantile, invariant selection, loess, loessM, and generalized procrustes analysis) on intra- and inter-platform performance of two distinct and commonly used miRNA profiling platforms. Methodology/Principal Findings We included data from miRNA profiling analyses derived from a hybridization-based platform (Agilent Technologies) and an RT-qPCR platform (Applied Biosystems). Furthermore, we validated a subset of miRNAs by individual RT-qPCR assays. Our analyses incorporated data from the effect of differentiation and tumor necrosis factor alpha treatment on primary human skeletal muscle cells and a murine skeletal muscle cell line. Distinct normalization methods differed in their impact on (i) standard deviations, (ii) the area under the receiver operating characteristic (ROC) curve, (iii) the similarity of differential expression. Loess, loessM, and quantile analysis were most effective in minimizing standard deviations on the Agilent and TLDA platform. Moreover, loess, loessM, invariant selection and generalized procrustes analysis increased the area under the ROC curve, a measure for the statistical performance of a test. The Jaccard index revealed that inter-platform concordance of differential expression tended to be increased by loess, loessM, quantile, and GPA normalization of AGL and TLDA data as well as RGI normalization of TLDA data. Conclusions/Significance We recommend the application of loess, or loessM, and GPA normalization for miRNA Agilent arrays and qPCR cards as these normalization approaches showed to (i) effectively reduce standard deviations, (ii) increase sensitivity and accuracy of differential miRNA expression detection as well as (iii) increase inter-platform concordance. Results showed the successful adoption of loessM and generalized procrustes analysis to one-color miRNA profiling experiments. PMID:22723911

  1. The angulation of the septal structures impacts ventricular imbalance in atrioventricular septal defects with a common atrioventricular junction.

    PubMed

    Ahmad, Zaheer; Lim, Zek; Roman, Kevin; Haw, Marcus; Anderson, Robert H; Vettukattil, Joseph

    2016-02-01

    Multiplanar re-formatting of full-volume three-dimensional echocardiography data sets offers new insights into the morphology of atrioventricular septal defects. We hypothesised that distortion of the alignment between the atrial and ventricular septums results in imbalanced venous return to the ventricles, with consequent proportional ventricular hypoplasia. A single observer evaluated 31 patients, with a mean age of 52.09 months, standard deviation of 55, and with a range from 2 to 264 months, with atrioventricular septal defects, of whom 17 were boys. Ventricular imbalance, observed in nine patients, was determined by two-dimensional assessment, and confirmed at surgical inspection in selected cases when a univentricular strategy was undertaken. Offline analysis using multiplanar re-formatting was performed. A line was drawn though the length of the ventricular septum and a second line along the plane of the atrial septum, taking the angle between these two lines as the atrioventricular septal angle. We compared the angle between 22 patients with adequately sized ventricles, and those with ventricular imbalance undergoing univentricular repair. In the 22 patients undergoing biventricular repair, the septal angle was 0 in 14 patients; the other eight patients having angles ranging from 1 to 36, with a mean angle of 7.4°, and standard deviation of 11.1°.The mean angle in the nine patients with ventricle imbalance was 28.6°, with a standard deviation of 3.04°, and with a range from 26 to 35°. Of those undergoing univentricular repair, two patients died, with angles of 26 and 30°, respectively. The atrioventricular septal angle derived via multiplanar formatting gives important information regarding the degree of ventricular hypoplasia and imbalance. When this angle is above 25°, patients are likely to have ventricular imbalance requiring univentricular repair.

  2. Age estimates for the late quaternary high sea-stands

    NASA Astrophysics Data System (ADS)

    Smart, Peter L.; Richards, David A.

    A database of more than 300 published alpha-counted uranium-series ages has been compiled for coral reef terraces formed by Late Pleistocene high sea-stands. The database was screened to eliminate unreliable age estimates ( {230Th }/{232Th } < 20, calcite > 5%) and those without quoted without quoted errors, and a distributed error frequency curve was produced. This curve can be considered as a finite mixture model comprising k component normal distributions each with a weighting α. By using an expectation maximising algorithm, the mean and standard deviation of the component distributions, each corresponding to a high sea level event, were estimated. Eight high sea-stands with mean and standard deviations of 129.0 ± 33.0, 123.0 ± 13.0, 102.5 ± 2.0, 81.5 ± 5.0, 61.5 ± 6.0, 50.0 ± 1.0, 40.5 ± 5.0 and 33.0 ± 2.5 ka were resolved. The standard deviations are generally larger than the values quoted for individual age estimates. Whilst this may be due to diagenetic effects, especially for the older corals, it is argued that in many cases geological evidence clearly indicates that the high stands are multiple events, often not resolvable at sites with low rates of uplift. The uranium-series dated coral-reef terrace chronology shows good agreement with independent chronologies derived for Antarctic ice cores, although the resolution for the latter is better. Agreement with orbitally-tuned deep-sea core records is also good, but it is argued that Isotope Stage 5e is not a single event, as recorded in the cores, but a multiple event spanning some 12 ka. The much earlier age for Isotope Stage 5e given by Winograd et al. (1988) is not supported by the coral reef data, but further mass-spectrometric uranium-series dating is needed to permit better chronological resolution.

  3. Constraints on deviations from ΛCDM within Horndeski gravity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bellini, Emilio; Cuesta, Antonio J.; Jimenez, Raul

    2016-02-01

    Recent anomalies found in cosmological datasets such as the low multipoles of the Cosmic Microwave Background or the low redshift amplitude and growth of clustering measured by e.g., abundance of galaxy clusters and redshift space distortions in galaxy surveys, have motivated explorations of models beyond standard ΛCDM. Of particular interest are models where general relativity (GR) is modified on large cosmological scales. Here we consider deviations from ΛCDM+GR within the context of Horndeski gravity, which is the most general theory of gravity with second derivatives in the equations of motion. We adopt a parametrization in which the four additional Horndeskimore » functions of time α{sub i}(t) are proportional to the cosmological density of dark energy Ω{sub DE}(t). Constraints on this extended parameter space using a suite of state-of-the art cosmological observations are presented for the first time. Although the theory is able to accommodate the low multipoles of the Cosmic Microwave Background and the low amplitude of fluctuations from redshift space distortions, we find no significant tension with ΛCDM+GR when performing a global fit to recent cosmological data and thus there is no evidence against ΛCDM+GR from an analysis of the value of the Bayesian evidence ratio of the modified gravity models with respect to ΛCDM, despite introducing extra parameters. The posterior distribution of these extra parameters that we derive return strong constraints on any possible deviations from ΛCDM+GR in the context of Horndeski gravity. We illustrate how our results can be applied to a more general frameworks of modified gravity models.« less

  4. Experiments with central-limit properties of spatial samples from locally covariant random fields

    USGS Publications Warehouse

    Barringer, T.H.; Smith, T.E.

    1992-01-01

    When spatial samples are statistically dependent, the classical estimator of sample-mean standard deviation is well known to be inconsistent. For locally dependent samples, however, consistent estimators of sample-mean standard deviation can be constructed. The present paper investigates the sampling properties of one such estimator, designated as the tau estimator of sample-mean standard deviation. In particular, the asymptotic normality properties of standardized sample means based on tau estimators are studied in terms of computer experiments with simulated sample-mean distributions. The effects of both sample size and dependency levels among samples are examined for various value of tau (denoting the size of the spatial kernel for the estimator). The results suggest that even for small degrees of spatial dependency, the tau estimator exhibits significantly stronger normality properties than does the classical estimator of standardized sample means. ?? 1992.

  5. A comparative study of first-derivative spectrophotometry and column high-performance liquid chromatography applied to the determination of repaglinide in tablets and for dissolution testing.

    PubMed

    AlKhalidi, Bashar A; Shtaiwi, Majed; AlKhatib, Hatim S; Mohammad, Mohammad; Bustanji, Yasser

    2008-01-01

    A fast and reliable method for the determination of repaglinide is highly desirable to support formulation screening and quality control. A first-derivative UV spectroscopic method was developed for the determination of repaglinide in tablet dosage form and for dissolution testing. First-derivative UV absorbance was measured at 253 nm. The developed method was validated for linearity, accuracy, precision, limit of detection (LOD), and limit of quantitation (LOQ) in comparison to the U.S. Pharmacopeia (USP) column high-performance liquid chromatographic (HPLC) method. The first-derivative UV spectrophotometric method showed excellent linearity [correlation coefficient (r) = 0.9999] in the concentration range of 1-35 microg/mL and precision (relative standard deviation < 1.5%). The LOD and LOQ were 0.23 and 0.72 microg/mL, respectively, and good recoveries were achieved (98-101.8%). Statistical comparison of results of the first-derivative UV spectrophotometric and the USP HPLC methods using the t-test showed that there was no significant difference between the 2 methods. Additionally, the method was successfully used for the dissolution test of repaglinide and was found to be reliable, simple, fast, and inexpensive.

  6. YALE NATURAL RADIOCARBON MEASUREMENTS. PART VI

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stuiver, M.; Deevey, E.S.

    1961-01-01

    Most of the measurements made since publication of Yale V are included; some measurements, such as a series collected in Greenland, are withneld pending additional information or field work that will make better interpretations possible. In addition to radiocarbon dates of geologic and/or archaeologic interest, recent assays are given of C/sup 14/ in lake waters and other lacustrine materials, now normalized for C/sup 13/ content. The newly accepted convention is followed in expressing normalized C/sup 14/ values as DELTA = delta C/sup 14/ (2 delta C/sup 13/ + 50)STAl + ( delta C/sup 14//1000)! where DELTA is the per milmore » deviation of the C/sup 14/ if the sample from any contemporary standard (whether organic or a carbonate) after correction of sample and/or standard for real age, for the Suess effect, for normal isotopic fractionation, and for deviations of C/sup 14/ content of the age- and pollution- corrected l9th-century wood standard from that of 95% of the NBS oxalic acid standard; delta C/sup 14/ is the measured deviation from 95% of the NBS standard, and delta C/sup 13/ is the deviation from the NBS limestone standard, both in per mil. These assays are variously affected by artificial C/sup 14/ resulting from nuclear tests. (auth)« less

  7. QCD Precision Measurements and Structure Function Extraction at a High Statistics, High Energy Neutrino Scattering Experiment:. NuSOnG

    NASA Astrophysics Data System (ADS)

    Adams, T.; Batra, P.; Bugel, L.; Camilleri, L.; Conrad, J. M.; de Gouvêa, A.; Fisher, P. H.; Formaggio, J. A.; Jenkins, J.; Karagiorgi, G.; Kobilarcik, T. R.; Kopp, S.; Kyle, G.; Loinaz, W. A.; Mason, D. A.; Milner, R.; Moore, R.; Morfín, J. G.; Nakamura, M.; Naples, D.; Nienaber, P.; Olness, F. I.; Owens, J. F.; Pate, S. F.; Pronin, A.; Seligman, W. G.; Shaevitz, M. H.; Schellman, H.; Schienbein, I.; Syphers, M. J.; Tait, T. M. P.; Takeuchi, T.; Tan, C. Y.; van de Water, R. G.; Yamamoto, R. K.; Yu, J. Y.

    We extend the physics case for a new high-energy, ultra-high statistics neutrino scattering experiment, NuSOnG (Neutrino Scattering On Glass) to address a variety of issues including precision QCD measurements, extraction of structure functions, and the derived Parton Distribution Functions (PDF's). This experiment uses a Tevatron-based neutrino beam to obtain a sample of Deep Inelastic Scattering (DIS) events which is over two orders of magnitude larger than past samples. We outline an innovative method for fitting the structure functions using a parametrized energy shift which yields reduced systematic uncertainties. High statistics measurements, in combination with improved systematics, will enable NuSOnG to perform discerning tests of fundamental Standard Model parameters as we search for deviations which may hint of "Beyond the Standard Model" physics.

  8. Inverse correlation between the standard deviation of R-R intervals in supine position and the simplified menopausal index in women with climacteric symptoms.

    PubMed

    Yanagihara, Nobuyuki; Seki, Meikan; Nakano, Masahiro; Hachisuga, Toru; Goto, Yukio

    2014-06-01

    Disturbance of autonomic nervous activity has been thought to play a role in the climacteric symptoms of postmenopausal women. This study was therefore designed to investigate the relationship between autonomic nervous activity and climacteric symptoms in postmenopausal Japanese women. The autonomic nervous activity of 40 Japanese women with climacteric symptoms and 40 Japanese women without climacteric symptoms was measured by power spectral analysis of heart rate variability using a standard hexagonal radar chart. The scores for climacteric symptoms were determined using the simplified menopausal index. Sympathetic excitability and irritability, as well as the standard deviation of mean R-R intervals in supine position, were significantly (P < 0.01, 0.05, and 0.001, respectively) decreased in women with climacteric symptoms. There was a negative correlation between the standard deviation of mean R-R intervals in supine position and the simplified menopausal index score. The lack of control for potential confounding variables was a limitation of this study. In climacteric women, the standard deviation of mean R-R intervals in supine position is negatively correlated with the simplified menopausal index score.

  9. Entanglement transitions induced by large deviations

    NASA Astrophysics Data System (ADS)

    Bhosale, Udaysinh T.

    2017-12-01

    The probability of large deviations of the smallest Schmidt eigenvalue for random pure states of bipartite systems, denoted as A and B , is computed analytically using a Coulomb gas method. It is shown that this probability, for large N , goes as exp[-β N2Φ (ζ ) ] , where the parameter β is the Dyson index of the ensemble, ζ is the large deviation parameter, while the rate function Φ (ζ ) is calculated exactly. Corresponding equilibrium Coulomb charge density is derived for its large deviations. Effects of the large deviations of the extreme (largest and smallest) Schmidt eigenvalues on the bipartite entanglement are studied using the von Neumann entropy. Effect of these deviations is also studied on the entanglement between subsystems 1 and 2, obtained by further partitioning the subsystem A , using the properties of the density matrix's partial transpose ρ12Γ. The density of states of ρ12Γ is found to be close to the Wigner's semicircle law with these large deviations. The entanglement properties are captured very well by a simple random matrix model for the partial transpose. The model predicts the entanglement transition across a critical large deviation parameter ζ . Log negativity is used to quantify the entanglement between subsystems 1 and 2. Analytical formulas for it are derived using the simple model. Numerical simulations are in excellent agreement with the analytical results.

  10. Entanglement transitions induced by large deviations.

    PubMed

    Bhosale, Udaysinh T

    2017-12-01

    The probability of large deviations of the smallest Schmidt eigenvalue for random pure states of bipartite systems, denoted as A and B, is computed analytically using a Coulomb gas method. It is shown that this probability, for large N, goes as exp[-βN^{2}Φ(ζ)], where the parameter β is the Dyson index of the ensemble, ζ is the large deviation parameter, while the rate function Φ(ζ) is calculated exactly. Corresponding equilibrium Coulomb charge density is derived for its large deviations. Effects of the large deviations of the extreme (largest and smallest) Schmidt eigenvalues on the bipartite entanglement are studied using the von Neumann entropy. Effect of these deviations is also studied on the entanglement between subsystems 1 and 2, obtained by further partitioning the subsystem A, using the properties of the density matrix's partial transpose ρ_{12}^{Γ}. The density of states of ρ_{12}^{Γ} is found to be close to the Wigner's semicircle law with these large deviations. The entanglement properties are captured very well by a simple random matrix model for the partial transpose. The model predicts the entanglement transition across a critical large deviation parameter ζ. Log negativity is used to quantify the entanglement between subsystems 1 and 2. Analytical formulas for it are derived using the simple model. Numerical simulations are in excellent agreement with the analytical results.

  11. Soiling of building envelope surfaces and its effect on solar reflectance – Part III: Interlaboratory study of an accelerated aging method for roofing materials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sleiman, Mohamad; Chen, Sharon; Gilbert, Haley E.

    A laboratory method to simulate natural exposure of roofing materials has been reported in a companion article. Here in the current article, we describe the results of an international, nine-participant interlaboratory study (ILS) conducted in accordance with ASTM Standard E691-09 to establish the precision and reproducibility of this protocol. The accelerated soiling and weathering method was applied four times by each laboratory to replicate coupons of 12 products representing a wide variety of roofing categories (single-ply membrane, factory-applied coating (on metal), bare metal, field-applied coating, asphalt shingle, modified-bitumen cap sheet, clay tile, and concrete tile). Participants reported initial and laboratory-agedmore » values of solar reflectance and thermal emittance. Measured solar reflectances were consistent within and across eight of the nine participating laboratories. Measured thermal emittances reported by six participants exhibited comparable consistency. For solar reflectance, the accelerated aging method is both repeatable and reproducible within an acceptable range of standard deviations: the repeatability standard deviation sr ranged from 0.008 to 0.015 (relative standard deviation of 1.2–2.1%) and the reproducibility standard deviation sR ranged from 0.022 to 0.036 (relative standard deviation of 3.2–5.8%). The ILS confirmed that the accelerated aging method can be reproduced by multiple independent laboratories with acceptable precision. In conclusion, this study supports the adoption of the accelerated aging practice to speed the evaluation and performance rating of new cool roofing materials.« less

  12. UAE population reference standard charts for body mass index and skinfold thickness, at ages 0-18 years.

    PubMed

    Abdulrazzaq, Yousef M; Nagelkerke, Nico; Moussa, Mohamed A

    2011-11-01

    To determine a range of anthropometric measurements including skinfold thickness measurements in four different areas of the body, to construct population growth charts for body mass index (BMI), skinfolds, and to compare these with growth charts from other countries. One aim was also to validate body fat charts derived from skinfold thickness. A national cross-sectional growth survey of children, 0-18 years old, was conducted using multistage stratified random sampling. The sample size included at least 200 children in each age-sex group. Height, weight, biceps skinfold, triceps skinfold, subscapular skinfold, suprailiac skinfold, and mid-upper-arm circumference were measured in each child. We describe correlation, standard deviation scores relative to the other standards, and calculation of body density in the United Arab Emirates population. We determined whether any of the above is a good indicator of fatness in children. BMI, upper-arm circumference, sum of four skinfolds, and percentage body fat charts were constructed using the LMS method of smoothing. BMI was very significantly correlated with sum of skinfold thicknesses, and mid-upper-arm circumference. Prevalence of obesity and overweight in ages 13-17 years was respectively 9.94% and 15.16% in females and 6.08% and 14.16% in males. Derived body fat charts were found not to be accurate. A national BMI, upper-arm circumference, and sum of four skinfolds chart has been constructed that can be used as a reference standard for the United Arab Emirates. Sum of four skinfold thickness charts can be used as crude determinants of adiposity in children, but derived body fat charts were shown to be inaccurate.

  13. Selection and Classification Using a Forecast Applicant Pool.

    ERIC Educational Resources Information Center

    Hendrix, William H.

    The document presents a forecast model of the future Air Force applicant pool. By forecasting applicants' quality (means and standard deviations of aptitude scores) and quantity (total number of applicants), a potential enlistee could be compared to the forecasted pool. The data used to develop the model consisted of means, standard deviation, and…

  14. Search for the Standard Model Higgs Boson Decaying to Bottom Quarks in Proton-Proton Collisions at 8 TeV

    NASA Astrophysics Data System (ADS)

    Silkworth, Inga

    A search for the standard model Higgs boson (H) decaying to bottom quarks and produced in association with a Z boson is presented. The search uses 8 TeV center-of-mass energy proton-proton collision data recorded by the Compact Muon Solenoid experiment at the Large Hadron Collider corresponding to integrated luminosity of 19.0 inverse femtobarns. The Z boson is reconstructed using two oppositely charged leptons -- either electrons or muons. Two techniques for reconstructing the Higgs candidate are discussed: the standard method using two jets reconstructed with the anti-kt algorithm and a second technique using jet substructure that was developed for highly boosted massive particles. Upper limits, at the 95% confidence level, on the production cross section times the branching ratio, with respect to the standard model expectations, are derived for a Higgs boson in a mass range 110-135 GeV. The results from the ZH channel are combined with five other channels, and an excess of events is observed consistent with the standard model Higgs boson with a local significance of 2.1 standard deviations at 125 GeV.

  15. Test of the principle of operation of a wideband magnetic direction finder for lightning return strokes

    NASA Technical Reports Server (NTRS)

    Herrman, B. D.; Uman, M. A.; Brantley, R. D.; Krider, E. P.

    1976-01-01

    The principle of operation of a wideband crossed-loop magnetic-field direction finder is studied by comparing the bearing determined from the NS and EW magnetic fields at various times up to 155 microsec after return stroke initiation with the TV-determined lightning channel base direction. For 40 lightning strokes in the 3 to 12 km range, the difference between the bearings found from magnetic fields sampled at times between 1 and 10 microsec and the TV channel-base data has a standard deviation of 3-4 deg. Included in this standard deviation is a 2-3 deg measurement error. For fields sampled at progressively later times, both the mean and the standard deviation of the difference between the direction-finder bearing and the TV bearing increase. Near 150 microsec, means are about 35 deg and standard deviations about 60 deg. The physical reasons for the late-time inaccuracies in the wideband direction finder and the occurrence of these effects in narrow-band VLF direction finders are considered.

  16. Wavelength selection method with standard deviation: application to pulse oximetry.

    PubMed

    Vazquez-Jaccaud, Camille; Paez, Gonzalo; Strojnik, Marija

    2011-07-01

    Near-infrared spectroscopy provides useful biological information after the radiation has penetrated through the tissue, within the therapeutic window. One of the significant shortcomings of the current applications of spectroscopic techniques to a live subject is that the subject may be uncooperative and the sample undergoes significant temporal variations, due to his health status that, from radiometric point of view, introduce measurement noise. We describe a novel wavelength selection method for monitoring, based on a standard deviation map, that allows low-noise sensitivity. It may be used with spectral transillumination, transmission, or reflection signals, including those corrupted by noise and unavoidable temporal effects. We apply it to the selection of two wavelengths for the case of pulse oximetry. Using spectroscopic data, we generate a map of standard deviation that we propose as a figure-of-merit in the presence of the noise introduced by the living subject. Even in the presence of diverse sources of noise, we identify four wavelength domains with standard deviation, minimally sensitive to temporal noise, and two wavelengths domains with low sensitivity to temporal noise.

  17. Estimation of Tooth Size Discrepancies among Different Malocclusion Groups.

    PubMed

    Hasija, Narender; Bala, Madhu; Goyal, Virender

    2014-05-01

    Regards and Tribute: Late Dr Narender Hasija was a mentor and visionary in the light of knowledge and experience. We pay our regards with deepest gratitude to the departed soul to rest in peace. Bolton's ratios help in estimating overbite, overjet relationships, the effects of contemplated extractions on posterior occlusion, incisor relationships and identification of occlusal misfit produced by tooth size discrepancies. To determine any difference in tooth size discrepancy in anterior as well as overall ratio in different malocclusions and comparison with Bolton's study. After measuring the teeth on all 100 patients, Bolton's analysis was performed. Results were compared with Bolton's means and standard deviations. The results were also subjected to statistical analysis. Results show that the mean and standard deviations of ideal occlusion cases are comparable with those Bolton but, when the mean and standard deviation of malocclusion groups are compared with those of Bolton, the values of standard deviation are higher, though the mean is comparable. How to cite this article: Hasija N, Bala M, Goyal V. Estimation of Tooth Size Discrepancies among Different Malocclusion Groups. Int J Clin Pediatr Dent 2014;7(2):82-85.

  18. Association of auricular pressing and heart rate variability in pre-exam anxiety students.

    PubMed

    Wu, Wocao; Chen, Junqi; Zhen, Erchuan; Huang, Huanlin; Zhang, Pei; Wang, Jiao; Ou, Yingyi; Huang, Yong

    2013-03-25

    A total of 30 students scoring between 12 and 20 on the Test Anxiety Scale who had been exhibiting an anxious state > 24 hours, and 30 normal control students were recruited. Indices of heart rate variability were recorded using an Actiheart electrocardiogram recorder at 10 minutes before auricular pressing, in the first half of stimulation and in the second half of stimulation. The results revealed that the standard deviation of all normal to normal intervals and the root mean square of standard deviation of normal to normal intervals were significantly increased after stimulation. The heart rate variability triangular index, very-low-frequency power, low-frequency power, and the ratio of low-frequency to high-frequency power were increased to different degrees after stimulation. Compared with normal controls, the root mean square of standard deviation of normal to normal intervals was significantly increased in anxious students following auricular pressing. These results indicated that auricular pressing can elevate heart rate variability, especially the root mean square of standard deviation of normal to normal intervals in students with pre-exam anxiety.

  19. Association of auricular pressing and heart rate variability in pre-exam anxiety students

    PubMed Central

    Wu, Wocao; Chen, Junqi; Zhen, Erchuan; Huang, Huanlin; Zhang, Pei; Wang, Jiao; Ou, Yingyi; Huang, Yong

    2013-01-01

    A total of 30 students scoring between 12 and 20 on the Test Anxiety Scale who had been exhibiting an anxious state > 24 hours, and 30 normal control students were recruited. Indices of heart rate variability were recorded using an Actiheart electrocardiogram recorder at 10 minutes before auricular pressing, in the first half of stimulation and in the second half of stimulation. The results revealed that the standard deviation of all normal to normal intervals and the root mean square of standard deviation of normal to normal intervals were significantly increased after stimulation. The heart rate variability triangular index, very-low-frequency power, low-frequency power, and the ratio of low-frequency to high-frequency power were increased to different degrees after stimulation. Compared with normal controls, the root mean square of standard deviation of normal to normal intervals was significantly increased in anxious students following auricular pressing. These results indicated that auricular pressing can elevate heart rate variability, especially the root mean square of standard deviation of normal to normal intervals in students with pre-exam anxiety. PMID:25206734

  20. Enhancing Scheduling Performance for a Wafer Fabrication Factory: The Biobjective Slack-Diversifying Nonlinear Fluctuation-Smoothing Rule

    PubMed Central

    Chen, Toly; Wang, Yu Cheng

    2012-01-01

    A biobjective slack-diversifying nonlinear fluctuation-smoothing rule (biSDNFS) is proposed in the present work to improve the scheduling performance of a wafer fabrication factory. This rule was derived from a one-factor bi-objective nonlinear fluctuation-smoothing rule (1f-biNFS) by dynamically maximizing the standard deviation of the slack, which has been shown to benefit scheduling performance by several previous studies. The efficacy of the biSDNFS was validated with a simulated case; evidence was found to support its effectiveness. We also suggested several directions in which it can be exploited in the future. PMID:23509446

  1. Evaluation of random errors in Williams’ series coefficients obtained with digital image correlation

    NASA Astrophysics Data System (ADS)

    Lychak, Oleh V.; Holyns'kiy, Ivan S.

    2016-03-01

    The use of the Williams’ series parameters for fracture analysis requires valid information about their error values. The aim of this investigation is the development of the method for estimation of the standard deviation of random errors of the Williams’ series parameters, obtained from the measured components of the stress field. Also, the criteria for choosing the optimal number of terms in the truncated Williams’ series for derivation of their parameters with minimal errors is proposed. The method was used for the evaluation of the Williams’ parameters, obtained from the data, and measured by the digital image correlation technique for testing a three-point bending specimen.

  2. Experimental test of nonlocal realistic theories without the rotational symmetry assumption.

    PubMed

    Paterek, Tomasz; Fedrizzi, Alessandro; Gröblacher, Simon; Jennewein, Thomas; Zukowski, Marek; Aspelmeyer, Markus; Zeilinger, Anton

    2007-11-23

    We analyze the class of nonlocal realistic theories that was originally considered by Leggett [Found. Phys. 33, 1469 (2003)10.1023/A:1026096313729] and tested by us in a recent experiment [Nature (London) 446, 871 (2007)10.1038/nature05677]. We derive an incompatibility theorem that works for finite numbers of polarizer settings and that does not require the previously assumed rotational symmetry of the two-particle correlation functions. The experimentally measured case involves seven different measurement settings. Using polarization-entangled photon pairs, we exclude this broader class of nonlocal realistic models by experimentally violating a new Leggett-type inequality by 80 standard deviations.

  3. An improved method for predicting the effects of flight on jet mixing noise

    NASA Technical Reports Server (NTRS)

    Stone, J. R.

    1979-01-01

    A method for predicting the effects of flight on jet mixing noise has been developed on the basis of the jet noise theory of Ffowcs-Williams (1963) and data derived from model-jet/free-jet simulated flight tests. Predicted and experimental values are compared for the J85 turbojet engine on the Bertin Aerotrain, the low-bypass refanned JT8D engine on a DC-9, and the high-bypass JT9D engine on a DC-10. Over the jet velocity range from 280 to 680 m/sec, the predictions show a standard deviation of 1.5 dB.

  4. Offshore fatigue design turbulence

    NASA Astrophysics Data System (ADS)

    Larsen, Gunner C.

    2001-07-01

    Fatigue damage on wind turbines is mainly caused by stochastic loading originating from turbulence. While onshore sites display large differences in terrain topology, and thereby also in turbulence conditions, offshore sites are far more homogeneous, as the majority of them are likely to be associated with shallow water areas. However, despite this fact, specific recommendations on offshore turbulence intensities, applicable for fatigue design purposes, are lacking in the present IEC code. This article presents specific guidelines for such loading. These guidelines are based on the statistical analysis of a large number of wind data originating from two Danish shallow water offshore sites. The turbulence standard deviation depends on the mean wind speed, upstream conditions, measuring height and thermal convection. Defining a population of turbulence standard deviations, at a given measuring position, uniquely by the mean wind speed, variations in upstream conditions and atmospheric stability will appear as variability of the turbulence standard deviation. Distributions of such turbulence standard deviations, conditioned on the mean wind speed, are quantified by fitting the measured data to logarithmic Gaussian distributions. By combining a simple heuristic load model with the parametrized conditional probability density functions of the turbulence standard deviations, an empirical offshore design turbulence intensity is determined. For pure stochastic loading (as associated with standstill situations), the design turbulence intensity yields a fatigue damage equal to the average fatigue damage caused by the distributed turbulence intensity. If the stochastic loading is combined with a periodic deterministic loading (as in the normal operating situation), the proposed design turbulence intensity is shown to be conservative.

  5. Estimating extreme stream temperatures by the standard deviate method

    NASA Astrophysics Data System (ADS)

    Bogan, Travis; Othmer, Jonathan; Mohseni, Omid; Stefan, Heinz

    2006-02-01

    It is now widely accepted that global climate warming is taking place on the earth. Among many other effects, a rise in air temperatures is expected to increase stream temperatures indefinitely. However, due to evaporative cooling, stream temperatures do not increase linearly with increasing air temperatures indefinitely. Within the anticipated bounds of climate warming, extreme stream temperatures may therefore not rise substantially. With this concept in mind, past extreme temperatures measured at 720 USGS stream gauging stations were analyzed by the standard deviate method. In this method the highest stream temperatures are expressed as the mean temperature of a measured partial maximum stream temperature series plus its standard deviation multiplied by a factor KE (standard deviate). Various KE-values were explored; values of KE larger than 8 were found physically unreasonable. It is concluded that the value of KE should be in the range from 7 to 8. A unit error in estimating KE translates into a typical stream temperature error of about 0.5 °C. Using a logistic model for the stream temperature/air temperature relationship, a one degree error in air temperature gives a typical error of 0.16 °C in stream temperature. With a projected error in the enveloping standard deviate dKE=1.0 (range 0.5-1.5) and an error in projected high air temperature d Ta=2 °C (range 0-4 °C), the total projected stream temperature error is estimated as d Ts=0.8 °C.

  6. Herschel Extreme Lensing Line Observations: Dynamics of Two Strongly Lensed Star-Forming Galaxies near Redshift z=2*

    NASA Technical Reports Server (NTRS)

    Rhoads, James E.; Rigby, Jane Rebecca; Malhotra, Sangeeta; Allam, Sahar; Carilli, Chris; Combes, Francoise; Finkelstein, Keely; Finkelstein, Steven; Frye, Brenda; Gerin, Maryvonne; hide

    2014-01-01

    We report on two regularly rotating galaxies at redshift z approx. = 2, using high-resolution spectra of the bright [C microns] 158 micrometers emission line from the HIFI instrument on the Herschel Space Observatory. Both SDSS090122.37+181432.3 ("S0901") and SDSSJ120602.09+514229.5 ("the Clone") are strongly lensed and show the double-horned line profile that is typical of rotating gas disks. Using a parametric disk model to fit the emission line profiles, we find that S0901 has a rotation speed of v sin(i) approx. = 120 +/- 7 kms(sup -1) and a gas velocity dispersion of (standard deviation)g < 23 km s(sup -1) (1(standard deviation)). The best-fitting model for the Clone is a rotationally supported disk having v sin(i) approx. = 79 +/- 11 km s(sup -1) and (standard deviation)g 4 kms(sup -1) (1(standard deviation)). However, the Clone is also consistent with a family of dispersion-dominated models having (standard deviation)g = 92 +/- 20 km s(sup -1). Our results showcase the potential of the [C microns] line as a kinematic probe of high-redshift galaxy dynamics: [C microns] is bright, accessible to heterodyne receivers with exquisite velocity resolution, and traces dense star-forming interstellar gas. Future [C microns] line observations with ALMA would offer the further advantage of spatial resolution, allowing a clearer separation between rotation and velocity dispersion.

  7. Application of derivative ratio spectrophotometry for determination of β-carotene and astaxanthin from Phaffia rhodozyma extract*

    PubMed Central

    Ni, Hui; He, Guo-qing; Ruan, Hui; Chen, Qi-he; Chen, Feng

    2005-01-01

    A derivative ratio spectrophotometric method was used for the simultaneous determination of β-carotene and astaxanthin produced from Phaffia rhodozyma. Absorbencies of a series of the standard carotenoids in the range of 441 nm to 490 nm demonstrated that their absorptive spectra accorded with Beer’s law and that the additivity when the concentrations of β-carotene and astaxanthin and their mixture were within the range of 0 to 5 µg/ml, 0 to 6 µg/ml, and 0 to 6 µg/ml, respectively. When the wavelength interval (Δλ) at 2 nm was selected to calculate the first derivative ratio spectra values, the first derivative amplitudes at 461 nm and 466 nm were suitable for quantitatively determining β-carotene and astaxanthin, respectively. Effect of divisor on derivative ratio spectra could be neglected; any concentration used as divisor in range of 1.0 to 4.0 µg/ml is ideal for calculating the derivative ratio spectra values of the two carotenoids. Calibration graphs were established for β-carotene within 0–6.0 µg/ml and for astaxanthin within 0–5.0 µg/ml with their corresponding regressive equations in: y=−0.0082x−0.0002 and y=0.0146x−0.0006, respectively. R-square values in excess of 0.999 indicated the good linearity of the calibration graphs. Sample recovery rates were found satisfactory (>99%) with relative standard deviations (RSD) of less than 5%. This method was successfully applied to simultaneous determination of β-carotene and astaxanthin in the laboratory-prepared mixtures and the extract from the Phaffia rhodozyma culture. PMID:15909336

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fried, D; Meier, J; Mawlawi, O

    Purpose: Use a NEMA-IEC PET phantom to assess the robustness of FDG-PET-based radiomics features to changes in reconstruction parameters across different scanners. Methods: We scanned a NEMA-IEC PET phantom on 3 different scanners (GE Discovery VCT, GE Discovery 710, and Siemens mCT) using a FDG source-to-background ratio of 10:1. Images were retrospectively reconstructed using different iterations (2–3), subsets (21–24), Gaussian filter widths (2, 4, 6mm), and matrix sizes (128,192,256). The 710 and mCT used time-of-flight and point-spread-functions in reconstruction. The axial-image through the center of the 6 active spheres was used for analysis. A region-of-interest containing all spheres was ablemore » to simulate a heterogeneous lesion due to partial volume effects. Maximum voxel deviations from all retrospectively reconstructed images (18 per scanner) was compared to our standard clinical protocol. PET Images from 195 non-small cell lung cancer patients were used to compare feature variation. The ratio of a feature’s standard deviation from the patient cohort versus the phantom images was calculated to assess for feature robustness. Results: Across all images, the percentage of voxels differing by <1SUV and <2SUV ranged from 61–92% and 88–99%, respectively. Voxel-voxel similarity decreased when using higher resolution image matrices (192/256 versus 128) and was comparable across scanners. Taking the ratio of patient and phantom feature standard deviation was able to identify features that were not robust to changes in reconstruction parameters (e.g. co-occurrence correlation). Metrics found to be reasonably robust (standard deviation ratios > 3) were observed for routinely used SUV metrics (e.g. SUVmean and SUVmax) as well as some radiomics features (e.g. co-occurrence contrast, co-occurrence energy, standard deviation, and uniformity). Similar standard deviation ratios were observed across scanners. Conclusions: Our method enabled a comparison of feature variability across scanners and was able to identify features that were not robust to changes in reconstruction parameters.« less

  9. Host model uncertainties in aerosol radiative forcing estimates: results from the AeroCom prescribed intercomparison study

    NASA Astrophysics Data System (ADS)

    Stier, P.; Schutgens, N. A. J.; Bian, H.; Boucher, O.; Chin, M.; Ghan, S.; Huneeus, N.; Kinne, S.; Lin, G.; Myhre, G.; Penner, J. E.; Randles, C.; Samset, B.; Schulz, M.; Yu, H.; Zhou, C.

    2012-09-01

    Simulated multi-model "diversity" in aerosol direct radiative forcing estimates is often perceived as measure of aerosol uncertainty. However, current models used for aerosol radiative forcing calculations vary considerably in model components relevant for forcing calculations and the associated "host-model uncertainties" are generally convoluted with the actual aerosol uncertainty. In this AeroCom Prescribed intercomparison study we systematically isolate and quantify host model uncertainties on aerosol forcing experiments through prescription of identical aerosol radiative properties in nine participating models. Even with prescribed aerosol radiative properties, simulated clear-sky and all-sky aerosol radiative forcings show significant diversity. For a purely scattering case with globally constant optical depth of 0.2, the global-mean all-sky top-of-atmosphere radiative forcing is -4.51 W m-2 and the inter-model standard deviation is 0.70 W m-2, corresponding to a relative standard deviation of 15%. For a case with partially absorbing aerosol with an aerosol optical depth of 0.2 and single scattering albedo of 0.8, the forcing changes to 1.26 W m-2, and the standard deviation increases to 1.21 W m-2, corresponding to a significant relative standard deviation of 96%. However, the top-of-atmosphere forcing variability owing to absorption is low, with relative standard deviations of 9% clear-sky and 12% all-sky. Scaling the forcing standard deviation for a purely scattering case to match the sulfate radiative forcing in the AeroCom Direct Effect experiment, demonstrates that host model uncertainties could explain about half of the overall sulfate forcing diversity of 0.13 W m-2 in the AeroCom Direct Radiative Effect experiment. Host model errors in aerosol radiative forcing are largest in regions of uncertain host model components, such as stratocumulus cloud decks or areas with poorly constrained surface albedos, such as sea ice. Our results demonstrate that host model uncertainties are an important component of aerosol forcing uncertainty that require further attention.

  10. Robust Alternatives to the Standard Deviation in Processing of Physics Experimental Data

    NASA Astrophysics Data System (ADS)

    Shulenin, V. P.

    2016-10-01

    Properties of robust estimations of the scale parameter are studied. It is noted that the median of absolute deviations and the modified estimation of the average Gini differences have asymptotically normal distributions and bounded influence functions, are B-robust estimations, and hence, unlike the estimation of the standard deviation, are protected from the presence of outliers in the sample. Results of comparison of estimations of the scale parameter are given for a Gaussian model with contamination. An adaptive variant of the modified estimation of the average Gini differences is considered.

  11. Distribution of the two-sample t-test statistic following blinded sample size re-estimation.

    PubMed

    Lu, Kaifeng

    2016-05-01

    We consider the blinded sample size re-estimation based on the simple one-sample variance estimator at an interim analysis. We characterize the exact distribution of the standard two-sample t-test statistic at the final analysis. We describe a simulation algorithm for the evaluation of the probability of rejecting the null hypothesis at given treatment effect. We compare the blinded sample size re-estimation method with two unblinded methods with respect to the empirical type I error, the empirical power, and the empirical distribution of the standard deviation estimator and final sample size. We characterize the type I error inflation across the range of standardized non-inferiority margin for non-inferiority trials, and derive the adjusted significance level to ensure type I error control for given sample size of the internal pilot study. We show that the adjusted significance level increases as the sample size of the internal pilot study increases. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  12. Study of the optimum level of electrode placement for the evaluation of absolute lung resistivity with the Mk3.5 EIT system.

    PubMed

    Nebuya, S; Noshiro, M; Yonemoto, A; Tateno, S; Brown, B H; Smallwood, R H; Milnes, P

    2006-05-01

    Inter-subject variability has caused the majority of previous electrical impedance tomography (EIT) techniques to focus on the derivation of relative or difference measures of in vivo tissue resistivity. Implicit in these techniques is the requirement for a reference or previously defined data set. This study assesses the accuracy and optimum electrode placement strategy for a recently developed method which estimates an absolute value of organ resistivity without recourse to a reference data set. Since this measurement of tissue resistivity is absolute, in Ohm metres, it should be possible to use EIT measurements for the objective diagnosis of lung diseases such as pulmonary oedema and emphysema. However, the stability and reproducibility of the method have not yet been investigated fully. To investigate these problems, this study used a Sheffield Mk3.5 system which was configured to operate with eight measurement electrodes. As a result of this study, the absolute resistivity measurement was found to be insensitive to the electrode level between 4 and 5 cm above the xiphoid process. The level of the electrode plane was varied between 2 cm and 7 cm above the xiphoid process. Absolute lung resistivity in 18 normal subjects (age 22.6 +/- 4.9, height 169.1 +/- 5.7 cm, weight 60.6 +/- 4.5 kg, body mass index 21.2 +/- 1.6: mean +/- standard deviation) was measured during both normal and deep breathing for 1 min. Three sets of measurements were made over a period of several days on each of nine of the normal male subjects. No significant differences in absolute lung resistivity were found, either during normal tidal breathing between the electrode levels of 4 and 5 cm (9.3 +/- 2.4 Omega m, 9.6 +/- 1.9 Omega m at 4 and 5 cm, respectively: mean +/- standard deviation) or during deep breathing between the electrode levels of 4 and 5 cm (10.9 +/- 2.9 Omega m and 11.1 +/- 2.3 Omega m, respectively: mean +/- standard deviation). However, the differences in absolute lung resistivity between normal and deep tidal breathing at the same electrode level are significant. No significant difference was found in the coefficient of variation between the electrode levels of 4 and 5 cm (9.5 +/- 3.6%, 8.5 +/- 3.2% at 4 and 5 cm, respectively: mean +/- standard deviation in individual subjects). Therefore, the electrode levels of 4 and 5 cm above the xiphoid process showed reasonable reliability in the measurement of absolute lung resistivity both among individuals and over time.

  13. Coastal Vertical Land motion in the German Bight

    NASA Astrophysics Data System (ADS)

    Becker, Matthias; Fenoglio, Luciana; Reckeweg, Florian

    2017-04-01

    In the framework of the ESA Sea Level Climate Change Initiative (CCI) we analyse a set of GNSS equipped tide gauges at the German Bight. Main goals are the determination of tropospheric zenith delay corrections for altimetric observations, precise coordinates in ITRF2008 and vertical land motion (VLM) rates of the tide gauge stations. These are to be used for georeferencing the tide gauges and the correction of tide gauge observations for VLM. The set of stations includes 38 GNSS stations. 19 stations are in the German Bight, where 15 of them belong to the Bundesanstalt für Gewässerkunde, 3 to EUREF and 1 to GREF. These stations are collocated with tide gauges (TGs). The other 19 GNSS stations in the network belong to EUREF, IGS and GREF. We analyse data in the time span from 2008 till the end of 2016 with the Bernese PPP processing approach. Data are partly rather noisy and disturbed by offsets and data gaps at the coastal TG sites. Special effort is therefore put into a proper estimation of the VLM. We use FODITS (Ostini2012), HECTOR (Bos et al, 2013), CATS (Williams, 2003) and the MIDAS approach of Blewitt (2016) to robustly derive rates and realistic error estimates. The results are compared to those published by the European Permanent Network (EPN), ITRF and the Système d'Observation du Niveau des Eaux Littorales (SONEL) for common stations. Vertical motion is small in general, at the -1 to -2 mm/yr level for most coastal stations. A comparison of the standard deviations of the velocity differences to EPN with the mean values of the estimated velocity standard deviations for our solution shows a very good agreement of the estimated velocities and their standard deviations with the reference solution from EPN. In the comparison with results by SONEL the standard deviation of the differences is slightly higher. The discrepancies may arise from differences in the time span analyzed and gaps, offsets and data preprocessing. The combined estimation of functional and stochastic parameters is rather sensitive to the characteristics of the time series and thus the estimated velocity also depends on the applied stochastic model and on the selected parameters. The GPS vertical land motion rates are finally compared to the difference between sea level rates measured by co-located altimetry and by tide gauge station data, which gives another estimation of VLM.

  14. 40 CFR 63.7751 - What reports must I submit and when?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... deviations from any emissions limitations (including operating limit), work practice standards, or operation and maintenance requirements, a statement that there were no deviations from the emissions limitations...-of-control during the reporting period. (7) For each deviation from an emissions limitation...

  15. Comparison of Psychophysical and Physical Measurements of Real Ear to Coupler Differences.

    PubMed

    Koning, Raphael; Wouters, Jan; Francart, Tom

    2015-01-01

    The purpose of the study is to compare real ear to coupler difference (RECD) curves based on physical and psychophysical measures. For the physically measured RECD, the RECD was measured with real ear and coupler measurements for the ear simulator and HA1- and HA2 2-cc couplers. The psychophysically measured RECDs were derived from audiogram measures. RECDs were measured in 19 normally hearing subjects. The coupler measurement was done with the probe microphone and the coupler microphone itself. Psychophysically measured RECDs were derived for all subjects by measuring the audiogram in sound field and with an ER-3A insert phone. Reference data were obtained for the three coupler types. It was possible to derive the RECD curve with psychophysical methods. There was no overall statistical difference between the physically and psychophysically measured RECD curves for the HA2 2-cc coupler and the ear simulator. The standard deviation was, however, much higher for the psychophysically derived RECD, indicating that physically measured RECDs are more precise than psychophysically derived RECDs. For the physical RECD measurements, the coupler microphone should be used for the coupler measurement. Physically measured RECDs were validated on group level by the reliable derivation of the RECD curve from audiogram measures.

  16. Evaluation of breathing patterns for respiratory-gated radiation therapy using the respiration regularity index

    NASA Astrophysics Data System (ADS)

    Cheong, Kwang-Ho; Lee, MeYeon; Kang, Sei-Kwon; Yoon, Jai-Woong; Park, SoAh; Hwang, Taejin; Kim, Haeyoung; Kim, KyoungJu; Han, Tae Jin; Bae, Hoonsik

    2015-01-01

    Despite the considerable importance of accurately estimating the respiration regularity of a patient in motion compensation treatment, not to mention the necessity of maintaining that regularity through the following sessions, an effective and simply applicable method by which those goals can be accomplished has rarely been reported. The authors herein propose a simple respiration regularity index based on parameters derived from a correspondingly simplified respiration model. In order to simplify a patient's breathing pattern while preserving the data's intrinsic properties, we defined a respiration model as a cos4( ω( t) · t) wave form with a baseline drift. According to this respiration formula, breathing-pattern fluctuation could be explained using four factors: the sample standard deviation of respiration period ( s f ), the sample standard deviation of amplitude ( s a ) and the results of a simple regression of the baseline drift (slope as β, and standard deviation of residuals as σ r ) of a respiration signal. The overall irregularity ( δ) was defined as , where is a variable newly-derived by using principal component analysis (PCA) for the four fluctuation parameters and has two principal components ( ω 1, ω 2). The proposed respiration regularity index was defined as ρ = ln(1 + (1/ δ))/2, a higher ρ indicating a more regular breathing pattern. We investigated its clinical relevance by comparing it with other known parameters. Subsequently, we applied it to 110 respiration signals acquired from five liver and five lung cancer patients by using real-time position management (RPM; Varian Medical Systems, Palo Alto, CA). Correlations between the regularity of the first session and the remaining fractions were investigated using Pearson's correlation coefficient. Additionally, the respiration regularity was compared between the liver and lung cancer patient groups. The respiration regularity was determined based on ρ; patients with ρ < 0.3 showed worse regularity than the others whereas ρ > 0.7 was suitable for respiratory-gated radiation therapy (RGRT). Fluctuations in the breathing cycle and the amplitude were especially determinative of ρ. If the respiration regularity of a patient's first session was known, it could be estimated through subsequent sessions. Notably, the breathing patterns of the lung cancer patients were more irregular than those of the liver cancer patients. Respiration regularity could be objectively determined by using a composite index, ρ. Such a single-index testing of respiration regularity can facilitate determination of RGRT availability in clinical settings, especially for free-breathing cases.

  17. LASER BIOLOGY AND MEDICINE: Arterial pulse shape measurement using self-mixing effect in a diode laser

    NASA Astrophysics Data System (ADS)

    Hast, J.; Myllylä, Risto; Sorvoja, H.; Miettinen, J.

    2002-11-01

    The self-mixing effect in a diode laser and the Doppler technique are used for quantitative measurements of the cardiovascular pulses from radial arteries of human individuals. 738 cardiovascular pulses from 10 healthy volunteers were studied. The Doppler spectrograms reconstructed from the Doppler signal, which is measured from the radial displacement of the radial artery, are compared to the first derivative of the blood pressure signals measured from the middle finger by the Penaz technique. The mean correlation coefficient between the Doppler spectrograms and the first derivative of the blood pressure signals was 0.84, with a standard deviation of 0.05. Pulses with the correlation coefficient less than 0.7 were neglected in the study. Percentage of successfully detected pulses was 95.7%. It is shown that cardiovascular pulse shape from the radial artery can be measured noninvasively by using the self-mixing interferometry.

  18. Baseline Maritime Aerosol: Methodology to Derive the Optical Thickness and Scattering Properties

    NASA Technical Reports Server (NTRS)

    Kaufman, Yoram J.; Smirnov, Alexander; Holben, Brent N.; Dubovik, Oleg; Einaudi, Franco (Technical Monitor)

    2001-01-01

    Satellite Measurements of the global distribution of aerosol and their effect on climate should be viewed in respect to a baseline aerosol. In this concept, concentration of fine mode aerosol particles is elevated above the baseline by man-made activities (smoke or urban pollution), while coarse mode by natural processes (e.g. dust or sea-spray). Using 1-3 years of measurements in 10 stations of the Aerosol Robotic network (ACRONET we develop a methodology and derive the optical thickness and properties of this baseline aerosol for the Pacific and Atlantic Oceans. Defined as the median for periods of stable optical thickness (standard deviation < 0.02) during 2-6 days, the median baseline aerosol optical thickness over the Pacific Ocean is 0.052 at 500 am with Angstrom exponent of 0.77, and 0.071 and 1.1 respectively, over the Atlantic Ocean.

  19. Controlling effect of geometrically defined local structural changes on chaotic Hamiltonian systems.

    PubMed

    Ben Zion, Yossi; Horwitz, Lawrence

    2010-04-01

    An effective characterization of chaotic conservative Hamiltonian systems in terms of the curvature associated with a Riemannian metric tensor derived from the structure of the Hamiltonian has been extended to a wide class of potential models of standard form through definition of a conformal metric. The geodesic equations reproduce the Hamilton equations of the original potential model through an inverse map in the tangent space. The second covariant derivative of the geodesic deviation in this space generates a dynamical curvature, resulting in (energy-dependent) criteria for unstable behavior different from the usual Lyapunov criteria. We show here that this criterion can be constructively used to modify locally the potential of a chaotic Hamiltonian model in such a way that stable motion is achieved. Since our criterion for instability is local in coordinate space, these results provide a minimal method for achieving control of a chaotic system.

  20. Gas chromatographic analysis of fatty acid methyl esters of milk fat by an ionic liquid derived from L-phenylalanine as the stationary phase.

    PubMed

    Mendoza, Laura González; González-Álvarez, Jaime; Gonzalo, Carla Fernández; Arias-Abrodo, Pilar; Altava, Belén; Luis, Santiago V; Burguete, Maria Isabel; Gutiérrez-Álvarez, María Dolores

    2015-10-01

    A Gas Chromatography (GC) method has been developed for the separation and characterization of the different fatty acids in anhydrous milk fat (AMF) by means of an ionic liquid stationary phase, characterized by a monocationic imidazolium salt derived from L-phenylalanine. The inner surface of a fused silica capillary column was modified using this ionic liquid functionality and 3-aminopropyldiethoxymethyl silane. This coated GC column, which exhibited good thermal stability (270°C) and good efficiency (2700 plates/m), has been characterized using the Abraham solvation parameter model. The intra-day and inter-day precision of the method have been evaluated, obtaining relative standard deviations (RSD) from 0.99% to 4.0% and from 2.8% to 9.2%, respectively. Furthermore, recoveries from 90% and 99% have been achieved. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. It's time to move on from the bell curve.

    PubMed

    Robinson, Lawrence R

    2017-11-01

    The bell curve was first described in the 18th century by de Moivre and Gauss to depict the distribution of binomial events, such as coin tossing, or repeated measures of physical objects. In the 19th and 20th centuries, the bell curve was appropriated, or perhaps misappropriated, to apply to biologic and social measures across people. For many years we used it to derive reference values for our electrophysiologic studies. There is, however, no reason to believe that electrophysiologic measures should approximate a bell-curve distribution, and empiric evidence suggests they do not. The concept of using mean ± 2 standard deviations should be abandoned. Reference values are best derived by using non-parametric analyses, such as percentile values. This proposal aligns with the recommendation of the recent normative data task force of the American Association of Neuromuscular & Electrodiagnostic Medicine and follows sound statistical principles. Muscle Nerve 56: 859-860, 2017. © 2017 Wiley Periodicals, Inc.

  2. Combining uncertainty factors in deriving human exposure levels of noncarcinogenic toxicants.

    PubMed

    Kodell, R L; Gaylor, D W

    1999-01-01

    Acceptable levels of human exposure to noncarcinogenic toxicants in environmental and occupational settings generally are derived by reducing experimental no-observed-adverse-effect levels (NOAELs) or benchmark doses (BDs) by a product of uncertainty factors (Barnes and Dourson, Ref. 1). These factors are presumed to ensure safety by accounting for uncertainty in dose extrapolation, uncertainty in duration extrapolation, differential sensitivity between humans and animals, and differential sensitivity among humans. The common default value for each uncertainty factor is 10. This paper shows how estimates of means and standard deviations of the approximately log-normal distributions of individual uncertainty factors can be used to estimate percentiles of the distribution of the product of uncertainty factors. An appropriately selected upper percentile, for example, 95th or 99th, of the distribution of the product can be used as a combined uncertainty factor to replace the conventional product of default factors.

  3. Modeling the gas-phase thermochemistry of organosulfur compounds.

    PubMed

    Vandeputte, Aäron G; Sabbe, Maarten K; Reyniers, Marie-Françoise; Marin, Guy B

    2011-06-27

    Key to understanding the involvement of organosulfur compounds in a variety of radical chemistries, such as atmospheric chemistry, polymerization, pyrolysis, and so forth, is knowledge of their thermochemical properties. For organosulfur compounds and radicals, thermochemical data are, however, much less well documented than for hydrocarbons. The traditional recourse to the Benson group additivity method offers no solace since only a very limited number of group additivity values (GAVs) is available. In this work, CBS-QB3 calculations augmented with 1D hindered rotor corrections for 122 organosulfur compounds and 45 organosulfur radicals were used to derive 93 Benson group additivity values, 18 ring-strain corrections, 2 non-nearest-neighbor interactions, and 3 resonance corrections for standard enthalpies of formation, standard molar entropies, and heat capacities for organosulfur compounds and organosulfur radicals. The reported GAVs are consistent with previously reported GAVs for hydrocarbons and hydrocarbon radicals and include 77 contributions, among which 26 radical contributions, which, to the best of our knowledge, have not been reported before. The GAVs allow one to estimate the standard enthalpies of formation at 298 K, the standard entropies at 298 K, and standard heat capacities in the temperature range 300-1500 K for a large set of organosulfur compounds, that is, thiols, thioketons, polysulfides, alkylsulfides, thials, dithioates, and cyclic sulfur compounds. For a validation set of 26 organosulfur compounds, the mean absolute deviation between experimental and group additively modeled enthalpies of formation amounts to 1.9  kJ  mol(-1). For an additional set of 14 organosulfur compounds, it was shown that the mean absolute deviations between calculated and group additively modeled standard entropies and heat capacities are restricted to 4 and 2 J  mol(-1)  K(-1), respectively. As an alternative to Benson GAVs, 26 new hydrogen-bond increments are reported, which can also be useful for the prediction of radical thermochemistry. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Precise determination of δ88Sr in rocks, minerals, and waters by double-spike TIMS: A powerful tool in the study of chemical, geologic, hydrologic and biologic processes

    USGS Publications Warehouse

    Neymark, Leonid A.; Premo, Wayne R.; Mel'nikov, Nikolay N.; Emsbo, Poul

    2014-01-01

    We present strontium isotopic (88Sr/86Sr and 87Sr/86Sr) results obtained by 87Sr–84Sr double spike thermal ionization mass-spectrometry (DS-TIMS) for several standards as well as natural water samples and mineral samples of abiogenic and biogenic origin. The detailed data reduction algorithm and a user-friendly Sr-specific stand-alone computer program used for the spike calibration and the data reduction are also presented. Accuracy and precision of our δ88Sr measurements, calculated as permil (‰) deviations from the NIST SRM-987 standard, were evaluated by analyzing the NASS-6 seawater standard, which yielded δ88Sr = 0.378 ± 0.009‰. The first DS-TIMS data for the NIST SRM-607 potassium feldspar standard and for several US Geological Survey carbonate, phosphate, and silicate standards (EN-1, MAPS-4, MAPS-5, G-3, BCR-2, and BHVO-2) are also reported. Data obtained during this work for Sr-bearing solids and natural waters show a range of δ88Sr values of about 2.4‰, the widest observed so far in terrestrial materials. This range is easily resolvable analytically because the demonstrated external error (±SD, standard deviation) for measured δ88Sr values is typically ≤0.02‰. It is shown that the “true” 87Sr/86Sr value obtained by the DS-TIMS or any other external normalization method combines radiogenic and mass-dependent mass-fractionation effects, which cannot be separated. Therefore, the “true” 87Sr/86Sr and the δ87Sr parameter derived from it are not useful isotope tracers. Data presented in this paper for a wide range of naturally occurring sample types demonstrate the potential of the δ88Sr isotope tracer in combination with the traditional radiogenic 87Sr/86Sr tracer for studying a variety of biological, hydrological, and geological processes.

  5. An isotope-dilution standard GC/MS/MS method for steroid hormones in water

    USGS Publications Warehouse

    Foreman, William T.; Gray, James L.; ReVello, Rhiannon C.; Lindley, Chris E.; Losche, Scott A.

    2013-01-01

    An isotope-dilution quantification method was developed for 20 natural and synthetic steroid hormones and additional compounds in filtered and unfiltered water. Deuterium- or carbon-13-labeled isotope-dilution standards (IDSs) are added to the water sample, which is passed through an octadecylsilyl solid-phase extraction (SPE) disk. Following extract cleanup using Florisil SPE, method compounds are converted to trimethylsilyl derivatives and analyzed by gas chromatography with tandem mass spectrometry. Validation matrices included reagent water, wastewater-affected surface water, and primary (no biological treatment) and secondary wastewater effluent. Overall method recovery for all analytes in these matrices averaged 100%; with overall relative standard deviation of 28%. Mean recoveries of the 20 individual analytes for spiked reagent-water samples prepared along with field samples analyzed in 2009–2010 ranged from 84–104%, with relative standard deviations of 6–36%. Detection levels estimated using ASTM International’s D6091–07 procedure range from 0.4 to 4 ng/L for 17 analytes. Higher censoring levels of 100 ng/L for bisphenol A and 200 ng/L for cholesterol and 3-beta-coprostanol are used to prevent bias and false positives associated with the presence of these analytes in blanks. Absolute method recoveries of the IDSs provide sample-specific performance information and guide data reporting. Careful selection of labeled compounds for use as IDSs is important because both inexact IDS-analyte matches and deuterium label loss affect an IDS’s ability to emulate analyte performance. Six IDS compounds initially tested and applied in this method exhibited deuterium loss and are not used in the final method.

  6. An expanded calibration study of the explicitly correlated CCSD(T)-F12b method using large basis set standard CCSD(T) atomization energies.

    PubMed

    Feller, David; Peterson, Kirk A

    2013-08-28

    The effectiveness of the recently developed, explicitly correlated coupled cluster method CCSD(T)-F12b is examined in terms of its ability to reproduce atomization energies derived from complete basis set extrapolations of standard CCSD(T). Most of the standard method findings were obtained with aug-cc-pV7Z or aug-cc-pV8Z basis sets. For a few homonuclear diatomic molecules it was possible to push the basis set to the aug-cc-pV9Z level. F12b calculations were performed with the cc-pVnZ-F12 (n = D, T, Q) basis set sequence and were also extrapolated to the basis set limit using a Schwenke-style, parameterized formula. A systematic bias was observed in the F12b method with the (VTZ-F12/VQZ-F12) basis set combination. This bias resulted in the underestimation of reference values associated with small molecules (valence correlation energies <0.5 E(h)) and an even larger overestimation of atomization energies for bigger systems. Consequently, caution should be exercised in the use of F12b for high accuracy studies. Root mean square and mean absolute deviation error metrics for this basis set combination were comparable to complete basis set values obtained with standard CCSD(T) and the aug-cc-pVDZ through aug-cc-pVQZ basis set sequence. However, the mean signed deviation was an order of magnitude larger. Problems partially due to basis set superposition error were identified with second row compounds which resulted in a weak performance for the smaller VDZ-F12/VTZ-F12 combination of basis sets.

  7. The Combined Application of Impinger System and Permeation Tube for the Generation of Volatile Organic Compound Standard Gas Mixtures at Varying Diluent Flow Rates

    PubMed Central

    Kim, Ki-Hyun; Susaya, Janice; Cho, Jinwoo; Parker, David

    2012-01-01

    Commercial standard gas generators are often complex and expensive devices. The objective of this research was to assess the performance of a simplified glass impinger system for standard gas generation from a permeation tube (PT) device. The performance of the impinger standard gas generation system was assessed for four aromatic VOCs (benzene, toluene, ethylbenzene, and m-xylene; BTEX) at varying flow rates (FR) of 50 to 800 mL·min−1. Because actual permeation rate (APR) values deviated from those computed by the manufacturer's formula (MPR), new empirical relationships were developed to derive the predicted PR (PPR) of the target components. Experimental results corrected by such a formula indicate that the compatibility between the APR and MPR generally increased with low FR, while the reproducibility was generally reduced with decreasing flow rate. Although compatibility between different PRs is at a relatively small and narrow FR range, the use of correction formula is recommendable for the accurate use of PT. PMID:23112641

  8. Use of Standard Deviations as Predictors in Models Using Large-Scale International Data Sets

    ERIC Educational Resources Information Center

    Austin, Bruce; French, Brian; Adesope, Olusola; Gotch, Chad

    2017-01-01

    Measures of variability are successfully used in predictive modeling in research areas outside of education. This study examined how standard deviations can be used to address research questions not easily addressed using traditional measures such as group means based on index variables. Student survey data were obtained from the Organisation for…

  9. Screen Twice, Cut Once: Assessing the Predictive Validity of Teacher Selection Tools

    ERIC Educational Resources Information Center

    Goldhaber, Dan; Grout, Cyrus; Huntington-Klein, Nick

    2015-01-01

    It is well documented that teachers can have profound effects on student outcomes. Empirical estimates find that a one standard deviation increase in teacher quality raises student test achievement by 10 to 25 percent of a standard deviation. More recent evidence shows that the effectiveness of teachers can affect long-term student outcomes, such…

  10. Comparing Measurement Error between Two Different Methods of Measurement of Various Magnitudes

    ERIC Educational Resources Information Center

    Zavorsky, Gerald S.

    2010-01-01

    Measurement error is a common problem in several fields of research such as medicine, physiology, and exercise science. The standard deviation of repeated measurements on the same person is the measurement error. One way of presenting measurement error is called the repeatability, which is 2.77 multiplied by the within subject standard deviation.…

  11. Parabolic trough receiver heat loss and optical efficiency round robin 2015/2016

    NASA Astrophysics Data System (ADS)

    Pernpeintner, Johannes; Schiricke, Björn; Sallaberry, Fabienne; de Jalón, Alberto García; López-Martín, Rafael; Valenzuela, Loreto; de Luca, Antonio; Georg, Andreas

    2017-06-01

    A round robin for parabolic trough receiver heat loss and optical efficiency in the laboratory was performed between five institutions using five receivers in 2015/2016. Heat loss testing was performed at three cartridge heater test benches and one Joule heating test bench in the temperature range between 100 °C and 550 °C. Optical efficiency testing was performed with two spectrometric test bench and one calorimetric test bench. Heat loss testing results showed standard deviations at the order of 6% to 12 % for most temperatures and receivers and a standard deviation of 17 % for one receiver at 100 °C. Optical efficiency is presented normalized for laboratories showing standard deviations of 0.3 % to 1.3 % depending on the receiver.

  12. Benign positional vertigo and hyperuricaemia.

    PubMed

    Adam, A M

    2005-07-01

    To find out if there is any association between serum uric acid level and positional vertigo. A prospective, case controlled study. A private neurological clinic. All patients presenting with vertigo. Ninety patients were seen in this period with 78 males and 19 females. Mean age was 47 +/- 3 years (at 95% confidence level) with a standard deviation of 12.4. Their mean uric acid level was 442 +/- 16 (at 95% confidence level) with a standard deviation of 79.6 umol/l as compared to 291 +/- 17 (at 95% confidence level) with a standard deviation of 79.7 umol/l in the control group. The P-value was less than 0.001. That there is a significant association between high uric acid and benign positional vertigo.

  13. Palus Somni - Anomalies in the correlation of Al/Si X-ray fluorescence intensity ratios and broad-spectrum visible albedos. [lunar surface mineralogy

    NASA Technical Reports Server (NTRS)

    Clark, P. E.; Andre, C. G.; Adler, I.; Weidner, J.; Podwysocki, M.

    1976-01-01

    The positive correlation between Al/Si X-ray fluorescence intensity ratios determined during the Apollo 15 lunar mission and a broad-spectrum visible albedo of the moon is quantitatively established. Linear regression analysis performed on 246 1 degree geographic cells of X-ray fluorescence intensity and visible albedo data points produced a statistically significant correlation coefficient of .78. Three distinct distributions of data were identified as (1) within one standard deviation of the regression line, (2) greater than one standard deviation below the line, and (3) greater than one standard deviation above the line. The latter two distributions of data were found to occupy distinct geographic areas in the Palus Somni region.

  14. Screening Samples for Arsenic by Inductively Coupled Plasma-Mass Spectrometry for Treaty Samples

    DTIC Science & Technology

    2014-02-01

    2.274 3.657 10.06 14.56 30.36 35.93 % RSD : 15.87% 4.375% 2.931% 4.473% 3.349% 3.788% 2.802% 3.883% 3.449% RSD , relative standard deviation 9   Table...107.9% 106.4% Standard Deviation: 0.3171 0.3498 0.8024 2.964 4.526 10.06 13.83 16.38 11.81 % RSD : 5.657% 3.174% 3.035% 5.507% 4.332% 3.795% 2.626...119.1% 116.5% 109.4% 106.8% 105.2% 105.5% 105.8% 108.6% 107.8% Standard Deviation: 0.2379 0.5595 1.173 2.375 2.798 5.973 11.79 15.10 30.54 % RSD

  15. A deviation display method for visualising data in mobile gamma-ray spectrometry.

    PubMed

    Kock, Peder; Finck, Robert R; Nilsson, Jonas M C; Ostlund, Karl; Samuelsson, Christer

    2010-09-01

    A real time visualisation method, to be used in mobile gamma-spectrometric search operations using standard detector systems is presented. The new method, called deviation display, uses a modified waterfall display to present relative changes in spectral data over energy and time. Using unshielded (137)Cs and (241)Am point sources and different natural background environments, the behaviour of the deviation displays is demonstrated and analysed for two standard detector types (NaI(Tl) and HPGe). The deviation display enhances positive significant changes while suppressing the natural background fluctuations. After an initialization time of about 10min this technique leads to a homogeneous display dominated by the background colour, where even small changes in spectral data are easy to discover. As this paper shows, the deviation display method works well for all tested gamma energies and natural background radiation levels and with both tested detector systems.

  16. A randomized controlled trial investigating the effects of craniosacral therapy on pain and heart rate variability in fibromyalgia patients.

    PubMed

    Castro-Sánchez, Adelaida María; Matarán-Peñarrocha, Guillermo A; Sánchez-Labraca, Nuria; Quesada-Rubio, José Manuel; Granero-Molina, José; Moreno-Lorenzo, Carmen

    2011-01-01

    Fibromyalgia is a prevalent musculoskeletal disorder associated with widespread mechanical tenderness, fatigue, non-refreshing sleep, depressed mood and pervasive dysfunction of the autonomic nervous system: tachycardia, postural intolerance, Raynaud's phenomenon and diarrhoea. To determine the effects of craniosacral therapy on sensitive tender points and heart rate variability in patients with fibromyalgia. A randomized controlled trial. Ninety-two patients with fibromyalgia were randomly assigned to an intervention group or placebo group. Patients received treatments for 20 weeks. The intervention group underwent a craniosacral therapy protocol and the placebo group received sham treatment with disconnected magnetotherapy equipment. Pain intensity levels were determined by evaluating tender points, and heart rate variability was recorded by 24-hour Holter monitoring. After 20 weeks of treatment, the intervention group showed significant reduction in pain at 13 of the 18 tender points (P < 0.05). Significant differences in temporal standard deviation of RR segments, root mean square deviation of temporal standard deviation of RR segments and clinical global impression of improvement versus baseline values were observed in the intervention group but not in the placebo group. At two months and one year post therapy, the intervention group showed significant differences versus baseline in tender points at left occiput, left-side lower cervical, left epicondyle and left greater trochanter and significant differences in temporal standard deviation of RR segments, root mean square deviation of temporal standard deviation of RR segments and clinical global impression of improvement. Craniosacral therapy improved medium-term pain symptoms in patients with fibromyalgia.

  17. 41 CFR 102-38.30 - How does an executive agency request a deviation from the provisions of this part?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... which are distinct from the standard deviation process and specific to the requirements of the Federal... agency request a deviation from the provisions of this part? 102-38.30 Section 102-38.30 Public Contracts... executive agency request a deviation from the provisions of this part? Refer to §§ 102-2.60 through 102-2...

  18. Normalizing and scaling of data to derive human response corridors from impact tests.

    PubMed

    Yoganandan, Narayan; Arun, Mike W J; Pintar, Frank A

    2014-06-03

    It is well known that variability is inherent in any biological experiment. Human cadavers (Post-Mortem Human Subjects, PMHS) are routinely used to determine responses to impact loading for crashworthiness applications including civilian (motor vehicle) and military environments. It is important to transform measured variables from PMHS tests (accelerations, forces and deflections) to a standard or reference population, termed normalization. The transformation process should account for inter-specimen variations with some underlying assumptions used during normalization. Scaling is a process by which normalized responses are converted from one standard to another (example, mid-size adult male to large-male and small-size female adults, and to pediatric populations). These responses are used to derive corridors to assess the biofidelity of anthropomorphic test devices (crash dummies) used to predict injury in impact environments and design injury mitigating devices. This survey examines the pros and cons of different approaches for obtaining normalized and scaled responses and corridors used in biomechanical studies for over four decades. Specifically, the equal-stress equal-velocity and impulse-momentum methods along with their variations are discussed in this review. Methods ranging from subjective to quasi-static loading to different approaches are discussed for deriving temporal mean and plus minus one standard deviation human corridors of time-varying fundamental responses and cross variables (e.g., force-deflection). The survey offers some insights into the potential efficacy of these approaches with examples from recent impact tests and concludes with recommendations for future studies. The importance of considering various parameters during the experimental design of human impact tests is stressed. Published by Elsevier Ltd.

  19. Family structure and childhood anthropometry in Saint Paul, Minnesota in 1918

    PubMed Central

    Warren, John Robert

    2017-01-01

    Concern with childhood nutrition prompted numerous surveys of children’s growth in the United States after 1870. The Children’s Bureau’s 1918 “Weighing and Measuring Test” measured two million children to produce the first official American growth norms. Individual data for 14,000 children survives from the Saint Paul, Minnesota survey whose stature closely approximated national norms. As well as anthropometry the survey recorded exact ages, street address and full name. These variables allow linkage to the 1920 census to obtain demographic and socioeconomic information. We matched 72% of children to census families creating a sample of nearly 10,000 children. Children in the entire survey (linked set) averaged 0.74 (0.72) standard deviations below modern WHO height-for-age standards, and 0.48 (0.46) standard deviations below modern weight-for-age norms. Sibship size strongly influenced height-for-age, and had weaker influence on weight-for-age. Each additional child six or underreduced height-for-age scores by 0.07 standard deviations (95% CI: −0.03, 0.11). Teenage siblings had little effect on height-forage. Social class effects were substantial. Children of laborers averaged half a standard deviation shorter than children of professionals. Family structure and socio-economic status had compounding impacts on children’s stature. PMID:28943749

  20. The Effect of Changing Scan Mode on Trabecular Bone Score Using Lunar Prodigy.

    PubMed

    Chen, Weiwen; Slattery, Anthony; Center, Jacqueline; Pocock, Nicholas

    2016-10-01

    Trabecular bone score (TBS) is a measure of gray scale homogeneity that correlates with trabecular microarchitecture and is an independent predictor of fracture risk. TBS is being increasingly used in the assessment of patients at risk of osteoporosis and has recently been incorporated into FRAX ® . GE Lunar machines acquire spine scans using 1 of 3 acquisition modes depending on abdominal tissue thickness (thin, standard, and thick). From a database review, 30 patients (mean body mass index: 30.8, range 26.2-34.1) were identified who had undergone lumbar spine DXA scans (GE Lunar Prodigy, software 14.10; Lunar Radiation Corporation, Madison, WI) in both standard mode and thick mode, on the same day with no repositioning. Lumbar spine bone mineral density (L1-L4) and TBS were derived from the 30 paired spine scans. There was no significant difference in lumbar spine bone mineral density between the 2 scanning modes. There were, however, significant higher TBS values from the spine scans acquired in thick mode compared to the TBS values derived from spine acquisitions in standard mode (mean TBS difference: 0.24 [20%], standard deviation ±0.10). In conclusion, these preliminary data suggest that TBS values acquired in the GE Lunar Prodigy are dependent on the scanning mode used. Further evaluation is required to confirm the cause and develop appropriate protocols. Copyright © 2016 International Society for Clinical Densitometry. Published by Elsevier Inc. All rights reserved.

  1. Models of Lift and Drag Coefficients of Stalled and Unstalled Airfoils in Wind Turbines and Wind Tunnels

    NASA Technical Reports Server (NTRS)

    Spera, David A.

    2008-01-01

    Equations are developed with which to calculate lift and drag coefficients along the spans of torsionally-stiff rotating airfoils of the type used in wind turbine rotors and wind tunnel fans, at angles of attack in both the unstalled and stalled aerodynamic regimes. Explicit adjustments are made for the effects of aspect ratio (length to chord width) and airfoil thickness ratio. Calculated lift and drag parameters are compared to measured parameters for 55 airfoil data sets including 585 test points. Mean deviation was found to be -0.4 percent and standard deviation was 4.8 percent. When the proposed equations were applied to the calculation of power from a stall-controlled wind turbine tested in a NASA wind tunnel, mean deviation from 54 data points was -1.3 percent and standard deviation was 4.0 percent. Pressure-rise calculations for a large wind tunnel fan deviated by 2.7 percent (mean) and 4.4 percent (standard). The assumption that a single set of lift and drag coefficient equations can represent the stalled aerodynamic behavior of a wide variety of airfoils was found to be satisfactory.

  2. Comparison of active-set method deconvolution and matched-filtering for derivation of an ultrasound transit time spectrum.

    PubMed

    Wille, M-L; Zapf, M; Ruiter, N V; Gemmeke, H; Langton, C M

    2015-06-21

    The quality of ultrasound computed tomography imaging is primarily determined by the accuracy of ultrasound transit time measurement. A major problem in analysis is the overlap of signals making it difficult to detect the correct transit time. The current standard is to apply a matched-filtering approach to the input and output signals. This study compares the matched-filtering technique with active set deconvolution to derive a transit time spectrum from a coded excitation chirp signal and the measured output signal. The ultrasound wave travels in a direct and a reflected path to the receiver, resulting in an overlap in the recorded output signal. The matched-filtering and deconvolution techniques were applied to determine the transit times associated with the two signal paths. Both techniques were able to detect the two different transit times; while matched-filtering has a better accuracy (0.13 μs versus 0.18 μs standard deviations), deconvolution has a 3.5 times improved side-lobe to main-lobe ratio. A higher side-lobe suppression is important to further improve image fidelity. These results suggest that a future combination of both techniques would provide improved signal detection and hence improved image fidelity.

  3. Spatiotemporal Parameters are not Substantially Influenced by Load Carriage or Inclination During Treadmill and Overground Walking

    PubMed Central

    Seay, Joseph F.; Gregorczyk, Karen N.; Hasselquist, Leif

    2016-01-01

    Abstract Influences of load carriage and inclination on spatiotemporal parameters were examined during treadmill and overground walking. Ten soldiers walked on a treadmill and overground with three load conditions (00 kg, 20 kg, 40 kg) during level, uphill (6% grade) and downhill (-6% grade) inclinations at self-selected speed, which was constant across conditions. Mean values and standard deviations for double support percentage, stride length and a step rate were compared across conditions. Double support percentage increased with load and inclination change from uphill to level walking, with a 0.4% stance greater increase at the 20 kg condition compared to 00 kg. As inclination changed from uphill to downhill, the step rate increased more overground (4.3 ± 3.5 steps/min) than during treadmill walking (1.7 ± 2.3 steps/min). For the 40 kg condition, the standard deviations were larger than the 00 kg condition for both the step rate and double support percentage. There was no change between modes for step rate standard deviation. For overground compared to treadmill walking, standard deviation for stride length and double support percentage increased and decreased, respectively. Changes in the load of up to 40 kg, inclination of 6% grade away from the level (i.e., uphill or downhill) and mode (treadmill and overground) produced small, yet statistically significant changes in spatiotemporal parameters. Variability, as assessed by standard deviation, was not systematically lower during treadmill walking compared to overground walking. Due to the small magnitude of changes, treadmill walking appears to replicate the spatiotemporal parameters of overground walking. PMID:28149338

  4. The two errors of using the within-subject standard deviation (WSD) as the standard error of a reliable change index.

    PubMed

    Maassen, Gerard H

    2010-08-01

    In this Journal, Lewis and colleagues introduced a new Reliable Change Index (RCI(WSD)), which incorporated the within-subject standard deviation (WSD) of a repeated measurement design as the standard error. In this note, two opposite errors in using WSD this way are demonstrated. First, being the standard error of measurement of only a single assessment makes WSD too small when practice effects are absent. Then, too many individuals will be designated reliably changed. Second, WSD can grow unlimitedly to the extent that differential practice effects occur. This can even make RCI(WSD) unable to detect any reliable change.

  5. Minimization of deviations of gear real tooth surfaces determined by coordinate measurements

    NASA Technical Reports Server (NTRS)

    Litvin, F. L.; Kuan, C.; Wang, J.-C.; Handschuh, R. F.; Masseth, J.; Maruyama, N.

    1992-01-01

    The deviations of a gear's real tooth surface from the theoretical surface are determined by coordinate measurements at the grid of the surface. A method was developed to transform the deviations from Cartesian coordinates to those along the normal at the measurement locations. Equations are derived that relate the first order deviations with the adjustment to the manufacturing machine-tool settings. The deviations of the entire surface are minimized. The minimization is achieved by application of the least-square method for an overdetermined system of linear equations. The proposed method is illustrated with a numerical example for hypoid gear and pinion.

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    McIntosh, Gordon; Indermuehle, Balthasar, E-mail: mcintogc@morris.umn.edu, E-mail: balt.indermuehle@csiro.au

    We present an analysis of velocity parameters derived from multi-epoch observations of the SiO maser spectra of 47 long period variables (LPVs). The velocity parameters are important to inform and constrain theoretical models of SiO maser emission and to extract information on binary orbits. Mira and R Aquarii (R Aqr) are two known binaries included in the program. The 47 LPVs are among 121 sources of the Australia Telescope National Facility Mopra telescope's monitoring program. Observations were carried out several times a year between 2008 and 2012 and are continuing. The SiO spectra are from the v = 1, Jmore » = 1-0 (43.122 GHz; hereafter J10) and the v = 1, J = 2-1 (86.2434 GHz; hereafter J21) transitions. For 41 of the 47 LPVs we observed both transitions nearly simultaneously in 457 observations. We have determined and compared the velocity centroids (VCs) and velocity ranges (VRs) of emission suffixed as above (10 and 21) for the two transitions: VC10, VC21, VR10, and VR21. The VCs of the two transitions are, on average, within 0.13 km s{sup -1} of each other but are sometimes separated by a few km s{sup -1}. The VC10s are, on average, slightly more positive than the VC21s. The values of the VCs in the two transitions have been compared to justify using both of these transitions to extract binary star orbital parameters. The arithmetic mean VR10 derived from 635 observations of 47 sources is 6.4 km s{sup -1} with a standard deviation of 3.4 km s{sup -1}, while the mean VR21 derived from 485 observations of 41 sources is 4.2 km s{sup -1} with a standard deviation of 2.8 km s{sup -1}. The number of occurrences of VR10 and VR21 versus VR have different distributions. The differences in the VRs indicate that the J21 and J10 emissions arise from dynamically different regions of the circumstellar environment.« less

  7. A short note on the inclusion of sultriness issues in perceived temperature in mild climates

    NASA Astrophysics Data System (ADS)

    Staiger, Henning; Laschewski, Gudrun; Matzarakis, Andreas

    2018-01-01

    Sultriness is a specific case in thermal perception under warm/humid environments and frequently applied in German operational weather forecast and is assumed if the dew-point temperature t d exceeds a threshold of 16.5 °C. In perceived temperature ( PT), which is based on the ASHRAE two-node-model, a Central European climatology was prepared of the classical predicted mean vote ( PMV), exclusively linked to thermal stress, and the so-called rational PMV* that additionally accounts for the humidity in the meteorological environment and is closely linked to thermal strain. The standard deviation of the difference Δ PMV = PMV* - PMV over PMV reveals a similarity to the appearance of sultriness that suggests as side effect of the PT parameterisation a thermophysiologically based definition of sultriness: "Under warm/humid conditions a subject adapted to mild climatologic conditions perceives sultriness if the actual value of Δ PMV exceeds the long-term mean by more than its single standard deviation". This definition accounts for all environmental and subject related variables influencing the thermal state of the body and is in accordance with all in the literature described properties in the perception of sultriness. The two definitions coincide more or less at daylight hours for t d values markedly beyond the threshold. However, in the t d threshold region, the PT-derived definition offers stronger differentiated patterns and is significantly less frequent at nighttime than the mono-causal definition. For given PT values, the sensible heat flux via the skin shows an increase under a sultry environment, whereas the latent is reduced; skin and core temperatures as well as the skin blood flow are also less. In any case, PT-derived sultriness is linked with an increased thermal strain on the body temperatures, which is a measure of discomfort caused by increased humidity and/or dissatisfaction with the thermal environment. This confirms the thermal uncomfortable feeling accompanying the perception of sultriness. Therefore, the PT-derived sultriness can be presumed to be a more appropriate measure for the perception of sultriness, because it accounts for all environmental impacts on thermoregulation.

  8. Anomalous Diffusion Measured by a Twice-Refocused Spin Echo Pulse Sequence: Analysis Using Fractional Order Calculus

    PubMed Central

    2011-01-01

    Purpose To theoretically develop and experimentally validate a formulism based on a fractional order calculus (FC) diffusion model to characterize anomalous diffusion in brain tissues measured with a twice-refocused spin-echo (TRSE) pulse sequence. Materials and Methods The FC diffusion model is the fractional order generalization of the Bloch-Torrey equation. Using this model, an analytical expression was derived to describe the diffusion-induced signal attenuation in a TRSE pulse sequence. To experimentally validate this expression, a set of diffusion-weighted (DW) images was acquired at 3 Tesla from healthy human brains using a TRSE sequence with twelve b-values ranging from 0 to 2,600 s/mm2. For comparison, DW images were also acquired using a Stejskal-Tanner diffusion gradient in a single-shot spin-echo echo planar sequence. For both datasets, a Levenberg-Marquardt fitting algorithm was used to extract three parameters: diffusion coefficient D, fractional order derivative in space β, and a spatial parameter μ (in units of μm). Using adjusted R-squared values and standard deviations, D, β and μ values and the goodness-of-fit in three specific regions of interest (ROI) in white matter, gray matter, and cerebrospinal fluid were evaluated for each of the two datasets. In addition, spatially resolved parametric maps were assessed qualitatively. Results The analytical expression for the TRSE sequence, derived from the FC diffusion model, accurately characterized the diffusion-induced signal loss in brain tissues at high b-values. In the selected ROIs, the goodness-of-fit and standard deviations for the TRSE dataset were comparable with the results obtained from the Stejskal-Tanner dataset, demonstrating the robustness of the FC model across multiple data acquisition strategies. Qualitatively, the D, β, and μ maps from the TRSE dataset exhibited fewer artifacts, reflecting the improved immunity to eddy currents. Conclusion The diffusion-induced signal attenuation in a TRSE pulse sequence can be described by an FC diffusion model at high b-values. This model performs equally well for data acquired from the human brain tissues with a TRSE pulse sequence or a conventional Stejskal-Tanner sequence. PMID:21509877

  9. Anomalous diffusion measured by a twice-refocused spin echo pulse sequence: analysis using fractional order calculus.

    PubMed

    Gao, Qing; Srinivasan, Girish; Magin, Richard L; Zhou, Xiaohong Joe

    2011-05-01

    To theoretically develop and experimentally validate a formulism based on a fractional order calculus (FC) diffusion model to characterize anomalous diffusion in brain tissues measured with a twice-refocused spin-echo (TRSE) pulse sequence. The FC diffusion model is the fractional order generalization of the Bloch-Torrey equation. Using this model, an analytical expression was derived to describe the diffusion-induced signal attenuation in a TRSE pulse sequence. To experimentally validate this expression, a set of diffusion-weighted (DW) images was acquired at 3 Tesla from healthy human brains using a TRSE sequence with twelve b-values ranging from 0 to 2600 s/mm(2). For comparison, DW images were also acquired using a Stejskal-Tanner diffusion gradient in a single-shot spin-echo echo planar sequence. For both datasets, a Levenberg-Marquardt fitting algorithm was used to extract three parameters: diffusion coefficient D, fractional order derivative in space β, and a spatial parameter μ (in units of μm). Using adjusted R-squared values and standard deviations, D, β, and μ values and the goodness-of-fit in three specific regions of interest (ROIs) in white matter, gray matter, and cerebrospinal fluid, respectively, were evaluated for each of the two datasets. In addition, spatially resolved parametric maps were assessed qualitatively. The analytical expression for the TRSE sequence, derived from the FC diffusion model, accurately characterized the diffusion-induced signal loss in brain tissues at high b-values. In the selected ROIs, the goodness-of-fit and standard deviations for the TRSE dataset were comparable with the results obtained from the Stejskal-Tanner dataset, demonstrating the robustness of the FC model across multiple data acquisition strategies. Qualitatively, the D, β, and μ maps from the TRSE dataset exhibited fewer artifacts, reflecting the improved immunity to eddy currents. The diffusion-induced signal attenuation in a TRSE pulse sequence can be described by an FC diffusion model at high b-values. This model performs equally well for data acquired from the human brain tissues with a TRSE pulse sequence or a conventional Stejskal-Tanner sequence. Copyright © 2011 Wiley-Liss, Inc.

  10. Gender Differences in Numeracy in Indonesia: Evidence from a Longitudinal Dataset

    ERIC Educational Resources Information Center

    Suryadarma, Daniel

    2015-01-01

    This paper uses a rich longitudinal dataset to measure the evolution of the gender differences in numeracy among school-age children in Indonesia. Girls outperformed boys by 0.08 standard deviations when the sample was around 11 years old. Seven years later, the gap has widened to 0.19 standard deviations, equivalent to around 18 months of…

  11. A Survey Data Response to the Teaching of Utility Curves and Risk Aversion

    ERIC Educational Resources Information Center

    Hobbs, Jeffrey; Sharma, Vivek

    2011-01-01

    In many finance and economics courses as well as in practice, the concept of risk aversion is reduced to the standard deviation of returns, whereby risk-averse investors prefer to minimize their portfolios' standard deviations. In reality, the concept of risk aversion is richer and more interesting than this, and can easily be conveyed through…

  12. On the Linear Relation between the Mean and the Standard Deviation of a Response Time Distribution

    ERIC Educational Resources Information Center

    Wagenmakers, Eric-Jan; Brown, Scott

    2007-01-01

    Although it is generally accepted that the spread of a response time (RT) distribution increases with the mean, the precise nature of this relation remains relatively unexplored. The authors show that in several descriptive RT distributions, the standard deviation increases linearly with the mean. Results from a wide range of tasks from different…

  13. A novel sorbent based on carbon nanotube/amino-functionalized sol-gel for the headspace solid-phase microextraction of α-bisabolol from medicinal plant samples using experimental design.

    PubMed

    Yarazavi, Mina; Noroozian, Ebrahim

    2018-02-13

    A novel sol-gel coating on a stainless-steel fiber was developed for the first time for the headspace solid-phase microextraction and determination of α-bisabolol with gas chromatography and flame ionization detection. The parameters influencing the efficiency of solid-phase microextraction process, such as extraction time and temperature, pH, and ionic strength, were optimized by the experimental design method. Under optimized conditions, the linear range was between 0.0027 and 100 μg/mL. The relative standard deviations determined at 0.01 and 1.0 μg/mL concentration levels (n = 3), respectively, were as follows: intraday relative standard deviations 3.4 and 3.3%; interday relative standard deviations 5.0 and 4.3%; and fiber-to-fiber relative standard deviations 6.0 and 3.5%. The relative recovery values were 90.3 and 101.4% at 0.01 and 1.0 μg/mL spiking levels, respectively. The proposed method was successfully applied to various real samples containing α-bisabolol. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Results of an interlaboratory method performance study for the size determination and quantification of silver nanoparticles in chicken meat by single-particle inductively coupled plasma mass spectrometry (sp-ICP-MS).

    PubMed

    Weigel, Stefan; Peters, Ruud; Loeschner, Katrin; Grombe, Ringo; Linsinger, Thomas P J

    2017-08-01

    Single-particle inductively coupled plasma mass spectrometry (sp-ICP-MS) promises fast and selective determination of nanoparticle size and number concentrations. While several studies on practical applications have been published, data on formal, especially interlaboratory validation of sp-ICP-MS, is sparse. An international interlaboratory study was organized to determine repeatability and reproducibility of the determination of the median particle size and particle number concentration of Ag nanoparticles (AgNPs) in chicken meat. Ten laboratories from the European Union, the USA, and Canada determined particle size and particle number concentration of two chicken meat homogenates spiked with polyvinylpyrrolidone (PVP)-stabilized AgNPs. For the determination of the median particle diameter, repeatability standard deviations of 2 and 5% were determined, and reproducibility standard deviations were 15 and 25%, respectively. The equivalent median diameter itself was approximately 60% larger than the diameter of the particles in the spiking solution. Determination of the particle number concentration was significantly less precise, with repeatability standard deviations of 7 and 18% and reproducibility standard deviations of 70 and 90%.

  15. Estimation of Tooth Size Discrepancies among Different Malocclusion Groups

    PubMed Central

    Bala, Madhu; Goyal, Virender

    2014-01-01

    ABSTRACT Regards and Tribute: Late Dr Narender Hasija was a mentor and visionary in the light of knowledge and experience. We pay our regards with deepest gratitude to the departed soul to rest in peace. Bolton’s ratios help in estimating overbite, overjet relationships, the effects of contemplated extractions on posterior occlusion, incisor relationships and identification of occlusal misfit produced by tooth size discrepancies. Aim: To determine any difference in tooth size discrepancy in anterior as well as overall ratio in different malocclusions and comparison with Bolton’s study. Materials and methods: After measuring the teeth on all 100 patients, Bolton’s analysis was performed. Results were compared with Bolton’s means and standard deviations. The results were also subjected to statistical analysis. Results show that the mean and standard deviations of ideal occlusion cases are comparable with those Bolton but, when the mean and standard deviation of malocclusion groups are compared with those of Bolton, the values of standard deviation are higher, though the mean is comparable. How to cite this article: Hasija N, Bala M, Goyal V. Estimation of Tooth Size Discrepancies among Different Malocclusion Groups. Int J Clin Pediatr Dent 2014;7(2):82-85. PMID:25356005

  16. On-line high-performance liquid chromatography-ultraviolet-nuclear magnetic resonance method of the markers of nerve agents for verification of the Chemical Weapons Convention.

    PubMed

    Mazumder, Avik; Gupta, Hemendra K; Garg, Prabhat; Jain, Rajeev; Dubey, Devendra K

    2009-07-03

    This paper details an on-flow liquid chromatography-ultraviolet-nuclear magnetic resonance (LC-UV-NMR) method for the retrospective detection and identification of alkyl alkylphosphonic acids (AAPAs) and alkylphosphonic acids (APAs), the markers of the toxic nerve agents for verification of the Chemical Weapons Convention (CWC). Initially, the LC-UV-NMR parameters were optimized for benzyl derivatives of the APAs and AAPAs. The optimized parameters include stationary phase C(18), mobile phase methanol:water 78:22 (v/v), UV detection at 268nm and (1)H NMR acquisition conditions. The protocol described herein allowed the detection of analytes through acquisition of high quality NMR spectra from the aqueous solution of the APAs and AAPAs with high concentrations of interfering background chemicals which have been removed by preceding sample preparation. The reported standard deviation for the quantification is related to the UV detector which showed relative standard deviations (RSDs) for quantification within +/-1.1%, while lower limit of detection upto 16mug (in mug absolute) for the NMR detector. Finally the developed LC-UV-NMR method was applied to identify the APAs and AAPAs in real water samples, consequent to solid phase extraction and derivatization. The method is fast (total experiment time approximately 2h), sensitive, rugged and efficient.

  17. Robust optimization of the billet for isothermal local loading transitional region of a Ti-alloy rib-web component based on dual-response surface method

    NASA Astrophysics Data System (ADS)

    Wei, Ke; Fan, Xiaoguang; Zhan, Mei; Meng, Miao

    2018-03-01

    Billet optimization can greatly improve the forming quality of the transitional region in the isothermal local loading forming (ILLF) of large-scale Ti-alloy ribweb components. However, the final quality of the transitional region may be deteriorated by uncontrollable factors, such as the manufacturing tolerance of the preforming billet, fluctuation of the stroke length, and friction factor. Thus, a dual-response surface method (RSM)-based robust optimization of the billet was proposed to address the uncontrollable factors in transitional region of the ILLF. Given that the die underfilling and folding defect are two key factors that influence the forming quality of the transitional region, minimizing the mean and standard deviation of the die underfilling rate and avoiding folding defect were defined as the objective function and constraint condition in robust optimization. Then, the cross array design was constructed, a dual-RSM model was established for the mean and standard deviation of the die underfilling rate by considering the size parameters of the billet and uncontrollable factors. Subsequently, an optimum solution was derived to achieve the robust optimization of the billet. A case study on robust optimization was conducted. Good results were attained for improving the die filling and avoiding folding defect, suggesting that the robust optimization of the billet in the transitional region of the ILLF was efficient and reliable.

  18. Spectral relative standard deviation: a practical benchmark in metabolomics.

    PubMed

    Parsons, Helen M; Ekman, Drew R; Collette, Timothy W; Viant, Mark R

    2009-03-01

    Metabolomics datasets, by definition, comprise of measurements of large numbers of metabolites. Both technical (analytical) and biological factors will induce variation within these measurements that is not consistent across all metabolites. Consequently, criteria are required to assess the reproducibility of metabolomics datasets that are derived from all the detected metabolites. Here we calculate spectrum-wide relative standard deviations (RSDs; also termed coefficient of variation, CV) for ten metabolomics datasets, spanning a variety of sample types from mammals, fish, invertebrates and a cell line, and display them succinctly as boxplots. We demonstrate multiple applications of spectral RSDs for characterising technical as well as inter-individual biological variation: for optimising metabolite extractions, comparing analytical techniques, investigating matrix effects, and comparing biofluids and tissue extracts from single and multiple species for optimising experimental design. Technical variation within metabolomics datasets, recorded using one- and two-dimensional NMR and mass spectrometry, ranges from 1.6 to 20.6% (reported as the median spectral RSD). Inter-individual biological variation is typically larger, ranging from as low as 7.2% for tissue extracts from laboratory-housed rats to 58.4% for fish plasma. In addition, for some of the datasets we confirm that the spectral RSD values are largely invariant across different spectral processing methods, such as baseline correction, normalisation and binning resolution. In conclusion, we propose spectral RSDs and their median values contained herein as practical benchmarks for metabolomics studies.

  19. Ion pair-based dispersive liquid-liquid microextraction followed by high performance liquid chromatography as a new method for determining five folate derivatives in foodstuffs.

    PubMed

    Nojavan, Yones; Kamankesh, Marzieh; Shahraz, Farzaneh; Hashemi, Maryam; Mohammadi, Abdorreza

    2015-05-01

    A novel technique for simultaneous determination of five folate derivatives in various food matrices was developed by ion pair-based dispersive liquid-liquid microextraction (IP-DLLME) combined with high-performance liquid chromatography (HPLC). In the proposed method, N-methyl-N,N-dioctyloctan-1-ammonium chloride (aliquat-336) was used as an ion-pair reagent. Effective variables of microextraction process were optimized. Under optimum conditions, the method yielded a linear calibration curve ranging from 1-200 ng g(-1) with correlation coefficients (r(2)) higher than 0.98. The relative standard deviation for the seven analyses was 5.2-7.4%. Enrichment factors for the five folates ranged between 108-135. Limits of detection were 2-4.1 ng g(-1). A comparison of this method with other methods described that the new proposed method is rapid and accurate, and gives very good enrichment factors and detection limits for determining five folate derivatives. The newly developed method was successfully applied for the determination of five folate derivatives in wheat flour, egg yolk and orange juice samples. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Inversion of ground-motion data from a seismometer array for rotation using a modification of Jaeger's method

    USGS Publications Warehouse

    Chi, Wu-Cheng; Lee, W.H.K.; Aston, J.A.D.; Lin, C.J.; Liu, C.-C.

    2011-01-01

    We develop a new way to invert 2D translational waveforms using Jaeger's (1969) formula to derive rotational ground motions about one axis and estimate the errors in them using techniques from statistical multivariate analysis. This procedure can be used to derive rotational ground motions and strains using arrayed translational data, thus providing an efficient way to calibrate the performance of rotational sensors. This approach does not require a priori information about the noise level of the translational data and elastic properties of the media. This new procedure also provides estimates of the standard deviations of the derived rotations and strains. In this study, we validated this code using synthetic translational waveforms from a seismic array. The results after the inversion of the synthetics for rotations were almost identical with the results derived using a well-tested inversion procedure by Spudich and Fletcher (2009). This new 2D procedure can be applied three times to obtain the full, three-component rotations. Additional modifications can be implemented to the code in the future to study different features of the rotational ground motions and strains induced by the passage of seismic waves.

  1. Development and operation of a quality assurance system for deviations from standard operating procedures in a clinical cell therapy laboratory.

    PubMed

    McKenna, D; Kadidlo, D; Sumstad, D; McCullough, J

    2003-01-01

    Errors and accidents, or deviations from standard operating procedures, other policy, or regulations must be documented and reviewed, with corrective actions taken to assure quality performance in a cellular therapy laboratory. Though expectations and guidance for deviation management exist, a description of the framework for the development of such a program is lacking in the literature. Here we describe our deviation management program, which uses a Microsoft Access database and Microsoft Excel to analyze deviations and notable events, facilitating quality assurance (QA) functions and ongoing process improvement. Data is stored in a Microsoft Access database with an assignment to one of six deviation type categories. Deviation events are evaluated for potential impact on patient and product, and impact scores for each are determined using a 0- 4 grading scale. An immediate investigation occurs, and corrective actions are taken to prevent future similar events from taking place. Additionally, deviation data is collectively analyzed on a quarterly basis using Microsoft Excel, to identify recurring events or developing trends. Between January 1, 2001 and December 31, 2001 over 2500 products were processed at our laboratory. During this time period, 335 deviations and notable events occurred, affecting 385 products and/or patients. Deviations within the 'technical error' category were most common (37%). Thirteen percent of deviations had a patient and/or a product impact score > or = 2, a score indicating, at a minimum, potentially affected patient outcome or moderate effect upon product quality. Real-time analysis and quarterly review of deviations using our deviation management program allows for identification and correction of deviations. Monitoring of deviation trends allows for process improvement and overall successful functioning of the QA program in the cell therapy laboratory. Our deviation management program could serve as a model for other laboratories in need of such a program.

  2. A numerical model for water and heat transport in freezing soils with nonequilibrium ice-water interfaces

    NASA Astrophysics Data System (ADS)

    Peng, Zhenyang; Tian, Fuqiang; Wu, Jingwei; Huang, Jiesheng; Hu, Hongchang; Darnault, Christophe J. G.

    2016-09-01

    A one-dimensional numerical model of heat and water transport in freezing soils is developed by assuming that ice-water interfaces are not necessarily in equilibrium. The Clapeyron equation, which is derived from a static ice-water interface using the thermal equilibrium theory, cannot be readily applied to a dynamic system, such as freezing soils. Therefore, we handled the redistribution of liquid water with the Richard's equation. In this application, the sink term is replaced by the freezing rate of pore water, which is proportional to the extent of supercooling and available water content for freezing by a coefficient, β. Three short-term laboratory column simulations show reasonable agreement with observations, with standard error of simulation on water content ranging between 0.007 and 0.011 cm3 cm-3, showing improved accuracy over other models that assume equilibrium ice-water interfaces. Simulation results suggest that when the freezing front is fixed at a specific depth, deviation of the ice-water interface from equilibrium, at this location, will increase with time. However, this deviation tends to weaken when the freezing front slowly penetrates to a greater depth, accompanied with thinner soils of significant deviation. The coefficient, β, plays an important role in the simulation of heat and water transport. A smaller β results in a larger deviation in the ice-water interface from equilibrium, and backward estimation of the freezing front. It also leads to an underestimation of water content in soils that were previously frozen by a rapid freezing rate, and an overestimation of water content in the rest of the soils.

  3. Ku-band radar threshold analysis

    NASA Technical Reports Server (NTRS)

    Weber, C. L.; Polydoros, A.

    1979-01-01

    The statistics of the CFAR threshold for the Ku-band radar was determined. Exact analytical results were developed for both the mean and standard deviations in the designated search mode. The mean value is compared to the results of a previously reported simulation. The analytical results are more optimistic than the simulation results, for which no explanation is offered. The normalized standard deviation is shown to be very sensitive to signal-to-noise ratio and very insensitive to the noise correlation present in the range gates of the designated search mode. The substantial variation in the CFAR threshold is dominant at large values of SNR where the normalized standard deviation is greater than 0.3. Whether or not this significantly affects the resulting probability of detection is a matter which deserves additional attention.

  4. Standard deviation analysis of the mastoid fossa temperature differential reading: a potential model for objective chiropractic assessment.

    PubMed

    Hart, John

    2011-03-01

    This study describes a model for statistically analyzing follow-up numeric-based chiropractic spinal assessments for an individual patient based on his or her own baseline. Ten mastoid fossa temperature differential readings (MFTD) obtained from a chiropractic patient were used in the study. The first eight readings served as baseline and were compared to post-adjustment readings. One of the two post-adjustment MFTD readings fell outside two standard deviations of the baseline mean and therefore theoretically represents improvement according to pattern analysis theory. This study showed how standard deviation analysis may be used to identify future outliers for an individual patient based on his or her own baseline data. Copyright © 2011 National University of Health Sciences. Published by Elsevier Inc. All rights reserved.

  5. Effects of Random Shadings, Phasing Errors, and Element Failures on the Beam Patterns of Linear and Planar Arrays

    DTIC Science & Technology

    1980-03-14

    failure Sigmar (Or) in line 50, the standard deviation of the relative error of the weights Sigmap (o) in line 60, the standard deviation of the phase...200, the weight structures in the x and y coordinates Q in line 210, the probability of element failure Sigmar (Or) in line 220, the standard...NUMBER OF ELEMENTS =u;2*H 120 PRINT "Pr’obability of elemenit failure al;O 130 PRINT "Standard dtvi&t ion’ oe r.1&tive ýrror of wl; Sigmar 14 0 PRINT

  6. SU-E-I-59: Investigation of the Usefulness of a Standard Deviation and Mammary Gland Density as Indexes for Mammogram Classification.

    PubMed

    Takarabe, S; Yabuuchi, H; Morishita, J

    2012-06-01

    To investigate the usefulness of the standard deviation of pixel values in a whole mammary glands region and the percentage of a high- density mammary glands region to a whole mammary glands region as features for classification of mammograms into four categories based on the ACR BI-RADS breast composition. We used 36 digital mediolateral oblique view mammograms (18 patients) approved by our IRB. These images were classified into the four categories of breast compositions by an experienced breast radiologist and the results of the classification were regarded as a gold standard. First, a whole mammary region in a breast was divided into two regions such as a high-density mammary glands region and a low/iso-density mammary glands region by using a threshold value that was obtained from the pixel values corresponding to a pectoral muscle region. Then the percentage of a high-density mammary glands region to a whole mammary glands region was calculated. In addition, as a new method, the standard deviation of pixel values in a whole mammary glands region was calculated as an index based on the intermingling of mammary glands and fats. Finally, all mammograms were classified by using the combination of the percentage of a high-density mammary glands region and the standard deviation of each image. The agreement rates of the classification between our proposed method and gold standard was 86% (31/36). This result signified that our method has the potential to classify mammograms. The combination of the standard deviation of pixel values in a whole mammary glands region and the percentage of a high-density mammary glands region to a whole mammary glands region was available as features to classify mammograms based on the ACR BI- RADS breast composition. © 2012 American Association of Physicists in Medicine.

  7. 40 CFR 63.7951 - What reports must I submit and when?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the information in § 63.10(d)(5)(i). (5) If there were no deviations from any emissions limitations... that there were no deviations from the emissions limitations, work practice standards, or operation and...) For each deviation from an emissions limitation (including an operating limit) that occurs at an...

  8. Solar coronal temperature diagnostics using emission line from multiple stages of ionization of iron

    NASA Technical Reports Server (NTRS)

    Brosius, Jeffrey W.; Davila, Joseph M.; Thomas, Roger J.; Thompson, William T.

    1994-01-01

    We obtained spatially resolved extreme-ultraviolet (EUV) spectra of AR 6615 on 1991 May 7 with NASA/ Goddard Space Flight Center's Solar EUV Rocket Telescope and Spectrograph (SERTS). Included are emission lines from four different stages of ionization of iron: Fe(+15) lambda 335 A, Fe(+14) lambda 327 A, Fe(+13) lambda 334 A, and Fe(+12) lambda 348 A. Using intensity ratios from among these lines, we have calculated the active region coronal temperature along the Solar Extreme Ultraviolet Telescope and Spectrograph (SERTS) slit. Temperatures derived from line ratios which incorporate adjacent stages of ionization are most sensitive to measurement uncertainties and yield the largest scatter. Temperatures derived from line ratios which incorporate nonadjacent stages of ionization are less sensitive to measurement uncertainties and yield little scatter. The active region temperature derived from these latter ratios has an average value of 2.54 x 10(exp 6) K, with a standard deviation approximately 0.12 x 10(exp 6) K, and shows no significant variation with position along the slit.

  9. 12C/13C isotopic ratios in red-giant stars of the open cluster NGC 6791

    NASA Astrophysics Data System (ADS)

    Szigeti, László; Mészáros, Szabolcs; Smith, Verne V.; Cunha, Katia; Lagarde, Nadège; Charbonnel, Corinne; García-Hernández, D. A.; Shetrone, Matthew; Pinsonneault, Marc; Allende Prieto, Carlos; Fernández-Trincado, J. G.; Kovács, József; Villanova, Sandro

    2018-03-01

    Carbon isotope ratios, along with carbon and nitrogen abundances, are derived in a sample of 11 red-giant members of one of the most metal-rich clusters in the Milky Way, NGC 6791. The selected red-giants have a mean metallicity and standard deviation of [Fe/H] = +0.39 ± 0.06 (Cunha et al. 2015). We used high-resolution H-band spectra obtained by the SDSS-IV Apache Point Observatory Galactic Evolution Experiment. The advantage of using high-resolution spectra in the H band is that lines of CO are well represented and their line profiles are sensitive to the variation of 12C/13C. Values of the 12C/13C ratio were obtained from a spectrum synthesis analysis. The derived 12C/13C ratios varied between 6.3 and 10.6 in NGC 6791, in agreement with the final isotopic ratios from thermohaline-induced mixing models. The ratios derived here are combined with those obtained for more metal poor red-giants from the literature to examine the correlation between 12C/13C, mass, metallicity, and evolutionary status.

  10. Scalar-tensor theories and modified gravity in the wake of GW170817

    NASA Astrophysics Data System (ADS)

    Langlois, David; Saito, Ryo; Yamauchi, Daisuke; Noui, Karim

    2018-03-01

    Theories of dark energy and modified gravity can be strongly constrained by astrophysical or cosmological observations, as illustrated by the recent observation of the gravitational wave event GW170817 and of its electromagnetic counterpart GRB 170817A, which showed that the speed of gravitational waves, cg , is the same as the speed of light, within deviations of order 10-15 . This observation implies severe restrictions on scalar-tensor theories, in particular theories whose action depends on second derivatives of a scalar field. Working in the very general framework of degenerate higher-order scalar-tensor (DHOST) theories, which encompass Horndeski and beyond Horndeski theories, we present the DHOST theories that satisfy cg=c . We then examine, for these theories, the screening mechanism that suppresses scalar interactions on small scales, namely the Vainshtein mechanism, and compute the corresponding gravitational laws for a nonrelativistic spherical body. We show that it can lead to a deviation from standard gravity inside matter, parametrized by three coefficients which satisfy a consistency relation and can be constrained by present and future astrophysical observations.

  11. MO-F-CAMPUS-T-03: Data Driven Approaches for Determination of Treatment Table Tolerance Values for Record and Verification Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gupta, N; DiCostanzo, D; Fullenkamp, M

    2015-06-15

    Purpose: To determine appropriate couch tolerance values for modern radiotherapy linac R&V systems with indexed patient setup. Methods: Treatment table tolerance values have been the most difficult to lower, due to many factors including variations in patient positioning and differences in table tops between machines. We recently installed nine linacs with similar tables and started indexing every patient in our clinic. In this study we queried our R&V database and analyzed the deviation of couch position values from the acquired values at verification simulation for all patients treated with indexed positioning. Mean and standard deviations of daily setup deviations weremore » computed in the longitudinal, lateral and vertical direction for 343 patient plans. The mean, median and standard error of the standard deviations across the whole patient population and for some disease sites were computed to determine tolerance values. Results: The plot of our couch deviation values showed a gaussian distribution, with some small deviations, corresponding to setup uncertainties on non-imaging days, and SRS/SRT/SBRT patients, as well as some large deviations which were spot checked and found to be corresponding to indexing errors that were overriden. Setting our tolerance values based on the median + 1 standard error resulted in tolerance values of 1cm lateral and longitudinal, and 0.5 cm vertical for all non- SRS/SRT/SBRT cases. Re-analizing the data, we found that about 92% of the treated fractions would be within these tolerance values (ignoring the mis-indexed patients). We also analyzed data for disease site based subpopulations and found no difference in the tolerance values that needed to be used. Conclusion: With the use of automation, auto-setup and other workflow efficiency tools being introduced into radiotherapy workflow, it is very essential to set table tolerances that allow safe treatments, but flag setup errors that need to be reassessed before treatments.« less

  12. Angular radiation models for Earth-atmosphere system. Volume 1: Shortwave radiation

    NASA Technical Reports Server (NTRS)

    Suttles, J. T.; Green, R. N.; Minnis, P.; Smith, G. L.; Staylor, W. F.; Wielicki, B. A.; Walker, I. J.; Young, D. F.; Taylor, V. R.; Stowe, L. L.

    1988-01-01

    Presented are shortwave angular radiation models which are required for analysis of satellite measurements of Earth radiation, such as those fro the Earth Radiation Budget Experiment (ERBE). The models consist of both bidirectional and directional parameters. The bidirectional parameters are anisotropic function, standard deviation of mean radiance, and shortwave-longwave radiance correlation coefficient. The directional parameters are mean albedo as a function of Sun zenith angle and mean albedo normalized to overhead Sun. Derivation of these models from the Nimbus 7 ERB (Earth Radiation Budget) and Geostationary Operational Environmental Satellite (GOES) data sets is described. Tabulated values and computer-generated plots are included for the bidirectional and directional modes.

  13. [Sensitive and selective HPLC methods with prechromatographic derivatization for the determination of cyclamate in foods].

    PubMed

    Rüter, J; Raczek, D I

    1992-06-01

    A sensitive and selective high pressure liquid chromatography (HPLC) procedure for the determination of sodium cyclamate in juices and preserves is presented. The method depends on the oxidation of cyclamate to cyclohexylamine, which then is converted prechromatographically into a fluorescent derivative. It is analyzed by HPLC on a C18:reversed-phase column and determined with fluorescence detection (excitation at 350 nm, emission at 440-650 nm). The detection limit of sodium cyclamate was 0.5-5 mg/kg, depending on the nature and dilution of the samples. The relative standard deviations thus obtained were +/- 1.0 to +/- 2.6%. The average recovery was 90%.

  14. Initial geomagnetic field model from MAGSAT

    NASA Technical Reports Server (NTRS)

    Langel, R. A.; Estes, R. H.; Mead, G. D.; Fabiano, E. B.; Lancaster, E. R.

    1980-01-01

    Magsat data from magnetically quiet days were used to derive a thirteenth degree and order spherical harmonic geomagnetic field model, MGST(3/80). The model utilized both scalar and vector data and fit that data with standard deviations of 8, 52, 55 and 97 nT for the scalar magnitude, B sub r, B sub theta and B sub phi respectively. When compared with earlier models, the Earth's dipole moment continues to decrease at a rate of about 26 nT/year. Evaluation of earlier models with Magsat data shows that the scalar field at the Magsat epoch is best predicted by the POGO(2/72) model but that the AWC/75 and IGS/75 are better for predicting vector fields.

  15. 2D massless Dirac Fermi gas model of superconductivity in the surface state of a topological insulator at high magnetic fields

    NASA Astrophysics Data System (ADS)

    Zhuravlev, Vladimir; Duan, Wenye; Maniv, Tsofar

    2017-10-01

    The Nambu-Gorkov Green's function approach is applied to strongly type-II superconductivity in a 2D spin-momentum-locked (Weyl) Fermi gas model at high perpendicular magnetic fields. The resulting phase diagram can be mapped onto that derived for the standard, parabolic band-structure model, having the same Fermi surface parameters, E F and v, but with cyclotron effective mass m\\ast=EF/2v2 . Significant deviations from the predicted mapping are found only for very small E F , when the Landau-Level filling factors are smaller than unity, and E F shrinks below the cutoff energy.

  16. Streamflow statistical summaries for Colorado streams through September 30, 1975; Volume 2, Colorado River basin

    USGS Publications Warehouse

    Petsch, Harold E.

    1979-01-01

    Statistical summaries of daily streamflow data for 189 stations west of the Continental Divide in Colorado are presented in this report. Duration tables, high-flow sequence tables, and low-flow sequence tables provide information about daily mean discharge. The mean, variance, standard deviation, skewness, and coefficient of variation are provided for monthly and annual flows. Percentages of average flow are provided for monthly flows and first-order serial-correlation coefficients are provided for annual flows. The text explain the nature and derivation of the data and illustrates applications of the tabulated information by examples. The data may be used by agencies and individuals engaged in water studies. (USGS)

  17. Evidence for the associated production of the Higgs boson and a top quark pair with the ATLAS detector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aaboud, M.; Aad, G.; Abbott, B.

    Here, a search for the associated production of the Higgs boson with a top quark pair (more » $$t\\bar{t}$$H) is reported. The search is performed in multilepton final states using a data set corresponding to an integrated luminosity of 36.1 fb -1 of proton-proton collision data recorded by the ATLAS experiment at a center-of-mass energy $$\\sqrt{s}$$ = 13 TeV at the Large Hadron Collider. Higgs boson decays to WW*, ττ, and ZZ* are targeted. Seven final states, categorized by the number and flavor of charged-lepton candidates, are examined for the presence of the Standard Model Higgs boson with a mass of 125 GeV and a pair of top quarks. An excess of events over the expected background from Standard Model processes is found with an observed significance of 4.1 standard deviations, compared to an expectation of 2.8 standard deviations. The best fit for the $$t\\bar{t}$$H production cross section is σ($$t\\bar{t}$$H) = $${790}_{-210}^{+230}$$ fb, in agreement with the Standard Model prediction of $${507}_{-50}^{+35}$$ fb. The combination of this result with other $$t\\bar{t}$$H searches from the ATLAS experiment using the Higgs boson decay modes to $$b\\bar{b}$$, γγ and ZZ* → 4ℓ, has an observed significance of 4.2 standard deviations, compared to an expectation of 3.8 standard deviations. This provides evidence for the $$t\\bar{t}$$H production mode.« less

  18. Evidence for the associated production of the Higgs boson and a top quark pair with the ATLAS detector

    DOE PAGES

    Aaboud, M.; Aad, G.; Abbott, B.; ...

    2018-04-09

    Here, a search for the associated production of the Higgs boson with a top quark pair (more » $$t\\bar{t}$$H) is reported. The search is performed in multilepton final states using a data set corresponding to an integrated luminosity of 36.1 fb -1 of proton-proton collision data recorded by the ATLAS experiment at a center-of-mass energy $$\\sqrt{s}$$ = 13 TeV at the Large Hadron Collider. Higgs boson decays to WW*, ττ, and ZZ* are targeted. Seven final states, categorized by the number and flavor of charged-lepton candidates, are examined for the presence of the Standard Model Higgs boson with a mass of 125 GeV and a pair of top quarks. An excess of events over the expected background from Standard Model processes is found with an observed significance of 4.1 standard deviations, compared to an expectation of 2.8 standard deviations. The best fit for the $$t\\bar{t}$$H production cross section is σ($$t\\bar{t}$$H) = $${790}_{-210}^{+230}$$ fb, in agreement with the Standard Model prediction of $${507}_{-50}^{+35}$$ fb. The combination of this result with other $$t\\bar{t}$$H searches from the ATLAS experiment using the Higgs boson decay modes to $$b\\bar{b}$$, γγ and ZZ* → 4ℓ, has an observed significance of 4.2 standard deviations, compared to an expectation of 3.8 standard deviations. This provides evidence for the $$t\\bar{t}$$H production mode.« less

  19. Evidence for the associated production of the Higgs boson and a top quark pair with the ATLAS detector

    NASA Astrophysics Data System (ADS)

    Aaboud, M.; Aad, G.; Abbott, B.; Abdinov, O.; Abeloos, B.; Abidi, S. H.; Abouzeid, O. S.; Abraham, N. L.; Abramowicz, H.; Abreu, H.; Abulaiti, Y.; Acharya, B. S.; Adachi, S.; Adamczyk, L.; Adelman, J.; Adersberger, M.; Adye, T.; Affolder, A. A.; Afik, Y.; Agheorghiesei, C.; Aguilar-Saavedra, J. A.; Ahlen, S. P.; Ahmadov, F.; Aielli, G.; Akatsuka, S.; Åkesson, T. P. A.; Akilli, E.; Akimov, A. V.; Alberghi, G. L.; Albert, J.; Albicocco, P.; Alconada Verzini, M. J.; Alderweireldt, S. C.; Aleksa, M.; Aleksandrov, I. N.; Alexa, C.; Alexander, G.; Alexopoulos, T.; Alhroob, M.; Ali, B.; Aliev, M.; Alimonti, G.; Alison, J.; Alkire, S. P.; Allaire, C.; Allbrooke, B. M. M.; Allen, B. W.; Allport, P. P.; Aloisio, A.; Alonso, A.; Alonso, F.; Alpigiani, C.; Alshehri, A. A.; Alstaty, M. I.; Alvarez Gonzalez, B.; Álvarez Piqueras, D.; Alviggi, M. G.; Amadio, B. T.; Amaral Coutinho, Y.; Ambroz, L.; Amelung, C.; Amidei, D.; Amor Dos Santos, S. P.; Amoroso, S.; Anastopoulos, C.; Ancu, L. S.; Andari, N.; Andeen, T.; Anders, C. F.; Anders, J. K.; Anderson, K. J.; Andreazza, A.; Andrei, V.; Angelidakis, S.; Angelozzi, I.; Angerami, A.; Anisenkov, A. V.; Annovi, A.; Antel, C.; Antonelli, M.; Antonov, A.; Antrim, D. J.; Anulli, F.; Aoki, M.; Aperio Bella, L.; Arabidze, G.; Arai, Y.; Araque, J. P.; Araujo Ferraz, V.; Arce, A. T. H.; Ardell, R. E.; Arduh, F. A.; Arguin, J.-F.; Argyropoulos, S.; Armbruster, A. J.; Armitage, L. J.; Arnaez, O.; Arnold, H.; Arratia, M.; Arslan, O.; Artamonov, A.; Artoni, G.; Artz, S.; Asai, S.; Asbah, N.; Ashkenazi, A.; Asquith, L.; Assamagan, K.; Astalos, R.; Atkin, R. J.; Atkinson, M.; Atlay, N. B.; Augsten, K.; Avolio, G.; Avramidou, R.; Axen, B.; Ayoub, M. K.; Azuelos, G.; Baas, A. E.; Baca, M. J.; Bachacou, H.; Bachas, K.; Backes, M.; Bagnaia, P.; Bahmani, M.; Bahrasemani, H.; Baines, J. T.; Bajic, M.; Baker, O. K.; Bakker, P. J.; Bakshi Gupta, D.; Baldin, E. M.; Balek, P.; Balli, F.; Balunas, W. K.; Banas, E.; Bandyopadhyay, A.; Banerjee, Sw.; Bannoura, A. A. E.; Barak, L.; Barberio, E. L.; Barberis, D.; Barbero, M.; Barillari, T.; Barisits, M.-S.; Barkeloo, J. T.; Barklow, T.; Barlow, N.; Barnea, R.; Barnes, S. L.; Barnett, B. M.; Barnett, R. M.; Barnovska-Blenessy, Z.; Baroncelli, A.; Barone, G.; Barr, A. J.; Barranco Navarro, L.; Barreiro, F.; Barreiro Guimarães da Costa, J.; Bartoldus, R.; Barton, A. E.; Bartos, P.; Basalaev, A.; Bassalat, A.; Bates, R. L.; Batista, S. J.; Batley, J. R.; Battaglia, M.; Bauce, M.; Bauer, F.; Bauer, K. T.; Bawa, H. S.; Beacham, J. B.; Beattie, M. D.; Beau, T.; Beauchemin, P. H.; Bechtle, P.; Beck, H. P.; Beck, H. C.; Becker, K.; Becker, M.; Becot, C.; Beddall, A. J.; Beddall, A.; Bednyakov, V. A.; Bedognetti, M.; Bee, C. P.; Beermann, T. A.; Begalli, M.; Begel, M.; Behera, A.; Behr, J. K.; Bell, A. S.; Bella, G.; Bellagamba, L.; Bellerive, A.; Bellomo, M.; Belotskiy, K.; Belyaev, N. L.; Benary, O.; Benchekroun, D.; Bender, M.; Benekos, N.; Benhammou, Y.; Benhar Noccioli, E.; Benitez, J.; Benjamin, D. P.; Benoit, M.; Bensinger, J. R.; Bentvelsen, S.; Beresford, L.; Beretta, M.; Berge, D.; Bergeaas Kuutmann, E.; Berger, N.; Bergsten, L. J.; Beringer, J.; Berlendis, S.; Bernard, N. R.; Bernardi, G.; Bernius, C.; Bernlochner, F. U.; Berry, T.; Berta, P.; Bertella, C.; Bertoli, G.; Bertram, I. A.; Bertsche, C.; Besjes, G. J.; Bessidskaia Bylund, O.; Bessner, M.; Besson, N.; Bethani, A.; Bethke, S.; Betti, A.; Bevan, A. J.; Beyer, J.; Bianchi, R. M.; Biebel, O.; Biedermann, D.; Bielski, R.; Bierwagen, K.; Biesuz, N. V.; Biglietti, M.; Billoud, T. R. V.; Bindi, M.; Bingul, A.; Bini, C.; Biondi, S.; Bisanz, T.; Bittrich, C.; Bjergaard, D. M.; Black, J. E.; Black, K. M.; Blair, R. E.; Blazek, T.; Bloch, I.; Blocker, C.; Blue, A.; Blumenschein, U.; Blunier, Dr.; Bobbink, G. J.; Bobrovnikov, V. S.; Bocchetta, S. S.; Bocci, A.; Bock, C.; Boerner, D.; Bogavac, D.; Bogdanchikov, A. G.; Bohm, C.; Boisvert, V.; Bokan, P.; Bold, T.; Boldyrev, A. S.; Bolz, A. E.; Bomben, M.; Bona, M.; Bonilla, J. S.; Boonekamp, M.; Borisov, A.; Borissov, G.; Bortfeldt, J.; Bortoletto, D.; Bortolotto, V.; Boscherini, D.; Bosman, M.; Bossio Sola, J. D.; Boudreau, J.; Bouhova-Thacker, E. V.; Boumediene, D.; Bourdarios, C.; Boutle, S. K.; Boveia, A.; Boyd, J.; Boyko, I. R.; Bozson, A. J.; Bracinik, J.; Brandt, A.; Brandt, G.; Brandt, O.; Braren, F.; Bratzler, U.; Brau, B.; Brau, J. E.; Breaden Madden, W. D.; Brendlinger, K.; Brennan, A. J.; Brenner, L.; Brenner, R.; Bressler, S.; Briglin, D. L.; Bristow, T. M.; Britton, D.; Britzger, D.; Brock, I.; Brock, R.; Brooijmans, G.; Brooks, T.; Brooks, W. K.; Brost, E.; Broughton, J. H.; Bruckman de Renstrom, P. A.; Bruncko, D.; Bruni, A.; Bruni, G.; Bruni, L. S.; Bruno, S.; Brunt, Bh; Bruschi, M.; Bruscino, N.; Bryant, P.; Bryngemark, L.; Buanes, T.; Buat, Q.; Buchholz, P.; Buckley, A. G.; Budagov, I. A.; Buehrer, F.; Bugge, M. K.; Bulekov, O.; Bullock, D.; Burch, T. J.; Burdin, S.; Burgard, C. D.; Burger, A. M.; Burghgrave, B.; Burka, K.; Burke, S.; Burmeister, I.; Burr, J. T. P.; Büscher, D.; Büscher, V.; Buschmann, E.; Bussey, P.; Butler, J. M.; Buttar, C. M.; Butterworth, J. M.; Butti, P.; Buttinger, W.; Buzatu, A.; Buzykaev, A. R.; Cabras, G.; Cabrera Urbán, S.; Caforio, D.; Cai, H.; Cairo, V. M. M.; Cakir, O.; Calace, N.; Calafiura, P.; Calandri, A.; Calderini, G.; Calfayan, P.; Callea, G.; Caloba, L. P.; Calvente Lopez, S.; Calvet, D.; Calvet, S.; Calvet, T. P.; Camacho Toro, R.; Camarda, S.; Camarri, P.; Cameron, D.; Caminal Armadans, R.; Camincher, C.; Campana, S.; Campanelli, M.; Camplani, A.; Campoverde, A.; Canale, V.; Cano Bret, M.; Cantero, J.; Cao, T.; Capeans Garrido, M. D. M.; Caprini, I.; Caprini, M.; Capua, M.; Carbone, R. M.; Cardarelli, R.; Cardillo, F.; Carli, I.; Carli, T.; Carlino, G.; Carlson, B. T.; Carminati, L.; Carney, R. M. D.; Caron, S.; Carquin, E.; Carrá, S.; Carrillo-Montoya, G. D.; Casadei, D.; Casado, M. P.; Casha, A. F.; Casolino, M.; Casper, D. W.; Castelijn, R.; Castillo Gimenez, V.; Castro, N. F.; Catinaccio, A.; Catmore, J. R.; Cattai, A.; Caudron, J.; Cavaliere, V.; Cavallaro, E.; Cavalli, D.; Cavalli-Sforza, M.; Cavasinni, V.; Celebi, E.; Ceradini, F.; Cerda Alberich, L.; Cerqueira, A. S.; Cerri, A.; Cerrito, L.; Cerutti, F.; Cervelli, A.; Cetin, S. A.; Chafaq, A.; Chakraborty, D.; Chan, S. K.; Chan, W. S.; Chan, Y. L.; Chang, P.; Chapman, J. D.; Charlton, D. G.; Chau, C. C.; Chavez Barajas, C. A.; Che, S.; Chegwidden, A.; Chekanov, S.; Chekulaev, S. V.; Chelkov, G. A.; Chelstowska, M. A.; Chen, C.; Chen, C.; Chen, H.; Chen, J.; Chen, J.; Chen, S.; Chen, S.; Chen, X.; Chen, Y.; Cheng, H. C.; Cheng, H. J.; Cheplakov, A.; Cheremushkina, E.; Cherkaoui El Moursli, R.; Cheu, E.; Cheung, K.; Chevalier, L.; Chiarella, V.; Chiarelli, G.; Chiodini, G.; Chisholm, A. S.; Chitan, A.; Chiu, Y. H.; Chizhov, M. V.; Choi, K.; Chomont, A. R.; Chouridou, S.; Chow, Y. S.; Christodoulou, V.; Chu, M. C.; Chudoba, J.; Chuinard, A. J.; Chwastowski, J. J.; Chytka, L.; Cinca, D.; Cindro, V.; Cioarǎ, I. A.; Ciocio, A.; Cirotto, F.; Citron, Z. H.; Citterio, M.; Clark, A.; Clark, M. R.; Clark, P. J.; Clarke, R. N.; Clement, C.; Coadou, Y.; Cobal, M.; Coccaro, A.; Cochran, J.; Colasurdo, L.; Cole, B.; Colijn, A. P.; Collot, J.; Conde Muiño, P.; Coniavitis, E.; Connell, S. H.; Connelly, I. A.; Constantinescu, S.; Conti, G.; Conventi, F.; Cooper-Sarkar, A. M.; Cormier, F.; Cormier, K. J. R.; Corradi, M.; Corrigan, E. E.; Corriveau, F.; Cortes-Gonzalez, A.; Costa, M. J.; Costanzo, D.; Cottin, G.; Cowan, G.; Cox, B. E.; Cranmer, K.; Crawley, S. J.; Creager, R. A.; Cree, G.; Crépé-Renaudin, S.; Crescioli, F.; Cristinziani, M.; Croft, V.; Crosetti, G.; Cueto, A.; Cuhadar Donszelmann, T.; Cukierman, A. R.; Cummings, J.; Curatolo, M.; Cúth, J.; Czekierda, S.; Czodrowski, P.; D'Amen, G.; D'Auria, S.; D'Eramo, L.; D'Onofrio, M.; da Cunha Sargedas de Sousa, M. J.; da Via, C.; Dabrowski, W.; Dado, T.; Dahbi, S.; Dai, T.; Dale, O.; Dallaire, F.; Dallapiccola, C.; Dam, M.; Dandoy, J. R.; Daneri, M. F.; Dang, N. P.; Dann, N. S.; Danninger, M.; Dano Hoffmann, M.; Dao, V.; Darbo, G.; Darmora, S.; Dattagupta, A.; Daubney, T.; Davey, W.; David, C.; Davidek, T.; Davis, D. R.; Davison, P.; Dawe, E.; Dawson, I.; de, K.; de Asmundis, R.; de Benedetti, A.; de Castro, S.; de Cecco, S.; de Groot, N.; de Jong, P.; de la Torre, H.; de Lorenzi, F.; de Maria, A.; de Pedis, D.; de Salvo, A.; de Sanctis, U.; de Santo, A.; de Vasconcelos Corga, K.; de Vivie de Regie, J. B.; Debenedetti, C.; Dedovich, D. V.; Dehghanian, N.; Deigaard, I.; Del Gaudio, M.; Del Peso, J.; Delgove, D.; Deliot, F.; Delitzsch, C. M.; Dell'Acqua, A.; Dell'Asta, L.; Della Pietra, M.; Della Volpe, D.; Delmastro, M.; Delporte, C.; Delsart, P. A.; Demarco, D. A.; Demers, S.; Demichev, M.; Denisov, S. P.; Denysiuk, D.; Derendarz, D.; Derkaoui, J. E.; Derue, F.; Dervan, P.; Desch, K.; Deterre, C.; Dette, K.; Devesa, M. R.; Deviveiros, P. O.; Dewhurst, A.; Dhaliwal, S.; di Bello, F. A.; di Ciaccio, A.; di Ciaccio, L.; di Clemente, W. K.; di Donato, C.; di Girolamo, A.; di Micco, B.; di Nardo, R.; di Petrillo, K. F.; di Simone, A.; di Sipio, R.; di Valentino, D.; Diaconu, C.; Diamond, M.; Dias, F. A.; Diaz, M. A.; Dickinson, J.; Diehl, E. B.; Dietrich, J.; Díez Cornell, S.; Dimitrievska, A.; Dingfelder, J.; Dita, P.; Dita, S.; Dittus, F.; Djama, F.; Djobava, T.; Djuvsland, J. I.; Do Vale, M. A. B.; Dobre, M.; Dodsworth, D.; Doglioni, C.; Dolejsi, J.; Dolezal, Z.; Donadelli, M.; Donati, S.; Donini, J.; Dopke, J.; Doria, A.; Dova, M. T.; Doyle, A. T.; Drechsler, E.; Dreyer, E.; Dris, M.; Du, Y.; Duarte-Campderros, J.; Dubinin, F.; Dubreuil, A.; Duchovni, E.; Duckeck, G.; Ducourthial, A.; Ducu, O. A.; Duda, D.; Dudarev, A.; Dudder, A. Chr.; Duffield, E. M.; Duflot, L.; Dührssen, M.; Dulsen, C.; Dumancic, M.; Dumitriu, A. E.; Duncan, A. K.; Dunford, M.; Duperrin, A.; Duran Yildiz, H.; Düren, M.; Durglishvili, A.; Duschinger, D.; Dutta, B.; Duvnjak, D.; Dyndal, M.; Dziedzic, B. S.; Eckardt, C.; Ecker, K. M.; Edgar, R. C.; Eifert, T.; Eigen, G.; Einsweiler, K.; Ekelof, T.; El Kacimi, M.; El Kosseifi, R.; Ellajosyula, V.; Ellert, M.; Ellinghaus, F.; Elliot, A. A.; Ellis, N.; Elmsheuser, J.; Elsing, M.; Emeliyanov, D.; Enari, Y.; Ennis, J. S.; Epland, M. B.; Erdmann, J.; Ereditato, A.; Errede, S.; Escalier, M.; Escobar, C.; Esposito, B.; Estrada Pastor, O.; Etienvre, A. I.; Etzion, E.; Evans, H.; Ezhilov, A.; Ezzi, M.; Fabbri, F.; Fabbri, L.; Fabiani, V.; Facini, G.; Fakhrutdinov, R. M.; Falciano, S.; Faltova, J.; Fang, Y.; Fanti, M.; Farbin, A.; Farilla, A.; Farina, E. M.; Farooque, T.; Farrell, S.; Farrington, S. M.; Farthouat, P.; Fassi, F.; Fassnacht, P.; Fassouliotis, D.; Faucci Giannelli, M.; Favareto, A.; Fawcett, W. J.; Fayard, L.; Fedin, O. L.; Fedorko, W.; Feickert, M.; Feigl, S.; Feligioni, L.; Feng, C.; Feng, E. J.; Feng, M.; Fenton, M. J.; Fenyuk, A. B.; Feremenga, L.; Fernandez Martinez, P.; Ferrando, J.; Ferrari, A.; Ferrari, P.; Ferrari, R.; Ferreira de Lima, D. E.; Ferrer, A.; Ferrere, D.; Ferretti, C.; Fiedler, F.; Filipčič, A.; Filthaut, F.; Fincke-Keeler, M.; Finelli, K. D.; Fiolhais, M. C. N.; Fiorini, L.; Fischer, C.; Fischer, J.; Fisher, W. C.; Flaschel, N.; Fleck, I.; Fleischmann, P.; Fletcher, R. R. M.; Flick, T.; Flierl, B. M.; Flores, L. M.; Flores Castillo, L. R.; Fomin, N.; Forcolin, G. T.; Formica, A.; Förster, F. A.; Forti, A.; Foster, A. G.; Fournier, D.; Fox, H.; Fracchia, S.; Francavilla, P.; Franchini, M.; Franchino, S.; Francis, D.; Franconi, L.; Franklin, M.; Frate, M.; Fraternali, M.; Freeborn, D.; Fressard-Batraneanu, S. M.; Freund, B.; Freund, W. S.; Froidevaux, D.; Frost, J. A.; Fukunaga, C.; Fusayasu, T.; Fuster, J.; Gabizon, O.; Gabrielli, A.; Gabrielli, A.; Gach, G. P.; Gadatsch, S.; Gadomski, S.; Gagliardi, G.; Gagnon, L. G.; Galea, C.; Galhardo, B.; Gallas, E. J.; Gallop, B. J.; Gallus, P.; Galster, G.; Gan, K. K.; Ganguly, S.; Gao, Y.; Gao, Y. S.; Garay Walls, F. M.; García, C.; García Navarro, J. E.; García Pascual, J. A.; Garcia-Sciveres, M.; Gardner, R. W.; Garelli, N.; Garonne, V.; Gasnikova, K.; Gaudiello, A.; Gaudio, G.; Gavrilenko, I. L.; Gay, C.; Gaycken, G.; Gazis, E. N.; Gee, C. N. P.; Geisen, J.; Geisen, M.; Geisler, M. P.; Gellerstedt, K.; Gemme, C.; Genest, M. H.; Geng, C.; Gentile, S.; Gentsos, C.; George, S.; Gerbaudo, D.; Geßner, G.; Ghasemi, S.; Ghneimat, M.; Giacobbe, B.; Giagu, S.; Giangiacomi, N.; Giannetti, P.; Gibson, S. M.; Gignac, M.; Gilchriese, M.; Gillberg, D.; Gilles, G.; Gingrich, D. M.; Giordani, M. P.; Giorgi, F. M.; Giraud, P. F.; Giromini, P.; Giugliarelli, G.; Giugni, D.; Giuli, F.; Giulini, M.; Gkaitatzis, S.; Gkialas, I.; Gkougkousis, E. L.; Gkountoumis, P.; Gladilin, L. K.; Glasman, C.; Glatzer, J.; Glaysher, P. C. F.; Glazov, A.; Goblirsch-Kolb, M.; Godlewski, J.; Goldfarb, S.; Golling, T.; Golubkov, D.; Gomes, A.; Gonçalo, R.; Goncalves Gama, R.; Gonella, G.; Gonella, L.; Gongadze, A.; Gonnella, F.; Gonski, J. L.; González de La Hoz, S.; Gonzalez-Sevilla, S.; Goossens, L.; Gorbounov, P. A.; Gordon, H. A.; Gorini, B.; Gorini, E.; Gorišek, A.; Goshaw, A. T.; Gössling, C.; Gostkin, M. I.; Gottardo, C. A.; Goudet, C. R.; Goujdami, D.; Goussiou, A. G.; Govender, N.; Goy, C.; Gozani, E.; Grabowska-Bold, I.; Gradin, P. O. J.; Graham, E. C.; Gramling, J.; Gramstad, E.; Grancagnolo, S.; Gratchev, V.; Gravila, P. M.; Gray, C.; Gray, H. M.; Greenwood, Z. D.; Grefe, C.; Gregersen, K.; Gregor, I. M.; Grenier, P.; Grevtsov, K.; Griffiths, J.; Grillo, A. A.; Grimm, K.; Grinstein, S.; Gris, Ph.; Grivaz, J.-F.; Groh, S.; Gross, E.; Grosse-Knetter, J.; Grossi, G. C.; Grout, Z. J.; Grummer, A.; Guan, L.; Guan, W.; Guenther, J.; Guerguichon, A.; Guescini, F.; Guest, D.; Gueta, O.; Gugel, R.; Gui, B.; Guillemin, T.; Guindon, S.; Gul, U.; Gumpert, C.; Guo, J.; Guo, W.; Guo, Y.; Gupta, R.; Gurbuz, S.; Gustavino, G.; Gutelman, B. J.; Gutierrez, P.; Gutierrez Ortiz, N. G.; Gutschow, C.; Guyot, C.; Guzik, M. P.; Gwenlan, C.; Gwilliam, C. B.; Haas, A.; Haber, C.; Hadavand, H. K.; Haddad, N.; Hadef, A.; Hageböck, S.; Hagihara, M.; Hakobyan, H.; Haleem, M.; Haley, J.; Halladjian, G.; Hallewell, G. D.; Hamacher, K.; Hamal, P.; Hamano, K.; Hamilton, A.; Hamity, G. N.; Han, K.; Han, L.; Han, S.; Hanagaki, K.; Hance, M.; Handl, D. M.; Haney, B.; Hankache, R.; Hanke, P.; Hansen, E.; Hansen, J. B.; Hansen, J. D.; Hansen, M. C.; Hansen, P. H.; Hara, K.; Hard, A. S.; Harenberg, T.; Harkusha, S.; Harrison, P. F.; Hartmann, N. M.; Hasegawa, Y.; Hasib, A.; Hassani, S.; Haug, S.; Hauser, R.; Hauswald, L.; Havener, L. B.; Havranek, M.; Hawkes, C. M.; Hawkings, R. J.; Hayden, D.; Hays, C. P.; Hays, J. M.; Hayward, H. S.; Haywood, S. J.; Heck, T.; Hedberg, V.; Heelan, L.; Heer, S.; Heidegger, K. K.; Heim, S.; Heim, T.; Heinemann, B.; Heinrich, J. J.; Heinrich, L.; Heinz, C.; Hejbal, J.; Helary, L.; Held, A.; Hellman, S.; Helsens, C.; Henderson, R. C. W.; Heng, Y.; Henkelmann, S.; Henriques Correia, A. M.; Herbert, G. H.; Herde, H.; Herget, V.; Hernández Jiménez, Y.; Herr, H.; Herten, G.; Hertenberger, R.; Hervas, L.; Herwig, T. C.; Hesketh, G. G.; Hessey, N. P.; Hetherly, J. W.; Higashino, S.; Higón-Rodriguez, E.; Hildebrand, K.; Hill, E.; Hill, J. C.; Hiller, K. H.; Hillier, S. J.; Hils, M.; Hinchliffe, I.; Hirose, M.; Hirschbuehl, D.; Hiti, B.; Hladik, O.; Hlaluku, D. R.; Hoad, X.; Hobbs, J.; Hod, N.; Hodgkinson, M. C.; Hoecker, A.; Hoeferkamp, M. R.; Hoenig, F.; Hohn, D.; Hohov, D.; Holmes, T. R.; Holzbock, M.; Homann, M.; Honda, S.; Honda, T.; Hong, T. M.; Hooberman, B. H.; Hopkins, W. H.; Horii, Y.; Horton, A. J.; Horyn, L. A.; Hostachy, J.-Y.; Hostiuc, A.; Hou, S.; Hoummada, A.; Howarth, J.; Hoya, J.; Hrabovsky, M.; Hrdinka, J.; Hristova, I.; Hrivnac, J.; Hryn'ova, T.; Hrynevich, A.; Hsu, P. J.; Hsu, S.-C.; Hu, Q.; Hu, S.; Huang, Y.; Hubacek, Z.; Hubaut, F.; Huegging, F.; Huffman, T. B.; Hughes, E. W.; Huhtinen, M.; Hunter, R. F. H.; Huo, P.; Hupe, A. M.; Huseynov, N.; Huston, J.; Huth, J.; Hyneman, R.; Iacobucci, G.; Iakovidis, G.; Ibragimov, I.; Iconomidou-Fayard, L.; Idrissi, Z.; Iengo, P.; Igonkina, O.; Iguchi, R.; Iizawa, T.; Ikegami, Y.; Ikeno, M.; Iliadis, D.; Ilic, N.; Iltzsche, F.; Introzzi, G.; Iodice, M.; Iordanidou, K.; Ippolito, V.; Isacson, M. F.; Ishijima, N.; Ishino, M.; Ishitsuka, M.; Issever, C.; Istin, S.; Ito, F.; Iturbe Ponce, J. M.; Iuppa, R.; Iwasaki, H.; Izen, J. M.; Izzo, V.; Jabbar, S.; Jackson, P.; Jacobs, R. M.; Jain, V.; Jakel, G.; Jakobi, K. B.; Jakobs, K.; Jakobsen, S.; Jakoubek, T.; Jamin, D. O.; Jana, D. K.; Jansky, R.; Janssen, J.; Janus, M.; Janus, P. A.; Jarlskog, G.; Javadov, N.; Javå¯Rek, T.; Javurkova, M.; Jeanneau, F.; Jeanty, L.; Jejelava, J.; Jelinskas, A.; Jenni, P.; Jeske, C.; Jézéquel, S.; Ji, H.; Jia, J.; Jiang, H.; Jiang, Y.; Jiang, Z.; Jiggins, S.; Jimenez Pena, J.; Jin, S.; Jinaru, A.; Jinnouchi, O.; Jivan, H.; Johansson, P.; Johns, K. A.; Johnson, C. A.; Johnson, W. J.; Jon-And, K.; Jones, R. W. L.; Jones, S. D.; Jones, S.; Jones, T. J.; Jongmanns, J.; Jorge, P. M.; Jovicevic, J.; Ju, X.; Junggeburth, J. J.; Juste Rozas, A.; Kaczmarska, A.; Kado, M.; Kagan, H.; Kagan, M.; Kahn, S. J.; Kaji, T.; Kajomovitz, E.; Kalderon, C. W.; Kaluza, A.; Kama, S.; Kamenshchikov, A.; Kanjir, L.; Kano, Y.; Kantserov, V. A.; Kanzaki, J.; Kaplan, B.; Kaplan, L. S.; Kar, D.; Karakostas, K.; Karastathis, N.; Kareem, M. J.; Karentzos, E.; Karpov, S. N.; Karpova, Z. M.; Kartvelishvili, V.; Karyukhin, A. N.; Kasahara, K.; Kashif, L.; Kass, R. D.; Kastanas, A.; Kataoka, Y.; Kato, C.; Katre, A.; Katzy, J.; Kawade, K.; Kawagoe, K.; Kawamoto, T.; Kawamura, G.; Kay, E. F.; Kazanin, V. F.; Keeler, R.; Kehoe, R.; Keller, J. S.; Kellermann, E.; Kempster, J. J.; Kendrick, J.; Keoshkerian, H.; Kepka, O.; Kerševan, B. P.; Kersten, S.; Keyes, R. A.; Khader, M.; Khalil-Zada, F.; Khanov, A.; Kharlamov, A. G.; Kharlamova, T.; Khodinov, A.; Khoo, T. J.; Khovanskiy, V.; Khramov, E.; Khubua, J.; Kido, S.; Kiehn, M.; Kilby, C. R.; Kim, H. Y.; Kim, S. H.; Kim, Y. K.; Kimura, N.; Kind, O. M.; King, B. T.; Kirchmeier, D.; Kirk, J.; Kiryunin, A. E.; Kishimoto, T.; Kisielewska, D.; Kitali, V.; Kivernyk, O.; Kladiva, E.; Klapdor-Kleingrothaus, T.; Klein, M. H.; Klein, M.; Klein, U.; Kleinknecht, K.; Klimek, P.; Klimentov, A.; Klingenberg, R.; Klingl, T.; Klioutchnikova, T.; Klitzner, F. F.; Kluge, E.-E.; Kluit, P.; Kluth, S.; Kneringer, E.; Knoops, E. B. F. G.; Knue, A.; Kobayashi, A.; Kobayashi, D.; Kobayashi, T.; Kobel, M.; Kocian, M.; Kodys, P.; Koffas, T.; Koffeman, E.; Köhler, N. M.; Koi, T.; Kolb, M.; Koletsou, I.; Kondo, T.; Kondrashova, N.; Köneke, K.; König, A. C.; Kono, T.; Konoplich, R.; Konstantinidis, N.; Konya, B.; Kopeliansky, R.; Koperny, S.; Korcyl, K.; Kordas, K.; Korn, A.; Korolkov, I.; Korolkova, E. V.; Kortner, O.; Kortner, S.; Kosek, T.; Kostyukhin, V. V.; Kotwal, A.; Koulouris, A.; Kourkoumeli-Charalampidi, A.; Kourkoumelis, C.; Kourlitis, E.; Kouskoura, V.; Kowalewska, A. B.; Kowalewski, R.; Kowalski, T. Z.; Kozakai, C.; Kozanecki, W.; Kozhin, A. S.; Kramarenko, V. A.; Kramberger, G.; Krasnopevtsev, D.; Krasny, M. W.; Krasznahorkay, A.; Krauss, D.; Kremer, J. A.; Kretzschmar, J.; Kreutzfeldt, K.; Krieger, P.; Krizka, K.; Kroeninger, K.; Kroha, H.; Kroll, J.; Kroll, J.; Kroseberg, J.; Krstic, J.; Kruchonak, U.; Krüger, H.; Krumnack, N.; Kruse, M. C.; Kubota, T.; Kuday, S.; Kuechler, J. T.; Kuehn, S.; Kugel, A.; Kuger, F.; Kuhl, T.; Kukhtin, V.; Kukla, R.; Kulchitsky, Y.; Kuleshov, S.; Kulinich, Y. P.; Kuna, M.; Kunigo, T.; Kupco, A.; Kupfer, T.; Kuprash, O.; Kurashige, H.; Kurchaninov, L. L.; Kurochkin, Y. A.; Kurth, M. G.; Kuwertz, E. S.; Kuze, M.; Kvita, J.; Kwan, T.; La Rosa, A.; La Rosa Navarro, J. L.; La Rotonda, L.; La Ruffa, F.; Lacasta, C.; Lacava, F.; Lacey, J.; Lack, D. P. J.; Lacker, H.; Lacour, D.; Ladygin, E.; Lafaye, R.; Laforge, B.; Lai, S.; Lammers, S.; Lampl, W.; Lançon, E.; Landgraf, U.; Landon, M. P. J.; Lanfermann, M. C.; Lang, V. S.; Lange, J. C.; Langenberg, R. J.; Lankford, A. J.; Lanni, F.; Lantzsch, K.; Lanza, A.; Lapertosa, A.; Laplace, S.; Laporte, J. F.; Lari, T.; Lasagni Manghi, F.; Lassnig, M.; Lau, T. S.; Laudrain, A.; Law, A. T.; Laycock, P.; Lazzaroni, M.; Le, B.; Le Dortz, O.; Le Guirriec, E.; Le Quilleuc, E. P.; Leblanc, M.; Lecompte, T.; Ledroit-Guillon, F.; Lee, C. A.; Lee, G. R.; Lee, S. C.; Lee, L.; Lefebvre, B.; Lefebvre, M.; Legger, F.; Leggett, C.; Lehmann Miotto, G.; Leight, W. A.; Leisos, A.; Leite, M. A. L.; Leitner, R.; Lellouch, D.; Lemmer, B.; Leney, K. J. C.; Lenz, T.; Lenzi, B.; Leone, R.; Leone, S.; Leonidopoulos, C.; Lerner, G.; Leroy, C.; Les, R.; Lesage, A. A. J.; Lester, C. G.; Levchenko, M.; Levêque, J.; Levin, D.; Levinson, L. J.; Levy, M.; Lewis, D.; Li, B.; Li, C.-Q.; Li, H.; Li, L.; Li, Q.; Li, Q.; Li, S.; Li, X.; Li, Y.; Liang, Z.; Liberti, B.; Liblong, A.; Lie, K.; Limosani, A.; Lin, C. Y.; Lin, K.; Lin, S. C.; Lin, T. H.; Linck, R. A.; Lindquist, B. E.; Lionti, A. E.; Lipeles, E.; Lipniacka, A.; Lisovyi, M.; Liss, T. M.; Lister, A.; Litke, A. M.; Liu, B.; Liu, H.; Liu, H.; Liu, J. K. K.; Liu, J. B.; Liu, K.; Liu, M.; Liu, P.; Liu, Y. L.; Liu, Y.; Livan, M.; Lleres, A.; Llorente Merino, J.; Lloyd, S. L.; Lo, C. Y.; Lo Sterzo, F.; Lobodzinska, E. M.; Loch, P.; Loebinger, F. K.; Loesle, A.; Loew, K. M.; Lohse, T.; Lohwasser, K.; Lokajicek, M.; Long, B. A.; Long, J. D.; Long, R. E.; Longo, L.; Looper, K. A.; Lopez, J. A.; Lopez Paz, I.; Lopez Solis, A.; Lorenz, J.; Lorenzo Martinez, N.; Losada, M.; Lösel, P. J.; Lou, X.; Lounis, A.; Love, J.; Love, P. A.; Lu, H.; Lu, N.; Lu, Y. J.; Lubatti, H. J.; Luci, C.; Lucotte, A.; Luedtke, C.; Luehring, F.; Lukas, W.; Luminari, L.; Lund-Jensen, B.; Lutz, M. S.; Luzi, P. M.; Lynn, D.; Lysak, R.; Lytken, E.; Lyu, F.; Lyubushkin, V.; Ma, H.; Ma, L. L.; Ma, Y.; Maccarrone, G.; Macchiolo, A.; MacDonald, C. M.; Maček, B.; Machado Miguens, J.; Madaffari, D.; Madar, R.; Mader, W. F.; Madsen, A.; Madysa, N.; Maeda, J.; Maeland, S.; Maeno, T.; Maevskiy, A. S.; Magerl, V.; Maidantchik, C.; Maier, T.; Maio, A.; Majersky, O.; Majewski, S.; Makida, Y.; Makovec, N.; Malaescu, B.; Malecki, Pa.; Maleev, V. P.; Malek, F.; Mallik, U.; Malon, D.; Malone, C.; Maltezos, S.; Malyukov, S.; Mamuzic, J.; Mancini, G.; Mandić, I.; Maneira, J.; Manhaes de Andrade Filho, L.; Manjarres Ramos, J.; Mankinen, K. H.; Mann, A.; Manousos, A.; Mansoulie, B.; Mansour, J. D.; Mantifel, R.; Mantoani, M.; Manzoni, S.; Marceca, G.; March, L.; Marchese, L.; Marchiori, G.; Marcisovsky, M.; Marin Tobon, C. A.; Marjanovic, M.; Marley, D. E.; Marroquim, F.; Marshall, Z.; Martensson, M. U. F.; Marti-Garcia, S.; Martin, C. B.; Martin, T. A.; Martin, V. J.; Martin Dit Latour, B.; Martinez, M.; Martinez Outschoorn, V. I.; Martin-Haugh, S.; Martoiu, V. S.; Martyniuk, A. C.; Marzin, A.; Masetti, L.; Mashimo, T.; Mashinistov, R.; Masik, J.; Maslennikov, A. L.; Mason, L. H.; Massa, L.; Mastrandrea, P.; Mastroberardino, A.; Masubuchi, T.; Mättig, P.; Maurer, J.; Maxfield, S. J.; Maximov, D. A.; Mazini, R.; Maznas, I.; Mazza, S. M.; Mc Fadden, N. C.; Mc Goldrick, G.; Mc Kee, S. P.; McCarn, A.; McCarthy, T. G.; McClymont, L. I.; McDonald, E. F.; McFayden, J. A.; McHedlidze, G.; McKay, M. A.; McMahon, S. J.; McNamara, P. C.; McNicol, C. J.; McPherson, R. A.; Meadows, Z. A.; Meehan, S.; Megy, T. J.; Mehlhase, S.; Mehta, A.; Meideck, T.; Meier, K.; Meirose, B.; Melini, D.; Mellado Garcia, B. R.; Mellenthin, J. D.; Melo, M.; Meloni, F.; Melzer, A.; Menary, S. B.; Meng, L.; Meng, X. T.; Mengarelli, A.; Menke, S.; Meoni, E.; Mergelmeyer, S.; Merlassino, C.; Mermod, P.; Merola, L.; Meroni, C.; Merritt, F. S.; Messina, A.; Metcalfe, J.; Mete, A. S.; Meyer, C.; Meyer, J.-P.; Meyer, J.; Meyer Zu Theenhausen, H.; Miano, F.; Middleton, R. P.; Miglioranzi, S.; Mijović, L.; Mikenberg, G.; Mikestikova, M.; Mikuž, M.; Milesi, M.; Milic, A.; Millar, D. A.; Miller, D. W.; Milov, A.; Milstead, D. A.; Minaenko, A. A.; Minashvili, I. A.; Mincer, A. I.; Mindur, B.; Mineev, M.; Minegishi, Y.; Ming, Y.; Mir, L. M.; Mirto, A.; Mistry, K. P.; Mitani, T.; Mitrevski, J.; Mitsou, V. A.; Miucci, A.; Miyagawa, P. S.; Mizukami, A.; Mjörnmark, J. U.; Mkrtchyan, T.; Mlynarikova, M.; Moa, T.; Mochizuki, K.; Mogg, P.; Mohapatra, S.; Molander, S.; Moles-Valls, R.; Mondragon, M. C.; Mönig, K.; Monk, J.; Monnier, E.; Montalbano, A.; Montejo Berlingen, J.; Monticelli, F.; Monzani, S.; Moore, R. W.; Morange, N.; Moreno, D.; Moreno Llácer, M.; Morettini, P.; Morgenstern, M.; Morgenstern, S.; Mori, D.; Mori, T.; Morii, M.; Morinaga, M.; Morisbak, V.; Morley, A. K.; Mornacchi, G.; Morris, J. D.; Morvaj, L.; Moschovakos, P.; Mosidze, M.; Moss, H. J.; Moss, J.; Motohashi, K.; Mount, R.; Mountricha, E.; Moyse, E. J. W.; Muanza, S.; Mueller, F.; Mueller, J.; Mueller, R. S. P.; Muenstermann, D.; Mullen, P.; Mullier, G. A.; Munoz Sanchez, F. J.; Murin, P.; Murray, W. J.; Murrone, A.; Muškinja, M.; Mwewa, C.; Myagkov, A. G.; Myers, J.; Myska, M.; Nachman, B. P.; Nackenhorst, O.; Nagai, K.; Nagai, R.; Nagano, K.; Nagasaka, Y.; Nagata, K.; Nagel, M.; Nagy, E.; Nairz, A. M.; Nakahama, Y.; Nakamura, K.; Nakamura, T.; Nakano, I.; Naranjo Garcia, R. F.; Narayan, R.; Narrias Villar, D. I.; Naryshkin, I.; Naumann, T.; Navarro, G.; Nayyar, R.; Neal, H. A.; Nechaeva, P. Yu.; Neep, T. J.; Negri, A.; Negrini, M.; Nektarijevic, S.; Nellist, C.; Nelson, M. E.; Nemecek, S.; Nemethy, P.; Nessi, M.; Neubauer, M. S.; Neumann, M.; Newman, P. R.; Ng, T. Y.; Ng, Y. S.; Nguyen Manh, T.; Nickerson, R. B.; Nicolaidou, R.; Nielsen, J.; Nikiforou, N.; Nikolaenko, V.; Nikolic-Audit, I.; Nikolopoulos, K.; Nilsson, P.; Ninomiya, Y.; Nisati, A.; Nishu, N.; Nisius, R.; Nitsche, I.; Nitta, T.; Nobe, T.; Noguchi, Y.; Nomachi, M.; Nomidis, I.; Nomura, M. A.; Nooney, T.; Nordberg, M.; Norjoharuddeen, N.; Novgorodova, O.; Novotny, R.; Nozaki, M.; Nozka, L.; Ntekas, K.; Nurse, E.; Nuti, F.; O'Connor, K.; O'Neil, D. C.; O'Rourke, A. A.; O'Shea, V.; Oakham, F. G.; Oberlack, H.; Obermann, T.; Ocariz, J.; Ochi, A.; Ochoa, I.; Ochoa-Ricoux, J. P.; Oda, S.; Odaka, S.; Oh, A.; Oh, S. H.; Ohm, C. C.; Ohman, H.; Oide, H.; Ojeda, M. L.; Okawa, H.; Okumura, Y.; Okuyama, T.; Olariu, A.; Oleiro Seabra, L. F.; Olivares Pino, S. A.; Oliveira Damazio, D.; Oliver, J. L.; Olsson, M. J. R.; Olszewski, A.; Olszowska, J.; Onofre, A.; Onogi, K.; Onyisi, P. U. E.; Oppen, H.; Oreglia, M. J.; Oren, Y.; Orestano, D.; Orgill, E. C.; Orlando, N.; Orr, R. S.; Osculati, B.; Ospanov, R.; Otero Y Garzon, G.; Otono, H.; Ouchrif, M.; Ould-Saada, F.; Ouraou, A.; Oussoren, K. P.; Ouyang, Q.; Owen, M.; Owen, R. E.; Ozcan, V. E.; Ozturk, N.; Pachal, K.; Pacheco Pages, A.; Pacheco Rodriguez, L.; Padilla Aranda, C.; Pagan Griso, S.; Paganini, M.; Paige, F.; Palacino, G.; Palazzo, S.; Palestini, S.; Palka, M.; Pallin, D.; Panagiotopoulou, E. St.; Panagoulias, I.; Pandini, C. E.; Panduro Vazquez, J. G.; Pani, P.; Pantea, D.; Paolozzi, L.; Papadopoulou, Th. D.; Papageorgiou, K.; Paramonov, A.; Paredes Hernandez, D.; Parida, B.; Parker, A. J.; Parker, M. A.; Parker, K. A.; Parodi, F.; Parsons, J. A.; Parzefall, U.; Pascuzzi, V. R.; Pasner, J. M.; Pasqualucci, E.; Passaggio, S.; Pastore, Fr.; Pataraia, S.; Pater, J. R.; Pauly, T.; Pearson, B.; Pedraza Lopez, S.; Pedro, R.; Peleganchuk, S. V.; Penc, O.; Peng, C.; Peng, H.; Penwell, J.; Peralva, B. S.; Perego, M. M.; Perepelitsa, D. V.; Peri, F.; Perini, L.; Pernegger, H.; Perrella, S.; Peshekhonov, V. D.; Peters, K.; Peters, R. F. Y.; Petersen, B. A.; Petersen, T. C.; Petit, E.; Petridis, A.; Petridou, C.; Petroff, P.; Petrolo, E.; Petrov, M.; Petrucci, F.; Pettersson, N. E.; Peyaud, A.; Pezoa, R.; Pham, T.; Phillips, F. H.; Phillips, P. W.; Piacquadio, G.; Pianori, E.; Picazio, A.; Pickering, M. A.; Piegaia, R.; Pilcher, J. E.; Pilkington, A. D.; Pinamonti, M.; Pinfold, J. L.; Pitt, M.; Pleier, M.-A.; Pleskot, V.; Plotnikova, E.; Pluth, D.; Podberezko, P.; Poettgen, R.; Poggi, R.; Poggioli, L.; Pogrebnyak, I.; Pohl, D.; Pokharel, I.; Polesello, G.; Poley, A.; Policicchio, A.; Polifka, R.; Polini, A.; Pollard, C. S.; Polychronakos, V.; Ponomarenko, D.; Pontecorvo, L.; Popeneciu, G. A.; Portillo Quintero, D. M.; Pospisil, S.; Potamianos, K.; Potrap, I. N.; Potter, C. J.; Potti, H.; Poulsen, T.; Poveda, J.; Pozo Astigarraga, M. E.; Pralavorio, P.; Prell, S.; Price, D.; Primavera, M.; Prince, S.; Proklova, N.; Prokofiev, K.; Prokoshin, F.; Protopopescu, S.; Proudfoot, J.; Przybycien, M.; Puri, A.; Puzo, P.; Qian, J.; Qin, Y.; Quadt, A.; Queitsch-Maitland, M.; Qureshi, A.; Radeka, V.; Radhakrishnan, S. K.; Rados, P.; Ragusa, F.; Rahal, G.; Raine, J. A.; Rajagopalan, S.; Rashid, T.; Raspopov, S.; Ratti, M. G.; Rauch, D. M.; Rauscher, F.; Rave, S.; Ravinovich, I.; Rawling, J. H.; Raymond, M.; Read, A. L.; Readioff, N. P.; Reale, M.; Rebuzzi, D. M.; Redelbach, A.; Redlinger, G.; Reece, R.; Reed, R. G.; Reeves, K.; Rehnisch, L.; Reichert, J.; Reiss, A.; Rembser, C.; Ren, H.; Rescigno, M.; Resconi, S.; Resseguie, E. D.; Rettie, S.; Reynolds, E.; Rezanova, O. L.; Reznicek, P.; Richter, R.; Richter, S.; Richter-Was, E.; Ricken, O.; Ridel, M.; Rieck, P.; Riegel, C. J.; Rifki, O.; Rijssenbeek, M.; Rimoldi, A.; Rimoldi, M.; Rinaldi, L.; Ripellino, G.; Ristić, B.; Ritsch, E.; Riu, I.; Rivera Vergara, J. C.; Rizatdinova, F.; Rizvi, E.; Rizzi, C.; Roberts, R. T.; Robertson, S. H.; Robichaud-Veronneau, A.; Robinson, D.; Robinson, J. E. M.; Robson, A.; Rocco, E.; Roda, C.; Rodina, Y.; Rodriguez Bosca, S.; Rodriguez Perez, A.; Rodriguez Rodriguez, D.; Rodríguez Vera, A. M.; Roe, S.; Rogan, C. S.; Røhne, O.; Röhrig, R.; Roloff, J.; Romaniouk, A.; Romano, M.; Romano Saez, S. M.; Romero Adam, E.; Rompotis, N.; Ronzani, M.; Roos, L.; Rosati, S.; Rosbach, K.; Rose, P.; Rosien, N.-A.; Rossi, E.; Rossi, L. P.; Rossini, L.; Rosten, J. H. N.; Rosten, R.; Rotaru, M.; Rothberg, J.; Rousseau, D.; Roy, D.; Rozanov, A.; Rozen, Y.; Ruan, X.; Rubbo, F.; Rühr, F.; Ruiz-Martinez, A.; Rurikova, Z.; Rusakovich, N. A.; Russell, H. L.; Rutherfoord, J. P.; Ruthmann, N.; Rüttinger, E. M.; Ryabov, Y. F.; Rybar, M.; Rybkin, G.; Ryu, S.; Ryzhov, A.; Rzehorz, G. F.; Saavedra, A. F.; Sabato, G.; Sacerdoti, S.; Sadrozinski, H. F.-W.; Sadykov, R.; Safai Tehrani, F.; Saha, P.; Sahinsoy, M.; Saimpert, M.; Saito, M.; Saito, T.; Sakamoto, H.; Salamanna, G.; Salazar Loyola, J. E.; Salek, D.; Sales de Bruin, P. H.; Salihagic, D.; Salnikov, A.; Salt, J.; Salvatore, D.; Salvatore, F.; Salvucci, A.; Salzburger, A.; Sammel, D.; Sampsonidis, D.; Sampsonidou, D.; Sánchez, J.; Sanchez Pineda, A.; Sandaker, H.; Sander, C. O.; Sandhoff, M.; Sandoval, C.; Sankey, D. P. C.; Sannino, M.; Sano, Y.; Sansoni, A.; Santoni, C.; Santos, H.; Santoyo Castillo, I.; Sapronov, A.; Saraiva, J. G.; Sasaki, O.; Sato, K.; Sauvan, E.; Savard, P.; Savic, N.; Sawada, R.; Sawyer, C.; Sawyer, L.; Sbarra, C.; Sbrizzi, A.; Scanlon, T.; Scannicchio, D. A.; Schaarschmidt, J.; Schacht, P.; Schachtner, B. M.; Schaefer, D.; Schaefer, L.; Schaeffer, J.; Schaepe, S.; Schäfer, U.; Schaffer, A. C.; Schaile, D.; Schamberger, R. D.; Schegelsky, V. A.; Scheirich, D.; Schenck, F.; Schernau, M.; Schiavi, C.; Schier, S.; Schildgen, L. K.; Schillaci, Z. M.; Schillo, C.; Schioppa, E. J.; Schioppa, M.; Schleicher, K. E.; Schlenker, S.; Schmidt-Sommerfeld, K. R.; Schmieden, K.; Schmitt, C.; Schmitt, S.; Schmitz, S.; Schnoor, U.; Schoeffel, L.; Schoening, A.; Schopf, E.; Schott, M.; Schouwenberg, J. F. P.; Schovancova, J.; Schramm, S.; Schuh, N.; Schulte, A.; Schultz-Coulon, H.-C.; Schumacher, M.; Schumm, B. A.; Schune, Ph.; Schwartzman, A.; Schwarz, T. A.; Schweiger, H.; Schwemling, Ph.; Schwienhorst, R.; Schwindling, J.; Sciandra, A.; Sciolla, G.; Scornajenghi, M.; Scuri, F.; Scutti, F.; Scyboz, L. M.; Searcy, J.; Seema, P.; Seidel, S. C.; Seiden, A.; Seixas, J. M.; Sekhniaidze, G.; Sekhon, K.; Sekula, S. J.; Semprini-Cesari, N.; Senkin, S.; Serfon, C.; Serin, L.; Serkin, L.; Sessa, M.; Severini, H.; Šfiligoj, T.; Sforza, F.; Sfyrla, A.; Shabalina, E.; Shahinian, J. D.; Shaikh, N. W.; Shan, L. Y.; Shang, R.; Shank, J. T.; Shapiro, M.; Sharma, A. S.; Shatalov, P. B.; Shaw, K.; Shaw, S. M.; Shcherbakova, A.; Shehu, C. Y.; Shen, Y.; Sherafati, N.; Sherman, A. D.; Sherwood, P.; Shi, L.; Shimizu, S.; Shimmin, C. O.; Shimojima, M.; Shipsey, I. P. J.; Shirabe, S.; Shiyakova, M.; Shlomi, J.; Shmeleva, A.; Shoaleh Saadi, D.; Shochet, M. J.; Shojaii, S.; Shope, D. R.; Shrestha, S.; Shulga, E.; Sicho, P.; Sickles, A. M.; Sidebo, P. E.; Sideras Haddad, E.; Sidiropoulou, O.; Sidoti, A.; Siegert, F.; Sijacki, Dj.; Silva, J.; Silva, M.; Silverstein, S. B.; Simic, L.; Simion, S.; Simioni, E.; Simmons, B.; Simon, M.; Sinervo, P.; Sinev, N. B.; Sioli, M.; Siragusa, G.; Siral, I.; Sivoklokov, S. Yu.; Sjölin, J.; Skinner, M. B.; Skubic, P.; Slater, M.; Slavicek, T.; Slawinska, M.; Sliwa, K.; Slovak, R.; Smakhtin, V.; Smart, B. H.; Smiesko, J.; Smirnov, N.; Smirnov, S. Yu.; Smirnov, Y.; Smirnova, L. N.; Smirnova, O.; Smith, J. W.; Smith, M. N. K.; Smith, R. W.; Smizanska, M.; Smolek, K.; Snesarev, A. A.; Snyder, I. M.; Snyder, S.; Sobie, R.; Socher, F.; Soffa, A. M.; Soffer, A.; Søgaard, A.; Soh, D. A.; Sokhrannyi, G.; Solans Sanchez, C. A.; Solar, M.; Soldatov, E. Yu.; Soldevila, U.; Solodkov, A. A.; Soloshenko, A.; Solovyanov, O. V.; Solovyev, V.; Sommer, P.; Son, H.; Song, W.; Sopczak, A.; Sopkova, F.; Sosa, D.; Sotiropoulou, C. L.; Sottocornola, S.; Soualah, R.; Soukharev, A. M.; South, D.; Sowden, B. C.; Spagnolo, S.; Spalla, M.; Spangenberg, M.; Spanò, F.; Sperlich, D.; Spettel, F.; Spieker, T. M.; Spighi, R.; Spigo, G.; Spiller, L. A.; Spousta, M.; St. Denis, R. D.; Stabile, A.; Stamen, R.; Stamm, S.; Stanecka, E.; Stanek, R. W.; Stanescu, C.; Stanitzki, M. M.; Stapf, B. S.; Stapnes, S.; Starchenko, E. A.; Stark, G. H.; Stark, J.; Stark, S. H.; Staroba, P.; Starovoitov, P.; Stärz, S.; Staszewski, R.; Stegler, M.; Steinberg, P.; Stelzer, B.; Stelzer, H. J.; Stelzer-Chilton, O.; Stenzel, H.; Stevenson, T. J.; Stewart, G. A.; Stockton, M. C.; Stoicea, G.; Stolte, P.; Stonjek, S.; Straessner, A.; Stramaglia, M. E.; Strandberg, J.; Strandberg, S.; Strauss, M.; Strizenec, P.; Ströhmer, R.; Strom, D. M.; Stroynowski, R.; Strubig, A.; Stucci, S. A.; Stugu, B.; Styles, N. A.; Su, D.; Su, J.; Suchek, S.; Sugaya, Y.; Suk, M.; Sulin, V. V.; Sultan, D. M. S.; Sultansoy, S.; Sumida, T.; Sun, S.; Sun, X.; Suruliz, K.; Suster, C. J. E.; Sutton, M. R.; Suzuki, S.; Svatos, M.; Swiatlowski, M.; Swift, S. P.; Sydorenko, A.; Sykora, I.; Sykora, T.; Ta, D.; Tackmann, K.; Taenzer, J.; Taffard, A.; Tafirout, R.; Tahirovic, E.; Taiblum, N.; Takai, H.; Takashima, R.; Takasugi, E. H.; Takeda, K.; Takeshita, T.; Takubo, Y.; Talby, M.; Talyshev, A. A.; Tanaka, J.; Tanaka, M.; Tanaka, R.; Tanioka, R.; Tannenwald, B. B.; Tapia Araya, S.; Tapprogge, S.; Tarek Abouelfadl Mohamed, A. T.; Tarem, S.; Tarna, G.; Tartarelli, G. F.; Tas, P.; Tasevsky, M.; Tashiro, T.; Tassi, E.; Tavares Delgado, A.; Tayalati, Y.; Taylor, A. C.; Taylor, A. J.; Taylor, G. N.; Taylor, P. T. E.; Taylor, W.; Teixeira-Dias, P.; Temple, D.; Ten Kate, H.; Teng, P. K.; Teoh, J. J.; Tepel, F.; Terada, S.; Terashi, K.; Terron, J.; Terzo, S.; Testa, M.; Teuscher, R. J.; Thais, S. J.; Theveneaux-Pelzer, T.; Thiele, F.; Thomas, J. P.; Thompson, P. D.; Thompson, A. S.; Thomsen, L. A.; Thomson, E.; Tian, Y.; Ticse Torres, R. E.; Tikhomirov, V. O.; Tikhonov, Yu. A.; Timoshenko, S.; Tipton, P.; Tisserant, S.; Todome, K.; Todorova-Nova, S.; Todt, S.; Tojo, J.; Tokár, S.; Tokushuku, K.; Tolley, E.; Tomoto, M.; Tompkins, L.; Toms, K.; Tong, B.; Tornambe, P.; Torrence, E.; Torres, H.; Torró Pastor, E.; Toth, J.; Touchard, F.; Tovey, D. R.; Treado, C. J.; Trefzger, T.; Tresoldi, F.; Tricoli, A.; Trigger, I. M.; Trincaz-Duvoid, S.; Tripiana, M. F.; Trischuk, W.; Trocmé, B.; Trofymov, A.; Troncon, C.; Trovatelli, M.; Truong, L.; Trzebinski, M.; Trzupek, A.; Tsang, K. W.; Tseng, J. C.-L.; Tsiareshka, P. V.; Tsirintanis, N.; Tsiskaridze, S.; Tsiskaridze, V.; Tskhadadze, E. G.; Tsukerman, I. I.; Tsulaia, V.; Tsuno, S.; Tsybychev, D.; Tu, Y.; Tudorache, A.; Tudorache, V.; Tulbure, T. T.; Tuna, A. N.; Turchikhin, S.; Turgeman, D.; Turk Cakir, I.; Turra, R.; Tuts, P. M.; Ucchielli, G.; Ueda, I.; Ughetto, M.; Ukegawa, F.; Unal, G.; Undrus, A.; Unel, G.; Ungaro, F. C.; Unno, Y.; Uno, K.; Urban, J.; Urquijo, P.; Urrejola, P.; Usai, G.; Usui, J.; Vacavant, L.; Vacek, V.; Vachon, B.; Vadla, K. O. H.; Vaidya, A.; Valderanis, C.; Valdes Santurio, E.; Valente, M.; Valentinetti, S.; Valero, A.; Valéry, L.; Vallier, A.; Valls Ferrer, J. A.; van den Wollenberg, W.; van der Graaf, H.; van Gemmeren, P.; van Nieuwkoop, J.; van Vulpen, I.; van Woerden, M. C.; Vanadia, M.; Vandelli, W.; Vaniachine, A.; Vankov, P.; Vari, R.; Varnes, E. W.; Varni, C.; Varol, T.; Varouchas, D.; Vartapetian, A.; Varvell, K. E.; Vasquez, J. G.; Vasquez, G. A.; Vazeille, F.; Vazquez Furelos, D.; Vazquez Schroeder, T.; Veatch, J.; Vecchio, V.; Veloce, L. M.; Veloso, F.; Veneziano, S.; Ventura, A.; Venturi, M.; Venturi, N.; Vercesi, V.; Verducci, M.; Verkerke, W.; Vermeulen, A. T.; Vermeulen, J. C.; Vetterli, M. C.; Viaux Maira, N.; Viazlo, O.; Vichou, I.; Vickey, T.; Vickey Boeriu, O. E.; Viehhauser, G. H. A.; Viel, S.; Vigani, L.; Villa, M.; Villaplana Perez, M.; Vilucchi, E.; Vincter, M. G.; Vinogradov, V. B.; Vishwakarma, A.; Vittori, C.; Vivarelli, I.; Vlachos, S.; Vogel, M.; Vokac, P.; Volpi, G.; von Buddenbrock, S. E.; von Toerne, E.; Vorobel, V.; Vorobev, K.; Vos, M.; Vossebeld, J. H.; Vranjes, N.; Vranjes Milosavljevic, M.; Vrba, V.; Vreeswijk, M.; Vuillermet, R.; Vukotic, I.; Wagner, P.; Wagner, W.; Wagner-Kuhr, J.; Wahlberg, H.; Wahrmund, S.; Wakamiya, K.; Walder, J.; Walker, R.; Walkowiak, W.; Wallangen, V.; Wang, A. M.; Wang, C.; Wang, F.; Wang, H.; Wang, H.; Wang, J.; Wang, J.; Wang, Q.; Wang, R.-J.; Wang, R.; Wang, S. M.; Wang, T.; Wang, W.; Wang, W.; Wang, Z.; Wanotayaroj, C.; Warburton, A.; Ward, C. P.; Wardrope, D. R.; Washbrook, A.; Watkins, P. M.; Watson, A. T.; Watson, M. F.; Watts, G.; Watts, S.; Waugh, B. M.; Webb, A. F.; Webb, S.; Weber, M. S.; Weber, S. M.; Weber, S. A.; Webster, J. S.; Weidberg, A. R.; Weinert, B.; Weingarten, J.; Weirich, M.; Weiser, C.; Wells, P. S.; Wenaus, T.; Wengler, T.; Wenig, S.; Wermes, N.; Werner, M. D.; Werner, P.; Wessels, M.; Weston, T. D.; Whalen, K.; Whallon, N. L.; Wharton, A. M.; White, A. S.; White, A.; White, M. J.; White, R.; Whiteson, D.; Whitmore, B. W.; Wickens, F. J.; Wiedenmann, W.; Wielers, M.; Wiglesworth, C.; Wiik-Fuchs, L. A. M.; Wildauer, A.; Wilk, F.; Wilkens, H. G.; Williams, H. H.; Williams, S.; Willis, C.; Willocq, S.; Wilson, J. A.; Wingerter-Seez, I.; Winkels, E.; Winklmeier, F.; Winston, O. J.; Winter, B. T.; Wittgen, M.; Wobisch, M.; Wolf, A.; Wolf, T. M. H.; Wolff, R.; Wolter, M. W.; Wolters, H.; Wong, V. W. S.; Woods, N. L.; Worm, S. D.; Wosiek, B. K.; Wozniak, K. W.; Wu, M.; Wu, S. L.; Wu, X.; Wu, Y.; Wyatt, T. R.; Wynne, B. M.; Xella, S.; Xi, Z.; Xia, L.; Xu, D.; Xu, L.; Xu, T.; Xu, W.; Yabsley, B.; Yacoob, S.; Yajima, K.; Yallup, D. P.; Yamaguchi, D.; Yamaguchi, Y.; Yamamoto, A.; Yamanaka, T.; Yamane, F.; Yamatani, M.; Yamazaki, T.; Yamazaki, Y.; Yan, Z.; Yang, H.; Yang, H.; Yang, S.; Yang, Y.; Yang, Z.; Yao, W.-M.; Yap, Y. C.; Yasu, Y.; Yatsenko, E.; Yau Wong, K. H.; Ye, J.; Ye, S.; Yeletskikh, I.; Yigitbasi, E.; Yildirim, E.; Yorita, K.; Yoshihara, K.; Young, C.; Young, C. J. S.; Yu, J.; Yu, J.; Yuen, S. P. Y.; Yusuff, I.; Zabinski, B.; Zacharis, G.; Zaidan, R.; Zaitsev, A. M.; Zakharchuk, N.; Zalieckas, J.; Zambito, S.; Zanzi, D.; Zeitnitz, C.; Zemaityte, G.; Zeng, J. C.; Zeng, Q.; Zenin, O.; Ženiš, T.; Zerwas, D.; Zhang, D.; Zhang, D.; Zhang, F.; Zhang, G.; Zhang, H.; Zhang, J.; Zhang, L.; Zhang, L.; Zhang, M.; Zhang, P.; Zhang, R.; Zhang, R.; Zhang, X.; Zhang, Y.; Zhang, Z.; Zhao, X.; Zhao, Y.; Zhao, Z.; Zhemchugov, A.; Zhou, B.; Zhou, C.; Zhou, L.; Zhou, M.; Zhou, M.; Zhou, N.; Zhou, Y.; Zhu, C. G.; Zhu, H.; Zhu, J.; Zhu, Y.; Zhuang, X.; Zhukov, K.; Zhulanov, V.; Zibell, A.; Zieminska, D.; Zimine, N. I.; Zimmermann, S.; Zinonos, Z.; Zinser, M.; Ziolkowski, M.; Živković, L.; Zobernig, G.; Zoccoli, A.; Zou, R.; Zur Nedden, M.; Zwalinski, L.; Atlas Collaboration

    2018-04-01

    A search for the associated production of the Higgs boson with a top quark pair (t t ¯H ) is reported. The search is performed in multilepton final states using a data set corresponding to an integrated luminosity of 36.1 fb-1 of proton-proton collision data recorded by the ATLAS experiment at a center-of-mass energy √{s }=13 TeV at the Large Hadron Collider. Higgs boson decays to W W*, τ τ , and Z Z* are targeted. Seven final states, categorized by the number and flavor of charged-lepton candidates, are examined for the presence of the Standard Model Higgs boson with a mass of 125 GeV and a pair of top quarks. An excess of events over the expected background from Standard Model processes is found with an observed significance of 4.1 standard deviations, compared to an expectation of 2.8 standard deviations. The best fit for the t t ¯H production cross section is σ (t t ¯H )=79 0-210+230 fb , in agreement with the Standard Model prediction of 50 7-50+35 fb . The combination of this result with other t t ¯H searches from the ATLAS experiment using the Higgs boson decay modes to b b ¯, γ γ and Z Z*→4 ℓ, has an observed significance of 4.2 standard deviations, compared to an expectation of 3.8 standard deviations. This provides evidence for the t t ¯H production mode.

  20. Evaluation of atmospheric profiles derived from single- and zero-difference excess phase processing of BeiDou radio occultation data from the FY-3C GNOS mission

    NASA Astrophysics Data System (ADS)

    Bai, Weihua; Liu, Congliang; Meng, Xiangguang; Sun, Yueqiang; Kirchengast, Gottfried; Du, Qifei; Wang, Xianyi; Yang, Guanglin; Liao, Mi; Yang, Zhongdong; Zhao, Danyang; Xia, Junming; Cai, Yuerong; Liu, Lijun; Wang, Dongwei

    2018-02-01

    The Global Navigation Satellite System (GNSS) Occultation Sounder (GNOS) is one of the new-generation payloads onboard the Chinese FengYun 3 (FY-3) series of operational meteorological satellites for sounding the Earth's neutral atmosphere and ionosphere. The GNOS was designed for acquiring setting and rising radio occultation (RO) data by using GNSS signals from both the Chinese BeiDou System (BDS) and the US Global Positioning System (GPS). An ultra-stable oscillator with 1 s stability (Allan deviation) at the level of 10-12 was installed on the FY-3C GNOS, and thus both zero-difference and single-difference excess phase processing methods should be feasible for FY-3C GNOS observations. In this study we focus on evaluating zero-difference processing of BDS RO data vs. single-difference processing, in order to investigate the zero-difference feasibility for this new instrument, which after its launch in September 2013 started to use BDS signals from five geostationary orbit (GEO) satellites, five inclined geosynchronous orbit (IGSO) satellites and four medium Earth orbit (MEO) satellites. We used a 3-month set of GNOS BDS RO data (October to December 2013) for the evaluation and compared atmospheric bending angle and refractivity profiles, derived from single- and zero-difference excess phase data, against co-located profiles from European Centre for Medium-Range Weather Forecasts (ECMWF) analyses. We also compared against co-located refractivity profiles from radiosondes. The statistical evaluation against these reference data shows that the results from single- and zero-difference processing are reasonably consistent in both bias and standard deviation, clearly demonstrating the feasibility of zero differencing for GNOS BDS RO observations. The average bias (and standard deviation) of the bending angle and refractivity profiles were found to be about 0.05 to 0.2 % (and 0.7 to 1.6 %) over the upper troposphere and lower stratosphere. Zero differencing was found to perform slightly better, as may be expected from its lower vulnerability to noise. The validation results indicate that GNOS can provide, on top of GPS RO profiles, accurate and precise BDS RO profiles both from single- and zero-difference processing. The GNOS observations by the series of FY-3 satellites are thus expected to provide important contributions to numerical weather prediction and global climate change analysis.

  1. WASP (Write a Scientific Paper) using Excel -5: Quartiles and standard deviation.

    PubMed

    Grech, Victor

    2018-03-01

    The almost inevitable descriptive statistics exercise that is undergone once data collection is complete, prior to inferential statistics, requires the acquisition of basic descriptors which may include standard deviation and quartiles. This paper provides pointers as to how to do this in Microsoft Excel™ and explains the relationship between the two. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. Validation Test Report for GDEM4

    DTIC Science & Technology

    2010-08-19

    standard deviations called the Generalized Digital Environmental Model ( GDEM ). The present document describes the development and evaluation of GDEM4...the newest version of GDEM . As part of the evaluation of GDEM4, comparisons are made in this report to GDEM3 and to four other ocean climatologies...depth climatology of temperature and salinity and their standard deviations called the Generalized Digital Environmental Model ( GDEM ). The history of

  3. 40 CFR 91.508 - Cumulative Sum (CumSum) procedure.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... family may be determined to be in noncompliance for purposes of § 91.510. H = The Action Limit. It is 5.0 × σ, and is a function of the standard deviation, σ. σ = is the sample standard deviation and is... Equation must be final deteriorated test results as defined in § 91.509(c). Ci = max[0 0R (Ci-1 + Xi − (FEL...

  4. Modeling the Zeeman effect in high altitude SSMIS channels for numerical weather prediction profiles: comparing a fast model and a line-by-line model

    NASA Astrophysics Data System (ADS)

    Larsson, R.; Milz, M.; Rayer, P.; Saunders, R.; Bell, W.; Booton, A.; Buehler, S. A.; Eriksson, P.; John, V.

    2015-10-01

    We present a comparison of a reference and a fast radiative transfer model using numerical weather prediction profiles for the Zeeman-affected high altitude Special Sensor Microwave Imager/Sounder channels 19-22. We find that the models agree well for channels 21 and 22 compared to the channels' system noise temperatures (1.9 and 1.3 K, respectively) and the expected profile errors at the affected altitudes (estimated to be around 5 K). For channel 22 there is a 0.5 K average difference between the models, with a standard deviation of 0.24 K for the full set of atmospheric profiles. Same channel, there is 1.2 K in average between the fast model and the sensor measurement, with 1.4 K standard deviation. For channel 21 there is a 0.9 K average difference between the models, with a standard deviation of 0.56 K. Same channel, there is 1.3 K in average between the fast model and the sensor measurement, with 2.4 K standard deviation. We consider the relatively small model differences as a validation of the fast Zeeman effect scheme for these channels. Both channels 19 and 20 have smaller average differences between the models (at below 0.2 K) and smaller standard deviations (at below 0.4 K) when both models use a two-dimensional magnetic field profile. However, when the reference model is switched to using a full three-dimensional magnetic field profile, the standard deviation to the fast model is increased to almost 2 K due to viewing geometry dependencies causing up to ± 7 K differences near the equator. The average differences between the two models remain small despite changing magnetic field configurations. We are unable to compare channels 19 and 20 to sensor measurements due to limited altitude range of the numerical weather prediction profiles. We recommended that numerical weather prediction software using the fast model takes the available fast Zeeman scheme into account for data assimilation of the affected sensor channels to better constrain the upper atmospheric temperatures.

  5. Modeling the Zeeman effect in high-altitude SSMIS channels for numerical weather prediction profiles: comparing a fast model and a line-by-line model

    NASA Astrophysics Data System (ADS)

    Larsson, Richard; Milz, Mathias; Rayer, Peter; Saunders, Roger; Bell, William; Booton, Anna; Buehler, Stefan A.; Eriksson, Patrick; John, Viju O.

    2016-03-01

    We present a comparison of a reference and a fast radiative transfer model using numerical weather prediction profiles for the Zeeman-affected high-altitude Special Sensor Microwave Imager/Sounder channels 19-22. We find that the models agree well for channels 21 and 22 compared to the channels' system noise temperatures (1.9 and 1.3 K, respectively) and the expected profile errors at the affected altitudes (estimated to be around 5 K). For channel 22 there is a 0.5 K average difference between the models, with a standard deviation of 0.24 K for the full set of atmospheric profiles. Concerning the same channel, there is 1.2 K on average between the fast model and the sensor measurement, with 1.4 K standard deviation. For channel 21 there is a 0.9 K average difference between the models, with a standard deviation of 0.56 K. Regarding the same channel, there is 1.3 K on average between the fast model and the sensor measurement, with 2.4 K standard deviation. We consider the relatively small model differences as a validation of the fast Zeeman effect scheme for these channels. Both channels 19 and 20 have smaller average differences between the models (at below 0.2 K) and smaller standard deviations (at below 0.4 K) when both models use a two-dimensional magnetic field profile. However, when the reference model is switched to using a full three-dimensional magnetic field profile, the standard deviation to the fast model is increased to almost 2 K due to viewing geometry dependencies, causing up to ±7 K differences near the equator. The average differences between the two models remain small despite changing magnetic field configurations. We are unable to compare channels 19 and 20 to sensor measurements due to limited altitude range of the numerical weather prediction profiles. We recommended that numerical weather prediction software using the fast model takes the available fast Zeeman scheme into account for data assimilation of the affected sensor channels to better constrain the upper atmospheric temperatures.

  6. Host model uncertainties in aerosol radiative forcing estimates: results from the AeroCom Prescribed intercomparison study

    NASA Astrophysics Data System (ADS)

    Stier, P.; Schutgens, N. A. J.; Bellouin, N.; Bian, H.; Boucher, O.; Chin, M.; Ghan, S.; Huneeus, N.; Kinne, S.; Lin, G.; Ma, X.; Myhre, G.; Penner, J. E.; Randles, C. A.; Samset, B.; Schulz, M.; Takemura, T.; Yu, F.; Yu, H.; Zhou, C.

    2013-03-01

    Simulated multi-model "diversity" in aerosol direct radiative forcing estimates is often perceived as a measure of aerosol uncertainty. However, current models used for aerosol radiative forcing calculations vary considerably in model components relevant for forcing calculations and the associated "host-model uncertainties" are generally convoluted with the actual aerosol uncertainty. In this AeroCom Prescribed intercomparison study we systematically isolate and quantify host model uncertainties on aerosol forcing experiments through prescription of identical aerosol radiative properties in twelve participating models. Even with prescribed aerosol radiative properties, simulated clear-sky and all-sky aerosol radiative forcings show significant diversity. For a purely scattering case with globally constant optical depth of 0.2, the global-mean all-sky top-of-atmosphere radiative forcing is -4.47 Wm-2 and the inter-model standard deviation is 0.55 Wm-2, corresponding to a relative standard deviation of 12%. For a case with partially absorbing aerosol with an aerosol optical depth of 0.2 and single scattering albedo of 0.8, the forcing changes to 1.04 Wm-2, and the standard deviation increases to 1.01 W-2, corresponding to a significant relative standard deviation of 97%. However, the top-of-atmosphere forcing variability owing to absorption (subtracting the scattering case from the case with scattering and absorption) is low, with absolute (relative) standard deviations of 0.45 Wm-2 (8%) clear-sky and 0.62 Wm-2 (11%) all-sky. Scaling the forcing standard deviation for a purely scattering case to match the sulfate radiative forcing in the AeroCom Direct Effect experiment demonstrates that host model uncertainties could explain about 36% of the overall sulfate forcing diversity of 0.11 Wm-2 in the AeroCom Direct Radiative Effect experiment. Host model errors in aerosol radiative forcing are largest in regions of uncertain host model components, such as stratocumulus cloud decks or areas with poorly constrained surface albedos, such as sea ice. Our results demonstrate that host model uncertainties are an important component of aerosol forcing uncertainty that require further attention.

  7. Quantifying the heterogeneity of the tectonic stress field using borehole data

    USGS Publications Warehouse

    Schoenball, Martin; Davatzes, Nicholas C.

    2017-01-01

    The heterogeneity of the tectonic stress field is a fundamental property which influences earthquake dynamics and subsurface engineering. Self-similar scaling of stress heterogeneities is frequently assumed to explain characteristics of earthquakes such as the magnitude-frequency relation. However, observational evidence for such scaling of the stress field heterogeneity is scarce.We analyze the local stress orientations using image logs of two closely spaced boreholes in the Coso Geothermal Field with sub-vertical and deviated trajectories, respectively, each spanning about 2 km in depth. Both the mean and the standard deviation of stress orientation indicators (borehole breakouts, drilling-induced fractures and petal-centerline fractures) determined from each borehole agree to the limit of the resolution of our method although measurements at specific depths may not. We find that the standard deviation in these boreholes strongly depends on the interval length analyzed, generally increasing up to a wellbore log length of about 600 m and constant for longer intervals. We find the same behavior in global data from the World Stress Map. This suggests that the standard deviation of stress indicators characterizes the heterogeneity of the tectonic stress field rather than the quality of the stress measurement. A large standard deviation of a stress measurement might be an expression of strong crustal heterogeneity rather than of an unreliable stress determination. Robust characterization of stress heterogeneity requires logs that sample stress indicators along a representative sample volume of at least 1 km.

  8. Dynamic Modeling and Interactive Performance of PARM: A Parallel Upper-Limb Rehabilitation Robot Using Impedance Control for Patients after Stroke.

    PubMed

    Guang, Hui; Ji, Linhong; Shi, Yingying; Misgeld, Berno J E

    2018-01-01

    The robot-assisted therapy has been demonstrated to be effective in the improvements of limb function and even activities of daily living for patients after stroke. This paper presents an interactive upper-limb rehabilitation robot with a parallel mechanism and an isometric screen embedded in the platform to display trajectories. In the dynamic modeling for impedance control, the effects of friction and inertia are reduced by introducing the principle of virtual work and derivative of Jacobian matrix. To achieve the assist-as-needed impedance control for arbitrary trajectories, the strategy based on orthogonal deviations is proposed. Simulations and experiments were performed to validate the dynamic modeling and impedance control. Besides, to investigate the influence of the impedance in practice, a subject participated in experiments and performed two types of movements with the robot, that is, rectilinear and circular movements, under four conditions, that is, with/without resistance or impedance, respectively. The results showed that the impedance and resistance affected both mean absolute error and standard deviation of movements and also demonstrated the significant differences between movements with/without impedance and resistance ( p < 0.001). Furthermore, the error patterns were discussed, which suggested that the impedance environment was capable of alleviating movement deviations by compensating the synergetic inadequacy between the shoulder and elbow joints.

  9. Dynamic Modeling and Interactive Performance of PARM: A Parallel Upper-Limb Rehabilitation Robot Using Impedance Control for Patients after Stroke

    PubMed Central

    Shi, Yingying; Misgeld, Berno J. E.

    2018-01-01

    The robot-assisted therapy has been demonstrated to be effective in the improvements of limb function and even activities of daily living for patients after stroke. This paper presents an interactive upper-limb rehabilitation robot with a parallel mechanism and an isometric screen embedded in the platform to display trajectories. In the dynamic modeling for impedance control, the effects of friction and inertia are reduced by introducing the principle of virtual work and derivative of Jacobian matrix. To achieve the assist-as-needed impedance control for arbitrary trajectories, the strategy based on orthogonal deviations is proposed. Simulations and experiments were performed to validate the dynamic modeling and impedance control. Besides, to investigate the influence of the impedance in practice, a subject participated in experiments and performed two types of movements with the robot, that is, rectilinear and circular movements, under four conditions, that is, with/without resistance or impedance, respectively. The results showed that the impedance and resistance affected both mean absolute error and standard deviation of movements and also demonstrated the significant differences between movements with/without impedance and resistance (p < 0.001). Furthermore, the error patterns were discussed, which suggested that the impedance environment was capable of alleviating movement deviations by compensating the synergetic inadequacy between the shoulder and elbow joints. PMID:29850004

  10. [Effect strength variation in the single group pre-post study design: a critical review].

    PubMed

    Maier-Riehle, B; Zwingmann, C

    2000-08-01

    In Germany, studies in rehabilitation research--in particular evaluation studies and examinations of quality of outcome--have so far mostly been executed according to the uncontrolled one-group pre-post design. Assessment of outcome is usually made by comparing the pre- and post-treatment means of the outcome variables. The pre-post differences are checked, and in case of significance, the results are increasingly presented in form of effect sizes. For this reason, this contribution presents different effect size indices used for the one-group pre-post design--in spite of fundamental doubts which exist in relation to that design due to its limited internal validity. The numerator concerning all effect size indices of the one-group pre-post design is defined as difference between the pre- and post-treatment means, whereas there are different possibilities and recommendations with regard to the denominator and hence the standard deviation that serves as the basis for standardizing the difference of the means. Used above all are standardization oriented towards the standard deviation of the pre-treatment scores, standardization oriented towards the pooled standard deviation of the pre- and post-treatment scores, and standardization oriented towards the standard deviation of the pre-post differences. Two examples are given to demonstrate that the different modes of calculating effect size indices in the one-group pre-post design may lead to very different outcome patterns. Additionally, it is pointed out that effect sizes from the uncontrolled one-group pre-post design generally tend to be higher than effect sizes from studies conducted with control groups. Finally, the pros and cons of the different effect size indices are discussed and recommendations are given.

  11. Statistical characterization of high-to-medium frequency mesoscale gravity waves by lidar-measured vertical winds and temperatures in the MLT

    NASA Astrophysics Data System (ADS)

    Lu, Xian; Chu, Xinzhao; Li, Haoyu; Chen, Cao; Smith, John A.; Vadas, Sharon L.

    2017-09-01

    We present the first statistical study of gravity waves with periods of 0.3-2.5 h that are persistent and dominant in the vertical winds measured with the University of Colorado STAR Na Doppler lidar in Boulder, CO (40.1°N, 105.2°W). The probability density functions of the wave amplitudes in temperature and vertical wind, ratios of these two amplitudes, phase differences between them, and vertical wavelengths are derived directly from the observations. The intrinsic period and horizontal wavelength of each wave are inferred from its vertical wavelength, amplitude ratio, and a designated eddy viscosity by applying the gravity wave polarization and dispersion relations. The amplitude ratios are positively correlated with the ground-based periods with a coefficient of 0.76. The phase differences between the vertical winds and temperatures (φW -φT) follow a Gaussian distribution with 84.2±26.7°, which has a much larger standard deviation than that predicted for non-dissipative waves ( 3.3°). The deviations of the observed phase differences from their predicted values for non-dissipative waves may indicate wave dissipation. The shorter-vertical-wavelength waves tend to have larger phase difference deviations, implying that the dissipative effects are more significant for shorter waves. The majority of these waves have the vertical wavelengths ranging from 5 to 40 km with a mean and standard deviation of 18.6 and 7.2 km, respectively. For waves with similar periods, multiple peaks in the vertical wavelengths are identified frequently and the ones peaking in the vertical wind are statistically longer than those peaking in the temperature. The horizontal wavelengths range mostly from 50 to 500 km with a mean and median of 180 and 125 km, respectively. Therefore, these waves are mesoscale waves with high-to-medium frequencies. Since they have recently become resolvable in high-resolution general circulation models (GCMs), this statistical study provides an important and timely reference for them.

  12. Size-dependent standard deviation for growth rates: Empirical results and theoretical modeling

    NASA Astrophysics Data System (ADS)

    Podobnik, Boris; Horvatic, Davor; Pammolli, Fabio; Wang, Fengzhong; Stanley, H. Eugene; Grosse, I.

    2008-05-01

    We study annual logarithmic growth rates R of various economic variables such as exports, imports, and foreign debt. For each of these variables we find that the distributions of R can be approximated by double exponential (Laplace) distributions in the central parts and power-law distributions in the tails. For each of these variables we further find a power-law dependence of the standard deviation σ(R) on the average size of the economic variable with a scaling exponent surprisingly close to that found for the gross domestic product (GDP) [Phys. Rev. Lett. 81, 3275 (1998)]. By analyzing annual logarithmic growth rates R of wages of 161 different occupations, we find a power-law dependence of the standard deviation σ(R) on the average value of the wages with a scaling exponent β≈0.14 close to those found for the growth of exports, imports, debt, and the growth of the GDP. In contrast to these findings, we observe for payroll data collected from 50 states of the USA that the standard deviation σ(R) of the annual logarithmic growth rate R increases monotonically with the average value of payroll. However, also in this case we observe a power-law dependence of σ(R) on the average payroll with a scaling exponent β≈-0.08 . Based on these observations we propose a stochastic process for multiple cross-correlated variables where for each variable (i) the distribution of logarithmic growth rates decays exponentially in the central part, (ii) the distribution of the logarithmic growth rate decays algebraically in the far tails, and (iii) the standard deviation of the logarithmic growth rate depends algebraically on the average size of the stochastic variable.

  13. Effect of extreme sea surface temperature events on the demography of an age-structured albatross population.

    PubMed

    Pardo, Deborah; Jenouvrier, Stéphanie; Weimerskirch, Henri; Barbraud, Christophe

    2017-06-19

    Climate changes include concurrent changes in environmental mean, variance and extremes, and it is challenging to understand their respective impact on wild populations, especially when contrasted age-dependent responses to climate occur. We assessed how changes in mean and standard deviation of sea surface temperature (SST), frequency and magnitude of warm SST extreme climatic events (ECE) influenced the stochastic population growth rate log( λ s ) and age structure of a black-browed albatross population. For changes in SST around historical levels observed since 1982, changes in standard deviation had a larger (threefold) and negative impact on log( λ s ) compared to changes in mean. By contrast, the mean had a positive impact on log( λ s ). The historical SST mean was lower than the optimal SST value for which log( λ s ) was maximized. Thus, a larger environmental mean increased the occurrence of SST close to this optimum that buffered the negative effect of ECE. This 'climate safety margin' (i.e. difference between optimal and historical climatic conditions) and the specific shape of the population growth rate response to climate for a species determine how ECE affect the population. For a wider range in SST, both the mean and standard deviation had negative impact on log( λ s ), with changes in the mean having a greater effect than the standard deviation. Furthermore, around SST historical levels increases in either mean or standard deviation of the SST distribution led to a younger population, with potentially important conservation implications for black-browed albatrosses.This article is part of the themed issue 'Behavioural, ecological and evolutionary responses to extreme climatic events'. © 2017 The Author(s).

  14. Is standard deviation of daily PM2.5 concentration associated with respiratory mortality?

    PubMed

    Lin, Hualiang; Ma, Wenjun; Qiu, Hong; Vaughn, Michael G; Nelson, Erik J; Qian, Zhengmin; Tian, Linwei

    2016-09-01

    Studies on health effects of air pollution often use daily mean concentration to estimate exposure while ignoring daily variations. This study examined the health effects of daily variation of PM2.5. We calculated daily mean and standard deviations of PM2.5 in Hong Kong between 1998 and 2011. We used a generalized additive model to estimate the association between respiratory mortality and daily mean and variation of PM2.5, as well as their interaction. We controlled for potential confounders, including temporal trends, day of the week, meteorological factors, and gaseous air pollutants. Both daily mean and standard deviation of PM2.5 were significantly associated with mortalities from overall respiratory diseases and pneumonia. Each 10 μg/m(3) increment in daily mean concentration at lag 2 day was associated with a 0.61% (95% CI: 0.19%, 1.03%) increase in overall respiratory mortality and a 0.67% (95% CI: 0.14%, 1.21%) increase in pneumonia mortality. And a 10 μg/m(3) increase in standard deviation at lag 1 day corresponded to a 1.40% (95% CI: 0.35%, 2.46%) increase in overall respiratory mortality, and a 1.80% (95% CI: 0.46%, 3.16%) increase in pneumonia mortality. We also observed a positive but non-significant synergistic interaction between daily mean and variation on respiratory mortality and pneumonia mortality. However, we did not find any significant association with mortality from chronic obstructive pulmonary diseases. Our study suggests that, besides mean concentration, the standard deviation of PM2.5 might be one potential predictor of respiratory mortality in Hong Kong, and should be considered when assessing the respiratory effects of PM2.5. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Assessment issues in the testing of children at school entry.

    PubMed

    Rock, Donald A; Stenner, A Jackson

    2005-01-01

    The authors introduce readers to the research documenting racial and ethnic gaps in school readiness. They describe the key tests, including the Peabody Picture Vocabulary Test (PPVT), the Early Childhood Longitudinal Study (ECLS), and several intelligence tests, and describe how they have been administered to several important national samples of children. Next, the authors review the different estimates of the gaps and discuss how to interpret these differences. In interpreting test results, researchers use the statistical term "standard deviation" to compare scores across the tests. On average, the tests find a gap of about 1 standard deviation. The ECLS-K estimate is the lowest, about half a standard deviation. The PPVT estimate is the highest, sometimes more than 1 standard deviation. When researchers adjust those gaps statistically to take into account different outside factors that might affect children's test scores, such as family income or home environment, the gap narrows but does not disappear. Why such different estimates of the gap? The authors consider explanations such as differences in the samples, racial or ethnic bias in the tests, and whether the tests reflect different aspects of school "readiness," and conclude that none is likely to explain the varying estimates. Another possible explanation is the Spearman Hypothesis-that all tests are imperfect measures of a general ability construct, g; the more highly a given test correlates with g, the larger the gap will be. But the Spearman Hypothesis, too, leaves questions to be investigated. A gap of 1 standard deviation may not seem large, but the authors show clearly how it results in striking disparities in the performance of black and white students and why it should be of serious concern to policymakers.

  16. Improving IQ measurement in intellectual disabilities using true deviation from population norms

    PubMed Central

    2014-01-01

    Background Intellectual disability (ID) is characterized by global cognitive deficits, yet the very IQ tests used to assess ID have limited range and precision in this population, especially for more impaired individuals. Methods We describe the development and validation of a method of raw z-score transformation (based on general population norms) that ameliorates floor effects and improves the precision of IQ measurement in ID using the Stanford Binet 5 (SB5) in fragile X syndrome (FXS; n = 106), the leading inherited cause of ID, and in individuals with idiopathic autism spectrum disorder (ASD; n = 205). We compared the distributional characteristics and Q-Q plots from the standardized scores with the deviation z-scores. Additionally, we examined the relationship between both scoring methods and multiple criterion measures. Results We found evidence that substantial and meaningful variation in cognitive ability on standardized IQ tests among individuals with ID is lost when converting raw scores to standardized scaled, index and IQ scores. Use of the deviation z- score method rectifies this problem, and accounts for significant additional variance in criterion validation measures, above and beyond the usual IQ scores. Additionally, individual and group-level cognitive strengths and weaknesses are recovered using deviation scores. Conclusion Traditional methods for generating IQ scores in lower functioning individuals with ID are inaccurate and inadequate, leading to erroneously flat profiles. However assessment of cognitive abilities is substantially improved by measuring true deviation in performance from standardization sample norms. This work has important implications for standardized test development, clinical assessment, and research for which IQ is an important measure of interest in individuals with neurodevelopmental disorders and other forms of cognitive impairment. PMID:26491488

  17. Size-dependent standard deviation for growth rates: empirical results and theoretical modeling.

    PubMed

    Podobnik, Boris; Horvatic, Davor; Pammolli, Fabio; Wang, Fengzhong; Stanley, H Eugene; Grosse, I

    2008-05-01

    We study annual logarithmic growth rates R of various economic variables such as exports, imports, and foreign debt. For each of these variables we find that the distributions of R can be approximated by double exponential (Laplace) distributions in the central parts and power-law distributions in the tails. For each of these variables we further find a power-law dependence of the standard deviation sigma(R) on the average size of the economic variable with a scaling exponent surprisingly close to that found for the gross domestic product (GDP) [Phys. Rev. Lett. 81, 3275 (1998)]. By analyzing annual logarithmic growth rates R of wages of 161 different occupations, we find a power-law dependence of the standard deviation sigma(R) on the average value of the wages with a scaling exponent beta approximately 0.14 close to those found for the growth of exports, imports, debt, and the growth of the GDP. In contrast to these findings, we observe for payroll data collected from 50 states of the USA that the standard deviation sigma(R) of the annual logarithmic growth rate R increases monotonically with the average value of payroll. However, also in this case we observe a power-law dependence of sigma(R) on the average payroll with a scaling exponent beta approximately -0.08 . Based on these observations we propose a stochastic process for multiple cross-correlated variables where for each variable (i) the distribution of logarithmic growth rates decays exponentially in the central part, (ii) the distribution of the logarithmic growth rate decays algebraically in the far tails, and (iii) the standard deviation of the logarithmic growth rate depends algebraically on the average size of the stochastic variable.

  18. Improving IQ measurement in intellectual disabilities using true deviation from population norms.

    PubMed

    Sansone, Stephanie M; Schneider, Andrea; Bickel, Erika; Berry-Kravis, Elizabeth; Prescott, Christina; Hessl, David

    2014-01-01

    Intellectual disability (ID) is characterized by global cognitive deficits, yet the very IQ tests used to assess ID have limited range and precision in this population, especially for more impaired individuals. We describe the development and validation of a method of raw z-score transformation (based on general population norms) that ameliorates floor effects and improves the precision of IQ measurement in ID using the Stanford Binet 5 (SB5) in fragile X syndrome (FXS; n = 106), the leading inherited cause of ID, and in individuals with idiopathic autism spectrum disorder (ASD; n = 205). We compared the distributional characteristics and Q-Q plots from the standardized scores with the deviation z-scores. Additionally, we examined the relationship between both scoring methods and multiple criterion measures. We found evidence that substantial and meaningful variation in cognitive ability on standardized IQ tests among individuals with ID is lost when converting raw scores to standardized scaled, index and IQ scores. Use of the deviation z- score method rectifies this problem, and accounts for significant additional variance in criterion validation measures, above and beyond the usual IQ scores. Additionally, individual and group-level cognitive strengths and weaknesses are recovered using deviation scores. Traditional methods for generating IQ scores in lower functioning individuals with ID are inaccurate and inadequate, leading to erroneously flat profiles. However assessment of cognitive abilities is substantially improved by measuring true deviation in performance from standardization sample norms. This work has important implications for standardized test development, clinical assessment, and research for which IQ is an important measure of interest in individuals with neurodevelopmental disorders and other forms of cognitive impairment.

  19. Validation of 10 years of SAO OMI Ozone Profiles with Ozonesonde and MLS Observations

    NASA Astrophysics Data System (ADS)

    Huang, G.; Liu, X.; Chance, K.; Bhartia, P. K.

    2015-12-01

    To evaluate the accuracy and long-term stability of the SAO OMI ozone profile product, we validate ~10 years of ozone profile product (Oct. 2004-Dec. 2014) against collocated ozonesonde and MLS data. Ozone profiles as well stratospheric, tropospheric, lower tropospheric ozone columns are compared with ozonesonde data for different latitude bands, and time periods (e.g., 2004-2008/2009-2014 for without/with row anomaly. The mean biases and their standard deviations are also assessed as a function of time to evaluate the long-term stability and bias trends. In the mid-latitude and tropical regions, OMI generally shows good agreement with ozonesonde observations. The mean ozone profile biases are generally within 6% with up to 30% standard deviations. The biases of stratospheric ozone columns (SOC) and tropospheric ozone columns (TOC) are -0.3%-2.2% and -0.2%-3%, while standard deviations are 3.9%-5.8% and 14.4%-16.0%, respectively. However, the retrievals during 2009-2014 show larger standard deviations and larger temporal variations; the standard deviations increase by ~5% in the troposphere and ~2% in the stratosphere. Retrieval biases at individual levels in the stratosphere and upper troposphere show statistically significant trends and different trends for 2004-2008 and 2009-2014 periods. The trends in integrated ozone partial columns are less significant due to cancellation from various layers, except for significant trend in tropical SOC. These results suggest the need to perform time dependent radiometric calibration to maintain the long-term stability of this product. Similarly, we are comparing the OMI stratospheric ozone profiles and SOC with collocated MLS data, and the results will be reported.

  20. [The heterogeneity of blood flow on magnetic resonance imaging: a biomarker for grading cerebral astrocytomas].

    PubMed

    Revert Ventura, A J; Sanz Requena, R; Martí-Bonmatí, L; Pallardó, Y; Jornet, J; Gaspar, C

    2014-01-01

    To study whether the histograms of quantitative parameters of perfusion in MRI obtained from tumor volume and peritumor volume make it possible to grade astrocytomas in vivo. We included 61 patients with histological diagnoses of grade II, III, or IV astrocytomas who underwent T2*-weighted perfusion MRI after intravenous contrast agent injection. We manually selected the tumor volume and peritumor volume and quantified the following perfusion parameters on a voxel-by-voxel basis: blood volume (BV), blood flow (BF), mean transit time (TTM), transfer constant (K(trans)), washout coefficient, interstitial volume, and vascular volume. For each volume, we obtained the corresponding histogram with its mean, standard deviation, and kurtosis (using the standard deviation and kurtosis as measures of heterogeneity) and we compared the differences in each parameter between different grades of tumor. We also calculated the mean and standard deviation of the highest 10% of values. Finally, we performed a multiparametric discriminant analysis to improve the classification. For tumor volume, we found statistically significant differences among the three grades of tumor for the means and standard deviations of BV, BF, and K(trans), both for the entire distribution and for the highest 10% of values. For the peritumor volume, we found no significant differences for any parameters. The discriminant analysis improved the classification slightly. The quantification of the volume parameters of the entire region of the tumor with BV, BF, and K(trans) is useful for grading astrocytomas. The heterogeneity represented by the standard deviation of BF is the most reliable diagnostic parameter for distinguishing between low grade and high grade lesions. Copyright © 2011 SERAM. Published by Elsevier Espana. All rights reserved.

  1. Relationship of Hotspots to the Distribution of Surficial Surf-Zone Sediments along the Outer Banks of North Carolina

    NASA Astrophysics Data System (ADS)

    Schupp, C. A.; McNinch, J. E.; List, J. H.; Farris, A. S.

    2002-12-01

    The formation and behavior of hotspots, or sections of the beach that exhibit markedly higher shoreline change rates than adjacent regions, are poorly understood. Several hotspots have been identified on the Outer Banks, a developed barrier island in North Carolina. To better understand hotspot dynamics and the potential relationship to the geologic framework in which they occur, the surf zone between Duck and Bodie Island was surveyed in June 2002 as part of a research effort supported by the U.S. Geological Survey and U.S. Army Corps of Engineers. Swath bathymetry, sidescan sonar, and chirp seismic were used to characterize a region 40 km long and1 km wide. Hotspot locations were pinpointed using standard deviation values for shoreline position as determined by monthly SWASH buggy surveys of the mean high water contour between October 1999 and September 2002. Observational data and sidescan images were mapped to delineate regions of surficial sediment distributions, and regions of interest were ground-truthed via grab samples or visual inspection. General kilometer-scale correlation between acoustic backscatter and high shoreline standard deviation is evident. Acoustic returns are uniform in a region of Duck where standard deviation is low, but backscatter is patchy around the Kitty Hawk hotspot, where standard deviation is higher. Based on ground-truthing of an area further north, these patches are believed to be an older ravinement surface of fine sediment. More detailed analyses of the correlation between acoustic data, standard deviation, and hotspot locations will be presented. Future work will include integration of seismic, bathymetric, and sidescan data to better understand the links between sub-bottom geology, temporal changes in surficial sediments, surf-zone sediment budgets, and short-term changes in shoreline position and morphology.

  2. Comparison of isolated-check visual evoked potential and standard automated perimetry in early glaucoma and high-risk ocular hypertension

    PubMed Central

    Chen, Xiang-Wu; Zhao, Ying-Xi

    2017-01-01

    AIM To compare the diagnostic performance of isolated-check visual evoked potential (icVEP) and standard automated perimetry (SAP), for evaluating the application values of icVEP in the detection of early glaucoma. METHODS Totally 144 subjects (288 eyes) were enrolled in this study. icVEP testing was performed with the Neucodia visual electrophysiological diagnostic system. A 15% positive-contrast (bright) condition pattern was used in this device to differentiate between glaucoma patients and healthy control subjects. Signal-to-noise ratios (SNR) were derived based on a multivariate statistic. The eyes were judged as abnormal if the test yielded an SNR≤1. SAP testing was performed with the Humphrey Field Analyzer II. The visual fields were deemed as abnormality if the glaucoma hemifield test results outside normal limits; or the pattern standard deviation with P<0.05; or the cluster of three or more non-edge points on the pattern deviation plot in a single hemifield with P<0.05, one of which must have a P<0.01. Disc photographs were graded as either glaucomatous optic neuropathy or normal by two experts who were masked to all other patient information. Moorfields regression analysis (MRA) used as a separate diagnostic classification was performed by Heidelberg retina tomograph (HRT). RESULTS When the disc photograph grader was used as diagnostic standard, the sensitivity for SAP and icVEP was 32.3% and 38.5% respectively and specificity was 82.3% and 77.8% respectively. When the MRA Classifier was used as the diagnostic standard, the sensitivity for SAP and icVEP was 48.6% and 51.4% respectively and specificity was 84.1% and 78.0% respectively. When the combined structural assessment was used as the diagnostic standard, the sensitivity for SAP and icVEP was 59.2% and 53.1% respectively and specificity was 84.2% and 84.6% respectivlely. There was no statistical significance between the sensitivity or specificity of SAP and icVEP, regardless of which diagnostic standard was based on. CONCLUSION The diagnostic performance of icVEP is not better than that of SAP in the detection of early glaucoma. PMID:28503434

  3. Georeferencing UAS Derivatives Through Point Cloud Registration with Archived Lidar Datasets

    NASA Astrophysics Data System (ADS)

    Magtalas, M. S. L. Y.; Aves, J. C. L.; Blanco, A. C.

    2016-10-01

    Georeferencing gathered images is a common step before performing spatial analysis and other processes on acquired datasets using unmanned aerial systems (UAS). Methods of applying spatial information to aerial images or their derivatives is through onboard GPS (Global Positioning Systems) geotagging, or through tying of models through GCPs (Ground Control Points) acquired in the field. Currently, UAS (Unmanned Aerial System) derivatives are limited to meter-levels of accuracy when their generation is unaided with points of known position on the ground. The use of ground control points established using survey-grade GPS or GNSS receivers can greatly reduce model errors to centimeter levels. However, this comes with additional costs not only with instrument acquisition and survey operations, but also in actual time spent in the field. This study uses a workflow for cloud-based post-processing of UAS data in combination with already existing LiDAR data. The georeferencing of the UAV point cloud is executed using the Iterative Closest Point algorithm (ICP). It is applied through the open-source CloudCompare software (Girardeau-Montaut, 2006) on a `skeleton point cloud'. This skeleton point cloud consists of manually extracted features consistent on both LiDAR and UAV data. For this cloud, roads and buildings with minimal deviations given their differing dates of acquisition are considered consistent. Transformation parameters are computed for the skeleton cloud which could then be applied to the whole UAS dataset. In addition, a separate cloud consisting of non-vegetation features automatically derived using CANUPO classification algorithm (Brodu and Lague, 2012) was used to generate a separate set of parameters. Ground survey is done to validate the transformed cloud. An RMSE value of around 16 centimeters was found when comparing validation data to the models georeferenced using the CANUPO cloud and the manual skeleton cloud. Cloud-to-cloud distance computations of CANUPO and manual skeleton clouds were obtained with values for both equal to around 0.67 meters at 1.73 standard deviation.

  4. Preliminary analysis of hot spot factors in an advanced reactor for space electric power systems

    NASA Technical Reports Server (NTRS)

    Lustig, P. H.; Holms, A. G.; Davison, H. W.

    1973-01-01

    The maximum fuel pin temperature for nominal operation in an advanced power reactor is 1370 K. Because of possible nitrogen embrittlement of the clad, the fuel temperature was limited to 1622 K. Assuming simultaneous occurrence of the most adverse conditions a deterministic analysis gave a maximum fuel temperature of 1610 K. A statistical analysis, using a synthesized estimate of the standard deviation for the highest fuel pin temperature, showed probabilities of 0.015 of that pin exceeding the temperature limit by the distribution free Chebyshev inequality and virtually nil assuming a normal distribution. The latter assumption gives a 1463 K maximum temperature at 3 standard deviations, the usually assumed cutoff. Further, the distribution and standard deviation of the fuel-clad gap are the most significant contributions to the uncertainty in the fuel temperature.

  5. Influence of eye micromotions on spatially resolved refractometry

    NASA Astrophysics Data System (ADS)

    Chyzh, Igor H.; Sokurenko, Vyacheslav M.; Osipova, Irina Y.

    2001-01-01

    The influence eye micromotions on the accuracy of estimation of Zernike coefficients form eye transverse aberration measurements was investigated. By computer modeling, the following found eye aberrations have been examined: defocusing, primary astigmatism, spherical aberration of the 3rd and the 5th orders, as well as their combinations. It was determined that the standard deviation of estimated Zernike coefficients is proportional to the standard deviation of angular eye movements. Eye micromotions cause the estimation errors of Zernike coefficients of present aberrations and produce the appearance of Zernike coefficients of aberrations, absent in the eye. When solely defocusing is present, the biggest errors, cased by eye micromotions, are obtained for aberrations like coma and astigmatism. In comparison with other aberrations, spherical aberration of the 3rd and the 5th orders evokes the greatest increase of the standard deviation of other Zernike coefficients.

  6. Parameter estimation method and updating of regional prediction equations for ungaged sites in the desert region of California

    USGS Publications Warehouse

    Barth, Nancy A.; Veilleux, Andrea G.

    2012-01-01

    The U.S. Geological Survey (USGS) is currently updating at-site flood frequency estimates for USGS streamflow-gaging stations in the desert region of California. The at-site flood-frequency analysis is complicated by short record lengths (less than 20 years is common) and numerous zero flows/low outliers at many sites. Estimates of the three parameters (mean, standard deviation, and skew) required for fitting the log Pearson Type 3 (LP3) distribution are likely to be highly unreliable based on the limited and heavily censored at-site data. In a generalization of the recommendations in Bulletin 17B, a regional analysis was used to develop regional estimates of all three parameters (mean, standard deviation, and skew) of the LP3 distribution. A regional skew value of zero from a previously published report was used with a new estimated mean squared error (MSE) of 0.20. A weighted least squares (WLS) regression method was used to develop both a regional standard deviation and a mean model based on annual peak-discharge data for 33 USGS stations throughout California’s desert region. At-site standard deviation and mean values were determined by using an expected moments algorithm (EMA) method for fitting the LP3 distribution to the logarithms of annual peak-discharge data. Additionally, a multiple Grubbs-Beck (MGB) test, a generalization of the test recommended in Bulletin 17B, was used for detecting multiple potentially influential low outliers in a flood series. The WLS regression found that no basin characteristics could explain the variability of standard deviation. Consequently, a constant regional standard deviation model was selected, resulting in a log-space value of 0.91 with a MSE of 0.03 log units. Yet drainage area was found to be statistically significant at explaining the site-to-site variability in mean. The linear WLS regional mean model based on drainage area had a Pseudo- 2 R of 51 percent and a MSE of 0.32 log units. The regional parameter estimates were then used to develop a set of equations for estimating flows with 50-, 20-, 10-, 4-, 2-, 1-, 0.5-, and 0.2-percent annual exceedance probabilities for ungaged basins. The final equations are functions of drainage area.Average standard errors of prediction for these regression equations range from 214.2 to 856.2 percent.

  7. Search for the Standard Model Higgs Boson Produced through Vector Boson Fusion and Decaying to $$\\mathrm{b\\bar{b}}$$

    DOE PAGES

    Khachatryan, Vardan

    2015-08-27

    A first search is reported for a standard model Higgs boson (H) that is produced through vector boson fusion and decays to a bottom-quark pair. Two data samples, corresponding to integrated luminosities of 19.8 fb -1 and 18.3 fb -1 of proton-proton collisions at √s=8 TeV were selected for this channel at the CERN LHC. The observed significance in these data samples for a H→more » $$\\mathrm{b\\bar{b}}$$ signal at a mass of 125 GeV is 2.2 standard deviations, while the expected significance is 0.8 standard deviations. The fitted signal strength μ=σ/σ SM=2.8 +1.6 -1.4. The combination of this result with other CMS searches for the Higgs boson decaying to a b-quark pair yields a signal strength of 1.0±0.4, corresponding to a signal significance of 2.6 standard deviations for a Higgs boson mass of 125 GeV.« less

  8. Deviation Management: Key Management Subsystem Driver of Knowledge-Based Continuous Improvement in the Henry Ford Production System.

    PubMed

    Zarbo, Richard J; Copeland, Jacqueline R; Varney, Ruan C

    2017-10-01

    To develop a business subsystem fulfilling International Organization for Standardization 15189 nonconformance management regulatory standard, facilitating employee engagement in problem identification and resolution to effect quality improvement and risk mitigation. From 2012 to 2016, the integrated laboratories of the Henry Ford Health System used a quality technical team to develop and improve a management subsystem designed to identify, track, trend, and summarize nonconformances based on frequency, risk, and root cause for elimination at the level of the work. Programmatic improvements and training resulted in markedly increased documentation culminating in 71,641 deviations in 2016 classified by a taxonomy of 281 defect types into preanalytic (74.8%), analytic (23.6%), and postanalytic (1.6%) testing phases. The top 10 deviations accounted for 55,843 (78%) of the total. Deviation management is a key subsystem of managers' standard work whereby knowledge of nonconformities assists in directing corrective actions and continuous improvements that promote consistent execution and higher levels of performance. © American Society for Clinical Pathology, 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  9. [Determination of acetochlor and oxyfluorfen by capillary gas chromatography].

    PubMed

    Xiang, Wen-Sheng; Wang, Xiang-Jing; Wang, Jing; Wang, Qing

    2002-09-01

    A method is described for the determination of acetochlor and oxyfluorfen by capillary gas chromatography with FID and an SE-30 capillary column (60 m x 0.53 mm i. d., 1.5 microm), using dibutyl phthalate as the internal standard. The standard deviations for acetochlor and oxyfluorfen concentration(mass fraction) were 0.44% and 0.47% respectively. The relative standard deviations for acetochlor and oxyfluorfen were 0.79% and 0.88% and the average recoveries for acetochlor and oxyfluorfen were 99.3% and 101.1% respectively. The method is simple, rapid and accurate.

  10. U.S. Navy Marine Climatic Atlas of the World. Volume IX. World-Wide Means and Standard Deviations

    DTIC Science & Technology

    1981-10-01

    TITLE (..d SobtII,) S. TYPE OF REPORT & PERIOD COVERED U. S. Navy Marine Climatic Atlas of the World Volume IX World-wide Means and Standard Reference...Ives the best estimate of the population standard deviations. The means, , are com~nuted from: EX IIN I 90 80 70 60" 50’ 40, 30 20 10 0 1070 T- VErr ...or 10%, whichever is greater Since the mean ice limit approximates the minus two de l temperature isopleth, this analyzed lower limit was Wave Heights

  11. The normalization of deviance in healthcare delivery

    PubMed Central

    Banja, John

    2009-01-01

    Many serious medical errors result from violations of recognized standards of practice. Over time, even egregious violations of standards of practice may become “normalized” in healthcare delivery systems. This article describes what leads to this normalization and explains why flagrant practice deviations can persist for years, despite the importance of the standards at issue. This article also provides recommendations to aid healthcare organizations in identifying and managing unsafe practice deviations before they become normalized and pose genuine risks to patient safety, quality care, and employee morale. PMID:20161685

  12. Estimating Accuracy of Land-Cover Composition From Two-Stage Clustering Sampling

    EPA Science Inventory

    Land-cover maps are often used to compute land-cover composition (i.e., the proportion or percent of area covered by each class), for each unit in a spatial partition of the region mapped. We derive design-based estimators of mean deviation (MD), mean absolute deviation (MAD), ...

  13. Observation of the Higgs boson decay to a pair of τ leptons with the CMS detector

    NASA Astrophysics Data System (ADS)

    Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Ambrogi, F.; Asilar, E.; Bergauer, T.; Brandstetter, J.; Brondolin, E.; Dragicevic, M.; Erö, J.; Flechl, M.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Grossmann, J.; Hrubec, J.; Jeitler, M.; König, A.; Krammer, N.; Krätschmer, I.; Liko, D.; Madlener, T.; Mikulec, I.; Pree, E.; Rabady, D.; Rad, N.; Rohringer, H.; Schieck, J.; Schöfbeck, R.; Spanring, M.; Spitzbart, D.; Waltenberger, W.; Wittmann, J.; Wulz, C.-E.; Zarucki, M.; Chekhovsky, V.; Mossolov, V.; Suarez Gonzalez, J.; De Wolf, E. A.; Di Croce, D.; Janssen, X.; Lauwers, J.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Abu Zeid, S.; Blekman, F.; D'Hondt, J.; De Bruyn, I.; De Clercq, J.; Deroover, K.; Flouris, G.; Lontkovskyi, D.; Lowette, S.; Moortgat, S.; Moreels, L.; Python, Q.; Skovpen, K.; Tavernier, S.; Van Doninck, W.; Van Mulders, P.; Van Parijs, I.; Beghin, D.; Brun, H.; Clerbaux, B.; De Lentdecker, G.; Delannoy, H.; Fasanella, G.; Favart, L.; Goldouzian, R.; Grebenyuk, A.; Karapostoli, G.; Lenzi, T.; Luetic, J.; Maerschalk, T.; Marinov, A.; Randle-conde, A.; Seva, T.; Vander Velde, C.; Vanlaer, P.; Vannerom, D.; Yonamine, R.; Zenoni, F.; Zhang, F.; Cimmino, A.; Cornelis, T.; Dobur, D.; Fagot, A.; Gul, M.; Khvastunov, I.; Poyraz, D.; Roskas, C.; Salva, S.; Tytgat, M.; Verbeke, W.; Zaganidis, N.; Bakhshiansohi, H.; Bondu, O.; Brochet, S.; Bruno, G.; Caputo, C.; Caudron, A.; De Visscher, S.; Delaere, C.; Delcourt, M.; Francois, B.; Giammanco, A.; Jafari, A.; Komm, M.; Krintiras, G.; Lemaitre, V.; Magitteri, A.; Mertens, A.; Musich, M.; Piotrzkowski, K.; Quertenmont, L.; Vidal Marono, M.; Wertz, S.; Beliy, N.; Aldá Júnior, W. L.; Alves, F. L.; Alves, G. A.; Brito, L.; Correa Martins Junior, M.; Hensel, C.; Moraes, A.; Pol, M. E.; Rebello Teles, P.; Belchior Batista Das Chagas, E.; Carvalho, W.; Chinellato, J.; Coelho, E.; Custódio, A.; Da Costa, E. M.; Da Silveira, G. G.; De Jesus Damiao, D.; Fonseca De Souza, S.; Huertas Guativa, L. M.; Malbouisson, H.; Melo De Almeida, M.; Mora Herrera, C.; Mundim, L.; Nogima, H.; Santoro, A.; Sznajder, A.; Tonelli Manganote, E. J.; Torres Da Silva De Araujo, F.; Vilela Pereira, A.; Ahuja, S.; Bernardes, C. A.; Fernandez Perez Tomei, T. R.; Gregores, E. M.; Mercadante, P. G.; Novaes, S. F.; Padula, Sandra S.; Romero Abad, D.; Ruiz Vargas, J. C.; Aleksandrov, A.; Hadjiiska, R.; Iaydjiev, P.; Misheva, M.; Rodozov, M.; Shopova, M.; Stoykova, S.; Sultanov, G.; Dimitrov, A.; Glushkov, I.; Litov, L.; Pavlov, B.; Petkov, P.; Fang, W.; Gao, X.; Ahmad, M.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Chen, M.; Chen, Y.; Jiang, C. H.; Leggat, D.; Liao, H.; Liu, Z.; Romeo, F.; Shaheen, S. M.; Spiezia, A.; Tao, J.; Wang, C.; Wang, Z.; Yazgan, E.; Zhang, H.; Zhang, S.; Zhao, J.; Ban, Y.; Chen, G.; Li, Q.; Liu, S.; Mao, Y.; Qian, S. J.; Wang, D.; Xu, Z.; Avila, C.; Cabrera, A.; Chaparro Sierra, L. F.; Florez, C.; González Hernández, C. F.; Ruiz Alvarez, J. D.; Courbon, B.; Godinovic, N.; Lelas, D.; Puljak, I.; Ribeiro Cipriano, P. M.; Sculac, T.; Antunovic, Z.; Kovac, M.; Brigljevic, V.; Ferencek, D.; Kadija, K.; Mesic, B.; Starodumov, A.; Susa, T.; Ather, M. W.; Attikis, A.; Mavromanolakis, G.; Mousa, J.; Nicolaou, C.; Ptochos, F.; Razis, P. A.; Rykaczewski, H.; Finger, M.; Finger, M.; Carrera Jarrin, E.; Assran, Y.; Elgammal, S.; Mahrous, A.; Dewanjee, R. K.; Kadastik, M.; Perrini, L.; Raidal, M.; Tiko, A.; Veelken, C.; Eerola, P.; Pekkanen, J.; Voutilainen, M.; Härkönen, J.; Järvinen, T.; Karimäki, V.; Kinnunen, R.; Lampén, T.; Lassila-Perini, K.; Lehti, S.; Lindén, T.; Luukka, P.; Tuominen, E.; Tuominiemi, J.; Tuovinen, E.; Talvitie, J.; Tuuva, T.; Besancon, M.; Couderc, F.; Dejardin, M.; Denegri, D.; Faure, J. L.; Ferri, F.; Ganjour, S.; Ghosh, S.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Kucher, I.; Locci, E.; Machet, M.; Malcles, J.; Negro, G.; Rander, J.; Rosowsky, A.; Sahin, M. Ö.; Titov, M.; Abdulsalam, A.; Amendola, C.; Antropov, I.; Baffioni, S.; Beaudette, F.; Busson, P.; Cadamuro, L.; Charlot, C.; Granier de Cassagnac, R.; Jo, M.; Lisniak, S.; Lobanov, A.; Martin Blanco, J.; Nguyen, M.; Ochando, C.; Ortona, G.; Paganini, P.; Pigard, P.; Salerno, R.; Sauvan, J. B.; Sirois, Y.; Stahl Leiton, A. G.; Strebler, T.; Yilmaz, Y.; Zabi, A.; Zghiche, A.; Agram, J.-L.; Andrea, J.; Bloch, D.; Brom, J.-M.; Buttignol, M.; Chabert, E. C.; Chanon, N.; Collard, C.; Conte, E.; Coubez, X.; Fontaine, J.-C.; Gelé, D.; Goerlach, U.; Jansová, M.; Le Bihan, A.-C.; Tonon, N.; Van Hove, P.; Gadrat, S.; Beauceron, S.; Bernet, C.; Boudoul, G.; Chierici, R.; Contardo, D.; Depasse, P.; El Mamouni, H.; Fay, J.; Finco, L.; Gascon, S.; Gouzevitch, M.; Grenier, G.; Ille, B.; Lagarde, F.; Laktineh, I. B.; Lethuillier, M.; Mirabito, L.; Pequegnot, A. L.; Perries, S.; Popov, A.; Sordini, V.; Vander Donckt, M.; Viret, S.; Khvedelidze, A.; Tsamalaidze, Z.; Autermann, C.; Feld, L.; Kiesel, M. K.; Klein, K.; Lipinski, M.; Preuten, M.; Schomakers, C.; Schulz, J.; Verlage, T.; Zhukov, V.; Albert, A.; Dietz-Laursonn, E.; Duchardt, D.; Endres, M.; Erdmann, M.; Erdweg, S.; Esch, T.; Fischer, R.; Güth, A.; Hamer, M.; Hebbeker, T.; Heidemann, C.; Hoepfner, K.; Knutzen, S.; Merschmeyer, M.; Meyer, A.; Millet, P.; Mukherjee, S.; Pook, T.; Radziej, M.; Reithler, H.; Rieger, M.; Scheuch, F.; Teyssier, D.; Thüer, S.; Flügge, G.; Kargoll, B.; Kress, T.; Künsken, A.; Lingemann, J.; Müller, T.; Nehrkorn, A.; Nowack, A.; Pistone, C.; Pooth, O.; Stahl, A.; Aldaya Martin, M.; Arndt, T.; Asawatangtrakuldee, C.; Beernaert, K.; Behnke, O.; Behrens, U.; Bermúdez Martínez, A.; Bin Anuar, A. A.; Borras, K.; Botta, V.; Campbell, A.; Connor, P.; Contreras-Campana, C.; Costanza, F.; Diez Pardos, C.; Eckerlin, G.; Eckstein, D.; Eichhorn, T.; Eren, E.; Gallo, E.; Garay Garcia, J.; Geiser, A.; Gizhko, A.; Grados Luyando, J. M.; Grohsjean, A.; Gunnellini, P.; Guthoff, M.; Harb, A.; Hauk, J.; Hempel, M.; Jung, H.; Kalogeropoulos, A.; Kasemann, M.; Keaveney, J.; Kleinwort, C.; Korol, I.; Krücker, D.; Lange, W.; Lelek, A.; Lenz, T.; Leonard, J.; Lipka, K.; Lohmann, W.; Mankel, R.; Melzer-Pellmann, I.-A.; Meyer, A. B.; Mittag, G.; Mnich, J.; Mussgiller, A.; Ntomari, E.; Pitzl, D.; Raspereza, A.; Roland, B.; Savitskyi, M.; Saxena, P.; Shevchenko, R.; Spannagel, S.; Stefaniuk, N.; Van Onsem, G. P.; Walsh, R.; Wen, Y.; Wichmann, K.; Wissing, C.; Zenaiev, O.; Bein, S.; Blobel, V.; Centis Vignali, M.; Dreyer, T.; Garutti, E.; Gonzalez, D.; Haller, J.; Hinzmann, A.; Hoffmann, M.; Karavdina, A.; Klanner, R.; Kogler, R.; Kovalchuk, N.; Kurz, S.; Lapsien, T.; Marchesini, I.; Marconi, D.; Meyer, M.; Niedziela, M.; Nowatschin, D.; Pantaleo, F.; Peiffer, T.; Perieanu, A.; Scharf, C.; Schleper, P.; Schmidt, A.; Schumann, S.; Schwandt, J.; Sonneveld, J.; Stadie, H.; Steinbrück, G.; Stober, F. M.; Stöver, M.; Tholen, H.; Troendle, D.; Usai, E.; Vanelderen, L.; Vanhoefer, A.; Vormwald, B.; Akbiyik, M.; Barth, C.; Baur, S.; Butz, E.; Caspart, R.; Chwalek, T.; Colombo, F.; De Boer, W.; Dierlamm, A.; Freund, B.; Friese, R.; Giffels, M.; Haitz, D.; Hartmann, F.; Heindl, S. M.; Husemann, U.; Kassel, F.; Kudella, S.; Mildner, H.; Mozer, M. U.; Müller, Th.; Plagge, M.; Quast, G.; Rabbertz, K.; Schröder, M.; Shvetsov, I.; Sieber, G.; Simonis, H. J.; Ulrich, R.; Wayand, S.; Weber, M.; Weiler, T.; Williamson, S.; Wöhrmann, C.; Wolf, R.; Anagnostou, G.; Daskalakis, G.; Geralis, T.; Giakoumopoulou, V. A.; Kyriakis, A.; Loukas, D.; Topsis-Giotis, I.; Karathanasis, G.; Kesisoglou, S.; Panagiotou, A.; Saoulidou, N.; Kousouris, K.; Evangelou, I.; Foudas, C.; Kokkas, P.; Mallios, S.; Manthos, N.; Papadopoulos, I.; Paradas, E.; Strologas, J.; Triantis, F. A.; Csanad, M.; Filipovic, N.; Pasztor, G.; Veres, G. I.; Bencze, G.; Hajdu, C.; Horvath, D.; Hunyadi, Á.; Sikler, F.; Veszpremi, V.; Zsigmond, A. J.; Beni, N.; Czellar, S.; Karancsi, J.; Makovec, A.; Molnar, J.; Szillasi, Z.; Bartók, M.; Raics, P.; Trocsanyi, Z. L.; Ujvari, B.; Choudhury, S.; Komaragiri, J. R.; Bahinipati, S.; Bhowmik, S.; Mal, P.; Mandal, K.; Nayak, A.; Sahoo, D. K.; Sahoo, N.; Swain, S. K.; Bansal, S.; Beri, S. B.; Bhatnagar, V.; Chawla, R.; Dhingra, N.; Kalsi, A. K.; Kaur, A.; Kaur, M.; Kumar, R.; Kumari, P.; Mehta, A.; Singh, J. B.; Walia, G.; Kumar, Ashok; Shah, Aashaq; Bhardwaj, A.; Chauhan, S.; Choudhary, B. C.; Garg, R. B.; Keshri, S.; Kumar, A.; Malhotra, S.; Naimuddin, M.; Ranjan, K.; Sharma, R.; Bhardwaj, R.; Bhattacharya, R.; Bhattacharya, S.; Bhawandeep, U.; Dey, S.; Dutt, S.; Dutta, S.; Ghosh, S.; Majumdar, N.; Modak, A.; Mondal, K.; Mukhopadhyay, S.; Nandan, S.; Purohit, A.; Roy, A.; Roy, D.; Roy Chowdhury, S.; Sarkar, S.; Sharan, M.; Thakur, S.; Behera, P. K.; Chudasama, R.; Dutta, D.; Jha, V.; Kumar, V.; Mohanty, A. K.; Netrakanti, P. K.; Pant, L. M.; Shukla, P.; Topkar, A.; Aziz, T.; Dugad, S.; Mahakud, B.; Mitra, S.; Mohanty, G. B.; Sur, N.; Sutar, B.; Banerjee, S.; Bhattacharya, S.; Chatterjee, S.; Das, P.; Guchait, M.; Jain, Sa.; Kumar, S.; Maity, M.; Majumder, G.; Mazumdar, K.; Sarkar, T.; Wickramage, N.; Chauhan, S.; Dube, S.; Hegde, V.; Kapoor, A.; Kothekar, K.; Pandey, S.; Rane, A.; Sharma, S.; Chenarani, S.; Eskandari Tadavani, E.; Etesami, S. M.; Khakzad, M.; Mohammadi Najafabadi, M.; Naseri, M.; Paktinat Mehdiabadi, S.; Rezaei Hosseinabadi, F.; Safarzadeh, B.; Zeinali, M.; Felcini, M.; Grunewald, M.; Abbrescia, M.; Calabria, C.; Colaleo, A.; Creanza, D.; Cristella, L.; De Filippis, N.; De Palma, M.; Errico, F.; Fiore, L.; Iaselli, G.; Lezki, S.; Maggi, G.; Maggi, M.; Miniello, G.; My, S.; Nuzzo, S.; Pompili, A.; Pugliese, G.; Radogna, R.; Ranieri, A.; Selvaggi, G.; Sharma, A.; Silvestris, L.; Venditti, R.; Verwilligen, P.; Abbiendi, G.; Battilana, C.; Bonacorsi, D.; Braibant-Giacomelli, S.; Campanini, R.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Chhibra, S. S.; Codispoti, G.; Cuffiani, M.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Fasanella, D.; Giacomelli, P.; Grandi, C.; Guiducci, L.; Marcellini, S.; Masetti, G.; Montanari, A.; Navarria, F. L.; Perrotta, A.; Rossi, A. M.; Rovelli, T.; Siroli, G. P.; Tosi, N.; Albergo, S.; Costa, S.; Di Mattia, A.; Giordano, F.; Potenza, R.; Tricomi, A.; Tuve, C.; Barbagli, G.; Chatterjee, K.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Lenzi, P.; Meschini, M.; Paoletti, S.; Russo, L.; Sguazzoni, G.; Strom, D.; Viliani, L.; Benussi, L.; Bianco, S.; Fabbri, F.; Piccolo, D.; Primavera, F.; Calvelli, V.; Ferro, F.; Robutti, E.; Tosi, S.; Benaglia, A.; Brianza, L.; Brivio, F.; Ciriolo, V.; Dinardo, M. E.; Fiorendi, S.; Gennai, S.; Ghezzi, A.; Govoni, P.; Malberti, M.; Malvezzi, S.; Manzoni, R. A.; Menasce, D.; Moroni, L.; Paganoni, M.; Pauwels, K.; Pedrini, D.; Pigazzini, S.; Ragazzi, S.; Redaelli, N.; Tabarelli de Fatis, T.; Buontempo, S.; Cavallo, N.; Di Guida, S.; Fabozzi, F.; Fienga, F.; Iorio, A. O. M.; Khan, W. A.; Lista, L.; Meola, S.; Paolucci, P.; Sciacca, C.; Thyssen, F.; Azzi, P.; Bacchetta, N.; Benato, L.; Bisello, D.; Boletti, A.; Bragagnolo, A.; Carlin, R.; Carvalho Antunes De Oliveira, A.; Checchia, P.; Dall'Osso, M.; De Castro Manzano, P.; Dorigo, T.; Dosselli, U.; Gasparini, F.; Gasparini, U.; Lacaprara, S.; Lujan, P.; Margoni, M.; Meneguzzo, A. T.; Pozzobon, N.; Ronchese, P.; Rossin, R.; Simonetto, F.; Torassa, E.; Ventura, S.; Zanetti, M.; Zotto, P.; Braghieri, A.; Magnani, A.; Montagna, P.; Ratti, S. P.; Re, V.; Ressegotti, M.; Riccardi, C.; Salvini, P.; Vai, I.; Vitulo, P.; Alunni Solestizi, L.; Biasini, M.; Bilei, G. M.; Cecchi, C.; Ciangottini, D.; Fanò, L.; Lariccia, P.; Leonardi, R.; Manoni, E.; Mantovani, G.; Mariani, V.; Menichelli, M.; Rossi, A.; Santocchia, A.; Spiga, D.; Androsov, K.; Azzurri, P.; Bagliesi, G.; Boccali, T.; Borrello, L.; Castaldi, R.; Ciocci, M. A.; Dell'Orso, R.; Fedi, G.; Giannini, L.; Giassi, A.; Grippo, M. T.; Ligabue, F.; Lomtadze, T.; Manca, E.; Mandorli, G.; Martini, L.; Messineo, A.; Palla, F.; Rizzi, A.; Savoy-Navarro, A.; Spagnolo, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Barone, L.; Cavallari, F.; Cipriani, M.; Daci, N.; Del Re, D.; Di Marco, E.; Diemoz, M.; Gelli, S.; Longo, E.; Margaroli, F.; Marzocchi, B.; Meridiani, P.; Organtini, G.; Paramatti, R.; Preiato, F.; Rahatlou, S.; Rovelli, C.; Santanastasio, F.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Bartosik, N.; Bellan, R.; Biino, C.; Cartiglia, N.; Cenna, F.; Costa, M.; Covarelli, R.; Degano, A.; Demaria, N.; Kiani, B.; Mariotti, C.; Maselli, S.; Migliore, E.; Monaco, V.; Monteil, E.; Monteno, M.; Obertino, M. M.; Pacher, L.; Pastrone, N.; Pelliccioni, M.; Pinna Angioni, G. L.; Ravera, F.; Romero, A.; Ruspa, M.; Sacchi, R.; Shchelina, K.; Sola, V.; Solano, A.; Staiano, A.; Traczyk, P.; Belforte, S.; Casarsa, M.; Cossutti, F.; Della Ricca, G.; Zanetti, A.; Kim, D. H.; Kim, G. N.; Kim, M. S.; Lee, J.; Lee, S.; Lee, S. W.; Moon, C. S.; Oh, Y. D.; Sekmen, S.; Son, D. C.; Yang, Y. C.; Lee, A.; Kim, H.; Moon, D. H.; Oh, G.; Brochero Cifuentes, J. A.; Goh, J.; Kim, T. J.; Cho, S.; Choi, S.; Go, Y.; Gyun, D.; Ha, S.; Hong, B.; Jo, Y.; Kim, Y.; Lee, K.; Lee, K. S.; Lee, S.; Lim, J.; Park, S. K.; Roh, Y.; Almond, J.; Kim, J.; Kim, J. S.; Lee, H.; Lee, K.; Nam, K.; Oh, S. B.; Radburn-Smith, B. C.; Seo, S. h.; Yang, U. K.; Yoo, H. D.; Yu, G. B.; Choi, M.; Kim, H.; Kim, J. H.; Lee, J. S. H.; Park, I. C.; Choi, Y.; Hwang, C.; Lee, J.; Yu, I.; Dudenas, V.; Juodagalvis, A.; Vaitkus, J.; Ahmed, I.; Ibrahim, Z. A.; Md Ali, M. A. B.; Mohamad Idris, F.; Wan Abdullah, W. A. T.; Yusli, M. N.; Zolkapli, Z.; Reyes-Almanza, R.; Ramirez-Sanchez, G.; Duran-Osuna, M. C.; Castilla-Valdez, H.; De La Cruz-Burelo, E.; Heredia-De La Cruz, I.; Rabadan-Trejo, R. I.; Lopez-Fernandez, R.; Mejia Guisao, J.; Sanchez-Hernandez, A.; Carrillo Moreno, S.; Oropeza Barrera, C.; Vazquez Valencia, F.; Pedraza, I.; Salazar Ibarguen, H. A.; Uribe Estrada, C.; Morelos Pineda, A.; Krofcheck, D.; Butler, P. H.; Ahmad, A.; Ahmad, M.; Hassan, Q.; Hoorani, H. R.; Saddique, A.; Shah, M. A.; Shoaib, M.; Waqas, M.; Bialkowska, H.; Bluj, M.; Boimska, B.; Frueboes, T.; Górski, M.; Kazana, M.; Nawrocki, K.; Szleper, M.; Zalewski, P.; Bunkowski, K.; Byszuk, A.; Doroba, K.; Kalinowski, A.; Konecki, M.; Krolikowski, J.; Misiura, M.; Olszewski, M.; Pyskir, A.; Walczak, M.; Bargassa, P.; Beirão Da Cruz E Silva, C.; Di Francesco, A.; Faccioli, P.; Galinhas, B.; Gallinaro, M.; Hollar, J.; Leonardo, N.; Lloret Iglesias, L.; Nemallapudi, M. V.; Seixas, J.; Strong, G.; Toldaiev, O.; Vadruccio, D.; Varela, J.; Afanasiev, S.; Bunin, P.; Gavrilenko, M.; Golutvin, I.; Gorbunov, I.; Kamenev, A.; Karjavin, V.; Lanev, A.; Malakhov, A.; Matveev, V.; Palichik, V.; Perelygin, V.; Shmatov, S.; Shulha, S.; Skatchkov, N.; Smirnov, V.; Voytishin, N.; Zarubin, A.; Ivanov, Y.; Kim, V.; Kuznetsova, E.; Levchenko, P.; Murzin, V.; Oreshkin, V.; Smirnov, I.; Sulimov, V.; Uvarov, L.; Vavilov, S.; Vorobyev, A.; Andreev, Yu.; Dermenev, A.; Gninenko, S.; Golubev, N.; Karneyeu, A.; Kirsanov, M.; Krasnikov, N.; Pashenkov, A.; Tlisov, D.; Toropin, A.; Epshteyn, V.; Gavrilov, V.; Lychkovskaya, N.; Popov, V.; Pozdnyakov, I.; Safronov, G.; Spiridonov, A.; Stepennov, A.; Toms, M.; Vlasov, E.; Zhokin, A.; Aushev, T.; Bylinkin, A.; Chadeeva, M.; Parygin, P.; Philippov, D.; Polikarpov, S.; Popova, E.; Rusinov, V.; Andreev, V.; Azarkin, M.; Dremin, I.; Kirakosyan, M.; Terkulov, A.; Baskakov, A.; Belyaev, A.; Boos, E.; Bunichev, V.; Dubinin, M.; Dudko, L.; Ershov, A.; Gribushin, A.; Klyukhin, V.; Kodolova, O.; Lokhtin, I.; Miagkov, I.; Obraztsov, S.; Petrushanko, S.; Savrin, V.; Blinov, V.; Skovpen, Y.; Shtol, D.; Azhgirey, I.; Bayshev, I.; Bitioukov, S.; Elumakhov, D.; Kachanov, V.; Kalinin, A.; Konstantinov, D.; Petrov, V.; Ryutin, R.; Sobol, A.; Troshin, S.; Tyurin, N.; Uzunian, A.; Volkov, A.; Adzic, P.; Cirkovic, P.; Devetak, D.; Dordevic, M.; Milosevic, J.; Rekovic, V.; Alcaraz Maestre, J.; Barrio Luna, M.; Cerrada, M.; Colino, N.; De La Cruz, B.; Delgado Peris, A.; Escalante Del Valle, A.; Fernandez Bedoya, C.; Fernández Ramos, J. P.; Flix, J.; Fouz, M. C.; Garcia-Abia, P.; Gonzalez Lopez, O.; Goy Lopez, S.; Hernandez, J. M.; Josa, M. I.; Moran, D.; Pérez-Calero Yzquierdo, A.; Puerta Pelayo, J.; Quintario Olmeda, A.; Redondo, I.; Romero, L.; Soares, M. S.; Álvarez Fernández, A.; de Trocóniz, J. F.; Missiroli, M.; Cuevas, J.; Erice, C.; Fernandez Menendez, J.; Gonzalez Caballero, I.; González Fernández, J. R.; Palencia Cortezon, E.; Sanchez Cruz, S.; Vischia, P.; Vizan Garcia, J. M.; Cabrillo, I. J.; Calderon, A.; Chazin Quero, B.; Curras, E.; Duarte Campderros, J.; Fernandez, M.; Garcia-Ferrero, J.; Gomez, G.; Lopez Virto, A.; Marco, J.; Martinez Rivero, C.; Martinez Ruiz del Arbol, P.; Matorras, F.; Piedra Gomez, J.; Rodrigo, T.; Ruiz-Jimeno, A.; Scodellaro, L.; Trevisani, N.; Vila, I.; Vilar Cortabitarte, R.; Abbaneo, D.; Auffray, E.; Baillon, P.; Ball, A. H.; Barney, D.; Bianco, M.; Bloch, P.; Bocci, A.; Botta, C.; Camporesi, T.; Castello, R.; Cepeda, M.; Cerminara, G.; Chapon, E.; Chen, Y.; d'Enterria, D.; Dabrowski, A.; Daponte, V.; David, A.; De Gruttola, M.; De Roeck, A.; Dobson, M.; Dorney, B.; du Pree, T.; Dünser, M.; Dupont, N.; Elliott-Peisert, A.; Everaerts, P.; Fallavollita, F.; Franzoni, G.; Fulcher, J.; Funk, W.; Gigi, D.; Gilbert, A.; Gill, K.; Glege, F.; Gulhan, D.; Harris, P.; Hegeman, J.; Innocente, V.; Janot, P.; Karacheban, O.; Kieseler, J.; Kirschenmann, H.; Knünz, V.; Kornmayer, A.; Kortelainen, M. J.; Krammer, M.; Lange, C.; Lecoq, P.; Lourenço, C.; Lucchini, M. T.; Malgeri, L.; Mannelli, M.; Martelli, A.; Meijers, F.; Merlin, J. A.; Mersi, S.; Meschi, E.; Milenovic, P.; Moortgat, F.; Mulders, M.; Neugebauer, H.; Ngadiuba, J.; Orfanelli, S.; Orsini, L.; Pape, L.; Perez, E.; Peruzzi, M.; Petrilli, A.; Petrucciani, G.; Pfeiffer, A.; Pierini, M.; Racz, A.; Reis, T.; Rolandi, G.; Rovere, M.; Sakulin, H.; Schäfer, C.; Schwick, C.; Seidel, M.; Selvaggi, M.; Sharma, A.; Silva, P.; Sphicas, P.; Stakia, A.; Steggemann, J.; Stoye, M.; Tosi, M.; Treille, D.; Triossi, A.; Tsirou, A.; Veckalns, V.; Verweij, M.; Zeuner, W. D.; Bertl, W.; Caminada, L.; Deiters, K.; Erdmann, W.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; Kotlinski, D.; Langenegger, U.; Rohe, T.; Wiederkehr, S. A.; Bäni, L.; Berger, P.; Bianchini, L.; Casal, B.; Dissertori, G.; Dittmar, M.; Donegà, M.; Grab, C.; Heidegger, C.; Hits, D.; Hoss, J.; Kasieczka, G.; Klijnsma, T.; Lustermann, W.; Mangano, B.; Marionneau, M.; Meinhard, M. T.; Meister, D.; Micheli, F.; Musella, P.; Nessi-Tedaldi, F.; Pandolfi, F.; Pata, J.; Pauss, F.; Perrin, G.; Perrozzi, L.; Quittnat, M.; Reichmann, M.; Schönenberger, M.; Shchutska, L.; Tavolaro, V. R.; Theofilatos, K.; Vesterbacka Olsson, M. L.; Wallny, R.; Zhu, D. H.; Aarrestad, T. K.; Amsler, C.; Canelli, M. F.; De Cosa, A.; Del Burgo, R.; Donato, S.; Galloni, C.; Hreus, T.; Kilminster, B.; Pinna, D.; Rauco, G.; Robmann, P.; Salerno, D.; Seitz, C.; Takahashi, Y.; Zucchetta, A.; Candelise, V.; Doan, T. H.; Jain, Sh.; Khurana, R.; Kuo, C. M.; Lin, W.; Pozdnyakov, A.; Yu, S. S.; Kumar, Arun; Chang, P.; Chao, Y.; Chen, K. F.; Chen, P. H.; Fiori, F.; Hsiung, Y.; Liu, Y. F.; Lu, R.-S.; Paganis, E.; Psallidas, A.; Steen, A.; Tsai, J. f.; Asavapibhop, B.; Kovitanggoon, K.; Singh, G.; Srimanobhas, N.; Boran, F.; Cerci, S.; Damarseckin, S.; Demiroglu, Z. S.; Dozen, C.; Dumanoglu, I.; Girgis, S.; Gokbulut, G.; Guler, Y.; Hos, I.; Kangal, E. E.; Kara, O.; Kayis Topaksu, A.; Kiminsu, U.; Oglakci, M.; Onengut, G.; Ozdemir, K.; Sunar Cerci, D.; Tali, B.; Turkcapar, S.; Zorbakir, I. S.; Zorbilmez, C.; Bilin, B.; Karapinar, G.; Ocalan, K.; Yalvac, M.; Zeyrek, M.; Gülmez, E.; Kaya, M.; Kaya, O.; Tekten, S.; Yetkin, E. A.; Agaras, M. N.; Atay, S.; Cakir, A.; Cankocak, K.; Grynyov, B.; Levchuk, L.; Aggleton, R.; Ball, F.; Beck, L.; Brooke, J. J.; Burns, D.; Clement, E.; Cussans, D.; Davignon, O.; Flacher, H.; Goldstein, J.; Grimes, M.; Heath, G. P.; Heath, H. F.; Jacob, J.; Kreczko, L.; Lucas, C.; Newbold, D. M.; Paramesvaran, S.; Poll, A.; Sakuma, T.; Seif El Nasr-storey, S.; Smith, D.; Smith, V. J.; Bell, K. W.; Belyaev, A.; Brew, C.; Brown, R. M.; Calligaris, L.; Cieri, D.; Cockerill, D. J. A.; Coughlan, J. A.; Harder, K.; Harper, S.; Olaiya, E.; Petyt, D.; Shepherd-Themistocleous, C. H.; Thea, A.; Tomalin, I. R.; Williams, T.; Auzinger, G.; Bainbridge, R.; Borg, J.; Breeze, S.; Buchmuller, O.; Bundock, A.; Casasso, S.; Citron, M.; Colling, D.; Corpe, L.; Dauncey, P.; Davies, G.; De Wit, A.; Della Negra, M.; Di Maria, R.; Elwood, A.; Haddad, Y.; Hall, G.; Iles, G.; James, T.; Lane, R.; Laner, C.; Lyons, L.; Magnan, A.-M.; Malik, S.; Mastrolorenzo, L.; Matsushita, T.; Nash, J.; Nikitenko, A.; Palladino, V.; Pesaresi, M.; Raymond, D. M.; Richards, A.; Rose, A.; Scott, E.; Seez, C.; Shtipliyski, A.; Summers, S.; Tapper, A.; Uchida, K.; Vazquez Acosta, M.; Virdee, T.; Wardle, N.; Winterbottom, D.; Wright, J.; Zenz, S. C.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Reid, I. D.; Symonds, P.; Teodorescu, L.; Turner, M.; Borzou, A.; Call, K.; Dittmann, J.; Hatakeyama, K.; Liu, H.; Pastika, N.; Smith, C.; Bartek, R.; Dominguez, A.; Buccilli, A.; Cooper, S. I.; Henderson, C.; Rumerio, P.; West, C.; Arcaro, D.; Avetisyan, A.; Bose, T.; Gastler, D.; Rankin, D.; Richardson, C.; Rohlf, J.; Sulak, L.; Zou, D.; Benelli, G.; Cutts, D.; Garabedian, A.; Hakala, J.; Heintz, U.; Hogan, J. M.; Kwok, K. H. M.; Laird, E.; Landsberg, G.; Mao, Z.; Narain, M.; Pazzini, J.; Piperov, S.; Sagir, S.; Syarif, R.; Yu, D.; Band, R.; Brainerd, C.; Burns, D.; Calderon De La Barca Sanchez, M.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Erbacher, R.; Flores, C.; Funk, G.; Gardner, M.; Ko, W.; Lander, R.; Mclean, C.; Mulhearn, M.; Pellett, D.; Pilot, J.; Shalhout, S.; Shi, M.; Smith, J.; Stolp, D.; Tos, K.; Tripathi, M.; Wang, Z.; Bachtis, M.; Bravo, C.; Cousins, R.; Dasgupta, A.; Florent, A.; Hauser, J.; Ignatenko, M.; Mccoll, N.; Regnard, S.; Saltzberg, D.; Schnaible, C.; Valuev, V.; Bouvier, E.; Burt, K.; Clare, R.; Ellison, J.; Gary, J. W.; Ghiasi Shirazi, S. M. A.; Hanson, G.; Heilman, J.; Jandir, P.; Kennedy, E.; Lacroix, F.; Long, O. R.; Olmedo Negrete, M.; Paneva, M. I.; Shrinivas, A.; Si, W.; Wang, L.; Wei, H.; Wimpenny, S.; Yates, B. R.; Branson, J. G.; Cittolin, S.; Derdzinski, M.; Gerosa, R.; Hashemi, B.; Holzner, A.; Klein, D.; Kole, G.; Krutelyov, V.; Letts, J.; Macneill, I.; Masciovecchio, M.; Olivito, D.; Padhi, S.; Pieri, M.; Sani, M.; Sharma, V.; Simon, S.; Tadel, M.; Vartak, A.; Wasserbaech, S.; Wood, J.; Würthwein, F.; Yagil, A.; Zevi Della Porta, G.; Amin, N.; Bhandari, R.; Bradmiller-Feld, J.; Campagnari, C.; Dishaw, A.; Dutta, V.; Franco Sevilla, M.; George, C.; Golf, F.; Gouskos, L.; Gran, J.; Heller, R.; Incandela, J.; Mullin, S. D.; Ovcharova, A.; Qu, H.; Richman, J.; Stuart, D.; Suarez, I.; Yoo, J.; Anderson, D.; Bendavid, J.; Bornheim, A.; Lawhorn, J. M.; Newman, H. B.; Nguyen, T.; Pena, C.; Spiropulu, M.; Vlimant, J. R.; Xie, S.; Zhang, Z.; Zhu, R. Y.; Andrews, M. B.; Ferguson, T.; Mudholkar, T.; Paulini, M.; Russ, J.; Sun, M.; Vogel, H.; Vorobiev, I.; Weinberg, M.; Cumalat, J. P.; Ford, W. T.; Jensen, F.; Johnson, A.; Krohn, M.; Leontsinis, S.; Mulholland, T.; Stenson, K.; Wagner, S. R.; Alexander, J.; Chaves, J.; Chu, J.; Dittmer, S.; Mcdermott, K.; Mirman, N.; Patterson, J. R.; Rinkevicius, A.; Ryd, A.; Skinnari, L.; Soffi, L.; Tan, S. M.; Tao, Z.; Thom, J.; Tucker, J.; Wittich, P.; Zientek, M.; Abdullin, S.; Albrow, M.; Alyari, M.; Apollinari, G.; Apresyan, A.; Apyan, A.; Banerjee, S.; Bauerdick, L. A. T.; Beretvas, A.; Berryhill, J.; Bhat, P. C.; Bolla, G.; Burkett, K.; Butler, J. N.; Canepa, A.; Cerati, G. B.; Cheung, H. W. K.; Chlebana, F.; Cremonesi, M.; Duarte, J.; Elvira, V. D.; Freeman, J.; Gecse, Z.; Gottschalk, E.; Gray, L.; Green, D.; Grünendahl, S.; Gutsche, O.; Harris, R. M.; Hasegawa, S.; Hirschauer, J.; Hu, Z.; Jayatilaka, B.; Jindariani, S.; Johnson, M.; Joshi, U.; Klima, B.; Kreis, B.; Lammel, S.; Lincoln, D.; Lipton, R.; Liu, M.; Liu, T.; Lopes De Sá, R.; Lykken, J.; Maeshima, K.; Magini, N.; Marraffino, J. M.; Maruyama, S.; Mason, D.; McBride, P.; Merkel, P.; Mrenna, S.; Nahn, S.; O'Dell, V.; Pedro, K.; Prokofyev, O.; Rakness, G.; Ristori, L.; Schneider, B.; Sexton-Kennedy, E.; Soha, A.; Spalding, W. J.; Spiegel, L.; Stoynev, S.; Strait, J.; Strobbe, N.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Vernieri, C.; Verzocchi, M.; Vidal, R.; Wang, M.; Weber, H. A.; Whitbeck, A.; Acosta, D.; Avery, P.; Bortignon, P.; Bourilkov, D.; Brinkerhoff, A.; Carnes, A.; Carver, M.; Curry, D.; Field, R. D.; Furic, I. K.; Konigsberg, J.; Korytov, A.; Kotov, K.; Ma, P.; Matchev, K.; Mei, H.; Mitselmakher, G.; Rank, D.; Sperka, D.; Terentyev, N.; Thomas, L.; Wang, J.; Wang, S.; Yelton, J.; Joshi, Y. R.; Linn, S.; Markowitz, P.; Rodriguez, J. L.; Ackert, A.; Adams, T.; Askew, A.; Hagopian, S.; Hagopian, V.; Johnson, K. F.; Kolberg, T.; Martinez, G.; Perry, T.; Prosper, H.; Saha, A.; Santra, A.; Sharma, V.; Yohay, R.; Baarmand, M. M.; Bhopatkar, V.; Colafranceschi, S.; Hohlmann, M.; Noonan, D.; Roy, T.; Yumiceva, F.; Adams, M. R.; Apanasevich, L.; Berry, D.; Betts, R. R.; Cavanaugh, R.; Chen, X.; Evdokimov, O.; Gerber, C. E.; Hangal, D. A.; Hofman, D. J.; Jung, K.; Kamin, J.; Sandoval Gonzalez, I. D.; Tonjes, M. B.; Trauger, H.; Varelas, N.; Wang, H.; Wu, Z.; Zhang, J.; Bilki, B.; Clarida, W.; Dilsiz, K.; Durgut, S.; Gandrajula, R. P.; Haytmyradov, M.; Khristenko, V.; Merlo, J.-P.; Mermerkaya, H.; Mestvirishvili, A.; Moeller, A.; Nachtman, J.; Ogul, H.; Onel, Y.; Ozok, F.; Penzo, A.; Snyder, C.; Tiras, E.; Wetzel, J.; Yi, K.; Blumenfeld, B.; Cocoros, A.; Eminizer, N.; Fehling, D.; Feng, L.; Gritsan, A. V.; Maksimovic, P.; Roskes, J.; Sarica, U.; Swartz, M.; Xiao, M.; You, C.; Al-bataineh, A.; Baringer, P.; Bean, A.; Boren, S.; Bowen, J.; Castle, J.; Khalil, S.; Kropivnitskaya, A.; Majumder, D.; Mcbrayer, W.; Murray, M.; Royon, C.; Sanders, S.; Schmitz, E.; Tapia Takaki, J. D.; Wang, Q.; Ivanov, A.; Kaadze, K.; Maravin, Y.; Mohammadi, A.; Saini, L. K.; Skhirtladze, N.; Toda, S.; Rebassoo, F.; Wright, D.; Anelli, C.; Baden, A.; Baron, O.; Belloni, A.; Calvert, B.; Eno, S. C.; Ferraioli, C.; Hadley, N. J.; Jabeen, S.; Jeng, G. Y.; Kellogg, R. G.; Kunkle, J.; Mignerey, A. C.; Ricci-Tam, F.; Shin, Y. H.; Skuja, A.; Tonwar, S. C.; Abercrombie, D.; Allen, B.; Azzolini, V.; Barbieri, R.; Baty, A.; Bi, R.; Brandt, S.; Busza, W.; Cali, I. A.; D'Alfonso, M.; Demiragli, Z.; Gomez Ceballos, G.; Goncharov, M.; Hsu, D.; Iiyama, Y.; Innocenti, G. M.; Klute, M.; Kovalskyi, D.; Lai, Y. S.; Lee, Y.-J.; Levin, A.; Luckey, P. D.; Maier, B.; Marini, A. C.; Mcginn, C.; Mironov, C.; Narayanan, S.; Niu, X.; Paus, C.; Roland, C.; Roland, G.; Salfeld-Nebgen, J.; Stephans, G. S. F.; Tatar, K.; Velicanu, D.; Wang, J.; Wang, T. W.; Wyslouch, B.; Benvenuti, A. C.; Chatterjee, R. M.; Evans, A.; Hansen, P.; Kalafut, S.; Kubota, Y.; Lesko, Z.; Mans, J.; Nourbakhsh, S.; Ruckstuhl, N.; Rusack, R.; Turkewitz, J.; Acosta, J. G.; Oliveros, S.; Avdeeva, E.; Bloom, K.; Claes, D. R.; Fangmeier, C.; Gonzalez Suarez, R.; Kamalieddin, R.; Kravchenko, I.; Monroy, J.; Siado, J. E.; Snow, G. R.; Stieger, B.; Dolen, J.; Godshalk, A.; Harrington, C.; Iashvili, I.; Nguyen, D.; Parker, A.; Rappoccio, S.; Roozbahani, B.; Alverson, G.; Barberis, E.; Hortiangtham, A.; Massironi, A.; Morse, D. M.; Nash, D.; Orimoto, T.; Teixeira De Lima, R.; Trocino, D.; Wood, D.; Bhattacharya, S.; Charaf, O.; Hahn, K. A.; Mucia, N.; Odell, N.; Pollack, B.; Schmitt, M. H.; Sung, K.; Trovato, M.; Velasco, M.; Dev, N.; Hildreth, M.; Hurtado Anampa, K.; Jessop, C.; Karmgard, D. J.; Kellams, N.; Lannon, K.; Loukas, N.; Marinelli, N.; Meng, F.; Mueller, C.; Musienko, Y.; Planer, M.; Reinsvold, A.; Ruchti, R.; Smith, G.; Taroni, S.; Wayne, M.; Wolf, M.; Woodard, A.; Alimena, J.; Antonelli, L.; Bylsma, B.; Durkin, L. S.; Flowers, S.; Francis, B.; Hart, A.; Hill, C.; Ji, W.; Liu, B.; Luo, W.; Puigh, D.; Winer, B. L.; Wulsin, H. W.; Cooperstein, S.; Driga, O.; Elmer, P.; Hardenbrook, J.; Hebda, P.; Higginbotham, S.; Lange, D.; Luo, J.; Marlow, D.; Mei, K.; Ojalvo, I.; Olsen, J.; Palmer, C.; Piroué, P.; Stickland, D.; Tully, C.; Malik, S.; Norberg, S.; Barker, A.; Barnes, V. E.; Das, S.; Folgueras, S.; Gutay, L.; Jha, M. K.; Jones, M.; Jung, A. W.; Khatiwada, A.; Miller, D. H.; Neumeister, N.; Peng, C. C.; Schulte, J. F.; Sun, J.; Wang, F.; Xie, W.; Cheng, T.; Parashar, N.; Stupak, J.; Adair, A.; Akgun, B.; Chen, Z.; Ecklund, K. M.; Geurts, F. J. M.; Guilbaud, M.; Li, W.; Michlin, B.; Northup, M.; Padley, B. P.; Roberts, J.; Rorie, J.; Tu, Z.; Zabel, J.; Bodek, A.; de Barbaro, P.; Demina, R.; Duh, Y. t.; Ferbel, T.; Galanti, M.; Garcia-Bellido, A.; Han, J.; Hindrichs, O.; Khukhunaishvili, A.; Lo, K. H.; Tan, P.; Verzetti, M.; Ciesielski, R.; Goulianos, K.; Mesropian, C.; Agapitos, A.; Chou, J. P.; Gershtein, Y.; Gómez Espinosa, T. A.; Halkiadakis, E.; Heindl, M.; Hughes, E.; Kaplan, S.; Kunnawalkam Elayavalli, R.; Kyriacou, S.; Lath, A.; Montalvo, R.; Nash, K.; Osherson, M.; Saka, H.; Salur, S.; Schnetzer, S.; Sheffield, D.; Somalwar, S.; Stone, R.; Thomas, S.; Thomassen, P.; Walker, M.; Delannoy, A. G.; Foerster, M.; Heideman, J.; Riley, G.; Rose, K.; Spanier, S.; Thapa, K.; Bouhali, O.; Castaneda Hernandez, A.; Celik, A.; Dalchenko, M.; De Mattia, M.; Delgado, A.; Dildick, S.; Eusebi, R.; Gilmore, J.; Huang, T.; Kamon, T.; Mueller, R.; Pakhotin, Y.; Patel, R.; Perloff, A.; Perniè, L.; Rathjens, D.; Safonov, A.; Tatarinov, A.; Ulmer, K. A.; Akchurin, N.; Damgov, J.; De Guio, F.; Dudero, P. R.; Faulkner, J.; Gurpinar, E.; Kunori, S.; Lamichhane, K.; Lee, S. W.; Libeiro, T.; Peltola, T.; Undleeb, S.; Volobouev, I.; Wang, Z.; Greene, S.; Gurrola, A.; Janjam, R.; Johns, W.; Maguire, C.; Melo, A.; Ni, H.; Padeken, K.; Sheldon, P.; Tuo, S.; Velkovska, J.; Xu, Q.; Arenton, M. W.; Barria, P.; Cox, B.; Hirosky, R.; Joyce, M.; Ledovskoy, A.; Li, H.; Neu, C.; Sinthuprasith, T.; Wang, Y.; Wolfe, E.; Xia, F.; Harr, R.; Karchin, P. E.; Sturdy, J.; Zaleski, S.; Brodski, M.; Buchanan, J.; Caillol, C.; Dasu, S.; Dodd, L.; Duric, S.; Gomber, B.; Grothe, M.; Herndon, M.; Hervé, A.; Hussain, U.; Klabbers, P.; Lanaro, A.; Levine, A.; Long, K.; Loveless, R.; Pierro, G. A.; Polese, G.; Ruggles, T.; Savin, A.; Smith, N.; Smith, W. H.; Taylor, D.; Woods, N.; CMS Collaboration

    2018-04-01

    A measurement of the H → ττ signal strength is performed using events recorded in proton-proton collisions by the CMS experiment at the LHC in 2016 at a center-of-mass energy of 13TeV. The data set corresponds to an integrated luminosity of 35.9fb-1. The H → ττ signal is established with a significance of 4.9 standard deviations, to be compared to an expected significance of 4.7 standard deviations. The best fit of the product of the observed H → ττ signal production cross section and branching fraction is 1.09-0.26+0.27 times the standard model expectation. The combination with the corresponding measurement performed with data collected by the CMS experiment at center-of-mass energies of 7 and 8TeV leads to an observed significance of 5.9 standard deviations, equal to the expected significance. This is the first observation of Higgs boson decays to τ leptons by a single experiment.

  14. Passive PE Sampling in Support of In Situ Remediation of Contaminated Sediments

    DTIC Science & Technology

    2015-08-01

    control RPD relative percent difference RSD relative standard deviation SERDP Strategic Environmental Research and Development Program SOPs...sediments from 2 stations, each at 4 PCB spike levels, for four individual congeners was 22 ± 6 % relative standard deviation ( RSD ). Also, comparison of... RSD (Table 3). However, larger congeners (e.g., congeners #153 and 180) whose approach to equilibrium is less certain, based on small fractions of

  15. Thermal management optimization of an air-cooled Li-ion battery module using pin-fin heat sinks for hybrid electric vehicles

    NASA Astrophysics Data System (ADS)

    Mohammadian, Shahabeddin K.; Zhang, Yuwen

    2015-01-01

    Three dimensional transient thermal analysis of an air-cooled module that contains prismatic Li-ion cells next to a special kind of aluminum pin fin heat sink whose heights of pin fins increase linearly through the width of the channel in air flow direction was studied for thermal management of Lithium-ion battery pack. The effects of pin fins arrangements, discharge rates, inlet air flow velocities, and inlet air temperatures on the battery were investigated. The results showed that despite of heat sinks with uniform pin fin heights that increase the standard deviation of the temperature field, using this kind of pin fin heat sink compare to the heat sink without pin fins not only decreases the bulk temperature inside the battery, but also decreases the standard deviation of the temperature field inside the battery as well. Increasing the inlet air temperature leads to decreasing the standard deviation of the temperature field while increases the maximum temperature of the battery. Furthermore, increasing the inlet air velocity first increases the standard deviation of the temperature field till reaches to the maximum point, and after that decreases. Also, increasing the inlet air velocity leads to decrease in the maximum temperature of the battery.

  16. TU-G-204-05: The Effects of CT Acquisition and Reconstruction Conditions On Computed Texture Feature Values of Lung Lesions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lo, P; Young, S; Kim, G

    2015-06-15

    Purpose: Texture features have been investigated as a biomarker of response and malignancy. Because these features reflect local differences in density, they may be influenced by acquisition and reconstruction parameters. The purpose of this study was to investigate the effects of radiation dose level and reconstruction method on features derived from lung lesions. Methods: With IRB approval, 33 lung tumor cases were identified from clinically indicated thoracic CT scans in which the raw projection (sinogram) data were available. Based on a previously-published technique, noise was added to the raw data to simulate reduced-dose versions of each case at 25%, 10%more » and 3% of the original dose. Original and simulated reduced dose projection data were reconstructed with conventional and two iterative-reconstruction settings, yielding 12 combinations of dose/recon conditions. One lesion from each case was contoured. At the reference condition (full dose, conventional recon), 17 lesions were randomly selected for repeat contouring (repeatability). For each lesion at each dose/recon condition, 151 texture measures were calculated. A paired differences approach was employed to compare feature variation from repeat contours at the reference condition to the variation observed in other dose/recon conditions (reproducibility). The ratio of standard deviation of the reproducibility to repeatability was used as the variation measure for each feature. Results: The mean variation (standard deviation) across dose levels and kernel was significantly different with a ratio of 2.24 (±5.85) across texture features (p=0.01). The mean variation (standard deviation) across dose levels with conventional recon was also significantly different with 2.30 (7.11) (p=0.025). The mean variation across reconstruction settings of original dose has a trend in showing difference with 1.35 (2.60) among all features (p=0.09). Conclusion: Texture features varied considerably with variations in dose and reconstruction condition. Care should be taken to standardize these conditions when using texture as a quantitative feature. This effort supported in part by a grant from the National Cancer Institute’s Quantitative Imaging Network (QIN): U01 CA181156; The UCLA Department of Radiology has a Master Research Agreement with Siemens Healthcare; Dr. McNitt-Gray has previously received research support from Siemens Healthcare.« less

  17. SU-G-IeP3-11: On the Utility of Pixel Variance to Characterize Noise for Image Receptors of Digital Radiography Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Finley, C; Dave, J

    Purpose: To characterize noise for image receptors of digital radiography systems based on pixel variance. Methods: Nine calibrated digital image receptors associated with nine new portable digital radiography systems (Carestream Health, Inc., Rochester, NY) were used in this study. For each image receptor, thirteen images were acquired with RQA5 beam conditions for input detector air kerma ranging from 0 to 110 µGy, and linearized ‘For Processing’ images were extracted. Mean pixel value (MPV), standard deviation (SD) and relative noise (SD/MPV) were obtained from each image using ROI sizes varying from 2.5×2.5 to 20×20 mm{sup 2}. Variance (SD{sup 2}) was plottedmore » as a function of input detector air kerma and the coefficients of the quadratic fit were used to derive structured, quantum and electronic noise coefficients. Relative noise was also fitted as a function of input detector air kerma to identify noise sources. The fitting functions used least-squares approach. Results: The coefficient of variation values obtained using different ROI sizes was less than 1% for all the images. The structured, quantum and electronic coefficients obtained from the quadratic fit of variance (r>0.97) were 0.43±0.10, 3.95±0.27 and 2.89±0.74 (mean ± standard deviation), respectively, indicating that overall the quantum noise was the dominant noise source. However, for one system electronic noise coefficient (3.91) was greater than quantum noise coefficient (3.56) indicating electronic noise to be dominant. Using relative noise values, the power parameter of the fitting equation (|r|>0.93) showed a mean and standard deviation of 0.46±0.02. A 0.50 value for this power parameter indicates quantum noise to be the dominant noise source whereas values around 0.50 indicate presence of other noise sources. Conclusion: Characterizing noise from pixel variance assists in identifying contributions from various noise sources that, eventually, may affect image quality. This approach may be integrated during periodic quality assessments of digital image receptors.« less

  18. Quantitative Evaluation for Differentiating Malignant and Benign Thyroid Nodules Using Histogram Analysis of Grayscale Sonograms.

    PubMed

    Nam, Se Jin; Yoo, Jaeheung; Lee, Hye Sun; Kim, Eun-Kyung; Moon, Hee Jung; Yoon, Jung Hyun; Kwak, Jin Young

    2016-04-01

    To evaluate the diagnostic value of histogram analysis using grayscale sonograms for differentiation of malignant and benign thyroid nodules. From July 2013 through October 2013, 579 nodules in 563 patients who had undergone ultrasound-guided fine-needle aspiration were included. For the grayscale histogram analysis, pixel echogenicity values in regions of interest were measured as 0 to 255 (0, black; 255, white) with in-house software. Five parameters (mean, skewness, kurtosis, standard deviation, and entropy) were obtained for each thyroid nodule. With principal component analysis, an index was derived. Diagnostic performance rates for the 5 histogram parameters and the principal component analysis index were calculated. A total of 563 patients were included in the study (mean age ± SD, 50.3 ± 12.3 years;range, 15-79 years). Of the 579 nodules, 431 were benign, and 148 were malignant. Among the 5 parameters and the principal component analysis index, the standard deviation (75.546 ± 14.153 versus 62.761 ± 16.01; P < .001), kurtosis (3.898 ± 2.652 versus 6.251 ± 9.102; P < .001), entropy (0.16 ± 0.135 versus 0.239 ± 0.185; P < .001), and principal component analysis index (-0.386±0.774 versus 0.134 ± 0.889; P < .001) were significantly different between the malignant and benign nodules. With the calculated cutoff values, the areas under the curve were 0.681 (95% confidence interval, 0.643-0.721) for standard deviation, 0.661 (0.620-0.703) for principal component analysis index, 0.651 (0.607-0.691) for kurtosis, 0.638 (0.596-0.681) for entropy, and 0.606 (0.563-0.647) for skewness. The subjective analysis of grayscale sonograms by radiologists alone showed an area under the curve of 0.861 (0.833-0.888). Grayscale histogram analysis was feasible for differentiating malignant and benign thyroid nodules but did not show better diagnostic performance than subjective analysis performed by radiologists. Further technical advances will be needed to objectify interpretations of thyroid grayscale sonograms. © 2016 by the American Institute of Ultrasound in Medicine.

  19. Quality assurance for the clinical implementation of kilovoltage intrafraction monitoring for prostate cancer VMAT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ng, J. A.; Booth, J. T.; O’Brien, R. T.

    2014-11-01

    Purpose: Kilovoltage intrafraction monitoring (KIM) is a real-time 3D tumor monitoring system for cancer radiotherapy. KIM uses the commonly available gantry-mounted x-ray imager as input, making this method potentially more widely available than dedicated real-time 3D tumor monitoring systems. KIM is being piloted in a clinical trial for prostate cancer patients treated with VMAT (NCT01742403). The purpose of this work was to develop clinical process and quality assurance (QA) practices for the clinical implementation of KIM. Methods: Informed by and adapting existing guideline documents from other real-time monitoring systems, KIM-specific QA practices were developed. The following five KIM-specific QA testsmore » were included: (1) static localization accuracy, (2) dynamic localization accuracy, (3) treatment interruption accuracy, (4) latency measurement, and (5) clinical conditions accuracy. Tests (1)–(4) were performed using KIM to measure static and representative patient-derived prostate motion trajectories using a 3D programmable motion stage supporting an anthropomorphic phantom with implanted gold markers to represent the clinical treatment scenario. The threshold for system tolerable latency is <1 s. The tolerances for all other tests are that both the mean and standard deviation of the difference between the programmed trajectory and the measured data are <1 mm. The (5) clinical conditions accuracy test compared the KIM measured positions with those measured by kV/megavoltage (MV) triangulation from five treatment fractions acquired in a previous pilot study. Results: For the (1) static localization, (2) dynamic localization, and (3) treatment interruption accuracy tests, the mean and standard deviation of the difference are <1.0 mm. (4) The measured latency is 350 ms. (5) For the tests with previously acquired patient data, the mean and standard deviation of the difference between KIM and kV/MV triangulation are <1.0 mm. Conclusions: Clinical process and QA practices for the safe clinical implementation of KIM, a novel real-time monitoring system using commonly available equipment, have been developed and implemented for prostate cancer VMAT.« less

  20. Spatial and temporal variability of the Aridity Index in Greece

    NASA Astrophysics Data System (ADS)

    Nastos, Panagiotis T.; Politi, Nadia; Kapsomenakis, John

    2013-01-01

    The objective of this paper is to study the spatial and temporal variability of the Aridity Index (AI) in Greece, per decade, during the 50-year period (1951-2000). Besides, the projected changes in ensemble mean AI between the period 1961-1990 (reference period) and the periods 2021-2050 (near future) and 2071-2100 (far future) along with the inter-model standard deviations were presented, based on the simulation results, derived from a number of Regional Climatic Models (RCMs), within the ENSEMBLE European Project. The projection of the future climate was done under SRES A1B. The climatic data used, concern monthly precipitation totals and air temperature from 28 meteorological stations (22 stations from the Hellenic National Meteorological Service and 6 stations from neighboring countries, taken from the Monthly Climatic Data for the World). The estimation of the AI was carried out based on the potential evapotranspiration (PET) defined by Thornthwaite (1948). The data processing was done by the application of the statistical package R-project and the Geographical Information Systems (GIS). The results of the analysis showed that, within the examined period (1951-2000), a progressive shift from the "humid" class, which characterized the wider area of Greece, towards the "sub-humid" and "semi-arid" classes appeared in the eastern Crete Island, the Cyclades complex, the Evia and Attica, that is mainly the eastern Greece. The most significant change appears during the period 1991-2000. The future projections at the end of twentieth century, using ensemble mean simulations from 8 RCMs, show that drier conditions are expected to establish in regions of Greece (Attica, eastern continental Greece, Cyclades, Dodecanese, eastern Crete Island and northern Aegean). The inter-model standard deviation over these regions ranges from 0.02 to 0.05 against high values (0.09-0.15) illustrated in western mountainous continental Greece, during 2021-2050. Higher values of inter-model standard deviation appear in the 2071-2100 ranging from 0.02 to 0.10 reaching even 0.50 over mountainous regions of the country.

  1. Assessment of MODIS-derived indices (2001-2013) to drought across Taiwan's forests

    NASA Astrophysics Data System (ADS)

    Chang, Chung-Te; Wang, Hsueh-Ching; Huang, Cho-ying

    2018-05-01

    Tropical and subtropical ecosystems, the largest terrestrial carbon pools, are very susceptible to the variability of seasonal precipitation. However, the assessment of drought conditions in these regions is often overlooked due to the preconceived notion of the presence of high humidity. Drought indices derived from remotely sensed imagery have been commonly used for large-scale monitoring, but feasibility of drought assessment may vary across regions due to climate regimes and local biophysical conditions. Therefore, this study aims to evaluate the feasibility of 11 commonly used MODIS-derived vegetation/drought index in the forest regions of Taiwan through comparison with the station-based standardized precipitation index with a 3-month time scale (SPI3). The drought indices were further transformed (standardized anomaly, SA) to make them better delineate the spatiotemporal variations of drought conditions. The results showed that the Normalized Difference Infrared Index utilizing the near-infrared and shortwave infrared bands (NDII6) may be more superior to other indices in delineating drought patterns. Overall, the NDII6 SA-SPI3 pair yielded the highest correlation (mean r ± standard deviation = 0.31 ± 0.13) and was most significant in central and south Taiwan ( r = 0.50-0.90) during the cold, dry season (January and April). This study illustrated that the NDII6 is suitable to delineate drought conditions in a relatively humid region. The results suggested the better performance of the NDII6 SA-SPI3 across the high climate gradient, especially in the regions with dramatic interannual amplifications of rainfall. This synthesis was conducted across a wide bioclimatic gradient, and the findings could be further generalized to a much broader geographical extent.

  2. Assessment of MODIS-derived indices (2001-2013) to drought across Taiwan's forests

    NASA Astrophysics Data System (ADS)

    Chang, Chung-Te; Wang, Hsueh-Ching; Huang, Cho-ying

    2017-12-01

    Tropical and subtropical ecosystems, the largest terrestrial carbon pools, are very susceptible to the variability of seasonal precipitation. However, the assessment of drought conditions in these regions is often overlooked due to the preconceived notion of the presence of high humidity. Drought indices derived from remotely sensed imagery have been commonly used for large-scale monitoring, but feasibility of drought assessment may vary across regions due to climate regimes and local biophysical conditions. Therefore, this study aims to evaluate the feasibility of 11 commonly used MODIS-derived vegetation/drought index in the forest regions of Taiwan through comparison with the station-based standardized precipitation index with a 3-month time scale (SPI3). The drought indices were further transformed (standardized anomaly, SA) to make them better delineate the spatiotemporal variations of drought conditions. The results showed that the Normalized Difference Infrared Index utilizing the near-infrared and shortwave infrared bands (NDII6) may be more superior to other indices in delineating drought patterns. Overall, the NDII6 SA-SPI3 pair yielded the highest correlation (mean r ± standard deviation = 0.31 ± 0.13) and was most significant in central and south Taiwan (r = 0.50-0.90) during the cold, dry season (January and April). This study illustrated that the NDII6 is suitable to delineate drought conditions in a relatively humid region. The results suggested the better performance of the NDII6 SA-SPI3 across the high climate gradient, especially in the regions with dramatic interannual amplifications of rainfall. This synthesis was conducted across a wide bioclimatic gradient, and the findings could be further generalized to a much broader geographical extent.

  3. The linear sizes tolerances and fits system modernization

    NASA Astrophysics Data System (ADS)

    Glukhov, V. I.; Grinevich, V. A.; Shalay, V. V.

    2018-04-01

    The study is carried out on the urgent topic for technical products quality providing in the tolerancing process of the component parts. The aim of the paper is to develop alternatives for improving the system linear sizes tolerances and dimensional fits in the international standard ISO 286-1. The tasks of the work are, firstly, to classify as linear sizes the elements additionally linear coordinating sizes that determine the detail elements location and, secondly, to justify the basic deviation of the tolerance interval for the element's linear size. The geometrical modeling method of real details elements, the analytical and experimental methods are used in the research. It is shown that the linear coordinates are the dimensional basis of the elements linear sizes. To standardize the accuracy of linear coordinating sizes in all accuracy classes, it is sufficient to select in the standardized tolerance system only one tolerance interval with symmetrical deviations: Js for internal dimensional elements (holes) and js for external elements (shafts). The main deviation of this coordinating tolerance is the average zero deviation, which coincides with the nominal value of the coordinating size. Other intervals of the tolerance system are remained for normalizing the accuracy of the elements linear sizes with a fundamental change in the basic deviation of all tolerance intervals is the maximum deviation corresponding to the limit of the element material: EI is the lower tolerance for the of the internal elements (holes) sizes and es is the upper tolerance deviation for the outer elements (shafts) sizes. It is the sizes of the material maximum that are involved in the of the dimensional elements mating of the shafts and holes and determine the fits type.

  4. Relation between Birth Weight and Intraoperative Hemorrhage during Cesarean Section in Pregnancy with Placenta Previa

    PubMed Central

    Ishibashi, Hiroki; Takano, Masashi; Sasa, Hidenori; Furuya, Kenichi

    2016-01-01

    Background Placenta previa, one of the most severe obstetric complications, carries an increased risk of intraoperative massive hemorrhage. Several risk factors for intraoperative hemorrhage have been identified to date. However, the correlation between birth weight and intraoperative hemorrhage has not been investigated. Here we estimate the correlation between birth weight and the occurrence of intraoperative massive hemorrhage in placenta previa. Materials and Methods We included all 256 singleton pregnancies delivered via cesarean section at our hospital because of placenta previa between 2003 and 2015. We calculated not only measured birth weights but also standard deviation values according to the Japanese standard growth curve to adjust for differences in gestational age. We assessed the correlation between birth weight and the occurrence of intraoperative massive hemorrhage (>1500 mL blood loss). Receiver operating characteristic curves were constructed to determine the cutoff value of intraoperative massive hemorrhage. Results Of 256 pregnant women with placenta previa, 96 (38%) developed intraoperative massive hemorrhage. Receiver-operating characteristic curves revealed that the area under the curve of the combination variables between the standard deviation of birth weight and intraoperative massive hemorrhage was 0.71. The cutoff value with a sensitivity of 81.3% and specificity of 55.6% was −0.33 standard deviation. The multivariate analysis revealed that a standard deviation of >−0.33 (odds ratio, 5.88; 95% confidence interval, 3.04–12.00), need for hemostatic procedures (odds ratio, 3.31; 95% confidence interval, 1.79–6.25), and placental adhesion (odds ratio, 12.68; 95% confidence interval, 2.85–92.13) were independent risk of intraoperative massive hemorrhage. Conclusion In patients with placenta previa, a birth weight >−0.33 standard deviation was a significant risk indicator of massive hemorrhage during cesarean section. Based on this result, further studies are required to investigate whether fetal weight estimated by ultrasonography can predict hemorrhage during cesarean section in patients with placental previa. PMID:27902772

  5. Relation between Birth Weight and Intraoperative Hemorrhage during Cesarean Section in Pregnancy with Placenta Previa.

    PubMed

    Soyama, Hiroaki; Miyamoto, Morikazu; Ishibashi, Hiroki; Takano, Masashi; Sasa, Hidenori; Furuya, Kenichi

    2016-01-01

    Placenta previa, one of the most severe obstetric complications, carries an increased risk of intraoperative massive hemorrhage. Several risk factors for intraoperative hemorrhage have been identified to date. However, the correlation between birth weight and intraoperative hemorrhage has not been investigated. Here we estimate the correlation between birth weight and the occurrence of intraoperative massive hemorrhage in placenta previa. We included all 256 singleton pregnancies delivered via cesarean section at our hospital because of placenta previa between 2003 and 2015. We calculated not only measured birth weights but also standard deviation values according to the Japanese standard growth curve to adjust for differences in gestational age. We assessed the correlation between birth weight and the occurrence of intraoperative massive hemorrhage (>1500 mL blood loss). Receiver operating characteristic curves were constructed to determine the cutoff value of intraoperative massive hemorrhage. Of 256 pregnant women with placenta previa, 96 (38%) developed intraoperative massive hemorrhage. Receiver-operating characteristic curves revealed that the area under the curve of the combination variables between the standard deviation of birth weight and intraoperative massive hemorrhage was 0.71. The cutoff value with a sensitivity of 81.3% and specificity of 55.6% was -0.33 standard deviation. The multivariate analysis revealed that a standard deviation of >-0.33 (odds ratio, 5.88; 95% confidence interval, 3.04-12.00), need for hemostatic procedures (odds ratio, 3.31; 95% confidence interval, 1.79-6.25), and placental adhesion (odds ratio, 12.68; 95% confidence interval, 2.85-92.13) were independent risk of intraoperative massive hemorrhage. In patients with placenta previa, a birth weight >-0.33 standard deviation was a significant risk indicator of massive hemorrhage during cesarean section. Based on this result, further studies are required to investigate whether fetal weight estimated by ultrasonography can predict hemorrhage during cesarean section in patients with placental previa.

  6. Retinal nerve fiber layer thickness measured with optical coherence tomography is related to visual function in glaucomatous eyes.

    PubMed

    El Beltagi, Tarek A; Bowd, Christopher; Boden, Catherine; Amini, Payam; Sample, Pamela A; Zangwill, Linda M; Weinreb, Robert N

    2003-11-01

    To determine the relationship between areas of glaucomatous retinal nerve fiber layer thinning identified by optical coherence tomography and areas of decreased visual field sensitivity identified by standard automated perimetry in glaucomatous eyes. Retrospective observational case series. Forty-three patients with glaucomatous optic neuropathy identified by optic disc stereo photographs and standard automated perimetry mean deviations >-8 dB were included. Participants were imaged with optical coherence tomography within 6 months of reliable standard automated perimetry testing. The location and number of optical coherence tomography clock hour retinal nerve fiber layer thickness measures outside normal limits were compared with the location and number of standard automated perimetry visual field zones outside normal limits. Further, the relationship between the deviation from normal optical coherence tomography-measured retinal nerve fiber layer thickness at each clock hour and the average pattern deviation in each visual field zone was examined by using linear regression (R(2)). The retinal nerve fiber layer areas most frequently outside normal limits were the inferior and inferior temporal regions. The least sensitive visual field zones were in the superior hemifield. Linear regression results (R(2)) showed that deviation from the normal retinal nerve fiber layer thickness at optical coherence tomography clock hour positions 6 o'clock, 7 o'clock, and 8 o'clock (inferior and inferior temporal) was best correlated with standard automated perimetry pattern deviation in visual field zones corresponding to the superior arcuate and nasal step regions (R(2) range, 0.34-0.57). These associations were much stronger than those between clock hour position 6 o'clock and the visual field zone corresponding to the inferior nasal step region (R(2) = 0.01). Localized retinal nerve fiber layer thinning, measured by optical coherence tomography, is topographically related to decreased localized standard automated perimetry sensitivity in glaucoma patients.

  7. Interpreting the concordance statistic of a logistic regression model: relation to the variance and odds ratio of a continuous explanatory variable.

    PubMed

    Austin, Peter C; Steyerberg, Ewout W

    2012-06-20

    When outcomes are binary, the c-statistic (equivalent to the area under the Receiver Operating Characteristic curve) is a standard measure of the predictive accuracy of a logistic regression model. An analytical expression was derived under the assumption that a continuous explanatory variable follows a normal distribution in those with and without the condition. We then conducted an extensive set of Monte Carlo simulations to examine whether the expressions derived under the assumption of binormality allowed for accurate prediction of the empirical c-statistic when the explanatory variable followed a normal distribution in the combined sample of those with and without the condition. We also examine the accuracy of the predicted c-statistic when the explanatory variable followed a gamma, log-normal or uniform distribution in combined sample of those with and without the condition. Under the assumption of binormality with equality of variances, the c-statistic follows a standard normal cumulative distribution function with dependence on the product of the standard deviation of the normal components (reflecting more heterogeneity) and the log-odds ratio (reflecting larger effects). Under the assumption of binormality with unequal variances, the c-statistic follows a standard normal cumulative distribution function with dependence on the standardized difference of the explanatory variable in those with and without the condition. In our Monte Carlo simulations, we found that these expressions allowed for reasonably accurate prediction of the empirical c-statistic when the distribution of the explanatory variable was normal, gamma, log-normal, and uniform in the entire sample of those with and without the condition. The discriminative ability of a continuous explanatory variable cannot be judged by its odds ratio alone, but always needs to be considered in relation to the heterogeneity of the population.

  8. Automating linear accelerator quality assurance.

    PubMed

    Eckhause, Tobias; Al-Hallaq, Hania; Ritter, Timothy; DeMarco, John; Farrey, Karl; Pawlicki, Todd; Kim, Gwe-Ya; Popple, Richard; Sharma, Vijeshwar; Perez, Mario; Park, SungYong; Booth, Jeremy T; Thorwarth, Ryan; Moran, Jean M

    2015-10-01

    The purpose of this study was 2-fold. One purpose was to develop an automated, streamlined quality assurance (QA) program for use by multiple centers. The second purpose was to evaluate machine performance over time for multiple centers using linear accelerator (Linac) log files and electronic portal images. The authors sought to evaluate variations in Linac performance to establish as a reference for other centers. The authors developed analytical software tools for a QA program using both log files and electronic portal imaging device (EPID) measurements. The first tool is a general analysis tool which can read and visually represent data in the log file. This tool, which can be used to automatically analyze patient treatment or QA log files, examines the files for Linac deviations which exceed thresholds. The second set of tools consists of a test suite of QA fields, a standard phantom, and software to collect information from the log files on deviations from the expected values. The test suite was designed to focus on the mechanical tests of the Linac to include jaw, MLC, and collimator positions during static, IMRT, and volumetric modulated arc therapy delivery. A consortium of eight institutions delivered the test suite at monthly or weekly intervals on each Linac using a standard phantom. The behavior of various components was analyzed for eight TrueBeam Linacs. For the EPID and trajectory log file analysis, all observed deviations which exceeded established thresholds for Linac behavior resulted in a beam hold off. In the absence of an interlock-triggering event, the maximum observed log file deviations between the expected and actual component positions (such as MLC leaves) varied from less than 1% to 26% of published tolerance thresholds. The maximum and standard deviations of the variations due to gantry sag, collimator angle, jaw position, and MLC positions are presented. Gantry sag among Linacs was 0.336 ± 0.072 mm. The standard deviation in MLC position, as determined by EPID measurements, across the consortium was 0.33 mm for IMRT fields. With respect to the log files, the deviations between expected and actual positions for parameters were small (<0.12 mm) for all Linacs. Considering both log files and EPID measurements, all parameters were well within published tolerance values. Variations in collimator angle, MLC position, and gantry sag were also evaluated for all Linacs. The performance of the TrueBeam Linac model was shown to be consistent based on automated analysis of trajectory log files and EPID images acquired during delivery of a standardized test suite. The results can be compared directly to tolerance thresholds. In addition, sharing of results from standard tests across institutions can facilitate the identification of QA process and Linac changes. These reference values are presented along with the standard deviation for common tests so that the test suite can be used by other centers to evaluate their Linac performance against those in this consortium.

  9. Estimating error statistics for Chambon-la-Forêt observatory definitive data

    NASA Astrophysics Data System (ADS)

    Lesur, Vincent; Heumez, Benoît; Telali, Abdelkader; Lalanne, Xavier; Soloviev, Anatoly

    2017-08-01

    We propose a new algorithm for calibrating definitive observatory data with the goal of providing users with estimates of the data error standard deviations (SDs). The algorithm has been implemented and tested using Chambon-la-Forêt observatory (CLF) data. The calibration process uses all available data. It is set as a large, weakly non-linear, inverse problem that ultimately provides estimates of baseline values in three orthogonal directions, together with their expected standard deviations. For this inverse problem, absolute data error statistics are estimated from two series of absolute measurements made within a day. Similarly, variometer data error statistics are derived by comparing variometer data time series between different pairs of instruments over few years. The comparisons of these time series led us to use an autoregressive process of order 1 (AR1 process) as a prior for the baselines. Therefore the obtained baselines do not vary smoothly in time. They have relatively small SDs, well below 300 pT when absolute data are recorded twice a week - i.e. within the daily to weekly measures recommended by INTERMAGNET. The algorithm was tested against the process traditionally used to derive baselines at CLF observatory, suggesting that statistics are less favourable when this latter process is used. Finally, two sets of definitive data were calibrated using the new algorithm. Their comparison shows that the definitive data SDs are less than 400 pT and may be slightly overestimated by our process: an indication that more work is required to have proper estimates of absolute data error statistics. For magnetic field modelling, the results show that even on isolated sites like CLF observatory, there are very localised signals over a large span of temporal frequencies that can be as large as 1 nT. The SDs reported here encompass signals of a few hundred metres and less than a day wavelengths.

  10. Analytical probabilistic modeling of RBE-weighted dose for ion therapy.

    PubMed

    Wieser, H P; Hennig, P; Wahl, N; Bangert, M

    2017-11-10

    Particle therapy is especially prone to uncertainties. This issue is usually addressed with uncertainty quantification and minimization techniques based on scenario sampling. For proton therapy, however, it was recently shown that it is also possible to use closed-form computations based on analytical probabilistic modeling (APM) for this purpose. APM yields unique features compared to sampling-based approaches, motivating further research in this context. This paper demonstrates the application of APM for intensity-modulated carbon ion therapy to quantify the influence of setup and range uncertainties on the RBE-weighted dose. In particular, we derive analytical forms for the nonlinear computations of the expectation value and variance of the RBE-weighted dose by propagating linearly correlated Gaussian input uncertainties through a pencil beam dose calculation algorithm. Both exact and approximation formulas are presented for the expectation value and variance of the RBE-weighted dose and are subsequently studied in-depth for a one-dimensional carbon ion spread-out Bragg peak. With V and B being the number of voxels and pencil beams, respectively, the proposed approximations induce only a marginal loss of accuracy while lowering the computational complexity from order [Formula: see text] to [Formula: see text] for the expectation value and from [Formula: see text] to [Formula: see text] for the variance of the RBE-weighted dose. Moreover, we evaluated the approximated calculation of the expectation value and standard deviation of the RBE-weighted dose in combination with a probabilistic effect-based optimization on three patient cases considering carbon ions as radiation modality against sampled references. The resulting global γ-pass rates (2 mm,2%) are [Formula: see text]99.15% for the expectation value and [Formula: see text]94.95% for the standard deviation of the RBE-weighted dose, respectively. We applied the derived analytical model to carbon ion treatment planning, although the concept is in general applicable to other ion species considering a variable RBE.

  11. Flying Under the LiDAR: Relating Forest Structure to Bat Community Diversity

    NASA Astrophysics Data System (ADS)

    Swanson, A. C.; Weishampel, J. F.

    2015-12-01

    Bats are important to many ecological processes such as pollination, insect (and by proxy, disease) control, and seed dispersal and can be used to monitor ecosystem health. However, they are facing unprecedented extinction risks from habitat degradation as well as pressures from pathogens (e.g., white-nose syndrome) and wind turbines. LiDAR allows ecologists to measure structural variables of forested landscapes with increased precision and accuracy at broader spatial scales than previously possible. This study used airborne LiDAR to classify forest habitat/canopy structure at the Ordway-Swisher Biological Station (OSBS) in north central Florida. LiDAR data were acquired by the NEON airborne observation platform in summer 2014. OSBS consists of open-canopy pine savannas, closed-canopy hardwood hammocks, and seasonally wet prairies. Multiple forest structural parameters (e.g., mean, maximum, and standard deviation of height returns) were derived from LiDAR point clouds using the USDA software program FUSION. K-means clustering was used to segregate each 5x5 m raster across the ~3765 ha OSBS area into six different clusters based on the derived canopy metrics. Cluster averages for maximum, mean, and standard deviation of return heights ranged from 0 to 19.4 m, 0 to 15.3 m, and 0 to 3.0 m, respectively. To determine the relationships among these landscape-canopy features and bat species diversity and abundances, AnaBat II bat detectors were deployed from May to September in 2015 stratified by these distinct clusters. Bat calls were recorded from sunset to sunrise during each sampling period. Species were identified using AnalookW. A statistical regression model selection approach was performed in order to evaluate how forest attributes such as understory clutter, open regions, open and closed canopy, etc. influence bat communities. This knowledge provides a deeper understanding of habitat-species interactions to better manage survival of these species.

  12. Analytical probabilistic modeling of RBE-weighted dose for ion therapy

    NASA Astrophysics Data System (ADS)

    Wieser, H. P.; Hennig, P.; Wahl, N.; Bangert, M.

    2017-12-01

    Particle therapy is especially prone to uncertainties. This issue is usually addressed with uncertainty quantification and minimization techniques based on scenario sampling. For proton therapy, however, it was recently shown that it is also possible to use closed-form computations based on analytical probabilistic modeling (APM) for this purpose. APM yields unique features compared to sampling-based approaches, motivating further research in this context. This paper demonstrates the application of APM for intensity-modulated carbon ion therapy to quantify the influence of setup and range uncertainties on the RBE-weighted dose. In particular, we derive analytical forms for the nonlinear computations of the expectation value and variance of the RBE-weighted dose by propagating linearly correlated Gaussian input uncertainties through a pencil beam dose calculation algorithm. Both exact and approximation formulas are presented for the expectation value and variance of the RBE-weighted dose and are subsequently studied in-depth for a one-dimensional carbon ion spread-out Bragg peak. With V and B being the number of voxels and pencil beams, respectively, the proposed approximations induce only a marginal loss of accuracy while lowering the computational complexity from order O(V × B^2) to O(V × B) for the expectation value and from O(V × B^4) to O(V × B^2) for the variance of the RBE-weighted dose. Moreover, we evaluated the approximated calculation of the expectation value and standard deviation of the RBE-weighted dose in combination with a probabilistic effect-based optimization on three patient cases considering carbon ions as radiation modality against sampled references. The resulting global γ-pass rates (2 mm,2%) are > 99.15% for the expectation value and > 94.95% for the standard deviation of the RBE-weighted dose, respectively. We applied the derived analytical model to carbon ion treatment planning, although the concept is in general applicable to other ion species considering a variable RBE.

  13. A cross-scale approach to understand drought-induced variability of sagebrush ecosystem productivity

    NASA Astrophysics Data System (ADS)

    Assal, T.; Anderson, P. J.

    2016-12-01

    Sagebrush (Artemisia spp.) mortality has recently been reported in the Upper Green River Basin (Wyoming, USA) of the sagebrush steppe of western North America. Numerous causes have been suggested, but recent drought (2012-13) is the likely mechanism of mortality in this water-limited ecosystem which provides critical habitat for many species of wildlife. An understanding of the variability in patterns of productivity with respect to climate is essential to exploit landscape scale remote sensing for detection of subtle changes associated with mortality in this sparse, uniformly vegetated ecosystem. We used the standardized precipitation index to characterize drought conditions and Moderate Resolution Imaging Spectroradiometer (MODIS) satellite imagery (250-m resolution) to characterize broad characteristics of growing season productivity. We calculated per-pixel growing season anomalies over a 16-year period (2000-2015) to identify the spatial and temporal variability in productivity. Metrics derived from Landsat satellite imagery (30-m resolution) were used to further investigate trends within anomalous areas at local scales. We found evidence to support an initial hypothesis that antecedent winter drought was most important in explaining reduced productivity. The results indicate drought effects were inconsistent over space and time. MODIS derived productivity deviated by more than four standard deviations in heavily impacted areas, but was well within the interannual variability in other areas. Growing season anomalies highlighted dramatic declines in productivity during the 2012 and 2013 growing seasons. However, large negative anomalies persisted in other areas during the 2014 growing season, indicating lag effects of drought. We are further investigating if the reduction in productivity is mediated by local biophysical properties. Our analysis identified spatially explicit patterns of ecosystem properties altered by severe drought which are consistent with field observations of sagebrush mortality. The results provide a theoretical framework for future field based investigation at multiple spatiotemporal scales.

  14. Validated method for quantification of genetically modified organisms in samples of maize flour.

    PubMed

    Kunert, Renate; Gach, Johannes S; Vorauer-Uhl, Karola; Engel, Edwin; Katinger, Hermann

    2006-02-08

    Sensitive and accurate testing for trace amounts of biotechnology-derived DNA from plant material is the prerequisite for detection of 1% or 0.5% genetically modified ingredients in food products or raw materials thereof. Compared to ELISA detection of expressed proteins, real-time PCR (RT-PCR) amplification has easier sample preparation and detection limits are lower. Of the different methods of DNA preparation CTAB method with high flexibility in starting material and generation of sufficient DNA with relevant quality was chosen. Previous RT-PCR data generated with the SYBR green detection method showed that the method is highly sensitive to sample matrices and genomic DNA content influencing the interpretation of results. Therefore, this paper describes a real-time DNA quantification based on the TaqMan probe method, indicating high accuracy and sensitivity with detection limits of lower than 18 copies per sample applicable and comparable to highly purified plasmid standards as well as complex matrices of genomic DNA samples. The results were evaluated with ValiData for homology of variance, linearity, accuracy of the standard curve, and standard deviation.

  15. Constraints on non-Standard Model Higgs boson interactions in an effective Lagrangian using differential cross sections measured in the H→γγ decay channel at \\(\\sqrt{s} = 8\\) TeV with the ATLAS detector

    DOE PAGES

    Aad, G.

    2015-12-02

    The strength and tensor structure of the Higgs boson's interactions are investigated using an effective Lagrangian, which introduces additional CP-even and CP-odd interactions that lead to changes in the kinematic properties of the Higgs boson and associated jet spectra with respect to the Standard Model. We found that the parameters of the effective Lagrangian are probed using a fit to five differential cross sections previously measured by the ATLAS experiment in the H→γγ decay channel with an integrated luminosity of 20.3 fb -1 at \\(\\sqrt{s} = 8\\) TeV. In order to perform a simultaneous fit to the five distributions, themore » statistical correlations between them are determined by re-analysing the H→γγ candidate events in the proton–proton collision data. No significant deviations from the Standard Model predictions are observed and limits on the effective Lagrangian parameters are derived. These statistical correlations are made publicly available to allow for future analysis of theories with non-Standard Model interactions.« less

  16. Constraints on non-Standard Model Higgs boson interactions in an effective Lagrangian using differential cross sections measured in the H→γγ decay channel at \\(\\sqrt{s} = 8\\) TeV with the ATLAS detector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aad, G.

    The strength and tensor structure of the Higgs boson's interactions are investigated using an effective Lagrangian, which introduces additional CP-even and CP-odd interactions that lead to changes in the kinematic properties of the Higgs boson and associated jet spectra with respect to the Standard Model. We found that the parameters of the effective Lagrangian are probed using a fit to five differential cross sections previously measured by the ATLAS experiment in the H→γγ decay channel with an integrated luminosity of 20.3 fb -1 at \\(\\sqrt{s} = 8\\) TeV. In order to perform a simultaneous fit to the five distributions, themore » statistical correlations between them are determined by re-analysing the H→γγ candidate events in the proton–proton collision data. No significant deviations from the Standard Model predictions are observed and limits on the effective Lagrangian parameters are derived. These statistical correlations are made publicly available to allow for future analysis of theories with non-Standard Model interactions.« less

  17. The Validity of IQ Scores Derived from Readiness Screening Tests

    ERIC Educational Resources Information Center

    Telegdy, Gabriel A.

    1976-01-01

    The Screening Test of Academic Readiness (STAR) and the Peabody Picture Vocabulary Test (PPVT) were administered to 52 kindergarten children to reveal the convergent validity of IQ scores derived from the STAR. The findings raise doubts about the validity of the deviation IQs derived from the STAR. (Author)

  18. Comparing Derived and Actual Upwelling Longwave Measurements at the CERES Ocean Validation Experiment (COVE)

    NASA Astrophysics Data System (ADS)

    Fabbri, B. E.; Schuster, G. L.; Denn, F. M.; Arduini, R. F.; Madigan, J. J.

    2017-12-01

    One of the parameters measured from the Clouds and the Earth's Radiant Energy System (CERES) satellite is Earth emitted or longwave (LW) radiation. One validation site to compare this quantity is the CERES Ocean Validation Experiment (COVE), located at Chesapeake Light Station, approximately 25 kilometers east of Virginia Beach, Virginia (coordinates: 36.90N, 75.71W). However, the upwelling measurement is complicated due to the Light Station tower being in the LW instruments field of view. A negative outcome of the tower being in the field of view is a tower radiating effect, especially noticeable on clear, sunny days. During these days, the tower tends to heat up and radiate extra heat energy that is measured by the LW instrument. To understand the extent of the problem, we derive upwelling longwave measurements at the surface using sea surface temperature, air temperature, and dewpoint to compare with the actual longwave measurement made with an Eppley Laboratory pyrgeometer. The data used in this study is over a four-year period (2009-2012). One result using only nighttime data (range: 15.0 =< sa <= 55.0) shows the relative error between actual versus derived being low. The resultant statistics produced a mean, median, standard deviation and standard error to be -0.378, -0.14, 1.906 and 0.005 respectively. This low error is not too surprising since there is no solar insolation creating the tower radiating effect. Other results comparing the diurnal scope are analyzed and presented.

  19. Density Large Deviations for Multidimensional Stochastic Hyperbolic Conservation Laws

    NASA Astrophysics Data System (ADS)

    Barré, J.; Bernardin, C.; Chetrite, R.

    2018-02-01

    We investigate the density large deviation function for a multidimensional conservation law in the vanishing viscosity limit, when the probability concentrates on weak solutions of a hyperbolic conservation law. When the mobility and diffusivity matrices are proportional, i.e. an Einstein-like relation is satisfied, the problem has been solved in Bellettini and Mariani (Bull Greek Math Soc 57:31-45, 2010). When this proportionality does not hold, we compute explicitly the large deviation function for a step-like density profile, and we show that the associated optimal current has a non trivial structure. We also derive a lower bound for the large deviation function, valid for a more general weak solution, and leave the general large deviation function upper bound as a conjecture.

  20. [The scale and application of the norm of occupational stress on the professionals in Chengdu and Chongqing area].

    PubMed

    Zeng, Fan-Hua; Wang, Zhi-Ming; Wang, Mian-Zhen; Lan, Ya-Jia

    2004-12-01

    To establish the scale of the norm of occupational stress on the professionals and put it into practice. T scores were linear transformations of raw scores, derived to have a mean of 50 and a standard deviation of 10. The scale standard of the norm was formulated in line with the principle of normal distribution. (1) For the occupational role questionnaire (ORQ) and personal strain questionnaire (PSQ) scales, high scores suggested significant levels of occupational stress and psychological strain, respectively. T scores >/= 70 indicated a strong probability of maladaptive stress, debilitating strain, or both. T scores in 60 approximately 69 suggested mild levels of maladaptive stress and strain, and in 40 approximately 59 were within one standard deviation of the mean and should be interpreted as being within normal range. T scores < 40 indicated a relative absence of occupational stress or psychological strain. For the personal resources questionnaire (PRQ) scales, high scores indicated highly developed coping resources. T scores < 30 indicated a significant lack of coping resources. T scores in 30 approximately 39 suggested mild deficits in coping skills, and in 40 approximately 59 indicated average coping resources, where as higher scores (i.e., >/= 60) indicated increasingly strong coping resources. (2) This study provided raw score to T-score conversion tables for each OSI-R scale for the total normative sample as well as for gender, and several occupational groups, including professional engineer, professional health care, economic business, financial business, law, education and news. OSI-R profile forms for total normative samples, gender and occupation were also offered according to the conversion tables. The norm of occupational stress can be used as screening tool, organizational/occupational assessment, guide to occupational choice and intervention measures.

  1. In vivo dosimetry for external photon treatments of head and neck cancers by diodes and TLDS.

    PubMed

    Tung, C J; Wang, H C; Lo, S H; Wu, J M; Wang, C J

    2004-01-01

    In vivo dosimetry was implemented for treatments of head and neck cancers in the large fields. Diode and thermoluminescence dosemeter (TLD) measurements were carried out for the linear accelerators of 6 MV photon beams. ESTRO in vivo dosimetry protocols were followed in the determination of midline doses from measurements of entrance and exit doses. Of the fields monitored by diodes, the maximum absolute deviation of measured midline doses from planned target doses was 8%, with the mean value and the standard deviation of -1.0 and 2.7%. If planned target doses were calculated using radiological water equivalent thicknesses rather than patient geometric thicknesses, the maximum absolute deviation dropped to 4%, with the mean and the standard deviation of 0.7 and 1.8%. For in vivo dosimetry monitored by TLDs, the shift in mean dose remained small but the statistical precision became poor.

  2. A visual tristimulus projection colorimeter.

    PubMed

    Valberg, A

    1971-01-01

    Based on the optical principle of a slide projector, a visual tristimulus projection colorimeter has been developed. The calorimeter operates with easily interchangeable sets of primary color filters placed in a frame at the objective. The apparatus has proved to be fairly accurate. The reproduction of the color matches as measured by the standard deviation is equal to the visual sensitivity to color differences for each observer. Examples of deviations in the matches among individuals as well as deviations compared with the CIE 1931 Standard Observer are given. These deviations are demonstrated to be solely due to individual differences in the perception of metameric colors. Thus, taking advantage of an objective observation (allowing all adjustments to be judged by a group of impartial observers), the colorimeter provides an excellent aid in the study of discrimination, metamerism, and related effects which are of considerable interest in current research in colorimetry and in the study of color vision tests.

  3. Discriminating crop and other canopies by overlapping binary image layers

    NASA Astrophysics Data System (ADS)

    Doi, Ryoichi

    2013-02-01

    For optimal management of agricultural fields by remote sensing, discrimination of the crop canopy from weeds and other objects is essential. In a digital photograph, a rice canopy was discriminated from a variety of weed and tree canopies and other objects by overlapping binary image layers of red-green-blue and other color components indicating the pixels with target canopy-specific (intensity) values based on the ranges of means ±(3×) standard deviations. By overlapping and merging the binary image layers, the target canopy specificity improved to 0.0015 from 0.027 for the yellow 1× standard deviation binary image layer, which was the best among all combinations of color components and means ±(3×) standard deviations. The most target rice canopy-likely pixels were further identified by limiting the pixels at different luminosity values. The discriminatory power was also visually demonstrated in this manner.

  4. Middle school transition and body weight outcomes: Evidence from Arkansas Public Schoolchildren.

    PubMed

    Zeng, Di; Thomsen, Michael R; Nayga, Rodolfo M; Rouse, Heather L

    2016-05-01

    There is evidence that middle school transition adversely affects educational and psychological outcomes of pre-teen children, but little is known about the impacts of middle school transition on other aspects of health. In this article, we estimate the impact of middle school transition on the body mass index (BMI) of public schoolchildren in Arkansas, United States. Using an instrumental variable approach, we find that middle school transition in grade 6 led to a moderate decrease of 0.04 standard deviations in BMI z-scores for all students. Analysis by subsample indicated that this result was driven by boys (0.06-0.07 standard deviations) and especially by non-minority boys (0.09 standard deviations). We speculate that the changing levels of physical activities associated with middle school transition provide the most reasonable explanation for this result. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Migration in the shearing sheet and estimates for young open cluster migration

    NASA Astrophysics Data System (ADS)

    Quillen, Alice C.; Nolting, Eric; Minchev, Ivan; De Silva, Gayandhi; Chiappini, Cristina

    2018-04-01

    Using tracer particles embedded in self-gravitating shearing sheet N-body simulations, we investigate the distance in guiding centre radius that stars or star clusters can migrate in a few orbital periods. The standard deviations of guiding centre distributions and maximum migration distances depend on the Toomre or critical wavelength and the contrast in mass surface density caused by spiral structure. Comparison between our simulations and estimated guiding radii for a few young supersolar metallicity open clusters, including NGC 6583, suggests that the contrast in mass surface density in the solar neighbourhood has standard deviation (in the surface density distribution) divided by mean of about 1/4 and larger than measured using COBE data by Drimmel and Spergel. Our estimate is consistent with a standard deviation of ˜0.07 dex in the metallicities measured from high-quality spectroscopic data for 38 young open clusters (<1 Gyr) with mean galactocentric radius 7-9 kpc.

  6. The Cost of Uncertain Life Span*

    PubMed Central

    Edwards, Ryan D.

    2012-01-01

    A considerable amount of uncertainty surrounds the length of human life. The standard deviation in adult life span is about 15 years in the U.S., and theory and evidence suggest it is costly. I calibrate a utility-theoretic model of preferences over length of life and show that one fewer year in standard deviation is worth about half a mean life year. Differences in the standard deviation exacerbate cross-sectional differences in life expectancy between the U.S. and other industrialized countries, between rich and poor countries, and among poor countries. Accounting for the cost of life-span variance also appears to amplify recently discovered patterns of convergence in world average human well-being. This is partly for methodological reasons and partly because unconditional variance in human length of life, primarily the component due to infant mortality, has exhibited even more convergence than life expectancy. PMID:22368324

  7. On the linear relation between the mean and the standard deviation of a response time distribution.

    PubMed

    Wagenmakers, Eric-Jan; Brown, Scott

    2007-07-01

    Although it is generally accepted that the spread of a response time (RT) distribution increases with the mean, the precise nature of this relation remains relatively unexplored. The authors show that in several descriptive RT distributions, the standard deviation increases linearly with the mean. Results from a wide range of tasks from different experimental paradigms support a linear relation between RT mean and RT standard deviation. Both R. Ratcliff's (1978) diffusion model and G. D. Logan's (1988) instance theory of automatization provide explanations for this linear relation. The authors identify and discuss 3 specific boundary conditions for the linear law to hold. The law constrains RT models and supports the use of the coefficient of variation to (a) compare variability while controlling for differences in baseline speed of processing and (b) assess whether changes in performance with practice are due to quantitative speedup or qualitative reorganization. Copyright 2007 APA.

  8. Quantifying relative importance: Computing standardized effects in models with binary outcomes

    USGS Publications Warehouse

    Grace, James B.; Johnson, Darren; Lefcheck, Jonathan S.; Byrnes, Jarrett E.K.

    2018-01-01

    Results from simulation studies show that both the LT and OE methods of standardization support a similarly-broad range of coefficient comparisons. The LT method estimates effects that reflect underlying latent-linear propensities, while the OE method computes a linear approximation for the effects of predictors on binary responses. The contrast between assumptions for the two methods is reflected in persistently weaker standardized effects associated with OE standardization. Reliance on standard deviations for standardization (the traditional approach) is critically examined and shown to introduce substantial biases when predictors are non-Gaussian. The use of relevant ranges in place of standard deviations has the capacity to place LT and OE standardized coefficients on a more comparable scale. As ecologists address increasingly complex hypotheses, especially those that involve comparing the influences of different controlling factors (e.g., top-down versus bottom-up or biotic versus abiotic controls), comparable coefficients become a necessary component for evaluations.

  9. On the variability of the Priestley-Taylor coefficient over water bodies

    NASA Astrophysics Data System (ADS)

    Assouline, Shmuel; Li, Dan; Tyler, Scott; Tanny, Josef; Cohen, Shabtai; Bou-Zeid, Elie; Parlange, Marc; Katul, Gabriel G.

    2016-01-01

    Deviations in the Priestley-Taylor (PT) coefficient αPT from its accepted 1.26 value are analyzed over large lakes, reservoirs, and wetlands where stomatal or soil controls are minimal or absent. The data sets feature wide variations in water body sizes and climatic conditions. Neither surface temperature nor sensible heat flux variations alone, which proved successful in characterizing αPT variations over some crops, explain measured deviations in αPT over water. It is shown that the relative transport efficiency of turbulent heat and water vapor is key to explaining variations in αPT over water surfaces, thereby offering a new perspective over the concept of minimal advection or entrainment introduced by PT. Methods that allow the determination of αPT based on low-frequency sampling (i.e., 0.1 Hz) are then developed and tested, which are usable with standard meteorological sensors that filter some but not all turbulent fluctuations. Using approximations to the Gram determinant inequality, the relative transport efficiency is derived as a function of the correlation coefficient between temperature and water vapor concentration fluctuations (RTq). The proposed approach reasonably explains the measured deviations from the conventional αPT = 1.26 value even when RTq is determined from air temperature and water vapor concentration time series that are Gaussian-filtered and subsampled to a cutoff frequency of 0.1 Hz. Because over water bodies, RTq deviations from unity are often associated with advection and/or entrainment, linkages between αPT and RTq offer both a diagnostic approach to assess their significance and a prognostic approach to correct the 1.26 value when using routine meteorological measurements of temperature and humidity.

  10. Precision measurement of the weak charge of the proton.

    PubMed

    2018-05-01

    Large experimental programmes in the fields of nuclear and particle physics search for evidence of physics beyond that explained by current theories. The observation of the Higgs boson completed the set of particles predicted by the standard model, which currently provides the best description of fundamental particles and forces. However, this theory's limitations include a failure to predict fundamental parameters, such as the mass of the Higgs boson, and the inability to account for dark matter and energy, gravity, and the matter-antimatter asymmetry in the Universe, among other phenomena. These limitations have inspired searches for physics beyond the standard model in the post-Higgs era through the direct production of additional particles at high-energy accelerators, which have so far been unsuccessful. Examples include searches for supersymmetric particles, which connect bosons (integer-spin particles) with fermions (half-integer-spin particles), and for leptoquarks, which mix the fundamental quarks with leptons. Alternatively, indirect searches using precise measurements of well predicted standard-model observables allow highly targeted alternative tests for physics beyond the standard model because they can reach mass and energy scales beyond those directly accessible by today's high-energy accelerators. Such an indirect search aims to determine the weak charge of the proton, which defines the strength of the proton's interaction with other particles via the well known neutral electroweak force. Because parity symmetry (invariance under the spatial inversion (x, y, z) → (-x, -y, -z)) is violated only in the weak interaction, it provides a tool with which to isolate the weak interaction and thus to measure the proton's weak charge 1 . Here we report the value 0.0719 ± 0.0045, where the uncertainty is one standard deviation, derived from our measured parity-violating asymmetry in the scattering of polarized electrons on protons, which is -226.5 ± 9.3 parts per billion (the uncertainty is one standard deviation). Our value for the proton's weak charge is in excellent agreement with the standard model 2 and sets multi-teraelectronvolt-scale constraints on any semi-leptonic parity-violating physics not described within the standard model. Our results show that precision parity-violating measurements enable searches for physics beyond the standard model that can compete with direct searches at high-energy accelerators and, together with astronomical observations, can provide fertile approaches to probing higher mass scales.

  11. Response surface optimized peroxyoxalate chemiluminescence of octahydro-Schiff base derivative as new luminophor and study of the quenching effect of some cations, amino acids and cholesterol.

    PubMed

    Yeganeh Faal, Ali; Jamalyan, Bahare; Bordbar, Maryam; Shayeste, Tavakol Heidary; Salavati-Niasari, Masoud

    2014-12-01

    We report the first detailed study of the characteristics of an octahydro-Schiff base derivative as a new luminophor in the peroxyoxalate chemiluminescence (POCL) system. The effect of reagents on this new POCL system was investigated. In addition, the response surface methodology was used for evaluating the relative significance of variables in this POCL system, establishing models and determining optimal conditions. The quenching effect of some cations and compounds such as Cu(2+), Fe(3+), Hg(2+), imidazole, histidine and cholesterol on an optimized POCL reaction were studied. The dynamic ranges were up to approximaterly 100 and 175 × 10(-6) M for Cu(2+) and cholesterol respectively. The detection limits were 3.3 × 10(-6) m and 2.58 × 10(-6) m for Cu(2+) and histidine, respectively. In all cases the relative standard deviations were 4-5% (n = 4). Copyright © 2014 John Wiley & Sons, Ltd.

  12. Automatic Differentiation in Quantum Chemistry with Applications to Fully Variational Hartree-Fock.

    PubMed

    Tamayo-Mendoza, Teresa; Kreisbeck, Christoph; Lindh, Roland; Aspuru-Guzik, Alán

    2018-05-23

    Automatic differentiation (AD) is a powerful tool that allows calculating derivatives of implemented algorithms with respect to all of their parameters up to machine precision, without the need to explicitly add any additional functions. Thus, AD has great potential in quantum chemistry, where gradients are omnipresent but also difficult to obtain, and researchers typically spend a considerable amount of time finding suitable analytical forms when implementing derivatives. Here, we demonstrate that AD can be used to compute gradients with respect to any parameter throughout a complete quantum chemistry method. We present DiffiQult , a Hartree-Fock implementation, entirely differentiated with the use of AD tools. DiffiQult is a software package written in plain Python with minimal deviation from standard code which illustrates the capability of AD to save human effort and time in implementations of exact gradients in quantum chemistry. We leverage the obtained gradients to optimize the parameters of one-particle basis sets in the context of the floating Gaussian framework.

  13. Error simulation of paired-comparison-based scaling methods

    NASA Astrophysics Data System (ADS)

    Cui, Chengwu

    2000-12-01

    Subjective image quality measurement usually resorts to psycho physical scaling. However, it is difficult to evaluate the inherent precision of these scaling methods. Without knowing the potential errors of the measurement, subsequent use of the data can be misleading. In this paper, the errors on scaled values derived form paired comparison based scaling methods are simulated with randomly introduced proportion of choice errors that follow the binomial distribution. Simulation results are given for various combinations of the number of stimuli and the sampling size. The errors are presented in the form of average standard deviation of the scaled values and can be fitted reasonably well with an empirical equation that can be sued for scaling error estimation and measurement design. The simulation proves paired comparison based scaling methods can have large errors on the derived scaled values when the sampling size and the number of stimuli are small. Examples are also given to show the potential errors on actually scaled values of color image prints as measured by the method of paired comparison.

  14. Visual detection and sequential injection determination of aluminium using a cinnamoyl derivative.

    PubMed

    Elečková, Lenka; Alexovič, Michal; Kuchár, Juraj; Balogh, Ioseph S; Andruch, Vasil

    2015-02-01

    A cinnamoyl derivative, 3-[4-(dimethylamino)cinnamoyl]-4-hydroxy-6-methyl-3,4-2H-pyran-2-one, was used as a ligand for the determination of aluminium. Upon the addition of an acetonitrile solution of the ligand to an aqueous solution containing Al(III) and a buffer solution at pH 8, a marked change in colour from yellow to orange is observed. The colour intensity is proportional to the concentration of Al(III); thus, the 'naked-eye' detection of aluminium is possible. The reaction is also applied for sequential injection determination of aluminium. Beer׳s law is obeyed in the range from 0.055 to 0.66 mg L(-1) of Al(III). The limit of detection, calculated as three times the standard deviation of the blank test (n=10), was found to be 4 μg L(-1) for Al(III). The method was applied for the determination of aluminium in spiked water samples and pharmaceutical preparations. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Analysis of the coriolis interaction of the ν12 band with 2 ν10 of cis-d 2-ethylene by high-resolution Fourier transform infrared spectroscopy

    NASA Astrophysics Data System (ADS)

    Goh, K. L.; Tan, T. L.; Ong, P. P.; Teo, H. H.

    2000-08-01

    The Fourier transform infrared spectrum of the ν12 band of cis-d 2-ethylene ( cis-C 2H 2D 2) has been recorded with an unapodized resolution of 0.0024 cm -1 in the frequency range of 1280-1400 cm -1. This band was found to be mutually coupled by Coriolis interaction with the unobserved 2 ν10 band situated approximately 10 cm -1 below ν12. By fitting a total of 771 infrared transitions of ν12 with a standard deviation of 0.00075 cm -1 using the Watson's Hamiltonian with the inclusion of a c-type Coriolis resonance term, a set of accurate rovibrational constants for V 12=1 state was derived. The ν12 band is A type with a band centre at 1341.1512±0.0001 cm -1. Accurate rovibrational constants for the V 10=2 state were also derived.

  16. Correlation of track irregularities and vehicle responses based on measured data

    NASA Astrophysics Data System (ADS)

    Karis, Tomas; Berg, Mats; Stichel, Sebastian; Li, Martin; Thomas, Dirk; Dirks, Babette

    2018-06-01

    Track geometry quality and dynamic vehicle response are closely related, but do not always correspond with each other in terms of maximum values and standard deviations. This can often be seen to give poor results in analyses with correlation coefficients or regression analysis. Measured data from both the EU project DynoTRAIN and the Swedish Green Train (Gröna Tåget) research programme is used in this paper to evaluate track-vehicle response for three vehicles. A single degree of freedom model is used as an inspiration to divide track-vehicle interaction into three parts, which are analysed in terms of correlation. One part, the vertical axle box acceleration divided by vehicle speed squared (?) and the second spatial derivative of the vertical track irregularities (?), is shown to be the weak link with lower correlation coefficients than the other parts. Future efforts should therefore be directed towards investigating the relation between axle box accelerations and track irregularity second derivatives.

  17. Neutral monosaccharide composition analysis of plant-derived oligo- and polysaccharides by high performance liquid chromatography.

    PubMed

    Yan, Jun; Shi, Songshan; Wang, Hongwei; Liu, Ruimin; Li, Ning; Chen, Yonglin; Wang, Shunchun

    2016-01-20

    A novel analytical method for neutral monosaccharide composition analysis of plant-derived oligo- and polysaccharides was developed using hydrophilic interaction liquid chromatography coupled to a charged aerosol detector. The effects of column type, additives, pH and column temperature on retention and separation were evaluated. Additionally, the method could distinguish potential impurities in samples, including chloride, sulfate and sodium, from sugars. The results of validation demonstrated that this method had good linearity (R(2) ≥ 0.9981), high precision (relative standard deviation ≤ 4.43%), and adequate accuracy (94.02-103.37% recovery) and sensitivity (detection limit: 15-40 ng). Finally, the monosaccharide compositions of the polysaccharide from Eclipta prostrasta L. and stachyose were successfully profiled through this method. This report represents the first time that all of these common monosaccharides could be well-separated and determined simultaneously by high performance liquid chromatography without additional derivatization. This newly developed method is convenient, efficient and reliable for monosaccharide analysis. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Abelian F-theory models with charge-3 and charge-4 matter

    NASA Astrophysics Data System (ADS)

    Raghuram, Nikhil

    2018-05-01

    This paper analyzes U(1) F-theory models admitting matter with charges q = 3 and 4. First, we systematically derive a q = 3 construction that generalizes the previous q = 3 examples. We argue that U(1) symmetries can be tuned through a procedure reminiscent of the SU( N ) and Sp( N ) tuning process. For models with q = 3 matter, the components of the generating section vanish to orders higher than 1 at the charge-3 matter loci. As a result, the Weierstrass models can contain non-UFD structure and thereby deviate from the standard Morrison-Park form. Techniques used to tune SU( N ) models on singular divisors allow us to determine the non-UFD structures and derive the q = 3 tuning from scratch. We also obtain a class of a q=4 models by deforming a prior U(1) × U(1) construction. To the author's knowledge, this is the first published F-theory example with charge-4 matter. Finally, we discuss some conjectures regarding models with charges larger than 4.

  19. Creep Behavior of Passive Bovine Extraocular Muscle

    PubMed Central

    Yoo, Lawrence; Kim, Hansang; Shin, Andrew; Gupta, Vijay; Demer, Joseph L.

    2011-01-01

    This paper characterized bovine extraocular muscles (EOMs) using creep, which represents long-term stretching induced by a constant force. After preliminary optimization of testing conditions, 20 fresh EOM samples were subjected to four different loading rates of 1.67, 3.33, 8.33, and 16.67%/s, after which creep was observed for 1,500 s. A published quasilinear viscoelastic (QLV) relaxation function was transformed to a creep function that was compared with data. Repeatable creep was observed for each loading rate and was similar among all six anatomical EOMs. The mean creep coefficient after 1,500 seconds for a wide range of initial loading rates was at 1.37 ± 0.03 (standard deviation, SD). The creep function derived from the relaxation-based QLV model agreed with observed creep to within 2.7% following 16.67%/s ramp loading. Measured creep agrees closely with a derived QLV model of EOM relaxation, validating a previous QLV model for characterization of EOM biomechanics. PMID:22131809

  20. NGA-West 2 Equations for predicting PGA, PGV, and 5%-Damped PSA for shallow crustal earthquakes

    USGS Publications Warehouse

    Boore, David M.; Stewart, Jon P.; Seyhan, Emel; Atkinson, Gail M.

    2013-01-01

    We provide ground-motion prediction equations for computing medians and standard deviations of average horizontal component intensity measures (IMs) for shallow crustal earthquakes in active tectonic regions. The equations were derived from a global database with M 3.0–7.9 events. We derived equations for the primary M- and distance-dependence of the IMs after fixing the VS30-based nonlinear site term from a parallel NGA-West 2 study. We then evaluated additional effects using mixed effects residuals analysis, which revealed no trends with source depth over the M range of interest, indistinct Class 1 and 2 event IMs, and basin depth effects that increase and decrease long-period IMs for depths larger and smaller, respectively, than means from regional VS30-depth relations. Our aleatory variability model captures decreasing between-event variability with M, as well as within-event variability that increases or decreases with M depending on period, increases with distance, and decreases for soft sites.

  1. Automatic Differentiation in Quantum Chemistry with Applications to Fully Variational Hartree–Fock

    PubMed Central

    2018-01-01

    Automatic differentiation (AD) is a powerful tool that allows calculating derivatives of implemented algorithms with respect to all of their parameters up to machine precision, without the need to explicitly add any additional functions. Thus, AD has great potential in quantum chemistry, where gradients are omnipresent but also difficult to obtain, and researchers typically spend a considerable amount of time finding suitable analytical forms when implementing derivatives. Here, we demonstrate that AD can be used to compute gradients with respect to any parameter throughout a complete quantum chemistry method. We present DiffiQult, a Hartree–Fock implementation, entirely differentiated with the use of AD tools. DiffiQult is a software package written in plain Python with minimal deviation from standard code which illustrates the capability of AD to save human effort and time in implementations of exact gradients in quantum chemistry. We leverage the obtained gradients to optimize the parameters of one-particle basis sets in the context of the floating Gaussian framework.

  2. Reduced Bone Cortical Thickness in Boys with Autism or Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Hediger, Mary L.; England, Lucinda J.; Molloy, Cynthia A.; Yu, Kai F.; Manning-Courtney, Patricia; Mills, James L.

    2008-01-01

    Bone development, casein-free diet use, supplements, and medications were assessed for 75 boys with autism or autism spectrum disorder, ages 4-8 years. Second metacarpal bone cortical thickness (BCT), measured on hand-wrist radiographs, and % deviations in BCT from reference medians were derived. BCT increased with age, but % deviations evidenced…

  3. A search for squarks of Rp-violating SUSY at HERA

    NASA Astrophysics Data System (ADS)

    Aid, S.; Andreev, V.; Andrieu, B.; Appuhn, R. D.; Arpagaus, M.; Babaev, A.; Bähr, J.; Bán, J.; Ban, Y.; Baranov, P.; Barrelet, E.; Barschke, R.; Bartel, W.; Barth, M.; Bassler, U.; Beck, H. P.; Behrend, H. J.; Belousov, A.; Berger, Ch.; Bernardi, G.; Bernet, R.; Bertrand-Coremans, G.; Besançon, M.; Beyer, R.; Biddulph, P.; Bispham, P.; Bizot, J. C.; Blobel, V.; Borras, K.; Botterweck, F.; Boudry, V.; Braemer, A.; Braunschweig, W.; Brisson, V.; Bruel, P.; Bruncko, D.; Brune, C.; Buchholz, R.; Büngener, L.; Bürger, J.; Büsser, F. W.; Buniatian, A.; Burke, S.; Burton, M. J.; Buschhorn, G.; Campbell, A. J.; Carli, T.; Charles, F.; Charlet, M.; Clarke, D.; Clegg, A. B.; Clerbaux, B.; Cocks, S.; Contreras, J. G.; Cormack, C.; Coughlan, J. A.; Courau, A.; Cousinou, M. C.; Cozzika, G.; Criegee, L.; Cussans, D. G.; Cvach, J.; Dagoret, S.; Dainton, J. B.; Dau, W. D.; Daum, K.; David, M.; Davis, C. L.; Delcourt, B.; de Roeck, A.; de Wolf, E. A.; Dirkmann, M.; Dixon, P.; di Nezza, P.; Dlugosz, W.; Dollfus, C.; Dowell, J. D.; Dreis, H. B.; Droutskoi, A.; Düllmann, D.; Dünger, O.; Duhm, H.; Ebert, J.; Ebert, T. R.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellison, R. J.; Elsen, E.; Erdmann, M.; Erdmann, W.; Evrard, E.; Fahr, A. B.; Favart, L.; Fedotov, A.; Feeken, D.; Felst, R.; Feltesse, J.; Ferencei, J.; Ferrarotto, F.; Flamm, K.; Fleischer, M.; Flieser, M.; Flügge, G.; Fomenko, A.; Fominykh, B.; Formánek, J.; Foster, J. M.; Franke, G.; Fretwurst, E.; Gabathuler, E.; Gabathuler, K.; Gaede, F.; Garvey, J.; Gayler, J.; Gebauer, M.; Gellrich, A.; Genzel, H.; Gerhards, R.; Glazov, A.; Goerlach, U.; Goerlich, L.; Gogitidze, N.; Goldberg, M.; Goldner, D.; Golec-Biernat, K.; Gonzalez-Pineiro, B.; Gorelov, I.; Grab, C.; Grässler, H.; Grässler, R.; Greenshaw, T.; Griffiths, R.; Grindhammer, G.; Gruber, A.; Gruber, C.; Haack, J.; Haidt, D.; Hajduk, L.; Hampel, M.; Haynes, W. J.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herynek, I.; Hess, M. F.; Hildesheim, W.; Hiller, K. H.; Hilton, C. D.; Hladky, J.; Hoeger, K. C.; Höppner, M.; Hoffmann, D.; Holtom, T.; Horisberger, R.; Hudgson, V. L.; Hütte, M.; Hufnagel, H.; Ibbotson, M.; Itterbeck, H.; Jacholkowska, A.; Jacobsson, C.; Jaffre, M.; Janoth, J.; Jansen, T.; Jönsson, L.; Johannsen, K.; Johnson, D. P.; Johnson, L.; Jung, H.; Kalmus, P. I. P.; Kander, M.; Kant, D.; Kaschowitz, R.; Kathage, U.; Katzy, J.; Kaufmann, H. H.; Kaufmann, O.; Kazarian, S.; Kenyon, I. R.; Kermiche, S.; Keuker, C.; Kiesling, C.; Klein, M.; Kleinwort, C.; Knies, G.; Köhler, T.; Köhne, J. H.; Kolanoski, H.; Kole, F.; Kolya, S. D.; Korbel, V.; Korn, M.; Kostka, P.; Kotelnikov, S. K.; Krämerkämper, T.; Krasny, M. W.; Krehbiel, H.; Krücker, D.; Krüger, U.; Krüner-Marquis, U.; Küster, H.; Kuhlen, M.; Kurča, T.; Kurzhöfer, J.; Lacour, D.; Laforge, B.; Lander, R.; Landon, M. P. J.; Lange, W.; Langenegger, U.; Laporte, J. F.; Lebedev, A.; Lehner, F.; Leverenz, C.; Levonian, S.; Ley, Ch.; Lindström, G.; Lindstroem, M.; Link, J.; Linsel, F.; Lipinski, J.; List, B.; Lobo, G.; Lohmander, H.; Lomas, J. W.; Lopez, G. C.; Lubimov, V.; Lüke, D.; Magnussen, N.; Malinovski, E.; Mani, S.; Maraček, R.; Marage, P.; Marks, J.; Marshall, R.; Martens, J.; Martin, G.; Martin, R.; Martyn, H. U.; Martyniak, J.; Mavroidis, T.; Maxfield, S. J.; McMahon, S. J.; Mehta, A.; Meier, K.; Merz, T.; Meyer, A.; Meyer, A.; Meyer, H.; Meyer, J.; Meyer, P. O.; Migliori, A.; Mikocki, S.; Milstead, D.; Moeck, J.; Moreau, F.; Morris, J. V.; Mroczko, E.; Müller, D.; Müller, G.; Müller, K.; Murín, P.; Nagovizin, V.; Nahnhauer, R.; Naroska, B.; Naumann, Th.; Newman, P. R.; Newton, D.; Neyret, D.; Nguyen, H. K.; Nicholls, T. C.; Niebergall, F.; Niebuhr, C.; Niedzballa, Ch.; Niggli, H.; Nisius, R.; Nowak, G.; Noyes, G. W.; Nyberg-Werther, M.; Oakden, M.; Oberlack, H.; Obrock, U.; Olsson, J. E.; Ozerov, D.; Palmen, P.; Panaro, E.; Panitch, A.; Pascaud, C.; Patel, G. D.; Pawletta, H.; Peppel, E.; Perez, E.; Phillips, J. P.; Pieuchot, A.; Pitzl, D.; Pope, G.; Prell, S.; Prosi, R.; Rabbertz, K.; Rädel, G.; Raupach, F.; Reimer, P.; Reinshagen, S.; Rick, H.; Riech, V.; Riedlberger, J.; Riepenhausen, F.; Riess, S.; Rizvi, E.; Robertson, S. M.; Robmann, P.; Roloff, H. E.; Roosen, R.; Rosenbauer, K.; Rostovtsev, A.; Rouse, F.; Royon, C.; Rüter, K.; Rusakov, S.; Rybicki, K.; Sahlmann, N.; Sankey, D. P. C.; Schacht, P.; Schiek, S.; Schleif, S.; Schleper, P.; von Schlippe, W.; Schmidt, D.; Schmidt, G.; Schöning, A.; Schröder, V.; Schuhmann, E.; Schwab, B.; Sefkow, F.; Seidel, M.; Sell, R.; Semenov, A.; Shekelyan, V.; Sheviakov, I.; Shtarkov, L. N.; Siegmon, G.; Siewert, U.; Sirois, Y.; Skillicorn, I. O.; Smirnov, P.; Smith, J. R.; Solochenko, V.; Soloviev, Y.; Specka, A.; Spiekermann, J.; Spielman, S.; Spitzer, H.; Squinabol, F.; Starosta, R.; Steenbock, M.; Steffen, P.; Steinberg, R.; Steiner, H.; Stella, B.; Stellberger, A.; Stier, J.; Stiewe, J.; Stößlein, U.; Stolze, K.; Straumann, U.; Struczinski, W.; Sutton, J. P.; Tapprogge, S.; Taševský, M.; Tchernyshov, V.; Tchetchelnitski, S.; Theissen, J.; Thiebaux, C.; Thompson, G.; Truöl, P.; Turnau, J.; Tutas, J.; Uelkes, P.; Usik, A.; Valkár, S.; Valkárová, A.; Vallée, C.; Vandenplas, D.; van Esch, P.; van Mechelen, P.; Vazdik, Y.; Verrecchia, P.; Villet, G.; Wacker, K.; Wagener, A.; Wagener, M.; Walther, A.; Waugh, B.; Weber, G.; Weber, M.; Wegener, D.; Wegner, A.; Wengler, T.; Werner, M.; West, L. R.; Wilksen, T.; Willard, S.; Winde, M.; Winter, G. G.; Wittek, C.; Wünsch, E.; Žáček, J.; Zarbock, D.; Zhang, Z.; Zhokin, A.; Zimmer, M.; Zomer, F.; Zsembery, J.; Zuber, K.; Zurnedden, M.

    1996-03-01

    A search for squarks of R-parity violating supersymmetry is performed in ep collisions at HERA using H1 1994 e + data. Direct single production of squarks of each generation by e +-quark fusion via a Yukawa coupling λ' is considered. All possible R-parity violating decays and gauge decays of the squarks are taken into account. No significant deviation from the Standard Model predictions is found in the various multi-lepton and multi-jet final states studied and exclusion limits are derived. At 95% confidence level, the existence of first generation squarks is excluded for masses up to 240 GeV for coupling values λ'≳√4 πα em. The limits obtained are shown to be only weakly dependent on the free parameters of the Minimal Supersymmetric Standard Model. Stop squarks are excluded for masses up to 138 GeV for coupling λ'×cos θ t to e +d pairs ≳0.1×√4 πα em, where θ t is the mass mixing angle. Light stop squarks are furthermore searched for through pair production in γ-gluon fusion processes. No signal is observed and exclusion limits are derived. Masses in the range 9 to 24.4 GeV are excluded at 95% confidence level for λ'×cos θ t>10-4.

  4. One-milliarsecond precision parallax studies in the regions of Delta Cephei and EV Lacertae

    NASA Technical Reports Server (NTRS)

    Gatewood, George; De Jonge, Kiewiet Joost; Stephenson, Bruce

    1993-01-01

    Trigonometric parallaxes for stars in the regions of the variable stars delta Cephei and EV Lacertae are derived from data collected with the Multichannel Astrometric Photometer (MAP) and the Thaw Refractor of the University of Pittsburgh's Allegheny Observatory. The weighted mean parallax of all trigonometric studies of delta Cephei is now + 0.0030 sec + or - 0.00093 sec, corresponding to a distance modulus of 7.61 + or - 0.67 mag. This indicates that this luminosity standard star is approximately one standard deviation more distance than has been generally accepted. The weighted mean trigonometric parallax of all studies of the variable star EV Lacertae (BD + 43 deg 4305) is + 0.1993 sec + or - 0.00093 sec, implying a distance modulus of - 1.498 + or - 0.0010 mag. The calculated absolute magnitude of this star is almost exactly that predicted by its (R-I)(sub Kron) magnitude and by the Gliese (R-I) main-sequence value for stars in the solar neighborhood. We also find a parallax of 0.0189 sec + or - 0.0008 sec for the FO IVn star, HR 8666 (BD + 43 sec 4300). The derived luminosity of this star is midway between that expected for luminosity class IV and V stars at the indicated temperature.

  5. Multi-scale radiomic analysis of sub-cortical regions in MRI related to autism, gender and age

    NASA Astrophysics Data System (ADS)

    Chaddad, Ahmad; Desrosiers, Christian; Toews, Matthew

    2017-03-01

    We propose using multi-scale image textures to investigate links between neuroanatomical regions and clinical variables in MRI. Texture features are derived at multiple scales of resolution based on the Laplacian-of-Gaussian (LoG) filter. Three quantifier functions (Average, Standard Deviation and Entropy) are used to summarize texture statistics within standard, automatically segmented neuroanatomical regions. Significance tests are performed to identify regional texture differences between ASD vs. TDC and male vs. female groups, as well as correlations with age (corrected p < 0.05). The open-access brain imaging data exchange (ABIDE) brain MRI dataset is used to evaluate texture features derived from 31 brain regions from 1112 subjects including 573 typically developing control (TDC, 99 females, 474 males) and 539 Autism spectrum disorder (ASD, 65 female and 474 male) subjects. Statistically significant texture differences between ASD vs. TDC groups are identified asymmetrically in the right hippocampus, left choroid-plexus and corpus callosum (CC), and symmetrically in the cerebellar white matter. Sex-related texture differences in TDC subjects are found in primarily in the left amygdala, left cerebellar white matter, and brain stem. Correlations between age and texture in TDC subjects are found in the thalamus-proper, caudate and pallidum, most exhibiting bilateral symmetry.

  6. Measuring real-time streamflow using emerging technologies: Radar, hydroacoustics, and the probability concept

    NASA Astrophysics Data System (ADS)

    Fulton, John; Ostrowski, Joseph

    2008-07-01

    SummaryForecasting streamflow during extreme hydrologic events such as floods can be problematic. This is particularly true when flow is unsteady, and river forecasts rely on models that require uniform-flow rating curves to route water from one forecast point to another. As a result, alternative methods for measuring streamflow are needed to properly route flood waves and account for inertial and pressure forces in natural channels dominated by nonuniform-flow conditions such as mild water surface slopes, backwater, tributary inflows, and reservoir operations. The objective of the demonstration was to use emerging technologies to measure instantaneous streamflow in open channels at two existing US Geological Survey streamflow-gaging stations in Pennsylvania. Surface-water and instream-point velocities were measured using hand-held radar and hydroacoustics. Streamflow was computed using the probability concept, which requires velocity data from a single vertical containing the maximum instream velocity. The percent difference in streamflow at the Susquehanna River at Bloomsburg, PA ranged from 0% to 8% with an average difference of 4% and standard deviation of 8.81 m 3/s. The percent difference in streamflow at Chartiers Creek at Carnegie, PA ranged from 0% to 11% with an average difference of 5% and standard deviation of 0.28 m 3/s. New generation equipment is being tested and developed to advance the use of radar-derived surface-water velocity and instantaneous streamflow to facilitate the collection and transmission of real-time streamflow that can be used to parameterize hydraulic routing models.

  7. Confronting Passive and Active Sensors with Non-Gaussian Statistics

    PubMed Central

    Rodríguez-Gonzálvez, Pablo.; Garcia-Gago, Jesús.; Gomez-Lahoz, Javier.; González-Aguilera, Diego.

    2014-01-01

    This paper has two motivations: firstly, to compare the Digital Surface Models (DSM) derived by passive (digital camera) and by active (terrestrial laser scanner) remote sensing systems when applied to specific architectural objects, and secondly, to test how well the Gaussian classic statistics, with its Least Squares principle, adapts to data sets where asymmetrical gross errors may appear and whether this approach should be changed for a non-parametric one. The field of geomatic technology automation is immersed in a high demanding competition in which any innovation by one of the contenders immediately challenges the opponents to propose a better improvement. Nowadays, we seem to be witnessing an improvement of terrestrial photogrammetry and its integration with computer vision to overcome the performance limitations of laser scanning methods. Through this contribution some of the issues of this “technological race” are examined from the point of view of photogrammetry. A new software is introduced and an experimental test is designed, performed and assessed to try to cast some light on this thrilling match. For the case considered in this study, the results show good agreement between both sensors, despite considerable asymmetry. This asymmetry suggests that the standard Normal parameters are not adequate to assess this type of data, especially when accuracy is of importance. In this case, standard deviation fails to provide a good estimation of the results, whereas the results obtained for the Median Absolute Deviation and for the Biweight Midvariance are more appropriate measures. PMID:25196104

  8. Measuring real-time streamflow using emerging technologies: Radar, hydroacoustics, and the probability concept

    USGS Publications Warehouse

    Fulton, J.; Ostrowski, J.

    2008-01-01

    Forecasting streamflow during extreme hydrologic events such as floods can be problematic. This is particularly true when flow is unsteady, and river forecasts rely on models that require uniform-flow rating curves to route water from one forecast point to another. As a result, alternative methods for measuring streamflow are needed to properly route flood waves and account for inertial and pressure forces in natural channels dominated by nonuniform-flow conditions such as mild water surface slopes, backwater, tributary inflows, and reservoir operations. The objective of the demonstration was to use emerging technologies to measure instantaneous streamflow in open channels at two existing US Geological Survey streamflow-gaging stations in Pennsylvania. Surface-water and instream-point velocities were measured using hand-held radar and hydroacoustics. Streamflow was computed using the probability concept, which requires velocity data from a single vertical containing the maximum instream velocity. The percent difference in streamflow at the Susquehanna River at Bloomsburg, PA ranged from 0% to 8% with an average difference of 4% and standard deviation of 8.81 m3/s. The percent difference in streamflow at Chartiers Creek at Carnegie, PA ranged from 0% to 11% with an average difference of 5% and standard deviation of 0.28 m3/s. New generation equipment is being tested and developed to advance the use of radar-derived surface-water velocity and instantaneous streamflow to facilitate the collection and transmission of real-time streamflow that can be used to parameterize hydraulic routing models.

  9. Space imaging measurement system based on fixed lens and moving detector

    NASA Astrophysics Data System (ADS)

    Akiyama, Akira; Doshida, Minoru; Mutoh, Eiichiro; Kumagai, Hideo; Yamada, Hirofumi; Ishii, Hiromitsu

    2006-08-01

    We have developed the Space Imaging Measurement System based on the fixed lens and fast moving detector to the control of the autonomous ground vehicle. The space measurement is the most important task in the development of the autonomous ground vehicle. In this study we move the detector back and forth along the optical axis at the fast rate to measure the three-dimensional image data. This system is just appropriate to the autonomous ground vehicle because this system does not send out any optical energy to measure the distance and keep the safety. And we use the digital camera of the visible ray range. Therefore it gives us the cost reduction of the three-dimensional image data acquisition with respect to the imaging laser system. We can combine many pieces of the narrow space imaging measurement data to construct the wide range three-dimensional data. This gives us the improvement of the image recognition with respect to the object space. To develop the fast movement of the detector, we build the counter mass balance in the mechanical crank system of the Space Imaging Measurement System. And then we set up the duct to prevent the optical noise due to the ray not coming through lens. The object distance is derived from the focus distance which related to the best focused image data. The best focused image data is selected from the image of the maximum standard deviation in the standard deviations of series images.

  10. Design, implementation and accuracy of a prototype for medical augmented reality.

    PubMed

    Pandya, Abhilash; Siadat, Mohammad-Reza; Auner, Greg

    2005-01-01

    This paper is focused on prototype development and accuracy evaluation of a medical Augmented Reality (AR) system. The accuracy of such a system is of critical importance for medical use, and is hence considered in detail. We analyze the individual error contributions and the system accuracy of the prototype. A passive articulated arm is used to track a calibrated end-effector-mounted video camera. The live video view is superimposed in real time with the synchronized graphical view of CT-derived segmented object(s) of interest within a phantom skull. The AR accuracy mostly depends on the accuracy of the tracking technology, the registration procedure, the camera calibration, and the image scanning device (e.g., a CT or MRI scanner). The accuracy of the Microscribe arm was measured to be 0.87 mm. After mounting the camera on the tracking device, the AR accuracy was measured to be 2.74 mm on average (standard deviation = 0.81 mm). After using data from a 2-mm-thick CT scan, the AR error remained essentially the same at an average of 2.75 mm (standard deviation = 1.19 mm). For neurosurgery, the acceptable error is approximately 2-3 mm, and our prototype approaches these accuracy requirements. The accuracy could be increased with a higher-fidelity tracking system and improved calibration and object registration. The design and methods of this prototype device can be extrapolated to current medical robotics (due to the kinematic similarity) and neuronavigation systems.

  11. [Study on freshness evaluation of ice-stored large yellow croaker (Pseudosciaena crocea) using near infrared spectroscopy].

    PubMed

    Liu, Yuan; Chen, Wei-Hua; Hou, Qiao-Juan; Wang, Xi-Chang; Dong, Ruo-Yan; Wu, Hao

    2014-04-01

    Near infrared spectroscopy (NIR) was used in this experiment to evaluate the freshness of ice-stored large yellow croaker (Pseudosciaena crocea) during different storage periods. And the TVB-N was used as an index to evaluate the freshness. Through comparing the correlation coefficent and standard deviations of calibration set and validation set of models established by singly and combined using of different pretreatment methods, different modeling methods and different wavelength region, the best TVB-N models of ice-stored large yellow croaker sold in the market were established to predict the freshness quickly. According to the research, the model shows that the best performance could be established by using the normalization by closure (Ncl) with 1st derivative (Dbl) and normalization to unit length (Nle) with 1st derivative as the pretreated method and partial least square (PLS) as the modeling method combined with choosing the wavelength region of 5 000-7 144, and 7 404-10 000 cm(-1). The calibration model gave the correlation coefficient of 0.992, with a standard error of calibration of 1.045 and the validation model gave the correlation coefficient of 0.999, with a standard error of prediction of 0.990. This experiment attempted to combine several pretreatment methods and choose the best wavelength region, which has got a good result. It could have a good prospective application of freshness detection and quality evaluation of large yellow croaker in the market.

  12. Target-depth estimation in active sonar: Cramer-Rao bounds for a bilinear sound-speed profile.

    PubMed

    Mours, Alexis; Ioana, Cornel; Mars, Jérôme I; Josso, Nicolas F; Doisy, Yves

    2016-09-01

    This paper develops a localization method to estimate the depth of a target in the context of active sonar, at long ranges. The target depth is tactical information for both strategy and classification purposes. The Cramer-Rao lower bounds for the target position as range and depth are derived for a bilinear profile. The influence of sonar parameters on the standard deviations of the target range and depth are studied. A localization method based on ray back-propagation with a probabilistic approach is then investigated. Monte-Carlo simulations applied to a summer Mediterranean sound-speed profile are performed to evaluate the efficiency of the estimator. This method is finally validated on data in an experimental tank.

  13. Analysis of variances of quasirapidities in collisions of gold nuclei with track-emulsion nuclei

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gulamov, K. G.; Zhokhova, S. I.; Lugovoi, V. V., E-mail: lugovoi@uzsci.net

    2012-08-15

    A new method of an analysis of variances was developed for studying n-particle correlations of quasirapidities in nucleus-nucleus collisions for a large constant number n of particles. Formulas that generalize the results of the respective analysis to various values of n were derived. Calculations on the basis of simple models indicate that the method is applicable, at least for n {>=} 100. Quasirapidity correlations statistically significant at a level of 36 standard deviations were discovered in collisions between gold nuclei and track-emulsion nuclei at an energy of 10.6 GeV per nucleon. The experimental data obtained in our present study aremore » contrasted against the theory of nucleus-nucleus collisions.« less

  14. Detailed gravity anomalies from GEOS-3 satellite altimetry data

    NASA Technical Reports Server (NTRS)

    Gopalapillai, G. S.; Mourad, A. G.

    1978-01-01

    A technique for deriving mean gravity anomalies from dense altimetry data was developed. A combination of both deterministic and statistical techniques was used. The basic mathematical model was based on the Stokes' equation which describes the analytical relationship between mean gravity anomalies and geoid undulations at a point; this undulation is a linear function of the altimetry data at that point. The overdetermined problem resulting from the excessive altimetry data available was solved using Least-Squares principles. These principles enable the simultaneous estimation of the associated standard deviations reflecting the internal consistency based on the accuracy estimates provided for the altimetry data as well as for the terrestrial anomaly data. Several test computations were made of the anomalies and their accuracy estimates using GOES-3 data.

  15. Observation of Pure Rotational Spectra of SiCCN by Fourier-Transform Microwave Spectroscopy

    NASA Astrophysics Data System (ADS)

    Umeki, Hiroya; Nakajima, Masakazu; Endo, Yasuki

    2014-06-01

    Pure rotational spectra of SiCCN ( ˜{X} 2Π3/2) have been observed using Fourier-transform microwave (FTMW) spectroscopy in the frequency region 13 to 35 GHz. The SiCCN radical was produced in a supersonic jet by discharging a mixture gas, 0.2% SiCl4 and 0.2% CH3CN diluted in Ar. The effective rotational constant Beff,3/2, the centrifugal distortion constant D, and the hyperfine coupling constants, a + (b + c)/2 and eQq0, were determined with a standard deviation of the fit to be 6 kHz. Determined B and eQq0 are consistent with those derived from ab initio calculations. Λ-type doublings were not resolved for the observed spectra.

  16. Microwave dielectric study of polar liquids at 298 K

    NASA Astrophysics Data System (ADS)

    Maharolkar, Aruna P.; Murugkar, A.; Khirade, P. W.

    2018-05-01

    Present paper deals with study of microwave dielectric properties like dielectric constant, viscosity, density and refractive index for the binary mixtures of Dimethylsulphoxide (DMSO) and Methanol over the entire concentration range were measured at 298K. The experimental data further used to determine the excess properties viz. excess static dielectric constant, excess molar volume, excess viscosity& derived properties viz. molar refraction&Bruggman factor. The values of excess properties further fitted with Redlich-Kister (R-K Fit) equation to calculate the binary coefficients and standard deviation. The resulting excess parameters are used to indicate the presence of intermolecular interactions and strength of intermolecular interactions between the molecules in the binary mixtures. Excess parameters indicate structure breaking factor in the mixture predominates in the system.

  17. High-Resolution FTIR Spectrum of the ν 12 Band of trans- d2-Ethylene

    NASA Astrophysics Data System (ADS)

    Teo, H. H.; Ong, P. P.; Tan, T. L.; Goh, K. L.

    2000-11-01

    The ν12 band of trans-d2-ethylene (trans-C2H2D2) has been recorded with an unapodized resolution of 0.0024 cm-1 in the frequency range of 1240-1360 cm-1 by Fourier transform infrared (FTIR) spectroscopy. This band was found to be relatively free from any local frequency perturbations. By fitting a total of 1185 infrared transitions of ν12 with a standard deviation of 0.00043 cm-1 using a Watson's A-reduced Hamiltonian in the Ir representation, a set of accurate rovibrational constants for v12 = 1 state was derived. The ν12 band is A type with a band center at 1298.03797 ± 0.00004 cm-1.

  18. On the Effect of Energy Conservation on Black Hole Evaporation

    NASA Astrophysics Data System (ADS)

    Torres, R.; Fayos, F.; Lorente-Espín, O.

    2013-06-01

    We consider the emission of Hawking radiation by black holes as a consequence of a tunneling process. By requiring energy conservation in the derivation of the emission rate we get a well-known deviation from an exact thermal spectrum. A model that takes into account the implications of energy conservation, as well as the back-scattered radiation, is then constructed in order to describe the evolution of black holes as they evaporate. The evaporation process in this model is compared with the results in the standard "thermal" approximation. This allows us to point out the relevance that energy conservation might have in the last stages of black hole evaporation. We also comment about the possible implications of energy conservation in the information loss paradox.

  19. Streamflow statistical summaries for Colorado streams through September 30, 1975: Volume 1: Missouri River, Arkansas River, and Rio Grande Basins

    USGS Publications Warehouse

    Petsch, Harold E.

    1979-01-01

    Statistical summaries of daily streamflow data for 246 stations east of the Continental Divide in Colorado and adjacent States are presented in this report. Duration tables, high-flow sequence tables, and low-flow sequence tables provide information about daily mean discharge. The mean, variance, standard deviation, skewness, and coefficient of variation are provided for monthly and annual flows. Percentages of average flow are provided for monthly flows and first-order serial-correlation coefficients are provided for annual flows. The text explains the nature and derivation of the data and illustrates applications of the tabulated information by examples. The data may be used by agencies and individuals engaged in water studies. (USGS)

  20. Large-deviation properties of Brownian motion with dry friction.

    PubMed

    Chen, Yaming; Just, Wolfram

    2014-10-01

    We investigate piecewise-linear stochastic models with regard to the probability distribution of functionals of the stochastic processes, a question that occurs frequently in large deviation theory. The functionals that we are looking into in detail are related to the time a stochastic process spends at a phase space point or in a phase space region, as well as to the motion with inertia. For a Langevin equation with discontinuous drift, we extend the so-called backward Fokker-Planck technique for non-negative support functionals to arbitrary support functionals, to derive explicit expressions for the moments of the functional. Explicit solutions for the moments and for the distribution of the so-called local time, the occupation time, and the displacement are derived for the Brownian motion with dry friction, including quantitative measures to characterize deviation from Gaussian behavior in the asymptotic long time limit.

  1. Effects of aortic tortuosity on left ventricular diastolic parameters derived from gated myocardial perfusion single photon emission computed tomography in patients with normal myocardial perfusion.

    PubMed

    Kurisu, Satoshi; Nitta, Kazuhiro; Sumimoto, Yoji; Ikenaga, Hiroki; Ishibashi, Ken; Fukuda, Yukihiro; Kihara, Yasuki

    2018-06-01

    Aortic tortuosity is often found on chest radiograph, especially in aged patients. We tested the hypothesis that aortic tortuosity was associated with LV diastolic parameters derived from gated SPECT in patients with normal myocardial perfusion. One-hundred and twenty-two patients with preserved LV ejection fraction and normal myocardial perfusion were enrolled. Descending aortic deviation was defined as the horizontal distance from the left line of the aortic knob to the most prominent left line of the descending aorta. This parameter was measured for the quantitative assessment of aortic tortuosity. Peak filling rate (PFR) and one-third mean filling rate (1/3 MFR) were obtained from redistribution images as LV diastolic parameters. Descending aortic deviation ranged from 0 to 22 mm with a mean distance of 4.5 ± 6.3 mm. Descending aortic deviation was significantly correlated with age (r = 0.38, p < 0.001) and estimated glomerular filtration rate (eGFR) (r = - 0.21, p = 0.02). Multivariate linear regression analysis revealed that eGFR (β = 0.23, p = 0.02) and descending aortic deviation (β = - 0.23, p = 0.01) were significantly associated with PFR, and that only descending aortic deviation (β = - 0.21, p = 0.03) was significantly associated with 1/3 MFR. Our data suggest that aortic tortuosity is associated with LV diastolic parameters derived from gated SPECT in patients with normal myocardial perfusion.

  2. Determining the Equation of State (EoS) Parameters for Ballistic Gelatin

    DTIC Science & Technology

    2015-09-01

    standard deviation. The specific heat measured at room temperature reported in (Winter 1975) is approximately 1.13 cal/g/°C (= 4.73 J /g/K). Fig. 4...Piatt 2010) Table 3 Specific heat capacity, average heat capacity, and standard deviation Temperature (°C) Cp [ J /(g·K)] Cp Cp Cp Average Cp...density amorphous ice and their implications on pressure induced amorphization. J Chem Physics. 2005;122:124710. Appleby-Thomas GJ, Hazell PJ

  3. Precision Geolocation of Active Electromagnetic Sensors Using Stationary Magnetic Sensors

    DTIC Science & Technology

    2009-09-01

    0.0003, 0.0003 ] m TiltMeter Mean Pitch: -1.71576990 and Roll: 0.92591697 LSQ Moment Pitch: 0.00576850 and Roll: -0.35543026 Run #5...Standard deviation of optimized solution: [ 0.0028, 0.0014, 0.0012 ] m TiltMeter Mean Pitch: -1.08757549 and Roll: 1.09065730 LSQ Moment...0.00, 0.00, -434.95 ] Standard deviation of optimized solution: [ 0.0051, 0.0031, 0.0035 ] m TiltMeter Mean Pitch: 0.05301905

  4. Coherent and Semiclassical States of a Charged Particle in a Constant Electric Field

    NASA Astrophysics Data System (ADS)

    Adorno, T. C.; Pereira, A. S.

    2018-05-01

    The method of integrals of motion is used to construct families of generalized coherent states of a nonrelativistic spinless charged particle in a constant electric field. Families of states, differing in the values of their standard deviations at the initial time, are obtained. Depending on the initial values of the standard deviations, and also on the electric field, it turns out to be possible to identify some families with semiclassical states.

  5. Statistical characteristics of cloud variability. Part 1: Retrieved cloud liquid water path at three ARM sites

    NASA Astrophysics Data System (ADS)

    Huang, Dong; Campos, Edwin; Liu, Yangang

    2014-09-01

    Statistical characteristics of cloud variability are examined for their dependence on averaging scales and best representation of probability density function with the decade-long retrieval products of cloud liquid water path (LWP) from the tropical western Pacific (TWP), Southern Great Plains (SGP), and North Slope of Alaska (NSA) sites of the Department of Energy's Atmospheric Radiation Measurement Program. The statistical moments of LWP show some seasonal variation at the SGP and NSA sites but not much at the TWP site. It is found that the standard deviation, relative dispersion (the ratio of the standard deviation to the mean), and skewness all quickly increase with the averaging window size when the window size is small and become more or less flat when the window size exceeds 12 h. On average, the cloud LWP at the TWP site has the largest values of standard deviation, relative dispersion, and skewness, whereas the NSA site exhibits the least. Correlation analysis shows that there is a positive correlation between the mean LWP and the standard deviation. The skewness is found to be closely related to the relative dispersion with a correlation coefficient of 0.6. The comparison further shows that the lognormal, Weibull, and gamma distributions reasonably explain the observed relationship between skewness and relative dispersion over a wide range of scales.

  6. Statistical characteristics of cloud variability. Part 1: Retrieved cloud liquid water path at three ARM sites: Observed cloud variability at ARM sites

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Dong; Campos, Edwin; Liu, Yangang

    2014-09-17

    Statistical characteristics of cloud variability are examined for their dependence on averaging scales and best representation of probability density function with the decade-long retrieval products of cloud liquid water path (LWP) from the tropical western Pacific (TWP), Southern Great Plains (SGP), and North Slope of Alaska (NSA) sites of the Department of Energy’s Atmospheric Radiation Measurement Program. The statistical moments of LWP show some seasonal variation at the SGP and NSA sites but not much at the TWP site. It is found that the standard deviation, relative dispersion (the ratio of the standard deviation to the mean), and skewness allmore » quickly increase with the averaging window size when the window size is small and become more or less flat when the window size exceeds 12 h. On average, the cloud LWP at the TWP site has the largest values of standard deviation, relative dispersion, and skewness, whereas the NSA site exhibits the least. Correlation analysis shows that there is a positive correlation between the mean LWP and the standard deviation. The skewness is found to be closely related to the relative dispersion with a correlation coefficient of 0.6. The comparison further shows that the log normal, Weibull, and gamma distributions reasonably explain the observed relationship between skewness and relative dispersion over a wide range of scales.« less

  7. Measurements of leakage from Lake Michigan through three control structures near Chicago, Illinois, April-October 1993

    USGS Publications Warehouse

    Oberg, K.A.; Schmidt, A.R.

    1994-01-01

    A total of 213 measurements of leakage were made at three control structures near Chicago, Ill.--the Chicago River Controlling Works (CRCW), Thomas J. O'Brien Lock and Dam (O'Brien), and Wilmette Pumping Station (Wilmette)--using acoustic Doppler current profilers (ADCP's) and dye-dilution techniques. The CRCW consists of the Chicago Lock and two sets of sluice gates connected by a network of harbor walls. Leakage measurements were made in April, May, July, September, and October 1993 using an ADCP. The mean and standard deviation of leakage measured by the ADCP for the Chicago Lock river gate were 133 and 39 cubic feet per second, respectively. The mean and standard deviation of the leakage measurements at CRCW were 204 and 70 cubic feet per second, respectively. The mean and standard deviation of leakage measurements at O'Brien on September 17, 1993, were 21 and 10 cubic feet per second, respectively. The mean and standard deviation leakage measured at Wilmette using the ADCP were 59 and 8 cubic feet per second, respectively, in April 1993. After the pump bays at Wilmette were sealed in July 1993, the leakage dropped to less than 15 cubic feet per second in September 1993. Discharge estimated by dye-dilution at the Chicago Lock on July 15, 1993, was 160 cubic feet per second, or within 8 percent of the discharge measured with the ADCP. (USGS)

  8. Hazardous Traffic Event Detection Using Markov Blanket and Sequential Minimal Optimization (MB-SMO)

    PubMed Central

    Yan, Lixin; Zhang, Yishi; He, Yi; Gao, Song; Zhu, Dunyao; Ran, Bin; Wu, Qing

    2016-01-01

    The ability to identify hazardous traffic events is already considered as one of the most effective solutions for reducing the occurrence of crashes. Only certain particular hazardous traffic events have been studied in previous studies, which were mainly based on dedicated video stream data and GPS data. The objective of this study is twofold: (1) the Markov blanket (MB) algorithm is employed to extract the main factors associated with hazardous traffic events; (2) a model is developed to identify hazardous traffic event using driving characteristics, vehicle trajectory, and vehicle position data. Twenty-two licensed drivers were recruited to carry out a natural driving experiment in Wuhan, China, and multi-sensor information data were collected for different types of traffic events. The results indicated that a vehicle’s speed, the standard deviation of speed, the standard deviation of skin conductance, the standard deviation of brake pressure, turn signal, the acceleration of steering, the standard deviation of acceleration, and the acceleration in Z (G) have significant influences on hazardous traffic events. The sequential minimal optimization (SMO) algorithm was adopted to build the identification model, and the accuracy of prediction was higher than 86%. Moreover, compared with other detection algorithms, the MB-SMO algorithm was ranked best in terms of the prediction accuracy. The conclusions can provide reference evidence for the development of dangerous situation warning products and the design of intelligent vehicles. PMID:27420073

  9. Sickle cell disease diagnosis based on spatio-temporal cell dynamics analysis using 3D printed shearing digital holographic microscopy.

    PubMed

    Javidi, Bahram; Markman, Adam; Rawat, Siddharth; O'Connor, Timothy; Anand, Arun; Andemariam, Biree

    2018-05-14

    We present a spatio-temporal analysis of cell membrane fluctuations to distinguish healthy patients from patients with sickle cell disease. A video hologram containing either healthy red blood cells (h-RBCs) or sickle cell disease red blood cells (SCD-RBCs) was recorded using a low-cost, compact, 3D printed shearing interferometer. Reconstructions were created for each hologram frame (time steps), forming a spatio-temporal data cube. Features were extracted by computing the standard deviations and the mean of the height fluctuations over time and for every location on the cell membrane, resulting in two-dimensional standard deviation and mean maps, followed by taking the standard deviations of these maps. The optical flow algorithm was used to estimate the apparent motion fields between subsequent frames (reconstructions). The standard deviation of the magnitude of the optical flow vectors across all frames was then computed. In addition, seven morphological cell (spatial) features based on optical path length were extracted from the cells to further improve the classification accuracy. A random forest classifier was trained to perform cell identification to distinguish between SCD-RBCs and h-RBCs. To the best of our knowledge, this is the first report of machine learning assisted cell identification and diagnosis of sickle cell disease based on cell membrane fluctuations and morphology using both spatio-temporal and spatial analysis.

  10. Reductions in the variations of respiration signals for respiratory-gated radiotherapy when using the video-coaching respiration guiding system

    NASA Astrophysics Data System (ADS)

    Lee, Hyun Jeong; Yea, Ji Woon; Oh, Se An

    2015-07-01

    Respiratory-gated radiation therapy (RGRT) has been used to minimize the dose to normal tissue in lung-cancer radiotherapy. The present research aims to improve the regularity of respiration in RGRT by using a video-coached respiration guiding system. In the study, 16 patients with lung cancer were evaluated. The respiration signals of the patients were measured by using a realtime position management (RPM) respiratory gating system (Varian, USA), and the patients were trained using the video-coaching respiration guiding system. The patients performed free breathing and guided breathing, and the respiratory cycles were acquired for ~5 min. Then, Microsoft Excel 2010 software was used to calculate the mean and the standard deviation for each phase. The standard deviation was computed in order to analyze the improvement in the respiratory regularity with respect to the period and the displacement. The standard deviation of the guided breathing decreased to 48.8% in the inhale peak and 24.2% in the exhale peak compared with the values for the free breathing of patient 6. The standard deviation of the respiratory cycle was found to be decreased when using the respiratory guiding system. The respiratory regularity was significantly improved when using the video-coaching respiration guiding system. Therefore, the system is useful for improving the accuracy and the efficiency of RGRT.

  11. Hazardous Traffic Event Detection Using Markov Blanket and Sequential Minimal Optimization (MB-SMO).

    PubMed

    Yan, Lixin; Zhang, Yishi; He, Yi; Gao, Song; Zhu, Dunyao; Ran, Bin; Wu, Qing

    2016-07-13

    The ability to identify hazardous traffic events is already considered as one of the most effective solutions for reducing the occurrence of crashes. Only certain particular hazardous traffic events have been studied in previous studies, which were mainly based on dedicated video stream data and GPS data. The objective of this study is twofold: (1) the Markov blanket (MB) algorithm is employed to extract the main factors associated with hazardous traffic events; (2) a model is developed to identify hazardous traffic event using driving characteristics, vehicle trajectory, and vehicle position data. Twenty-two licensed drivers were recruited to carry out a natural driving experiment in Wuhan, China, and multi-sensor information data were collected for different types of traffic events. The results indicated that a vehicle's speed, the standard deviation of speed, the standard deviation of skin conductance, the standard deviation of brake pressure, turn signal, the acceleration of steering, the standard deviation of acceleration, and the acceleration in Z (G) have significant influences on hazardous traffic events. The sequential minimal optimization (SMO) algorithm was adopted to build the identification model, and the accuracy of prediction was higher than 86%. Moreover, compared with other detection algorithms, the MB-SMO algorithm was ranked best in terms of the prediction accuracy. The conclusions can provide reference evidence for the development of dangerous situation warning products and the design of intelligent vehicles.

  12. [Study of building quantitative analysis model for chlorophyll in winter wheat with reflective spectrum using MSC-ANN algorithm].

    PubMed

    Liang, Xue; Ji, Hai-yan; Wang, Peng-xin; Rao, Zhen-hong; Shen, Bing-hui

    2010-01-01

    Preprocess method of multiplicative scatter correction (MSC) was used to reject noises in the original spectra produced by the environmental physical factor effectively, then the principal components of near-infrared spectroscopy were calculated by nonlinear iterative partial least squares (NIPALS) before building the back propagation artificial neural networks method (BP-ANN), and the numbers of principal components were calculated by the method of cross validation. The calculated principal components were used as the inputs of the artificial neural networks model, and the artificial neural networks model was used to find the relation between chlorophyll in winter wheat and reflective spectrum, which can predict the content of chlorophyll in winter wheat. The correlation coefficient (r) of calibration set was 0.9604, while the standard deviation (SD) and relative standard deviation (RSD) was 0.187 and 5.18% respectively. The correlation coefficient (r) of predicted set was 0.9600, and the standard deviation (SD) and relative standard deviation (RSD) was 0.145 and 4.21% respectively. It means that the MSC-ANN algorithm can reject noises in the original spectra produced by the environmental physical factor effectively and set up an exact model to predict the contents of chlorophyll in living leaves veraciously to replace the classical method and meet the needs of fast analysis of agricultural products.

  13. Professionalism in medical students at a private medical college in Karachi, Pakistan.

    PubMed

    Sobani, Zain-ul-abedeen; Mohyuddin, Muhammad Masaud; Farooq, Fahd; Qaiser, Kanza Noor; Gani, Faiz; Bham, Nida Shahab; Raheem, Ahmed; Mehraj, Vikram; Saeed, Syed Abdul; Sharif, Hasanat; Sheerani, Mughis; Zuberi, Rukhsana Wamiq; Beg, Mohamamd Asim

    2013-07-01

    To determine levels of professionalism in undergraduate medical students at a private medical college and assess how changes emerge during their training. The study was conducted at Aga Khan University, a tertiary care teaching hospital, during November and December 2011. Freshmen, Year 3 and Year 5 students were requested to fill out a questionnaire. It was designed to assess the participants' levels of professionalism and how they perceived the professional environment around them by incorporating previously described scales. The questionnaire was re-validated on a random sample of practising clinicians at the same hospital. SPSS 17 was used for statistical analysis. The study sample comprised 204 participants. The mean score for level of individual professionalism was 7.72+/-3.43. Only 13 (6.4%) students had a score one standard deviation above the faculty mean. About 24 (11.8%) were one standard deviation and 35 (17.2%) were 2 standard deviations below the faculty mean. The remaining 130 (63.7%) were >2 standard deviations below the faculty mean. Considering the level of education, the mean score for level of professionalism was 8.00+/-3.39 for freshmen, 6.85+/-3.41 for year 3 students, and 8.40+/-3.34 for year 5 students. The currently employed teaching practices inculcating the values of professionalism in medical students are serving as a buffer to maintain the pre-training levels of professionalism from declining.

  14. Longitudinal meta-analysis of NIST pH Standard Reference Materials(®): a complement to pH key comparisons.

    PubMed

    Pratt, Kenneth W

    2015-04-01

    This meta-analysis assesses the long-term (up to 70 years) within-laboratory variation of the NIST pH Standard Reference Material® (SRM) tetroxalate, phthalate, phosphate, borate, and carbonate buffers. Values of ΔpH(S), the difference between the certified pH value, pH(S), of each SRM issue and the mean of all pH(S) values for the given SRM at that Celsius temperature, t, are graphed as a function of the SRM issue and t. In most cases, |ΔpH(S)| < 0.004. Deviations from the nominal base:acid amount (mole) ratio of a buffer yield t-independent, constant shifts in ΔpH(S). The mean ΔpH(S) characterizes such deviations. The corresponding mole fraction of impurity in the conjugate buffer component is generally <0.3 %. Changes in the equipment, personnel, materials, and methodology of the pH(S) measurement yield t-dependent variations. The standard deviation of ΔpH(S) characterizes such changes. Standard deviations of ΔpH(S) are generally 0.0015 or less. The results provide a long-term, single-institution complement to the time-specific, multi-institution results of pH key comparisons administered by the Consultative Committee for Metrology in Chemistry and Biology (CCQM).

  15. Conventional multi-slice computed tomography (CT) and cone-beam CT (CBCT) for computer-aided implant placement. Part II: reliability of mucosa-supported stereolithographic guides.

    PubMed

    Arisan, Volkan; Karabuda, Zihni Cüneyt; Pişkin, Bülent; Özdemir, Tayfun

    2013-12-01

    Deviations of implants that were placed by conventional computed tomography (CT)- or cone beam CT (CBCT)-derived mucosa-supported stereolithographic (SLA) surgical guides were analyzed in this study. Eleven patients were randomly scanned by a multi-slice CT (CT group) or a CBCT scanner (CBCT group). A total of 108 implants were planned on the software and placed using SLA guides. A new CT or CBCT scan was obtained and merged with the planning data to identify the deviations between the planned and placed implants. Results were analyzed by Mann-Whitney U test and multiple regressions (p < .05). Mean angular and linear deviations in the CT group were 3.30° (SD 0.36), and 0.75 (SD 0.32) and 0.80 mm (SD 0.35) at the implant shoulder and tip, respectively. In the CBCT group, mean angular and linear deviations were 3.47° (SD 0.37), and 0.81 (SD 0.32) and 0.87 mm (SD 0.32) at the implant shoulder and tip, respectively. No statistically significant differences were detected between the CT and CBCT groups (p = .169 and p = .551, p = .113 for angular and linear deviations, respectively). Implant placement via CT- or CBCT-derived mucosa-supported SLA guides yielded similar deviation values. Results should be confirmed on alternative CBCT scanners. © 2012 Wiley Periodicals, Inc.

  16. Measurement of global functional performance in patients with rheumatoid arthritis using rheumatology function tests

    PubMed Central

    Escalante, Agustín; Haas, Roy W; del Rincón, Inmaculada

    2004-01-01

    Outcome assessment in patients with rheumatoid arthritis (RA) includes measurement of physical function. We derived a scale to quantify global physical function in RA, using three performance-based rheumatology function tests (RFTs). We measured grip strength, walking velocity, and shirt button speed in consecutive RA patients attending scheduled appointments at six rheumatology clinics, repeating these measurements after a median interval of 1 year. We extracted the underlying latent variable using principal component factor analysis. We used the Bayesian information criterion to assess the global physical function scale's cross-sectional fit to criterion standards. The criteria were joint tenderness, swelling, and deformity, pain, physical disability, current work status, and vital status at 6 years after study enrolment. We computed Guyatt's responsiveness statistic for improvement according to the American College of Rheumatology (ACR) definition. Baseline functional performance data were available for 777 patients, and follow-up data were available for 681. Mean ± standard deviation for each RFT at baseline were: grip strength, 14 ± 10 kg; walking velocity, 194 ± 82 ft/min; and shirt button speed, 7.1 ± 3.8 buttons/min. Grip strength and walking velocity departed significantly from normality. The three RFTs loaded strongly on a single factor that explained ≥70% of their combined variance. We rescaled the factor to vary from 0 to 100. Its mean ± standard deviation was 41 ± 20, with a normal distribution. The new global scale had a stronger fit than the primary RFT to most of the criterion standards. It correlated more strongly with physical disability at follow-up and was more responsive to improvement defined according to the ACR20 and ACR50 definitions. We conclude that a performance-based physical function scale extracted from three RFTs has acceptable distributional and measurement properties and is responsive to clinically meaningful change. It provides a parsimonious scale to measure global physical function in RA. PMID:15225367

  17. Quantifying the impact of sub-grid surface wind variability on sea salt and dust emissions in CAM5

    NASA Astrophysics Data System (ADS)

    Zhang, Kai; Zhao, Chun; Wan, Hui; Qian, Yun; Easter, Richard C.; Ghan, Steven J.; Sakaguchi, Koichi; Liu, Xiaohong

    2016-02-01

    This paper evaluates the impact of sub-grid variability of surface wind on sea salt and dust emissions in the Community Atmosphere Model version 5 (CAM5). The basic strategy is to calculate emission fluxes multiple times, using different wind speed samples of a Weibull probability distribution derived from model-predicted grid-box mean quantities. In order to derive the Weibull distribution, the sub-grid standard deviation of surface wind speed is estimated by taking into account four mechanisms: turbulence under neutral and stable conditions, dry convective eddies, moist convective eddies over the ocean, and air motions induced by mesoscale systems and fine-scale topography over land. The contributions of turbulence and dry convective eddy are parameterized using schemes from the literature. Wind variabilities caused by moist convective eddies and fine-scale topography are estimated using empirical relationships derived from an operational weather analysis data set at 15 km resolution. The estimated sub-grid standard deviations of surface wind speed agree well with reference results derived from 1 year of global weather analysis at 15 km resolution and from two regional model simulations with 3 km grid spacing.The wind-distribution-based emission calculations are implemented in CAM5. In terms of computational cost, the increase in total simulation time turns out to be less than 3 %. Simulations at 2° resolution indicate that sub-grid wind variability has relatively small impacts (about 7 % increase) on the global annual mean emission of sea salt aerosols, but considerable influence on the emission of dust. Among the considered mechanisms, dry convective eddies and mesoscale flows associated with topography are major causes of dust emission enhancement. With all the four mechanisms included and without additional adjustment of uncertain parameters in the model, the simulated global and annual mean dust emission increase by about 50 % compared to the default model. By tuning the globally constant dust emission scale factor, the global annual mean dust emission, aerosol optical depth, and top-of-atmosphere radiative fluxes can be adjusted to the level of the default model, but the frequency distribution of dust emission changes, with more contribution from weaker wind events and less contribution from stronger wind events. In Africa and Asia, the overall frequencies of occurrence of dust emissions increase, and the seasonal variations are enhanced, while the geographical patterns of the emission frequency show little change.

  18. Quantifying the impact of sub-grid surface wind variability on sea salt and dust emissions in CAM5

    DOE PAGES

    Zhang, Kai; Zhao, Chun; Wan, Hui; ...

    2016-02-12

    This paper evaluates the impact of sub-grid variability of surface wind on sea salt and dust emissions in the Community Atmosphere Model version 5 (CAM5). The basic strategy is to calculate emission fluxes multiple times, using different wind speed samples of a Weibull probability distribution derived from model-predicted grid-box mean quantities. In order to derive the Weibull distribution, the sub-grid standard deviation of surface wind speed is estimated by taking into account four mechanisms: turbulence under neutral and stable conditions, dry convective eddies, moist convective eddies over the ocean, and air motions induced by mesoscale systems and fine-scale topography overmore » land. The contributions of turbulence and dry convective eddy are parameterized using schemes from the literature. Wind variabilities caused by moist convective eddies and fine-scale topography are estimated using empirical relationships derived from an operational weather analysis data set at 15 km resolution. The estimated sub-grid standard deviations of surface wind speed agree well with reference results derived from 1 year of global weather analysis at 15 km resolution and from two regional model simulations with 3 km grid spacing.The wind-distribution-based emission calculations are implemented in CAM5. In terms of computational cost, the increase in total simulation time turns out to be less than 3 %. Simulations at 2° resolution indicate that sub-grid wind variability has relatively small impacts (about 7 % increase) on the global annual mean emission of sea salt aerosols, but considerable influence on the emission of dust. Among the considered mechanisms, dry convective eddies and mesoscale flows associated with topography are major causes of dust emission enhancement. With all the four mechanisms included and without additional adjustment of uncertain parameters in the model, the simulated global and annual mean dust emission increase by about 50 % compared to the default model. By tuning the globally constant dust emission scale factor, the global annual mean dust emission, aerosol optical depth, and top-of-atmosphere radiative fluxes can be adjusted to the level of the default model, but the frequency distribution of dust emission changes, with more contribution from weaker wind events and less contribution from stronger wind events. Lastly, in Africa and Asia, the overall frequencies of occurrence of dust emissions increase, and the seasonal variations are enhanced, while the geographical patterns of the emission frequency show little change.« less

  19. Quantifying the impact of sub-grid surface wind variability on sea salt and dust emissions in CAM5

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Kai; Zhao, Chun; Wan, Hui

    This paper evaluates the impact of sub-grid variability of surface wind on sea salt and dust emissions in the Community Atmosphere Model version 5 (CAM5). The basic strategy is to calculate emission fluxes multiple times, using different wind speed samples of a Weibull probability distribution derived from model-predicted grid-box mean quantities. In order to derive the Weibull distribution, the sub-grid standard deviation of surface wind speed is estimated by taking into account four mechanisms: turbulence under neutral and stable conditions, dry convective eddies, moist convective eddies over the ocean, and air motions induced by mesoscale systems and fine-scale topography overmore » land. The contributions of turbulence and dry convective eddy are parameterized using schemes from the literature. Wind variabilities caused by moist convective eddies and fine-scale topography are estimated using empirical relationships derived from an operational weather analysis data set at 15 km resolution. The estimated sub-grid standard deviations of surface wind speed agree well with reference results derived from 1 year of global weather analysis at 15 km resolution and from two regional model simulations with 3 km grid spacing.The wind-distribution-based emission calculations are implemented in CAM5. In terms of computational cost, the increase in total simulation time turns out to be less than 3 %. Simulations at 2° resolution indicate that sub-grid wind variability has relatively small impacts (about 7 % increase) on the global annual mean emission of sea salt aerosols, but considerable influence on the emission of dust. Among the considered mechanisms, dry convective eddies and mesoscale flows associated with topography are major causes of dust emission enhancement. With all the four mechanisms included and without additional adjustment of uncertain parameters in the model, the simulated global and annual mean dust emission increase by about 50 % compared to the default model. By tuning the globally constant dust emission scale factor, the global annual mean dust emission, aerosol optical depth, and top-of-atmosphere radiative fluxes can be adjusted to the level of the default model, but the frequency distribution of dust emission changes, with more contribution from weaker wind events and less contribution from stronger wind events. Lastly, in Africa and Asia, the overall frequencies of occurrence of dust emissions increase, and the seasonal variations are enhanced, while the geographical patterns of the emission frequency show little change.« less

  20. RE-PERG, a new procedure for electrophysiologic diagnosis of glaucoma that may improve PERG specificity.

    PubMed

    Mavilio, Alberto; Sisto, Dario; Ferreri, Paolo; Cardascia, Nicola; Alessio, Giovanni

    2017-01-01

    A significant variability of the second harmonic (2ndH) phase of steady-state pattern electroretinogram (SS-PERG) in intrasession retest has been recently described in glaucoma patients (GP), which has not been found in healthy subjects. To evaluate the reliability of phase variability in retest (a procedure called RE-PERG or REPERG) in the presence of cataract, which is known to affect standard PERG, we tested this procedure in GP, normal controls (NC), and cataract patients (CP). The procedure was performed on 50 GP, 35 NC, and 27 CP. All subjects were examined with RE-PERG and SS-PERG and also with spectral domain optical coherence tomography and standard automated perimetry. Standard deviation of phase and amplitude value of 2ndH were correlated by means of one-way analysis of variance and Pearson correlation, with the mean deviation and pattern standard deviation assessed by standard automated perimetry and retinal nerve fiber layer and the ganglion cell complex thickness assessed by spectral domain optical coherence tomography. Receiver operating characteristics were calculated in cohort populations with and without cataract. Standard deviation of phase of 2ndH was significantly higher in GP with respect to NC ( P <0.001) and CP ( P <0.001), and it correlated with retinal nerve fiber layer ( r =-0.5, P <0.001) and ganglion cell complex ( r =-0.6, P <0.001) defects in GP. Receiver operating characteristic evaluation showed higher specificity of RE-PERG (86.4%; area under the curve 0.93) with respect to SS-PERG (54.5%; area under the curve 0.68) in CP. RE-PERG may improve the specificity of SS-PERG in clinical practice in the discrimination of GP.

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