Sensor fault diagnosis of aero-engine based on divided flight status

NASA Astrophysics Data System (ADS)

Zhao, Zhen; Zhang, Jun; Sun, Yigang; Liu, Zhexu

2017-11-01

Fault diagnosis and safety analysis of an aero-engine have attracted more and more attention in modern society, whose safety directly affects the flight safety of an aircraft. In this paper, the problem concerning sensor fault diagnosis is investigated for an aero-engine during the whole flight process. Considering that the aero-engine is always working in different status through the whole flight process, a flight status division-based sensor fault diagnosis method is presented to improve fault diagnosis precision for the aero-engine. First, aero-engine status is partitioned according to normal sensor data during the whole flight process through the clustering algorithm. Based on that, a diagnosis model is built for each status using the principal component analysis algorithm. Finally, the sensors are monitored using the built diagnosis models by identifying the aero-engine status. The simulation result illustrates the effectiveness of the proposed method.

Current status of atypical antipsychotics for the treatment of fibromyalgia.

PubMed

Rico-Villademoros, F; Calandre, E P; Slim, M

2014-06-01

The treatment of fibromyalgia requires pharmacological and nonpharmacological therapies. The pharmacological treatment of fibromyalgia is limited to a few drugs that have been demonstrated to be moderately effective in some but not all dimensions of the disease. Therefore, the search for new drugs to treat this condition is warranted. Atypical antipsychotics offered an attractive alternative because they had been shown to be active against several key symptoms of fibromyalgia. The results of open-label studies, however, appear to indicate that atypical antipsychotics are poorly tolerated in patients with fibromyalgia, and only quetiapine XR has been studied in randomized controlled trials. Quetiapine XR has demonstrated effectiveness in treating comorbid major depression, anxiety and sleep disturbance. However, in two randomized controlled trials, quetiapine XR was not differentiated from placebo and failed to demonstrate noninferiority to amitriptyline in terms of improving overall symptomatology. The effect of quetiapine XR on pain and its usefulness as part of a combination pharmacological regimen should be further evaluated. Overall, the use of quetiapine (initiated at a low dose and slowly titrated) in fibromyalgia should be limited to patients with comorbid major depression or patients who are currently receiving other treatments and have unresolved and disabling depressive and/or anxiety symptoms. Copyright 2014 Prous Science, S.A.U. or its licensors. All rights reserved.

76 FR 44891 - Monsanto Co.; Availability of Petition, Plant Pest Risk Assessment, and Environmental Assessment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-27

... Determination of Nonregulated Status for Corn Genetically Engineered for Drought Tolerance AGENCY: Animal and... nonregulated status for corn designated as MON 87460, which has been genetically engineered for drought... nonregulated status for corn designated as MON 87460, which has been genetically engineered for drought...

76 FR 5780 - Determination of Regulated Status of Alfalfa Genetically Engineered for Tolerance to the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-02

...] Determination of Regulated Status of Alfalfa Genetically Engineered for Tolerance to the Herbicide Glyphosate... for tolerance to the herbicide glyphosate based on APHIS' final environmental impact statement. FOR... regulated status of alfalfa genetically engineered for tolerance to the herbicide glyphosate based on an...

Drug repositioning summit: finding new routes to success.

PubMed

Campas, Clara

2009-03-01

The Third Annual Drug Repositioning Summit 2008 was held at the Hyatt Harborside Hotel in Boston, Massachusetts, October 6-7, and focused on new strategies for drug repositioning. The meeting, organized by The Cambridge Healthtech Institute, brought together a panel of speakers from the industry and the academia, who discussed and proposed new routes for success in drug repositioning based on their own experience in the field. This meeting report summarizes the most relevant presentations and issues discussed. Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved.

A report from the 20th United European Gastroenterology Week 2012 (October 20-24, 2012 - Amsterdam, the Netherlands).

PubMed

Escorsell, J

2012-12-01

This year saw the 20th anniversary of the first United European Gastroenterology Week (UEGW), the largest European conference focused on diseases of the stomach, bowel, esophagus, liver, pancreas and gallbladder. UEGW 2012, which was held in Amsterdam, the Netherlands, attracted over 14,000 delegates who discussed recent developments in the treatment of these diseases, including multidisciplinary care and the effect of obesity and alcohol on gastrointestinal and liver diseases. Copyright 2012 Prous Science, S.A.U. or its licensors. All rights reserved.

76 FR 39812 - Scotts Miracle-Gro Co.; Regulatory Status of Kentucky Bluegrass Genetically Engineered for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-07

...] Scotts Miracle-Gro Co.; Regulatory Status of Kentucky Bluegrass Genetically Engineered for Herbicide... engineered for herbicide tolerance without the use of plant pest components, does not meet the definition of... has been genetically engineered for herbicide tolerance, does not meet the definition of a regulated...

GTCBio's Precision Medicine Conference (July 7-8, 2016 - Boston, Massachusetts, USA).

PubMed

Cole, P

2016-09-01

GTCBio's Precision Medicine Conference met this year to outline the many steps forward that precision medicine and individualized genomics has made and the challenges it still faces in technological, modeling, and standards development, interoperability and compatibility advancements, and methods of economic and societal adoption. The conference was split into four sections, 'Overcoming Challenges in the Commercialization of Precision Medicine', 'Implementation of Precision Medicine: Strategies & Technologies', 'Integrating & Interpreting Personal Genomics, Big Data, & Bioinformatics' and 'Incentivizing Precision Medicine: Regulation & Reimbursement', with this report focusing on the final two subjects. Copyright 2016 Prous Science, S.A.U. or its licensors. All rights reserved.

Telemetry Standards, RCC Standard 106-17. Chapter 24. Message Formats

DTIC Science & Technology

2017-07-01

strength indicator TCP Transmission Control Protocol TE Traffic Engineering TAI International Atomic Time TLV Type-Length-Value TmNS Telemetry...to a specific radio link. TE Queue Status Report 10 This TLV is used by a radio to report Traffic Engineering (TE) queue levels for each of the 8...24.3.2.6 Traffic Engineering Queue Status Report TLV The TE Queue Status Report TLV shall be used to report the queue levels of the eight

A status report on the Energy Efficient Engine Project

NASA Technical Reports Server (NTRS)

Macioce, L. E.; Schaefer, J. W.; Saunders, N. T.

1980-01-01

The Energy Efficient Engine (E3) Project is directed at providing, by 1984, the advanced technologies which could be used for a new generation of fuel conservative turbofan engines. This paper summarizes the scope of the entire project and the current status of these efforts. Included is a description of the preliminary designs of the fully developed engines, the potential benefits of these advanced engines, and highlights of some of the component technology efforts conducted to date.

Tungsten fiber reinforced superalloys: A status review

NASA Technical Reports Server (NTRS)

Petrasek, D. W.; Signorelli, R. A.

1981-01-01

Improved performance of heat engines is largely dependent upon maximum cycle temperatures. Tungsten fiber reinforced superalloys (TFRS) are the first of a family of high temperature composites that offer the potential for significantly raising hot component operating temperatures and thus leading to improved heat engine performance. This status review of TFRS research emphasizes the promising property data developed to date, the status of TFRS composite airfoil fabrication technology, and the areas requiring more attention to assure their applicability to hot section components of aircraft gas turbine engines.

Committee on Earth Observation Satellites (CEOS) Systems Engineering Office (SEO). Ocean Surface Topography (OST) Workshop, Ruedesheim an Rhein, Germany. [CEOS SEO Status Report

NASA Technical Reports Server (NTRS)

Killough, Brian D., Jr.

2008-01-01

The CEOS Systems Engineering Office will present a 2007 status report of the CEOS constellation process, present a new systems engineering framework, and analysis results from the GEO Societal Benefit Area (SBA) assessment and the OST constellation requirements assessment.

40 CFR 85.515 - Exemption provisions for intermediate age vehicles/engines.

Code of Federal Regulations, 2013 CFR

2013-07-01

... age vehicles/engines. 85.515 Section 85.515 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...-ready status using an OBD scan tool appropriate for the OBD system in the vehicle/engine in question... have reset to a ready status, you must submit an OBD scan tool report showing that with the vehicle...

40 CFR 85.515 - Exemption provisions for intermediate age vehicles/engines.

Code of Federal Regulations, 2012 CFR

2012-07-01

... age vehicles/engines. 85.515 Section 85.515 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...-ready status using an OBD scan tool appropriate for the OBD system in the vehicle/engine in question... have reset to a ready status, you must submit an OBD scan tool report showing that with the vehicle...

40 CFR 85.515 - Exemption provisions for intermediate age vehicles/engines.

Code of Federal Regulations, 2011 CFR

2011-07-01

... age vehicles/engines. 85.515 Section 85.515 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...-ready status using an OBD scan tool appropriate for the OBD system in the vehicle/engine in question... have reset to a ready status, you must submit an OBD scan tool report showing that with the vehicle...

40 CFR 85.515 - Exemption provisions for intermediate age vehicles/engines.

Code of Federal Regulations, 2014 CFR

2014-07-01

... age vehicles/engines. 85.515 Section 85.515 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...-ready status using an OBD scan tool appropriate for the OBD system in the vehicle/engine in question... have reset to a ready status, you must submit an OBD scan tool report showing that with the vehicle...

76 FR 78232 - Monsanto Co.; Determination of Nonregulated Status for Soybean Genetically Engineered To Have a...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-16

... peer review of safety tests, and health effects of genetically modified organisms and glyphosate. APHIS...] Monsanto Co.; Determination of Nonregulated Status for Soybean Genetically Engineered To Have a Modified... that there is reason to believe are plant pests. Such genetically engineered organisms and products are...

A measure of productivity and innovation in the pharmaceutical industry 2011-2015.

PubMed

Harrison, R

2016-11-01

The pharmaceutical industry has faced enormous pressures over the last few decades. Declining revenues, increasing payer pressures, and a constantly changing regulatory landscape have forced all companies to identify processes to increase productivity and innovation. However, to date, no one agrees on precisely how to measure these attributes or how to interpret these results to understand the state of the industry. We propose new quantitative measures of productivity and innovation and use these to illustrate an industry that has in recent years become more innovative and productive after years of decline. Copyright 2016 Prous Science, S.A.U. or its licensors. All rights reserved.

Filgrastim for the treatment of hematopoietic acute radiation syndrome.

PubMed

Farese, A M; MacVittie, T J

2015-09-01

The U.S. Food and Drug Administration (FDA) recently approved Neupogen(®) (filgrastim) for the treatment of patients with radiation-induced myelosuppression following a radiological/nuclear incident. It is the first medical countermeasure currently approved by the FDA for this indication under the criteria of the FDA "animal rule". This article summarizes the consequences of high-dose radiation exposure, a description of the hematopoietic acute radiation syndrome (H-ARS), the use of hematopoietic growth factors in radiation accident victims and current available treatments for H-ARS with an emphasis on the use of Neupogen in this scenario. Copyright 2015 Prous Science, S.A.U. or its licensors. All rights reserved.

[Fungal (Candida) infections in the immunocompromised pediatric patient].

PubMed

Bruce Diemond, J; Lopez, C; Huerta Romano, F; Montiel Castillo, C

2008-11-01

Today, mycotic infections in immunocompromised patients are mainly caused by Candida spp. and Aspergillus spp. The patients most sensitive to these infections are those with some kind of cell-mediated immunity quantitative or qualitative alteration (i.e., blood-related cancer, primary or secondary neutropenia, immunosuppressive disease or therapy, etc.). Candida infection in the immunosupressed patient comprises a wide range of serious diseases such as candidemia, chronic disseminated candididasis, endocarditis, meningitis and endophthalmitis. Therefore, infection by Candida spp. is considered secondary to the technological and medical advances which extend the life of patients with chronic diseases. Copyright 2008 Prous Science, S.A.U. or its licensors. All rights reserved.

A report from the American Academy of Neurology 2014 Annual Meeting (April 26-May 3 - Philadelphia, Pennsylvania, USA).

PubMed

Rabasseda, X

2014-06-01

Not far from the Liberty Bell Hall and the historical parks of old Philadelphia, the Pennsylvania Convention Center hosted this year's American Academy of Neurology Annual Meeting for a full week of integrated science, symposium and general poster sessions. A great amount of research papers were presented and discussed during the meeting by attendees taking refuge from the downpour outside during at least 2 days. But the science was worth staying indoors to witness high-quality research, as summarized in this report. Copyright 2014 Prous Science, S.A.U. or its licensors. All rights reserved.

Thomson Reuters innovation award research brief: the use of patent analytics in measuring innovation in India.

PubMed

Stembridge, Bob

2009-09-01

There are six different factors that can be used to assess the inventiveness of an organization and to determine how efficiently they apply invention resources to innovate effectively. This research briefing describes the techniques used to measure certain aspects of patenting activity by Small and Medium-sized Enterprises (SMEs) headquartered in India. The techniques are used to identify the most innovative SMEs in India in order to determine the winners of the Innovation Award 2009 from Thomson Reuters, awarded at InfoVision 2009 in Bangalore. Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved.

32 CFR 700.846 - Status of logs.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Officers Afloat § 700.846 Status of logs. The deck log, the engineering log, the compass record, the bearing hooks, the engineer's bell book, and any records generated by automated data logging equipment...

40 CFR 85.520 - Exemption provisions for outside useful life vehicles/engines.

Code of Federal Regulations, 2012 CFR

2012-07-01

... useful life vehicles/engines. 85.520 Section 85.520 Protection of Environment ENVIRONMENTAL PROTECTION... monitors to not-ready status using an OBD scan tool appropriate for the OBD system in the vehicle/engine in... have reset to a ready status, you must submit an OBD scan tool report showing that with the vehicle...

40 CFR 85.520 - Exemption provisions for outside useful life vehicles/engines.

Code of Federal Regulations, 2014 CFR

2014-07-01

... useful life vehicles/engines. 85.520 Section 85.520 Protection of Environment ENVIRONMENTAL PROTECTION... monitors to not-ready status using an OBD scan tool appropriate for the OBD system in the vehicle/engine in... have reset to a ready status, you must submit an OBD scan tool report showing that with the vehicle...

Analysis of Office/Laboratory Staying Hour and Home Working Hour of Japanese Scientists and Engineers

NASA Astrophysics Data System (ADS)

Ejiri, A.

The second questionnaire for scientists and engineers was carried out in 2007, and status of Japanese scientists and engineers were analyzed and reported. A part of the data was reanalyzed from the viewpoint of work life balance. In particular, office/laboratory staying hour and home working hour were analyzed and dependences on various factors were investigated. It was found that these hours depend on gender, marital status, number of child, employment status and age. In addition, the total hours tend to be kept constant regardless of various factors.

Patient-Centred Innovations for Persons with Multimorbidity: funded evaluation protocol.

PubMed

Stewart, Moira; Fortin, Martin

2017-05-09

The high prevalence of multimorbidity necessitates rethinking of the health care system. The overarching goal of the Patient-Centred Innovations for Persons with Multimorbidity program is to build on existing structures and find and evaluate patient-centred innovations relevant to multimorbidity. We describe the protocol for a proposed multijurisdictional (Quebec and Ontario) concurrent triangulation mixed-methods study. In both provinces, a qualitative descriptive study will be used to explore innovations in patient-centred multimorbidity care. Two randomized controlled trials, 1 in either province, will evaluate the innovations in a wait-list-controlled design using patient-reported outcomes. An additional control group, matched on age, sex, enrolment/index date (± 3 mo) and propensity score, will be created with the use of health administrative data. Patients will be 18-80 years of age and will have 3 or more chronic conditions. The innovations will have elements of relevance to multimorbidity care, patient-centred partnerships and integration of care. The primary outcome measures will be 2 patient-reported outcomes: patient education and self-efficacy. Secondary outcomes will include patient-reported health status, quality of life, psychological distress and health behaviours, and costs of care. This protocol describes a mixed-method study in 2 jurisdictions. The studies will answer the questions of what innovations work and how they work for patients, health care professionals and policy-makers. Trial registration: ClinicalTrials.gov, no NCT02789800 (Quebec Trial), NCT02742597 (Ontario Trial). Copyright 2017, Joule Inc. or its licensors.

Cigarette smoking: health effects and control strategies.

PubMed

Alberg, Anthony J

2008-12-01

Active cigarette smoking causes a broad spectrum of diseases that extend to many different organ systems. Its numerous deleterious health effects, combined with the substantial prevalence of cigarette smoking, make it a major worldwide cause of death. Smoking contributes so heavily to the mortality burden because it is a major cause of vascular disease, cancer and chronic obstructive pulmonary disease. In addition to these diseases, cigarette smoking also causes other respiratory symptoms, adversely affects reproductive outcomes and is a cause of diminished health status. Furthermore, exposure to secondhand smoke is an established cause of coronary heart disease and lung cancer, as well as a host of other adverse health effects. Given that cigarette smoking is such a major threat to global public health, controlling the worldwide epidemic of cigarette smoking would lead to enormous public health benefits. Strategies to control cigarette smoking at the societal level include smoke-free workplace legislation, increasing cigarette taxes and regulating cigarette advertising. On the individual level, preventing the initiation of cigarette smoking among youths is the optimal strategy; in practice, discovering efficacious primary prevention interventions has proven challenging. During the past two decades, major advances have been made in extending the menu of options available to assist dependent smokers in successfully quitting smoking. Successfully combating cigarette smoking requires a broad-based commitment to smoking control from multiple stakeholders, along with a multifaceted strategy that addresses both societal and individual factors. Copyright 2008 Prous Science, S.A.U. or its licensors. All rights reserved.

2012 in review - part II: overcoming the obstacles in the pharma/biotech industry.

PubMed

Rabasseda, X; Dulsat, C; Navarro, D; Cruces, E; Graul, A I; Jago, C; Tracy, M

2013-02-01

As highlighted in the first part of this review published last month, the year 2012 saw the approval of a remarkable number of new drugs, and among the new drugs reaching the market, a significant proportion were orphan drugs developed for treating less prevalent diseases. These drugs are certainly not expected to become blockbusters, but are of high interest because of their efficacy in a narrow spectrum of patients. This trend aligns with the general tendency of staying away from fit-for-all blockbusters into personalized medicine as one of the strategies for overcoming the patent cliff that resulted in a long list of drugs going off patent and being approved as generics also during last year. The emerging scenario resulting from new developments in the form of new drugs and biosimilars and newly available generic medications paralleled by strategic movements within the pharmaceutical industry to reinforce their position in the market, as reflected by merger and acquisition deals accompanied by significant efforts into prioritization resulting in spin-off and split transactions, is reviewed in this second part. This paper includes a significant amount of data in tables for quick review and to profile the new strategic movements in drug pipelines. Further information, including details on mechanisms of action, current status, itemized pharmacology, pharmacokinetic and clinical trial research findings and updated information can be found in the proprietary databases Thomson Reuters Integrity(SM) and Thomson Reuters Cortellis™. Copyright 2013 Prous Science, S.A.U. or its licensors. All rights reserved.

Our Commitment to Reliable Health and Medical Information

MedlinePlus

... 000 visitors world-wide per day. HONcode Toolbar: search engine and checker of the certification status Automatically checks ... HONcode status when browsing health web sites. The search engine indexes only HONcode-certified sites. HONcodeHunt currently includes ...

The Status of Technology and Engineering Education in the United States: A Fourth Report of the Findings from the States (2011-12)

ERIC Educational Resources Information Center

Moye, Johnny J.; Dugger, William E., Jr.; Starkweather, Kendall N.

2012-01-01

Technology and engineering education continues to evolve as it becomes more apparent that students need this information to become more successful in college and careers. The International Technology and Engineering Educators Association (ITEEA ) has tracked the status of technology education in the United States in three separate studies over the…

AACR-NCI-EORTC - 27th International Symposium - Molecular Targets and Cancer Therapeutics (November 5-9, 2015 - Boston, Massachusetts, USA).

PubMed

Carceller, V

2015-11-01

The 27th joint meeting of the European Organization for Research and Treatment of Cancer, National Cancer Institute and the American Association of Cancer Research (EORTC-NCI-AACR) International Conference on Molecular Targets and Cancer Therapeutics was held this year in Boston. Approximately 3,000 international academics, scientists and pharmaceutical industry representatives discussed new discoveries in the field of molecular biology of cancer and presented the latest information on drug discovery, preclinical research, clinical research and target selection in oncology. This report summarizes data on advances in cancer drug discovery. Copyright 2015 Prous Science, S.A.U. or its licensors. All rights reserved.

MTR CONTROL ROOM WITH CONTROL CONSOLE AND STATUS READOUTS ALONG ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

MTR CONTROL ROOM WITH CONTROL CONSOLE AND STATUS READOUTS ALONG WALL. WORKERS MAKE ELECTRICAL AND OTHER CONNECTIONS. INL NEGATIVE NO. 4289. Unknown Photographer, 2/26/1952 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

40 CFR 79.4 - Requirement of registration.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) in a research, development, or test status; (ii) sold to automobile, engine, or component manufacturers for research, development, or test purposes; or (iii) sold to automobile manufacturers for factory... research, development, or test status or (ii) sold to petroleum, automobile, engine, or component...

40 CFR 79.4 - Requirement of registration.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) in a research, development, or test status; (ii) sold to automobile, engine, or component manufacturers for research, development, or test purposes; or (iii) sold to automobile manufacturers for factory... research, development, or test status or (ii) sold to petroleum, automobile, engine, or component...

40 CFR 79.4 - Requirement of registration.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) in a research, development, or test status; (ii) sold to automobile, engine, or component manufacturers for research, development, or test purposes; or (iii) sold to automobile manufacturers for factory... research, development, or test status or (ii) sold to petroleum, automobile, engine, or component...

40 CFR 79.4 - Requirement of registration.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) in a research, development, or test status; (ii) sold to automobile, engine, or component manufacturers for research, development, or test purposes; or (iii) sold to automobile manufacturers for factory... research, development, or test status or (ii) sold to petroleum, automobile, engine, or component...

40 CFR 79.4 - Requirement of registration.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) in a research, development, or test status; (ii) sold to automobile, engine, or component manufacturers for research, development, or test purposes; or (iii) sold to automobile manufacturers for factory... research, development, or test status or (ii) sold to petroleum, automobile, engine, or component...

Results and status of the NASA aircraft engine emission reduction technology programs

NASA Technical Reports Server (NTRS)

Jones, R. E.; Diehl, L. A.; Petrash, D. A.; Grobman, J.

1978-01-01

The results of an aircraft engine emission reduction study are reviewed in detail. The capability of combustor concepts to produce significantly lower levels of exhaust emissions than present production combustors was evaluated. The development status of each combustor concept is discussed relative to its potential for implementation in aircraft engines. Also, the ability of these combustor concepts to achieve proposed NME and NCE EPA standards is discussed.

Chemical Reaction Engineering: Current Status and Future Directions.

ERIC Educational Resources Information Center

Dudukovic, M. P.

1987-01-01

Describes Chemical Reaction Engineering (CRE) as the discipline that quantifies the interplay of transport phenomena and kinetics in relating reactor performance to operating conditions and input variables. Addresses the current status of CRE in both academic and industrial settings and outlines future trends. (TW)

Viewgraph description of Penn State's Propulsion Engineering Research Center: Activity highlights and future plans

NASA Technical Reports Server (NTRS)

Merkle, Charles L.

1991-01-01

Viewgraphs are presented that describe the progress and status of Penn State's Propulsion Engineering Research Center. The Center was established in Jul. 1988 by a grant from NASA's University Space Engineering Research Centers Program. After two and one-half years of operation, some 16 faculty are participating, and the Center is supporting 39 graduate students plus 18 undergraduates. In reviewing the Center's status, long-term plans and goals are reviewed and then the present status of the Center and the highlights and accomplishments of the past year are summarized. An overview of plans for the upcoming year are presented.

Status of Research in Biomedical Engineering 1968.

ERIC Educational Resources Information Center

National Inst. of General Medical Sciences (NIH), Bethesda, MD.

This status report is divided into eight sections. The first four represent the classical engineering or building aspects of bioengineering and deal with biomedical instrumentation, prosthetics, man-machine systems and computer and information systems. The next three sections are related to the scientific, intellectual and academic influence of…

Development status of the Vulcain engine

NASA Astrophysics Data System (ADS)

Gastal, J.; Eury, S.; Borromee, J.; Micewicz, J. B.

1993-06-01

The present account of the current status of the Ariane V launch vehicle's Vulcain first-stage cryofueled bipropellant engine gives attention to the Vulcain's overall configuration, as well as to its component designs, operational flowcharts, turbopump and combustion chamber performance verification trials, and program management responsibilities. Prospective development efforts currently envisioned are noted.

78 FR 13302 - Syngenta Biotechnology, Inc.; Determination of Nonregulated Status of Corn Genetically Engineered...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-27

...] Syngenta Biotechnology, Inc.; Determination of Nonregulated Status of Corn Genetically Engineered for... are advising the public of our determination that a corn line developed by the Syngenta Biotechnology... evaluation of data submitted by Syngenta Biotechnology, Inc., in its petition for a determination of...

Students' Changing Images of Engineering and Engineers. Research Brief

ERIC Educational Resources Information Center

Jocuns, Andrew; Stevens, Reed; Garrison, Lari; Amos, Daniel

2008-01-01

This study analyzes the images of engineers and engineering that students construct over the course of their undergraduate engineering educations. Students in their first year of study to become engineers knew very little about the work they would be doing as an engineer and their expectations were more specific, hopeful, and high status than…

Automotive Stirling Engine Development Program

NASA Technical Reports Server (NTRS)

Nightingale, N.; Ernst, W.; Richey, A.; Simetkosky, M.; Smith, G.; Rohdenburg, C.; Antonelli, M. (Editor)

1983-01-01

Program status and plans are discussed for component and technology development; reference engine system design, the upgraded Mod 1 engine; industry test and evaluation; and product assurance. Four current Mod 1 engines reached a total of 2523 operational hours, while two upgraded engines accumulated 166 hours.

US nuclear engineering education: Status and prospects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-01-01

This study, conducted under the auspices of the Energy Engineering Board of the National Research Council, examines the status of and outlook for nuclear engineering education in the United States. The study resulted from a widely felt concern about the downward trends in student enrollments in nuclear engineering, in both graduate and undergraduate programs. Concerns have also been expressed about the declining number of US university nuclear engineering departments and programs, the aging of their faculties, the appropriateness of their curricula and research funding for industry and government needs, the availability of scholarships and research funding, and the increasing ratiomore » of foreign to US graduate students. A fundamental issue is whether the supply of nuclear engineering graduates will be adequate for the future. Although such issues are more general, pertaining to all areas of US science and engineering education, they are especially acute for nuclear engineering education. 30 refs., 12 figs., 20 tabs.« less

Status of the NEXT Ion Engine Wear Test

NASA Technical Reports Server (NTRS)

Soulas, George C.; Domonkos, Matthew T.; Kamhawi, Hani; Patterson, Michael J.; Gardner, Michael M.

2003-01-01

The status of the NEXT 2000 hour wear test is presented. This test is being conducted with a 40 cm engineering model ion engine, designated EM1, at a beam current higher than listed on the NEXT throttle table. Pretest performance assessments demonstrated that EM1 satisfies all thruster performance requirements. As of 7/3/03, the ion engine has accumulated 406 hours of operation at a thruster input power of 6.9 kW. Overall ion engine performance, which includes thrust, thruster input power, specific impulse, and thrust efficiency, has been steady to date with no indications of performance degradation. Images of the downstream discharge cathode, neutralizer, and accelerator aperture surfaces have exhibited no significant erosion to date.

Citicoline for acute ischemic stroke in Mexican hospitals: a retrospective postmarketing analysis.

PubMed

Leon-Jimenez, C; Chiquete, E; Cantu, C; Miramontes-Saldana, M J; Andrade-Ramos, M A; Ruiz-Sandoval, J L

2010-06-01

Some neuroprotective agents have shown benefits in animal models, but disappointing results in humans. Citicoline is used in several countries as coadjuvant treatment in acute ischemic stroke (AIS) patients; however, there are no retrospective postmarketing surveillances on the experience of citicoline in Mexico. The aim of this study was to evaluate the correlation between citicoline exposure and functional outcome at discharge and at 30 and 90 days post-stroke, in a retrospective case-control design on systematic descriptive databases from three referral hospitals. Clinical records of 173 consecutively registered patients were analyzed, 86 of whom were treated with citicoline within the first 48 h after AIS and the remaining 87 were untreated, randomly selected controls matched for age (+/- 5 years), gender and NIHSS (+/- 1 point) at hospital admission. Pretreatment conditions were similar between groups. Compared with controls, exposure to citicoline was associated with a significantly lower 30-day mean and median modified Rankin score (in both, P < 0.05). After paired multivariate analyses (controlled for NIHSS, age, gender, hospital arrival in < 24 h, thrombolysis and comorbidities) citicoline was independently associated with a lower 90-day mortality risk (P = 0.047) and with fewer in-hospital complications (mainly infections and sepsis, P = 0.001). In this observational study, citicoline use was associated with a better functional status and lower rates of short-term mortality, possibly due to fewer in-hospital systemic complications. The putative benefits should be interpreted as clinical associations, since this is not a randomized, controlled clinical trial. Copyright 2010 Prous Science, S.A.U. or its licensors. All rights reserved.

U.S. Nuclear Engineering Education: Status and Prospects.

ERIC Educational Resources Information Center

National Academy of Sciences - National Research Council, Washington, DC. Commission on Engineering and Technical Systems.

This study examines the status of and outlook for nuclear engineering (NE) in the United States. The study resulted from a concern about the downward trends in student enrollments in NE, in both graduate and undergraduate programs. Concerns have also been expressed about the declining number of U.S. university NE departments and programs, the…

PROCESS WATER BUILDING, TRA605. CONTROL PANEL SUPPLIES STATUS INDICATORS. CARD ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PROCESS WATER BUILDING, TRA-605. CONTROL PANEL SUPPLIES STATUS INDICATORS. CARD IN LOWER RIGHT WAS INSERTED BY INL PHOTOGRAPHER TO COVER AN OBSOLETE SECURITY RESTRICTION ON ORIGINAL NEGATIVE. INL NEGATIVE NO. 4219. Unknown Photographer, 2/13/1952 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

Pharma Pricing & Market Access Europe 2016--Health Network Communications' Tenth Annual Conference (February 23-25, 2016--London, UK).

PubMed

D'Souza, P

2016-03-01

Tighter national budgets and escalating drug prices continue to present challenges for pharmaceutical market access strategies and societal cost of care. As pharmaceutical companies and medical governmental advisory organizations enter tougher negotiations, hospital trusts and other dispensary firms face barriers to receiving the best medical treatment, and as a result patient access is limited. The 2016 HealthNetwork Communications' Pharma Pricing & Market Access Europe meeting brought together pharmaceutical, medical governmental advisory and stakeholders and market access/pricing consultants, to encourage discussions and negotiations into how to improve the drug pricing system and consequential market access strategies while achieving the respective reimbursement and affordability objectives. Copyright 2016 Prous Science, S.A.U. or its licensors. All rights reserved.

A report from the 29th Annual Congress of the European Association of Urology (April 11-15 - Stockholm, Sweden).

PubMed

Rabasseda, X

2014-05-01

The annual congress of the European Association of Urology in Stockholm was packed with mixed poster/oral sessions wherein innovative clinical and preclinical research aimed at improving the care of patients with urinary tract diseases was reported and open for discussion. Not everything that was reported during the meeting can be captured in a single report, but the following text will guide readers through the most significant new findings directly related with pharmacotherapy for overactive bladder, urinary tract cancer and other common medical conditions that endanger the quality of life and life expectancy of many patients worldwide. Copyright 2014 Prous Science, S.A.U. or its licensors. All rights reserved.

Business of biosimilars - 14th annual conference (October 15-17, 2013 - Boston, Massachusetts, USA).

PubMed

Bourgoin, A

2013-12-01

Competition in the biological market offers a new set of opportunities and challenges within the healthcare industry. Biosimilars, like generic small-molecule drugs, can provide cost savings and increase patient access, while also promoting innovation. While large molecule manufacturers face many challenges unique to complex therapeutics, it is becoming clear that the commercialization of biosimilars shares many of the same hurdles as the generics market. The 14th Annual Business of Biosimilars Conference provided quality presentations from industry leaders regarding many commercial considerations for stakeholders interested in entering the biosimilars market. Opportunities to network with industry experts were offered, with over 120 attendees. Copyright 2013 Prous Science, S.A.U. or its licensors. All rights reserved.

Cachexia.

PubMed

Graul, A I; Stringer, M; Sorbera, L

2016-09-01

Cachexia is a multiorgan, multifactorial and often irreversible wasting syndrome associated with cancer and other serious, chronic illnesses including AIDS, chronic heart failure, chronic kidney disease and chronic obstructive pulmonary disease. Treatment of the patient with cachexia is currently targeted to correcting the two underlying features of the condition: anorexia and metabolic disturbances. Greater understanding of the mechanisms behind cachexia and muscle wasting have led to new therapeutic possibilities, however. Several classes of drugs are under active development for cachexia including drugs acting on hormone receptors or cytokine receptors, myostatin/activin pathway antagonists, beta-adrenoceptor agonists and cannabinoids. This review will cover the pathophysiology, epidemiology, diagnosis, treatment, drug candidates under active development and targets for therapeutic intervention of cachexia. Copyright 2016 Prous Science, S.A.U. or its licensors. All rights reserved.

Fiber reinforced superalloys

NASA Technical Reports Server (NTRS)

Petrasek, Donald W.; Signorelli, Robert A.; Caulfield, Thomas; Tien, John K.

1987-01-01

Improved performance of heat engines is largely dependent upon maximum cycle temperatures. Tungsten fiber reinforced superalloys (TFRS) are the first of a family of high temperature composites that offer the potential for significantly raising hot component operating temperatures and thus leading to improved heat engine performance. This status review of TFRS research emphasizes the promising property data developed to date, the status of TFRS composite airfoil fabrication technology, and the areas requiring more attention to assure their applicability to hot section components of aircraft gas turbine engines.

Review of status and potential of tungsten-wire: Superalloy composites for advanced gas turbine engine blades

NASA Technical Reports Server (NTRS)

Signorelli, R. A.

1972-01-01

The current status of development of refractory-wire-superalloy composites and the potential for their application to turbine blades in land-based power generation and advanced aircraft engines are reviewed. The data indicate that refractory-wire-superalloy composites have application as turbine blades at temperatures of 2200 F and above.

Recognizing the 150th anniversary of the founding of the Brotherhood of Locomotive Engineers and Trainmen, and congratulating the members and officers of the Brotherhood of Locomotive Engineers and Trainmen for the union's many achievements.

THOMAS, 113th Congress

Rep. Walz, Timothy J. [D-MN-1

2013-05-08

House - 05/09/2013 Referred to the Subcommittee on Railroads, Pipelines, and Hazardous Materials. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Status of the Combined Cycle Engine Rig

NASA Technical Reports Server (NTRS)

Saunders, Dave; Slater, John; Dippold, Vance

2009-01-01

Status for the past year is provided of the turbine-based Combined-Cycle Engine (CCE) Rig for the hypersonic project. As part of the first stage propulsion of a two-stage-to-orbit vehicle concept, this engine rig is designed with a common inlet that supplies flow to a turbine engine and a dual-mode ramjet / scramjet engine in an over/under configuration. At Mach 4 the inlet has variable geometry to switch the airflow from the turbine to the ramjet / scramjet engine. This process is known as inlet mode-transition. In addition to investigating inlet aspects of mode transition, the rig will allow testing of turbine and scramjet systems later in the test series. Fully closing the splitter cowl "cocoons" the turbine engine and increases airflow to the scramjet duct. The CCE Rig will be a testbed to investigate integrated propulsion system and controls technology objectives. Four phases of testing are planned to 1) characterize the dual inlet database, 2) collect inlet dynamics using system identification techniques, 3) implement an inlet control to demonstrate mode-transition scenarios and 4) demonstrate integrated inlet/turbine engine operation through mode-transition. Status of the test planning and preparation activities is summarized with background on the inlet design and small-scale testing, analytical CFD predictions and some details of the large-scale hardware. The final stages of fabrication are underway.

Engineering Education and Its Rewards in the United States and Japan.

ERIC Educational Resources Information Center

Kinmonth, Earl H.

1986-01-01

Contrary to misinformation circulating in the United States, the United States has more engineers absolutely and relatively than does Japan; and U.S. engineers have higher relative income and status than their Japanese counterparts. Compares U.S. and Japanese enrollments in engineering education, curriculum content, engineers' earnings relative to…

Engineering in K-12 Education: Understanding the Status and Improving the Prospects

ERIC Educational Resources Information Center

Katehi, Linda, Ed.; Pearson, Greg, Ed.; Feder, Michael, Ed.

2009-01-01

Engineering education in K-12 classrooms is a small but growing phenomenon that may have implications for engineering and also for the other STEM subjects--science, technology, and mathematics. Specifically, engineering education may improve student learning and achievement in science and mathematics, increase awareness of engineering and the work…

Automobile Engine Control Parameters Study : Volume 1. Summary and Status of Domestic Engine Control Practice

DOT National Transportation Integrated Search

1977-02-01

This report contains the results of a study to evaluate automobile engine control parameters and their effects on vehicle fuel economy and emissions. Volume I presents detailed technical information on the engine control practices used by selected do...

US Nuclear Engineering Education: Status and prospects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-01-01

This study, conducted under the auspices of the Energy Engineering Board of the National Research Council, examines the status of and outlook for nuclear engineering education in the United States. The study, as described in this report resulted from a widely felt concern about the downward trends in student enrollments in nuclear engineering, in both graduate and undergraduate programs. Concerns have also been expressed about the declining number of US university nuclear engineering departments and programs, the ageing of their faculties, the appropriateness of their curricula and research funding for industry and government needs, the availability of scholarships and researchmore » funding, and the increasing ratio of foreign to US graduate students. A fundamental issue is whether the supply of nuclear engineering graduates will be adequate for the future. Although such issues are more general, pertaining to all areas of US science and engineering education, they are especially acute for nuclear engineering education. 30 refs., 24 figs., 49 tabs.« less

Status on the Verification of Combustion Stability for the J-2X Engine Thrust Chamber Assembly

NASA Technical Reports Server (NTRS)

Casiano, Matthew; Hinerman, Tim; Kenny, R. Jeremy; Hulka, Jim; Barnett, Greg; Dodd, Fred; Martin, Tom

2013-01-01

Development is underway of the J -2X engine, a liquid oxygen/liquid hydrogen rocket engine for use on the Space Launch System. The Engine E10001 began hot fire testing in June 2011 and testing will continue with subsequent engines. The J -2X engine main combustion chamber contains both acoustic cavities and baffles. These stability aids are intended to dampen the acoustics in the main combustion chamber. Verification of the engine thrust chamber stability is determined primarily by examining experimental data using a dynamic stability rating technique; however, additional requirements were included to guard against any spontaneous instability or rough combustion. Startup and shutdown chug oscillations are also characterized for this engine. This paper details the stability requirements and verification including low and high frequency dynamics, a discussion on sensor selection and sensor port dynamics, and the process developed to assess combustion stability. A status on the stability results is also provided and discussed.

Automotive Stirling engine development program - Overview and status report

NASA Technical Reports Server (NTRS)

Nightingale, N. P.

1983-01-01

The current status of the automotive-Stirling-engine development program being undertaken by DOE and NASA Lewis is reviewed. The program goals and the reference-engine design are explained, and the modifications introduced to improve performance and lower manufacturing costs are discussed and illustrated, including part-power optimization; increased operating temperature (from 720 to 820 C); 45.4-kg weight reduction; elimination of Co and reduction of Cr used; and improved seals, ceramic components, and high-temperature alloys. The test program, some difficulties encountered, and results after 2042 h are summarized.

40 CFR 1068.31 - What provisions apply to nonroad or stationary engines that change their status?

Code of Federal Regulations, 2010 CFR

2010-07-01

... nonroad application is subsequently used in an application other than a nonroad application, or when an engine previously used in a stationary application (i.e., an engine that was not used as a nonroad engine... stationary engine becomes a new nonroad engine if— (1) It is used in an application that meets the criteria...

77 FR 41366 - Syngenta Biotechnology, Inc.; Availability of Petition, Plant Pest Risk Assessment, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... engineered organisms and products. We are soliciting comments on whether this genetically engineered corn is... pests. Such genetically engineered organisms and products are considered ``regulated articles.'' The... Assessment for Determination of Nonregulated Status of Corn Genetically Engineered for Insect Resistance...

A Cross-Sectional Study of Engineering Students' Self-Efficacy by Gender, Ethnicity, Year, and Transfer Status

ERIC Educational Resources Information Center

Concannon, James P.; Barrow, Lloyd H.

2009-01-01

This is a cross-sectional study of 519 undergraduate engineering majors' self-efficacy beliefs at a large, research extensive, Midwestern university. Engineering self-efficacy is an individual's belief in his or her ability to successfully negotiate the academic hurdles of the engineering program. Engineering self-efficacy was obtained from four…

Examining the Relationship between Technology & Engineering Instruction and Technology & Engineering Literacy in K-8 Education

ERIC Educational Resources Information Center

Mitchell, Tamarra L.

2017-01-01

The purpose of this study was to examine the relationship between technology and engineering instruction and technology and engineering literacy in grades K-8. The factors identified and used for the purpose of this study were gender, socioeconomic status, race/ethnicity, and important modes of technology and engineering instruction. These factors…

A report from the American college of rheumatology/association of rheumatology health professionals (ACR/ARHP) - 2012 annual meeting (November 9-14, 2012 - Washington, D.C., USA).

PubMed

Croasdell, G

2013-02-01

The annual meeting of the American College of Rheumatology (ACR), jointly held with the Association of Rheumatology Health Professionals (ARHP), brought together attendees focused on all aspects of rheumatology, including researchers looking into treatment options and various services around the care of rheumatologic conditions. As well as networking opportunities at the meeting, there were a wide range of symposia and posters available covering various conditions and levels of research. There were also educational and meet-the-professor sessions. This report will cover a selection of interesting talks from poster and oral sessions on the latest preclinical and clinical research. Copyright 2013 Prous Science, S.A.U. or its licensors. All rights reserved.

The 32nd Annual J.P. Morgan Healthcare Conference (January 13-16, 2014 - San Francisco, California, USA): Auxilium Pharmaceuticals.

PubMed

Watt, J

2014-03-01

CEO and President Adrian Adams described Auxilium Pharmaceuticals as "the same as a Big Pharma company, only smaller." This 'specialty biopharmaceutical company' has transformed itself in the last 6 to 9 months to become the "leading men's healthcare franchise with a broad and diverse product portfolio." All of this has led to a very busy 2013, which began with the USD 600 million acquisition (Q2) and integration of Actient Pharmaceuticals, the licensing of avanafil (Stendra™) for erectile dysfunction and ended with the approval of collagenase Clostridium histolyticum (Xiaflex®) in Peyronie's disease. From a portfolio of 2 products at the beginning of 2013, Auxilium ended the year with 12. Copyright 2014 Prous Science, S.A.U. or its licensors. All rights reserved.

Spinosad for the treatment of head lice infestations.

PubMed

Villegas, S C

2012-09-01

Head lice infestations continue to be an issue in today's society, with an increase in economic cost and resistance. Spinosad 0.9% topical suspension was recently introduced in the U.S. market as a novel agent with both pediculicidal and ovicidal activity, approved in children 4 years of age and older for the treatment of head lice infestations. In clinical trials, it has demonstrated effectiveness against head lice with permethrin resistance. In two clinical trials comparing spinosad to permethrin, efficacy was observed in the spinosad-treated groups at 84.6% and 86.7%, respectively, when compared to the permethrin-treated groups (respective values of 44.9% and 42.9%; P < 0.001). Overall, spinosad was well tolerated in clinical trials. Copyright 2012 Prous Science, S.A.U. or its licensors. All rights reserved.

Gateways to clinical trials.

PubMed

Tomillero, A; Moral, M A

2009-10-01

[Methoxy-11c]PD-153035; Afamelanotide, Agalsidase beta, Alemtuzumab, Alkaline phosphatase, Amlodipine, Anecortave acetate, Apixaban, Aripiprazole, Atomoxetine hydrochloride; Bevacizumab, Bortezomib, Bosentan, Botulinum toxin type B, Brimonidine tartrate/timolol maleate, Brivudine; Canakinumab, Cetuximab, Chlorotoxin, Cinaciguat; Dapagliflozin, Decitabine, Duloxetine hydrochloride; Elagolix sodium, Eplerenone, Eritoran tetrasodium, Escitalopram oxalate, Etoricoxib, Ezetimibe; Fospropofol disodium; G-207, Gabapentin enacarbil, Gefitinib, Golimumab; Human plasmin; Inotuzumab ozogamicin, Insulin glargine, Insulin glulisine, Istaroxime, Ixabepilone; KLH; Levodopa/carbidopa/entacapone; Miglustat, Mitumprotimut-T, MP-470; Oblimersen sodium, Olmesartan medoxomil; P53-SLP, PAN-811, Patupilone, Pazopanib hydrochloride, PC-515, Peginterferon alfa-2a, Pegylated arginine deiminase 20000, Pemetrexed disodium, Plitidepsin, Pregabalin; Rasagiline mesilate, Rotigotine; SCH-697243, Sirolimus-eluting stent, Sumatriptan succinate/naproxen sodium, Sunitinib malate; Tadalafil, Tapentadol hydrochloride, TMC-207; V-211, Valganciclovir hydrochloride; Zolpidem tartrate. Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved.

Apatinib: a promising oral antiangiogenic agent in the treatment of multiple solid tumors.

PubMed

Scott, A J; Messersmith, W A; Jimeno, A

2015-04-01

Aberrant proangiogenic pathways have long been implicated in tumorigenesis and metastasis. Antiangiogenic therapies have shown efficacy in the treatment of a variety of solid tumors including lung, breast, colon, glioblastomas, and other solid tumor types. Apatinib, a small-molecule inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2), is an orally bioavailable agent currently being studied in multiple tumor types. Apatinib has shown a survival benefit in gastric cancer in a phase III trial and non-small cell lung cancer in a phase II trial. With a favorable side effect profile and improved outcomes, apatinib has demonstrated a substantial potential to augment therapeutic options in a variety of tumor types. Copyright 2015 Prous Science, S.A.U. or its licensors. All rights reserved.

Valbenazine for the treatment of tardive dyskinesia.

PubMed

Barquero, N

2016-12-01

Valbenazine (NBI-98854, Ingrezza) is a highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor that modulates dopamine release during nerve communication. The pharmacological target VMAT2 may play an important role in the treatment of tardive dyskinesia (TD), an iatrogenic condition associated with the administration of antipsychotic medication for long periods and characterized by rapid, repetitive, stereotypic, involuntary movements of the face and extremities. There are currently no Food and Drug Administration (FDA)-approved drugs for the treatment of TD. Results of clinical trials have shown a distinctive improvement in TD symptoms during valbenazine administration and a new drug application submitted to the FDA in August 2016 is undergoing priority review with a decision expected in April 2017. Copyright 2016 Prous Science, S.A.U. or its licensors. All rights reserved.

A report from the 2011 annual meeting of the american academy of Allergy, Asthma and Immunology (March 18-22, 2011 - San Francisco, California, USA).

PubMed

Rabasseda, X

2011-04-01

San Francisco held this year's annual meeting of the American Academy of Allergy, Asthma and Immunology at the Moscone Center, where oral and poster sessions, educational courses and informal discussions called to the mind of attendees important news on a wide range of topics, including the main subject of this report: therapies for immune-based disorders as common as asthma or allergic rhinoconjunctivitis. A lot of important news from clinical and preclinical studies was disclosed to specialists attending this year's meeting. Most of the new research directly related to therapy for immunological diseases and disorders is summarized in the following report. 2011 Prous Science, S.A.U. or its licensors. All rights reserved.

Anxiolytic-like effect of Aronia melanocarpa fruit juice in rats.

PubMed

Valcheva-Kuzmanova, S; Zhelyazkova-Savova, M

2009-12-01

The main biologically active constituents of Aronia melanocarpa fruit juice (AMFJ) are polyphenolics, amongst them flavonoids, mainly anthocyanins. The aim of the present study was to investigate the effects of AMFJ (5 and 10 mL/kg) on anxiety using the social interaction test, on locomotor activity in the open field test and on working memory in the object recognition test in rats. AMFJ showed an anxiolytic-like effect which was demonstrated by a dose-dependent increase in the time of active social contacts between the test partners. The effects of both AMFJ doses were comparable to the effect of diazepam (1 mg/kg). AMFJ neither changed significantly horizontal and vertical locomotor activity, nor did it adversely affect working memory. Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved.

76 FR 8707 - Syngenta Seeds, Inc.; Determination of Nonregulated Status for Corn Genetically Engineered To...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-15

... for Corn Genetically Engineered To Produce an Enzyme That Facilitates Ethanol Production AGENCY... event 3272, which has been genetically engineered to produce a microbial enzyme that facilitates ethanol... transformation event 3272, which has been genetically engineered to produce a microbial enzyme that facilitates...

The Impact of Design-Based STEM Integration Curricula on Student Achievement in Engineering, Science, and Mathematics

NASA Astrophysics Data System (ADS)

Selcen Guzey, S.; Harwell, Michael; Moreno, Mario; Peralta, Yadira; Moore, Tamara J.

2017-04-01

The new science education reform documents call for integration of engineering into K-12 science classes. Engineering design and practices are new to most science teachers, meaning that implementing effective engineering instruction is likely to be challenging. This quasi-experimental study explored the influence of teacher-developed, engineering design-based science curriculum units on learning and achievement among grade 4-8 students of different races, gender, special education status, and limited English proficiency (LEP) status. Treatment and control students ( n = 4450) completed pretest and posttest assessments in science, engineering, and mathematics as well as a state-mandated mathematics test. Single-level regression results for science outcomes favored the treatment for one science assessment (physical science, heat transfer), but multilevel analyses showed no significant treatment effect. We also found that engineering integration had different effects across race and gender and that teacher gender can reduce or exacerbate the gap in engineering achievement for student subgroups depending on the outcome. Other teacher factors such as the quality of engineering-focused science units and engineering instruction were predictive of student achievement in engineering. Implications for practice are discussed.

40 CFR 63.526 - Monitoring requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... vent. (D) Design analysis based on accepted chemical engineering principles, measurable process.... (i) For the purpose of determining de minimis status for emission points, engineering assessment may... operating conditions expected to yield the highest flow rate and concentration. Engineering assessment...

40 CFR 63.526 - Monitoring requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... vent. (D) Design analysis based on accepted chemical engineering principles, measurable process.... (i) For the purpose of determining de minimis status for emission points, engineering assessment may... operating conditions expected to yield the highest flow rate and concentration. Engineering assessment...

40 CFR 63.526 - Monitoring requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... vent. (D) Design analysis based on accepted chemical engineering principles, measurable process.... (i) For the purpose of determining de minimis status for emission points, engineering assessment may... operating conditions expected to yield the highest flow rate and concentration. Engineering assessment...

Development Status of Reusable Rocket Engine

NASA Astrophysics Data System (ADS)

Yoshida, Makoto; Takada, Satoshi; Naruo, Yoshihiro; Niu, Kenichi

A 30-kN rocket engine, a pilot engine, is being developed in Japan. Development of this pilot engine has been initiated in relation to a reusable sounding rocket, which is also being developed in Japan. This rocket takes off vertically, reaches an altitude of 100 km, lands vertically at the launch site, and is launched again within several days. Due to advantage of reusability, successful development of this rocket will mean that observation missions can be carried out more frequently and economically. In order to realize this rocket concept, the engines installed on the rocket should be characterized by reusability, long life, deep throttling and health monitoring, features which have not yet been established in Japanese rocket engines. To solve the engineering factors entitled by those features, a new design methodology, advanced engine simulations and engineering testing are being focused on in the pilot engine development stage. Especially in engineering testing, limit condition data is acquired to facilitate development of new diagnostic techniques, which can be applied by utilizing the mobility of small-size hardware. In this paper, the development status of the pilot engine is described, including fundamental design and engineering tests of the turbopump bearing and seal, turbine rig, injector and combustion chamber, and operation and maintenance concepts for one hundred flights by a reusable rocket are examined.

Handbook of data on selected engine components for solar thermal applications

NASA Technical Reports Server (NTRS)

1979-01-01

A data base on developed and commercially available power conversion system components for Rankine and Brayton cycle engines, which have potential application to solar thermal power-generating systems is presented. The status of the Stirling engine is discussed.

40 CFR 63.526 - Monitoring requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

.... (D) Design analysis based on accepted chemical engineering principles, measurable process parameters... purpose of determining de minimis status for emission points, engineering assessment may be used to... expected to yield the highest flow rate and concentration. Engineering assessment includes, but is not...

40 CFR 63.526 - Monitoring requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... (D) Design analysis based on accepted chemical engineering principles, measurable process parameters... purpose of determining de minimis status for emission points, engineering assessment may be used to... expected to yield the highest flow rate and concentration. Engineering assessment includes, but is not...

Development status of rotary engine at Toyo Kogyo. [for general aviation aircraft

NASA Technical Reports Server (NTRS)

Yamamoto, K.

1978-01-01

Progress in the development of rotary engines which use a thermal reactor as the primary part of the exhaust emission control system is reviewed. Possibilities of further improvements in fuel economy of future rotary engines are indicated.

ISTAR: Project Status and Ground Test Engine Design

NASA Technical Reports Server (NTRS)

Quinn, Jason Eugene

2003-01-01

Review of the current technical and programmatic status of the Integrated System Test of an Airbreathing Rocket (ISTAR) project. November 2002 completed Phase 1 of this project: which worked the conceptual design of the X-43B demonstrator vehicle and Flight Test Engine (FTE) order to develop realistic requirements for the Ground Test Engine (GTE). The latest conceptual FTE and X-43B configuration is briefly reviewed. The project plan is to reduce risk to the GTE and FTE concepts through several tests: thruster, fuel endothermic characterization, engine structure/heat exchanger, injection characterization rig, and full scale direct connect combustion rig. Each of these will be discussed along with the project schedule. This discussion is limited due to ITAR restrictions on open literature papers.

System status display information

NASA Technical Reports Server (NTRS)

Summers, L. G.; Erickson, J. B.

1984-01-01

The system Status Display is an electronic display system which provides the flight crew with enhanced capabilities for monitoring and managing aircraft systems. Guidelines for the design of the electronic system displays were established. The technical approach involved the application of a system engineering approach to the design of candidate displays and the evaluation of a Hernative concepts by part-task simulation. The system engineering and selection of candidate displays are covered.

NASA GRC MBSE Implementation Status

NASA Technical Reports Server (NTRS)

Parrott, Edith; Trase, Katie; Green, Randi; Varga, Denise; Powell, Joe

2016-01-01

This presentation gives a brief overview on GRCs Model Based System Engineering (MBSE) implementation status. This overview covers: history, project usage and implementation, challenges and future work.

Automobile Engine Control Parameters Study : Volume 2. Status of Foreign Engine Control Practices.

DOT National Transportation Integrated Search

1977-02-01

The report contains the results of a study to evaluate automobile engine control parameters and their effects on vehicle fuel economy and emissions. Volume II treats selected foreign manufacturers. The principal topics reviewed for the twenty-eight e...

Think Engineer, Think Male?

ERIC Educational Resources Information Center

Male, Sally A.; Bush, Mark B.; Murray, Kevin

2009-01-01

Engineering education needs to develop the competencies required for engineering work, and attract and retain students from diverse backgrounds. This study investigated the possibility that the perceived importance of competencies is subconsciously influenced by gendered assumptions, and as a consequence, this lowers the status given to…

76 FR 63278 - Bayer CropScience LP; Determination of Nonregulated Status for Cotton Genetically Engineered for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-12

... for Cotton Genetically Engineered for Insect Resistance and Herbicide Tolerance AGENCY: Animal and... determination that a genetically engineered cotton developed by Bayer CropScience LP, designated as TwinLink TM cotton (events T304-40 and GHB119), which has been genetically engineered to be tolerant to the herbicide...

14 CFR 135.439 - Maintenance recording requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., propeller, and rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller... alterations and repairs to each airframe, engine, propeller, rotor, and appliance. (b) Each certificate holder... the records of the last complete overhaul of each airframe, engine, propeller, rotor, and appliance...

14 CFR 135.439 - Maintenance recording requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., propeller, and rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller... alterations and repairs to each airframe, engine, propeller, rotor, and appliance. (b) Each certificate holder... the records of the last complete overhaul of each airframe, engine, propeller, rotor, and appliance...

14 CFR 135.439 - Maintenance recording requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., propeller, and rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller... alterations and repairs to each airframe, engine, propeller, rotor, and appliance. (b) Each certificate holder... the records of the last complete overhaul of each airframe, engine, propeller, rotor, and appliance...

14 CFR 135.439 - Maintenance recording requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., propeller, and rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller... alterations and repairs to each airframe, engine, propeller, rotor, and appliance. (b) Each certificate holder... the records of the last complete overhaul of each airframe, engine, propeller, rotor, and appliance...

14 CFR 135.439 - Maintenance recording requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., propeller, and rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller... alterations and repairs to each airframe, engine, propeller, rotor, and appliance. (b) Each certificate holder... the records of the last complete overhaul of each airframe, engine, propeller, rotor, and appliance...

75 FR 6256 - Petition for Waiver of Compliance

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-08

... whereby the engineer and RCO qualification endorsement is placed into the employee's crew management... notifies the Crew Management Center and has the employee's engineer or RCO status changed from active to... CFR part 240, Qualification and Certification of Locomotive Engineers, specifically Section 129. CSXT...

24 CFR 585.401 - Recordkeeping by recipients.

Code of Federal Regulations, 2010 CFR

2010-04-01

... information as age, high school drop out status, income level, gender, employment status, and racial and..., architectural and engineering fees, construction, rehabilitation, operating costs or replacement reserves for...

The arrangement of deformation monitoring project and analysis of monitoring data of a hydropower engineering safety monitoring system

NASA Astrophysics Data System (ADS)

Wang, Wanshun; Chen, Zhuo; Li, Xiuwen

2018-03-01

The safety monitoring is very important in the operation and management of water resources and hydropower projects. It is the important means to understand the dam running status, to ensure the dam safety, to safeguard people’s life and property security, and to make full use of engineering benefits. This paper introduces the arrangement of engineering safety monitoring system based on the example of a water resource control project. The monitoring results of each monitoring project are analyzed intensively to show the operating status of the monitoring system and to provide useful reference for similar projects.

Educating Tomorrow's Engineers Act

THOMAS, 113th Congress

Rep. Tonko, Paul [D-NY-20

2013-06-18

House - 07/08/2013 Referred to the Subcommittee on Early Childhood, Elementary, and Secondary Education. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

A report from the 73rd Annual Meeting of the American Academy of Dermatology (March 20-24 - San Francisco, California, USA).

PubMed

Rabasseda, X

2015-04-01

With five late-breaking research in dermatology forums, a very intensive program of other forum sessions and a popular electronic poster session with a wealth of new clinical and preclinical research, many of which reflecting advances in the management of skin and skin structure diseases that either endanger the lives of patients or severely limit their quality of life and psychological wellbeing, the American Academy of Dermatology meeting gathered attendees from all around the world to its annual meeting in San Francisco. The following report highlights some of the most relevant new findings directly related with therapy for conditions such as psoriasis, nonmelanoma skin cancer, and other inflammatory, immunological and infectious diseases of the skin. Copyright 2015 Prous Science, S.A.U. or its licensors. All rights reserved.

Duchenne muscular dystrophy drugs face tough path to approval.

PubMed

Hodgkinson, L; Sorbera, L; Graul, A I

2016-03-01

Highly anticipated as new disease-modifying treatments for Duchenne muscular dystrophy (DMD), therapeutics by BioMarin Pharmaceutical (Kyndrisa™; drisapersen) and Sarepta Therapeutics (eteplirsen; AVI-4658) both recently received negative FDA reviews and are now facing battles for approval in the U.S. At present, BioMarin is committed to working with the FDA to forge a pathway to approval following the failure of its NDA, while Sarepta awaits the formal decision on its NDA, which is expected by late May 2016. Despite the critical nature of both reviews, analysts consider that there is still a narrow possibility of approval of both drugs. According to Consensus forecasts from Thomson Reuters Cortellis for Competitive Intelligence, Kyndrisa is forecast to achieve sales of USD 533.71 million in 2021. Copyright 2016 Prous Science, S.A.U. or its licensors. All rights reserved.

Memantine and donepezil: a fixed drug combination for the treatment of moderate to severe Alzheimer's dementia.

PubMed

Owen, R T

2016-04-01

Donepezil (and other cholinesterase inhibitors [ChEIs]) and memantine are the mainstays of treatment in Alzheimer's dementia, addressing respectively, the cholinergic and glutamatergic dysregulation which underlies or results from its pathophysiology. To alleviate the pill burden and swallowing difficulties associated with the condition, a fixed drug combination of extended-release memantine and donepezil was developed. This combination was shown to be both bioequivalent to the components administered separately and could be administered sprinkled over soft food. The mode of action, pharmacokinetics, clinical efficacy and safety and tolerability of the combination are discussed together with the wider, often conflicting trial literature of combination versus monotherapy with memantine and ChEIs, their meta-analyses and treatment guidelines. Copyright 2016 Prous Science, S.A.U. or its licensors. All rights reserved.

Research on the Undergraduate Financial Engineering Education in China

ERIC Educational Resources Information Center

Ma, Haiyong; Zhang, Weiwei

2011-01-01

The rapid development of modern economy has put forward higher requirements for financial engineering education. This paper analyzes the status and problems in undergraduate financial engineering education in china, such as indistinct training objective, rigid curriculum structure, and superficial teaching methods, etc. and puts forward…

RS-25 Rocket Engine Test

NASA Image and Video Library

2017-08-09

The 8.5-minute test conducted at NASA’s Stennis Space Center is part of a series of tests designed to put the upgraded former space shuttle engines through the rigorous temperature and pressure conditions they will experience during a launch. The tests also support the development of a new controller, or “brain,” for the engine, which monitors engine status and communicates between the rocket and the engine, relaying commands to the engine and transmitting data back to the rocket.

Engineering Education for Innovation Act

THOMAS, 112th Congress

Rep. Tonko, Paul [D-NY-21

2011-05-23

House - 09/08/2011 Referred to the Subcommittee on Early Childhood, Elementary, and Secondary Education. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Genetically Engineered Safety Act

THOMAS, 112th Congress

Rep. Kucinich, Dennis J. [D-OH-10

2011-12-02

House - 12/19/2011 Referred to the Subcommittee on Rural Development, Research, Biotechnology, and Foreign Agriculture. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Automotive technology status and projections. Volume 2: Assessment report

NASA Technical Reports Server (NTRS)

Dowdy, M.; Burke, A.; Schneider, H.; Edmiston, W.; Klose, G. J.; Heft, R.

1978-01-01

Current and advanced conventional engines, advanced alternative engines, advanced power train components, and other energy conserving automobile modifications which could be implemented by the end of this century are examined. Topics covered include gas turbine engines, Stirling engines, advanced automatic transmissions, alternative fuels, and metal and ceramic technology. Critical problems are examined and areas for future research are indicated.

Status of Real-Time Laser Based Ion Engine Diagnostics at NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Domonkos, Matthew T.; Williams, George J., Jr.

2001-01-01

The development status of laser based erosion diagnostics for ion engines at the NASA Glenn Research Center is discussed. The diagnostics are being developed to enhance component life-prediction capabilities. A direct measurement of the erosion product density using laser induced fluorescence (LIF) is described. Erosion diagnostics based upon evaluation of the ion dynamics are also under development, and the basic approach is presented. The planned implementation of the diagnostics is discussed.

The current status of rehabilitation engineering

NASA Technical Reports Server (NTRS)

Reswick, J. B.

1974-01-01

Mechanical and electrical engineering devices for paralytic patient care are discussed as they are applied to medical problems. These include means of preventing bedsores, mobility aids, upper extremity orthoses, and electrical stimulation.

Educating Tomorrow's Engineers Act

THOMAS, 113th Congress

Sen. Gillibrand, Kirsten E. [D-NY

2013-06-18

Senate - 06/18/2013 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Genetically Engineered Safety Act

THOMAS, 111th Congress

Rep. Kucinich, Dennis J. [D-OH-10

2010-06-23

House - 11/16/2010 Referred to the Subcommittee on Rural Development, Biotechnology, Specialty Crops, and Foreign Agriculture. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Status of Social Engineering Awareness in Business Organizations and Colleges/Universities

ERIC Educational Resources Information Center

Hauser, Deanna Mae

2017-01-01

Social engineers manipulate individuals into divulging confidential information or compromising personal or organizational security. The purpose of this qualitative case study was to examine the potential lack of social engineering awareness that affects employees at companies in southeastern Michigan. The research method consisted of interviews…

40 CFR 85.1706 - Pre-certification exemption.

Code of Federal Regulations, 2010 CFR

2010-07-01

... identification or engine serial number, indicate the use of the vehicle or engine on exempt status and indicate... identification and model year of vehicle or engine; or person or office to be contacted for further information... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Exclusion and Exemption of Motor Vehicles and Motor...

40 CFR 85.1706 - Pre-certification exemption.

Code of Federal Regulations, 2013 CFR

2013-07-01

... identification or engine serial number, indicate the use of the vehicle or engine on exempt status and indicate... identification and model year of vehicle or engine; or person or office to be contacted for further information... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Exclusion and Exemption of Motor Vehicles and Motor...

40 CFR 85.1706 - Pre-certification exemption.

Code of Federal Regulations, 2014 CFR

2014-07-01

... identification or engine serial number, indicate the use of the vehicle or engine on exempt status and indicate... identification and model year of vehicle or engine; or person or office to be contacted for further information... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Exclusion and Exemption of Motor Vehicles and Motor...

40 CFR 85.1706 - Pre-certification exemption.

Code of Federal Regulations, 2012 CFR

2012-07-01

... identification or engine serial number, indicate the use of the vehicle or engine on exempt status and indicate... identification and model year of vehicle or engine; or person or office to be contacted for further information... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Exclusion and Exemption of Motor Vehicles and Motor...

40 CFR 85.1706 - Pre-certification exemption.

Code of Federal Regulations, 2011 CFR

2011-07-01

... identification or engine serial number, indicate the use of the vehicle or engine on exempt status and indicate... identification and model year of vehicle or engine; or person or office to be contacted for further information... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Exclusion and Exemption of Motor Vehicles and Motor...

Growth of Engineering Education in India: Status, Issues, and Challenges

ERIC Educational Resources Information Center

Choudhury, Pradeep Kumar

2016-01-01

This article examines the growth of engineering education in India in the post-economic reform period using the secondary data published by Ministry of Human Resource Development, University Grants Commission and All India Council for Technical Education. Particularly, this article has focused on three important dimensions of engineering and…

77 FR 41356 - Monsanto Co.; Availability of Petition for Determination of Nonregulated Status of Soybean...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... Engineered for Herbicide Tolerance AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Notice... soybean designated as MON 87708, which has been genetically engineered for tolerance to the herbicide... MON 87708, which has been genetically engineered for tolerance to the herbicide dicamba, stating that...

78 FR 66892 - BASF Plant Science LP; Availability of Plant Pest Risk Assessment and Environmental Assessment...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

... Determination of Nonregulated Status of Soybean Genetically Engineered for Herbicide Resistance AGENCY: Animal... genetically engineered for resistance to herbicides in the imidazolinone family. We are soliciting comments on... genetically engineered for resistance to herbicides in the imidazolinone family. The petition states that this...

77 FR 41353 - GENECTIVE SA; Availability of Petition for Determination of Nonregulated Status of Maize...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... Engineered for Herbicide Tolerance AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Notice... VCO-[Oslash]1981-5, which has been genetically engineered for tolerance to the herbicide glyphosate...- [Oslash]1981-5, which has been genetically engineered for tolerance to the herbicide glyphosate, stating...

76 FR 7191 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-09

... Internal Combustion Engines (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice... Combustion Engines (Renewal) ICR Numbers: EPA ICR Number 2227.03, OMB Control Number 2060-0610. ICR Status... internal combustion engines. Estimated Number of Respondents: 17,052. Frequency of Response: Initially and...

14 CFR 91.1439 - CAMP: Maintenance recording requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... service of the airframe, engine, propeller, and rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller, rotor, and appliance. (iii) The time since last overhaul of each item... required. (vi) A list of current major alterations and repairs to each airframe, engine, propeller, rotor...

14 CFR 91.1439 - CAMP: Maintenance recording requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... service of the airframe, engine, propeller, and rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller, rotor, and appliance. (iii) The time since last overhaul of each item... required. (vi) A list of current major alterations and repairs to each airframe, engine, propeller, rotor...

14 CFR 121.380 - Maintenance recording requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... section, the total time in service of each engine and propeller. (iii) The current status of life-limited parts of each airframe, engine, propeller, and appliance. (iv) The time since last overhaul of all items... required. (vii) A list of current major alterations to each airframe, engine, propeller, and appliance. (b...

14 CFR 121.380 - Maintenance recording requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... section, the total time in service of each engine and propeller. (iii) The current status of life-limited parts of each airframe, engine, propeller, and appliance. (iv) The time since last overhaul of all items... required. (vii) A list of current major alterations to each airframe, engine, propeller, and appliance. (b...

14 CFR 121.380 - Maintenance recording requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... section, the total time in service of each engine and propeller. (iii) The current status of life-limited parts of each airframe, engine, propeller, and appliance. (iv) The time since last overhaul of all items... required. (vii) A list of current major alterations to each airframe, engine, propeller, and appliance. (b...

14 CFR 91.1439 - CAMP: Maintenance recording requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... service of the airframe, engine, propeller, and rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller, rotor, and appliance. (iii) The time since last overhaul of each item... required. (vi) A list of current major alterations and repairs to each airframe, engine, propeller, rotor...

14 CFR 121.380 - Maintenance recording requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... section, the total time in service of each engine and propeller. (iii) The current status of life-limited parts of each airframe, engine, propeller, and appliance. (iv) The time since last overhaul of all items... required. (vii) A list of current major alterations to each airframe, engine, propeller, and appliance. (b...

14 CFR 91.1439 - CAMP: Maintenance recording requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... service of the airframe, engine, propeller, and rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller, rotor, and appliance. (iii) The time since last overhaul of each item... required. (vi) A list of current major alterations and repairs to each airframe, engine, propeller, rotor...

14 CFR 121.380 - Maintenance recording requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... section, the total time in service of each engine and propeller. (iii) The current status of life-limited parts of each airframe, engine, propeller, and appliance. (iv) The time since last overhaul of all items... required. (vii) A list of current major alterations to each airframe, engine, propeller, and appliance. (b...

14 CFR 91.1439 - CAMP: Maintenance recording requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... service of the airframe, engine, propeller, and rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller, rotor, and appliance. (iii) The time since last overhaul of each item... required. (vi) A list of current major alterations and repairs to each airframe, engine, propeller, rotor...

Current Status of an Organic Rankine Cycle Engine Development Program

NASA Technical Reports Server (NTRS)

Barber, R. E.

1984-01-01

The steps taken to achieve improved bearing life in the organic Rankine cycle (ORC) engine being developed for use on solar parabolic dishes are presented. A summary of test results is given. Dynamic tests on the machine shaft and rotors of the ORC engine are also discussed.

Status of Elementary Teacher Development: Preparing Elementary Teachers to Deliver Technology and Engineering Experiences

ERIC Educational Resources Information Center

Rose, Mary Annette; Carter, Vinson; Brown, Josh; Shumway, Steven

2017-01-01

For over a century, teacher preparation programs (TPPs) have experienced peaks and valleys in preparing preservice teachers to deliver technology and engineering (TE) experiences in elementary classrooms. Calls to integrate engineering concepts into elementary education (Katehi, Pearson, & Feder, 2009; Kimmel, Carpinelli, Curr-Alexander, &…

Evaluating Instructional Design Models: A Proposed Research Approach

ERIC Educational Resources Information Center

Gropper, George L.

2015-01-01

Proliferation of prescriptive models in an "engineering" field is not a sign of its maturity. Quite the opposite. Materials engineering, for example, meets the criterion of parsimony. Sadly, the very large number of models in "instructional design," putatively an engineering field, raises questions about its status. Can the…

76 FR 37771 - Monsanto Co.; Availability of Petition, Plant Pest Risk Assessment, and Environmental Assessment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-28

... Determination of Nonregulated Status for Soybean Genetically Engineered To Have a Modified Fatty Acid Profile... soybean designated as MON 87705, which has been genetically engineered to have a modified fatty acid... our regulations concerning the introduction of certain genetically engineered organisms and products...

75 FR 20560 - Syngenta Biotechnology, Inc.; Determination of Nonregulated Status for Corn Genetically...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-20

...] Syngenta Biotechnology, Inc.; Determination of Nonregulated Status for Corn Genetically Engineered for... are advising the public of our determination that a corn line developed by Syngenta Biotechnology, Inc... Biotechnology, Inc., in its petition for a determination of nonregulated status, our analysis of other...

Engineering Education for Innovation Act

THOMAS, 111th Congress

Sen. Gillibrand, Kirsten E. [D-NY

2010-02-25

Senate - 02/25/2010 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Evolution of the Systems Engineering Education Development (SEED) Program at NASA Goddard Space Flight Center

NASA Technical Reports Server (NTRS)

Bagg, Thomas C., III; Brumfield, Mark D.; Jamison, Donald E.; Granata, Raymond L.; Casey, Carolyn A.; Heller, Stuart

2003-01-01

The Systems Engineering Education Development (SEED) Program at NASA Goddard Space Flight Center develops systems engineers from existing discipline engineers. The program has evolved significantly since the report to INCOSE in 2003. This paper describes the SEED Program as it is now, outlines the changes over the last year, discusses current status and results, and shows the value of human systems and leadership skills for practicing systems engineers.

Development of Supersonic Vehicle for Demonstration of a Precooled Turbojet Engine

NASA Astrophysics Data System (ADS)

Sawai, Shujiro; Fujita, Kazuhisa; Kobayashi, Hiroaki; Sakai, Shin'ichiro; Bando, Nobutaka; Kadooka, Shouhei; Tsuboi, Nobuyuki; Miyaji, Koji; Uchiyama, Taku; Hashimoto, Tatsuaki

JAXA is developing Mach 5 hypersonic turbojet engine technology that can be applied in a future hypersonic transport. Now, Jet Engine Technology Research Center of JAXA conducts the experimental study using a 1 / 10 scale-model engine. In parallel to engine development activities, a new supersonic flight-testing vehicle for the hypersonic turbojet engine is under development since 2004. In this paper, the system configuration of the flight-testing vehicle is outlined and development status is reported.

[Current status of bone/cartilage tissue engineering towards clinical applications].

PubMed

Ohgushi, Hajime

2014-10-01

Osteo/chondrogenic differentiation capabilities are seen after in vivo implantation of mesenchymal stem cells (MSCs), which are currently used for the patients having bone/cartilage defects. Importantly, the differentiation capabilities are induced by culturing technology, resulting in in vitro bone/cartilage formation. Especially, the in vitro bone tissue is useful for bone tissue regeneration. For cartilage regeneration, culture expanded chondrocytes derived from patient's normal cartilage are also used for the patients having cartilage damages. Recently, the cultured chondrocytes embedded in atelocollagen gel are obtainable as tissue engineered products distributed by Japan Tissue Engineering Co. Ltd. The products are available in the well-regulated hospitals by qualified orthopedic surgeons. The criteria for these hospitals/surgeons have been established. This review paper focuses on current status of bone/cartilage tissue engineering towards clinical applications in Japan.

Corps of Engineers Cooperative Joint Management Restoration Act

THOMAS, 113th Congress

Sen. Boozman, John [R-AR

2014-02-27

Senate - 12/12/2014 Placed on Senate Legislative Calendar under General Orders. Calendar No. 652. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Genetically Engineered Food Right-to-Know Act

THOMAS, 113th Congress

Sen. Boxer, Barbara [D-CA

2013-04-24

Senate - 04/24/2013 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

A bill to require the Consumer Product Safety Commission to study and report on the impact on consumers of permitting an increase in the amount of ethanol blended with gasoline for use in gasoline-powered engines used in vehicles operated in interstate commerce, on public streets and roads, or offroad, appliances such as lawn mowers and other nonvehicular devices, and marine engines, and to require the National Highway Traffic Safety Administration to study and report on any safety or reliability impact of such an increase on motor vehicle engines and fuel systems.

THOMAS, 111th Congress

Sen. Hutchison, Kay Bailey [R-TX

2010-09-29

Senate - 09/29/2010 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Advanced OTV engine concepts

NASA Technical Reports Server (NTRS)

Zachary, A. T.

1984-01-01

The results and status of engine technology efforts to date and related company funded activities are presented. Advanced concepts in combustors and injectors, high speed turbomachinery, controls, and high-area-ratio nozzles that package within a short length result is engines with specific impulse values 35 to 46 seconds higher than those now realized by operational systems. The improvement in life, reliability, and maintainability of OTV engines are important.

Probing Enzyme-Surface Interactions via Protein Engineering and Single-Molecule Techniques

DTIC Science & Technology

2017-06-26

SECURITY CLASSIFICATION OF: The overall objective of this research was to exploit protein engineering and fluorescence single-molecule methods to... Engineering and Single-Molecule Techniques The views, opinions and/or findings contained in this report are those of the author(s) and should not...Status: Technology Transfer: Report Date: 1 FINAL REPORT Project Title: Probing Enzyme-Surface Interactions via Protein Engineering and

Evaluation of heat engine for hybrid vehicle application

NASA Technical Reports Server (NTRS)

Schneider, H. W.

1984-01-01

The status of ongoing heat-engine developments, including spark-ignition, compression-ignition, internal-combustion, and external-combustion engines is presented. The potential of engine concepts under consideration for hybrid vehicle use is evaluated, using self-imposed criteria for selection. The deficiencies of the engines currently being evaluated in hybrid vehicles are discussed. Focus is on recent research with two-stroke, rotary, and free-piston engines. It is concluded that these engine concepts have the most promising potential for future application in hybrid vehicles. Recommendations are made for analysis and experimentation to evaluate stop-start and transient emission behavior of recommended engine concepts.

Space Civil Engineering option - A progress report

NASA Technical Reports Server (NTRS)

Criswell, Marvin E.; Sadeh, Willy Z.

1992-01-01

Space Civil Engineering is an emerging engineering discipline that focuses on extending and expanding Civil Engineering to the development, operation, and maintenance of infrastructures on celestial bodies. Space Civil Engineering is presently being developed as a new discipline within the Department of Civil Engineering at Colorado State University and with support of the NASA Space Grant College Program. Academic programs geared toward creating Space Civil Engineering Options at both undergraduate and graduate levels are being formulated. Basic ideas and concepts and the current status of the curriculum in the Space Civil Engineering Option primarily at the undergraduate level are presented.

Masculinities in Organizational Cultures in Engineering Education in Europe: Results of the European Union Project WomEng

ERIC Educational Resources Information Center

Sagebiel, F.; Dahmen, J.

2006-01-01

The paper describes elements of engineering organizational cultures and structures in higher engineering education from the European project WomEng. Hypotheses, based on state of the art, refer to: women friendly presentation, attractiveness of interdisciplinary teaching methods, single sex education, perceptions of minority status, feelings of…

78 FR 13305 - Syngenta Seeds, Inc., and Bayer CropScience AG; Availability of Petition for Determination of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-27

... Status of Soybean Genetically Engineered for Herbicide Tolerance AGENCY: Animal and Plant Health... SYHTOH2, which has been genetically engineered for tolerance to the herbicides glufosinate and mesotrione... engineered to tolerate exposure to the herbicides glufosinate and mesotrione. Glufosinate tolerance is not a...

77 FR 52323 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-29

...- Ignition Engines (Renewal). ICR Numbers: EPA ICR No. 1695.10, OMB Control No. 2060-0338. ICR Status: This... Engines and Equipment, OMB Control Number 2060-0603) were incorporated into ICR 1695.10. This action was... Requirements for Nonroad Spark-Ignition Engines (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION...

Teacher Challenges to Implement Engineering Design in Secondary Technology Education

ERIC Educational Resources Information Center

Kelley, Todd R.; Wicklein, Robert C.

2009-01-01

This descriptive study examined the current status of technology education teacher practices with respect to engineering design. This article is the third article in a three-part series presenting the results of this study. The first article in the series titled "Examination of Engineering Design Curriculum Content" highlighted the research…

RS 25 Hot Fire test

NASA Image and Video Library

2016-08-18

The 7.5-minute test conducted at NASA’s Stennis Space Center is part of a series of tests designed to put the upgraded former space shuttle engines through the rigorous temperature and pressure conditions they will experience during a launch. The tests also support the development of a new controller, or “brain,” for the engine, which monitors engine status and communicates between the rocket and the engine, relaying commands to the engine and transmitting data back to the rocket.

RS-25 Hot Fire test

NASA Image and Video Library

2016-08-18

The 7.5-minute test conducted at NASA’s Stennis Space Center is part of a series of tests designed to put the upgraded former space shuttle engines through the rigorous temperature and pressure conditions they will experience during a launch. The tests also support the development of a new controller, or “brain,” for the engine, which monitors engine status and communicates between the rocket and the engine, relaying commands to the engine and transmitting data back to the rocket.

ADDRESSING ENVIRONMENTAL ENGINEERING CHALLENGES WITH COMPUTATIONAL FLUID DYNAMICS

EPA Science Inventory

This paper discusses the status and application of Computational Fluid Dynamics )CFD) models to address environmental engineering challenges for more detailed understanding of air pollutant source emissions, atmospheric dispersion and resulting human exposure. CFD simulations ...

Variable-cycle engines for supersonic cruise aircraft

NASA Technical Reports Server (NTRS)

Willis, E.

1976-01-01

Progress and the current status of the Variable Cycle Engine (VCE) study are reviewed with emphasis placed on the impact of technology advancements and design specifications. A large variety of VCE concepts are also examined.

ENGINEERING BULLETIN: SUPERCRITICAL WATER OXIDATION

EPA Science Inventory

This engineering bulletin presents a description and status of supercritical water oxidation technology, a summary of recent performance tests, and the current applicability of this emerging technology. This information is provided to assist remedial project managers, contractors...

Dynamic modeling and vibration characteristics analysis of the aero-engine dual-rotor system with Fan blade out

NASA Astrophysics Data System (ADS)

Yu, Pingchao; Zhang, Dayi; Ma, Yanhong; Hong, Jie

2018-06-01

Fan Blade Out (FBO) from a running rotor of the turbofan engine will not only introduce the sudden unbalance and inertia asymmetry into the rotor, but also apply large impact load and induce rotor-to-stator rubbing on the rotor, which makes the mass, gyroscopic and stiffness matrixes of the dynamic equation become time-varying and highly nonlinear, consequently leads to the system's complicated vibration. The dynamic analysis of the aero-engine rotor system is one essential requirement of the authorities and is vital to the aero-engine's safety. The paper aims at studying the dynamic responses of the complicated dual-rotor systems at instantaneous and windmilling statuses when FBO event occurs. The physical process and mechanical characteristics of the FBO event are described qualitatively, based on which the dynamic modeling for an aero-engine dual-rotor system is carried out considering several excitations caused by FBO. Meanwhile the transient response during the instantaneous status and steady-state response at the windmilling status are obtained. The results reveal that the sudden unbalance can induce impact load to the rotor, and lead to the sharp increase of the vibration amplitude and reaction force. The rub-impact will apply constraint effects on the rotor and restrict the transient vibration amplitude, while the inertia asymmetry has little influence on the transient response. When the rotor with huge unbalance operates at windmilling status, the rub-impact turns to be the main factor determining the rotor's dynamic behavior, and several potential motion states, such as instable dry whip, intermittent rubbing and synchronous full annular rubbing would happen on certain conditions.

Elevating Science, Technology, Engineering, and Mathematics Education Act of 2010

THOMAS, 111th Congress

Rep. Honda, Michael M. [D-CA-15

2010-09-29

House - 11/18/2010 Referred to the Subcommittee on Higher Education, Lifelong Learning, and Competitiveness. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Enhancing Science, Technology, Engineering, and Mathematics Education Act of 2009

THOMAS, 111th Congress

Rep. Honda, Michael M. [D-CA-15

2009-06-04

House - 07/23/2009 Referred to the Subcommittee on Early Childhood, Elementary, and Secondary Education. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

An American knowledge base in England - Alternate implementations of an expert system flight status monitor

NASA Technical Reports Server (NTRS)

Butler, G. F.; Graves, A. T.; Disbrow, J. D.; Duke, E. L.

1989-01-01

A joint activity between the Dryden Flight Research Facility of the NASA Ames Research Center (Ames-Dryden) and the Royal Aerospace Establishment (RAE) on knowledge-based systems has been agreed. Under the agreement, a flight status monitor knowledge base developed at Ames-Dryden has been implemented using the real-time AI (artificial intelligence) toolkit MUSE, which was developed in the UK. Here, the background to the cooperation is described and the details of the flight status monitor and a prototype MUSE implementation are presented. It is noted that the capabilities of the expert-system flight status monitor to monitor data downlinked from the flight test aircraft and to generate information on the state and health of the system for the test engineers provides increased safety during flight testing of new systems. Furthermore, the expert-system flight status monitor provides the systems engineers with ready access to the large amount of information required to describe a complex aircraft system.

Overcoming Present-Day Powerplant Limitations Via Unconventional Engine Configurations

NASA Technical Reports Server (NTRS)

Meitner, Peter L.

2006-01-01

The Army Research Laboratory s Vehicle Technology Directorate is sponsoring the prototype development of three unconventional engine concepts - two intermittent combustion (IC) engines and one turbine engine (via SBIR (Small Business Innovative Research) contracts). The IC concepts are the Nutating Engine and the Bonner Engine, and the turbine concept is the POWER Engine. Each of the three engines offers unique and greatly improved capabilities (which cannot be achieved by present-day powerplants), while offering significant reductions in size and weight. This paper presents brief descriptions of the physical characteristics of the three engines, and discusses their performance potentials, as well as their development status.

Biomedical engineering education--status and perspectives.

PubMed

Magjarevic, Ratko; Zequera Diaz, Martha L

2014-01-01

Biomedical Engineering programs are present at a large number of universities all over the world with an increasing trend. New generations of biomedical engineers have to face the challenges of health care systems round the world which need a large number of professionals not only to support the present technology in the health care system but to develop new devices and services. Health care stakeholders would like to have innovative solutions directed towards solving problems of the world growing incidence of chronic disease and ageing population. These new solutions have to meet the requirements for continuous monitoring, support or care outside clinical settlements. Presence of these needs can be tracked through data from the Labor Organization in the U.S. showing that biomedical engineering jobs have the largest growth at the engineering labor market with expected 72% growth rate in the period from 2008-2018. In European Union the number of patents (i.e. innovation) is the highest in the category of biomedical technology. Biomedical engineering curricula have to adopt to the new needs and for expectations of the future. In this paper we want to give an overview of engineering professions in related to engineering in medicine and biology and the current status of BME education in some regions, as a base for further discussions.

MI1AENG1

Atmospheric Science Data Center

2014-09-03

MI1AENG1 MISR Level 1A Engineering Data File Type 1: Reformatted Annotated Level 1A product for the camera engineering data, which represents indicators of sampled measurements. ... Status Production Report Read Software Files :  Data Product Specification Versioning ...

Overview of free-piston Stirling SP-100 activities at the NASA Lewis Research Center

NASA Technical Reports Server (NTRS)

Slaby, J. G.

1986-01-01

An overview of the National Aeronautics and Space Administration (NASA) Lewis Research Center (LeRC) SP-100 free-piston Stirling engine activities is presented. These activities are being conducted in support of the Department of Defense (DOD), Department of Energy (DOE), and NASA. The space-power technology effort, under SP-100, addresses the status of the 25 kWe Space Power Demonstrator Engine (SPDE). Another facet of the SP-100 project covers the status of an endurance test. Dynamic balancing of the SPDE engine is discussed along with a summary covering the parametric results of a study showing the relationship between power-converter specific weight and efficiency both as a function of Stirling engine heater to cooler temperature ratio. Design parameters and conceptual design features are presented for a 25 kWe, single-cylinder free-piston Stirling space-power converter. And finally, a description of a hydrodynamic gas bearing concept is presented.

Design approaches to more energy efficient engines

NASA Technical Reports Server (NTRS)

Saunders, N. T.; Colladay, R. S.; Macioce, L. E.

1978-01-01

The status of NASA's Energy Efficient Engine Project, a comparative government-industry effort aimed at advancing the technology base for the next generation of large turbofan engines for civil aircraft transports is summarized. Results of recently completed studies are reviewed. These studies involved selection of engine cycles and configurations that offer potential for at least 12% lower fuel consumption than current engines and also are economically attractive and environmentally acceptable. Emphasis is on the advancements required in component technologies and systems design concepts to permit future development of these more energy efficient engines.

Stratified charge rotary engine for general aviation

NASA Technical Reports Server (NTRS)

Mount, R. E.; Parente, A. M.; Hady, W. F.

1986-01-01

A development history, a current development status assessment, and a design feature and performance capabilities account are given for stratified-charge rotary engines applicable to aircraft propulsion. Such engines are capable of operating on Jet-A fuel with substantial cost savings, improved altitude capability, and lower fuel consumption by comparison with gas turbine powerplants. Attention is given to the current development program of a 400-hp engine scheduled for initial operations in early 1990. Stratified charge rotary engines are also applicable to ground power units, airborne APUs, shipboard generators, and vehicular engines.

Embedded expert system for space shuttle main engine maintenance

NASA Technical Reports Server (NTRS)

Pooley, J.; Thompson, W.; Homsley, T.; Teoh, W.; Jones, J.; Lewallen, P.

1987-01-01

The SPARTA Embedded Expert System (SEES) is an intelligent health monitoring system that directs analysis by placing confidence factors on possible engine status and then recommends a course of action to an engineer or engine controller. The technique can prevent catastropic failures or costly rocket engine down time because of false alarms. Further, the SEES has potential as an on-board flight monitor for reusable rocket engine systems. The SEES methodology synergistically integrates vibration analysis, pattern recognition and communications theory techniques with an artificial intelligence technique - the Embedded Expert System (EES).

New thrombopoietin receptor agonists for platelet disorders.

PubMed

Homeida, S; Ebdon, C; Batty, P; Jackson, B; Kolade, S; Bateman, C; Peng, Y Y; Stasi, R

2012-04-01

Since thrombopoietin (TPO) was cloned in 1994, TPO receptor (TPO-R) agonists have been developed which have shown significant clinical activity in various conditions characterized by thrombocytopenia. First-generation TPO-R agonists were recombinant forms of human TPO. The clinical development of these molecules was discontinued after one of them, pegylated recombinant human megakaryocyte growth and development factor, was associated with the development of neutralizing autoantibodies cross-reacting with endogenous TPO. Second-generation TPO-R agonists are now available, which present no sequence homology to endogenous TPO. Two of these new agents, romiplostim and eltrombopag, have been granted marketing authorization for use in patients with primary immune thrombocytopenia unresponsive to conventional treatments. Clinical trials with TPO-R agonists are also ongoing in other thrombocytopenias, such as hepatitis C virus-related thrombocytopenia and the myelodysplastic syndromes. Copyright 2012 Prous Science, S.A.U. or its licensors. All rights reserved.

Venetoclax: Bcl-2 inhibition for the treatment of chronic lymphocytic leukemia.

PubMed

Del Poeta, G; Postorino, M; Pupo, L; Del Principe, M I; Dal Bo, M; Bittolo, T; Buccisano, F; Mariotti, B; Iannella, E; Maurillo, L; Venditti, A; Gattei, V; de Fabritiis, P; Cantonetti, M; Amadori, S

2016-04-01

Venetoclax (ABT-199) is a small-molecule selective oral inhibitor of the antiapoptotic protein Bcl-2 that promotes programmed cell death of chronic lymphocytic leukemia (CLL) cells regulating the release of proapoptotic factors, such as Smac/Diablo, apoptosis-inducing factor (AIF) and cytochrome c. In April 2016, the U.S. Food and Drug Administration (FDA) granted accelerated approval to venetoclax for patients diagnosed with CLL with 17p deletion, as detected by an FDA-approved test, who have received at least one prior therapy. This review will focus on the mechanism of action, preclinical studies and clinical development of venetoclax both as a monotherapy and in combination with other drugs for CLL in the current milieu of therapy dominated by novel tyrosine kinase inhibitors such as ibrutinib and idelalisib. Copyright 2016 Prous Science, S.A.U. or its licensors. All rights reserved.

Decision support tool for used oil regeneration technologies assessment and selection.

PubMed

Khelifi, Olfa; Dalla Giovanna, Fabio; Vranes, Sanja; Lodolo, Andrea; Miertus, Stanislav

2006-09-01

Regeneration is the most efficient way of managing used oil. It saves money by preventing costly cleanups and liabilities that are associated with mismanagement of used oil, it helps to protect the environment and it produces a technically renewable resource by enabling an indefinite recycling potential. There are a variety of processes and licensors currently offering ways to deal with used oils. Selecting a regeneration technology for used oil involves "cross-matching" key criteria. Therefore, the first prototype of spent oil regeneration (SPORE), a decision support tool, has been developed to help decision-makers to assess the available technologies and select the preferred used oil regeneration options. The analysis is based on technical, economical and environmental criteria. These criteria are ranked to determine their relative importance for a particular used oil regeneration project. The multi-criteria decision analysis (MCDA) is the core of the SPORE using the PROMETHEE II algorithm.

Concentrating Solar Power Projects - Maricopa Solar Project | Concentrating

Science.gov Websites

Turbine Capacity: Net: 1.5 MW Gross: 1.5 MW Status: Currently Non-Operational Start Year: 2010 Do you have more information, corrections, or comments? Background Technology: Dish/Engine Status: Currently Non

Undergraduate Scholarship Awards in Science, Technology, Engineering, or Mathematics Act

THOMAS, 111th Congress

Sen. Gillibrand, Kirsten E. [D-NY

2010-09-23

Senate - 09/23/2010 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Auxiliary engine digital interface unit (DIU)

NASA Technical Reports Server (NTRS)

1972-01-01

This auxiliary propulsion engine digital unit controls both the valving of the fuel and oxidizer to the engine combustion chamber and the ignition spark required for timely and efficient engine burns. In addition to this basic function, the unit is designed to manage it's own redundancy such that it is still operational after two hard circuit failures. It communicates to the data bus system several selected information points relating to the operational status of the electronics as well as the engine fuel and burning processes.

77 FR 41350 - Monsanto Co.; Determination of Nonregulated Status of Soybean Genetically Engineered To Produce...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... MON 87769, which has been genetically engineered to produce stearidonic acid, an omega-3 fatty acid... 87769, which has been genetically engineered to produce stearidonic acid, an omega-3 fatty acid not... NEPA (40 CFR parts 1500-1508), (3) USDA regulations implementing NEPA (7 CFR part 1b), and (4) APHIS...

78 FR 13303 - Stine Seed Farm, Inc.; Availability of Plant Pest Risk Assessment, Environmental Assessment, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-27

... reason to believe are plant pests. Such genetically engineered organisms (GE) and products are considered... genetically engineered organisms. Paragraph (e) of Sec. 340.6 provides that APHIS will publish a notice in the... Preliminary Decision for an Extension of a Determination of Nonregulated Status of Corn Genetically Engineered...

Science and Engineering Personnel: A National Overview. Surveys of Science Resources Series.

ERIC Educational Resources Information Center

National Science Foundation, Washington, DC. Div. of Science Resources Studies.

This is the third in a biennial series of reports designed to furnish a comprehensive overview of the status of United States scientific and technological efforts as they relate to the employment and other characteristics of science and engineering (S/E) personnel. Chapter I discusses the utilization patterns of scientists and engineers, examining…

Overview of liquid lubricants for advanced aircraft

NASA Technical Reports Server (NTRS)

Loomis, W. R.

1982-01-01

An overall status report on liquid lubricants for use in high-performance turbojet engines is presented. Emphasis is placed on the oxidation and thermal stability requirements imposed upon the lubrication system. A brief history is iven of the development of turbine engine lubricants which led to synthetic oils with their inherent modification advantages. The status and state of development of some nine candidate classes of fluids for use in advanced turbine engines are discussed. Published examples of fundamental studies to obtain a better understanding of the chemistry involved in fluid degradation are reviewed. Also, alternatives to high temperature fluid development are described. The importance of of continuing work on improving high temperature lubricant candidates and encouraging development of fluid base stocks is discussed.

Design of an expert-system flight status monitor

NASA Technical Reports Server (NTRS)

Regenie, V. A.; Duke, E. L.

1985-01-01

The modern advanced avionics in new high-performance aircraft strains the capability of current technology to safely monitor these systems for flight test prior to their generalized use. New techniques are needed to improve the ability of systems engineers to understand and analyze complex systems in the limited time available during crucial periods of the flight test. The Dryden Flight Research Facility of NASA's Ames Research Center is involved in the design and implementation of an expert system to provide expertise and knowledge to aid the flight systems engineer. The need for new techniques in monitoring flight systems and the conceptual design of an expert-system flight status monitor is discussed. The status of the current project and its goals are described.

The influence of activities and nutrition status to university students' achievements

NASA Astrophysics Data System (ADS)

Fathonah, Siti

2018-03-01

The purpose of this research is to analyse the influence of activity and nutrition status to the achievement of students from Engineering Faculty of UNNES. The subject of this research is the students of Engineering Faculty of UNNES. Using proportional random sampling, there are 5% (214 students of 2015 batch) taken as the samples of the research. The methods of collecting the data were using documentation from akademik.unnes.ac.id on students' achievement, questionnaire to ask upon students' activity, and BMI measurement for nutrition status. The data analysis was using percentage description, chi-square analysis, and regression. The data obtained that the average grade points of engineering students are satisfying in the level of 3.29 with light activities with the energy of 2.220 kkal. The average sleeping time of the students were 5.68 hours, whereas the total of their studying and private activity were 18.18 hours. The status of students' nutrition is Normal weight with the details of 64.2% of students are Normal weight, 23.5% of them are wasting, 4.0% are overweight, and 5.2% are obesity. The activity and nutrition status were proven not significantly influencing students grade point of achievements. The suggestions proposed by the researcher are 1) the students need to increase their sleeping time to be 6-9 hours, and they need to habituate themselves in working out at least 3 times a week in 30 - 45 minutes, and 2) further research on nutrition status and students' achievements can focus on the influence of food consumption and students' clean lifestyle.

78 FR 25941 - Stine Seed Farm, Inc.; Extension of a Determination of Nonregulated Status of Corn Genetically...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-03

... Engineered for Herbicide Resistance AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Notice... maize line HCEM485, which has been genetically engineered to be resistant to the herbicide glyphosate...

Fracture mechanics /Dryden Lecture/. [aerospace structural design applications

NASA Technical Reports Server (NTRS)

Hardrath, H. F.

1974-01-01

A historical outline of the engineering discipline of fracture mechanics is presented, and current analytical procedures are summarized. The current status of the discipline is assessed, and engineering applications are discussed, along with recommended directions for future study.

Wind tunnel productivity status and improvement activities at NASA Langley Research Center

NASA Technical Reports Server (NTRS)

Putnam, Lawrence E.

1996-01-01

Over the last three years, a major effort has been underway to re-engineering the way wind tunnel testing is accomplished at the NASA Langley Research Center. This effort began with the reorganization of the LaRC and the consolidation of the management of the wind tunnels in the Aerodynamics Division under one operations branch. This paper provides an overview of the re-engineering activities and gives the status of the improvements in the wind tunnel productivity and customer satisfaction that have resulted from the new ways of working.

Removing Repeated Executive Delays to Transboundary Approvals of Pipelines and Engineering Act

THOMAS, 113th Congress

Sen. Walsh, John E. [D-MT

2014-05-08

Senate - 05/08/2014 Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Coatings for aircraft gas turbine engines and space shuttle heat shields: A review of Lewis Research Center programs

NASA Technical Reports Server (NTRS)

Grisaffe, S. J.; Merutka, J. P.

1972-01-01

The status of several coating programs is reviewed. These include efforts on protecting aircraft gas turbine engine materials from oxidation/corrosion and on protecting refractory metal reentry heat shields from oxidation.

A Modular Artificial Intelligence Inference Engine System (MAIS) for support of on orbit experiments

NASA Technical Reports Server (NTRS)

Hancock, Thomas M., III

1994-01-01

This paper describes a Modular Artificial Intelligence Inference Engine System (MAIS) support tool that would provide health and status monitoring, cognitive replanning, analysis and support of on-orbit Space Station, Spacelab experiments and systems.

Progreen Online Engineering Diploma in the Middle East: Assessment of the Educational Experience

ERIC Educational Resources Information Center

Baytiyeh, Hoda

2018-01-01

Little is known about the status of online learning in the Middle East. This study investigates educational experiences of engineers enrolled in the new joint online ProGreen diploma programme offered by three universities, two in Lebanon and one in Egypt. Forty-eight working engineers responded to an online survey based on the three components of…

A bill to promote the potential of women in academic science, technology, engineering, and mathematics.

THOMAS, 111th Congress

Sen. Udall, Tom [D-NM

2010-07-12

Senate - 07/12/2010 Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Development status of LE-7 fuel turbopump

NASA Astrophysics Data System (ADS)

Nakano, T.; Nagao, R.; Ohta, T.; Warashina, S.; Watanabe, H.; Oguchi, H.

The liquid hydrogen turbopump (LH2 T/P) for the LE-7 engine has been developed since 1984. The component PDR was held in June 1988 and the basic troubles occurred at the development test were solved. Next, the component CDR-1 was held in December 1989 in order to feed back the test results of prototype LH2 T/P model to the design of qualification phase T/P. So, the production of these turbopumps was admitted. Recently, the component CDR-2 was held in February 1992 to reflect the counterparts adopted for some troubles (impeller and turbine blade cracks and so on) in long-time engine tests to the design of qualification phase T/P. In the qualification phase, the hydraulic characteristics and strength in the engine operating range were examined at the LH2 T/P component test, and its endurance confirmed at the engine tests. The LH2 turbopump component test was held at NASDA Kakuda and the engine test at Tashiro and Tanegashima. This paper describes the development status of LH2 T/P, containing the design description and the content of some troubles and its counterplans.

Heat engine development for solar thermal power systems

NASA Astrophysics Data System (ADS)

Pham, H. Q.; Jaffe, L. D.

The parabolic dish solar collector systems for converting sunlight to electrical power through a heat engine will, require a small heat engine of high performance long lifetime to be competitive with conventional power systems. The most promising engine candidates are Stirling, high temperature Brayton, and combined cycle. Engines available in the current market today do not meet these requirements. The development of Stirling and high temperature Brayton for automotive applications was studied which utilizes much of the technology developed in this automotive program for solar power engines. The technical status of the engine candidates is reviewed and the components that may additional development to meet solar thermal system requirements are identified.

Status of the Body of Knowledge and Curriculum to Advance Systems Engineering (BKCASE (trademark)) Project

DTIC Science & Technology

2011-10-01

Systems engineer- ing knowledge has also been documented through the standards bodies, most notably : • ISO /IEC/IEEE 15288, Systems Engineer- ing...System Life Cycle Processes, 2008 (see [10]). • ANSI/EIA 632, Processes for Engineering a System, (1998) • IEEE 1220, ISO /IEC 26702 Application...tion • United States Defense Acquisition Guidebook, Chapter 4, June 27, 2011 • IEEE/EIA 12207 , Software Life Cycle Processes, 2008 • United

THE ENGINES BEHIND SUPERNOVAE AND GAMMA-RAY BURSTS

DOE Office of Scientific and Technical Information (OSTI.GOV)

FRYER, CHRISTOPHER LEE

2007-01-23

The authors review the different engines behind supernova (SNe) and gamma-ray bursts (GRBs), focusing on those engines driving explosions in massive stars: core-collapse SNe and long-duration GRBs. Convection and rotation play important roles in the engines of both these explosions. They outline the basic physics and discuss the wide variety of ways scientists have proposed that this physics can affect the supernova explosion mechanism, concluding with a review of the current status in these fields.

Status of the Magma Energy Project

NASA Astrophysics Data System (ADS)

Dunn, J. C.

The current magma energy project is assessing the engineering feasibility of extracting thermal energy directly from crustal magma bodies. The estimated size of the U.S. resource (50,000 to 500,000 quads) suggests a considerable potential impact on future power generation. In a previous seven-year study, we concluded that there are no insurmountable barriers that would invalidate the magma energy concept. Several concepts for drilling, energy extraction, and materials survivability were successfully demonstrated in Kilauea Iki lava lake, Hawaii. The present program is addressing the engineering design problems associated with accessing magma bodies and extracting thermal energy for power generation. The normal stages for development of a geothermal resource are being investigated: exploration, drilling and completions, production, and surface power plant design. Current status of the engineering program and future plans are described.

The energy efficient engine project

NASA Technical Reports Server (NTRS)

Macioce, L. E.; Schaefer, J. W.; Saunders, N. T.

1980-01-01

The Energy Efficient Engine Project is directed at providing, by 1984, the advanced technologies which could be used for a generation of fuel conservative turbofan engines. The project is conducted through contracts with the General Electric Company and Pratt and Whitney Aircraft. The scope of the entire project and the current status of these efforts are summarized. A description of the preliminary designs of the fully developed engines is included and the potential benefits of these advanced engines, as well as highlights of some of the component technology efforts conducted to date, are discussed.

Gas turbine engines and transmissions for bus demonstration programs. Technical status report, 31 October 1979-31 January 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nigro, D.N.

1980-02-01

Progress is reported on the procurement and delivery of 11 Allison GT 404-4 Industrial Gas Turbine Engines and 5 HT740CT and 6 V730CT Allison Automatic Transmissions for the Greyhound and Transit Coaches, respectively. Ceramic regenerators have been incorporated in the build configuration for last 4 Transit Coach engines. The 5 Greyhound Coach engines and the first 2 Transit Coach engines were built in the all-metal configuration. The Master Schedules for the program are presented.

Done in 60 seconds- See a Massive Rocket Fuel Tank Built in A Minute

NASA Image and Video Library

2016-08-18

The 7.5-minute test conducted at NASA’s Stennis Space Center is part of a series of tests designed to put the upgraded former space shuttle engines through the rigorous temperature and pressure conditions they will experience during a launch. The tests also support the development of a new controller, or “brain,” for the engine, which monitors engine status and communicates between the rocket and the engine, relaying commands to the engine and transmitting data back to the rocket.

Gas-heat-pump development

NASA Astrophysics Data System (ADS)

Creswick, F. A.

Incentives for the development of gas heat pumps are discussed. Technical progress made on several promising technologies was reviewed. The status of development of gas-engine-driven heat pumps, the absorption cycle for the near- and long-term gas heat pump systems, the Stirling engine, the small Rankine-cycle engines, and gas-turbine-driven heat pump systems were briefly reviewed. Progress in the US, Japan, and Europe is noted.

Women in Engineering--Beyond Recruitment. Proceedings of the Conference (Cornell University, Ithaca, New York, June 22-25, 1975).

ERIC Educational Resources Information Center

Ott, Mary Diederich, Ed.; Reese, Nancy A., Ed.

This report contains invited papers and comments from a conference on the status and problems of women in engineering. First, a discussion of research reveals that most women choose engineering as a field for college study late in their secondary education, depend heavily on external sources of support, and have attitudes and experiences different…

Status, Vision, and Challenges of an Intelligent Distributed Engine Control Architecture (Postprint)

DTIC Science & Technology

2007-09-18

TERMS turbine engine control, engine health management, FADEC , Universal FADEC , Distributed Controls, UF, UF Platform, common FADEC , Generic FADEC ...Modular FADEC , Adaptive Control 16. SECURITY CLASSIFICATION OF: 19a. NAME OF RESPONSIBLE PERSON (Monitor) a. REPORT Unclassified b. ABSTRACT...Eventually the Full Authority Digital Electronic Control ( FADEC ) became the norm. Presently, this control system architecture accounts for 15 to 20% of

E-4 Test Facility Design Status

NASA Technical Reports Server (NTRS)

Ryan, Harry; Canady, Randy; Sewell, Dale; Rahman, Shamim; Gilbrech, Rick

2001-01-01

Combined-cycle propulsion technology is a strong candidate for meeting NASA space transportation goals. Extensive ground testing of integrated air-breathing/rocket system (e.g., components, subsystems and engine systems) across all propulsion operational modes (e.g., ramjet, scramjet) will be needed to demonstrate this propulsion technology. Ground testing will occur at various test centers based on each center's expertise. Testing at the NASA John C. Stennis Space Center will be primarily concentrated on combined-cycle power pack and engine systems at sea level conditions at a dedicated test facility, E-4. This paper highlights the status of the SSC E-4 test Facility design.

Women Scientists and Engineers: Trends in Participation.

ERIC Educational Resources Information Center

Vetter, Betty M.

1981-01-01

Examines trends in participation of women in science and engineering over the past decade and estimates changes during the 1980s. Focuses on educational attainment, employment status and sector, and salaries, and indicates a gap in salaries and career opportunities between men and women. (JN)

DOT/NASA comparative assessment of Brayton engines for guideway vehicles and busses. Volume 2: Analysis and results

NASA Technical Reports Server (NTRS)

1975-01-01

Gas turbine engines were assessed for application to hear duty transportation. A summary of the assumptions, applications, and methods of analysis is included along with a discussion of the approach taken, the technical program flow chart, and weighting criteria used for performance evaluation. The various engines are compared on the bases of weight, performance, emissions and noise, technology status, and growth potential. The results of the engine screening phase and the conceptual design phase are presented.

A bill to amend the Federal Food, Drug, and Cosmetic Act to require labeling of genetically engineered fish.

THOMAS, 113th Congress

Sen. Begich, Mark [D-AK

2013-02-07

Senate - 02/07/2013 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

A bill to amend the Federal Food, Drug, and Cosmetic Act to prevent the approval of genetically-engineered fish.

THOMAS, 111th Congress

Sen. Begich, Mark [D-AK

2010-11-18

Senate - 11/18/2010 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

A bill to amend the Federal Food, Drug, and Cosmetic Act to require labeling of genetically-engineered fish.

THOMAS, 111th Congress

Sen. Begich, Mark [D-AK

2010-11-18

Senate - 11/18/2010 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

A bill to amend the Federal Food, Drug, and Cosmetic Act to prevent the approval of genetically-engineered fish.

THOMAS, 112th Congress

Sen. Begich, Mark [D-AK

2011-01-31

Senate - 01/31/2011 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

A resolution supporting the goals and ideals of National Engineers Week, and for other purposes.

THOMAS, 111th Congress

Sen. Kaufman, Edward E. [D-DE

2010-02-11

Senate - 02/23/2010 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

A bill to amend the Federal Food, Drug, and Cosmetic Act to require labeling of genetically-engineered fish.

THOMAS, 112th Congress

Sen. Begich, Mark [D-AK

2011-01-31

Senate - 01/31/2011 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

A resolution expressing support for the inaugural USA Science & Engineering Festival.

THOMAS, 111th Congress

Sen. Kaufman, Edward E. [D-DE

2010-09-28

Senate - 09/28/2010 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

Software development environments: Status and trends

NASA Technical Reports Server (NTRS)

Duffel, Larry E.

1988-01-01

Currently software engineers are the essential integrating factors tying several components together. The components consist of process, methods, computers, tools, support environments, and software engineers. The engineers today empower the tools versus the tools empowering the engineers. Some of the issues in software engineering are quality, managing the software engineering process, and productivity. A strategy to accomplish this is to promote the evolution of software engineering from an ad hoc, labor intensive activity to a managed, technology supported discipline. This strategy may be implemented by putting the process under management control, adopting appropriate methods, inserting the technology that provides automated support for the process and methods, collecting automated tools into an integrated environment and educating the personnel.

Towards systems metabolic engineering of microorganisms for amino acid production.

PubMed

Park, Jin Hwan; Lee, Sang Yup

2008-10-01

Microorganisms capable of efficient production of amino acids have traditionally been developed by random mutation and selection method, which might cause unwanted physiological changes in cellular metabolism. Rational genome-wide metabolic engineering based on systems and synthetic biology tools, which is termed 'systems metabolic engineering', is rising as an alternative to overcome these problems. Recently, several amino acid producers have been successfully developed by systems metabolic engineering, where the metabolic engineering procedures were performed within a systems biology framework, and entire metabolic networks, including complex regulatory circuits, were engineered in an integrated manner. Here we review the current status of systems metabolic engineering successfully applied for developing amino acid producing strains and discuss future prospects.

A review and forecast of engine system research at the Army Propulsion Directorate

NASA Technical Reports Server (NTRS)

Bobula, George A.

1989-01-01

An account is given of the development status and achievements to date of the U.S. Army Propulsion Directorate's Small Turbine Engine Research (STER) programs, which are experimental investigations of the physics of entire engine systems from the viewpoints of component interactions and/or system dynamics. STER efforts are oriented toward the evaluation of complete turboshaft engine advanced concepts and are conducted at the ECRL-2 indoor, sea-level engine test facility. Attention is given to the results obtained by STER experiments concerned with IR-suppressing engine exhausts, a ceramic turbine-blade shroud, an active shaft-vibration control system, and a ceramic-matrix combustor liner.

Development Status of the NASA MC-1 (Fastrac) Engine

NASA Technical Reports Server (NTRS)

Ballard, Richard O.; Olive, Tim; Turner, James E. (Technical Monitor)

2000-01-01

The MC-1 (formerly known as the Fastrac 60K) Engine is being developed for the X-34 technology demonstrator vehicle. It is a pump-fed liquid rocket engine with fixed thrust operating at one rated power level of 60,000 lbf vacuum thrust using a 15:1 area ratio nozzle (slightly higher for the 30:1 flight nozzle). Engine system development testing of the MC-1 has been ongoing since 24 Oct 1998. To date, 48 tests have been conducted on three engines using three separate test stands. This paper will provide some details of the engine, the tests conducted, and the lessons learned to date.

14 CFR 125.226 - Digital flight data recorders.

Code of Federal Regulations, 2014 CFR

2014-01-01

... this section, no person may operate under this part a turbine-engine-powered transport category... selection; (37) Drift angle (when an information source is installed); (38) Wind speed and direction (when... rudder valve status. (b) For all turbine-engine powered transport category airplanes manufactured on or...

14 CFR 125.226 - Digital flight data recorders.

Code of Federal Regulations, 2010 CFR

2010-01-01

... this section, no person may operate under this part a turbine-engine-powered transport category... selection; (37) Drift angle (when an information source is installed); (38) Wind speed and direction (when... rudder valve status. (b) For all turbine-engine powered transport category airplanes manufactured on or...

14 CFR 125.226 - Digital flight data recorders.

Code of Federal Regulations, 2013 CFR

2013-01-01

... this section, no person may operate under this part a turbine-engine-powered transport category... selection; (37) Drift angle (when an information source is installed); (38) Wind speed and direction (when... rudder valve status. (b) For all turbine-engine powered transport category airplanes manufactured on or...

14 CFR 125.226 - Digital flight data recorders.

Code of Federal Regulations, 2012 CFR

2012-01-01

... this section, no person may operate under this part a turbine-engine-powered transport category... selection; (37) Drift angle (when an information source is installed); (38) Wind speed and direction (when... rudder valve status. (b) For all turbine-engine powered transport category airplanes manufactured on or...

14 CFR 125.226 - Digital flight data recorders.

Code of Federal Regulations, 2011 CFR

2011-01-01

... this section, no person may operate under this part a turbine-engine-powered transport category... selection; (37) Drift angle (when an information source is installed); (38) Wind speed and direction (when... rudder valve status. (b) For all turbine-engine powered transport category airplanes manufactured on or...

Status and summary of laser energy conversion. [for space power transmission systems

NASA Technical Reports Server (NTRS)

Lee, G.

1978-01-01

This paper presents a survey of the status of laser energy converters. Since the inception of these devices in the early 1970's, significant advances have been made in understanding the basic conversion processes. Numerous theoretical and experimental studies have indicated that laser energy can be converted at wavelengths from the ultraviolet to the far-infrared. These converters can be classified into five general categories: photovoltaics, heat engines, thermoelectronic, optical diode, and photochemical. The conversion can be directly into electricity (such as the photovoltaic, thermoelectronic, and optical diode) or it can go through an intermediate stage of conversion to mechanical energy, as in the heat engines. The photochemical converters result in storable energy such as hydrogen. Projected conversion efficiencies range from about 30% for the photochemical to nearly 75% for the heat engines.

Constructing engineers through practice: Gendered features of learning and identity development

NASA Astrophysics Data System (ADS)

Tonso, Karen L.

How do women and men student engineers develop an engineering identity (a sense of belonging, or not), while practicing "actual" engineering? What are the influences of gender, learning and knowledge, relations of power, and conceptions of equality on cultural identity development? I studied these issues in reform-minded engineering design classes, courses organized around teaching students communications, teamwork, and practical engineering. Engineering-student cultural identity categories revealed a status hierarchy, predicated on meeting "academic" criteria for excellence, and the almost total exclusion of women. While working as an engineering colleague on five student teams (three first-year and two senior) and attending their design classes, I documented how cultural identities were made evident and constructed in students' practical engineering. Design projects promoted linking academic knowledge with real-world situations, sharing responsibilities and trusting colleagues, communicating engineering knowledge to technical and non-technical members of business communities, and addressing gaps in students' knowledge. With a curriculum analysis and survey of students' perceptions of the differences between design and conventional courses, I embedded the design classes in the wider campus and found that: (1) Engineering education conferred prestige, power, and well-paying jobs on students who performed "academic" engineering, while failing to adequately encourage "actual" engineering practices. High-status student engineers were the least likely to perform "actual" engineering in design teams. (2) Engineering education advanced an ideology that encouraged its practitioners to consider men's privilege and women's invisibility normal. By making "acting like men act" the standards to which engineering students must conform, women learned to put up with oppressive treatment. Women's accepting their own mistreatment and hiding their womanhood became a condition of women's belonging. (3) Despite all of the pressures to do otherwise, (some) teams of students (at all levels) carved out small oases where "actual" engineering prevailed and women's participation was robust. Students--not faculty, not progressive pedagogy, not "reformed" courses--disrupted prevailing norms. However, two women engineering students, one on each senior team, performed fabulous "actual" engineering, yet neither of them had a job when they graduated--the only two senior students on my teams without jobs.

NASA/DOE automotive Stirling engine project: Overview 1986

NASA Technical Reports Server (NTRS)

Beremand, D. G.; Shaltens, R. K.

1986-01-01

The DOE/NASA Automotive Stirling Engine Project is reviewed and its technical progress and status are presented. Key technologies in materials, seals, and piston rings are progressing well. Seven first-generation engines, and modifications thereto, have accumulated over 15,000 hr of test time, including 1100hr of in-vehicle testing. Results indicate good progress toward the program goals. The first second-generation engine is now undergoing initial testing. It is expected that the program goal of a 30-percent improvement in fuel economy will be achieved in tests of a second-generation engine in a Celebrity vehicle.

Status of NASA aircraft engine emission reduction and upper atmosphere measurement programs

NASA Technical Reports Server (NTRS)

Rudey, R. A.; Lezberg, E. A.

1976-01-01

Advanced emission reduction techniques for five existing aircraft gas turbine engines are evaluated. Progress made toward meeting the 1979 EPA standards in rig tests of combustors for the five engines is reported. Results of fundamental combustion studies suggest the possibility of a new generation of jet engine combustor technology that would reduce oxides-of-nitrogen (NOx) emissions far below levels currently demonstrated in the engine-related programs. The Global Air Sampling Program (GAS) is now in full operation and is providing data on constituent measurements of ozone and other minor upper-atmosphere species related to aircraft emissions.

DOE/NASA automotive Stirling engine project - Overview 86

NASA Technical Reports Server (NTRS)

Beremand, D. G.; Shaltens, R. K.

1986-01-01

The DOE/NASA Automotive Stirling Engine Project is reviewed and its technical progress and status are presented. Key technologies in materials, seals, and piston rings are progressing well. Seven first-generation engines, and modifications thereto, have accumulated over 15,000 hr of test time, including 1100 hr of in-vehicle testing. Results indicate good progress toward the program goals. The first second-generation engine is now undergoing initial testing. It is expected that the program goal of a 30-percent improvement in fuel economy will be achieved in tests of a second-generation engine in a Celebrity vehicle.

Electroacupuncture and splinting versus splinting alone to treat carpal tunnel syndrome: a randomized controlled trial.

PubMed

Chung, Vincent C H; Ho, Robin S T; Liu, Siya; Chong, Marc K C; Leung, Albert W N; Yip, Benjamin H K; Griffiths, Sian M; Zee, Benny C Y; Wu, Justin C Y; Sit, Regina W S; Lau, Alexander Y L; Wong, Samuel Y S

2016-09-06

The effectiveness of acupuncture for managing carpal tunnel syndrome is uncertain, particularly in patients already receiving conventional treatments (e.g., splinting). We aimed to assess the effects of electroacupuncture combined with splinting. We conducted a randomized parallel-group assessor-blinded 2-arm trial on patients with clinically diagnosed primary carpal tunnel syndrome. The treatment group was offered 13 sessions of electroacupuncture over 17 weeks. The treatment and control groups both received continuous nocturnal wrist splinting. Of 181 participants randomly assigned to electroacupuncture combined with splinting (n = 90) or splinting alone (n = 91), 174 (96.1%) completed all follow-up. The electroacupuncture group showed greater improvements at 17 weeks in symptoms (primary outcome of Symptom Severity Scale score mean difference [MD] -0.20, 95% confidence interval [CI] -0.36 to -0.03), disability (Disability of Arm, Shoulder and Hand Questionnaire score MD -6.72, 95% CI -10.9 to -2.57), function (Functional Status Scale score MD -0.22, 95% CI -0.38 to -0.05), dexterity (time to complete blinded pick-up test MD -6.13 seconds, 95% CI -10.6 to -1.63) and maximal tip pinch strength (MD 1.17 lb, 95% CI 0.48 to 1.86). Differences between groups were small and clinically unimportant for reduction in pain (numerical rating scale -0.70, 95% CI -1.34 to -0.06), and not significant for sensation (first finger monofilament test -0.08 mm, 95% CI -0.22 to 0.06). For patients with primary carpal tunnel syndrome, chronic mild to moderate symptoms and no indication for surgery, electroacupuncture produces small changes in symptoms, disability, function, dexterity and pinch strength when added to nocturnal splinting. Chinese Clinical Trial Register no. ChiCTR-TRC-11001655 (www.chictr.org.cn/showprojen.aspx?proj=7890); subsequently deposited in the World Health Organization International Clinical Trials Registry Platform (apps.who.int/trialsearch/Trial2.aspx?TrialID=ChiCTR-TRC-11001655). © 2016 Canadian Medical Association or its licensors.

Disparities in infant hospitalizations in Indigenous and non-Indigenous populations in Quebec, Canada.

PubMed

He, Hua; Xiao, Lin; Torrie, Jill Elaine; Auger, Nathalie; McHugh, Nancy Gros-Louis; Zoungrana, Hamado; Luo, Zhong-Cheng

2017-05-29

Infant mortality is higher in Indigenous than non-Indigenous populations, but comparable data on infant morbidity are lacking in Canada. We evaluated disparities in infant morbidities experienced by Indigenous populations in Canada. We used linked population-based birth and health administrative data from Quebec, Canada, to compare hospitalization rates, an indicator of severe morbidity, in First Nations, Inuit and non-Indigenous singleton infants (< 1 year) born between 1996 and 2010. Our cohort included 19 770 First Nations, 3930 Inuit and 225 380 non-Indigenous infants. Compared with non-Indigenous infants, all-cause hospitalization rates were higher in First Nations infants (unadjusted risk ratio [RR] 2.05, 95% confidence interval [CI] 1.99-2.11; fully adjusted RR 1.43, 95% CI 1.37-1.50) and in Inuit infants (unadjusted RR 1.96, 95% CI 1.87-2.05; fully adjusted RR 1.37, 95% CI 1.24-1.52). Higher risks of hospitalization (accounting for multiple comparisons) were observed for First Nations infants in 12 of 16 disease categories and for Inuit infants in 7 of 16 disease categories. Maternal characteristics (age, education, marital status, parity, rural residence and Northern residence) partly explained the risk elevations, but maternal chronic illnesses and gestational complications had negligible influence overall. Acute bronchiolitis (risk difference v. non-Indigenous infants, First Nations 37.0 per 1000, Inuit 39.6 per 1000) and pneumonia (risk difference v. non-Indigenous infants, First Nations 41.2 per 1000, Inuit 61.3 per 1000) were the 2 leading causes of excess hospitalizations in Indigenous infants. First Nations and Inuit infants had substantially elevated burdens of hospitalizations as a result of diseases of multiple systems. The findings identify substantial unmet needs in disease prevention and medical care for Indigenous infants. © 2017 Canadian Medical Association or its licensors.

Influences on the start, selection and duration of treatment with antibiotics in long-term care facilities.

PubMed

Daneman, Nick; Campitelli, Michael A; Giannakeas, Vasily; Morris, Andrew M; Bell, Chaim M; Maxwell, Colleen J; Jeffs, Lianne; Austin, Peter C; Bronskill, Susan E

2017-06-26

Understanding the extent to which current antibiotic prescribing behaviour is influenced by clinicians' historical patterns of practice will help target interventions to optimize antibiotic use in long-term care. Our objective was to evaluate whether clinicians' historical prescribing behaviours influence the start, prolongation and class selection for treatment with antibiotics in residents of long-term care facilities. We conducted a retrospective cohort study of all physicians who prescribed to residents in long-term care facilities in Ontario between Jan. 1 and Dec. 31, 2014. We examined variability in antibiotic prescribing among physicians for 3 measures: start of treatment with antibiotics, use of prolonged durations exceeding 7 days and selection of fluoroquinolones. Funnel plots with control limits were used to determine the extent of variation and characterize physicians as extreme low, low, average, high and extreme high prescribers for each tendency. Multivariable logistic regression was used to assess whether a clinician's prescribing tendency in the previous year predicted current prescribing patterns, after accounting for residents' demographics, comorbidity, functional status and indwelling devices. Among 1695 long-term care physicians, who prescribed for 93 132 residents, there was wide variability in the start of antibiotic treatment (median 45% of patients, interquartile range [IQR] 32%-55%), use of prolonged treatment durations (median 30% of antibiotic prescriptions, IQR 19%-46%) and selection of fluoroquinolones (median 27% of antibiotic prescriptions, IQR 18%-37%). Prescribing tendencies for antibiotics by physicians in 2014 correlated strongly with tendencies in the previous year. After controlling for individual resident characteristics, prior prescribing tendency was a significant predictor of current practice. Physicians prescribing antibiotics exhibited individual, measurable and historical tendencies toward start of antibiotic treatment, use of prolonged treatment duration and class selection. Prescriber audit and feedback may be a promising tool to optimize antibiotic use in long-term care facilities. © 2017 Canadian Medical Association or its licensors.

Perinatal suicide in Ontario, Canada: a 15-year population-based study.

PubMed

Grigoriadis, Sophie; Wilton, Andrew S; Kurdyak, Paul A; Rhodes, Anne E; VonderPorten, Emily H; Levitt, Anthony; Cheung, Amy; Vigod, Simone N

2017-08-28

Death by suicide during the perinatal period has been understudied in Canada. We examined the epidemiology of and health service use related to suicides during pregnancy and the first postpartum year. In this retrospective, population-based cohort study, we linked health administrative databases with coroner death records (1994-2008) for Ontario, Canada. We compared sociodemographic characteristics, clinical features and health service use in the 30 days and 1 year before death between women who died by suicide perinatally, women who died by suicide outside of the perinatal period and living perinatal women. The perinatal suicide rate was 2.58 per 100 000 live births, with suicide accounting for 51 (5.3%) of 966 perinatal deaths. Most suicides occurred during the final quarter of the first postpartum year, with highest rates in rural and remote regions. Perinatal women were more likely to die from hanging (33.3% [17/51]) or jumping or falling (19.6% [10/51]) than women who died by suicide non-perinatally ( p = 0.04). Only 39.2% (20/51) had mental health contact within the 30 days before death, similar to the rate among those who died by suicide non-perinatally (47.7% [762/1597]; odds ratio [OR] 0.71, 95% confidence interval [CI] 0.40-1.25). Compared with living perinatal women matched by pregnancy or postpartum status at date of suicide, perinatal women who died by suicide had similar likelihood of non-mental health primary care and obstetric care before the index date but had a lower likelihood of pediatric contact (64.5% [20/31] v. 88.4% [137/155] at 30 days; OR 0.24, 95% CI 0.10-0.58). The perinatal suicide rate for Ontario during the period 1994-2008 was comparable to international estimates and represents a substantial component of Canadian perinatal mortality. Given that deaths by suicide occur throughout the perinatal period, all health care providers must be collectively vigilant in assessing risk. © 2017 Canadian Medical Association or its licensors.

Job insecurity and risk of diabetes: a meta-analysis of individual participant data.

PubMed

Ferrie, Jane E; Virtanen, Marianna; Jokela, Markus; Madsen, Ida E H; Heikkilä, Katriina; Alfredsson, Lars; Batty, G David; Bjorner, Jakob B; Borritz, Marianne; Burr, Hermann; Dragano, Nico; Elovainio, Marko; Fransson, Eleonor I; Knutsson, Anders; Koskenvuo, Markku; Koskinen, Aki; Kouvonen, Anne; Kumari, Meena; Nielsen, Martin L; Nordin, Maria; Oksanen, Tuula; Pahkin, Krista; Pejtersen, Jan H; Pentti, Jaana; Salo, Paula; Shipley, Martin J; Suominen, Sakari B; Tabák, Adam; Theorell, Töres; Väänänen, Ari; Vahtera, Jussi; Westerholm, Peter J M; Westerlund, Hugo; Rugulies, Reiner; Nyberg, Solja T; Kivimäki, Mika

2016-12-06

Job insecurity has been associated with certain health outcomes. We examined the role of job insecurity as a risk factor for incident diabetes. We used individual participant data from 8 cohort studies identified in 2 open-access data archives and 11 cohort studies participating in the Individual-Participant-Data Meta-analysis in Working Populations Consortium. We calculated study-specific estimates of the association between job insecurity reported at baseline and incident diabetes over the follow-up period. We pooled the estimates in a meta-analysis to produce a summary risk estimate. The 19 studies involved 140 825 participants from Australia, Europe and the United States, with a mean follow-up of 9.4 years and 3954 incident cases of diabetes. In the preliminary analysis adjusted for age and sex, high job insecurity was associated with an increased risk of incident diabetes compared with low job insecurity (adjusted odds ratio [OR] 1.19, 95% confidence interval [CI] 1.09-1.30). In the multivariable-adjusted analysis restricted to 15 studies with baseline data for all covariates (age, sex, socioeconomic status, obesity, physical activity, alcohol and smoking), the association was slightly attenuated (adjusted OR 1.12, 95% CI 1.01-1.24). Heterogeneity between the studies was low to moderate (age- and sex-adjusted model: I 2 = 24%, p = 0.2; multivariable-adjusted model: I 2 = 27%, p = 0.2). In the multivariable-adjusted analysis restricted to high-quality studies, in which the diabetes diagnosis was ascertained from electronic medical records or clinical examination, the association was similar to that in the main analysis (adjusted OR 1.19, 95% CI 1.04-1.35). Our findings suggest that self-reported job insecurity is associated with a modest increased risk of incident diabetes. Health care personnel should be aware of this association among workers reporting job insecurity. © 2016 Canadian Medical Association or its licensors.

Electronic cigarette use and smoking initiation among youth: a longitudinal cohort study.

PubMed

Hammond, David; Reid, Jessica L; Cole, Adam G; Leatherdale, Scott T

2017-10-30

The influence of e-cigarette use on smoking initiation is a highly controversial issue, with limited longitudinal data available for examining temporal associations. We examined e-cigarette use and its association with cigarette-smoking initiation at 1-year follow-up within a large cohort of Canadian secondary school students. We analyzed data from students in grades 9-12 who participated in 2 waves of COMPASS, a cohort study of purposefully sampled secondary schools in Ontario and Alberta, Canada, at baseline (2013/14) and 1-year follow-up (2014/15). We assessed cigarette smoking and e-cigarette use at baseline and follow-up using self-completed surveys. We used generalized linear mixed-effects models to examine correlates of past 30-day e-cigarette use at baseline and smoking initiation between waves within the longitudinal sample. Past 30-day e-cigarette use increased from 2013/14 to 2014/15 (7.2% v. 9.7%, p < 0.001), whereas past 30-day cigarette smoking decreased slightly (11.4% v. 10.8%, p = 0.02). Among the 44 163 students evaluated at baseline, past 30-day e-cigarette use was strongly associated with smoking status and smoking susceptibility. In the longitudinal sample ( n = 19 130), past 30-day use of e-cigarettes at baseline was associated with initiation of smoking a whole cigarette (adjusted odds ratio [OR] 2.12, 95% confidence interval [CI] 1.68-2.66) and with initiation of daily smoking (adjusted OR 1.79, 95% CI 1.41-2.28) at follow-up. E-cigarette use was strongly associated with cigarette smoking behaviour, including smoking initiation at follow-up. The causal nature of this association remains unclear, because common factors underlying the use of both e-cigarettes and conventional cigarettes may also account for the temporal order of initiation. © 2017 Joule Inc. or its licensors.

Realization of entry-to-practice milestones by Canadians who studied medicine abroad and other international medical graduates: a retrospective cohort study.

PubMed

Mathews, Maria; Kandar, Rima; Slade, Steve; Yi, Yanqing; Beardall, Sue; Bourgeault, Ivy

2017-06-19

International medical graduates must realize a series of milestones to obtain full licensure. We examined the realization of milestones by Canadian and non-Canadian graduates of Western or Caribbean medical schools, and Canadian and non-Canadian graduates from other medical schools. Using the National IMG Database (data available for 2005-2011), we created 2 cohorts: 1) international medical graduates who had passed the Medical Council of Canada Qualifying Examination Part I between 2005 and 2010 and 2) those who had first entered a family medicine postgraduate program between 2005 and 2009, or had first entered a specialty postgraduate program in 2005 or 2006. We examined 3 entry-to-practice milestones; obtaining a postgraduate position, passing the Medical Council of Canada Qualifying Examination Part II and obtaining a specialty designation. Of the 6925 eligible graduates in cohort 1, 2144 (31.0%) had obtained a postgraduate position. Of the 1214 eligible graduates in cohort 2, 1126 (92.8%) had passed the Qualifying Examination Part II, and 889 (73.2%) had obtained a specialty designation. In multivariate analyses, Canadian graduates of Western or Caribbean medical schools (odds ratio [OR] 4.69, 95% confidence interval [CI] 3.82-5.71) and Canadian graduates of other medical schools (OR 1.49, 95% CI 1.31-1.70) were more likely to obtain a postgraduate position than non-Canadian graduates of other (not Western or Caribbean) medical schools. There was no difference among the groups in passing the Qualifying Examination Part II or obtaining a specialty designation. Canadians who studied abroad were more likely than other international medical graduates to obtain a postgraduate position; there were no differences among the groups in realizing milestones once in a postgraduate program. These findings support policies that do not distinguish postgraduate applicants by citizenship or permanent residency status before medical school. Copyright 2017, Joule Inc. or its licensors.

Incidence of psychotic disorders among first-generation immigrants and refugees in Ontario.

PubMed

Anderson, Kelly K; Cheng, Joyce; Susser, Ezra; McKenzie, Kwame J; Kurdyak, Paul

2015-06-16

Evidence suggests that migrant groups have an increased risk of psychotic disorders and that the level of risk varies by country of origin and host country. Canadian evidence is lacking on the incidence of psychotic disorders among migrants. We sought to examine the incidence of schizophrenia and schizoaffective disorders in first-generation immigrants and refugees in the province of Ontario, relative to the general population. We constructed a retrospective cohort that included people aged 14-40 years residing in Ontario as of Apr. 1, 1999. Population-based administrative data from physician billings and hospital admissions were linked to data from Citizenship and Immigration Canada. We used Poisson regression models to calculate age- and sex-adjusted incidence rate ratios (IRRs) and 95% confidence intervals (CIs) for immigrant and refugee groups over a 10-year period. In our cohort (n = 4,284,694), we found higher rates of psychotic disorders among immigrants from the Caribbean and Bermuda (IRR 1.60, 95% CI 1.29-1.98). Lower rates were found among immigrants from northern Europe (IRR 0.50, 95% CI 0.28-0.91), southern Europe (IRR 0.60, 95% CI 0.41-0.90) and East Asia (IRR 0.56, 95% CI 0.41-0.78). Refugee status was an independent predictor of risk among all migrants (IRR 1.27, 95% CI 1.04-1.56), and higher rates were found specifically for refugees from East Africa (IRR 1.95, 95% CI 1.44-2.65) and South Asia (IRR 1.51, 95% CI 1.08-2.12). The differential pattern of risk across ethnic subgroups in Ontario suggests that psychosocial and cultural factors associated with migration may contribute to the risk of psychotic disorders. Some groups may be more at risk, whereas others are protected. © 2015 Canadian Medical Association or its licensors.

Elements of Motivational Structure for Studying Mechanical Engineering

ERIC Educational Resources Information Center

Dubreta, Nikša; Miloš, Damir

2017-01-01

The article presents the findings on students' reasons for studying mechanical engineering. These reasons were covered in terms of extrinsic and intrinsic motivation additionally related to selected independent variables of the sample--students' secondary school Grade Point Average, their gender and the socio-economic status. The research was…

15th Railroad Engineering Conference Proceedings, Railroad R&D Challenges of the 80's : Opportunities & Obstacles

DOT National Transportation Integrated Search

1980-06-01

This report constitutes the proceedings of the 15th Railroad Engineering Conference held at TSC on October 21-23, 1979. Conference papers were delivered by various industry and Government officials and centered on three topic areas: The Status of the...

Engineering Technology Careers; Career Guidance Information for Engineering Technicians. Publication No. 1065.

ERIC Educational Resources Information Center

National Council of Technical Schools, Washington, DC.

Prepared by the National Council of Technical Schools, this reference may be used by prospective students , their parents, and counselors in learning the philosophy and objectives, historical background, and present status of technical schools and career opportunities as a technician. Career opportunities included are: (1) Aerospace/Aviation…

78 FR 51706 - Bayer CropScience LP; Determination of Nonregulated Status of Soybean Genetically Engineered for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-21

... Soybean Genetically Engineered for Herbicide Resistance AGENCY: Animal and Plant Health Inspection Service... for resistance to the herbicides glyphosate and isoxaflutole, is no longer considered a regulated... for resistance to the herbicides glyphosate and isoxaflutole. The petition states that this soybean is...

77 FR 41358 - Bayer CropScience LP; Availability of Petition, Plant Pest Risk Assessment, and Environmental...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... for Determination of Nonregulated Status of Soybean Genetically Engineered for Herbicide Tolerance... genetically engineered for resistance to the herbicides glyphosate and isoxaflutole. The petition has been... herbicides glyphosate and isoxaflutole. The petition states that this soybean is unlikely to pose a plant...

Leadership Training in Science, Technology, Engineering and Mathematics Education in Bulgaria

ERIC Educational Resources Information Center

Bairaktarova, Diana; Cox, Monica F.; Evangelou, Demetra

2011-01-01

This synthesis paper explores current leadership training in science, technology, engineering and mathematics (STEM) education in Bulgaria. The analysis begins with discussion of global factors influencing the implementation of leadership training in STEM education in general and then presents information about the current status of leadership…

Scientists, Engineers, and Physicians From Abroad, Trends Through Fiscal Year 1970.

ERIC Educational Resources Information Center

Gannon, Joseph; Stewart, Christine C.

A report on the influx of scientists, engineers, and physicians from abroad is presented to assess recent trends in terms of numbers, occupations, and national backgrounds. Both immigrant and nonimmigrant components are included. Descriptions are made in connection with migration patterns, aliens adjusted to immigrant status, demographic…

Human Factors and Robotics: Current Status and Future Prospects.

ERIC Educational Resources Information Center

Parsons, H. McIlvaine; Kearsley, Greg P.

The principal human factors engineering issue in robotics is the division of labor between automation (robots) and human beings. This issue reflects a prime human factors engineering consideration in systems design--what equipment should do and what operators and maintainers should do. Understanding of capabilities and limitations of robots and…

Bacteria engineered for fuel ethanol production: current status

Treesearch

B.S. Dien; M.A. Cotta; T.W. Jeffries

2003-01-01

The lack of industrially suitable microorganisms for converting biomass into fuel ethanol has traditionally been cited as a major technical roadblock to developing a bioethanol industry. In the last two decades, numerous microorganisms have been engineered to selectively produce ethanol. Lignocellulosic biomass contains complex carbohydrates that necessitate utilizing...

Gas turbine engines and transmissions for bus demonstration programs. Technical status report, 30 April 1979-31 July 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nigro, D.N.

1979-07-01

The quarterly status report covers the period from 30 April 1979 through 31 July 1979 and is a summary of DDA activities for the effort performed on the procurement and delivery of eleven (11) Allison GT 404-4 gas turbine engines and five (5) HT740CT and six (6) V730CT Allison automatic transmissions and the required associated software. The contract requires the delivery of eleven (11) Allison GT 404-4 Industrial Gas Turbine Engines and five (5) HT740CT and six (6) V730CT Allison Automatic Transmissions for the Greyhound and Transit Coaches, respectively. In addition, software items such as cost reports, technical reports, installationmore » drawings, acceptance test data and parts lists are required. A recent decision by the DOE will modify the build configuration for the last four (4) Transit Coach engines. It was decided by the DOE at a meeting in Washington, DC on March 28, 1979 with representatives from DDA, NASA/LeRC, JPL and Booz-Allen and Hamilton that these engines will be built with ceramic regenerators. (TFD)« less

78 FR 37201 - Pioneer Hi-Bred International, Inc.; Determination of Nonregulated Status of Maize Genetically...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-20

... DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service [Docket No. APHIS-2012-0026] Pioneer Hi-Bred International, Inc.; Determination of Nonregulated Status of Maize Genetically Engineered for Herbicide and Insect Resistance AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION...

75 FR 32356 - Pioneer Hi-Bred International, Inc.; Determination of Nonregulated Status for Genetically...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-08

... DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service [Docket No. APHIS-2007-0156] Pioneer Hi-Bred International, Inc.; Determination of Nonregulated Status for Genetically Engineered High-oleic Soybeans AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Notice. SUMMARY: We are...

76 FR 60448 - Syngenta Biotechnology, Inc.; Determination of Nonregulated Status for Lepidopteran-Resistant Cotton

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-29

...] Syngenta Biotechnology, Inc.; Determination of Nonregulated Status for Lepidopteran-Resistant Cotton AGENCY... our determination that a cotton line developed by Syngenta Biotechnology, Inc., designated as event COT67B, which has been genetically engineered to express a protein to protect cotton plants from...

A resolution commending the encouragement of interest in science, technology, engineering, and mathematics by the entertainment industry, and for other purposes.

THOMAS, 111th Congress

Sen. Kaufman, Edward E. [D-DE

2010-09-15

Senate - 09/22/2010 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

A resolution congratulating the American Society of Mechanical Engineers on its 125 years of codes and standards development.

THOMAS, 111th Congress

Sen. Kaufman, Edward E. [D-DE

2009-06-09

Senate - 06/09/2009 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

14 CFR 91.417 - Maintenance records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... alteration and records of the 100-hour, annual, progressive, and other required or approved inspections, as... propeller, and each rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller... are required to be overhauled on a specified time basis. (iv) The current inspection status of the...

14 CFR 91.417 - Maintenance records.

Code of Federal Regulations, 2011 CFR

2011-01-01

... alteration and records of the 100-hour, annual, progressive, and other required or approved inspections, as... propeller, and each rotor. (ii) The current status of life-limited parts of each airframe, engine, propeller... are required to be overhauled on a specified time basis. (iv) The current inspection status of the...

76 FR 37767 - Pioneer Hi-Bred International, Inc.; Determination of Nonregulated Status for Corn Genetically...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-28

... DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service [Docket No. APHIS-2010-0041] Pioneer Hi-Bred International, Inc.; Determination of Nonregulated Status for Corn Genetically Engineered To Produce Male Sterile/Female Inbred Plants AGENCY: Animal and Plant Health Inspection Service, USDA...

Job Satisfaction of Academics: Reflections about Turkey

ERIC Educational Resources Information Center

Bilge, Filiz; Akman, Yasemin; Kelecioglu, Hulya

2007-01-01

The purpose of this study was to investigate the relationship of academics' job satisfaction to intrinsic and extrinsic factors such as gender, age, marital status, seniority, academic status, position, area of work (science and engineering, social science), and presence or absence of academic experience abroad. Participants included 203 academics…

Aircraft Energy Efficiency (ACEE) status report

NASA Technical Reports Server (NTRS)

Nored, D. L.; Dugan, J. F., Jr.; Saunders, N. T.; Ziemianski, J. A.

1979-01-01

Fuel efficiency in aeronautics, for fuel conservation in general as well as for its effect on commercial aircraft operating economics is considered. Projects of the Aircraft Energy Efficiency Program related to propulsion are emphasized. These include: (1) engine component improvement, directed at performance improvement and engine diagnostics for prolonged service life; (2) energy efficient engine, directed at proving the technology base for the next generation of turbofan engines; and (3) advanced turboprop, directed at advancing the technology of turboprop powered aircraft to a point suitable for commercial airline service. Progress in these technology areas is reported.

Network Analysis of Reconnaissance and Intrusion of an Industrial Control System

DTIC Science & Technology

2016-09-01

simulated a plant engineer using the engineering workstation web browser to authenticate to the vegetable cooker HMI. While the engineer established the...observed the vegetable cooker HMI web display, the attacker stopped capturing network traffic. Acting as the attacker, we searched the attacker’s pcap...manually controlled by human activity. In this testbed network, only web browser traffic (HTTP) is created by an operator to view an HMI status

The E3 combustors: Status and challenges. [energy efficient turbofan engines

NASA Technical Reports Server (NTRS)

Sokolowski, D. E.; Rohde, J. E.

1981-01-01

The design, fabrication, and initial testing of energy efficient engine combustors, developed for the next generation of turbofan engines for commercial aircraft, are described. The combustor designs utilize an annular configuration with two zone combustion for low emissions, advanced liners for improved durability, and short, curved-wall, dump prediffusers for compactness. Advanced cooling techniques and segmented construction characterize the advanced liners. Linear segments are made from castable, turbine-type materials.

Environmental engineering: A profession in transition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mackay, D.

1996-11-01

This 50th Industrial Waste Conference at Purdue gives one an opportunity and excuse to reflect on progress in Environmental Engineering and speculate on future changes. The author suggests that during this 50-year period Environmental Engineering has emerged as a discrete and creditable body of knowledge, practice, and academic study. In this review he presents a personal view of the evolution of Environmental Engineering and its present status. He also suggests some future directions and principles which may prove useful, especially in the academic world. The paper discusses the sphere of the environmental engineer, the social incentive, the academic curriculum, environmentalmore » engineers and society, the chlorine controversy, research, and the electronic revolution.« less

Leadership training in science, technology, engineering and mathematics education in Bulgaria

NASA Astrophysics Data System (ADS)

Bairaktarova, Diana; Cox, Monica F.; Evangelou, Demetra

2011-12-01

This synthesis paper explores current leadership training in science, technology, engineering and mathematics (STEM) education in Bulgaria. The analysis begins with discussion of global factors influencing the implementation of leadership training in STEM education in general and then presents information about the current status of leadership training in Bulgaria with emphases on the country's economics, politics and geographical location as specific factors influencing leadership education. A short background of Bulgaria is presented with regard to population, gross domestic product, educational system, engineering force and possible need for leaders in industry in Bulgaria and the European Union. The paper provides an overall view about the current status of leadership training in all Bulgarian universities offering STEM education and concentrates specifically on two major universities by examining their currently offered programmes. As part of the discussion, similar training elements in other European countries and the USA are presented.

Independent technical review, handbook

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

Purpose Provide an independent engineering review of the major projects being funded by the Department of Energy, Office of Environmental Restoration and Waste Management. The independent engineering review will address questions of whether the engineering practice is sufficiently developed to a point where a major project can be executed without significant technical problems. The independent review will focus on questions related to: (1) Adequacy of development of the technical base of understanding; (2) Status of development and availability of technology among the various alternatives; (3) Status and availability of the industrial infrastructure to support project design, equipment fabrication, facility construction,more » and process and program/project operation; (4) Adequacy of the design effort to provide a sound foundation to support execution of project; (5) Ability of the organization to fully integrate the system, and direct, manage, and control the execution of a complex major project.« less

Space shuttle configuration accounting functional design specification

NASA Technical Reports Server (NTRS)

1974-01-01

An analysis is presented of the requirements for an on-line automated system which must be capable of tracking the status of requirements and engineering changes and of providing accurate and timely records. The functional design specification provides the definition, description, and character length of the required data elements and the interrelationship of data elements to adequately track, display, and report the status of active configuration changes. As changes to the space shuttle program levels II and III configuration are proposed, evaluated, and dispositioned, it is the function of the configuration management office to maintain records regarding changes to the baseline and to track and report the status of those changes. The configuration accounting system will consist of a combination of computers, computer terminals, software, and procedures, all of which are designed to store, retrieve, display, and process information required to track proposed and proved engineering changes to maintain baseline documentation of the space shuttle program levels II and III.

Production of anthocyanins in metabolically engineered microorganisms: Current status and perspectives.

PubMed

Zha, Jian; Koffas, Mattheos A G

2017-12-01

Microbial production of plant-derived natural products by engineered microorganisms has achieved great success thanks to large extend to metabolic engineering and synthetic biology. Anthocyanins, the water-soluble colored pigments found in terrestrial plants that are responsible for the red, blue and purple coloration of many flowers and fruits, are extensively used in food and cosmetics industry; however, their current supply heavily relies on complex extraction from plant-based materials. A promising alternative is their sustainable production in metabolically engineered microbes. Here, we review the recent progress on anthocyanin biosynthesis in engineered bacteria, with a special focus on the systematic engineering modifications such as selection and engineering of biosynthetic enzymes, engineering of transportation, regulation of UDP-glucose supply, as well as process optimization. These promising engineering strategies will facilitate successful microbial production of anthocyanins in industry in the near future.

Safinamide for symptoms of Parkinson's disease.

PubMed

Müller, T

2015-11-01

Chronic and slow progression of neuronal death in Parkinson's disease is responsible for an altered neurotransmission of various biogenic amines, such as dopamine. Therefore, an individually different pronounced heterogeneity of motor and nonmotor symptoms characterizes each Parkinson's disease patient. Ideal candidates for the balance of these neurotransmitter deficits are compounds like safinamide with broad mechanisms of action such as reversible monoamine oxidase type B inhibition, blockage of voltage-dependent sodium channels, modulation of calcium channels and of glutamate release. Safinamide is administered one time daily with oral doses ranging from 50 to 100 mg. Safinamide was well tolerated and safe, ameliorated motor symptoms when combined with dopamine agonist only or additional levodopa in clinical trials. Safinamide is a novel instrument for the drug therapy of Parkinson's disease with better safety and tolerability particularly concerning diarrhea than inhibitors of catechol-O-methyltransferase, like entacapone, according to an indirect comparison within a meta-analysis with entacapone. Copyright 2015 Prous Science, S.A.U. or its licensors. All rights reserved.

An unbalanced portfolio.

PubMed

Federsel, Hans-Jurgen

2009-06-01

An excellent demonstration of how meaningful and valuable conferences devoted to the topic of project and portfolio management in the pharmaceutical industry can be, was given at an event organized in Barcelona, September 2008. Thus, over this 2-day meeting the delegates were updated on the state of the art in this wide-reaching area from speakers representing an array of companies; from small, relatively new players, via mid-sized, to established large and big pharmas. One common theme that emerged was the importance of assessing the value of drug projects as correctly as possible, especially under the current financial climate and the many challenges facing the industry. Furthermore, experiences from constructing portfolios with the aim to minimize risk and maximize return on investment were shared alongside mathematical approaches to obtain the data required for this purpose and accounts of the pleasures and hardships working in a global context and in partnership constellations. Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved.

Inhibition of isolated human myometrium contractility by minoxidil and reversal by glibenclamide.

PubMed

Prabhakaran, S S; Dhanasekar, K R; Thomas, E; Jose, R; Peedicayil, J; Samuel, P

2010-03-01

This study investigated the ability of the antihypertensive drug minoxidil to inhibit potassium chloride (KCl)-induced contractility of the isolated human myometrium. Twelve strips of myometrium obtained from 12 patients who underwent hysterectomy were triggered to contract with 55 mM KCl before and after incubation with 3 concentrations (1, 3 and 10 microM) of minoxidil. The percent inhibition by minoxidil on the extent of contraction, and the area under the contractile curve of KCl-induced contraction of the myometrial strips was determined. Furthermore, the effect of 10 microM glibenclamide on the inhibition generated by 3 microM minoxidil on KCl-induced contractility was studied. It was found that minoxidil produced a concentration-dependent inhibition of KCl-induced contractility of the myometrium and that glibenclamide reversed this inhibitory effect. These results suggest that the inhibitory effect of minoxidil on isolated human myometrium contractility may prove useful in clinical conditions requiring relaxation of the myometrium. 2010 Prous Science, S.A.U. or its licensors. All rights reserved.

Gateways to clinical trials.

PubMed

Tomillero, A; Moral, M A

2009-06-01

(+)-Dapoxetine hydrochloride; Abatacept, Adalimumab, Agalsidase beta, Alemtuzumab, Alglucosidase alfa, Aliskiren fumarate, Ambrisentan, Amlodipine, Aripiprazole, Atrasentan, Azacitidine, Azelnidipine; Belotecan hydrochloride, Bevacizumab, Bilastine, Biphasic insulin aspart, Bortezomib, Bosentan; Caspofungin acetate, CG-100649, Cinacalcet hydrochloride, Clindamycin phosphate/ benzoyl peroxide; Dasatinib, Denosumab, Duloxetine hydrochloride, Dutasteride, Dutasteride/tamsulosin; Ecogramostim, Eculizumab, Eltrombopag olamine, EndoTAG-1, Erlotinib hydrochloride, Everolimus, Exenatide, Ezetimibe; FAHF-2, Fondaparinux sodium; Gefitinib, Golimumab; HEV-239, HSV-TK; Imatinib mesylate, Indium 111 ((111)In) ibritumomab tiuxetan, Influenza vaccine(surface antigen, inactivated, prepared in cell culture), Insulin glargine; Kisspeptin-54; Lidocaine/prilocaine, Lomitapide; Maraviroc, Mirodenafil hydrochloride, MK-8141, MVA-Ag85A; Nilotinib hydrochloride monohydrate; Olmesartan medoxomil; Paclitaxel-eluting stent, Pegfilgrastim, Peginterferon alfa-2a, Peginterferon alfa-2b, Pemetrexed disodium, Pitavastatin calcium, Prasugrel; Recombinant human relaxin H2, RHAMM R3 peptide, Rivaroxaban, Rosuvastatin calcium, RRz2; Sagopilone, Salinosporamide A, SB-509, Serlopitant, Sirolimus-eluting stent, Sorafenib, Sunitinib malate; Tadalafil, Temsirolimus, Teriparatide, TG-4010, Tositumomab/iodine (I131) tositumomab; Velusetrag Hydrochloride; Ximelagatran; Yttrium 90 (90Y) ibritumomab tiuxetan. Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved.

Bilastine for the relief of allergy symptoms.

PubMed

Sádaba Díaz de Rada, B; Azanza Perea, J R; Gomez-Guiu Hormigos, A

2011-04-01

Bilastine is a potent inhibitor of the histamine H1 receptor. It was recently approved in 28 countries of the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria in adults and children older than 12 years. Data from preclinical studies confirmed its selectivity for the histamine H1 receptor over other receptors, and demonstrated antihistaminic and antiallergic properties in vivo. Studies in healthy volunteers and patients have shown that bilastine does not affect driving ability, cardiac conduction or alertness. Bilastine has demonstrated a good safety profile, without serious adverse effects or antimuscarinic effects in clinical trials. There were no significant changes in laboratory tests, electrocardiograms or vital signs. In clinical studies, oral treatment with bilastine 20 mg once daily improved allergic rhinitis with greater efficacy than placebo and comparable to cetirizine and desloratadine. Bilastine 20 mg was more effective than placebo and equivalent to levocetirizine in chronic urticaria, relieving symptoms, improving quality of life and controlling sleep disorders. 2011 Prous Science, S.A.U. or its licensors. All rights reserved.

A report from CPhI Worldwide 2013, Fifth Annual Pre-Connect Conference (October 22-24, 2013 - Frankfurt, Germany).

PubMed

Kuhrt, K; Gilpatrick, J

2013-11-01

A day before the start of the 2013 Conference on Pharmaceutical Ingredients (CPhI) Worldwide, the world's leading pharmaceutical networking event, a number of attendees gathered for the Fifth Annual Pre-Connect Conference to discuss trends in business development, manufacturing and regulatory arenas. Of the six modules presented at the meeting, one was dedicated to the sourcing environment in emerging markets, with special attention paid to developments in India and China. Other modules evaluated the current trends in the creation of generics and supergenerics in emerging markets. Additionally, there were updates on issues surrounding the regulatory and development hurdles that biosimilars and biobetters are facing today. Common themes for both discussions include appropriate pricing and erosion demographics for generics and biosimilars, licensing scenarios, commercialization strategies, and how to stay competitive and find novel innovations within new delivery systems, improved formulations and modifications to create better quality active pharmaceutical ingredients. Copyright 2013 Prous Science, S.A.U. or its licensors. All rights reserved.

Terbinafine: novel formulations that potentiate antifungal activities.

PubMed

Ma, Y; Chen, X; Guan, S

2015-03-01

Terbinafine, an orally and topically active antifungal agent, has been available for the treatment of dermatophytic infections and onychomycosis for more than a decade. In addition, oral administration has been shown to be associated with drug-drug interactions, hepatotoxicity, low concentration at the infected sites, gastrointestinal and systemic side effects and other adverse effects. Since topical drug delivery can provide higher patient compliance, allow immediate access to the infected site and reduce unwanted systemic drug exposure, an improved topical drug delivery approach with high permeability, sustained release and prolonged retainment could overcome the limitations and side effects caused by oral administration. Conventional topical formulations cannot keep the drug in the targeted sites for a long duration of time and hence a novel drug delivery that can avoid the side effects while still providing sustained efficacy in treatment should be developed. This brief review of novel formulations based on polymers and nanostructure carriers provides insight into the efficacy and topical delivery of terbinafine. Copyright 2015 Prous Science, S.A.U. or its licensors. All rights reserved.

Soluble CD30 for the prediction and detection of kidney transplant rejection.

PubMed

Arjona, Alvaro

2009-09-01

Although safer and more effective immunosuppressants as well as enhanced immunosuppressive protocols are continuously being developed in order to increase graft survival, they come at the steep price of drug-related complications and important side effects. In addition, the value of panel reactive antibodies determination, which at present is the single most used indicator of an increased risk of transplant rejection, is now being reevaluated. Therefore, effective tailoring of immunosuppressive therapy minimizing the above-mentioned pitfalls requires the existence of dependable biomarkers that adequately monitor rejection risk both before and after transplantation. Here we review the data yielded by studies assessing the usefulness of measuring soluble CD30 levels (sCD30) in kidney transplant rejection. These data collectively show that sCD30 serum content has a considerable predictive/diagnostic value for acute rejection of renal grafts, particularly when measured a few days after transplantation. Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved.

JAK inhibitors: A broadening approach in rheumatoid arthritis.

PubMed

Lam, S

2016-08-01

Pfizer's Xeljanz (tofacitinib citrate) was the first Janus kinase (JAK) inhibitor to reach the market for rheumatoid arthritis (RA) following its U.S. approval in November 2012, and it has since gained approval in more than 45 countries as a second-line therapy for RA after failure of disease-modifying antirheumatic drugs (DMARDs). This emerging category has heralded an attractive new class of oral treatment options in RA, with a notable opportunity in patients who stop responding to DMARDs, but they are facing a challenging market. Despite RA affecting approximately 23.7 million people worldwide, Xeljanz faces a market dominated by the anti-tumor necrosis factor (anti-TNF) biologicals, which have robust long-term safety and efficacy. The availability of biosimilars of these market leaders is also intensifying competition, and a high price and uncertainty over long-term safety is currently tempering the market for the JAK inhibitors. Copyright 2016 Prous Science, S.A.U. or its licensors. All rights reserved.

Advanced materials research for long-haul aircraft turbine engines

NASA Technical Reports Server (NTRS)

Signorelli, R. A.; Blankenship, C. P.

1978-01-01

The status of research efforts to apply low to intermediate temperature composite materials and advanced high temperature materials to engine components is reviewed. Emerging materials technologies and their potential benefits to aircraft gas turbines were emphasized. The problems were identified, and the general state of the technology for near term use was assessed.

Engineering evaluation of a sodium hydroxide thermal energy storage module

NASA Technical Reports Server (NTRS)

Perdue, D. G.; Gordon, L. H.

1980-01-01

An engineering evaluation of thermal energy storage prototypes was performed in order to assess the development status of latent heat storage media. The testing and the evaluation of a prototype sodium hydroxide module is described. This module stored off-peak electrical energy as heat for later conversion to domestic hot water needs.

14 CFR 121.344 - Digital flight data recorders for transport category airplanes.

Code of Federal Regulations, 2011 CFR

2011-01-01

... as provided in paragraph (l) of this section, no person may operate under this part a turbine-engine... (when an information source is installed); (38) Wind speed and direction (when an information source is... rudder valve status. (b) For all turbine-engine powered transport category airplanes manufactured on or...

14 CFR 121.344 - Digital flight data recorders for transport category airplanes.

Code of Federal Regulations, 2014 CFR

2014-01-01

... as provided in paragraph (l) of this section, no person may operate under this part a turbine-engine... (when an information source is installed); (38) Wind speed and direction (when an information source is... rudder valve status. (b) For all turbine-engine powered transport category airplanes manufactured on or...

14 CFR 121.344 - Digital flight data recorders for transport category airplanes.

Code of Federal Regulations, 2013 CFR

2013-01-01

... as provided in paragraph (l) of this section, no person may operate under this part a turbine-engine... (when an information source is installed); (38) Wind speed and direction (when an information source is... rudder valve status. (b) For all turbine-engine powered transport category airplanes manufactured on or...

14 CFR 121.344 - Digital flight data recorders for transport category airplanes.

Code of Federal Regulations, 2010 CFR

2010-01-01

... as provided in paragraph (l) of this section, no person may operate under this part a turbine-engine... (when an information source is installed); (38) Wind speed and direction (when an information source is... rudder valve status. (b) For all turbine-engine powered transport category airplanes manufactured on or...

14 CFR 121.344 - Digital flight data recorders for transport category airplanes.

Code of Federal Regulations, 2012 CFR

2012-01-01

... as provided in paragraph (l) of this section, no person may operate under this part a turbine-engine... (when an information source is installed); (38) Wind speed and direction (when an information source is... rudder valve status. (b) For all turbine-engine powered transport category airplanes manufactured on or...

77 FR 41363 - BASF Plant Science, LP; Availability of Petition for Determination of Nonregulated Status of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... Genetically Engineered for Herbicide Tolerance AGENCY: Animal and Plant Health Inspection Service, USDA... herbicides in the imidazolinone family. The petition has been submitted in accordance with our regulations... event BPS-CV127-9, which has been genetically engineered for tolerance to herbicides in the...

77 FR 41367 - Dow AgroSciences LLC; Availability of Petition, Plant Pest Risk Assessment, and Environmental...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... Assessment for Determination of Nonregulated Status of Soybean Genetically Engineered for Herbicide Tolerance... been genetically engineered for tolerance to broadleaf herbicides in the phenoxy auxin group (such as the herbicide 2,4-D) and the herbicide glufosinate. The petition has been submitted in accordance with...

77 FR 41361 - Dow AgroSciences LLC; Availability of Petition for Determination of Nonregulated Status of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... Genetically Engineered for Herbicide Tolerance AGENCY: Animal and Plant Health Inspection Service, USDA... broadleaf herbicides in the phenoxy auxin group (such as the herbicide 2,4-D) and the herbicides glyphosate...-44406-6, which has been genetically engineered for tolerance to broadleaf herbicides in the phenoxy...

Space nuclear system thermoelectric NaK pump development

NASA Technical Reports Server (NTRS)

Johnson, J. L.

1973-01-01

The engineering, design, fabrication, and test history of the dual-throat thermoelectric NaK development pump is summarized, along with the engineering and design status of a similar prototype pump intended for use on the 5-kwe reactor thermoelectric system. The history of dc pump development and testing on previous programs is also summarized.

Stirling engines for automobiles

NASA Technical Reports Server (NTRS)

Beremand, D. G.

1979-01-01

The results of recent and ongoing automobile Stirling engine development efforts are reviewed and technology status and requirements are identified. Key technology needs include those for low cost, high temperature (1300 - 1500 F) metal alloys for heater heads, and reliable long-life, low-leakage shaft seals. Various fuel economy projections for Stirling powered automobiles are reviewed and assessed.

Women in Science, Beyond the Research University: Overlooked and Undervalued

ERIC Educational Resources Information Center

Karukstis, Kerry K.

2009-01-01

The underrepresentation of women in almost all science and engineering fields is a well-documented statistic. The National Academies have issued four significant reports since 2001 examining the status and challenges of women in academic science and engineering and offering recommendations to broaden the participation and advancement of women in…

An overview of the Penn State Propulsion Engineering Research Center

NASA Technical Reports Server (NTRS)

Merkle, Charles L.

1991-01-01

An overview of the Penn State Propulsion Engineering Research Center is presented. The following subject areas are covered: research objectives and long term perspective of the Center; current status and operational philosophy; and brief description of Center projects (combustion, fluid mechanics and heat transfer, materials compatibility, turbomachinery, and advanced propulsion concepts).

Real-time neutron imaging of gas turbines

NASA Astrophysics Data System (ADS)

Stewart, P. A. E.

1987-06-01

The current status of real-time neutron radiography imaging is briefly reviewed, and results of tests carried out on cold neutron sources are reported. In particular, attention is given to demonstrations of neutron radiography on a running gas turbine engine. The future role of real-time neutron imaging in engineering diagnostics is briefly discussed.

The Doctorate Production and Baccalaureate Origins of African Americans in the Sciences and Engineering.

ERIC Educational Resources Information Center

Solorzano, Daniel G.

1995-01-01

Reviews the status of black doctorate production from U.S. universities during the 1980s, updating baseline information and examining the baccalaureate origins of African American doctorates. Black students continue to be underrepresented, especially in science and engineering, and gender differences persist. The role of historically black…

The European water framework directive: water quality classification and implications to engineering planning.

PubMed

Achleitner, Stefan; De Toffol, Sara; Engelhard, Carolina; Rauch, Wolfgang

2005-04-01

The European Water framework directive (WFD) is probably the most important environmental management directive that has been enacted over the last decade in the European Union. The directive aims at achieving an overall good ecological status in all European water bodies. In this article, we discuss the implementation steps of the WFD and their implications for environmental engineering practice while focusing on rivers as the main receiving waters. Arising challenges for engineers and scientists are seen in the quantitative assessment of water quality, where standardized systems are needed to estimate the biological status. This is equally of concern in engineering planning, where the prediction of ecological impacts is required. Studies dealing with both classification and prediction of the ecological water quality are reviewed. Further, the combined emission-water quality approach is discussed. Common understanding of this combined approach is to apply the most stringent of either water quality or emission standard to a certain case. In contrast, for example, the Austrian water act enables the application of only the water quality based approach--at least on a temporary basis.

Garrett solar Brayton engine/generator status

NASA Astrophysics Data System (ADS)

Anson, B.

1982-07-01

The solar advanced gas turbine (SAGT-1) is being developed by the Garrett Turbine Engine Company, for use in a Brayton cycle power conversion module. The engine is derived from the advanced gas turbine (AGT101) now being developd by Garrett and Ford Motor Company for automotive use. The SAGT Program is presently funded for the design, fabrication and test of one engine at Garrett's Phoenix facility. The engine when mated with a solar receiver is called a power conversion module (PCU). The PCU is scheduled to be tested on JPL's test bed concentrator under a follow on phase of the program. Approximately 20 kw of electrical power will be generated.

Conventional engine technology. Volume 1: Status of OTTO cycle engine technology

NASA Technical Reports Server (NTRS)

Dowdy, M. W.

1981-01-01

Federally-mandated emissions standards have led to major changes in automotive technology during the last decade. Efforts to satisfy the new standards were directed more toward the use of add-on devices, such as catalytic converters, turbochargers, and improved fuel metering, than toward complete engine redesign. The resulting changes are described and the improvement brought about by them in fuel economy and emissions levels are fully documented. Four specific categories of gasoline-powered internal combustion engines are covered, including subsystem and total engine development. Also included are the results of fuel economy and exhaust emissions tests performed on representative vehicles from each category.

Status, Vision, and Challenges of an Intelligent Distributed Engine Control Architecture

NASA Technical Reports Server (NTRS)

Behbahani, Alireza; Culley, Dennis; Garg, Sanjay; Millar, Richard; Smith, Bert; Wood, Jim; Mahoney, Tim; Quinn, Ronald; Carpenter, Sheldon; Mailander, Bill;

An overview of in-flight plume diagnostics for rocket engines

NASA Technical Reports Server (NTRS)

Madzsar, G. C.; Bickford, R. L.; Duncan, D. B.

1992-01-01

An overview and progress report of the work performed or sponsored by LeRC toward the development of in-flight plume spectroscopy technology for health and performance monitoring of liquid propellant rocket engines are presented. The primary objective of this effort is to develop technology that can be utilized on any flight engine. This technology will be validated by a hardware demonstration of a system capable of being retrofitted onto the Space Shuttle Main Engines for spectroscopic measurements during flight. The philosophy on system definition and status on the development of instrumentation, optics, and signal processing with respect to implementation on a flight engine are discussed.

Are women engineers in Lebanon prepared for the challenges of an engineering profession?

NASA Astrophysics Data System (ADS)

Baytiyeh, Hoda

2013-08-01

This study investigates the status of women engineers in the Middle East, considering women engineers in Lebanon as a case study. The author investigated the following questions: What are the influences behind females' decisions to choose engineering as their major course of study? What are the motives behind this decision? What are the perceptions of females regarding the essential skills for a successful engineering career? An online survey consisting of Likert-scale items was completed by 327 female engineers who graduated from universities in Lebanon and now work in various locations around the world. A genuine interest in the field appeared to be the main influence in the participants' decisions to choose engineering profession. The potential for professional growth was the leading motivator for choosing engineering. Although participants reported that they possessed adequate theoretical knowledge and technical skills before graduation, in the actual practice of engineering, they noted weaknesses in creativity and innovation.

76 FR 27301 - Syngenta Biotechnology, Inc.; Availability of Petition, Plant Pest Risk Assessment, and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-11

... Assessment of Determination of Nonregulated Status for Lepidopteran-Resistant Cotton AGENCY: Animal and Plant... determination of nonregulated status for cotton designated as event COT67B, which has been genetically engineered to express a protein to protect cotton plants from lepidopteran insect damage. The petition has...

78 FR 66891 - Monsanto Co.; Determination of Nonregulated Status of Soybean Genetically Engineered for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

... determination is based on our evaluation of data submitted by the Monsanto Company in its petition for a determination of nonregulated status, our analysis of available scientific data, and comments received from the...' analysis of field and laboratory data submitted by Monsanto, references provided in the petition, peer...

14 CFR Appendix F to Part 91 - Helicopter Flight Recorder Specifications

Code of Federal Regulations, 2010 CFR

2010-01-01

.... Engine Torque Maximum Range ±5% 1 1%2. Flight Control Hydraulic Pressure Primary (Discrete) High/Low 1 Secondary—if applicable (Discrete) High/Low 1 Radio Transmitter Keying (Discrete) On/Off 1 Autopilot Engaged (Discrete) Engaged or Disengaged 1 SAS Status-Engaged (Discrete) Engaged or Disengaged 1 SAS Fault Status...

To deauthorize a portion of the project for navigation, Potomac River, Washington Channel, District of Columbia, under the jurisdiction of the Corps of Engineers.

THOMAS, 111th Congress

Rep. Norton, Eleanor Holmes [D-DC-At Large

2010-06-16

Senate - 07/21/2010 Received in the Senate and Read twice and referred to the Committee on Environment and Public Works. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

The Current Status of Women Professors in China.

ERIC Educational Resources Information Center

Wu, Haiqing

1992-01-01

Presents statistics on the status of female faculty members in China. Reports that in 1987, women comprised just over nine percent of the faculty. Indicates that women are most prevalent in the medical sciences and agronomy but scarcest in engineering and law. Predicts that more women will enter higher education careers. (SG)

Building Links between Early Socioeconomic Status, Cognitive Ability, and Math and Science Achievement

ERIC Educational Resources Information Center

Blums, Angela; Belsky, Jay; Grimm, Kevin; Chen, Zhe

2017-01-01

The present study examined whether and how socioeconomic status (SES) predicts school achievement in science, technology, engineering, and math (STEM) using structural equation modeling and data from the National Institute of Child Health and Human Development Study of Child Care and Youth Development. The present inquiry addresses gaps in…

India Needs International Standards in Accreditation Problems in Adoption and Implementation

ERIC Educational Resources Information Center

Naik, B. M.

2012-01-01

The paper outlines in brief, need and importance of introducing global quality standards in accreditation, prescribed by the international agreement "Washington Accord". This agreement is initially provisional and after scrutiny, if found fit, it is upgraded to Signatory status. It is this status which empowers students of engineering,…

Design of Intelligent Hydraulic Excavator Control System Based on PID Method

NASA Astrophysics Data System (ADS)

Zhang, Jun; Jiao, Shengjie; Liao, Xiaoming; Yin, Penglong; Wang, Yulin; Si, Kuimao; Zhang, Yi; Gu, Hairong

Most of the domestic designed hydraulic excavators adopt the constant power design method and set 85%~90% of engine power as the hydraulic system adoption power, it causes high energy loss due to mismatching of power between the engine and the pump. While the variation of the rotational speed of engine could sense the power shift of the load, it provides a new method to adjust the power matching between engine and pump through engine speed. Based on negative flux hydraulic system, an intelligent hydraulic excavator control system was designed based on rotational speed sensing method to improve energy efficiency. The control system was consisted of engine control module, pump power adjusted module, engine idle module and system fault diagnosis module. Special PLC with CAN bus was used to acquired the sensors and adjusts the pump absorption power according to load variation. Four energy saving control strategies with constant power method were employed to improve the fuel utilization. Three power modes (H, S and L mode) were designed to meet different working status; Auto idle function was employed to save energy through two work status detected pressure switches, 1300rpm was setting as the idle speed according to the engine consumption fuel curve. Transient overload function was designed for deep digging within short time without spending extra fuel. An increasing PID method was employed to realize power matching between engine and pump, the rotational speed's variation was taken as the PID algorithm's input; the current of proportional valve of variable displacement pump was the PID's output. The result indicated that the auto idle could decrease fuel consumption by 33.33% compared to work in maximum speed of H mode, the PID control method could take full use of maximum engine power at each power mode and keep the engine speed at stable range. Application of rotational speed sensing method provides a reliable method to improve the excavator's energy efficiency and realize power match between pump and engine.

University Experiences and Women Engineering Student Persistence

NASA Astrophysics Data System (ADS)

Ayers, LoAnn Debra Gienger

Riverside University (a pseudonym), like many universities, has not significantly increased the number of women who graduate with bachelor's degrees in engineering. The purpose of the study is to understand how the university experiences of women students influence the decision to persist in an undergraduate engineering degree and to understand the role of self-perception in how the students perceive experiences as supporting or hindering their persistence in the major. Archival data, documents and artifacts, observations, individual interviews, and a focus group with women engineering students provide insights into students' perceived barriers and supports of student success. Analysis of the data results in two major themes. First, students' self-confidence and self-efficacy influence how women assimilate university experiences as either supportive or diminishing of academic success. Second, university policies and practices shape the campus environment within which student experiences are formed and influence a student's level of institutional, academic, and social integration. The results of the study indicate opportunities for university leadership to enhance strategies that positively shape students' institutional, academic and social integration as precursors toward increasing the number of women students who successfully complete undergraduate engineering degrees at Riverside University. Future research is indicated to better understand how gender and gender identity intersects with other demographic factors, such as socio-economic status, immigration status, and life stage (e.g., traditional versus non-traditional students), to support or deter the persistence of engineering students to degree completion.

Quality assurance and accreditation of engineering education in Jordan

NASA Astrophysics Data System (ADS)

Aqlan, Faisal; Al-Araidah, Omar; Al-Hawari, Tarek

2010-06-01

This paper provides a study of the quality assurance and accreditation in the Jordanian higher education sector and focuses mainly on engineering education. It presents engineering education, accreditation and quality assurance in Jordan and considers the Jordan University of Science and Technology (JUST) for a case study. The study highlights the efforts undertaken by the faculty of engineering at JUST concerning quality assurance and accreditation. Three engineering departments were accorded substantial equivalency status by the Accreditation Board of Engineering and Technology in 2009. Various measures of quality improvement, including curricula development, laboratories improvement, computer facilities, e-learning, and other supporting services are also discussed. Further assessment of the current situation is made through two surveys, targeting engineering instructors and students. Finally, the paper draws conclusions and proposes recommendations to enhance the quality of engineering education at JUST and other Jordanian educational institutions.

The systems engineering upgrade intiative at NASA's Jet Propulsion Laboratory

NASA Technical Reports Server (NTRS)

Jones, Ross M.

2005-01-01

JPL is implementing an initiative to significantly upgrade our systems engineering capabilities. This Systems Engineering Upgrade Initiative [SUI] has been authorized by the highest level technical management body of JPL and is sponsored with internal funds. The SUI objective is to upgrade system engineering at JPL to a level that is world class, professional and efficient compared to the FY04/05 baseline. JPL system engineering, along with the other engineering disciplines, is intended to support optimum designs; controlled and efficient implementations; and high quality, reliable, cost effective products. SUI technical activities are categorized into those dealing with people, process and tools. The purpose of this paper is to describe the rationale, objectives/plans and current status of the JPL SUI.

Design and development status of ETS-7, an RVD and space robot experiment satellite

NASA Technical Reports Server (NTRS)

Oda, M.; Inagaki, T.; Nishida, M.; Kibe, K.; Yamagata, F.

1994-01-01

ETS-7 (Engineering Test Satellite #7) is an experimental satellite for the in-orbit experiment of the Rendezvous Docking (RVD) and the space robot (RBT) technologies. ETS-7 is a set of two satellites, a chaser satellite and a target satellite. Both satellites will be launched together by NASDA's H-2 rocket into a low earth orbit. Development of ETS-7 started in 1990. Basic design and EM (Engineering Model) development are in progress now in 1994. The satellite will be launched in mid 1997 and the above in-orbit experiments will be conducted for 1.5 years. Design of ETS-7 RBT experiment system and development status are described in this paper.

Welcome to America, welcome to college: Comparing the effects of immigrant generation and college generation on physical science and engineering career

NASA Astrophysics Data System (ADS)

Lung, Florin; Potvin, Geoff; Sonnert, Gerhard; Sadler, Philip M.

2013-01-01

Students enter college with social, cultural, and economic resources (well described Bourdieu's concepts of habitus and capital) that significantly impact their goals, actions, and successes. Two important determinants of the amount and type of resources available to students are their immigrant generation and college generation status. Drawing on a national sample of 6860 freshmen enrolled in college English, we compare and contrast the effects of immigrant generation with those of college generation status on physical science and engineering career intentions to explore some of the challenges faced by the first in the family to become an American and/or go to college.

Project Lead the Ways' Long-Term Effects on Post-Secondary Engineering Academic Success

NASA Astrophysics Data System (ADS)

Zion, George H.

The purpose of this study was to investigate the relationship between students' high school Project Lead They Way participation and their subsequent academic success in post-secondary engineering studies and to assess to what degree, if any, their level of Project Lead The Way (PLTW) participation, gender, and AALANA status (African American, Latino/a American and Native American) effected this success. PLTW is the nation's single largest provider of pre-engineering curriculums, the subject of this research study, currently being offered in over 3,200 secondary schools nationwide. Despite this level of integration, the amount of research on PLTW's effectiveness has been very limited. To date, the majority of the literature on PLTW has examined its impact on students' high school academic performance or their desire to further their engineering studies. The findings from these studies have been overwhelmingly positive, indicating that PLTW students often had greater achievements in math and science and either plan to, or have actually enrolled, in post-secondary studies at higher rates. Nevertheless, the amount of literature on PLTW's effects on students' academic success in post-secondary engineering studies is very limited. Furthermore, no research has yet to examine for the moderating effects of gender, ethnicity, or level of PLTW participation on students' post-secondary academics success. The population of interest for this research study was 1,478 students who entered an undergraduate engineering program from 2007 to 2009 at a privately endowed, co-educational university located in the northeastern United States. The findings of this research study were that virtually all the effects of PLTW participation, gender, and AALANA status had on academic success were observed during students' freshmen and sophomore years. These effects were positive for PLTW participation, and adverse for female and AALANA students. Additionally, PLTW participation, gender, and AALANA status only explained a small amount of the variance for each of the academic success metrics. These conclusions suggest that future research on PLTW should focus on the first and second year of study and expand the factors examined, both quantitative and qualitative, to gain a greater understanding of the complex factors that influence students' initial academic success in post-secondary engineering studies.

Status of the advanced Stirling conversion system project for 25 kW dish Stirling applications

NASA Technical Reports Server (NTRS)

Shaltens, Richard K.; Schreiber, Jeffrey G.

1991-01-01

Heat engines were evaluated for terrestrial Solar Distributed Heat Receivers. The Stirling engine was identified as one of the most promising heat engines for terrestrial applications. Technology development is also conducted for Stirling convertors directed toward a dynamic power source for space applications. Space power requirements include high reliability with very long life, low vibration, and high system efficiency. The free-piston Stirling engine has the potential for future high power space conversion systems, either nuclear or solar powered. Although both applications appear to be quite different, their requirements complement each other.

Avco Lycoming/NASA contract status. [on reduction of emissions from aircraft piston engines

NASA Technical Reports Server (NTRS)

Duke, L. C.

1976-01-01

The standards promulgated by the Environmental Protection Agency (EPA) for carbon monoxide (CO), unburned hydrocarbon (HC), and oxides-of-nitrogen (NOx) emissions were the basis in a study of ways to reduce emissions from aircraft piston engines. A variable valve timing system, ultrasonic fuel atomization, and ignition system changes were postulated.

Reliability, Maintenance and Risk Assessment in Naval Architecture and Marine Engineering Education in the US.

ERIC Educational Resources Information Center

Inozu, Bahadir; Ayyub, Bilal A.

1999-01-01

Examines the current status of existing curricula, accreditation requirements, and new developments in Naval Architecture and Marine Engineering education in the United States. Discusses the emerging needs of the maritime industry in light of advances in information technology and movement toward risk-based, reliability-centered rule making in the…

NASA Lewis Research Center/university graduate research program on engine structures

NASA Technical Reports Server (NTRS)

Chamis, C. C.

1985-01-01

NASA Lewis Research Center established a graduate research program in support of the Engine Structures Research activities. This graduate research program focuses mainly on structural and dynamics analyses, computational mechanics, mechanics of composites and structural optimization. The broad objectives of the program, the specific program, the participating universities and the program status are briefly described.

77 FR 41357 - Monsanto Co.; Availability of Petition for Determination of Nonregulated Status of Canola...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... Produced Through Genetic Engineering Which Are Plant Pests or Which There Is Reason to Believe Are Plant... into the environment) of organisms and products altered or produced through genetic engineering that... CP4 EPSPS expression in male reproductive tissues (i.e., pollen). Enhanced CP4 EPSPS expression in the...

I Didn't Know I Couldn't Do That

NASA Technical Reports Server (NTRS)

Harrison, Dan

2016-01-01

Dan Harrison will discuss overcoming institutional and cultural obstacles that he encountered during his more than 35-year career in engineering and engineering management. He will discuss why it is important to challenge the "unwritten laws" and the status quo that large organizations develop that are contrary to the end-goal of safe, affordable space exploration.

Status of NASA full-scale engine aeroelasticity research

NASA Technical Reports Server (NTRS)

Lubomski, J. F.

1980-01-01

Data relevant to several types of aeroelastic instabilities were obtained using several types of turbojet and turbofan engines. In particular, data relative to separated flow (stall) flutter, choke flutter, and system mode instabilities are presented. The unique characteristics of these instabilities are discussed, and a number of correlations are presented that help identify the nature of the phenomena.

77 FR 42693 - Monsanto Company and KWS SAAT AG; Determination of Nonregulated Status of Sugar Beet Genetically...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-20

... for Tolerance to the Herbicide Glyphosate AGENCY: Animal and Plant Health Inspection Service, USDA... engineered for tolerance to the herbicide glyphosate, designated as H7-1, is no longer considered a regulated... as event H7-1, which has been genetically engineered for tolerance to the herbicide glyphosate. The...

NASA Lewis Research Center/University Graduate Research Program on Engine Structures

NASA Technical Reports Server (NTRS)

Chamis, C. C.

1985-01-01

NASA Lewis Research Center established a graduate research program in support of the Engine Structures Research activities. This graduate research program focuses mainly on structural and dynamics analyses, computational mechanics, mechanics of composites and structural optimization. The broad objectives of the program, the specific program, the participating universities and the program status are briefly described.

Aircraft Piston Engine Exhaust Emission Symposium

NASA Technical Reports Server (NTRS)

1976-01-01

A 2-day symposium on the reduction of exhaust emissions from aircraft piston engines was held on September 14 and 15, 1976, at the Lewis Research Center in Cleveland, Ohio. Papers were presented by both government organizations and the general aviation industry on the status of government contracts, emission measurement problems, data reduction procedures, flight testing, and emission reduction techniques.

14 CFR Appendix E to Part 135 - Helicopter Flight Recorder Specifications

Code of Federal Regulations, 2010 CFR

2010-01-01

... Keying On-Off (Discrete) 1 0.25 sec Power in Each Engine: Free Power Turbine Speed and Engine Torque 0... Hydraulic Pressure Low Discrete, each circuit 1 Flight Control Hydraulic Pressure Selector Switch Position, 1st and 2nd stage Discrete 1 AFCS Mode and Engagement Status Discrete (5 bits necessary) 1 Stability...

76 FR 58272 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-20

... Activities; Submission to OMB for Review and Approval; Comment Request; NESHAP for Engine Test Cells/ Stands... Cells/Stands (Renewal) ICR Numbers: EPA ICR Number 2066.05, OMB Control Number 2060-0483. ICR Status... Hazardous Air Pollutants (NESHAP) for Engine Test Cells/Stands were proposed on May 14, 2002 (67 FR 34547...

Attracting and Retaining Women Students for Science and Engineering. A Report from the Committee on the Status of Women in Ontario Universities.

ERIC Educational Resources Information Center

Council of Ontario Universities, Toronto.

Though women constitute 53% of students graduating annually from provincially assisted Ontario universities with bachelors and first professional degrees, they tend to remain concentrated in fields more conventionally dominated by females, and their representation in traditionally male disciplines (engineering, applied science, mathematics, and…

Graduation and Attrition of Engineering Students in Greece

ERIC Educational Resources Information Center

Caroni, C.

2011-01-01

Greek engineering Schools have a high status and attract good students. However, we show that in the leading institution, the National Technical University of Athens, only 27% of the students admitted in 1992-2003 graduated after the nominal five years study: the median graduation time was 73 months (reaching 93 months in one School) and 12% are…

Mechatronics Engineering Education in India

ERIC Educational Resources Information Center

Bajpai, Shrish; Khare, Sushant

2015-01-01

Present paper aims to give an insight in the field of Mechatronics, specifically its standard of education in India. We have investigated this field right from its origin. We have analyzed how it expanded as a proper discipline of engineering and in which direction the development in this field is going now and, at the same time, its status of…

The Status and Future of Aerospace Engineering Education in Turkey.

ERIC Educational Resources Information Center

Hale, Francis J.

There is no aerospace industry in Turkey, and the level of operational activity is low even though the potential for the exploitation of aviation is high. The government of Turkey hopes to establish an aircraft factory in conjunction with a foreign contractor and is aware of the need for aerospace engineering education. This paper describes the…

Social Identities among Engineering Students and through Their Transition to Work: A Longitudinal Study

ERIC Educational Resources Information Center

Jungert, Tomas

2013-01-01

This article draws on a longitudinal and qualitative study of students in a master's program in engineering. Interpretative phenomenological analysis was used to analyze annual, semi-structured interviews with ten students, from the first semester until one year after graduation. The program enjoys a high status and has a reputation of being…

The Status of Women Faculty in Four-Year Aviation Higher Education Programs

ERIC Educational Resources Information Center

Ison, David C.

2008-01-01

The purpose of the study was to evaluate the status of women's participation in full-time, non-engineering aviation baccalaureate programs in the United States. In addition, the involvement of women in academic aviation leadership positions (such as chair, dean, or director) was evaluated. Of 353 full-time aviation faculty members employed at 60…

Status of fiberoptics technology for propulsion control systems

NASA Technical Reports Server (NTRS)

Baumbick, R. J.

1982-01-01

Optical sensors and optically controlled actuators for use in airbreathing engine control systems are discussed. The environmental conditions in which the aircraft will operate require the fiberoptic cables and optical connectors to perform reliably at temperatures over the -55 C to 260 C range. The status of fiberoptics technology for operation in this environment is reviewed.

76 FR 63279 - Monsanto Co.; Determination of Nonregulated Status for Soybean Genetically Engineered for Insect...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-12

... determination is based on our evaluation of data submitted by the Monsanto Company in its petition for a determination of nonregulated status, our analysis of available scientific data, and comments received from the... Based on APHIS' analysis of field and laboratory data submitted by Monsanto, references provided in the...

A resolution honoring the men and women of the John C. Stennis Space Center on reaching the historic milestone of 50 years of rocket engine testing.

THOMAS, 112th Congress

Sen. Wicker, Roger F. [R-MS

2011-10-20

Senate - 10/21/2011 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

To provide funds to the Army Corps of Engineers to hire veterans and members of the Armed Forces to assist the Corps with curation and historic preservation activities, and for other purposes.

THOMAS, 111th Congress

Rep. Barrow, John [D-GA-12

2010-05-12

Senate - 12/14/2010 Placed on Senate Legislative Calendar under General Orders. Calendar No. 694. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

To provide that funds made available to the Corps of Engineers for certain Missouri River fish and wildlife purposes be used for the reconstruction of flood control structures, and for other purposes.

THOMAS, 112th Congress

Rep. King, Steve [R-IA-5

2011-12-16

House - 01/03/2012 Referred to the Subcommittee on Fisheries, Wildlife, Oceans, and Insular Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Reports of Associated Women Students Commission on the Status of Women, 1969-1970.

ERIC Educational Resources Information Center

Kansas Univ., Lawrence.

This report contains 3 studies made by the Commission on the Status of Women at Kansas University. The first is a survey of the number of female students and faculty members in 7 historically male-dominated schools--Architecture, Business, Engineering, Journalism, Law, Pharmacy, and Social Welfare. The Deans and Assistant Deans of these schools…

Development Status of Higher Education in Northern India: A Review Study

ERIC Educational Resources Information Center

Verma, Chaman

2017-01-01

In development of any country depends upon higher educational status. India is fast growing country in the field of education and technology. Most of IT engineers are deputed in world's most IT companies. It has been possible because of strong development higher education system in India. This paper focuses on the comparative study of higher…

Hydrogen combustion in tomorrow's energy technology

NASA Astrophysics Data System (ADS)

Peschka, W.

The fundamental characteristics of hydrogen combustion and the current status of hydrogen energy applications technology are reviewed, with an emphasis on research being pursued at DFVLR. Topics addressed include reaction mechanisms and pollution, steady-combustion devices (catalytic heaters, H2/air combustors, H2/O2 rocket engines, H2-fueled jet engines, and gas and steam turbine processes), unsteady combustion (in internal-combustion engines with internal or external mixture formation), and feasibility studies of hydrogen-powered automobiles. Diagrams, drawings, graphs, and photographs are provided.

Automotive technology status and projections. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Dowdy, M.; Burke, A.; Schneider, H.; Edmiston, W.; Klose, G. J.; Heft, R.

1978-01-01

Fuel economy, exhaust emissions, multifuel capability, advanced materials and cost/manufacturability for both conventional and advanced alternative power systems were assessed. To insure valid comparisons of vehicles with alternative power systems, the concept of an Otto-Engine-Equivalent (OEE) vehicle was utilized. Each engine type was sized to provide equivalent vehicle performance. Sensitivity to different performance criteria was evaluated. Fuel economy projections are made for each engine type considering both the legislated emission standards and possible future emissions requirements.

Guest Editorial: The Professional Status of European Chemists and Chemical Engineers.

PubMed

Salzer, Reiner; Taylor, Philip; Majcen, Nineta H; De Angelis, Francesco; Wilmet, Sophie; Varella, Evangelia; Kozaris, Ioannis

2015-07-06

Which country pays its chemists and chemical engineers the highest salaries? Where can I find a new job quickest? Which chemical sub-discipline offers most jobs? Reliable answers for these and other questions have been derived from the first European employment survey for chemists and chemical engineers, which was carried out in 2013. Here we publish the first general evaluation of the results of this survey. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

[Innovation guidelines and strategies for pharmaceutical engineering of Chinese medicine and their industrial translation].

PubMed

Cheng, Yi-Yu; Qu, Hai-Bin; Zhang, Bo-Li

2013-01-01

This paper briefly analyzes the bottlenecks and major technical requirements for pharmaceutical industry of Chinese medicine, providing current status of pharmaceutical engineering of Chinese medicine. The innovation directions and strategies of the pharmaceutical engineering for manufacturing Chinese medicine are proposed along with the framework of their core technology. As a consequence, the development of the third-generation pharmaceutical technology for Chinese medicine, featured as "precision, digital and intelligent", is recommended. The prospects of the pharmaceutical technology are also forecasted.

Reusable rocket engine turbopump condition monitoring

NASA Technical Reports Server (NTRS)

Hampson, M. E.; Barkhoudarian, S.

1985-01-01

Significant improvements in engine readiness with attendant reductions in maintenance costs and turnaround times can be achieved with an engine condition monitoring system (CMS). The CMS provides real time health status of critical engine components, without disassembly, through component monitoring with advanced sensor technologies. Three technologies were selected to monitor the rotor bearings and turbine blades: the isotope wear detector and fiber optic deflectometer (bearings), and the fiber optic pyrometer (blades). Signal processing algorithms were evaluated and ranked for their utility in providing useful component health data to unskilled maintenance personnel. Design modifications to current configuration Space Shuttle Main Engine (SSME) high pressure turbopumps and the MK48-F turbopump were developed to incorporate the sensors.

Conventional engine technology. Volume 3: Comparisons and future potential

NASA Technical Reports Server (NTRS)

Dowdy, M. W.

1981-01-01

The status of five conventional automobile engine technologies was assessed and the future potential for increasing fuel economy and reducing exhaust emission was discussed, using the 1980 EPA California emisions standards as a comparative basis. By 1986, the fuel economy of a uniform charge Otto engine with a three-way catalyst is expected to increase 10%, while vehicles with lean burn (fast burn) engines should show a 20% fuel economy increase. Although vehicles with stratified-charge engines and rotary engines are expected to improve, their fuel economy will remain inferior to the other engine types. When adequate NO emissions control methods are implemented to meet the EPA requirements, vehicles with prechamber diesel engines are expected to yield a fuel economy advantage of about 15%. While successful introduction of direct injection diesel engine technology will provide a fuel savings of 30 to 35%, the planned regulation of exhaust particulates could seriously hinder this technology, because it is expected that only the smallest diesel engine vehicles could meet the proposed particulate requirements.

Review of alternate automotive engine fuel economy. Final report January-October 78

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, D.; Bolt, J.A.; Huber, P.

This study assessed the potential of alternate automotive engines to meet the fuel economy goals and emission levels of the 1980-1990 period. As part of NHTSA's continuing research in support of the Department of Transportation fuel economy activities, this study reviewed those developments offering viable substitutes for the current spark ignition engine systems. Categories assessed included stratified charge, diesels, turbo charging, rotary/Wankel engines, and the developmental gas turbine and Stirling cycle engines. Results of past and on-going research through 1978 were reviewed along with the development and production status of various alternate engine technologies proposed for automobiles and light trucksmore » through the 1980s. Assessment was then made of the potential fuel economy improvement as a percentage of 1978 baseline data.« less

Status of the Ford program to evaluate ceramics for stator applications in automotive gas turbine engines

NASA Technical Reports Server (NTRS)

Trela, W.

1980-01-01

The paper reviews the progress of the major technical tasks of the DOE/NASA/Ford program Evaluation of Ceramics for Stator Applications in Automotive Gas Turbine Engines: reliability prediction, stator fabrication, material characterization, and stator evaluation. A fast fracture reliability model was prepared for a one-piece ceramic stator. Periodic inspection results are presented.

Failures and Reform in Mathematics Education: The Case of Engineering. National Institute Briefing Note No. 5.

ERIC Educational Resources Information Center

Wolf, Alison

The structure of education for 16- to 18-year-olds in Great Britain discourages them from making mathematics, science, and engineering serious options for future study. The emerging structure of the labor market, in which a large proportion of high-status jobs do not require higher mathematics, increases the numbers who decide not to commit…

Development of Web-Based Learning Environment Model to Enhance Cognitive Skills for Undergraduate Students in the Field of Electrical Engineering

ERIC Educational Resources Information Center

Lakonpol, Thongmee; Ruangsuwan, Chaiyot; Terdtoon, Pradit

2015-01-01

This research aimed to develop a web-based learning environment model for enhancing cognitive skills of undergraduate students in the field of electrical engineering. The research is divided into 4 phases: 1) investigating the current status and requirements of web-based learning environment models. 2) developing a web-based learning environment…

77 FR 41351 - Bayer CropScience LP; Availability of a Finding of No Significant Impact and a Preliminary...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... an Extension of a Determination of Nonregulated Status of Cotton Genetically Engineered for Herbicide... to extend to cotton event T303-3, which has been genetically engineered to be tolerant to the... of TwinLink TM cotton (event T304-40). We are making available for public comment our finding of no...

Certification of a weld produced by friction stir welding

DOEpatents

Obaditch, Chris; Grant, Glenn J

2013-10-01

Methods, devices, and systems for providing certification of friction stir welds are disclosed. A sensor is used to collect information related to a friction stir weld. Data from the sensor is compared to threshold values provided by an extrinsic standard setting organizations using a certification engine. The certification engine subsequently produces a report on the certification status of the weld.

NSF announces diversity programme

NASA Astrophysics Data System (ADS)

Kruesi, Liz

2016-04-01

The US National Science Foundation (NSF) has initiated a new funding programme that will create schemes to increase diversity in science, technology, engineering and mathematics (STEM). The initiative - Inclusion across the Nation of Communities of Learners of Underrepresented Discoverers in Engineering and Science (INCLUDES) - aims to increase the participation of women, those with a low socioeconomic status, people with disabilities and those from minority racial backgrounds.

Peroxide Propulsion at the Turn of the Century

NASA Technical Reports Server (NTRS)

Anderson, William E.; Butler, Kathy; Crocket, Dave; Lewis, Tim; McNeal, Curtis

2000-01-01

A resurgence of interest in peroxide propulsion has occurred in the last years of the 21st Century. This interest is driven by the need for lower cost propulsion systems and the need for storable reusable propulsion systems to meet future space transportation system architectures. NASA and the Air Force are jointly developing two propulsion systems for flight demonstration early in the 21st Century. One system will be a development of Boeing's AR2-3 engine, which was successfully fielded in the 1960s. The other is a new pressure-fed design by Orbital Sciences Corporation for expendable mission requirements. Concurrently NASA and industry are pursuing the key peroxide technologies needed to design, fabricate, and test advanced peroxide engines to meet the mission needs beyond 2005. This paper will present a description of the AR2-3, report the status of its current test program, and describe its intended flight demonstration. This paper will then describe the Orbital 10K engine, the status of its test program, and describe its planned flight demonstration. Finally the paper will present a plan, or technology roadmap, for the development of an advanced peroxide engine for the 21st Century.

Geomagnetically induced currents: Science, engineering, and applications readiness

NASA Astrophysics Data System (ADS)

Pulkkinen, A.; Bernabeu, E.; Thomson, A.; Viljanen, A.; Pirjola, R.; Boteler, D.; Eichner, J.; Cilliers, P. J.; Welling, D.; Savani, N. P.; Weigel, R. S.; Love, J. J.; Balch, C.; Ngwira, C. M.; Crowley, G.; Schultz, A.; Kataoka, R.; Anderson, B.; Fugate, D.; Simpson, J. J.; MacAlester, M.

2017-07-01

This paper is the primary deliverable of the very first NASA Living With a Star Institute Working Group, Geomagnetically Induced Currents (GIC) Working Group. The paper provides a broad overview of the current status and future challenges pertaining to the science, engineering, and applications of the GIC problem. Science is understood here as the basic space and Earth sciences research that allows improved understanding and physics-based modeling of the physical processes behind GIC. Engineering, in turn, is understood here as the "impact" aspect of GIC. Applications are understood as the models, tools, and activities that can provide actionable information to entities such as power systems operators for mitigating the effects of GIC and government agencies for managing any potential consequences from GIC impact to critical infrastructure. Applications can be considered the ultimate goal of our GIC work. In assessing the status of the field, we quantify the readiness of various applications in the mitigation context. We use the Applications Readiness Level (ARL) concept to carry out the quantification.

Geomagnetically induced currents: Science, engineering, and applications readiness

USGS Publications Warehouse

Pulkkinen, Antti; Bernabeu, E.; Thomson, A.; Viljanen, A.; Pirjola, R.; Boteler, D.; Eichner, J.; Cilliers, P.J.; Welling, D.; Savani, N.P.; Weigel, R.S.; Love, Jeffrey J.; Balch, Christopher; Ngwira, C.M.; Crowley, G.; Schultz, Adam; Kataoka, R.; Anderson, B.; Fugate, D.; Simpson, J.J.; MacAlester, M.

2017-01-01

This paper is the primary deliverable of the very first NASA Living With a Star Institute Working Group, Geomagnetically Induced Currents (GIC) Working Group. The paper provides a broad overview of the current status and future challenges pertaining to the science, engineering, and applications of the GIC problem. Science is understood here as the basic space and Earth sciences research that allows improved understanding and physics-based modeling of the physical processes behind GIC. Engineering, in turn, is understood here as the “impact” aspect of GIC. Applications are understood as the models, tools, and activities that can provide actionable information to entities such as power systems operators for mitigating the effects of GIC and government agencies for managing any potential consequences from GIC impact to critical infrastructure. Applications can be considered the ultimate goal of our GIC work. In assessing the status of the field, we quantify the readiness of various applications in the mitigation context. We use the Applications Readiness Level (ARL) concept to carry out the quantification.

KSC technicians on team to modify X-34

NASA Technical Reports Server (NTRS)

1999-01-01

The modified X-34, known as A-1A, rests in the background of the Dryden Flight Research Center at Edwards Air Force Base, Calif., while an integrated team of KSC, Dryden Flight Research Center and Orbital Sciences Corporation engineers and technicians bring the X-34 A-1A vehicle closer to test flight readiness. Since September, eight NASA engineering technicians from KSC's Engineering Prototype Lab have assisted in the complex process of converting the X-34 A-1 vehicle from captive carry status to unpowered flight status, the A-1A. The X-34 is 58.3 feet long, 27.7 feet wide from wing tip to wing tip, and 11.5 feet tall from the bottom of the fuselage to the top of the tail. The autonomously operated technology demonstrator will be air- launched from an L-1011 airplane and should be capable of flying eight times the speed of sound, reaching an altitude of 250,000 feet. The X-34 Project is managed by NASA's Marshall Space Flight Center in Huntsville, Ala.

A resolution expressing support for a public diplomacy program promoting advancements in science, technology, engineering, and mathematics made by or in partnership with the people of the United States.

THOMAS, 111th Congress

Sen. Kaufman, Edward E. [D-DE

2010-09-28

Senate - 09/28/2010 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

Telecommunications Research in the United States and Selected Foreign Countries: A Preliminary Survey. Volume II, Individual Contributions.

ERIC Educational Resources Information Center

National Academy of Engineering, Washington, DC. Committee on Telecommunications.

At the request of the National Science Foundation, the Panel on Telecommunications Research of the Committee on Telecommunications of the National Academy of Engineering has made a preliminary survey of the status and trends of telecommunications research in the United States and selected foreign countries. The status and trends were identified by…

Strain sensing technology for high temperature applications

NASA Technical Reports Server (NTRS)

Williams, W. Dan

1993-01-01

This review discusses the status of strain sensing technology for high temperature applications. Technologies covered are those supported by NASA such as required for applications in hypersonic vehicles and engines, advanced subsonic engines, as well as material and structure development. The applications may be at temperatures of 540 C (1000 F) to temperatures in excess of 1400 C (2500 F). The most promising technologies at present are the resistance strain gage and remote sensing schemes. Resistance strain gages discussed include the BCL gage, the LaRC compensated gage, and the PdCr gage. Remote sensing schemes such as laser based speckle strain measurement, phase-shifling interferometry, and x-ray extensometry are discussed. Present status and limitations of these technologies are presented.

NEP systems engineering efforts in FY-92: Plans and status

NASA Technical Reports Server (NTRS)

Doherty, Michael P.; Gilland, James H.

1992-01-01

A system engineering effort has been initiated by NASA in FY-92 to define, address, and resolve issues associated with the use of Nuclear Electric Propulsion (NEP) for megawatt (MW) space propulsion applications associated with the Space Exploration Initiative (SEI). It is intended that key technical issues will be addressed by activities conducted in the early years of a project in NEP, with the objective of resolving such issues. Also, in response to more recent programmatic direction, a concept definition activity for 100 kilowatt NEP is being initiated. This paper will present key issues associated with megawatt NEP, and the plans and status for their resolution, and present the scope and rationale for the 100 kilowatt concept definition activity.

The development of biomedical engineering as experienced by one biomedical engineer

PubMed Central

2012-01-01

This personal essay described the development of the field of Biomedical Engineering from its early days, from the perspective of one who lived through that development. It describes the making of a major invention using data that had been rejected by other scientists, the re-discovery of an obscure fact of physiology and its use in developing a major medical instrument, the development of a new medical imaging modality, and the near-death rescue of a research project. The essay concludes with comments about the development and present status of impedance imaging, and recent changes in the evolution of biomedical engineering as a field. PMID:23234267

Status of an inlet configuration trade study for the Douglas HSCT

NASA Technical Reports Server (NTRS)

Jones, Jay R.; Welge, H. Robert

1992-01-01

An inlet concept integration trade study for an HSCT is being conducted under contract to NASA LeRC. The HSCT mission has a supersonic cruise Mach number of 2.4 and a subsonic cruise Mach number of 0.95. The engine selected for this study is the GE VCE (variable cycle engine) with FLADE (fan on blade). Six inlet configurations will be defined. Inlet configurations will be axisymmetric and rectangular mixed-compression inlets in single-engine nacelles. Airplane performance for each inlet configuration will be estimated and then compared. The most appropriate inlet configuration for this airplane/engine combination will be determined by Sep. 1991.

The development of biomedical engineering as experienced by one biomedical engineer.

PubMed

Newell, Jonathan C

2012-12-12

This personal essay described the development of the field of Biomedical Engineering from its early days, from the perspective of one who lived through that development. It describes the making of a major invention using data that had been rejected by other scientists, the re-discovery of an obscure fact of physiology and its use in developing a major medical instrument, the development of a new medical imaging modality, and the near-death rescue of a research project. The essay concludes with comments about the development and present status of impedance imaging, and recent changes in the evolution of biomedical engineering as a field.

A computer simulator for development of engineering system design methodologies

NASA Technical Reports Server (NTRS)

Padula, S. L.; Sobieszczanski-Sobieski, J.

1987-01-01

A computer program designed to simulate and improve engineering system design methodology is described. The simulator mimics the qualitative behavior and data couplings occurring among the subsystems of a complex engineering system. It eliminates the engineering analyses in the subsystems by replacing them with judiciously chosen analytical functions. With the cost of analysis eliminated, the simulator is used for experimentation with a large variety of candidate algorithms for multilevel design optimization to choose the best ones for the actual application. Thus, the simulator serves as a development tool for multilevel design optimization strategy. The simulator concept, implementation, and status are described and illustrated with examples.

Engineering microbial electrocatalysis for chemical and fuel production.

PubMed

Rosenbaum, Miriam A; Henrich, Alexander W

2014-10-01

In many biotechnological areas, metabolic engineering and synthetic biology have become core technologies for biocatalyst development. Microbial electrocatalysis for biochemical and fuel production is still in its infancy and reactions rates and the product spectrum are currently very low. Therefore, molecular engineering strategies will be crucial for the advancement and realization of many new bioproduction routes using electroactive microorganisms. The complex and unresolved biochemistry and physiology of extracellular electron transfer and the lack of molecular tools for these new non-model hosts for genetic engineering constitute the major challenges for this effort. This review is providing an insight into the current status, challenges and promising approaches of pathway engineering for microbial electrocatalysis. Copyright © 2014 Elsevier Ltd. All rights reserved.

Integrating ethics in design through the value-sensitive design approach.

PubMed

Cummings, Mary L

2006-10-01

The Accreditation Board of Engineering and Technology (ABET) has declared that to achieve accredited status, 'engineering programs must demonstrate that their graduates have an understanding of professional and ethical responsibility.' Many engineering professors struggle to integrate this required ethics instruction in technical classes and projects because of the lack of a formalized ethics-in-design approach. However, one methodology developed in human-computer interaction research, the Value-Sensitive Design approach, can serve as an engineering education tool which bridges the gap between design and ethics for many engineering disciplines. The three major components of Value-Sensitive Design, conceptual, technical, and empirical, exemplified through a case study which focuses on the development of a command and control supervisory interface for a military cruise missile.

Shortage of Engineers and Scientists. Hearing before the Subcommittee on Science, Technology, and Space of the Committee on Commerce, Science, and Transportation. United States Senate One Hundred First Congress, Second Session on Training Scientists and Engineers for the Year 2000--The National Science Foundation's Role.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. Senate Committee on Commerce, Science, and Transportation.

This document is the transcript of a Congressional hearing focusing on the status of the training of scientists and engineers in the United States and the role of the federal government in the improvement of this situation. Included are opening statements from Senators Albert Gore, Jr. (Tennessee), Robert W. Kasten, Jr. (Wisconsin), and Larry…

Free piston space Stirling technology program

NASA Technical Reports Server (NTRS)

Dochat, G. R.; Dhar, M.

1989-01-01

MTI recently completed an initial technology feasibility program for NASA by designing, fabricating and testing a space power demonstrator engine (SPDE). This program, which confirms the potential of free-piston Stirling engines, provided the major impetus to initiate a free-piston Stirling space engine (SSE) technology program. The accomplishments of the SPDE program are reviewed, and an overview of the SSE technology program and technical status to date is provided. It is shown that progress in both programs continues to justify its potential for either nuclear or solar space power missions.

Ceramic thermal barrier coatings for commercial gas turbine engines

NASA Technical Reports Server (NTRS)

Meier, Susan Manning; Gupta, Dinesh K.; Sheffler, Keith D.

1991-01-01

The paper provides an overview of the short history, current status, and future prospects of ceramic thermal barrier coatings for gas turbine engines. Particular attention is given to plasma-sprayed and electron beam-physical vapor deposited yttria-stabilized (7 wt pct Y2O3) zirconia systems. Recent advances include improvements in the spallation life of thermal barrier coatings, improved bond coat composition and spraying techniques, and improved component design. The discussion also covers field experience, life prediction modeling, and future directions in ceramic coatings in relation to gas turbine engine design.

Why They Leave: The Impact of Stereotype Threat on the Attrition of Women and Minorities from Science, Math and Engineering Majors

ERIC Educational Resources Information Center

Beasley, Maya A.; Fischer, Mary J.

2012-01-01

This paper examines the effects of group performance anxiety on the attrition of women and minorities from science, math, and engineering majors. While past research has relied primarily on the academic deficits and lower socioeconomic status of women and minorities to explain their absence from these fields, we focus on the impact of stereotype…

An Appraisal of an Online Tutorial System for the Teaching and Learning of Engineering Physics in Conjunction with Contextual Physics and Mathematics, and Relevant Mathematics

ERIC Educational Resources Information Center

Bhathal, Ragbir

2016-01-01

The number of students entering engineering schools in Australian universities has increased tremendously over the last few years because of the Australian Federal Government's policy of increasing the participation rates of Higher School Certificate students and students from low social economic status backgrounds in the tertiary sector. They now…

Supporting the goals and ideals of National Engineers Week.

THOMAS, 113th Congress

Rep. Lipinski, Daniel [D-IL-3

2014-02-11

House - 02/11/2014 Referred to the Committee on Science, Space, and Technology, and in addition to the Committee on Education and the Workforce, for a period to be subsequently determined by the Speaker, in each case for consideration of such provisions as fall within the... (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

A resolution expressing support for the goals and ideals of the biennial USA Science & Engineering Festival in Washington, DC and designating April 21 through April 27, 2014, as "National Science and Technology Week".

THOMAS, 113th Congress

Sen. Coons, Christopher A. [D-DE

2014-01-07

Senate - 01/07/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

The Study of Technology as a Field of Knowledge in General Education: Historical Insights and Methodological Considerations from a Swedish Case Study, 1842-2010

ERIC Educational Resources Information Center

Hallström, Jonas; Hultén, Magnus; Lövheim, Daniel

2014-01-01

Today, technology education in Sweden is both a high-status and a low-status phenomenon. Positive values such as economic growth, global competitiveness and the sustainability of the welfare state are often coupled with higher engineering education and sometimes even upper secondary education. Negative values, on the other hand, are often…

A resolution commending the participants in the 44th International Chemistry Olympiad and recognizing the importance of education in the fields of science, technology, engineering, and mathematics to the future of the United States.

THOMAS, 112th Congress

Sen. Coons, Christopher A. [D-DE

2012-06-12

Senate - 06/12/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

Supporting the goals and ideals of National Engineers Week.

THOMAS, 113th Congress

Rep. Lipinski, Daniel [D-IL-3

2013-02-25

House - 02/25/2013 Referred to the Committee on Science, Space, and Technology, and in addition to the Committee on Education and the Workforce, for a period to be subsequently determined by the Speaker, in each case for consideration of such provisions as fall within the... (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

The Current Status of Modular Coordination. A Research Correlation Conference of Building Research Institute, Division of Engineering and Industrial Research (Fall 1959).

ERIC Educational Resources Information Center

National Academy of Sciences - National Research Council, Washington, DC.

Publication of conference presentations include--(1) a brief review of current modular standard development, (2) the statistical status of modular practice, (3) availability of modular products, and (4) educational programs on modular coordination. Included are--(1) explanatory diagrams, (2) text of an open panel discussion, and (3) a list of…

Specialized data analysis for the Space Shuttle Main Engine and diagnostic evaluation of advanced propulsion system components

NASA Technical Reports Server (NTRS)

1993-01-01

The Marshall Space Flight Center is responsible for the development and management of advanced launch vehicle propulsion systems, including the Space Shuttle Main Engine (SSME), which is presently operational, and the Space Transportation Main Engine (STME) under development. The SSME's provide high performance within stringent constraints on size, weight, and reliability. Based on operational experience, continuous design improvement is in progress to enhance system durability and reliability. Specialized data analysis and interpretation is required in support of SSME and advanced propulsion system diagnostic evaluations. Comprehensive evaluation of the dynamic measurements obtained from test and flight operations is necessary to provide timely assessment of the vibrational characteristics indicating the operational status of turbomachinery and other critical engine components. Efficient performance of this effort is critical due to the significant impact of dynamic evaluation results on ground test and launch schedules, and requires direct familiarity with SSME and derivative systems, test data acquisition, and diagnostic software. Detailed analysis and evaluation of dynamic measurements obtained during SSME and advanced system ground test and flight operations was performed including analytical/statistical assessment of component dynamic behavior, and the development and implementation of analytical/statistical models to efficiently define nominal component dynamic characteristics, detect anomalous behavior, and assess machinery operational condition. In addition, the SSME and J-2 data will be applied to develop vibroacoustic environments for advanced propulsion system components, as required. This study will provide timely assessment of engine component operational status, identify probable causes of malfunction, and indicate feasible engineering solutions. This contract will be performed through accomplishment of negotiated task orders.

IECEC '84: Advanced energy systems - Their role in our future; Proceedings of the Nineteenth Intersociety Energy Conversion Engineering Conference, San Francisco, CA, August 19-24, 1984. Volumes 1, 2, 3, & 4

NASA Astrophysics Data System (ADS)

Among the topics discussed are: advanced energy conversion concepts, power sources for aircraft and spacecraft, alternate fuels for industrial and vehicular applications, biomass-derived fuels, electric vehicle design and development status, electrochemical energy conversion systems, electric power generation cycles, energy-efficient industrial processes, and energy policy and system analysis. Also discussed are advanced methods for energy storage and transport, fossil fuel conversion systems, geothermal energy system development and performance, novel and advanced heat engines, hydrogen fuel-based energy systems, MHD technology development status, nuclear energy systems, solar energy conversion methods, advanced heating and cooling systems, Stirling cycle device development, terrestrial photovoltaic systems, and thermoelectric and thermionic systems.

Recent Cooperative Research Activities of HDD and Flexible Media Transport Technologies in Japan

NASA Astrophysics Data System (ADS)

Ono, Kyosuke

This paper presents the recent status of industry-university cooperative research activities in Japan on the mechatronics of information storage and input/output equipment. There are three research committees for promoting information exchange on technical problems and research topics of head-disk interface in hard disk drives (HDD), flexible media transport and image printing processes which are supported by the Japan Society of Mechanical Engineering (JSME), the Japanese Society of Tribologists (JAST) and the Japan Society of Precision Engineering (JSPE). For hard disk drive technology, the Storage Research Consortium (SRC) is supporting more than 40 research groups in various different universities to perform basic research for future HDD technology. The past and present statuses of these activities are introduced, particularly focusing on HDD and flexible media transport mechanisms.

Development of an integrated indicator system to assess the impacts of reclamation engineering on a river estuary.

PubMed

Xu, Yan; Cai, Yanpeng; Sun, Tao; Yin, Xin'An; Tan, Qian

2017-06-30

An integrated indicator system was developed for determining synthetic environmental responses under multiple types of coastal reclamation engineering in the Yellow River estuary, China. Four types of coastal engineering works were analyzed, namely port construction, petroleum exploitation, fishery and aquaculture, and seawall defense. In addition, two areas with limited human disturbances were considered for comparison. From the weights of the response value for each indicator, port construction was determined to be the primary impact contributor among the four engineering works studies. Specifically, hydrodynamic conditions, ecological status, economic costs, and engineering intensity were on average 72.78%, 65.03%, 75.03%, and 66.35% higher than those of other engineering types. Furthermore, fishery and aquaculture impact on water quality was 42.51% higher than that of other engineering types, whereas seawall defense impact on landscape variation was 51.75% higher than that of other engineering types. The proposed indicator system may provide effective coastal management in future. Copyright © 2017 Elsevier Ltd. All rights reserved.

Evaluation of ceramics for stator application: Gas turbine engine report

NASA Technical Reports Server (NTRS)

Trela, W.; Havstad, P. H.

1978-01-01

Current ceramic materials, component fabrication processes, and reliability prediction capability for ceramic stators in an automotive gas turbine engine environment are assessed. Simulated engine duty cycle testing of stators conducted at temperatures up to 1093 C is discussed. Materials evaluated are SiC and Si3N4 fabricated from two near-net-shape processes: slip casting and injection molding. Stators for durability cycle evaluation and test specimens for material property characterization, and reliability prediction model prepared to predict stator performance in the simulated engine environment are considered. The status and description of the work performed for the reliability prediction modeling, stator fabrication, material property characterization, and ceramic stator evaluation efforts are reported.

Osimertinib, a third-generation tyrosine kinase inhibitor targeting non-small cell lung cancer with EGFR T790M mutations.

PubMed

McCoach, C E; Jimeno, A

2016-10-01

Oncogenic driver mutations in the epidermal growth factor receptor (EGFR) gene have provided a focus for effective targeted therapy. Unfortunately, all patients eventually develop resistance to frontline therapy with EGFR tyrosine kinase inhibitors (TKIs). The majority of patients develop a large subclonal population of tumor cells with a T790M mutation that renders these cells resistant to first-generation TKIs. Osimertinib is a third-generation EGFR TKI that was designed to overcome resistance from T790M mutations. This agent has demonstrated strong preclinical activity, and in the clinic it has demonstrated a high objective response rate and progression-free survival in patients with EGFR double mutations (L858R/T790M and exon 19 deletion/T790M). It is now approved by the FDA for patients who have a documented T790M mutation and who have progressed on a prior TKI. Osimertinib is also approved in the E.U. and Japan. Copyright 2016 Prous Science, S.A.U. or its licensors. All rights reserved.

Subcutaneous insulin therapy - end of the road after 80 years?

PubMed

Leifke, E; Strack, T R

2014-02-01

Subcutaneous (SC) insulin therapy has been a mainstay of pharmacological diabetes management from the moment insulin was successfully developed as treatment. Insulin formulations have become more refined and less allergenic over time, and ancillary technologies such as injection devices and glucose measurement tools have evolved to the extent of permitting closed-loop therapy. However, investigations have continued exploring alternative routes of administration with the ultimate goal of implantable islet replacements, whether cell- or "silicon"-based. Progress on these lines of research, however, has been slow to present patients with viable options: alternative delivery routes have failed to deliver insulin reliably and with commercially viable efficiency, while beta cell transplantation continues to struggle with tissue availability and in vivo viability. In the meantime, SC insulin formulations have advanced for rapid- and long-acting formulations, to better meet typical insulin requirements across the day. Thus, SC insulin will likely remain a key technology for the foreseeable future in order to address the needs of an ever larger number of insulin-dependent patients with diabetes. Copyright 2014 Prous Science, S.A.U. or its licensors. All rights reserved.

A review of preserved and preservative-free prostaglandin analogues for the treatment of open-angle glaucoma and ocular hypertension.

PubMed

Hommer, A

2010-06-01

Glaucoma affects an increasing number of people worldwide and is the second leading cause of blindness. The aim of antiglaucoma therapy is to maintain a patient's visual function and quality of life. Prostaglandin analogues are first-line topical antiglaucoma therapy. They are effective at lowering intraocular pressure (IOP) and are generally well tolerated, with fewer systemic adverse events compared with the other classes. However, the use of prostaglandin analogues can be associated with ocular adverse effects, such as stinging/burning sensation, dry eyes, iris and periocular hyperpigmentation, and eye lash growth, which can affect patient compliance. Preservatives used in antiglaucoma preparations can have dose-dependent toxic effects, which contribute to adverse effects. The development of preservative-free preparations may reduce such adverse effects and therefore improve patient compliance. Tafluprost is a prostaglandin analogue in a preservative-free formulation that was recently approved for the reduction of elevated IOP in open-angle glaucoma and ocular hypertension. Copyright 2010 Prous Science, S.A.U. or its licensors. All rights reserved.

Canakinumab for the treatment of cryopyrin-associated periodic syndromes.

PubMed

Walsh, Garry M

2009-10-01

Familial cold-induced autoinflammatory syndrome, Muckle-Wells syndrome and neonatal-onset multisystem inflammatory disease make up cryopyrin-associated periodic syndromes (CAPS). These are autoinflammatory inherited disorders caused by autosomal dominant gain-of-function mutations in the NLRP3 gene, located on chromosome 1q44. Cryopyrin/NALP3/NLRP3 is an essential component of intracellular inflammasomes that activate caspase-1, which in turn converts interleukin-1beta (IL-1beta) to its active form. IL-1beta is a potent cytokine that activates diverse elements of the immune and inflammatory systems leading to the pathogenic changes characteristic of CAPS. There is therefore much interest in the development of IL-1beta blocking agents as novel biologic treatments for these conditions. Canakinumab (ACZ-885; Ilaris, Novartis Pharma) is a fully humanized monoclonal antibody (mAb) specific for IL-1beta and is indicated for a wide range of inflammatory disorders including CAPS. This review will assess the utility of canakinumab as a treatment for CAPS. Copyright 2009 Prous Science, S.A.U. or its licensors. All rights reserved.

Inhaled antibiotics for lower respiratory tract infections: focus on ciprofloxacin.

PubMed

Serisier, D J

2012-05-01

The administration of antibiotics by the inhaled route offers an appealing and logical approach to treating infectious respiratory conditions. Studies in the cystic fibrosis (CF) population have established the efficacy of this therapeutic concept and inhaled antibiotic therapy is now one of the pillars of management in CF. There are now a number of new inhaled antibiotic formulations that have shown impressive preliminary evidence for efficacy in CF and are commencing phase III efficacy studies. Translation of this paradigm into the non-CF bronchiectasis population has proven difficult thus far, apparently due to problems with tolerability of inhaled formulations. Inhaled versions of ciprofloxacin have shown good tolerability and microbiological efficacy in preliminary studies, suggesting that effective inhaled antibiotics are finally on the horizon for this previously neglected patient population. The increased use of long-term inhaled antibiotics for a wider range of non-CF indications presents risks to the broader community of greater antimicrobial resistance development that must be carefully weighed against any demonstrated benefits. Copyright 2012 Prous Science, S.A.U. or its licensors. All rights reserved.

Quantitative proteomic analysis in breast cancer.

PubMed

Tabchy, A; Hennessy, B T; Gonzalez-Angulo, A M; Bernstam, F M; Lu, Y; Mills, G B

2011-02-01

Much progress has recently been made in the genomic and transcriptional characterization of tumors. However, historically the characterization of cells at the protein level has suffered limitations in reproducibility, scalability and robustness. Recent technological advances have made it possible to accurately and reproducibly portray the global levels and active states of cellular proteins. Protein microarrays examine the native post-translational conformations of proteins including activated phosphorylated states, in a comprehensive high-throughput mode, and can map activated pathways and networks of proteins inside the cells. The reverse-phase protein microarray (RPPA) offers a unique opportunity to study signal transduction networks in small biological samples such as human biopsy material and can provide critical information for therapeutic decision-making and the monitoring of patients for targeted molecular medicine. By providing the key missing link to the story generated from genomic and gene expression characterization efforts, functional proteomics offer the promise of a comprehensive understanding of cancer. Several initial successes in breast cancer are showing that such information is clinically relevant. Copyright 2011 Prous Science, S.A.U. or its licensors. All rights reserved.

A report from the European Society of Cardiology Congress 2013 (August 31-September 4, 2013 - Amsterdam, the Netherlands).

PubMed

Rabasseda, X

2013-09-01

Many are the diseases that can affect the heart and the vessels, most of which were discussed during the European Society of Cardiology Congress 2013 in Amsterdam. With an attendance of almost 30,000 delegates buzzing the halls of the RAI convention center, Amsterdam was the capital of cardiologic science this summer, and a big challenge for any attendee trying to get the most out of all the oral and poster sessions missing the minimum of new science being presented. Thomson Reuters Cortellis™ supplements the information for any scientist who missed an important session, with a particular focus on new investigational drugs, many of them still in preclinical research, which will certainly impact how cardiovascular disorders are treated in a foreseeable future. Clinical and preclinical research advance to bring novel therapeutic targets, new drugs and new insight into patient characteristics requiring particular treatment approaches. This report is a sample of the new science discussed during the 5 days of meetings. Copyright 2013 Prous Science, S.A.U. or its licensors. All rights reserved.

A report from the European Association for the Study of the Liver's 50th International Liver Congress (April 22-26 - Vienna, Austria).

PubMed

Rabasseda, X

2015-04-01

While Vienna's Prater park offers a varied selection of options, from theme parks to lush gardens and prairies to enjoy the sun, the nearby Messe Wien convention center was the focus of attention in April 2015 for all the scientists, researchers and clinicians interested in viral hepatitis, nonalcoholic steatohepatitis, hepatocellular carcinoma and a variety of other liver diseases. Treatments and potential new therapeutic strategies for these hepatopathies were discussed during the 50th International Liver Congress organized by the European Association for the Study of the Liver. Echoing epidemiological facts and a high social interest for hepatitis C virus infection, new findings with investigational and potential new therapies for the disease centered much of the attention at the conference. Nevertheless, new research was also reported related to potential improvements in how other liver diseases, particularly hepatitis B virus infection, hepatocellular carcinoma and a range of inflammatory and immune-mediated liver diseases, including rare hereditary diseases that should never be forgotten. Copyright 2015 Prous Science, S.A.U. or its licensors. All rights reserved.

Overview of the 1985 NASA Lewis Research Center SP-100 free-piston Stirling engine activities

NASA Technical Reports Server (NTRS)

Slaby, J.

1985-01-01

This effort is keyed on the design, fabrication, assembly, and testing of a 25 kWe Stirling space-power technology-feasibility demonstrator engine. Another facet of the SP-100 project covers the status of a 9000-hr endurance test conducted on a 2 kWe free-piston Stirling/linear alternator system employing hydrostatic gas bearings. Dynamic balancing of the RE-1000 engine (a 1 kWe free-piston Stirling engine) using a passive dynamic absorber will be discussed along with the results of a parametric study showing the relationships of Stirling power converter specific weight and efficiency as functions of Stirling engine heater to cooler temperature ratio. Planned tests will be described covering a hydrodynamic gas bearing concept for potential SP-100 application.

Ongoing Analysis of Rocket Based Combined Cycle Engines by the Applied Fluid Dynamics Analysis Group at Marshall Space Flight Center

NASA Technical Reports Server (NTRS)

Ruf, Joseph; Holt, James B.; Canabal, Francisco

1999-01-01

This paper presents the status of analyses on three Rocket Based Combined Cycle configurations underway in the Applied Fluid Dynamics Analysis Group (TD64). TD64 is performing computational fluid dynamics analysis on a Penn State RBCC test rig, the proposed Draco axisymmetric RBCC engine and the Trailblazer engine. The intent of the analysis on the Penn State test rig is to benchmark the Finite Difference Navier Stokes code for ejector mode fluid dynamics. The Draco engine analysis is a trade study to determine the ejector mode performance as a function of three engine design variables. The Trailblazer analysis is to evaluate the nozzle performance in scramjet mode. Results to date of each analysis are presented.

Vapor cycle energy system for implantable circulatory assist devices. Annual progress report Jul 1974--Jun 1975. [Tidal regenerator engine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hagen, K.G.

1975-06-01

The report describes the development status of a heart assist system driven by a nuclear fueled, electronically controlled vapor cycle engine termed the tidal regenerator engine (TRE). The TRE pressurization (typically from 5-160 psia) is controlled by a torque motor coupled to a displacer. The electrical power for the sensor, electronic logic and actuator is provided by a thermoelectric module interposed between the engine superheater and boiler. The TRE is direct coupled to an assist blood pump which also acts as a blood-cooled heat exchanger, pressure-volume transformer and sensor for the electronic logic. Engine efficiencies in excess of 14% havemore » been demonstrated. Efficiency values as high as 13% have been achieved to date.« less

Hot, Hot, Hot Computer Careers.

ERIC Educational Resources Information Center

Basta, Nicholas

1988-01-01

Discusses the increasing need for electrical, electronic, and computer engineers; and scientists. Provides current status of the computer industry and average salaries. Considers computer chip manufacture and the current chip shortage. (MVL)

Predictive Engineering Tools for Injection-Molded Long-Carbon-Fiber Thermoplastic Composites - FY13 Fourth Quarterly Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, Ba Nghiep; Simmons, Kevin L.

2013-12-02

This quarterly report summarizes the status of the project planning to obtain all the approvals required for a Cooperative Research and Development Agreement (CRADA) with Autodesk, Inc., Toyota Motor Engineering and Manufacturing North America (Toyota), and Magna Exterior and Interiors Corporation (Magna). The final CRADA documents processed by PNNL’s Legal Services were submitted to all the parties for signatures.

Nuclear electric propulsion mission engineering study development program and costs estimates, Phase 2 review

NASA Technical Reports Server (NTRS)

1972-01-01

The results are presented of the second six-month performance period of the Nuclear Electric Propulsion Mission Engineering Study. A brief overview of the program, identifying the study objectives and approach, and a discussion of the program status and schedule are presented. The program results are reviewed and key conclusions to date are summarized. Planned effort for the remainder of the program is reviewed.

Ocean Thermal Energy Conversion (OTEC) program. FY 1977 program summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1978-01-01

An overview is given of the ongoing research, development, and demonstration efforts. Each of the DOE's Ocean Thermal Energy Conversion projects funded during fiscal year 1977 (October 1, 1976 through September 30, 1977) is described and each project's status as of December 31, 1977 is reflected. These projects are grouped as follows: program support, definition planning, engineering development, engineering test and evaluation, and advanced research and technology. (MHR)

Knowledge-Acquisition Tool For Expert System

NASA Technical Reports Server (NTRS)

Disbrow, James D.; Duke, Eugene L.; Regenie, Victoria A.

1988-01-01

Digital flight-control systems monitored by computer program that evaluates and recommends. Flight-systems engineers for advanced, high-performance aircraft use knowlege-acquisition tool for expert-system flight-status monitor suppling interpretative data. Interpretative function especially important in time-critical, high-stress situations because it facilitates problem identification and corrective strategy. Conditions evaluated and recommendations made by ground-based engineers having essential knowledge for analysis and monitoring of performances of advanced aircraft systems.

Electromagnetic Pulse (EMP) Handbook for Air Force Communications Service Communications-Electronics-Meteorological Engineers

DTIC Science & Technology

1976-11-01

protec- tion and will require additional measures, such as the application of conductive filter-loaded plastic resins to each joint connection...Lawrence Liver- more Laboratory, Livermore CA, 1974 31. Whitson, A. L., "DCA HEMP Hardness Certification Methodology Status", Stanford Research...of Chief of Engineers, Depot of the Army, December 1971 34. "Development of HEMP Assessment Methodology for Satellite Terminals", Intelcom Rad Tech

DOE/NASA Automotive Stirling Engine Project overview '83

NASA Technical Reports Server (NTRS)

Beremand, D. G.

1982-01-01

An overview of the DOE/NASA Automotive Stirling Engine Project is presented. The background and objectives of the project are reviewed. Project activities are described and technical progress and status are presented and assessed. Prospects for achieving the objective 30% fuel economy improvement are considered good. The key remaining technology issues are primarily related to life, reliability and cost, such as piston rod seals, and low cost heat exchanges.

ETR CONTROL BUILDING, TRA647, INTERIOR. CONTROL ROOM, CONTEXTUAL VIEW. INSTRUMENT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ETR CONTROL BUILDING, TRA-647, INTERIOR. CONTROL ROOM, CONTEXTUAL VIEW. INSTRUMENT PANELS AT REAR OF OPERATOR'S CONSOLE GAVE OPERATOR STATUS OF REACTOR PERFORMANCE, COOLANT-WATER CHARACTERISTICS AND OTHER INDICATORS. WINDOWS AT RIGHT LOOKED INTO ETR BUILDING FIRST FLOOR. CAMERA FACING EAST. INL NEGATIVE NO. HD42-6. Mike Crane, Photographer, 3/2004 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

A Descriptive Analysis of Programs and Trends in Engineering Education for Ethnic Minority Students: A Report to the Field.

ERIC Educational Resources Information Center

Gordon, Edmund W.; And Others

This report presents the findings of an evaluative study of the current status of engineering education for minority students at the collegiate and pre-collegiate levels in the United States. It is based on a survey of 50 existing programs and a review of the professional and research literature in this field. The major findings of the analysis…

Testing of the NASA Hypersonics Project Combined Cycle Engine Large Scale Inlet Mode Transition Experiment (CCE LlMX)

NASA Technical Reports Server (NTRS)

Saunders, J. D.; Stueber, T. J.; Thomas, S. R.; Suder, K. L.; Weir, L. J.; Sanders, B. W.

2012-01-01

Status on an effort to develop Turbine Based Combined Cycle (TBCC) propulsion is described. This propulsion technology can enable reliable and reusable space launch systems. TBCC propulsion offers improved performance and safety over rocket propulsion. The potential to realize aircraft-like operations and reduced maintenance are additional benefits. Among most the critical TBCC enabling technologies are: 1) mode transition from turbine to scramjet propulsion, 2) high Mach turbine engines and 3) TBCC integration. To address these TBCC challenges, the effort is centered on a propulsion mode transition experiment and includes analytical research. The test program, the Combined-Cycle Engine Large Scale Inlet Mode Transition Experiment (CCE LIMX), was conceived to integrate TBCC propulsion with proposed hypersonic vehicles. The goals address: (1) dual inlet operability and performance, (2) mode-transition sequences enabling a switch between turbine and scramjet flow paths, and (3) turbine engine transients during transition. Four test phases are planned from which a database can be used to both validate design and analysis codes and characterize operability and integration issues for TBCC propulsion. In this paper we discuss the research objectives, features of the CCE hardware and test plans, and status of the parametric inlet characterization testing which began in 2011. This effort is sponsored by the NASA Fundamental Aeronautics Hypersonics project

Requirements, Verification, and Compliance (RVC) Database Tool

NASA Technical Reports Server (NTRS)

Rainwater, Neil E., II; McDuffee, Patrick B.; Thomas, L. Dale

2001-01-01

This paper describes the development, design, and implementation of the Requirements, Verification, and Compliance (RVC) database used on the International Space Welding Experiment (ISWE) project managed at Marshall Space Flight Center. The RVC is a systems engineer's tool for automating and managing the following information: requirements; requirements traceability; verification requirements; verification planning; verification success criteria; and compliance status. This information normally contained within documents (e.g. specifications, plans) is contained in an electronic database that allows the project team members to access, query, and status the requirements, verification, and compliance information from their individual desktop computers. Using commercial-off-the-shelf (COTS) database software that contains networking capabilities, the RVC was developed not only with cost savings in mind but primarily for the purpose of providing a more efficient and effective automated method of maintaining and distributing the systems engineering information. In addition, the RVC approach provides the systems engineer the capability to develop and tailor various reports containing the requirements, verification, and compliance information that meets the needs of the project team members. The automated approach of the RVC for capturing and distributing the information improves the productivity of the systems engineer by allowing that person to concentrate more on the job of developing good requirements and verification programs and not on the effort of being a "document developer".

A bill to amend title 38, United States Code, to provide additional educational assistance under Post-9/11 Educational Assistance to veterans pursuing a degree in science, technology, engineering, math, or an area that leads to employment in a high-demand occupation, and for other purposes.

THOMAS, 113th Congress

Sen. Brown, Sherrod [D-OH

2013-03-11

Senate - 06/12/2013 Committee on Veterans' Affairs. Hearings held. Hearings printed: S.Hrg. 113-111. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

A bill to amend the Energy Independence and Security Act of 2007 to authorize the Secretary of Energy to conduct research, development, and demonstration to make biofuels more compatible with small nonroad engines, and for other purposes.

THOMAS, 111th Congress

Sen. Collins, Susan M. [R-ME

2009-03-30

Senate - 12/08/2009 Committee on Energy and Natural Resources Subcommittee on Energy. Hearings held. With printed Hearing: S.Hrg. 111-330. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Reusable rocket engine turbopump condition monitoring

NASA Technical Reports Server (NTRS)

Hampson, M. E.

1984-01-01

Significant improvements in engine readiness with reductions in maintenance costs and turn-around times can be achieved with an engine condition monitoring systems (CMS). The CMS provides health status of critical engine components, without disassembly, through monitoring with advanced sensors. Engine failure reports over 35 years were categorized into 20 different modes of failure. Rotor bearings and turbine blades were determined to be the most critical in limiting turbopump life. Measurement technologies were matched to each of the failure modes identified. Three were selected to monitor the rotor bearings and turbine blades: the isotope wear detector and fiberoptic deflectometer (bearings), and the fiberoptic pyrometer (blades). Signal processing algorithms were evaluated for their ability to provide useful health data to maintenance personnel. Design modifications to the Space Shuttle Main Engine (SSME) high pressure turbopumps were developed to incorporate the sensors. Laboratory test fixtures have been designed for monitoring the rotor bearings and turbine blades in simulated turbopump operating conditions.

Tissue Engineering of Blood Vessels: Functional Requirements, Progress, and Future Challenges.

PubMed

Kumar, Vivek A; Brewster, Luke P; Caves, Jeffrey M; Chaikof, Elliot L

2011-09-01

Vascular disease results in the decreased utility and decreased availability of autologus vascular tissue for small diameter (< 6 mm) vessel replacements. While synthetic polymer alternatives to date have failed to meet the performance of autogenous conduits, tissue-engineered replacement vessels represent an ideal solution to this clinical problem. Ongoing progress requires combined approaches from biomaterials science, cell biology, and translational medicine to develop feasible solutions with the requisite mechanical support, a non-fouling surface for blood flow, and tissue regeneration. Over the past two decades interest in blood vessel tissue engineering has soared on a global scale, resulting in the first clinical implants of multiple technologies, steady progress with several other systems, and critical lessons-learned. This review will highlight the current inadequacies of autologus and synthetic grafts, the engineering requirements for implantation of tissue-engineered grafts, and the current status of tissue-engineered blood vessel research.

Conventional engine technology. Volume 2: Status of diesel engine technology

NASA Technical Reports Server (NTRS)

Schneider, H. W.

1981-01-01

The engines of diesel cars marketed in the United States were examined. Prominent design features, performance characteristics, fuel economy and emissions data were compared. Specific problems, in particular those of NO and smoke emissions, the effects of increasing dieselization on diesel fuel price and availability, current R&D work and advanced diesel concepts are discussed. Diesel cars currently have a fuel economy advantage over gasoline engine powered cars. Diesel drawbacks (noise and odor) were reduced to a less objectionable level. An equivalent gasoline engine driveability was obtained with turbocharging. Diesel manufacturers see a growth in the diesel market for the next ten years. Uncertainties regarding future emission regulation may inhibit future diesel production investments. With spark ignition engine technology advancing in the direction of high compression ratios, the fuel economy advantages of the diesel car is expected to diminish. To return its fuel economy lead, the diesel's potential for future improvement must be used.

76 FR 24923 - National Science Board; Sunshine Act Meetings; Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-03

...: Some portions open, some portions closed. UPDATES: Please refer to the National Science Board Web site... Information Item: Status Deep Underground Science and Engineering Laboratory Information Item: High...

30 cm Engineering Model thruster design and qualification tests

NASA Technical Reports Server (NTRS)

Schnelker, D. E.; Collett, C. R.

1975-01-01

Development of a 30-cm mercury electron bombardment Engineering Model ion thruster has successfully brought the thruster from the status of a laboratory experimental device to a point approaching flight readiness. This paper describes the development progress of the Engineering Model (EM) thruster in four areas: (1) design features and fabrication approaches, (2) performance verification and thruster to thruster variations, (3) structural integrity, and (4) interface definition. The design of major subassemblies, including the cathode-isolator-vaporizer (CIV), main isolator-vaporizer (MIV), neutralizer isolator-vaporizer (NIV), ion optical system, and discharge chamber/outer housing is discussed along with experimental results.

A review of Soviet plasma engine development

NASA Technical Reports Server (NTRS)

Barnett, John W.

1990-01-01

The Soviet Union has maintained a substantial and successful electric propulsion research and development effort since the 1950s; however, American researchers are generally unfamiliar with the Soviet accomplishments. Sources of information about Soviet electric propulsion research are noted. The development of plasma engines, a subset of the electric propulsion effort, is reviewed using numerous Soviet sources. The operational principles and status of several engines of the closed electron drift and high-current types are discussed. With recognition of the limited knowledge of the current Soviet program, the Soviet and American programs are compared, revealing some differences in program formulation and emphasis.

Development of a Thermoacoustic Stirling Engine Technology Demonstrator

NASA Astrophysics Data System (ADS)

Reissner, Alexander; Gerger, Joachim; Hummel, Stefan; Reißig, Jannis; Pawelke, Roland

2014-08-01

Waste heat is a primary source of energy loss in many aerospace and terrestrial applications. FOTEC, an Austrian Research Company located in Wiener Neustadt, is presently developing a micro power converter, promising high efficiencies even for small- scale applications. The converter is based on an innovative thermoacoustic stirling engine concept without any moving parts. Such a maintenance-free engine system would be particularly suitable for advanced space power systems (radioisotope, waste heat) or even within the scope of terrestrial energy harvesting. This paper will summarizes the status of our ongoing efforts on this micro power converter technology.

Education of biomedical engineering in Taiwan.

PubMed

Lin, Kang-Ping; Kao, Tsair; Wang, Jia-Jung; Chen, Mei-Jung; Su, Fong-Chin

2014-01-01

Biomedical Engineers (BME) play an important role in medical and healthcare society. Well educational programs are important to support the healthcare systems including hospitals, long term care organizations, manufacture industries of medical devices/instrumentations/systems, and sales/services companies of medical devices/instrumentations/system. In past 30 more years, biomedical engineering society has accumulated thousands people hold a biomedical engineering degree, and work as a biomedical engineer in Taiwan. Most of BME students can be trained in biomedical engineering departments with at least one of specialties in bioelectronics, bio-information, biomaterials or biomechanics. Students are required to have internship trainings in related institutions out of campus for 320 hours before graduating. Almost all the biomedical engineering departments are certified by IEET (Institute of Engineering Education Taiwan), and met the IEET requirement in which required mathematics and fundamental engineering courses. For BMEs after graduation, Taiwanese Society of Biomedical Engineering (TSBME) provides many continue-learning programs and certificates for all members who expect to hold the certification as a professional credit in his working place. In current status, many engineering departments in university are continuously asked to provide joint programs with BME department to train much better quality students. BME is one of growing fields in Taiwan.

Uprated OMS Engine Status-Sea Level Testing Results

NASA Technical Reports Server (NTRS)

Bertolino, J. D.; Boyd, W. C.

1990-01-01

The current Space Shuttle Orbital Maneuvering Engine (OME) is pressure fed, utilizing storable propellants. Performance uprating of this engine, through the use of a gas generator driven turbopump to increase operating pressure, is being pursued by the NASA Johnson Space Center (JSC). Component level design, fabrication, and test activities for this engine system have been on-going since 1984. More recently, a complete engine designated the Integrated Component Test Bed (ICTB), was tested at sea level conditions by Aerojet. A description of the test hardware and results of the sea level test program are presented. These results, which include the test condition operating envelope and projected performance at altitude conditions, confirm the capability of the selected Uprated OME (UOME) configuration to meet or exceed performance and operational requirements. Engine flexibility, demonstrated through testing at two different operational mixture ratios, along with a summary of projected Space Shuttle performance enhancements using the UOME, are discussed. Planned future activities, including ICTB tests at simulated altitude conditions, and recommendations for further engine development, are also discussed.

The pipeline still leaks and more than you think: a status report on gender diversity in biomedical engineering.

PubMed

Chesler, Naomi C; Barabino, Gilda; Bhatia, Sangeeta N; Richards-Kortum, Rebecca

2010-05-01

While the percentage of women in biomedical engineering is higher than in many other technical fields, it is far from being in proportion to the US population. The decrease in the proportion of women and underrepresented minorities in biomedical engineering from the bachelors to the masters to the doctoral levels is evidence of a still leaky pipeline in our discipline. In addition, the percentage of women faculty members at the assistant, associate and full professor levels remain disappointingly low even after years of improved recruitment of women into biomedical engineering at the undergraduate level. Worse, the percentage of women graduating with undergraduate degrees in biomedical engineering has been decreasing nationwide for the most recent three year span for which national data are available. Increasing diversity in biomedical engineering is predicted to have significant research and educational benefits. The barriers to women's success in biomedical engineering and strategies for overcoming these obstacles-and fixing the leaks in the pipeline-are reviewed.

Metabolic engineering approaches for production of biochemicals in food and medicinal plants.

PubMed

Wilson, Sarah A; Roberts, Susan C

2014-04-01

Historically, plants are a vital source of nutrients and pharmaceuticals. Recent advances in metabolic engineering have made it possible to not only increase the concentration of desired compounds, but also introduce novel biosynthetic pathways to a variety of species, allowing for enhanced nutritional or commercial value. To improve metabolic engineering capabilities, new transformation techniques have been developed to allow for gene specific silencing strategies or stacking of multiple genes within the same region of the chromosome. The 'omics' era has provided a new resource for elucidation of uncharacterized biosynthetic pathways, enabling novel metabolic engineering approaches. These resources are now allowing for advanced metabolic engineering of plant production systems, as well as the synthesis of increasingly complex products in engineered microbial hosts. The status of current metabolic engineering efforts is highlighted for the in vitro production of paclitaxel and the in vivo production of β-carotene in Golden Rice and other food crops. Copyright © 2014 Elsevier Ltd. All rights reserved.

75 FR 10548 - Notice of Intent To Request Revision From the Office of Management and Budget of a Currently...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-08

...The FAA invites public comments about our intention to request the Office of Management and Budget (OMB) to approve a current information collection. The date of manufacture and compliance status stamped on a nameplate of each turbojet engine permits rapid determination by FAA inspectors, owners, and operators whether an engine can legally be installed and operated on an aircraft in the United States.

Intensive plantation culture: 12 years research

Treesearch

Edward A. Hansen

1983-01-01

A collection of papers summarize the status of knowledge for growing hybrid poplars in a short rotation intensively cultured system. The research included studies of propagation, physiology, culture, engineering, insects and diseases, and economics.

Concentrating Solar Power Projects | Concentrating Solar Power | NREL

Science.gov Websites

construction, or under development. CSP technologies include parabolic trough, linear Fresnel reflector, power Technology-listing by parabolic trough, linear Fresnel reflector, power tower, or dish/engine systems Status

Current Status of Gene Engineering Cell Therapeutics

PubMed Central

Saudemont, Aurore; Jespers, Laurent; Clay, Timothy

2018-01-01

Ex vivo manipulations of autologous patient’s cells or gene-engineered cell therapeutics have allowed the development of cell and gene therapy approaches to treat otherwise incurable diseases. These modalities of personalized medicine have already shown great promises including product commercialization for some rare diseases. The transfer of a chimeric antigen receptor or T cell receptor genes into autologous T cells has led to very promising outcomes for some cancers, and particularly for hematological malignancies. In addition, gene-engineered cell therapeutics are also being explored to induce tolerance and regulate inflammation. Here, we review the latest gene-engineered cell therapeutic approaches being currently explored to induce an efficient immune response against cancer cells or viruses by engineering T cells, natural killer cells, gamma delta T cells, or cytokine-induced killer cells and to modulate inflammation using regulatory T cells. PMID:29459866

DE-EE0006714 Final Report-Project Icebreaker™

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wagner, Lorry; Karpinski, David; Nagusky, Beth

Project Icebreaker, a 20 Megawatt offshore wind project 8 miles north of Cleveland, OH in Lake Erie, has been under development by the Lake Erie Energy Development Corporation since 2009. Significant development efforts were completed prior to the award of DE-EE0006714 (December 2014). This report describes the status of the work performed under award DE-EE0006714. The work was organized into several categories or tasks. The report presents the status of that work in each of eleven (11) main tasks: 1) State and Federal Permits; 2) Mono Bucket Foundation Engineering; 3) Construction and Installation Engineering; 4) Cable Route Survey; 5) Electricalmore » System Design; 6) Power Off-take; 7) Project Costs and Risk Management; 8) Operations and Maintenance Planning; 9) Domestic Supply Chain Development; 10) Instrumentation Planning; and 11) Department of Energy Review.« less

Manufacturing Methods & Technology Project Execution Report. First Half CY 80

DTIC Science & Technology

1980-08-01

1 80 7371 INTEGRATED BLADE INSPECTION SYSTEM (IBIS) INSPECTION OF TURBINE ENGINE BLADES AND VANES NECESSITATES HIGH ACCURACY. THE EFFORT IS TIME...OPTICAL INSP OF PRINTED CIRCUIT BOARDS OPERATOR FATIGUE ALLOWS MANY BAD PCBSS TO PASS VISUAL INSPECTION . 29 PROJECTS ADDED IN 1ST HALF» CY80...2631 TITLED "CRITICAL ELECTROHAGNETIC INSPECTION PROBLEMS WITHIN THE ARMY." FUTURE STATUS WILL BE INCLUDED IN THE PROJECT STATUS FOR M 80 6350

To amend title 10, United States Code, to authorize the Secretary of Defense to make grants to recognized science and technology secondary schools to support research and development projects at such schools in science, mathematics, engineering, and technology to supplement the national security functions of the Department of Defense.

THOMAS, 111th Congress

Rep. Connolly, Gerald E. [D-VA-11

2009-07-24

House - 01/12/2010 Referred to the Subcommittee on Terrorism, Unconventional Threats and Capabilities. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Rocket engine exhaust plume diagnostics and health monitoring/management during ground testing

NASA Technical Reports Server (NTRS)

Chenevert, D. J.; Meeks, G. R.; Woods, E. G.; Huseonica, H. F.

1992-01-01

The current status of a rocket exhaust plume diagnostics program sponsored by NASA is reviewed. The near-term objective of the program is to enhance test operation efficiency and to provide for safe cutoff of rocket engines prior to incipient failure, thereby avoiding the destruction of the engine and the test complex and preventing delays in the national space program. NASA programs that will benefit from the nonintrusive remote sensed rocket plume diagnostics and related vehicle health management and nonintrusive measurement program are Space Shuttle Main Engine, National Launch System, National Aero-Space Plane, Space Exploration Initiative, Advanced Solid Rocket Motor, and Space Station Freedom. The role of emission spectrometry and other types of remote sensing in rocket plume diagnostics is discussed.

Progreen online engineering diploma in the Middle East: assessment of the educational experience

NASA Astrophysics Data System (ADS)

Baytiyeh, Hoda

2018-03-01

Little is known about the status of online learning in the Middle East. This study investigates educational experiences of engineers enrolled in the new joint online ProGreen diploma programme offered by three universities, two in Lebanon and one in Egypt. Forty-eight working engineers responded to an online survey based on the three components of the community of inquiry model: social presence, teaching presence, and cognitive presence. Exploratory factor analysis identified five factors: sense of belonging, self-directedness, self-actualisation, interaction, and instructional guidance. The findings showed that sense of belonging was the factor engineers rated highest but it did not correlate with instructional guidance. However, instructional guidance highly correlated with self-directedness and self-actualisation.

Civil engineering airman at increased risk for injuries and injury-related musculoskeletal disorders.

PubMed

Webb, Timothy S; Wells, Timothy S

2011-03-01

With the advent of electronic records, the opportunity to conduct research on workplace-related injuries and musculoskeletal disorders has increased dramatically. The purpose of this study was to examine the United States Air Force Civil Engineering career field to determine if they are negatively impacted by their work environment. Specifically, the objective of this study was to determine if enlisted Civil Engineering Airmen (n = 25,385) were at increased risk for injury or injury-related musculoskeletal disorders compared to enlisted Information Management/Communications Airmen (n = 28,947). Using an historical prospective design, electronic data were assembled and analyzed using Cox's proportional hazards modeling. Models were stratified by gender and adjusted for race/ethnicity, marital status, birth year, and deployment status. Male Civil Engineers were observed to be at greater risk for both inpatient injury-related musculoskeletal disorders (HR = 1.86; 95% CI = 1.54-2.26) and injuries (HR = 1.77; 95% CI = 1.48-2.11), while female Civil Engineers were more than double the risk for both inpatient injury-related musculoskeletal disorders (HR = 2.18; 95% CI = 1.28-3.73) and injuries (HR = 2.22; 95% CI = 1.27-3.88) compared to Information Management/Communications Airmen. Although analyses do not allow exploration of specific causes, they highlight the utility of using electronic data to identify occupations for further evaluation. Based on these results, additional resources were allocated to survey Civil Engineers on their physical work demands and job requirements to identify key problem areas for further study and mitigation. Copyright © 2010 Wiley-Liss, Inc.

FY2004 SYSTEM ENGINEER PROGRAM MANAGER ANNUAL REPORT

DOE Office of Scientific and Technical Information (OSTI.GOV)

JACKSON, G.J.

2004-10-29

During FY 2004, reviews of the FH System Engineer (SE) Program were conducted by the Independent Assessment (IA) Group. The results of these reviews are summarized as a part of this document. Additional reviews were performed by FH Engineering personnel. SE Engineering reviews performed include Periodic Walkdowns (typically, quarterly) by the SEs, a review of System Notebooks by the System Engineer Program Manager (SEPM), annual status report by each SE, and an annual status report by each of the Project Chief Engineers (PCEs). FY 2004 marked the completion of the first round of Vital Safety System assessments. Each of themore » VSSs on the FH VSS list has been evaluated at least once by either the FH Independent Assessment organization or was included as a part of DOE Phase II assessment. Following the completion of the K-Basins Assessment in May 2004, a review of the VSS assessment process was completed. Criteria were developed by FH, and concurred with by RL, to determine the frequency and priority of future VSS assessments. Additional actions have been taken to increase the visibility and emphasis assigned to VSSs. Completion of several Documented Safety Analyses (DSA), in combination with efforts to remove source term materials from several facilities, enabled the number of systems on the FH VSS list to be reduced from 60 at the beginning of FY 2004 to 48 by the end of FY 2004. It is expected that there will be further changes to the FH VSS list based on additional DSA revisions and continued progress towards reduction of source terms across the Hanford Site. Other new VSSs may be added to the list to reflect the relocation of materials away from the River Corridor to interim storage locations on the Central Plateau.« less

Metabolic engineering of folate and its precursors in Mexican common bean (Phaseolus vulgaris L.).

PubMed

Ramírez Rivera, Naty G; García-Salinas, Carolina; Aragão, Francisco J L; Díaz de la Garza, Rocío Isabel

2016-10-01

Folate (vitamin B9) deficiency causes several health problems globally. However, folate biofortification of major staple crops is one alternative that can be used to improve vitamin intakes in populations at risk. We increased the folate levels in common bean by engineering the pteridine branch required for their biosynthesis. GTP cyclohydrolase I from Arabidopsis (AtGchI) was stably introduced into three common bean Pinto cultivars by particle bombardment. Seed-specific overexpression of AtGCHI caused significant increases of up to 150-fold in biosynthetic pteridines in the transformed lines. The pteridine boost enhanced folate levels in raw desiccated seeds by up to threefold (325 μg in a 100 g portion), which would represent 81% of the adult recommended daily allowance. Unexpectedly, the engineering also triggered a general increase in PABA levels, the other folate precursor. This was not observed in previous engineering studies and was probably caused by a feedforward mechanism that remains to be elucidated. Results from this work also show that common bean grains accumulate considerable amounts of oxidized pteridines that might represent products of folate degradation in desiccating seeds. Our study uncovers a probable different regulation of folate homoeostasis in these legume grains than that observed in other engineering works. Legumes are good sources of folates, and this work shows that they can be engineered to accumulate even greater amounts of folate that, when consumed, can improve folate status. Biofortification of common bean with folates and other micronutrients represents a promising strategy to improve the nutritional status of populations around the world. © 2016 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

Heat engine development for solar thermal power systems

NASA Technical Reports Server (NTRS)

Pham, H. Q.; Jaffe, L. D.

1981-01-01

The technical status of three heat engines (Stirling, high-temperature Brayton, and Combined cycle) for use in solar thermal power systems is presented. Performance goals necessary to develop a system competitive with conventional power requirements include an external heated engine output less than 40 kW, and efficiency power conversion subsystem at least 40% at rated output, and a half-power efficiency of at least 37%. Results show that the Stirling engine can offer a 39% efficiency with 100 hours of life, and a 20% efficiency with 10,000 hours of life, but problems with seals and heater heads exist. With a demonstrated efficiency near 31% at 1500 F and a minimum lifetime of 100,000 hours, the Brayton engine does not offer sufficient engine lifetime, efficiency, and maintenance for solar thermal power systems. Examination of the Rankine bottoming cycle of the Combined cycle engine reveals a 30 year lifetime, but a low efficiency. Additional development of engines for solar use is primarily in the areas of components to provide a long lifetime, high reliability, and low maintenance (no more than $0.001/kW-hr).

Effects of Gender on Engineering Career Commitment

NASA Astrophysics Data System (ADS)

Barker, Anne M.

Engineering has been one of the most difficult fields for 'women to enter and in which to succeed. Although the percentage of female engineers has Increased, women are still seriously underrcpresented in the workforce. This study examined the effect offender on career commitment, success, satisfaction, and involvement in engineering, and the effect of personality and work environment on these variables. Alumni from an engineering school in the northeastern United States were surveyed. The questionnaire was analyzed using statistical and descriptive methods to determine relationships among these variables. Women's commitment scores were lower than men's when controlled for other variables, including satisfaction and involvement. Men had longer tenure as engineers than women, even when controlled for year of graduation, professional engineering status, and number of children. Women did not leave engineering in different proportions than men, but they did earn significantly less despite controlling for year of graduation and number of hours worked weekly. Some gender differences in workplace experience were also found, including having colleagues act protectively, being mistaken for secretaries, and seeing men progress faster in their careers than equally qualified women.

Next-Generation RS-25 Engines for the NASA Space Launch System

NASA Technical Reports Server (NTRS)

Ballard, Richard O.

2017-01-01

The utilization of heritage RS-25 engines, also known as the Space Shuttle Main Engine (SSME), has enabled rapid progress in the development and certification of the NASA Space Launch System (SLS) toward operational flight status. The RS-25 brings design maturity and extensive experience gained through 135 missions, 3000+ ground tests, and over 1 million seconds total accumulated hot-fire time. In addition, there were also 16 flight engines and 2 development engines remaining from the Space Shuttle program that could be leveraged to support the first four flights. Beyond these initial SLS flights, NASA must have a renewed supply of RS-25 engines that must reflect program affordability imperatives as well as technical requirements imposed by the SLS Block-1B vehicle (i.e., 111% RPL power level, reduced service life). Recognizing the long lead times needed for the fabrication, assembly and acceptance testing of flight engines, design activities are underway to improve system affordability and eliminate obsolescence concerns. These key objectives are enabled largely by utilizing modern materials and fabrication technologies, but also by innovations in systems engineering and integration (SE&I) practices.

Integrated tracking of components by engineering and logistics utilizing logistics asset tracking system

NASA Technical Reports Server (NTRS)

Renfroe, Michael B.; Mcdonald, Edward J.; Bradshaw, Kimberly

1988-01-01

The Logistics Asset Tracking System (LATS) devised by NASA contains data on Space Shuttle LRUs that are daily updated to reflect such LRU status changes as repair due to failure or modification due to changing engineering requirements. The implementation of LATS has substantially increased personnel responsiveness, preventing costly delays in Space Shuttle processing and obviating hardware cannibalization. An evaluation is presented of LATS achievements in the direction of an integrated logistical support posture.

Engineering the Organization: Is USACE Doing it Right

DTIC Science & Technology

2015-05-23

long as they serve "on active duty in a pay status".105 Furthermore, the law does not require soldiers to abide by the standard forty- hour workweek ...of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources...MM-YYYY) 15-03-2015 2. REPORT TYPE Master’s Thesis 3. DATES COVERED (From - To) JUN 2014 – MAY 2015 4 . TITLE AND SUBTITLE Engineering the

Predictive Engineering Tools for Injection-Molded Long-Carbon-Fiber Thermoplastic Composites - FY13 Third Quarterly Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nguyen, Ba Nghiep; Simmons, Kevin L.

2013-08-06

This quarterly report summarizes the status for the project planning to obtain all the approvals required for a Cooperative Research and Development Agreement (CRADA) with Autodesk, Inc., Toyota Motor Engineering and Manufacturing North America (Toyota), and Magna Exterior and Interiors Corporation (Magna). The CRADA documents have been processed by PNNL Legal Services that is also coordinating the revision effort with the industrial parties to address DOE’s comments.

Foreign Science and Engineering Presence in U.S. Institutions and the Labor Force

DTIC Science & Technology

2007-01-12

physical therapists . The application for H-1B status must be filed by an employer; an individual cannot obtain an H-1B visa on his or her own...scientist or engineer for permanent residence, if they meet terms established by the Immigration and Nationality Act. 3Foreign students planning to remain...56%; for physical sciences, 64%; life sciences, 63%; mathematics, 57%; computer sciences, 63%; and agricultural sciences, 38%. Stay rates are not

An Analysis of the Management of RED HORSE (Rapid Engineering Deployable, Heavy Operational Repair Squadron, Engineer) Construction Projects

DTIC Science & Technology

1987-09-01

folder . 4. Reviewing design documents and supervises project if designed by other than RED HORSE. 5. Chairing design conferences. 6. Coordinating design...project folder . Air Force Regulation 93-9 requires the project manager to maintain the following records: A. Approved project programming documents. B...these records are maintained in the project folder . Depending on the current status of the project, the project folder will be available from either the

DOE/NASA Automotive Stirling Engine Project Overview 83

NASA Technical Reports Server (NTRS)

Beremand, D. G.

1983-01-01

An overview of the DOE/NASA Automotive Stirling Engine Project is presented. The background and objectives of the project are reviewed. Project activities are described and technical progress and status are presented and assessed. Prospects for achieving the objective 30 percent fuel economy improvement are considered good. The key remaining technology issues are primarily related to life, reliability and cost, such as piston rod seals, and low cost heat exchanges. Previously announced in STAR as N83-27924

Flight Test of Propulsion Monitoring and Diagnostic System

NASA Technical Reports Server (NTRS)

Gabel, Steve; Elgersma, Mike

2002-01-01

The objective of this program was to perform flight tests of the propulsion monitoring and diagnostic system (PMDS) technology concept developed by Honeywell under the NASA Advanced General Aviation Transport Experiment (AGATE) program. The PMDS concept is intended to independently monitor the performance of the engine, providing continuous status to the pilot along with warnings if necessary as well as making the data available to ground maintenance personnel via a special interface. These flight tests were intended to demonstrate the ability of the PMDS concept to detect a class of selected sensor hardware failures, and the ability to successfully model the engine for the purpose of engine diagnosis.

Update of the development on the new Audi NSU rotary engine generation

DOE Office of Scientific and Technical Information (OSTI.GOV)

van Basshuysen, R.; Wilmers, G.

At AUDI NSU a new generation of rotary engines has been developed of which the significant layout parameters are outlined. The present status of development is characterized by a lean burn concept with fuel injection and an exhaust emission control system with catalytic converter. Test results indicate that the fuel economy ranges at the same level as comparable reciprocating engines. The future US-exhaust emission standards are kept below but in respect to the Japanese standards further reduction of NO/sub x/ is necessary. Endurance tests proving the durability of the exhaust emission control system have still to be performed.

3D printed porous ceramic scaffolds for bone tissue engineering: a review.

PubMed

Wen, Yu; Xun, Sun; Haoye, Meng; Baichuan, Sun; Peng, Chen; Xuejian, Liu; Kaihong, Zhang; Xuan, Yang; Jiang, Peng; Shibi, Lu

2017-08-22

This study summarizes the recent research status and development of three-dimensional (3D)-printed porous ceramic scaffolds in bone tissue engineering. Recent literature on 3D-printed porous ceramic scaffolds was reviewed. Compared with traditional processing and manufacturing technologies, 3D-printed porous ceramic scaffolds have obvious advantages, such as enhancement of the controllability of the structure or improvement of the production efficiency. More sophisticated scaffolds were fabricated by 3D printing technology. 3D printed bioceramics have broad application prospects in bone tissue engineering. Through understanding the advantages and limitations of different 3D-printing approaches, new classes of bone graft substitutes can be developed.

Wetlands Research Program. Corps of Engineers Wetlands Delineation Manual. Appendix C. Sections 1 and 2. Region 4 - North Plains.

DTIC Science & Technology

1987-01-01

wetlands, are as follows: Category Symbol Definition OBLIGATE WETLAND OBL Plants that occur almost always PLANTS (estimated probability >.992) in...estimated probability 1% to 33%) in nonwetlands. FACULTATIVE PLANTS FAC Plants with a similar likelihood (estimated probability 337 to 67%) of... Symbols Symbols appearing in the list under the indicator status column are as follows: +: A "+" sign following an indicator status denotes that the

Current MBDA R&T Effort on Ram/Scramjet and Detonation Wave Engine

DTIC Science & Technology

2006-05-01

13] to[18]), • WRR program (MBDA France and MAI) ([19] to[23]), • PROMETHEE program (ONERA and MBDA France) ([24] to [27]), Current MBDA R&T...significant step passed for technology and combustion processes mastering - AIAA-2003-7004. [24] F. FALEMPIN, L. SERRE The French PROMETHEE Program...status in 2000 - AIAA – 2000 – 3341 [25] L.SERRE, F. FALEMPIN The French PROMETHEE Program on hydrocarbon fueled dual-mode ramjet–status in 2001

Locomotive Emission and Engine Idle Reduction Technology Demonstration Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

John R. Archer

2005-03-14

In response to a United States Department of Energy (DOE) solicitation, the Maryland Energy Administration (MEA), in partnership with CSX Transportation, Inc. (CSXT), submitted a proposal to DOE to support the demonstration of Auxiliary Power Unit (APU) technology on fifty-six CSXT locomotives. The project purpose was to demonstrate the idle fuel savings, the Nitrous Oxide (NOX) emissions reduction and the noise reduction capabilities of the APU. Fifty-six CSXT Baltimore Division locomotives were equipped with APUs, Engine Run Managers (ERM) and communications equipment to permit GPS tracking and data collection from the locomotives. Throughout the report there is mention of themore » percent time spent in the State of Maryland. The fifty-six locomotives spent most of their time inside the borders of Maryland and some spent all their time inside the state borders. Usually when a locomotive traveled beyond the Maryland State border it was into an adjoining state. They were divided into four groups according to assignment: (1) Power Unit/Switcher Mate units, (2) Remote Control units, (3) SD50 Pusher units and (4) Other units. The primary data of interest were idle data plus the status of the locomotive--stationary or moving. Also collected were main engine off, idling or working. Idle data were collected by county location, by locomotive status (stationary or moving) and type of idle (Idle 1, main engine idling, APU off; Idle 2, main engine off, APU on; Idle 3, main engine off, APU off; Idle 4, main engine idle, APU on). Desirable main engine idle states are main engine off and APU off or main engine off and APU on. Measuring the time the main engine spends in these desirable states versus the total time it could spend in an engine idling state allows the calculation of Percent Idle Management Effectiveness (%IME). IME is the result of the operation of the APU plus the implementation of CSXT's Warm Weather Shutdown Policy. It is difficult to separate the two. The units demonstrated an IME of 64% at stationary idle for the test period. The data collected during calendar year 2004 demonstrated that 707,600 gallons of fuel were saved and 285 tons of NOX were not emitted as a result of idle management in stationary idle, which translates to 12,636 gallons and 5.1 tons of NOx per unit respectively. The noise reduction capabilities of the APU demonstrated that at 150 feet from the locomotive the loaded APU with the main engine shut down generated noise that was only marginally above ambient noise level.« less

Current Status of Engineering Education in America

NASA Astrophysics Data System (ADS)

Barr, Ronald E.

Many faculty believe that engineering education in America is at a crossroads and much change is needed. International competition in engineering and the global economy have major potential impact on the engineering workforce of the future. We must find ways to educate U.S. engineers to be competitive and creative contributors in the worldwide arena. Recent national reports are sounding the alarm that the U.S. is losing it leadership in technology and innovation, with consequences for economic prosperity and national security. The report Rising Above the Gathering Storm discusses this dilemma in detail and offers four recommendations to U.S. policymakers. The report Educating the Engineer of 2020 discusses new ways to prepare American engineers for the 21st Century. Furthermore, changes in ABET accreditation, along with new paradigms of teaching and new technology in the classroom, are changing the scholarship of engineering education. We must find ways to promote change in engineering faculty for this new opportunity in engineering educational scholarship. Future engineering students are now in K-12, which is becoming an increasingly diverse population that in the past has not been fully represented in engineering education. Current trends show disaffection for pursuing studies in science and engineering in the youth of our U.S. society. We must find new ways to portray engineering as an exciting and rewarding career, and certainly as an educational platform for professional careers beyond the baccalaureate degree.

Genetic engineering for skeletal regenerative medicine.

PubMed

Gersbach, Charles A; Phillips, Jennifer E; García, Andrés J

2007-01-01

The clinical challenges of skeletal regenerative medicine have motivated significant advances in cellular and tissue engineering in recent years. In particular, advances in molecular biology have provided the tools necessary for the design of gene-based strategies for skeletal tissue repair. Consequently, genetic engineering has emerged as a promising method to address the need for sustained and robust cellular differentiation and extracellular matrix production. As a result, gene therapy has been established as a conventional approach to enhance cellular activities for skeletal tissue repair. Recent literature clearly demonstrates that genetic engineering is a principal factor in constructing effective methods for tissue engineering approaches to bone, cartilage, and connective tissue regeneration. This review highlights this literature, including advances in the development of efficacious gene carriers, novel cell sources, successful delivery strategies, and optimal target genes. The current status of the field and the challenges impeding the clinical realization of these approaches are also discussed.

Gas turbine engines and transmissions for bus demonstration programs. Technical status report, 31 July 1979--31 October 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nigro, D.N.

1979-11-01

The report summarizes the DDA activities for the effort performed on the procurement and delivery of eleven Allison GT 404-4 gas turbine engines and five HT740CT and six V730CT Allison automatic transmissions and the required associated software. The contract requires the delivery of the engines and transmissions for the Greyhound and Transit Coaches, respectively. In addition, software items such as cost reports, technical reports, installation drawings, acceptance test data and parts lists are required. A recent decision by the DOE will modify the build configuration for the last four (4) Transit Coach engines. It was decided by the DOE atmore » a meeting in Washington, DC on March 28, 1979 with representatives from DDA, NASA/LeRC, JPL and Booz-Allen and Hamilton that these engines are to be built with ceramic regenerators. (TFD)« less

Design of lightning protection for a full-authority digital engine control

NASA Technical Reports Server (NTRS)

Dargi, M.; Rupke, E.; Wiles, K.

1991-01-01

The steps and procedures are described which are necessary to achieve a successful lightning-protection design for a state-of-the-art Full-Authority Digital Engine Control (FADEC) system. The engine and control systems used as examples are fictional, but the design and verification methods are real. Topics discussed include: applicable airworthiness regulation, selection of equipment transient design and control levels for the engine/airframe and intra-engine segments of the system, the use of cable shields, terminal-protection devices and filter circuits in hardware protection design, and software approaches to minimize upset potential. Shield terminations, grounding, and bonding are also discussed, as are the important elements of certification and test plans, and the role of tests and analyses. Also included are examples of multiple-stroke and multiple-burst testing. A review of design pitfalls and challenges, and status of applicable test standards such as RTCA DO-160, Section 22, are presented.

Vapor cycle energy system for implantable circulatory assist devices. Annual progress report, Jul 1975--May 1976

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watelet, R.P.; Ruggles, A.E.; Hagen, K.G.

1976-05-01

The development status of a heart assist system driven by a nuclear fueled, electronically controlled vapor cycle engine termed the tidal regenerator engine (TRE) is described. The TRE pressurization is controlled by a torque motor coupled to a displacer. The electrical power for the sensor, electronic logic and actuator is provided by thermoelectric modules interposed between the engine superheater and boiler. The TRE is direct coupled to an assist blood pump which also acts as a blood-cooled heat exchanger, pressure-volume transformer and sensor for the electronic logic. Engine cycle efficiency in excess of 14% has been demonstrated routinely. Overall systemmore » efficiency on 33 watts of over 9% has been demonstrated. A binary version of this engine in the annular configuration is now being tested. The preliminary tests demonstrated 10% cycle efficiency on the first buildup which ran well and started easily.« less

Vapor cycle energy system for implantable circulatory assist devices. Annual report, Jul 1973-Jul 1974

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hagen, K.G.

1974-08-01

The report describes the development status of a heart assist system driven by a nuclear fueled, electronically controlled vapor cycle engine termed the tidal regenerator engine (TRE). The TRE pressurization (typically from 5-160 psia) is controlled by a torque motor coupled to a displacer. The electrical power for the sensor, electronic logic and actuator is provided by a thermoelectric module interposed between the engine superheater and boiler. The TRE is directly coupled to an assist blood pump which also acts as a blood-cooled heat exchanger, pressure-volume transformer and sensor for the electronic logic. Engine efficiencies in excess of 10 percentmore » have been demonstrated. A binary version of the engine with twice the potential efficiency is being investigated. Efficiency values as high as 13 percent have been achieved to date. (GRA)« less

Development Status and Performance Comparisons of Environmental Barrier Coating Systems for SiCSiC Ceramic Matrix Composites

NASA Technical Reports Server (NTRS)

Zhu, Dongming; Harder, Bryan

2016-01-01

Environmental barrier coatings (EBC) and SiCSiC ceramic matrix composites (CMCs) will play a crucial role in future aircraft turbine engine systems, because of their ability to significantly increase engine operating temperatures, reduce engine weight and cooling requirements. This paper presents current NASA EBC-CMC development emphases including: the coating composition and processing improvements, laser high heat flux-thermal gradient thermo-mechanical fatigue - environmental testing methodology development, and property evaluations for next generation EBC-CMC systems. EBCs processed with various deposition techniques including Plasma Spray, Electron Beam - Physical Vapor Deposition, and Plasma Spray Physical Vapor Deposition (PS-PVD) will be particularly discussed. The testing results and demonstrations of advanced EBCs-CMCs in complex simulated engine thermal gradient cyclic fatigue, oxidizing-steam and CMAS environments will help provide insights into the coating development strategies to meet long-term engine component durability goals.

A Report on the Present Status of Engineering Mathematics Test (EMaT)

NASA Astrophysics Data System (ADS)

Watanabe, Toshimasa; Takafuji, Daisuke

The aim of Engineering Mathematics Test (EMaT) is to make sure what essentials in curriculum of Engineering Mathematics is, and to assess university students’ core academic competence and achievement of Engineering Mathematics, helping assurance of students’ academic ability. It is useful for professors to evaluate teaching effect of the classes, and this evaluation would help them improve curricula. Scores can be available for both graduate school entrance examinations and employment tests, leading to selecting persons with basic academic ability in Engineering Mathematics. The scope includes fundamentals in Calculus, Linear Algebra, Differential Equations, and Probability and Statistics. It is open to all students free of charge, and is annually given once in December. In 2007, 2,396 students from 35 universities took EMaT, and the total number of students who have taken EMaT in these 5 years is 6,240.

A demonstration of an intelligent control system for a reusable rocket engine

NASA Technical Reports Server (NTRS)

Musgrave, Jeffrey L.; Paxson, Daniel E.; Litt, Jonathan S.; Merrill, Walter C.

1992-01-01

An Intelligent Control System for reusable rocket engines is under development at NASA Lewis Research Center. The primary objective is to extend the useful life of a reusable rocket propulsion system while minimizing between flight maintenance and maximizing engine life and performance through improved control and monitoring algorithms and additional sensing and actuation. This paper describes current progress towards proof-of-concept of an Intelligent Control System for the Space Shuttle Main Engine. A subset of identifiable and accommodatable engine failure modes is selected for preliminary demonstration. Failure models are developed retaining only first order effects and included in a simplified nonlinear simulation of the rocket engine for analysis under closed loop control. The engine level coordinator acts as an interface between the diagnostic and control systems, and translates thrust and mixture ratio commands dictated by mission requirements, and engine status (health) into engine operational strategies carried out by a multivariable control. Control reconfiguration achieves fault tolerance if the nominal (healthy engine) control cannot. Each of the aforementioned functionalities is discussed in the context of an example to illustrate the operation of the system in the context of a representative failure. A graphical user interface allows the researcher to monitor the Intelligent Control System and engine performance under various failure modes selected for demonstration.

Concentrating Solar Power Projects - Tooele Army Depot | Concentrating

Science.gov Websites

: Dish/Engine Turbine Capacity: Net: 1.5 MW Gross: 1.5 MW Status: Currently Non-Operational Start Year : Currently Non-Operational Country: United States City: Tooele State: Utah County: Tooele County Lat/Long

75 FR 26321 - Seventeenth Plenary Meeting: RTCA Special Committee 203: Unmanned Aircraft Systems

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-11

... RTCA Workspace Web Tool Special Committee Status Overview Workgroup Updates WG1--Systems Engineering..., Washington, DC 20036; telephone (202) 833-9339; fax (202) 833-9434; Web site http://www.rtca.org...

Gas Turbine Engine Production Implementation Study : Volume 1. Executive Summary.

DOT National Transportation Integrated Search

1973-07-01

The report presents an assessment of available information pertaining to implementing mass production of gas turbine powered automobiles. The status of the technology and implementation schedule visibility reported herein is that existing at the time...

75 FR 8299 - Draft Environmental Impact Statement; Determination of Regulated Status of Alfalfa Genetically...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-24

... Engineered for Tolerance to the Herbicide Glyphosate AGENCY: Animal and Plant Health Inspection Service, USDA... to the herbicide glyphosate. State issued photo identification is required and all bags will be...

75 FR 1585 - Draft Environmental Impact Statement; Determination of Regulated Status of Alfalfa Genetically...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-12

... Engineered for Tolerance to the Herbicide Glyphosate AGENCY: Animal and Plant Health Inspection Service, USDA... to the herbicide glyphosate. State issued photo identification is required and all bags will be...

Reducing highway litter.

DOT National Transportation Integrated Search

2013-06-01

The objective of this report is to evaluate the status of highway litter in the State of Utah. Under the direction of Russ Scovil, engineer with the Utah Department of Transportation (UDOT), researchers at the University of Utah performed a literatur...

Stable Metal–Organic Frameworks with Group 4 Metals: Current Status and Trends

PubMed Central

2018-01-01

Group 4 metal-based metal–organic frameworks (MIV-MOFs), including Ti-, Zr-, and Hf-based MOFs, are one of the most attractive classes of MOF materials owing to their superior chemical stability and structural tunability. Despite being a relatively new field, MIV-MOFs have attracted significant research attention in the past few years, leading to exciting advances in syntheses and applications. In this outlook, we start with a brief overview of the history and current status of MIV-MOFs, emphasizing the challenges encountered in their syntheses. The unique properties of MIV-MOFs are discussed, including their high chemical stability and strong tolerance toward defects. Particular emphasis is placed on defect engineering in Zr-MOFs which offers additional routes to tailor their functions. Photocatalysis of MIV-MOF is introduced as a representative example of their emerging applications. Finally, we conclude with the perspective of new opportunities in synthesis and defect engineering. PMID:29721526

Status of the Boeing Dish Engine Critical Component Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brau, H.W.; Diver, R.B.; Nelving, H.

1999-01-08

The Boeing Company's Dish Engine Critical Component (DECC) project started in April of 1998. It is a continuation of a solar energy program started by McDonnell Douglas (now Boeing) and United Stirling of Sweden in the mid 1980s. The overall objectives, schedule, and status of this project are presented in this paper. The hardware test configuration, hardware background, operation, and test plans are also discussed. A summary is given of the test data, which includes the daily power performance, generated energy, working-gas usage, mirror reflectivity, solar insolation, on-sun track time, generating time, and system availability. The system performance based uponmore » the present test data is compared to test data from the 1984/88 McDonnell Douglas/United Stirling AB/Southem California Edison test program. The test data shows that the present power, energy, and mirror performance is comparable to when the hardware was first manufactured 14 years ago.« less

Status of the Boeing Dish Engine Critical Component project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stone, K.W.; Nelving, H.; Braun, H.W.

1999-07-01

The Boeing Company's Dish Engine Critical Component (DECC) project started in April of 1998. It is a continuation of a solar energy program started by McDonnel Douglas (now Boeing) and United Stirling of Sweden in the mid 1980s. The overall objectives, schedule, and status of this project are presented in this paper. The hardware test configuration, hardware background, operation, and test plans are also discussed. A summary is given of the test data, which includes the daily power performance, generated energy, working-gas usage, mirror reflectivity, solar insolation, on-sun track time. Generating time, and system availability. The system performance based uponmore » the present test data is compared to test data from the 1984/88 McDonnel Douglas/United Stirling AB/Southern California Edison test program. The test data shows that the present power, energy, and mirror performance is comparable to when the hardware was first manufactured 14 years ago.« less

Liquid lubricants for advanced aircraft engines

NASA Technical Reports Server (NTRS)

Loomis, William R.; Fusaro, Robert L.

1993-01-01

An overview of liquid lubricants for use in current and projected high performance turbojet engines is discussed. Chemical and physical properties are reviewed with special emphasis placed on the oxidation and thermal stability requirements imposed upon the lubrication system. A brief history is given of the development of turbine engine lubricants which led to the present day synthetic oils with their inherent modification advantages. The status and state of development of some eleven candidate classes of fluids for use in advanced turbine engines are discussed. Published examples of fundamental studies to obtain a better understanding of the chemistry involved in fluid degradation are reviewed. Alternatives to high temperature fluid development are described. The importance of continuing work on improving current high temperature lubricant candidates and encouraging development of new and improved fluid base stocks are discussed.

Some Observations on the Current Status of Performing Finite Element Analyses

NASA Technical Reports Server (NTRS)

Raju, Ivatury S.; Knight, Norman F., Jr; Shivakumar, Kunigal N.

2015-01-01

Aerospace structures are complex high-performance structures. Advances in reliable and efficient computing and modeling tools are enabling analysts to consider complex configurations, build complex finite element models, and perform analysis rapidly. Many of the early career engineers of today are very proficient in the usage of modern computers, computing engines, complex software systems, and visualization tools. These young engineers are becoming increasingly efficient in building complex 3D models of complicated aerospace components. However, the current trends demonstrate blind acceptance of the results of the finite element analysis results. This paper is aimed at raising an awareness of this situation. Examples of the common encounters are presented. To overcome the current trends, some guidelines and suggestions for analysts, senior engineers, and educators are offered.

Ongoing Analyses of Rocket Based Combined Cycle Engines by the Applied Fluid Dynamics Analysis Group at Marshall Space Flight Center

NASA Technical Reports Server (NTRS)

Ruf, Joseph H.; Holt, James B.; Canabal, Francisco

2001-01-01

This paper presents the status of analyses on three Rocket Based Combined Cycle (RBCC) configurations underway in the Applied Fluid Dynamics Analysis Group (TD64). TD64 is performing computational fluid dynamics (CFD) analysis on a Penn State RBCC test rig, the proposed Draco axisymmetric RBCC engine and the Trailblazer engine. The intent of the analysis on the Penn State test rig is to benchmark the Finite Difference Navier Stokes (FDNS) code for ejector mode fluid dynamics. The Draco analysis was a trade study to determine the ejector mode performance as a function of three engine design variables. The Trailblazer analysis is to evaluate the nozzle performance in scramjet mode. Results to date of each analysis are presented.

Silicon production process evaluations

NASA Technical Reports Server (NTRS)

1981-01-01

Chemical engineering analysis of the HSC process (Hemlock Semiconductor Corporation) for producing silicon from dichlorosilane in a 1,000 MT/yr plant was continued. Progress and status for the chemical engineering analysis of the HSC process are reported for the primary process design engineering activities: base case conditions (85%), reaction chemistry (85%), process flow diagram (60%), material balance (60%), energy balance (30%), property data (30%), equipment design (20%) and major equipment list (10%). Engineering design of the initial distillation column (D-01, stripper column) in the process was initiated. The function of the distillation column is to remove volatile gases (such as hydrogen and nitrogen) which are dissolved in liquid chlorosilanes. Initial specifications and results for the distillation column design are reported including the variation of tray requirements (equilibrium stages) with reflux ratio for the distillation.

Liquid lubricants for advanced aircraft engines

NASA Technical Reports Server (NTRS)

Loomis, William R.; Fusaro, Robert L.

1992-01-01

An overview of liquid lubricants for use in current and projected high performance turbojet engines is discussed. Chemical and physical properties are reviewed with special emphasis placed on the oxidation and thermal stability requirements imposed upon the lubrication system. A brief history is given of the development of turbine engine lubricants which led to the present day synthetic oils with their inherent modification advantages. The status and state of development of some eleven candidate classes of fluids for use in advanced turbine engines are discussed. Published examples of fundamental studies to obtain a better understanding of the chemistry involved in fluid degradation are reviewed. Alternatives to high temperature fluid development are described. The importance of continuing work on improving current high temperature lubricant candidates and encouraging development of new and improved fluid base stocks are discussed.

Latest status of the clinical and industrial applications of cell sheet engineering and regenerative medicine.

PubMed

Egami, Mime; Haraguchi, Yuji; Shimizu, Tatsuya; Yamato, Masayuki; Okano, Teruo

2014-01-01

Cell sheet engineering, which allows tissue engineering to be realized without the use of biodegradable scaffolds as an original approach, using a temperature-responsive intelligent surface, has been applied in regenerative medicine for various tissues, and a number of clinical studies have been already performed for life-threatening diseases. By using the results and findings obtained from the initial clinical studies, additional investigative clinical studies in several tissues with cell sheet engineering are currently in preparation stage. For treating many patients effectively by cell sheet engineering, an automated system integrating cell culture, cell-sheet fabrication, and layering is essential, and the system should include an advanced three-dimensional suspension cell culture system and an in vitro bioreactor system to scale up the production of cultured cells and fabricate thicker vascularized tissues. In this paper, cell sheet engineering, its clinical application, and further the authors' challenge to develop innovative cell culture systems under newly legislated regulatory platform in Japan are summarized and discussed.

Vapor cycle energy system for implantable circulatory assist devices. Final summary May--Oct 1976

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watelet, R.P.; Ruggles, A.E.; Hagen, K.G.

1977-03-01

The report describes the development status of a heart assist system driven by a nuclear-fueled, electronically controlled vapor cycle engine termed the tidal regenerator engine (TRE). The TRE pressurization is controlled by a torque motor coupled to a displacer. The electrical power for the sensor, electronic logic and actuator is provided by thermoelectric modules interposed between the engine superheater and boiler. The TRE is direct-coupled to an assist blood pump which also acts as a blood-cooled heat exchanger, pressure-volume trasformer and sensor for the electronic logic. Engine cycle efficiency in excess of 14% has been demonstrated routinely. Overall system efficiencymore » on 33 watts of over 9% has been demonstrated (implied 13% engine cycle efficiency). A binary version of this engine in the annular configuration is now being tested. The preliminary tests demonstrated 10% cycle efficiency on the first buildup which ran well and started easily.« less

High temperature dynamic engine seal technology development

NASA Technical Reports Server (NTRS)

Steinetz, Bruce M.; Dellacorte, Christopher; Machinchick, Michael; Mutharasan, Rajakkannu; Du, Guang-Wu; Ko, Frank; Sirocky, Paul J.; Miller, Jeffrey H.

1992-01-01

Combined cycle ramjet/scramjet engines being designed for advanced hypersonic vehicles, including the National Aerospace Plane (NASP), require innovative high temperature dynamic seals to seal the sliding interfaces of the articulated engine panels. New seals are required that will operate hot (1200 to 2000 F), seal pressures ranging from 0 to 100 psi, remain flexible to accommodate significant sidewall distortions, and resist abrasion over the engine's operational life. This report reviews the recent high temperature durability screening assessments of a new braided rope seal concept, braided of emerging high temperature materials, that shows promise of meeting many of the seal demands of hypersonic engines. The paper presents durability data for: (1) the fundamental seal building blocks, a range of candidate ceramic fiber tows; and for (2) braided rope seal subelements scrubbed under engine simulated sliding, temperature, and preload conditions. Seal material/architecture attributes and limitations are identified through the investigations performed. The paper summarizes the current seal technology development status and presents areas in which future work will be performed.

Rapid Modeling and Analysis Tools: Evolution, Status, Needs and Directions

NASA Technical Reports Server (NTRS)

Knight, Norman F., Jr.; Stone, Thomas J.; Ransom, Jonathan B. (Technical Monitor)

2002-01-01

Advanced aerospace systems are becoming increasingly more complex, and customers are demanding lower cost, higher performance, and high reliability. Increased demands are placed on the design engineers to collaborate and integrate design needs and objectives early in the design process to minimize risks that may occur later in the design development stage. High performance systems require better understanding of system sensitivities much earlier in the design process to meet these goals. The knowledge, skills, intuition, and experience of an individual design engineer will need to be extended significantly for the next generation of aerospace system designs. Then a collaborative effort involving the designer, rapid and reliable analysis tools and virtual experts will result in advanced aerospace systems that are safe, reliable, and efficient. This paper discusses the evolution, status, needs and directions for rapid modeling and analysis tools for structural analysis. First, the evolution of computerized design and analysis tools is briefly described. Next, the status of representative design and analysis tools is described along with a brief statement on their functionality. Then technology advancements to achieve rapid modeling and analysis are identified. Finally, potential future directions including possible prototype configurations are proposed.

Advances in the Remote Monitoring of Balloon Flights

NASA Astrophysics Data System (ADS)

Breeding, S.

At the National Scientific Balloon Facility (NSBF), we must staff the Long Duration Balloon (LDB) control center 24 hours a day during LDB flights. This requires three daily shifts of two operators (balloon control and tdrss scheduling). In addition to this we also have one engineer on-call as LDB Lead to resolve technical issues and one manager on-call for flight management. These on-call periods are typically 48 to 72 hours in length. In the past the on-call staff had to travel to the LDB control center in order to monitor the status of a flight in any detail. This becomes problematic as flight durations push out beyond 20 to 30 day lengths, as these staff members are not available for business travel during these periods. This paper describes recent advances which allow for the remote monitoring of scientific balloon flight ground station computer displays. This allows balloon flight managers and lead engineers to check flight status and performance from any location with a network or telephone connection. This capability frees key personnel from the NSBF base during flights. It also allows other interested parties to check on the flight status at their convenience.

Wakata and Thirsk with MELFI in KIBO

NASA Image and Video Library

2009-06-15

ISS020-E-010028 (15 June 2009) --- Japan Aerospace Exploration Agency (JAXA) astronaut Koichi Wakata, Expedition 20 flight engineer, returns a dewar tray to the Minus Eighty Laboratory Freezer for ISS (MELFI) after inserting biological samples into the trays in the Kibo laboratory of the International Space Station. Samples were taken as part of the Nutritional Status Assessment (Nutrition) with Repository experiment, a study done by NASA to date of human physiologic changes during long-duration spaceflight. Canadian Space Agency astronaut Robert Thirsk, flight engineer, assisted Wakata.

National Wetland Plant List Indicator Rating Definitions

DTIC Science & Technology

2012-07-01

ER D C/ CR RE L TN -1 2- 1 National Wetland Plant List Indicator Rating Definitions Co ld R eg io ns R es ea rc h an d En gi ne er in... Rating Definitions Robert W. Lichvar Cold Regions Research and Engineering Laboratory U.S. Army Engineer Research and Development Center 72 Lyme...status ratings in the United States. In 2012 the list, now called the National Wetland Plant List, was updated and approved for use for various

Hurricane Barriers in New England and New Jersey - History and Status After Four Decades

DTIC Science & Technology

2007-09-01

caused by Hurricanes Katrina and Rita in September 2005, the U.S. Army Engineer District, New Orleans, of the U.S. Army Corps of Engineers (USACE...England’s 20th century history. The storm caused unprecedented damage throughout New England and Long Island, killing over 600 people and devastating...the hurricane away from the coast. Further out to sea , a Bermuda high was in place, with the result that the hurricane was squeezed between these

Configuration management plan. System definition and project development. Repository Based Software Engineering (RBSE) program

NASA Technical Reports Server (NTRS)

Mckay, Charles

1991-01-01

This is the configuration management Plan for the AdaNet Repository Based Software Engineering (RBSE) contract. This document establishes the requirements and activities needed to ensure that the products developed for the AdaNet RBSE contract are accurately identified, that proposed changes to the product are systematically evaluated and controlled, that the status of all change activity is known at all times, and that the product achieves its functional performance requirements and is accurately documented.

Genesis of a flexible turning center

NASA Astrophysics Data System (ADS)

Sanclemente, Paul; French, Robert D.

GE - Aircraft Engines has designed, built, and is operating a flexible turning center for jet engine hardware. Although the plant is in the forefront of manufacturing technology development, it was intended from the start to be a production facility. So while there was much to learn from being involved in all phases of the project, meeting production schedules was, and is, key to its success. This paper reviews the early history of the project and ends with a view of its recent production status.

HSCT noise reduction technology development at GE Aircraft Engines

NASA Technical Reports Server (NTRS)

Majjigi, Rudramuni K.

1992-01-01

The topics covered include the following: High Speed Civil Transport (HSCT) exhaust nozzle design approaches; GE aircraft engine (GEAE) HSCT acoustics research; 2DCD non-IVP suppressor ejector; key sensitivities from reference aircraft; acoustic experiments; aero-mixing experimental set-up; fluid shield nozzle; HSCT Mach 2.4 flade nozzle; noise prediction; nozzle concept for GE/Boeing joint test; scale model hot core flow path modified to prevent hub-choking CFL3-D solution; HSCT exhaust nozzle status; and key acoustic technology issues for HSCT's.

HSCT noise reduction technology development at GE Aircraft Engines

NASA Astrophysics Data System (ADS)

Majjigi, Rudramuni K.

1992-04-01

The topics covered include the following: High Speed Civil Transport (HSCT) exhaust nozzle design approaches; GE aircraft engine (GEAE) HSCT acoustics research; 2DCD non-IVP suppressor ejector; key sensitivities from reference aircraft; acoustic experiments; aero-mixing experimental set-up; fluid shield nozzle; HSCT Mach 2.4 flade nozzle; noise prediction; nozzle concept for GE/Boeing joint test; scale model hot core flow path modified to prevent hub-choking CFL3-D solution; HSCT exhaust nozzle status; and key acoustic technology issues for HSCT's.

EHV systems technology - A look at the principles and current status. [Electric and Hybrid Vehicle

NASA Technical Reports Server (NTRS)

Kurtz, D. W.; Levin, R. R.

1983-01-01

An examination of the basic principles and practices of systems engineering is undertaken in the context of their application to the component and subsystem technologies involved in electric and hybrid vehicle (EHV) development. The limitations of purely electric vehicles are contrasted with hybrid, heat engine-incorporating vehicle technology, which is inherently more versatile. A hybrid vehicle concept assessment methodology is presented which employs current technology and yet fully satisfies U.S. Department of Energy petroleum displacement goals.

Disruptive visions.

PubMed

Satava, R M

2002-10-01

Numerous advanced technologies, both medical and nonmedical, are emerging faster than their social, behavioral, political, moral, and ethical implications can be understood. Some of these technologies will fundamentally challenge the practice of surgery: human cloning, genetic engineering, tissue engineering, intelligent robotics, nanotechnology, suspended animation, regeneration, and species prolongation. Because of the rapidity of change, the current status of these emerging technologies with their specific moral and ethical issues must be addressed at this time by the new generation of surgeons, or we must all face the consequences of an uncontrolled and unprepared future.

IPCS implications for future supersonic transport aircraft

NASA Technical Reports Server (NTRS)

Billig, L. O.; Kniat, J.; Schmidt, R. D.

1976-01-01

The Integrated Propulsion Control System (IPCS) demonstrates control of an entire supersonic propulsion module - inlet, engine afterburner, and nozzle - with an HDC 601 digital computer. The program encompasses the design, build, qualification, and flight testing of control modes, software, and hardware. The flight test vehicle is an F-111E airplane. The L.H. inlet and engine will be operated under control of a digital computer mounted in the weapons bay. A general description and the current status of the IPCS program are given.

Engineering Stem Cells for Biomedical Applications

PubMed Central

Yin, Perry T.; Han, Edward

2018-01-01

Stem cells are characterized by a number of useful properties, including their ability to migrate, differentiate, and secrete a variety of therapeutic molecules such as immunomodulatory factors. As such, numerous pre-clinical and clinical studies have utilized stem cell-based therapies and demonstrated their tremendous potential for the treatment of various human diseases and disorders. Recently, efforts have focused on engineering stem cells in order to further enhance their innate abilities as well as to confer them with new functionalities, which can then be used in various biomedical applications. These engineered stem cells can take on a number of forms. For instance, engineered stem cells encompass the genetic modification of stem cells as well as the use of stem cells for gene delivery, nanoparticle loading and delivery, and even small molecule drug delivery. The present Review gives an in-depth account of the current status of engineered stem cells, including potential cell sources, the most common methods used to engineer stem cells, and the utilization of engineered stem cells in various biomedical applications, with a particular focus on tissue regeneration, the treatment of immunodeficiency diseases, and cancer. PMID:25772134

Establishing a `Centre for Engineering Experimentation and Design Simulation': a step towards restructuring engineering education in India

NASA Astrophysics Data System (ADS)

Venkateswarlu, P.

2017-07-01

Reforms in undergraduate engineering curriculum to produce engineers with entrepreneurial skills should address real-world problems relevant to industry and society with active industry support. Technology-assisted, hands-on projects involving experimentation, design simulation and prototyping will transform graduates into professionals with necessary skills to create and advance knowledge that meets global standards. To achieve this goal, this paper proposes establishing a central facility, 'Centre for Engineering Experimentation and Design Simulation' (CEEDS) in autonomous engineering colleges in India. The centre will be equipped with the most recent technology resources and computational facilities where students execute novel interdisciplinary product-oriented projects benefiting both industry and society. Students undertake two projects: a short-term project aimed at an engineering solution to a problem in energy, health and environment and the other a major industry-supported project devoted to a product that enhances innovation and creativity. The paper presents the current status, the theoretical and pedagogical foundation for the centre's relevance, an activity plan and its implementation in the centre for product-based learning with illustrative examples.

Genetic Engineering Strategies for Enhanced Biodiesel Production.

PubMed

Hegde, Krishnamoorthy; Chandra, Niharika; Sarma, Saurabh Jyoti; Brar, Satinder Kaur; Veeranki, Venkata Dasu

2015-07-01

The focus on biodiesel research has shown a tremendous growth over the last few years. Several microbial and plant sources are being explored for the sustainable biodiesel production to replace the petroleum diesel. Conventional methods of biodiesel production have several limitations related to yield and quality, which led to development of new engineering strategies to improve the biodiesel production in plants, and microorganisms. Substantial progress in utilizing algae, yeast, and Escherichia coli for the renewable production of biodiesel feedstock via genetic engineering of fatty acid metabolic pathways has been reported in the past few years. However, in most of the cases, the successful commercialization of such engineering strategies for sustainable biodiesel production is yet to be seen. This paper systematically presents the drawbacks in the conventional methods for biodiesel production and an exhaustive review on the present status of research in genetic engineering strategies for production of biodiesel in plants, and microorganisms. Further, we summarize the technical challenges need to be tackled to make genetic engineering technology economically sustainable. Finally, the need and prospects of genetic engineering technology for the sustainable biodiesel production and the recommendations for the future research are discussed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yu, Ai-Qun; Pratomo Juwono, Nina Kurniasih; Synthetic Biology Research Program, National University of Singapore, Singapore

Fatty acid derivatives, such as hydroxy fatty acids, fatty alcohols, fatty acid methyl/ethyl esters, and fatty alka(e)nes, have a wide range of industrial applications including plastics, lubricants, and fuels. Currently, these chemicals are obtained mainly through chemical synthesis, which is complex and costly, and their availability from natural biological sources is extremely limited. Metabolic engineering of microorganisms has provided a platform for effective production of these valuable biochemicals. Notably, synthetic biology-based metabolic engineering strategies have been extensively applied to refactor microorganisms for improved biochemical production. Here, we reviewed: (i) the current status of metabolic engineering of microbes that produce fattymore » acid-derived valuable chemicals, and (ii) the recent progress of synthetic biology approaches that assist metabolic engineering, such as mRNA secondary structure engineering, sensor-regulator system, regulatable expression system, ultrasensitive input/output control system, and computer science-based design of complex gene circuits. Furthermore, key challenges and strategies were discussed. Finally, we concluded that synthetic biology provides useful metabolic engineering strategies for economically viable production of fatty acid-derived valuable chemicals in engineered microbes.« less

Production of Fatty Acid-Derived Valuable Chemicals in Synthetic Microbes

PubMed Central

Yu, Ai-Qun; Pratomo Juwono, Nina Kurniasih; Leong, Susanna Su Jan; Chang, Matthew Wook

2014-01-01

Fatty acid derivatives, such as hydroxy fatty acids, fatty alcohols, fatty acid methyl/ethyl esters, and fatty alka(e)nes, have a wide range of industrial applications including plastics, lubricants, and fuels. Currently, these chemicals are obtained mainly through chemical synthesis, which is complex and costly, and their availability from natural biological sources is extremely limited. Metabolic engineering of microorganisms has provided a platform for effective production of these valuable biochemicals. Notably, synthetic biology-based metabolic engineering strategies have been extensively applied to refactor microorganisms for improved biochemical production. Here, we reviewed: (i) the current status of metabolic engineering of microbes that produce fatty acid-derived valuable chemicals, and (ii) the recent progress of synthetic biology approaches that assist metabolic engineering, such as mRNA secondary structure engineering, sensor-regulator system, regulatable expression system, ultrasensitive input/output control system, and computer science-based design of complex gene circuits. Furthermore, key challenges and strategies were discussed. Finally, we concluded that synthetic biology provides useful metabolic engineering strategies for economically viable production of fatty acid-derived valuable chemicals in engineered microbes. PMID:25566540

Research status and development of application fields in enzyme technology

NASA Astrophysics Data System (ADS)

Ji, Y. B.; Wang, S. W.; Yu, M.; Ru, X.; Wei, C.; Zhu, H. J.; Li, Z. Y.; Zhao, H.; Qiao, A. N.; Guo, S. Z.; Lu, L.

2018-01-01

Biological enzymes are catalyzed by living cells, most of which are proteins, and very few are RNA. Biological engineering as a new high-tech has been rapid development, Enzyme manufacturing and application areas are gradually expanding, In this paper, the status and progress of the application of enzyme technology are reviewed by reviewing the literature. and aims to provide reference for the application of enzyme technology and provide scientific basis for its future research and development in new field.