The Effects of Social Anxiety and State Anxiety on Visual Attention: Testing the Vigilance-Avoidance Hypothesis.

PubMed

Singh, J Suzanne; Capozzoli, Michelle C; Dodd, Michael D; Hope, Debra A

2015-01-01

A growing theoretical and research literature suggests that trait and state social anxiety can predict attentional patterns in the presence of emotional stimuli. The current study adds to this literature by examining the effects of state anxiety on visual attention and testing the vigilance-avoidance hypothesis, using a method of continuous visual attentional assessment. Participants were 91 undergraduate college students with high or low trait fear of negative evaluation (FNE), a core aspect of social anxiety, who were randomly assigned to either a high or low state anxiety condition. Participants engaged in a free view task in which pairs of emotional facial stimuli were presented and eye movements were continuously monitored. Overall, participants with high FNE avoided angry stimuli and participants with high state anxiety attended to positive stimuli. Participants with high state anxiety and high FNE were avoidant of angry faces, whereas participants with low state and low FNE exhibited a bias toward angry faces. The study provided partial support for the vigilance-avoidance hypothesis. The findings add to the mixed results in the literature that suggest that both positive and negative emotional stimuli may be important in understanding the complex attention patterns associated with social anxiety. Clinical implications and suggestions for future research are discussed.

Glass-to-cryogenic-liquid transitions in aqueous solutions suggested by crack healing

PubMed Central

Kim, Chae Un; Tate, Mark W.; Gruner, Sol M.

2015-01-01

Observation of theorized glass-to-liquid transitions between low-density amorphous (LDA) and high-density amorphous (HDA) water states had been stymied by rapid crystallization below the homogeneous water nucleation temperature (∼235 K at 0.1 MPa). We report optical and X-ray observations suggestive of glass-to-liquid transitions in these states. Crack healing, indicative of liquid, occurs when LDA ice transforms to cubic ice at 160 K, and when HDA ice transforms to the LDA state at temperatures as low as 120 K. X-ray diffraction study of the HDA to LDA transition clearly shows the characteristics of a first-order transition. Study of the glass-to-liquid transitions in nanoconfined aqueous solutions shows them to be independent of the solute concentrations, suggesting that they represent an intrinsic property of water. These findings support theories that LDA and HDA ice are thermodynamically distinct and that they are continuously connected to two different liquid states of water. PMID:26351671

Supervision Manual: Social Studies Program.

ERIC Educational Resources Information Center

Szabo, Lester John

This manual is designed to help school personnel implement a social studies program in grades K-12 in New York State. It provides the State mandates for social studies, recommends the scope and sequence of the social studies program, and suggests a procedure for implementing social studies revisions at the local level. How to form a local social…

Driver Cellphone and Texting Bans in the United States: Evidence of Effectiveness

PubMed Central

McCartt, Anne T.; Kidd, David G.; Teoh, Eric R.

2014-01-01

Almost all U.S. states have laws limiting drivers’ cellphone use. The evidence suggests that all-driver bans on hand-held phone conversations have resulted in long-term reductions in hand-held phone use, and drivers in ban states reported higher rates of hands-free phone use and lower overall phone use compared with drivers in non-ban states. Bans on all phone use by teenage drivers have not been shown to reduce their phone use. The effects of texting bans on the rates of drivers’ texting are unknown. With regard to the effects of bans on crashes, 11 peer-reviewed papers or technical reports of all-driver hand-held phone bans and texting bans were reviewed. Some were single-state studies examining crash measures before and after a state ban; other national or multi-state studies compared crashes in states with and without bans over time. The results varied widely. The lack of appropriate controls and other challenges in conducting strong evaluations limited the findings of some studies. Thus, despite the proliferation of laws limiting drivers’ cellphone use, it is unclear whether they are having the desired effects on safety. Priorities for future research are suggested. PMID:24776230

Sleep deprivation compromises resting-state emotional regulatory processes: An EEG study.

PubMed

Zhang, Jinxiao; Lau, Esther Yuet Ying; Hsiao, Janet H

2018-03-01

Resting-state spontaneous neural activities consume far more biological energy than stimulus-induced activities, suggesting their significance. However, existing studies of sleep loss and emotional functioning have focused on how sleep deprivation modulates stimulus-induced emotional neural activities. The current study aimed to investigate the impacts of sleep deprivation on the brain network of emotional functioning using electroencephalogram during a resting state. Two established resting-state electroencephalogram indexes (i.e. frontal alpha asymmetry and frontal theta/beta ratio) were used to reflect the functioning of the emotion regulatory neural network. Participants completed an 8-min resting-state electroencephalogram recording after a well-rested night or 24 hr sleep deprivation. The Sleep Deprivation group had a heightened ratio of the power density in theta band to beta band (theta/beta ratio) in the frontal area than the Sleep Control group, suggesting an effective approach with reduced frontal cortical regulation of subcortical drive after sleep deprivation. There was also marginally more left-lateralized frontal alpha power (left frontal alpha asymmetry) in the Sleep Deprivation group compared with the Sleep Control group. Besides, higher theta/beta ratio and more left alpha lateralization were correlated with higher sleepiness and lower vigilance. The results converged in suggesting compromised emotional regulatory processes during resting state after sleep deprivation. Our work provided the first resting-state neural evidence for compromised emotional functioning after sleep loss, highlighting the significance of examining resting-state neural activities within the affective brain network as a default functional mode in investigating the sleep-emotion relationship. © 2018 European Sleep Research Society.

Welfare policymaking and intersections of race, ethnicity, and gender in U.S. state legislatures.

PubMed

Reingold, Beth; Smith, Adrienne R

2012-01-01

Welfare policy in the American states has been shaped profoundly by race, ethnicity, and representation. Does gender matter as well? Focusing on state welfare reform in the mid-1990s, we test hypotheses derived from two alternative approaches to incorporating gender into the study of representation and welfare policymaking. An additive approach, which assumes gender and race/ethnicity are distinct and independent, suggests that female state legislators—regardless of race/ethnicity—will mitigate the more restrictive and punitive aspects of welfare reform, much like their African American and Latino counterparts do. In contrast, an intersectional approach, which highlights the overlapping and interdependent nature of gender and race/ethnicity, suggests that legislative women of color will have the strongest countervailing effect on state welfare reform—stronger than that of other women or men of color. Our empirical analyses suggest an intersectional approach yields a more accurate understanding of gender, race/ethnicity, and welfare politics in the states.

Reducing State Communication Anxiety for Public Speakers: An Energy Psychology Pilot Study

ERIC Educational Resources Information Center

Fitch, John, III; Schmuldt, Laura; Rudick, Karen L.

2011-01-01

This mixed-method pilot study investigates the efficacy of implementing primordial energy activation and transcendence to address public speaking anxiety. Speech anxiety was significantly reduced from pretest to posttest, as measured by the Communication Anxiety Inventory State. Suggestions for future research, limitations of the current study,…

State residence restrictions and forcible rape rates: a multistate quasi-experimental analysis of UCR data.

PubMed

Socia, Kelly M

2015-04-01

This study examines whether the presence of state residence restrictions resulted in changes in statewide rates of forcible rape. It builds on the limited geographic coverage of prior studies by including state-level Uniform Crime Report (UCR) data across 19 years for 49 states and the District of Columbia. It uses a quasi-experimental research method based on a longitudinal fixed-effects panel model design, which can help control for relatively static differences between states. Results indicate that when a state residence restriction was present, regardless of how it was measured, rates of UCR forcible rape were higher in the state than when the policy was not present. This suggests that residence restrictions, at least at the state level, are not useful as an overall crime prevention measure, but may be useful for increasing detection or reporting levels of such crimes. However, results also suggest that the size of the increase varied by whether the policy only applied to offenders with child victims or also included those with adult victims. Implications for research and policy are discussed. © The Author(s) 2013.

A Study of the Utility of Results from the 1992 Trial State Assessment (TSA) in Reading for State-Level Administrators of Assessment.

ERIC Educational Resources Information Center

Bullock, Cheryl Davis; DeStefano, Lizanne

1998-01-01

The usefulness of the 1992 TSA in reading was studied using interviews from 26 state directors of assessment. Perceptions about TSA credibility and orientation of test components and current use of TSA results were examined. The directors suggested involving more teachers in assessment, modifying descriptors, disseminating results quicker, and…

Dreaming and Schizophrenia.

ERIC Educational Resources Information Center

Stickney, Jeffrey L.

Parallels between dream states and schizophrenia suggest that the study of dreams may offer some information about schizophrenia. A major theoretical assumption of the research on dreaming and schizophrenia is that, in schizophrenics, the dream state intrudes on the awake state creating a dreamlike symptomatology. This theory, called the REM…

The Muted Voice of the Catholic Church in Angola

DTIC Science & Technology

2016-12-01

Mozambique despite a common colonial and religious heritage. The analysis suggests that state resistance to international influence, or gatekeeping, is a...freedoms, was weaker in Angola than in Brazil and Mozambique despite a common colonial and religious heritage. The analysis suggests that state resistance...through religious evangelization. Second, this study will shed light on how and why societies institutionalize religious values. Due to advancing

Protein-disulfide Isomerase Regulates the Thyroid Hormone Receptor-mediated Gene Expression via Redox Factor-1 through Thiol Reduction-Oxidation*

PubMed Central

Hashimoto, Shoko; Imaoka, Susumu

2013-01-01

Protein-disulfide isomerase (PDI) is a dithiol/disulfide oxidoreductase that regulates the redox state of proteins. We previously found that overexpression of PDI in rat pituitary tumor (GH3) cells suppresses 3,3′,5-triiodothyronine (T3)-stimulated growth hormone (GH) expression, suggesting the contribution of PDI to the T3-mediated gene expression via thyroid hormone receptor (TR). In the present study, we have clarified the mechanism of regulation by which TR function is regulated by PDI. Overexpression of wild-type but not redox-inactive mutant PDI suppressed the T3-induced GH expression, suggesting that the redox activity of PDI contributes to the suppression of GH. We considered that PDI regulates the redox state of the TR and focused on redox factor-1 (Ref-1) as a mediator of the redox regulation of TR by PDI. Interaction between Ref-1 and TRβ1 was detected. Overexpression of wild-type but not C64S Ref-1 facilitated the GH expression, suggesting that redox activity of Cys-64 in Ref-1 is involved in the TR-mediated gene expression. Moreover, PDI interacted with Ref-1 and changed the redox state of Ref-1, suggesting that PDI controls the redox state of Ref-1. Our studies suggested that Ref-1 contributes to TR-mediated gene expression and that the redox state of Ref-1 is regulated by PDI. Redox regulation of PDI via Ref-1 is a new aspect of PDI function. PMID:23148211

Bullying in Europe and the United States.

ERIC Educational Resources Information Center

Hoover, John H.; Juul, Kristen

1993-01-01

Examines nature and scope of group violence among children in schools on both sides of Atlantic Ocean. Reviews studies of student attitudes about victimization and offers suggestions for prevention and treatment of bullying. Focus is on studies on bullying undertaken in Europe, mostly Scandinavia, and in United States (Author/NB)

Requirements For Security Sector Reform Success

DTIC Science & Technology

2016-05-26

Advanced Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas 2016 Approved for public release...ACRONYM(S) School of Advanced Military Studies , Advanced Military Studies Program 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION...political and economic stability are required for Security Sector Reform (SSR) success over the long term. This study suggests that states with stable

Rethinking early Earth phosphorus geochemistry

PubMed Central

Pasek, Matthew A.

2008-01-01

Phosphorus is a key biologic element, and a prebiotic pathway leading to its incorporation into biomolecules has been difficult to ascertain. Most potentially prebiotic phosphorylation reactions have relied on orthophosphate as the source of phosphorus. It is suggested here that the geochemistry of phosphorus on the early Earth was instead controlled by reduced oxidation state phosphorus compounds such as phosphite (HPO32−), which are more soluble and reactive than orthophosphates. This reduced oxidation state phosphorus originated from extraterrestrial material that fell during the heavy bombardment period or was produced during impacts, and persisted in the mildly reducing atmosphere. This alternate view of early Earth phosphorus geochemistry provides an unexplored route to the formation of pertinent prebiotic phosphorus compounds, suggests a facile reaction pathway to condensed phosphates, and is consistent with the biochemical usage of reduced oxidation state phosphorus compounds in life today. Possible studies are suggested that may detect reduced oxidation state phosphorus compounds in ancient Archean rocks. PMID:18195373

Rethinking early Earth phosphorus geochemistry.

PubMed

Pasek, Matthew A

2008-01-22

Phosphorus is a key biologic element, and a prebiotic pathway leading to its incorporation into biomolecules has been difficult to ascertain. Most potentially prebiotic phosphorylation reactions have relied on orthophosphate as the source of phosphorus. It is suggested here that the geochemistry of phosphorus on the early Earth was instead controlled by reduced oxidation state phosphorus compounds such as phosphite (HPO(3)(2-)), which are more soluble and reactive than orthophosphates. This reduced oxidation state phosphorus originated from extraterrestrial material that fell during the heavy bombardment period or was produced during impacts, and persisted in the mildly reducing atmosphere. This alternate view of early Earth phosphorus geochemistry provides an unexplored route to the formation of pertinent prebiotic phosphorus compounds, suggests a facile reaction pathway to condensed phosphates, and is consistent with the biochemical usage of reduced oxidation state phosphorus compounds in life today. Possible studies are suggested that may detect reduced oxidation state phosphorus compounds in ancient Archean rocks.

The Contradictions of Uneven Development for States and Firms: Capital and State Rescaling in Peripheral Regions

ERIC Educational Resources Information Center

Quark, Amy Adams

2008-01-01

Recent studies suggest that processes of capital and state rescaling are generating new socio-spatial inequalities within nation-states. I explore rescaling in the understudied context of a peripheral region through the case of a global apparel merchant, Lands' End, and its decision to relocate its call and distribution centers to Dodgeville,…

State funding for local public health: observations from six case studies.

PubMed

Potter, Margaret A; Fitzpatrick, Tiffany

2007-01-01

The purpose of this study is to describe state funding of local public health within the context of state public health system types. These types are based on administrative relationships, legal structures, and relative proportion of state funding in local public health budgets. We selected six states representing various types and geographic regions. A case study for each state summarized available information and was validated by state public health officials. An analysis of the case studies reveals that the variability of state public health systems--even within a given type--is matched by variability in approaches to funding local public health. Nevertheless, some meaningful associations appear. For example, higher proportions of state funding occur along with higher levels of state oversight and the existence of local service mandates in state law. These associations suggest topics for future research on public health financing in relation to local accountability, local input to state priority-setting, mandated local services, and the absence of state funds for public health services in some local jurisdictions.

Posthypnotic state changes and flashbacks: analogous processes?

PubMed

Lovern, John

2012-01-01

Careful study of the posttraumatic stress disorder and hypnosis literatures reveals some parallels between posttraumatic flashbacks and responses to posthypnotic suggestions. Highly susceptible subjects can slip into hypnosis spontaneously and accept and respond to implied or inadvertent suggestions, some of which may operate in a manner equivalent to posthypnotic suggestions. Later, exposure to appropriate cues may trigger an intrusive revivification of the hypnotic state in which the suggestion occurred. This sequence of events closely resembles the sequence of reactions that some individuals have to trauma that ultimately leads to flashbacks. Thus, flashbacks may be conceived of as intrusive posttraumatic revivifications of trauma-induced hypnosis-like states that are reactivated by trauma-reminiscent cues operating similarly to posthypnotic signals. Implications of viewing flashbacks in this way, especially if this view is supported by future research, could include significant changes in how posttraumatic stress disorder is conceptualized and treated.

Modulation of Brain Resting-State Networks by Sad Mood Induction

PubMed Central

Harrison, Ben J.; Pujol, Jesus; Ortiz, Hector; Fornito, Alex; Pantelis, Christos; Yücel, Murat

2008-01-01

Background There is growing interest in the nature of slow variations of the blood oxygen level-dependent (BOLD) signal observed in functional MRI resting-state studies. In humans, these slow BOLD variations are thought to reflect an underlying or intrinsic form of brain functional connectivity in discrete neuroanatomical systems. While these ‘resting-state networks’ may be relatively enduring phenomena, other evidence suggest that dynamic changes in their functional connectivity may also emerge depending on the brain state of subjects during scanning. Methodology/Principal Findings In this study, we examined healthy subjects (n = 24) with a mood induction paradigm during two continuous fMRI recordings to assess the effects of a change in self-generated mood state (neutral to sad) on the functional connectivity of these resting-state networks (n = 24). Using independent component analysis, we identified five networks that were common to both experimental states, each showing dominant signal fluctuations in the very low frequency domain (∼0.04 Hz). Between the two states, we observed apparent increases and decreases in the overall functional connectivity of these networks. Primary findings included increased connectivity strength of a paralimbic network involving the dorsal anterior cingulate and anterior insula cortices with subjects' increasing sadness and decreased functional connectivity of the ‘default mode network’. Conclusions/Significance These findings support recent studies that suggest the functional connectivity of certain resting-state networks may, in part, reflect a dynamic image of the current brain state. In our study, this was linked to changes in subjective mood. PMID:18350136

Neural activity underlying motor-action preparation and cognitive narrowing in approach-motivated goal states.

PubMed

Gable, Philip A; Threadgill, A Hunter; Adams, David L

2016-02-01

High-approach-motivated (pre-goal) positive affect states encourage tenacious goal pursuit and narrow cognitive scope. As such, high approach-motivated states likely enhance the neural correlates of motor-action preparation to aid in goal acquisition. These neural correlates may also relate to the cognitive narrowing associated with high approach-motivated states. In the present study, we investigated motor-action preparation during pre-goal and post-goal states using an index of beta suppression over the motor cortex. The results revealed that beta suppression was greatest in pre-goal positive states, suggesting that higher levels of motor-action preparation occur during high approach-motivated positive states. Furthermore, beta and alpha suppression in the high approach-motivated positive states predicted greater cognitive narrowing. These results suggest that approach-motivated pre-goal states engage the neural substrates of motor-action preparation and cognitive narrowing. Individual differences in motor-action preparation relate to the degree of cognitive narrowing.

Decision making under uncertainty and information processing in positive and negative mood states.

PubMed

Mohanty, Sachi Nandan; Suar, Damodar

2014-08-01

This study examines whether mood states (a) influence decision making under uncertainty and (b) affect information processing. 200 students at the Indian Institute of Technology Kharagpur participated in this study. Positive mood was induced by showing comedy movie clips to 100 participants and negative mood was induced by showing tragedy movie clips to another 100 participants. The participants were administered a questionnaire containing hypothetical situations of financial gains and losses, and a health risk problem. The participants selected a choice for each situation, and stated the reasons for their choice. Results suggested that the participants preferred cautious choices in the domain of gain and in health risk problems and risky choices in the domain of loss. Analysis of the reasons for the participants' choices suggested more fluency, originality, and flexibility of information in a negative mood compared to a positive mood. A negative (positive) mood state facilitated systematic (heuristic) information processing.

Establishing low-lying doubly charmed baryons

NASA Astrophysics Data System (ADS)

Chen, Hua-Xing; Mao, Qiang; Chen, Wei; Liu, Xiang; Zhu, Shi-Lin

2017-08-01

We systematically study the S -wave doubly charmed baryons using the method of QCD sum rules. Our results suggest that the Ξcc ++ recently observed by LHCb can be well identified as the S -wave Ξc c state of JP=1 /2+. We study its relevant Ωc c state, the mass of which is predicted to be around 3.7 GeV. We also systematically study the P -wave doubly charmed baryons, the masses of which are predicted to be around 4.1 GeV. Especially, there can be several excited doubly charmed baryons in this energy region, and we suggest searching for them in order to study the fine structure of the strong interaction.

Financial Aid and Attainment among Students in a State with Changing Demographics

ERIC Educational Resources Information Center

Gross, Jacob P. K.; Torres, Vasti; Zerquera, Desiree

2013-01-01

Using event history analysis, this study investigated to what extent differentiated forms of aid affected the educational attainment of various student populations with particular interest on the Latinos/as within this emerging settlement state: Indiana. Findings suggest that the effects of aid are moderated by race and ethnicity. State grants,…

The Next Generation of State Assessment and Accountability

ERIC Educational Resources Information Center

Rothman, Robert; Marion, Scott F.

2016-01-01

A pilot program in New Hampshire models innovative ways creating and applying state assessments and educator accountability. A study of New Hampshire's new system, which has already received approval by the U.S. Department of Education under a waiver from NCLB, finds some positive results and also suggests challenges states might face in putting…

How Psychological States Affect the Immune System: Implications for Interventions in the Context of HIV.

ERIC Educational Resources Information Center

Littrell, Jill

1996-01-01

Discusses the psychological states associated with enhanced immune system functioning and those associated with suppressed immune functioning. Reviews studies of psychological and behavioral interventions to boost the immune systems of people who are HIV positive. Suggests that group interventions can enhance psychological states associated with…

An Instructional Method Suggestion: Conveying Stories through Origami (Storigami)

ERIC Educational Resources Information Center

Oguz, Aysegul

2016-01-01

The purpose of this study was to elucidate how to convey stories through origami and suggest its use in education with the help of pre-service elementary teachers' opinions. The participants of the study were 103 elementary teacher candidates from a state university in the 2014-2015 academic year. In this qualitative study, the data were collected…

Supporting Novice Teachers through Mentoring and Induction in the United States

ERIC Educational Resources Information Center

Zembytska, Maryna

2015-01-01

The study focuses on the U.S. system of novice teacher support. The study highlights the evolution of mentoring from a traditional, isolated, hierarchical one-to-one relationship to multiple interactions which comprise a collaborative developmental network. The findings suggest that mentoring and induction support in the United States are…

Influence of Leader Behaviors on Creativity: A Comparative Study between South Korea and the United States

ERIC Educational Resources Information Center

Hwang, Seog Joo

2013-01-01

This study investigates what are the relationships between different leader behaviors (i.e. supportive, participative, and controlling leader behaviors) and follower creativity, and whether the relationships differ between South Korea and the United States. Although creativity research suggests that supportive leader behaviors tend to enhance…

Living in-Between: Chinese Sojourner Families' Experiences in the United States

ERIC Educational Resources Information Center

Chen, Xiaoning

2013-01-01

This ethnographic study closely examines Chinese sojourner families' experiences in the United States. While immigrant children's home and school experiences have been documented, this study extends the literature by highlighting the unique needs and challenges of sojourner children and their parents. The findings suggest that it is critical for…

Stress among Secondary School Teachers in Ebonyi State, Nigeria: Suggested Interventions in the Worksite Milieu

ERIC Educational Resources Information Center

Nwimo, Ignatius O.; Onwunaka, Chinagorom

2015-01-01

The aim of the study was to determine the level of stress experienced by secondary school teachers in Ebonyi State. The dimensions of stress studied included physical stress, mental stress, emotional stress and social stress. The study adopted the cross-sectional survey design using a sample of 660 (male 259, female 401) teachers randomly drawn…

Ideas for Studying About the United States in Europe.

ERIC Educational Resources Information Center

Wright, David

1986-01-01

Suggests six activities for teaching United Kingdom students about the United States and vice versa. Ideas include word associations, map and globe work to discover climate and habitation patterns, exchange of student projects, and relevant textbook passages. (JDH)

The relationship between ego-state and communication skills in medical students.

PubMed

Hur, Yera; Cho, A-Ra

2014-03-01

The purpose of this study was to examine the relationship between ego-states and communication skills in medical students. A total of 109 medical school students participated in this study, which used the communication skills self-test papers and the Egogram checklist. The data were analyzed by frequency analysis, and Pearson correlation analysis. Ego-state was related to communication skills. In particular, adapted child ego-state was negatively associated with each sphere of communication skills. Our results suggested that ego-state types should be considered in developing a communication skills education program for medical students.

Does resting-state connectivity reflect depressive rumination? A tale of two analyses.

PubMed

Berman, Marc G; Misic, Bratislav; Buschkuehl, Martin; Kross, Ethan; Deldin, Patricia J; Peltier, Scott; Churchill, Nathan W; Jaeggi, Susanne M; Vakorin, Vasily; McIntosh, Anthony R; Jonides, John

2014-12-01

Major Depressive Disorder (MDD) is characterized by rumination. Prior research suggests that resting-state brain activation reflects rumination when depressed individuals are not task engaged. However, no study has directly tested this. Here we investigated whether resting-state epochs differ from induced ruminative states for healthy and depressed individuals. Most previous research on resting-state networks comes from seed-based analyses with the posterior cingulate cortex (PCC). By contrast, we examined resting state connectivity by using the complete multivariate connectivity profile (i.e., connections across all brain nodes) and by comparing these results to seeded analyses. We find that unconstrained resting-state intervals differ from active rumination states in strength of connectivity and that overall connectivity was higher for healthy vs. depressed individuals. Relationships between connectivity and subjective mood (i.e., behavior) were strongly observed during induced rumination epochs. Furthermore, connectivity patterns that related to subjective mood were strikingly different for MDD and healthy control (HC) groups suggesting different mood regulation mechanisms. Copyright © 2014 Elsevier Inc. All rights reserved.

Detailed spectroscopy of 110Cd: Evidence for weak mixing and the emergence of γ-soft behavior

NASA Astrophysics Data System (ADS)

Garrett, P. E.; Bangay, J.; Diaz Varela, A.; Ball, G. C.; Cross, D. S.; Demand, G. A.; Finlay, P.; Garnsworthy, A. B.; Green, K. L.; Hackman, G.; Hannant, C. D.; Jigmeddorj, B.; Jolie, J.; Kulp, W. D.; Leach, K. G.; Orce, J. N.; Phillips, A. A.; Radich, A. J.; Rand, E. T.; Schumaker, M. A.; Svensson, C. E.; Sumithrarachchi, C.; Triambak, S.; Warr, N.; Wong, J.; Wood, J. L.; Yates, S. W.

2012-10-01

A study of the β+-electron capture decay of 110In into levels of 110Cd is combined with a reanalysis of data from a previous study of 110Cd with the (n,n'γ) reaction with monoenergetic neutrons. The γγ coincidences from the 110In decay leads to many new assignments of γ rays observed in the (n,n'γ) reaction, permitting the observation of weak low-energy transitions, and setting stringent upper limits on unobserved decay branches. The uncertainties on many of the lifetimes from the (n,n'γ) reaction are significantly reduced, and limits are established for the lifetimes of levels too long for a direct measurement. The absence of enhanced transitions between the previously assigned phonon states and the deformed intruder states strongly suggests that mixing between the configurations is generally weak, refuting the strong-mixing scenario as an explanation of the decay pattern of the excited 0+ states in 110Cd. The decay pattern of the nonintruder states is suggestive of a γ-soft rotor, or O(6) nucleus, rather than a vibrational, or U(5), pattern. The existence of a four-particle-six-hole proton excitation in 110Cd is also suggested.

Small-Angle X-ray Scattering and Single-Molecule FRET Spectroscopy Produce Highly Divergent Views of the Low-Denaturant Unfolded State

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoo, Tae Yeon; Meisburger, Steve P.; Hinshaw, James

2012-10-10

The results of more than a dozen single-molecule Foerster resonance energy transfer (smFRET) experiments suggest that chemically unfolded polypeptides invariably collapse from an expanded random coil to more compact dimensions as the denaturant concentration is reduced. In sharp contrast, small-angle X-ray scattering (SAXS) studies suggest that, at least for single-domain proteins at non-zero denaturant concentrations, such compaction may be rare. Here, we explore this discrepancy by studying protein L, a protein previously studied by SAXS (at 5 C), which suggested fixed unfolded-state dimensions from 1.4 to 5 M guanidine hydrochloride (GuHCl), and by smFRET (at 25 C), which suggested that,more » in contrast, the chain contracts by 15-30% over this same denaturant range. Repeating the earlier SAXS study under the same conditions employed in the smFRET studies, we observe little, if any, evidence that the unfolded state of protein L contracts as the concentration of GuHCl is reduced. For example, scattering profiles (and thus the shape and dimensions) collected within {approx} 4 ms after dilution to as low as 0.67 M GuHCl are effectively indistinguishable from those observed at equilibrium at higher denaturant. Our results thus argue that the disagreement between SAXS and smFRET is statistically significant and that the experimental evidence in favor of obligate polypeptide collapse at low denaturant cannot be considered conclusive yet.« less

Private Giving and State Funding of Maryland's Public Institutions: New Perspectives on Support of Historically Black Institutions

ERIC Educational Resources Information Center

Cox, John L.

2010-01-01

College leaders and policymakers benefit by understanding the relationship between increases in private giving, changes in state appropriations and how to position the institution to maximize both sources of revenue. Anecdotal and attitudinal studies suggested that fundraising success may affect state funding of higher education institutions.…

Structural and functional cerebral correlates of hypnotic suggestibility.

PubMed

Huber, Alexa; Lui, Fausta; Duzzi, Davide; Pagnoni, Giuseppe; Porro, Carlo Adolfo

2014-01-01

Little is known about the neural bases of hypnotic suggestibility, a cognitive trait referring to the tendency to respond to hypnotic suggestions. In the present magnetic resonance imaging study, we performed regression analyses to assess hypnotic suggestibility-related differences in local gray matter volume, using voxel-based morphometry, and in waking resting state functional connectivity of 10 resting state networks, in 37 healthy women. Hypnotic suggestibility was positively correlated with gray matter volume in portions of the left superior and medial frontal gyri, roughly overlapping with the supplementary and pre-supplementary motor area, and negatively correlated with gray matter volume in the left superior temporal gyrus and insula. In the functional connectivity analysis, hypnotic suggestibility was positively correlated with functional connectivity between medial posterior areas, including bilateral posterior cingulate cortex and precuneus, and both the lateral visual network and the left fronto-parietal network; a positive correlation was also found with functional connectivity between the executive-control network and a right postcentral/parietal area. In contrast, hypnotic suggestibility was negatively correlated with functional connectivity between the right fronto-parietal network and the right lateral thalamus. These findings demonstrate for the first time a correlation between hypnotic suggestibility, the structural features of specific cortical regions, and the functional connectivity during the normal resting state of brain structures involved in imagery and self-monitoring activity.

What goes on in the resting-state? A qualitative glimpse into resting-state experience in the scanner

PubMed Central

Hurlburt, Russell T.; Alderson-Day, Ben; Fernyhough, Charles; Kühn, Simone

2015-01-01

The brain’s resting-state has attracted considerable interest in recent years, but currently little is known either about typical experience during the resting-state or about whether there are inter-individual differences in resting-state phenomenology. We used descriptive experience sampling (DES) in an attempt to apprehend high fidelity glimpses of the inner experience of five participants in an extended fMRI study. Results showed that the inner experiences and the neural activation patterns (as quantified by amplitude of low frequency fluctuations analysis) of the five participants were largely consistent across time, suggesting that our extended-duration scanner sessions were broadly similar to typical resting-state sessions. However, there were very large individual differences in inner phenomena, suggesting that the resting-state itself may differ substantially from one participant to the next. We describe these individual differences in experiential characteristics and display some typical moments of resting-state experience. We also show that retrospective characterizations of phenomena can often be very different from moment-by-moment reports. We discuss implications for the assessment of inner experience in neuroimaging studies more generally, concluding that it may be possible to use fMRI to investigate neural correlates of phenomena apprehended in high fidelity. PMID:26500590

Synchrony, Weather, and Cycles in Southern Pine Beetle (Coleoptera: Curculionidae).

PubMed

Reeve, John D

2018-02-08

Spatial synchrony and cycles are common features of forest insect pests, but are often studied as separate phenomenon. Using time series of timber damage caused by Dendroctonus frontalis Zimmermann (Coleoptera: Curculionidae) (southern pine beetle) in 10 states within the southern United States, this study examines synchrony in D. frontalis abundance, the synchronizing effects of temperature extremes, and the evidence for shared cycles among state populations. Cross-correlation and cluster analyses are used to quantify synchrony across a range of geographic distances and to identify groups of states with synchronous dynamics. Similar techniques are used to quantify spatial synchrony in temperature extremes and to examine their relationship to D. frontalis fluctuations. Cross-wavelet analysis is then used to examine pairs of time series for shared cycles. These analyses suggest there is substantial synchrony among states in D. frontalis fluctuations, and there are regional groups of states with similar dynamics. Synchrony in D. frontalis fluctuations also appears related to spatial synchrony in summer and winter temperature extremes. The cross-wavelet results suggest that D. frontalis dynamics may differ among regions and are not stationary. Significant oscillations were present in some states over certain time intervals, suggesting an endogenous feedback mechanism. Management of D. frontalis outbreaks could potentially benefit from a multistate regional approach because populations are synchronous on this level. Extreme summer temperatures are likely to become the most important synchronizing agent due to climate change. © The Author(s) 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Lacosamide Inhibition of Nav1.7 Voltage-Gated Sodium Channels: Slow Binding to Fast-Inactivated States

PubMed Central

Jo, Sooyeon

2017-01-01

Lacosamide is an antiseizure agent that targets voltage-dependent sodium channels. Previous experiments have suggested that lacosamide is unusual in binding selectively to the slow-inactivated state of sodium channels, in contrast to drugs like carbamazepine and phenytoin, which bind tightly to fast-inactivated states. Using heterologously expressed human Nav1.7 sodium channels, we examined the state-dependent effects of lacosamide. Lacosamide induced a reversible shift in the voltage dependence of fast inactivation studied with 100-millisecond prepulses, suggesting binding to fast-inactivated states. Using steady holding potentials, lacosamide block was very weak at −120 mV (3% inhibition by 100 µM lacosamide) but greatly enhanced at −80 mV (43% inhibition by 100 µM lacosamide), where there is partial fast inactivation but little or no slow inactivation. During long depolarizations, lacosamide slowly (over seconds) put channels into states that recovered availability slowly (hundreds of milliseconds) at −120 mV. This resembles enhancement of slow inactivation, but the effect was much more pronounced at −40 mV, where fast inactivation is complete, but slow inactivation is not, than at 0 mV, where slow inactivation is maximal, more consistent with slow binding to fast-inactivated states than selective binding to slow-inactivated states. Furthermore, inhibition by lacosamide was greatly reduced by pretreatment with 300 µM lidocaine or 300 µM carbamazepine, suggesting that lacosamide, lidocaine, and carbamazepine all bind to the same site. The results suggest that lacosamide binds to fast-inactivated states in a manner similar to other antiseizure agents but with slower kinetics of binding and unbinding. PMID:28119481

Lacosamide Inhibition of Nav1.7 Voltage-Gated Sodium Channels: Slow Binding to Fast-Inactivated States.

PubMed

Jo, Sooyeon; Bean, Bruce P

2017-04-01

Lacosamide is an antiseizure agent that targets voltage-dependent sodium channels. Previous experiments have suggested that lacosamide is unusual in binding selectively to the slow-inactivated state of sodium channels, in contrast to drugs like carbamazepine and phenytoin, which bind tightly to fast-inactivated states. Using heterologously expressed human Nav1.7 sodium channels, we examined the state-dependent effects of lacosamide. Lacosamide induced a reversible shift in the voltage dependence of fast inactivation studied with 100-millisecond prepulses, suggesting binding to fast-inactivated states. Using steady holding potentials, lacosamide block was very weak at -120 mV (3% inhibition by 100 µ M lacosamide) but greatly enhanced at -80 mV (43% inhibition by 100 µ M lacosamide), where there is partial fast inactivation but little or no slow inactivation. During long depolarizations, lacosamide slowly (over seconds) put channels into states that recovered availability slowly (hundreds of milliseconds) at -120 mV. This resembles enhancement of slow inactivation, but the effect was much more pronounced at -40 mV, where fast inactivation is complete, but slow inactivation is not, than at 0 mV, where slow inactivation is maximal, more consistent with slow binding to fast-inactivated states than selective binding to slow-inactivated states. Furthermore, inhibition by lacosamide was greatly reduced by pretreatment with 300 µ M lidocaine or 300 µ M carbamazepine, suggesting that lacosamide, lidocaine, and carbamazepine all bind to the same site. The results suggest that lacosamide binds to fast-inactivated states in a manner similar to other antiseizure agents but with slower kinetics of binding and unbinding. Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics.

Down-regulating narcissistic tendencies: communal focus reduces state narcissism.

PubMed

Giacomin, Miranda; Jordan, Christian H

2014-04-01

Narcissism has been conceptualized as a set of coherent, mutually reinforcing attributes that orients individuals toward self-enhancement and positive self-feelings. In this view, reducing one element of narcissism--such as a greater concern for agency than communion--may situationally reduce narcissism in a state-like manner. Across five studies, we found that increasing communal focus toward others decreases state narcissism. In Study 1, participants induced to feel empathy reported less state narcissism. In Studies 2 to 4, participants primed with interdependent self-construal reported less state narcissism than control participants and those primed with independent self-construal. Furthermore, in Study 4, changes in state narcissism mediated changes in desire for fame and perceptions that others deserve help. Thus, changes in one element of narcissism may situationally reduce narcissistic tendencies. These findings suggest that narcissism is more state-like and context-dependent than previously assumed.

Heat resistance of viable but non-culturable Escherichia coli cells determined by differential scanning calorimetry.

PubMed

Castro-Rosas, Javier; Gómez-Aldapa, Carlos Alberto; Villagómez Ibarra, José Roberto; Santos-López, Eva María; Rangel-Vargas, Esmeralda

2017-10-16

Several reports have suggested that the viable but non-culturable (VBNC) state is a resistant form of bacterial cells that allows them to remain in a dormant form in the environment. Nevertheless, studies on the resistance of VBNC bacterial cells to ecological factors are limited, mainly because techniques that allow this type of evaluation are lacking. Differential scanning calorimetry (DSC) has been used to study the thermal resistance of culturable bacteria but has never been used to study VBNC cells. In this work, the heat resistance of Escherichia coli cells in the VBNC state was studied using the DSC technique. The VBNC state was induced in E. coli ATCC 25922 by suspending bacterial cells in artificial sea water, followed by storage at 3 ± 2°C for 110 days. Periodically, the behaviour of E. coli cells was monitored by plate counts, direct viable counts and DSC. The entire bacterial population entered the VBNC state after 110 days of storage. The results obtained with DSC suggest that the VBNC state does not confer thermal resistance to E. coli cells in the temperature range analysed here. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

A Changing Number of Alternative States in the Boreal Biome: Reproducibility Risks of Replacing Remote Sensing Products.

PubMed

Xu, Chi; Holmgren, Milena; Van Nes, Egbert H; Hirota, Marina; Chapin, F Stuart; Scheffer, Marten

2015-01-01

Publicly available remote sensing products have boosted science in many ways. The openness of these data sources suggests high reproducibility. However, as we show here, results may be specific to versions of the data products that can become unavailable as new versions are posted. We focus on remotely-sensed tree cover. Recent studies have used this public resource to detect multi-modality in tree cover in the tropical and boreal biomes. Such patterns suggest alternative stable states separated by critical tipping points. This has important implications for the potential response of these ecosystems to global climate change. For the boreal region, four distinct ecosystem states (i.e., treeless, sparse and dense woodland, and boreal forest) were previously identified by using the Collection 3 data of MODIS Vegetation Continuous Fields (VCF). Since then, the MODIS VCF product has been updated to Collection 5; and a Landsat VCF product of global tree cover at a fine spatial resolution of 30 meters has been developed. Here we compare these different remote-sensing products of tree cover to show that identification of alternative stable states in the boreal biome partly depends on the data source used. The updated MODIS data and the newer Landsat data consistently demonstrate three distinct modes around similar tree-cover values. Our analysis suggests that the boreal region has three modes: one sparsely vegetated state (treeless), one distinct 'savanna-like' state and one forest state, which could be alternative stable states. Our analysis illustrates that qualitative outcomes of studies may change fundamentally as new versions of remote sensing products are used. Scientific reproducibility thus requires that old versions remain publicly available.

Association between long work hours and depressive state: a pilot study of propensity score matched Japanese white-collar workers.

PubMed

Uchida, Mitsuo; Morita, Hiroshi

2018-06-01

Although long work hours have been associated with various physical health problems, studies of their association with mental health have yielded inconsistent results, due to differences in study settings, study outcome and/or unmeasured background factors. In this study, we used a propensity score method to evaluate the association between work hours and depressive state. A total of 467 Japanese white-collar workers were surveyed and divided into long and regular work hour groups according to overtime work records. Propensity score matching was performed based on 32 individual background and workplace factors, yielding 74 pairs of propensity-matched subjects. CES-D score, an indicator of depressive state, did not differ significantly among the two groups (p=0.203). However, work motivation, work control, social support and emotional stability correlated with CES-D score. These findings suggest that work control and social support factors are more associated with depressive state than control of work hours. These results also suggest that it is possible to use propensity score matching to evaluate the association between work hours and mental health in occupational study settings. Further studies, in larger populations, are required to determine the association between work hours and mental health parameters.

The relationship between suggestibility and anxiety among suspects detained at police stations.

PubMed

Gudjonsson, G H; Rutter, S C; Clare, I C

1995-07-01

The present study investigated the relationship between anxiety, as measured by the State-Trait Inventory (Spielberger, 1983) and interrogative suggestibility, as measured by the Gudjonsson Suggestibility Scale (GSS 2, Gudjonsson, 1987). One hundred and sixty-one suspects detained at two English police stations for questioning were assessed prior to being interviewed by the police. Unexpectedly, trait anxiety correlated more consistently with suggestibility than did state anxiety. The correlations were consistently higher among the Caucasian than the Afro-Caribbean subjects and the Afro-Caribbean subjects were significantly more suggestible than the Caucasian subjects even after their GSS 2 memory and IQ scores had been controlled for. The main practical implications of the findings are that interrogative suggestibility cannot be easily evaluated from the person's self-reported anxiety and the situation in which people are assessed may influence the relationship between these psychological variables.

Suggestibility, expectancy, trance state effects, and hypnotic depth: II. Assessment via the PCI-HAP.

PubMed

Pekala, Ronald J; Kumar, V K; Maurer, Ronald; Elliott-Carter, Nancy; Moon, Edward; Mullen, Karen

2010-04-01

This study sought to determine if self-reported hypnotic depth (srHD) could be predicted from the variables of the Phenomenology of Consciousness Inventory - Hypnotic Assessment Procedure (PCI-HAP) (Pekala, 1995a, 1995b; Pekala & Kumar, 2007; Pekala et al., 2010), assessing several of the processes theorized by researchers to be associated with hypnotism: trance (altered state effects), suggestibility, and expectancy. One hundred and eighty participants completed the PCI-HAP. Using regression analyses, srHD scores were predicted from the PCI-HAP pre-hypnotic and post-hypnotic assessment items, and several other variables. The results suggested that the srHD scores were found to be a function of imagoic suggestibility, expectancy (both estimated hypnotic depth and expected therapeutic efficacy), and trance state and eye catalepsy effects; effects that appear to be additive and not (statistically) interactive. The results support the theorizing of many investigators concerning the involvement of the aforementioned component processes with this particular aspect of hypnotism, the self-reported hypnotic depth score.

Resting state low-frequency fluctuations in prefrontal cortex reflect degrees of harm avoidance and novelty seeking: an exploratory NIRS study

PubMed Central

Nakao, Takashi; Matsumoto, Tomoya; Shimizu, Daisuke; Morita, Machiko; Yoshimura, Shinpei; Northoff, Georg; Morinobu, Shigeru; Okamoto, Yasumasa; Yamawaki, Shigeto

2013-01-01

Harm avoidance (HA) and novelty seeking (NS) are temperament dimensions defined by Temperament and Character Inventory (TCI), respectively, reflecting a heritable bias for intense response to aversive stimuli or for excitement in response to novel stimuli. High HA is regarded as a risk factor for major depressive disorder and anxiety disorder. In contrast, higher NS is linked to increased risk for substance abuse and pathological gambling disorder. A growing body of evidence suggests that patients with these disorders show abnormality in the power of slow oscillations of resting-state brain activity. It is particularly interesting that previous studies have demonstrated that resting state activities in medial prefrontal cortex (MPFC) are associated with HA or NS scores, although the relation between the power of resting state slow oscillations and these temperament dimensions remains poorly elucidated. This preliminary study investigated the biological bases of these temperament traits by particularly addressing the resting state low-frequency fluctuations in MPFC. Regional hemodynamic changes in channels covering MPFC during 5-min resting states were measured from 22 healthy participants using near-infrared spectroscopy (NIRS). These data were used for correlation analyses. Results show that the power of slow oscillations during resting state around the dorsal part of MPFC is negatively correlated with the HA score. In contrast, NS was positively correlated with the power of resting state slow oscillations around the ventral part of MPFC. These results suggest that the powers of slow oscillation at rest in dorsal or ventral MPFC, respectively, reflect the degrees of HA and NS. This exploratory study therefore uncovers novel neural bases of HA and NS. We discuss a neural mechanism underlying aversion-related and reward-related processing based on results obtained from this study. PMID:24381545

Activities for Teaching State, County, and Municipal Government: A Curriculum Guide for Understanding State, County, and Municipal Government in Oklahoma.

ERIC Educational Resources Information Center

Hopkins, Michael J., Ed.; Wright, Clifford, Ed.

The intent of this curriculum guide is to suggest objectives, teaching methods, and learning activities to aid social studies classroom teachers at the elementary and secondary levels as they incorporate material on state, county, and municipal governments into the curriculum. Although developed for use in Oklahoma public schools, the guide can…

International Students: A Comparison of Health Status and Physical Health before and after Coming to the United States

ERIC Educational Resources Information Center

Msengi, Clementine M.; Msengi, Israel G.; Harris, Sandra; Hopson, Michael

2011-01-01

The purpose of this study was to assess the health status and physical health of international students at five American universities. International students in the United States were asked to compare the status of their health before and after coming to the United States. Findings suggested that health status of international students declined…

Services and Supports for Students with Traumatic Brain Injury: Survey of State Educational Agencies

ERIC Educational Resources Information Center

Glang, Ann; Ettel, Deborah; Todis, Bonnie; Gordon, Wayne A.; Oswald, Jennifer M.; Vaughn, Susan L.; Connors, Susan H.; Brown, Margaret

2015-01-01

Long-term follow-up studies conducted during the K-12 school years suggest that challenges related to childhood traumatic brain injury (TBI) tend to persist or worsen over time. A 1999 survey of State Directors of Special Education revealed that most states had emerging initiatives for children with TBI and were expanding their capacity to serve…

Constraints and Suggestions in Adopting Seasonal Climate Forecasts by Farmers in South India

ERIC Educational Resources Information Center

Shankar, K. Ravi; Nagasree, K.; Venkateswarlu, B.; Maraty, Pochaiah

2011-01-01

The main objective of this study was to determine constraints and suggestions of farmers towards adopting seasonal climate forecasts. It addresses the question: Which forms of providing forecasts will be helpful to farmers in agricultural decision making? For the study, farmers were selected from Andhra Pradesh state of South India. One hundred…

Do Portuguese and UK health state values differ across valuation methods?

PubMed

Ferreira, Lara N; Ferreira, Pedro L; Rowen, Donna; Brazier, John E

2011-05-01

There has been an increasing interest in developing country-specific preference weights for widely used measures of health-related quality of life. The valuation of health states has usually been done using cardinal preference elicitation techniques of standard gamble (SG) or time trade-off (TTO). Yet there is increasing interest in the use of ordinal methods to elicit health state utility values as an alternative to the more conventional cardinal techniques.This raises the issue of firstly whether ordinal and cardinal methods of preference elicitation provide similar results and secondly whether this relationship is robust across different valuation studies and different populations. This study examines SG and rank preference weights for the SF-6D derived from samples of the UK and Portuguese general population. The preference weights for the Portuguese sample (n = 140) using rank data are estimated here with 810 health state valuations. The study further examines whether the use of these different preference weights has an impact when comparing the health of different age and severity groups in the Portuguese working population (n = 2,459). The rank model performed well across the majority of measures of goodness of fit used. The preference weights for the Portuguese sample using rank data are systematically lower than the UK weights for physical functioning and pain. Yet our results suggest higher similarity between preference weights derived using rank data than using standard gamble across the UK and Portuguese samples. Our results further suggest that the SF-6D values for a sample of the Portuguese working-age population and differences across groups are affected by the use of different preference weights. We suggest that the use of a Portuguese SF-6D weighting system is preferred for studies aiming to reflect the health state preferences of the Portuguese population.

Comparing Teachers' Views on Morality and Moral Education, a Comparative Study in Turkey and the United States

ERIC Educational Resources Information Center

LePage, Pamela; Akar, Hanife; Temli, Yeliz; Sen, Derya; Hasser, Neil; Ivins, Ilene

2011-01-01

In this study, the researchers examined how K-8 teachers approach morality, moral education, and the moral development of children in Turkey and in the United States. Both countries have diverse cultures and long histories with secular education systems. Surveys were sent to teachers in nine cities in both countries. Results suggest that Turkish…

Parental Perceptions toward and Practices of Heritage Language Maintenance: Focusing on the United States and Canada

ERIC Educational Resources Information Center

Liang, Feng

2018-01-01

This study reviews 17 studies since the year of 2000 on the perceptions and practices of immigrant parents who reside in the United States or Canada with respect to their children's heritage language maintenance (HLM). The findings suggest that parental perceptions may change due to practical considerations and vary with different degrees of…

Returning to Russia. The 1998 Career Guide for Russian Graduates of American Universities. Second Edition.

ERIC Educational Resources Information Center

Institute of International Education, New York, NY.

This book, for students returning to Russia after study in the United States, contains practical suggestions on looking for a job and writing resumes, information on the job market in Russia, advice from returned graduate students, and statistical data about Russian students studying in the United States. It also profiles companies that have…

Study of transitional doubly-odd /sup 186/Ir and /sup 184/Ir

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ben Braham, A.; Bourgeois, C.; Kilcher, P.

1987-12-10

The transitional doubly-odd iridium nuclei with A = 184 and 186 have been studied from the ..beta../sup +//EC decay of the corresponding platinum isotopes using the on-line mass separator ISOCELE. Configurations can be reasonably Attributed to the low-lying states of /sup 184/Ir in agreement with results already known. On the other hand an E3 transition observed in /sup 186/Ir suggests that the known long-lived 1.7h 2/sup -/ state is located at 137.5 keV above the 16h 5/sup +/ state, raising questions about structure of this latter state.

Measuring Generalized Expectancies for Negative Mood Regulation.

ERIC Educational Resources Information Center

Catanzaro, Salvatore J.; Mearns, Jack

Research has suggested the utility of studying individual differences in the regulation of negative mood states. Generalized response expectancies for negative mood regulation were defined as expectancies that some overt behavior or cognition would alleviate negative mood states as they occur across situations. The Generalized Expectancy for…

Infectious laryngotracheitis genomics: What’s circulating in the backyard flocks from the United States?

USDA-ARS?s Scientific Manuscript database

Phylogenetic and comparative genomic studies of infectious laryngotracheitis virus (ILTV) has mainly focused on the differences among live attenuated vaccines, vicinal revertants and natural recombinant strains from Australia, the United States, and China. This analysis suggests that most strains fr...

Structural and Functional Cerebral Correlates of Hypnotic Suggestibility

PubMed Central

Huber, Alexa; Lui, Fausta; Duzzi, Davide; Pagnoni, Giuseppe; Porro, Carlo Adolfo

2014-01-01

Little is known about the neural bases of hypnotic suggestibility, a cognitive trait referring to the tendency to respond to hypnotic suggestions. In the present magnetic resonance imaging study, we performed regression analyses to assess hypnotic suggestibility-related differences in local gray matter volume, using voxel-based morphometry, and in waking resting state functional connectivity of 10 resting state networks, in 37 healthy women. Hypnotic suggestibility was positively correlated with gray matter volume in portions of the left superior and medial frontal gyri, roughly overlapping with the supplementary and pre-supplementary motor area, and negatively correlated with gray matter volume in the left superior temporal gyrus and insula. In the functional connectivity analysis, hypnotic suggestibility was positively correlated with functional connectivity between medial posterior areas, including bilateral posterior cingulate cortex and precuneus, and both the lateral visual network and the left fronto-parietal network; a positive correlation was also found with functional connectivity between the executive-control network and a right postcentral/parietal area. In contrast, hypnotic suggestibility was negatively correlated with functional connectivity between the right fronto-parietal network and the right lateral thalamus. These findings demonstrate for the first time a correlation between hypnotic suggestibility, the structural features of specific cortical regions, and the functional connectivity during the normal resting state of brain structures involved in imagery and self-monitoring activity. PMID:24671130

Hypnotism as a Function of Trance State Effects, Expectancy, and Suggestibility: An Italian Replication.

PubMed

Pekala, Ronald J; Baglio, Francesca; Cabinio, Monia; Lipari, Susanna; Baglio, Gisella; Mendozzi, Laura; Cecconi, Pietro; Pugnetti, Luigi; Sciaky, Riccardo

2017-01-01

Previous research using stepwise regression analyses found self-reported hypnotic depth (srHD) to be a function of suggestibility, trance state effects, and expectancy. This study sought to replicate and expand that research using a general state measure of hypnotic responsivity, the Phenomenology of Consciousness Inventory: Hypnotic Assessment Procedure (PCI-HAP). Ninety-five participants completed an Italian translation of the PCI-HAP, with srHD scores predicted from the PCI-HAP assessment items. The regression analysis replicated the previous research results. Additionally, stepwise regression analyses were able to predict the srHD score equally well using only the PCI dimension scores. These results not only replicated prior research but suggest how this methodology to assess hypnotic responsivity, when combined with more traditional neurophysiological and cognitive-behavioral methodologies, may allow for a more comprehensive understanding of that enigma called hypnosis.

Biomedical application of wavelets: analysis of electroencephalograph signals for monitoring depth of anesthesia

NASA Astrophysics Data System (ADS)

Abbate, Agostino; Nayak, A.; Koay, J.; Roy, R. J.; Das, Pankaj K.

1996-03-01

The wavelet transform (WT) has been used to study the nonstationary information in the electroencephalograph (EEG) as an aid in determining the anesthetic depth. A complex analytic mother wavelet is utilized to obtain the time evolution of the various spectral components of the EEG signal. The technique is utilized for the detection and spectral analysis of transient and background processes in the awake and asleep states. It can be observed that the response of both states before the application of the stimulus is similar in amplitude but not in spectral contents, which suggests a background activity of the brain. The brain reacts to the external stimulus in two different modes depending on the state of consciousness of the subject. In the case of awake state, there is an evident increase in response, while for the sleep state a reduction in this activity is observed. This analysis seems to suggest that the brain has an ongoing background process that monitors external stimulus in both the sleep and awake states.

Age-Related Differences in Dynamic Interactions Among Default Mode, Frontoparietal Control, and Dorsal Attention Networks during Resting-State and Interference Resolution.

PubMed

Avelar-Pereira, Bárbara; Bäckman, Lars; Wåhlin, Anders; Nyberg, Lars; Salami, Alireza

2017-01-01

Resting-state fMRI (rs-fMRI) can identify large-scale brain networks, including the default mode (DMN), frontoparietal control (FPN) and dorsal attention (DAN) networks. Interactions among these networks are critical for supporting complex cognitive functions, yet the way in which they are modulated across states is not well understood. Moreover, it remains unclear whether these interactions are similarly affected in aging regardless of cognitive state. In this study, we investigated age-related differences in functional interactions among the DMN, FPN and DAN during rest and the Multi-Source Interference task (MSIT). Networks were identified using independent component analysis (ICA), and functional connectivity was measured during rest and task. We found that the FPN was more coupled with the DMN during rest and with the DAN during the MSIT. The degree of FPN-DMN connectivity was lower in older compared to younger adults, whereas no age-related differences were observed in FPN-DAN connectivity in either state. This suggests that dynamic interactions of the FPN are stable across cognitive states. The DMN and DAN were anti correlated and age-sensitive during the MSIT only, indicating variation in a task-dependent manner. Increased levels of anticorrelation from rest to task also predicted successful interference resolution. Additional analyses revealed that the degree of DMN-DAN anticorrelation during the MSIT was associated to resting cerebral blood flow (CBF) within the DMN. This suggests that reduced DMN neural activity during rest underlies an impaired ability to achieve higher levels of anticorrelation during a task. Taken together, our results suggest that only parts of age-related differences in connectivity are uncovered at rest and thus, should be studied in the functional connectome across multiple states for a more comprehensive picture.

Age-Related Differences in Dynamic Interactions Among Default Mode, Frontoparietal Control, and Dorsal Attention Networks during Resting-State and Interference Resolution

PubMed Central

Avelar-Pereira, Bárbara; Bäckman, Lars; Wåhlin, Anders; Nyberg, Lars; Salami, Alireza

2017-01-01

Resting-state fMRI (rs-fMRI) can identify large-scale brain networks, including the default mode (DMN), frontoparietal control (FPN) and dorsal attention (DAN) networks. Interactions among these networks are critical for supporting complex cognitive functions, yet the way in which they are modulated across states is not well understood. Moreover, it remains unclear whether these interactions are similarly affected in aging regardless of cognitive state. In this study, we investigated age-related differences in functional interactions among the DMN, FPN and DAN during rest and the Multi-Source Interference task (MSIT). Networks were identified using independent component analysis (ICA), and functional connectivity was measured during rest and task. We found that the FPN was more coupled with the DMN during rest and with the DAN during the MSIT. The degree of FPN-DMN connectivity was lower in older compared to younger adults, whereas no age-related differences were observed in FPN-DAN connectivity in either state. This suggests that dynamic interactions of the FPN are stable across cognitive states. The DMN and DAN were anti correlated and age-sensitive during the MSIT only, indicating variation in a task-dependent manner. Increased levels of anticorrelation from rest to task also predicted successful interference resolution. Additional analyses revealed that the degree of DMN-DAN anticorrelation during the MSIT was associated to resting cerebral blood flow (CBF) within the DMN. This suggests that reduced DMN neural activity during rest underlies an impaired ability to achieve higher levels of anticorrelation during a task. Taken together, our results suggest that only parts of age-related differences in connectivity are uncovered at rest and thus, should be studied in the functional connectome across multiple states for a more comprehensive picture. PMID:28588476

Dynamic connectivity states estimated from resting fMRI Identify differences among Schizophrenia, bipolar disorder, and healthy control subjects.

PubMed

Rashid, Barnaly; Damaraju, Eswar; Pearlson, Godfrey D; Calhoun, Vince D

2014-01-01

Schizophrenia (SZ) and bipolar disorder (BP) share significant overlap in clinical symptoms, brain characteristics, and risk genes, and both are associated with dysconnectivity among large-scale brain networks. Resting state functional magnetic resonance imaging (rsfMRI) data facilitates studying macroscopic connectivity among distant brain regions. Standard approaches to identifying such connectivity include seed-based correlation and data-driven clustering methods such as independent component analysis (ICA) but typically focus on average connectivity. In this study, we utilize ICA on rsfMRI data to obtain intrinsic connectivity networks (ICNs) in cohorts of healthy controls (HCs) and age matched SZ and BP patients. Subsequently, we investigated difference in functional network connectivity, defined as pairwise correlations among the timecourses of ICNs, between HCs and patients. We quantified differences in both static (average) and dynamic (windowed) connectivity during the entire scan duration. Disease-specific differences were identified in connectivity within different dynamic states. Notably, results suggest that patients make fewer transitions to some states (states 1, 2, and 4) compared to HCs, with most such differences confined to a single state. SZ patients showed more differences from healthy subjects than did bipolars, including both hyper and hypo connectivity in one common connectivity state (dynamic state 3). Also group differences between SZ and bipolar patients were identified in patterns (states) of connectivity involving the frontal (dynamic state 1) and frontal-parietal regions (dynamic state 3). Our results provide new information about these illnesses and strongly suggest that state-based analyses are critical to avoid averaging together important factors that can help distinguish these clinical groups.

The relation of trait and state mindfulness with satisfaction and physical activity: A cross-sectional study in 305 Dutch participants.

PubMed

Tsafou, Kalliopi-Eleni; Lacroix, Joyca Pw; van Ee, Raymond; Vinkers, Charlotte Dw; De Ridder, Denise Td

2017-09-01

Previous research has shown that satisfaction mediates the relationship of state mindfulness (i.e. during physical activity) with physical activity. This study aimed to replicate this finding and to explore the role of trait mindfulness with a cross-sectional design. In all, 305 participants completed measures on trait and state mindfulness, satisfaction with physical activity, and physical activity. Mediation analyses were used. Satisfaction mediated the effect of state mindfulness on physical activity. Trait mindfulness related to physical activity via an indirect path, namely through two consecutive mediators, first state mindfulness and then satisfaction. Our results suggest that to enhance satisfaction, both state and trait mindfulness should be considered.

An Exploratory Study of Advancing Mobilization in the Life Insurance Industry: The Case of Taiwan's Nan Shan Life Insurance Corporation.

ERIC Educational Resources Information Center

Luarn, Pin; Lin, Tom M. Y.; Lo, Peter K. Y.

2003-01-01

Employs a case study method, using in-depth interviews of 29 corporate managers and experts, to understand the current state of mobilization in the life insurance industry. Suggests a conceptual framework and formulates possible research propositions incorporating several variables. Suggests 10 key success factors for implementing mobilization in…

Experimental study of isomeric intruder 1 2 + states in At 197 , 203

DOE PAGES

Auranen, K.; Uusitalo, J.; Juutinen, S.; ...

2017-04-10

A newly observed isomeric intruder ½ + state [T ½=3.5(6)ms] is identified in 203At using a gas-filled recoil separator and fusion-evaporation reactions. The isomer is depopulated through a cascade of E3 and mixed M1/E2 transitions to the 9/2 – ground state, and it is suggested to originate from the π(s ½) –1 configuration. In addition, the structures above the ½ + state in 203At and 197At are studied using in-beam γ-ray spectroscopy, recoil-decay tagging, and recoil-isomer decay tagging methods. As a result, the ½ + state is fed from 3/2 + and 5/2 + states, and the origin of thesemore » states are discussed.« less

Is the clinicopathological pattern of colorectal carcinoma similar in the state and private healthcare systems of South Africa? Analysis of a Durban colorectal cancer database.

PubMed

Ntombela, Xolani H; Zulu, Babongile Mw; Masenya, Molikane; Sartorius, Ben; Madiba, Thandinkosi E

2017-10-01

Previous state hospital-based local studies suggest varying population-based clinicopathological patterns of colorectal cancer (CRC). Patients diagnosed with CRC in the state and private sector hospitals in Durban, South Africa over a 12-month period (January-December 2009) form the basis of our study. Of 491 patients (172 state and 319 private sector patients), 258 were men. State patients were younger than private patients. Anatomical site distribution was similar in both groups with minor variations. Stage IV disease was more common in state patients. State patients were younger, presented with advanced disease and had a lower resection rate. Black patients were the youngest, presented with advanced disease and had the lowest resection rate.

How states of mind change in psychotherapy: an intensive case analysis of Lisa's case using the Grid of Problematic States.

PubMed

Nicolo, Giuseppe; Dimaggio, Giancarlo; Procacci, Michele; Semerari, Antonio; Carcione, Antonino; Pedone, Roberto

2008-11-01

This study uses the Grid of Problematic States (GPS) to examine Lisa's case, one of the most successful in the York Psychotherapy Depression Project. This study tried to assess whether the contents of mental experience form stable clusters consistent with a diagnosis of depression. It was possible with the GPS to pinpoint problematic states typical of depression and trace the transitional states occurring in Lisa between two different mental states: depressive and well-being. The GPS analysis suggested that the treatment successfully managed to deal with symptoms and to change the patient's thought themes and emotions. At the end of treatment, Lisa was less sad and displayed some anger, and a state of being nurtured emerged.

The modulation of EEG variability between internally- and externally-driven cognitive states varies with maturation and task performance

PubMed Central

Willatt, Stephanie E.; Cortese, Filomeno; Protzner, Andrea B.

2017-01-01

Increasing evidence suggests that brain signal variability is an important measure of brain function reflecting information processing capacity and functional integrity. In this study, we examined how maturation from childhood to adulthood affects the magnitude and spatial extent of state-to-state transitions in brain signal variability, and how this relates to cognitive performance. We looked at variability changes between resting-state and task (a symbol-matching task with three levels of difficulty), and within trial (fixation, post-stimulus, and post-response). We calculated variability with multiscale entropy (MSE), and additionally examined spectral power density (SPD) from electroencephalography (EEG) in children aged 8–14, and in adults aged 18–33. Our results suggest that maturation is characterized by increased local information processing (higher MSE at fine temporal scales) and decreased long-range interactions with other neural populations (lower MSE at coarse temporal scales). Children show MSE changes that are similar in magnitude, but greater in spatial extent when transitioning between internally- and externally-driven brain states. Additionally, we found that in children, greater changes in task difficulty were associated with greater magnitude of modulation in MSE. Our results suggest that the interplay between maturational and state-to-state changes in brain signal variability manifest across different spatial and temporal scales, and influence information processing capacity in the brain. PMID:28750035

Sport Psychology.

ERIC Educational Resources Information Center

Krotee, March L.

1980-01-01

Sport psychology is defined in terms of human behavior in athletic situations. The psychosocial cross-cultural setting provides a model for studying trait and state psychosocial attributes and suggests issues and concerns for further study. (JMF)

The Florida State Initial Teacher Certification Test: A Case Study.

ERIC Educational Resources Information Center

Dorn, Charles M.

1989-01-01

Describes the development of the art certification examination which was designed for the Florida State Initial Teacher Certification Test. Discusses problems of subjectivity, content, and question format. Suggests criteria which can guide the development of viable college art education programs that can adequately prepare teachers in the areas of…

Checkpoint A-French. Course of Study in Foreign Languages.

ERIC Educational Resources Information Center

New York City Board of Education, Brooklyn, NY. Div. of Curriculum and Instruction.

The New York City schools' syllabus for the first year of high school French instruction outlines a communicative curriculum conforming to state standards of preparation for state language proficiency examinations. The syllabus begins with an introductory section that describes the objectives and approach used and provides suggestions for…

Performance Funding in Higher Education: Do Financial Incentives Impact College Completions?

ERIC Educational Resources Information Center

Hillman, Nicholas W.; Tandberg, David A.; Gross, Jacob P. K.

2014-01-01

In 2000, the Pennsylvania State System of Higher Education introduced a performance-based funding model aimed at increasing degree productivity among the state's public colleges. This study examines how the new policy affected undergraduate degree completions. Using a difference-in-differences estimation strategy, results suggest the policy has…

Puerto Rican Return Migrant Youth.

ERIC Educational Resources Information Center

Carrasquillo, Angela; Carrasquillo, Ceferino

Among Puerto Ricans who have migrated to the United States, a significant number have returned to Puerto Rico, while others shuttle between Puerto Rico and the United States. These groups of people are identified as return migrants. Studies suggest that return migrant youth in Puerto Rico have had to make environmental and cultural adjustments…

Alcohol Impairment and Social Drinking.

ERIC Educational Resources Information Center

Bates, Marsha E.

Cognitive abilities of social drinkers are generally thought to be affected by alcohol only during acute intoxication, but several studies suggest that sober-state performance may be affected by the quantity of alcohol consumed per drinking episode. Although the findings regarding sober-state mental deficits in social drinkers are inconclusive,…

Single-molecule chemo-mechanical unfolding reveals multiple transition state barriers in a small single-domain protein

NASA Astrophysics Data System (ADS)

Guinn, Emily J.; Jagannathan, Bharat; Marqusee, Susan

2015-04-01

A fundamental question in protein folding is whether proteins fold through one or multiple trajectories. While most experiments indicate a single pathway, simulations suggest proteins can fold through many parallel pathways. Here, we use a combination of chemical denaturant, mechanical force and site-directed mutations to demonstrate the presence of multiple unfolding pathways in a simple, two-state folding protein. We show that these multiple pathways have structurally different transition states, and that seemingly small changes in protein sequence and environment can strongly modulate the flux between the pathways. These results suggest that in vivo, the crowded cellular environment could strongly influence the mechanisms of protein folding and unfolding. Our study resolves the apparent dichotomy between experimental and theoretical studies, and highlights the advantage of using a multipronged approach to reveal the complexities of a protein's free-energy landscape.

Emotional intelligence and personality in major depression: trait versus state effects.

PubMed

Hansenne, Michel; Bianchi, Julien

2009-03-31

Several studies have explored the link between depression and personality with classical personality questionnaires like the Revised NEO Personality Inventory and the Temperament and Character Inventory (TCI). However, no studies have been conducted with the revised form of the TCI (TCI-R). Moreover, since a few studies conducted on normal subjects suggest that Emotional Intelligence (EI) would be lower in depression, but that the concept has not been explicitly measured in patients with major depressive disorder, EI was assessed here with the modified version of Schutte's scale among a group of depressive patients. In addition, both personality and EI measures were carried out during the clinical state of depression and after the remission to assess the state versus trait aspect. The study was conducted on 54 major depressive inpatients (20 in remission) and 54 matched controls. As expected, depressive patients exhibited higher score on harm avoidance (HA), and lower scores on persistence (P), self-directedness (SD), cooperativeness (C), optimism/emotional regulation subscore, and total EI score as compared with controls. In the period of remission, patients again had elevated scores on HA, and lower scores on SD. In contrast, the total EI score did not differ between controls and depressive patients in remission. The results confirm that some personality dimensions are dependent on both state and trait aspects of depression, and suggest that EI only seems to be affected during the clinical state.

Unconventional iron-based superconductor CsCa2Fe4As4F2: A first-principle study

NASA Astrophysics Data System (ADS)

Singh, Birender; Kumar, Pradeep

2018-05-01

In the present work, we have investigated the structural and electronic properties of newly discovered iron based superconductor CsCa2Fe4As4F2 using first principles calculations. Analysis of the density of states at the Fermi level suggests that Fe-3d states have dominating contribution, and within these 3d states contribution of eg states is significant suggesting multi-band nature of this superconductor. The upper bound of superconducting transition temperature, estimated using electron-phonon coupling constant is found to be ˜2.6 K. To produce the experimental value of transition temperature (28.2 K), a 4-5 times increase in the electron-phonon constant is necessary, hinting that conventional electron-phonon coupling is not enough to explain the origin of superconductivity.

Revisiting Arieti's “Listening Attitude” and Hallucinated Voices

PubMed Central

Hoffman, Ralph E.

2010-01-01

Silvano Arieti proposed that auditory/verbal hallucinations (AVHs) are triggered by momentary states of heightened auditory attention that he identified as a “listening attitude.” Studies and clinical observations by our group support this view. Patients enrolled in our repetitive transcranial magnetic stimulation trials, if experiencing a significant curtailment of these hallucinations, often report an episodic sense that their voices are still occurring even if they no longer can be heard, suggesting episodic states of heightened auditory expectancy. Moreover, a functional magnetic resonance study reported by our group detected activation in the left insula prior to hallucination events. This finding is suggestive of activation in the same region detected in healthy subjects during “auditory search” in response to ambiguous sounds when anticipating meaningful speech. AVHs often are experienced with a deep emotional salience and may occur in the context of dramatic social isolation that together could reinforce heightened auditory expectancy. These findings and clinical observations suggest that Arieti's original formulation deserves further study. PMID:20363873

Consumer hypnotic-like suggestibility: possible mechanism in compulsive purchasing.

PubMed

Prete, M Irene; Guido, Gianluigi; Pichierri, Marco

2013-08-01

The authors hypothesize a concept, Consumer Hypnotic-Like Suggestibility (CHLS), defined as an altered state of consciousness, as a state causing a tendency to respond positively to messages aimed at inducing consumers to make unplanned purchases. This study aims to investigate the associations of CHLS with interpersonal variables and compulsive purchasing--a frequent and uncontrollable preoccupation with buying or impulses to buy. A study was conducted on a sample of 232 subjects (n = 111 men; M age = 41 yr.), through the administration of a questionnaire, which measured: CHLS, compulsive purchasing, consumer susceptibility to interpersonal influence (the necessity to enhance one's image in the opinion of others through the consumption of products), and consumer atmospherics, i.e., environmental stimuli known to influence purchasing decisions. Modeling and mediation analyses suggested that internal and external drivers--Consumer Susceptibility to Interpersonal Influence and atmospherics--are positively related to CHLS which affects compulsive purchasing.

Nuclear Structure Studies of 44S and 26Si

NASA Astrophysics Data System (ADS)

Parker, John J., IV

Experimental results on the nuclear structure of 44 S and 26Si will be reported in this thesis. 44S is studied because of its interest in understanding how nuclei behave far from stability. 26Si is studied because of the impact of understanding its nuclear structure can have on the astrophysical 25Al(p,gamma) reaction rate. These are two very differently motivated studies and will be described separately in Chapters 2 and 3, respectively. Chapter 2 focuses on the exotic N=28 nucleus, in 44S. Previous experiments observed a 4+ state and suggested that this state may exhibit a hindered E2-decay rate, inconsistent with being a member of the collective ground state band. We populate this state via a two-proton knockout reaction from a beam of exotic 46Ar projectiles delivered from the coupled cyclotron facility and measure its lifetime using the recoil distance method with the GRETINA gamma ray spectrometer. The result, 76(14) stat(20)syst ps, implies a hindered transition of B(E2; 4+ →2+1 ) = 0.61(19) single- particle or Weisskopf units strength and supports the interpretation of the 4+ state as a K = 4 isomer, the first example of a high-K isomer in a nucleus of such low mass. Chapter 3 focuses on resonances above the proton threshold in 26Si. Previous experiments have solidified the placement of 3 resonances thought to contribute to the 25Al(p,gamma)26Si reaction. A fourth resonance has been suggested by various experiments, but more recent experiments have suggested that this level has been misidentified. We populate excited states in 26Si via the 24Mg( 3He,n) reaction at 10 MeV at the John Fox Lab at FSU. Neutron time-of-flight spectroscopy is used to identify which resonance is populated in 26 Si and the gamma-array at FSU is used to determine how these levels de-excite. The gamma ray sensitivity in this experiment is the highest sensitivity reached to date, but a 4th resonance above the proton threshold was not identified, giving further indication that this state may have been misidentified by past experiments.

Literature Circles in a Fifth Grade Classroom: A Qualitative Study Examining How the Teacher and Students Used Literature Circles and the Impact They Have on Student Learning

ERIC Educational Resources Information Center

Pambianchi, Laura Claypool

2017-01-01

State and national standards, including the Common Core State Standards, state that students should be expected to learn to discuss and analyze texts, comprehend ideas in increasingly complex texts, and justify their thinking. Literature circles are an instructional practice suggested by many educational writers as an instructional practice that…

Dynamical origin of non-thermal states in galactic filaments

NASA Astrophysics Data System (ADS)

Di Cintio, Pierfrancesco; Gupta, Shamik; Casetti, Lapo

2018-03-01

Observations strongly suggest that filaments in galactic molecular clouds are in a non-thermal state. As a simple model of a filament, we study a two-dimensional system of self-gravitating point particles by means of numerical simulations of the dynamics, with various methods: direct N-body integration of the equations of motion, particle-in-cell simulations, and a recently developed numerical scheme that includes multiparticle collisions in a particle-in-cell approach. Studying the collapse of Gaussian overdensities, we find that after the damping of virial oscillations the system settles in a non-thermal steady state whose radial density profile is similar to the observed ones, thus suggesting a dynamical origin of the non-thermal states observed in real filaments. Moreover, for sufficiently cold collapses, the density profiles are anticorrelated with the kinetic temperature, i.e. exhibit temperature inversion, again a feature that has been found in some observations of filaments. The same happens in the state reached after a strong perturbation of an initially isothermal cylinder. Finally, we discuss our results in the light of recent findings in other contexts (including non-astrophysical ones) and argue that the same kind of non-thermal states may be observed in any physical system with long-range interactions.

Two Salt Bridges Differentially Contribute to the Maintenance of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channel Function*

PubMed Central

Cui, Guiying; Freeman, Cody S.; Knotts, Taylor; Prince, Chengyu Z.; Kuang, Christopher; McCarty, Nael A.

2013-01-01

Previous studies have identified two salt bridges in human CFTR chloride ion channels, Arg352-Asp993 and Arg347-Asp924, that are required for normal channel function. In the present study, we determined how the two salt bridges cooperate to maintain the open pore architecture of CFTR. Our data suggest that Arg347 not only interacts with Asp924 but also interacts with Asp993. The tripartite interaction Arg347-Asp924-Asp993 mainly contributes to maintaining a stable s2 open subconductance state. The Arg352-Asp993 salt bridge, in contrast, is involved in stabilizing both the s2 and full (f) open conductance states, with the main contribution being to the f state. The s1 subconductance state does not require either salt bridge. In confirmation of the role of Arg352 and Asp993, channels bearing cysteines at these sites could be latched into a full open state using the bifunctional cross-linker 1,2-ethanediyl bismethanethiosulfonate, but only when applied in the open state. Channels remained latched open even after washout of ATP. The results suggest that these interacting residues contribute differently to stabilizing the open pore in different phases of the gating cycle. PMID:23709221

Whole genome sequencing and phylogenetic analysis of Bluetongue virus serotype 2 strains isolated in the Americas including a novel strain from the western United States.

PubMed

Gaudreault, Natasha N; Mayo, Christie E; Jasperson, Dane C; Crossley, Beate M; Breitmeyer, Richard E; Johnson, Donna J; Ostlund, Eileen N; MacLachlan, N James; Wilson, William C

2014-07-01

Bluetongue is a potentially fatal arboviral disease of domestic and wild ruminants that is characterized by widespread edema and tissue necrosis. Bluetongue virus (BTV) serotypes 10, 11, 13, and 17 occur throughout much of the United States, whereas serotype 2 (BTV-2) was previously only detected in the southeastern United States. Since 1998, 10 other BTV serotypes have also been isolated from ruminants in the southeastern United States. In 2010, BTV-2 was identified in California for the first time, and preliminary sequence analysis indicated that the virus isolate was closely related to BTV strains circulating in the southeastern United States. In the current study, the whole genome sequence of the California strain of BTV-2 was compared with those of other BTV-2 strains in the Americas. The results of the analysis suggest co-circulation of genetically distinct viruses in the southeastern United States, and further suggest that the 2010 western isolate is closely related to southeastern strains of BTV. Although it remains uncertain as to how this novel virus was translocated to California, the findings of the current study underscore the need for ongoing surveillance of this economically important livestock disease.

A comparative study of population health in the United States and Canada during the neoliberal era, 1980-2008.

PubMed

Siddiqi, Arjumand; Kawachi, Ichiro; Keating, Daniel P; Hertzman, Clyde

2013-01-01

This article draws on the vast evidence that suggests, on one hand, that socioeconomic inequalities in health are present in every society in which they have been measured and, on the other hand, that the size of inequalities varies substantially across societies. We conduct a comparative case study of the United States and Canada to explore the role of neoliberalism as a force that has created inequalities in socioeconomic resources (and thus in health) in both societies and the roles of other societal forces (political, economic, and social) that have provided a buffer, thereby lessening socioeconomic inequalities or their effects on health. Our findings suggest that, from 1980 to 2008, while both the United States and Canada underwent significant neoliberal reforms, Canada showed more resilience in terms of health inequalities as a result of differences in: (a) the degree of income inequality, itself resulting from differences in features of the labor market and tax and transfer policies, (b) equality in the provision of social goods such as health care and education, and (c) the extent of social cohesiveness across race/ethnic- and class-based groups. Our study suggests that further attention must be given to both causes and buffers of health inequalities.

Feedback: Implications for Further Research and Study.

ERIC Educational Resources Information Center

Nishikawa, Sue S.

This report reviews current literature on feedback and suggests practical implications of feedback research for educators. A definition of feedback is offered, and past definitions in prior research are noted. An analysis of the current state of knowledge of feedback discusses the historical development of feedback theory and suggests that…

Contributions of diverse excitatory and inhibitory neurons to recurrent network activity in cerebral cortex.

PubMed

Neske, Garrett T; Patrick, Saundra L; Connors, Barry W

2015-01-21

The recurrent synaptic architecture of neocortex allows for self-generated network activity. One form of such activity is the Up state, in which neurons transiently receive barrages of excitatory and inhibitory synaptic inputs that depolarize many neurons to spike threshold before returning to a relatively quiescent Down state. The extent to which different cell types participate in Up states is still unclear. Inhibitory interneurons have particularly diverse intrinsic properties and synaptic connections with the local network, suggesting that different interneurons might play different roles in activated network states. We have studied the firing, subthreshold behavior, and synaptic conductances of identified cell types during Up and Down states in layers 5 and 2/3 in mouse barrel cortex in vitro. We recorded from pyramidal cells and interneurons expressing parvalbumin (PV), somatostatin (SOM), vasoactive intestinal peptide (VIP), or neuropeptide Y. PV cells were the most active interneuron subtype during the Up state, yet the other subtypes also received substantial synaptic conductances and often generated spikes. In all cell types except PV cells, the beginning of the Up state was dominated by synaptic inhibition, which decreased thereafter; excitation was more persistent, suggesting that inhibition is not the dominant force in terminating Up states. Compared with barrel cortex, SOM and VIP cells were much less active in entorhinal cortex during Up states. Our results provide a measure of functional connectivity of various neuron types in barrel cortex and suggest differential roles for interneuron types in the generation and control of persistent network activity. Copyright © 2015 the authors 0270-6474/15/351089-17$15.00/0.

State-dependent sensorimotor processing: gaze and posture stability during simulated flight in birds.

PubMed

McArthur, Kimberly L; Dickman, J David

2011-04-01

Vestibular responses play an important role in maintaining gaze and posture stability during rotational motion. Previous studies suggest that these responses are state dependent, their expression varying with the environmental and locomotor conditions of the animal. In this study, we simulated an ethologically relevant state in the laboratory to study state-dependent vestibular responses in birds. We used frontal airflow to simulate gliding flight and measured pigeons' eye, head, and tail responses to rotational motion in darkness, under both head-fixed and head-free conditions. We show that both eye and head response gains are significantly higher during flight, thus enhancing gaze and head-in-space stability. We also characterize state-specific tail responses to pitch and roll rotation that would help to maintain body-in-space orientation during flight. These results demonstrate that vestibular sensorimotor processing is not fixed but depends instead on the animal's behavioral state.

State-dependent sensorimotor processing: gaze and posture stability during simulated flight in birds

PubMed Central

McArthur, Kimberly L.

2011-01-01

Vestibular responses play an important role in maintaining gaze and posture stability during rotational motion. Previous studies suggest that these responses are state dependent, their expression varying with the environmental and locomotor conditions of the animal. In this study, we simulated an ethologically relevant state in the laboratory to study state-dependent vestibular responses in birds. We used frontal airflow to simulate gliding flight and measured pigeons′ eye, head, and tail responses to rotational motion in darkness, under both head-fixed and head-free conditions. We show that both eye and head response gains are significantly higher during flight, thus enhancing gaze and head-in-space stability. We also characterize state-specific tail responses to pitch and roll rotation that would help to maintain body-in-space orientation during flight. These results demonstrate that vestibular sensorimotor processing is not fixed but depends instead on the animal's behavioral state. PMID:21307332

Theoretical Study of Tautomerization Reactions for the Ground and First Excited Electronic States of Adenine

NASA Technical Reports Server (NTRS)

Salter, Latasha M.; Chaban, Galina M.; Kwak, Dochan (Technical Monitor)

2002-01-01

Geometrical structures and energetic properties for different tautomers of adenine are calculated in this study, using multi-configurational wave functions. Both the ground and the lowest singlet excited state potential energy surfaces are studied. Four tautomeric forms are considered, and their energetic order is found to be different on the ground and the excited state potential energy surfaces. Minimum energy reaction paths are obtained for hydrogen atom transfer (tautomerization) reactions in the ground and the lowest excited electronic states. It is found that the barrier heights and the shapes of the reaction paths are different for the ground and the excited electronic states, suggesting that the probability of such tautomerization reaction is higher on the excited state potential energy surface. This tautomerization process should become possible in the presence of water or other polar solvent molecules and should play an important role in the photochemistry of adenine.

Dynamics of the GB3 loop regions from MD simulation: how much of it is real?

PubMed

Li, Tong; Jing, Qingqing; Yao, Lishan

2011-04-07

A total of 1.1 μs of molecular dynamics (MD) simulations were performed to study the structure and dynamics of protein GB3. The simulation motional amplitude of the loop regions is generally overestimated in comparison with the experimental backbone N-H order parameters S(2). Two-state behavior is observed for several residues in these regions, with the minor state population in the range of 3-13%. Further inspection suggests that the (φ, ψ) dihedral angles of the minor states deviate from the GB3 experimental values, implying the existence of nonnative states. After fitting the MD trajectories of these residues to the NMR RDCs, the minor state populations are significantly reduced by at least 80%, suggesting that MD simulations are strongly biased toward the minor states, thus overestimating the dynamics of the loop regions. The optimized trajectories produce intra, sequential H(N)-H(α) RDCs and intra (3)J(HNHα) that are not included in the trajectories fitting for these residues that are closer to the experimental data. Unlike GB3, 0.55 μs MD simulations of protein ubiquitin do not show distinctive minor states, and the derived NMR order parameters are better converged. Our findings indicate that the artifacts of the simulations depend on the specific system studied and that one should be cautious interpreting the enhanced dihedral dynamics from long MD simulations.

Elder abuse awareness and action: the role of state summits.

PubMed

Anetzberger, Georgia J; Balaswamy, Shantha

2010-01-01

Increasingly, states are convening summits to identify appropriate local responses to elder abuse. This first-ever nationwide research on state-level elder abuse summits examines what leads to their formation, what they accomplish, and what factors contribute to their success. Study results suggest that two-fifths of the states have held summits, four-fifths of which have been since 2000. Typically the summits were convened by the state department of human services or aging, involved 25-50 participants, and lasted less than 2 years. Nearly 50% of study respondents felt that summit goals had been met, and 60% stated that recommendations were implemented, usually because of committed participants, involvement of the right people, or strong advocacy. State summits can be effective means for galvanizing collective action to address elder abuse as a complex social problem.

The Idea of the College in Western Postsecondary Education: A Study in Adaptation from an Historical and Comparative Perspective. France, Germany, England, and the United States.

ERIC Educational Resources Information Center

Pfnister, Allan O.

The idea of the college as a residential and instructional entity preparing students for advanced study by establishing basic knowledge in the liberal arts has a long history in Europe and the United States. The German term "Bildung" describes this function well, with its suggestions of "knowledge, culture, the power of expression,…

Somatic influences on subjective well-being and affective disorders: the convergence of thermosensory and central serotonergic systems

PubMed Central

Raison, Charles L.; Hale, Matthew W.; Williams, Lawrence E.; Wager, Tor D.; Lowry, Christopher A.

2015-01-01

Current theories suggest that the brain is the sole source of mental illness. However, affective disorders, and major depressive disorder (MDD) in particular, may be better conceptualized as brain-body disorders that involve peripheral systems as well. This perspective emphasizes the embodied, multifaceted physiology of well-being, and suggests that afferent signals from the body may contribute to cognitive and emotional states. In this review, we focus on evidence from preclinical and clinical studies suggesting that afferent thermosensory signals contribute to well-being and depression. Although thermoregulatory systems have traditionally been conceptualized as serving primarily homeostatic functions, increasing evidence suggests neural pathways responsible for regulating body temperature may be linked more closely with emotional states than previously recognized, an affective warmth hypothesis. Human studies indicate that increasing physical warmth activates brain circuits associated with cognitive and affective functions, promotes interpersonal warmth and prosocial behavior, and has antidepressant effects. Consistent with these effects, preclinical studies in rodents demonstrate that physical warmth activates brain serotonergic neurons implicated in antidepressant-like effects. Together, these studies suggest that (1) thermosensory pathways interact with brain systems that control affective function, (2) these pathways are dysregulated in affective disorders, and (3) activating warm thermosensory pathways promotes a sense of well-being and has therapeutic potential in the treatment of affective disorders. PMID:25628593

Projected Entangled Pair States with non-Abelian gauge symmetries: An SU(2) study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zohar, Erez, E-mail: erez.zohar@mpq.mpg.de; Wahl, Thorsten B.; Burrello, Michele, E-mail: michele.burrello@mpq.mpg.de

Over the last years, Projected Entangled Pair States have demonstrated great power for the study of many body systems, as they naturally describe ground states of gapped many body Hamiltonians, and suggest a constructive way to encode and classify their symmetries. The PEPS study is not only limited to global symmetries, but has also been extended and applied for local symmetries, allowing to use them for the description of states in lattice gauge theories. In this paper we discuss PEPS with a local, SU(2) gauge symmetry, and demonstrate the use of PEPS features and techniques for the study of amore » simple family of many body states with a non-Abelian gauge symmetry. We present, in particular, the construction of fermionic PEPS able to describe both two-color fermionic matter and the degrees of freedom of an SU(2) gauge field with a suitable truncation.« less

From franchise to state commission: Regulation of the electric utility industry, 1907 to 1932

NASA Astrophysics Data System (ADS)

Reutter, Keith Alan

1997-09-01

Empirical research into the effects of regulation on industry has been around since the early 1960s. Over the last thirty plus years a number of interesting results have been brought to the fore. For instance, it has been found that regulation of the trucking industry limits entry and increases prices. A similar result has been pointed to in other industries such as commercial airlines and banking. The effect of the state commission form of regulation on the electric utility industry has been less conclusive. State commissions became dominant during the period 1910-1930, replacing local franchising as a method of regulating the electric utility industry. Two competing theories suggest why this transformation took place, the "capture" and "public interest" theories of regulation. The capture theory of regulation suggests that the electric utility industry demanded state regulation as a way to earn above normal profits and reduce competition. The public interest theory suggests the purpose of regulation by state commissions was to benefit the general public by forcing the industry to be competitive. Few studies have tried to determine which theory more aptly describes the actual events that took place. The empirical model developed in Chapter V, is an extension of the current literature. A set of simultaneous equations describing the natural gas and electricity markets is estimated using cross-sectional time-series data from 1907 to 1932. The effect of regulation on the electric utility industry is modeled with a dummy variable taking on a value of one to designate that a state commission had been established. The results suggest the capture theory of regulation best describes the period under study. The empirical estimates indicate that state commissions (1) reduced the rate at which the real price of electricity was falling, (2) had a negative impact on firms entering the industry, (3) had a positive influence on the cost of producing a kwh of electricity, and (4) prevented industry profits from declining. This research adds to the existing literature on industry regulation in general, and specifically to the literature on the effects of regulation of the electric utility industry.

University Library Development in the Arab Gulf Region: A Survey and Analysis of Six State University Libraries.

ERIC Educational Resources Information Center

Zehery, Mohamed H.

1997-01-01

This study of state university libraries in Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates provides information on library organization and analysis of collections, services, staffing, budgeting, expenditures, automation, and information technology. Suggests further research is needed in collections, services and…

The Mississippi Choctaw: A Case Study of Intercultural Games.

ERIC Educational Resources Information Center

Hill, L. Brooks; Lujan, Philip

1983-01-01

Examines the Smith John case--in which the United States Supreme Court secured official recognition of the Mississippi Band of Choctaw as a tribe--as an example of "rhetorical games" used by different cultural groups to manipulate each other. Suggests alternative rhetorical strategies that would benefit the state and the Mississippi…

International Graduate Student Mobility in the US: What More Can We Be Doing?

ERIC Educational Resources Information Center

Roberts, Darbi L.

2012-01-01

This article examines the current growth statistics of international graduate student populations in the United States in order to present trends in international student mobility. Although many scholars suggest the United States is facing a decrease in future international student demand, recent studies seem to challenge this theory. This article…

Chemistry: Experiments, Demonstrations and Other Activities Suggested for Chemistry.

ERIC Educational Resources Information Center

New York State Education Dept., Albany. Bureau of Secondary Curriculum Development.

This publication is a handbook used in conjunction with the course of study in chemistry developed through the New York State Education Department and The University of the State of New York. It contains experiments, demonstrations, and other activities for a chemistry course. Areas covered include the science of chemistry, the atomic structure of…

AGRICULTURAL CHEMICALS TECHNOLOGY, A SUGGESTED TWO-YEAR POST HIGH SCHOOL CURRICULUM AND COURSE OUTLINES.

ERIC Educational Resources Information Center

HALTERMAN, JERRY; AND OTHERS

DATA REVEALED BY STUDIES OF AGRICULTURAL BUSINESS TRAINING NEEDS CONDUCTED IN SEVERAL STATES PROMPTED THE DESIGN OF AN INSTRUCTIONAL MATERIALS SERIES TO ASSIST STATE AND LOCAL VOCATIONAL EDUCATION LEADERS IN DEVELOPING PROGRAMS TO PREPARE YOUTH AND ADULTS FOR EMPLOYMENT AND ADVANCEMENT IN OFF-FARM AGRICULTURAL OCCUPATIONS. THIS DOCUMENT, THE…

Images for NCA's Future: Perceptions in One State.

ERIC Educational Resources Information Center

Kirkpatrick, Kathryn; Brainard, Edward

1995-01-01

Describes a study examining the attitudes of K-12 educators toward their state's North Central Association (NCA) and its future. Indicates that external peer reviews were cited as the most valuable programs, while many suggestions for the future were related to the NCA-university connection, emphasizing a dynamic role for universities serving as…

Cold hardiness of winter-acclimated Drosophila suzukii (Diptera: Drosophilidae) adults

Treesearch

A.R. Stephens; M.K. Asplen; W.D. Hutchison; Robert C. Venette

2015-01-01

Drosophila suzukii Matsumura, often called spotted wing drosophila, is an exotic vinegar fly that is native to Southeast Asia and was first detected in the continental United States in 2008. Previous modeling studies have suggested that D. suzukii might not survive in portions of the northern United States or southern Canada...

Centralized Negotiations of Salaries of Professional Staff in Education.

ERIC Educational Resources Information Center

Peterson, LeRoy J.

This document reports on a study conducted in six European countries -- Denmark, England, France, Norway, Scotland, and Sweden -- and suggests ways to implement Statewide negotiations in the United States. The author first provides an overview of negotiations in the United States and then gives a country-by-country analysis of salary negotiations.…

One Nation, Many Peoples: Immigration in the United States. A Resource Book.

ERIC Educational Resources Information Center

Pferdehirt, Julia; Schreiner, Dave; DiPrima, Liza; Kniskern, Ann

This resource book provides historical summaries, primary source documents, reproducible activities, creative project suggestions and research ideas on the study of immigration to the United States. The book is divided into eight units that correspond to eight geographic regions: East Asia, Southeast Asia, South Asia and the Middle East, Eastern…

Gubernatorial Authority and Influence on Public Higher Education

ERIC Educational Resources Information Center

Christakis, Michael N.

2009-01-01

State governors have the potential to impact their states' public higher education systems in a variety of very significant ways. The findings for the 33 governors included in this study suggest a great deal of variation in the extent of their authority and influence. Governors' composite ratings of formal authority and informal influence are…

Assessing and Cultivating Support for Strategic Planning: Searching for Best Practices in a Reform Environment

ERIC Educational Resources Information Center

Welsh, John F.; Nunez, William J.; Petrosko, Joseph

2006-01-01

This study examines the similarities and differences in faculty and administrator perspectives on strategic planning in Kentucky, a state in the United States undergoing extensive reform of its public, postsecondary system. The findings suggest that three variables are critical to faculty and administrative support for strategic planning…

Staff Recommendations Concerning the Delivery of Hepatitis-Related Services in County Health Departments

ERIC Educational Resources Information Center

Rainey, Jacquie

2007-01-01

Background: This paper describes a portion of a larger evaluation project of a state hepatitis prevention program. Purpose: The study explored the suggestions of key informants related to the delivery of hepatitis services in the state. Methods: Researchers conducted key informant interviews lasting 30 to 45 minutes. Results: Important findings…

Readability of Brochures Produced by State of Florida.

ERIC Educational Resources Information Center

Christ, William G.; Pharr, Paula

1980-01-01

A study of the readability of governmental pamphlets produced by the State of Florida, based on the use of the Flesch Reading Ease Formula and the Dale-Chall Formula, suggests that if a seventh or eighth grade readability level is considered an appropriate standard for public information brochures, the brochures tested may be too complex…

Effects of Maternal Work Incentives on Teen Drug Arrests

PubMed Central

Corman, Hope; Dave, Dhaval; Kalil, Ariel; Reichman, Nancy E.

2017-01-01

Purpose This study exploits differences in the implementation of welfare reform across states and over time in the United States in the attempt to identify causal effects of welfare reform on youth arrests for drug-related crimes between 1990 and 2005, the period during which welfare reform unfolded. Methodology Using monthly arrest data from the U.S. Federal Bureau of Investigation's Uniform Crime Reports, we estimate the effects of welfare reform implementation on drug-related arrests among 15–17 year olds in the United States between 1990 and 2005. We use a difference-in-differences (DD) approach that exploits the implementation of welfare reform across states and over time to estimate effects for teens exposed to welfare reform. Findings The findings, based on numerous different model specifications, suggest that welfare reform had no statistically significant effect on teen drug arrests. Most estimates were positive and suggestive of a small (3%) increase in arrests. Originality/Value This study investigated the effects of a broad-based policy change that altered maternal employment, family income, and other family characteristics on youth drug arrests. PMID:28989228

Bottom-up excited state dynamics of two cinnamate-based sunscreen filter molecules.

PubMed

Peperstraete, Yoann; Staniforth, Michael; Baker, Lewis A; Rodrigues, Natércia D N; Cole-Filipiak, Neil C; Quan, Wen-Dong; Stavros, Vasilios G

2016-10-12

Methyl-E-4-methoxycinnamate (E-MMC) is a model chromophore of the commonly used commercial sunscreen agent, 2-ethylhexyl-E-4-methoxycinnamate (E-EHMC). In an effort to garner a molecular-level understanding of the photoprotection mechanisms in operation with E-EHMC, we have used time-resolved pump-probe spectroscopy to explore E-MMC's and E-EHMC's excited state dynamics upon UV-B photoexcitation to the S 1 (1 1 ππ*) state in both the gas- and solution-phase. In the gas-phase, our studies suggest that the excited state dynamics are driven by non-radiative decay from the 1 1 ππ* to the S 3 (1 1 nπ*) state, followed by de-excitation from the 1 1 nπ* to the ground electronic state (S 0 ). Using both a non-polar-aprotic solvent, cyclohexane, and a polar-protic solvent, methanol, we investigated E-MMC and E-EHMC's photochemistry in a more realistic, 'closer-to-shelf' environment. A stark change to the excited state dynamics in the gas-phase is observed in the solution-phase suggesting that the dynamics are now driven by efficient E/Z isomerisation from the initially photoexcited 1 1 ππ* state to S 0 .

Resting state EEG correlates of memory consolidation.

PubMed

Brokaw, Kate; Tishler, Ward; Manceor, Stephanie; Hamilton, Kelly; Gaulden, Andrew; Parr, Elaine; Wamsley, Erin J

2016-04-01

Numerous studies demonstrate that post-training sleep benefits human memory. At the same time, emerging data suggest that other resting states may similarly facilitate consolidation. In order to identify the conditions under which non-sleep resting states benefit memory, we conducted an EEG (electroencephalographic) study of verbal memory retention across 15min of eyes-closed rest. Participants (n=26) listened to a short story and then either rested with their eyes closed, or else completed a distractor task for 15min. A delayed recall test was administered immediately following the rest period. We found, first, that quiet rest enhanced memory for the short story. Improved memory was associated with a particular EEG signature of increased slow oscillatory activity (<1Hz), in concert with reduced alpha (8-12Hz) activity. Mindwandering during the retention interval was also associated with improved memory. These observations suggest that a short period of quiet rest can facilitate memory, and that this may occur via an active process of consolidation supported by slow oscillatory EEG activity and characterized by decreased attention to the external environment. Slow oscillatory EEG rhythms are proposed to facilitate memory consolidation during sleep by promoting hippocampal-cortical communication. Our findings suggest that EEG slow oscillations could play a significant role in memory consolidation during other resting states as well. Copyright © 2016 Elsevier Inc. All rights reserved.

The relationship between the FFM personality traits, state psychopathology, and sexual compulsivity in a sample of male college students.

PubMed

Pinto, Joana; Carvalho, Joana; Nobre, Pedro J

2013-07-01

Several studies have advocated a relationship between psychopathological features and sexual compulsivity. Such relationship is often found among individuals seeking help for out of control sexual behavior, suggesting that the association between psychological adjustment and sexual compulsivity may have a significant clinical value. However, a more complete approach to the topic of sexual compulsivity would also include the analysis of nonclinical samples as healthy individuals may be at risk of developing some features of hypersexuality in the future. The aim of this study was to explore the relationship between stable traits of personality, state psychopathology, and sexual compulsivity in a sample of male college students. Furthermore, the potential mediating role of state psychopathology in the relationship between personality traits and sexual compulsivity was tested. Participants completed the following measures: the NEO Five-Factor Inventory, the Brief Symptom Inventory, and the Compulsive Sexual Behavior Inventory-22. The sample included 152 male college students recruited in a Portuguese university using nonrandom methods. The measures were completed individually and anonymously. Findings on state psychopathology suggested that psychoticism may be one of the key dimensions associated with sexual compulsivity in male students. The personality traits of Neuroticism and Agreeableness were also significant predictors of sexual compulsivity. Findings on the mediating effects suggested that state psychopathology mediated the relationship between Neuroticism and sexual compulsivity but not between Agreeableness and sexual compulsivity. A psychopathological path (encompassing Neuroticism and state psychopathology) and a behavioral path (encompassing Agreeableness features) may be involved in sexual compulsivity as reported by a nonclinical sample of male students. © 2013 International Society for Sexual Medicine.

Solvent effects on the excited-state double proton transfer mechanism in the 7-azaindole dimer: a TDDFT study with the polarizable continuum model.

PubMed

Yu, Xue-Fang; Yamazaki, Shohei; Taketsugu, Tetsuya

2017-08-30

Solvent effects on the excited-state double proton transfer (ESDPT) mechanism in the 7-azaindole (7AI) dimer were investigated using the time-dependent density functional theory (TDDFT) method. Excited-state potential energy profiles along the reaction paths in a locally excited (LE) state and a charge transfer (CT) state were calculated using the polarizable continuum model (PCM) to include the solvent effect. A series of non-polar and polar solvents with different dielectric constants were used to examine the polarity effect on the ESDPT mechanism. The present results suggest that in a non-polar solvent and a polar solvent with a small dielectric constant, ESDPT follows a concerted mechanism, similar to the case in the gas phase. In a polar solvent with a relatively large dielectric constant, however, ESDPT is likely to follow a stepwise mechanism via a stable zwitterionic intermediate in the LE state on the adiabatic potential energy surface, although inclusion of zero-point vibrational energy (ZPE) corrections again suggests the concerted mechanism. In the meantime, the stepwise reaction path involving the CT state with neutral intermediates is also examined, and is found to be less competitive than the concerted or stepwise path in the LE state in both non-polar and polar solvents. The present study provides a new insight into the experimental controversy of the ESDPT mechanism of the 7AI dimer in a solution.

Neural evidence that three dimensions organize mental state representation: Rationality, social impact, and valence

PubMed Central

Tamir, Diana I.; Thornton, Mark A.; Contreras, Juan Manuel; Mitchell, Jason P.

2016-01-01

How do people understand the minds of others? Existing psychological theories have suggested a number of dimensions that perceivers could use to make sense of others’ internal mental states. However, it remains unclear which of these dimensions, if any, the brain spontaneously uses when we think about others. The present study used multivoxel pattern analysis (MVPA) of neuroimaging data to identify the primary organizing principles of social cognition. We derived four unique dimensions of mental state representation from existing psychological theories and used functional magnetic resonance imaging to test whether these dimensions organize the neural encoding of others’ mental states. MVPA revealed that three such dimensions could predict neural patterns within the medial prefrontal and parietal cortices, temporoparietal junction, and anterior temporal lobes during social thought: rationality, social impact, and valence. These results suggest that these dimensions serve as organizing principles for our understanding of other people. PMID:26621704

Evidence of mixed valence states in U M2Al 3 ( M = Ni, Pd) studied by X-ray photoemission spectroscopy

NASA Astrophysics Data System (ADS)

Fujimori, Shin-ichi; Saito, Yasuharu; Sato, Noriaki; Komatsubara, Takemi; Suzuki, Shoji; Sato, Shigeru; Ishii, Takehiko

1998-01-01

We have measured the XPS valence band and core-level spectra of U M2Al 3 ( M = Ni and Pd). The results are compared with those of reference materials, dilute alloy U 0.1La 0.9Pd 2Al 3 and itinerant 5 f compound URh 3. The similarity of the core-level spectra between UPd 2Al 3 and U 0.1La 0.9Pd 2Al 3 suggests that their core-level spectra are governed by the interaction between U 5 f and ligand states of neighboring palladium and aluminum sites, with negligible contributions from neighboring uranium states. A complex satellite structure, observed in the core-level spectra of U M2Al 3, suggests that the uranium atoms are in the strong mixed valence states with 5 f2(U 4+) and 5 f3(U 3+).

Reward for food odors: an fMRI study of liking and wanting as a function of metabolic state and BMI

PubMed Central

Jiang, Tao; Soussignan, Robert; Schaal, Benoist

2015-01-01

Brain reward systems mediate liking and wanting for food reward. Here, we explore the differential involvement of the following structures for these two components: the ventral and dorsal striatopallidal area, orbitofrontal cortex (OFC), anterior insula and anterior cingulate. Twelve healthy female participants were asked to rate pleasantness (liking of food and non-food odors) and the desire to eat (wanting of odor-evoked food) during event-related functional magnetic resonance imaging (fMRI). The subjective ratings and fMRI were performed in hunger and satiety states. Activations of regions of interest were compared as a function of task (liking vs wanting), odor category (food vs non-food) and metabolic state (hunger vs satiety). We found that the nucleus accumbens and ventral pallidum were differentially involved in liking or wanting during the hunger state, which suggests a reciprocal inhibitory influence between these structures. Neural activation of OFC subregions was correlated with either liking or wanting ratings, suggesting an OFC role in reward processing magnitude. Finally, during the hunger state, participants with a high body mass index exhibited less activation in neural structures underlying food reward processing. Our results suggest that food liking and wanting are two separable psychological constructs and may be functionally segregated within the cortico-striatopallidal circuit. PMID:24948157

The Effects of Romantic Love on Mentalizing Abilities

PubMed Central

Wlodarski, Rafael; Dunbar, Robin I. M.

2015-01-01

The effects of the human pair-bonded state of “romantic love” on cognitive function remain relatively unexplored. Theories on cognitive priming suggest that a state of love may activate love-relevant schemas, such as mentalizing about the beliefs of another individual, and may thus improve mentalizing abilities. On the other hand, recent functional MRI (fMRI) research on individuals who are in love suggests that several brain regions associated with mentalizing may be “deactivated” during the presentation of a love prime, potentially affecting mentalizing cognitions and behaviors. The current study aimed to investigate experimentally the effect of a love prime on a constituent aspect of mentalizing—the attribution of emotional states to others. Ninety-one participants who stated they were “deeply in love” with their romantic partner completed a cognitive task involving the assessment of emotional content of facial stimuli (the Reading the Mind in the Eyes task) immediately after the presentation of either a love prime or a neutral prime. Individuals were significantly better at interpreting the emotional states of others after a love prime than after a neutral prime, particularly males assessing negative emotional stimuli. These results suggest that presentation of a love stimulus can prime love-relevant networks and enhance subsequent performance on conceptually related mentalizing tasks. PMID:26167112

Impact of the basic state and MJO representation on MJO Pacific teleconnections in GCMs

NASA Astrophysics Data System (ADS)

Henderson, S. A.; Maloney, E. D.; Son, S. W.

2017-12-01

Teleconnection patterns induced by the Madden-Julian Oscillation (MJO) are known to significantly alter extratropical weather and climate patterns. However, accurate MJO representation has been difficult for many General Circulation Models (GCMs). Furthermore, many GCMs contain large basic state biases. These issues present challenges to the simulation of MJO teleconnections and, in turn, their associated extratropical impacts. This study examines the impacts of basic state quality and MJO representation on the quality of MJO teleconnection patterns in GCMs from phase 5 of the Coupled Model Intercomparison Project (CMIP5). Results suggest that GCMs assessed to have a good MJO but with large basic state biases have similarly low skill in reproducing MJO teleconnections as GCMs with poor MJO representation. In the good MJO models examined, poor teleconnection quality is associated with large errors in the zonal extent of the Pacific subtropical jet. Whereas the horizontal structure of MJO heating in the Indo-Pacific region is found to have modest impacts on the teleconnection patterns, results suggest that MJO heating east of the dateline can alter the teleconnection pattern characteristics over North America. These findings suggest that in order to accurately simulate the MJO teleconnection patterns and associated extratropical impacts, both the MJO and the basic state must be well represented.

Structural differences between the ready and unready oxidized states of [NiFe] hydrogenases.

PubMed

Volbeda, Anne; Martin, Lydie; Cavazza, Christine; Matho, Michaël; Faber, Bart W; Roseboom, Winfried; Albracht, Simon P J; Garcin, Elsa; Rousset, Marc; Fontecilla-Camps, Juan C

2005-05-01

[NiFe] hydrogenases catalyze the reversible heterolytic cleavage of molecular hydrogen. Several oxidized, inactive states of these enzymes are known that are distinguishable by their very different activation properties. So far, the structural basis for this difference has not been understood because of lack of relevant crystallographic data. Here, we present the crystal structure of the ready Ni-B state of Desulfovibrio fructosovorans [NiFe] hydrogenase and show it to have a putative mu-hydroxo Ni-Fe bridging ligand at the active site. On the other hand, a new, improved refinement procedure of the X-ray diffraction data obtained for putative unready Ni-A/Ni-SU states resulted in a more elongated electron density for the bridging ligand, suggesting that it is a diatomic species. The slow activation of the Ni-A state, compared with the rapid activation of the Ni-B state, is therefore proposed to result from the different chemical nature of the ligands in the two oxidized species. Our results along with very recent electrochemical studies suggest that the diatomic ligand could be hydro-peroxide.

Passivation of surface states of α-Fe2O3(0001) surface by deposition of Ga2O3 overlayers: A density functional theory study.

PubMed

Ulman, Kanchan; Nguyen, Manh-Thuong; Seriani, Nicola; Gebauer, Ralph

2016-03-07

There is a big debate in the community regarding the role of surface states of hematite in the photoelectrochemical water splitting. Experimental studies on non-catalytic overlayers passivating the hematite surface states claim a favorable reduction in the overpotential for the water splitting reaction. As a first step towards understanding the effect of these overlayers, we have studied the system Ga2O3 overlayers on hematite (0001) surfaces using first principles computations in the PBE+U framework. Our computations suggest that stoichiometric terminations of Ga2O3 overlayers are energetically more favored than the bare surface, at ambient oxygen chemical potentials. Energetics suggest that the overlayers prefer to grow via a layer-plus-island (Stranski-Krastanov) growth mode with a critical layer thickness of 1-2 layers. Thus, a complete wetting of the hematite surface by an overlayer of gallium oxide is thermodynamically favored. We establish that the effect of deposition of the Ga2O3 overlayers on the bare hematite surface is to passivate the surface states for the stoichiometric termination. For the oxygen terminated surface which is the most stable termination under photoelectrochemical conditions, the effect of deposition of the Ga2O3 overlayer is to passivate the hole-trapping surface state.

Motivational intensity modulates attentional scope: evidence from behavioral and ERP studies.

PubMed

Liu, Lei; Zhang, Guangnan; Zhou, Renlai; Wang, Zuowei

2014-10-01

Previous studies have found that affective states with high motivational intensity narrow attentional scope, whereas affective states with low motivational intensity broaden attentional scope. This conclusion, however, is based on fragmented evidence based on several separate studies. The present study tests this conclusion within a single study using both behavioral (Experiment 1) and neurophysiological (Experiment 2) measures. Experiment 1 showed that individuals had the global precedence effect in the neutral affective state. However, the global precedence effect was reduced for affective states with high motivational intensity, whereas the global precedence effect was not significantly enhanced for those with low motivational intensity. Experiment 2 replicated these results with event-related potential (ERP) recording. ERP results showed that affective states with high motivational intensity induced smaller N2 and greater late positive potential (LPP) amplitudes than low motivational intensity and neutral affective states. However, no differences were found between the low motivational intensity and neutral affective states. Furthermore, smaller LPP predicted the tendency a global attentional focus in the frontal and central areas and larger LPP predicted a narrowed focus in the frontal area. The findings suggested that high motivational intensity of affective states can affect attentional scope.

Steady-state pharmacokinetics of isotretinoin and its 4-oxo metabolite: implications for fetal safety.

PubMed

Nulman, I; Berkovitch, M; Klein, J; Pastuszak, A; Lester, R S; Shear, N; Koren, G

1998-10-01

Isotretinoin is the most potent human teratogen on the market. Women for whom contraception fails may conceive during or soon after discontinuing isotretinoin therapy, making its elimination kinetics a crucial determinant of fetal safety. The steady-state pharmacokinetics of isotretinoin and its major 4-oxo metabolite were studied in 16 adult patients treated for acne who were receiving doses that ranged from 0.47 to 1.7 mg/kg daily. This is the first study of the pharmacokinetics of isotretinoin in women of childbearing age (n = 11). The clinical efficacy and tolerability of isotretinoin was investigated, and the correlation between these data and steady-state serum concentrations of isotretinoin was tested. The concentration-time data best fitted a two-compartment open model with linear elimination. There was no correlation between efficacy and tolerability of isotretinoin and steady-state serum concentrations. There was no correlation between dose of isotretinoin and steady-state concentration, due to the large variability in apparent clearance. Values for elimination half-life (t1/2) of isotretinoin and its metabolite were 29+/-40 hours and 22+/-10 hours, respectively. These data suggest a longer elimination t1/2 of the parent drug than previously reported. This is probably due to the longer sampling time used in this study (as long as 28 days). This study suggests that a greater variability exists in the safe time after discontinuation of the drug for onset of conception.

Low frequency steady-state brain responses modulate large scale functional networks in a frequency-specific means.

PubMed

Wang, Yi-Feng; Long, Zhiliang; Cui, Qian; Liu, Feng; Jing, Xiu-Juan; Chen, Heng; Guo, Xiao-Nan; Yan, Jin H; Chen, Hua-Fu

2016-01-01

Neural oscillations are essential for brain functions. Research has suggested that the frequency of neural oscillations is lower for more integrative and remote communications. In this vein, some resting-state studies have suggested that large scale networks function in the very low frequency range (<1 Hz). However, it is difficult to determine the frequency characteristics of brain networks because both resting-state studies and conventional frequency tagging approaches cannot simultaneously capture multiple large scale networks in controllable cognitive activities. In this preliminary study, we aimed to examine whether large scale networks can be modulated by task-induced low frequency steady-state brain responses (lfSSBRs) in a frequency-specific pattern. In a revised attention network test, the lfSSBRs were evoked in the triple network system and sensory-motor system, indicating that large scale networks can be modulated in a frequency tagging way. Furthermore, the inter- and intranetwork synchronizations as well as coherence were increased at the fundamental frequency and the first harmonic rather than at other frequency bands, indicating a frequency-specific modulation of information communication. However, there was no difference among attention conditions, indicating that lfSSBRs modulate the general attention state much stronger than distinguishing attention conditions. This study provides insights into the advantage and mechanism of lfSSBRs. More importantly, it paves a new way to investigate frequency-specific large scale brain activities. © 2015 Wiley Periodicals, Inc.

Inferring the relative resilience of alternative states

USGS Publications Warehouse

Angeler, David G.; Allen, Craig R.; Rojo, Carmen; Alvarez-Cobelas, Miguel; Rodrigo, Maria A.; Sanchez-Carrillo, Salvador

2013-01-01

Ecological systems may occur in alternative states that differ in ecological structures, functions and processes. Resilience is the measure of disturbance an ecological system can absorb before changing states. However, how the intrinsic structures and processes of systems that characterize their states affects their resilience remains unclear. We analyzed time series of phytoplankton communities at three sites in a floodplain in central Spain to assess the dominant frequencies or “temporal scales” in community dynamics and compared the patterns between a wet and a dry alternative state. The identified frequencies and cross-scale structures are expected to arise from positive feedbacks that are thought to reinforce processes in alternative states of ecological systems and regulate emergent phenomena such as resilience. Our analyses show a higher species richness and diversity but lower evenness in the dry state. Time series modeling revealed a decrease in the importance of short-term variability in the communities, suggesting that community dynamics slowed down in the dry relative to the wet state. The number of temporal scales at which community dynamics manifested, and the explanatory power of time series models, was lower in the dry state. The higher diversity, reduced number of temporal scales and the lower explanatory power of time series models suggest that species dynamics tended to be more stochastic in the dry state. From a resilience perspective our results highlight a paradox: increasing species richness may not necessarily enhance resilience. The loss of cross-scale structure (i.e. the lower number of temporal scales) in community dynamics across sites suggests that resilience erodes during drought. Phytoplankton communities in the dry state are therefore likely less resilient than in the wet state. Our case study demonstrates the potential of time series modeling to assess attributes that mediate resilience. The approach is useful for assessing resilience of alternative states across ecological and other complex systems.

Suggestibility and suggestive modulation of the Stroop effect.

PubMed

Kirsch, Irving

2011-06-01

Although the induction of a hypnotic state does not seem necessary for suggestive modulation of the Stroop effect, this important phenomenon has seemed to be dependent on the subject's level of hypnotic suggestibility. Raz and Campbell's (2011) study indicates that suggestion can modulate the Stroop effect substantially in very low suggestible subjects, as well as in those who are highly suggestible. This finding casts doubt on the presumed mechanism by which suggestive modulation is brought about. Research aimed at uncovering the means by which low suggestible individuals are able to modulate the Stroop effect would be welcome, as would assessment of this effect in moderately suggestible people. Copyright © 2010 Elsevier Inc. All rights reserved.

Strategies for Dealing with Low Adoption of Agricultural Innovations: A Case Study of Farmers in Udenu L.G.A. of Enugu State, Nigeria

ERIC Educational Resources Information Center

Uguru, Chike; Ajayi, S. L.; Ogbu, Oliver C.

2015-01-01

A study to access the level of acceptance/adoption of agricultural innovations by farmers in Udenu Local Government Area of Enugu State was carried out. The aim was to find out the reasons behind the low acceptance/adoption of agricultural innovations by farmers in the area and to suggest possible strategies to address this ugly situation; as a…

Protection of surface states in topological nanoparticles

NASA Astrophysics Data System (ADS)

Siroki, Gleb; Haynes, Peter D.; Lee, Derek K. K.; Giannini, Vincenzo

2017-07-01

Topological insulators host protected electronic states at their surface. These states show little sensitivity to disorder. For miniaturization one wants to exploit their robustness at the smallest sizes possible. This is also beneficial for optical applications and catalysis, which favor large surface-to-volume ratios. However, it is not known whether discrete states in particles share the protection of their continuous counterparts in large crystals. Here we study the protection of the states hosted by topological insulator nanoparticles. Using both analytical and tight-binding simulations, we show that the states benefit from the same level of protection as those on a planar surface. The results hold for many shapes and sustain surface roughness which may be useful in photonics, spectroscopy, and chemistry. They complement past studies of large crystals—at the other end of possible length scales. The protection of the nanoparticles suggests that samples of all intermediate sizes also possess protected states.

Exponentially-Biased Ground-State Sampling of Quantum Annealing Machines with Transverse-Field Driving Hamiltonians

NASA Technical Reports Server (NTRS)

Mandra, Salvatore

2017-01-01

We study the performance of the D-Wave 2X quantum annealing machine on systems with well-controlled ground-state degeneracy. While obtaining the ground state of a spin-glass benchmark instance represents a difficult task, the gold standard for any optimization algorithm or machine is to sample all solutions that minimize the Hamiltonian with more or less equal probability. Our results show that while naive transverse-field quantum annealing on the D-Wave 2X device can find the ground-state energy of the problems, it is not well suited in identifying all degenerate ground-state configurations associated to a particular instance. Even worse, some states are exponentially suppressed, in agreement with previous studies on toy model problems [New J. Phys. 11, 073021 (2009)]. These results suggest that more complex driving Hamiltonians are needed in future quantum annealing machines to ensure a fair sampling of the ground-state manifold.

Traits, States, and Encoding Speed: Support for a Top-Down View of Neuroticism/State Relations

PubMed Central

Robinson, Michael D.; Clore, Gerald L.

2008-01-01

Recent theories suggest that trait neuroticism gains its pernicious power particularly among individuals less capable of making distinctions concerning present reality. Four studies, involving 272 undergraduates, sought to provide some basic, assessment-related support for such theories in the context of individual differences in choice reaction time, which reflect abilities to make distinctions at encoding. Studies 1–3 focused on somatic symptoms, whereas Study 4 focused on neurotic behaviors and negative affect. As predicted, neuroticism consistently interacted with categorization speed in predicting these dependent measures. Specifically, neuroticism/outcome relations were robust among individuals slow to make distinctions at encoding; by contrast, neuroticism did not predict the dependent measures among individuals fast to make distinctions. Such data reinforce suggestions that neuroticism is particularly pernicious among individuals less capable of making distinctions at encoding. PMID:17214593

Low-energy surface states in the normal state of α - PdBi 2 superconductor

DOE PAGES

Choi, Hongchul; Neupane, Madhab; Sasagawa, T.; ...

2017-08-25

Topological superconductors as characterized by Majorana surface states have been actively searched for their significance in fundamental science and technological implication. The large spin-orbit coupling in Bi-Pd binaries has stimulated extensive investigations on the topological surface states in these superconducting compounds. Here we report a study of normal-state electronic structure in a centrosymmetric α-PdBi 2 within density functional theory calculations. By investigating the electronic structure from the bulk to slab geometries in this system, we predict for the first time that α-PdBi 2 can host orbital-dependent and asymmetric Rashba surface states near the Fermi energy. This study suggests that α-PdBimore » 2 will be a good candidate to explore the relationship between superconductivity and topology in condensed matter physics.« less

Ab initio multireference study of the BN molecule

NASA Technical Reports Server (NTRS)

Martin, J. M. L.; Lee, Timothy J.; Scuseria, Gustavo E.; Taylor, Peter R.

1992-01-01

The lowest 1Sigma(+) and 3Pi states of the BN molecule are studied using multireference configuration interaction (MRCI) and averaged coupled-pair functional (ACPF) methods and large atomic natural orbital (ANO) basis sets, as well as several coupled cluster methods. Our calculations strongly support a 3Pi ground state, but the a1Sigma(+) state lies only 381 +/- 100/cm higher. The a1Sigma(+) state wave function exhibits strong multireference character and, consequently, the predictions of the perturbationally-based single-reference CCSD(T) coupled cluster method are not as reliable in this case as the multireference results. The theoretical predictions for the spectroscopic constants of BN are in good agreement with experiment for the Chi3Pi state, but strongly suggest a misassignment of the fundamental vibrational frequency for the a1Sigma(+) state.

Patterns of funding allocation for tuberculosis control in fragile states.

PubMed

Warsame, A; Patel, P; Checchi, F

2014-01-01

To assess recent (2006-2010) tuberculosis (TB) funding patterns in conflict and non-conflict-affected fragile states to inform global policy. The Creditor Reporting System was analysed for official development assistance funding disbursements towards TB control in 11 conflict-affected states, 17 non-conflict-affected fragile states and 38 comparable non-fragile states. The amounts of funding, funding relative to burden, funding relative to malaria and human immunodeficiency virus (HIV) control, disbursements relative to commitments, sources of funding as well as funding activities were extracted and analysed. Fragile states received on average more per capita for TB control relative to non-fragile states (US0.159 vs. US0.079). However conflict-affected fragile states received on average less per capita than non-conflict-affected states (US0.144 vs. US0.203), despite worse development indicators. Conflict-affected fragile states also received on average only 70% of TB funds already committed. Analysis by burden revealed the least disparity in funding in highest prevalence settings. Analysis of funding activities suggests increasing importance of TB-HIV integration, multidrug-resistant TB and research in both fragile and non-fragile states. Relative to non-conflict-affected fragile states, conflict-affected fragile states received approximately two thirds the per capita funding for TB. This study revealed disparities in TB control funding between fragile and non-fragile as well as between conflict and non-conflict-affected fragile states. Findings suggest possible avenues for improving the allocation of global TB funding.

Supplementary Reading Instruction in Alternative High Schools: A Statewide Survey of Educator Reported Practices and Barriers

ERIC Educational Resources Information Center

Wilkerson, Kimber L.; Yan, Min-Chi; Perzigian, Aaron B.; Cakiroglu, Orhan

2016-01-01

Recent data suggest that a majority of secondary students read below the level considered proficient on state standardized tests of reading. Alternative high schools, in particular, serve a high proportion of struggling readers. This survey study investigated reading instruction provided to struggling readers in alternative schools in one state by…

Mobile Livelihoods: The Sociocultural Practices of Circular Migrations between Puerto Rico and the United States.

ERIC Educational Resources Information Center

Duany, Jorge

2002-01-01

Documented livelihood practices of migrants based on a recent field study of population flows between Puerto Rico and the United States, comparing characteristics of multiple movers, onetime movers, and nonmovers residing in Puerto Rico. Results suggest that circular migration does not entail major losses in human capital for Puerto Rico, but can…

Tracking Ecstasy Trends in the United States with Data from Three National Drug Surveillance Systems

ERIC Educational Resources Information Center

Yacoubian, George S., Jr.

2003-01-01

Anecdotal reports have suggested that the use of 3,4-methylenedioxymeth-amphetamine (MDMA or "ecstasy") is a prodigious problem across the United States. Unfortunately, no longitudinal evidence exists to support this contention. In the current study, data from the Drug Abuse Warning Network (DAWN), Monitoring the Future (MTF), and…

Energy: Light, Sound, and Heat, Science (Experimental): 5311.04.

ERIC Educational Resources Information Center

Castaldi, June P.

This unit of instruction was designed as a basic course involving the study of light, sound, and heat at the junior high school level. The booklet lists the relevant state-adopted texts and states the performance objectives for the unit. It provides an outline of the course content and suggests experiments, demonstrations, field trips, and topics…

International Benchmarking and Determinants of Mathematics Achievement in Two Indian States

ERIC Educational Resources Information Center

Wu, Kin Bing; Goldschmidt, Pete; Boscardin, Christy Kim; Sankar, Deepa

2009-01-01

Evidence from cross-country studies suggests that the sustainability of India's rapid economic growth will be conditioned by the quality of its education. This paper analyzed a 2005 World Bank-sponsored survey of Grade Nine students in the states of Rajasthan and Orissa. The survey used internationally comparable items from the 1999 Trends of…

Regional changes and global connections: monitoring climate variability and change in the western United States

Treesearch

Henry F. Diaz

2004-01-01

Mountain ecosystems of the Western United States are complex and include cold desert biomes, such as those found in Nevada; subpolar biomes found in the upper treeline zone; and tundra ecosystems, occurring above timberline. Many studies (for example, Thompson 2000) suggest that high-elevation environments, comprising glaciers, snow, permafrost, water, and the...

Community Colleges in South Africa: Towards an Inclusive and Vibrant Further Education and Training. Phase One Report.

ERIC Educational Resources Information Center

Hoppers, Catherine Odora, Ed.

This report examines the current state of community colleges in South Africa. A pilot study was designed to assess the state of thinking, practice, partnership, possibilities, programming, restructuring, and needs with regards to South African community colleges. Preliminary findings suggest that, where community colleges do exist, there is a…

The Newspaper in the Classroom: Suggestions for Using Your Newspaper in Classrooms of Junior and Senior High Schools.

ERIC Educational Resources Information Center

Copley Newspapers, San Diego, CA. Dept. of Education.

Consisting of the combined findings of recent Newspaper in the Classroom Workshops and methods already successfully used in the schools in areas where Copley newspapers are published, this booklet provides techniques for using the newspaper in the following subject areas: social studies, United States history, United States government, world…

Alcohol and Drug Prevention Curriculum Resource Guide Grades 10-12: Social Studies--United States History.

ERIC Educational Resources Information Center

North Carolina State Dept. of Public Instruction, Raleigh. Alcohol and Drug Defense Program.

This curriculum resource guide on alcohol and drug prevention provides suggested activities for teachers of grades 10 through 12. Three integrated learning activities for United States history and healthful living are presented. The history goals are understanding that the years since 1945 have been years of great changes, and learning to organize…

Child Mortality, Women's Status, Economic Dependency, and State Strength: A Cross-National Study of Less Developed Countries.

ERIC Educational Resources Information Center

Shen, Ce; Williamson, John B.

1997-01-01

Data from 86 developing countries suggest that foreign investment and debt dependency have adverse indirect effects on child mortality--effects mediated by variables linked to industrialism theory and gender stratification theory: women's education, health, and reproductive autonomy and rate of economic growth. State strength was related to lower…

A Causal Contiguity Effect That Persists across Time Scales

ERIC Educational Resources Information Center

Kilic, Asli; Criss, Amy H.; Howard, Marc W.

2013-01-01

The contiguity effect refers to the tendency to recall an item from nearby study positions of the just recalled item. Causal models of contiguity suggest that recalled items are used as probes, causing a change in the memory state for subsequent recall attempts. Noncausal models of the contiguity effect assume the memory state is unaffected by…

Health Insurance for Public School Teachers in Wisconsin: A Good Value for Taxpayers or a Case of Market Abuse?

ERIC Educational Resources Information Center

Browne, Mark; Leetch, Linda

2000-01-01

A study examined one state's suggestion for more cost-effective health insurance for teachers. Health insurance coverage for public school teachers in Wisconsin is determined through a collective-bargaining process. The Wisconsin Education Association (WEA) Insurance Corporation is affiliated with the states largest teachers' union and provides…

Potential impacts of year-round sampling on monitoring presence- absence of invasive flora in the southern United States

Treesearch

Christopher M. Oswalt; Sonja N. Oswalt; W. Keith Moser

2012-01-01

Studies suggest that the southern United States is an area of primary concern with regards to the spread of nonnative invasive plant species. Recent data show that species such as Japanese honeysuckle (Lonicera japonica) and Nepalese browntop (Microstegium vimineum) are invading forests and displacing native species throughout the...

Methods for Upgrading an Intramural-Recreational Sports Program: An Agency Report.

ERIC Educational Resources Information Center

Newman, Richard E.; Miller, Michael T.

This study assessed the state of intramural-recreational (IR) programs at Peru State College (Nebraska) and offered suggestions for the improvement of existing IR programs. The existing IR sports program is directed by a part-time adjunct staff member with the aid of student assistants and receives limited support. Upgrading the directorship of…

Knowledge Activation versus Sentence Mapping When Representing Fictional Characters' Emotional States.

ERIC Educational Resources Information Center

Gernsbacher, Morton Ann; Robertson, Rachel R. W.

1992-01-01

In a study of knowledge activation and sentence mapping, subjects read stories that described concrete actions, and then the content of the stories was manipulated (i.e. stories were written that implied different emotional states). It is suggested that the more emotionally evoking situations one encounters the more memory traces are stored and…

Beyond Intimaphobia: Object Lessons from Foucault and Sade

ERIC Educational Resources Information Center

Greteman, Adam Joseph

2014-01-01

In this study I suggest ways of thinking through issues of intimacy that have emerged in the late twentieth and early twenty-first centuries in the USA. I propose a state of intimaphobia in education. However, I move beyond exposing this state of intimaphobia to offer particular readings of two philosophers of intimacy: Michel Foucault and the…

Urea-Induced Unfolding of the Immunity Protein Im9 Monitored by spFRET

PubMed Central

Tezuka-Kawakami, Tomoko; Gell, Chris; Brockwell, David J.; Radford, Sheena E.; Smith, D. Alastair

2006-01-01

We have studied the urea-induced unfolding of the E colicin immunity protein Im9 using diffusion single-pair fluorescence resonance energy transfer. Detailed examination of the proximity ratio of the native and denatured molecules over a wide range of urea concentrations suggests that the conformational properties of both species are denaturant-dependent. Whereas native molecules become gradually more expanded as urea concentration increases, denatured molecules show a dramatic dependence of the relationship between proximity ratio and denaturant concentration, consistent with substantial compaction of the denatured ensemble at low denaturant concentrations. Analysis of the widths of the proximity ratio distributions for each state suggests that whereas the native state ensemble is relatively narrow and homogeneous, the denatured state may possess heterogeneity in mildly denaturing conditions. PMID:16798813

5-HTTLPR Polymorphism Impacts Task-Evoked and Resting-State Activities of the Amygdala in Han Chinese

PubMed Central

Li, Sufang; Zou, Qihong; Li, Jun; Li, Jin; Wang, Deyi; Yan, Chaogan; Dong, Qi; Zang, Yu-Feng

2012-01-01

Background Prior research has shown that the amygdala of carriers of the short allele (s) of the serotonin transporter (5-HTT) gene (5-HTTLPR) have a larger response to negative emotional stimuli and higher spontaneous activity during the resting state than non-carriers. However, recent studies have suggested that the effects of 5-HTTLPR may be specific to different ethnic groups. Few studies have been conducted to address this issue. Methodology/Principal Findings Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) was conducted on thirty-eight healthy Han Chinese subjects (l/l group, n = 19; s/s group, n = 19) during the resting state and during an emotional processing task. Compared with the s/s group, the l/l group showed significantly increased regional homogeneity or local synchronization in the right amygdala during the resting state (|t|>2.028, p<0.05, corrected), but no significant difference was found in the bilateral amygdala in response to negative stimuli in the emotional processing task. Conclusions/Significance 5-HTTLPR can alter the spontaneous activity of the amygdala in Han Chinese. However, the effect of 5-HTTLPR on the amygdala both in task state and resting state in Asian population was no similar with Caucasians. They suggest that the effect of 5-HTTLPR on the amygdala may be modulated by ethnic differences. PMID:22574175

Rapid X-ray variability properties during the unusual very hard state in neutron-star low-mass X-ray binaries

NASA Astrophysics Data System (ADS)

Wijnands, R.; Parikh, A. S.; Altamirano, D.; Homan, J.; Degenaar, N.

2017-11-01

Here, we study the rapid X-ray variability (using XMM-Newton observations) of three neutron-star low-mass X-ray binaries (1RXS J180408.9-342058, EXO 1745-248 and IGR J18245-2452) during their recently proposed very hard spectral state. All our systems exhibit a strong to very strong noise component in their power density spectra (rms amplitudes ranging from 34 per cent to 102 per cent) with very low characteristic frequencies (as low as 0.01 Hz). These properties are more extreme than what is commonly observed in the canonical hard state of neutron-star low-mass X-ray binaries observed at X-ray luminosities similar to those we observe from our sources. This suggests that indeed the very hard state is a spectral-timing state distinct from the hard state, although we argue that the variability behaviour of IGR J18245-2452 is very extreme and possibly this source was in a very unusual state. We also compare our results with the rapid X-ray variability of the accreting millisecond X-ray pulsars IGR J00291+5934 and Swift J0911.9-6452 (also using XMM-Newton data) for which previously similar variability phenomena were observed. Although their energy spectra (as observed using the Swift X-ray telescope) were not necessarily as hard (i.e. for Swift J0911.9-6452) as for our other three sources, we conclude that likely both sources were also in very similar state during their XMM-Newton observations. This suggests that different sources that are found in this new state might exhibit different spectral hardness and one has to study both the spectral and the rapid variability to identify this unusual state.

Evangelical Protestants and the ACA: An Opening for Community-Based Primary Care?

PubMed

Franz, Berkeley; Skinner, Daniel

2016-07-01

Evangelical Protestants make up the largest religious subgroup in the United States, and previous research has shown that Evangelical churches are disproportionately active in community engagement and efforts toward social change. Although Evangelical Protestant perspectives have been considered with regard to persistent socioeconomic stratification and racial discrimination, less focus has been given to how churches interpret poor health outcomes within the United States. In particular, this research addresses how enduring health disparities are understood within the larger discussion of healthcare reform. Due to the similarity of approaches favored by participants in this study and community-based philosophy, a suggestion is made for future health policy dialogue. Although Evangelical Protestants have been most likely to reject all aspects of the Affordable Care Act, in many ways the findings of this study suggest the potential for successful future health policy collaboration. In particular, community-based primary care might appeal to Evangelicals and health professionals in the ongoing effort to improve population health and the quality of healthcare in the United States.

Vulnerability of US thermoelectric power generation to climate change when incorporating state-level environmental regulations

NASA Astrophysics Data System (ADS)

Liu, Lu; Hejazi, Mohamad; Li, Hongyi; Forman, Barton; Zhang, Xiao

2017-08-01

Previous modelling studies suggest that thermoelectric power generation is vulnerable to climate change, whereas studies based on historical data suggest the impact will be less severe. Here we explore the vulnerability of thermoelectric power generation in the United States to climate change by coupling an Earth system model with a thermoelectric power generation model, including state-level representation of environmental regulations on thermal effluents. We find that the impact of climate change is lower than in previous modelling estimates due to an inclusion of a spatially disaggregated representation of environmental regulations and provisional variances that temporarily relieve power plants from permit requirements. More specifically, our results indicate that climate change alone may reduce average generating capacity by 2-3% by the 2060s, while reductions of up to 12% are expected if environmental requirements are enforced without waivers for thermal variation. Our work highlights the significance of accounting for legal constructs and underscores the effects of provisional variances in addition to environmental requirements.

The relationship between older Americans act in-home services and low-care residents in nursing homes.

PubMed

Thomas, Kali S

2014-03-01

The aim of the study was to investigate the relationship between supportive services provided under Title III-B of the Older Americans Act (OAA) and the prevalence of low-care residents in nursing homes (NHs). State Program Reports (state-level expenditure and utilization data for each OAA service) and NH facility-level data were analyzed using a two-way fixed effects model. Results suggest that every additional 1% of the population age 65+ that receives personal care services is associated with a 0.8% decrease in the proportion of low-care residents in NHs. Despite efforts to rebalance long-term care, there are still many NH residents who have the functional capacity to live in a less restrictive environment. This is among the first studies to suggest that states that have invested in their in-home supportive services, particularly personal care services provided through the OAA, have proportionally fewer of these people.

The Effects of Transient Emotional State and Workload on Size Scaling in Perspective Displays

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tuan Q. Tran; Kimberly R. Raddatz

2006-10-01

Previous research has been devoted to the study of perceptual (e.g., number of depth cues) and cognitive (e.g., instructional set) factors that influence veridical size perception in perspective displays. However, considering that perspective displays have utility in high workload environments that often induce high arousal (e.g., aircraft cockpits), the present study sought to examine the effect of observers’ emotional state on the ability to perceive and judge veridical size. Within a dual-task paradigm, observers’ ability to make accurate size judgments was examined under conditions of induced emotional state (positive, negative, neutral) and high and low workload. Results showed that participantsmore » in both positive and negative induced emotional states were slower to make accurate size judgments than those not under induced emotional arousal. Results suggest that emotional state is an important factor that influences visual performance on perspective displays and is worthy of further study.« less

Impact of social service and public health spending on teenage birth rates across the USA: an ecological study.

PubMed

Sipsma, Heather L; Canavan, Maureen; Gilliam, Melissa; Bradley, Elizabeth

2017-06-13

To examine whether greater state-level spending on social and public health services such as income, education and public safety is associated with lower rates of teenage births in USA. Ecological study. USA. 50 states. Our primary outcome measure was teenage birth rates. For analyses, we constructed marginal models using repeated measures to test the effect of social spending on teenage birth rates, accounting for several potential confounders. The unadjusted and adjusted models across all years demonstrated significant effects of spending and suggested that higher spending rates were associated with lower rates of teenage birth, with effects slightly diminishing with each increase in spending (linear effect: B=-0.20; 95% CI -0.31 to 0.08; p<0.001 and quadratic effect: B=0.003; 95% CI 0.002 to 0.005; p<0.001). Higher state spending on social and public health services is associated with lower rates of teenage births. As states seek ways to limit healthcare costs associated with teenage birth rates, our findings suggest that protecting existing social service investments will be critical. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Impact of Langmuir Turbulence on Upper Ocean Response to Hurricane Edouard: Model and Observations

NASA Astrophysics Data System (ADS)

Blair, A.; Ginis, I.; Hara, T.; Ulhorn, E.

2017-12-01

Tropical cyclone intensity is strongly affected by the air-sea heat flux beneath the storm. When strong storm winds enhance upper ocean turbulent mixing and entrainment of colder water from below the thermocline, the resulting sea surface temperature cooling may reduce the heat flux to the storm and weaken the storm. Recent studies suggest that this upper ocean turbulence is strongly affected by different sea states (Langmuir turbulence), which are highly complex and variable in tropical cyclone conditions. In this study, the upper ocean response under Hurricane Edouard (2014) is investigated using a coupled ocean-wave model with and without an explicit sea state dependent Langmuir turbulence parameterization. The results are compared with in situ observations of sea surface temperature and mixed layer depth from AXBTs, as well as satellite sea surface temperature observations. Overall, the model results of mixed layer deepening and sea surface temperature cooling under and behind the storm are consistent with observations. The model results show that the effects of sea state dependent Langmuir turbulence can be significant, particularly on the mixed layer depth evolution. Although available observations are not sufficient to confirm such effects, some observed trends suggest that the sea state dependent parameterization might be more accurate than the traditional (sea state independent) parameterization.

How to Investigate Within-Subject Associations between Physical Activity and Momentary Affective States in Everyday Life: A Position Statement Based on a Literature Overview

PubMed Central

Kanning, Martina K.; Ebner-Priemer, Ulrich W.; Schlicht, Wolfgang Michael

2013-01-01

Several meta-analyses have investigated the association between physical activity and affective states and have found evidence suggesting that exercise exerts a positive effect on affective state. However, in this field of research, most studies have conducted between-subject analyses. Nonetheless, there is more and more interest in the within-subject associations between physical activity and momentary affective states in everyday life. This position statement pertains to this up-and-coming field of research and provides methodological recommendations for further studies. The paper is divided into three parts: first, we summarize and evaluate three methodological requirements necessary for the proper evaluation of within-subject associations between physical activity and momentary affective states in everyday life. We propose that the following issues should be considered: (a) to address the dynamic nature of such relationships, repeated assessments are necessary; (b) as activities performed in everyday life are mostly spontaneous and unconscious, an objective assessment of physical activity is useful; (c) given that recall of affective states is often affected by systematic distortions, real-time assessment is preferable. In sum, we suggest the use of ambulatory assessment techniques, and more specifically the combination of accelerometer-assessment of physical activity with an electronic diary assessment of the momentary affective state and additional context information. Second, we summarize 22 empirical studies published between 1980 and 2012 using ambulatory assessment to investigate within-subject associations between momentary affective states and physical activity in everyday life. Generally, the literature overview detects a positive association, which appears stronger among those studies that were of high methodological quality. Third, we propose the use of ambulatory assessment intervention (AAIs) strategies to change people’s behavior and to enable people to be active as often as possible during the day (e.g., reducing sitting time, taking more steps per day). PMID:23641221

The Student as a Physical Being

ERIC Educational Resources Information Center

Hubble, Jayne; and others

1969-01-01

The Study of Student Development at Kansas State University includes a physiological phase. Observations suggest importance of interaction of physical and social-psychological aspects of student development. (Author/CJ)

The Artful Dodgers: Directors of Ethnic Studies Programs

ERIC Educational Resources Information Center

Fenchak, Paul

1974-01-01

Of the vast amount of ethnic studies promoted by state education departments, one conclusion can be easily made: East European ethnic studies are conspicuously absent. Suggestions are given to increase the awareness of Eastern European culture and heritage and promote their inclusion in formal ethnic studies curriculum. (Author/DE)

An inventory of ambulance service regulatory programs in California.

PubMed

Narad, R A

1998-01-01

Ambulance regulation in California is the responsibility of numerous agencies on the state and local levels. By identifying and analyzing the variety of programs used in one state, this study establishes a framework for evaluation of state and local regulatory programs elsewhere. This study surveyed all California local EMS agencies (LEMSAs: California's equivalent of regional EMS organizations) to identify the types of regulatory programs used, the foci of these programs (e.g., equipment and personnel), and their application (e.g., public and private providers). All data acquired were analyzed using population parameters rather than inferential statistics. A response rate of 100% was obtained. Among the regulatory tools used are ordinances, contracts, and franchises. Regulatory standards vary widely as do their applications. Large counties and those that operate their own LEMSA have more extensive regulatory programs than do smaller counties and those who participate in multicounty agencies. Many of the enforcement mechanisms available are weak. This study suggests several policy implications for California and other states. The wide variation in the types of regulatory programs and the standards that are used suggest that the purpose and impact of regulatory programs should be studied further. The decentralization of the ambulance regulatory program and the lack of integration of ambulance regulations into EMS system planning also raise policy questions. In addition, the role of multicounty EMS agencies, as it relates to regulation of ambulance services, should be reviewed.

Dengue Virus Type 4 Phylogenetics in Brazil 2011: Looking beyond the Veil

PubMed Central

de Souza, Renato Pereira; Rocco, Iray M.; Maeda, Adriana Y.; Spenassatto, Carine; Bisordi, Ivani; Suzuki, Akemi; Silveira, Vivian R.; Silva, Sarai J. S.; Azevedo, Roberta M.; Tolentino, Fernanda M.; Assis, Jaqueline C.; Bassi, Margarida G.; Dambrós, Bibiana P.; Tumioto, Gabriela L.; Gregianini, Tatiana S.; Souza, Luiza Terezinha M.; Timenetsky, Maria do Carmo S. T.; Santos, Cecília L. S.

2011-01-01

Dengue Fever and Dengue Hemorrhagic Fever are diseases affecting approximately 100 million people/year and are a major concern in developing countries. In the present study, the phylogenetic relationship of six strains of the first autochthonous cases of DENV-4 infection occurred in Sao Paulo State, Parana State and Rio Grande do Sul State, Brazil, 2011 were studied. Nucleotide sequences of the envelope gene were determined and compared with sequences representative of the genotypes I, II, III and Sylvatic for DEN4 retrieved from GenBank. We employed a Bayesian phylogenetic approach to reconstruct the phylogenetic relationships of Brazilian DENV-4 and we estimated evolutionary rates and dates of divergence for DENV-4 found in Brazil in 2011. All samples sequenced in this study were located in Genotype II. The studied strains are monophyletic and our data suggest that they have been evolving separately for at least 4 to 6 years. Our data suggest that the virus might have been present in the region for some time, without being noticed by Health Surveillance Services due to a low level of circulation and a higher prevalence of DENV-1 and DENV- 2. PMID:22216365

Troops to Teaching: Lessons from English Teaching Assistants' Experiences of Foundation Degree Study

ERIC Educational Resources Information Center

Smith, Paul H.

2012-01-01

This article explores the suggestion that the UK should follow the lead of the United States and establish "Troops to Teaching" programmes. In particular, it examines the worth of the suggestion that non-graduate qualifications similar to those that have been designed for teaching assistants might be usefully employed to achieve this. In…

Interactive Whiteboards in State School Settings: Teacher Responses to Socio-Constructivist Hegemonies

ERIC Educational Resources Information Center

Schmid, Euline Cutrim; Whyte, Shona

2012-01-01

Recent CALL research suggests that the arrival of new technologies in the language classroom has led to an increased dominance of the socio-constructivist paradigm (Felix, 2006). Borg (2006) suggests, however, that the hegemony of this paradigm may not extend beyond well-researched university and private ESL contexts. The present study tests this…

Resting-state brain activity in the motor cortex reflects task-induced activity: A multi-voxel pattern analysis.

PubMed

Kusano, Toshiki; Kurashige, Hiroki; Nambu, Isao; Moriguchi, Yoshiya; Hanakawa, Takashi; Wada, Yasuhiro; Osu, Rieko

2015-08-01

It has been suggested that resting-state brain activity reflects task-induced brain activity patterns. In this study, we examined whether neural representations of specific movements can be observed in the resting-state brain activity patterns of motor areas. First, we defined two regions of interest (ROIs) to examine brain activity associated with two different behavioral tasks. Using multi-voxel pattern analysis with regularized logistic regression, we designed a decoder to detect voxel-level neural representations corresponding to the tasks in each ROI. Next, we applied the decoder to resting-state brain activity. We found that the decoder discriminated resting-state neural activity with accuracy comparable to that associated with task-induced neural activity. The distribution of learned weighted parameters for each ROI was similar for resting-state and task-induced activities. Large weighted parameters were mainly located on conjunctive areas. Moreover, the accuracy of detection was higher than that for a decoder whose weights were randomly shuffled, indicating that the resting-state brain activity includes multi-voxel patterns similar to the neural representation for the tasks. Therefore, these results suggest that the neural representation of resting-state brain activity is more finely organized and more complex than conventionally considered.

MDMA-Induced Dissociative State not Mediated by the 5-HT2A Receptor

PubMed Central

Puxty, Drew J.; Ramaekers, Johannes G.; de la Torre, Rafael; Farré, Magí; Pizarro, Neus; Pujadas, Mitona; Kuypers, Kim P. C.

2017-01-01

Previous research has shown that a single dose of MDMA induce a dissociative state, by elevating feelings of depersonalization and derealization. Typically, it is assumed that action on the 5-HT2A receptor is the mechanism underlying these psychedelic experiences. In addition, other studies have shown associations between dissociative states and biological parameters (heart rate, cortisol), which are elevated by MDMA. In order to investigate the role of the 5-HT2 receptor in the MDMA-induced dissociative state and the association with biological parameters, a placebo-controlled within-subject study was conducted including a single oral dose of MDMA (75 mg), combined with placebo or a single oral dose of the 5-HT2 receptor blocker ketanserin (40 mg). Twenty healthy recreational MDMA users filled out a dissociative states scale (CADSS) 90 min after treatments, which was preceded and followed by assessment of a number of biological parameters (cortisol levels, heart rate, MDMA blood concentrations). Findings showed that MDMA induced a dissociative state but this effect was not counteracted by pre-treatment with ketanserin. Heart rate was the only biological parameter that correlated with the MDMA-induced dissociative state, but an absence of correlation between these measures when participants were pretreated with ketanserin suggests an absence of directional effects of heart rate on dissociative state. It is suggested that the 5-HT2 receptor does not mediate the dissociative effects caused by a single dose of MDMA. Further research is needed to determine the exact neurobiology underlying this effect and whether these effects contribute to the therapeutic potential of MDMA. PMID:28744219

MDMA-Induced Dissociative State not Mediated by the 5-HT2A Receptor.

PubMed

Puxty, Drew J; Ramaekers, Johannes G; de la Torre, Rafael; Farré, Magí; Pizarro, Neus; Pujadas, Mitona; Kuypers, Kim P C

2017-01-01

Previous research has shown that a single dose of MDMA induce a dissociative state, by elevating feelings of depersonalization and derealization. Typically, it is assumed that action on the 5-HT 2A receptor is the mechanism underlying these psychedelic experiences. In addition, other studies have shown associations between dissociative states and biological parameters (heart rate, cortisol), which are elevated by MDMA. In order to investigate the role of the 5-HT 2 receptor in the MDMA-induced dissociative state and the association with biological parameters, a placebo-controlled within-subject study was conducted including a single oral dose of MDMA (75 mg), combined with placebo or a single oral dose of the 5-HT 2 receptor blocker ketanserin (40 mg). Twenty healthy recreational MDMA users filled out a dissociative states scale (CADSS) 90 min after treatments, which was preceded and followed by assessment of a number of biological parameters (cortisol levels, heart rate, MDMA blood concentrations). Findings showed that MDMA induced a dissociative state but this effect was not counteracted by pre-treatment with ketanserin. Heart rate was the only biological parameter that correlated with the MDMA-induced dissociative state, but an absence of correlation between these measures when participants were pretreated with ketanserin suggests an absence of directional effects of heart rate on dissociative state. It is suggested that the 5-HT 2 receptor does not mediate the dissociative effects caused by a single dose of MDMA. Further research is needed to determine the exact neurobiology underlying this effect and whether these effects contribute to the therapeutic potential of MDMA.

Affective problems and decline in cognitive state in older adults: a systematic review and meta-analysis.

PubMed

John, A; Patel, U; Rusted, J; Richards, M; Gaysina, D

2018-05-24

Evidence suggests that affective problems, such as depression and anxiety, increase risk for late-life dementia. However, the extent to which affective problems influence cognitive decline, even many years prior to clinical diagnosis of dementia, is not clear. The present study systematically reviews and synthesises the evidence for the association between affective problems and decline in cognitive state (i.e., decline in non-specific cognitive function) in older adults. An electronic search of PubMed, PsycInfo, Cochrane, and ScienceDirect was conducted to identify studies of the association between depression and anxiety separately and decline in cognitive state. Key inclusion criteria were prospective, longitudinal designs with a minimum follow-up period of 1 year. Data extraction and methodological quality assessment using the STROBE checklist were conducted independently by two raters. A total of 34 studies (n = 71 244) met eligibility criteria, with 32 studies measuring depression (n = 68 793), and five measuring anxiety (n = 4698). A multi-level meta-analysis revealed that depression assessed as a binary predictor (OR 1.36, 95% CI 1.05-1.76, p = 0.02) or a continuous predictor (B = -0.008, 95% CI -0.015 to -0.002, p = 0.012; OR 0.992, 95% CI 0.985-0.998) was significantly associated with decline in cognitive state. The number of anxiety studies was insufficient for meta-analysis, and they are described in a narrative review. Results of the present study improve current understanding of the temporal nature of the association between affective problems and decline in cognitive state. They also suggest that cognitive function may need to be monitored closely in individuals with affective disorders, as these individuals may be at particular risk of greater cognitive decline.

Cynicism, anger and cardiovascular reactivity during anger recall and human-computer interaction.

PubMed

Why, Yong Peng; Johnston, Derek W

2008-06-01

Cynicism moderated by interpersonal anger has been found to be related to cardiovascular reactivity. This paper reports two studies; Study 1 used an Anger Recall task, which aroused interpersonal anger, while participants in Study 2 engaged in a multitasking computer task, which aroused non-interpersonal anger via systematic manipulation of the functioning of the computer mouse. The Cynicism by State Anger interaction was significant for blood pressure arousal in Study 2 but not for Study 1: in Study 2, when State Anger was high, cynicism was positively related to blood pressure arousal but when State Anger was low, cynicism was negatively related to blood pressure arousal. For both studies, when State Anger was low, cynicism was positively related to cardiac output arousal and negatively related to vascular arousal. The results suggest that Cynicism-State Anger interaction can be generalised to non-social anger-arousing situations for hemodynamic processes but blood pressure reactivity is task-dependent. The implication for the role of job control and cardiovascular health during human-computer interactions is discussed.

Correlates of engaging in survival sex among homeless youth and young adults.

PubMed

Walls, N Eugene; Bell, Stephanie

2011-09-01

Using a sample of 1,625 homeless youth and young adults aged 10 to 25 from 28 different states in the United States, this study examines the correlates of having engaged in survival sex. Findings suggest that differences exist based on demographic variables (gender, age, race, and sexual orientation), lifetime drug use (inhalants, Valium™, crack cocaine, alcohol, Coricidin™, and morphine), recent drug use (alcohol, ecstasy, heroin, and methamphetamine), mental health variables (suicide attempts, familial history of substance use, and having been in substance abuse treatment), and health variables (sharing needles and having been tested for HIV). In addition to replicating previous findings, this study's findings suggest that African American youth; gay, lesbian, or bisexual youth; and youth who had been tested for HIV were significantly more likely to have engaged in survival sex than White, heterosexual youth, and youth who had not been tested for HIV, respectively. Implications for interventions with youth and suggestions for future research are discussed.

Prescription Drug Utilization and Reimbursement Increased Following State Medicaid Expansion in 2014.

PubMed

Mahendraratnam, Nirosha; Dusetzina, Stacie B; Farley, Joel F

2017-03-01

The Affordable Care Act (ACA) expanded health care and medication insurance coverage through Medicaid expansion in select states. Expansion has the potential to increase the availability of health services to patients, including prescription medications. However, limited studies have examined how expansion affected prescription drug utilization and reimbursement. To compare prescription drug utilization (number of prescriptions filled) and reimbursement trends between states that did and did not expand Medicaid coverage in 2014, while accounting for known effects of expansion on Medicaid enrollment. We conducted a comparative interrupted time series using retrospective Medicaid state drug utilization data from 2011 to 2014. After inclusion/exclusion criteria, 8 states that expanded Medicaid in 2014 and 10 states that did not expand Medicaid were studied. Primary outcomes were changes in quarterly prescription drug utilization and quarterly total prescription drug reimbursement before and after expansion. To account for increases in enrollment in expansion states, secondary outcomes were per-member-per-quarter (PMPQ) utilization and reimbursement before and after expansion. Expansion states experienced a 1.4 million prescriptions per quarter and $163 million per quarter increase in utilization and reimbursement above the change in rates observed in nonexpansion states after expansion (P < 0.001). Specifically, 1 year after ACA implementation, expansion states used 17.0% more prescriptions and spent 36.1% more in reimbursement than the quarter preceding expansion. Expansion and nonexpansion states experienced significant drops in PMPQ prescriptions immediately after expansion (P < 0.001), but PMPQ prescriptions and reimbursement trends increased by the end of the postexpansion period in expansion states (P < 0.029 and P < 0.001, respectively). Study results suggest that Medicaid expansion offers vulnerable patients who were previously uninsured increased access to health care resources, specifically prescription drugs. Although this hypothesis would benefit from further testing, it aligns with previous studies that have shown that Medicaid expansion has led to increased access to coverage and care. While enrollment contributes to the increase in prescription utilization and reimbursement, the drop in PMPQ utilization suggests that the patients entering the program are healthier than existing patients. This shows that risk pooling is working. However, the increase in PMPQ reimbursement suggests that new enrollment may not be the only factor driving reimbursement changes. Factors such as changes in product mix, risk pool composition, and drug pricing and their effects on total and per-member reimbursement should be evaluated in future studies. No outside funding supported this study. Mahendraratnam is currently a Worldwide Health Economics and Outcomes Research Pre-doctoral Fellow at Bristol-Myers Squibb and previously provided advisory services to public and private sector clients while employed at Avalere Health, an Inovalon Company, as well as completed an internship at Genentech, a member of the Roche Group. Farley and Dusetzina have no conflicts of interest to report. Preliminary results of this study were presented at the 2016 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) 21st Annual Meeting in Washington, DC, on May 21-25, 2016, and the 2016 AcademyHealth Annual Research Meeting (ARM) in Boston, Massachusetts, on June 26-28, 2016. Study concept and design were contributed by Farley, Mahendraratnam, and Dusetzina. Mahendraratnam, Farley, and Dusetzina collected the data, and data interpretation was performed by all the authors. The manuscript was written by Mahendraratnam, Farley, and Dusetzina and revised by Farley, Dusetzina, and Mahendraratnam.

Resting state EEG abnormalities in autism spectrum disorders

PubMed Central

2013-01-01

Autism spectrum disorders (ASD) are a group of complex and heterogeneous developmental disorders involving multiple neural system dysfunctions. In an effort to understand neurophysiological substrates, identify etiopathophysiologically distinct subgroups of patients, and track outcomes of novel treatments with translational biomarkers, EEG (electroencephalography) studies offer a promising research strategy in ASD. Resting-state EEG studies of ASD suggest a U-shaped profile of electrophysiological power alterations, with excessive power in low-frequency and high-frequency bands, abnormal functional connectivity, and enhanced power in the left hemisphere of the brain. In this review, we provide a summary of recent findings, discuss limitations in available research that may contribute to inconsistencies in the literature, and offer suggestions for future research in this area for advancing the understanding of ASD. PMID:24040879

DOE Office of Scientific and Technical Information (OSTI.GOV)

Auranen, K.; Uusitalo, J.; Juutinen, S.

A newly observed isomeric intruder ½ + state [T ½=3.5(6)ms] is identified in 203At using a gas-filled recoil separator and fusion-evaporation reactions. The isomer is depopulated through a cascade of E3 and mixed M1/E2 transitions to the 9/2 – ground state, and it is suggested to originate from the π(s ½) –1 configuration. In addition, the structures above the ½ + state in 203At and 197At are studied using in-beam γ-ray spectroscopy, recoil-decay tagging, and recoil-isomer decay tagging methods. As a result, the ½ + state is fed from 3/2 + and 5/2 + states, and the origin of thesemore » states are discussed.« less

Measurement-based quantum teleportation on finite AKLT chains

NASA Astrophysics Data System (ADS)

Fujii, Akihiko; Feder, David

In the measurement-based model of quantum computation, universal quantum operations are effected by making repeated local measurements on resource states which contain suitable entanglement. Resource states include two-dimensional cluster states and the ground state of the Affleck-Kennedy-Lieb-Tasaki (AKLT) state on the honeycomb lattice. Recent studies suggest that measurements on one-dimensional systems in the Haldane phase teleport perfect single-qubit gates in the correlation space, protected by the underlying symmetry. As laboratory realizations of symmetry-protected states will necessarily be finite, we investigate the potential for quantum gate teleportation in finite chains of a bilinear-biquadratic Hamiltonian which is a generalization of the AKLT model representing the full Haldane phase.

Generation of Path-Encoded Greenberger-Horne-Zeilinger States

NASA Astrophysics Data System (ADS)

Bergamasco, N.; Menotti, M.; Sipe, J. E.; Liscidini, M.

2017-11-01

We study the generation of Greenberger-Horne-Zeilinger (GHZ) states of three path-encoded photons. Inspired by the seminal work of Bouwmeester et al. [Phys. Rev. Lett. 82, 1345 (1999), 10.1103/PhysRevLett.82.1345] on polarization-entangled GHZ states, we find a corresponding path representation for the photon states of an optical circuit, identify the elements required for the state generation, and propose a possible implementation of our strategy. Besides the practical advantage of employing an integrated system that can be fabricated with proven lithographic techniques, our example suggests that it is possible to enhance the generation efficiency by using microring resonators.

Redistributive Fee Increases, Net Attendance Costs, and the Distribution of Students at the Public University.

ERIC Educational Resources Information Center

Hilmer, Michael J.

2001-01-01

Studies the effect of net attendance costs on student-enrollment patterns at in-state public 4-year colleges. Findings suggest that when net attendance costs increase, students without financial aid, especially high-test, black, and Hispanic students, may be less likely to attend in-state public 4-year colleges. (Contains 28 references.) (PKP)

Status and Developments of eLearning in the EU10 Member States: The Cases of Estonia, Hungary and Slovenia

ERIC Educational Resources Information Center

Ala-Mutka, Kirsti; Gaspar, Pal; Kismihok, Gabor; Suurna, Margit; Vehovar, Vasja

2010-01-01

This article summarises research carried out between 2006 and 2008 by IPTS (Institution for Prospective Technological Studies) in collaboration with a consortium of experts from 10 member states, led by ICEGEC. The project gathered information on eLearning developments to assess drivers and barriers and to suggest implications for policy and…

An Application of Durkheim's Theory of Suicide to Prison Suicide Rates in the United States

ERIC Educational Resources Information Center

Tartaro, Christine; Lester, David

2005-01-01

E. Durkheim (1897) suggested that the societal rate of suicide might be explained by societal factors, such as marriage, divorce, and birth rates. The current study examined male prison suicide rates and suicide rates for men in the total population in the United States and found that variables based on Durkheim's theory of suicide explained…

Fake snakes uncover chimpanzees' mind-reading ability.

PubMed

Hirata, Satoshi

2018-04-27

Crockford et al. (2017, Science Advances, 3(11), e1701742) conducted experimental studies in the wild in Africa to investigate the ability of chimpanzees to understand the mental states of other conspecific individuals. Their findings suggest that chimpanzees understand whether or not other individuals are aware of dangers, and they behave differently according to their understanding about the mental states of other individuals.

Attitudes of Students towards the Use of Library Course in Bendel State University, Ekpoma.

ERIC Educational Resources Information Center

Ojo-Igbinoba, M. E.

1991-01-01

Summarizes the results of a study of students' attitudes toward a library orientation/bibliographic instruction and user education course at Bendel State University in Nigeria. These results indicate that the students found the course very useful both in academic work and in social life. Suggestions are made for the improvement of the course. The…

Are Residents Losing Their Edge in Public University Admissions? The Case at the University of Washington. Schools in Crisis: Making Ends Meet

ERIC Educational Resources Information Center

Blume, Grant; Roza, Marguerite

2012-01-01

This case study examines admissions data at the University of Washington (UW) in order to quantify the effect on admissions standards for residents versus nonresidents. Like many other state flagship universities, the UW has suffered from constrained state revenues during the recent recessionary years. The findings suggest that Washington…

Impact of social service and public health spending on teenage birth rates across the USA: an ecological study

PubMed Central

Sipsma, Heather L; Canavan, Maureen; Gilliam, Melissa; Bradley, Elizabeth

2017-01-01

Objective To examine whether greater state-level spending on social and public health services such as income, education and public safety is associated with lower rates of teenage births in USA. Design Ecological study. Setting USA. Participants 50 states. Primary outcome measure Our primary outcome measure was teenage birth rates. For analyses, we constructed marginal models using repeated measures to test the effect of social spending on teenage birth rates, accounting for several potential confounders. Results The unadjusted and adjusted models across all years demonstrated significant effects of spending and suggested that higher spending rates were associated with lower rates of teenage birth, with effects slightly diminishing with each increase in spending (linear effect: B=−0.20; 95% CI −0.31 to 0.08; p<0.001 and quadratic effect: B=0.003; 95% CI 0.002 to 0.005; p<0.001). Conclusion Higher state spending on social and public health services is associated with lower rates of teenage births. As states seek ways to limit healthcare costs associated with teenage birth rates, our findings suggest that protecting existing social service investments will be critical. PMID:28611088

You are not alone: relatedness reduces adverse effects of state orientation on well-being under stress.

PubMed

Chatterjee, Monischa B; Baumann, Nicola; Osborne, Danny

2013-04-01

A low ability to self-regulate emotions (state orientation) is associated with reduced well-being--especially under stress. Until now, research has approached this topic from an asocial perspective that views the self as devoid from relatedness concerns. However, people are social creatures who benefit from their relationships with others. As such, we expected that personally valuing (Study 1) and experimentally priming (Study 2) a sense of relatedness with others would act as a buffer against stress-related impairments in state-oriented individuals. In Study 1, high (vs. low) benevolence values removed the adverse effect of state orientation on well-being found under stressful life circumstances. In Study 2, focusing on similarities (vs. differences) while comparing oneself with a friend removed the adverse effect of state orientation on recovery from a negative mood induction. Our findings suggest that individuals with low self-regulatory competencies may profit from valuing and directing their attention toward their relatedness with others.

Teaching the U.S. Maritime Tradition.

ERIC Educational Resources Information Center

Heitzmann, William Ray

1982-01-01

Suggests ways that information about the maritime industry can be incorporated into K-12 social studies. The author shows how maritime information can be integrated into the study of state and local history, career education, and interdisciplinary studies. A list of resources on maritime information is included. (AM)

Study Guide in Health Economics.

ERIC Educational Resources Information Center

Dawson, George; Jablon, Bert

Prepared to assist students at Empire State College in developing learning contracts for the study of the economics of health care delivery, this study guide discusses various aspects of the topic, suggests student projects, and provides an extensive bibliography. First, introductory material discusses the relationship of economics to health care…

Solid-State Lighting 2017 Suggested Research Topics

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2017-09-29

A 2017 update to the Solid-State Lighting R&D Plan that is divided into two documents. The first document describes a list of suggested SSL priority research topics and the second document provides context and background, including information drawn from technical, market, and economic studies. Widely referenced by industry and government both here and abroad, these documents reflect SSL stakeholder inputs on key R&D topics that will improve efficacy, reduce cost, remove barriers to adoption, and add value for LED and OLED lighting solutions over the next three to five years, and discuss those applications that drive and prioritize the specificmore » R&D.« less

Solid-State Lighting 2017 Suggested Research Topics

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

A 2017 update to the Solid-State Lighting R&D Plan that is divided into two documents. The first document describes a list of suggested SSL priority research topics and the second document provides context and background, including information drawn from technical, market, and economic studies. Widely referenced by industry and government both here and abroad, these documents reflect SSL stakeholder inputs on key R&D topics that will improve efficacy, reduce cost, remove barriers to adoption, and add value for LED and OLED lighting solutions over the next three to five years, and discuss those applications that drive and prioritize the specificmore » R&D.« less

Probabilistic models in human sensorimotor control

PubMed Central

Wolpert, Daniel M.

2009-01-01

Sensory and motor uncertainty form a fundamental constraint on human sensorimotor control. Bayesian decision theory (BDT) has emerged as a unifying framework to understand how the central nervous system performs optimal estimation and control in the face of such uncertainty. BDT has two components: Bayesian statistics and decision theory. Here we review Bayesian statistics and show how it applies to estimating the state of the world and our own body. Recent results suggest that when learning novel tasks we are able to learn the statistical properties of both the world and our own sensory apparatus so as to perform estimation using Bayesian statistics. We review studies which suggest that humans can combine multiple sources of information to form maximum likelihood estimates, can incorporate prior beliefs about possible states of the world so as to generate maximum a posteriori estimates and can use Kalman filter-based processes to estimate time-varying states. Finally, we review Bayesian decision theory in motor control and how the central nervous system processes errors to determine loss functions and optimal actions. We review results that suggest we plan movements based on statistics of our actions that result from signal-dependent noise on our motor outputs. Taken together these studies provide a statistical framework for how the motor system performs in the presence of uncertainty. PMID:17628731

Mental Simulation of Visceral States Affects Preferences and Behavior

PubMed Central

Steinmetz, Janina; Tausen, Brittany M.; Risen, Jane L.

2017-01-01

Preferences and behavior are heavily influenced by one’s current visceral experience, yet people often fail to anticipate such effects. Although research suggests that this gap is difficult to overcome—to act as if in another visceral state—research on mental simulation has demonstrated that simulations can substitute for experiences, albeit to a weaker extent. We examine whether mentally simulating visceral states can impact preferences and behavior. We show that simulating a specific visceral state (e.g., being cold or hungry) shifts people’s preferences for relevant activities (Studies 1a-2) and choices of food portion sizes (Study 3). Like actual visceral experiences, mental simulation only affects people’s current preferences but not their general preferences (Study 4). Finally, people project simulated states onto similar others, as is the case for actual visceral experiences (Study 5). Thus, mental simulation may help people anticipate their own and others’ future preferences, thereby improving their decision making. PMID:29161953

Mild Social Stress in Mice Produces Opioid-Mediated Analgesia in Visceral but Not Somatic Pain States.

PubMed

Pitcher, Mark H; Gonzalez-Cano, Rafael; Vincent, Kathleen; Lehmann, Michael; Cobos, Enrique J; Coderre, Terence J; Baeyens, José M; Cervero, Fernando

2017-06-01

Visceral pain has a greater emotional component than somatic pain. To determine if the stress-induced analgesic response is differentially expressed in visceral versus somatic pain states, we studied the effects of a mild social stressor in either acute visceral or somatic pain states in mice. We show that the presence of an unfamiliar conspecific mouse (stranger) in an adjacent cubicle of a standard transparent observation box produced elevated plasma corticosterone levels compared with mice tested alone, suggesting that the mere presence of a stranger is stressful. We then observed noxious visceral or somatic stimulation-induced nociceptive behavior in mice tested alone or in mildly stressful conditions (ie, beside an unfamiliar stranger). Compared with mice tested alone, the presence of a stranger produced a dramatic opioid-dependent reduction in pain behavior associated with visceral but not somatic pain. This social stress-induced reduction of visceral pain behavior relied on visual but not auditory/olfactory cues. These findings suggest that visceral pain states may provoke heightened responsiveness to mild stressors, an effect that could interfere with testing outcomes during simultaneous behavioral testing of multiple rodents. In mice, mild social stress due to the presence of an unfamiliar conspecific mouse reduces pain behavior associated with noxious visceral but not somatic stimulation, suggesting that stress responsiveness may be enhanced in visceral pain versus somatic pain states. Published by Elsevier Inc.

Reward for food odors: an fMRI study of liking and wanting as a function of metabolic state and BMI.

PubMed

Jiang, Tao; Soussignan, Robert; Schaal, Benoist; Royet, Jean-Pierre

2015-04-01

Brain reward systems mediate liking and wanting for food reward. Here, we explore the differential involvement of the following structures for these two components: the ventral and dorsal striatopallidal area, orbitofrontal cortex (OFC), anterior insula and anterior cingulate. Twelve healthy female participants were asked to rate pleasantness (liking of food and non-food odors) and the desire to eat (wanting of odor-evoked food) during event-related functional magnetic resonance imaging (fMRI). The subjective ratings and fMRI were performed in hunger and satiety states. Activations of regions of interest were compared as a function of task (liking vs wanting), odor category (food vs non-food) and metabolic state (hunger vs satiety). We found that the nucleus accumbens and ventral pallidum were differentially involved in liking or wanting during the hunger state, which suggests a reciprocal inhibitory influence between these structures. Neural activation of OFC subregions was correlated with either liking or wanting ratings, suggesting an OFC role in reward processing magnitude. Finally, during the hunger state, participants with a high body mass index exhibited less activation in neural structures underlying food reward processing. Our results suggest that food liking and wanting are two separable psychological constructs and may be functionally segregated within the cortico-striatopallidal circuit. © The Author (2014). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

Affect intensity and processing fluency of deterrents.

PubMed

Holman, Andrei

2013-01-01

The theory of emotional intensity (Brehm, 1999) suggests that the intensity of affective states depends on the magnitude of their current deterrents. Our study investigated the role that fluency--the subjective experience of ease of information processing--plays in the emotional intensity modulations as reactions to deterrents. Following an induction phase of good mood, we manipulated both the magnitude of deterrents (using sets of photographs with pre-tested potential to instigate an emotion incompatible with the pre-existent affective state--pity) and their processing fluency (normal vs. enhanced through subliminal priming). Current affective state and perception of deterrents were then measured. In the normal processing conditions, the results revealed the cubic effect predicted by the emotional intensity theory, with the initial affective state being replaced by the one appropriate to the deterrent only in participants exposed to the high magnitude deterrence. In the enhanced fluency conditions the emotional intensity pattern was drastically altered; also, the replacement of the initial affective state occurred at a lower level of deterrence magnitude (moderate instead of high), suggesting the strengthening of deterrence emotional impact by enhanced fluency.

Imaging the equilibrium state and magnetization dynamics of partially built hard disk write heads

DOE Office of Scientific and Technical Information (OSTI.GOV)

Valkass, R. A. J., E-mail: rajv202@ex.ac.uk; Yu, W.; Shelford, L. R.

Four different designs of partially built hard disk write heads with a yoke comprising four repeats of NiFe (1 nm)/CoFe (50 nm) were studied by both x-ray photoemission electron microscopy (XPEEM) and time-resolved scanning Kerr microscopy (TRSKM). These techniques were used to investigate the static equilibrium domain configuration and the magnetodynamic response across the entire structure, respectively. Simulations and previous TRSKM studies have made proposals for the equilibrium domain configuration of similar structures, but no direct observation of the equilibrium state of the writers has yet been made. In this study, static XPEEM images of the equilibrium state of writer structures weremore » acquired using x-ray magnetic circular dichroism as the contrast mechanism. These images suggest that the crystalline anisotropy dominates the equilibrium state domain configuration, but competition with shape anisotropy ultimately determines the stability of the equilibrium state. Dynamic TRSKM images were acquired from nominally identical devices. These images suggest that a longer confluence region may hinder flux conduction from the yoke into the pole tip: the shorter confluence region exhibits clear flux beaming along the symmetry axis, whereas the longer confluence region causes flux to conduct along one edge of the writer. The observed variations in dynamic response agree well with the differences in the equilibrium magnetization configuration visible in the XPEEM images, confirming that minor variations in the geometric design of the writer structure can have significant effects on the process of flux beaming.« less

Culture and medical decision making: Healthcare consumer perspectives in Japan and the United States.

PubMed

Alden, Dana L; Friend, John M; Lee, Angela Y; de Vries, Marieke; Osawa, Ryosuke; Chen, Qimei

2015-12-01

Two studies identified core value influences on medical decision-making processes across and within cultures. In Study 1, Japanese and American adults reported desired levels of medical decision-making influence across conditions that varied in seriousness. Cultural antecedents (interdependence, independence, and power distance) were also measured. In Study 2, American adults reviewed a colorectal cancer screening decision aid. Decision preparedness was measured along with interdependence, independence, and desire for medical information. In Study 1, higher interdependence predicted stronger desire for decision-making information in both countries, but was significantly stronger in Japan. The path from information desire to decision-making influence desire was significant only in Japan. The independence path to desire for decision-making influence was significant only in the United States. Power distance effects negatively predicted desire for decision-making influence only in the United States. For Study 2, high (low) interdependents and women (men) in the United States felt that a colorectal cancer screening decision aid helped prepare them more (less) for a medical consultation. Low interdependent men were at significantly higher risk for low decision preparedness. Study 1 suggests that Japanese participants may tend to view medical decision-making influence as an interdependent, information sharing exchange, whereas American respondents may be more interested in power sharing that emphasizes greater independence. Study 2 demonstrates the need to assess value influences on medical decision-making processes within and across cultures and suggests that individually tailored versions of decision aids may optimize decision preparedness. (c) 2015 APA, all rights reserved).

Polarization Dependence of Resonant Inelastic Scattering in Insulating Copper Oxides

NASA Astrophysics Data System (ADS)

Hill, John

2000-03-01

Recent work on a number of copper oxides, including Nd_2CuO_4, YBa_2Cu_3O7 and CuGeO3 is reported. In each case, an excitation of ~ 6 eV is observed when the incident energy is tuned through the Cu K-edge. Numerical calculations based on the Anderson Impurity model for Nd_2CuO4 suggest that this feature is a charge-transfer excitation to the antibonding state. Studies of the incident energy and polarization dependence of this excitation in Nd_2CuO4 reveal that the incident polarization selects the intermediate states participating in the resonance process. In particular, when the incident polarization is largely perpendicular to the copper oxide planes, a single resonance is observed at 8990 eV, corresponding to the \\underline 1s3d^94p_π intermediate state. Conversely with the incident polarization is aligned with the planes, an enhancement is observed at 8999.5 eV, associated with the \\underline 1s3d^94p_σ intermediate state. No enhancement is observed for the \\underline 1s3d^10\\underline L 4p intermediate state in either case. It is suggested that the systematic absence of this resonance is associated with non-local effects active in this intermediate state. This suggestion is supported by multi-copper-site calculations, and by our studies of CuGeO_3. In this latter compound, the CuO4 plaquettes are arranged in one dimensional edge-sharing chains, rather than the two dimensional corner sharing network of Nd_2CuO_4. Non-local effects are expected to be suppressed in such a case, and indeed two resonances are observed in CuGeO_3. This work further suggests that this technique may provide both a sensitive measure of the role of non-local effects in the excitation spectrum, and a stringent test for state-of-the-art electronic structure calculations. It is a great pleasure to acknowledge my collaborators in this work, L.E. Berman, W.A.L. Caliebe, R.L. Greene, K. Hämäläinen, K. Hirota, S. Huotari, T. Idé. C.-C. Kao, A. Kotani, T. Masuda, M. Matsubara, J.L. Peng, I. Tsukada, K. Uchinokura, and M. v. Zimmermann.

X-ray Absorption Spectroscopy Study of the Effect of Rh doping in Sr2IrO4

PubMed Central

Sohn, C. H.; Cho, Deok-Yong; Kuo, C.-T.; Sandilands, L. J.; Qi, T. F.; Cao, G.; Noh, T. W.

2016-01-01

We investigate the effect of Rh doping in Sr2IrO4 using X-ray absorption spectroscopy (XAS). We observed appearance of new electron-addition states with increasing Rh concentration (x in Sr2Ir1−xRhxO4) in accordance with the concept of hole doping. The intensity of the hole-induced state is however weak, suggesting weakness of charge transfer (CT) effect and Mott insulating ground states. Also, Ir Jeff = 1/2 upper Hubbard band shifts to lower energy as x increases up to x = 0.23. Combined with optical spectroscopy, these results suggest a hybridisation-related mechanism, in which Rh doping can weaken the (Ir Jeff = 1/2)–(O 2p) orbital hybridisation in the in-planar Rh-O-Ir bond networks. PMID:27025538

Overview of potential procedural and participant-related confounds for neuroimaging of the resting state

PubMed Central

Duncan, Niall W.; Northoff, Georg

2013-01-01

Studies of intrinsic brain activity in the resting state have become increasingly common. A productive discussion of what analysis methods are appropriate, of the importance of physiologic correction and of the potential interpretations of results has been ongoing. However, less attention has been paid to factors other than physiologic noise that may confound resting-state experiments. These range from straightforward factors, such as ensuring that participants are all instructed in the same manner, to more obscure participant-related factors, such as body weight. We provide an overview of such potentially confounding factors, along with some suggested approaches for minimizing their impact. A particular theme that emerges from the overview is the range of systematic differences between types of study groups (e.g., between patients and controls) that may influence resting-state study results. PMID:22964258

Shape study of the N =Z nucleus 72Kr via β decay

NASA Astrophysics Data System (ADS)

Briz, J. A.; Nácher, E.; Borge, M. J. G.; Algora, A.; Rubio, B.; Dessagne, Ph.; Maira, A.; Cano-Ott, D.; Courtin, S.; Escrig, D.; Fraile, L. M.; Gelletly, W.; Jungclaus, A.; Le Scornet, G.; Maréchal, F.; Miehé, Ch.; Poirier, E.; Poves, A.; Sarriguren, P.; Taín, J. L.; Tengblad, O.

2015-11-01

The β decay of the N =Z nucleus 72Kr has been studied with the total absorption spectroscopy technique at ISOLDE (CERN). A total B (GT) =0.79 (4 ) gA2/4 π has been found up to an excitation energy of 2.7 MeV. The B (GT) distribution obtained is compared with predictions from state-of-the-art theoretical calculations to learn about the ground state deformation of 72Kr. Although a dominant oblate deformation is suggested by direct comparison with quasiparticle random phase approximation (QRPA) calculations, beyond-mean-field and shell-model calculations favor a large oblate-prolate mixing in the ground state.

Tribological studies of a Zr-based bulk metallic glass with different states

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiang, Feng; Qu, Jun; Fan, Guojiang

The tribological characteristics of a bulk-metallic glass (BMG) Zr52.5Cu17.9Ni14.6Al10.0Ti5.0 (Vit 105) with different states have been studied. Friction and wear tests were conducted using a ball-on-flat reciprocating sliding apparatus against AISI E52100 bearing steel under dry condition. The observed wear resistance in an ascending order is deformed, crept, relaxed, and as-cast. Results suggested that the wear process of BMG alloys involved abrasion, adhesion, and oxidation. The differences in hardness, free volume, and embrittlement at different states significantly affected the friction and wear behaviors of the BMG alloys.

Resonant photoemission spectroscopic studies of SnO2 thin films

NASA Astrophysics Data System (ADS)

Kumar, Sunil; Chauhan, R. S.; Panchal, Gyanendra; Singh, C. P.; Dar, Tanveer A.; Phase, D. M.; Choudhary, R. J.

2017-09-01

We report the structural and electronic properties of single phase, polycrystalline rutile tetragonal SnO2 thin film grown on Si (100) substrate by pulsed laser deposition technique. X-ray photoelectron and resonant photoemission spectroscopic (RPES) studies divulge that Sn is present in 4+ (˜91%) valence state with a very small involvement of 2+ (˜9%) valence state at the surface. Valence band spectrum of the film shows prominent contribution due to the Sn4+ valence state. RPES measurements were performed in the Sn 4d→5p photo absorption region. This study shows that O-2p, Sn-5s, and Sn-5p partial density of states are the main contributions to the valence band of this material. The resonance behavior of these three contributions has been analyzed. Constant initial state versus photon energy plots suggest that the low binding energy feature at ˜2.8 eV results from the hybridization of the O-2p and mixed valence states of Sn, while remaining features at higher binding energies are due to the hybridization between O-2p (bonding) orbitals and Sn4+ valence state.

Two pathways to self-forgiveness: A hedonic path via self-compassion and a eudaimonic path via the reaffirmation of violated values.

PubMed

Woodyatt, Lydia; Wenzel, Michael; Ferber, Matthew

2017-09-01

Self-forgiveness is often measured as a hedonic end-state, as the presence of positive affect and the absence of negative affect towards the self following a wrongdoing. However, self-forgiveness is also referred to as a difficult process. Self-forgiveness as a process of accepting responsibility and working through one's wrongdoing is a substantially un-hedonic - it is likely to be uncomfortable and at times painful. In this study, we examine two pathways to self-forgiveness: a hedonic focused pathway (via self-compassion) and a eudaimonic pathway (via reaffirmation of transgressed values). Across two studies, the data suggest that following interpersonal transgressions, self-compassion reduces self-punitiveness and increases end-state self-forgiveness (Study 1) via a reduction in perceived stigma (Study 2). In contrast, value reaffirmation increases the process of genuine self-forgiveness and reduces defensiveness (Study 1) via increased concern for shared group values (Study 2), in turn increasing desire to reconcile (Study 1), and amend-making and end-state self-forgiveness 1 week following the intervention (Study 2). The results suggest that both pathways can lead to self-forgiveness; however, following a transgression, self-forgiveness via a eudaimonic pathway offers greater promise for meeting the needs of both offenders and victims. © 2017 The British Psychological Society.

The development of children's prelife reasoning: evidence from two cultures.

PubMed

Emmons, Natalie A; Kelemen, Deborah

2014-01-01

Two studies investigated children's reasoning about their mental and bodily states during the time prior to biological conception-"prelife." By exploring prelife beliefs in 5- to 12-year-olds (N = 283) from two distinct cultures (urban Ecuadorians, rural indigenous Shuar), the studies aimed to uncover children's untutored intuitions about the essential features of persons. Results showed that with age, children judged fewer mental and bodily states to be functional during prelife. However, children from both cultures continued to privilege the functionality of certain mental states (i.e., emotions, desires) relative to bodily states (i.e., biological, psychobiological, perceptual states). Results converge with afterlife research and suggest that there is an unlearned cognitive tendency to view emotions and desires as the eternal core of personhood. © 2014 The Authors. Child Development © 2014 Society for Research in Child Development, Inc.

Observation of autoionization in O 2 by an electron-electron coincidence method

NASA Astrophysics Data System (ADS)

Doering, J. P.; Yang, J.; Cooper, J. W.

1995-01-01

A strong transition to an autoionizing stata has been observed in O 2 at 16.83 ± 0.11 eV by means of a new electron-electron conincidence method. The method uses the fact that electrons arising from autoionizing states appear at a constant energy loss corresponding to the excitation energy of the autoionizing state rather than at a constant ionization potential as do electrons produced by direct ionization. Comparison of the present data with previous photoionization studies suggests that the autoionizing O 2 state is the same state deduced to be responsible for abnormal vibrational intensities in the O 2+X 2Πg ground state when 16.85 eV Ne(I) photons are used. These electron-electron coincidence experiments provide a direct new method for the study of autoionization produced by electron impact.

On Philanthropy.

ERIC Educational Resources Information Center

Payton, Robert L.

1985-01-01

The president of the Exxon Education Foundation suggests that the study of philanthropy and the philanthropic tradition should be incorporated into formal education in the United States, in public education, the undergraduate curriculum, and research. (MSE)

Kickoff to Conflict: A Sequence Analysis of Intra-State Conflict-Preceding Event Structures

PubMed Central

D'Orazio, Vito; Yonamine, James E.

2015-01-01

While many studies have suggested or assumed that the periods preceding the onset of intra-state conflict are similar across time and space, few have empirically tested this proposition. Using the Integrated Crisis Early Warning System's domestic event data in Asia from 1998–2010, we subject this proposition to empirical analysis. We code the similarity of government-rebel interactions in sequences preceding the onset of intra-state conflict to those preceding further periods of peace using three different metrics: Euclidean, Levenshtein, and mutual information. These scores are then used as predictors in a bivariate logistic regression to forecast whether we are likely to observe conflict in neither, one, or both of the states. We find that our model accurately classifies cases where both sequences precede peace, but struggles to distinguish between cases in which one sequence escalates to conflict and where both sequences escalate to conflict. These findings empirically suggest that generalizable patterns exist between event sequences that precede peace. PMID:25951105

Spectroscopic and theoretical investigations on intramolecular charge transfer phenomenon in 1-3-dioxolane derivative

NASA Astrophysics Data System (ADS)

Zhang, Zhiyong; Zhang, Zhongzhi; Luo, Yijing; Sun, Shanshan; Zhang, Guangqing

2018-02-01

High fluorescence quantum yield (FQY) and large Stokes shift (SS) cannot be easily achieved simultaneously by traditional PICT or TICT fluorescent probe. However, an 1-3-dioxolane derivative named 5-methyl-8,9-dihydro-5H-[1,3]dioxolo[4,5-b]carbazol-6(7H)-one (MDDCO) features both high FQY and large SS. The purpose of this study is to search the mechanism behind this phenomenon by theoretical method. Simulated structure changes and charge transfer suggest ICT process in MDDCO is similar to PLICT (Planarized Intramolecular Charge Transfer) process. Calculated UV-Vis spectra and fluorescence spectra show that PLICT-like state (S1 state) of MDDCO leads to large SS. Computed transient-absorption spectra and radiative decay rates indicate that PLICT-like state is key factor for high FQY of MDDCO. These findings suggest that PLICT-like state in 1,3-dioxolane derivatives can achieve both large SS and high FQY, which presents a new method for high-performance fluorescent probe design.

Ecosystem health: I. Measuring ecosystem health

NASA Astrophysics Data System (ADS)

Schaeffer, David J.; Herricks, Edwin E.; Kerster, Harold W.

1988-07-01

Ecosystem analysis has been advanced by an improved understanding of how ecosystems are structured and how they function. Ecology has advanced from an emphasis on natural history to consideration of energetics, the relationships and connections between species, hierarchies, and systems theory. Still, we consider ecosystems as entities with a distinctive character and individual characteristics. Ecosystem maintenance and preservation form the objective of impact analysis, hazard evaluation, and other management or regulation activities. In this article we explore an approach to ecosystem analysis which identifies and quantifies factors which define the condition or state of an ecosystem in terms of health criteria. We relate ecosystem health to human/nonhuman animal health and explore the difficulties of defining ecosystem health and suggest criteria which provide a functional definition of state and condition. We suggest that, as has been found in human/nonhuman animal health studies, disease states can be recognized before disease is of clinical magnitude. Example disease states for ecosystems are functionally defined and discussed, together with test systems for their early detection.

Does Compound Nucleus remember its Isospin- An Evidence from the Fission Widths

NASA Astrophysics Data System (ADS)

Garg, Swati; Jain, Ashok Kumar

2018-05-01

We present an evidence of isospin effects in nuclear fission by comparing the fission widths for reactions involving different isospin states of the same compound nucleus (CN). Yadrovsky [1] suggested this possibility in 1975. Yadrovsky obtained the fission widths for two reaction data sets, namely 206Pb(α,f) and 209Bi(p,f), both leading to same CN, and concluded that "a nucleus remembers the isospin value of the nuclear states leading to fission". We obtain the fission decay widths for both the T0 + ½ and T0 - ½ states of CN by using two appropriate reaction data sets. We then compare the fission widths for the two isospin states of CN. More specifically, we have chosen the combination of 206Pb(α,f) and 209Bi(p,f) same as presented in Yadrovsky's paper [1] in this study. A significant difference between the ratios of fission decay widths to total decay widths for different isospin values suggests that isospin plays an important role in fission.

Impact of 36 h of total sleep deprivation on resting-state dynamic functional connectivity.

PubMed

Xu, Huaze; Shen, Hui; Wang, Lubin; Zhong, Qi; Lei, Yu; Yang, Liu; Zeng, Ling-Li; Zhou, Zongtan; Hu, Dewen; Yang, Zheng

2018-06-01

Resting-state functional magnetic resonance imaging (fMRI) studies using static functional connectivity (sFC) measures have shown that the brain function is severely disrupted after long-term sleep deprivation (SD). However, increasing evidence has suggested that resting-state functional connectivity (FC) is dynamic and exhibits spontaneous fluctuation on a smaller timescale. The process by which long-term SD can influence dynamic functional connectivity (dFC) remains unclear. In this study, 37 healthy subjects participated in the SD experiment, and they were scanned both during rested wakefulness (RW) and after 36 h of SD. A sliding-window based approach and a spectral clustering algorithm were used to evaluate the effects of SD on dFC based on the 26 qualified subjects' data. The outcomes showed that time-averaging FC across specific regions as well as temporal properties of the FC states, such as the dwell time and transition probability, was strongly influenced after SD in contrast to the RW condition. Based on the occurrences of FC states, we further identified some RW-dominant states characterized by anti-correlation between the default mode network (DMN) and other cortices, and some SD-dominant states marked by significantly decreased thalamocortical connectivity. In particular, the temporal features of these FC states were negatively correlated with the correlation coefficients between the DMN and dorsal attention network (dATN) and demonstrated high potential in classification of sleep state (with 10-fold cross-validation accuracy of 88.6% for dwell time and 88.1% for transition probability). Collectively, our results suggested that the temporal properties of the FC states greatly account for changes in the resting-state brain networks following SD, which provides new insights into the impact of SD on the resting-state functional organization in the human brain. Copyright © 2017. Published by Elsevier B.V.

Estimating the Availability of Potential Homes for Unwanted Horses in the United States

PubMed Central

Weiss, Emily; Dolan, Emily D.; Mohan-Gibbons, Heather; Gramann, Shannon; Slater, Margaret R.

2017-01-01

Simple Summary There are approximately 200,000 unwanted horses annually in the United States. Many are shipped to slaughter, enter rescue facilities, or are held on federal lands. This study aimed to estimate a potential number of available homes for unwanted horses in order to examine broadly the viability of pursuing re-homing policies as an option for the thousands of unwanted horses in the U.S. The results of this survey suggest there could be an estimated 1.2 million homes who have both the perceived resources and desire to house an unwanted horse. This number exceeds the approximately 200,000 unwanted horses living each year in the United States. These data suggest that efforts to reduce unwanted horses could involve matching such horses with adoptive homes and enhancing opportunities to keep horses in the homes they already have. Abstract There are approximately 200,000 unwanted horses annually in the United States. This study aimed to better understand the potential homes for horses that need to be re-homed. Using an independent survey company through an Omnibus telephone (land and cell) survey, we interviewed a nationally projectable sample of 3036 adults (using both landline and cellular phone numbers) to learn of their interest and capacity to adopt a horse. Potential adopters with interest in horses with medical and/or behavioral problems and self-assessed perceived capacity to adopt, constituted 0.92% of the total sample. Extrapolating the results of this survey using U.S. Census data, suggests there could be an estimated 1.25 million households who have both the self-reported and perceived resources and desire to house an unwanted horse. This number exceeds the estimated number of unwanted horses living each year in the United States. This study points to opportunities and need to increase communication and support between individuals and organizations that have unwanted horses to facilitate re-homing with people in their community willing to adopt them. PMID:28726730

A Cultural Interpretation of a Social Studies Curriculum.

ERIC Educational Resources Information Center

Chilcott, John H.

Social studies documents were collected from teachers in the Tucson, Arizona area and examined using three theories of culture as a way to explore the interrelationships between social studies curriculum and United States society. Malinowski's functionalist position suggests that culture is composed of traits each of which provide a specific…

US acculturation, food intake, and obesity among Asian-Pacific hotel workers.

PubMed

Novotny, Rachel; Williams, Andrew E; Vinoya, Aleli C; Oshiro, Caryn E S; Vogt, Thomas M

2009-10-01

Both obesity and immigration continue to increase in the United States. Studies suggest that a transition in lifestyle patterns, such as food intake, may mediate the relationship between immigration and obesity. We examine obesity among hotel workers in relation to age, sex, race/ethnicity, and indicators of food intake, immigration, and acculturation. Four thousand five hundred thirty hotel workers in 30 hotels were studied from the first year of the Work, Weight and Wellness program, before intervention (during 2005-2006). Weight and height were measured, whereas race/ethnicity, language, education, immigration, acculturation, and food intake variables were assessed by questionnaire. The study included 43% male and 57% female hotel workers (mean age 44.4+/-11.3 years; 42% Filipino, 32% other Asian, 13% Pacific Islander, 9% white, 1% black/African American, and 3% other race/ethnicity). On average (mean value), 55% of participants were born outside the United States; 57% were overweight or obese (body mass index [BMI] >25). The BMI of those born in the United States was 1.3 higher than that of those born in another country, adjusting for sex and race/ethnicity. Intake of sweet drinks and meat was positively associated with BMI while intake of fruit was negatively associated with BMI. Age at arrival in United States ("generation") was negatively associated with BMI, whereas greater acculturation was positively associated with BMI. Food intake behaviors are probably related to place of birth, generation of migration to the United States, and acculturation. Direct measures of food intake added explanatory power to models, suggesting the importance of food intake to obesity. Further study of the influence of immigration, acculturation, and food intake on obesity using longitudinal study designs is warranted.

Are You Ready to Have Fun? The Spanish State Form of the State-Trait-Cheerfulness Inventory.

PubMed

López-Benítez, Raúl; Acosta, Alberto; Lupiáñez, Juan; Carretero-Dios, Hugo

2017-09-21

Although cheerfulness, seriousness, and bad mood as traits have been widely studied as the basis of sense of humor, data are scarce regarding the same dimensions as states. In this study, we adapted the state form of the State-Trait-Cheerfulness Inventory (STCI-S) into Spanish. At the same time, we empirically tested new predictions. We assessed 5 independent samples accounting for 1,029 participants (647 women) with ages ranging from 18 to 78 years. We confirmed the 3-dimensional structure as well as a strong measurement invariance between men and women. The internal consistency of the scale was satisfactory, the expected intercorrelations emerged, and the convergence between states and traits was corroborated. We also confirmed that the STCI-S's items were sensitive to affective changes in the environment. A longitudinal stability study of the state-trait dimensions using latent state-trait (LST) models revealed that all three trait measures capture mostly stable interindividual differences, with occasion-specific effects mainly in the state dimensions. Finally, we found that the STCI-S dimensions were related to state well-being. The results suggest that the STCI-S is a valid option for measuring the state basis of sense of humor in the Spanish population.

Field Guide to Soils. Earth Science Curriculum Project Pamphlet Series PS-2.

ERIC Educational Resources Information Center

Foth, Henry; Jacobs, Hyde S.

Discussed are the importance of soil to plant and animal life, the evolution of a soil profile, and the major kinds of soil in the United States. On a suggested field trip, students examine different kinds of soil profiles; they also measure soil acidity and water-holding capacity. Suggestions for further study are provided along with references…

Determining the Persuasiveness of Message Sidedness: A Prudent Note about Utilizing Research Summaries.

ERIC Educational Resources Information Center

Allen, Mike

1993-01-01

Responds to an analysis by D. O'Keefe (in the same issue of this journal) of a research study by the author. States that most of what O'Keefe suggests contains merit but that acceptance of the suggestions still generates a conclusion that two-sided refutational messages constitute the most persuasive form of message. (SR)

Properties influencing fat, oil, and grease deposit formation.

PubMed

Keener, Kevin M; Ducoste, Joel J; Holt, Leon M

2008-12-01

Fat, oil, and grease (FOG) deposits are the reported cause of 50 to 75% of sanitary sewer overflows in the United States, resulting in 1.8 X 10(6) m3 (500 mil. gal) of raw wastewater released into the environment annually. The objective of this research was to characterize the chemical and physical properties of FOG deposits. Twenty-three cities from around the United States contributed FOG samples for the study. The FOG deposits showed a wide range in yield strength (4 to 34 kPa), porosity (10 to 24%), and moisture content (10 to 60%), suggesting uncontrolled formation processes. A majority of these deposits display hard, sandstonelike texture, with distinct layering effects, suggesting a discontinuous formation process. The results found that 84% of FOG deposits contained high concentrations of saturated fatty acids and calcium, suggesting preferential accumulation.

Implementation of cargo MagLev in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rose, Chris R; Peterson, Dean E; Leung, Eddie M

2008-01-01

Numerous studies have been completed in the United States, but no commercial MagLev systems have been deployed. Outside the U.S., MagLev continues to attract funding for research, development and implementation. A brief review of recent global developments in MagLev technology is given followed by the status of MagLev in the U.S. The paper compares the cost of existing MagLev systems with other modes of transport, notes that the near-term focus of MagLev development in the U.S. should be for cargo, and suggests that future MagLev systems should be for very high speed cargo. The Los Angeles to Port of Losmore » Angeles corridor is suggested as a first site for implementation. The benefits of MagLev are described along with suggestions on how to obtain funding.« less

Correlation between Photovoltaic Performance and Interchain Ordering Induced Delocalization of Electronics States in Conjugated Polymer Blends.

PubMed

Chandrasekaran, Naresh; Gann, Eliot; Jain, Nakul; Kumar, Anshu; Gopinathan, Sreelekha; Sadhanala, Aditya; Friend, Richard H; Kumar, Anil; McNeill, Christopher R; Kabra, Dinesh

2016-08-10

In this paper we correlate the solar cell performance with bimolecular packing of donor:acceptor bulk heterojunction (BHJ) organic solar cells (OSCs), where interchain ordering of the donor molecule and its influence on morphology, optical properties, and charge carrier dynamics of BHJ solar cells are studied in detail. Solar cells that are fabricated using more ordered defect free 100% regioregular poly(3-hexylthiophene) (DF-P3HT) as the donor polymer show ca. 10% increase in the average power conversion efficiency (PCE) when compared to that of the solar cell fabricated using 92% regioregularity P3HT, referred to as rr-P3HT. EQE and UV-vis absorption spectrum show a clear increase in the 607 nm vibronic shoulder of the DF-P3HT blend suggesting better interchain ordering which was also reflected in the less Urbach energy (Eu) value for this system. The increase in ordering inside the blend has enhanced the hole-mobility which is calculated from the single carrier device J-V characteristics. Electroluminance (EL) studies on the DF-P3HT system showed a red-shifted peak when compared to rr-P3HT-based devices suggesting low CT energy states in DF-P3HT. The morphologies of the blend films are studied using AFM and grazing-incidence wide-angle X-ray scattering (GIWAXS) suggesting increase in the roughness and phase segregation which could enhance the internal scattering of the light inside the device and improvement in the crystallinity along alkyl and π-stacking direction. Hence, higher PCE, lower Eu, red-shifted EL emission, high hole-mobility, and better crystallinity suggest improved interchain ordering has facilitated a more delocalized HOMO state in DF-P3HT-based BHJ solar cells.

Ultrafast excited-state dynamics of RNA and DNA C tracts

NASA Astrophysics Data System (ADS)

Cohen, Boiko; Larson, Matthew H.; Kohler, Bern

2008-06-01

The excited-state dynamics of the RNA homopolymer of cytosine and of the 18-mer (dC) 18 were studied by steady-state and time-resolved absorption and emission spectroscopy. At pH 6.8, excitation of poly(rC) by a femtosecond UV pump pulse produces excited states that decay up to one order of magnitude more slowly than the excited states formed in the mononucleotide cytidine 5'-monophosphate under the same conditions. Even slower relaxation is observed for the hemiprotonated, self-associated form of poly(rC), which is stable at acidic pH. Transient absorption and time-resolved fluorescence signals for (dC) 18 at pH 6.8 are similar to ones observed for poly(rC) near pH 4, indicating that hemiprotonated structures are found in DNA C tracts at neutral pH. In both systems, there is evidence for two kinds of emitting states with lifetimes of ˜100 ps and slightly more than 1 ns. The former states are responsible for the bulk of emission from the hemiprotonated structures. Evidence suggests that slow electronic relaxation in these self-complexes is the result of vertical base stacking. The similar signals from RNA and DNA C tracts suggest a common base-stacked structure, which may be identical with that of i-motif DNA.

Association between heart rate variability and fluctuations in resting-state functional connectivity

PubMed Central

Chang, Catie; Metzger, Coraline D.; Glover, Gary H.; Duyn, Jeff H.; Heinze, Hans-Jochen; Walter, Martin

2012-01-01

Functional connectivity has been observed to fluctuate across the course of a resting state scan, though the origins and functional relevance of this phenomenon remain to be shown. The present study explores the link between endogenous dynamics of functional connectivity and autonomic state in an eyes-closed resting condition. Using a sliding window analysis on resting state fMRI data from 35 young, healthy male subjects, we examined how heart rate variability (HRV) covaries with temporal changes in whole-brain functional connectivity with seed regions previously described to mediate effects of vigilance and arousal (amygdala and dorsal anterior cingulate cortex; dACC). We identified a set of regions, including brainstem, thalamus, putamen, and dorsolateral prefrontal cortex, that became more strongly coupled with the dACC and amygdala seeds during states of elevated HRV. Effects differed between high and low frequency components of HRV, suggesting specific contributions of parasympathetic and sympathetic tone on individual connections. Furthermore, dynamics of functional connectivity could be separated from those primarily related to BOLD signal fluctuations. The present results contribute novel information about the neural basis of transient changes of autonomic nervous system states, and suggest physiological and psychological components of the recently observed non-stationarity in resting state functional connectivity. PMID:23246859

Assessing the Effectiveness of On-Farm and Abattoir Interventions in Reducing Pig Meat-Borne Salmonellosis within E.U. Member States.

PubMed

Hill, Andrew A; Simons, Robin L; Swart, Arno N; Kelly, Louise; Hald, Tine; Snary, Emma L

2016-03-01

As part of the evidence base for the development of national control plans for Salmonella spp. in pigs for E.U. Member States, a quantitative microbiological risk assessment was funded to support the scientific opinion required by the EC from the European Food Safety Authority. The main aim of the risk assessment was to assess the effectiveness of interventions implemented on-farm and at the abattoir in reducing human cases of pig meat-borne salmonellosis, and how the effects of these interventions may vary across E.U. Member States. Two case study Member States have been chosen to assess the effect of the interventions investigated. Reducing both breeding herd and slaughter pig prevalence were effective in achieving reductions in the number of expected human illnesses in both case study Member States. However, there is scarce evidence to suggest which specific on-farm interventions could achieve consistent reductions in either breeding herd or slaughter pig prevalence. Hypothetical reductions in feed contamination rates were important in reducing slaughter pig prevalence for the case study Member State where prevalence of infection was already low, but not for the high-prevalence case study. The most significant reductions were achieved by a 1- or 2-log decrease of Salmonella contamination of the carcass post-evisceration; a 1-log decrease in average contamination produced a 90% reduction in human illness. The intervention analyses suggest that abattoir intervention may be the most effective way to reduce human exposure to Salmonella spp. However, a combined farm/abattoir approach would likely have cumulative benefits. On-farm intervention is probably most effective at the breeding-herd level for high-prevalence Member States; once infection in the breeding herd has been reduced to a low enough level, then feed and biosecurity measures would become increasingly more effective. © 2016 Society for Risk Analysis.

The inverse-trans-influence in tetravalent lanthanide and actinide bis(carbene) complexes

NASA Astrophysics Data System (ADS)

Gregson, Matthew; Lu, Erli; Mills, David P.; Tuna, Floriana; McInnes, Eric J. L.; Hennig, Christoph; Scheinost, Andreas C.; McMaster, Jonathan; Lewis, William; Blake, Alexander J.; Kerridge, Andrew; Liddle, Stephen T.

2017-02-01

Across the periodic table the trans-influence operates, whereby tightly bonded ligands selectively lengthen mutually trans metal-ligand bonds. Conversely, in high oxidation state actinide complexes the inverse-trans-influence operates, where normally cis strongly donating ligands instead reside trans and actually reinforce each other. However, because the inverse-trans-influence is restricted to high-valent actinyls and a few uranium(V/VI) complexes, it has had limited scope in an area with few unifying rules. Here we report tetravalent cerium, uranium and thorium bis(carbene) complexes with trans C=M=C cores where experimental and theoretical data suggest the presence of an inverse-trans-influence. Studies of hypothetical praseodymium(IV) and terbium(IV) analogues suggest the inverse-trans-influence may extend to these ions but it also diminishes significantly as the 4f orbitals are populated. This work suggests that the inverse-trans-influence may occur beyond high oxidation state 5f metals and hence could encompass mid-range oxidation state actinides and lanthanides. Thus, the inverse-trans-influence might be a more general f-block principle.

The inverse-trans-influence in tetravalent lanthanide and actinide bis(carbene) complexes.

PubMed

Gregson, Matthew; Lu, Erli; Mills, David P; Tuna, Floriana; McInnes, Eric J L; Hennig, Christoph; Scheinost, Andreas C; McMaster, Jonathan; Lewis, William; Blake, Alexander J; Kerridge, Andrew; Liddle, Stephen T

2017-02-03

Across the periodic table the trans-influence operates, whereby tightly bonded ligands selectively lengthen mutually trans metal-ligand bonds. Conversely, in high oxidation state actinide complexes the inverse-trans-influence operates, where normally cis strongly donating ligands instead reside trans and actually reinforce each other. However, because the inverse-trans-influence is restricted to high-valent actinyls and a few uranium(V/VI) complexes, it has had limited scope in an area with few unifying rules. Here we report tetravalent cerium, uranium and thorium bis(carbene) complexes with trans C=M=C cores where experimental and theoretical data suggest the presence of an inverse-trans-influence. Studies of hypothetical praseodymium(IV) and terbium(IV) analogues suggest the inverse-trans-influence may extend to these ions but it also diminishes significantly as the 4f orbitals are populated. This work suggests that the inverse-trans-influence may occur beyond high oxidation state 5f metals and hence could encompass mid-range oxidation state actinides and lanthanides. Thus, the inverse-trans-influence might be a more general f-block principle.

The inverse-trans-influence in tetravalent lanthanide and actinide bis(carbene) complexes

PubMed Central

Gregson, Matthew; Lu, Erli; Mills, David P.; Tuna, Floriana; McInnes, Eric J. L.; Hennig, Christoph; Scheinost, Andreas C.; McMaster, Jonathan; Lewis, William; Blake, Alexander J.; Kerridge, Andrew; Liddle, Stephen T.

2017-01-01

Across the periodic table the trans-influence operates, whereby tightly bonded ligands selectively lengthen mutually trans metal–ligand bonds. Conversely, in high oxidation state actinide complexes the inverse-trans-influence operates, where normally cis strongly donating ligands instead reside trans and actually reinforce each other. However, because the inverse-trans-influence is restricted to high-valent actinyls and a few uranium(V/VI) complexes, it has had limited scope in an area with few unifying rules. Here we report tetravalent cerium, uranium and thorium bis(carbene) complexes with trans C=M=C cores where experimental and theoretical data suggest the presence of an inverse-trans-influence. Studies of hypothetical praseodymium(IV) and terbium(IV) analogues suggest the inverse-trans-influence may extend to these ions but it also diminishes significantly as the 4f orbitals are populated. This work suggests that the inverse-trans-influence may occur beyond high oxidation state 5f metals and hence could encompass mid-range oxidation state actinides and lanthanides. Thus, the inverse-trans-influence might be a more general f-block principle. PMID:28155857

Indicators of ecosystem function identify alternate states in the sagebrush steppe.

PubMed

Kachergis, Emily; Rocca, Monique E; Fernandez-Gimenez, Maria E

2011-10-01

Models of ecosystem change that incorporate nonlinear dynamics and thresholds, such as state-and-transition models (STMs), are increasingly popular tools for land management decision-making. However, few models are based on systematic collection and documentation of ecological data, and of these, most rely solely on structural indicators (species composition) to identify states and transitions. As STMs are adopted as an assessment framework throughout the United States, finding effective and efficient ways to create data-driven models that integrate ecosystem function and structure is vital. This study aims to (1) evaluate the utility of functional indicators (indicators of rangeland health, IRH) as proxies for more difficult ecosystem function measurements and (2) create a data-driven STM for the sagebrush steppe of Colorado, USA, that incorporates both ecosystem structure and function. We sampled soils, plant communities, and IRH at 41 plots with similar clayey soils but different site histories to identify potential states and infer the effects of management practices and disturbances on transitions. We found that many IRH were correlated with quantitative measures of functional indicators, suggesting that the IRH can be used to approximate ecosystem function. In addition to a reference state that functions as expected for this soil type, we identified four biotically and functionally distinct potential states, consistent with the theoretical concept of alternate states. Three potential states were related to management practices (chemical and mechanical shrub treatments and seeding history) while one was related only to ecosystem processes (erosion). IRH and potential states were also related to environmental variation (slope, soil texture), suggesting that there are environmental factors within areas with similar soils that affect ecosystem dynamics and should be noted within STMs. Our approach generated an objective, data-driven model of ecosystem dynamics for rangeland management. Our findings suggest that the IRH approximate ecosystem processes and can distinguish between alternate states and communities and identify transitions when building data-driven STMs. Functional indicators are a simple, efficient way to create data-driven models that are consistent with alternate state theory. Managers can use them to improve current model-building methods and thus apply state-and-transition models more broadly for land management decision-making.

Photodissociation Dynamics of Vinyl Cyanide Studied by Chirped-Pulse Millimeter-Wave Spectroscopy of HCN and HNC Products

NASA Astrophysics Data System (ADS)

Prozument, Kirill; Shaver, Rachel G.; Baraban, Joshua H.; Park, G. Barratt; Suits, Arthur G.; Muenter, John S.; Field, Robert W.

2013-06-01

Vinyl cyanide 193 nm photodissociation has been studied using Chirped-Pulse Millimeter-Wave (CPmmW) spectroscopy. J = 0 - 1 transitions of more than 30 vibrationally excited states of the HCN and HNC products have been recorded and assigned within the 7 GHz wide chirp range. Bending excitations of HCN up to v_2 = 14, leading toward the HCN leftrightarrow HNC isomerization transition state, are detected and interpreted in terms of their electric quadrupole, (eQq)_{N}, and rotational, B_v, constants. The photolysis reaction transition states were probed using both normal vinyl cyanide, CH_2=CHCN, and its singly-deuterated isotopologue, CH_2=CDCN. The observed difference in the vibrational population distribution (VPD) obtained from the integrated intensities of the HCN and DCN products from the CH_2=CHCN vs. CH_2=CDCN photolysis reactions, suggests the relative unimportance of the three-center elimination mechanism for HCN production. On the other hand, the similarity in the observed VPD and overall intensities of HCN from CH_2=CHCN and CH_2=CDCN photolysis suggests four-center elimination as the major mechanism leading to the HCN product. Additional J - (J + 1) transitions would be required to characterize both the vibrational and the rotational state distributions of the products, which would permit more complete characterization of the transition state(s). The authors thank the Department of Energy, and KP thanks the ACS Petroleum Research Fund for their support of this work.

Translating Disparities Research to Policy: A Qualitative Study of State Mental Health Policymakers' Perceptions of Mental Health Care Disparities Report Cards

PubMed Central

Valentine, Anne; DeAngelo, Darcie; Alegría, Margarita; Cook, Benjamin L.

2014-01-01

Report cards have been used to increase accountability and quality of care in health care settings, and to improve state infrastructure for providing quality mental health care services. However, to date, report cards have not been used to compare states on racial/ethnic disparities in mental health care. This qualitative study examines reactions of mental health care policymakers to a proposed mental health care disparities report card generated from population-based survey data of mental health and mental health care utilization. We elicited feedback about the content, format, and salience of the report card. Interviews were conducted with nine senior advisors to state policymakers and one policy director of a national non-governmental organization from across the U.S. Four primary themes emerged: fairness in state-by-state comparisons; disconnect between the goals and language of policymakers and researchers; concerns about data quality and; targeted suggestions from policymakers. Participant responses provide important information that can contribute to making evidence-based research more accessible to policymakers. Further, policymakers suggested ways to improve the structure and presentation of report cards to make them more accessible to policymakers and to foster equity considerations during the implementation of new health care legislation. To reduce mental health care disparities, effort is required to facilitate understanding between researchers and relevant stakeholders about research methods, standards for interpretation of research-based evidence and its use in evaluating policies aimed at ameliorating disparities. PMID:25383993

The Influence of Emotional State and Pictorial Cues on Perceptual Judgments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kimberly R. Raddatz; Abigail Werth; Tuan Q. Tran

2007-10-01

Perspective displays (e.g., CDTI) are commonly used as decision aids in environments characterized by periods of high emotional arousal (e.g., terrain enhanced primary flight displays). However, little attention has been devoted to understanding how emotional state, independently or in conjunction with other perceptual factors (e.g., pictorial depth cues), can impact perceptual judgments. Preliminary research suggests that induced emotional state (positive or negative) adversely impacts size comparisons in perspective displays (Tran & Raddatz, 2006). This study further investigated how size comparisons are affected by emotional state and pictorial depth cues while attenuating the limitations of the Tran & Raddatz (2006) study.more » Results confirmed that observers do make slower judgments under induced emotional state. However, observers under negative emotional state showed higher sensitivity (d’) and required more evidence to respond that a size difference exists (response bias) than observers under positive emotional state. Implications for display design and human performance are discussed.« less

The functional implications of motor, cognitive, psychiatric, and social problem-solving states in Huntington's disease.

PubMed

Van Liew, Charles; Gluhm, Shea; Goldstein, Jody; Cronan, Terry A; Corey-Bloom, Jody

2013-01-01

Huntington's disease (HD) is a genetic, neurodegenerative disorder characterized by motor, cognitive, and psychiatric dysfunction. In HD, the inability to solve problems successfully affects not only disease coping, but also interpersonal relationships, judgment, and independent living. The aim of the present study was to examine social problem-solving (SPS) in well-characterized HD and at-risk (AR) individuals and to examine its unique and conjoint effects with motor, cognitive, and psychiatric states on functional ratings. Sixty-three participants, 31 HD and 32 gene-positive AR, were included in the study. Participants completed the Social Problem-Solving Inventory-Revised: Long (SPSI-R:L), a 52-item, reliable, standardized measure of SPS. Items are aggregated under five scales (Positive, Negative, and Rational Problem-Solving; Impulsivity/Carelessness and Avoidance Styles). Participants also completed the Unified Huntington's Disease Rating Scale functional, behavioral, and cognitive assessments, as well as additional neuropsychological examinations and the Symptom Checklist-90-Revised (SCL-90R). A structural equation model was used to examine the effects of motor, cognitive, psychiatric, and SPS states on functionality. The multifactor structural model fit well descriptively. Cognitive and motor states uniquely and significantly predicted function in HD; however, neither psychiatric nor SPS states did. SPS was, however, significantly related to motor, cognitive, and psychiatric states, suggesting that it may bridge the correlative gap between psychiatric and cognitive states in HD. SPS may be worth assessing in conjunction with the standard gamut of clinical assessments in HD. Suggestions for future research and implications for patients, families, caregivers, and clinicians are discussed.

How Nonpartisan Ballot Design Conceals Partisanship: A Survey Experiment of School Board Members in Two States

ERIC Educational Resources Information Center

Crawford, Evan

2017-01-01

Studies suggest that between one-fourth and one-third of localities elect their leaders on partisan ballots. Does the presence of a party label on the ballot affect the level of partisanship in local office? I leverage the fact that within select states, school boards vary as to whether their members are elected on partisan or nonpartisan ballots.…

The Incidence and Wage Consequences of Home-Based Work in the United States, 1980-2000

ERIC Educational Resources Information Center

Oettinger, Gerald S.

2011-01-01

This study documents the rapid growth in home-based wage and salary employment and the sharp decline in the home-based wage penalty in the United States between 1980 and 2000. These twin patterns, observed for both men and women in most occupation groups, suggest that employer costs of providing home-based work arrangements have decreased.…

Relationship between the Quality of Educational Facilities, School Climate, and School Safety of High School Tenth Graders in the United States

ERIC Educational Resources Information Center

Bell, Darnell Brushawn

2011-01-01

The purpose of the study was to understand the relationships among facility conditions, school climate, and school safety of high school tenth graders in the United States. Previous research on the quality of educational facilities influence on student achievement has varied. Recent research has suggested that the quality of educational facilities…

24 CFR 3282.303 - State plan-suggested provisions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false State plan-suggested provisions. 3282.303 Section 3282.303 Housing and Urban Development Regulations Relating to Housing and Urban... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS State...

The effect of alcoholic beverage excise tax on alcohol-attributable injury mortalities.

PubMed

Son, Chong Hwan; Topyan, Kudret

2011-04-01

This study examines the effect of state excise taxes on different types of alcoholic beverages (spirits, wine, and beer) on alcohol-attributable injury mortalities--deaths caused by motor vehicle accidents, suicides, homicides, and falls--in the United States between 1995 and 2004, using state-level panel data. There is evidence that injury deaths attributable to alcohol respond differently to changes in state excise taxes on alcohol-specific beverages. This study examines the direct relationship between injury deaths and excise taxes without testing the degree of the association between excise taxes and alcohol consumption. The study finds that beer taxes are negatively related to motor vehicle accident mortality, while wine taxes are negatively associated with suicides and falls. The positive coefficient of the spirit taxes on falls implies a substitution effect between spirits and wine, suggesting that an increase in spirit tax will cause spirit buyers to purchase more wine. This study finds no evidence of a relationship between homicides and state excise taxes on alcohol. Thus, the study concludes that injury deaths attributable to alcohol respond differently to the excise taxes on different types of alcoholic beverages.

The TIMSS Videotape Study.

ERIC Educational Resources Information Center

Stigler, James W.; Hiebert, James

1998-01-01

As part of the Third International Mathematics and Science Study (TIMSS), videotapes of classroom instruction were collected from 231 eighth-grade mathematics classrooms in Germany, the United States, and Japan. Findings suggest that written reports about teaching disseminated to teachers may have little effect on classroom practices. (SLD)

A study of the cross-correlation and time lag in black hole X-ray binary XTE J1859+226

NASA Astrophysics Data System (ADS)

Pei, Songpeng; Ding, Guoqiang; Li, Zhibing; Lei, Yajuan; Yuen, Rai; Qu, Jinlu

2017-07-01

With Rossi X-ray Timing Explorer (RXTE) data, we systematically study the cross-correlation and time lag in all spectral states of black hole X-ray binary (BHXB) XTE J1859+226 in detail during its entire 1999-2000 outburst that lasted for 166 days. Anti-correlations and positive correlations and their respective soft and hard X-ray lags are only detected in the first 100 days of the outburst when the luminosity is high. This suggests that the cross-correlations may be related to high luminosity. Positive correlations are detected in every state of XTE J1859+226, viz., hard state, hard-intermediate state (HIMS), soft-intermediate state (SIMS) and soft state. However, anti-correlations are only detected in HIMS and SIMS, anti-correlated hard lags are only detected in SIMS, while anti-correlated soft lags are detected in both HIMS and SIMS. Moreover, the ratio of the observations with anti-correlated soft lags to hard lags detected in XTE J1859+226 is significantly different from that in neutron star low-mass X-ray binaries (NS LMXBs). So far, anti-correlations are never detected in the soft state of BHXBs but detected in every branch or state of NS LMXBs. This may be due to the origin of soft seed photons in BHXBs is confined to the accretion disk and, for NS LMXBs, from both accretion disk and the surface of the NS. We notice that the timescale of anti-correlated time lags detected in XTE J1859+226 is similar with that of other BHXBs and NS LMXBs. We suggest that anti-correlated soft lag detected in BHXB may result from fluctuation in the accretion disk as well as NS LMXB.

"Time for dabs": Analyzing Twitter data on marijuana concentrates across the U.S.

PubMed

Daniulaityte, Raminta; Nahhas, Ramzi W; Wijeratne, Sanjaya; Carlson, Robert G; Lamy, Francois R; Martins, Silvia S; Boyer, Edward W; Smith, G Alan; Sheth, Amit

2015-10-01

Media reports suggest increasing popularity of marijuana concentrates ("dabs"; "earwax"; "budder"; "shatter; "butane hash oil") that are typically vaporized and inhaled via a bong, vaporizer or electronic cigarette. However, data on the epidemiology of marijuana concentrate use remain limited. This study aims to explore Twitter data on marijuana concentrate use in the U.S. and identify differences across regions of the country with varying cannabis legalization policies. Tweets were collected between October 20 and December 20, 2014, using Twitter's streaming API. Twitter data filtering framework was available through the eDrugTrends platform. Raw and adjusted percentages of dabs-related tweets per state were calculated. A permutation test was used to examine differences in the adjusted percentages of dabs-related tweets among U.S. states with different cannabis legalization policies. eDrugTrends collected a total of 125,255 tweets. Almost 22% (n=27,018) of these tweets contained identifiable state-level geolocation information. Dabs-related tweet volume for each state was adjusted using a general sample of tweets to account for different levels of overall tweeting activity for each state. Adjusted percentages of dabs-related tweets were highest in states that allowed recreational and/or medicinal cannabis use and lowest in states that have not passed medical cannabis use laws. The differences were statistically significant. Twitter data suggest greater popularity of dabs in the states that legalized recreational and/or medical use of cannabis. The study provides new information on the epidemiology of marijuana concentrate use and contributes to the emerging field of social media analysis for drug abuse research. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

“Time for dabs”: Analyzing Twitter data on marijuana concentrates across the U.S.

PubMed Central

Daniulaityte, Raminta; Nahhas, Ramzi W.; Wijeratne, Sanjaya; Carlson, Robert G.; Lamy, Francois R.; Martins, Silvia S.; Boyer, Edward W.; Smith, G. Alan; Sheth, Amit

2015-01-01

Aims Media reports suggest increasing popularity of marijuana concentrates (“dabs”; “earwax”; “budder”; “shatter; “butane hash oil”) that are typically vaporized and inhaled via a bong, vaporizer or electronic cigarette. However, data on the epidemiology of marijuana concentrate use remain limited. This study aims to explore Twitter data on marijuana concentrate use in the U.S. and identify differences across regions of the country with varying cannabis legalization policies. Methods Tweets were collected between October 20 and December 20, 2014, using Twitter's streaming API. Twitter data filtering framework was available through the eDrugTrends platform. Raw and adjusted percentages of dabs-related tweets per state were calculated. A permutation test was used to examine differences in the adjusted percentages of dabs-related tweets among U.S. states with different cannabis legalization policies. Results eDrugTrends collected a total of 125,255 tweets. Almost 22% (n=27,018) of these tweets contained identifiable state-level geolocation information. Dabs-related tweet volume for each state was adjusted using a general sample of tweets to account for different levels of overall tweeting activity for each state. Adjusted percentages of dabs-related tweets were highest in states that allowed recreational and/or medicinal cannabis use and lowest in states that have not passed medical cannabis use laws. The differences were statistically significant. Conclusions Twitter data suggest greater popularity of dabs in the states that legalized recreational and/or medical use of cannabis. The study provides new information on the epidemiology of marijuana concentrate use and contributes to the emerging field of social media analysis for drug abuse research. PMID:26338481

Ab Initio Study of Electronic Excitation Effects on SrTiO 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao, Shijun; Zhang, Yanwen; Weber, William J.

Interaction of energetic ions or lasers with solids often induces electronic excitations that may modify material properties significantly. In this study, effects of electronic excitations on strontium titanate SrTiO 3 (STO) are investigated based on first-principles calculations. The lattice structure, electronic properties, lattice vibrational frequencies, and dynamical stabilities are studied in detail. The results suggest that electronic excitation induces charge redistribution that is mainly observed in Ti–O bonds. The electronic band gap increases with increasing electronic excitation, as excitation mainly induces depopulation of Ti 3d states. Phonon analysis indicates that there is a large phonon band gap induced by electronicmore » excitation because of the changes in the vibrational properties of Ti and O atoms. In addition, a new peak appears in the phonon density of states with imaginary frequencies, an indication of lattice instability. Further dynamics simulations confirm that STO undergoes transition to an amorphous structure under strong electronic excitations. In conclusion, the optical properties of STO under electronic excitation are consistent with the evolution of atomic and electronic structures, which suggests a possibility to probe the properties of STO in nonequilibrium state using optical measurement.« less

Ab Initio Study of Electronic Excitation Effects on SrTiO 3

DOE PAGES

Zhao, Shijun; Zhang, Yanwen; Weber, William J.

2017-11-14

Interaction of energetic ions or lasers with solids often induces electronic excitations that may modify material properties significantly. In this study, effects of electronic excitations on strontium titanate SrTiO 3 (STO) are investigated based on first-principles calculations. The lattice structure, electronic properties, lattice vibrational frequencies, and dynamical stabilities are studied in detail. The results suggest that electronic excitation induces charge redistribution that is mainly observed in Ti–O bonds. The electronic band gap increases with increasing electronic excitation, as excitation mainly induces depopulation of Ti 3d states. Phonon analysis indicates that there is a large phonon band gap induced by electronicmore » excitation because of the changes in the vibrational properties of Ti and O atoms. In addition, a new peak appears in the phonon density of states with imaginary frequencies, an indication of lattice instability. Further dynamics simulations confirm that STO undergoes transition to an amorphous structure under strong electronic excitations. In conclusion, the optical properties of STO under electronic excitation are consistent with the evolution of atomic and electronic structures, which suggests a possibility to probe the properties of STO in nonequilibrium state using optical measurement.« less

Potential energy surfaces and reaction dynamics of polyatomic molecules

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chang, Yan-Tyng

A simple empirical valence bond (EVB) model approach is suggested for constructing global potential energy surfaces for reactions of polyatomic molecular systems. This approach produces smooth and continuous potential surfaces which can be directly utilized in a dynamical study. Two types of reactions are of special interest, the unimolecular dissociation and the unimolecular isomerization. For the first type, the molecular dissociation dynamics of formaldehyde on the ground electronic surface is investigated through classical trajectory calculations on EVB surfaces. The product state distributions and vector correlations obtained from this study suggest very similar behaviors seen in the experiments. The intramolecular hydrogenmore » atom transfer in the formic acid dimer is an example of the isomerization reaction. High level ab initio quantum chemistry calculations are performed to obtain optimized equilibrium and transition state dimer geometries and also the harmonic frequencies.« less

Task vs. rest-different network configurations between the coactivation and the resting-state brain networks.

PubMed

Di, Xin; Gohel, Suril; Kim, Eun H; Biswal, Bharat B

2013-01-01

There is a growing interest in studies of human brain networks using resting-state functional magnetic resonance imaging (fMRI). However, it is unclear whether and how brain networks measured during the resting-state exhibit comparable properties to brain networks during task performance. In the present study, we investigated meta-analytic coactivation patterns among brain regions based upon published neuroimaging studies, and compared the coactivation network configurations with those in the resting-state network. The strength of resting-state functional connectivity between two regions were strongly correlated with the coactivation strength. However, the coactivation network showed greater global efficiency, smaller mean clustering coefficient, and lower modularity compared with the resting-state network, which suggest a more efficient global information transmission and between system integrations during task performing. Hub shifts were also observed within the thalamus and the left inferior temporal cortex. The thalamus and the left inferior temporal cortex exhibited higher and lower degrees, respectively in the coactivation network compared with the resting-state network. These results shed light regarding the reconfiguration of the brain networks between task and resting-state conditions, and highlight the role of the thalamus in change of network configurations in task vs. rest.

Task vs. rest—different network configurations between the coactivation and the resting-state brain networks

PubMed Central

Di, Xin; Gohel, Suril; Kim, Eun H.; Biswal, Bharat B.

2013-01-01

There is a growing interest in studies of human brain networks using resting-state functional magnetic resonance imaging (fMRI). However, it is unclear whether and how brain networks measured during the resting-state exhibit comparable properties to brain networks during task performance. In the present study, we investigated meta-analytic coactivation patterns among brain regions based upon published neuroimaging studies, and compared the coactivation network configurations with those in the resting-state network. The strength of resting-state functional connectivity between two regions were strongly correlated with the coactivation strength. However, the coactivation network showed greater global efficiency, smaller mean clustering coefficient, and lower modularity compared with the resting-state network, which suggest a more efficient global information transmission and between system integrations during task performing. Hub shifts were also observed within the thalamus and the left inferior temporal cortex. The thalamus and the left inferior temporal cortex exhibited higher and lower degrees, respectively in the coactivation network compared with the resting-state network. These results shed light regarding the reconfiguration of the brain networks between task and resting-state conditions, and highlight the role of the thalamus in change of network configurations in task vs. rest. PMID:24062654

Exploring Molecular Speciation and Crystallization Mechanism of Amorphous 2-Phenylamino Nicotinic Acid.

PubMed

Kalra, Arjun; Lubach, Joseph W; Munson, Eric J; Li, Tonglei

2018-02-07

Molecular understanding of phase stability and transition of the amorphous state helps in formulation and manufacturing of poorly-soluble drugs. Crystallization of a model compound, 2-phenylamino nicotinic acid (2PNA), from the amorphous state was studied using solid-state analytical methods. Our previous report suggests that 2PNA molecules mainly develop intermolecular -COOH∙∙∙pyridine N (acid-pyridine) interactions in the amorphous state. In the current study, the molecular speciation is explored with regard to the phase transition from the amorphous to the crystalline state. Using spectroscopic techniques, the molecular interactions and structural evolvement during the recrystallization from the glassy state were investigated. The results unveiled that the structurally heterogeneous amorphous state contains acid-pyridine aggregates - either as hydrogen-bonded neutral molecules or as zwitterions - as well as a population of carboxylic acid dimers. Phase transition from the amorphous state results in crystal structures composed of carboxylic acid dimer (acid-acid) synthon or acid-pyridine chains depending on the crystallization conditions employed. The study underlines the structural evolvement, as well as its impact on the metastability, of amorphous samples from local, supramolecular assemblies to long-range intermolecular ordering through crystallization.

Bayesian network analysis revealed the connectivity difference of the default mode network from the resting-state to task-state

PubMed Central

Wu, Xia; Yu, Xinyu; Yao, Li; Li, Rui

2014-01-01

Functional magnetic resonance imaging (fMRI) studies have converged to reveal the default mode network (DMN), a constellation of regions that display co-activation during resting-state but co-deactivation during attention-demanding tasks in the brain. Here, we employed a Bayesian network (BN) analysis method to construct a directed effective connectivity model of the DMN and compared the organizational architecture and interregional directed connections under both resting-state and task-state. The analysis results indicated that the DMN was consistently organized into two closely interacting subsystems in both resting-state and task-state. The directed connections between DMN regions, however, changed significantly from the resting-state to task-state condition. The results suggest that the DMN intrinsically maintains a relatively stable structure whether at rest or performing tasks but has different information processing mechanisms under varied states. PMID:25309414

A resting-state fMRI study of obese females between pre- and postprandial states before and after bariatric surgery.

PubMed

Wiemerslage, Lyle; Zhou, Wei; Olivo, Gaia; Stark, Julia; Hogenkamp, Pleunie S; Larsson, Elna-Marie; Sundbom, Magnus; Schiöth, Helgi B

2017-02-01

Past studies utilizing resting-state functional MRI (rsfMRI), have shown that obese humans exhibit altered activity in brain areas related to reward compared to normal-weight controls. However, to what extent bariatric surgery-induced weight loss alters resting-state brain activity in obese humans is less well-studied. Thus, we measured the fractional amplitude of low-frequency fluctuations from eyes-closed, rsfMRI in obese females (n = 11, mean age = 42 years, mean BMI = 41 kg/m 2 ) in both a pre- and postprandial state at two time points: four weeks before, and four weeks after bariatric surgery. Several brain areas showed altered resting-state activity following bariatric surgery, including the putamen, insula, cingulate, thalamus and frontal regions. Activity augmented by surgery was also dependent on prandial state. For example, in the fasted state, activity in the middle frontal and pre- and postcentral gyri was found to be decreased after surgery. In the sated state, activity within the insula was increased before, but not after surgery. Collectively, our results suggest that resting-state neural functions are rapidly affected following bariatric surgery and the associated weight loss and change in diet. © 2016 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Longitudinal assessment of neuropsychological function in major depression.

PubMed

Douglas, Katie M; Porter, Richard J

2009-12-01

Neuropsychological impairment is a core component of major depression, yet its relationship to clinical state is unclear. The aims of the present review were to determine which neuropsychological domains and tasks were most sensitive to improvement in clinical state in major depression and to highlight the methodological issues in such research. Studies that included a baseline and at least one follow-up neuropsychological testing session in adults with major depression were identified using MEDLINE, Web of Science and ScienceDirect databases. Thirty studies were included in the review. Findings in younger adult populations suggested that improvement in mood was most strongly related to improved verbal memory and verbal fluency, while measures of executive functioning and attention tended to remain impaired across treatment. In late-life major depression, improved psychomotor speed was most closely related to treatment response, but there was much inconsistency between study findings, which may be due to methodological issues. In major depression, particular neuropsychological domains are more strongly related to clinical state than others. The findings from the present review suggest that the domains most sensitive to clinical state are verbal learning and memory, verbal fluency and psychomotor speed. In contrast, measures of attention and executive functioning perhaps represent more trait-like markers of major depression. With further methodologically sound research, the changes in neuropsychological function associated with treatment response may provide a means of evaluating different treatment strategies in major depression.

Impacts of Co-doping on the superconductivity and the orbital ordering state in Fe1-xCoxSe single crystal studied by the electrical transport.

NASA Astrophysics Data System (ADS)

Urata, Takahiro; Tanabe, Yoichi; Heguri, Satoshi; Tanigaki, Katsumi

2015-03-01

In the FeSe with the simplest crystal structure in the Fe-based superconductor families, although both the superconductivity and the orbital ordering states are investigated, the relation between them is still unclear. Here, we report Co doping effects on the superconductivity and the orbital ordering state in Fe1-xCoxSe single crystals. The electrical transport measurements demonstrated that the superconductivity vanishes at 4 % Co doping while the orbital ordering state may be robust against Co doping. Present results suggest that the orbital ordering state is not related to the emergence of the superconductivity in FeSe.

The Supply of Physicians Waivered to Prescribe Buprenorphine for Opioid Use Disorders in the United States: A State-Level Analysis.

PubMed

Knudsen, Hannah K

2015-07-01

The U.S. Food and Drug Administration's approval of buprenorphine in 2002 expanded options for treating opioid use disorder (OUD). Physicians who intend to treat OUD patients with buprenorphine must seek a waiver to prescribe it, which may contribute to state-by-state variation in the supply of waivered physicians. This study integrates data extracted from the U.S. Drug Enforcement Agency's database of waivered physicians with state-level indicators of the macro environment, health-related resources, and treatment demand. In December 2013, the average state had 8.0 waivered physicians per 100,000 residents (SD = 5.2). Large regional differences between states in the Northeast relative to states in the Midwest, South, and West were observed. The percentage of residents covered by Medicaid as well as the population-adjusted availability of opioid treatment programs and substance use disorder treatment facilities were positively associated with buprenorphine physician supply. Buprenorphine physician supply was positively correlated with states' rates of overdose deaths, suggesting that physicians may seek the waiver in response to the magnitude of the opioid problem in their state. States with greater health-related resources, particularly in terms of the supply of opioid treatment programs and substance use disorder treatment programs, had more waivered physicians in 2013. The finding regarding Medicaid coverage suggests that states implementing Medicaid expansion under health reform may experience additional growth in buprenorphine physician supply. However, large regional disparities in the supply of waivered physicians may impede access to care for many Americans with OUD.

Growth Phase, Oxygen, Temperature, and Starvation Affect the Development of Viable but Non-culturable State of Vibrio cholerae.

PubMed

Wu, Bin; Liang, Weili; Kan, Biao

2016-01-01

Vibrio cholerae can enter into a viable but non-culturable (VBNC) state in order to survive in unfavorable environments. In this study, we studied the roles of five physicochemical and microbiological factors or states, namely, different strains, growth phases, oxygen, temperature, and starvation, on the development of VBNC of V. cholerae in artificial sea water (ASW). Different strains of the organism, the growth phase, and oxygen levels affected the progress of VBNC development. It was found that the VBNC state was induced faster in V. cholerae serogroup O1 classical biotype strain O395 than in O1 El Tor biotype strains C6706 and N16961. When cells in different growth phases were used for VBNC induction, stationary-phase cells lost their culturability more quickly than exponential-phase cells, while induction of a totally non-culturable state took longer to achieve for stationary-phase cells in all three strains, suggesting that heterogeneity of cells should be considered. Aeration strongly accelerated the loss of culturability. During the development of the VBNC state, the culturable cell count under aeration conditions was almost 10(6)-fold lower than under oxygen-limited conditions for all three strains. The other two factors, temperature and nutrients-rich environment, may prevent the induction of VBNC cells. At 22 or 37°C in ASW, most of the cells rapidly died and the culturable cell count reduced from about 10(8) to 10(6)-10(5) CFU/mL. The total cell counts showed that cells that lost viability were decomposed, and the viable cell counts were the same as culturable cell counts, indicating that the cells did not reach the VBNC state. VBNC state development was blocked when ASW was supplied with Luria-Bertani broth (LB), but it was not affected in ASW with M9, suggesting that specific nutrients in LB may prevent the development of VBNC state. These results revealed that the five factors evaluated in this study had different roles during the progress of VBNC induction. Changing a single factor could influence and even block the development of the VBNC state. These findings provide new insight to help design further studies to better understand the mechanisms which trigger the development and regulation of the VBNC state.

Maternal Talk in Cognitive Development: Relations between Psychological Lexicon, Semantic Development, Empathy, and Temperament

PubMed Central

Rollo, Dolores; Sulla, Francesco

2016-01-01

In this study, we investigated the relationship between mothers' psychological lexicon and children's cognitive and socio-emotive development as assessed through conceptual and semantic understanding tasks, in addition to the traditional tasks of theory of mind. Currently, there is considerable evidence to suggest that the frequency of mothers' mental state words used in mother-child picture-book reading is linked with children's theory of mind skills. Furthermore, mothers' use of cognitive terms is more strongly related to children's theory of mind performances than the mothers' references to other mental states, such as desires or emotions (Rollo and Buttiglieri, 2009). Current literature has established that early maternal input is related to later child mental state understanding; however it has not yet clarified which maternal terms are most useful for the socio-emotional and cognitive development of the child, and which aspect of the cognitive development benefits from the mother-child interaction. The present study addresses this issue and focuses on the relationship between mothers' mental state talk and children's behavior in conceptual and semantic tasks, and in a theory of mind task. In this study fifty pairs consisting of mothers and their 3 to 6-year-old children participated in two sessions: (1) The mothers read a picture book to their children. To assess the maternal psychological lexicon, their narrative was codified according to the categories of mental state references used in literature: perceptual, emotional, volitional, cognitive, moral, and communicative. (2) After a few days, the conceptual and semantic skills of the children (tasks of contextualization and classification, memory, and definition of words) and their psychological lexicon were assessed. The results suggest close links between the frequency and variety of mothers' mental state words and some semantic and conceptual skills of children. PMID:27047421

Maternal Talk in Cognitive Development: Relations between Psychological Lexicon, Semantic Development, Empathy, and Temperament.

PubMed

Rollo, Dolores; Sulla, Francesco

2016-01-01

In this study, we investigated the relationship between mothers' psychological lexicon and children's cognitive and socio-emotive development as assessed through conceptual and semantic understanding tasks, in addition to the traditional tasks of theory of mind. Currently, there is considerable evidence to suggest that the frequency of mothers' mental state words used in mother-child picture-book reading is linked with children's theory of mind skills. Furthermore, mothers' use of cognitive terms is more strongly related to children's theory of mind performances than the mothers' references to other mental states, such as desires or emotions (Rollo and Buttiglieri, 2009). Current literature has established that early maternal input is related to later child mental state understanding; however it has not yet clarified which maternal terms are most useful for the socio-emotional and cognitive development of the child, and which aspect of the cognitive development benefits from the mother-child interaction. The present study addresses this issue and focuses on the relationship between mothers' mental state talk and children's behavior in conceptual and semantic tasks, and in a theory of mind task. In this study fifty pairs consisting of mothers and their 3 to 6-year-old children participated in two sessions: (1) The mothers read a picture book to their children. To assess the maternal psychological lexicon, their narrative was codified according to the categories of mental state references used in literature: perceptual, emotional, volitional, cognitive, moral, and communicative. (2) After a few days, the conceptual and semantic skills of the children (tasks of contextualization and classification, memory, and definition of words) and their psychological lexicon were assessed. The results suggest close links between the frequency and variety of mothers' mental state words and some semantic and conceptual skills of children.

The molten globule state is unusually deformable under mechanical force

PubMed Central

Elms, Phillip J.; Chodera, John D.; Bustamante, Carlos; Marqusee, Susan

2012-01-01

Recently, the role of force in cellular processes has become more evident, and now with advances in force spectroscopy, the response of proteins to force can be directly studied. Such studies have found that native proteins are brittle, and thus not very deformable. Here, we examine the mechanical properties of a class of intermediates referred to as the molten globule state. Using optical trap force spectroscopy, we investigated the response to force of the native and molten globule states of apomyoglobin along different pulling axes. Unlike natively folded proteins, the molten globule state of apomyoglobin is compliant (large distance to the transition state); this large compliance means that the molten globule is more deformable and the unfolding rate is more sensitive to force (the application of force or tension will have a more dramatic effect on the unfolding rate). Our studies suggest that these are general properties of molten globules and could have important implications for mechanical processes in the cell. PMID:22355138

Vibrational wave packet dynamics in NaK: The A 1Σ+ state

NASA Astrophysics Data System (ADS)

Andersson, L. Mauritz; Karlsson, Hans O.; Goscinski, Osvaldo; Berg, Lars-Erik; Beutter, Matthias; Hansson, Tony

1999-02-01

A combined experimental and theoretical study of the vibrational wave packet dynamics for the NaK molecule in the A 1Σ+ state is presented. The experiment utilises a 790 nm one-colour femtosecond pump-probe scheme with detection of a previously not reported dissociation pathway of the 3 1Π+ state, leading to the Na(3p)+K(4s) product channel. The dissociation is suggested to proceed via either collisionally mediated processes or a molecular cascading process via the 4 1Σ+ state, which crosses several states correlating to the Na(3p)+K(4s) limit. Time-dependent quantum mechanical calculations are used for studying the dynamics in detail. Simulations are performed both for 790 nm and for 766 nm, to relate also to earlier studies. The previous interpretations of the probe processes are revised. Inclusion of vibrational and rotational temperature effects are shown to be crucial for explaining the shape of the signal and the vibrational period, and leads to excellent agreement with the experiments.

Ecologically unequal exchange, recessions, and climate change: A longitudinal study.

PubMed

Huang, Xiaorui

2018-07-01

This study investigates how the ecologically unequal exchange of carbon dioxide emissions varies with economic recessions. I propose a country-specific approach to examine (1) the relationship between carbon dioxide emissions in developing countries and the "vertical flow" of exports to the United States; and (2) the variations of the relationship before, during, and after two recent economic recessions in 2001 and 2008. Using data on 69 developing nations between 2000 and 2010, I estimate time-series cross-sectional regression models with two-way fixed effects. Results suggest that the vertical flow of exports to the United States is positively associated with carbon dioxide emissions in developing countries. The magnitude of this relationship increased in 2001, 2009, and 2010, and decreased in 2008, but remained stable in non-recession periods, suggesting that economic recessions in the United States are associated with variations of ecologically unequal exchange. Results highlight the impacts of U.S. recessions on carbon emissions in developing countries through the structure of international trade. Copyright © 2018 Elsevier Inc. All rights reserved.

Trauma and Aggression: Investigating the Mediating Role of Mentalizing in Female and Male Inpatient Adolescents.

PubMed

Abate, Anna; Marshall, Kaisa; Sharp, Carla; Venta, Amanda

2017-12-01

High rates of posttraumatic stress disorder (PTSD) symptoms and elevated levels of aggression are common among youth in inpatient psychiatric settings. Several models link trauma exposure to aggression through anomalous mental state reasoning. Some theoretical frameworks linking trauma to aggression specify that the over-attribution of hostile mental states contributes to the development of aggressive behavior whereas other theories suggest that an inhibition of mental state reasoning leads to aggressive behavior. Using a sample of inpatient adolescents, the current study examined relations between PTSD symptoms and four forms of aggression, exploring the role of both over- and under-mentalizing (i.e., hypo- and hypermentalizing) as mediators and gender as a moderator. The results suggest that hypermentalizing, but not hypomentalizing, mediates the relation between trauma and aggression, extending prior research related to inpatient adolescents for the first time. Evidence of moderated mediation was noted, such that this mediational relation was evident for females but not males. The current study offers support for differential underlying causes of aggression among males and females with PTSD symptoms.

Does higher income inequality adversely influence infant mortality rates? Reconciling descriptive patterns and recent research findings.

PubMed

Siddiqi, Arjumand; Jones, Marcella K; Erwin, Paul Campbell

2015-04-01

As the struggle continues to explain the relatively high rates of infant mortality (IMR) exhibited in the United States, a renewed emphasis is being placed on the role of possible 'contextual' determinants. Cross-sectional and short time-series studies have found that higher income inequality is associated with higher IMR at the state level. Yet, descriptively, the longer-term trends in income inequality and in IMR seem to call such results into question. To assess whether, over the period 1990-2007, state-level income inequality is associated with state-level IMR; to examine whether the overall effect of income inequality on IMR over this period varies by state; to test whether the association between income inequality and IMR varies across this time period. IMR data--number of deaths per 1000 live births in a given state and year--were obtained from the U.S. Centers for Disease Control Wonder database. Income inequality was measured using the Gini coefficient, which varies from zero (complete equality) to 100 (complete inequality). Covariates included state-level poverty rate, median income, and proportion of high school graduates. Fixed and random effects regressions were conducted to test hypotheses. Fixed effects models suggested that, overall, during the period 1990-2007, income inequality was inversely associated with IMR (β = -0.07, SE (0.01)). Random effects models suggested that when the relationship was allowed to vary at the state-level, it remained inverse (β = -0.05, SE (0.01)). However, an interaction between income inequality and time suggested that, as time increased, the effect of income inequality had an increasingly positive association with total IMR (β = 0.009, SE (0.002)). The influence of state income inequality on IMR is dependent on time, which may proxy for time-dependent aspects of societal context. Copyright © 2015 Elsevier Ltd. All rights reserved.

Solid-State Lighting 2017 Suggested Research Topics Supplement: Technology and Market Context

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

A 2017 update to the Solid-State Lighting R&D Plan that is divided into two documents. The first document describes a list of suggested SSL priority research topics and the second document provides context and background, including information drawn from technical, market, and economic studies. Widely referenced by industry and government both here and abroad, these documents reflect SSL stakeholder inputs on key R&D topics that will improve efficacy, reduce cost, remove barriers to adoption, and add value for LED and OLED lighting solutions over the next three to five years, and discuss those applications that drive and prioritize the specificmore » R&D.« less

Acquisition of mental state language in Mandarin- and Cantonese-speaking children.

PubMed

Tardif, T; Wellman, H M

2000-01-01

Children's theory of mind appears to develop from a focus on desire to a focus on belief. However, it is not clear (a) whether this pattern is universal and (b) whether it could also be explained by linguistic and sociocultural factors. This study examined mental state language in 10 Mandarin-speaking (21-27 months) and 8 Cantonese-speaking (18-44 months) toddlers. The results suggest a pattern of theory-of-mind development similar to that in English, with early use of desire terms followed by other mental state references. However, the Chinese-speaking children used desire terms much earlier, and the use of terms for thinking was very infrequent, even for Mandarin-speaking adults. This finding suggests a consistency in the overall sequence, but variation in the timing of beginning and end points, in children's theory-of-mind development across cultures.

Support for Restorative Justice in a Sample of U.S. University Students.

PubMed

Ahlin, Eileen M; Gibbs, Jennifer C; Kavanaugh, Philip R; Lee, Joongyeup

2017-02-01

Theories of restorative justice suggest that the practice works best when offenders are enmeshed in multiple interdependencies or attachments to others and belong to a culture that facilitates communitarianism instead of individualism. Restorative justice principles and practices are thus believed to be incongruent with the individualistic culture and legal system of the United States, especially compared with that of nations like Australia and Japan. Using a nonprobability convenience sample of students enrolled in a large public university in the United States, our study examines attitudes toward restorative justice as a fair and just process for reintegrating offenders and meeting the needs of victims. Results indicate that our sample holds less punitive attitudes than citizens in either Australia or Japan. Our findings are discussed in light of recent policy shifts in the United States that suggest a concerted move toward decarceration following the 2008 recession.

Plasmodium knowlesi from archival blood films: Further evidence that human infections are widely distributed and not newly emergent in Malaysian Borneo

PubMed Central

Lee, Kim-Sung; Cox-Singh, Janet; Brooke, George; Matusop, Asmad; Singh, Balbir

2009-01-01

Human infections with Plasmodium knowlesi have been misdiagnosed by microscopy as Plasmodium malariae due to their morphological similarities. Although microscopy-identified P. malariae cases have been reported in the state of Sarawak (Malaysian Borno) as early as 1952, recent epidemiological studies suggest the absence of indigenous P. malariae infections. The present study aimed to determine the past incidence and distribution of P. knowlesi infections in the state of Sarawak based on archival blood films from patients diagnosed by microscopy as having P. malariae infections. Nested PCR assays were used to identify Plasmodium species in DNA extracted from 47 thick blood films collected in 1996 from patients in seven different divisions throughout the state of Sarawak. Plasmodium knowlesi DNA was detected in 35 (97.2%) of 36 blood films that were positive for Plasmodium DNA, with patients originating from all seven divisions. Only one sample was positive for P. malariae DNA. This study provides further evidence of the widespread distribution of human infections with P. knowlesi in Sarawak and its past occurrence. Taken together with data from previous studies, our findings suggest that P. knowlesi malaria is not a newly emergent disease in humans. PMID:19358848

Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder

PubMed Central

Sripada, Rebecca K.; King, Anthony P.; Garfinkel, Sarah N.; Wang, Xin; Sripada, Chandra S.; Welsh, Robert C.; Liberzon, Israel

2012-01-01

Background Converging neuroimaging research suggests altered emotion neurocircuitry in individuals with posttraumatic stress disorder (PTSD). Emotion activation studies in these individuals have shown hyperactivation in emotion-related regions, including the amygdala and insula, and hypoactivation in emotion-regulation regions, including the medial prefrontal cortex (mPFC) and anterior cingulate cortex (ACC). However, few studies have examined patterns of connectivity at rest in individuals with PTSD, a potentially powerful method for illuminating brain network structure. Methods Using the amygdala as a seed region, we measured resting-state brain connectivity using 3 T functional magnetic resonance imaging in returning male veterans with PTSD and combat controls without PTSD. Results Fifteen veterans with PTSD and 14 combat controls enrolled in our study. Compared with controls, veterans with PTSD showed greater positive connectivity between the amygdala and insula, reduced positive connectivity between the amygdala and hippocampus, and reduced anticorrelation between the amygdala and dorsal ACC and rostral ACC. Limitations Only male veterans with combat exposure were tested, thus our findings cannot be generalized to women or to individuals with non–combat related PTSD. Conclusion These results demonstrate that studies of functional connectivity during resting state can discern aberrant patterns of coupling within emotion circuits and suggest a possible brain basis for emotion-processing and emotion-regulation deficits in individuals with PTSD. PMID:22313617

The morphological state space revisited: what do phylogenetic patterns in homoplasy tell us about the number of possible character states?

PubMed Central

Hoyal Cuthill, Jennifer F.

2015-01-01

Biological variety and major evolutionary transitions suggest that the space of possible morphologies may have varied among lineages and through time. However, most models of phylogenetic character evolution assume that the potential state space is finite. Here, I explore what the morphological state space might be like, by analysing trends in homoplasy (repeated derivation of the same character state). Analyses of ten published character matrices are compared against computer simulations with different state space models: infinite states, finite states, ordered states and an ‘inertial' model, simulating phylogenetic constraints. Of these, only the infinite states model results in evolution without homoplasy, a prediction which is not generally met by real phylogenies. Many authors have interpreted the ubiquity of homoplasy as evidence that the number of evolutionary alternatives is finite. However, homoplasy is also predicted by phylogenetic constraints on the morphological distance that can be traversed between ancestor and descendent. Phylogenetic rarefaction (sub-sampling) shows that finite and inertial state spaces do produce contrasting trends in the distribution of homoplasy. Two clades show trends characteristic of phylogenetic inertia, with decreasing homoplasy (increasing consistency index) as we sub-sample more distantly related taxa. One clade shows increasing homoplasy, suggesting exhaustion of finite states. Different clades may, therefore, show different patterns of character evolution. However, when parsimony uninformative characters are excluded (which may occur without documentation in cladistic studies), it may no longer be possible to distinguish inertial and finite state spaces. Interestingly, inertial models predict that homoplasy should be clustered among comparatively close relatives (parallel evolution), whereas finite state models do not. If morphological evolution is often inertial in nature, then homoplasy (false homology) may primarily occur between close relatives, perhaps being replaced by functional analogy at higher taxonomic scales. PMID:26640650

SEASONAL NH 3 EMISSIONS FOR THE CONTINENTAL UNITED STATES: INVERSE MODEL ESTIMATION AND EVALUATION

EPA Science Inventory

An inverse modeling study has been conducted here to evaluate a prior estimate of seasonal ammonia (NH₃) emissions. The prior estimates were based on a previous inverse modeling study and two other bottom-up inventory studies. The results suggest that the prior estim...

A Longitudinal Study of School Districts' Sustained Improvement

ERIC Educational Resources Information Center

Sampson, Pauline M.

2011-01-01

In this longitudinal study of one region in the state of Texas, there was an examination of district leadership and the sustaining of high student achievement for their districts. The results of this study suggest that sustained improvement of student achievement is very difficult. The districts that had sustained improvement had stable district…

Measuring the Influences That Affect Technological Literacy in Rhode Island High Schools

ERIC Educational Resources Information Center

Walach, Michael

2015-01-01

This study sampled the current state of technological literacy in Rhode Island high schools using a new instrument, the Technological Literacy Assessment, which was developed for this study. Gender inequalities in technological literacy were discovered, and possible causes and solutions are presented. This study suggests possible next steps for…

The Development and Validation of the Mood-based Indoor Tanning Scale.

PubMed

Carcioppolo, Nick; Chen, Yixin; John, Kevin K; Gonzalez, Andrea Martinez; King, Andy J; Morgan, Susan E; Hu, Shasa

2017-01-01

Research indicates that mood-based motivations may be an important predictor of indoor tanning bed use and may be related to indoor tanning dependence. Problematically, little research has been conducted to develop a psychometric measure of mood-based tanning motivations. The current study seeks to develop and validate the moodbased indoor tanning scale (MITS). Two studies were conducted to identify and verify the MITS factor structure as well as assess construct validity. Study 1 was conducted at 5 geographically diverse universities in the United States. Study 2 was conducted by using a national online sample in the United States. Results from study 1 specified the factor structure of the MITS. Results from study 2 suggest that a one-point increase in the MITS measure corresponds with using indoor tanning beds 11 more times in the past year. These findings demonstrate that moodbased tanning motivations are a strong predictor of indoor tanning intentions and behavior. Further, they suggest that health behavior researchers and healthcare practitioners can use the MITS to assess the extent to which mood-based motivations impact indoor tanning bed use.

Defects in a nonlinear pseudo one-dimensional solid

NASA Astrophysics Data System (ADS)

Blanchet, Graciela B.; Fincher, C. R., Jr.

1985-03-01

These infrared studies of acetanilide together with the existence of two equivalent structures for the hydrogen-bonded chain suggest the possibility of a topological defect state rather than a Davydov soliton as suggested previously. Acetanilide is an example of a class of one-dimensional materials where solitons are a consequence of a twofold degenerate structure and the nonlinear dynamics of the hydrogen-bonded network.

Concentrated evolutionary novelties in the foot musculature of Odontophrynidae (Anura: Neobatrachia), with comments on adaptations for burrowing.

PubMed

Blotto, Boris L; Pereyra, Martin O; Faivovich, Julián; Dias, Pedro Henrique Dos Santos; Grant, Taran

2017-05-02

We studied the foot musculature of the fossorial family Odontophrynidae (composed of the genera Macrogenioglottus, Odontophrynus, and Proceratophrys) plus several outgroup taxa from Hyloidea and other burrowing taxa from across Anura. We found novel character-states supporting the monophyly of Odontophrynus, Proceratophrys, and Odontophrynus + Macrogenioglottus. The character-states observed in O. cultripes support conflicting phylogenetic positions within Odontophrynus. A comparison of some novel character-states with a diverse sample of burrowing taxa suggests that some modifications of the foot musculature might be involved in digging.

The effects of modeling contingencies in the treatment of food selectivity in children with autism.

PubMed

Fu, Sherrene B; Penrod, Becky; Fernand, Jonathan K; Whelan, Colleen M; Griffith, Kristin; Medved, Shannon

2015-11-01

The current study investigated the effectiveness of stating and modeling contingencies in increasing food consumption for two children with food selectivity. Results suggested that stating and modeling a differential reinforcement (DR) contingency for food consumption was effective in increasing consumption of two target foods for one child, and stating and modeling a DR plus nonremoval of the spoon contingency was effective in increasing consumption of the remaining food for the first child and all target foods for the second child. © The Author(s) 2015.

An Analytic Study of the Uneconomic Lower Primary Schools in Malappuram District

ERIC Educational Resources Information Center

Vijayakumari, K.; Kayikkara, Vaheeda

2010-01-01

Background: A few studies have been conducted on area of uneconomic schools. And most of these studies are related with fertility decline in the state. Purpose: The study intended to find out physical conditions of uneconomic lower primary schools, to identify the factors causing the schools uneconomic and to provide suggestions for improving the…

Mitochondrial DNA diversity of honey bees (Apis mellifera) from unmanaged colonies and swarms in the United States.

PubMed

Magnus, Roxane M; Tripodi, Amber D; Szalanski, Allen L

2014-06-01

To study the genetic diversity of honey bees (Apis mellifera L.) from unmanaged colonies in the United States, we sequenced a portion of the mitochondrial DNA COI-COII region. From the 530 to 1,230 bp amplicon, we observed 23 haplotypes from 247 samples collected from 12 states, representing three of the four A. mellifera lineages known to have been imported into the United States (C, M, and O). Six of the 13 C lineage haplotypes were not found in previous queen breeder studies in the United States. The O lineage accounted for 9% of unmanaged colonies which have not yet been reported in queen breeder studies. The M lineage accounted for a larger portion of unmanaged samples (7%) than queen breeder samples (3%). Based on our mitochondrial DNA data, the genetic diversity of unmanaged honey bees in the United States differs significantly from that of queen breeder populations (p < 0.00001). The detection of genetically distinct maternal lineages of unmanaged honey bees suggests that these haplotypes may have existed outside the managed honey bee population for a long period.

Negotiating reform at an arm's length from the state: Disease Management Programmes and the introduction of clinical standards in Germany.

PubMed

Burau, Viola

2009-07-01

Studies of German health policy often highlight institutional constraints to reform. However, based on a case study of the introduction of clinical standards as part of the Disease Management Programmes for chronic illnesses, this article suggests that negotiating reform at an arm's length from the state can also lead to governance change, although the strengthening of hierarchy is not as prominent as that in some of the countries studied in this special issue. As such, the case of Germany offers interesting insights into the politics of governance change that occur in the shadow, but largely without the direct involvement of the state, which is typical of a corporatist health-care state. In this respect, the analysis identifies three leverages for change. First, the change in medical governance explicitly builds on earlier reforms and gives the reform alliance a competitive edge. Second, the organisations of the joint self-administration, as a more or less open ally of the state, play an influential role throughout the reform process. Importantly and third, this is complemented by the state steering at a distance.

Steady-state and transient operation of a heat-pipe radiator system

NASA Technical Reports Server (NTRS)

Sellers, J. P.

1974-01-01

Data obtained on a VCHP heat-pipe radiator system tested in a vacuum environment were studied. Analyses and interpretation of the steady-state results are presented along with an initial analysis of some of the transient data. Particular emphasis was placed on quantitative comparisons of the experimental data with computer model simulations. The results of the study provide a better understanding of the system but do not provide a complete explanation for the observed low VCHP performance and the relatively flat radiator panel temperature distribution. The results of the study also suggest hardware, software, and testing improvements.

Impacts of telemation on modern society

NASA Technical Reports Server (NTRS)

Alexander, A. D., III

1973-01-01

A 90-day study was made of teleoperators, robotics, and remote systems technology in the United States. The purpose of the study was to survey state-of-the-art technology in this field, determine major user needs in medicine, mining, and oceanography, and suggest initiatives where federal research and development funding would most significantly impact the application of this technology to the alleviation of explicit national social problems. Following a review of the findings of this study commencing with user needs, speculation is made on impending developments in the application of telemation to remote emergency medical care and remote mining systems.

The relationship between addictions and bariatric surgery for nurses in recovery.

PubMed

Fogger, Susanne A; McGuinness, Teena M

2012-01-01

Determinants of morbid obesity are complex and numerous, yet understanding the neurobiological underpinnings improves our knowledge of this serious issue. Emerging science supports a comparison of disordered eating with other addictive substances. The study used a sub-analysis of a cross-sectional study of nurses in a state-monitoring program. A study of 173 participants in a state-monitoring program for impaired nurses revealed that 14% (n= 25) had undergone bariatric surgery. Of these, 17 developed an addiction after surgery. Evidence suggests that some individuals may require additional treatment, similar to those with pharmacological addictions. © 2011 Wiley Periodicals, Inc.

A Proteomic Signature of Dormancy in the Actinobacterium Micrococcus luteus.

PubMed

Mali, Sujina; Mitchell, Morgan; Havis, Spencer; Bodunrin, Abiodun; Rangel, Jonathan; Olson, Gabriella; Widger, William R; Bark, Steven J

2017-07-15

Dormancy is a protective state in which diverse bacteria, including Mycobacterium tuberculosis , Staphylococcus aureus , Treponema pallidum (syphilis), and Borrelia burgdorferi (Lyme disease), curtail metabolic activity to survive external stresses, including antibiotics. Evidence suggests dormancy consists of a continuum of interrelated states, including viable but nonculturable (VBNC) and persistence states. VBNC and persistence contribute to antibiotic tolerance, reemergence from latent infections, and even quorum sensing and biofilm formation. Previous studies indicate that the protein mechanisms regulating persistence and VBNC states are not well understood. We have queried the VBNC state of Micrococcus luteus NCTC 2665 (MI-2665) by quantitative proteomics combining gel electrophoresis, high-performance liquid chromatography, and tandem mass spectrometry to elucidate some of these mechanisms. MI-2665 is a nonpathogenic actinobacterium containing a small (2.5-Mb), high-GC-content genome which exhibits a well-defined VBNC state induced by nutrient deprivation. The MI-2665 VBNC state demonstrated a loss of protein diversity accompanied by increased levels of 18 proteins that are conserved across actinobacteria, 14 of which have not been previously identified in VNBC. These proteins implicate an anaplerotic strategy in the transition to VBNC, including changes in the glyoxylate shunt, redox and amino acid metabolism, and ribosomal regulatory processes. Our data suggest that MI-2665 is a viable model for dissecting the protein mechanisms underlying the VBNC stress response and provide the first protein-level signature of this state. We expect that this protein signature will enable future studies deciphering the protein mechanisms of dormancy and identify novel therapeutic strategies effective against antibiotic-tolerant bacterial infections. IMPORTANCE Dormancy is a protective state enabling bacteria to survive antibiotics, starvation, and the immune system. Dormancy is comprised of different states, including persistent and viable but nonculturable (VBNC) states that contribute to the spread of bacterial infections. Therefore, it is imperative to identify how bacteria utilize these different dormancy states to survive antibiotic treatment. The objective of our research is to eliminate dormancy as a route to antibiotic tolerance by understanding the proteins that control dormancy in Micrococcus luteus NCTC 2665. This bacterium has unique advantages for studying dormancy, including a small genome and a well-defined and reproducible VBNC state. Our experiments implicate four previously identified and 14 novel proteins upregulated in VBNC that may regulate this critical survival mechanism. Copyright © 2017 American Society for Microbiology.

Caregiver stress: does states' expenditure on home- and community-based services matter?

PubMed

Hong, Michin; Casado, Banghwa Lee

2015-01-01

This study examined how state expenditure on home- and community-based services (HCBS) and individual factors are associated with caregiver stress. A total of 1,849 cases from the 2004 National Long-Term Care Survey were included. Gender, education, perceived physical strain, and economic hardship, as well as the number of limitations in instrumental activities of daily living (IADL) for the care recipient, were associated with caregiver stress. The cross-level interaction between service utilization and state expenditure on HCBS was significant, suggesting that living in states with a higher expenditure on HCBS is associated with reduced stress regardless of service utilization.

Colorectal Cancer Screening Practices Among Men and Women in Rural and Nonrural Areas of the United States, 1999

ERIC Educational Resources Information Center

Coughlin, Steven S.; Thompson, Trevor D.

2004-01-01

Previous studies have suggested that men and women in rural areas are less likely than those in urban areas to receive routine cancer screening. Methods: We examined the colorectal cancer screening practices of men (n = 23,565) and women (n = 37,847) aged >50 years living in rural areas and other areas of the United States using data from the…

Biodiversity loss and turnover in alternative states in the Mediterranean Sea: a case study on meiofauna

PubMed Central

Bianchelli, Silvia; Buschi, Emanuela; Danovaro, Roberto; Pusceddu, Antonio

2016-01-01

In the Mediterranean Sea hard-bottom macroalgal meadows may switch to alternative and less-productive barrens grounds, as a result of sea urchins overgrazing. Meiofauna (and especially nematodes) represent key components of benthic ecosystems, are highly-diversified, sensitive to environmental change and anthropogenic impacts, but, so-far, have been neglected in studies on regime shifts. We report here that sedimentary organic matter contents, meiofaunal taxa richness and community composition, nematode α- and β-biodiversity vary significantly between alternative macroalgal and barren states. The observed differences are consistent in six areas spread across the Mediterranean Sea, irrespective of barren extent. Our results suggest also that the low biodiversity levels in barren states are the result of habitat loss/fragmentation, which is associated also with a lower availability of trophic resources. Furthermore, differences in meiofaunal and nematode abundance, biomass and diversity between macroalgal meadow and barren states persist when the latter is not fully formed, or consists of patches interspersed in macroalgal meadows. Since barren grounds are expanding rapidly along the Mediterranean Sea and meiofauna are a key trophic component in marine ecosystems, we suggest that the extension and persistence of barrens at the expenses of macroalgal meadows could also affect resilience of higher trophic level. PMID:27708343

Biodiversity loss and turnover in alternative states in the Mediterranean Sea: a case study on meiofauna.

PubMed

Bianchelli, Silvia; Buschi, Emanuela; Danovaro, Roberto; Pusceddu, Antonio

2016-10-06

In the Mediterranean Sea hard-bottom macroalgal meadows may switch to alternative and less-productive barrens grounds, as a result of sea urchins overgrazing. Meiofauna (and especially nematodes) represent key components of benthic ecosystems, are highly-diversified, sensitive to environmental change and anthropogenic impacts, but, so-far, have been neglected in studies on regime shifts. We report here that sedimentary organic matter contents, meiofaunal taxa richness and community composition, nematode α- and β-biodiversity vary significantly between alternative macroalgal and barren states. The observed differences are consistent in six areas spread across the Mediterranean Sea, irrespective of barren extent. Our results suggest also that the low biodiversity levels in barren states are the result of habitat loss/fragmentation, which is associated also with a lower availability of trophic resources. Furthermore, differences in meiofaunal and nematode abundance, biomass and diversity between macroalgal meadow and barren states persist when the latter is not fully formed, or consists of patches interspersed in macroalgal meadows. Since barren grounds are expanding rapidly along the Mediterranean Sea and meiofauna are a key trophic component in marine ecosystems, we suggest that the extension and persistence of barrens at the expenses of macroalgal meadows could also affect resilience of higher trophic level.

Biodiversity loss and turnover in alternative states in the Mediterranean Sea: a case study on meiofauna

NASA Astrophysics Data System (ADS)

Bianchelli, Silvia; Buschi, Emanuela; Danovaro, Roberto; Pusceddu, Antonio

2016-10-01

In the Mediterranean Sea hard-bottom macroalgal meadows may switch to alternative and less-productive barrens grounds, as a result of sea urchins overgrazing. Meiofauna (and especially nematodes) represent key components of benthic ecosystems, are highly-diversified, sensitive to environmental change and anthropogenic impacts, but, so-far, have been neglected in studies on regime shifts. We report here that sedimentary organic matter contents, meiofaunal taxa richness and community composition, nematode α- and β-biodiversity vary significantly between alternative macroalgal and barren states. The observed differences are consistent in six areas spread across the Mediterranean Sea, irrespective of barren extent. Our results suggest also that the low biodiversity levels in barren states are the result of habitat loss/fragmentation, which is associated also with a lower availability of trophic resources. Furthermore, differences in meiofaunal and nematode abundance, biomass and diversity between macroalgal meadow and barren states persist when the latter is not fully formed, or consists of patches interspersed in macroalgal meadows. Since barren grounds are expanding rapidly along the Mediterranean Sea and meiofauna are a key trophic component in marine ecosystems, we suggest that the extension and persistence of barrens at the expenses of macroalgal meadows could also affect resilience of higher trophic level.

Meditation-induced neuroplastic changes in amygdala activity during negative affective processing.

PubMed

Leung, Mei-Kei; Lau, Way K W; Chan, Chetwyn C H; Wong, Samuel S Y; Fung, Annis L C; Lee, Tatia M C

2018-06-01

Recent evidence suggests that the effects of meditation practice on affective processing and resilience have the potential to induce neuroplastic changes within the amygdala. Notably, literature speculates that meditation training may reduce amygdala activity during negative affective processing. Nonetheless, studies have thus far not verified this speculation. In this longitudinal study, participants (N = 21, 9 men) were trained in awareness-based compassion meditation (ABCM) or matched relaxation training. The effects of meditation training on amygdala activity were examined during passive viewing of affective and neutral stimuli in a non-meditative state. We found that the ABCM group exhibited significantly reduced anxiety and right amygdala activity during negative emotion processing than the relaxation group. Furthermore, ABCM participants who performed more compassion practice had stronger right amygdala activity reduction during negative emotion processing. The lower right amygdala activity after ABCM training may be associated with a general reduction in reactivity and distress. As all participants performed the emotion processing task in a non-meditative state, it appears likely that the changes in right amygdala activity are carried over from the meditation practice into the non-meditative state. These findings suggest that the distress-reducing effects of meditation practice on affective processing may transfer to ordinary states, which have important implications on stress management.

Replicability of time-varying connectivity patterns in large resting state fMRI samples.

PubMed

Abrol, Anees; Damaraju, Eswar; Miller, Robyn L; Stephen, Julia M; Claus, Eric D; Mayer, Andrew R; Calhoun, Vince D

2017-12-01

The past few years have seen an emergence of approaches that leverage temporal changes in whole-brain patterns of functional connectivity (the chronnectome). In this chronnectome study, we investigate the replicability of the human brain's inter-regional coupling dynamics during rest by evaluating two different dynamic functional network connectivity (dFNC) analysis frameworks using 7 500 functional magnetic resonance imaging (fMRI) datasets. To quantify the extent to which the emergent functional connectivity (FC) patterns are reproducible, we characterize the temporal dynamics by deriving several summary measures across multiple large, independent age-matched samples. Reproducibility was demonstrated through the existence of basic connectivity patterns (FC states) amidst an ensemble of inter-regional connections. Furthermore, application of the methods to conservatively configured (statistically stationary, linear and Gaussian) surrogate datasets revealed that some of the studied state summary measures were indeed statistically significant and also suggested that this class of null model did not explain the fMRI data fully. This extensive testing of reproducibility of similarity statistics also suggests that the estimated FC states are robust against variation in data quality, analysis, grouping, and decomposition methods. We conclude that future investigations probing the functional and neurophysiological relevance of time-varying connectivity assume critical importance. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Replicability of time-varying connectivity patterns in large resting state fMRI samples

PubMed Central

Abrol, Anees; Damaraju, Eswar; Miller, Robyn L.; Stephen, Julia M.; Claus, Eric D.; Mayer, Andrew R.; Calhoun, Vince D.

2018-01-01

The past few years have seen an emergence of approaches that leverage temporal changes in whole-brain patterns of functional connectivity (the chronnectome). In this chronnectome study, we investigate the replicability of the human brain’s inter-regional coupling dynamics during rest by evaluating two different dynamic functional network connectivity (dFNC) analysis frameworks using 7 500 functional magnetic resonance imaging (fMRI) datasets. To quantify the extent to which the emergent functional connectivity (FC) patterns are reproducible, we characterize the temporal dynamics by deriving several summary measures across multiple large, independent age-matched samples. Reproducibility was demonstrated through the existence of basic connectivity patterns (FC states) amidst an ensemble of inter-regional connections. Furthermore, application of the methods to conservatively configured (statistically stationary, linear and Gaussian) surrogate datasets revealed that some of the studied state summary measures were indeed statistically significant and also suggested that this class of null model did not explain the fMRI data fully. This extensive testing of reproducibility of similarity statistics also suggests that the estimated FC states are robust against variation in data quality, analysis, grouping, and decomposition methods. We conclude that future investigations probing the functional and neurophysiological relevance of time-varying connectivity assume critical importance. PMID:28916181

Youth Camp Safety & Health. Suggested State Statute & Regulations.

ERIC Educational Resources Information Center

Center for Disease Control (DHEW/PHS), Atlanta, GA.

To assist state regulatory agencies in development of comprehensive youth camp safety programs, this publication contains a brief suggested statute that could be used for initiation or modification of any state's youth camp safety programs and it outlines minimal regulations. Various categories of camps are covered--day, primitive, residential,…

Two-dimensional Fermi surfaces in Kondo insulating SmB6

NASA Astrophysics Data System (ADS)

Li, Gang

There has been renewed interest in Samarium Hexaboride, which is a strongly correlated heavy Fermion material. Hybridization between itinerant electrons and localized orbitals lead to an opening of charge gap at low temperature. However, the resistivity of SmB6 does not diverge at low temperature. Former studies suggested that this residual conductance is contributed by various origins. Recent theoretical developments suggest that the particular symmetry of energy bands of SmB6 may host a topologically non-trivial surface state, i.e., a topological Kondo insulator. To probe the Fermiology of the possible metallic surface state, we use sensitive torque magnetometry to detect the de Haas van Alphen (dHvA) effect due to Landau level quantization on flux-grown crystals, down to He-3 temperature and up to 45 Tesla. Our angular and temperature dependent data suggest two-dimensional Fermi Surfaces lie in both crystalline (001) and (101) surface planes of SmB6.

Brain Connectivity and Visual Attention

PubMed Central

Parks, Emily L.

2013-01-01

Abstract Emerging hypotheses suggest that efficient cognitive functioning requires the integration of separate, but interconnected cortical networks in the brain. Although task-related measures of brain activity suggest that a frontoparietal network is associated with the control of attention, little is known regarding how components within this distributed network act together or with other networks to achieve various attentional functions. This review considers both functional and structural studies of brain connectivity, as complemented by behavioral and task-related neuroimaging data. These studies show converging results: The frontal and parietal cortical regions are active together, over time, and identifiable frontoparietal networks are active in relation to specific task demands. However, the spontaneous, low-frequency fluctuations of brain activity that occur in the resting state, without specific task demands, also exhibit patterns of connectivity that closely resemble the task-related, frontoparietal attention networks. Both task-related and resting-state networks exhibit consistent relations to behavioral measures of attention. Further, anatomical structure, particularly white matter pathways as defined by diffusion tensor imaging, places constraints on intrinsic functional connectivity. Lastly, connectivity analyses applied to investigate cognitive differences across individuals in both healthy and diseased states suggest that disconnection of attentional networks is linked to deficits in cognitive functioning, and in extreme cases, to disorders of attention. Thus, comprehensive theories of visual attention and their clinical translation depend on the continued integration of behavioral, task-related neuroimaging, and brain connectivity measures. PMID:23597177

Associations between active shooter incidents and gun ownership and storage among families with young children in the United States.

PubMed

Morrissey, Taryn W

2017-07-01

The presence of firearms and their unsafe storage in the home can increase risk of firearm-related death and injury, but public opinion suggests that firearm ownership is a protective factor against gun violence. This study examined the effects of a recent nearby active shooter incident on gun ownership and storage practices among families with young children. A series of regression models, with data from the nationally representative Early Childhood Longitudinal Study-Birth Cohort merged with the FBI's Active Shooter Incidents data collected in 2003-2006, were used to examine whether household gun ownership and storage practices differed in the months prior to and following an active shooter incident that occurred anywhere in the United States or within the same state. Approximately one-fifth of young children lived in households with one or more guns; of these children, only two-thirds lived in homes that stored all guns in locked cabinets. Results suggest that the experience of a recent active shooter incident was associated with an increased likelihood of storing all guns locked, with the magnitude dependent on the temporal and geographic proximity of the incident. The severity of the incident, defined as the number of fatalities, predicted an increase in storing guns locked. Findings suggest that public shootings change behaviors related to firearm storage among families with young children. Copyright © 2017 Elsevier Inc. All rights reserved.

Topological Magnon Bands and Unconventional Superconductivity in Pyrochlore Iridate Thin Films.

PubMed

Laurell, Pontus; Fiete, Gregory A

2017-04-28

We theoretically study the magnetic properties of pyrochlore iridate bilayer and trilayer thin films grown along the [111] direction using a strong coupling approach. We find the ground state magnetic configurations on a mean field level and carry out a spin-wave analysis about them. In the trilayer case the ground state is found to be the all-in-all-out (AIAO) state, whereas the bilayer has a deformed AIAO state. For all parameters of the spin-orbit coupled Hamiltonian we study, the lowest magnon band in the trilayer case has a nonzero Chern number. In the bilayer case we also find a parameter range with nonzero Chern numbers. We calculate the magnon Hall response for both geometries, finding a striking sign change as a function of temperature. Using a slave-boson mean-field theory we study the doping of the trilayer system and discover an unconventional time-reversal symmetry broken d+id superconducting state. Our study complements prior work in the weak coupling limit and suggests that the [111] grown thin film pyrochlore iridates are a promising candidate for topological properties and unconventional orders.

The political economy of oil and the Niger Delta crisis

NASA Astrophysics Data System (ADS)

Ighodaro, Osaro O.

This study is about the burgeoning crisis in Nigeria's Oil Producing Niger Delta region. Discerning the intersecting contributive factors to the crisis, this dissertation suggests that the Niger Delta crisis is symptomatic of challenges to development in Nigeria. Due to the insidious colonial/neo-colonial practices of subjugation, and exploitation of the host communities, it is suggested that the extractive, super-profit motive of Shell, the concomitant environmental degradation, corruption of a bellicose state, ethnic conflict and suffering of the masses are outcomes of a long historically debilitating relationship with international capital which causes irreparable retardation to the host communities. From cash crop economy to a mono-oil economy resources are removed from the communities and used to enhance the colonial state and their post-colonial harbingers of misery. Hence, the indigenous people claim that the Niger Delta is in a crisis, and they are willing to confront the triple alliance of multinational oil companies like Shell, the Nigerian State and the local elite so long as these allies of subjugation continue to neglect the goose that lays the proverbial golden egg (oil that is). Theoretically, a hybrid Political Economy approach was adopted as the over-aching framework for the study, while Dependency theory, modified by what I have called African Transformative scholarly perspective, served as the conceptual tool. Primary and secondary sources of data, including personal observation, interviews, official government documents and other publications were utilized for this analysis. In view of recommendations, it is suggested that first, the Nigerian state should assume decisive and unflinching leadership in holding oil companies responsible for their activities in the host communities; second, oil companies (like Shell) should see themselves as an integral part of the host communities; invest in their development by providing employment opportunities and adhering to humane environmental practices. Finally, I suggest that the ownership and control of all resources, including oil should be vested in those communities in which they are found. The revenues accruing to the constitutive states of Nigeria will be accordingly taxed with the revenues from the taxes utilized for the general good of the polity especially the less endowed communities.

The Wax and Wane of Narcissism: Grandiose Narcissism as a Process or State.

PubMed

Giacomin, Miranda; Jordan, Christian H

2016-04-01

Though grandiose narcissism has predominantly been studied in structural terms-focused on individuals' general tendencies to be more or less narcissistic-we tested whether it also has a meaningful process or state component. Using a daily diary study methodology and multilevel modeling (N = 178 undergraduates, 146 female; Mage  = 18.86, SD = 2.21), we examine whether there is significant variability in daily state narcissism and whether this variability relates systematically to other psychological states (i.e., self-esteem, stress) and daily events. We assessed state narcissism and daily experiences over a 10-day period. We observed significant within-person variability in daily narcissism. Notably, this variability was not simply random error, as it related systematically to other psychological states and daily events. Specifically, state narcissism was higher when people experienced more positive agentic outcomes (e.g., having power over someone) or more positive communal outcomes (e.g., helping someone with a problem). State narcissism was lower on days people experienced greater felt stress. These relations held when state self-esteem, gender, and trait narcissism were controlled. These findings suggest that grandiose narcissism has a meaningful process or state component. © 2014 Wiley Periodicals, Inc.

Bipolar mood state reflected in cortico-amygdala resting state connectivity: A cohort and longitudinal study.

PubMed

Brady, Roscoe O; Margolis, Allison; Masters, Grace A; Keshavan, Matcheri; Öngür, Dost

2017-08-01

Using resting-state functional magnetic resonance imaging (rsfMRI), we previously compared cohorts of bipolar I subjects in a manic state to those in a euthymic state to identify mood state-specific patterns of cortico-amygdala connectivity. Our results suggested that mania is reflected in the disruption of emotion regulation circuits. We sought to replicate this finding in a group of subjects with bipolar disorder imaged longitudinally across states of mania and euthymia METHODS: We divided our subjects into three groups: 26 subjects imaged in a manic state, 21 subjects imaged in a euthymic state, and 10 subjects imaged longitudinally across both mood states. We measured differences in amygdala connectivity between the mania and euthymia cohorts. We then used these regions of altered connectivity to examine connectivity in the longitudinal bipolar group using a within-subjects design. Our findings in the mania vs euthymia cohort comparison were replicated in the longitudinal analysis. Bipolar mania was differentiated from euthymia by decreased connectivity between the amygdala and pre-genual anterior cingulate cortex. Mania was also characterized by increased connectivity between amygdala and the supplemental motor area, a region normally anti-correlated to the amygdala in emotion regulation tasks. Stringent controls for movement effects limited the number of subjects in the longitudinal sample. In this first report of rsfMRI conducted longitudinally across mood states, we find that previously observed between-group differences in amygdala connectivity are also found longitudinally within subjects. These results suggest resting state cortico-amygdala connectivity is a biomarker of mood state in bipolar disorder. Copyright © 2017 Elsevier B.V. All rights reserved.

Quench dynamics of the spin-imbalanced Fermi-Hubbard model in one dimension

NASA Astrophysics Data System (ADS)

Yin, Xiao; Radzihovsky, Leo

2016-12-01

We study a nonequilibrium dynamics of a one-dimensional spin-imbalanced Fermi-Hubbard model following a quantum quench of on-site interaction, realizable, for example, in Feshbach-resonant atomic Fermi gases. We focus on the post-quench evolution starting from the initial BCS and Fulde-Ferrell-Larkin-Ovchinnikov (FFLO) ground states and analyze the corresponding spin-singlet, spin-triplet, density-density, and magnetization-magnetization correlation functions. We find that beyond a light-cone crossover time, rich post-quench dynamics leads to thermalized and pre-thermalized stationary states that display strong dependence on the initial ground state. For initially gapped BCS state, the long-time stationary state resembles thermalization with the effective temperature set by the initial value of the Hubbard interaction. In contrast, while the initial gapless FFLO state reaches a stationary pre-thermalized form, it remains far from equilibrium. We suggest that such post-quench dynamics can be used as a fingerprint for identification and study of the FFLO phase.

Opportunities for State-Level Action to Reduce Firearm Violence: Proceeding From the Evidence

PubMed Central

Braga, Anthony A.

2011-01-01

Firearm violence remains an important problem, and a large body of evidence shows that guns used in crime follow generally predictable paths from manufacturer to criminal end user. Policy initiatives based on that evidence have been shown to be effective. A recently published study conducted by a leading policy organization presents new evidence and makes specific recommendations for action by state-level policymakers. Unfortunately, the study's analysis is overly simplified, and the recommendations are therefore misleading. We suggest alternatives that are evidence based. PMID:21778510

Concepts in context: Processing mental state concepts with internal or external focus involves different neural systems

PubMed Central

Oosterwijk, Suzanne; Mackey, Scott; Wilson-Mendenhall, Christine; Winkielman, Piotr; Paulus, Martin P.

2015-01-01

According to embodied cognition theories concepts are contextually-situated and grounded in neural systems that produce experiential states. This view predicts that processing mental state concepts recruits neural regions associated with different aspects of experience depending on the context in which people understand a concept. This neuroimaging study tested this prediction using a set of sentences that described emotional (e.g., fear, joy) and non-emotional (e.g., thinking, hunger) mental states with internal focus (i.e. focusing on bodily sensations and introspection) or external focus (i.e. focusing on expression and action). Consistent with our predictions, data suggested that the inferior frontal gyrus, a region associated with action representation, was engaged more by external than internal sentences. By contrast, the ventromedial prefrontal cortex, a region associated with the generation of internal states, was engaged more by internal emotion sentences than external sentence categories. Similar patterns emerged when we examined the relationship between neural activity and independent ratings of sentence focus. Furthermore, ratings of emotion were associated with activation in the medial prefrontal cortex, whereas ratings of activity were associated with activation in the inferior frontal gyrus. These results suggest that mental state concepts are represented in a dynamic way, using context-relevant interoceptive and sensorimotor resources. PMID:25748274

Feeling Better When Someone Is Alike: Poor Emotion Regulators Profit From Pro-Social Values and Priming for Similarities With Close Others.

PubMed

Chatterjee, Monischa B; Baumann, Nicola; Koole, Sander L

2017-12-01

The dispositional inability to self-regulate one's own emotions intuitively is described as state orientation and has been associated with numerous psychological impairments. The necessity to search for buffering effects against negative outcomes of state orientation is evident. Research suggests that state-oriented individuals can benefit from feeling close to others. Yet, there are individual differences in the extent to which supportive relationships are valued. The objective of the present article was to examine whether high importance of relatedness increases the utilization of its situational activation among state-oriented individuals. In two studies, we examined whether situational activation of relatedness (by priming for similarities with a close other) is particularly advantageous for state-oriented individuals who attach high importance to relatedness (i.e., benevolence values). The sample consisted of 170 psychology undergraduates in Study 1 and 177 in Study 2. In both studies, state-oriented participants high in benevolence had reduced negative mood after thinking about similarities (vs. differences). State-oriented participants low in benevolence did not benefit from priming for similarities. In Study 2, physical presence of a close other did not boost priming effects for state-oriented participants but stimulated action-oriented participants to attune their self-regulatory efforts to the context. The results show that state-oriented individuals who value benevolence do benefit from a situational activation of relatedness. © 2016 Wiley Periodicals, Inc.

Dwarf mistletoe effects on fuel loadings in ponderosa pine forests in northern Arizona

Treesearch

Chad Hoffman; Robert Mathiasen; Carolyn Hull Sieg

2007-01-01

Southwestern dwarf mistletoe (Arceuthobium vaginatum (Willd.) J. Presl ssp. cryptopodum) infests about 0.9 million ha in the southwestern United States. Several studies suggest that dwarf mistletoes affect forest fuels and fire behavior; however, few studies have quantified these effects. We compared surface fuel loadings and...

Dietary Precursors of Serotonin and Newborn State Behavior.

ERIC Educational Resources Information Center

Yogman, Michael W.; Zeisel, Steven

Although previous research with adult humans and nonhumans has suggested a relationship between sleep behavior and brain serotonin levels, no studies have been made of the relationship of normal children's or infants' sleep patterns to serotonin levels, tryptophan metabolism, or diet. This study investigates the relationship between dietary…

A Framework for the Study of Emotions in Organizational Contexts.

ERIC Educational Resources Information Center

Fiebig, Greg V.; Kramer, Michael W.

1998-01-01

Approaches the study of emotions in organizations holistically, based on a proposed framework. Provides descriptive data that suggests the presence of the framework's major elements. States that future examination of emotions based on this framework should assist in understanding emotions, which are frequently ignored in a rational model. (PA)

Report of the Virginia Traffic Records Feasibility Study Team to the State Traffic Records Committee.

DOT National Transportation Integrated Search

1973-01-01

The purpose of the study was to define the current traffic records system of the Commonwealth so as to identify deficiencies as specifically as possible; to suggest changes to upgrade the system to meet current and projected demands at maximum effici...

Study of magnetoresistance in the supercooled state of Dy-Y alloys

NASA Astrophysics Data System (ADS)

Jena, Rudra Prasad; Lakhani, Archana

2018-02-01

We report the magnetoresistance studies on Dy1-xYx (x ≤ 0.05) alloys across the first order helimagnetic to ferromagnetic phase transition. These alloys exhibit multiple magnetic phases on varying the temperature and magnetic field. The magnetoresistance studies in the hysteresis region shows irreversibility in forward and reverse field cycles. The resistivity values at zero field for these alloys after zero field cooling to the measurement temperatures, are different in both forward and reverse field cycles. The path dependence of magnetoresistance suggests the presence of helimagnetic phase as the supercooled metastable state which transforms to the stable ferromagnetic state on increasing the field. At high magnetic fields negative magnetoresistance following a linear dependence with field is observed which is attributed to the magnon scattering.

Ground-state and Thermodynamic Properties of an S = 1 Kitaev Model

NASA Astrophysics Data System (ADS)

Koga, Akihisa; Tomishige, Hiroyuki; Nasu, Joji

2018-06-01

We study the ground-state and thermodynamic properties of an S = 1 Kitaev model. We first clarify the existence of global parity symmetry in addition to the local symmetry on each plaquette, which enables us to perform large-scale calculations on up to 24 sites. It is found that the ground state should be singlet, and its energy is estimated as E/N ˜ -0.65J, where J is the Kitaev exchange coupling. We find that the lowest excited state belongs to the same subspace as the ground state, and that the gap decreases monotonically with increasing system size, which suggests that the ground state of the S = 1 Kitaev model is gapless. Using the thermal pure quantum states, we clarify the finite temperature properties characteristic of the Kitaev models with S ≤ 2.

Win some, lose some: parental hypertension and heart rate change in an incentive versus response cost paradigm.

PubMed

Hastrup, J L; Johnson, C A; Hotchkiss, A P; Kraemer, D L

1986-11-01

Fowles (1983), citing evidence from separate studies, suggests that both incentive and response cost paradigms increase heart rate and should be subsumed under Gray's (1975) 'appetitive motivational system'. Shock avoidance and loss of reward (response cost) contingencies, while aversive, appear to evoke this motivational system; consequently both should elicit heart rate increases independent of anxiety. The present investigation compared magnitude of heart rate changes observed under conditions of winning and losing money. Results showed: no differences between incentive and response cost conditions; no effect of state anxiety on heart rate in these conditions, despite an elevation of state anxiety on the task day relative to a subsequent relaxation day assessment; and some evidence for the presence under both such appetitive conditions of cardiovascular hyperresponsivity among offspring of hypertensive parents. The results suggest a need for systematic parametric studies of experimental conditions.

Improving Direct-Care Compensation in Nursing Homes: Medicaid Wage Pass-through Adoption, 1999 – 2004

PubMed Central

Miller, Edward Alan; Wang, Lili; Feng, Zhanlian; Mor, Vincent

2013-01-01

Because states play such a prominent role in the U.S. health care system, they have long grappled with how to best control health care costs while maintaining high quality of care. There are many policy tools available to address efficiency and quality concerns — from pure state regulation to market-oriented competition designs. Given public discourse and official party platforms, one would assume that states controlled by Democrats would be more likely to adopt regulatory reforms. This study examines whether party control, as well as other economic and political factors, is associated with adopting wage pass-through (WPT) policies, which direct a portion of Medicaid reimbursement or its increase toward nursing home staff in an effort to reduce staff turnover, thereby increasing efficiency and the quality of care provided. Contrary to expectations, results indicate that states with Republican governors were against WPT adoption only when for-profit industry pressure increased; otherwise, they were more likely to favor adoption than their Democratic counterparts. This suggests a more complex relationship between partisanship and state-level policy adoption than is typically assumed. Results also indicate that state officials reacted predictably to prevailing political and economic conditions affecting state fiscal-year decisions but required sufficient governing capacity to successfully integrate WPTs into existing reimbursement system arrangements. This suggests that WPTs represent a hybrid between comprehensive and incremental policy change. PMID:22323236

The impact of negative emotions on self-concept abstraction depends on accessible information processing styles.

PubMed

Isbell, Linda M; Rovenpor, Daniel R; Lair, Elicia C

2016-10-01

Research suggests that anger promotes global, abstract processing whereas sadness and fear promote local, concrete processing (see Schwarz & Clore, 2007 for a review). Contrary to a large and influential body of work suggesting that specific affective experiences are tethered to specific cognitive outcomes, the affect-as-cognitive-feedback account maintains that affective experiences confer positive or negative value on currently dominant processing styles, and thus can lead to either global or local processing (Huntsinger, Isbell, & Clore, 2014). The current work extends this theoretical perspective by investigating the impact of discrete negative emotions on the self-concept. By experimentally manipulating information processing styles and discrete negative emotions that vary in appraisals of certainty, we demonstrate that the impact of discrete negative emotions on the spontaneous self-concept depends on accessible processing styles. When global processing was accessible, individuals in angry (negative, high certainty) states generated more abstract statements about themselves than individuals in either sad (Experiment 1) or fearful (Experiment 2; negative, low certainty) states. When local processing was made accessible, however, the opposite pattern emerged, whereby individuals in angry states generated fewer abstract statements than individuals in sad or fearful states. Together these studies provide new insights into the mechanisms through which discrete emotions influence cognition. In contrast to theories assuming a dedicated link between emotions and processing styles, these results suggest that discrete emotions provide feedback about accessible ways of thinking, and are consistent with recent evidence suggesting that the impact of affect on cognition is highly context-dependent. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Affective states and adaptation to parabolic flights

NASA Astrophysics Data System (ADS)

Collado, Aurélie; Langlet, Cécile; Tzanova, Tzvetomira; Hainaut, Jean-Philippe; Monfort, Vincent; Bolmont, Benoît

2017-05-01

This exploratory study investigates (i) inter-individual variations of affective states before a parabolic flight (i.e., PF) on the basis of quality of adaptation to physical demands, and (ii) intra-individual variations of affective states during a PF. Mood-states, state-anxiety and salivary cortisol were assessed in two groups with a different quality of adaptation (an Adaptive Group, i.e., AG, and a Maladaptive Group, i.e., MG) before and during a PF. Before PF, MG scored higher on mood states (Anger-Hostility, Fatigue-Inertia) than AG. During the flight, while AG seemed to present "normal" affective responses to the demanding environment (e.g., increase in salivary cortisol), MG presented increases in mood states such as Confusion-Bewilderment or Tension-Anxiety. The findings suggest that the psychological states of MG could have disturbed their ability to integrate sensory information from an unusual environment, which led to difficulties in coping with the physical demands of PF.

Conformational states of the full-length glucagon receptor

PubMed Central

Yang, Linlin; Yang, Dehua; de Graaf, Chris; Moeller, Arne; West, Graham M.; Dharmarajan, Venkatasubramanian; Wang, Chong; Siu, Fai Y.; Song, Gaojie; Reedtz-Runge, Steffen; Pascal, Bruce D.; Wu, Beili; Potter, Clinton S.; Zhou, Hu; Griffin, Patrick R.; Carragher, Bridget; Yang, Huaiyu; Wang, Ming-Wei; Stevens, Raymond C.; Jiang, Hualiang

2015-01-01

Class B G protein-coupled receptors are composed of an extracellular domain (ECD) and a seven-transmembrane (7TM) domain, and their signalling is regulated by peptide hormones. Using a hybrid structural biology approach together with the ECD and 7TM domain crystal structures of the glucagon receptor (GCGR), we examine the relationship between full-length receptor conformation and peptide ligand binding. Molecular dynamics (MD) and disulfide crosslinking studies suggest that apo-GCGR can adopt both an open and closed conformation associated with extensive contacts between the ECD and 7TM domain. The electron microscopy (EM) map of the full-length GCGR shows how a monoclonal antibody stabilizes the ECD and 7TM domain in an elongated conformation. Hydrogen/deuterium exchange (HDX) studies and MD simulations indicate that an open conformation is also stabilized by peptide ligand binding. The combined studies reveal the open/closed states of GCGR and suggest that glucagon binds to GCGR by a conformational selection mechanism. PMID:26227798

Thermal unfolding of tetrameric melittin: comparison with the molten globule state of cytochrome c.

PubMed Central

Hagihara, Y.; Oobatake, M.; Goto, Y.

1994-01-01

Whereas melittin at micromolar concentrations is unfolded under conditions of low salt at neutral pH, it transforms to a tetrameric alpha-helical structure under several conditions, such as high peptide concentration, high anion concentration, or alkaline pH. The anion- and pH-dependent stabilization of the tetrameric structure is similar to that of the molten globule state of several acid-denatured proteins, suggesting that tetrameric melittin might be a state similar to the molten globule state. To test this possibility, we studied the thermal unfolding of tetrameric melittin using far-UV CD and differential scanning calorimetry. The latter technique revealed a broad but distinct heat absorption peak. The heat absorption curves were consistent with the unfolding transition observed by CD and were explainable by a 2-state transition mechanism between the tetrameric alpha-helical state and the monomeric unfolded state. From the peptide or salt-concentration dependence of unfolding, the heat capacity change upon unfolding was estimated to be 5 kJ (mol of tetramer)-1 K-1 at 30 degrees C and decreased with increasing temperature. The observed change in heat capacity was much smaller than that predicted from the crystallographic structure (9.2 kJ (mol of tetramer)-1 K-1), suggesting that the hydrophobic residues of tetrameric melittin in solution are exposed in comparison with the crystallographic structure. However, the results also indicate that the structure is more ordered than that of a typical molten globule state. We consider that the conformation is intermediate between the molten globule state and the native state of globular proteins. PMID:7833804

Negative functional coupling between the right fronto-parietal and limbic resting state networks predicts increased self-control and later substance use onset in adolescence.

PubMed

Lee, Tae-Ho; Telzer, Eva H

2016-08-01

Recent developmental brain imaging studies have demonstrated that negatively coupled prefrontal-limbic circuitry implicates the maturation of brain development in adolescents. Using resting-state functional magnetic resonance imaging (rs-fMRI) and independent component analysis (ICA), the present study examined functional network coupling between prefrontal and limbic systems and links to self-control and substance use onset in adolescents. Results suggest that negative network coupling (anti-correlated temporal dynamics) between the right fronto-parietal and limbic resting state networks is associated with greater self-control and later substance use onset in adolescents. These findings increase our understanding of the developmental importance of prefrontal-limbic circuitry for adolescent substance use at the resting-state network level. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Mental Contrasting of a Negative Future with a Positive Reality Regulates State Anxiety

PubMed Central

Brodersen, Gunnar; Oettingen, Gabriele

2017-01-01

Mental contrasting of a desired future with impeding reality is a self-regulatory strategy fostering goal pursuit. However, there is little research on mental contrasting of a negative future with a positive reality. We conducted two experiments, each with four experimental conditions, investigating the effects of mental contrasting a negative future with a positive reality on state anxiety: participants who mentally contrasted a negative future regarding a bacterial epidemic (Study 1, N = 199) or an idiosyncratic negative event (Study 2, N = 206) showed less state anxiety than participants who imagined the negative future only or who reverse contrasted; participants who mentally elaborated on the positive reality also showed less state anxiety. Our findings suggest that mental contrasting of a negative future helps people reduce disproportional anxiety regarding a negative future. PMID:28979223

The effects of disulfide bonds on the denatured state of barnase.

PubMed Central

Clarke, J.; Hounslow, A. M.; Bond, C. J.; Fersht, A. R.; Daggett, V.

2000-01-01

The effects of engineered disulfide bonds on protein stability are poorly understood because they can influence the structure, dynamics, and energetics of both the native and denatured states. To explore the effects of two engineered disulfide bonds on the stability of barnase, we have conducted a combined molecular dynamics and NMR study of the denatured state of the two mutants. As expected, the disulfide bonds constrain the denatured state. However, specific extended beta-sheet structure can also be detected in one of the mutant proteins. This mutant is also more stable than would be predicted. Our study suggests a possible cause of the very high stability conferred by this disulfide bond: the wild-type denatured ensemble is stabilized by a nonnative hydrophobic cluster, which is constrained from occurring in the mutant due to the formation of secondary structure. PMID:11206061

Implications of Climate Change for State Bioassessment ...

EPA Pesticide Factsheets

This draft report uses biological data collected by four states in wadeable rivers and streams to examine the components of state and tribal bioassessment and biomonitoring programs that may be vulnerable to climate change. The study investigates the potential to identify biological response signals to climate change within existing bioassessment data sets; analyzes how biological responses can be categorized and interpreted; and assesses how they may influence decision-making processes. The analyses suggest that several biological indicators may be used to detect climate change effects and such indicators can be used by state bioassessment programs to document changes at high-quality reference sites. The study investigates the potential to identify biological response signals to climate change within existing bioassessment data sets; analyzes how biological responses can be categorized and interpreted; and assesses how they may influence decision-making processes.

Alternative ground states enable pathway switching in biological electron transfer

DOE PAGES

Abriata, Luciano A.; Alvarez-Paggi, Damian; Ledesma, Gabirela N.; ...

2012-10-10

Electron transfer is the simplest chemical reaction and constitutes the basis of a large variety of biological processes, such as photosynthesis and cellular respiration. Nature has evolved specific proteins and cofactors for these functions. The mechanisms optimizing biological electron transfer have been matter of intense debate, such as the role of the protein milieu between donor and acceptor sites. Here we propose a mechanism regulating long-range electron transfer in proteins. Specifically, we report a spectroscopic, electrochemical, and theoretical study on WT and single-mutant CuA redox centers from Thermus thermophilus, which shows that thermal fluctuations may populate two alternative ground-state electronicmore » wave functions optimized for electron entry and exit, respectively, through two different and nearly perpendicular pathways. In conclusion, these findings suggest a unique role for alternative or “invisible” electronic ground states in directional electron transfer. Moreover, it is shown that this energy gap and, therefore, the equilibrium between ground states can be fine-tuned by minor perturbations, suggesting alternative ways through which protein–protein interactions and membrane potential may optimize and regulate electron–proton energy transduction.« less

Optimal control theory with continuously distributed target states: An application to NaK

NASA Astrophysics Data System (ADS)

Kaiser, Andreas; May, Volkhard

2006-01-01

Laser pulse control of molecular dynamics is studied theoretically by using optimal control theory. The control theory is extended to target states which are distributed in time as well as in a space of parameters which are responsible for a change of individual molecular properties. This generalized treatment of a control task is first applied to wave packet formation in randomly oriented diatomic systems. Concentrating on an ensemble of NaK molecules which are not aligned the control yield decreases drastically when compared with an aligned ensemble. Second, we demonstrate for NaK the maximization of the probe pulse transient absorption in a pump-probe scheme with an optimized pump pulse. These computations suggest an overall optical control scheme, whereby a flexible technique is suggested to form particular wave packets in the excited state potential energy surface. In particular, it is shown that considerable wave packet localization at the turning points of the first-excited Σ-state potential energy surfaces of NaK may be achieved. The dependency of the control yield on the probe pulse parameters is also discussed.

Interaction of thyroid state and denervation on skeletal myosin heavy chain expression

NASA Technical Reports Server (NTRS)

Haddad, F.; Arnold, C.; Zeng, M.; Baldwin, K.

1997-01-01

The goal of this study was to examine the effects of altered thyroid state and denervation (Den) on skeletal myosin heavy chain (MHC) expression in the plantaris and soleus muscles. Rats were subjected to unilateral denervation (Den) and randomly assigned to one of three groups: (1) euthyroid; (2) hyperthyroid; (3) and hypothyroid. Denervation caused severe muscle atrophy and muscle-type specific MHC transformation. Denervation transformed the soleus to a faster muscle, and its effects required the presence of circulating thyroid hormone. In contrast, denervation transformed the plantaris to a slower muscle independently of thyroid state. Furthermore, thyroid hormone effects did not depend upon innervation status in the soleus, while they required the presence of the nerve in the plantaris. Collectively, these findings suggest that both thyroid hormone and intact nerve (a) differentially affect MHC transformations in fast and slow muscle; and (b) are important factors in regulating the optimal expression of both type I and IIB MHC genes. This research suggests that for patients with nerve damage and/or paralysis, both muscle mass and biochemical properties can also be affected by the thyroid state.

The beta-delayed particle decay of neon-17

NASA Astrophysics Data System (ADS)

Morton, Anthony Colin

2001-10-01

An experiment has been proposed to study the β- delayed proton decay of 17Ne into α- particle-emitting states in 16O below the 12C + α threshold in the hopes of using the information gained to constrain the 12C(α, γ) 16O cross section at stellar energies; several experiments have been carried out using the TISOL facility at TRIUMF in an effort to determine the feasibility of such an approach. 17Ne decays by β-particle emission to excited states in 17F; by studying proton-γ-ray coincidences in the decay of these states, relative branching ratios have been obtained for the β-delayed proton decay of 17Ne to γ-ray-emitting states in 16O. These indicate that the decay of the isobaric analogue state (IAS) at 11.1929 MeV in 17F to the 2 + subthreshold state at 6.917 MeV in 16O is a factor of thirty weaker than that of the IAS to any other γ- emitting state. From measurements of the angular correlations observed in such coincidences, the spins and parities of several excited states in 17F have been determined; it has also been shown that the decay of the IAS to the 1 - subthreshold state at 7.117 MeV in 16O is strongly anisotropic, suggesting that it has a strong l = 2 component. Further decay studies have yielded a comprehensive set of β-delayed particle branching ratios from the decay of 17Ne; from these, fAt values and reduced Gamow-Teller matrix elements have been calculated, and the Fermi decay strength of the IAS has been limited to >=2.96 +/- 0.14 indicating a T = / isospin purity of >=98.7 +/- 4.6% for the IAS. The results obtained suggest that a determination of both the E1 and E2 components of the 12C(α, γ) 16O cross section is not feasible; however, with improved yields of 17Ne, a determination of only the E1 component should be.

EEG Correlates of the Flow State: A Combination of Increased Frontal Theta and Moderate Frontocentral Alpha Rhythm in the Mental Arithmetic Task.

PubMed

Katahira, Kenji; Yamazaki, Yoichi; Yamaoka, Chiaki; Ozaki, Hiroaki; Nakagawa, Sayaka; Nagata, Noriko

2018-01-01

Flow experience is a subjective state experienced during holistic involvement in a certain activity, which has been reported to function as a factor promoting motivation, skill development, and better performance in the activity. To verify the positive effects of flow and develop a method to utilize it, the establishment of a reliable measurement of the flow state is essential. The present study utilized an electroencephalogram (EEG) during an experimentally evoked flow state and examined the possibility of objective measurement of immediate flow. A total of 16 participants (10 males, 6 females) participated in the experiment that employed a mental arithmetic task developed in a previous study. Post-trial self-report of the flow state and EEG during task execution were measured and compared among three conditions (Boredom, Flow, and Overload) that had different levels of task difficulty. Furthermore, the correlations between subjective flow items and EEG activity were examined. As expected, the ratings on the subjective evaluation items representing the flow state were the highest in the Flow condition. Regarding the EEG data, theta activities in the frontal areas were higher in the Flow and the Overload conditions than in the Boredom condition, and alpha activity in the frontal areas and the right central area gradually increased depending on the task difficulty. These EEG activities correlated with self-reported flow experience, especially items related to the concentration on the task and task difficulty. From the results, the flow state was characterized by increased theta activities in the frontal areas and moderate alpha activities in the frontal and central areas. The former may be related to a high level of cognitive control and immersion in task, and the latter suggests that the load on the working memory was not excessive. The findings of this study suggest the possibility of distinguishing the flow state from other states using multiple EEG activities and indicate the need for other physiological indicators corresponding to the other aspects of flow experience.

EEG Correlates of the Flow State: A Combination of Increased Frontal Theta and Moderate Frontocentral Alpha Rhythm in the Mental Arithmetic Task

PubMed Central

Katahira, Kenji; Yamazaki, Yoichi; Yamaoka, Chiaki; Ozaki, Hiroaki; Nakagawa, Sayaka; Nagata, Noriko

2018-01-01

Flow experience is a subjective state experienced during holistic involvement in a certain activity, which has been reported to function as a factor promoting motivation, skill development, and better performance in the activity. To verify the positive effects of flow and develop a method to utilize it, the establishment of a reliable measurement of the flow state is essential. The present study utilized an electroencephalogram (EEG) during an experimentally evoked flow state and examined the possibility of objective measurement of immediate flow. A total of 16 participants (10 males, 6 females) participated in the experiment that employed a mental arithmetic task developed in a previous study. Post-trial self-report of the flow state and EEG during task execution were measured and compared among three conditions (Boredom, Flow, and Overload) that had different levels of task difficulty. Furthermore, the correlations between subjective flow items and EEG activity were examined. As expected, the ratings on the subjective evaluation items representing the flow state were the highest in the Flow condition. Regarding the EEG data, theta activities in the frontal areas were higher in the Flow and the Overload conditions than in the Boredom condition, and alpha activity in the frontal areas and the right central area gradually increased depending on the task difficulty. These EEG activities correlated with self-reported flow experience, especially items related to the concentration on the task and task difficulty. From the results, the flow state was characterized by increased theta activities in the frontal areas and moderate alpha activities in the frontal and central areas. The former may be related to a high level of cognitive control and immersion in task, and the latter suggests that the load on the working memory was not excessive. The findings of this study suggest the possibility of distinguishing the flow state from other states using multiple EEG activities and indicate the need for other physiological indicators corresponding to the other aspects of flow experience. PMID:29593605

The Locus of Career Vitality. ASHE 1983 Annual Meeting Paper.

ERIC Educational Resources Information Center

Toombs, William

The context for considering faculty career vitality is addressed. It is suggested that the unit of study should be individual, and that both internal and external influences should be considered. A contrasting view is that the institution should be the unit of study. A Pennsylvania State University study revealed that faculty career decisions were…

A Case Study: Achievement Studies of Persistent, Transitional, and Transient Populations within the Blitz Program Model at a Large Midwestern Elementary School

ERIC Educational Resources Information Center

Ramey, Jackie D.

2013-01-01

The United States' Public Education system shared concerns regarding declining achievement results across the nation. Numerous research studies suggested significant correlations to various variables, such as, SES (Socio-Economic Status), LEP (Limited English Proficiency), IEP (Individualized Educational Programs), ethnicity, and student mobility.…

A Multimethod Multitrait Validity Assessment of Self-Construal in Japan, Korea, and the United States

ERIC Educational Resources Information Center

Bresnahan, Mary J.; Levine, Timothy R.; Shearman, Sachiyo Morinaga; Lee, Sun Young; Park, Cheong-Yi; Kiyomiya, Toru

2005-01-01

A large number of previous studies have used self-construal to predict communication outcomes. Recent evidence, however, suggests that validity problems may exist in self-construal measurement. The current study conducted a multimethod multitrait (Campbell & Fiske, 1959) validation study of self-construal measures with data (total N = 578)…

Do International Studies Students Have a Broader Global Awareness than Other College Students?

ERIC Educational Resources Information Center

De Soto, William; Tajalli, Hassan; Villarreal, Alison

2016-01-01

Purpose: Common knowledge seem to suggest that international studies (IS) programs are at the forefront of helping their students better understand the world beyond United States borders. The purpose of this study is to test the proposition that IS students have a greater global awareness than other college students. Method: Hanvey's (1976) five…

Bipolar vulnerability and extreme appraisals of internal states: a computerized ratings study.

PubMed

Dodd, Alyson L; Mansell, Warren; Morrison, Anthony P; Tai, Sara

2011-01-01

A recent integrative cognitive model proposed that multiple, extreme, personalized, positive and negative appraisals of internal states predispose to maintain and exacerbate bipolar symptoms. This study aimed to directly assess conviction in a range of positive and negative appraisals of internal states suggested by the model, by using a laboratory-based computerized task. In a student sample (n = 68), a history of hypomania was associated with more positive and less negative appraisals of internal states, and a history of depression was associated with more negative appraisals and less positive appraisals of internal states. The sample was then split into three groups for comparison: bipolar risk (n = 18), depression risk (n = 20) and controls (n  = 30). Relative to controls, the bipolar risk group made more extreme ratings of catastrophic appraisals of low activation states and tended to make more extreme ratings of appraisals of high activation states. The depression risk group scored higher on a range of negative appraisals of low activation states. These findings provide tentative support for the role of both positive and negative, extreme, personalized appraisals of internal states in hypomania and depression. Copyright © 2011 John Wiley & Sons, Ltd.

Prediction of movement intention using connectivity within motor-related network: An electrocorticography study.

PubMed

Kang, Byeong Keun; Kim, June Sic; Ryun, Seokyun; Chung, Chun Kee

2018-01-01

Most brain-machine interface (BMI) studies have focused only on the active state of which a BMI user performs specific movement tasks. Therefore, models developed for predicting movements were optimized only for the active state. The models may not be suitable in the idle state during resting. This potential maladaptation could lead to a sudden accident or unintended movement resulting from prediction error. Prediction of movement intention is important to develop a more efficient and reasonable BMI system which could be selectively operated depending on the user's intention. Physical movement is performed through the serial change of brain states: idle, planning, execution, and recovery. The motor networks in the primary motor cortex and the dorsolateral prefrontal cortex are involved in these movement states. Neuronal communication differs between the states. Therefore, connectivity may change depending on the states. In this study, we investigated the temporal dynamics of connectivity in dorsolateral prefrontal cortex and primary motor cortex to predict movement intention. Movement intention was successfully predicted by connectivity dynamics which may reflect changes in movement states. Furthermore, dorsolateral prefrontal cortex is crucial in predicting movement intention to which primary motor cortex contributes. These results suggest that brain connectivity is an excellent approach in predicting movement intention.

REPORT OF THE SOUTHWEST TEXAS STATE COLLEGE RESEARCH CONFERENCE ON THE PROBLEM OF DYSLEXIA AND RELATED DISORDERS IN PUBLIC SCHOOLS OF THE UNITED STATES. REPORT OF THE WORKING GROUP ON TEACHER PREPARATION.

ERIC Educational Resources Information Center

ZEDLER, EMPRESS Y.

SOME GUIDELINES AND RECOMMENDATIONS FOR IMPROVING TEACHER EDUCATION IN ORDER TO MEET THE NEEDS OF SEVERELY DISABLED LEARNERS ARE PRESENTED. THE SUGGESTIONS INCLUDE IMPROVING PROFESSIONAL TRAINING FOR TEACHERS, PSYCHOLOGISTS, SUPERVISORS, AND COUNSELORS AT ALL LEVELS. TRAINING SHOULD INCLUDE THE STUDY OF DYSLEXIA AND THE PREPARATION OF A PILOT…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rao, G.S.J.; Cook, P.F.; Harris, B.G.

Treatment of the Ascaris suum phosphofructokinase (PFK) with 2{prime},3{prime}-dialdehyde ATP (oATP) results in an enzyme form that is inactive. The conformational integrity of the active site, however, is preserved, suggesting that oATP modification locks the PFK into an inactive T state that cannot be activated. A rapid, irreversible first-order inactivation of the PFK is observed in the presence of oATP. The rate of inactivation is saturable and gives a K{sub oATP} of 1.07 {plus minus} 0.27 mM. Complete protection against inactivation is afforded by high concentrations of ATP. This desensitized enzyme incorporates only 0.2-0.3 mol of ({sup 3}H)oATP/subunit, suggesting thatmore » in te native enzyme inactivation perhaps results from the modification of the ATP inhibitory site rather than the catalytic site. Modification of an active-site thiol by 4,4{prime}-dithiodipyridine is prevented yb ATP before and after oATP treatment. Finally, gel filtration HPLC studies show that the oATP-modified enzyme retains its tetrameric state and neither the tryptophan fluorescence nor the circular dichroic spectra of the modified enzyme are affected by fructose 2,6-bisphosphate, suggesting that the enzyme is locked into a tetrameric inactive T state.« less

Assessing the mean strength and variations of the time-to-time fluctuations of resting-state brain activity.

PubMed

Li, Zhengjun; Zang, Yu-Feng; Ding, Jianping; Wang, Ze

2017-04-01

The time-to-time fluctuations (TTFs) of resting-state brain activity as captured by resting-state fMRI (rsfMRI) have been repeatedly shown to be informative of functional brain structures and disease-related alterations. TTFs can be characterized by the mean and the range of successive difference. The former can be measured with the mean squared successive difference (MSSD), which is mathematically similar to standard deviation; the latter can be calculated by the variability of the successive difference (VSD). The purpose of this study was to evaluate both the resting state-MSSD and VSD of rsfMRI regarding their test-retest stability, sensitivity to brain state change, as well as their biological meanings. We hypothesized that MSSD and VSD are reliable in resting brain; both measures are sensitive to brain state changes such as eyes-open compared to eyes-closed condition; both are predictive of age. These hypotheses were tested with three rsfMRI datasets and proven true, suggesting both MSSD and VSD as reliable and useful tools for resting-state studies.

Crossing the Gender Gap: A Study of Female Participation and Performance in Advanced Maths and Sciences

NASA Astrophysics Data System (ADS)

Haseltine, Jessica

2006-10-01

A statistical analysis of enrollment in AP maths and sciences in the Abilene Independent School District, between 2000 and 2005, studied the relationship between gender, enrollment, and performance. Data suggested that mid-scoring females were less likely than their male counterparts to enroll in AP-level courses. AISD showed higher female : male score ratios than national and state averages but no improvement in enrollment comparisons. Several programs are suggested to improve both participation and performance of females in upper-level math and science courses.

Counter-current convection in a volcanic conduit

NASA Astrophysics Data System (ADS)

Fowler, A. C.; Robinson, Marguerite

2018-05-01

Volcanoes of Strombolian type are able to maintain their semi-permanent eruptive states through the constant convective recycling of magma within the conduit leading from the magma chamber. In this paper we study the form of this convection using an analytic model of degassing two-phase flow in a vertical channel. We provide solutions for the flow at small Grashof and large Prandtl numbers, and we suggest that permanent steady-state counter-current convection is only possible if an initial bubbly counter-current flow undergoes a régime transition to a churn-turbulent flow. We also suggest that the magma in the chamber must be under-pressured in order for the flow to be maintained, and that this compromises the assumed form of the flow.

Bovine tuberculosis: a retrospective study at Jos abattoir, Plateau State, Nigeria.

PubMed

Okeke, Lilian Akudo; Fawole, Olufunmilayo; Muhammad, Maryam; Okeke, Ikenna Osemeka; Nguku, Patrick; Wasswa, Peter; Dairo, David; Cadmus, Simeon

2016-01-01

Nigeria has the thirteenth highest burden of human tuberculosis. The current increasing incidence of tuberculosis in humans, particularly in immune-compromised persons, has given interest in the zoonotic importance of Mycobacterium bovis in developing countries like Nigeria. This study determined the prevalence of bovine tuberculosis as a background information for effective control measures in Plateau State in cattle population. We reviewed surveillance records on cattle slaughtered and suggestive tuberculosis lesions from cattle slaughtered annually from 2007-2012 in Jos abattoir, Plateau State. Bovine tuberculosis cases at post mortem were based on examination of characteristics TB lesion on organs by Veterinary officers. We performed descriptive analysis using Epi info version 3.5.3 and Microsoft Excel 2007. A total of 52, 262 cattle were slaughtered from 2007-2012, out of which 4, 658 (11.2%) had evidence of tuberculosis lesion at post mortem. The average yearly prevalence was 9.1% but varied from a high of 16.3% in 2007 to a low of 3.1% in 2012. Trend analysis showed that bovine tuberculosis had a seasonal variation and peaked mostly in July and August. The number of suggestive Tb lesion cases was highest in the month of August and lowest in the month of January, 2007-2012. This study shows that bovine tuberculosis is endemic in Plateau State. Trend analysis showed that bovine tuberculosis is seasonal and peaked mostly in July and August. Continuous surveillance through meat inspection is required to prevent zoonotic transmission of bovine tuberculosis.

Consumer Education for Today's Youth.

ERIC Educational Resources Information Center

Nickols, Sharon Y.; Powell, Claire L.

1979-01-01

A random survey of Oklahoma Four H Club members was made by Oklahoma State University to better understand the factors influencing adolescent consumer behavior. Based on this study, suggestions for improving extension consumer education through the Four H Clubs are made. (MF)

The Gender of Secondary School Principals.

ERIC Educational Resources Information Center

Bonuso, Carl; Shakeshaft, Charol

1983-01-01

A study was conducted to understand why so few of the secondary school principals in New York State are women. Results suggest two possible causes: either sufficient women candidates do not apply for the positions, or sex discrimination still exists. (KH)

Anticipatory processes under academic stress: an ERP study.

PubMed

Duan, Hongxia; Yuan, Yiran; Yang, Can; Zhang, Liang; Zhang, Kan; Wu, Jianhui

2015-03-01

It is well known that preparing for and taking high-stakes exams has a significant influence on the emotional and physiological wellbeing of exam-takers, but few studies have investigated the resulting cognitive changes. The current study examined the effect of examination-induced academic stress on anticipation in information processing. Anticipation was indexed using the contingent negative variation (CNV). Electroencephalograms (EEG) were collected from 42 participants using the classic S1-S2 paradigm. These participants were preparing for the Chinese National Postgraduate Entrance Exam (NPEE). EEGs were also collected from 21 age-matched, non-exam comparison participants. The levels of perceived stress and state anxiety were higher and both the initial CNV (iCNV) and the late CNV (lCNV) were more negative in the exam group than in the non-exam group. These results suggest that participants under academic stress experienced greater anticipation of upcoming events. More important, for the non-exam group, state anxiety was positively related to both the iCNV and lCNV amplitude, and this correlation existed when trait anxiety was controlled; however, there was no such relationship in the exam group. These results suggested that the cortical anticipatory activity in the high-stressed exam group reached the maximum ceiling, leaving little room for transient increases in state anxiety. Copyright © 2015 Elsevier Inc. All rights reserved.

Mood and anxiety regulation by nicotinic acetylcholine receptors: a potential pathway to modulate aggression and related behavioral states

PubMed Central

Picciotto, Marina R.; Lewis, Alan S.; van Schalkwyk, Gerrit I.; Mineur, Yann S.

2015-01-01

The co-morbidity between smoking and mood disorders is striking. Preclinical and clinical studies of nicotinic effects on mood, anxiety, aggression, and related behaviors, such as irritability and agitation, suggest that smokers may use the nicotine in tobacco products as an attempt to self-medicate symptoms of affective disorders. The role of nicotinic acetylcholine receptors (nAChRs) in circuits regulating mood and anxiety are beginning to be elucidated in animal models, but the mechanisms underlying the effects of nicotine on aggression-related behavioral states (ARBS) are still not understood. Clinical trials of nicotine or nicotinic medications for neurological and psychiatric disorders have often found effects of nicotinic medications on ARBS, but few trials have studied these outcomes systematically. Similarly, the increase in ARBS resulting from smoking cessation can be resolved by nicotinic agents, but the effects of nicotinic medications on these types of mental states and behaviors in non-smokers are less well understood. Here we review the literature on the role of nAChRs in regulating mood and anxiety, and subsequently on the closely related construct of ARBS. We suggest avenues for future study to identify how nAChRs and nicotinic agents may play a role in these clinically important areas. PMID:25582289

Trial-to-trial fluctuations in attentional state and their relation to intelligence.

PubMed

Unsworth, Nash; McMillan, Brittany D

2014-05-01

Trial-to-trial fluctuations in attentional state while performing measures of intelligence were examined in the current study. Participants performed various measures of fluid and crystallized intelligence while also providing attentional state ratings prior to each trial. It was found that pre-trial attentional state ratings strongly predicted subsequent trial performance on the fluid intelligence measures, such that when participants rated their current attentional state as highly focused on the current task, performance tended to be high compared to when participants reported their current attentional state as being low and unfocused on the current task. Furthermore, overall attentional state ratings and variability in attentional state ratings were moderately correlated with overall levels of performance on the fluid intelligence measures. However, attentional state ratings did not predict performance on the measure of crystallized intelligence. These results suggest a strong link between variation in attention state and variation in fluid intelligence as postulated by a number of recent theories. PsycINFO Database Record (c) 2014 APA, all rights reserved.

Understanding the transport properties of YNiBi half- Heusler alloy: An Ab-initio study

NASA Astrophysics Data System (ADS)

Sharma, Sonu; Kumar, Pradeep

2017-05-01

In the present work, we have studied the electronic and transport properties of YNiBi half-Heusler alloy by combining the first principles methods with the Boltzmann transport theory. The electronic band structure and total density of states plot suggest the presence of semiconducting ground state in the compound. The value of indirect band gap is found to be ˜0.21 eV. The origin of the band gap is associated primarily with the interaction between the Ni 3d and the Y 4d states. The room temperature value of Seebeck coefficient is ˜230 µVK-1. A moderate power factor of about 12×1014 μ Wcm-1 K-2 s-1 is obtained at 980 k.

Factors of Renewable Energy Deployment and Empirical Studies of United States Wind Energy

NASA Astrophysics Data System (ADS)

Can Sener, Serife Elif

Considered essential for countries' development, energy demand is growing worldwide. Unlike conventional sources, the use of renewable energy sources has multiple benefits, including increased energy security, sustainable economic growth, and pollution reduction, in particular greenhouse gas emissions. Nevertheless, there is a considerable difference in the share of renewable energy sources in national energy portfolios. This dissertation contains a series of studies to provide an outlook on the existing renewable energy deployment literature and empirically identify the factors of wind energy generation capacity and wind energy policy diffusion in the U.S. The dissertation begins with a systematic literature review to identify drivers and barriers which could help in understanding the diverging paths of renewable energy deployment for countries. In the analysis, economic, environmental, and social factors are found to be drivers, whereas political, regulatory, technical potential and technological factors are not classified as either a driver or a barrier (i.e., undetermined). Each main category contains several subcategories, among which only national income is found to have a positive impact, whereas all other subcategories are considered undetermined. No significant barriers to the deployment of renewable energy sources are found over the analyzed period. Wind energy deployment within the states related to environmental and economic factors was seldom discussed in the literature. The second study of the dissertation is thus focused on the wind energy deployment in the United States. Wind energy is among the most promising clean energy sources and the United States has led the world in per capita newly installed generation capacity since 2000. In the second study, using a fixed-effects panel data regression analysis, the significance of a number of economic and environmental factors are investigated for 39 states from 2000 to 2015. The results suggested that the increase in economic factors is related to a significant increase in the installed wind energy capacity, whereas, the increase in environmental factors is related to a significant decrease in the installed wind capacity. The final study explores the factors of diffusion of state- and local-level wind energy support policies which are considered fundamental factors of the continuum and development of wind power in the United States. To reveal the internal determinants of state's wind energy policy diffusion, we further narrow the scope and control for the geographical region in the final study. We limit our analysis to seven neighboring Midwestern states, which are located in the center of United States wind energy corridor. Using data from 2008 to 2015, the study investigates the significance of the following internal factors: wind power potential, per capita gross state product, unemployment rate, per capita value of the agriculture sector, number of establishments in agricultural sector, and state government control. Through the addition of interaction terms, the study also considers the behavioral differences in the explanatory variables under Republican and non-Republican state governance. Our findings suggest that the economic development potential and related environmental benefits were the common motivation for state- and local-level policy makers. Lastly, technical terms and agricultural sector presence provides additional motives for the state level diffusion of wind energy policies. The findings of this dissertation are expected to contribute to the understanding of how countries and states might best stimulate and support renewable energy, and in particular wind energy, deployment.

Pharmacological Modulation of Noradrenergic Arousal Circuitry Disrupts Functional Connectivity of the Locus Ceruleus in Humans

PubMed Central

Song, Andrew H.

2017-01-01

State-dependent activity of locus ceruleus (LC) neurons has long suggested a role for noradrenergic modulation of arousal. However, in vivo insights into noradrenergic arousal circuitry have been constrained by the fundamental inaccessibility of the human brain for invasive studies. Functional magnetic resonance imaging (fMRI) studies performed during site-specific pharmacological manipulations of arousal levels may be used to study brain arousal circuitry. Dexmedetomidine is an anesthetic that alters the level of arousal by selectively targeting α2 adrenergic receptors on LC neurons, resulting in reduced firing rate and norepinephrine release. Thus, we hypothesized that dexmedetomidine-induced altered arousal would manifest with reduced functional connectivity between the LC and key brain regions involved in the regulation of arousal. To test this hypothesis, we acquired resting-state fMRI data in right-handed healthy volunteers 18–36 years of age (n = 15, 6 males) at baseline, during dexmedetomidine-induced altered arousal, and recovery states. As previously reported, seed-based resting-state fMRI analyses revealed that the LC was functionally connected to a broad network of regions including the reticular formation, basal ganglia, thalamus, posterior cingulate cortex (PCC), precuneus, and cerebellum. Functional connectivity of the LC to only a subset of these regions (PCC, thalamus, and caudate nucleus) covaried with the level of arousal. Functional connectivity of the PCC to the ventral tegmental area/pontine reticular formation and thalamus, in addition to the LC, also covaried with the level of arousal. We propose a framework in which the LC, PCC, thalamus, and basal ganglia comprise a functional arousal circuitry. SIGNIFICANCE STATEMENT Electrophysiological studies of locus ceruleus (LC) neurons have long suggested a role for noradrenergic mechanisms in mediating arousal. However, the fundamental inaccessibility of the human brain for invasive studies has limited a precise understanding of putative brain regions that integrate with the LC to regulate arousal. Our results suggest that the PCC, thalamus, and basal ganglia are key components of a LC-noradrenergic arousal circuit. PMID:28626012

Flavor asymmetry of the nucleon sea and the five-quark components of the nucleons.

PubMed

Chang, Wen-Chen; Peng, Jen-Chieh

2011-06-24

The existence of the five-quark Fock states for the intrinsic charm quark in the nucleons was suggested some time ago, but conclusive evidence is still lacking. We generalize the previous theoretical approach to the light-quark sector and study possible experimental signatures for such five-quark states. In particular, we compare the d-ū and ū + d-s-s data with the calculations based on the five-quark Fock states. The qualitative agreement between the data and the calculations is interpreted as evidence for the existence of the intrinsic light-quark sea in the nucleons. The probabilities for the |uuduū and |uuddd Fock states are also extracted.

Origin of Broad Visible Emission from Branched Polysilane and Polygermane Chains

NASA Astrophysics Data System (ADS)

Watanabe, Akira; Sato, Takaaki; Matsuda, Minoru

2001-11-01

The emission properties of branched polysilane and polygermane are studied using time-resolved emission spectroscopy. As branched polymers, the organosilicon cluster (OSI) and organogermanium cluster (OGE) are investigated, which are prepared from tetrachlorosilane and tetrachlorogermane, respectively, and have a hyperbranched structure. The broad visible emissions of OSI and OGE are explained by the energy diagram based on a configuration coordinate model, and the excited states are attributed to a localized state around the branching point. The molecular orbital (MO) calculation suggested the formation of a localized state by the distortion around the branching point in the excited state. The potential barrier for the nonradiative relaxation process was determined from the temperature dependence of the emission lifetime.

Health insurance reform and HMO penetration in the small group market.

PubMed

Buchmueller, Thomas C; Liu, Su

This study uses data from several national employer surveys conducted between the late 1980s and the mid-1990s to investigate the effect of state-level underwriting reforms on HMO penetration in the small group health insurance market. We identify reform effects by exploiting cross-state variation in the timing and content of reform legislation and by using mid-sized and large employers, which were not affected by the legislation, as within-state control groups. While it is difficult to disentangle the effect of state reforms from other factors affecting HMO penetration in the small group markets, the results suggest a positive relationship between insurance market regulations and HMO penetration.

Ab Initio Calculations of Singlet and Triplet Excited States of Chlorine Nitrate and Nitric Acid

NASA Technical Reports Server (NTRS)

Grana, Ana M.; Lee, Timothy J.; Head-Gordon, Martin; Langhoff, Stephen R. (Technical Monitor)

1994-01-01

Ab initio calculations of vertical excitations to singlet and triplet excited states of chlorine nitrate and nitric acid are reported. The nature of the electronic transitions are examined by decomposing the difference density into the sum of detachment and attachment densities. Counterparts for the three lowest singlet excited states of nitric acid survive relatively unperturbed in chlorine nitrate, while other low-lying singlet states of chlorine nitrate appear to be directly dissociative in the ClO chromophore. These results suggest an assignment of the two main peaks in the experimental chlorine nitrate absorption spectrum. In addition, triplet vertical excitations and the lowest optimized triplet geometries of both molecules are studied.

Mothers' use of cognitive state verbs in picture-book reading and the development of children's understanding of mind: a longitudinal study.

PubMed

Adrián, Juan E; Clemente, Rosa Ana; Villanueva, Lidón

2007-01-01

Mothers read stories to their children (N=41) aged between 3.3 years and 5.11 years old, and children then completed two false-belief tasks. One year later, mothers read a story to 37 of those children who were also given four tasks to assess their advanced understanding of mental states. Mothers' early use of cognitive verbs in picture-book reading correlated with their children's later understanding of mental states. Some pragmatic aspects of maternal input correlated with children's later outcomes. Two different factors in mothers' cognitive discourse were identified, suggesting a zone of proximal development in children's understanding of mental states.

Imaging Mitochondrial Redox Potential and Its Possible Link to Tumor Metastatic Potential

PubMed Central

Li, Lin Z.

2012-01-01

Cellular redox states can regulate cell metabolism, growth, differentiation, motility, apoptosis, signaling pathways, and gene expressions etc. Growing body of literature suggest importance of redox status for cancer progression. While most studies on redox state were done on cells and tissue lysates, it is important to understand the role of redox state in tissue in vivo/ex vivo and image its heterogeneity. Redox scanning is a clinically-translatable method for imaging tissue mitochondrial redox potential with a submillimeter resolution. Redox scanning data in mouse models of human cancers demonstrate a correlation between mitochondrial redox state and tumor metastatic potential. I will discuss the significance of this correlation and possible directions for future research. PMID:22895837

Investigation into chromophore excited-state coupling in allophycocyanin

NASA Astrophysics Data System (ADS)

Zheng, Xiguang; Zhao, Fuli; Wang, He Z.; Gao, Zhaolan; Yu, Zhenxin; Zhu, Jinchang; Xia, Andong; Jiang, Lijin

1994-08-01

Both theoretical and experimental studies are presented on chromophore excited-state coupling in linker-free allophycocyanin (APC), one of the antenna phycobiliproteins in algal photosynthesis. A three-site-coupling model has been introduced to describe the exciton interaction mechanism amoung the excited (beta) chromophore in APC, and the exciton energy splitting is estimated. Picosecond polarized fluorescence experiments both on monomeric and trimeric APC isolated from alga Spirulina platensis have been performed. The experimental results show that APC monomer and trimer exhibit remarkedly different spectropic characteristics, and satisfy the suggestion of strong excited- state coupling among chromophores in APC.

Continuous distribution of emission states from single CdSe/ZnS quantum dots.

PubMed

Zhang, Kai; Chang, Hauyee; Fu, Aihua; Alivisatos, A Paul; Yang, Haw

2006-04-01

The photoluminescence dynamics of colloidal CdSe/ZnS/streptavidin quantum dots were studied using time-resolved single-molecule spectroscopy. Statistical tests of the photon-counting data suggested that the simple "on/off" discrete state model is inconsistent with experimental results. Instead, a continuous emission state distribution model was found to be more appropriate. Autocorrelation analysis of lifetime and intensity fluctuations showed a nonlinear correlation between them. These results were consistent with the model that charged quantum dots were also emissive, and that time-dependent charge migration gave rise to the observed photoluminescence dynamics.

Embodied free will beliefs: some effects of physical states on metaphysical opinions.

PubMed

Ent, Michael R; Baumeister, Roy F

2014-07-01

The present research suggests that people's bodily states affect their beliefs about free will. People with epilepsy and people with panic disorder, which are disorders characterized by a lack of control over one's body, reported less belief in free will compared to people without such disorders (Study 1). The more intensely people felt sexual desire, physical tiredness, and the urge to urinate, the less they believed in free will (Study 2). Among non-dieters, the more intensely they felt hunger, the less they believed in free will. However, dieters showed a trend in the opposite direction (Study 3). Copyright © 2014 Elsevier Inc. All rights reserved.

Middle School Foreign Language Instruction: A Missed Opportunity?

ERIC Educational Resources Information Center

Kissau, Scott; Adams, Mary Jo; Algozzine, Bob

2015-01-01

Multiple studies conducted over the past decade have suggested the motivational and proficiency-related benefits of commencing language instruction at an early age. Limitations in many of these studies, however, have prevented their results from being applied to the teaching of foreign languages in the United States. In response to calls for…

Social Studies Grade 3: Teaching Systems I.

ERIC Educational Resources Information Center

New York State Education Dept., Albany. Bureau of Elementary Curriculum Development.

This publication has been prepared by the Curriculum Development Center (The University of the State of New York) in response to many requests from teachers for help in implementing the new social studies. Suggestions are given for the teaching materials which are available for use in such teaching. The nature of the relationship between man and…

Recreation in the United States. National Historic Landmark Theme Study.

ERIC Educational Resources Information Center

Charleton, James H.

This report examines a number of outstanding and illustrative examples of a broad range of properties representing recreational activities that suggest themselves for possible National Historic Landmark recognition. The properties described in the study have been selected to represent places and activities that have had a major impact on American…

Differences in brain functional connectivity at resting state in neonates born to healthy obese or normal-weight mothers

USDA-ARS?s Scientific Manuscript database

Recent studies have shown associations between maternal obesity at pre- or early pregnancy and long-term neurodevelopment in children, suggesting in utero effects of maternal obesity on offspring brain development. In this study, we examined whether brain functional connectivity to the prefrontal lo...

The Energy Problem and Social Education: Some Opportunities, Quandaries, and Goals.

ERIC Educational Resources Information Center

Allen, Rodney F.

This paper examines the need for energy education, discusses classroom opportunities and quandaries for teaching about energy, and provides some suggestions for social studies educators. Two recent studies show that there is a real need for energy education. First, the Education Commission of the United States surveyed the energy knowledge and…

Using Online Learning To Meet Workforce Demand: A Case Study of Stakeholder Influence.

ERIC Educational Resources Information Center

Benson, Angela D.

2002-01-01

Investigated how stakeholder interests influenced one state's efforts to provide online undergraduate degree programs to meet workforce needs. Describes the use of an embedded qualitative case study design; discusses findings that showed that the interests of some stakeholder groups prevailed at the expense of other groups; and suggests further…

Reappraisal of Social Network Research in Educational Contexts.

ERIC Educational Resources Information Center

Scherer, Jacqueline

Three network studies in education are reviewed in order to assess the current "state of the art." New directions for developing social network analysis (SNA) in education, based upon experiences from a study of school-community relations in Pontiac, Michigan, are suggested. One concern for the future of SNA stems from the elevation of…

Conifer root proliferation after 20 years of soil compaction

Treesearch

Matt D. Busse; Gary O. Fiddler; Carol J. Shestak

2017-01-01

Soil compaction is known to limit plant growth by reducing soil macroporosity and restricting gas, water, and root movement. Recent evidence from study sites across the United States and Canada, however, suggests that tree growth is not universally affected by soil compaction from forest harvesting practices. Our observational study examined rooting patterns in mixed...

Lifestyle Correlates of Musical Preference: 3. Travel, Money, Education, Employment and Health

ERIC Educational Resources Information Center

North, Adrian C.; Hargreaves, David J.

2007-01-01

Several studies indicate that musical preferences provide a means of discriminating between social groups, and suggest indirectly that musical preferences should correlate with a variety of different lifestyle choices. In this study, 2532 participants responded to a questionnaire asking them to state their musical preference and also to provide…

The association of circadian clock candidate genes to increased adiposity in the TIGER study

USDA-ARS?s Scientific Manuscript database

Obesity is a highly prevalent disease that has become a major health crisis in the United States. A number of studies have suggested a link between the altered sleep/wake patterns associated with our "24 hour" lifestyle and obesity. We hypothesize that disruption of the circadian clock intrinsic t...

Perceptions of Co-Teaching in the Clinical Experience: How Well Is It Working?

ERIC Educational Resources Information Center

Kinne, Lenore J.; Ryan, Carol; Faulkner, Shawn A.

2016-01-01

This study examined the perceptions of teacher candidates, cooperating teachers, and university supervisors in the first year of state-mandated co-teaching in the clinical experience. Study results suggest the need (a) to emphasize the importance of the teacher candidate exerting leadership, (b) to develop and communicate specific criteria for…

Opportunities and methodological challenges in EEG and MEG resting state functional brain network research.

PubMed

van Diessen, E; Numan, T; van Dellen, E; van der Kooi, A W; Boersma, M; Hofman, D; van Lutterveld, R; van Dijk, B W; van Straaten, E C W; Hillebrand, A; Stam, C J

2015-08-01

Electroencephalogram (EEG) and magnetoencephalogram (MEG) recordings during resting state are increasingly used to study functional connectivity and network topology. Moreover, the number of different analysis approaches is expanding along with the rising interest in this research area. The comparison between studies can therefore be challenging and discussion is needed to underscore methodological opportunities and pitfalls in functional connectivity and network studies. In this overview we discuss methodological considerations throughout the analysis pipeline of recording and analyzing resting state EEG and MEG data, with a focus on functional connectivity and network analysis. We summarize current common practices with their advantages and disadvantages; provide practical tips, and suggestions for future research. Finally, we discuss how methodological choices in resting state research can affect the construction of functional networks. When taking advantage of current best practices and avoid the most obvious pitfalls, functional connectivity and network studies can be improved and enable a more accurate interpretation and comparison between studies. Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Intrinsic Brain Activity in Altered States of Consciousness

PubMed Central

Boly, M.; Phillips, C.; Tshibanda, L.; Vanhaudenhuyse, A.; Schabus, M.; Dang-Vu, T.T.; Moonen, G.; Hustinx, R.; Maquet, P.; Laureys, S.

2010-01-01

Spontaneous brain activity has recently received increasing interest in the neuroimaging community. However, the value of resting-state studies to a better understanding of brain–behavior relationships has been challenged. That altered states of consciousness are a privileged way to study the relationships between spontaneous brain activity and behavior is proposed, and common resting-state brain activity features observed in various states of altered consciousness are reviewed. Early positron emission tomography studies showed that states of extremely low or high brain activity are often associated with unconsciousness. However, this relationship is not absolute, and the precise link between global brain metabolism and awareness remains yet difficult to assert. In contrast, voxel-based analyses identified a systematic impairment of associative frontoparieto–cingulate areas in altered states of consciousness, such as sleep, anesthesia, coma, vegetative state, epileptic loss of consciousness, and somnambulism. In parallel, recent functional magnetic resonance imaging studies have identified structured patterns of slow neuronal oscillations in the resting human brain. Similar coherent blood oxygen level–dependent (BOLD) systemwide patterns can also be found, in particular in the default-mode network, in several states of unconsciousness, such as coma, anesthesia, and slow-wave sleep. The latter results suggest that slow coherent spontaneous BOLD fluctuations cannot be exclusively a reflection of conscious mental activity, but may reflect default brain connectivity shaping brain areas of most likely interactions in a way that transcends levels of consciousness, and whose functional significance remains largely in the dark. PMID:18591474

Electrostatic effects in unfolded staphylococcal nuclease

PubMed Central

Fitzkee, Nicholas C.; García-Moreno E, Bertrand

2008-01-01

Structure-based calculations of pK a values and electrostatic free energies of proteins assume that electrostatic effects in the unfolded state are negligible. In light of experimental evidence showing that this assumption is invalid for many proteins, and with increasing awareness that the unfolded state is more structured and compact than previously thought, a detailed examination of electrostatic effects in unfolded proteins is warranted. Here we address this issue with structure-based calculations of electrostatic interactions in unfolded staphylococcal nuclease. The approach involves the generation of ensembles of structures representing the unfolded state, and calculation of Coulomb energies to Boltzmann weight the unfolded state ensembles. Four different structural models of the unfolded state were tested. Experimental proton binding data measured with a variant of nuclease that is unfolded under native conditions were used to establish the validity of the calculations. These calculations suggest that weak Coulomb interactions are an unavoidable property of unfolded proteins. At neutral pH, the interactions are too weak to organize the unfolded state; however, at extreme pH values, where the protein has a significant net charge, the combined action of a large number of weak repulsive interactions can lead to the expansion of the unfolded state. The calculated pK a values of ionizable groups in the unfolded state are similar but not identical to the values in small peptides in water. These studies suggest that the accuracy of structure-based calculations of electrostatic contributions to stability cannot be improved unless electrostatic effects in the unfolded state are calculated explicitly. PMID:18227429

Analysis of the methylation patterns of the p16 INK4A, p15 INK4B, and APC genes in gastric adenocarcinoma patients from a Brazilian population.

PubMed

do Nascimento Borges, Bárbara; Burbano, Rommel Mario Rodriguez; Harada, Maria Lúcia

2013-08-01

Gastric cancer is a major public health problem in Pará state, where studies suggest complex genetic and epigenetic profiles of the population, indicating the need for the identification of molecular markers for this tumor type. In the present study, the methylation patterns of three genes [p16 (INK4A), p15 (INK4B), and adenomatous polyposis coli (APC)] were assessed in patients with gastric adenocarcinoma from Pará state in order to identify possible molecular markers of gastric carcinogenesis. DNA samples from tumoral and non-tumoral gastric tissues were modified with sodium bisulfite. A fragment of the promoter region of each gene was amplified and sequenced, and samples with more than 20 % of methylated CpG sites were considered hypermethylated. The correlation between the methylation pattern of the selected genes and the MTHFR C677T polymorphism, as well as the relationship between APC and CDH1 methylation, were evaluated. The results suggest that APC hypermethylation is an age-specific marker of gastric carcinogenesis, and the concordance of this event with CDH1 hypermethylation suggests that the Wnt pathway has an important role in gastric carcinogenesis. While the hypermethylation pattern of p15 (INK4B) seems to be an earlier event in this type of tumor, the hypomethylated status of this gene seems to be correlated to the C677T MTHFR TT genotype. On the other hand, the observed pattern of p16 (INK4A) hypermethylation suggests that this event is a good marker for the gastric cancer pathway in the Pará state population.

Why farmers adopt best management practice in the United States: A meta-analysis of the adoption literature

USGS Publications Warehouse

Baumgart-Getz, Adam; Stalker Prokopy, Linda; Floress, Kristin

2012-01-01

This meta-analysis of both published and unpublished studies assesses factors believed to influence adoption of agricultural Best Management Practices in the United States. Using an established statistical technique to summarize the adoption literature in the United States, we identified the following variables as having the largest impact on adoption: access to and quality of information, financial capacity, and being connected to agency or local networks of farmers or watershed groups. This study shows that various approaches to data collection affect the results and comparability of adoption studies. In particular, environmental awareness and farmer attitudes have been inconsistently used and measured across the literature. This meta-analysis concludes with suggestions regarding the future direction of adoption studies, along with guidelines for how data should be presented to enhance the adoption of conservation practices and guide research.

A quantitative analysis of the state of knowledge of turtles of the United States and Canada

USGS Publications Warehouse

Lovich, Jeffrey E.; Ennen, Joshua R.

2013-01-01

The “information age” ushered in an explosion of knowledge and access to knowledge that continues to revolutionize society. Knowledge about turtles, as measured by number of published papers, has been growing at an exponential rate since the early 1970s, a phenomenon mirrored in all scientific disciplines. Although knowledge about turtles, as measured by number of citations for papers in scientific journals, has been growing rapidly, this taxonomic group remains highly imperiled suggesting that knowledge is not always successfully translated into effective conservation of turtles. We reviewed the body of literature on turtles of the United States and Canada and found that: 1) the number of citations is biased toward large-bodied species, 2) the number of citations is biased toward wide-ranging species, and 3) conservation status has little effect on the accumulation of knowledge for a species, especially after removing the effects of body size or range size. The dispersion of knowledge, measured by Shannon Weiner diversity and evenness indices across species, was identical from 1994 to 2009 suggesting that poorly studied species remained poorly-studied species while well-studied species remained well studied. Several species listed as threatened or endangered under the U.S. Endangered Species Act (e.g., Pseudemys alabamensis, Sternotherus depressus, and Graptemys oculifera) remain poorly studied with the estimated number of citations for each ranging from only 13-24. The low number of citations for these species could best be explained by their restricted distribution and/or their smaller size. Despite the exponential increase in knowledge of turtles in the United States and Canada, no species of turtle listed under the Endangered Species Act has ever been delisted for reason of recovery. Therefore, increased knowledge does not necessarily contribute appreciably to recovery of threatened turtles.

Edge-on and face-on functionalized Pc on enriched semiconducting SWCNT hybrids.

PubMed

Arellano, Luis M; Martín-Gomis, Luis; Gobeze, Habtom B; Molina, Desiré; Hermosa, Cristina; Gómez-Escalonilla, María J; Fierro, José Luis G; Sastre-Santos, Ángela; D'Souza, Francis; Langa, Fernando

2018-03-15

Enriched semiconducting single-walled carbon nanotubes (SWCNT (6,5) and SWCNT (7,6)) and HiPco nanotubes were covalently functionalized with either zinc phthalocyanine or silicon phthalocyanine as electron donors. The synthetic strategy resulted in edge-on and face-on geometries with respect to the phthalocyanine geometry, with both phthalocyanines held by an electronically conducting diphenylacetylene linker. The extent of functionalization in the MPc-SWCNT (M = Zn or Si) donor-acceptor nanohybrids was determined by systematic studies involving AFM, TGA, XPS, optical and Raman techniques. Intramolecular interactions in MPc-SWCNT nanohybrids were probed by studies involving optical absorbance, Raman, luminescence and electrochemical studies. Different degrees of interactions were observed depending on the type of MPc and mode of attachment. Substantial quenching of MPc fluorescence in these hybrids was observed from steady-state and three-dimensional fluorescence mapping, which suggests the occurrence of excited state events. Evidence for the occurrence of excited state charge transfer type interactions was subsequently secured from femtosecond transient absorption studies covering both the visible and near-infrared regions. Furthermore, electron-pooling experiments performed in the presence of a sacrificial electron donor and a second electron acceptor revealed accumulation of one-electron reduced product upon continuous irradiation of the nanohybrids. In such experiments, the ZnPc-SWCNT (6,5) nanohybrid outperformed other nanohybrids and this suggests that this is a superior donor-acceptor system for photocatalytic applications.

Medical Marijuana Laws May Be Associated With A Decline In The Number Of Prescriptions For Medicaid Enrollees.

PubMed

Bradford, Ashley C; Bradford, W David

2017-05-01

In the past twenty years, twenty-eight states and the District of Columbia have passed some form of medical marijuana law. Using quarterly data on all fee-for-service Medicaid prescriptions in the period 2007-14, we tested the association between those laws and the average number of prescriptions filled by Medicaid beneficiaries. We found that the use of prescription drugs in fee-for-service Medicaid was lower in states with medical marijuana laws than in states without such laws in five of the nine broad clinical areas we studied. If all states had had a medical marijuana law in 2014, we estimated that total savings for fee-for-service Medicaid could have been $1.01 billion. These results are similar to those in a previous study we conducted, regarding the effects of medical marijuana laws on the number of prescriptions within the Medicare population. Together, the studies suggest that in states with such laws, Medicaid and Medicare beneficiaries will fill fewer prescriptions. Project HOPE—The People-to-People Health Foundation, Inc.

A systematic review of yoga for state anxiety: considerations for occupational therapy.

PubMed

Chugh-Gupta, Neha; Baldassarre, Fulvia G; Vrkljan, Brenda H

2013-06-01

State anxiety can result from a variety of life situations. This type of anxiety can disrupt occupational engagement and performance, thereby affecting rehabilitation and recovery. Occupational therapists need to address the connection between mind-body-spirit and its relationship to performance and engagement in meaningful occupations. Yoga, when used as an adjunct to therapy, has the potential to address state anxiety. The aim was to systematically review the evidence concerning the effectiveness of yoga as a treatment approach for state anxiety. Six electronic databases, the authors' own files, and the references of included studies from 1990 to July 2011 were searched. A total of 25 unique studies represented by 26 publications made up the sample: two systematic reviews; 16 randomized controlled trials, and seven prospective, controlled, non-randomized studies. Evidence suggests yoga can be a viable therapeutic option for reducing state anxiety in certain situations. In making the determination to recommend yoga as an intervention, occupational therapists should consider the client's circumstances and values as well as the type and intensity of the yoga program.

The impact of school suspension on student tobacco use: A longitudinal study in Victoria, Australia and Washington State, United States

PubMed Central

Hemphill, Sheryl A.; Heerde, Jessica A.; Herrenkohl, Todd I.; Toumbourou, John W.; Catalano, Richard F.

2011-01-01

Context School suspension may have unintended consequences in contributing to problem behaviors including school drop-out, substance use, and antisocial behavior. Tobacco use is an early-onset problem behavior, but prospective studies of the effects of suspension on tobacco use are lacking. Method Longitudinal school-based survey of students drawn as a 2-stage cluster sample, administered in 2002 and 2003 in Washington State, United States and Victoria, Australia. The study uses statewide representative samples of students in Grades 7 and 9 (N = 3,599). Results Rates of tobacco use were higher for Victorian than Washington State students. School suspension remained a predictor of current tobacco use at 12-month follow-up, after controlling for established risk factors including prior tobacco and other drug use for Grade 7 but not Grade 9 students. Conclusions School suspension is associated with tobacco use in early adolescence, itself an established predictor of adverse outcomes in young people. Findings suggest the need to explore process mechanisms and alternatives to school suspensions as a response to challenging student behavior in early adolescence. PMID:21586667

Hazardous air pollutants and primary liver cancer in Texas.

PubMed

Cicalese, Luca; Curcuru, Giuseppe; Montalbano, Mauro; Shirafkan, Ali; Georgiadis, Jeremias; Rastellini, Cristiana

2017-01-01

The incidence of hepatocellular carcinoma (HCC), the most common primary liver cancer, is increasing in the US and tripled during the past two decades. The reasons for such phenomenon remain poorly understood. Texas is among continental states with the highest incidence of liver cancer with an annual increment of 5.7%. Established risk factors for HCC include Hepatitis B and C (HBV, HCV) viral infection, alcohol, tobacco and suspected risk factors include obesity and diabetes. While distribution of these risk factors in the state of Texas is similar to the national data and homogeneous, the incidence of HCC in this state is exceptionally higher than the national average and appears to be dishomogeneous in various areas of the state suggesting that other non-recognized risk factors might play a role. No population-based studies are currently available investigating the effect of exposure to Hazardous Air Pollutants (HAPs) as a contributing risk factor for liver cancer. Incidence rate of liver cancer in Texas by counties for the time period between 2002 and 2012 was obtained from the Texas Cancer Registry (TCR). Through Principal Component Analysis (PCA) a subgroup of pollutants, explaining almost all the dataset variability, were identified and used to cluster Texas counties. The analysis generated 4 clusters showing liver cancer rate either higher or lower than national average in association with either high or low levels of HAPs emission in the environment. The study shows that the selected relevant HAPs, 10 among 253 analyzed, produce a significant correlation (P = 0.01-0.05) and some of these have been previously identified as carcinogens. An association between the increased production and consequent exposure to these HAPs and a higher presence of liver cancer in certain counties is suggested. This study provides a new insight on this complex multifactorial disease suggesting that environmental substances might play a role in the etiology of this cancer.

Mandatory overtime regulations and nurse overtime.

PubMed

Bae, Sung-Heui; Brewer, Carol

2010-05-01

A descriptive study used data from the 2004 National Sample Survey of Registered Nurses to examine the nature and occurrence of RN mandatory, voluntary overtime, paid on-call, and total work hours and their association with mandatory overtime regulations in United States. About half of the nurses worked more than 40 hrs per week. Nurses working in states regulating mandatory overtime reported lower levels of mandatory overtime hours than states without regulations or states restricting total work hours. The percent of RNs working 61 hrs and over per week in states without regulations was lower than that in states with regulations. Nurses working in nursing homes reported higher levels of the percentage of mandatory overtime hours worked than those working in hospitals. This suggested that governments need to continuously supervise healthcare institutions, including both hospitals and nursing homes, to ensure adherence to mandatory overtime regulations.

The work-family interface in the United States and Singapore: conflict across cultures.

PubMed

Galovan, Adam M; Fackrell, Tamara; Buswell, Lydia; Jones, Blake L; Hill, E Jeffrey; Carroll, Sarah June

2010-10-01

This article examines the work-family interface in a cross-cultural comparison between two nationally representative samples from the United States (n = 1,860) and Singapore (n = 1,035) with emphasis on work-family conflict. Family-to-work conflict was negatively related to marital satisfaction in both Singapore and the United States, although the effect was stronger in the United States. Similarly, family-to-work conflict was positively related to job satisfaction in the United States but was negatively related in Singapore. As expected, schedule flexibility was negatively related to depression in the United States, but in Singapore the relationship was positive. These findings suggest that theoretical relationships in the work-family interface developed in the more culturally individualistic West may need to be adapted when studying populations in the more collectivist East.

Wavelet entropy characterization of elevated intracranial pressure.

PubMed

Xu, Peng; Scalzo, Fabien; Bergsneider, Marvin; Vespa, Paul; Chad, Miller; Hu, Xiao

2008-01-01

Intracranial Hypertension (ICH) often occurs for those patients with traumatic brain injury (TBI), stroke, tumor, etc. Pathology of ICH is still controversial. In this work, we used wavelet entropy and relative wavelet entropy to study the difference existed between normal and hypertension states of ICP for the first time. The wavelet entropy revealed the similar findings as the approximation entropy that entropy during ICH state is smaller than that in normal state. Moreover, with wavelet entropy, we can see that ICH state has the more focused energy in the low wavelet frequency band (0-3.1 Hz) than the normal state. The relative wavelet entropy shows that the energy distribution in the wavelet bands between these two states is actually different. Based on these results, we suggest that ICH may be formed by the re-allocation of oscillation energy within brain.

Compensation for injured study subjects in clinical trials: an ethical obligation in human subjects research.

PubMed

Buechner, Bianca

2012-01-01

The Presidential Commission for the Study of Bioethical Issues suggested in its report "Research Across Borders: Proceedings of the International Research Panel of the Presidential Commission for the Study of Bioethical Issues" that the United States should implement a system to compensate research subjects for research-related injuries. This article not only analyzes the Commission's recommendation critically, but also discusses if an ethical obligation exists to compensate study subjects for research-related injuries. In addition, the article compares the status quo of the United States to the one in Germany. Germany is one of the countries, which has an established insurance system for research-related injuries based on a non-fault system.

X-ray diffraction study of laser-driven solid-state diffusional mixing and new phase formation in Ni-Pt multilayers [X-ray diffraction study of laser-driven solid-state diffusional mixing and new phase formation

DOE PAGES

Kelly, B. G.; Loether, A.; Unruh, K. M.; ...

2017-02-01

An in situ optical pump and x-ray probe technique has been utilized to study photoinitiated solid-state diffusion in a Ni-Pt multilayer system. Hard x-ray diffraction has been used to follow the systematic growth of the NiPt alloy as a function of laser intensity and total energy deposited. It is observed that new phase growth can be driven in as little as one laser pulse, and that repeated photoexcitation can completely convert the entire multilayer structure into a single metallic alloy. In conclusion, the data suggest that lattice strain relaxation takes place prior to atomic diffusion and the formation of amore » NiPt alloy.« less

X-ray diffraction study of laser-driven solid-state diffusional mixing and new phase formation in Ni-Pt multilayers [X-ray diffraction study of laser-driven solid-state diffusional mixing and new phase formation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kelly, B. G.; Loether, A.; Unruh, K. M.

An in situ optical pump and x-ray probe technique has been utilized to study photoinitiated solid-state diffusion in a Ni-Pt multilayer system. Hard x-ray diffraction has been used to follow the systematic growth of the NiPt alloy as a function of laser intensity and total energy deposited. It is observed that new phase growth can be driven in as little as one laser pulse, and that repeated photoexcitation can completely convert the entire multilayer structure into a single metallic alloy. In conclusion, the data suggest that lattice strain relaxation takes place prior to atomic diffusion and the formation of amore » NiPt alloy.« less

Consciousness and the Invention of Morel

PubMed Central

Perogamvros, Lampros

2013-01-01

A scientific study of consciousness should take into consideration both objective and subjective measures of conscious experiences. To this date, very few studies have tried to integrate third-person data, or data about the neurophysiological correlates of conscious states, with first-person data, or data about subjective experience. Inspired by Morel's invention (Casares, 1940), a literary machine capable of reproducing sensory-dependent external reality, this article suggests that combination of virtual reality techniques and brain reading technologies, that is, decoding of conscious states by brain activity alone, can offer this integration. It is also proposed that the multimodal, simulating, and integrative capacities of the dreaming brain render it an “endogenous” Morel's machine, which can potentially be used in studying consciousness, but not always in a reliable way. Both the literary machine and dreaming could contribute to a better understanding of conscious states. PMID:23467765

Caffeine reduces resting-state BOLD functional connectivity in the motor cortex.

PubMed

Rack-Gomer, Anna Leigh; Liau, Joy; Liu, Thomas T

2009-05-15

In resting-state functional magnetic resonance imaging (fMRI), correlations between spontaneous low-frequency fluctuations in the blood oxygenation level dependent (BOLD) signal are used to assess functional connectivity between different brain regions. Changes in resting-state BOLD connectivity measures are typically interpreted as changes in coherent neural activity across spatially distinct brain regions. However, this interpretation can be complicated by the complex dependence of the BOLD signal on both neural and vascular factors. For example, prior studies have shown that vasoactive agents that alter baseline cerebral blood flow, such as caffeine and carbon dioxide, can significantly alter the amplitude and dynamics of the task-related BOLD response. In this study, we examined the effect of caffeine (200 mg dose) on resting-state BOLD connectivity in the motor cortex across a sample of healthy young subjects (N=9). We found that caffeine significantly (p<0.05) reduced measures of resting-state BOLD connectivity in the motor cortex. Baseline cerebral blood flow and spectral energy in the low-frequency BOLD fluctuations were also significantly decreased by caffeine. These results suggest that caffeine usage should be carefully considered in the design and interpretation of resting-state BOLD fMRI studies.

The future of financing for long-term care: the Own Your Future campaign.

PubMed

Iwasaki, Michiko; McCurry, Susan M; Borson, Soo; Jones, James A

2010-10-01

The purpose of this study was to examine the outreach effort and impact of a joint federal-state campaign, Own Your Future, promoting awareness and planning for long-term care (LTC) in the state of Washington. The study applied survey methodology to evaluate the extent of campaign dissemination, evidence of its impact on LTC planning behaviors, and barriers to purchasing private LTC insurance. A total of 3,198 survey responses from a randomly selected community sample and a Washington State employee sample (ages 51 to 71) were analyzed. Results indicated that the impact of the campaign was limited, both with respect to awareness of the campaign itself and to initiation of LTC planning behaviors. Quantitative data revealed a high prevalence of health-related problems (e.g., obesity, diabetes), inadequate knowledge of basic LTC-related information (e.g., cost, payers), and negative attitudes toward purchasing LTC insurance among respondents. Qualitative analyses suggested that respondents perceived significant problems related to affordability and accountability within the current LTC insurance industry. These possible barriers to the purchase of LTC insurance suggest targets to be addressed by policy makers seeking to find ways to offset the public costs of LTC.

A High-Density EEG Investigation into Steady State Binaural Beat Stimulation

PubMed Central

Goodin, Peter; Ciorciari, Joseph; Baker, Kate; Carrey, Anne-Marie; Harper, Michelle; Kaufman, Jordy

2012-01-01

Binaural beats are an auditory phenomenon that has been suggested to alter physiological and cognitive processes including vigilance and brainwave entrainment. Some personality traits measured by the NEO Five Factor Model have been found to alter entrainment using pulsing light stimuli, but as yet no studies have examined if this occurs using steady state presentation of binaural beats for a relatively short presentation of two minutes. This study aimed to examine if binaural beat stimulation altered vigilance or cortical frequencies and if personality traits were involved. Thirty-one participants were played binaural beat stimuli designed to elicit a response at either the Theta (7 Hz) or Beta (16 Hz) frequency bands while undertaking a zero-back vigilance task. EEG was recorded from a high-density electrode cap. No significant differences were found in vigilance or cortical frequency power during binaural beat stimulation compared to a white noise control period. Furthermore, no significant relationships were detected between the above and the Big Five personality traits. This suggests a short presentation of steady state binaural beats are not sufficient to alter vigilance or entrain cortical frequencies at the two bands examined and that certain personality traits were not more susceptible than others. PMID:22496862

A high-density EEG investigation into steady state binaural beat stimulation.

PubMed

Goodin, Peter; Ciorciari, Joseph; Baker, Kate; Carey, Anne-Marie; Carrey, Anne-Marie; Harper, Michelle; Kaufman, Jordy

2012-01-01

Binaural beats are an auditory phenomenon that has been suggested to alter physiological and cognitive processes including vigilance and brainwave entrainment. Some personality traits measured by the NEO Five Factor Model have been found to alter entrainment using pulsing light stimuli, but as yet no studies have examined if this occurs using steady state presentation of binaural beats for a relatively short presentation of two minutes. This study aimed to examine if binaural beat stimulation altered vigilance or cortical frequencies and if personality traits were involved. Thirty-one participants were played binaural beat stimuli designed to elicit a response at either the Theta (7 Hz) or Beta (16 Hz) frequency bands while undertaking a zero-back vigilance task. EEG was recorded from a high-density electrode cap. No significant differences were found in vigilance or cortical frequency power during binaural beat stimulation compared to a white noise control period. Furthermore, no significant relationships were detected between the above and the Big Five personality traits. This suggests a short presentation of steady state binaural beats are not sufficient to alter vigilance or entrain cortical frequencies at the two bands examined and that certain personality traits were not more susceptible than others.

A review of the present state and future policy alternatives for home visit nursing services in Korea.

PubMed

Lim, Ji Young; Noh, Wonjung; Kim, Eunjoo; Choi, Kyung Won

2014-01-01

The aim of this study was to describe the current state of home visit nursing services in the Korean context and to suggest future policy directions. First, the three home visit nursing services that have developed in Korea are compared using the analytic framework provided by Gilbert and Terrell in 2012. The framework is based on four dimensions of social welfare: users, services, source of funds, and service delivery process. Second, we perform a strength, weakness, opportunity, and threat analysis to suggest comprehensive and constructive home visit nursing service policies for the future. Specifically, we advocate the creation of an organization that steers the central government to operate an integrated management organization to distribute services and reduce redundancy for preventing the waste of both medical and state financial resources. This study also recommends the development of educational programs to improve the quality of services and service evaluation criteria for the objective assessment of those services. These policy guidelines may prove useful both for Korea and for other countries that intend to prepare or revise their home visit nursing service systems. © 2014 Wiley Periodicals, Inc.

Considering a Merger?

ERIC Educational Resources Information Center

Thompson, Hugh L.

1985-01-01

A successful college merger is often conditioned by geography, previous cooperation, complementary instructional programs, academic excellence, and common political interest. Suggestions when considering a merger are offered. A case study of a failed merger between Detroit Institute of Technology and Wayne State University is presented. (MLW)

Science/Society Case Study. Solid Wastes: Diamonds in the Rough?

ERIC Educational Resources Information Center

Moore, John W., Ed.; Moore, Elizabeth A., Ed.

1976-01-01

Expounds on the current solid waste disposal problems of the United States and current methods of waste disposal. Includes a description of the use of solid waste in power generating plants. A bibliography of suggested readings is provided. (CP)

Intensive Teacher Training in Math Fails to Lift Exam Scores, Study Says

ERIC Educational Resources Information Center

Viadero, Debra

2010-01-01

The author reports findings from a federal study of 77 middle schools which suggest that even intensive, state-of-the-art efforts to boost teachers' skills on the job may not lead to significant gains in student achievement right away. The "Middle School Mathematics Professional Development Impact Study," which was released in April, is the second…

Religious Conversion to Islam and Its Influence on Workplace Relationships in American and Egyptian Schools: A Case Study

ERIC Educational Resources Information Center

Brooks, Melanie Carol

2010-01-01

This single-subject case study explored one teacher's religious conversion to Islam and her workplace relationships in the United States and Egypt. Key findings of the study suggested that social context of schools influenced workplace relationships. As a Muslim-American teacher working in the American public schools, she was uncomfortable…

Japanese Education System: A Case Study Summary and Analysis. A Report. Research Today. International Studies.

ERIC Educational Resources Information Center

Wu, Angela

The Third International Mathematics and Science Study (TIMSS) results suggest to American citizens that compared to the United States' goal of excellence among nations, the U.S. is not on track with other nations. By contrast, Japan is consistently at the top of international rankings in mathematics and science. To gain insight into the Japanese…

Calories and sugars in boba milk tea: implications for obesity risk in Asian Pacific Islanders.

PubMed

Min, Jae Eun; Green, David B; Kim, Loan

2017-01-01

In the last several decades, obesity rates have reached epidemic proportions, and increases the risk for a host of comorbidities, including diabetes, cardiovascular disease, and certain kinds of cancers. Boba milk tea, first became popular in the 1990s throughout Asia, and has gained more popularity in the United States and in Europe since 2000. Currently, available nutrition data from online sites suggest this beverage contains high amounts of sugar and fat. One published nutrition study suggests that boba tea drinks are part of the larger group of sugar-sweetened beverages (SSB) because these beverages are usually sweetened with high-fructose corn syrup (HFCS). This study experimentally determined the sugar composition (sucrose, fructose, glucose, and melezitose) and calorific values of boba milk tea drinks and their components. Results suggested that boba drinks fit the US Dietary Guidelines definition of a SSB. One 16-ounce boba drink exceeds the upper limit of added sugar intake recommended by the 2015 US Dietary Guidelines Advisory Committee. The high caloric and sugar content of boba beverages pose public health concerns as they have the potential to further exacerbate the childhood obesity epidemic. Nutrition education targeting Asian populations should give special attention to boba tea as a SSB. Also, prudent public health recommendations should be suggested for moderate consumption of these beverages. With the growing popularity of boba beverages in the United States, the findings from this study provide public health practitioners with valuable data on how boba beverages compare with other SSBs.

A quantum chemical study of the mechanism for proton-coupled electron transfer leading to proton pumping in cytochrome c oxidase

NASA Astrophysics Data System (ADS)

Blomberg, Margareta R. A.; Siegbahn, Per E. M.

2010-10-01

The proton pumping mechanism in cytochrome c oxidase, the terminal enzyme in the respiratory chain, has been investigated using hybrid DFT with large chemical models. In previous studies, a gating mechanism was suggested based on electrostatic interpretations of kinetic experiments. The predictions from that analysis are tested here. The main result is that the suggestion of a positively charged transition state for proton transfer is confirmed, while some other suggestions for the gating are not supported. It is shown that a few critical relative energy values from the earlier studies are reproduced with quite high accuracy using the present model calculations. Examples are the forward barrier for proton transfer from the N-side of the membrane to the pump-loading site when the heme a cofactor is reduced, and the corresponding back leakage barrier when heme a is oxidised. An interesting new finding is an unexpected double-well potential for proton transfer from the N-side to the pump-loading site. In the intermediate between the two transition states found, the proton is bound to PropD on heme a. A possible purpose of this type of potential surface is suggested here. The accuracy of the present values are discussed in terms of their sensitivity to the choice of dielectric constant. Only one energy value, which is not critical for the present mechanism, varies significantly with this choice and is therefore less certain.

Effects of regular Taekwondo exercise on mood changes in children from multicultural families in South Korea: a pilot study

PubMed Central

Yang, Jung Su; Ko, Jae Myun; Roh, Hee Tae

2018-01-01

[Purpose] The purpose of this study was to investigate the effects of regular Taekwondo training on mood state in children from multicultural families. [Subjects and Methods] Twenty-four children participated in the study. Eight children from non-multicultural families were assigned to the non-multicultural family children group. The remaining 16 children from multicultural families were randomly assigned to the multicultural family children (control, n=8) or multicultural family children trained in Taekwondo (Taekwondo training, n=8) group. Mood state was measured using the Profile of Mood States (Tension-Anxiety, Depression-Dejection, Anger-Hostility, Vigor-Activity, Fatigue-Inertia, and Confusion-Bewilderment). [Results] Vigor-Activity scores increased significantly, whereas Tension-Anxiety and Anger-Hostility scores decreased significantly after intervention when compared with the pre-intervention scores in the multicultural family children trained in Taekwondo group. [Conclusion] It is suggested that regular Taekwondo training may be effective in improving the mood states of children from multicultural families living in Korea. PMID:29706693

Implementing the TARGET Model in Physical Education: Effects on Perceived Psychobiosocial and Motivational States in Girls.

PubMed

Bortoli, Laura; Bertollo, Maurizio; Filho, Edson; di Fronso, Selenia; Robazza, Claudio

2017-01-01

Grounded in achievement goal and self-determination theories, the purpose of this study was to investigate the effects of mastery and performance climate interventions on students' psychobiosocial (PBS) states and self-determined motivation. A first study was conducted to determine the validity of the measures. In a second study, two groups of female students ( N = 65, 14-15 years of age) took part in the investigation. A mastery-performance group participated in eight task-involving lessons and then in another set of eight ego-involving lessons. A performance-mastery group participated in ego-involving lessons and then in task-involving lessons. Findings revealed that the program was effective in changing PBS states and self-determined motivation in the performance-mastery group. In particular, participants in this group reported lower scores on pleasant/functional PBS states and self-determined motivation after the first phase of the intervention. Furthermore, lower levels of self-determined motivation were maintained after the second phase of the intervention, thereby suggesting detrimental carryover effects.

Hysteresis, reentrance, and glassy dynamics in systems of self-propelled rods

NASA Astrophysics Data System (ADS)

Kuan, Hui-Shun; Blackwell, Robert; Hough, Loren E.; Glaser, Matthew A.; Betterton, M. D.

2015-12-01

Nonequilibrium active matter made up of self-driven particles with short-range repulsive interactions is a useful minimal system to study active matter as the system exhibits collective motion and nonequilibrium order-disorder transitions. We studied high-aspect-ratio self-propelled rods over a wide range of packing fractions and driving to determine the nonequilibrium state diagram and dynamic properties. Flocking and nematic-laning states occupy much of the parameter space. In the flocking state, the average internal pressure is high and structural and mechanical relaxation times are long, suggesting that rods in flocks are in a translating glassy state despite overall flock motion. In contrast, the nematic-laning state shows fluidlike behavior. The flocking state occupies regions of the state diagram at both low and high packing fraction separated by nematic-laning at low driving and a history-dependent region at higher driving; the nematic-laning state transitions to the flocking state for both compression and expansion. We propose that the laning-flocking transitions are a type of glass transition that, in contrast to other glass-forming systems, can show fluidization as density increases. The fluid internal dynamics and ballistic transport of the nematic-laning state may promote collective dynamics of rod-shaped micro-organisms.

Hysteresis, reentrance, and glassy dynamics in systems of self-propelled rods.

PubMed

Kuan, Hui-Shun; Blackwell, Robert; Hough, Loren E; Glaser, Matthew A; Betterton, M D

2015-01-01

Nonequilibrium active matter made up of self-driven particles with short-range repulsive interactions is a useful minimal system to study active matter as the system exhibits collective motion and nonequilibrium order-disorder transitions. We studied high-aspect-ratio self-propelled rods over a wide range of packing fractions and driving to determine the nonequilibrium state diagram and dynamic properties. Flocking and nematic-laning states occupy much of the parameter space. In the flocking state, the average internal pressure is high and structural and mechanical relaxation times are long, suggesting that rods in flocks are in a translating glassy state despite overall flock motion. In contrast, the nematic-laning state shows fluidlike behavior. The flocking state occupies regions of the state diagram at both low and high packing fraction separated by nematic-laning at low driving and a history-dependent region at higher driving; the nematic-laning state transitions to the flocking state for both compression and expansion. We propose that the laning-flocking transitions are a type of glass transition that, in contrast to other glass-forming systems, can show fluidization as density increases. The fluid internal dynamics and ballistic transport of the nematic-laning state may promote collective dynamics of rod-shaped micro-organisms.

Identification of the Jπ=1- state in 218Ra populated via α decay of 222Th

NASA Astrophysics Data System (ADS)

Parr, E.; Smith, J. F.; Greenlees, P. T.; Smolen, M.; Papadakis, P.; Auranen, K.; Chapman, R.; Cullen, D. M.; Grahn, T.; Grocutt, L.; HerzáÅ, A.; Herzberg, R.-D.; Hodge, D.; Jakobsson, U.; Julin, R.; Juutinen, S.; Konki, J.; Leino, M.; McPeake, C.; Mengoni, D.; Mistry, A. K.; Mulholland, K. F.; O'Neill, G. G.; Pakarinen, J.; Partanen, J.; Peura, P.; Rahkila, P.; Ruotsalainen, P.; Sandzelius, M.; Sarén, J.; Scheck, M.; Scholey, C.; Sorri, J.; Stolze, S.; Taylor, M. J.; Uusitalo, J.

2016-07-01

The α decay of 222Th populating the low-lying Jπ=3- state, and also a proposed 1- state, in 218Ra has been observed. The observations suggest an excitation energy of 853 keV for the 1- state, which is 60 keV above the 3- state. The hindrance factors of these α decays give a possible boundary to the region of ground-state octupole deformation in the light-actinide nuclei. The relative positions of the Jπ=1- and 3- states suggest they are produced by an octupole-vibrational mechanism, as opposed to α clustering or rotations of a reflection-asymmetric octupole-deformed shape.

An application of Durkheim's theory of suicide to prison suicide rates in the United States.

PubMed

Tartaro, Christine; Lester, David

2005-06-01

E. Durkheim (1897) suggested that the societal rate of suicide might be explained by societal factors, such as marriage, divorce, and birth rates. The current study examined male prison suicide rates and suicide rates for men in the total population in the United States and found that variables based on Durkheim's theory of suicide explained prison suicide rates better than suicide rates for total population. Possible reasons for these findings are discussed.

Mental State Decoding in Adolescent Boys with Major Depressive Disorder versus Sex-Matched Healthy Controls.

PubMed

Mellick, William; Sharp, Carla

2016-01-01

Several adult depression studies have investigated mental state decoding, the basis for theory of mind, using the Reading the Mind in the Eyes Test. Findings have been mixed, but a comprehensive study found a greater severity of depression to be associated with poorer mental state decoding. Importantly, there has yet to be a similar study of adolescent depression. Converging evidence suggests that atypical mental state decoding may have particularly profound effects for psychosocial functioning among depressed adolescent boys. Adolescent boys with major depressive disorder (MDD, n = 33) and sex-matched healthy controls (HCs, n = 84) completed structured clinical interviews, self-report measures of psychopathology and the Child Eyes Test (CET). The MDD group performed significantly better than HCs on the CET overall (p = 0.002), underscored by greater accuracy for negatively valenced items (p = 0.003). Group differences on items depicting positive (p = 0.129) and neutral mental states (p = 0.081) were nonsignificant. Enhanced mental state decoding among depressed adolescent boys may play a role in the maintenance of and vulnerability to adolescent depression. Findings and implications are discussed. Limitations of this study include a reliance on self-report data for HC boys, as well as a lack of 'pure' depression among the boys with MDD. © 2016 S. Karger AG, Basel.

Applying Value Stream Mapping Technique for Production Improvement in a Manufacturing Company: A Case Study

NASA Astrophysics Data System (ADS)

Jeyaraj, K. L.; Muralidharan, C.; Mahalingam, R.; Deshmukh, S. G.

2013-01-01

The purpose of this paper is to explain how value stream mapping (VSM) is helpful in lean implementation and to develop the road map to tackle improvement areas to bridge the gap between the existing state and the proposed state of a manufacturing firm. Through this case study, the existing stage of manufacturing is mapped with the help of VSM process symbols and the biggest improvement areas like excessive TAKT time, production, and lead time are identified. Some modifications in current state map are suggested and with these modifications future state map is prepared. Further TAKT time is calculated to set the pace of production processes. This paper compares the current state and future state of a manufacturing firm and witnessed 20 % reduction in TAKT time, 22.5 % reduction in processing time, 4.8 % reduction in lead time, 20 % improvement in production, 9 % improvement in machine utilization, 7 % improvement in man power utilization, objective improvement in workers skill level, and no change in the product and semi finished product inventory level. The findings are limited due to the focused nature of the case study. This case study shows that VSM is a powerful tool for lean implementation and allows the industry to understand and continuously improve towards lean manufacturing.

Some methodological aspects of tectonic stress reconstruction based on geological indicators

NASA Astrophysics Data System (ADS)

Sim, Lidiya A.

2012-03-01

The impact of the initial heterogeneity in rocks on the distribution of slickensides (slip planes), which are used to reconstruct local stress-state, is discussed. The stress-state was reconstructed by a graphic variant of the cinematic method. A new type of stress-state - Variation of Stress-State Type (VSST) - is introduced. The VSST is characterized by dislocation vectors originated both by uniaxial compression and uniaxial tension in the same rock volume, i.e. coefficient μσ = 1-2R varies from +1 to -1. The reasons for differences between slip planes from those predicted by the model are discussed. The distribution of slip planes depends on the stress-state type (μσ coefficient) and on the initial heterogeneity of the rocks. A criterion for the identification of tectonic stress rank is suggested. It is based on the models of tectonic stress distribution in the fracture vicinities. Examples of results of tectonic stress studies are given. Studies of tectonic stresses based on geological indicators are of methodological and practical importance.

Coming to grips with a "new" state of consciousness: the study of rapid-eye-movement sleep in the 1960s.

PubMed

Morrison, Adrian R

2013-01-01

The recognition of rapid-eye-movement sleep (REM) and its association with dreaming in 1953 by Aserinsky and Kleitman opened a new world to explore in the brain. Discussions at two major symposia in the early 1960s reveal that a state with characteristics resembling both wakefulness and sleep was overturning accepted views of the regulation of the two states. Participants grappled with the idea that cortical activation could occur during sleep. They struggled with picking a name that would capture the essence of REM without focusing on just one aspect of the state. Questioning whether REM in cats could be homologous with that of humans suggested an anthropocentric focus on human dreaming as the essence of the state. The need for biochemical studies was evident given that deprivation of REM caused a rebound in the amount of subsequent REM, which indicated that simple synaptic activity could not support this phenomenon.

An Examination of the Indiana State University Aerospace Administration Program

NASA Technical Reports Server (NTRS)

Schwab, Gregory L.

2005-01-01

Declining enrollments in the Indiana State University (ISU) aerospace administration program prompted this case study. which evaluates the program in comparison with parallel programs at other universities, industry standards, and an independent audit. Survey instruments were administered to graduates, faculty, and employers for their views on competencies of an excellent aerospace administration program Results show the deficiency of the ISU program. Graduates, faculty, and employers rated all competencies-from moderate to considerable importance-similarly for an excellent program. Recommendations for program improvement were made, and suggestions for further research include studies to evaluate the effectiveness of a revised aerospace administration program.

Near-term high potential counties for SWECS

NASA Astrophysics Data System (ADS)

Osborn, W. C.; Downey, W. T.

1981-02-01

Up-to-date market information to manufacturers of small wind energy conversion system (SWECS) to assist them in developing marketing strategies for their products are provided. The data are arranged in a format that permits rapid identification of a particular location or market segment for further investigation. Extensive backup information by state and county in state SWECS Market reports are appended. It is suggested that the information are useful to SWECS manufacturers for planning new marketing and advertising activities. Background information essential to market studies is synthesized and an initial framework to start such a study is provided.

Stakeholder involvement in agri-environmental policy making--learning from a local- and a state-level approach in Germany.

PubMed

Prager, Katrin; Freese, Jan

2009-02-01

Recent European regulations for rural development emphasise the requirement to involve stakeholder groups and other appropriate bodies in the policy-making process. This paper presents two cases involving stakeholder participation in agri-environmental development and policy making, targeted at different policy-making levels. One study was undertaken in Lower Saxony where a local partnership developed and tested an agri-environmental prescription, which was later included in the state's menu of agri-environmental schemes. In Sachsen-Anhalt, state-facilitated stakeholder workshops including a mathematical model were used to optimise the programme planning and budget allocation at the state level. Both studies aimed at improving the acceptance of agri-environmental schemes. The authors gauge the effectiveness of the two approaches and discuss what lessons can be learned. The experience suggests that the approaches can complement one another and could also be applied to rural policy making.

The vacuum ultraviolet spectrum of krypton and xenon excimers excited in a cooled dc discharge

NASA Astrophysics Data System (ADS)

Gerasimov, G.; Krylov, B.; Loginov, A.; Zvereva, G.; Hallin, R.; Arnesen, A.; Heijkenskjöld, F.

1998-01-01

We present results of an experimental and theoretical study of the VUV spectra of krypton and xenon excimers excited by a dc discharge in a capillary tube cooled by liquid nitrogen. The studied spectral regions of 115-170 nm and 140-195 nm for krypton and xenon respectively correspond to transitions between the lowest excited dimer states 1u, 0u+ and the weakly bound ground state 0g+. A semiempirical method was suggested and applied to describe the experimental spectra and to estimate the temperature of the radiating plasma volume. Electron impact, transferring dimers from the ground state to the excited states, is shown to be an efficient excitation mechanism in the 100-850 hPa and the 10-50 mA pressure and discharge current ranges. The spectra obtained as well as the results of calculations corroborate the high rate of this mechanism.

Hybrid baryons in QCD

DOE PAGES

Dudek, Jozef J.; Edwards, Robert G.

2012-03-21

In this study, we present the first comprehensive study of hybrid baryons using lattice QCD methods. Using a large basis of composite QCD interpolating fields we extract an extensive spectrum of baryon states and isolate those of hybrid character using their relatively large overlap onto operators which sample gluonic excitations. We consider the spectrum of Nucleon and Delta states at several quark masses finding a set of positive parity hybrid baryons with quantum numbersmore » $$N_{1/2^+},\\,N_{1/2^+},\\,N_{3/2^+},\\, N_{3/2^+},\\,N_{5/2^+},\\,$$ and $$\\Delta_{1/2^+},\\, \\Delta_{3/2^+}$$ at an energy scale above the first band of `conventional' excited positive parity baryons. This pattern of states is compatible with a color octet gluonic excitation having $$J^{P}=1^{+}$$ as previously reported in the hybrid meson sector and with a comparable energy scale for the excitation, suggesting a common bound-state construction for hybrid mesons and baryons.« less

Good feelings in christianity and buddhism: religious differences in ideal affect.

PubMed

Tsai, Jeanne L; Miao, Felicity F; Seppala, Emma

2007-03-01

Affect valuation theory (AVT) predicts cultural variation in the affective states that people ideally want to feel (i.e., "ideal affect"). National and ethnic comparisons support this prediction: For instance, European Americans (EA) value high arousal positive (HAP) states (e.g., excitement) more and low arousal positive (LAP) states (e.g., calm) less than Hong Kong Chinese. In this article, the authors examine whether religions differ in the ideal affective states they endorse. The authors predicted that Christianity values HAP more and LAP less than Buddhism. In Study 1, they compared Christian and Buddhist practitioners' ideal affect. In Studies 2 and 3, they compared the endorsement of HAP and LAP in Christian and Buddhist classical texts (e.g., Gospels, Lotus Sutra) and contemporary self-help books (e.g., Your Best Life Now, Art of Happiness). Findings supported predictions, suggesting that AVT applies to religious and to national and ethnic cultures.

Theory-of-mind development influences suggestibility and source monitoring.

PubMed

Bright-Paul, Alexandra; Jarrold, Christopher; Wright, Daniel B

2008-07-01

According to the mental-state reasoning model of suggestibility, 2 components of theory of mind mediate reductions in suggestibility across the preschool years. The authors examined whether theory-of-mind performance may be legitimately separated into 2 components and explored the memory processes underlying the associations between theory of mind and suggestibility, independent of verbal ability. Children 3 to 6 years old completed 6 theory-of-mind tasks and a postevent misinformation procedure. Contrary to the model's prediction, a single latent theory-of-mind factor emerged, suggesting a single-component rather than a dual-component conceptualization of theory-of-mind performance. This factor provided statistical justification for computing a single composite theory-of-mind score. Improvements in theory of mind predicted reductions in suggestibility, independent of verbal ability (Study 1, n = 72). Furthermore, once attribution biases were controlled (Study 2, n = 45), there was also a positive relationship between theory of mind and source memory, but not recognition performance. The findings suggest a substantial, and possibly causal, association between theory-of-mind development and resistance to suggestion, driven specifically by improvements in source monitoring.

High-spin states and possible "stapler" band in 115In

NASA Astrophysics Data System (ADS)

Chen, Z. Q.; Wang, S. Y.; Liu, L.; Zhang, P.; Jia, H.; Qi, B.; Wang, S.; Sun, D. P.; Liu, C.; Li, Z. Q.; Wu, X. G.; Li, G. S.; He, C. Y.; Zheng, Y.; Zhu, L. H.

2015-04-01

High-spin states of 115In have been studied using the 114Cd (7Li,α 2 n ) reaction at a beam energy of 48 MeV. A total of 13 new transitions have been observed and added to the level scheme of 115In. Most of the states in 115In can be interpreted in terms of the weak coupling of a g9 /2 proton hole to the core states of 116Sn or a g7 /2 proton to the core states of 114Cd. A Δ I =1 band with the π (g9/2) -1⊗ν (h11/2) 2 configuration was suggested as an oblate band built on the "stapler" mechanism with the aid of the tilted axis cranking model based on covariant density functional theory.

The effect of challenge and threat states on performance: An examination of potential mechanisms

PubMed Central

Moore, Lee J; Vine, Samuel J; Wilson, Mark R; Freeman, Paul

2012-01-01

Challenge and threat states predict future performance; however, no research has examined their immediate effect on motor task performance. The present study examined the effect of challenge and threat states on golf putting performance and several possible mechanisms. One hundred twenty-seven participants were assigned to a challenge or threat group and performed six putts during which emotions, gaze, putting kinematics, muscle activity, and performance were recorded. Challenge and threat states were successively manipulated via task instructions. The challenge group performed more accurately, reported more favorable emotions, and displayed more effective gaze, putting kinematics, and muscle activity than the threat group. Multiple putting kinematic variables mediated the relationship between group and performance, suggesting that challenge and threat states impact performance at a predominately kinematic level. PMID:22913339

Quantum-state transfer through long-range correlated disordered channels

NASA Astrophysics Data System (ADS)

Almeida, Guilherme M. A.; de Moura, Francisco A. B. F.; Lyra, Marcelo L.

2018-05-01

We study quantum-state transfer in XX spin-1/2 chains where both communicating spins are weakly coupled to a channel featuring disordered on-site magnetic fields. Fluctuations are modeled by long-range correlated sequences with self-similar profile obeying a power-law spectrum. We show that the channel is able to perform almost perfect quantum-state transmissions even in the presence of significant amounts of disorder provided the degree of those correlations is strong enough, with the cost of having long transfer times and unavoidable timing errors. Still, we show that the lack of mirror symmetry in the channel does not affect much the likelihood of having high-quality outcomes. Our results suggest that coexistence between localized and delocalized states can diminish effects of static perturbations in solid-state devices for quantum communication.

Exploring the social brain in schizophrenia: left prefrontal underactivation during mental state attribution.

PubMed

Russell, T A; Rubia, K; Bullmore, E T; Soni, W; Suckling, J; Brammer, M J; Simmons, A; Williams, S C; Sharma, T

2000-12-01

Evidence suggests that patients with schizophrenia have a deficit in "theory of mind," i.e., interpretation of the mental state of others. The authors used functional magnetic resonance imaging (MRI) to investigate the hypothesis that patients with schizophrenia have a dysfunction in brain regions responsible for mental state attribution. Mean brain activation in five male patients with schizophrenia was compared to that in seven comparison subjects during performance of a task involving attribution of mental state. During performance of the mental state attribution task, the patients made more errors and showed less blood-oxygen-level-dependent signal in the left inferior frontal gyrus. To the authors' knowledge, this is the first functional MRI study to show a deficit in the left prefrontal cortex in schizophrenia during a socioemotional task.

Evidentiality and suggestibility: a new research venue.

PubMed

Aydin, Cağla; Ceci, Stephen J

2009-01-01

Recent research suggests that acquisition of mental-state language may influence conceptual development. We examine this possibility by investigating the conceptual links between evidentiality in language and suggestibility. Young children are disproportionately suggestible and tend to change their reports or memories when questioned. The authors discuss the extent to which components of mental-state understanding, specifically representational understanding and understanding origins of knowledge, are implicated in improvements in resistance to suggestions and comprehending evidentiality. The authors also review social-psychological evidence that has implications for evidential understanding. Integration of the literature on both topics is followed by suggestions for new research directions.

State recommendations on approaches to LANDSAT

NASA Technical Reports Server (NTRS)

Bay, S. M.; Wubker, P.

1977-01-01

The feasibility of continuing the LANDSAT program is contingent upon the success of the technology transfer process to state and local governments. The focus of these concerns can be generally expressed in terms of these issue areas: (1) user needs, in terms of awareness, technical capabilities, and training; (2) product availability and pricing; and (3) roles and communication links, in terms of federal and state governments, the private sector, and the universities. The perspective of the states on these issues are classified. Where possible, alternative strategies for accomplishing the satellite technology transfer for effective state implementation are suggested. Those suggestions are based on the recommendations offered by the state and local user community.

The relationship between cigarette taxes and child maltreatment.

PubMed

McLaughlin, Michael

2018-05-01

Prior research suggests that income and child maltreatment are related, but questions remain about the specific types of economic factors that affect the risk of maltreatment. The need to understand the role of economics in child welfare is critical, given the significant public health costs of child maltreatment. One factor that has been overlooked is regressive taxation. This study addresses this need by examining whether state-level changes in cigarette tax rates predict changes in state-level child maltreatment rates. The results of both a fixed effects (FE) and a fixed effects instrumental variables (FE-IV) estimator show that increases in state cigarette tax rates are followed by increases in child abuse and neglect. An additional test finds that increases in the sales tax (another tax deemed to be regressive) also predict increases in child maltreatment rates. Taken as a whole, the findings suggest that regressive taxes have a significant effect on the risk of child maltreatment. Copyright © 2018 Elsevier Ltd. All rights reserved.

Pupil diameter tracks changes in control state predicted by the adaptive gain theory of locus coeruleus function

PubMed Central

Gilzenrat, Mark S.; Nieuwenhuis, Sander; Jepma, Marieke; Cohen, Jonathan D.

2010-01-01

An important dimension of cognitive control is the adaptive regulation of the balance between exploitation (pursuing known sources of reward) and exploration (seeking new ones) in response to changes in task utility. Recent studies have suggested that the locus coeruleus–norepinephrine system may play an important role in this function and that pupil diameter can be used to index locus coeruleus activity. On the basis of this, we reasoned that pupil diameter may correlate closely with control state and associated changes in behavior. Specifically, we predicted that increases in baseline pupil diameter would be associated with decreases in task utility and disengagement from the task (exploration), whereas reduced baseline diameter (but increases in task-evoked dilations) would be associated with task engagement (exploitation). Findings in three experiments were consistent with these predictions, suggesting that pupillometry may be useful as an index of both control state and, indirectly, locus coeruleus function. PMID:20498349

The effects of soy on freezable bread dough: a magnetic resonance study.

PubMed

Simmons, Amber L; Vodovotz, Yael

2012-11-15

Hygroscopic soy ingredients were hypothesised to slow the rate of water migration in unleavened bread dough during frozen storage. Thawed soy (18% dry weight) and wheat dough samples were assessed using non-destructive nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) for up to 8 wks frozen storage time. MRI suggested a spatially homogeneous, net increase in proton mobility with frozen storage and, with solution state proton NMR, distinct "free" and "bound" states were discerned. T(2) relaxation times of the majority proton population suggested increased mobility with frozen storage time, and statistical difference from the fresh sample was seen later for the soy samples than the wheat samples. As seen by (13)C-solid state NMR, the crystallinity of the starch was not affected by either soy addition or frozen storage. In conclusion, addition of soy to bakery products led to slightly enhanced preservation of "fresh" characteristics of the dough during frozen storage. Copyright © 2012 Elsevier Ltd. All rights reserved.

The gas phase structure of transition metal dihydrides

NASA Astrophysics Data System (ADS)

Demuynck, Jean; Schaefer, Henry F.

1980-01-01

ESR and infrared spectroscopic measurements on matrix isolated MnH2 and CrH2 have recently suggested that these simple molecules may be bent. This result would be the opposite of that found experimentally for the transition metal dihalides MX2, known to be linear. Here the geometrical structure of MnH2 has been investigated by molecular electronic structure theory. A large contracted Gaussian basis set [Mn(14s11p6p/9s8p3d), H(5s1p/3s1p)] was used in conjunction with self-consistent field and configuration interaction methods. These suggest that the 6A1 ground state of MnH2 is linear. Further studies of the 3A1 state (one of several low-lying states) of TiH2 also favor linearity, although this potential energy surface is extremely flat with respect to bending. Thus it appears probable that most MH2 molecules, like the related MX2 family, are linear.

Assemblages of endophagous insects on Asteraceae in São Paulo cerrados.

PubMed

Almeida, Adriana M; Fonseca, Carlos R; Prado, Paulo I; Almeida-Neto, Mário; Diniz, Soraia; Kubota, Umberto; Braun, Marina R; Raimundo, Rafael L G; Anjos, Luciano A; Mendonça, Tehra G; Futada, Silvia M; Lewinsohn, Thomas M

2006-01-01

A survey of the endophagous insects fauna associated to Asteraceae capitula was carried out from 2000 to 2002 in eight cerrado sensu stricto sites located in the Brazilian state of Sdo Paulo. Sixty-four endophagous species of Diptera and Lepidoptera were recorded from 49 asteracean host plants. Approximately half of the species were obtained from a single locality, with a large proportion emerging from a single sample (unicates). Thirty percent of the species were singletons (i.e. only one individual was recorded). The large proportion of rare species suggests a high species turnover among localities. Lepidopteran species were recorded on more host species than dipterans, confirming their more polyphagous food habit, also observed in other Brazilian biomes and in Europe. We conclude that the studied cerrado localities, all within São Paulo State, are isolated with its invertebrate fauna composed of many rare and exclusive species. We suggest that the maintenance of Asteraceae biodiversity and their endophagous insects depend on the conservation of all cerrado remnants in the state.

The Illusion of the Positive: The impact of natural and induced mood on older adults’ false recall

PubMed Central

Emery, Lisa; Hess, Thomas M.; Elliot, Tonya

2012-01-01

Recent research suggests that affective and motivational processes can influence age differences in memory. In the current study, we examine the impact of both natural and induced mood state on age differences in false recall. Older and younger adults performed a version of the Deese-Roediger-McDermott (DRM; Roediger & McDermott, 1995) false memory paradigm in either their natural mood state or after a positive or negative mood induction. Results indicated that, after accounting for age differences in basic cognitive function, age-related differences in positive mood during the testing session were related to increased false recall in older adults. Inducing older adults into a positive mood also exacerbated age differences in false memory. In contrast, veridical recall did not appear to be systematically influenced by mood. Together, these results suggest that positive mood states can impact older adults’ information processing and potentially increase underlying cognitive age differences. PMID:22292431

The illusion of the positive: the impact of natural and induced mood on older adults' false recall.

PubMed

Emery, Lisa; Hess, Thomas M; Elliot, Tonya

2012-11-01

Recent research suggests that affective and motivational processes can influence age differences in memory. In the current study, we examine the impact of both natural and induced mood state on age differences in false recall. Older and younger adults performed a version of the Deese-Roediger-McDermott (DRM; Roediger & McDermott, 1995 , Journal of Experimental Psychology: Learning, Memory, and Cognition, 21, 803) false memory paradigm in either their natural mood state or after a positive or negative mood induction. Results indicated that, after accounting for age differences in basic cognitive function, age-related differences in positive mood during the testing session were related to increased false recall in older adults. Inducing older adults into a positive mood also exacerbated age differences in false memory. In contrast, veridical recall did not appear to be systematically influenced by mood. Together, these results suggest that positive mood states can impact older adults' information processing and potentially increase underlying cognitive age differences.

Molecular dynamics study on the microscopic details of the evaporation of water.

PubMed

Mason, Phillip E

2011-06-16

Molecular dynamics simulations were conducted on a drop of water (containing 4890 TIP3P waters) at 350 K. About 70 evaporation events were found and characterized in enough detail to determine significant patterns relating to the mechanism of evaporation. It was found that in almost all evaporation events that a single, high-energy state immediately preceded the evaporation event. In ∼50% of the cases, this high-energy state involved a short oxygen-oxygen distance, suggesting a van der Waals collision, whereas in the remaining cases, a short hydrogen-hydrogen distance was found, suggesting an electrostatic "collision". Of the high-energy states that led to evaporation, about half occurred when the coordination number of water was 1, and about half, when the coordination number was 2. It was found that the 1-coordinated waters (∼1% of the surface waters) and 2-coordinated waters (6% of the surface waters) were responsible for almost all the evaporation events. © 2011 American Chemical Society

Safety performance of traffic phases and phase transitions in three phase traffic theory.

PubMed

Xu, Chengcheng; Liu, Pan; Wang, Wei; Li, Zhibin

2015-12-01

Crash risk prediction models were developed to link safety to various phases and phase transitions defined by the three phase traffic theory. Results of the Bayesian conditional logit analysis showed that different traffic states differed distinctly with respect to safety performance. The random-parameter logit approach was utilized to account for the heterogeneity caused by unobserved factors. The Bayesian inference approach based on the Markov Chain Monte Carlo (MCMC) method was used for the estimation of the random-parameter logit model. The proposed approach increased the prediction performance of the crash risk models as compared with the conventional logit model. The three phase traffic theory can help us better understand the mechanism of crash occurrences in various traffic states. The contributing factors to crash likelihood can be well explained by the mechanism of phase transitions. We further discovered that the free flow state can be divided into two sub-phases on the basis of safety performance, including a true free flow state in which the interactions between vehicles are minor, and a platooned traffic state in which bunched vehicles travel in successions. The results of this study suggest that a safety perspective can be added to the three phase traffic theory. The results also suggest that the heterogeneity between different traffic states should be considered when estimating the risks of crash occurrences on freeways. Copyright © 2015 Elsevier Ltd. All rights reserved.

Induction of quiescence (G0) in bone marrow stromal stem cells enhances their stem cell characteristics.

PubMed

Rumman, Mohammad; Majumder, Abhijit; Harkness, Linda; Venugopal, Balu; Vinay, M B; Pillai, Malini S; Kassem, Moustapha; Dhawan, Jyotsna

2018-05-17

Several studies have suggested that bone marrow stromal steam cells (BMSC) exist in a quiescent state (G0) within the in vivo niche; however, an explicit analysis of the biology of G0 state-BMSC has not been reported. We hypothesized that induction of G0 in BMSC might enhance their stem cell properties. Thus, we induced quiescence in BMSC in vitro by (a) suspension culture in a viscous medium or (b) culture on soft polyacrylamide substrate; and examined their molecular and functional phenotype. Induction of G0 was confirmed by bromo-deoxyuridine (BrdU) labelling and analysis of cell cycle gene expression. Upon reactivation and re-entry into cell cycle, G0 state-BMSC exhibited enhanced clonogenic self-renewal, preferential differentiation into osteoblastic rather than adipocytic cells and increased ectopic bone formation when implanted subcutaneously in vivo in immune-deficient mice, compared to asynchronous proliferating (pre-G0) BMSC. Global gene expression profiling revealed reprogramming of the transcriptome during G0 state including significant alterations in relevant pathways and expression of secreted factors, suggesting altered autocrine and paracrine signaling by G0 state-BMSC and a possible mechanism for enhanced bone formation. G0 state-BMSC might provide a clinically relevant model for understanding the in vivo biology of BMSC. Copyright © 2018. Published by Elsevier B.V.

Correlation of within-individual fluctuation of depressed mood with prefrontal cortex activity during verbal working memory task: optical topography study

NASA Astrophysics Data System (ADS)

Sato, Hiroki; Aoki, Ryuta; Katura, Takusige; Matsuda, Ryoichi; Koizumi, Hideaki

2011-12-01

Previous studies showed that interindividual variations in mood state are associated with prefrontal cortex (PFC) activity. In this study, we focused on the depressed-mood state under natural circumstances and examined the relationship between within-individual changes over time in this mood state and PFC activity. We used optical topography (OT), a functional imaging technique based on near-infrared spectroscopy, to measure PFC activity for each participant in three experimental sessions repeated at 2-week intervals. In each session, the participants completed a self-report questionnaire of mood state and underwent OT measurement while performing verbal and spatial working memory (WM) tasks. The results showed that changes in the depressed-mood score between successive sessions were negatively correlated with those in the left PFC activation for the verbal WM task (ρ = -0.56, p < 0.05). In contrast, the PFC activation for the spatial WM task did not co-vary with participants' mood changes. We thus demonstrated that PFC activity during a verbal WM task varies depending on the participant's depressed mood state, independent of trait factors. This suggests that using optical topography to measure PFC activity during a verbal WM task can be used as a potential state marker for an individual's depressed mood state.

Valuing Health Using Time Trade-Off and Discrete Choice Experiment Methods: Does Dimension Order Impact on Health State Values?

PubMed

Mulhern, Brendan; Shah, Koonal; Janssen, Mathieu F Bas; Longworth, Louise; Ibbotson, Rachel

2016-01-01

Health states defined by multiattribute instruments such as the EuroQol five-dimensional questionnaire with five response levels (EQ-5D-5L) can be valued using time trade-off (TTO) or discrete choice experiment (DCE) methods. A key feature of the tasks is the order in which the health state dimensions are presented. Respondents may use various heuristics to complete the tasks, and therefore the order of the dimensions may impact on the importance assigned to particular states. To assess the impact of different EQ-5D-5L dimension orders on health state values. Preferences for EQ-5D-5L health states were elicited from a broadly representative sample of members of the UK general public. Respondents valued EQ-5D-5L health states using TTO and DCE methods across one of three dimension orderings via face-to-face computer-assisted personal interviews. Differences in mean values and the size of the health dimension coefficients across the arms were compared using difference testing and regression analyses. Descriptive analysis suggested some differences between the mean TTO health state values across the different dimension orderings, but these were not systematic. Regression analysis suggested that the magnitude of the dimension coefficients differs across the different dimension orderings (for both TTO and DCE), but there was no clear pattern. There is some evidence that the order in which the dimensions are presented impacts on the coefficients, which may impact on the health state values provided. The order of dimensions is a key consideration in the design of health state valuation studies. Copyright © 2016. Published by Elsevier Inc.

Three Spectral States of the Disk X-Ray Emission of the Black-Hole Candidate 4U 1630- 47

NASA Astrophysics Data System (ADS)

Abe, Yukiko; Fukazawa, Yasushi; Kubota, Aya; Kasama, Daisuke; Makishima, Kazuo

2005-08-01

We studied a time history of X-ray spectral states of a black-hole candidate, 4U 1630-47, utilizing data from a number of monitoring observations with the Rossi X-Ray Timing Explorer over 1996-2004. These observations covered five outbursts of 4U 1630-47, and recorded typical features of the high/soft states. The spectra in the high/soft states can be classified into three states. The first state is explained by a concept of the standard accretion disk picture. The second appears in the very high state, where a dominant hard component is seen and the disk radius apparently becomes too small. These phenomena are explained by the effect of inverse Compton scattering of disk photons, as shown by Kubota, Makishima, and Ebisawa (2001, ApJ, 560, L147) for GRO J1655-40. The third shows that the disk luminosity varies in proportion to Tin2, rather than Tin4, where Tin is the inner-disk temperature. This state suggests an optically-thick and advection-dominated slim disk, as given by Kubota and Makishima (2004, ApJ, 601, 428) for XTE J1550-564. The second and third states appear, with good reproducibility, when Tin and the total X-ray luminosity are higher than 1.2keV and ˜ 2.5 × 1038(D/10 kpc)² [cosθ/(1/√3)]-1 erg s-1, respectively, where D is the distance to the object and θ is the inclination angle to the disk. The results suggest that these spectral states commonly appear among black-hole binaries under high accretion rates.

Targeting excited states in all-trans polyenes with electron-pair states.

PubMed

Boguslawski, Katharina

2016-12-21

Wavefunctions restricted to electron pair states are promising models for strongly correlated systems. Specifically, the pair Coupled Cluster Doubles (pCCD) ansatz allows us to accurately describe bond dissociation processes and heavy-element containing compounds with multiple quasi-degenerate single-particle states. Here, we extend the pCCD method to model excited states using the equation of motion (EOM) formalism. As the cluster operator of pCCD is restricted to electron-pair excitations, EOM-pCCD allows us to target excited electron-pair states only. To model singly excited states within EOM-pCCD, we modify the configuration interaction ansatz of EOM-pCCD to contain also single excitations. Our proposed model represents a simple and cost-effective alternative to conventional EOM-CC methods to study singly excited electronic states. The performance of the excited state models is assessed against the lowest-lying excited states of the uranyl cation and the two lowest-lying excited states of all-trans polyenes. Our numerical results suggest that EOM-pCCD including single excitations is a good starting point to target singly excited states.

Alternative stable states and phase shifts in coral reefs under anthropogenic stress.

PubMed

Fung, Tak; Seymour, Robert M; Johnson, Craig R

2011-04-01

Ecosystems with alternative stable states (ASS) may shift discontinuously from one stable state to another as environmental parameters cross a threshold. Reversal can then be difficult due to hysteresis effects. This contrasts with continuous state changes in response to changing environmental parameters, which are less difficult to reverse. Worldwide degradation of coral reefs, involving "phase shifts" from coral to algal dominance, highlights the pressing need to determine the likelihood of discontinuous phase shifts in coral reefs, in contrast to continuous shifts with no ASS. However, there is little evidence either for or against the existence of ASS for coral reefs. We use dynamic models to investigate the likelihood of continuous and discontinuous phase shifts in coral reefs subject to sustained environmental perturbation by fishing, nutrification, and sedimentation. Our modeling results suggest that coral reefs with or without anthropogenic stress can exhibit ASS, such that discontinuous phase shifts can occur. We also find evidence to support the view that high macroalgal growth rates and low grazing rates on macroalgae favor ASS in coral reefs. Further, our results suggest that the three stressors studied, either alone or in combination, can increase the likelihood of both continuous and discontinuous phase shifts by altering the competitive balance between corals and algae. However, in contrast to continuous phase shifts, we find that discontinuous shifts occur only in model coral reefs with parameter values near the extremes of their empirically determined ranges. This suggests that continuous shifts are more likely than discontinuous shifts in coral reefs. Our results also suggest that, for ecosystems in general, tackling multiple human stressors simultaneously maximizes resilience to phase shifts, ASS, and hysteresis, leading to improvements in ecosystem health and functioning.

Spontaneous pre-stimulus fluctuations in the activity of right fronto-parietal areas influence inhibitory control performance

PubMed Central

Chavan, Camille F.; Manuel, Aurelie L.; Mouthon, Michael; Spierer, Lucas

2013-01-01

Inhibitory control refers to the ability to suppress planned or ongoing cognitive or motor processes. Electrophysiological indices of inhibitory control failure have been found to manifest even before the presentation of the stimuli triggering the inhibition, suggesting that pre-stimulus brain-states modulate inhibition performance. However, previous electrophysiological investigations on the state-dependency of inhibitory control were based on averaged event-related potentials (ERPs), a method eliminating the variability in the ongoing brain activity not time-locked to the event of interest. These studies thus left unresolved whether spontaneous variations in the brain-state immediately preceding unpredictable inhibition-triggering stimuli also influence inhibitory control performance. To address this question, we applied single-trial EEG topographic analyses on the time interval immediately preceding NoGo stimuli in conditions where the responses to NoGo trials were correctly inhibited [correct rejection (CR)] vs. committed [false alarms (FAs)] during an auditory spatial Go/NoGo task. We found a specific configuration of the EEG voltage field manifesting more frequently before correctly inhibited responses to NoGo stimuli than before FAs. There was no evidence for an EEG topography occurring more frequently before FAs than before CR. The visualization of distributed electrical source estimations of the EEG topography preceding successful response inhibition suggested that it resulted from the activity of a right fronto-parietal brain network. Our results suggest that the fluctuations in the ongoing brain activity immediately preceding stimulus presentation contribute to the behavioral outcomes during an inhibitory control task. Our results further suggest that the state-dependency of sensory-cognitive processing might not only concern perceptual processes, but also high-order, top-down inhibitory control mechanisms. PMID:23761747

States with low non-fatal injury rates have high fatality rates and vice-versa.

PubMed

Mendeloff, John; Burns, Rachel

2013-05-01

State-level injury rates or fatality rates are sometimes used in studies of the impact of various safety programs or other state policies. How much does the metric used affect the view of relative occupational risks among U.S. states? This paper uses a measure of severe injuries (fatalities) and of less severe injuries (non-fatal injuries with days away from work, restricted work, or job transfer-DART) to examine that issue. We looked at the correlation between the average DART injury rate (from the BLS Survey of Occupational Injuries and Illnesses) and an adjusted average fatality rate (from the BLS Census of Fatal Occupational Injuries) in the construction sector for states for 2003-2005 and for 2006-2008. The RAND Human Subjects Protection Committee determined that this study was exempt from review. The correlations between the fatal and non-fatal injury rates were between -0.30 and -0.70 for all construction and for the subsector of special trade contractors. The negative correlation was much smaller between the rate of fatal falls from heights and the rate of non-fatal falls from heights. Adjusting for differences in the industry composition of the construction sector across states had minor effects on these results. Although some have suggested that fatal and non-fatal injury rates should not necessarily be positively correlated, no one has suggested that the correlation is negative, which is what we find. We know that reported non-fatal rates are influenced by workers' compensation benefits and other factors. Fatality rates appear to be a more valid measure of risk. Efforts to explain the variations that we find should be undertaken. Copyright © 2012 Wiley Periodicals, Inc.

A Systematic Review of the Prevalence of Herb Usage Among Racial/Ethnic Minorities in the United States

PubMed Central

Whelan, Julia; White, Laura F.; Filippelli, Amanda C.; Bharmal, Nazleen; Kaptchuk, Ted J.

2015-01-01

Clinical studies display a wide range of herb use prevalence among racial/ethnic minorities in the United States. We searched databases indexing the literature including CINAHL, EMBASE, Global Health, CAB Abstracts, and Medline. We included studies that reported herbal medicine prevalence among ethnic minorities, African American, Hispanic, or Asian adults living in the United States. Data from 108 included studies found the prevalence of herb use by African Americans was 17 % (range 1–46 %); for Hispanics, 30 % (4–100 %); and for Asians, 30 % (2–73 %). Smaller studies were associated with higher reported herb use (p = 0.03). There was a significant difference (p = 0.01) between regional and national studies with regional studies reporting higher use. While herb usage surveys in racial/ethnic minorities show great variability, indications suggest high prevalence. More research is needed to understand herb use among ethnic/racial minorities, reasons for use, and barriers to disclosure of use to clinicians. PMID:22723252

Equally inequitable? A cross-national comparative study of racial health inequalities in the United States and Canada.

PubMed

Ramraj, Chantel; Shahidi, Faraz Vahid; Darity, William; Kawachi, Ichiro; Zuberi, Daniyal; Siddiqi, Arjumand

2016-07-01

Prior research suggests that racial inequalities in health vary in magnitude across societies. This paper uses the largest nationally representative samples available to compare racial inequalities in health in the United States and Canada. Data were obtained from ten waves of the National Health Interview Survey (n = 162,271,885) and the Canadian Community Health Survey (n = 19,906,131) from 2000 to 2010. We estimated crude and adjusted odds ratios, and risk differences across racial groups for a range of health outcomes in each country. Patterns of racial health inequalities differed across the United States and Canada. After adjusting for covariates, black-white and Hispanic-white inequalities were relatively larger in the United States, while aboriginal-white inequalities were larger in Canada. In both countries, socioeconomic factors did not explain inequalities across racial groups to the same extent. In conclusion, while racial inequalities in health exist in both the United States and Canada, the magnitudes of these inequalities as well as the racial groups affected by them, differ considerably across the two countries. This suggests that the relationship between race and health varies as a function of the societal context in which it operates. Copyright © 2016 Elsevier Ltd. All rights reserved.

Role of atomic bonding for compound and glass formation in Ni-Si, Pd-Si, and Ni-B systems

NASA Astrophysics Data System (ADS)

Tanaka, K.; Saito, T.; Suzuki, K.; Hasegawa, R.

1985-11-01

Valence electronic structures of crystalline compounds and glassy alloys of Ni silicides, Pd silicides, and Ni borides are studied by soft-x-ray spectroscopy over wide ranges of Si and B concentrations. The samples prepared include bulk compounds, glassy ribbons, and amorphous sputtered films. Silicon Kβ emissions of Ni and Pd silicides generally consist of a prominent peak fixed at ~=4.5 and ~=5.8 eV below the Fermi level EF, respectively, with a shoulder near EF which grows and shifts toward lower energy with increasing Si concentration. The former is identified as due to Si p-like states forming Si 3p-Ni 3d or Si 3p-Pd 4d bonding states while the latter as due to the corresponding antibonding states. Ni L3 and Pd L3 emissions of these silicides indicate that Ni 3d and Pd 4d states lie between the above two states. These local electronic configurations are consistent with partial-density-of-states (PDOS) calculations performed by Bisi and Calandra. Similar electronic configurations are suggested for Ni borides from B Kα and Ni L3 emissions. Differences of emission spectra between compounds and glasses of similar compositions are rather small, but some enhancement of the contribution of antibonding states to the PDOS near EF is suggested for certain glasses over that of the corresponding compounds. These features are discussed in connection with the compound stability and glass formability.

Moving beyond relationship and task conflict: toward a process-state perspective.

PubMed

DeChurch, Leslie A; Mesmer-Magnus, Jessica R; Doty, Dan

2013-07-01

Teams are formed to benefit from an expanded pool of expertise and experience, yet 2 aspects of the conflict stemming from those core differences will ultimately play a large role in determining team viability and productivity: conflict states and conflict processes. The current study theoretically reorganizes the literature on team conflict--distinguishing conflict states from conflict processes--and details the effects of each on team effectiveness. Findings from a meta-analytic cumulation of 45 independent studies (total number of teams = 3,218) suggest states and processes are distinct and important predictors of team performance and affective outcomes. Controlling for conflict states (i.e., task and relationship conflict), conflict processes explain an additional 13% of the variance in both team performance and team affective outcomes. Furthermore, findings reveal particular conflict processes that are beneficial and others detrimental to teams. The truth about team conflict: conflict processes, that is, how teams interact regarding their differences, are at least as important as conflict states, that is, the source and intensity of their perceived incompatibilities. PsycINFO Database Record (c) 2013 APA, all rights reserved.

Budget- and Priority-Setting Criteria at State Health Agencies in Times of Austerity: A Mixed-Methods Study

PubMed Central

Resnick, Beth; Kass, Nancy; Sellers, Katie; Young, Jessica; Bernet, Patrick; Jarris, Paul

2014-01-01

Objectives. We examined critical budget and priority criteria for state health agencies to identify likely decision-making factors, pressures, and opportunities in times of austerity. Methods. We have presented findings from a 2-stage, mixed-methods study with state public health leaders regarding public health budget- and priority-setting processes. In stage 1, we conducted hour-long interviews in 2011 with 45 health agency executive and division or bureau leaders from 6 states. Stage 2 was an online survey of 207 executive and division or bureau leaders from all state health agencies (66% response rate). Results. Respondents identified 5 key criteria: whether a program was viewed as “mission critical,” the seriousness of the consequences of not funding the program, financing considerations, external directives and mandates, and the magnitude of the problem the program addressed. Conclusions. We have presented empirical findings on criteria used in state health agency budgetary decision-making. These criteria suggested a focus and interest on core public health and the largest public health problems with the most serious ramifications. PMID:24825212

Nationwide Benthic Macroinvertebrate Assemblage Multimetric Indices: Identifying Inconsistencies and Limitations in Reporting Stream Impairment Status, USA

NASA Astrophysics Data System (ADS)

Lau, J. K.; Lauer, T. E.

2015-07-01

The objective of this study was to identify the current status of stream water-quality assessment and reporting methods for four states in the Ohio River basin (Indiana, Ohio, Tennessee, and Virginia), as required by the 305(b) section of the United States (US) Clean Water Act. Specifically, we clarified the discrepancies that exist among stream-impairment status classified by benthic macroinvertebrate multimetric indices (MMIs) and depicted using Geographic Information Systems shapefiles. In addition, we provided guidance in solving some of the comparability problems that arise when developing state-specific MMIs and depicting stream-impairment status using Geographic Information Systems technology. The MMI variation among states and differences in shapefile formats resulted in a nationwide dataset, which cannot be directly compared. Incorporating the changes suggested in this study allow for a uniform assessment and reporting method nationwide. Successful implementation of these changes would strengthen the US Environmental Protection Agency efforts to identify impaired streams and sources of those impairments without the limitations of state-by-state .developed assessment methods.

Budget- and priority-setting criteria at state health agencies in times of austerity: a mixed-methods study.

PubMed

Leider, Jonathon P; Resnick, Beth; Kass, Nancy; Sellers, Katie; Young, Jessica; Bernet, Patrick; Jarris, Paul

2014-06-01

We examined critical budget and priority criteria for state health agencies to identify likely decision-making factors, pressures, and opportunities in times of austerity. We have presented findings from a 2-stage, mixed-methods study with state public health leaders regarding public health budget- and priority-setting processes. In stage 1, we conducted hour-long interviews in 2011 with 45 health agency executive and division or bureau leaders from 6 states. Stage 2 was an online survey of 207 executive and division or bureau leaders from all state health agencies (66% response rate). Respondents identified 5 key criteria: whether a program was viewed as "mission critical," the seriousness of the consequences of not funding the program, financing considerations, external directives and mandates, and the magnitude of the problem the program addressed. We have presented empirical findings on criteria used in state health agency budgetary decision-making. These criteria suggested a focus and interest on core public health and the largest public health problems with the most serious ramifications.

Disparity between state fish consumption advisory systems for Methylmercury and US Environmental Protection Agency recommendations: a case study of the South Central United States

USGS Publications Warehouse

Adams, Kimberly; Drenner, Ray W.; Chumchal, Matthew M.; Donato, David I.

2015-01-01

Fish consumption advisories are used to inform citizens in the United States about noncommercial game fish with hazardous levels of methylmercury (MeHg). The US Environmental Protection Agency (USEPA) suggests issuing a fish consumption advisory when concentrations of MeHg in fish exceed a human health screening value of 300 ng/g. However, states have authority to develop their own systems for issuing fish consumption advisories for MeHg. Five states in the south central United States (Arkansas, Louisiana, Mississippi, Oklahoma, and Texas) issue advisories for the general human population when concentrations of MeHg exceed 700 ng/g to 1000 ng/g. The objective of the present study was to estimate the increase in fish consumption advisories that would occur if these states followed USEPA recommendations. The authors used the National Descriptive Model of Mercury in Fish to estimate the mercury concentrations in 5 size categories of largemouth bass–equivalent fish at 766 lentic and lotic sites within the 5 states. The authors found that states in this region have not issued site-specific fish consumption advisories for most of the water bodies that would have such advisories if USEPA recommendations were followed. One outcome of the present study may be to stimulate discussion between scientists and policy makers at the federal and state levels about appropriate screening values to protect the public from the health hazards of consuming MeHg-contaminated game fish.

Suggestibility and state anxiety: how the two concepts relate in a source identification paradigm.

PubMed

Ridley, Anne M; Clifford, Brian R

2006-01-01

Source identification tests provide a stringent method for testing the suggestibility of memory because they reduce response bias and experimental demand characteristics. Using the techniques and materials of Maria Zaragoza and her colleagues, we investigated how state anxiety affects the ability of undergraduates to identify correctly the source of misleading post-event information. The results showed that individuals high in state anxiety were less likely to make source misattributions of misleading information, indicating lower levels of suggestibility. This effect was strengthened when forgotten or non-recognised misleading items (for which a source identification task is not possible) were excluded from the analysis. Confidence in the correct attribution of misleading post-event information to its source was significantly less than confidence in source misattributions. Participants who were high in state anxiety tended to be less confident than those lower in state anxiety when they correctly identified the source of both misleading post-event information and non-misled items. The implications of these findings are discussed, drawing on the literature on anxiety and cognition as well as suggestibility.

Temperature-dependent reproductive development of Lygus hesperus (Hemiptera: Miridae)

USDA-ARS?s Scientific Manuscript database

Recent studies to elucidate relationships between the western tarnished plant bug, L. hesperus Knight, and injury to cotton (Gossypium spp.) have identified important differences in feeding behaviors among adults of different gender and reproductive states. These findings suggest a need for improved...

RAPID CONCENTRATION OF VIRUSES FROM WATER - PHASE I

EPA Science Inventory

In the United States, several high profile outbreaks of waterborne illness during the past 15 years have highlighted the need for solutions to drinking water contamination.  Several recent studies suggest that approximately 20 percent of the surface and ground source waters...

Cultural Diversity in the Workplace: The State of the Field.

ERIC Educational Resources Information Center

Fine, Marlene G.

1996-01-01

Reviews three broad categories of research on cultural diversity in the workplace: general overviews, theoretical perspectives, and empirical research studies. Offers an explanation for the paucity of research on the topic, and suggests topics and methods for future research. (SR)

Greater Perceived Age Discrimination in England than the United States: Results from HRS and ELSA

PubMed Central

Zaninotto, Paola; Steptoe, Andrew

2015-01-01

Objectives. We examined cross-national differences in perceptions of age discrimination in England and the United States. Under the premise that the United States has had age discrimination legislation in place for considerably longer than England, we hypothesized that perceptions of age discrimination would be lower in the United States. Methods. We analyzed data from two nationally representative studies of aging, the U.S. Health and Retirement Study (n = 4,818) and the English Longitudinal Study of Ageing (n = 7,478). Respondents aged 52 years and older who attributed any experiences of discrimination to their age were treated as cases of perceived age discrimination. We used multivariable logistic regression to estimate the odds ratios of experiencing perceived age discrimination in relation to selected sociodemographic factors. Results. Perceptions of age discrimination were significantly higher in England than the United States, with 34.8% of men and women in England reporting age discrimination compared with 29.1% in the United States. Associations between perceived age discrimination and older age and lower levels of household wealth were observed in both countries, but we found differences between England and the United States in the relationship between perceived age discrimination and education. Discussion. Our study revealed that levels of perceived age discrimination are lower in the United States than England and are less socially patterned. This suggests that differing social and political circumstances in the two countries may have an important role to play. PMID:26224759

Selective effects of emotion on the phenomenal characteristics of autobiographical memories.

PubMed

Schaefer, Alexandre; Philippot, Pierre

2005-02-01

The present study investigates the emotional determinants of the phenomenal characteristics of autobiographical memories. A total of 84 participants completed the Memory Characteristics Questionnaire (MCQ, Johnson, Foley, Suengas, & Raye, 1988) after retrieving and orally describing a negative, a positive, and a neutral autobiographical memory. In addition, self-report and physiological measures of emotional state at retrieval were recorded. Results suggest that recall of perceptual, sensory, and semantic elements is better for emotional memories than for neutral ones. This difference is not significant for contextual and temporal aspects, suggesting that emotional memories are more vivid but no more specific than are neutral ones. In addition, positive memories yielded higher MCQ ratings than did negative memories for sensory, temporal, and contextual aspects. Finally, correlations suggest a positive relation between emotional state at retrieval and level of phenomenal detail of retrieved memories. Results are interpreted in terms of multilevel models of emotion and of Conway and Pleydell-Pearce's (2000) model.

The competition of particle-vibration coupling and tensor interaction in spherical nuclei

NASA Astrophysics Data System (ADS)

Afanasjev, Anatoli; Litvinova, Elena

2014-09-01

The search for missing terms in the energy density functionals (EDF) is one of the leading directions in the development of nuclear density functional theory (DFT). Tensor force is one of possible candidates. However, despite extensive studies the questions about its effective strength and unambiguous signals still remain open. One of the main experimental benchmarks for the studies of tensor interaction is provided by the data on the single-particle states in the N = 82 and Z = 50 isotopes. The energy splittings of the proton h11 / 2 and g7 / 2 states in the Z = 50 isotopes and neutron 1i13 / 2 and 1h9 / 2 states in the N = 82 isotones are used in the definition of tensor force in the Skyrme DFT. However, in experiment these states are not ``mean-field'' states because of coupling with vibrations. Employing relativistic particle-vibration coupling (PVC) model we show that many features of these splittings can be reproduced when PVC is taken into account. This suggests the competition of PVC and tensor interaction and that tensor interaction should be weaker as compared with previous estimates. The search for missing terms in the energy density functionals (EDF) is one of the leading directions in the development of nuclear density functional theory (DFT). Tensor force is one of possible candidates. However, despite extensive studies the questions about its effective strength and unambiguous signals still remain open. One of the main experimental benchmarks for the studies of tensor interaction is provided by the data on the single-particle states in the N = 82 and Z = 50 isotopes. The energy splittings of the proton h11 / 2 and g7 / 2 states in the Z = 50 isotopes and neutron 1i13 / 2 and 1h9 / 2 states in the N = 82 isotones are used in the definition of tensor force in the Skyrme DFT. However, in experiment these states are not ``mean-field'' states because of coupling with vibrations. Employing relativistic particle-vibration coupling (PVC) model we show that many features of these splittings can be reproduced when PVC is taken into account. This suggests the competition of PVC and tensor interaction and that tensor interaction should be weaker as compared with previous estimates. This work has been supported by the U.S. Department of Energy under the Grant DE-FG02-07ER41459 and National Science Foundation Award PHY-1204486.

Cooperation in marine affairs: Evidence from the Gulf of Thailand

NASA Astrophysics Data System (ADS)

Harakunarak, Ampai

1998-12-01

This study argues that the evolving process of interstate cooperation based upon power interests could operate regardless of the formal or expressed will of governments to make binding agreements. The study developed a comprehensive model for interstate cooperation in which state interests were part of conditions for the mutual problem-solving process. The model was then tested against three marine issues in the Gulf of Thailand: offshore hydrocarbon development associated with maritime boundary delimitation, marine fisheries, and marine pollution. Literature review, newspapers and periodicals, on-line databases, and unstructured interviews were primary sources of data. The analysis found that consultation accounted for cooperative interaction among the realist Gulf of Thailand states. Evidence from three tested marine issues suggested that frequent contact and subsequent effects of a greater exchange of knowledge and information can at least stabilize relationships between the states. Informality and non-binding nature of the interactive process offered the states the needed flexibility in designing and implementing effective marine management in the Gulf of Thailand. The study discussed a modified realist framework and some implications for a future study of informal regimes and compliance with interstate agreements.

Exposure to fluoridated water and attention deficit hyperactivity disorder prevalence among children and adolescents in the United States: an ecological association.

PubMed

Malin, Ashley J; Till, Christine

2015-02-27

Epidemiological and animal-based studies have suggested that prenatal and postnatal fluoride exposure has adverse effects on neurodevelopment. The aim of this study was to examine the relationship between exposure to fluoridated water and Attention-Deficit Hyperactivity Disorder (ADHD) prevalence among children and adolescents in the United States. Data on ADHD prevalence among 4-17 year olds collected in 2003, 2007 and 2011 as part of the National Survey of Children's Health, and state water fluoridation prevalence from the Centers for Disease Control and Prevention (CDC) collected between 1992 and 2008 were utilized. State prevalence of artificial water fluoridation in 1992 significantly positively predicted state prevalence of ADHD in 2003, 2007 and 2011, even after controlling for socioeconomic status. A multivariate regression analysis showed that after socioeconomic status was controlled each 1% increase in artificial fluoridation prevalence in 1992 was associated with approximately 67,000 to 131,000 additional ADHD diagnoses from 2003 to 2011. Overall state water fluoridation prevalence (not distinguishing between fluoridation types) was also significantly positively correlated with state prevalence of ADHD for all but one year examined. Parents reported higher rates of medically-diagnosed ADHD in their children in states in which a greater proportion of people receive fluoridated water from public water supplies. The relationship between fluoride exposure and ADHD warrants future study.

Trait and State Positive Emotional Experience in Schizophrenia: A Meta-Analysis

PubMed Central

Yan, Chao; Cao, Yuan; Zhang, Yang; Song, Li-Ling; Cheung, Eric F. C.; Chan, Raymond C. K.

2012-01-01

Background Prior meta-analyses indicated that people with schizophrenia show impairment in trait hedonic capacity but retain their state hedonic experience (valence) in laboratory-based assessments. Little is known about what is the extent of differences for state positive emotional experience (especially arousal) between people with schizophrenia and healthy controls. It is also not clear whether negative symptoms and gender effect contribute to the variance of positive affect. Methods and Findings The current meta-analysis examined 21 studies assessing state arousal experience, 40 studies measuring state valence experience, and 47studies assessing trait hedonic capacity in schizophrenia. Patients with schizophrenia demonstrated significant impairment in trait hedonic capacity (Cohen’s d = 0.81). However, patients and controls did not statistically differ in state hedonic (valence) as well as exciting (arousal) experience to positive stimuli (Cohen’s d = −0.24 to 0.06). They also reported experiencing relatively robust state aversion and calmness to positive stimuli compared with controls (Cohen’s d = 0.75, 0.56, respectively). Negative symptoms and gender contributed to the variance of findings in positive affect, especially trait hedonic capacity in schizophrenia. Conclusions Our findings suggest that schizophrenia patients have no deficit in state positive emotional experience but impairment in “noncurrent” hedonic capacity, which may be mediated by negative symptoms and gender effect. PMID:22815785

Studies performed in the proper context suggest that antimicrobial use during swine and cattle production minimally impact antimicrobial resistance

USDA-ARS?s Scientific Manuscript database

In the United States (U.S.) it is estimated that food-animal production agriculture accounts for >70% of antimicrobial (AM) use leading to concerns that agricultural uses are the primary source of antimicrobial resistance (AMR). Many studies report AMR in food-animal production settings without comp...

Still Digitally Divided? An Assessment of Historically Black College and University Library Web Sites

ERIC Educational Resources Information Center

Hill, Renee Franklin

2012-01-01

Historically Black Colleges and Universities (HBCUs) are post-secondary institutions which, at one time, were considered to be particularly affected by the digital divide. Research study results have suggested the need for HBCUs to continuously increase campus technology. Guided by four research questions, this study examines the current state of…

Cesar Chavez--Grade Nine Model Curriculum and Resources.

ERIC Educational Resources Information Center

California State Dept. of Education, Sacramento.

This California state curriculum model for grade 9 about Cesar Chavez explains that grade 9 is an elective year for social studies courses and that one of the electives is a course about contemporary California. It suggests that students in schools offering this course could study the role of Chavez in 20th century California and his legacy. A…

Use of a Biographical Data Inventory to Identify Behavioral Correlates of Practicing Medical Technologists: An Exploratory Study

ERIC Educational Resources Information Center

Blume, Christiana S.

1976-01-01

A Biographical Data Inventory (BDI) and a standard final evaluation form were developed and administered to practicing medical technologists and senior year medical technology students at a State university. A correlation of .68 between scores reinforced findings of other studies, suggesting that BDI's are useful in advisement and selection of…

The Pollyanna Principle in Business Writing: Initial Results, Suggestions for Research.

ERIC Educational Resources Information Center

Hildebrandt, Herbert W.

A study was conducted to determine whether there was a linguistic correlation between a financially good year and a bad year as expressed in the annual reports of company presidents to their shareholders. Specifically the study tested the "Pollyanna Principle," which states (1) that regardless of whether the year was financially good or bad, the…

Making the Grade: School Achievement in Japan, Taiwan, and the United States.

ERIC Educational Resources Information Center

Stevenson, Harold W.

Recent calls for educational reform have focused on secondary schools, but results emerging from a cross-national study suggest that the reasons for American students' achievement problems lie not only in American schools but also in American homes. In the study, American, Taiwanese, and Japanese first and fifth graders were tested in reading and…

Channel Effects and Non-Verbal Properties of Media Messages: A State of the Art Review.

ERIC Educational Resources Information Center

McCain, Thomas A.; White, Sylvia

The purposes of this paper are to compile and describe the published empirical studies that have examined nonverbal visual production variables, to offer a critique of the lines of inquiry, and to suggest some areas for continued research. The studies are presented in two major sections: intravisual and intermedia. The intravisual section…

Movies and mood: an exploration of the critical variables related to mood states

Treesearch

Laura L. Payne; Tammie Shaw; Linda L. Caldwell

1998-01-01

The purpose of this study was to examine the relationship between movie viewing and mood, and to test the Pleasure Arousal Dominance (PAD) mood theory in a theater setting. The results of this exploratory study are presented here, challenging the PAD model, and providing suggestions for future research regarding the leisure and mood relationship.

Working Class Gender Relationships and Leisure in the United States, 1890-1920.

ERIC Educational Resources Information Center

Peiss, Kathy

Recent studies of the history of working-class leisure have rested on the conceptualization of leisure as both public and male. A study of the living conditions, recreational activities, and family budgets of white working-class New Yorkers between 1880 and 1920 suggests broad ways in which working women's leisure activities contributed to a…

A Study of the Perception Toward School Teachers and Self of the Return Migrant Student.

ERIC Educational Resources Information Center

Prewitt-Diaz, Joseph O.; Seilhamer, E. Stella

Previous research suggests that most Puerto Rican students who have spent some years in the United States and then returned to Puerto Rico generally experience cultural adjustment problems, language difficulties, low self-esteem, and identity crises. This study compared attitudes of Puerto Rican return migrant students (those who have returned to…

Teaching English in Indian Contexts: Toward a Pedagogic Model

ERIC Educational Resources Information Center

Kaushik, Sharda

2011-01-01

This study addresses an important problem in English pedagogy in one Outer Circle context, that of India, in that it investigates the match between the stated goals of English teaching in the policy documents and their implementation in actual curriculum, teaching and testing practices. In order to achieve a better match, the study suggests more…

What Determines Employment of Part-Time Faculty in Higher Education Institutions?

ERIC Educational Resources Information Center

Liu, Xiangmin; Zhang, Liang

2007-01-01

This study uses a cross-section national sample of four-year colleges and universities in the United States to examine the variation of part-time faculty employment. Results of this study suggest that higher educational institutions actively design and adopt contingent work arrangements to save on labor costs and to manage their resource…

Is Rest Really Rest? Resting State Functional Connectivity during Rest and Motor Task Paradigms.

PubMed

Jurkiewicz, Michael T; Crawley, Adrian P; Mikulis, David J

2018-04-18

Numerous studies have identified the default mode network (DMN) within the brain of healthy individuals, which has been attributed to the ongoing mental activity of the brain during the wakeful resting-state. While engaged during specific resting-state fMRI paradigms, it remains unclear as to whether traditional block-design simple movement fMRI experiments significantly influence the default mode network or other areas. Using blood-oxygen level dependent (BOLD) fMRI we characterized the pattern of functional connectivity in healthy subjects during a resting-state paradigm and compared this to the same resting-state analysis performed on motor task data residual time courses after regressing out the task paradigm. Using seed-voxel analysis to define the DMN, the executive control network (ECN), and sensorimotor, auditory and visual networks, the resting-state analysis of the residual time courses demonstrated reduced functional connectivity in the motor network and reduced connectivity between the insula and the ECN compared to the standard resting-state datasets. Overall, performance of simple self-directed motor tasks does little to change the resting-state functional connectivity across the brain, especially in non-motor areas. This would suggest that previously acquired fMRI studies incorporating simple block-design motor tasks could be mined retrospectively for assessment of the resting-state connectivity.

Barriers in detecting elder abuse among emergency medical technicians.

PubMed

Reingle Gonzalez, Jennifer M; Cannell, M Brad; Jetelina, Katelyn K; Radpour, Sepeadeh

2016-09-02

Elder abuse and neglect are highly under-reported in the United States. This may be partially attributed to low incidence of reporting among emergency medical technicians' (EMTs), despite state-mandated reporting of suspected elder abuse. Innovative solutions are needed to address under-reporting. The objective was to describe EMTs' experience detecting and reporting elder abuse. Qualitative data were collected from 11 EMTs and 12 Adult Protective Services (APS) caseworkers that participated in one of five semi-structured focus groups. Focus group data were iteratively coded by two coders. Findings suggest a number of barriers prevent EMTs from reporting elder abuse to APS. Participants suggested that limited training on elder abuse detection or reporting has been provided to them. EMTs suggested that training, creation of an automated reporting system or brief screening tool could be used to enhance EMT's ability to detect and communicate suspected cases of elder abuse to APS. Results from the present study suggest that EMTs may be uniquely situated to serve as elder abuse and neglect surveillance personnel. EMTs are eager to work with APS to address the under-reporting of elder abuse and neglect, but training is minimal and current reporting procedures are time-prohibitive given their primary role as emergency healthcare providers. Future studies should seek to translate these findings into practice by identifying specific indicators predictive of elder abuse and neglect for inclusion on an automated reporting instrument for EMTs.

The reduction of adult neurogenesis in depression impairs the retrieval of new as well as remote episodic memory

PubMed Central

Fang, Jing; Demic, Selver; Cheng, Sen

2018-01-01

Major depressive disorder (MDD) is associated with an impairment of episodic memory, but the mechanisms underlying this deficit remain unclear. Animal models of MDD find impaired adult neurogenesis (AN) in the dentate gyrus (DG), and AN in DG has been suggested to play a critical role in reducing the interference between overlapping memories through pattern separation. Here, we study the effect of reduced AN in MDD on the accuracy of episodic memory using computational modeling. We focus on how memory is affected when periods with a normal rate of AN (asymptomatic states) alternate with periods with a low rate (depressive episodes), which has never been studied before. Also, unlike previous models of adult neurogenesis, which consider memories as static patterns, we model episodic memory as sequences of neural activity patterns. In our model, AN adds additional random components to the memory patterns, which results in the decorrelation of similar patterns. Consistent with previous studies, higher rates of AN lead to higher memory accuracy in our model, which implies that memories stored in the depressive state are impaired. Intriguingly, our model makes the novel prediction that memories stored in an earlier asymptomatic state are also impaired by a later depressive episode. This retrograde effect exacerbates with increased duration of the depressive episode. Finally, pattern separation at the sensory processing stage does not improve, but rather worsens, the accuracy of episodic memory retrieval, suggesting an explanation for why AN is found in brain areas serving memory rather than sensory function. In conclusion, while cognitive retrieval biases might contribute to episodic memory deficits in MDD, our model suggests a mechanistic explanation that affects all episodic memories, regardless of emotional relevance. PMID:29879169

The reduction of adult neurogenesis in depression impairs the retrieval of new as well as remote episodic memory.

PubMed

Fang, Jing; Demic, Selver; Cheng, Sen

2018-01-01

Major depressive disorder (MDD) is associated with an impairment of episodic memory, but the mechanisms underlying this deficit remain unclear. Animal models of MDD find impaired adult neurogenesis (AN) in the dentate gyrus (DG), and AN in DG has been suggested to play a critical role in reducing the interference between overlapping memories through pattern separation. Here, we study the effect of reduced AN in MDD on the accuracy of episodic memory using computational modeling. We focus on how memory is affected when periods with a normal rate of AN (asymptomatic states) alternate with periods with a low rate (depressive episodes), which has never been studied before. Also, unlike previous models of adult neurogenesis, which consider memories as static patterns, we model episodic memory as sequences of neural activity patterns. In our model, AN adds additional random components to the memory patterns, which results in the decorrelation of similar patterns. Consistent with previous studies, higher rates of AN lead to higher memory accuracy in our model, which implies that memories stored in the depressive state are impaired. Intriguingly, our model makes the novel prediction that memories stored in an earlier asymptomatic state are also impaired by a later depressive episode. This retrograde effect exacerbates with increased duration of the depressive episode. Finally, pattern separation at the sensory processing stage does not improve, but rather worsens, the accuracy of episodic memory retrieval, suggesting an explanation for why AN is found in brain areas serving memory rather than sensory function. In conclusion, while cognitive retrieval biases might contribute to episodic memory deficits in MDD, our model suggests a mechanistic explanation that affects all episodic memories, regardless of emotional relevance.

Hypercoagulable states in patients with multiple myeloma can affect the thalidomide-associated venous thromboembolism.

PubMed

Talamo, Giampaolo P; Ibrahim, Sulfi; Claxton, David; Tricot, Guido J; Fink, Louis M; Zangari, Maurizio

2009-07-01

The therapeutic use of thalidomide in patients with multiple myeloma is often complicated by the development of venous thromboembolism. The objective of the present study was to identify hypercoagulable states associated with development of venous thromboembolism in thalidomide-treated multiple myeloma patients. We screened 49 consecutive multiple myeloma patients treated with thalidomide at baseline for hypercoagulability. With a median follow-up of 11 months, 10 of 49 multiple myeloma patients developed a thrombotic episode. Laboratory assays revealed an underlying abnormality in nine of the 10 patients; hypercoagulable screenings were normal in 36 of the 39 patients who did not develop venous thromboembolism (P < 0.0001). Our retrospective study results suggest that the multiple myeloma patients with thromboembolic complications during treatment with thalidomide have a frequent concomitant underlying thrombophilic state.

The effect of positive group psychotherapy on self-esteem and state anger among adolescents at Korean immigrant churches.

PubMed

Lee, Eun Jin

2015-04-01

The aim of the current study was to describe participants' experiences and examine the effects of group therapy on self-esteem and state anger among the adolescent children of immigrants in the US. A quasi-experimental design and qualitative and quantitative methods were used. Group therapy was conducted for 8weeks. Thirty-three adolescents took part in the study. Quantitative results revealed that group therapy improved self-esteem (t=2.222. p<.05) but not state anger. However, qualitative results suggested that group therapy helped improve interpersonal relationships and communication skills, the forgiveness of others, and the management of anger. Furthermore, group therapy utilizing positive psychology strategies improved self-esteem, interpersonal relationships, and communication skills. Copyright © 2014 Elsevier Inc. All rights reserved.

Angular studies of the magnetoresistance in the density wave state of the quasi-two-dimensional purple bronze KMo6O17

NASA Astrophysics Data System (ADS)

Guyot, H.; Dumas, J.; Kartsovnik, M. V.; Marcus, J.; Schlenker, C.; Sheikin, I.; Vignolles, D.

2007-07-01

The purple molybdenum bronze KMo6O17 is a quasi-two-dimensional compound which shows a Peierls transition towards a commensurate metallic charge density wave (CDW) state. High magnetic field measurements have revealed several transitions at low temperature and have provided an unusual phase diagram “temperature-magnetic field”. Angular studies of the interlayer magnetoresistance are now reported. The results suggest that the orbital coupling of the magnetic field to the CDW is the most likely mechanism for the field induced transitions. The angular dependence of the magnetoresistance is discussed on the basis of a warped quasi-cylindrical Fermi surface and provides information on the geometry of the Fermi surface in the low temperature density wave state.

Using a Theory-guided Learning Collaborative Model to Improve Implementation of EBPs in a State Children’s Mental Health System: A Pilot Study

PubMed Central

Nadeem, Erum; Weiss, Dara; Olin, S. Serene; Hoagwood, Kimberly E.; Horwitz, Sarah M.

2016-01-01

Learning collaboratives (LCs) are used widely to promote implementation of evidence-based practices (EBPs). However, there has been limited research on the effectiveness of LCs and models vary widely in their structure, focus and components. The goal of the present study was to develop and field test a theory-based LC model to augment a state-led, evidence-based training program for clinicians providing mental health services to children. Analysis of implementation outcomes contrasted LC sites to matched comparison sites that participated in the clinical training program alone. Results suggested that clinicians from sites participating in the LC were more highly engaged in the state-led clinical training program and were more likely to complete program requirements. PMID:27167744

Using a Theory-Guided Learning Collaborative Model to Improve Implementation of EBPs in a State Children's Mental Health System: A Pilot Study.

PubMed

Nadeem, Erum; Weiss, Dara; Olin, S Serene; Hoagwood, Kimberly E; Horwitz, Sarah M

2016-11-01

Learning collaboratives (LCs) are used widely to promote implementation of evidence-based practices. However, there has been limited research on the effectiveness of LCs and models vary widely in their structure, focus and components. The goal of the present study was to develop and field test a theory-based LC model to augment a state-led, evidence-based training program for clinicians providing mental health services to children. Analysis of implementation outcomes contrasted LC sites to matched comparison sites that participated in the clinical training program alone. Results suggested that clinicians from sites participating in the LC were more highly engaged in the state-led clinical training program and were more likely to complete program requirements.

Ethnobiology of snappers (Lutjanidae): target species and suggestions for management.

PubMed

Begossi, Alpina; Salivonchyk, Svetlana V; Araujo, Luciana G; Andreoli, Tainá B; Clauzet, Mariana; Martinelli, Claudia M; Ferreira, Allan G I; Oliveira, Luiz E C; Silvano, Renato A M

2011-03-16

In this study, we sought to investigate the biology (diet and reproduction) and ethnobiology (fishers knowledge and fishing spots used to catch snappers) of five species of snappers (Lutjanidae), including Lutjanus analis, Lutjanus synagris, Lutjanus vivanus, Ocyurus chrysurus, and Romboplites saliens at five sites along the northeast (Riacho Doce, Maceió in Alagoas State, and Porto do Sauípe, Entre Rios at Bahia State) and the southeast (SE) Brazilian coast (Paraty and Rio de Janeiro cities at Rio de Janeiro State, and Bertioga, at São Paulo State.).We collected 288 snappers and interviewed 86 fishermen. The stomach contents of each fish were examined and macroscopic gonad analysis was performed. Snappers are very important for the fisheries of NE Brazil, and our results indicated that some populations, such as mutton snapper (L. analis) and lane snapper (L. synagris), are being caught when they are too young, at early juvenile stages.Local knowledge has been shown to be a powerful tool for determining appropriate policies regarding management of target species, and artisanal fishermen can be included in management processes. Other suggestions for managing the fisheries are discussed, including proposals that could provide motivation for artisanal fishermen to participate in programs to conserve resources, such as co-management approaches that utilize local knowledge, the establishment of fishing seasons, and compensation of fishermen, through 'payment for environmental services'. These suggestions may enhance the participation of local artisanal fishermen in moving to a more realistic and less top-down management approach of the fish population.

The Normative Environment for Drug Use: Comparisons among American Indian and White Adolescents

PubMed Central

Dieterich, Sara E.; Swaim, Randall C.; Beauvais, Fred

2013-01-01

The present study examined the influence of descriptive norms, injunctive norms, perceived outcome expectancies, and ethnicity on marijuana and inhalant use among 2334 American Indian and white high school students who lived on or near reservations in the United States. Hierarchical multiple regression analyses were conducted with survey data collected during the 2009-2010 and 2010-2011 school years. Results suggest differences between ethnicities in the influence of the normative environment and outcome expectancies on both marijuana and inhalant use. Study limitations are noted, and future research is suggested. PMID:23768429

Teaching concepts of energy to nigerian children in the 7-11 year-old age range

NASA Astrophysics Data System (ADS)

Urevbu, Andrew O.

This study investigated the level of concept attainment of selected energy concepts for possible inclusion in the Nigerian (Bendel State) Primary Science Project (BPSP). Using an experimental design suggested by Solomon (1949), subjects were taught energy concepts at three levels - descriptive, comparative and quantitative. Results showed that levels of concept comprehension were hierarchical with a signficant decrease in achievement from descriptive to comparative and quantitative concepts. The results of this study suggest the need to describe levels of concept for particular grades in the elementary school curriculum and to match curriculum with thinking strategies of children.

Silymarin-Loaded Eudragit Nanoparticles: Formulation, Characterization, and Hepatoprotective and Toxicity Evaluation.

PubMed

El-Nahas, Amira E; Allam, Ahmed N; Abdelmonsif, Doaa A; El-Kamel, Amal H

2017-11-01

The objectives of this study were to formulate, characterize silymarin-loaded Eudragit nanoparticles (SNPs) and evaluate their hepatoprotective and cytotoxic effects after oral administration. SNPs were prepared by nanoprecipitation technique and were evaluated for particle size, entrapment efficiency, TEM, solid-state characterization, and in vitro drug release. The hepatoprotective activity was evaluated after oral administration of selected SNPs in carbon tetrachloride-intoxicated rats. Potential in vivo acute cytotoxicity study was also assessed. The selected SNPs contained 50 mg silymarin and 50 mg Eudragit polymers (1:1 w/w Eudragit RS 100 & Eudragit LS 100). Morphology of the selected SNPs (particle size of 84.70 nm and entrapment efficiency of 83.45% with 100% drug release after 12 h) revealed spherical and uniformly distributed nanoparticles. DSC and FT-IR studies suggested the presence of silymarin in an amorphous state and absence of chemical interaction. The hepatoprotective evaluation of the selected SNPs in CCl 4 -intoxicated rats revealed significant improvement in the activities of different biochemical parameters (P ≤ 0.01) compared to the marketed product. The histopathological studies suggested that the selected SNPs produced better hepatoprotective effect in CCl 4 -intoxicated rats compared with the commercially marketed product. Toxicity study revealed no evident toxic effect for blank or silymarin-loaded nanoparticles at the dose level of 50 mg/kg body weight. The obtained results suggested that the selected SNPs were safe and potentially offered enhancement in the pharmacological hepatoprotective properties of silymarin.

The Impact of State Laws Limiting Malpractice Damage Awards on Health Care Expenditures

PubMed Central

Hellinger, Fred J.; Encinosa, William E.

2006-01-01

Twenty-eight states have laws that limit payments in malpractice cases, and several studies indicate that these laws reduce the frequency and severity of malpractice claims and lower premiums. Moreover, proponents believe that such laws reduce health care expenditures by reducing the practice of defensive medicine. However, there is a dearth of empirical evidence about the impact of these laws on the cost of health care. We used multivariate models and relatively recent data to estimate the impact of state tort reform laws that directly limit malpractice damage payments on health care expenditures. Estimates from these models suggest that laws limiting malpractice payments lower state health care expenditures by between 3% and 4%. PMID:16809580

Ecological and social patterns of child dietary diversity in India: a population-based study.

PubMed

Gausman, Jewel; Perkins, Jessica M; Lee, Hwa-Young; Mejia-Guevara, Ivan; Nam, You-Seon; Lee, Jong-Koo; Oh, Juhwan; Subramanian, S V

2018-02-13

Dietary diversity (DD) measures dietary variation in children. Factors at the child, community, and state levels may be associated with poor child nutritional outcomes. However, few studies have examined the role of macro-level factors on child DD. This study seeks to 1) describe the distribution of child DD in India, 2) examine the variation in DD attributable to the child, community and state levels, and 3) explore the relationship between community socioeconomic context and child DD. Using nationally representative data from children aged 6-23 months in India, multilevel models were used to determine the associations between child DD and individual- and community-level factors. There was substantial variation in child DD score across demographic and socioeconomic characteristics. In an age and sex-only adjusted regression model, the largest portion of variation in child DD was attributable to the child level (75%) while the portions of variance attributable to the community-level and state level were similar to each other (15% and 11%). Including individual-level socioeconomic factors explained 35.6 percent of the total variation attributed to child DD at the community level and 24.8 percent of the total variation attributed to child DD at the state level. Finally, measures of community disadvantage were associated with child DD in when added to the fully adjusted model. This study suggests that both individual and contextual factors are associated with child DD. These results suggest that a population-based approach combined with a targeted intervention for at-risk children may be needed to improve child DD in India. Copyright © 2018 Elsevier Inc. All rights reserved.

Crystal structure and X-ray photoemission spectroscopic study of A{sub 2}LaMO{sub 6} [A=Ba, Ca; M=Nb, Ta

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dutta, Alo, E-mail: alo_dutta@yahoo.com; Saha, Sujoy; Kumari, Premlata

2015-09-15

The X-ray photoemission spectroscopic (XPS) study of the double perovskite oxides A{sub 2}LaMO{sub 6} [A=Ba, Ca; M=Nb, Ta] synthesized by the solid-state reaction technique has been carried out to investigate the nature of the chemical state of the constituent ions and the bonding between them. The Rietveld refinement of the X-ray diffraction patterns suggests the monoclinic crystal structure of all the materials at room temperature. The negative and positive chemical shifts of the core level XPS spectrum of O-1s and Nb-3d{sub 3/2}/Ta-4f{sub 5/2} respectively suggest the covalent bonding between Nb/Ta cations and O ion. The change of the bonding strengthmore » between the anion and the cations from one material to another has been analyzed. The vibrational property of the materials is investigated using the room temperature Raman spectra. A large covalency of Ta-based compound than Nb compound is confirmed from the relative shifting of the Raman modes of the materials. - Graphical abstract: Crystal structure of two perovskite oxides CLN and CLT is investigated. XPS study confirms the two different co-ordination environments of Ca and covalent bonding between B-site cations and O-ion. - Highlights: • Ordered perovskite structure obtained by Rietveld refinement of XRD patterns. • Study of nature of chemical bonding by X-ray photoemission spectroscopy. • Opposite chemical shift of d-states of Nb/Ta with respect to O. • Covalent bonding between d-states of Nb/Ta and O. • Relative Raman shifts of CLN and CLT substantiate the more covalent character of Ta than Nb.« less