St. John's wort: a new alternative for depression?

PubMed

Josey, E S; Tackett, R L

1999-03-01

The primary purpose of this article is to review the existing literature concerning the therapeutic uses, adverse effects, and possible drug interactions of St. John's wort (Hypericum perforatum) as compared to other antidepressant medications. Reference material was obtained through database searches with time restrictions of 1985 to the present. Studies selected were those written in the English language which compared the role of St. John's wort, tricyclic antidepressants, monoamine oxidase inhibitors, and serotonin-selective reuptake inhibitors in the treatment of depression. Other studies were selected based on their evaluation of the safety and efficacy of St. John's wort as an antidepressant for a minimum of four weeks. A review of existing literature recognized nine clinical trials that reported the efficacy of St. John's wort as compared to placebo and to other antidepressant medications. Of these nine, four controlled studies were chosen based upon their large patient populations and their consistency in brand and dosage of St. John's wort used. These four studies demonstrated that St. John's wort was as effective as other antidepressant medications and more effective than placebo, as the clinical symptoms of depression greatly decreased upon administration of H. perforatum. The side-effect profile of H. perforatum at this time appears to be superior to any current U.S.-approved antidepressant medication. From the existing literature, St. John's wort appears to be a safe and effective alternative in the treatment of depression. Tricylic antidepressants and monoamine oxidase inhibitors can produce serious cardiac side-effects, such as tachycardia and postural hypotension, and many unwanted anticholinergic side-effects, including dry mouth and constipation. St. John's wort has proven to be free of any cardiac, as well as anticholinergic, side-effects normally seen with antidepressant medications. Based upon limited studies, St. John's wort appears to be an acceptable alternative to traditional antidepressant therapy, although trials on a larger scale are warranted in this area. Hypericum is available to the lay public as an over-the-counter preparation and may be misused if not fully understood.

33 CFR 117.325 - St. Johns River.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false St. Johns River. 117.325 Section 117.325 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Florida § 117.325 St. Johns River. (a) The drawspan...

40 CFR 81.356 - Virgin Islands.

Code of Federal Regulations, 2011 CFR

2011-07-01

... St. John St. Thomas 1 This date is November 15, 1990, unless otherwise noted. Virgin Islands—Ozone (1... Unclassifiable/Attainment St. Croix St. John St. Thomas 1 This date is October 18, 2000, unless otherwise noted... St. Thomas 1 This date is June 15, 2004, unless otherwise noted. Virgin Islands—PM2.5 (Annual NAAQS...

33 CFR 110.73 - St. Johns River, Fla.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false St. Johns River, Fla. 110.73 Section 110.73 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73 St. Johns River, Fla. (a) Area A. The waters lying...

33 CFR 110.73 - St. Johns River, Fla.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false St. Johns River, Fla. 110.73 Section 110.73 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73 St. Johns River, Fla. (a) Area A. The waters lying...

33 CFR 110.73 - St. Johns River, Fla.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false St. Johns River, Fla. 110.73 Section 110.73 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73 St. Johns River, Fla. (a) Area A. The waters lying...

33 CFR 110.73 - St. Johns River, Fla.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false St. Johns River, Fla. 110.73 Section 110.73 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.73 St. Johns River, Fla. (a) Area A. The waters lying...

Chemistry of St. John's Wort: Hypericin and Hyperforin

ERIC Educational Resources Information Center

Vollmer, John J.; Rosenson, Jon

2004-01-01

The appeal as natural antidepressant is the major selling point of St. John's Wort, which is referred to as "Prozac from the plant kingdom". Hypericin and hyperforin, two major constituents with significant biological activity of St. John's Wort and which are complex molecules with unusual features, are examined.

Understanding drug interactions with St John's wort (Hypericum perforatum L.): impact of hyperforin content.

PubMed

Chrubasik-Hausmann, Sigrun; Vlachojannis, Julia; McLachlan, Andrew J

2018-02-07

The aim of this study was to review herb-drug interaction studies with St John's wort (Hypericum perforatum L.) with a focus on the hyperforin content of the extracts used in these studies. PUBMED was systematically searched to identify studies describing pharmacokinetic interactions involving St John's wort. Data on study design and the St John's wort extract or product were gathered to extract hyperforin content and daily dose used in interaction studies. This analysis demonstrates that significant herb-drug interactions (resulting in a substantial change in systemic exposure) with St John's wort products were associated with hyperforin daily dosage. Products that had a daily dose of <1 mg hyperforin were less likely to be associated with major interaction for drugs that were CYP3A4 or p-glycoprotein substrates. Although a risk of interactions cannot be excluded even for low-dose hyperforin St. John's wort extracts, the use of products that result in a dose of not more than 1 mg hyperforin per day is recommended to minimise the risk of interactions. This review highlights that the significance of herb-drug interactions with St John's wort is influenced by the nature of the herbal medicines product, particularly the hyperforin content. © 2018 Royal Pharmaceutical Society.

Using Scholarship Management Research to Optimize the Impact of Scholarship Funds

ERIC Educational Resources Information Center

James, Glenn W.; Mahajan, Shubhada S.

2004-01-01

Scholarship aid continues to be crucially important in attracting and retaining students in higher education institutions (Abrahamson & Hossler, 1990; Cabrera, Nora, & Castaneda, 1992; Paulsen & St. John, 1997; Schuh, 2000; St. John, 1992; St. John et al., 1994; Terkla, 1985). Although the general concept and effect of financial assistance is…

33 CFR 334.500 - St. Johns River, Atlantic Ocean, Sherman Creek; restricted areas and danger zone, Naval Station...

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false St. Johns River, Atlantic Ocean... AND RESTRICTED AREA REGULATIONS § 334.500 St. Johns River, Atlantic Ocean, Sherman Creek; restricted... area and the Atlantic Ocean restricted area described in paragraphs (a)(2) and (a)(3) of this section...

33 CFR 334.500 - St. Johns River, Atlantic Ocean, Sherman Creek; restricted areas and danger zone, Naval Station...

Code of Federal Regulations, 2012 CFR

2012-07-01

... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false St. Johns River, Atlantic Ocean... AND RESTRICTED AREA REGULATIONS § 334.500 St. Johns River, Atlantic Ocean, Sherman Creek; restricted... area and the Atlantic Ocean restricted area described in paragraphs (a)(2) and (a)(3) of this section...

33 CFR 334.500 - St. Johns River, Atlantic Ocean, Sherman Creek; restricted areas and danger zone, Naval Station...

Code of Federal Regulations, 2013 CFR

2013-07-01

... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false St. Johns River, Atlantic Ocean... AND RESTRICTED AREA REGULATIONS § 334.500 St. Johns River, Atlantic Ocean, Sherman Creek; restricted... area and the Atlantic Ocean restricted area described in paragraphs (a)(2) and (a)(3) of this section...

33 CFR 334.510 - U.S. Navy Fuel Depot Pier, St. Johns River, Jacksonville, Fla.; restricted area.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false U.S. Navy Fuel Depot Pier, St. Johns River, Jacksonville, Fla.; restricted area. 334.510 Section 334.510 Navigation and Navigable... REGULATIONS § 334.510 U.S. Navy Fuel Depot Pier, St. Johns River, Jacksonville, Fla.; restricted area. (a) The...

78 FR 34042 - Fisheries of the Caribbean, Gulf of Mexico, and South Atlantic; Comprehensive Fishery Management...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-06

... Exclusive Economic Zone of St. Thomas/St. John AGENCY: National Marine Fisheries Service (NMFS), National... economic zone (EEZ) of St. Thomas/St. John. The purpose of this NOI is to inform the public of upcoming..., NMFS, 263 13th Avenue South, St. Petersburg, FL 33701, or to the Caribbean Fishery Management Council...

Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis.

PubMed

Ng, Qin Xiang; Venkatanarayanan, Nandini; Ho, Collin Yih Xian

2017-03-01

St John's wort is a popular herbal remedy recommended by Traditional Chinese Medicine (TCM) practitioners and licensed and widely prescribed for depression in many European countries. However, conflicting data regarding its benefits and risks exist, and the last large meta-analysis on St John's wort use for depression was done in 2008, with no updated meta-analysis available. Using the keywords [St John's Wort OR Hypericum perforatum OR hypericin OR hyperforin OR johanniskraut OR] AND [depression OR antidepressant OR SSRI], a preliminary search (without language restriction) on the PubMed, Ovid, Clinical Trials Register of the Cochrane Collaboration Depression, Anxiety and Neurosis Group, Cochrane Field for Complementary Medicine, China National Knowledge Infrastructure and WanFang database yielded 5428 papers between 1-Jan-1960 and 1-May-2016. 27 clinical trials with a total of 3808 patients were reviewed, comparing the use of St John's wort and SSRI. In patients with depression, St John's wort demonstrated comparable response (pooled RR 0.983, 95% CI 0.924-1.042, p<0.001) and remission (pooled RR 1.013, 95% CI 0.892-1.134, p<0.001) rate, and significantly lower discontinuation/dropout (pooled OR 0.587, 95% CI 0.478-0.697, p<0.001) rate compared to standard SSRIs. The pooled SMD from baseline HAM-D scores (pooled SMD -0.068, 95% CI -0.127 to 0.021, p<0.001) also support its significant clinical efficacy in ameliorating depressive symptoms. Evidence on the long-term efficacy and safety of St. John's wort is limited as the duration of all available studies ranged from 4 to 12 weeks. It is also unclear if St John's wort would be beneficial for patients with severe depression, high suicidality or suicide risk. For patients with mild-to-moderate depression, St John's wort has comparable efficacy and safety when compared to SSRIs. Follow-up studies carried out over a longer duration should be planned to ascertain its benefits. Copyright © 2017 Elsevier B.V. All rights reserved.

Effect of St.John's wort (Hypericum perforatum) oily extract for the care and treatment of pressure sores; a case report.

PubMed

Yücel, Ali; Kan, Yüksel; Yesilada, Erdem; Akın, Onat

2017-01-20

Topical formulations such as oily extracts or ointments prepared with the flowering aerial parts of St. John's wort (Hypericum perforatum L., Hypericaceae) have been used in the management of a wide range dermatological problems including superficial wounds and burns, bruises, contusions and many others in the worldwide traditional medicines. This is the first case study reporting the beneficial effects of an oily extract of St. John's wort in the treatment of pressure sores in a intensive care unit (ICU) patient. The oily extract of St. John's wort was applied to a volunteer patient at ICU daily for forty successive days for wound care and treatment. Healing status was monitored macroscopically by measuring the wound size and stages at certain intervals as well as histopathological evaluation of the tissue sections taken at the initial and final dates of treatment. Evaluation of the results obtained from the macroscopical and histopathological experimentation have shown that oily extract of St. John's wort provided significant efficacy for the treatment of pressure sore wounds. St. John's wort oily extract may be suggested as a cost-effective option for the prevention or treatment of pressure sores in ICU patients. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Coastal Sediment Distribution Patterns Following Category 5 Hurricanes (Irma and Maria): Pre and Post Hurricane High Resolution Multibeam Surveys of Eastern St. John, US Virgin Islands

NASA Astrophysics Data System (ADS)

Browning, T. N.; Sawyer, D. E.; Russell, P.

2017-12-01

In August of 2017 we collected high resolution multibeam data of the seafloor in a large embayment in eastern St. John, US Virgin Islands (USVI). One month later, the eyewall of Category 5 Hurricane Irma directly hit St. John as one of the largest hurricanes on record in the Atlantic Ocean. A week later, Category 5 Hurricane Maria passed over St. John. While the full extent of the impacts are still being assessed, the island experienced a severe loss of vegetation, infrastructure, buildings, roads, and boats. We mobilized less than two months afterward to conduct a repeat survey of the same area on St. John. We then compared these data to document and quantify the sediment influx and movement that occurred in coastal embayments as a result of Hurricanes Irma and Maria. The preliminary result of the intense rain, wind, and storm surge likely yields an event deposit that can be mapped and volumetrically quantified in the bays of eastern St. John. The results of this study allow for a detailed understanding of the post-hurricane pulse of sediment that enters the marine environment, the sediment flux seaward, and the morphological changes to the bay floor.

Geology of St. John, U.S. Virgin Islands

USGS Publications Warehouse

Rankin, Douglas W.

2002-01-01

The rocks of St. John, which is located near the eastern end of the Greater Antilles and near the northeastern corner of the Caribbean plate, consist of Cretaceous basalt, andesite, keratophyre, their volcaniclastic and hypabyssal intrusive equivalents, and minor calcareous rocks and chert. These rocks were intruded by Tertiary mafic dikes and tonalitic plutons. The oldest rocks formed in an extensional oceanic environment characterized by abundant keratophyre and sheeted dikes. Subduction-related volcanism of the east-west-trending marine Greater Antilles volcanic arc began on St. John near the transition between the Early and Late Cretaceous. South-directed compression, probably caused by the initial collision between the Greater Antilles arc of the Caribbean plate and the Bahama platform of the North American plate, deformed the Cretaceous strata into east-west-trending folds with axial-plane cleavage. Late Eocene tonalitic intrusions, part of the Greater Antilles arc magmatism, produced a contact aureole that is as much as two kilometers wide and that partly annealed the axial-plane cleavage. East-west compression, possibly related to the relative eastward transport of the Caribbean plate in response to the beginning of spreading at the Cayman Trough, produced long-wavelength, low-amplitude folds whose axes plunge gently north and warp the earlier folds. A broad north-plunging syncline-anticline pair occupies most of St. John. The last tectonic event affecting St. John is recorded by a series of post-late Eocene sinistral strike-slip faults related to the early stages of spreading at the Cayman Trough spreading center and sinistral strike-slip accommodation near the northern border of the Caribbean plate. Central St. John is occupied by a rhomb horst bounded by two of these sinistral faults. Unlike other parts of the Greater Antilles, evidence for recent tectonic movement has not been observed on St. John.

Chemistry of St. John's Wort: Hypericin and Hyperforin

NASA Astrophysics Data System (ADS)

Vollmer, John J.; Rosenson, Jon

2004-10-01

St. John's wort is a common plant that has been used medicinally for over 20 centuries. This herb is currently used by millions of people, primarily as natural antidepressant; yet, its efficacy is still under constant debate. St. John's wort contains a large aromatic molecule, hypericin, twisted by steric interactions into the shape of a propeller. For use as antidepressant, St. John's wort is standardized to the content of hypericin, but this molecule was recently found not to be the active ingredient. A totally different bicyclic molecule with complex substitution pattern, hyperforin, was then studied as the causative agent. Both molecules are strongly active in biological systems. Hypericin has shown antiviral activity and is a potent natural photosensitizer that has been used in photodynamic therapy against cancer and against HIV in stored blood. Hyperforin was found to activate a particular receptor in the liver that induces the production of an enzyme used for the metabolism of medications. This effect causes more rapid breakdown of many prescription medications and can interfere with their effectiveness. This finding should prompt a reevaluation of regular use of St. John's wort.

St. John Health integrating new corporate identity, brand. Brand/logo to be rolled out over two-year period.

PubMed

Rees, Tom

2003-01-01

St. John Health, Warren, Mich., is integrating a new corporate identity and brand strategy for its network of nine wholly-owned and two affiliated hospital, along with more than 100 physician offices and specialty centers in southeast Michigan. "A new identity is a great rallying cry. It automatically says. 'We have a new mission. We have a new system. We are reaching new people,'" said Eunice O'Loughlan, VP, corporate communications for St. John Health.

40 CFR 81.53 - Southern Louisiana-Southeast Texas Interstate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Parish, St. Bernard Parish, St. Charles Parish, St. Helena Parish, St. James Parish, St. John the Baptist Parish, St. Landry Parish, St. Martin Parish, St. Mary Parish, St. Tammany Parish, Tangipahoa Parish...

Estimated discharge and chemical-constituent loading from the upper Floridan aquifer to the lower St John's River, northeastern Florida, 1990-91

USGS Publications Warehouse

Spechler, R.M.

1995-01-01

The lower St. Johns River, a 101-mile long segment of the St. Johns River, begins at the confluence of the Ocklawaha River and ends where the river discharges into the Atlantic Ocean at Mayport. The St. Johns River is affected by tides as far upstream as Lake George, 106 miles from the mouth. Saltwater from the ocean advances inland during each incoming tide and recedes during each outgoing tide. The chemical quality of the lower St. Johns River is highly variable primarily because of the inflow of saltwater from the ocean, and in some areas, from the discharge of mineralized ground water. Three hydrogeologic units are present in the study area: the surficial aquifer system, the intermediate confining unit, and the Floridan aquifer system. The surficial aquifer system overlies the intermediate confining unit and consists of deposits containing sand, clay, shell, and some limestone and dolomite. The intermediate confining unit underlies all of the study area and retards the vertical movement of water between the surficial aquifer system and the Floridan aquifer system. The intermediate confining unit consists of beds of relatively low permeability sediments that vary in thickness and areal extent and can be breached by sinkholes, fractures, and other openings. The Floridan aquifer system primarily consists of limestone and dolomite. The quality of water in the Upper Floridan aquifer varies throughout the study area. Dissolved solids in water range from about 100 to more than 5,000 milligrams per liter. Chloride and sulfate concentrations in water from the Upper Floridan aquifer range from about 4 to 3,700 milligrams per liter and from 1 to 1,300 milligrams per liter, respectively. The rate of leakage through the intermediate confining unit is controlled by the leakance coefficient of the intermediate confining unit and by the head difference between the Upper Floridan aquifer and the surficial aquifer system. The total ground-water discharge from the Upper Floridan aquifer to the St. Johns River within the lower St. Johns River drainage basin, based on the potentiometric surface of the Upper Floridan aquifer in September 1990, was estimated to be 86 cubic feet per second. Total estimated ground-water discharge to the lower St. Johns River in September 1991, when heads in the Upper Floridan aquifer averaged about 4 feet higher than in 1990, was 133 cubic feet per second. The load of dissolved-solids that discharged from the Upper Floridan aquifer into the lower St. Johns River on the basis of September 1990 heads is estimated to be 47,000 tons per year. Estimated chloride and sulfate loads are 18,000 and 9,500 tons per year, respectively. Dissolved-solids, chloride, and sulfate loads discharging into the lower St. Johns River are estimated to be 81,000, 39,000, and 15,000 tons per year, respectively, on the basis of September 1991 heads.

An in vitro and hydroponic growing system for hypericin, pseudohypericin, and hyperforin production of St. John's wort (Hypericum perforatum CV new stem).

PubMed

Murch, Susan J; Rupasinghe, H P Vasantha; Saxena, Praveen K

2002-12-01

While the interest in medicinal plants continues to grow, there is a lack of basic information with respect to efficient protocols for plant production. Recently, in vitro regeneration protocols have been developed to provide masses of sterile, consistent St. John's wort. The current study assessed the potential for acclimatization of in vitro grown St. John's wort plantlets to a nutrient film technique (NFT) hydroponic system in a controlled environment greenhouse. Quantitative analyses of hypericin, hyperforin and pseudohypericin in flower tissues were used as the parameters to assess the quality of the greenhouse-grown plants. The three bioactive compounds were found to be present in similar or higher amounts than previously reported values for field-grown plants. These data provide evidence that greenhouse hydroponic systems can be effectively used for the efficient production of St. John's wort and other medicinal plants.

50 CFR 17.108 - List of designated manatee protection areas.

Code of Federal Regulations, 2011 CFR

2011-10-01

... bank of the Trout River and the left descending bank of the St. Johns River) and Reddie Point, as...)(vi) of this section. (ii) In the St. Johns River from Sandfly Point on the left descending bank of... slow speed, year-round, within 300 feet (91 m) of the shoreline on the left descending bank of the St...

The effects of St. John's wort extract and amitriptyline on autonomic responses of blood vessels and sweat glands in healthy volunteers.

PubMed

Siepmann, Martin; Kirch, Wilhelm; Krause, Stephanie; Joraschky, Peter; Mueck-Weymann, Michael

2004-02-01

St. John's wort extract is widely used and advertised as a "natural antidepressant" lacking autonomic side effects. This randomized, double-blind, placebo-controlled study compared the effects of St. John's wort extract on autonomic responses of blood vessels and sweat glands with those of amitriptyline and placebo. A randomized, double-blind, crossover study was performed in healthy male volunteers aged 22 to 31 years (25 +/- 3 years; mean +/- SD) years. Subjects orally received capsules with 255 to 285 mg St. John's wort extract (900 microg hypericin content), 25 mg amitriptyline, and placebo 3 times daily for periods of 14 days each with at least 14 days between. Vasoconstrictory response of cutaneous blood flow (VR) and skin conductance response (SR) following a single deep inspiration were employed as parameters of autonomic function. St. John's wort extract had no effect on VR and SR. In contrast, SR was diminished and the dilation phase of VR was prolonged following multiple dosing with amitriptyline (P < 0.05). Decreased electrodermal reactivity observed with amitriptyline reflects inhibition of acetylcholine at peripheral m3-cholinoreceptors, whereas prolongation of VR induced by the tricyclic drug may be due to sustained activation of central and/or peripheral sympathetic neurons.

A CFO's Perspective on the Quality Revolution.

ERIC Educational Resources Information Center

Norton, Alan J.

1994-01-01

The chief financial officer (CFO) of St. John Fisher College (New York) analyzes the costs associated with the implementation of quality management at St. John Fisher and outlines one way to determine whether the investment is yielding an acceptable internal rate of return. (DB)

International Program and Local Organizing Committees

NASA Astrophysics Data System (ADS)

2012-12-01

International Program Committee Dionisio Bermejo (Spain) Roman Ciurylo (Poland) Elisabeth Dalimier (France) Alexander Devdariani (Russia) Milan S Dimitrijevic (Serbia) Robert Gamache (USA) Marco A Gigosos (Spain) Motoshi Goto (Japan) Magnus Gustafsson (Sweden) Jean-Michel Hartmann (France) Carlos Iglesias (USA) John Kielkopf (USA) John C Lewis (Canada) Valery Lisitsa (Russia) Eugene Oks (USA) Christian G Parigger (USA) Gillian Peach (UK) Adriana Predoi-Cross (Canada) Roland Stamm (Germany) Local Organizing Committee Nikolay G Skvortsov (Chair, St Petersburg State University) Evgenii B Aleksandrov (Ioffe Physico-Technical Institute, St Petersburg) Vadim A Alekseev (Scientific Secretary, St Petersburg State University) Sergey F Boureiko (St.Petersburg State University) Yury N Gnedin (Pulkovo Observatory, St Petersburg) Alexander Z Devdariani (Deputy Chair, St Petersburg State University) Alexander P Kouzov (Deputy Chair, St Petersburg State University) Nikolay A Timofeev (St Petersburg State University)

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

PubMed Central

Moore, Linda B.; Goodwin, Bryan; Jones, Stacey A.; Wisely, G. Bruce; Serabjit-Singh, Cosette J.; Willson, Timothy M.; Collins, Jon L.; Kliewer, Steven A.

2000-01-01

St. John's wort (Hypericum perforatum) is an herbal remedy used widely for the treatment of depression. Recent clinical studies demonstrate that hypericum extracts increase the metabolism of various drugs, including combined oral contraceptives, cyclosporin, and indinavir. In this report, we show that hyperforin, a constituent of St. John's wort with antidepressant activity, is a potent ligand (Ki = 27 nM) for the pregnane X receptor, an orphan nuclear receptor that regulates expression of the cytochrome P450 (CYP) 3A4 monooxygenase. Treatment of primary human hepatocytes with hypericum extracts or hyperforin results in a marked induction of CYP3A4 expression. Because CYP3A4 is involved in the oxidative metabolism of >50% of all drugs, our findings provide a molecular mechanism for the interaction of St. John's wort with drugs and suggest that hypericum extracts are likely to interact with many more drugs than previously had been realized. PMID:10852961

6. John N. Vogel, Photographer, June 2000 View to east. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. John N. Vogel, Photographer, June 2000 View to east. Center pier. Sabin and Davis Locks to left (north). New Poe and MAcArthur Locks to right (south) - St. Mary's Falls Canal, Soo Locks, St. Mary's River at Falls, Sault Ste. Marie, Chippewa County, MI

Hyperforin, the active component of St. John's wort, induces IL-8 expression in human intestinal epithelial cells via a MAPK-dependent, NF-kappaB-independent pathway.

PubMed

Zhou, Changcheng; Tabb, Michelle M; Sadatrafiei, Asal; Grün, Felix; Sun, Aixu; Blumberg, Bruce

2004-11-01

St. John's wort is widely used as an herbal antidepressant and is among the top-selling botanical products in the United States. Although St. John's wort has been reported to have minimal side effects compared with other antidepressants, here we show that hyperforin, the active component of St. John's wort, can stimulate interleukin-8 (IL-8) expression in human intestinal epithelia cells (IEC) and primary hepatocytes. Hyperforin is also able to induce expression of mRNA, encoding another major inflammatory mediator--intercellular adhesion molecule-1 (ICAM-1). IEC participate in the intestinal inflammatory process and serve as a first line of defense through bidirectional communication between host and infectious pathogens. Although hyperforin is a potent ligand for the steroid and xenobiotic receptor (SXR), we found that hyperforin induced IL-8 mRNA through an SXR-independent transcriptional activation pathway. IL-8 induction by hyperforin required the activation of AP-1 but not the NF-kappaB transcription factor, thereby distinguishing it from the NF-kappaB-dependent IL-8 induction mediated by tumor necrosis factor alpha (TNFalpha). Further study revealed that extracellular signal-regulated kinase 1 and 2 (ERK1/2) were required for the hyperforin-induced expression of IL-8. Our results suggest a previously unsuspected effect of St. John's wort in modulating the immune and inflammatory responses.

7 CFR 905.16 - Regulation Area II.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Regulation Area II. 905.16 Section 905.16 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... the St. Johns River; thence along the main channel of the St. Johns River and through Lake Harney...

Food and Food Constituents, Acute Effects on Human Behavior

DTIC Science & Technology

2002-12-01

include the following: individual amino acids; herbal products such as ginkgo biloba, St. John’s wort, kava kava and ginseng; weight loss products, which...for example, melatonin, ginkgo biloba, ephedrine, St. John’s won, and kava kava. Many of these naturally occurring products would be classified as drugs

78 FR 38829 - Special Local Regulations; Recurring Marine Events in the Seventh Coast Guard District

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-28

... regulation for the St. John 4th of July Carnival Fireworks Display from 8 p.m. until 10 p.m. on July 4, 2013...: The Coast Guard will enforce the special local regulation for the annual St. John 4th of July Carnival...

5 CFR 591.215 - Where does OPM collect prices in the COLA and DC areas?

Code of Federal Regulations, 2011 CFR

2011-01-01

.... Virgin Islands also has two survey areas: the Island of St. Croix and the Islands of St. Thomas and St.../Caguas area. 2 U.S. Virgin Islands St. Croix. St. Thomas/St. John area. 3 Washington, DC-DC District of...

Streamflow and water-quality characteristics at selected sites of the St. Johns River in central Florida, 1933 to 2002

USGS Publications Warehouse

Kroening, Sharon E.

2004-01-01

To meet water-supply needs in central Florida for 2020, the St. Johns River is being considered as a source of water supply to augment ground water from the Floridan aquifer system. Current (2004) information on streamflow and water-quality characteristics of the St. Johns River in east-central Florida is needed by water resources planners to assess the feasibility of using the river as an alternate source of water supply and to design water treatment facilities. To address this need, streamflow and water quality of the 90-mile-long middle reach of the St. Johns River, Florida, from downstream of Lake Poinsett to near DeLand, were characterized by using retrospective (1991-99) and recently collected data (2000-02). Streamflow characteristics were determined by using data from water years 1933-2000. Water-quality characteristics were described using data from 1991-99 at 15 sites on the St. Johns River and 1 site each near the mouths of the Econlockhatchee and Wekiva Rivers. Data were augmented with biweekly water-quality data and continuous physical properties data at four St. Johns River sites and quarterly data from sites on the Wekiva River, Blackwater Creek, and downstream of Blue Springs from 2000-02. Water-quality constituents described were limited to information on physical properties, major ions and other inorganic constituents, nutrients, organic carbon, suspended solids, and phytoplankton chlorophyll-a. The occurrence of antibiotics, human prescription and nonprescription drugs, pesticides, and a suite of organic constituents, which may indicate domestic or industrial waste, were described at two St. Johns River sites using limited data collected in water years 2002-03. The occurrence of these same constituents in water from a pilot water treatment facility on Lake Monroe also was described using data from one sampling event conducted in March 2003. Dissolved oxygen concentration and water pH values in the St. Johns River were significantly lower during high-flow conditions than during low-flow conditions. Low dissolved oxygen concentrations may have resulted from the input of water from marsh areas or the subsequent decomposition of organic matter transported to the river during high-flow events. Low water pH values during high-flow conditions likely resulted from the increased dissolved organic carbon concentrations in the river. Concentrations of total dissolved solids and other inorganic constituents in the St. Johns River were inversely related with streamflow. Most major ion concentrations, total dissolved solids concentrations, and specific conductance values varied substantially at the Christmas, Sanford, and DeLand sites during low-flow periods in 2000-01 probably reflecting wind and tidal effects. Sulfide concentrations as high as 6 milligrams per liter (mg/L) were measured in the St. Johns River during high-flow periods. Increased sulfide concentrations likely resulted from the decomposition of organic matter or the reduction of sulfate. Bromide concentrations as high as 17 mg/L were measured at the most upstream site on the St. Johns River during 2000-02. Temporal variations in bromide were characterized by sharp peaks in concentration during low-flow periods. Peaks in bromide concentrations tended to coincide with peaks in chloride concentrations because the likely source of both constituents is ground water affected by relict seawater. Median dissolved organic carbon concentrations ranged from 15 to 26 mg/L during 2000-02, and concentrations as high as 42 mg/L were measured. Water color values and dissolved organic carbon concentrations generally were significantly greater during high-flow conditions than during low-flow conditions. Specific ultraviolet light absorbance data indicated the organic carbon during high-flow events was more aromatic in composition and likely originated from terrestrially derived sources compared to organic carbon in the river during other times of the year. D

A comparative analysis of resistance testing methods in Aedes albopictus (Diptera: Culicidae) from St. Johns County, Florida

USDA-ARS?s Scientific Manuscript database

Aedes albopictus Skuse (Diptera: Culicidae) was tested for resistance to permethrin, bifenthrin, and malathion using Centers for Disease Control and Prevention (CDC) bottle bioassays and topical toxicology assays on adults and larval bioassays. Eggs were collected from 3 locations across St. Johns C...

Characterization of shallow groundwater quality in the Lower St. Johns River Basin: a case study

Treesearch

Ying Ouyang; Jia-En Zhang; Prem Parajuli

2013-01-01

Characterization of groundwater quality allows the evaluation of groundwater pollution and provides information for better management of groundwater resources. This study characterized the shallow groundwater quality and its spatial and seasonal variations in the Lower St. Johns River Basin, Florida, USA, under agricultural, forest, wastewater, and residential land...

33 CFR 165.720 - Safety/Security Zone: St. Johns River, Jacksonville, FL.

Code of Federal Regulations, 2014 CFR

2014-07-01

... vessel during its transit of the St. Johns River and out to three (3) nautical miles offshore. (b...: (1) All waters within 200 yards of Blount Island, Jacksonville, Florida and all adjacent land within 100 yards of the island shoreline during staging of Department of Defense equipment and during the...

33 CFR 165.720 - Safety/Security Zone: St. Johns River, Jacksonville, FL.

Code of Federal Regulations, 2011 CFR

2011-07-01

... vessel during its transit of the St. Johns River and out to three (3) nautical miles offshore. (b...: (1) All waters within 200 yards of Blount Island, Jacksonville, Florida and all adjacent land within 100 yards of the island shoreline during staging of Department of Defense equipment and during the...

33 CFR 165.720 - Safety/Security Zone: St. Johns River, Jacksonville, FL.

Code of Federal Regulations, 2012 CFR

2012-07-01

... vessel during its transit of the St. Johns River and out to three (3) nautical miles offshore. (b...: (1) All waters within 200 yards of Blount Island, Jacksonville, Florida and all adjacent land within 100 yards of the island shoreline during staging of Department of Defense equipment and during the...

33 CFR 165.720 - Safety/Security Zone: St. Johns River, Jacksonville, FL.

Code of Federal Regulations, 2013 CFR

2013-07-01

... vessel during its transit of the St. Johns River and out to three (3) nautical miles offshore. (b...: (1) All waters within 200 yards of Blount Island, Jacksonville, Florida and all adjacent land within 100 yards of the island shoreline during staging of Department of Defense equipment and during the...

NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's Wort.

PubMed

Kumar, Vikas; Mdzinarishvili, Alexander; Kiewert, Cornelia; Abbruscato, Thomas; Bickel, Ulrich; van der Schyf, Cornelis J; Klein, Jochen

2006-09-01

Extracts of the medicinal plant St. John's wort (Hypericum perforatum) are widely used for the treatment of affective disorders. Hyperforin, a constituent of St. John's wort, is known to modulate the release and re-uptake of various neurotransmitters, an action that likely underlies its antidepressive activity. We now report that hyperforin also has N-methyl-D-aspartate (NMDA)-antagonistic effects. Hyperforin (10 microM) was found to inhibit the NMDA-induced calcium influx into cortical neurons. In rat hippocampal slices, hyperforin inhibited the NMDA-receptor-mediated release of choline from phospholipids. Hyperforin also antagonized the increase of water content in freshly isolated hippocampal slices, and it counteracted, at 3 and 10 microM, the increase of water content induced by NMDA. Hyperforin was inactive, however, in two in vivo models of brain edema formation, middle cerebral artery occlusion and water intoxication in mice. In conclusion, hyperforin has NMDA-receptor-antagonistic and potential neuroprotective effects in vitro. This effect may contribute to the therapeutic effectiveness of St. John's wort extracts in some situations, for example, for relapse prevention in alcoholism.

Assessing the continuity of the upland sediment cascade, fluvial geomorphic response of an upland river to an extreme flood event: Storm Desmond, Cumbria, UK.

NASA Astrophysics Data System (ADS)

Joyce, Hannah; Hardy, Richard; Warburton, Jeff

2017-04-01

Hillslope erosion and accelerated lake sedimentation are often viewed as the source and main storage elements in the upland sediment cascade. However, the continuity of sediment transfer through intervening valley systems has rarely been evaluated during extreme events. Storm Desmond (4th - 6th December, 2015) produced record-breaking rainfall maximums in the UK: 341.4 mm rainfall was recorded in a 24 hour period at Honister Pass, Western Lake District, and 405 mm of rainfall was recorded in a 38 hour period at Thirlmere, central Lake District. The storm was the largest in a 150 year local rainfall series, and exceeded previous new records set in the 2005 and 2009 floods. During this exceptional event, rivers over topped flood defences, and caused damage to over 257 bridges, flooded over 5000 homes and businesses, and caused substantial geomorphic change along upland rivers. This research quantifies the geomorphic and sedimentary response to Storm Desmond along a regulated gravel-bed river: St John's Beck. St John's Beck (length 7.8 km) is a channelised low gradient river (0.005) downstream of Thirlmere Reservoir, which joins the River Greta, and flows through Keswick, where major flooding has occurred, before discharging into Bassenthwaite Lake. St John's Beck has a history of chronic sediment aggradation, erosion and reports of historic flooding date back to 1750. During Storm Desmond, riverbanks were eroded, coarse sediment was deposited across valuable farmland and access routes were destroyed, including a bridge and footpaths, disrupting local business. A sediment budget framework has been used to quantify geomorphic change and sedimentary characteristics of the event along St John's Beck. The volume and sediment size distribution of flood deposits, channel bars, tributary deposits, floodplain scour, riverbank erosion and in-channel bars were measured directly in the field and converted to mass using local estimates of coarse and fine sediment bulk densities. During the event 5000 tonnes of sediment was deposited on floodplains surrounding St John's Beck; 65% of this sediment was deposited in the first 3 km of the reach downstream of Thirlmere Reservoir where the channel is unconfined and channel slope and capacity rapidly decrease. Flood sediment deposits were composed of a single layer of sediment of a similar grain size distribution (mean D90 116 mm), with fines generally sparse. The main source of sediment deposited during the event originated from the channel bed and banks; 1500 tonnes of sediment was stored within channel bars. Approximately 2000 tonnes of sediment was eroded from the riverbanks during the event; with local lateral riverbank recession exceeding 12 m. An estimated 500 tonnes of sediment was scoured from the floodplains along the first 3 km of the reach downstream of Thirlmere Reservoir, with local floodplain scour around a bridge estimated at 300 tonnes. Overall, this sediment budget study demonstrates the importance of valley systems as a major source and sink of sediment along the upland sediment cascade during an extreme flood event.

St. John's wort significantly increased the systemic exposure and toxicity of methotrexate in rats

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, Shih-Ying; Juang, Shin-Hun; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan

2012-08-15

St. John's wort (SJW, Hypericum perforatum) is one of the popular nutraceuticals for treating depression. Methotrexate (MTX) is an immunosuppressant with narrow therapeutic window. This study investigated the effect of SJW on MTX pharmacokinetics in rats. Rats were orally given MTX alone and coadministered with 300 and 150 mg/kg of SJW, and 25 mg/kg of diclofenac, respectively. Blood was withdrawn at specific time points and serum MTX concentrations were assayed by a specific monoclonal fluorescence polarization immunoassay method. The results showed that 300 mg/kg of SJW significantly increased the AUC{sub 0−t} and C{sub max} of MTX by 163% and 60%,more » respectively, and 150 mg/kg of SJW significantly increased the AUC{sub 0−t} of MTX by 55%. In addition, diclofenac enhanced the C{sub max} of MTX by 110%. The mortality of rats treated with SJW was higher than that of controls. In conclusion, coadministration of SJW significantly increased the systemic exposure and toxicity of MTX. The combined use of MTX with SJW would need to be with caution. -- Highlights: ► St. John's wort significantly increased the AUC{sub 0−t} and C{sub max} of methotrexate. ► Coadministration of St. John's wort increased the exposure and toxicity of methotrexate. ► The combined use of methotrexate with St. John's wort will need to be with caution.« less

Detection and quality of previously undetermined Floridan aquifer system discharge to the St. Johns River, Jacksonville, to Green Cove Springs, northeastern Florida

USGS Publications Warehouse

Spechler, R.M.

1996-01-01

Potentiometric surface maps of the Upper Floridan aquifer show two depressions around the St. Johns River frm the city of Jacksonville south toward Green Cove Springs. These depressions, depending on their locations, are the result of withdrawals from agricultural, industrial, domestic and public-supply wells, diffuse upward leakage, and discharge from springs. Submerged springs that discharge into the St. Johns River between Jacksonville and Green Cove Springs have been thought to exist, but locating and evaluating these springs had not been attempted before this investigation. Thermal infrared imagery, seismic reflection, and numerous interviews with local residents were used to locate springs. An airborne thermal infrared survey was conducted along a section of the St. Johns River in northeastern Florida during February 1992 to detect possible sources of ground-water discharge to the river. An infrared image displayed one thermal anomaly in the St. Johns River which is associated with a previously unknown spring discharge from the Floridan aquifer system. Thermal anomalies also were observed at six locations where municipal facilities discharge treated wastewater to the river. Results of seismic reflection surveys indicate the presence of collapse and other karst features underlying the St. Johns River. These features indicate that the surficial deposits and the Hawthorn Formation that underlie the river probably do not consist of continuous beds. The collapse or deformation of the Hawthorn Formation or the presence of permeable sediment of localized extent could create zones of relatively high vertical leakance. This could provide a more direct hydraulic connection between the Upper Floridan aquifer and the river. Water samples collected from the only submerged spring in the St. Johns River within the Jacksonville-Green Cove Springs reach indicate that the source of the water is the Floridan aquifer system. Chloride and sulfate concentrations were 12 and 340 milligrams per liter, respectively. Specific conductance was 826 microsiemens per centimeter and the temperature of the water discharging from the spring was 25.1 degrees Celsius. The ratio of 87 Strontium/86 Strontium also indicates that the springwater has been in contact with rock materials of Eocene age, providing additional evidence that the springwater is derived from the Floridan aquifer system.

75 FR 68662 - Environmental Impact Statement: St. Louis County, MO

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-08

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Environmental Impact Statement: St... Hanley Road southeastward to River Des Peres Boulevard and Lansdowne Avenue in St. Louis County, Missouri...: Mr. John Hicks, Transportation Development Analyst, St. Louis County Department of Highways and...

Man and the Biosphere: Ground Truthing Coral Reefs for the St. John Island Biosphere Reserve.

ERIC Educational Resources Information Center

Brody, Michael J.; And Others

Research on the coral species composition of St. John's reefs in the Virgin Islands was conducted through the School for Field Studies (SFS) Coral Reef Ecology course (winter 1984). A cooperative study program based on the United Nations Educational, Scientific, and Cultural Organization's (Unesco) program, Man and the Biosphere, was undertaken by…

On Parle Francais Ici: The People of the St. John Valley Have a Tremendous Advantage.

ERIC Educational Resources Information Center

Banville, Beurmond J.

1995-01-01

A change in philosophy concerning the maintenance of native languages has led to local efforts to revive the French language in the St. John Valley (Maine), including the formation of a community organization and implementation of language programs in which children in all grades receive daily instruction in French. (LP)

A comparison of patterns of spontaneous adverse drug reaction reporting with St. John's Wort and fluoxetine during the period 2000-2013.

PubMed

Hoban, Claire L; Byard, Roger W; Musgrave, Ian F

2015-07-01

Herbal medicines are perceived to be safe by the general public and medical practitioners, despite abundant evidence from clinical trials and case reports that show herbal preparations can have significant adverse effects. The overall impact of adverse events to herbal medicines in Australia is currently unknown. Post marketing surveillance of medications through spontaneous adverse drug reaction (ADR) reports to the Therapeutic Goods Administration (TGA) is one way to estimate this risk. The patterns of spontaneously reported ADRs provide insight to herbal dangers, especially when compared with patterns of a mechanistically similar conventional drug. The study compared the pattern of spontaneously reported ADRs to St. John's Wort (Hypericum perforatum), a common herbal treatment for depression which contains selective serotonin reuptake inhibitors (SSRI), to fluoxetine, a commonly prescribed synthetic SSRI antidepressant. Spontaneous ADR reports sent to the TGA between 2000-2013 for St. John's Wort (n = 84) and fluoxetine (n = 447) were obtained and analysed. The demographic information, types of interaction, severity of the ADR, and the body systems affected (using the Anatomical Therapeutic Chemical classification system) were recorded for individual ADR cases. The majority of spontaneously reported ADRs for St. John's Wort and fluoxetine were concerning females aged 26-50 years (28.6%, 22.8%). The organ systems affected by ADRs to St John's Wort and fluoxetine have a similar profile, with the majority of cases affecting the central nervous system (45.2%, 61.7%). This result demonstrates that herbal preparations can result in ADRs similar to those of prescription medications. © 2015 Wiley Publishing Asia Pty Ltd.

75 FR 14481 - Environmental Impact Statement; Houma-Thibodaux to LA 3127 Connection; Terrebonne, Lafourche...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-25

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Environmental Impact Statement; Houma-Thibodaux to LA 3127 Connection; Terrebonne, Lafourche, Assumption, St. James, St. John the Baptist, St. Charles, and St. Mary Parishes, LA AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Revised...

Spatio-temporal analysis of wildfire ignitions in the St. Johns River Water Management District, Florida

Treesearch

Marc G. Genton; David T. Butry; Marcia L. Gumpertz; Jeffrey P. Prestemon

2006-01-01

We analyse the spatio-temporal structure of wildfire ignitions in the St. Johns River Water Management District in north-eastern Florida. We show, using tools to analyse point patterns (e.g. the L-function), that wildfire events occur in clusters. Clustering of these events correlates with irregular distribution of fire ignitions, including lightning...

Race on the Occoquan: A President's Second Freshman Year

ERIC Educational Resources Information Center

Martin, Roger H.

2008-01-01

In this article, the author relates his experiences as a second-time college freshman at St. John's College in Annapolis, Maryland. The author is a college president over the age of 50. He was also a melanoma cancer survivor who had underwent a lung surgery and chemotherapy four summers earlier. Chris Nelson, president of St. John's, had agreed to…

75 FR 6047 - Announcement of Funding Awards for Fiscal Year 2009 for the Housing Choice Voucher Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-05

...,702 CONCORDIA PARISH POLICE JURY.... 4001 CARTER STREET, ROOM 1, VIDALIA, LA 2 5,014 71373. ST JOHN... PARISH POLICE JURY.... 4001 CARTER STREET, ROOM 1, VIDALIA, LA 0 400 71373. ST JOHN THE BAPTIST PARISH HA... 152 JOE PARQUET CIRCLE, LAPLACE, LA 70068... 0 400 UNION PARISH POLICE JURY........ P. O. BOX 723...

Complexity of nearshore strontium-to-calcium ratio variability in a core sample of the massive coral Siderastrea siderea obtained in Coral Bay, St. John, U.S. Virgin Islands

USGS Publications Warehouse

Reich, Christopher D.; Kuffner, Ilsa B.; Hickey, T. Don; Morrison, Jennifer M.; Flannery, Jennifer A.

2013-01-01

Strontium-to-calcium ratios (Sr/Ca) were measured on the skeletal matrix of a core sample from a colony of the massive coral Siderastrea siderea collected in Coral Bay, St. John, U.S. Virgin Islands. Strontium and calcium are incorporated into the coral skeleton during the precipitation of aragonite by the coral polyps and their ratio is highly temperature dependent. The robustness of this temperature dependence makes Sr/Ca a reliable proxy for sea surface temperature (SST). Details presented from the St. John S. siderea core indicate that terrestrial inputs of sediment and freshwater can disrupt the chemical balance and subsequently complicate the utility of Sr/Ca in reconstructing historical SST. An approximately 44-year-long record of Sr/Ca shows that an annual SST signal is recorded but with an increasing Sr/Ca trend from 1980 to present, which is likely the result of runoff from the mountainous terrain of St. John. The overwhelming influence of the terrestrial fingerprint on local seawater chemistry makes utilizing Sr/Ca as a SST proxy in nearshore environments very difficult.

A GIS model of habitat suitability for Solanum conocarpum (Solanaceae) in St. John, US Virgin Islands

USGS Publications Warehouse

Palumbo, Matthew D.; Fleming, Jonathan P.; Monsegur, Omar A.; Vilella, Francisco

2016-01-01

Solanum conocarpum (Solanaceae) (Marron Bacora) is a rare, dry-forest shrub endemic to the island of St. John, US Virgin Islands, considered for listing under the Endangered Species Act. Given its status as a species of conservation concern, we incorporated environmental characteristics of 3 observed populations and 5 additional known locations into a geographic information system (GIS) analysis to create a habitat-suitability model for the species on the island of St. John. Our model identified 1929.87 ha of highly suitable and moderately suitable habitat. Of these, 1161.20 ha (60.2%) occurred within the boundaries of Virgin Islands National Park. Our model provides spatial information on potential locations for future surveys and restoration sites for this endemic species of the US Virgin Islands.

40 CFR 81.356 - Virgin Islands.

Code of Federal Regulations, 2010 CFR

2010-07-01

... standards Cannot be classified Better than national standards Virgin Islands AQCR: St. Croix (southern) 1 X... Area Designation Date 1 Type Classification Date 1 Type Statewide Unclassifiable/Attainment St. Croix St. John St. Thomas 1 This date is November 15, 1990, unless otherwise noted. Virgin Islands—Ozone (1...

77 FR 34404 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-11

... Constitution Ave., Hartford, 12000359 Kensington Grammar School--Jean E. Hooker High School, 462 Alling St..., 12000365 St. Johns County Constitution Obelisk, Plaza de la Constitution, St. Augustine, 12000364 NEW YORK...

Bucking the Trend, St. John's University Converts Instructors into Tenure-Track Professors

ERIC Educational Resources Information Center

June, Audrey Williams

2009-01-01

Scholars who teach composition, a staple on the schedule of many a college freshman, often wind up stringing together a series of adjunct teaching jobs while keeping an eye out for that first step on the golden track to tenure. This article reports on a group of 20 people hired by St. John's University to teach in its first-year writing program,…

Phytosociology of vascular plants on an international biosphere reserve: Virgin Islands National Park, St. John, US Virgin Islands

Treesearch

Sonja N. Oswalt; Thomas J. Brandies; Britta P. Dimick

2006-01-01

We investigated the relationships of vegetation communities to environmental variables and compared the relative contribution of native and introduced species in extant forest communities on St. John, US Virgin Islands, using an island-wide forest vegetation inventory and monitoring network of permanent plots. We detected 2,415 individuals of 203 species, 5 percent of...

Phytosociology of Vascular Plants on an International Biosphere Reserve: Virgin Islands National Park, St. John, US Virgin Islands.

Treesearch

Sonja N. Oswalt; Thomas J. Brandeis; Britta P. Dimick

2006-01-01

We investigated the relationships of vegetation communities to environmental variables and compared the relative contribution of native and introduced species in extant forest communities on St. John, US Virgin Islands, using an island-wide forest vegetation inventory and monitoring network of permanent plots. We detected 2,415 individuals of 203 species, 5 percent of...

Monoamine oxidase A inhibitor occupancy during treatment of major depressive episodes with moclobemide or St. John's wort: an [11C]-harmine PET study.

PubMed

Sacher, Julia; Houle, Sylvain; Parkes, Jun; Rusjan, Pablo; Sagrati, Sandra; Wilson, Alan A; Meyer, Jeffrey H

2011-11-01

Monoamine oxidase A (MAO-A) inhibitor antidepressants raise levels of multiple monoamines, whereas the selective serotonin reuptake inhibitors (SSRIs) only raise extracellular serotonin. Despite this advantage of MAO-A inhibitors, there is much less frequent development of MAO inhibitors compared with SSRIs. We sought to measure brain MAO-A occupancy after 6 weeks of treatment in depressed patients with a clinically effective dose of a selective MAO-A inhibitor and measure MAO-A occupancy after repeated administration of St. John's wort, an herb purported to have MAO-A inhibitor properties. Participants underwent 2 [(11)C]-harmine positron emission tomography scans. Healthy controls completed a test-retest condition, and depressed patients were scanned before and after repeated administration of moclobemide or St. John's wort for 6 weeks at the assigned dose. We measured MAO-A VT, an index of MAO-A density, in the prefrontal, anterior cingulate and anterior temporal cortices, putamen, thalamus, midbrain and hippocampus. We included 23 participants (10 controls and 13 patients with major depressive disorder [MDD]) in our study. Monoamine oxidase A VT decreased significantly throughout all regions after moclobemide treatment in patients with MDD compared with controls (repeated-measures analysis of variance, F1,15 = 71.08-130.06, p < 0.001 for all regions, mean occupancy 74% [standard deviation 6%]). Treatment with St. John's wort did not significantly alter MAO-A VT. The occupancy estimates are limited by the sample size of each treatment group; hence, our estimate for the overall moclobemide occupancy of 74% has a 95% confidence interval of 70%-78%, and we can estimate with 95% certainty that the occupancy of St. John's wort is less than 5%. For new MAO-A inhibitors, about 74% occupancy at steady-state dosing is desirable. Consistent with this, St. John's wort should not be classified as an MAO-A inhibitor. The magnitude of MAO-A blockade during moclobemide treatment exceeds the elevation of MAO-A binding during illness by at least 30%, suggesting that the treatment effect should exceed the disease effect when designing selective antidepressants for this target. © 2011 Canadian Medical Association

Potential for interaction of kava and St. John's wort with drugs.

PubMed

Singh, Yadhu N

2005-08-22

The present interest and widespread use of herbal remedies has created the possibility of interaction between them and pharmaceutical drugs if they are used simultaneously. Before the recent reports of apparent hepatotoxicity associated with its use, kava (Piper methysticum Forst. F.), was one of the top 10 selling herbal remedies in Europe and North America. This adverse effect was not previously encountered with the traditional beverage which was prepared as a water infusion in contrast to the commercial products which are extracted with organic solvents. Kavalactones, the active principles in kava, are potent inhibitors of several of the CYP 450 enzymes, suggesting a high potential for causing pharmacokinetic interactions with drugs and other herbs which are metabolized by the same CYP 450 enzymes. Furthermore, some kavalactones have been shown to possess pharmacological effects, such as blockade of GABA receptors and sodium and calcium ion channels, which may lead to pharmacodynamic interactions with other substances which possess similar pharmacological proprieties. St. John's wort (Hypericum perforatum L.), used extensively for the treatment of mild to moderate clinical depression, has long been considered safer than the conventional pharmaceutical agents. However, its ability, through its active constituents hypericin, pseudohypericin and hyperforin, to induce intestinal P-glycoprotein/MRD1 and both intestinal and hepatic CYP3A4 enzyme, could markedly reduce the distribution and disposition of their co-substrates. In addition, St. John's wort is a potent uptake inhibitor of the neurotransmitters serotonin, norepinephrine and dopamine all of which have a role in mood control. Consequently, the very real potential for a pharmacodynamic interaction between the herb and pharmaceutical drugs which share this mechanism of action and, like St. John's wort, are used for mood elevation. However, presently there is very little evidence to substantiate actual pharmacokinetic and/or pharmacodynamic interaction between drugs and kava or St. John's wort. This review provides a brief overview of the existing data on interactions of kava and St. John's wort with pharmaceutical agents and as a result reveals the urgent need for detailed investigations to identify clinically significant interactions for these herbal remedies that have the potential to cause adverse effects.

Effect of the St. John's wort constituent hyperforin on docetaxel metabolism by human hepatocyte cultures.

PubMed

Komoroski, Bernard J; Parise, Robert A; Egorin, Merrill J; Strom, Stephen C; Venkataramanan, Raman

2005-10-01

St. John's wort is a commonly used herbal medication that increases cytochrome P450 3A (CYP3A) activity. Because docetaxel is inactivated by CYP3A, we studied the effects of the St. John's wort constituent hyperforin on docetaxel metabolism in a human hepatocyte model. Hepatocytes, isolated from three donor livers, were exposed to hyperforin (0.1, 0.5, or 1.5 micromol/L) or rifampin (10 micromol/L) for 48 hours. After 48 hours, hyperforin- or rifampin-containing medium was replaced with medium containing 100 micromol/L docetaxel. After 1 hour, docetaxel metabolism was characterized by liquid chromatography-tandem mass spectrometry. Subsequent incubations characterized the specific cytochrome P450s that produced the docetaxel metabolites observed in hepatocyte incubations. Rifampin induced docetaxel metabolism 6.8- to 32-fold above docetaxel metabolism in control cultures. Hyperforin induced docetaxel metabolism in all three hepatocyte preparations. Hyperforin induction was dose-dependent and, at maximum, was 2.6- to 7-fold greater than that in controls. Docetaxel metabolites identified in rifampin- and hyperforin-treated hepatocyte preparations included the previously described tert-butyl-hydroxylated metabolite and two previously unidentified metabolites involving hydroxylation on the baccatin ring. CYP3A4 produced the tert-butyl-hydroxylated metabolite and the two ring-hydroxylated metabolites. CYP2C8 produced one of the newly described ring-hydroxylated metabolites. Exposure to the St. John's wort constituent hyperforin induces docetaxel metabolism in vitro. This implies that subtherapeutic docetaxel concentrations may result when docetaxel is administered to patients using St. John's wort on a chronic basis. The results also show induction of previously undescribed metabolic pathways for docetaxel, one of which may be analogous to the known 6-alpha-hydroxylation of paclitaxel by CYP2C8.

[Effects of different tillage patterns on soil properties, maize yield and water use efficiency in Weibei Highland, China.

PubMed

Liu, Dan; Zhang, Xia; Li, Jun; Wang, Xu-Dong

2018-02-01

An eight-year field experiment of straw returning was conducted on dark loessial soil in Weibei Highland to investigate the effects of tillage patterns on soil aggregate, soil organic carbon (SOC), corn yield and soil water use efficiency (WUE). There were six tillage patterns, including conventional tillage (CT/CT), no-tillage (NT/NT), subsoiling tillage (ST/ST), no-tillage/subsoiling tillage (NT/ST), conventional tillage/no-tillage (CT/NT) and conventional tillage/subsoiling tillage (CT/ST). The results showed that compared with CT/CT, the patterns of NT/NT, ST/ST and the rotational tillage patterns (NT/ST, CT/NT and CT/ST) decreased the mean mass diameter of soil mechanical stable aggregate. The patterns of NT/NT, ST/ST and NT/ST increased the content of soil water-stable aggregate with the particle size >0.25 mm (WR 0.25 ) and their mean mass diameter, especially in the depth of 20-50 cm. These patterns reduced the proportion of aggregate destruction (PAD). Compared with CT/CT, the patterns of NT/ST, CT/NT, NT/NT and ST/ST increased the content of SOC in 0-10 cm soil layer. The content of SOC decreased as the increases of soil depth for all tillage patterns, but the decrease in SOC of three single tillage patterns (ST/ST, NT/NT and CT/CT) was larger than that of three rotational tillage patterns. Compared with CT/CT, the other five tillage patterns increased soil water storage in 0-200 cm soil profile, crop yield and WUE in maize. The yield and WUE in NT/ST pattern were significantly increased by 15.1% and 27.5%, respectively. Both corn yield and WUE were significantly and positively correlated with soil water storage in 0-200 cm soil profile in field during the cropping and fallow periods. Moreover, soil water storage during the cropping period was positively correlated with WR 0.25 , but negatively correlated with PAD in 0-50 cm soil layer. Particularly, maize yield, WUE and soil water storage during the cropping period were closely related to WR 0.25 in 20-50 cm soil layer and PAD. Both WUE and soil water storage during the cropping period was correlated with the SOC content in 0-10 cm soil layer. With respect to the soil properties, crop yield and WUE, the tillage pattern of NT/ST was the best stratety in dark loessial soil for spring maize growth in Weibei Highland.

Potentiometric surface map of the Floridan Aquifer in the St Johns River Water Management District and vicinity, Florida, September, 1977

USGS Publications Warehouse

Watkins, F.A.; Laughlin, C.P.; Hayes, E.C.

1977-01-01

This map presents the potentiometric surface of the Floridan aquifer in the St. Johns River Water Management District and vicinity for September 1977. The Floridan aquifer is the principal source of potable water in the area. Water-level measurements were made on approximately 900 wells and springs. The potentiometric surface is shown by 5-foot contours except in the Fernandina Beach area where 10- and 20-foot contours are used to show the deep cone of depression. This is the first map covering the entire St. Johns River Water Management District and vicinity for September, a high water-level period. The potentiometric surface ranged from 130 feet above mean sea level in Polk County to 131 feet below sea level in Nassau County. (Woodard-USGS)

Lightening the Load

DTIC Science & Technology

2007-09-09

Research, Engineering and Systems) Dr. John C. Sommerer NRAC, Vice Chair; Director, S&T, Johns Hopkins Applied Physics Laboratory Dr. Walt...O’Donohue, Staff Officer General Dynamics Robotic Systems John H. Northrop & Associates Mr. John H. Northrop, Executive Director General Dynamics...Equipment, US Army LtCol John Lemondes, PM Soldier as a System LTL Efforts US Army Mr. Bob Conklin, Staff UK LTL Efforts Equipment Capability

Comprehensive Transit Plan for the Virgin Islands - Technical Report

DOT National Transportation Integrated Search

1989-01-01

This report contains a description of the elements and recommendations of a transportation study of the islands of St. Thomas, St. Croix, and St. John in the U.S. Virgin Island archipelago. An extensive data collection effort, including traffic volum...

The National Wetland Plant List

DTIC Science & Technology

2012-10-01

P. Adams FACW Florida Sands St. John’s-Wort Hypericum fasciculatum Lam. FACW FACW FACW Peel -Bark St. John’s-Wort Hypericum fraseri...Dewflower Musa X paradisiaca L. (pro sp.) UPL FAC FACU Musa acuminata Colla FACW Edible Banana Musa troglodytarum L. FACU Fe’i... Banana Myoporum laetum G. Forst. FACU UPL Ngaio-Tree Myosotis arvensis (L.) Hill FAC FAC UPL FAC FAC FACU FACU Rough Forget-Me-Not

Contribution of Dead Wood to Biomass and Carbon Stocks in the Caribbean: St. John, U.S. Virgin Islands.

Treesearch

Sonja N. Oswalt; Thomas J. Brandeis

2008-01-01

Dead wood is a substantial carbon stock in terrestrial forest ecosystems and hence a critical component of global carbon cycles. Given the limited amounts of dead wood biomass and carbon stock information for Caribbean forests, our objectives were to: (1) describe the relative contribution of down woody materials (DWM) to carbon stocks on the island of St. John; (2)...

Contribution of dead wood to biomass and carbon stocks in the Caribbean: St. John, U.S. Virgin Islands

Treesearch

Sonja N. Oswalt; Thomas J. Brandeis

2008-01-01

Dead wood is a substantial carbon stock in terrestrial forest ecosystems and hence a critical component of global carbon cycles. Given the limited amounts of dead wood biomass and carbon stock information for Caribbean forests, our objectives were to: (1) describe the relative contribution of down woody materials (DWM) to carbon stocks on the island of St. John; (2)...

Suppurative peritonitis by Klebsiella pneumoniae in captive gold-handed tamarin (Saguinus midas midas).

PubMed

Guerra, Maria F L; Teixeira, Rodrigo H F; Ribeiro, Vanessa L; Cunha, Marcos P V; Oliveira, Maria G X; Davies, Yamê M; Silva, Ketrin C; Silva, Ana P S; Lincopan, Nilton; Moreno, Andrea M; Knöbl, Terezinha

2016-02-01

This report describes an outbreak of suppurative peritonitis caused by Klebsiella pneumoniae in an adult female of captive golden-handed tamarin (Saguinus midas midas). Two virulent and multidrug-resistant strains were isolated and classified through MLST as ST60 and ST1263. The microbiological diagnosis works as a support tool for preventive measures. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

40 CFR 52.2780 - Control strategy for sulfur oxides.

Code of Federal Regulations, 2010 CFR

2010-07-01

... maintenance of the national ambient air quality standards for sulfur oxides on the island of St. Croix. (b...) The entire regulation as it applies to the islands of St. Thomas and St. John. (2) The entire... island of St. Croix. (3) The entire regulation excluding subsection (a)(2) as it applies to the remaining...

Relative abundance, habitat use, and long-term population changes of wintering and resident landbirds on St. John, U.S. Virgin Islands

Treesearch

D.W. Steadman; J.R. Montambault; Scott K. Robinson; S.N. Oswalt; T.J. Brandeis; A. Gustavo Londoño; M.J. Reetz; W.M. Schelsky; N.A. Wright; J.P. Hoover; J. Jankowski; A.W. Kratter; A.E. Martinez; J. Smith

2009-01-01

St. John, U.S. Virgin Islands, is one of the most forested islands in the West Indies and provides an opportunity to conserve both resident birds and wintering neotropical migrants.We conducted double-observer point counts of landbirds in December 2005 and 2006 in Forest Inventory and Analysis (FIA) plots and National] Park Service (NPS) trails in Virgin Islands...

A Summary of 20 Years of Forest Monitoring in Cinnamon Bay Watershed, St. John, U.S. Virgin Islands.

Treesearch

Peter L. Weaver

2006-01-01

St. John, and probably the Cinnamon Bay watershed, has a history of human use dating to 1700 B.C. The most notable impacts, however, occurred from 1730 to 1780 when sugar cane and cotton production peaked on the island. As agriculture was abandoned, the island regenerated in secondary forest, and in 1956, the Virgin Islands National Park was created. From 1983 to 2003...

Pharmacological activity of three commercial Hypericum perforatum preparations in mice.

PubMed

Jean, D; Pouligon, M; Henriot, A C

2006-08-01

St John's Wort (Hypericum perforatum) is the main herbal species used to treat depression. The products available on the pharmaceutical and dietary supplement markets are obtained by a variety of preparation processes and their pharmacological effects may differ significantly. The purpose of this study therefore was to investigate the effect of different St John's Wort commercial preparations available on the French market. Only one preparation gave significant results in the forced swimming test.

Relative abundance, habitat use, and long-term population changes of wintering and resident landbirds on St. John, U.S. Virgin Islands

Treesearch

David Steadman; Jensen Montambault; Scott Robinson; Sonja Oswalt; Thomas Brandeis; Agustavo Londono; Matthew Reetz; Wendy Schelsky; Natalie Wright; Jeffrey Hoover; Jill Jankowski; Andrew Kratter; Arie Martínez; Jordan Smith

2009-01-01

St. John, U.S. Virgin Islands, is one of the most forested islands in the West Indies and provides an opportunity to conserve both resident birds and wintering neotropical migrants.We conducted double-observer point counts of landbirds in December 2005 and 2006 in Forest Inventory and Analysis (FIA) plots and National Park Service (NPS) trails in Virgin Islands...

A history of erotic philosophy.

PubMed

Soble, Alan

2009-01-01

This essay historically explores philosophical views about the nature and significance of human sexuality, starting with the Ancient Greeks and ending with late 20th-century Western philosophy. Important figures from the history of philosophy (and theology) discussed include Sappho, Plato, Aristotle, St. Augustine, St. Jerome, the Pelagians, St. Thomas Aquinas, Michel de Montaigne, Rene Descartes, Thomas Hobbes, David Hume, Immanuel Kant, Søren Kierkegaard, Arthur Schopenhauer, Jeremy Bentham, John Stuart Mill, Karl Marx, Friedrich Engels, Sigmund Freud, Jean-Paul Sartre, Simone de Beauvoir, Wilhelm Reich, and Herbert Marcuse. Contemporary philosophers whose recent work is discussed include Michel Foucault, Thomas Nagel, Roger Scruton, Karol Wojtyla (Pope John Paul II), Catharine MacKinnon, Richard Posner, and John Finnis. To show the unity of the humanities, the writings of various literary figures are incorporated into this history, including Mark Twain, Arthur Miller, James Thurber, E. B. White, Iris Murdoch, and Philip Roth.

IJME Fifth National Bioethics Conference: a summary report.

PubMed

Saligram, Prasanna; Kurpad, Sunita Simon; Narayan, Thelma

2015-01-01

The Fifth National Bioethics Conference (NBC) was co-hosted by St John's National Academy of Health Sciences (SJNAHS), Bangalore; Society for Community Health Research Awareness and Action (SOCHARA), Bangalore; and Forum for Medical Ethics Society (FMES), Mumbai, which publishes the Indian Journal of Medical Ethics (IJME). The conference was held at the St John's campus, Bangalore from December 11 to 13, 2014. The theme of the Fifth NBC was "Integrity in medical care, public health, and health research".

JPRS Report, Epidemiology.

DTIC Science & Technology

1989-12-13

Measles Outbreak Shows Need for Immunization [ Paul Taylor; Toronto THE GLOBE AND MAIL, 13 Sep 89] 19 Meningitis Blamed in Port Hope Student’s Death...or two centres, as in other provinces, but is spread over a large number of hospitals. New Brunswick: From 20 to 30 percent of patients at St. John ...shortage of hospital and hospital beds for out-of-town patients. Those who can afford it choose to travel to St. John and stay in a hotel during

Modeling and Analysis of Sea-level Rise Impacts on Salinity in the Lower St. Johns River

NASA Astrophysics Data System (ADS)

Bacopoulos, P.

2015-12-01

There is deliberate attention being paid to studying sea-level rise impacts on the lower St. Johns River, a drowned coastal plain-type estuary with low topographic drive, located in northeastern Florida. One area of attention is salinity in the river, which influences the entire food web, including sea and marsh grasses, juvenile crustaceans and fishes, wading birds and migratory waterfowl, marine mammals and other predator animals. It is expected that elevated ocean levels will increase the salinity of the estuarine waters, leading to deleterious effects on dependent species of the river biology. The objective of the modeling and analysis was: 1) to establish baseline conditions of salinity for the lower St. Johns River; and 2) to examine future conditions of salinity, as impacted by sea-level rise. Establishing baseline conditions entailed validation of the model for present-day salinity in the lower St. Johns River via comparison to available data. Examining future conditions entailed application of the model for sea-level rise scenarios, with comparison to the baseline conditions, for evaluation of sea-level rise impacts on salinity. While the central focus was on the physics of sea-level rise impacts on salinity, some level of salinity-biological assessment was conducted to identify sea-level rise/salinity thresholds, as related to negatively impacting different species of the river biology.

Project REACH. Regional Education To Achieve with Company Help. Performance Report.

ERIC Educational Resources Information Center

Parkway School District, Chesterfield, MO.

Parkway Area Adult Basic Education Program formed a partnership with St. John's Mercy Medical Center, St. Luke's Hospital, Watlow Electric, Missouri Department of Elementary and Secondary Education, and Literacy Council of Greater St. Louis to develop a model National Workplace Literacy Program. The instructional model developed under Project…

Of reef fishes, overfishing and in situ observations of fish traps in St. John, U.S. Virgin Islands

USGS Publications Warehouse

Garrison, Virginia H.; Rogers, Caroline S.; Beets, J.

1998-01-01

Fishing with a variety of methods and gears, including traps, is allowed within the waters of Virgin Islands National Park (St. 10hn, U.S. Virgin Islands). Randall's 1 9 6 1 observation of the effects of overushing in nearshore waters off Sto John has been followed by three and a half decades of reports documenting the declining reef fish catch in the Virgin Islands and much of the Caribbean. To assess the state of the trap fishery in St. John waters, traps set by fishers were visually censused in situ in 1992, 1993 and 1994 both inside and outside park waters. Fifty-nine species of fishes representing 23 families and 1340 individuals were identified from 285 traps set in five habitat types (coral reef, octocoral hard-bottom, seagrass beds, algal plains and non-living substrate). The greatest number of observed traps were in algal plain (31%) and gorgonian habitat (27%), pointing to greater exploitation of deeper, non­ coral habitats. Coral habitat accounted for the most species trapped (41), whereas the mean number of fishes per trap was highest in algal plain (5.7, se=0.6). Six species made up 51% of all fish observed in traps. The Acanthuridae was the most abundant family. Species composition and number of fishes per trap were similar inside and outside park waters. Scarids and serranids were more frequently observed in traps inside the park. Between 1992 and 1994. patterns in the data emerged: smaller numbers of fish per trap; shifts to smaller size classes; fewer serranids, lutjanids, sparids, and balistids, and all feeding guilds except herbivores per trap; more acanthurids per trap. Compared with other trap data from the Virgin Islands and the Caribbean - Florida region, the mean number of fish and biomass per St. John trap are low, serranid numbers are low, and acanthurid and herbivore numbers are high. The reef-associated fishes of St. John appear to be overexploited.

St. John's Wort

MedlinePlus

... Berner MM, Kriston L. St. John’s wort for major depression. Cochrane Database of Systematic Reviews. 2008;(4):CD000448 [ ... Hypericum perforatum) versus sertraline and placebo in major depressive disorder: continuation data from a 26-week RCT . Pharmacopsychiatry. ...

St. John's Wort and Depression

MedlinePlus

... Health (NIMH) Web page on depression . What the Science Says About the Effectiveness of St.  John’s Wort ... that is separate from the treatment. What the Science Says About the Safety and Side Effects of ...

Potentiometric surface of the Floridan Aquifer and its use in management of water resources, St. Johns River Water Management District, Florida

USGS Publications Warehouse

Rodis, Harry George; Munch, D.A.

1983-01-01

The Floridan aquifer supplies most of the fresh groundwater for municipal, industrial, and agricultural uses within the 12,400 sq mi St. Johns River Water Management District. Because of the growing demand for water and the variation in rainfall, resource managers need timely information on short-term and long-term changes in the availability of fresh water. The purpose of this report is to explain potentiometric surface maps and their value in assessing the resource, particularly during drought conditions. The Floridan aquifer is recharged by rainfall falling directly on the outcrop of the aquifer, and, where the aquifer is overlain by the surficial aquifer with the water table above the potentiometric surface of the Floridan, by water infiltrating downward from the overlying surficial aquifer. Water is discharged by pumping and free-flowing wells, springflow, and upward leakage into overlying formations, streams, and lakes or into the ocean. Fluctuations in the potentiometric surface reflect net gains (recharge) or losses (discharge) of water stored in the aquifer. Net gains occur during the wet season (June through September) when recharge exceeds discharge and causes the potentiometric surface to rise in most places. Net losses in storage, and declines in the potentiometric surface, follow during the dry season (October through May) when discharge exceeds recharge. Seasonal changes in the potentiometric surface, based on a 2-yr average of water level measurements during May and September 1977, and May and September 1978, are illustrated. Two of the greater long-term declines in the potentiometric surface have occurred in the growing metropolitan areas of Jacksonville and Orlando-Winter Park, the two largest public suppliers of water in the Water Management District. Municipal pumpage increased in Jacksonville from 37 million gallons per day (mgd) in 1961 to 56 mgd in 1980. The increased pumpage and a deficiency in rainfall of 15.8 inches contributed to a decline in the potentiometric surface of as much as 15 ft. Orlando-Winter Park municipal pumpage increasing from 27 mgd in 1961 to 62 mgd in 1980. The periodic preparation of maps showing changes in the potentiometric surface of the aquifer provide the best base information for both short-term and long-term management of the water resources in the St. Johns River Water Management District. (Lantz-PTT)

Planning applications in east central Florida. [St. Johns National Wildlife Refuge

NASA Technical Reports Server (NTRS)

Hannah, J. W.; Thomas, G. L.; Esparza, F. (Principal Investigator); Millard, J. J.

1975-01-01

The author has identified the following significant results. St. Johns National Wildlife Refuge, a 4000 acre marsh, was established primarily to protect the Dusky Seaside Sparrow. A vegetation map of the refuge based on ground observations and color infrared photography was made. The preferred habitat of this sparrow is high-to-medium density spartina (a marsh grass) with no trees nearby. An increase in spartina density corresponds to an increase in marsh wetness. A thematic map shows the birds habitat preferences.

Proceedings of the Workshop on Aquatic Ecosystem Modeling and Assessment Techniques for Application within the U.S. Army Corps of Engineers.

DTIC Science & Technology

1998-04-01

Dr. Kennedy. Others who contributed directly to planning for the workshop included Drs. Todd S. Bridges, Mark S. Dortch, John M. Nestler, and...Quality and Contaminants Modeling Branch, EPED; Dr. Price, Chief, EPED; and Dr. John Harrison, Director, EL. At the time of the publication of this...this project is characterized by broad multi- agency interest and involvement, including several USACE Districts (St Paul , Rock Island, St, Louis

A silicone rubber based composites using n-octadecane/poly (styrene-methyl methacrylate) microcapsules as energy storage particle

NASA Astrophysics Data System (ADS)

Wu, W. L.; Chen, Z.

A phase-change energy-storage material, silicone rubber (SR) coated n-octadecane/poly (styrene-methyl methacrylate) (SR/OD/P(St-MMA)) microcapsule composites, was prepared by mixing SR and OD/P(St-MMA) microcapsules. The microcapsule content and silicone rubber coated method were investigated. The morphology and thermal properties of the composites were characterized by scanning electron microscopy (SEM), thermogravimetric analysis (TG), differential scanning calorimetry (DSC) and heat storage properties. The results showed that the thermal and mechanical properties of SR/OD/P(St-MMA) composites were excellent when the microcapsules were coated with room temperature vulcanized silicone rubber (RTVSR), of which content was 2 phr (per hundred rubber). The enthalpy value of the composites was 67.6 J g-1 and the composites were found to have good energy storage function.

Conservation of polypyrimidine tract binding proteins and their putative target RNAs in several storage root crops.

PubMed

Kondhare, Kirtikumar R; Kumar, Amit; Hannapel, David J; Banerjee, Anjan K

2018-02-07

Polypyrimidine-tract binding proteins (PTBs) are ubiquitous RNA-binding proteins in plants and animals that play diverse role in RNA metabolic processes. PTB proteins bind to target RNAs through motifs rich in cytosine/uracil residues to fine-tune transcript metabolism. Among tuber and root crops, potato has been widely studied to understand the mobile signals that activate tuber development. Potato PTBs, designated as StPTB1 and StPTB6, function in a long-distance transport system by binding to specific mRNAs (StBEL5 and POTH1) to stabilize them and facilitate their movement from leaf to stolon, the site of tuber induction, where they activate tuber and root growth. Storage tubers and root crops are important sustenance food crops grown throughout the world. Despite the availability of genome sequence for sweet potato, cassava, carrot and sugar beet, the molecular mechanism of root-derived storage organ development remains completely unexplored. Considering the pivotal role of PTBs and their target RNAs in potato storage organ development, we propose that a similar mechanism may be prevalent in storage root crops as well. Through a bioinformatics survey utilizing available genome databases, we identify the orthologues of potato PTB proteins and two phloem-mobile RNAs, StBEL5 and POTH1, in five storage root crops - sweet potato, cassava, carrot, radish and sugar beet. Like potato, PTB1/6 type proteins from these storage root crops contain four conserved RNA Recognition Motifs (characteristic of RNA-binding PTBs) in their protein sequences. Further, 3´ UTR (untranslated region) analysis of BEL5 and POTH1 orthologues revealed the presence of several cytosine/uracil motifs, similar to those present in potato StBEL5 and POTH1 RNAs. Using RT-qPCR assays, we verified the presence of these related transcripts in leaf and root tissues of these five storage root crops. Similar to potato, BEL5-, PTB1/6- and POTH1-like orthologue RNAs from the aforementioned storage root crops exhibited differential accumulation patterns in leaf and storage root tissues. Our results suggest that the PTB1/6-like orthologues and their putative targets, BEL5- and POTH1-like mRNAs, from storage root crops could interact physically, similar to that in potato, and potentially, could function as key molecular signals controlling storage organ development in root crops.

Potentiometric Surface of the Upper Floridan Aquifer in the St. Johns River Water Management District and Vicinity, Florida, May 2005

USGS Publications Warehouse

Kinnaman, Sandra L.

2006-01-01

INTRODUCTION This map depicts the potentiometric surface of the upper Floridan aquifer in the St. Johns River Water Management District and vicinity for May 2005. Potentiometric contours are based on water level measurements collected at 598 wens during the period May 5 - 31, near the end of the dry season. Some contours are inferred from previous potentiometric-surface maps with larger well networks. The potentiometric surface of the carbonate upper Floridan aquifer responds mainly to rainfall, and more locally, to ground water withdrawals. Potentiometric-surface highs generally correspond to topographic highs where the aquifer is recharged. Springs and areas of diffuse upward leakage naturally discharge water from the aquifer and are most prevalent along the St. Johns River. Areas of discharge are reflected by depressions in the potentiometric surface. Ground water withdrawals locally have lowered the potentiometric surface. Ground water in the upper Floridan aquifer generally flows from potentiometric highs to potentiometric lows in a direction perpendicular to the contours.

Building on a legacy for the era of population health.

PubMed

Brady, Marla G

2014-01-01

The 2011 Joplin tornado was a catastrophic EF5 multiple-vortex tornado that struck Joplin, Missouri, late in the afternoon of Sunday, May 22, 2011. It was part of a larger, late-May tornado outbreak and reached a maximum width of nearly 1 mile (1.6 km) during its path through the city. Mercy St John's Hospital (which had recently joined Mercy Ministries) suffered a direct hit and was rendered nonuseable. A total of 183 patients and nearly 200 coworkers/staff members were evacuated from the building within the next 90 minutes. Triage centers were set up outside as hospitals of other areas opened their doors for St John's patients and community members who had been injured. The tornado in Joplin destroyed Mercy St John's Hospital. Given this future, why did Mercy Ministries choose to rebuild an acute care facility rather than merely an outpatient system? The organization considered current community needs and the needs of the future. They also remembered their mission and the legacy of their heritage.

Potentiometric Surface of the Upper Floridan Aquifer in the St. Johns River Water Management District and Vicinity, Florida, May 2009

USGS Publications Warehouse

Kinnaman, Sandra L.; Dixon, Joann F.

2009-01-01

This map depicts the potentiometric surface of the Upper Floridan aquifer in the St. Johns River Water Management District and vicinity for May 2009. Potentiometric contours are based on water-level measurements collected at 625 wells during the period May 14 - May 29, near the end of the dry season. Some contours are inferred from previous potentiometric-surface maps with larger well networks. The potentiometric surface of the carbonate Upper Floridan aquifer responds mainly to rainfall, and more locally, to groundwater withdrawals and spring flow. Potentiometric-surface highs generally correspond to topographic highs where the aquifer is recharged. Springs and areas of diffuse upward leakage naturally discharge water from the aquifer and are most prevalent along the St. Johns River. Areas of discharge are reflected by depressions in the potentiometric surface. Groundwater withdrawals locally have lowered the potentiometric surface. Groundwater in the Upper Floridan aquifer generally flows from potentiometric highs to potentiometric lows in a direction perpendicular to the contours.

Potentiometric Surface of the Upper Floridan Aquifer in the St. Johns River Water Management District and Vicinity, Florida, May 2006

USGS Publications Warehouse

Kinnaman, Sandra L.

2006-01-01

Introduction: This map depicts the potentiometric surface of the Upper Floridan aquifer in the St. Johns River Water Management District and vicinity for May 2006. Potentiometric contours are based on water-level measurements collected at 599 wells during the period May 14-31, near the end of the dry season. Some contours are inferred from previous potentiometric-surface maps with larger well networks. The potentiometric surface of the carbonate Upper Floridan aquifer responds mainly to rainfall, and more locally, to ground-water withdrawals and springflow. Potentiometric-surface highs generally correspond to topographic highs where the aquifer is recharged. Springs and areas of diffuse upward leakage naturally discharge water from the aquifer and are most prevalent along the St. Johns River. Areas of discharge are reflected by depressions in the potentiometric surface. Ground-water withdrawals locally have lowered the potentiometric surface. Ground water in the Upper Floridan aquifer generally flows from potentiometric highs to potentiometric lows in a direction perpendicular to the contours.

Potentiometric surface of the Upper Floridan aquifer in the St. Johns River water management district and vicinity, Florida, September 2005

USGS Publications Warehouse

Kinnaman, Sandra L.

2006-01-01

This map depicts the potentiometric surface of the Upper Floridan aquifer in the St. Johns River Water Management District and vicinity for September 2005. Potentiometric contours are based on water-level measurements collected at 643 wells during the period September 12-28, near the end of the wet season. Some contours are inferred from previous potentiometric-surface maps with larger well networks. The potentiometric surface of the carbonate Upper Floridan aquifer responds mainly to rainfall, and more locally, to ground-water withdrawals and springflow. Potentiometric-surface highs generally correspond to topographic highs where the aquifer is recharged. Springs and areas of diffuse upward leakage naturally discharge water from the aquifer and are most prevalent along the St. Johns River. Areas of discharge are reflected by depressions in the potentiometric surface. Ground-water withdrawals locally have lowered the potentiometric surface. Ground water in the Upper Floridan aquifer generally flows from potentiometric highs to potentiometric lows in a direction perpendicular to the contours.

Potentiometric Surface of the Upper Floridan Aquifer in the St. Johns River Water Management District and Vicinity, Florida, September 2006

USGS Publications Warehouse

Kinnaman, Sandra L.; Dixon, Joann F.

2007-01-01

Introduction This map depicts the potentiometric surface of the Upper Floridan aquifer in the St. Johns River Water Management District and vicinity for September 2006. Potentiometric contours are based on water-level measurements collected at 571 wells during the period September 11-29, near the end of the wet season. Some contours are inferred from previouspotentiometric-surface maps with larger well networks. The potentiometric surface of the carbonate Upper Floridan aquifer responds mainly to rainfall, and more locally, to ground-water withdrawals and spring flow. Potentiometric-surface highs generally correspond to topographic highs where the aquifer is recharged. Springs and areas of diffuse upward leakage naturally discharge water from the aquifer and are most prevalent along the St. Johns River. Areas of discharge are reflected by depressions in the potentiometric surface. Ground-water withdrawals locally have lowered the potentiometric surface. Ground water in the Upper Floridan aquifer generally flows from potentiometric highs to potentiometric lows in a direction perpendicular to the contours.

Potentiometric Surface of the Upper Floridan Aquifer in the St. Johns River Water Management District and Vicinity, Florida, September 2008

USGS Publications Warehouse

Kinnaman, Sandra L.; Dixon, Joann F.

2009-01-01

This map depicts the potentiometric surface of the Upper Floridan aquifer in the St. Johns River Water Management District and vicinity for September 2008. Potentiometric contours are based on water-level measurements collected at 589 wells during the period September 15-25, near the end of the wet season. Some contours are inferred from previous potentiometric-surface maps with larger well networks. The potentiometric surface of the carbonate Upper Floridan aquifer responds mainly to rainfall, and more locally, to ground-water withdrawals and spring flow. Potentiometric-surface highs generally correspond to topographic highs where the aquifer is recharged. Springs and areas of diffuse upward leakage naturally discharge water from the aquifer and are most prevalent along the St. Johns River. Areas of discharge are reflected by depressions in the potentiometric surface. Ground-water withdrawals locally have lowered the potentiometric surface. Ground water in the Upper Floridan aquifer generally flows from potentiometric highs to potentiometric lows in a direction perpendicular to the contours.

Potentiometric Surface of the Upper Floridan Aquifer in the St. Johns River Water Management District and Vicinity, Florida, September 2007

USGS Publications Warehouse

Kinnaman, Sandra L.; Dixon, Joann F.

2008-01-01

This map depicts the potentiometric surface of the Upper Floridan aquifer in the St. Johns River Water Management District and vicinity for September 2007. Potentiometric contours are based on water-level measurements collected at 554 wells during the period September 15-27, near the end of the wet season. Some contours are inferred from previous potentiometric-surface maps with larger well networks. The potentiometric surface of the carbonate Upper Floridan aquifer responds mainly to rainfall, and more locally, to ground-water withdrawals and spring flow. Potentiometric-surface highs generally correspond to topographic highs where the aquifer is recharged. Springs and areas of diffuse upward leakage naturally discharge water from the aquifer and are most prevalent along the St. Johns River. Areas of discharge are reflected by depressions in the potentiometric surface. Ground-water withdrawals locally have lowered the potentiometric surface. Ground water in the Upper Floridan aquifer generally flows from potentiometric highs to potentiometric lows in a direction perpendicular to the contours.

76 FR 46329 - Notice of Issuance of Renewed Materials License No. SNM-2504; Department of Energy; Fort St...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-02

... Materials License No. SNM-2504; Department of Energy; Fort St. Vrain Independent Spent Fuel Storage... INFORMATION CONTACT: Christopher Staab, Project Manager, Division of Spent Fuel Storage and Transportation... issued renewed Materials License No. SNM-2504 to the Department of Energy (DOE) for the receipt...

Involvement of serotoninergic 5-HT1A/2A, alpha-adrenergic and dopaminergic D1 receptors in St. John's wort-induced prepulse inhibition deficit: a possible role of hyperforin.

PubMed

Tadros, Mariane G; Mohamed, Mohamed R; Youssef, Amal M; Sabry, Gilane M; Sabry, Nagwa A; Khalifa, Amani E

2009-05-16

Prepulse inhibition (PPI) of acoustic startle response is a valuable paradigm for sensorimotor gating processes. Previous research showed that acute administration of St. John's wort extract (500 mg/kg, p.o.) to rats caused significant disruption of PPI while elevating monoamines levels in some brain areas. The cause-effect relationship between extract-induced PPI disruption and augmented monoaminergic transmission was studied using different serotoninergic, adrenergic and dopaminergic antagonists. The effects of hypericin and hyperforin, as the main active constituents of the extract, on PPI response were also tested. PPI disruption was prevented after blocking the serotoninergic 5-HT1A and 5-HT2A, alpha-adrenergic and dopaminergic D1 receptors. Results also demonstrated a significant PPI deficit after acute treatment of rats with hyperforin, and not hypericin. In some conditions manifesting disrupted PPI response, apoptosis coexists. Electrophoresis of DNA isolated from brains of hyperforin-treated animals revealed absence of any abnormal DNA fragmentation patterns. It is concluded that serotoninergic 5-HT1A and 5-HT2A, alpha-adrenergic and dopaminergic D1 receptors are involved in the disruptive effect of St. John's wort extract on PPI response in rats. We can also conclude that hyperforin, and not hypericin, is one of the active ingredients responsible for St. John's wort-induced PPI disruption with no relation to apoptotic processes.

The status of U.S. Virgin Islands' forests, 2004

Treesearch

Thomas J. Brandeis; Sonja N. Oswalt

2007-01-01

Forest covers 21 237 ha of the U.S. Virgin Islands, 61 percent of the total land area. St. John had the highest percentage of forest cover (92 percent), followed by St. Thomas (74 percent), and St. Croix (50 percent). Forest cover has decreased 7 percent from 1994 to 2004, a loss of 1671 ha of forest. Most notably, St. Croix lost 986 ha (11 percent) of subtropical dry...

Roystonea O.F. Cook

Treesearch

Kristina F. Connor; John K. Francis

2008-01-01

There are 2 noteworthy species of Roystonea palms grown in the United States and its territories. Puerto Rico royal palm is native to Puerto Rico and Vieques, St. Croix in the U.S. Virgin Islands, and possibly Tortola in the British Virgin Islands. It has possibly naturalized in the British Virgin Islands and in St. Thomas and St. John in the U.S....

Forests of U.S.Virgin Islands, 2014

Treesearch

Humfredo Marcano-Vega; Joe R. Williamson

2017-01-01

This resource update provides a short overview of the status of forest resources in the U.S. Virgin Islands (St. Croix, St. John, and St. Thomas) based on the third forest inventory funded and conducted by the U.S. Forest Service, Forest Inventory and Analysis (FIA) program of the Southern Research Station and by the International Institute of Tropical...

76 FR 41454 - Caribbean Fishery Management Council; Scoping Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-14

... based on alternative selected in Action 3(a) and time series of landings data as defined in Action 1(a...., Puerto Rico, St. Thomas/St. John, St. Croix) based on the preferred management reference point time series selected by the Council in Actions 1(a) and 2(a). Alternative 2A. Use a mid-point or equidistant...

76 FR 52649 - Golden Triangle Storage, Inc.; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-23

... Triangle Storage, Inc.; Notice of Application On August 5, 2011, Golden Triangle Storage, Inc. (Golden... construct and operate two new salt dome storage caverns at its existing storage site located in Jefferson... Triangle Storage, Inc., 1200 Smith Street, Suite 900, Houston, TX 77002, (832) 397-8642 or John F...

Proceedings of the 2011 Annual Meeting of the Canadian Mathematics Education Study Group = Actes De La Rencontre Annuelle 2011 Du Groupe Canadien D'étude en Didactique Des Mathématiques (35th, St. John's, Newfoundland, Canada, June 10-14, 2011)

ERIC Educational Resources Information Center

Liljedahl, Peter, Ed.; Oesterle, Susan, Ed.; Allan, Darien, Ed.

2012-01-01

This submission contains the Proceedings of the 2011 Annual Meeting of the Canadian Mathematics Education Study Group (CMESG), held at Memorial University of Newfoundland in St. John's, Newfoundland. The CMESG is a group of mathematicians and mathematics educators who meet annually to discuss mathematics education issues at all levels of learning.…

What Roles and Missions for Europe’s Military and Security Forces in the 21st Century?

DTIC Science & Technology

2005-08-01

Studies Dr. John L. Clarke vi Executive Summary Are armies the dinosaurs of the 21st Century, soon to become extinct in the new security environment? What...and 40-year old weapons systems. Dr. John L. Clarke 6 For many reasons , Europe’s armed forces are in a long-term period of decline, and this trend is...in a reasonable period of time and on a high level of interoperability. The capability of carrying out sophisticated operations with a high operational

Application of acoustic velocity meters for gaging discharge of three low-velocity tidal streams in the St. Johns River basin, northeast Florida

USGS Publications Warehouse

Sloat, J.V.; Gain, W.S.

1995-01-01

Index-velocity data collected with acoustic velocity meters, stage data, and cross-sectional area data were used to calculate discharge at three low-velocity, tidal streamflow stations in north-east Florida. Discharge at three streamflow stations was computed as the product of the channel cross-sectional area and the mean velocity as determined from an index velocity measured in the stream using an acoustic velocity meter. The tidal streamlflow stations used in the study were: Six Mile Creek near Picolata, Fla.; Dunns Creek near Satsuma, Fla.; and the St. Johns River at Buffalo Bluff. Cross-sectional areas at the measurement sections ranged from about 3,000 square feet at Six Mile Creek to about 18,500 square feet at St. Johns River at Buffalo Bluff. Physical characteristics for all three streams were similar except for drainage area. The topography primarily is low-relief, swampy terrain; stream velocities ranged from about -2 to 2 feet per second; and the average change in stage was about 1 foot. Instantaneous discharge was measured using a portable acoustic current meter at each of the three streams to develop a relation between the mean velocity in the stream and the index velocity measured by the acoustic velocity meter. Using least-squares linear regression, a simple linear relation between mean velocity and index velocity was determined. Index velocity was the only significant linear predictor of mean velocity for Six Mile Creek and St. Johns River at Buffalo Bluff. For Dunns Creek, both index velocity and stage were used to develop a multiple-linear predictor of mean velocity. Stage-area curves for each stream were developed from bathymetric data. Instantaneous discharge was computed by multiplying results of relations developed for cross-sectional area and mean velocity. Principal sources of error in the estimated discharge are identified as: (1) instrument errors associated with measurement of stage and index velocity, (2) errors in the representation of mean daily stage and index velocity due to natural variability over time and space, and (3) errors in cross-sectional area and mean-velocity ratings based on stage and index velocity. Standard errors for instantaneous discharge for the median cross-sectional area for Six Mile Creek, Dunns Creek, and St. Johns River at Buffalo Bluff were 94,360, and 1,980 cubic feet per second, respectively. Standard errors for mean daily discharge for the median cross-sectional area for Six Mile Creek, Dunns Creek, and St. Johns River at Buffalo Bluff were 25, 65, and 455 cubic feet per second, respectively. Mean daily discharge at the three sites ranged from about -500 to 1,500 cubic feet per second at Six Mile Creek and Dunns Creek and from about -500 to 15,000 cubic feet per second on the St. Johns River at Buffalo Bluff. For periods of high discharge, the AVM index-velocity method tended to produce estimates accurate with 2 to 6 percent. For periods of moderate discharge, errors in discharge may increase to more than 50 percent. At low flows, errors as a percentage of discharge increase toward infinity.

Survival estimates for Florida manatees from the photo-identification of individuals

USGS Publications Warehouse

Langtimm, C.A.; Beck, C.A.; Edwards, H.H.; Fick-Child, K. J.; Ackerman, B.B.; Barton, S.L.; Hartley, W.C.

2004-01-01

We estimated adult survival probabilities for the endangered Florida manatee (Trichechus manatus latirostris) in four regional populations using photo-identification data and open-population capture-recapture statistical models. The mean annual adult survival probability over the most recent 10-yr period of available estimates was as follows: Northwest - 0.956 (SE 0.007), Upper St. Johns River - 0.960 (0.011), Atlantic Coast - 0.937 (0.008), and Southwest - 0.908 (0.019). Estimates of temporal variance independent of sampling error, calculated from the survival estimates, indicated constant survival in the Upper St. Johns River, true temporal variability in the Northwest and Atlantic Coast, and large sampling variability obscuring estimates for the Southwest. Calf and subadult survival probabilities were estimated for the Upper St. Johns River from the only available data for known-aged individuals: 0.810 (95% CI 0.727-0.873) for 1st year calves, 0.915 (0.827-0.960) for 2nd year calves, and 0.969 (0.946-0.982) for manatee 3 yr or older. These estimates of survival probabilities and temporal variance, in conjunction with estimates of reproduction probabilities from photoidentification data can be used to model manatee population dynamics, estimate population growth rates, and provide an integrated measure of regional status.

Mineralogical and geochemical consequences of the long-term presence of CO2 in natural reservoirs: An example from the Springerville-St. Johns Field, Arizona, and New Mexico, U.S.A

USGS Publications Warehouse

Moore, J.; Adams, M.; Allis, R.; Lutz, S.; Rauzi, S.

2005-01-01

The Springerville-St. Johns CO2 field in eastern Arizona and western New Mexico is one of more than a dozen gas fields developed within the Colorado Plateau and Southern Rocky Mountain region. Extensive travertine (CaCO3) deposits record a long history of CO2 migration and leakage to the atmosphere. The oldest travertine deposits may have formed during the initial filling of the CO2 reservoir when groundwaters exsolved CO2 upon reaching the surface. The youngest travertine deposits are associated with springs on the floor of the Little Colorado River valley, but travertine deposition appears to be insignificant today. Older deposits occur up to 325 m above the valley floor. Geologic relationships suggest travertine deposition began in the late Pleistocene after volcanic activity ended at ???0.3 Ma. Most of the CaCO3 could have been derived from dissolution of the underlying limestones and dolomites. Interactions between the reservoir fluids and rocks were observed in core samples from one of the intervals that produced dry gas. These reactions resulted in the dissolution of carbonate cements and detrital feldspars and the formation of dawsonite and kaolinite. Geochemical simulations suggest that the dawsonite could have been deposited when the CO2 fugacity reached 20 bars and that the kaolinite formed as the CO2 fugacity decreased. Corrosion of drill pipe by acidic waters and a pronounced HCO3 anomaly above the CO2 reservoir provide evidence of a continuing flux of CO2 from depth. CO2 storage occurs primarily as dissolved carbonate species and as gas accumulations. Only a small percentage of the CO2 was sequestered in secondary minerals. ?? 2005 Elsevier B.V. All rights reserved.

1. Historic American Buildings Survey John O. Brostrup, Photographer September ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey John O. Brostrup, Photographer September 17, 1936 10:45 A. M. VIEW OF 1315 4th St., S. W., FROM NORTHEAST (front) - Wheat Row, 1315 Fourth Street Southwest, Washington, District of Columbia, DC

Energy Transition Initiative: Island Energy Snapshot - U.S. Virgin Islands (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2015-03-01

This profile provides a snapshot of the energy landscape of the U.S. Virgin Islands (USVI) - St. Thomas, St. John, and St. Croix. The Virgin Islands archipelago makes up the northern portion of the Lesser Antilles and the western island group of the Leeward Islands, forming the border between the Atlantic Ocean and the Caribbean Sea.

Predictive value of serum sST2 in preschool wheezers for development of asthma with high FeNO.

PubMed

Ketelaar, M E; van de Kant, K D; Dijk, F N; Klaassen, E M; Grotenboer, N S; Nawijn, M C; Dompeling, E; Koppelman, G H

2017-11-01

Wheezing is common in childhood. However, current prediction models of pediatric asthma have only modest accuracy. Novel biomarkers and definition of subphenotypes may improve asthma prediction. Interleukin-1-receptor-like-1 (IL1RL1 or ST2) is a well-replicated asthma gene and associates with eosinophilia. We investigated whether serum sST2 predicts asthma and asthma with elevated exhaled NO (FeNO), compared to the commonly used Asthma Prediction Index (API). Using logistic regression modeling, we found that serum sST2 levels in 2-3 years-old wheezers do not predict doctors' diagnosed asthma at age 6 years. Instead, sST2 predicts a subphenotype of asthma characterized by increased levels of FeNO, a marker for eosinophilic airway inflammation. Herein, sST2 improved the predictive value of the API (AUC=0.70, 95% CI 0.56-0.84), but had also significant predictive value on its own (AUC=0.65, 95% CI 0.52-0.79). Our study indicates that sST2 in preschool wheezers has predictive value for the development of eosinophilic airway inflammation in asthmatic children at school age. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

Coral bleaching, hurricane damage, and benthic cover on coral reefs in St. John, U.S. Virgin Islands: A comparison of surveys with the chain transect method and videography

USGS Publications Warehouse

Rogers, C.S.; Miller, J.

2001-01-01

The linear chain transect method and videography were used to quantify the percent cover by corals, macroalgae, gorgonians, other living organisms, and substrate along permanent transects on two fringing reefs off St. John. Both methods were used simultaneously on Lameshur reef in November 1998, and on Newfound reef in March and October 1998. Hurricane Georges passed over St. John in September 1998, and a severe coral bleaching episode began the same month. Both methods gave remarkably similar values for coral cover, while the video method gave consistently higher values for gorgonians and macroalgae. The most dramatic difference was in the quantification of bleaching. At Newfound, the chain method indicated 13.4% (SD = 14.1) of the coral tissues were bleached and the video method, 43.4% (SD = 13.0). Corresponding values at Lameshur were 18.1% (SD = 22.3) and 46.5% (SD = 13.3). Although hurricane damage was conspicuous at Newfound reef, neither method showed significant changes in coral cover or other categories as a result of the storm.

Potentiometric surface of the upper Floridan Aquifer in the St. Johns River Water Management District and vicinity, Florida, September, 2004

USGS Publications Warehouse

Kinnaman, Sandra L.

2005-01-01

Introduction: This map depicts the potentiometric surface of the Upper Floridan aquifer in the St. Johns River Water Management District and vicinity in September 2004. Potentiometric contours are based on water-level measurements collected at 608 wells during the period September 14-October 1, near the end of the wet season. The shapes of some contours have been inferred from previous potentiometric-surface maps with larger well networks. The potentiometric surface of the carbonate Upper Floridan aquifer responds mainly to rainfall, and more locally, to ground-water withdrawals. Potentiometric-surface highs generally correspond to topographic highs where the aquifer is recharged. Springs and areas of diffuse upward leakage naturally discharge water from the aquifer and are most prevalent along the St. Johns River. Areas of discharge are reflected by depressions in the potentiometric surface. Ground-water withdrawals locally have lowered the potentiometric surface. Ground water in the Upper Floridan aquifer generally flows from potentiometric highs to potentiometric lows in a direction perpendicular to the contours.

Potentiometric Surface of the Upper Floridan Aquifer in the St. Johns River Water Management District and Vicinity, Florida, May, 2004

USGS Publications Warehouse

Kinnaman, Sandra L.; Knowles, Leel

2004-01-01

INTRODUCTION This map depicts the potentiometric surface of the Upper Floridan aquifer in the St. Johns River Water Management District and vicinity in May 2001. Potentiometric contours are based on water-level measurements collected at 684 wells during the period May 2 - 30, near the end of the dry season. The shapes of some contours have been inferred from previous potentiometric-surface maps with larger well networks. The potentiometric surface of the carbonate Upper Floridan aquifer responds mainly to rainfall, and more locally, to ground-water withdrawals. Potentiometric-surface highs generally correspond to topographic highs where the aquifer is recharged. Springs and areas of diffuse upward leakage naturally discharge water from the aquifer and are most prevalent along the St. Johns River. Areas of discharge are reflected by depressions in the potentiometric surface. Ground-water withdrawals locally have lowered the potentiometric surface. Ground water in the Upper Floridan aquifer generally flows from potentiometric highs to potentiometric lows in a direction perpendicular to the contours.

How Do We Know They're Getting Better? Assessment for 21st Century Minds, K-8

ERIC Educational Resources Information Center

Barell, John

2012-01-01

How do we measure students inquiry, problem-solving, and critical thinking abilities so that we know they are prepared to meet the challenges of the 21st century? John Barell explains how inquiry leads to problem-solving and provides specific steps for formative assessment that informs instruction of 21st century skills. Included are examples that…

Re-Imagining the 21st Century School Library: From Storage Space to Active Learning Space

ERIC Educational Resources Information Center

Grigsby, Susan K. S.

2015-01-01

As libraries adjust to the needs of the 21st century, there needs to be a different way of thinking in regards to its design. School libraries have traditionally been designed as large rooms for the storage of materials for research and pleasure reading. As more and more districts focus their attention on digital acquisitions, the need for storage…

St. Johns AAFB, St. Johns, Antigua. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A through F.

DTIC Science & Technology

1970-07-13

l t w i f k p t t o r tR (brtbiw Smeutnta. 00 ~ US R F C"hn"Cfbs a /0. R 0 DOCUMENT IDENTIFICATION Appme forpublic s.I~mq DISRIIII)TON STATEMENT...stations using similar reporting practices. HO3URLY OBSERVATIONS are defined as those record or record-special observations recorded at scheduled hourly...have limited use and may be misleading. 2. The second set of tables for each of the above presents the extreme dal nmts ty individual year wA month for

Integrating emergency services in an urban health system.

PubMed

Radloff, D; Blouin, A S; Larsen, L; Kripp, M E

2000-03-01

When planning for growth and management efficiency across urban health systems, economic and market factors present significant service line challenges and opportunities. This article describes the evolutionary integration of emergency services in St John Health System, a large, religious-sponsored health care system located in Detroit, Michigan. Critical business elements, including the System's vision, mission, and economic context, are defined as the framework for site-specific and System-wide planning. The impact of managed care and market changes prompted St John's clinicians and executives to explore how integrating emergency services could create a competitive market advantage.

75 FR 17393 - Intent To Prepare a Draft Environmental Impact Statement for the “Flood Control, Mississippi...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-06

... channel enlargement and improvement in the St. Johns Bayou Basin along the lower 4.5 miles of the St... end of the New Madrid Floodway. The channel enlargement work and both pumping stations are features of...

Educational Rebels in the Nineteen Thirties.

ERIC Educational Resources Information Center

Buchanan, William

1985-01-01

Contrasts the unconventional educational philosophies implemented by Joseph Brewer at Olivet College (MI), John Andrews Rice at Black Mountain College (NC), and Stringfellow Barr at St. John's College (MD). Discusses the educators' personal characteristics, educational methods, and lasting influences. Recounts firsthand experiences as a student at…

The Future Nuclear Landscape

DTIC Science & Technology

2007-04-01

Paul I. Bernstein, John P . Caves, Jr., and John F. Reichart Center for the Study of Weapons of Mass Destruction A p ri l 20 07 Report...participants from the government and private sectors. JohN F. ReiChART Director S TA F F W. SeTh CARUS Deputy Director JohN P . CAveS, JR. Senior...Research Fellow RebeCCA K.C. heRSMAN Senior Research Fellow FoRReST e. WALLeR, JR. Senior Research Fellow RiChARD A. Love Research Fellow Stephen D . Carey

Time to Talk: What You Should Know about 5 Popular Herbs (Evening Primrose Oil, St. John's Wort, Fenugreek, Echinacea, ....

MedlinePlus

... oil , St. John’s wort , fenugreek , echinacea , and aloe vera . Here are 5 tips about these popular herbal ... but some people may have allergic reactions. Aloe Vera. Topical use: A few small studies suggest that ...

Meteor Beliefs Project: Meteoric imagery associated with the death of John Brown in 1859

NASA Astrophysics Data System (ADS)

Drobnock, G. J.; McBeath, A.; Gheorghe, A. D.

2009-12-01

An examination is made of metaphorical meteor imagery used in conjunction with the death of American anti-slavery activist John Brown, who was executed in December 1859. Such imagery continues to be used in this regard into the 21st century.

Expression of interleukin-33 and its receptor ST2 in periapical granulomas and radicular cysts.

PubMed

Velickovic, Milena; Pejnovic, Nada; Petrovic, Renata; Mitrovic, Slobodanka; Jeftic, Ilija; Kanjevac, Tatjana; Lukic, Aleksandra

2016-01-01

Interleukin-33 (IL-33) is a recently identified cytokine belonging to the IL-1 family and ligand for the IL-1 receptor-related protein ST2. IL-33/ST2 signaling plays a critical role in allergy, autoimmunity, and chronic inflammatory disorders, but its role in the pathogenesis of periapical lesions is unknown. We aimed to investigate the expression patterns of IL-33 and ST2 in human periapical lesions. Periapical lesions (n = 36) and healthy periapical tissues (n = 10) were evaluated by immunohistochemistry using antibodies specific for human IL-33 and ST2. Lesion samples were further analyzed by double immunofluorescence to assess IL-33/ST2 co-expression. The numbers of IL-33- and ST2-positive fibroblasts were significantly higher in periapical lesions compared to healthy periapical tissues (both P < 0.05), while the numbers of IL-33- and ST2-positive endothelial cells were similar (both P > 0.05). There were no significant differences in the numbers of IL-33- and ST2-positive fibroblasts and endothelial cells between periapical granulomas and radicular cysts (all P > 0.05). Similarly, numbers of ST2-positive mononuclear cells did not differ between periapical granulomas and radicular cysts (P > 0.05). The majority of epithelial cells in radicular cysts were IL-33 positive, while the small proportion of epithelial cells was ST2 positive. Double immunofluorescence analysis revealed IL-33/ST2 co-expression in fibroblasts and endothelial cells. IL-33 and ST2 are expressed in periapical granulomas and radicular cysts. Increased numbers of IL-33- and ST2-positive fibroblasts in periapical lesions when compared to healthy periapical tissues suggest that IL-33/ST2 signaling may be involved in periapical inflammation and tissue fibrosis. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Used Nuclear Fuel-Storage, Transportation & Disposal Analysis Resource and Data System (UNF-ST&DARDS)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Banerjee, Kaushik; Clarity, Justin B; Cumberland, Riley M

This will be licensed via RSICC. A new, integrated data and analysis system has been designed to simplify and automate the performance of accurate and efficient evaluations for characterizing the input to the overall nuclear waste management system -UNF-Storage, Transportation & Disposal Analysis Resource and Data System (UNF-ST&DARDS). A relational database within UNF-ST&DARDS provides a standard means by which UNF-ST&DARDS can succinctly store and retrieve modeling and simulation (M&S) parameters for specific spent nuclear fuel analysis. A library of various analysis model templates provides the ability to communicate the various set of M&S parameters to the most appropriate M&S application.more » Interactive visualization capabilities facilitate data analysis and results interpretation. UNF-ST&DARDS current analysis capabilities include (1) assembly-specific depletion and decay, (2) and spent nuclear fuel cask-specific criticality and shielding. Currently, UNF-ST&DARDS uses SCALE nuclear analysis code system for performing nuclear analysis.« less

Pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) in stormwater canals and Bayou St. John in New Orleans, Louisiana, USA.

PubMed

Boyd, Glen R; Palmeri, Jordan M; Zhang, Shaoyuan; Grimm, Deborah A

2004-10-15

Samples were collected from two stormwater canals and a recreational urban waterway known as Bayou St. John in New Orleans, Louisiana, USA and analyzed for a range of pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs). Concentrations of 7 PPCPs and EDCs were measured by a method that provides for simultaneous extraction and quantification of the following compounds: clofibric acid, naproxen, ibuprofen, fluoxetine, clorophene, triclosan, bisphenol A. The method also was used as an indicator of the occurrence of estrogenic compounds by targeting estrone and 17beta-estradiol. The two canals (Orleans and London) are used to drain a portion of the city's stormwater directly into the Mississippi River or Lake Pontchartrain. Bayou St. John is located between the two canals and supplied with water from Lake Pontchartrain. Results from the 6-month sampling period indicated the following concentration ranges for the two stormwater canals: naproxen (ND - 145 ng/l), ibuprofen (ND - 674 ng/l), triclosan (ND - 29 ng/l) and bisphenol A (1.9-158 ng/l). Concentrations of these target analytes increased with cumulative rainfall. For bayou waters, only naproxen (2.1-4.8 ng/l) and bisphenol A (0.9-44 ng/l) were detected. Estrone was detected but determined non-quantifiable for multiple sampling events at the 3 sites. None of the other target analytes (clofibric acid, fluoxetine, clorophene, and 17beta-estradiol) were detected above their method detection levels. Results of this study demonstrate the occurrence of PPCPs and EDCs in New Orleans stormwater canals and Bayou St. John. Results also demonstrate the use of this analytical technique as an indicator of non-point source sewage contamination in New Orleans stormwater canals.

Monitoring the coral disease, plague type II, on coral reefs in St. John, U.S. Virgin Islands

USGS Publications Warehouse

Miller, J.; Rogers, C.; Waara, R.

2003-01-01

In July 1997, conspicuous white patches of necrotic tissue and bare skeleton began to appear on scleractinian corals in several bays around St. John, US Virgin Islands. Analysis of diseased coral tissue from five different species confirmed the presence of a Sphingomonas-like bacterium, the pathogen for plague type II. To date, 14 species of hard corals have been affected by plague type II around St. John. This disease was monitored at Haulover and Tektite Reefs at depths of 7-12 meters. The study site at Tektite Reef has >50% cover by scleractinian corals with 90% of hard corals being composed of Montastraea annular is. Monthly surveys at Tektite Reef from December 1997 to May 2001 documented new incidence of disease (bare white patches of skeleton) every month with associated loss of living coral and 90.5% of all disease patches occurred on M. annularis. The frequency of disease within transects ranged from 3 to 58%, and the area of disease patches ranged from 0.25 to 9000 cm2. The average percent cover by the disease within 1 m2 ranged from 0.01% (?? 0.04 SD) to 1.74% (?? 9.08 SD). Photo-monitoring of 28 diseased corals of 9 species begun in September 1997 at Haulover Reef revealed no recovery of diseased portions with all necrotic tissue being overgrown rapidly by turf algae, usually within less than one month. Most coral colonies suffered partial mortality. Very limited recruitment (e.g., of Agaricia spp., Favia spp. and sponges) has been noted on the diseased areas. This coral disease has the potential to cause more loss of live coral on St. John reefs than any other stress to date because it targets the dominant reef building species, M. annularis.

Preserved pharmacological activity of hepatocytes-treated extracts of valerian and St. John's wort.

PubMed

Simmen, Urs; Saladin, Caroline; Kaufmann, Priska; Poddar, Manisha; Wallimann, Christine; Schaffner, Willi

2005-07-01

The two herbal extracts valerian (Valeriana officinalis L.) and St. John's wort (Hypericum perforatum L.) were studied for their metabolic changes upon incubation with freshly prepared rat hepatocytes and subsequently analysed phytochemically as well as pharmacologically in vitro. Quantitative HPLC analysis of valerian extracts revealed considerable metabolic activities with regard to sesquiterpenes and iridoids. The amount of acetoxyvalerenic acid decreased 9-fold, while that of hydroxyvalerenic acid correspondingly increased 9-fold due to O-deacetylation. The valepotriates didrovaltrate, isovaltrate and valtrate decreased 2-, 18- and 16-fold, respectively. However, the binding affinities of the incubated extracts to the benzodiazepine and picrotoxin binding site of the GABA (A) receptor were quite similar to those of the non-incubated extracts. Neither valerenic acids nor valepotriates exhibited any significant effect on the two binding sites when tested as single compounds. Therefore, either other constituents represent the active ones or multiple compounds are necessary for the observed inhibitory and allosteric effects at the GABA (A) receptor. Extracts of St. John's wort were less potently metabolised than valerian. The amount of pseudohypericin and the main flavonoids (hyperoside, rutin, isoquercitrin, quercitrin, quercetin and I3,II8-biapigenin) slightly decreased during the 4-h incubation period. Both the antagonist effect at the corticotropin-releasing factor (CRF) type 1 receptor and the binding inhibition at the 5-HT transporter were attenuated during the metabolic treatment. The reduced antagonist effect correlates with the decreasing amount of pseudohypericin known to be a CRF (1) receptor antagonist. In conclusion, the incubation of plant extracts with freshly prepared rat hepatocytes represents a useful approach to study the pharmacological action of metabolised plant extracts. The consistent pharmacological activity of both valerian and St. John's wort is concordant with the known clinical efficacy of pharmacological activities.

8. Historic American Buildings Survey PHOTOCOPY ORIGINAL ARCHITECTS' DRAWING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Historic American Buildings Survey PHOTOCOPY -- ORIGINAL ARCHITECTS' DRAWING IN INK ON LINEN (ABOUT 3'-7'x2'-7 1/2') (C. 1889). ORIGINAL IN THE COLLECTION OF THE PRESBYTERIAN CHURCH, ST. AUGUSTINE, FLORIDA - Flagler Memorial Presbyterian Church, Valencia & Sevilla Streets, Saint Augustine, St. Johns County, FL

Bioactive xanthones from the roots of Hypericum perforatum (common St John's Wort)

USDA-ARS?s Scientific Manuscript database

In contemporary western alternative medicine, extracts of the inflorescences and upper stem leaves of Hypericum perforatum L. (common St. John’s Wort; Clusiaceae) are taken orally for the treatment of mild to moderate depression and applied topically to promote wound-healing. Numerous researchers h...

12. HISTORICAL VIEW OF FRONT ENTRANCE, BEFORE ADDITION OF SHELTERED ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. HISTORICAL VIEW OF FRONT ENTRANCE, BEFORE ADDITION OF SHELTERED PORCH, SOUTH ELEVATION, 1907. Photocopied from Henry Pleasants's book, History of Old St. David's Church, published in 1915 by John C. Winston Co. - St. David's Church (Episcopal), Valley Forge Road (Newtown Township), Wayne, Delaware County, PA

13. HISTORICAL VIEW OF NAVE AND ALTAR, LOOKING NORTH, 1907. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. HISTORICAL VIEW OF NAVE AND ALTAR, LOOKING NORTH, 1907. (Altar was at east end originally). Photocopied from Henry Pleasants's book, History of Old St. David's Church, published in 1915 by John C. Winston Co. - St. David's Church (Episcopal), Valley Forge Road (Newtown Township), Wayne, Delaware County, PA

7 CFR 319.77-3 - Gypsy moth infested areas in Canada.

Code of Federal Regulations, 2010 CFR

2010-01-01

... that includes the following parishes: Campobello Island, Dumbarton, Dufferin, Grand Manan Island, St... south and east of the Scotch Lake Road beginning in the west at Bear Island on the St. John River and..., Bright Additional, Cobden, Denis, Garden River First Nation, Indian Reserve #7, Johnson, Korah, Laird...

7 CFR 319.77-3 - Gypsy moth infested areas in Canada.

Code of Federal Regulations, 2011 CFR

2011-01-01

... that includes the following parishes: Campobello Island, Dumbarton, Dufferin, Grand Manan Island, St... south and east of the Scotch Lake Road beginning in the west at Bear Island on the St. John River and..., Bright Additional, Cobden, Denis, Garden River First Nation, Indian Reserve #7, Johnson, Korah, Laird...

7 CFR 319.77-3 - Gypsy moth infested areas in Canada.

Code of Federal Regulations, 2012 CFR

2012-01-01

... that includes the following parishes: Campobello Island, Dumbarton, Dufferin, Grand Manan Island, St... south and east of the Scotch Lake Road beginning in the west at Bear Island on the St. John River and..., Bright Additional, Cobden, Denis, Garden River First Nation, Indian Reserve #7, Johnson, Korah, Laird...

7 CFR 319.77-3 - Gypsy moth infested areas in Canada.

Code of Federal Regulations, 2014 CFR

2014-01-01

... that includes the following parishes: Campobello Island, Dumbarton, Dufferin, Grand Manan Island, St... south and east of the Scotch Lake Road beginning in the west at Bear Island on the St. John River and..., Bright Additional, Cobden, Denis, Garden River First Nation, Indian Reserve #7, Johnson, Korah, Laird...

7 CFR 319.77-3 - Gypsy moth infested areas in Canada.

Code of Federal Regulations, 2013 CFR

2013-01-01

... that includes the following parishes: Campobello Island, Dumbarton, Dufferin, Grand Manan Island, St... south and east of the Scotch Lake Road beginning in the west at Bear Island on the St. John River and..., Bright Additional, Cobden, Denis, Garden River First Nation, Indian Reserve #7, Johnson, Korah, Laird...

St. Johns County, St. Augustine Inlet, FL, Report 1: Historical Analysis and Sediment Budget

DTIC Science & Technology

2012-08-01

Anastasia Island ........................................................ 26  4.5  Alongshore region of influence of the inlet...profile T-129 from 1984 to 2010. ....................................................... 15  Figure 16. Ebb shoal bathymetry, Vilano and Anastasia Islands...2007. ............................................. 17  Figure 17. Ebb shoal bathymetry, Vilano and Anastasia Islands, 2008

John Dewey in the 21st Century

ERIC Educational Resources Information Center

Williams, Morgan K.

2017-01-01

John Dewey was a pragmatist, progressivist, educator, philosopher, and social reformer (Gutek, 2014). Dewey's various roles greatly impacted education, and he was perhaps one of the most influential educational philosophers known to date (Theobald, 2009). Dewey's influence on education was evident in his theory about social learning; he believed…

78 FR 2689 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-14

... Rapides Parish Guaranty Bank, Park Avenue Branch, 403 Bolton Ave., Alexandria, 12001206 MISSOURI Howard...., Front & Beech Sts., Berea, 12001210 Carroll, John, University North Quad Historic District, 1 John Carroll Blvd., University Heights, 12001211 East Ohio Building, The, 1717 E. 9th St., Cleveland, 12001212...

Water resources of St. John the Baptist Parish, Louisiana

USGS Publications Warehouse

White, Vincent E.; Prakken, Lawrence B.; Fendick, Robert B.

2015-01-01

Information concerning the availability, use, and quality of water in St. John the Baptist Parish, Louisiana, is critical for proper water-supply management. The purpose of this fact sheet is to present information that can be used by water managers, parish residents, and others for stewardship of this vital resource. Information on the availability, past and current use, use trends, and water quality from groundwater and surface-water sources in the parish is presented. Previously published reports and data stored in the U.S. Geological Survey’s National Water Information System (http://waterdata.usgs.gov/nwis) are the primary sources of the information presented here.

Potentiometric Surface of the Upper Floridan Aquifer in the St. Johns River Water Management District and Vicinity, Florida, May 2007

USGS Publications Warehouse

Kinnaman, Sandra L.; Dixon, Joann F.

2007-01-01

Introduction This map depicts the potentiometric surface of the Upper Floridan aquifer in the St. Johns River Water Management District and vicinity for May 2007. Potentiometric contours are based on water-level measurements collected at 566 wells during the period May 4-June 11 near the end of the dry season, however most of the water level data for this map were collected by the U.S. Geological Survey during the period May 21-25, 2007. Some contours are inferred from previous potentiometric-surface maps with larger well networks. The potentiometric surface of the carbonate Upper Floridan aquifer responds mainly to rainfall, and more locally, to ground-water withdrawals and spring flow. Potentiometric-surface highs generally correspond to topographic highs where the aquifer is recharged. Springs and areas of diffuse upward leakage naturally discharge water from the aquifer and are most prevalent along the St. Johns River. Areas of discharge are reflected by depressions in the potentiometric surface. Ground-water withdrawals locally have lowered the potentiometric surface. Ground water in the Upper Floridan aquifer generally flows from potentiometric highs to potentiometric lows in a direction perpendicular to the contours.

Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects.

PubMed

Dresser, George K; Schwarz, Ute I; Wilkinson, Grant R; Kim, Richard B

2003-01-01

Many drugs are cosubstrates of cytochrome P450 (CYP) 3A and MDR1; furthermore, their disposition is markedly affected by pretreatment with inducing agents, including St John's wort. Such drug interactions reflect induction of both proteins through a common mechanism involving the steroid X receptor/pregnane X receptor. However, the relative contributions of enhanced metabolism and efflux transport to the overall induction process are unknown. The effects of 12 days' pretreatment with St John's wort on the disposition of selected in vivo probe drugs were determined in 21 young healthy subjects. Midazolam after oral and intravenous administration was used to assess CYP3A activity in both the intestinal epithelium and the liver, whereas the disposition of fexofenadine after an oral dose was assumed to be a measure of MDR1 function, and the oral plasma concentration-time profile of cyclosporine (INN, ciclosporin) was considered to reflect both CYP3A and MDR1 activities. St John's wort markedly affected the plasma concentration-time profiles of all of the drugs, with associated increases in their clearance. With midazolam, the enhancement was considerably less after intravenous administration (approximately 1.5-fold) than after oral administration (approximately 2.7-fold), and estimated intestinal and hepatic extraction ratios were higher by approximately 1.2- to 1.4-fold. By contrast, the oral clearances of fexofenadine and cyclosporine were equally increased by approximately 1.6-fold and 1.9-fold, respectively; these changes were both statistically less than for midazolam's oral clearance and greater than its estimated intestinal extraction. Although the disposition of all 3 drugs was altered by St John's wort, the extent of induction measured by oral clearance was different with CYP3A activity (midazolam), apparently increasing more than MDR1 function (fexofenadine), whereas with cyclosporine the change in oral clearance appeared to be more closely associated with the increase in MDR1 rather than CYP3A, despite the fact that both proteins are importantly involved in its disposition. These discordances indicate that, although a common molecular mechanism may be involved, the quantitative aspects of induction are complex and depend on the particular drug and the relative contributions of CYP3A and MDR1 in its disposition.

An ECG ambulatory system with mobile embedded architecture for ST-segment analysis.

PubMed

Miranda-Cid, Alejandro; Alvarado-Serrano, Carlos

2010-01-01

A prototype of a ECG ambulatory system for long term monitoring of ST segment of 3 leads, low power, portability and data storage in solid state memory cards has been developed. The solution presented is based in a mobile embedded architecture of a portable entertainment device used as a tool for storage and processing of bioelectric signals, and a mid-range RISC microcontroller, PIC 16F877, which performs the digitalization and transmission of ECG. The ECG amplifier stage is a low power, unipolar voltage and presents minimal distortion of the phase response of high pass filter in the ST segment. We developed an algorithm that manages access to files through an implementation for FAT32, and the ECG display on the device screen. The records are stored in TXT format for further processing. After the acquisition, the system implemented works as a standard USB mass storage device.

U.S. Virgin Islands’ Forests, 2009

Treesearch

Thomas J. Brandeis; Jeffery A. Turner

2013-01-01

Forest area on the U.S. Virgin Islands held steady, or decreased slightly, from 2004 (46,564 acres) to 2009 (45,163 acres). There were 26,179 acres of forest on St. Croix (49.6 percent forested), 10,343 acres of forest on St. John (85.5 percent forested) and 8,641 acres of forest on St. Thomas (50.1 percent forested). We estimate there to be 85.1 million trees in the U...

Dielectric and Ferroelectric Properties of SrTiO3-Bi0.5Na0.5TiO3-BaAl0.5Nb0.5O3 Lead-Free Ceramics for High-Energy-Storage Applications.

PubMed

Yan, Fei; Yang, Haibo; Lin, Ying; Wang, Tong

2017-11-06

Pulsed capacitors require high-recoverable energy-storage density (W rec ) and high energy-storage efficiency (η), which can be realized through the selection and adjustment of the composition. In this work, (1 - x)SrTiO 3 -x(0.95Bi 0.5 Na 0.5 TiO 3 -0.05BaAl 0.5 Nb 0.5 O 3 ) [(1 - x)ST-x(BNT-BAN)] ceramics were successfully prepared via the pressureless solid-state reaction method. The dielectric constant increases gradually with the introduction of BNT-BAN and obtains a maximum value of 3430 with the composition of 0.4ST-0.6(BNT-BAN) at 100 Hz, which is 10.39 times higher than that of the pure ST sample (∼330). Dispersive relaxor behaviors and ferroelectric performances can be enhanced with the introduction of BNT-BAN. The composition of 0.5ST-0.5(BNT-BAN) exhibits a high W rec of 1.89 J/cm 3 as well as a high η of 77%. Therefore, the (1 - x)ST-x(BNT-BAN) systems are candidate materials for pulsed capacitor applications.

Information Operations and Warfare: Fundamental Challenges for the 21st Century

DTIC Science & Technology

1997-05-01

Perritt, Jr., Access To The National Information Infrastructure, 30 WAKE FOREST L. REV. 51 (1995); John I. Alger, Declaring Information War, JANE’S...Sought For Info Warfare, COMPUTERWORLD, Jun. 5, 1995, at 55 [hereinafter New Laws]; John Arquilla & David Ronfeldt, Cyberwat is Coming!, COMPARATIVE...at 82. See also John T. Correll, Signs of a Revolution, AIR FORCE MAG., Aug. 1995, at 2 ("Over the years, there have been periodic innovations

75 FR 61478 - D'Lo Gas Storage, LLC; Notice of Petition

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-05

... Storage, LLC; Notice of Petition September 24, 2010. Take notice that on September 21, 2010, D'Lo Gas Storage, LLC (Petitioner), 1002 East St. Mary Boulevard, Lafayette, Louisiana 70503, filed in Docket No... determine feasibility of developing the underlying salt dome formation for natural gas storage, all as more...

75 FR 21288 - Henry Gas Storage LLC; Notice of Application

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-23

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP10-125-000] Henry Gas Storage LLC; Notice of Application April 16, 2010. Take notice that on April 5, 2010, Henry Gas Storage... developing the Cote Blanche Island salt dome for natural gas storage in St. Mary Parish, Louisiana, all as...

New records of fish parasitic isopods of the gill-attaching genus Mothocya Costa, in Hope, 1851 from the Virgin Islands, Caribbean, with description of a new species.

PubMed

Hadfield, Kerry A; Sikkel, Paul C; Smit, Nico J

2014-01-01

Two species of Mothocya Costa, in Hope, 1851 are reported from the Virgin Islands. Mothocya xenobranchia Bruce, 1986 was collected from St. John Island from the gills of the Atlantic needlefish, Strongylura marina, which is a new locality record and also confirms a previously uncertain host identity. Mothocya bertlucy sp. n. is described from St. Thomas, St John and Guana Islands, from the gills of the redlip blenny, Ophioblennius macclurei, the first record of a blenny as host for any Mothocya. The distinguishing characters of Mothocya bertlucy sp. n. include its small size (< 9 mm) and eyes, the slender pleotelson with a narrowly rounded caudomedial point, extended uropod peduncle and uropods which do not extend past the pleotelson posterior margin, and the narrow pleon which is only slightly overlapped by pereonite 7.

New records of fish parasitic isopods of the gill-attaching genus Mothocya Costa, in Hope, 1851 from the Virgin Islands, Caribbean, with description of a new species

PubMed Central

Hadfield, Kerry A.; Sikkel, Paul C.; Smit, Nico J.

2014-01-01

Abstract Two species of Mothocya Costa, in Hope, 1851 are reported from the Virgin Islands. Mothocya xenobranchia Bruce, 1986 was collected from St. John Island from the gills of the Atlantic needlefish, Strongylura marina, which is a new locality record and also confirms a previously uncertain host identity. Mothocya bertlucy sp. n. is described from St. Thomas, St John and Guana Islands, from the gills of the redlip blenny, Ophioblennius macclurei, the first record of a blenny as host for any Mothocya. The distinguishing characters of Mothocya bertlucy sp. n. include its small size (< 9 mm) and eyes, the slender pleotelson with a narrowly rounded caudomedial point, extended uropod peduncle and uropods which do not extend past the pleotelson posterior margin, and the narrow pleon which is only slightly overlapped by pereonite 7. PMID:25317058

Information Technology Challenges Facing the Strategic Leaders of Homeland Security in the 21st Century

DTIC Science & Technology

2004-05-03

A special thanks to all of these folks (Glenn Starnes, Lee Gutierrez, Bill Rapp, Joel Hillison, Carlos Gomez, Steve Fraunfelter, Janie Hopkins, Dave ...DiClemente, Joe Nunez, John Bonin , and Steve Nerheim). viii INFORMATION TECHNOLOGY CHALLENGES FACING THE STRATEGIC LEADERS OF HOMELAND SECURITY IN THE 21ST

18. Historic American Buildings Survey PHOTOCOPY OF SKETCH BY FREDERIK ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

18. Historic American Buildings Survey PHOTOCOPY OF SKETCH BY FREDERIK GJESSING USED TO ILLUSTRATE HIS ARTICLE 'OBSERVATIONS ON THE OLDEST HOUSE, ST. AUGUSTINE,' (p.111) IN EVOLUTION OF THE OLDEST HOUSE TALLAHASSEE, FLORIDA: DEPARTMENT FLORIDA STATE UNIVERSITY, 1962 - Gonzalez-Alvarez House, 14 Saint Francis Street, Saint Augustine, St. Johns County, FL

75 FR 77901 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-14

..., 10001109 NORTH CAROLINA Franklin County Perry School, 2266 Laurel Mill-Centerville Rd, Centerville... Penn Rd, N State St, Glascock St, and Madison Rd, Raleigh, 10001112 Longview Gardens Historic District... County Rogers, John R., High School, 1622 E Wellesley Ave, Spokane, 10001104 [FR Doc. 2010-31252 Filed 12...

Reforming US National Security for the 21st Century

DTIC Science & Technology

2008-04-23

of the President of the CSIS, John Hambre . In his June 19, 2007 he testified to the HASC that “legislation [forcing] the Defense Department to...January 2008) 19. 13 Excerpt from the testimony of John Hambre as found in HASC, Panel on Roles and Missions: Initial Perspectives, 22. 14 Excerpt from

Prevention of complications in glycogen storage disease type Ia with optimization of metabolic control.

PubMed

Dambska, M; Labrador, E B; Kuo, C L; Weinstein, D A

2017-08-01

Prior to 1971, type Ia glycogen storage disease was marked by life-threatening hypoglycemia, lactic acidosis, severe failure to thrive, and developmental delay. With the introduction of continuous feeds in the 1970s and cornstarch in the 1980s, the prognosis improved, but complications almost universally developed. Changes in the management of type Ia glycogen storage disease have resulted in improved metabolic control, and this manuscript reviews the increasing evidence that complications can be delayed or prevented with optimal metabolic control as previously was seen in diabetes. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Hyperforin inhibits cell proliferation and differentiation in mouse embryonic stem cells.

PubMed

Nakamura, K; Aizawa, K; Yamauchi, J; Tanoue, A

2013-10-01

Hyperforin, a phloroglucinol derivative of St. John's Wort, has been identified as the major molecule responsible for this plant's products anti-depressant effects. It can be expected that exposure to St. John's Wort during pregnancy occurs with some frequency although embryotoxic or teratogenic effects of St. John's Wort and hyperforin have not yet been experimentally examined in detail. In this study, to determine any embryotoxic effects of hyperforin, we have attempted to determine whether hyperforin affects growth and survival processes of employing mouse embryonic stem (mES) cells (representing embryonic tissue) and fibroblasts (representing adult tissues). We used a modified embryonic stem cell test, which has been validated as an in vitro developmental toxicity protocol, mES cells, to assess embryotoxic potential of chemicals under investigation. We have identified that high concentrations of hyperforin inhibited mouse ES cell population growth and induced apoptosis in fibroblasts. Under our cell culture conditions, ES cells mainly differentiated into cardiomyocytes, although various other cell types were also produced. In this condition, hyperforin affected ES cell differentiation into cardiomyocytes in a dose-dependent manner. Analysis of tissue-specific marker expression also revealed that hyperforin at high concentrations partially inhibited ES cell differentiation into mesodermal and endodermal lineages. Hyperforin is currently used in the clinic as a safe and effective antidepressant. Our data indicate that at typical dosages it has only a low risk of embryotoxicity; ingestion of large amounts of hyperforin by pregnant women, however, may pose embryotoxic and teratogenic risks. © 2013 John Wiley & Sons Ltd.

History of the Air Corps Tactical School 1920-1940

DTIC Science & Technology

1998-01-01

1st Lt. Air Corps SHUFELT, James V. V. Captain Cavalry STRATEMEYER, George E. Major Air Corps SZILAGYI , Nicholas Captain Infantry TYNDALL, Frank B...Air Corps WALLACE , William J. Captain U.S. Marine Corps WEDDINGTON, Harry Captain Air Corps WEIKERT, John M. 1st Lt. Air Corps WHEELER, Walter L. 1st...M. Captain Air Corps SMITH, Joseph Captain Air Corps SMITH, Wallace G. Major Air Corps STOWELL, James S. Captain Air Corps TAYLOR, Yantis H. Captain

Association of sedentary time and physical activity with pain, fatigue, and impact of fibromyalgia: the al-Ándalus study.

PubMed

Segura-Jiménez, V; Borges-Cosic, M; Soriano-Maldonado, A; Estévez-López, F; Álvarez-Gallardo, I C; Herrador-Colmenero, M; Delgado-Fernández, M; Ruiz, J R

2017-01-01

We examined the association of objectively measured sedentary time (ST) and physical activity (PA) levels with pain, fatigue, and the impact of the disease in women with fibromyalgia. Four hundred and nineteen (mean age ± SD = 51.7 ± 7.6 years old) women with fibromyalgia participated. ST and PA levels (light, moderate, and moderate-to-vigorous [MVPA]) were measured with triaxial accelerometry. We assessed experimental pain with algometry and clinical pain, fatigue, and impact of fibromyalgia with a number of questionnaires. The association of ST and light PA with most of the pain- and fatigue-related outcomes and impact of fibromyalgia (all, P ≤ 0.019) was independent of moderate and vigorous PA. Furthermore, the association of vigorous PA with general and physical fatigue was independent of ST and light and moderate PA (all, P < 0.001). In conclusion, lower levels of ST or higher levels of light PA are associated with lower pain, fatigue, and the overall impact of the disease independent of moderate and vigorous PA in women with fibromyalgia. Interestingly, higher vigorous PA is independently associated with lower general and physical fatigue. These results are significant for future ST and PA intervention studies in this population. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Effect of sweetener combination and storage temperature on physicochemical properties of sucrose free white chocolate.

PubMed

Rodriguez Furlán, Laura T; Baracco, Yanina; Lecot, Javier; Zaritzky, Noemi; Campderrós, Mercedes E

2017-08-15

The influence of a combination of sweeteners (Stevia (St) and sucralose (Su)) and storage temperature on thermal properties, microstructure, water content, texture and Bloom of sucrose free white chocolate was investigated. A strong relationship between the microstructure and the highest percentage of Bloom was observed. The samples with 100%Su and 50%S+50%Su presented microstructures with channels through which solids and fat could more easily spread to the surface, increasing the fat and sugar Bloom formation. However, 50%St+50%Su and 75%St+25%Su samples showed a minimum Bloom formation, probably due to its dense microstructure with no void spaces. The differential scanning calorimetry studies demonstrated that the samples containing 100%St and 75%St+25%Su showed the smallest decrease of melting enthalpy with increasing temperature. Besides, non-isothermal crystallization kinetics was studied by applying Avrami model. The sample 75%St+25%Su presented the highest values of activation energy showing the greatest stability in the temperature range studied (7°C-30°C). Copyright © 2017 Elsevier Ltd. All rights reserved.

Phase 1 Environmental Baseline Survey, The Landings at Nellis Housing Area, Parcel H, Nellis Air Force Base, Nevada

DTIC Science & Technology

2011-06-01

Pulido, Environmental Restoration Program Manger, Nellis AFB, Henry Rodriguez , Toxics Program Manger, Nellis AFB, John Roe, Water Quality Program...TESTING February 14, 2011 Hunt Building Company Inc. Mr. John Leidolf 4401 N Mesa El Paso, TX 79902 Re: Clearance Letter for Parcel H, 1 & 2...Prepared for: Mr. John Leidolf Hunt Building Company, LTD. 4401 N. Mesa St. El Paso, TX 79912 Project: Nellis Air Force Base Salmon Street

Effect of eluent pH on the HPLC-UV analysis of hyperforin from St. John's Wort (Hypericum perforatum L.).

PubMed

Fourneron, Jean-Dominique; Naït-Si, Youssef

2006-01-01

The effect of the pH of the mobile phase in HPLC analysis of hyperforin was investigated. Working with an extract of St. John's Wort (Hypericum perforatum L.) that is rich in hyperforin, significant differences were observed in conventional chromatograms depending on whether the mobile phase was acidic or alkaline. Chromatogram changes were paralleled by changes in the UV spectrum of the hyperforin peak. The structural changes in hyperforin occur in the chromatographic column itself, as has been confirmed by UV spectroscopy performed on a sample of purified hyperforin, which showed that the UV spectrum is indeed dependent on the pH of its environment.

Hyperforin: To Be or Not to Be an Activator of TRPC(6).

PubMed

Friedland, Kristina; Harteneck, Christian

2015-01-01

Meantime, it is well accepted that hyperforin, the chemical instable phloroglucinol derivative of Hypericum perforatum, St. John's wort, is the pharmacophore of St. John's wort extracts. With the decline of this scientific discussion, another controversial aspect has been arisen, the question regarding the underlying mechanism leading to the pharmacological profile of the plant extract used in therapy of depression. We will summarize the different concepts described for hyperforin's antidepressive activity. Starting with unspecific protein-independent mechanisms due to changes in pH, we will summarize data of protein-based concepts beginning with concepts based on involvement of a variety of proteins and will finally present concepts based on the modulation of a single protein.

VIEW NORTH OF PRESTRESS TRACK CENTERHEMP STORAGE BUILDING 77 (1920) ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW NORTH OF PRE-STRESS TRACK CENTER-HEMP STORAGE BUILDING 77 (1920) ROPE WAREHOUSE 43 (1941) BEHIND IT STORAGE SHED 44 (1953) IN FRONT - John A. Roebling's Sons Company & American Steel & Wire Company, South Broad, Clark, Elmer, Mott & Hudson Streets, Trenton, Mercer County, NJ

11. HISTORICAL VIEW OF CHURCH WITH ENCLOSED STAIRWAY ADDITION, LOOKING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. HISTORICAL VIEW OF CHURCH WITH ENCLOSED STAIRWAY ADDITION, LOOKING NORTHWEST, 1850s. Photocopied from Henry Pleasants's book, History of Old St. David's Church, published in 1915 by John C. Winston Co. It is perhaps the earliest photograph of the church. - St. David's Church (Episcopal), Valley Forge Road (Newtown Township), Wayne, Delaware County, PA

75 FR 74079 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-30

..., 330 Marshall St, Lansing, 10001025 Muskegon County Lewis, John C. and Augusta Covell, House, 324 S... Archeological Site 34Jf109, Address Restricted, Belleville, 10001014 Kay County Downtown Ponca City Historic... resource: OREGON Multnomah County Brown, Capt. John A., House, 525 NW 19th Ave, Portland, 71001086 [FR Doc...

Modal Analysis and Testing of Missile Systems

DTIC Science & Technology

1988-12-01

TECHNICAL REPORT -Rb-ST-eS MODAL ANALY AND TESMG OF MISSU E SYSTEMS Lfl 0 N Larry C. Mixon John A4 Schaeffel , Jr. Peter L. Green ,I iLT Roque L...Include Stcurty Claz ficaDin) MODAL ANALYSIS AND TESTING OF MISSILE SYSTEMS 12. PERSONAL AUTHOR(S) Larry C. Mixon, John A. Schaeffel , Jr., Peter L. Green

Innovations in Military Organizations

DTIC Science & Technology

1990-12-01

Although there are 14 many generalizations made by some researchers but they are not certain rules. According to John Naisbitt, author of Megatrends ...adverse and economic biological structural and changes. attitude changes 10-15 Infrastructure Industrial and Long-term systems institutional health...NAISBITT, John, Megatrends , 1st ed., 1983. 8. SUMANTH, D. J., Challenges and Opportunities in Managing Technology, 1988. 9. UTTERBACK, James

2005 21st National Logistics Conference and Exhibition

DTIC Science & Technology

2005-03-03

Logistics Transformation ... Achieving Knowledge-Enabled Logistics Panel: Sustained Materiel Readiness, by Mr. David V. Pauling , Assistant Deputy Under... John Erb, Deputy Director for Strategic Logistics, The Joint Staff Desired Operational Logistics Capabilities, by COL Dave Mintus, USA, NORAD-US...KBR Government Operations Session 8: Operational Logistics Information Technology Government Chair: Mr. John J. Erb, Deputy Director for Strategic

Optimization of Ebb Shoal Mining and Beach Nourishment at St. Johns County, St. Augustine Inlet, Florida, Report 3

DTIC Science & Technology

2012-08-01

Figure 6). Over the latter time period, from 1999 to 2007, Anastasia State Park experienced significant accretion where the region directly to the south...cu yd/year. However, a known reversal in net transport exists from the northern tip of Anastasia Island down to St. Augustine Beach, and the...connectivity. Therefore, the inlet left- bypassing location was set to the first adjacent cell. Downdrift of the inlet (to the right), the beach at Anastasia

Phase 1 Environmental Baseline Survey Nellis Terrace Housing Area, Parcel E-1, Nellis Air Force Base, Nevada

DTIC Science & Technology

2010-03-01

Program Manger, Nellis AFB, Henry Rodriguez , Toxics Program Manger, Nellis AFB, John Roe, Water Quality Program Manger, Nellis AFB, Charles...Hunt Building Company, LTD " 440 1 N. Mesa St. El Paso, TX 79912 Project: Nellis Air Force Base 174 Swaab Blvd. & 10 Jones Street Las Vegas...Company, Ltd 4401 N. Mesa St. El Paso, TX 79912 Project: Chlordane Soil Sampling Nellis Air Force Base 174 Swaab Blvd. & 10 Jones St. Las Vegas

Corps of Engineers Structural Engineering Conference Held in St. Johns County, Florida on 8-12 July 1991. Volume 1

DTIC Science & Technology

1992-12-01

ville, surveying personnel and surveyors at fects from the concrete heat of hydration, the Engineering Technology Laboratory and solar radiation, and...CESEC91 Schuitz 317 LA-J 4 zz C.I.A 4 -r Lfl- ST. PEER ST 0’ Uz M 0; ~ w z d L 0l Fra lwý CLu V)C,0 W V) -j V- u0) 318r Bctjt CEE9 A304MC. PANAlS - ELE

Proceedings of the High Energy Density Matter (HEDM) Contractors’ Conference Held 1-3 June 1997 in Chantilly, VA.

DTIC Science & Technology

1998-03-01

David R. Yarkony, Johns Hopkins University 3:00 - 3:30 Break 3:30 - 4:00 Calorimetric Measurements of O Atom Recombination Dr. Peter Taborek and...University Stillwater, OK 74078 405-744-5174 405-744-6007 dlt@osuunx.ucc.okstate.edu Dr. David R. Yarkony Dept. of Chemistry Johns Hopkins...Chemistry Johns Hopkins University 3400 N. Charles St., Remsen Baltimore, MD 21218 410-516-4669 410-516-8420 yangxin@jhunix.hcf.jhu.edu Prof. David

Paradise Threatened: Land Use and Erosion on St. John, US Virgin Islands

PubMed

Macdonald; Anderson; Dietrich

1997-11-01

/ Rapid development and the concomitant increases in erosion and sedimentation are believed to threaten the reefs and other marine resources that are a primary attraction of St. John and Virgin Islands National Park. Average annual sediment yields from undeveloped areas were estimated from a sediment pond and a mangrove swamp as less than 20 and less than 40 t/km2/yr, respectively. Geomorphic evidence indicates that plantation agriculture during the 18th and 19th centuries did not cause severe erosion. Since about 1950 there has been rapid growth in roads and development due to increasing tourism and second-home development. Our field investigations identified the approximately 50 km of unpaved roads as the primary source of anthropogenic sediment. Field measurements of the road network in two catchments led to the development of a vector-based GIS model to predict road surface erosion and sediment delivery. We estimate that road erosion has caused at least a fourfold increase in island-wide sediment yields and that current sedimentation rates are unprecedented. Paving the dirt roads and implementing standard sediment control practices can greatly reduce current sediment yields and possible adverse effects on the marine ecosystems surrounding St. John.KEY WORDS: Erosion; Sediment yield; Roads; Dry tropics; Development

Quantitative analysis of the major constituents of St John's wort with HPLC-ESI-MS.

PubMed

Chandrasekera, Dhammitha H; Welham, Kevin J; Ashton, David; Middleton, Richard; Heinrich, Michael

2005-12-01

A method was developed to profile the major constituents of St John's wort extracts using high-performance liquid chromatography-electrospray mass spectrometry (HPLC-ESI-MS). The objective was to simultaneously separate, identify and quantify hyperforin, hypericin, pseudohypericin, rutin, hyperoside, isoquercetrin, quercitrin and chlorogenic acid using HPLC-MS. Quantification was performed using an external standardisation method with reference standards. The method consisted of two protocols: one for the analysis of flavonoids and glycosides and the other for the analysis of the more lipophilic hypericins and hyperforin. Both protocols used a reverse phase Luna phenyl hexyl column. The separation of the flavonoids and glycosides was achieved within 35 min and that of the hypericins and hyperforin within 9 min. The linear response range in ESI-MS was established for each compound and all had linear regression coefficient values greater than 0.97. Both protocols proved to be very specific for the constituents analysed. MS analysis showed no other signals within the analyte peaks. The method was robust and applicable to alcoholic tinctures, tablet/capsule extracts in various solvents and herb extracts. The method was applied to evaluate the phytopharmaceutical quality of St John's wort preparations available in the UK in order to test the method and investigate if they contain at least the main constituents and at what concentrations.

Photogenotoxicity of hypericin in HaCaT keratinocytes: implications for St. John's Wort supplements and high dose UVA-1 therapy.

PubMed

Traynor, N J; Beattie, P E; Ibbotson, S H; Moseley, H; Ferguson, J; Woods, J A

2005-09-15

Extract of St. John's Wort (Hypericum perforatum) is commonly used as natural remedy for treatment of mild to moderate depression. However, it contains a powerful photoactive component, hypericin, which can cause a severe photodermatitis when eaten by grazing animals (hypericism). In humans, there is evidence that supplementation with St. John's Wort can reduce the minimal erythemal dose (MED) in patients undergoing high dose UVA-1 phototherapy. This is a recent development in phototherapy where the most erythemogenic parts of the UVA spectrum are filtered out, allowing delivery of higher doses of the longer wavelengths of UVA. Although current published evidence suggests that the plasma levels of hypericin are unlikely to cause clinical phototoxicity, it has been established that photoactive compounds can cause DNA damage at sub-toxic and sub-erythemal doses, the effects of which might not be apparent for many years after the event. The present study used HaCaT keratinocytes to investigate the photoclastogenic ability of hypericin on irradiation with UVA. The results show that although the combination of hypericin and UVA light increased the genotoxic burden, when all factors are taken into account, the risk of significant photogenotoxic damage incurred by the combination of Hypericum extracts and UVA phototherapy may be low in the majority of individuals.

Early signs of recovery of Acropora palmata in St. John, US Virgin Islands

USGS Publications Warehouse

Muller, E.M.; Rogers, Caroline S.; van Woesik, R.

2014-01-01

Since the 1980s, diseases have caused significant declines in the population of the threatened Caribbean coral Acropora palmata. Yet it is largely unknown whether the population densities have recovered from these declines and whether there have been any recent shifts in size-frequency distributions toward large colonies. It is also unknown whether colony size influences the risk of disease infection, the most common stressor affecting this species. To address these unknowns, we examined A. palmata colonies at ten sites around St. John, US Virgin Islands, in 2004 and 2010. The prevalence of white-pox disease was highly variable among sites, ranging from 0 to 53 %, and this disease preferentially targeted large colonies. We found that colony density did not significantly change over the 6-year period, although six out of ten sites showed higher densities through time. The size-frequency distributions of coral colonies at all sites were positively skewed in both 2004 and 2010, however, most sites showed a temporal shift toward more large-sized colonies. This increase in large-sized colonies occurred despite the presence of white-pox disease, a severe bleaching event, and several storms. This study provides evidence of slow recovery of the A. palmata population around St. John despite the persistence of several stressors.

Enhanced recoverable energy storage density and high efficiency of SrTiO3-based lead-free ceramics

NASA Astrophysics Data System (ADS)

Yang, Haibo; Yan, Fei; Lin, Ying; Wang, Tong

2017-12-01

In this study, (1-x)SrTiO3-x(Bi0.48La0.02Na0.48Li0.02Ti0.98Zr0.02O3) [(1-x)ST-xBLNLTZ] lead-free ceramics with x = 0-0.4 were designed and fabricated using the tape casting process and the subsequent conventional solid-state sintering method. The (1-x)ST-xBLNLTZ ceramics are characterized by the excellent frequency stability of the dielectric constant, large maximum polarization (Pmax), low remnant polarization (Pr), and slim polarization-electric field (P-E) loops. For the composition of x = 0.4, Pmax is increased to 30.35 μC/cm2, 3.82 times higher than that of pure SrTiO3 (7.95 μC/cm2). The breakdown strength is larger than 200 kV/cm for all the samples. The sample with x = 0.1 exhibits a high recoverable energy storage density (Wrec) of 2.59 J/cm3 and a high energy storage efficiency (η) of 85% simultaneously. The results demonstrate that the (1-x)ST-xBLNLTZ ceramics are promising lead-free materials for high energy storage applications.

Performance of starter in yogurt supplemented with soy protein isolate and biotransformation of isoflavones during storage period.

PubMed

Pham, T Thuy; Shah, Nagendra P

2009-01-01

In this study, soy protein isolate (SPI) (4%, v/w) was supplemented to the yogurt mix to increase the amount of biologically active isoflavone in yogurt (SY). The control yogurt was without any SPI supplementation (USY). The supplementation significantly (P < 0.05) increased the lactose metabolism by the yogurt starter including Lactobacillus delbrueckii ssp. bulgaricus ATCC 11842 (Lb 11842) and Streptococcus thermophilus ST 1342 (ST 1342) during the fermentation process by 4.7%. The starter produced more acetic acid and less lactic acid in SY than that in USY and altered the ratio of lactic and acetic acid during the entire storage period. The viability of both Lb 11842 and ST 1342 in SY was significantly (P < 0.05) lower than that in USY from 14 d of the storage period, however, their concentration still remained high (8.11 to 8.84 log CFU/g). The starter transformed 72.8% of total inactive isoflavone glycosides (IG) to active isoflavone aglycones (IA), increasing the IA content from 1.35 to 15.01 mg/100 g sample. During the storage period, IA concentration slowly rose from 15.02 to 15.51 mg/100 g sample.

Protective effects of St. John's wort extract and its component hyperforin against cytokine-induced cytotoxicity in a pancreatic beta-cell line.

PubMed

Menegazzi, Marta; Novelli, Michela; Beffy, Pascale; D'Aleo, Valentina; Tedeschi, Elisa; Lupi, Roberto; Zoratti, Elisa; Marchetti, Piero; Suzuki, Hisanori; Masiello, Pellegrino

2008-01-01

In both type 1 and type 2 diabetes, increased production of cytokines on autoimmune or metabolic basis is supposed to trigger an inflammatory process leading to dysfunction and death of pancreatic beta-cells. Therefore, anti-inflammatory pharmacological approaches aimed at blocking cytokine signalling pathways and consequent cytotoxicity in beta-cells are highly advisable. Based on previous evidence of cytokine antagonistic effects in other cell types, we explored the protective action of Hypericum perforatum (St-John's-wort) extract and its component hyperforin against cytokine-induced functional impairment and apoptosis in the INS-1E beta-cell line, searching for the underlying mechanisms. The results showed that either St-John's-wort extract or hyperforin (at 1-3 microM) prevented cytokine-induced impairment in glucose-stimulated insulin secretion and protected cells against apoptosis in a dose-dependent fashion. Inducible-NO-synthase expression was also potently hindered by the vegetal compounds. Interestingly, cytokine-induced activations of the signal-transducer-and-activator-of-transcription-1 (STAT-1) and the nuclear-factor-kappaB (NF-kappaB) were both down-regulated by SJW extract or HPF (range 0.5-5 microM) when evaluated by electrophoretic-mobility-shift-assay. Other transcription factors (CBF-1, SP-1) were unaffected. Components of SJW extract other than HPF were much less effective in down-regulating cytokine signalling. Significantly, inhibition of cytokine-elicited STAT-1 and NF-kappaB activation was confirmed in isolated rat and human islets incubated in the presence of these vegetal compounds. In conclusion, St-John's-wort extract and hyperforin are non-peptidyl compounds which, at low concentrations, target key mechanisms of cytokine-induced beta-cell injury, thereby improving beta-cell function and survival. Thus, they are potentially valuable for the prevention or limitation of beta-cell loss in diabetes.

Fate and transport modeling of selected chlorinated organic compounds at Operable Unit 3, U.S. Naval Air Station, Jacksonville, Florida

USGS Publications Warehouse

Davis, J. Hal

2000-01-01

Ground water contaminated by the chlorinated organic compounds trichloroethene (TCE), cis-dichloroethene (DCE), and vinyl chloride (VC) has been found in the surficial aquifer beneath the Naval Aviation Depot at the U.S. Naval Air Station, Jacksonville, Florida. The affected area is designated Operable Unit 3 (OU3) and covers 134 acres adjacent to the St. Johns River. Site-specific ground-water flow modeling was conducted at OU3 using MODFLOW, and solute-transport modeling was conducted using MT3DMS. Simulations using a low dispersivity value, which resulted in the highest concentration discharging to the St. Johns River, gave the following results. At 60 years traveltime, the highest concentration of TCE associated with the Area C plume had discharged to St. Johns River at a level that exceeded 1x103 micrograms per liter (ug/L). At 100 years traveltime, the highest concentration of TCE associated with the Area D plume had discharged to the river at a level exceeding 3x103 ug/L. At 200 years traveltime, the Area B plume had not begun discharging to the river. Simulations using a first-order decay rate half-life of 13.5 years (the slowest documented) at Area G caused the TCE to degrade before reaching the St. Johns River. If the ratio of the concentrations of TCE to cis-DCE and VC remained relatively constant, these breakdown products would not reach the river. However, the actual breakdown rates of cis-DCE and VC are unknown. Simulations were repeated using average dispersivity values with the following results. At 60 years traveltime, the highest concentration of TCE associated with the Area C plume had discharged to St. Johns River at a level exceeding 4x102 ug/L. At 100 years traveltime, the highest concentration of TCE associated with the Area D plume had discharged to the river at a level exceeding 1x103 ug/L. At 200 years traveltime, the Area B plume had not begun discharging to the river. 'Pump and treat' was simulated as a remedial alternative. The concentration of TCE at Area B trended rapidly downward; however, one isolated pocket of TCE remained because of the low-permeability sediments present at this area. The concentration of TCE at Area C trended rapidly downward and was below 1 ug/L in about 16 years. The concentration of TCE at Area D also trended rapidly downward and was below 1 mg/L in about 18 years.

Implementing the INTERGROWTH-21st fetal growth standards in France: a 'flash study' of the College Français d'Echographie Foetale (CFEF).

PubMed

Stirnemann, J J; Fries, N; Bessis, R; Fontanges, M; Mangione, R; Salomon, L J

2017-04-01

To assess potential differences in fetal size between the French population and the international population from the INTERGROWTH-21 st (IG-21 st ) Project and to measure the impact of switching to the IG-21 st reference standards for fetal size. This was a nationwide cross-sectional study of fetal ultrasound biometry. Low-risk singleton pregnancies were recruited prospectively within the network of the national French College of Fetal Ultrasound, CFEF, over a 6-week period. Further selection was performed based on the criteria of the IG-21 st Project in order to obtain a comparable population. Head circumference (HC) was used as the main fat-free skeletal measure of growth for comparison of French fetal size with that of the IG-21 st population. The impact of switching to the IG-21 st fetal growth standards was quantified by comparing Z-scores calculated using the IG-21 st standards with those calculated using locally derived reference ranges for HC, abdominal circumference (AC) and femur length (FL). Following selection, 4858 cases were analyzed. The distribution of HC demonstrated clear similarity between our French population and the IG-21 st population: our observed centile curves closely matched those of IG-21 st and the Z-scores were close to 0 across gestational age. The IG-21 st standards performed as well as did locally derived charts in terms of screening for small-for-gestational age by AC, while they identified significantly fewer small FL values than were expected and than did the locally derived charts. Under strict selection criteria, fetal size in France is similar to that of the international population used in the IG-21 st Project. The discrepancies in FL are unlikely to impact on prenatal management. Therefore, switching from locally derived reference ranges to the IG-21 st standards appears to be a safe option. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd.

Minutes of the Fiber Optics Standardization Planning Meeting Held at Dayton, Ohio on 1-3 August 1983.

DTIC Science & Technology

1983-12-12

a C. LU I- Ch . Ul wb EIA has rededicated itself to standards for the Fiber Optics technologies - this rededication has taken various forms since the... 7845 Center 6000 E. 21st St. (AV)724- 7845 Indianapolis, IN 46218 John Slivinski USAF ASD/ENASF 513-255-3586 WPAFB, OH 45433 Sabrina Strahler DESC-ESS

Preparing Environments for the 21st Century: Proceedings of the Cuyahoga Community College Faculty Symposium (Cleveland, Ohio, March 5, 1994).

ERIC Educational Resources Information Center

Cuyahoga Community Coll., Cleveland, OH.

Focusing on current environmental issues and strategies for preparing for the future, this document provides the following conference papers: (1) "Preparing Environments for the 21st Century," by Bailus Walker, Jr.; (2) "Green vs. Greed: Development and Conservation," by John Ferrara; (3) "Plants and People: A Developing Relationship," by Alan…

Hurricanes and anchors: preliminary results from the National Park Service regional reef assessment program

USGS Publications Warehouse

Rogers, Caroline S.

1994-01-01

The U .S . National Park Service NPS began a Regional Assessment Program for coral reefs in the U.S. Virgin Islands and Florida in 1988. Scientists from NPS and six other institutions have now established longterm monitoring sites at Virgin Islands National Park St. John, USVI, Buck Island Reef National Monument St. Croix, USVI, Biscayne National Park Florida and Fort Jefferson National Monument Florida. Hurricane Hugo passed through the USVI in 1989, causing severe destruction in some reef areas while leaving others untouched. Patchy damage to reefs in Florida was also noted after Hurricane Andrew; damage from this August 1992 storm is still being assessed. Fort Jefferson National Monument escaped the onslaught of Andrew. No significant recovery in live coral cover has been evident at the Buck Island or Virgin Islands National Park VINP study sites 3.5 years after Hurricane Hugo. Similarly, no recovery was evident at another site in St. John which was destroyed by a large anchor 4.5 years ago.

Non-timber forest products in Central Appalachia: market opportunities for rural development (poster abstract)

Treesearch

A.L. Hammett; J.L. Chamberlain

1999-01-01

The gathering of forest products has supplemented the incomes of Central Appalachia residents for many generations. Non-timber forest products (NTFPs) can be grouped within four general categories: edibles such as mushrooms; medicinal and dietary supplements, including ginseng, gingko, and St. John?s wort; floral products such as moss, grape vines, and ferns; and...

Ideas of the Founders on Constitutional Government: Resources for Teachers of History and Government.

ERIC Educational Resources Information Center

Patrick, John J., Ed.

The political ideas of John Adams, Alexander Hamilton, John Jay, Thomas Jefferson, James Madison, and other Founders of the United States have been a rich civic legacy for successive generations of citizens. An important means of ensuring that these ideas on constitutional government continue to inspire and guide people in the 21st century lies in…

Data Management, the Victorian era child of the 21st century

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farber, Rob

2007-03-30

Do you remember when a gigabyte disk drive was “a lot” of storage in that by-gone age of the 20th century? Still in our first decade of the 21st century, major supercomputer sites now speak of storage in terms of petabytes, 1015 bytes, or six orders of magnitude increase in capacity over a gigabyte! Unlike our archaic “big” disk drive where all the data was in one place, HPC storage is now distributed across many machines and even across the Internet. Collaborative research engages many scientists who need to find and use each others data, preferably in an automated fashion,more » which complicates an already muddled problem.« less

Fate and Transport Modeling of Selected Chlorinated Organic Compounds at Hangar 1000, U.S. Naval Air Station, Jacksonville, Florida

USGS Publications Warehouse

Davis, J. Hal

2003-01-01

The Jacksonville Naval Air Station occupies 3,800 acres adjacent to the St. Johns River in Jacksonville, Florida. Two underground storage tanks at Hangar 1000 contained solvents from the late 1960s until they were removed in 1994. Ground-water samples at one of the tank sites had levels of trichloroethene (TCE) and total dichloroethene (DCE) of 8,710 micrograms per liter (mg/L) and 4,280 mg/L, respectively. Vinyl chloride (VC) at the site is the result of the biodegradation of DCE. Ground water beneath Hangar 1000 flows toward a storm sewer. TCE and DCE plumes travel with the ground water and presumably have reached the storm sewer, which discharges to the St. Johns River. Simulation of solute transport indicates that the traveltime from the storage tank site to the storm sewer is 16, 14, and 12 years for TCE, DCE, and VC respectively. TCE has the longest traveltime because it has the highest retardation factor at 2.5, DCE takes less time with a retardation factor of 2.0, and VC has the quickest traveltime because it has the lowest retardation factor of 1.7. Based on modeling results, the release of contaminants in the aquifer occurred more than 16 years ago. Model-derived dispersivity values at Hangar 1000 were: longitudinal 1.5 feet (ft), transverse 0.27 ft, and vertical 0.27 ft. The model-derived first order decay rates for biodegradation of TCE, DCE, and VC were 0.0002 per day (d-1), 0.0002 d-1, and 0.06 d-1, respectively. These rates are equivalent to half-lives of 13.7 years for TCE and DCE and 17 days for VC. Source area reductions in contaminant concentrations of 50 and 100 percent were modeled to simulate remediation. As expected, reducing the source concentration by 50 percent resulted in eventual TCE, DCE, and VC concentrations that were half of the original concentrations. About 16 years were needed for new steady-state TCE concentrations to develop, about 14 years for DCE, and about 12 years for VC. Reducing the source area concentrations by 100 percent in the model eventually resulted in zero concentrations of TCE, DCE, and VC. The modeled period of time for the contaminants to be removed from the aquifer once the source was removed was about 17 years for TCE, 15 years for DCE, and 13 years for VC.

The 91st Infantry in World War I -- Analysis of an AEF Division’s Efforts to Achieve Battlefield Success

DTIC Science & Technology

2013-06-13

collaboration with John J. Pershing, “Who Won the War” ( Typescript copy held in the Duane N. Diedrich Collection, Clements Library, University of...trusted to luck.”74 73The Training and Employment of Divisions, 1918, 71. 74Diary of Lieutenant Charles H. Paul, 364th Infantry, 91st Division ( typescript ...accessed 19 May 2013). Diary of Gaylen Snow, 362nd Infantry, 91st Division. Typescript held at Brigham Young University, UT. 79 Diary of Lieutenant

62. Neg. No. F75A, Jun 18, 1930, INTERIORWAREHOUSE, 1ST FLOOR, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

62. Neg. No. F-75A, Jun 18, 1930, INTERIOR-WAREHOUSE, 1ST FLOOR, STORAGE OF AUTOMOBILE COMPONENTS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

Proceedings of U.S. Navy Symposium on Arctic/Cold Weather Operations of Surface Ships (1985) Held on 3-4 December 1985

DTIC Science & Technology

1985-01-01

447 John D. Crowley, Bath Iron Works Corp. 01W Spray Ice Bonding to Superstructure Coatings ..... ............... ... 453 Prof. W.M...20362 John Crowley (202) 692-1304 Bath Iron Works 700 Wastington Street John F. Carter Bath , ME 04530 TIAC (202) 443-3311, Ext. 3709 4999 St. Catherine...22031 vi, (703) 698-6225 David Moore Naval Sea Systems Command Winn Price Code SEA 55X24 Bath Iron Works Washington, DC 20362 700 Washington Street (202

2. Wayne Chandler, Photographer, November 2000 Photographic copy of photograph ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Wayne Chandler, Photographer, November 2000 Photographic copy of photograph (original print in possession of Heritage Research, Ltd. Menomonee Falls, WI) John N. Vogel, Photographer, July 2000 View to southeast. Aerial view of Soo Complex. From left to right, locks are Sabin, Davis, New Poe, and MacArthur - St. Mary's Falls Canal, Soo Locks, St. Mary's River at Falls, Sault Ste. Marie, Chippewa County, MI

Nonhuman Primates are Protected from Smallpox Virus or Monkeypox Virus Challenges by the Antiviral Drug ST-246

DTIC Science & Technology

2009-06-01

Drug ST-246 John Huggins,1 Arthur Goff,1 Lisa Hensley,1 Eric Mucker,1 Josh Shamblin,1 Carly Wlazlowski,1 Wendy Johnson,1 Jennifer Chapman,1 Tom Larsen...Hauer, M. Layton , J. McDade, M. T. Osterholm, T. O’Toole, G. Parker, T. Perl, P. K. Russell, K. Tonat, and the Working Group on Civilian Biodefense

May through July 2015 storm event effects on suspended-sediment loads, sediment trapping efficiency, and storage capacity of John Redmond Reservoir

USGS Publications Warehouse

Foster, Guy M.; King, Lindsey R.

2016-06-20

The Neosho River and its primary tributary, the Cottonwood River, are the main sources of inflow to John Redmond Reservoir in east-central Kansas. Storm events during May through July 2015 caused large inflows of water and sediment into the reservoir. The U.S. Geological Survey, in cooperation with the Kansas Water Office, and funded in part through the Kansas State Water Plan Fund, computed the suspended-sediment inflows to, and trapping efficiency of, John Redmond Reservoir during May through July 2015. This fact sheet summarizes the quantification of suspended-sediment loads to and from the reservoir during May through July 2015 storm events and describes reservoir sediment trapping efficiency and effects on water-storage capacity.

Potentiometric surface of the upper Floridan Aquifer in the St. Johns River Water Management District and vicinity, Florida, May 1994

USGS Publications Warehouse

Schiffer, D.M.; O'Reilly, A. M.; Phelps, G.G.; Bradner, L.A.; Halford, K.J.; Spechler, R.M.

1994-01-01

This map depicts the potentiometric surface of the Upper Floridan aquifer in the St. Johns River Water Management District and vicinity for May 1994. The map is based on water-level measurements made at approximately 1,000 wells and several springs. Data on the map were contoured using 5-foot contour intervals in most areas. The potentiometric surface of this karstic aquifer generally reflects land surface topography. Potentiometric surface highs often correspond to topographic highs, which are areas of surficial recharge to the Upper Floridan aquifer. Springs within topographic lows along with areas of more diffuse upward leakage are natural zones of discharge. Municipal, agricultural, and industrial withdrawals have lowered the potentiometric surface in some areas. The potentiometric surface ranged from 125 feet above sea level in Polk County to 32 feet below sea level in Nassau County. Water levels in May 1994 generally were 0 to 3 feet lower than those measured in May 1993. Water levels in May 1994 in northeast Florida generally were 0 to 3 feet higher than in September 1993, except in the lower St. Johns River basin, where water levels were 0 to 4 feet lower than in September 1993. In the rest of the mapped area, water levels in May 1994 generally were 0 to 4 feet lower than those measured in September 1993.

The risk-benefit profile of commonly used herbal therapies: Ginkgo, St. John's Wort, Ginseng, Echinacea, Saw Palmetto, and Kava.

PubMed

Ernst, Edzard

2002-01-01

Because use of herbal remedies is increasing, a risk-benefit profile of commonly used herbs is needed. This article provides a clinically oriented overview of the efficacy and safety of ginkgo, St. John's wort, ginseng, echinacea, saw palmetto, and kava. Wherever possible, assessments are based on systematic reviews of randomized clinical trials. Encouraging data support the efficacy of some of these popular herbal medicinal products, and the potential for doing good seems greater than that for doing harm. The published evidence suggests that ginkgo is of questionable use for memory loss and tinnitus but has some effect on dementia and intermittent claudication. St. John's wort is efficacious for mild to moderate depression, but serious concerns exist about its interactions with several conventional drugs. Well-conducted clinical trials do not support the efficacy of ginseng to treat any condition. Echinacea may be helpful in the treatment or prevention of upper respiratory tract infections, but trial data are not fully convincing. Saw palmetto has been shown in short-term trials to be efficacious in reducing the symptoms of benign prostatic hyperplasia. Kava is an efficacious short-term treatment for anxiety. None of these herbal medicines is free of adverse effects. Because the evidence is incomplete, risk-benefit assessments are not completely reliable, and much knowledge is still lacking.

Obituary: John Louis Perdrix, 1926-2005

NASA Astrophysics Data System (ADS)

Orchiston, D. Wayne

2006-12-01

John Perdrix, astronomical historian and co-founder of the Journal of Astronomical History and Heritage, died on 27 June 2005. John Louis Perdrix was born in Adelaide, Australia, on 30 June 1926. After studying chemistry at Melbourne Technical College and working in industry, he joined the Commonwealth Scientific and Industrial Research Organisation's Division of Minerals and Geochemistry. In 1974 the Division relocated to the Western Australian capital, Perth, and John spent the rest of his working life there involved in geochemical research. From his teenage years John had a passion for astronomy, which he fine-tuned through the Astronomical Society of Victoria and the Victorian Branch of the British Astronomical Association. He was very active in both groups, serving as President of the former and Secretary/Treasurer of the latter. He was also an FRAS, and a member of the AAS, the BAA parent body, and the IAU (Commission 41)?no mean feat for an Australian amateur astronomer. Throughout his life, he was a strong advocate of close amateur-professional relations. John's main research interest was history of astronomy, and over the years he wrote a succession of research papers, mainly about aspects of Australian astronomy. His well-researched and neatly-illustrated papers on the Melbourne Observatory and the Great Melbourne Telescope are classics, and when the Observatory's future was in the balance they played a key role in the State Government's decision to convert this unique facility into a museum precinct. To support his research activities, John built up an amazing library that developed its own distinctive personality and quickly took over his house and garage before invading commercial storage facilities! Apart from writing papers, John had an even greater passion for editing and publishing. From 1985 to 1997 he produced the Australian Journal of Astronomy, and in 1998 this was replaced by the Journal of Astronomical History and Heritage (JAH2). Both journals appeared under the banner of his own publishing house, Astral Press, until 2005 when JAH2 was transferred to the Centre of Astronomy at James Cook University. When cancer was first diagnosed, this did not deter John, and he continued to pursue his astronomical and editorial interests. Early in 2005 the cancer was in remission and John decided to make one final overseas trip, a long-anticipated visit to St. Petersburg. It was while he was returning to Australia that the illness aggressively reappeared, and he was taken off the airplane at Dubai and died peacefully in Rashid Hospital three days later. He was just three days short of his seventy-ninth birthday. Always the consummate gentleman, John Perdrix had a keen sense of humor and was wonderful company. He will be greatly missed by all who knew him. Our condolences go to his six children, Louise, John, Timothy, Fleur, Lisa and Angella.

Hydrologic and geochemical approaches for determining ground-water flow components

USGS Publications Warehouse

Hjalmarson, H.W.; Robertson, F.N.

1991-01-01

Lyman Lake is an irrigation-storage reservoir on the Little Colorado River near St. Johns, Arizona. The main sources of water for the lake are streamflow in the Little Colorado River and ground-water inflow from the underlying Coconino aquifer. Two approaches, a hydrologic analysis and a geochemical analysis, were used to compute the quantity of ground-water flow to and from Lyman Lake. Hydrologic data used to calculate a water budget were precipitation on the lake, evaporation from the lake, transpiration from dense vegetation, seepage through the dam, streamflow in and out of the lake, and changes in lake storage. Geochemical data used to calculate the ground-water flow components were major ions, trace elements, and the stable isotopes of hydrogen and oxygen. During the study, the potentiometric level of the Coconino aquifer was above the lake level at the upstream end of the lake and below the lake level at the downstream end. Hydrologic and geochemical data indicate that about 10 percent and 8 percent, respectively, of the water in the lake is ground-water inflow and that about 35 percent of the water in the Little Colorado River 6 miles downgradient from the lake near Salado Springs is ground water. These independent estimates of ground-water flow derived from each approach are in agreement and support a conceptual model of the water budget.

Peter St. John | NREL

Science.gov Websites

for microbial strain design to optimize the production of value-added chemicals from lignin using Pseudomonas putida. Featured Publications "A quantitative model for the prediction of sooting tendency

Mania and Psychosis Associated with St. John's Wort and Ginseng

PubMed Central

Faubion, Matthew D.

2005-01-01

The use of complimentary/alternative medicine has become popular as evidenced by grocery store aisles and “infomercials” devoted to herbal products. These products are often misconstrued as safe because of their natural origin. With an increase in the consumption of these products, physicians need to be aware of their potential adverse effects. There are several popular over-the-counter herbal products that can affect one's behavior, especially resulting in acute mania and/or psychosis. This article provides an overview of existing literature regarding the increased use of herbal agents, reviews several case reports describing a potential association between herbal products (St. John's Wort and ginseng) and the development of mania and psychosis, and discusses the limitations in determining the frequency of serious adverse effects due to herbal products. PMID:21120109

KENNEDY SPACE CENTER, FLA. - Boeing workers perform a 3D digital scan of the actuator on the table. At left is Dan Clark. At right are Alden Pitard (seated at computer) and John Macke, from Boeing, St. Louis. . There are two actuators per engine on the Shuttle, one for pitch motion and one for yaw motion. The Space Shuttle Main Engine hydraulic servoactuators are used to gimbal the main engine.

NASA Image and Video Library

2003-09-03

KENNEDY SPACE CENTER, FLA. - Boeing workers perform a 3D digital scan of the actuator on the table. At left is Dan Clark. At right are Alden Pitard (seated at computer) and John Macke, from Boeing, St. Louis. . There are two actuators per engine on the Shuttle, one for pitch motion and one for yaw motion. The Space Shuttle Main Engine hydraulic servoactuators are used to gimbal the main engine.

Four bills of health issued from Malta by the Order of St John.

PubMed Central

Cassar, P.

1979-01-01

The specimens here described enlarge our knowledge of the bills of health of the Order of St John issued from Malta, an aspect of public health that had hitherto remained unexplored. These lone survivors from a vanished by-way of Maltese medical history formed, in their age, an integral part of the daily social, commercial and sanitary pattern of life in Malta. The earliest met so far, and described in the present series, dates from 1713; two belong to 1766 and another dates from 1794. A further bill, issued in 1782, has been published elsewhere. The chance preservation of these documents in unlikely places, as here indicated, makes it probable that additional ones may eventually come to light. Images Plate 2 Plate 1 PMID:376696

Cardiorespiratory fitness not sedentary time or physical activity is associated with cardiometabolic risk in active older adults.

PubMed

Pollock, R D; Duggal, N A; Lazarus, N R; Lord, J M; Harridge, S D R

2018-02-10

Sedentary time (ST) and moderate-to-vigorous physical activity (MVPA) are associated with cardiometabolic health. Cardiorespiratory fitness (CRF) is also implicated but often overlooked in health recommendations. This study assessed the relationships between ST, MVPA, CRF, and cardiometabolic health in highly active older individuals. 125 healthy amateur cyclists aged 55 to 79 years had their ST and MVPA levels assessed by actigraphy over a 7-day period. CRF was assessed using a maximal effort cycle ergometry test to determine VO 2max with results normalized to both body mass and fat-free mass measured by DXA. Markers of cardiometabolic risk (blood glucose, triglycerides, cholesterol, HDL, LDL, Insulin, HOMA IR, blood pressure, and body fat) were assessed and used to determine cumulative cardiometabolic risk. Multiple linear regression was used to assess ST, MVPA, and CRF associations with cardiometabolic health with the relationship between activity levels and CRF determined. CRF was associated with training volume (P = .003), but not ST or MVPA. A high CRF was associated with lower cumulative cardiometabolic risk, body fat percentage, triglyceride, and HDL levels (P < .05 in all cases). MVPA was negatively associated with body fat percentage, while ST was not associated with any marker of cardiometabolic risk when adjusting for activity levels. An association between CRF and cardiometabolic risk even in a group of older individuals with high fitness levels highlights the importance that CRF may have in maintaining health. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Preliminary economic analysis of aquifer winter-chill storage at the John F. Kennedy airport

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fox, E.C.; Thomas, J.F.

A conceptual design was formulated in conjuction with a cost analysis to determine the feasibility of retrofitting the present John F. Kennedy (JFK) airport air-conditioning system with an aquifer cold water storage system. It appears technically feasible to chill and store aquifer water at the airport site during the winter months for later air-conditioning use. However, the economic analysis shows that although a significant energy savings is realized, the money saved from reduced energy costs would not be enough to recover the necessary capital investment over a 20-year period. JFK airport may be a poor economic choice for an aquifermore » cold water storage demonstration site due to site specific problems, and other sites may provide economic incentive.« less

20. Photo copy of photograph, (original owned by John King, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

20. Photo copy of photograph, (original owned by John King, Berea, KY), photographer unknown, ca. 1935. VIEW SOUTH, CCC CAMP PARSONS IN BACKGROUND, BLACKSMITH SHOP ON LEFT, TRUCK STORAGE GARAGE IN FOREGROUND. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

The history of sturgeon in the Baltic Sea

USGS Publications Warehouse

Popovic, Danijela; Panagiotopoulou, Hanna; Baca, Mateusz; Stefaniak, Krzysztof; Mackiewicz, Pawel; Makowiecki, Daniel; King, Tim L.; Gruchota, Jakub; Weglenski, Piotr; Stankovic, Anna

2014-01-01

For the past 2000 years at least, A. o. oxyrinchus has been the dominant sturgeon in the Baltic Sea, indicating a much earlier origin than previously suggested. The most similar extant sturgeon populations to the extinct Baltic stock are those from the St John and St Lawrence rivers in Canada. These populations should be considered the best source of breeding material for the ongoing sturgeon restitution programmes in Poland and Germany.

Recruitment and Selection of Minorities in High-Tech Organizations. A Sociological Perspective.

DTIC Science & Technology

1984-09-01

Gretchen M. Luebbe Doris R. Entwisle Nancy A. Madden Joyce L. Epstein Kirk Nabors James Fennessey Alejandro Portes Denise C. Gottfredson Donald C. Rickert...Jr. Gary D. Gottfredson Laura Hersh Salganik Linda S. Gottfredson Robert E. Slavin Edward J. Harsch Jane St. John John H. Hollifield Valarie...and intelligence --as the primary determinants of minority and female underrepresentation in high-tech occupations. Despite voluminous research

Proceedings of the Second Life Education Workshop, Part of the Second Life Community Convention (1st, San Francisco, California, August 18-20, 2006)

ERIC Educational Resources Information Center

Livingstone, Daniel, Ed.; Kemp, Jeremy, Ed.

2006-01-01

This document is a compilation of 14 papers from presentations and posters of the Second Life Education Workshop at the Second Life Community Convention, presented at the Fort Mason Centre in San Francisco, California in August 2006. Following a foreword (John Bransford and Drue Gawel); preface (John Lester); and word from the chairs (Daniel…

Changes of microbial spoilage, lipid-protein oxidation and physicochemical properties during post mortem refrigerated storage of goat meat.

PubMed

Sabow, Azad Behnan; Sazili, Awis Qurni; Aghwan, Zeiad Amjad; Zulkifli, Idrus; Goh, Yong Meng; Ab Kadir, Mohd Zainal Abidin; Nakyinsige, Khadijah; Kaka, Ubedullah; Adeyemi, Kazeem Dauda

2016-06-01

Examined was the effect of post mortem refrigerated storage on microbial spoilage, lipid-protein oxidation and physicochemical traits of goat meat. Seven Boer bucks were slaughtered, eviscerated and aged for 24 h. The Longissimus lumborum (LL) and Semitendinosus (ST) muscles were excised and subjected to 13 days post mortem refrigerated storage. The pH, lipid and protein oxidation, tenderness, color and drip loss were determined in LL while microbiological analysis was performed on ST. Bacterial counts generally increased with increasing aging time and the limit for fresh meat was reached at day 14 post mortem. Significant differences were observed in malondialdehyde (MDA) content at day 7 of storage. The thiol concentration significantly reduced as aging time increased. The band intensities of myosin heavy chain (MHC) and troponin-T significantly decreased as storage progressed, while actin remained relatively stable. After 14 days of aging, tenderness showed significant improvement while muscle pH and drip loss reduced with increase in storage time. Samples aged for 14 days had higher lightness (P < 0.05) and lower (P < 0.05) yellowness and redness. Post mortem refrigerated storage influenced oxidative and microbial stability and physico-chemical properties of goat meat. © 2016 Japanese Society of Animal Science.

How did climate drying reduce ecosystem carbon storage in the forest-steppe ecotone? A case study in Inner Mongolia, China.

PubMed

Zhang, Yuke; Liu, Hongyan

2010-07-01

The projected recession of forests in the forest-steppe ecotone under projected climate drying would restrict the carbon sink function of terrestrial ecosystems. Previous studies have shown that the forest-steppe ecotone in the southeastern Inner Mongolia Plateau originally resulted from climate drying and vegetation shifts during the mid- to late-Holocene, but the interrelated processes of changing soil carbon storage and vegetation and soil shifts remain unclear. A total of 44 forest soil profiles and 40 steppe soil profiles were excavated to determine soil carbon storage in deciduous broadleaf forests (DBF), coniferous forests (CF) and steppe (ST) in this area. Carbon density was estimated to be 106.51 t/hm(2) (DBF), 73.20 t/hm(2) (CF), and 28.14 t/hm(2) (ST) for these ecosystems. Soil organic carbon (SOC) content was negatively correlated with sand content (R = -0.879, P < 0.01, n = 42), and positively correlated with silt (R = 0.881, P < 0.01, n = 42) and clay (R = 0.858, P < 0.01, n = 42) content. Consistent trends between fractions of coarse sand and a proxy index of relative aridity in sediment sequences from two palaeo-lakes further imply that climate drying reduced SOC through coarsening of the soil texture in the forest-steppe ecotone. Changes in carbon storage caused by climate drying can be divided into two stages: (1) carbon storage of the ecosystem was reduced to 68.7%, mostly by soil coarsening when DBF were replaced by CF at approximately 5,900 (14)C years before present (BP); and (2) carbon storage was reduced to 26.4%, mostly by vegetation shifts when CF were replaced by ST at approximately 2,900 (14)C years BP.

Atypical Antidepressants

MedlinePlus

... dangerous reactions when combined with certain medications or herbal supplements. Serotonin syndrome. Rarely, an antidepressant can cause high ... antidepressants, certain pain or headache medications, and the herbal supplement St. John's wort. Symptoms of serotonin syndrome include ...

Cholera in Haiti and Other Caribbean Regions, 19th Century

PubMed Central

Szabo, Victoria

2011-01-01

Medical journals and other sources do not show evidence that cholera occurred in Haiti before 2010, despite the devastating effect of this disease in the Caribbean region in the 19th century. Cholera occurred in Cuba in 1833–1834; in Jamaica, Cuba, Puerto Rico, St. Thomas, St. Lucia, St. Kitts, Nevis, Trinidad, the Bahamas, St. Vincent, Granada, Anguilla, St. John, Tortola, the Turks and Caicos, the Grenadines (Carriacou and Petite Martinique), and possibly Antigua in 1850–1856; and in Guadeloupe, Cuba, St. Thomas, the Dominican Republic, Dominica, Martinique, and Marie Galante in 1865–1872. Conditions associated with slavery and colonial military control were absent in independent Haiti. Clustered populations, regular influx of new persons, and close quarters of barracks living contributed to spread of cholera in other Caribbean locations. We provide historical accounts of the presence and spread of cholera epidemics in Caribbean islands. PMID:22099117

Expedition54_Education_In-Flight_College_St_Benedict_and_St_Johns_university_051_1835_620599

NASA Image and Video Library

2018-02-21

Aboard the International Space Station, Expedition 54 Flight Engineers Mark Vande Hei and Scott Tingle of NASA discussed life and research on the orbiting laboratory with students from the College of St. Benedict and Saint John’s University in Collegeville, Minnesota, during an in-flight educational event Feb. 20. Vande Hei, who received a degree from Saint John’s University in 1989, is returning to Earth Feb. 27 (U.S. time) after a five-and-a-half-month mission on the station while Tingle will remain aloft until early June.

Evaluating an Ice-Storage System in a Deregulated Environment.

ERIC Educational Resources Information Center

Staniewicz, Theodore J.; Watson, Joseph J.

2001-01-01

Examines the difficulties the electric industry's deregulation created for St. Joseph's University's (Philadelphia) development of a thermal ice-storage system as part of its HVAC design and the school's solution. A monthly equipment summary sheet with year-to-date figures is provided. (GR)

Sperm storage influences the potential for spontaneous acrosome reaction of the sperm in the newt Cynops pyrrhogaster.

PubMed

Kon, Shinnosuke; Sato, Tae; Endo, Daisuke; Takahashi, Tomoe; Takaku, Akio; Nakauchi, Yuni; Toyama, Fubito; Meyer-Rochow, Victor B; Takayama-Watanabe, Eriko; Watanabe, Akihiko

2017-12-01

Sperm storage is supposed to influence sperm quality, although the details remain unclear. In the present study, we found that sperm stored in a sperm storage site, the vas deferens of Cynops pyrrhogaster, spontaneously undergo acrosome reaction following incubation in Steinberg's salt solution (ST). Percentages of acrosome-reacted sperm increased time-dependently to about 60% in 24 hr. The concentration of cyclic adenosine monophosphate (cAMP) was elevated after incubating sperm in ST, while dibutylyl cAMP induced an acrosome reaction. Chelating of extracellular Ca 2+ suppressed the dibutylyl cAMP-induced acrosome reaction as well as spontaneous acrosome reaction in ST. These results suggest that cAMP elevation driven by Ca 2+ influx can be a cue for spontaneous acrosome reaction. Relatively low Ca 2+ concentration and pH in the vas deferens were sufficient to suppress spontaneous acrosome reaction within 1 hr. In addition, the cysteine rich secretory protein 2 gene was expressed in the vas deferens, indicating that it may be involved in the continuous suppression of spontaneous acrosome reaction. Sperm that underwent spontaneous acrosome reaction in ST was significantly increased when stored in the vas deferens for longer periods, or by males experiencing temperatures in excess of 12°C during hibernation conditions. Percentages of the spontaneously acrosome-reacted sperm were found to differ among males even though they were of identical genetic background. Taken together, C. pyrrhogaster sperm possess the potential for spontaneous acrosome reaction that does not become obvious in the vas deferens, unless promoted in correlation with sperm storage. © 2017 Wiley Periodicals, Inc.

Effects of May through July 2015 storm events on suspended sediment loads, sediment trapping efficiency, and storage capacity of John Redmond Reservoir, east-central Kansas

USGS Publications Warehouse

Foster, Guy M.

2016-06-20

The U.S. Geological Survey, in cooperation with the Kansas Water Office, computed the suspended-sediment inflows and retention in John Redmond Reservoir during May through July 2015. Computations relied upon previously published turbidity-suspended sediment relations at water-quality monitoring sites located upstream and downstream from the reservoir. During the 3-month period, approximately 872,000 tons of sediment entered the reservoir, and 57,000 tons were released through the reservoir outlet. The average monthly trapping efficiency during this period was 93 percent, and monthly averages ranged from 83 to 97 percent. During the study period, an estimated 980 acre-feet of storage was lost, over 2.4 times the design annual sedimentation rate of the reservoir. Storm inflows during the 3-month analysis period reduced reservoir storage in the conservation pool approximately 1.6 percent. This indicates that large inflows, coupled with minimal releases, can have substantial effects on reservoir storage and lifespan.

Model of Anoxic-Aerobic Wastewater Treatment at Phoenix 91st Avenue Plant

DTIC Science & Technology

1993-01-01

46 6. Storage Model; PCOD Profile 47.................... Accesion For NTS CRAMl 7. Storage Model; Oxygen Consumption Rate...69 iv 27. Compare 4 November and 17 November 1992 Data Sets; PCOD Concentrations; Storage Model .... 70 28. 4 November 1992...demand (SCOD), particulate chemical oxygen demand ( PCOD ), and the oxygen consumption rate in each stage. Mass balance equations were written for ammonia

Airborne Next: Rethinking Airborne Organization and Applying New Concepts

DTIC Science & Technology

2015-06-01

9 Kenneth Macksey, Guderian: Panzer General-revised EDITION (South Yorkshire, England: Greenhill Books, 2003), 1–20. 10 Dr. John Arquilla...Airborne Operations: Field Manual 90=26, 1–5. 14 The 1st Special Forces Regiment has five active Special Forces Groups (1st, 3rd, 5th , 7th, 10th...Oxford University Press, 1981). Headrick, in his book, describes the interplay between technology and imperialism. For the purposes of this research

Termination or Transition: A 21st Century Perspective on the Military’s Role in Conflict Resolution

DTIC Science & Technology

2009-05-01

Director, Robert F. Baumann, Ph.D. Graduate Degree Programs iii Abstract TRANSITION OR TERMINATION: A 21 ST CENTURY...1992) and James Raymer , In Search of Lasting Results: Military War Termination Doctrine (Fort Leavenworth, KS: US Army Command and General Staff... Robert E. Baumann, and John T. Fishel, Invasion, Intervention, and “Intervasion”: A Concise History of the US Army in Operation Uphold Democracy

Selective Serotonin Reuptake Inhibitors (SSRIs)

MedlinePlus

... dangerous reactions when combined with certain medications or herbal supplements. Serotonin syndrome. Rarely, an antidepressant can cause high ... antidepressants, certain pain or headache medications, and the herbal supplement St. John's wort. Signs and symptoms of serotonin ...

Tricyclic Antidepressants and Tetracyclic Antidepressants

MedlinePlus

... dangerous reactions when combined with certain medications or herbal supplements. Serotonin syndrome. Rarely, an antidepressant can cause high ... antidepressants, certain pain or headache medications, and the herbal supplement St. John's wort. Signs and symptoms of serotonin ...

76 FR 6500 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-04

... Haigney comment, Sutherland comment, Black and Gross comment, Berg comment, PIABA comment; St. John's..., Steiner comment, Chalmers comment, Gladden comment, Estell comment, Sutherland comment, Furgison comment...

Recent Observations and Structural Analysis of Surge-Type Glaciers in the Glacier Bay Area

NASA Astrophysics Data System (ADS)

Mayer, H.; Herzfeld, U. C.

2003-12-01

The Chugach-St.-Elias Mountains in North America hold the largest non-polar connected glaciated area of the world. Most of its larger glaciers are surge-type glaciers. In the summer of 2003, we collected aerial photographic and GPS data over numerous glaciers in the eastern St. Elias Mountains, including the Glacier Bay area. Observed glaciers include Davidson, Casement, McBride, Riggs, Cushing, Carroll, Rendu, Tsirku, Grand Pacific, Melbern, Ferris, Margerie, Johns Hopkins, Lamplugh, Reid, Burroughs, Morse, Muir and Willard Glaciers, of which Carroll, Rendu, Ferris, Grand Pacific, Johns Hopkins and Margerie Glaciers are surge-type glaciers. Our approach utilizes a quantitative analysis of surface patterns, following the principles of structural geology for the analysis of brittle-deformation patterns (manifested in crevasses) and ductile deformation patterns (visible in folded moraines). First results will be presented.

Observing Storm Surges from Space: A New Opportunity

NASA Astrophysics Data System (ADS)

Han, Guoqi; Ma, Zhimin; Chen, Dake; de Young, Brad; Chen, Nancy

2013-04-01

Coastal tide gauges can be used to monitor variations of a storm surge along the coast, but not in the cross-shelf direction. As a result, the cross-shelf structure of a storm surge has rarely been observed. In this study we focus on Hurricane Igor-induced storm surge off Newfoundland, Canada. Altimetric observations at about 2:30, September 22, 2010 UTC (hours after the passage of Hurricane Igor) reveal prominent cross-shelf variation of sea surface height during the storm passage, including a large nearshore slope and a mid-shelf depression. A significant coastal surge of 1 m derived from satellite altimetry is found to be consistent with tide-gauge measurements at nearby St. John's station. The post-storm sea level variations at St. John's and Argentia are argued to be associated with free equatorward-propagating continental shelf waves (with phase speeds of 11-13 m/s), generated along the northeast Newfoundland coast hours after the storm moved away from St. John's. The cross-shelf e-folding scale of the shelf wave was estimated to be ~100 km. We further show approximate agreement of altimetric and tide-gauge observations in the Gulf of Mexico during Hurricane Katrina (2005) and Isaac (2012). The study for the first time in the literature shows the robustness of satellite altimetry to observe storm surges, complementing tide-gauge observations for the analysis of storm surge characteristics and for the validation and improvement of storm surge models.

St. John's wort and its component hyperforin alleviate experimental autoimmune encephalomyelitis through expansion of regulatory T-cells.

PubMed

Nosratabadi, Reza; Rastin, Maryam; Sankian, Mojtaba; Haghmorad, Dariush; Tabasi, Nafiseh; Zamani, Shahrzad; Aghaee, Azita; Salehipour, Zohre; Mahmoudi, Mahmoud

2016-05-01

Multiple sclerosis (MS) is a central nervous system disorder mainly characterized by inflammation, demyelination and axonal injury. Anti-inflammatory agents can be used to ameliorate the disease process. Hypericum perforatum L or St. John's wort is widely used as an anti-depressant and anti-inflammatory remedy in traditional and herbal medicine. Based on St. John's wort properties, the therapeutic potentials of an H. perforatum extract (HPE) and a single component, hyperforin were evaluated for effectiveness against MOG35-55-induced experimental autoimmune encephalomyelitis (EAE), an animal model for human multiple sclerosis. Female C57BL/6 mice were immunized with specific antigen MOG35-55 and then administered different doses of hyperforin or HPE post-immunization. Clinical symptoms/other relevant parameters were assessed daily. Histological analysis of the spinal cord was performed. T-cell proliferative activity was also evaluated using a BrdU assay. The effect of hyperforin on regulatory T-cells (Treg cells) was assessed using flow cytometry. The results indicate hyperforin and HPE reduced the incidence and severity of EAE, an outcome that closely correlated with an inhibition of pathological features (leukocyte infiltration and demyelination) and antigen-specific T-cell proliferation. The study also showed that hyperforin caused increased Treg cell levels in the spleen. These results indicated that hyperforin and HPE could attenuate EAE autoimmune responses by inhibiting immune cell infiltration and expansion of Treg cell and could eventually be considered as a potential candidate for use in the treatment of MS.

Comparison of Systemic and Topical Hypericum Perforatum on Diabetic Surgical Wounds.

PubMed

Altıparmak, Mehmet; Eskitaşçıoğlu, Teoman

2018-02-01

Surgical wounds in diabetic patients still remain a problem till the present day. As a common plant found around the world, Hypericum perforatum L. (Hypericaceae) is traditionally prepared as an oily extract and used as a folk remedy for various diseases such as wounds, burns, cuts, etc. This study aims to evaluate the effect of St. John's wort (Hypericum perforatum) on problematic wounds while comparing oral and topical applications. Incisional and excisional wound models were made on the dorsal regions of 54 diabetic Spraque-Dawley rats. The rats were divided into the following six groups (n = 9): Group 1: control, Group 2: diabetic, Group 3: diabetic oral Hypericum perforatum, Group 4: diabetic topical Hypericum perforatum, Group 5: diabetic oral olive oil, and Group 6: diabetic topical olive oil. Groups 3 and 4 had significantly higher tensile strength, tissue hydroxyproline concentration, and collagen density compared with Group 2. Inflammatory cell density and collagen density on day 3 were significantly higher in Groups 3 and 6 compared with Group 2. On day 21, Groups 3 and 6 had significantly higher fibroblastic activity compared with Group 2. This study has proved that oral St. John's wort has more positive effects on problematic wounds compared with topical St. John's wort and olive oil, which is a vehicle. Hypericum perforatum results with faster inflammatory response and better healing. These results could be an addition to literature about the clinical usage of Hypericum perforatum on diabetic wounds.

Species distribution, virulence factors, and antimicrobial resistance of Acinetobacter spp. isolates from dogs and cats: a preliminary study.

PubMed

Kimura, Yui; Harada, Kazuki; Shimizu, Takae; Sato, Tomomi; Kajino, Akari; Usui, Masaru; Tamura, Yutaka; Tsuyuki, Yuzo; Miyamoto, Tadashi; Ohki, Asami; Watarai, Masahisa

2018-05-12

We investigated the prevalence of virulence factors and antimicrobial resistance among 67 Acinetobacter spp. isolates, consisting of 21 Acinetobacter baumannii and 46 non-baumannii Acinetobacter from companion animals. The PCR analysis showed that the most prevalent virulence gene was afa/draBC (29.9%), followed by papC (22.4%) and cvaC (20.9%). Antimicrobial susceptibility testing revealed that resistance to gentamicin (14.9%) and ciprofloxacin (11.9%) was relatively prevalent. Five gentamicin- and/or ciprofloxacin-resistant A. baumannii strains were assigned to ST25, ST149, ST164, ST203, and ST1198. All ciprofloxacin-resistant isolates harbored point mutations in gyrA and/or parC. This is the first preliminary monitoring of animal-origin Acinetobacter spp. in Japan. © 2018 The Societies and John Wiley & Sons Australia, Ltd.

In hip osteoarthritis, Nordic Walking is superior to strength training and home-based exercise for improving function.

PubMed

Bieler, T; Siersma, V; Magnusson, S P; Kjaer, M; Christensen, H E; Beyer, N

2017-08-01

This observer-blinded, randomized controlled trial compared the short- and long-term effects of 4 months of supervised strength training (ST) in a local fitness center, supervised Nordic Walking (NW) in a local park, and unsupervised home-based exercise (HBE, control) on functional performance in 60+-year-old persons (n = 152) with hip osteoarthritis (OA) not awaiting hip replacement. Functional performance [i.e., 30-s chair stand test (primary outcome), timed stair climbing, and 6-min walk test] and self-reported outcomes (i.e., physical function, pain, physical activity level, self-efficacy, and health-related quality of life) were measured at baseline and at 2, 4, and 12 months. Based on intention-to-treat-analyses improvements [mean (95% CI)] after intervention in number of chair stands were equal in all three groups at 4 months [ST: 0.9 (0.2-1.6), NW: 1.9 (0.8-3.0), HBE: 1.1 (0.1-2.0)] but greater in the NW group [1.4 (0.02-2.8)] than in the ST group at 12 months. Generally, improvements in functional performance were greater (P < 0.001-P < 0.03) after NW compared with HBE and ST at all follow-up time points. Furthermore, NW was superior (P < 0.01) to HBE for improving vigorous physical activity and to both ST and HBE for improving (P < 0.01) mental health. These data suggest that NW is the recommended exercise modality compared with ST and HBE. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Freezing and thawing or freezing, thawing, and aging effects on beef tenderness

USDA-ARS?s Scientific Manuscript database

The objective of this study was to determine the effect of freezing and thawing or freezing and thawing with an additional aging period after frozen storage on the tenderness of longissimus lumborum (LL) and semitendinosus (ST) steaks relative to aged, fresh steaks. Left-side LL and ST (n=35 each) ...

Hyperforin depletes synaptic vesicles content and induces compartmental redistribution of nerve ending monoamines.

PubMed

Roz, Netta; Rehavi, Moshe

2004-10-22

Hyperforin, a phloroglucinol derivative found in Hypericum perforatum (St. John's wort) extracts has antidepressant properties in depressed patients. Hyperforin has a unique pharmacological profile and it inhibits uptake of biogenic monoamines as well as amino acid transmitters. We have recently showed that the monoamines uptake inhibition exerted by hyperforin is related to its ability to dissipate the pH gradient across the synaptic vesicle membrane thereby interfering with vesicular monoamines storage. In the present study we demonstrate that hyperforin induces dose-dependent efflux of preloaded [3H]5HT and [3H]DA from rat brain slices. Moreover, we show that hyperforin attenuates depolarization- dependent release of monoamines, while increasing monoamine release by amphetamine or fenfluramine. It is also demonstrated that preincubation of brain slices with reserpine is associated with dose- dependent blunting of efflux due to hyperforin. Our data indicate that hyperforin-induced efflux of [3H]5HT and [3H]DA reflect elevated cytoplasmic concentrations of the two monoamines secondary to the depletion of the synaptic vesicle content and the compartmental redistribution of nerve ending monoamines. Copyright 2004 Elsevier Inc.

12. Interior detail of bridge operator's house showing generator and ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. Interior detail of bridge operator's house showing generator and bridge operator, Mr. Gene Amonette, facing west. - Palm Valley Bridge, County Road 210 spanning Intracoastal Waterway, Ponte Vedra Beach, St. Johns County, FL

35. OUTER DRAWBRIDGE, ENTRY TO THE PROTECTIVE CORRIDOR BETWEEN THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

35. OUTER DRAWBRIDGE, ENTRY TO THE PROTECTIVE CORRIDOR BETWEEN THE RAVELIN AND THE CASTILLO, AS SEEN FROM WITHIN THE CORRIDOR - Castillo de San Marcos, 1 Castillo Drive, Saint Augustine, St. Johns County, FL

76 FR 20757 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Granting...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-13

... Education, Christine Lazaro, Esq., Supervising Attorney, Clair S. Seu, Student Intern, and Stephen Chou, Student Intern, St. John's University School of Law Securities Arbitration Clinic, dated March 15, 2011...

Low oxygen treatment prior to cold storage decreases the incidence of bitter pit in 'Golden Reinders' apples.

PubMed

Val, Jesús; Fernández, Victoria; López, Paola; Peiró, Jose María; Blanco, Alvaro

2010-02-01

The effect of subjecting 'Golden Reinders' apples to a low O(2) pre-treatment (LOT; 1-2% O(2)) was evaluated as a strategy to decrease the rate of bitter pit (BP) incidence after standard cold storage (ST). Immediately after harvest, apples were stored for 10 days at 20 degrees C under low O(2). Thereafter, apples were cold-stored (0-4 degrees C) for 4 months and changes were monitored in terms of BP incidence, fruit quality traits and mineral element concentrations. After 4 months cold storage, LOT apples presented a 2.6-fold decrease in the rate of BP incidence (14%) versus the values obtained for standard cold-stored fruits (37% BP incidence). LOT increased flesh firmness, total soluble solids and titratable acidity as compared to the quality traits determined for cold-stored fruits. Lower cortex Ca and Mg concentrations as compared to ST apples were determined in association with LOT, 2 months after cold storage. Application of a LOT prior to cold storage may be a promising strategy to reduce the incidence of BP and preserve fruit quality, which should be further investigated.

Dinosaur or Phoenix: Nuclear Bombers in the 21st Century

DTIC Science & Technology

2010-04-12

REPORT DATE 02-04-10 2. REPORT TYPE Master’s Thesis 3. DATES COVERED 31-07-09 to 16-06-10 4. TITLE AND SUBTITLE Dinosaur or Phoenix: Nuclear...WARFIGHTING SCHOOL DINOSAUR OR PHOENIX: NUCLEAR BOMBERS IN THE 21ST CENTURY by John W. Morehead Colonel, United States Air Force A paper...can argue Secretary Gates’ decision to halt development of a follow-on bomber indicates the DOD views nuclear bombers as dinosaurs no longer needed as

Dangerous Thresholds. Managing Escalation in the 21st Century

DTIC Science & Technology

2008-01-01

Escalation in the 21st Century Forrest E . Morgan n Karl P. Mueller Evan S. Medeiros n Kevin L. Pollpeter n Roger Cliff Dangerous Thresholds The RAND...impacts of U.S. policy in the current security envi- ronment: War and Escalation in South Asia, by John E . Peters, James Dickens, Derek Eaton, C...Striking First: Preemptive and Preventive Attack in U.S. National Security Policy, by Karl P. Muel- ler, Jasen J. Castillo, Forrest E . Morgan, Negeen

Experimental Validation Techniques for the Heleeos Off-Axis Laser Propagation Model

DTIC Science & Technology

2010-03-01

EXPERIMENTAL VALIDATION TECHNIQUES FOR THE HELEEOS OFF-AXIS LASER PROPAGATION MODEL THESIS John Haiducek, 1st Lt, USAF AFIT/GAP/ENP/10-M07 DEPARTMENT...Department of Defense, or the United States Government. AFIT/GAP/ENP/10-M07 EXPERIMENTAL VALIDATION TECHNIQUES FOR THE HELEEOS OFF-AXIS LASER ...BS, Physics 1st Lt, USAF March 2010 APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED. AFIT/GAP/ENP/10-M07 Abstract The High Energy Laser End-to-End

The IDF: Tactical Success - Strategic Failure, SOD, the Second Intifada and Beyond

DTIC Science & Technology

2011-05-19

the time periods in between. Additionally, Robert St. John’s biography Ben Gurion presented an interesting and useful account of one of Israel’s...Schiff, A History of the Israeli Army, 2. 9 Ibid., 4. 10 Robert St. John, Ben Gurion: The Biography of an Extraordinary Man (New York: Doubleday...Jewish settlements and Jews in Palestine’s population centers. The 1929 Arab Revolt centered on Jerusalem and consisted of Arab attacks against

An Analysis and Comparison of Two Short Writings: "Inaugural Address at the University of St. Andrew's" by J.S. Mill and "The University of Utopia" by R.M. Hutchins, Based on Five Criteria.

ERIC Educational Resources Information Center

Poirier, Jeannine M.

Focusing on the concept of education for work vs. education for living, the author presents a comparative analysis of two works on liberal education, each of which was originally delivered orally to university students: "The Inaugural Address at the University of St. Andrew" by John Stuart Mill and "The University of Utopia" by…

50 CFR Appendix E to Part 622 - Caribbean Island/Island Group Management Areas

Code of Federal Regulations, 2013 CFR

2013-10-01

..., AND SOUTH ATLANTIC Pt. 622, App. E Appendix E to Part 622—Caribbean Island/Island Group Management... 50 Wildlife and Fisheries 12 2013-10-01 2013-10-01 false Caribbean Island/Island Group Management... St. Thomas/St. John island group to Point C C 18°13′59.0606″ 65°05′33.058″ D 18°01′16.9636″ 64°57′38...

Effects of Saint John’s Wort and Vitamin E on Breast Cancer Chemotherapeutic Agents

DTIC Science & Technology

2005-05-01

studies of St. John’s wort. However, because some recent studies have identified hyperforin as a more important contributor to the pharmacological...actions of this herbal product (3), we have employed an HPLC analytical method that accurately detects and determines hyperforin . iii. As reported...the diet are not significantly different from rats maintained on the standard diet. After 2 weeks on the diet, the rats were found to have hyperforin

A Search for Warriors: The Effects of Technology on the Air Force Ethos

DTIC Science & Technology

1997-04-01

quoted by Oberstleutnant Peter F. Hauser, and Lt Col John Rawls , C., and Maj. John C. Ornduff, “Lessons from the Kriegsakademie: A Reflection of the...Engagement: A Vision for the 21st Century Air Force. Washington DC: Headquarters USAF, November 1996. Hauser, Oberstleutnant Peter F., and Rawls , Lt Col...Modern Strategy from Machiavelli to the Nuclear Age. Princeton, NJ.: Princeton University Press, 1986. “Recent Space Issues and Development.” Air Force

U.S. Virgin Islands Analysis Brief

EIA Publications

2016-01-01

The U.S. Virgin Islands (USVI), part of the Leeward Islands of the Lesser Antilles, is a U.S. territory located in the Caribbean Sea, about 600 miles southeast of Miami, Florida.1 The USVI has a total area of 134 square miles, about twice the size of Washington, DC. The islands are hilly and forested, with limited arable areas, and most food is imported.2 The largest island is St. Croix. It lies about 40 miles south of the three other inhabited islands: St. John, St. Thomas, and Water Island. Those islands are located between the Commonwealth of Puerto Rico on the west and the British Virgin Islands on the east.

High density FTA plates serve as efficient long-term sample storage for HLA genotyping.

PubMed

Lange, V; Arndt, K; Schwarzelt, C; Boehme, I; Giani, A S; Schmidt, A H; Ehninger, G; Wassmuth, R

2014-02-01

Storage of dried blood spots (DBS) on high-density FTA(®) plates could constitute an appealing alternative to frozen storage. However, it remains controversial whether DBS are suitable for high-resolution sequencing of human leukocyte antigen (HLA) alleles. Therefore, we extracted DNA from DBS that had been stored for up to 4 years, using six different methods. We identified those extraction methods that recovered sufficient high-quality DNA for reliable high-resolution HLA sequencing. Further, we confirmed that frozen whole blood samples that had been stored for several years can be transferred to filter paper without compromising HLA genotyping upon extraction. Concluding, DNA derived from high-density FTA(®) plates is suitable for high-resolution HLA sequencing, provided that appropriate extraction protocols are employed. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

PUBLICATIONS; GULF BREEZE LABORATORY

EPA Science Inventory

The bibliography, inclusive from 1967 through 1978, lists all publications authored by researchers employed by the Environmental Research Laboratory, Gulf Breeze, and its field station on St. Johns Island, SC, or by researchers conducting studies under funding or direction of the...

Permanent record. Electronic records aid in the aftermath of Joplin tornado.

PubMed

Russell, Matthew

2011-09-01

When a tornado struck St. John's Regional Medical Center in May 2011, its patient records were stored in a newly launched electronic health record system, helping prevent a bad situation from being worse.

1. GENERAL VIEW OF COMPLEX, SHOWING FACTORY BUILDING IN LEFT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. GENERAL VIEW OF COMPLEX, SHOWING FACTORY BUILDING IN LEFT FOREGROUND, GRINDING PLATFORM AT REAR OF FACTORY, AND STABLE AREA AND OVERSEER'S HOUSE TO RIGHT - Caneel Bay Plantation, General Views, Cruz Bay, St. John, VI

75 FR 23593 - Changes in Flood Elevation Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-04

..., SD 57032. Lincoln Town of Tea (09-08- November 5, 2009; The Honorable John October 28, 2009 460143 0747P). November 12, 2009; Lawler, Mayor, Town of Lennox Independent. Tea, 600 East 1st Street, Tea, SD...

75 FR 35682 - Changes in Flood Elevation Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-23

....: B- Town of Tea (09-08- November 5, 2009; The Honorable John October 28, 2009 460143 1096). 0747P). November 12, 2009; Lawler, Mayor, Town of Lennox Independent. Tea, 600 East 1st Street, Tea, SD 57064...

Forterra Concrete Products, Inc.

EPA Pesticide Factsheets

The EPA is providing notice of a proposed Administrative Penalty Assessment against Forterra Concrete Products, Inc., a business located at 511 E. John Carpenter Freeway, Irving, TX, 75062, for alleged violations at its facility located at 23600 W. 40th St

43 CFR 3206.11 - What must BLM do before issuing a lease?

Code of Federal Regulations, 2011 CFR

2011-10-01

... National Park; (4) John D. Rockefeller, Jr. Memorial Parkway; (5) Bering Land Bridge National Preserve; (6... Monument and Preserve; (9) Wrangell-St. Elias National Park and Preserve; (10) Lake Clark National Park and...

Bleaching increases likelihood of disease on Acropora palmata (Lamarck) in Hawksnest Bay, St John, US Virgin Islands

USGS Publications Warehouse

Muller, E.M.; Rogers, Caroline S.; Spitzack, Anthony S.; van Woesik, R.

2007-01-01

Anomalously high water temperatures may enhance the likelihood of coral disease outbreaks by increasing the abundance or virulence of pathogens, or by increasing host susceptibility. This study tested the compromised-host hypothesis, and documented the relationship between disease and temperature, through monthly monitoring of Acropora palmata colonies from May 2004 to December 2006, in Hawksnest Bay, St John, US Virgin Islands (USVI). Disease prevalence and the rate of change in prevalence showed a positive linear relationship with water temperature and rate of change in water temperature, respectively, but only in 2005 during prolonged periods of elevated temperature. Both bleached and unbleached colonies showed a positive relationship between disease prevalence and temperature in 2005, but the average area of disease-associated mortality increased only for bleached corals, indicating host susceptibility, rather than temperature per se, influenced disease severity on A. palmata.

Bleaching increases likelihood of disease on Acropora palmata (Lamarck) in Hawksnest Bay, St John, US Virgin Islands

USGS Publications Warehouse

Muller, E.M.; Rogers, C.S.; Spitzack, Anthony S.; van Woesik, R.

2008-01-01

Anomalously high water temperatures may enhance the likelihood of coral disease outbreaks by increasing the abundance or virulence of pathogens, or by increasing host susceptibility. This study tested the compromised-host hypothesis, and documented the relationship between disease and temperature, through monthly monitoring of Acropora palmata colonies from May 2004 to December 2006, in Hawksnest Bay, St John, US Virgin Islands (USVI). Disease prevalence and the rate of change in prevalence showed a positive linear relationship with water temperature and rate of change in water temperature, respectively, but only in 2005 during prolonged periods of elevated temperature. Both bleached and unbleached colonies showed a positive relationship between disease prevalence and temperature in 2005, but the average area of disease-associated mortality increased only for bleached corals, indicating host susceptibility, rather than temperature per se, influenced disease severity on A. palmata. ?? 2007 Springer-Verlag.

Patient goal setting as a method for program improvement/development in partial hospitalization programs.

PubMed

Gates, A

1991-12-01

Data were collected from a study of 49 patients in 1990 and 106 patients in 1991 admitted into Country View Treatment Center and Green Country Counseling Center. Country View is a 30-bed chemical dependency residential center operating under St. John Medical Center in Tulsa, Oklahoma. Green Country is an evening partial hospital chemical dependency program operating under St. John Medical Center in Tulsa, Oklahoma, The tools used in this study were the Country View Patient Self-Reporting Questionnaire, the global Rating Scale, and the Model of Recovering Alcoholics Behavior Stages and Goal Setting (Wing, 1990). These assessments were specifically designed to measure the patient's perceptions of goal setting and the patient's perspective on treatment outcome. The study outcome resulted in program improvement (Green Country evening partial hospital program) and the development of the Country View Substance Abuse Intermediate Link (SAIL) Program (day partial hospital).

Bleaching increases likelihood of disease on Acropora palmata (Lamarck) in Hawksnest Bay, St John, US Virgin Islands

NASA Astrophysics Data System (ADS)

Muller, E. M.; Rogers, C. S.; Spitzack, A. S.; van Woesik, R.

2008-03-01

Anomalously high water temperatures may enhance the likelihood of coral disease outbreaks by increasing the abundance or virulence of pathogens, or by increasing host susceptibility. This study tested the compromised-host hypothesis, and documented the relationship between disease and temperature, through monthly monitoring of Acropora palmata colonies from May 2004 to December 2006, in Hawksnest Bay, St John, US Virgin Islands (USVI). Disease prevalence and the rate of change in prevalence showed a positive linear relationship with water temperature and rate of change in water temperature, respectively, but only in 2005 during prolonged periods of elevated temperature. Both bleached and unbleached colonies showed a positive relationship between disease prevalence and temperature in 2005, but the average area of disease-associated mortality increased only for bleached corals, indicating host susceptibility, rather than temperature per se, influenced disease severity on A. palmata.

Metabolism of hyperforin, the active constituent of St. John's wort, in human liver microsomes.

PubMed

Hokkanen, Juho; Tolonen, Ari; Mattila, Sampo; Turpeinen, Miia

2011-02-14

The metabolism of hyperforin, one of the pharmacologically most active components of St. John's wort (Hypericum perforatum), was characterized in vitro using human liver microsomes and recombinant heterologously expressed P450 enzymes. A total of 57 hyperforin metabolites were detected. Of those, six were identified as monohydroxylations (M1-M6), while the others were formed via two or more hydroxylation reactions, via dehydrogenation, or by combinations of these reactions. A combined approach of cDNA-expressed recombinant CYPs, CYP-selective chemical inhibitors and correlation with CYP-specific marker activities indicated a central role of the CYP2C and CYP3A families in the metabolism of hyperforin. In addition, hyperforin was found to inhibit CYP2D6 and CYP3A4 model activities quite potently. Copyright © 2010 Elsevier B.V. All rights reserved.

Potentiometric surface of the upper Floridan Aquifer in the St. Johns Water Management District and vicinity, Florida, May 1984

USGS Publications Warehouse

Schiner, George R.; Hayes, Eugene C.

1984-01-01

This map shows the potentiometric surface of the Upper Floridan aquifer in the St. Johns River Water Management District and vicinity for May 1984. The Upper Floridan aquifer is the principal source of potable water in the area. Water-level measurements were made on approximately 1,000 wells and on several springs. The potentiometric surface is shown mostly by 5-foot contour intervals. In the Fernandina Beach area a 40-foot interval is used to show a deep cone of depression. The potentiometric surface ranged from 126 feet above sea level in Polk County to 84 feet below sea level in Nassau County. Water levels in key wells were mostly above, or less frequently, slightly below averages for May in response to diverse area rainfall patterns. Most levels in the district were about the same, or more commonly, 1 to 2 feet lower than May 1983 levels. (USGS)

Early dispersals of maize and other food plants into the Southern Caribbean and Northeastern South America

NASA Astrophysics Data System (ADS)

Pagán-Jiménez, Jaime R.; Rodríguez-Ramos, Reniel; Reid, Basil A.; van den Bel, Martijn; Hofman, Corinne L.

2015-09-01

Grindstones from Eva 2 and St. John, two of the earliest sites in northeastern South America and the southern Caribbean respectively, were subjected to starch grain analysis. Results of this study revealed that these stone artifacts were utilized to process a variety of cultivars such as maize (Zea mays), sweet potato (Ipomoea batatas), chili pepper (Capsicum spp.), achira (Canna spp.), legumes (Fabaceae), and yams (Dioscoreaceae), coupled with wild resources, most notably marunguey (Zamia spp.). Radiocarbon dates indicate that the use of plants identified at these two sites were much older than previously considered, going back to at least 7790 cal. BP at St. John and 5990 cal. BP at Eva 2. This new evidence showcases the importance of the Caribbean basin as an arena for early phytocultural dispersals. It also focuses attention on the role of navigation as a mechanism for crop diffusion in the Neotropics.

Potentiometric surface of the Floridan Aquifer, St. Johns River Water Management District and vicinity, Florida, May 1981

USGS Publications Warehouse

Schiner, George R.; Hayes, Eugene C.

1981-01-01

This map presents the potentiometric surface of the Floridan aquifer in the St. Johns River Water Management District and vicinity for May 1981. The Floridan aquifer is the principal source of potable water in the area. Water-level measurements were made in approximately 1,000 wells and at several springs. The potentiometric surface is shown mostly by 5-foot contour intervals. In the Fernandina Beach area 20 and 40-foot intervals are used to show a deep cone of depression. The potentiometric surface ranged from 122 feet above NGVD (National Geodetic Vertical Datum of 1929) in Polk County to 125 feet below NGVD in Nassau County. Water levels were at record lows in many counties due to lack of rainfall. Declines were as much as 10 feet and commonly 5 feet from the May 1980 levels. (USGS)

Alternative E ammonia feedstock

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lentz, M.J.; Wright, R.A.

1999-07-01

Power plants are using more Ammonia for increasing precipitator and baghouse efficiency, for SCR and SNCR processes, and for controlling acid stack plumes and dewpoint corrosion. These simple systems inject ammonia and air into the furnace or the precipitator or baghouse inlet ductwork. The common feedstocks in use today are Anhydrous ammonia [NH{sub 3}] and Aqueous ammonia [NH{sub 4}OH], both defined as poison gases by US authorities and most Western nations. Storage and handling procedures for these products are strictly regulated. Wilhelm Environmental Technologies Inc. is developing use of solid, formed or prilled Urea [CO(NH{sub 2}){sub 2}] as the feedstock.more » When heated in moist air, Urea sublimes to ammonia [NH{sub 3}] and carbon dioxide [CO{sub 2}]. Urea is stored and handled without restrictions or environmental concerns. Urea is a more expensive feedstock than NH{sub 3}, but much less expensive than [NH{sub 4}OH]. The design, and operating results, of a pilot system at Jacksonville Electric St. John's River Plant [Unit 2] are described. The pilot plant successfully sublimed Urea up to 100 pounds/hour. Further testing is planned. Very large ammonia use may favor NH{sub 3}, but smaller quantities can be produced at attractive prices with Urea based ammonia systems. Storage costs are far less. Many fluidized-bed boilers can use pastille or solid urea metered directly into the existing cyclones for NO{sub x} control. This is more economical than aqueous ammonia or aqueous urea based technology.« less

The safety of St John's wort (Hypericum perforatum) in pregnancy and lactation: A systematic review of rodent studies.

PubMed

Avila, Catharine; Whitten, Dawn; Evans, Sue

2018-04-30

Herbal products are popular among women during the perinatal period. St John's wort (SJW), Hypericum perforatum, is a common remedy for mild depression, a problem prevalent in this population. Although the safety of herbal products must be investigated, ethical issues constrain intervention studies in humans. Hence, animal studies often inform clinical decisions. The objective of this study is to systematically review rodent studies assessing the safety of SJW during the perinatal period. A literature search to November 10, 2017, identified 10 rodent studies that met a priori inclusion criteria. Study quality was evaluated according to both the Systematic Review Centre for Laboratory animal Experimentation tool for assessing bias and recommendations for appropriate reporting of herbal medicine research. Significant methodological limitations were found in each of the studies reviewed. These limitations include the lack of botanical verification and omission of extract characterization, inadequate explanation of dosage rationale, and absence of bias limiting protocols. Critical appraisal with contemporary tools indicates that each of the reviewed studies lacks appropriate rigour, rendering the results unreliable. Despite this, these papers are used in the rationale for recommending or contraindicating SJW during pregnancy and lactation. Copyright © 2018 John Wiley & Sons, Ltd.

Storage, retrieval, and analysis of ST data

NASA Technical Reports Server (NTRS)

Albrecht, R.

1984-01-01

Space Telescope can generate multidimensional image data, very similar in nature to data produced with microdensitometers. An overview is presented of the ST science ground system between carrying out the observations and the interactive analysis of preprocessed data. The ground system elements used in data archival and retrieval are described and operational procedures are discussed. Emphasis is given to aspects of the ground system that are relevant to the science user and to general principles of system software development in a production environment. While the system being developed uses relatively conservative concepts for the launch baseline, concepts were developed to enhance the ground system. This includes networking, remote access, and the utilization of alternate data storage technologies.

A retrospective analysis of eye conditions among children attending St. John Eye Hospital, Hebron, Palestine.

PubMed

Banayot, Riyad G

2016-04-05

Eye diseases are important causes of medical consultations, with the spectrum varying in different regions. This hospital-based descriptive study aimed to determine the profile of childhood eye conditions at St. John tertiary Eye hospital serving in Hebron, Palestine. Files of all new patients less than 16 years old who presented to St. John Eye Hospital-Hebron, Palestine between January 2013 and December 2013 were retrospectively reviewed. Age at presentation, sex, and clinical diagnosis were extracted from medical records. Data were stored and analyzed using Wizard data analysis version 1.6.0 by Evan Miller. The Chi square test was used to compare variables and a p value of less than 0.05 was considered statistically significant. We evaluated the records of 1102 patients, with a female: male ratio of 1:1.1. Patients aged 0-5 years old were the largest group (40.2%). Refractive errors were the most common ocular disorders seen (31.6%), followed by conjunctival diseases (23.7%) and strabismus and amblyopia (13.8%). Refractive errors were recorded more frequently and statistically significant (p < 0.001) among (11-15) age group. Within the conjunctival diseases category, conjunctivitis and dry eyes was more prominent and statistically significant (p < 0.001) among the 6-10 year old age group. Within the strabismus and amblyopia category, convergent strabismus was more common and statistically significant among the youngest age group (0-5 years old). The most common causes of ocular morbidity are largely treatable or preventable. These results suggest the need for awareness campaigns and early intervention programs.

Regional Sediment Management Strategies for the Vicinity of St. Augustine Inlet, St. Johns County, Florida

DTIC Science & Technology

2016-07-01

period 1941 to 1957 resulted in the construction of a north sand-trap groin structure approxi- mately 1,880 ft in length and a 3,695 ft long southern...jetty structure . The inlet channel and associated structures are maintained by SAJ. The project includes an outer channel authorized to -16 ft mean...erosion, several homes had to be temporarily vacated for major repairs, and several structures were granted permits to construct temporary sea walls

POW/MIA Issues. Volume 3. Appendixes

DTIC Science & Technology

1994-01-01

RANDS Johansen Charles SSgt/AF- 4 July 52 TFRM A611 RMC B-29/Photo op Vernon 19124748 TFRS 91st Strat RANDM Recon RANDS Rivers Bernard SSgt/AF- 4 July 52...Pvt Bellar, Bennie E. RA14326111 Cpl Beller, James E. RA18333098 Pvt Bernard , Elton J RA18281438 Cpl Besemer, Robert L. RA16263944 Cpl Billigmeier... Bernard AF31378023 Airman 1st class Mooradian, Ara A0932011 Capt Moore, John G. A0886003 Capt Myers, Thomas E. 13136A Capt Nelson, Lawrence A. A02221692

Joint Force Quarterly. Issue 60, 1st Quarter 2011

DTIC Science & Technology

2011-01-01

John J. Church, D.M.A Internet Publications Editor Joanna E. Seich Design Nicholas Crawford and Marco Marchegiani, U.S. Government Printing Office...agency of the Federal Government . n d u p r e s s . n d u . e d u About the covers Front cover: Corporal Bethany Hess, USMC, assigned to the 3d Battalion...Crawford and Marco Marchegiani, U.S. Government Printing Office Printed in St. Louis, Missouri by NDU Press is the National Defense University’s

Congressional Oversight: The New Mortal Enemy of Military Justice

DTIC Science & Technology

2000-04-01

Ansell , supra note 18, at 3-4. In 1776, after drafting the new Articles of War, John Adams supported his nearly verbatim adoption of the British Articles...martial process by requiring reporting of all court-martial sentences to, and approval by, the Commander-in-Chief, the 18 See S.T. Ansell , Military...supra note 30, at 21. 32 See THE WORKS OF JOHN ADAMS (Charles Francis Adams , ed., 1850-1856), quoted in LINDLEY, supra note 15, at 42-43, n. 100. 33

Geological Carbon Sequestration Storage Resource Estimates for the Ordovician St. Peter Sandstone, Illinois and Michigan Basins, USA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnes, David; Ellett, Kevin; Leetaru, Hannes

The Cambro-Ordovician strata of the Midwest of the United States is a primary target for potential geological storage of CO2 in deep saline formations. The objective of this project is to develop a comprehensive evaluation of the Cambro-Ordovician strata in the Illinois and Michigan Basins above the basal Mount Simon Sandstone since the Mount Simon is the subject of other investigations including a demonstration-scale injection at the Illinois Basin Decatur Project. The primary reservoir targets investigated in this study are the middle Ordovician St Peter Sandstone and the late Cambrian to early Ordovician Knox Group carbonates. The topic of thismore » report is a regional-scale evaluation of the geologic storage resource potential of the St Peter Sandstone in both the Illinois and Michigan Basins. Multiple deterministic-based approaches were used in conjunction with the probabilistic-based storage efficiency factors published in the DOE methodology to estimate the carbon storage resource of the formation. Extensive data sets of core analyses and wireline logs were compiled to develop the necessary inputs for volumetric calculations. Results demonstrate how the range in uncertainty of storage resource estimates varies as a function of data availability and quality, and the underlying assumptions used in the different approaches. In the simplest approach, storage resource estimates were calculated from mapping the gross thickness of the formation and applying a single estimate of the effective mean porosity of the formation. Results from this approach led to storage resource estimates ranging from 3.3 to 35.1 Gt in the Michigan Basin, and 1.0 to 11.0 Gt in the Illinois Basin at the P10 and P90 probability level, respectively. The second approach involved consideration of the diagenetic history of the formation throughout the two basins and used depth-dependent functions of porosity to derive a more realistic spatially variable model of porosity rather than applying a single estimate of porosity throughout the entire potential reservoir domains. The second approach resulted in storage resource estimates of 3.0 to 31.6 Gt in the Michigan Basin, and 0.6 to 6.1 Gt in the Illinois Basin. The third approach attempted to account for the local-scale variability in reservoir quality as a function of both porosity and permeability by using core and log analyses to calculate explicitly the net effective porosity at multiple well locations, and interpolate those results throughout the two basins. This approach resulted in storage resource estimates of 10.7 to 34.7 Gt in the Michigan Basin, and 11.2 to 36.4 Gt in the Illinois Basin. A final approach used advanced reservoir characterization as the most sophisticated means to estimating storage resource by defining reservoir properties for multiple facies within the St Peter formation. This approach was limited to the Michigan Basin since the Illinois Basin data set did not have the requisite level of data quality and sampling density to support such an analysis. Results from this approach led to storage resource estimates of 15.4 Gt to 50.1 Gt for the Michigan Basin. The observed variability in results from the four different approaches is evaluated in the context of data and methodological constraints, leading to the conclusion that the storage resource estimates from the first two approaches may be conservative, whereas the net porosity based approaches may over-estimate the resource.« less

77 FR 67665 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-13

... Mill, Jesus Barcinas Rd., Merizo, 12000973 INDIANA Porter County Meyer, Dr. John and Gerda, House, 360..., 345 Main St., East Aurora, 12000981 Herkimer County Perry, Stuart and William Swezey Houses, 7541...

36 CFR 7.46 - Virgin Islands Coral Reef National Monument.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Hurricane Hole and blue runner (hardnose) line fishing in the area south of St. John. The Superintendent... landfall of the hurricane to 48 hours following passage of the hurricane. (5) No lines or ropes shall be...

36 CFR 7.46 - Virgin Islands Coral Reef National Monument.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Hurricane Hole and blue runner (hardnose) line fishing in the area south of St. John. The Superintendent... landfall of the hurricane to 48 hours following passage of the hurricane. (5) No lines or ropes shall be...

36 CFR 7.46 - Virgin Islands Coral Reef National Monument.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Hurricane Hole and blue runner (hardnose) line fishing in the area south of St. John. The Superintendent... landfall of the hurricane to 48 hours following passage of the hurricane. (5) No lines or ropes shall be...

78 FR 62831 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

..., SEC, dated July 29, 2013 (``FSI''); Howard Spindel, Senior Managing Director, and Cassondra E. Joseph..., Securities Arbitration Clinic of St. John's University School of Law, to Elizabeth M. Murphy, Secretary, SEC...

77 FR 45373 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-31

..., 12000527 Mercer County Roebling's, John A., Sons Company, Trenton, N.J., Block 3, Bounded by Hamilton Ave... St., Yankton, 12000536 VIRGINIA Arlington County Georgetown Pike, From DC/VA boundary at Chain Bridge...

Feasibility and Effectiveness of Memory Specificity Training in Depressed Outpatients: A Pilot Study.

PubMed

Eigenhuis, Eline; Seldenrijk, Adrie; van Schaik, Anneke; Raes, Filip; van Oppen, Patricia

2017-01-01

Research has shown that depressed patients suffer from reduced autobiographical memory specificity (rAMS). This cognitive phenomenon is associated with the maintenance and recurrence of depressive symptoms. This pilot study aims to investigate the feasibility and effectiveness of a relatively new group-based intervention (Memory Specificity Training; MeST) that aims to reduce rAMS in an outpatient setting. Twenty-six depressed outpatients received MeST during the waiting period prior to psychotherapy. The Client Satisfaction Questionnaire (CSQ-8) was used to measure client satisfaction after the training. The Autobiographical Memory Test (AMT) was used to measure memory specificity before and after the training. Depressive symptoms were measured using the Beck Depression Inventory (BDI-II) and the Montgomery Asberg Depression Rating Scale (MADRS), before and after the training, and at a 3-month follow-up. Participants as well as trainers were positive about the use of MeST. Participants also showed an increase in memory specificity and a decrease in depressive symptoms. This study suggests that MeST is feasible in an outpatient setting, that it increases autobiographical memory specificity and that it may decrease depressive symptoms. A randomized controlled trial is recommended to examine MeST and its effects on autobiographical memory specificity, depressive symptoms and depressive relapse more extensively. Copyright © 2015 John Wiley & Sons, Ltd. Key Practitioner Message: Research suggests that modification of rAMS can advance recovery and reduce the chance of developing a depression relapse. However, most existing psychotherapies for depression do not include these specific interventions. This is the first study to show that MeST in an outpatient setting is feasible and can lead to an increase in autobiographical memory specificity and that it may decrease depressive symptoms. A larger scale randomized controlled trial is required to examine whether the addition of MeST to care as usual decreases depressive symptoms more effectively than care as usual without MeST, and to examine whether subgroups of patients benefit specifically from this intervention (e.g. patients with more severely decreased memory specificity). Copyright © 2015 John Wiley & Sons, Ltd.

Health and health care in the U.S. Virgin Islands: challenges and perceptions.

PubMed

Callwood, Gloria B; Campbell, Doris; Gary, Faye; Radelet, Michael L

2012-01-01

This research was designed to discover how residents of the United States Virgin Islands think about their health, health status, health problems, and the quality of the health care delivery system. Six focus groups were organized--one for males and one for females on each of the largest, islands (St. Thomas, St. Croix, and St. John). Results indicated that Virgin Islanders see a large role for personal responsibility in achieving and maintaining good health, although there are cultural and economic barriers that prevent taking full advantage of available health services. Residents are especially concerned about privacy and threats to confidentiality of patient information that could occur among professionals.

77 FR 60135 - St. Johns National Wildlife Refuge, FL; Final Comprehensive Conservation Plan and Finding of No...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-02

... possible to benefit refuge wildlife. Under Alternative C, we will expand management of wood storks and..., hiking, and bicycling. Bicycling that does not support appropriate and compatible uses, such as mountain...

Time to Talk: 5 Things to Know about St. John's Wort and Depression

MedlinePlus

... What You Should Know About the Science Behind Depression and Complementary Health Approaches Share: Depression is a ... links Facebook Read our disclaimer about external links YouTube Read our disclaimer about external links Google+ Read ...

Region-dependent hamstrings activity in Nordic hamstring exercise and stiff-leg deadlift defined with high-density electromyography.

PubMed

Hegyi, A; Péter, A; Finni, T; Cronin, N J

2018-03-01

Recent studies suggest region-specific metabolic activity in hamstring muscles during injury prevention exercises, but the neural representation of this phenomenon is unknown. The aim of this study was to examine whether regional differences are evident in the activity of biceps femoris long head (BFlh) and semitendinosus (ST) muscles during two common injury prevention exercises. Twelve male participants without a history of hamstring injury performed the Nordic hamstring exercise (NHE) and stiff-leg deadlift (SDL) while BFlh and ST activities were recorded with high-density electromyography (HD-EMG). Normalized activity was calculated from the distal, middle, and proximal regions in the eccentric phase of each exercise. In NHE, ST overall activity was substantially higher than in BFlh (d = 1.06 ± 0.45), compared to trivial differences between muscles in SDL (d = 0.19 ± 0.34). Regional differences were found in NHE for both muscles, with different proximal-distal patterns: The distal region showed the lowest activity level in ST (regional differences, d range = 0.55-1.41) but the highest activity level in BFlh (regional differences, d range = 0.38-1.25). In SDL, regional differences were smaller in both muscles (d range = 0.29-0.67 and 0.16-0.63 in ST and BFlh, respectively) than in NHE. The use of HD-EMG in hamstrings revealed heterogeneous hamstrings activity during typical injury prevention exercises. High-density EMG might be useful in future studies to provide a comprehensive overview of hamstring muscle activity in other exercises and high-injury risk tasks. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Astronomy Behind Enemy Lines in Colonial North America: John Winthrop's Observations of the Transits of Venus

NASA Astrophysics Data System (ADS)

Schechner, S. J.

2005-12-01

In May 1761, John Winthrop packed up two students, an excellent clock, an octant, and two telescopes, and embarked for Newfoundland to observe the Transit of Venus. Winthrop's departure was hasty. Only days before had the President and Fellows of Harvard College approved Professor Winthrop's request to take the college apparatus behind enemy lines to serve the cause of science, and Winthrop knew he had no time to waste if he were to reach Newfoundland and properly calibrate his equipment before the Transit. Winthrop's expedition to St. John's, Newfoundland was nothing short of remarkable. His goal was to help determine the distance from the Earth to the Sun, and he was the only North American astronomer fit for this project. His expedition was financed by the General Court of Massachusetts, which also secured him safe passage across enemy lines during the French and Indian War. Winthrop's trip to St. John's was a major achievement for colonial astronomy, but he was unhappy with his observations and so looked forward to a second chance to observe a transit in 1769. Benjamin Franklin urged him to go to Lake Superior. Planning for that transit was thwarted, however, by two events: (1) the loss of nearly all of Harvard's apparatus in a fire of 1764; and (2) pre-Revolutionary politics in the American colonies. In the end, Winthrop was forced to content himself with first-class observations with new instruments in Cambridge.

Assessment of Zr-Fe-V getter alloy for gas-gap heat switches

NASA Technical Reports Server (NTRS)

Prina, M.; Kulleck, J. G.; Bowman, R. C., Jr.

2000-01-01

A commercial Zr-V-Fe alloy (i.e., SAES Getters trade name alloy St-172) has been assessed as reversible hydrogen storage material for use in actuators of gas gap heat switches. Two prototype actuators containing the SAES St-172 material were built and operated for several thousand cycles to evaluate performance of the metal hydride system under conditions simulating heat switch operation.

Brooks Grease Service, Inc. - Clean Water Act Public Notice

EPA Pesticide Factsheets

The EPA is providing notice of a proposed Administrative Penalty Assessment against Forterra Concrete Products, Inc., a business located at 511 E. John Carpenter Freeway, Irving, TX, 75062, for alleged violations at its facility located at 23600 W. 40th St

77 FR 77085 - Changes in Flood Hazard Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-31

... Docket Town of Tea (11-08- The Honorable John City Hall, 600 East June 18, 2012 460143 No.: B-1252). 0969P). Lawler, Mayor, Town 1st Street, Tea, SD of Tea, P.O. Box 57064. 128, Tea, SD 57064. (Catalog of...

Forterra Concrete Products, Inc. - Clean Water Act Public Notice

EPA Pesticide Factsheets

The EPA is providing notice of a proposed Administrative Penalty Assessment against Forterra Concrete Products, Inc., a business located at 511 E. John Carpenter Freeway, Irving, TX, 75062, for alleged violations at its facility located at 23600 W. 40th St

Low latency network and distributed storage for next generation HPC systems: the ExaNeSt project

NASA Astrophysics Data System (ADS)

Ammendola, R.; Biagioni, A.; Cretaro, P.; Frezza, O.; Lo Cicero, F.; Lonardo, A.; Martinelli, M.; Paolucci, P. S.; Pastorelli, E.; Pisani, F.; Simula, F.; Vicini, P.; Navaridas, J.; Chaix, F.; Chrysos, N.; Katevenis, M.; Papaeustathiou, V.

2017-10-01

With processor architecture evolution, the HPC market has undergone a paradigm shift. The adoption of low-cost, Linux-based clusters extended the reach of HPC from its roots in modelling and simulation of complex physical systems to a broader range of industries, from biotechnology, cloud computing, computer analytics and big data challenges to manufacturing sectors. In this perspective, the near future HPC systems can be envisioned as composed of millions of low-power computing cores, densely packed — meaning cooling by appropriate technology — with a tightly interconnected, low latency and high performance network and equipped with a distributed storage architecture. Each of these features — dense packing, distributed storage and high performance interconnect — represents a challenge, made all the harder by the need to solve them at the same time. These challenges lie as stumbling blocks along the road towards Exascale-class systems; the ExaNeSt project acknowledges them and tasks itself with investigating ways around them.

Black cohosh with or without St. John's wort for symptom-specific climacteric treatment--results of a large-scale, controlled, observational study.

PubMed

Briese, Volker; Stammwitz, Ute; Friede, Michael; Henneicke-von Zepelin, Hans-Heinrich

2007-08-20

To evaluate usage pattern, effectiveness and safety of Black cohosh alone or in fixed combination with St. John's wort on menopausal symptoms in general clinical practice. Prospective, controlled open-label observational study of 6141 women at 1287 outpatient gynecologists in Germany. Subjects were treated with recommended doses of study therapies, with treatment chosen by the participating physicians. Patients were followed up for 6 months, optionally 12 months. The primary effectiveness variable was Menopause Rating Scale (MRS) subscore PSYCHE at Month 3 evaluated by ANCOVA. The treatment groups were comparable at baseline, excepting the main MRS score and the PSYCHE score (monotherapy: 0.31+/-0.22; combination therapy: 0.42+/-0.23). Reductions from baseline were seen with both regimens for all variables. The changes in the primary variable remained significantly different between groups (p<0.001) when adjusted for differences at baseline with the combination therapy being superior: from 0.37 (adjusted) to 0.25 (95% CI: 0.24-0.25) and 0.23 (95% CI: 0.22-0.23) at Month 3 in the monotherapy and combination-therapy groups, respectively. The improvement by both therapies was maintained at 6 and 12 months. The rate of possibly treatment-related adverse events was 0.16%, all non-serious. The results support the effectiveness and tolerability profiles of two Black cohosh-based therapies for menopausal symptoms in general practice. They were used differentially: the monotherapy for neurovegetative symptoms, the combination for patients with more pronounced mood complaints. The fixed combination of Black cohosh and St. John's wort was superior to Black cohosh alone in alleviating climacteric mood symptoms.

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 5. Complementary and Alternative Medicine Treatments.

PubMed

Ravindran, Arun V; Balneaves, Lynda G; Faulkner, Guy; Ortiz, Abigail; McIntosh, Diane; Morehouse, Rachel L; Ravindran, Lakshmi; Yatham, Lakshmi N; Kennedy, Sidney H; Lam, Raymond W; MacQueen, Glenda M; Milev, Roumen V; Parikh, Sagar V

2016-09-01

The Canadian Network for Mood and Anxiety Treatments (CANMAT) conducted a revision of the 2009 guidelines by updating the evidence and recommendations. The scope of the 2016 guidelines remains the management of major depressive disorder (MDD) in adults, with a target audience of psychiatrists and other mental health professionals. Using the question-answer format, we conducted a systematic literature search focusing on systematic reviews and meta-analyses. Evidence was graded using CANMAT-defined criteria for level of evidence. Recommendations for lines of treatment were based on the quality of evidence and clinical expert consensus. "Complementary and Alternative Medicine Treatments" is the fifth of six sections of the 2016 guidelines. Evidence-informed responses were developed for 12 questions for 2 broad categories of complementary and alternative medicine (CAM) interventions: 1) physical and meditative treatments (light therapy, sleep deprivation, exercise, yoga, and acupuncture) and 2) natural health products (St. John's wort, omega-3 fatty acids; S-adenosyl-L-methionine [SAM-e], dehydroepiandrosterone, folate, Crocus sativus, and others). Recommendations were based on available data on efficacy, tolerability, and safety. For MDD of mild to moderate severity, exercise, light therapy, St. John's wort, omega-3 fatty acids, SAM-e, and yoga are recommended as first- or second-line treatments. Adjunctive exercise and adjunctive St. John's wort are second-line recommendations for moderate to severe MDD. Other physical treatments and natural health products have less evidence but may be considered as third-line treatments. CAM treatments are generally well tolerated. Caveats include methodological limitations of studies and paucity of data on long-term outcomes and drug interactions. © The Author(s) 2016.

Reduction of high-affinity beta2-adrenergic receptor binding by hyperforin and hyperoside on rat C6 glioblastoma cells measured by fluorescence correlation spectroscopy.

PubMed

Prenner, Lars; Sieben, Anne; Zeller, Karin; Weiser, Dieter; Häberlein, Hanns

2007-05-01

Beta-adrenergic receptors (beta-AR) are potential targets for antidepressants. Desensitization and downregulation of beta-AR are discussed as possible modes of action for antidepressants. We have investigated the effects of hyperforin and hyperoside, compounds with potentially antidepressant activity from St. John's Wort, on the binding behavior and dynamics of beta2-AR in living rat C6 glioblastoma cells, compared to desipramine (desmethylimipramine; DMI) by means of fluorescence correlation spectroscopy (FCS) and fluorescence microscopy. FCS-binding studies with the fluorescently labeled ligand Alexa532-noradrenaline (Alexa532-NA) binding to beta2-AR of C6 cells showed a significant reduction in total beta2-AR binding after preincubation with hyperforin and hyperoside for 3 days, respectively, which was also found for DMI. This was mainly observed in high-affinity receptor-ligand complexes with hindered lateral mobility (D2 = 1.1 (+/-0.4) microm2/s) in the biomembrane. However, internalization of beta2-AR was found neither in z-scans of these C6 cells nor in HEK 293 cells stably transfected with GFP-tagged beta2-adrenergic receptors (beta2AR-GFP) after incubation up to 6 days with either DMI, hyperforin, or hyperoside. Thus, under these conditions reduction of beta2-AR binding was not mediated by receptor internalization. Additionally, preincubation of C6 cells with DMI, hyperforin, and hyperoside led to a loss of second messenger cAMP after beta2-adrenergic stimulating conditions with terbutaline. Our current results indicate that hyperforin and hyperoside from St. John's Wort, as well as DMI, reduce beta2-adrenergic sensitivity in C6 cells, emphasizing the potential usefulness of St. John's Wort dry extracts in clinical treatment of depressive symptoms.

Hyperforin is a modulator of inducible nitric oxide synthase and phagocytosis in microglia and macrophages.

PubMed

Kraus, Birgit; Wolff, Horst; Elstner, Erich F; Heilmann, Jörg

2010-06-01

Upon activation, microglia, the immunocompetent cells in the brain, get highly phagocytic and release pro-inflammatory mediators like nitric oxide (NO). Excessive NO production is pivotal in neurodegenerative disorders, and there is evidence that abnormalities in NO production and inflammatory responses may at least support a range of neuropsychiatric disorders, including depression. Although extracts of St. John's wort (Hypericum perforatum L.) have been used for centuries in traditional medicine, notably for the treatment of depression, there is still considerable lack in scientific knowledge about the impact on microglia. We used N11 and BV2 mouse microglia, as well as RAW 264.7 macrophages to investigate the effects of St. John's wort extract and constituents thereof on NO production Moreover, flow cytometry and fluorescence microscopy were employed to analyze the influence on phagocytosis, transcription factor activation states, and cell motility. We found that extracts of St. John's wort efficiently suppress lipopolysaccharide-induced NO release and identified hyperforin as the responsible compound, being effective at concentrations between 0.25 and 0.75 microM. The reduced NO production was mediated by diminished inducible nitric oxide synthase expression on the mRNA and protein level. In addition, at similar concentrations, hyperforin reduced zymosan phygocytosis to 20-40% and putatively acted by downregulating the CD206 macrophage mannose receptor and modulation of cell motility. We found that the observed effects correlate with a suppression of the activated state of Nf-kappaB and phospho-CREB, while c-JUN, STAT1, and HIF-1alpha activity and cyclooxygenase-2 expression remained unaffected by hyperforin. These results reveal that hyperforin influences pro-inflammatory and immunological responses of microglia that are involved in the progression of neuropathologic disorders.

Description of the ambulance services participating in the Aus-ROC Australian and New Zealand out-of-hospital cardiac arrest Epistry.

PubMed

Beck, Ben; Bray, Janet E; Smith, Karen; Walker, Tony; Grantham, Hugh; Hein, Cindy; Thorrowgood, Melanie; Smith, Anthony; Inoue, Madoka; Smith, Tony; Dicker, Bridget; Swain, Andy; Bosley, Emma; Pemberton, Katherine; McKay, Michael; Johnston-Leek, Malcolm; Cameron, Peter; Perkins, Gavin D; Finn, Judith

2016-12-01

The present study aimed to describe and examine similarities and differences in the current service provision and resuscitation protocols of the ambulance services participating in the Aus-ROC Australian and New Zealand out-of-hospital cardiac arrest (OHCA) Epistry. Understanding these similarities and differences is important in identifying ambulance service factors that might explain regional variation in survival of OHCA in the Aus-ROC Epistry. A structured questionnaire was completed by each of the ambulance services participating in the Aus-ROC Epistry. These ambulance services were SA Ambulance Service, Ambulance Victoria, St John Ambulance Western Australia, Queensland Ambulance Service, St John Ambulance NT, St John New Zealand and Wellington Free Ambulance. The survey aimed to describe ambulance service and dispatch characteristics, resuscitation protocols and details of cardiac arrest registries. We observed similarities between services with respect to the treatment of OHCA and dispatch systems. Differences between services were observed in the serviced population; the proportion of paramedics with basic life support, advanced life support or intensive care training skills; the number of OHCA cases attended; guidelines related to withholding or terminating resuscitation attempts; and the variables that might be used to define 'attempted resuscitation'. All seven participating ambulance services were noted to have existing OHCA registries. There is marked variation between ambulance services currently participating in the Aus-ROC Australian and New Zealand OHCA Epistry with respect to workforce characteristics and key variable definitions. This variation between ambulance services might account for a proportion of the regional variation in survival of OHCA. © 2016 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

Cost-Effective, Ultra-Sensitive Groundwater Monitoring for Site Remediation and Management

DTIC Science & Technology

2015-05-01

Example anion concentrations in groundwater used for feasibility studies. ................... 30 Table 5. Compounds screened in the laboratory for IS2...phase extraction ST storage tank SVOC semivolatile organic compound TCE trichloroethene TPH total petroleum hydrocarbon USEPA U.S. Environmental...Protection Agency UST underground storage tank V volt VOA volatile organic analysis VOC volatile organic compound Technical material

77 FR 11527 - Bluewater Gas Storage, LLC; Notice of Intent To Prepare an Environmental Assessment for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-27

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP12-51-000] Bluewater Gas Storage, LLC; Notice of Intent To Prepare an Environmental Assessment for the Proposed St. Clair River Crossing Replacement Project, Request for Comments on Environmental Issues, and Notice of Onsite Environmental Review The staff of the Federal...

Clinical outcomes of a stepped care program for borderline personality disorder.

PubMed

Laporte, Lise; Paris, Joel; Bergevin, Tanya; Fraser, Ronald; Cardin, Jean-François

2018-04-30

This study examines the clinical outcomes of two clinics for borderline personality disorder (BPD) in a naturalistic setting, offering a stepped care model with both short-term (ST) treatment lasting 12 weeks and extended care (EC) up to 24 months. A total of 479 patients attending the ST clinic and 145 attending the EC clinic were assessed on depression, impulsivity, self-esteem, emotion dysregulation, substance abuse, self-harm and suicidality. There were significant reductions in all symptoms in both clinics with the exception that substance abuse was only reduced in the EC clinic. On all symptoms, no significant differences in magnitude of changes were observed between patients who stayed in EC clinic for 6-12 months in comparison to those who stayed for 18-24 months. These results support the concept that for the majority of patients with BPD, brief treatment can be effective. While some patients still need longer treatment, the results are encouraging for brief treatment as a first step for the majority of patients with BPD. While this study adds to the weight of evidence to support ST interventions for patients with BPD, further research using a control group is needed. Copyright © 2018 John Wiley & Sons, Ltd. Copyright © 2018 John Wiley & Sons, Ltd.

Effects of hamstring stretching on passive muscle stiffness vary between hip flexion and knee extension maneuvers.

PubMed

Miyamoto, N; Hirata, K; Kanehisa, H

2017-01-01

The purpose of this study was to examine whether the effects of hamstring stretching on the passive stiffness of each of the long head of the biceps femoris (BFl), semitendinosus (ST), and semimembranosus (SM) vary between passive knee extension and hip flexion stretching maneuvers. In 12 male subjects, before and after five sets of 90 s static stretching, passive lengthening measurements where knee or hip joint was passively rotated to the maximal range of motion (ROM) were performed. During the passive lengthening, shear modulus of each muscle was measured by ultrasound shear wave elastography. Both stretching maneuvers significantly increased maximal ROM and decreased passive torque at a given joint angle. Passive knee extension stretching maneuver significantly reduced shear modulus at a given knee joint angle in all of BFl, ST, and SM. In contrast, the stretching effect by passive hip flexion maneuver was significant only in ST and SM. The present findings indicate that the effects of hamstring stretching on individual passive muscles' stiffness vary between passive knee extension and hip flexion stretching maneuvers. In terms of reducing the muscle stiffness of BFl, stretching of the hamstring should be performed by passive knee extension rather than hip flexion. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

A matter of scale: damage from Hurricane Hugo (1989) to U.S. Virgin Islands reefs at the colony, community and whole reef level

USGS Publications Warehouse

Rogers, Caroline S.

1993-01-01

Studies at Buck Island Reef National Monument (St. Croix) and Virgin Islands National Park (St. John) by scientists in the U.S. National Park Service Coral Reef Assessment Program re- vealed the effects of Humcane Hugo on individual coral species, community parameters, and overall reef structure. Effects of the storm varied with depth, coral species, location relative to the storm path, character of the pre-storm communities, and ecological history. Live coral cover, initially less than 30% at all sites, dropped by 40 to 73%. Cover by the dominant species Montastrea annularis de- clined about 35% on the St. John reefs. At Buck Island, Acropora palmata cover, already reduced from 85% to 5% by white band disease and storms, fell to 0.8% after Hugo. Some areas on the south side of Buck Island were reduced to rubble pave- ment while other areas escaped serious damage. Data from cores at Buck Island reveal the influence of wave energy and storm frequency on overall reef character. Patchiness and variation in the responses of different species, zones, and entire reefs to the storm suggest that assessment of long-term trends in reef structure and composition requires analysis of changes at permanent study sites distributed over large areas.

Effect of surgical periodontal treatment associated to antimicrobial photodynamic therapy on chronic periodontitis: A randomized controlled clinical trial.

PubMed

Martins, Sérgio H L; Novaes, Arthur B; Taba, Mario; Palioto, Daniela B; Messora, Michel R; Reino, Danilo M; Souza, Sérgio L S

2017-07-01

This randomized controlled clinical trial evaluated the effects of an adjunctive single application of antimicrobial photodynamic therapy (aPDT) in Surgical Periodontal Treatment (ST) in patients with severe chronic periodontitis (SCP). In a split-mouth design, 20 patients with SCP were treated with aPDT+ST (Test Group, TG) or ST only (Control Group, CG). aPDT was applied in a single episode, using a diode laser and a phenothiazine photosensitizer. All patients were monitored until 90 days after surgical therapy. Levels of 40 subgingival species were measured by checkerboard DNA-DNA hybridization at baseline, 60 and 150 days. Clinical and microbiological parameters were evaluated. In deep periodontal pockets depth (PPD ≥5 mm), Test Group presented a significantly higher decrease in PPD than Control Group at 90 days after surgical therapy (p < .05). Test Group also demonstrated significantly less periodontal pathogens of red complex (Treponema denticola) (p < .05). A single episode of aPDT used in adjunct to open flap debridement of the root surface in the surgical treatment of SCP: i) significantly improved clinical periodontal parameters; ii) eliminates periodontal pathogens of the red complex more effectively (NCT02734784). © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

The Solutions Data Base Component of the Water Pollution Abatement Subsystem (WPAS) of the Pollution Abatement Management System. (PAMS).

DTIC Science & Technology

1981-04-01

Facilities EngineerATTN: DAEN-MPC Fitzs ;mons Amy Medical Center ATTN: DAEN-PE Army Instl. and Major Activities (CONuS; waiter Reed Army Medical center ATTN...S)St. Paul Fort Sheridan 21st Support ComandTulsa Fort Stewart4 Vicksburg Fort Wainmright AN: AREA (5) Walls Walla Vancouver Bks. Wilmington US Am...ABG/DEEE Patrick AFB, FL 32925 ATTN: XRQ ’ C Bandy, John T. The Solutions Data Base component of the Water Pollution Abatement Subsystem (WPAS) of the

Proceedings of the Meeting of the Coastal Engineering Research Board (45th) Held in Fairbanks and Homer, Alaska on 14-16 May 1986.

DTIC Science & Technology

1986-12-01

65 THE COASTAL COMMUNITY IN THE STATE OF ALASKA Dr. John B. Olson, DOT and PUBLIC FACILITIES ..................... 69 ST. GEORGE HARBOR LOW...WRSC-D) 0930 - 0945 COFFEE BREAK 0945 - 1030 Continuation of Chief’s Initiatives BG Patrick J. Kelly (DAEN-CWZ) 1030 - 1100 The Coastal Community in...weather permit- ting, they just tell them to slow down till a berth is available. 68 THE COASTAL COMMUNITY IN THE STATE OF ALASKA Dr. John B. Olson Special

Loss of PTEN as a Predictive Biomarker of Response to Lithium Chloride, A Potential Targeted Treatment for Breast Cancer

DTIC Science & Technology

2013-11-01

COVERED (From - To) 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER...The grant was awarded on June 1st 2010. Dr. Higgins graduated from her Oncology Fellowship Program in Johns Hopkins Hospital on June 30th and... grant to support Dr. Higgins as she continued this work was submitted and processed in June 2010 in anticipation of this move. Johns Hopkins University

St. John's Wort (Hypericum Perforatum) and Pregnancy

MedlinePlus

... al. 1999. Assessing the risks and benefits of herbal medicine: An overview of scientific evidence. Altern Ther Health ... Nordeng H and Havnen GC. 2004. Use of herbal drugs in pregnancy: a survey ... herbs used in alternative medicine. J Assist Reprod Genet 16(2):87-91. ...

The Ideas of Hector St. John de Crevecoeur and the Early Quest to Define American Character

ERIC Educational Resources Information Center

Schultz, Frederick Marshall

1975-01-01

The primary purpose of this paper was to consider the ideas which Crevecoeur brought to bear in his attempt to uncover the character of the American man, newly settled on the eighteenth century frontier. (Author/RK)

"In Honor of Excellence."

ERIC Educational Resources Information Center

Hughes, Anna May

1983-01-01

Spotlights seven outstanding secondary school theatre programs and their directors: Frank Bluestein, Germantown, TN; John Steele, Plano, TX; Joe Juliano, Hamden, CT; Jack Parkhurst, Ralston, NE; Robert Geuder (Thomas Jefferson High School) Cedar Rapids, IA; Judith Rethwisch (Affton High School) St. Louis, MO; and Henry Wicke (Packer Collegiate…

The “Empty Chairs” Approach to Learning: Simulation-Based Train the Trainer Program in Mzuzu, Malawi

PubMed Central

Sigalet, Elaine; Wishart, Ian; Lufesi, Norman; Haji, Faizal

2017-01-01

Together, a group of Canadian colleagues from St. John's, Newfoundland, Calgary, Alberta (some via Doha) and London, Ontario introduced the first Train the Trainer in Simulation-Based Learning (TTT-SBL) program in Mzuzu Central Hospital and Mzuzu University in Malawi. The team led by Elaine Sigalet (Doha) and consisting of Ian Wishart (Calgary), Faizal Haji (London) and Adam Dubrowski (St. John's) was invited to Malawi by Norman Lufesi to conduct a two-day TTT-SBL course for facilitators who teach an Emergency Triage, Assessment and Treatment (ETAT) plus Trauma course. The following technical report describes this course.  All trainees-facilitators who took part in the first iteration of the TTT-SBL course were asked to participate in teaching an ETAT course and modify it to include elements of simulation. The new format of ETAT resulted in a reduction of time necessary to conduct the course from four days (based on historical data) to 2.5 days. PMID:28580202

Soul sisters: the St. John and Raynard nurses in nineteenth century London.

PubMed

Williamson, L

1996-01-01

This paper uses the archives of the St John's training institution for nurses and the Raynard Mission to determine the extent to which cultural images and specialised space defined and drove the nursing profession in nineteenth and early twentieth century London. Emphasis is placed upon image and rhetoric, both sacred and secular, and the way the two combined to define the 'ideal' Victorian woman and nursing in the nineteenth and early twentieth centuries, and the understanding and treatment of illness. Research to date suggests that through a process of rationalisation of biblical and socio-cultural rhetoric, a specialisation of space, symbolic and literal, abstract and real was created; this enabled women to work in a gendered enclave, the organisational structure and rhetoric of which paralleled that of nunneries or convents. And even as the 'secular' became dominant in medical attitudes and treatment, the 'sacred'aspect of nursing and the emphasis placed upon it as being a vocation remained strong.

Hyperforin promotes mitochondrial function and development of oligodendrocytes.

PubMed

Wang, Yanlin; Zhang, Yanbo; He, Jue; Zhang, Handi; Xiao, Lan; Nazarali, Adil; Zhang, Zhijun; Zhang, Dai; Tan, Qingrong; Kong, Jiming; Li, Xin-Min

2011-11-01

St. John's wort has been found to be an effective and safe herbal treatment for depression in several clinical trials. However, the underlying mechanism of its therapeutic effects is unclear. Recent studies show that the loss and malfunction of oligodendrocytes are closely related to the neuropathological changes in depression, which can be reversed by antidepressant treatment. In this study, we evaluated the effects of hyperforin, a major active component of St. John's wort, on the proliferation, development and mitochondrial function of oligodendrocytes. The study results revealed that hyperforin promotes maturation of oligodendrocytes and increases mitochondrial function without affecting proliferation of an oligodendrocyte progenitor cell line and neural stem/progenitor cells. Hyperforin also prevented mitochondrial toxin-induced cytotoxicity in an oligodendrocyte progenitor cell line. These findings suggest that hyperforin may stimulate the development and function of oligodendrocytes, which could be a mechanism of its effect in depression. Future in vitro and in vivo studies are required to further characterize the mechanisms of hyperforin. © 2011 The Authors. Journal of Neurochemistry © 2011 International Society for Neurochemistry.

Data from in situ Observations of Fish Traps Set by Fishermen in St. John Waters, U.S. Virgin Islands, 1992-94

USGS Publications Warehouse

Garrison, Virginia H.; Beets, Jim; Friedlander, Alan M.; Canty, Steven

2011-01-01

In order to estimate (1) the trapping pressure within Virgin Islands National Park (VINP) waters, (2) the effect of fish traps on park marine resources (both fishes and habitats), and (3) the effectiveness of park regulations in protecting marine resources, traps set by fishers were visually observed and contents censused in situ in 1992, 1993, and 1994, around St. John (U.S. Virgin Islands), within and outside of park waters. A total of 1,340 individual fish (56 species and 23 families) were identified and their lengths estimated for the 211 of 285 visually censused traps that contained fish. This dataset includes for each censused trap: location, depth, substrate/habitat, trap type and construction details, in or out of park waters, and species and estimated fork length (in centimeters) of each individual fish in a trap. Analysis and interpretation of this dataset are provided in previously published reports by the author.

Effects of coarse woody debris and its removal on a channel affected by the 1980 eruption of Mount St. Helens, Washington

Treesearch

Thomas E. Lisle

1995-01-01

Abstract - During the May 18, 1980, eruption of Mount St. Helens, Washington, a pyroclastic surge introduced large volumes of coarse woody debris (CWD) and fine grained sediment to Clearwater Creek, approximately 15 km northeast of the summit. Effects of controlled CWD removal on sediment storage, substrate, and pool frequency and volume were measured in four reaches,...

Carbon dynamics of forest in Washington, USA: 21st century projections based on climate-driven changes in fire regimes

Treesearch

Crystal L. Raymond; Donald McKenzie

2012-01-01

During the 21st century, climate-driven changes in fire regimes will be a key agent of change in forests of the U.S. Pacific Northwest (PNW). Understanding the response of forest carbon (C) dynamics to increases in fire will help quantify limits on the contribution of forest C storage to climate change mitigation and prioritize forest types for...

Biotechnological production of hyperforin for pharmaceutical formulation.

PubMed

Gaid, Mariam; Biedermann, Eline; Füller, Jendrik; Haas, Paul; Behrends, Sönke; Krull, Rainer; Scholl, Stephan; Wittstock, Ute; Müller-Goymann, Christel; Beerhues, Ludger

2018-05-01

Hyperforin is a major active constituent of Hypericum perforatum (St. John's wort). It has amazing pharmacological activities, such as antidepressant properties, but it is labile and difficult to synthesize. Its sensitivity and lipophilicity are challenges for processing and formulation. Its chemical complexity provokes approaches of biotechnological production and modification. Dedifferentiated H. perforatum cell cultures lack appropriate storage sites and hence appreciable hyperforin levels. Shoot cultures are capable of forming hyperforin but less suitable for biomass up-scaling in bioreactors. Roots commonly lack hyperforin but a recently established adventitious root line has been demonstrated to produce hyperforin and derivatives at promising levels. The roots also contained lupulones, the typical constituents of hop (Humulus lupulus). Although shear-sensitive, these root cultures provide a potential production platform for both individual compounds and extracts with novel combinations of constituents and pharmacological activities. Besides in vitro cultivation techniques, the reconstruction of hyperforin biosynthesis in microorganisms is a promising alternative for biotechnological production. The biosynthetic pathway is under study, with omics-technologies being increasingly implemented. These biotechnological approaches may not only yield hyperforin at reasonable productivity but also allow for modifications of its chemical structure and pharmacological profile. Copyright © 2017 Elsevier B.V. All rights reserved.

Clonal dissemination of multilocus sequence type ST15 KPC-2-producing Klebsiella pneumoniae in Bulgaria.

PubMed

Markovska, Rumyana; Stoeva, Temenuga; Schneider, Ines; Boyanova, Lyudmila; Popova, Valentina; Dacheva, Daniela; Kaneva, Radka; Bauernfeind, Adolf; Mitev, Vanyo; Mitov, Ivan

2015-10-01

A total of 36 consecutive clinical and two fecal-screening carbapenem-resistant Klebsiella pneumoniae isolates from two Bulgarian university hospitals (Varna and Pleven) were investigated. Susceptibility testing, conjugation experiments, and plasmid replicon typing were carried out. Beta-lactamases were characterized by isoelectric focusing, PCR, and sequencing. Clonal relatedness was investigated by RAPD and multilocus sequence typing (MLST). Most of the isolates demonstrated multidrug resistance profile. Amikacin and tigecycline retained good activity with susceptibility rates of 95 and 87%, respectively. The resistance rate to colistin was 63%. Six RAPD- and MLST-types were identified: the dominating MLST-type was ST15 (27 isolates), followed by ST76 (six isolates), and ST1350 (two isolates). ST101, ST258, and ST151 were detected once. All except one of the K. pneumoniae produced KPC-2, mostly in combination with CTX-M-15, while for one isolate (ST101) the enzymes OXA-48 and CTX-M-14 were found. All KPC-2-producing transconjugants revealed the presence of IncFII plasmid. The OXA-48- and CTX-M-14-producing isolate showed the presence of L/M replicon type. The dissemination of KPC-2-producing K.pneumoniae in Bulgaria is mainly due to the sustained spread of successful ST15 clone and to a lesser extent of ST76 clone. This is the first report of OXA-48 producing ST101 K. pneumoniae in Bulgaria. © 2015 APMIS. Published by John Wiley & Sons Ltd.

AdiosStMan: Parallelizing Casacore Table Data System using Adaptive IO System

NASA Astrophysics Data System (ADS)

Wang, R.; Harris, C.; Wicenec, A.

2016-07-01

In this paper, we investigate the Casacore Table Data System (CTDS) used in the casacore and CASA libraries, and methods to parallelize it. CTDS provides a storage manager plugin mechanism for third-party developers to design and implement their own CTDS storage managers. Having this in mind, we looked into various storage backend techniques that can possibly enable parallel I/O for CTDS by implementing new storage managers. After carrying on benchmarks showing the excellent parallel I/O throughput of the Adaptive IO System (ADIOS), we implemented an ADIOS based parallel CTDS storage manager. We then applied the CASA MSTransform frequency split task to verify the ADIOS Storage Manager. We also ran a series of performance tests to examine the I/O throughput in a massively parallel scenario.

Race, Ethnicity and Public Education.

ERIC Educational Resources Information Center

Hart, Philip S., Ed.

2002-01-01

This theme issue contains papers on race and ethnicity in public education: "Introduction" (Philip Hart); "Toward Democratic Education: The Importance of Culturally Responsive Leadership in 21st Century Schools" (Donna M. Davis); "Improving the Selection Process for Identifying Gifted Ethnic Minority Children" (John Dillard and Nettye R. Brazil);…

1st EVA - MS Smith and Grunsfeld during RSU changeout

NASA Image and Video Library

2000-01-26

STS103-331-013 (19-27 December 1999) --- Astronauts John M. Grunsfeld (right) and Steven L. Smith share space on the end of the remote manipulator system (RMS) as they change out gyroscopes, contained in rate sensor units (RSU) inside the Hubble Space Telescope (HST).

2. Photographic copy of original construction drawings, dated 30 September ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Photographic copy of original construction drawings, dated 30 September 1930, located at the John Gaw Meem Archive of Southwestern Architecture, Special Collections, University of New Mexico, Albuquerque, New Mexico. FIRST FLOOR PLAN. - St. Anthony's Orphanage, 1500 Indian School Road, Northwest, Albuquerque, Bernalillo County, NM

Department of Chemistry and Biochemistry - University of Maryland,

Science.gov Websites

Access Analytical Facilities? New Labs Catalyze Chemistry Learning Inclusive & Interdisciplinary New Collaborative Research New Labs Catalyze Chemistry Learning Inclusive & Interdisciplinary New Molecule Shows Author's profile esj-lab New Labs Catalyze Chemistry Learning The Edward St. John Learning and Teaching

New Course Design: Classification Schemes and Information Architecture.

ERIC Educational Resources Information Center

Weinberg, Bella Hass

2002-01-01

Describes a course developed at St. John's University (New York) in the Division of Library and Information Science that relates traditional classification schemes to information architecture and Web sites. Highlights include functional aspects of information architecture, that is, the way content is structured; assignments; student reactions; and…

Weapons Storage Area Survey of Munitions Storage Igloos at Medina Annex, San Antonio, Texas

DTIC Science & Technology

2013-11-13

School of Aerospace Medicine Occupational and Environmental Health Department Consultative Services Division/OEC 2510 Fifth St. Wright-Patterson AFB...a. Purpose: The United States Air Force School of Aerospace Medicine, Occupational and Environmental Health Department, Radiation Health ...Attachment 3 with other pertinent regulatory issues. c. Survey Personnel: (1) Health Physicist, Air Force Safety Center (2) Health Physicist, USAFSAM

Downregulation of β1 -adrenergic receptors in rat C6 glioblastoma cells by hyperforin and hyperoside from St John's wort.

PubMed

Jakobs, Daniel; Hage-Hülsmann, Anne; Prenner, Lars; Kolb, Christiane; Weiser, Dieter; Häberlein, Hanns

2013-06-01

While the use of St John's wort extracts as treatment for mild to moderate depression is well established the mode of action is still under investigation. Individual constituents of St John's wort extract were tested for possible effects on the β1 AR density and a subsequent change in downstream signalling in rat C6 glioblastoma cells. The effect of compounds from St John's wort extract on the downregulation of β1 -adrenergic receptor-GFP fusion proteins (β1 AR-green fluorescent protein (GFP)) of transfected rat C6 gliobastoma cells (C6-β1 AR-GFP) was investigated by means of confocal laser scanning microscopy (LSM). The influence on the lateral mobility of β1 AR-GFP in C6-β1 AR-GFP was investigated by fluorescence correlation spectroscopy. The formation of second messenger was determined by c-AMP-assay. Confocal LSM revealed that pretreatment of cells with 1 μm of hyperforin and hyperoside for 6 days, respectively, led to an internalization of β1 AR-GFP under non-stimulating conditions. Observation by fluorescence correlation spectroscopy showed two diffusion time constants for control cells, with τdiff1  = 0.78 ± 0.18 ms and τdiff2  = 122.53 ± 69.41 ms, similarly distributed. Pretreatment with 1 μm hyperforin or 1 μm hyperoside for 3 days did not alter the τdiff values but decreased the fraction of τdiff1 whereas the fraction of τdiff2 increased significantly. An elevated level of β1 AR-GFP with hindered lateral mobility was in line with β1 AR-GFP internalization induced by hyperforin and hyperoside, respectively. A reduced β1 -adrenergic responsiveness was assumed for C6 gliobastoma cells after pretreatment for 6 days with 1 μm of both hyperforin and hyperoside, which was confirmed by decreased cAMP formation of about 10% and 5% under non-stimulating conditions. Decrease in cAMP formation by 23% for hyperforin and 15% for hyperoside was more pronounced after stimulation with 10 μm dobutamine for 30 min. The treatment of C6 gliobastoma cells with hyperforin and hyperoside results in a reduced β1 AR density in the plasma membrane and a subsequent reduced downstream signalling. © 2013 Royal Pharmaceutical Society.

An evaluation of biomarkers of reproductive function and potential contaminant effects in Florida largemouth bass ( Micropterus salmoidesfloridanus) sampled from the St. Johns River.

PubMed

Sepúlveda, María S; Johnson, William E; Higman, John C; Denslow, Nancy D; Schoeb, Trenton R; Gross, Timothy S

2002-04-22

The objective of this study was to describe and compare several reproductive parameters for Florida largemouth bass (Micropterus salmoides floridanus) inhabiting the St. Johns River and exposed to different types and/or degrees of contamination. Welaka was selected as the reference site in this study because of its low urban and agricultural development, Palatka is in close proximity to a paper mill plant, the Green Cove site is influenced by marine shipping activities and Julington Creek site receives discharges of domestic wastewater and storm water runoff from recreational boating marinas. For this study, bass were sampled both prior to (September 1996) and during the spawning season (February 1997). In order to characterize chemical exposure, bass livers were analyzed for up to 90 trace organics and 11 trace metal contaminants. Reproductive parameters measured included gonadosomatic index (GSI), histological evaluation of gonads and plasma concentrations of vitellogenin (VTG), 17beta-estradiol (E2) and 11-ketotestosterone (11-KT). In general, the sum of organic chemicals was highest in livers from Palatka bass and bass from Green Cove and Julington Creek had higher hepatic concentrations of low molecular polycyclic aromatic hydrocarbons and polychlorinated biphenyls when compared to fish from Welaka. Metals were more variable across sites, with highest mean concentrations found in bass from either Julington Creek (Ag, As, Cr, Cu, Zn) or Welaka (Cd, Hg, Pb, Se, Tn). Female bass from Palatka and Green Cove had lower concentrations of E2, VTG and lower GSI in relation to Welaka. Males from Palatka and Green Cove showed comparable declines in 11-KT in relation to males from Julington Creek and GSI were decreased only in Palatka males. These results indicate a geographical trend in reproductive effects, with changes being most pronounced at the site closest to the paper mill (Palatka) and decreasing as the St. Johns River flows downstream. Since reproductive alterations were most evident in bass sampled from the site closest to the paper mill discharge, it is possible that exposure to these effluents might explain at least some of the results reported here. However, the presence of reproductive alterations in fish sampled at a considerable distance from the mill discharge (Green Cove, 40 km) would suggest exposure to chemicals released from sources other than the paper mill plant. It is clear that additional studies are needed to evaluate the potential impact of these reproductive changes in populations of Florida largemouth bass inhabiting the St. Johns River.

Herpetofaunal Inventories of the National Parks of South Florida and the Caribbean: Volume II. Virgin Islands National Park

USGS Publications Warehouse

Rice, Kenneth G.; Waddle, J. Hardin; Crockett, Marquette E.; Carthy, R.R.; Percival, H. Franklin

2005-01-01

Amphibian declines and extinctions have been documented around the world, often in protected natural areas. Concern for this alarming trend has focused attention on the need to document all species of amphibians that occur within U.S. National Parks and to search for any signs that amphibians may be declining. This study, an inventory of amphibian species in Virgin Islands National Park, was conducted from 2001 to 2003. The goals of the project were to create a georeferenced inventory of amphibian species, use new analytical techniques to estimate proportion of sites occupied by each species, look for any signs of amphibian decline (missing species, disease, die-offs, etc.), and to establish a protocol that could be used for future monitoring efforts. Several sampling methods were used to accomplish these goals. Visual encounter surveys and anuran vocalization surveys were conducted in all habitats throughout the park to estimate the proportion of sites or proportion of area occupied (PAO) by amphibian species in each habitat. Line transect methods were used to estimate density of some amphibian species and double observer analysis was used to refine counts based on detection probabilities. Opportunistic collections were used to augment the visual encounter methods for rare species. Data were collected during four sampling periods and every major trail system throughout the park was surveyed. All of the amphibian species believed to occur on St. John were detected during these surveys. One species not previously reported, the Cuban treefrog (Osteopilus septentrionalis), was also added to the species list. That species and two others (Eleutherodactylus coqui and Eleutherodactylus lentus) bring the total number of introduced amphibians on St. John to three. We detected most of the reptile species thought to occur on St. John, but our methods were less suitable for reptiles compared to amphibians. No amphibian species appear to be in decline at this time. We found no evidence of disease or of malformations. Our surveys provide a snapshot picture of the status of the amphibian species, so continued monitoring would be necessary to determine long-term trends, but several potential threats to amphibians were identified. Invasive species, especially the Cuban treefrog, have the potential to decrease populations of native amphibians. Introduced mammalian predators are also a potential threat, especially to the reptiles of St. John, and mammalian grazers might have indirect effects on amphibians and reptiles through habitat modification. Finally, loss of habitat to development outside the park boundary could harm some important populations of amphibians and reptiles on the island.

An evaluation of biomarkers of reproductive function and potential contaminant effects in Florida largemouth bass (Micropterus salmoides floridanus) sampled from the St. Johns River

USGS Publications Warehouse

Sepulveda, M.S.; Johnson, W.E.; Higman, J.C.; Denslow, N.D.; Schoeb, T.R.; Gross, T.S.

2002-01-01

The objective of this study was to describe and compare several reproductive parameters for Florida largemouth bass (Micropterus salmoides floridanus) inhabiting the St. Johns River and exposed to different types and/or degrees of contamination. Welaka was selected as the reference site in this study because of its low urban and agricultural development, Palatka is in close proximity to a paper mill plant, the Green Cove site is influenced by marine shipping activities and Julington Creek site receives discharges of domestic wastewater and storm water runoff from recreational boating marinas. For this study, bass were sampled both prior to (September 1996) and during the spawning season (February 1997). In order to characterize chemical exposure, bass livers were analyzed for up to 90 trace organics and 11 trace metal contaminants. Reproductive parameters measured included gonadosomatic index (GSI), histological evaluation of gonads and plasma concentrations of vitellogenin (VTG), 17??-estradiol (E2) and 11-ketotestosterone (11-KT). In general, the sum of organic chemicals was highest in livers from Palatka bass and bass from Green Cove and Julington Creek had higher hepatic concentrations of low molecular polycyclic aromatic hydrocarbons and polychlorinated biphenyls when compared to fish from Welaka. Metals were more variable across sites, with highest mean concentrations found in bass from either Julington Creek (Ag, As, Cr, Cu, Zn) or Welaka (Cd, Hg, Pb, Se, Tn). Female bass from Palatka and Green Cove had lower concentrations of E2, VTG and lower GSI in relation to Welaka. Males from Palatka and Green Cove showed comparable declines in 11-KT in relation to males from Julington Creek and GSI were decreased only in Palatka males. These results indicate a geographical trend in reproductive effects, with changes being most pronounced at the site closest to the paper mill (Palatka) and decreasing as the St. Johns River flows downstream. Since reproductive alterations were most evident in bass sampled from the site closest to the paper mill discharge, it is possible that exposure to these effluents might explain at least some of the results reported here. However, the presence of reproductive alterations in fish sampled at a considerable distance from the mill discharge (Green Cove, 40 km) would suggest exposure to chemicals released from sources other than the paper mill plant. It is clear that additional studies are needed to evaluate the potential impact of these reproductive changes in populations of Florida largemouth bass inhabiting the St. Johns River. ?? 2002 Elsevier Science B.V. All rights reserved.

ST09, a Novel Thioester Derivative of Tacrine, Alleviates Cognitive Deficits and Enhances Glucose Metabolism in Vascular Dementia Rats.

PubMed

Liu, Jian-Min; Wu, Peng-Fei; Rao, Jing; Zhou, Jun; Shen, Zu-Cheng; Luo, Han; Huang, Jian-Geng; Liang, Xiao; Long, Li-Hong; Xie, Qing-Guo; Jiang, Feng-Chao; Wang, Fang; Chen, Jian-Guo

2016-03-01

Chemical entities containing mercapto group have been increasingly attractive in the therapy of central nerve system (CNS) diseases. In the recent study, we screened a series of mercapto-tacrine derivatives with synergistic neuropharmacological profiles in vitro. We investigated the effect and mechanism of ST09, a thioester derivative of tacrine containing a potential mercapto group, on the vascular dementia (VaD) model of rat induced by bilateral common carotid arteries occlusion (2-VO). ST09 and its active metabolite ST10 retained excellent inhibition on acetylcholinesterase (AChE) activity. ST09 significantly attenuated the 2-VO-induced impairment in spatial acquisition performance and inhibited the 2-VO-induced rise of AChE activity. In the VaD model, ST09 attenuated the oxidative stress and decreased the apoptosis in the cortex and hippocampus. Compared with donepezil, ST09 exhibited a better effect on the regeneration of free thiols in 2-VO rats. Interestingly, ST09, not donepezil, greatly improved glucose metabolism in various brain regions of 2-VO rats using functional imaging of (18) F-labeled fluoro-deoxyglucose (FDG) positron emission tomography (PET). ST09 may serve as a more promising agent for the therapy of VaD than tacrine owing to the introduction of a potential mercapto group into the parent skeleton. © 2016 John Wiley & Sons Ltd.

Mouse Hepatitis Virus Infection Suppresses Modulation of Mouse Spleen T- Cell Activation

DTIC Science & Technology

1988-01-01

supplemented with 50 gM 2-mercaptoethanol (Sigma, St. Louis, MO), 100 U/ml penicillin and 100 gg/ml streptomycin (Sigma). Mice were sacrificed by...husbandry and clinical studies. The authors also thank Drs. Abigail Smith, Margalit Mokyr, Robert Hendricks , Katherine Knight, Rhonna Cohen, and John

Integrated marketing.

PubMed

2006-01-01

St. John Health consists of nine hospitals throughout southern Michigan. Recently, in an attempt to brand the system as the state's premiere place for medical services, the system launched 'Real Medicine', a campaign that brands all nine hospitals together. Using print, radio, and television spots, the effort also integrates direct mail collateral and brochures to reach consumers.

Recognizing resilience

Treesearch

Erika S. Svendsen; Gillian Baine; Mary E. Northridge; Lindsay K. Campbell; Sara S. Metcalf

2014-01-01

In 2012, a year after a devastating tornado hit the town of Joplin, Missouri, leaving 161 people dead and leveling Joplin High School and St. John's Hospital, President Obama addressed the graduating seniors: "There are a lot of stories here in Joplin of unthinkable courage and resilience. . . . [People in Joplin] learned that we have the power to...

Modeling spatio-temporal wildfire ignition point patterns

Treesearch

Amanda S. Hering; Cynthia L. Bell; Marc G. Genton

2009-01-01

We analyze and model the structure of spatio-temporal wildfire ignitions in the St. Johns River Water Management District in northeastern Florida. Previous studies, based on the K-function and an assumption of homogeneity, have shown that wildfire events occur in clusters. We revisit this analysis based on an inhomogeneous K-...

Use of Nonvitamin, Nonmineral Dietary Supplements among College Students.

ERIC Educational Resources Information Center

Newberry, Heather; Beerman, Kathy; Duncan, Sam; McGuire, Michelle; Hillers, Virginia

2001-01-01

Assessed college students' use of nonvitamin, nonmineral (NVNM) dietary supplements. Student surveys indicated that nearly half of the respondents took NVNM supplements, most frequently echinacea, ginseng, and St. John's wort. Over 80 percent had acceptable body mass index values. Users and nonusers of NVNM supplements did not differ significantly…

Self-Knowledge and Character Formation: Teaching to Students' Weaknesses

ERIC Educational Resources Information Center

Griffis, Rachel B.

2017-01-01

This article considers David Brooks' recent "New York Times" bestseller, The "Road to Character", in light of Christian thinkers on the connection between virtue and suffering, specifically Dante and St John of the Cross. By putting Brooks in conversation with the Christian tradition, I show how his ideas, specifically his…

A New Script for Working with Parents

ERIC Educational Resources Information Center

Wischnowski, Michael W.; Cianca, Marie

2012-01-01

Parent/teacher relationships are fraught with potential for perilous misunderstandings amid what often are construed as conflicting interests. Perhaps that is nowhere more true than in parent/teacher relationships regarding children with disabilities. The authors report on a program at St. John Fisher College where teams of preservice teachers…

Law School Financial Planning and Debt Management Brochure.

ERIC Educational Resources Information Center

Belmont, Jean

Information on managing debt acquired by St. John's University law students is provided. The cost of education for a graduate student includes tuition, fees, books, home maintenance, personal expenses, and transportation. A student budget for 1984-1985 is provided by students' dependency status (dependent 9 months, 9-month residency/dependent, and…

Larch Dwarf Mistletoe (FIDL)

Treesearch

Jerome S. Beatty; Gregory M. Filip; Robert L. Mathiason

1997-01-01

Larch dwarf mistletoe (Arceuthobium laricis (Piper) St. John) is a common and damaging parasite of western larch (Larix occidentalis Nutt.) in the Pacific Northwest and southern British Columbia. Larch dwarf mistletoe occurs commonly throughout the range of western larch in British Columbia, northern and central Idaho, western Montana and east of the Cascades in...

The Use of Mobile Technology for Work-Based Assessment: The Student Experience

ERIC Educational Resources Information Center

Coulby, Ceridwen; Hennessey, Scott; Davies, Nancy; Fuller, Richard

2011-01-01

This paper outlines a research project conducted at Leeds University School of Medicine with Assessment & Learning in Practice Settings Centre for Excellence in Teaching and Learning, collaboration between the Universities of Leeds, Huddersfield, Bradford, Leeds Metropolitan University and the University of York St John. The research conducted…

Culturally and economically important nontimber forest products of northern Maine

Treesearch

Michelle J. Baumflek; Marla R. Emery; Clare Ginger

2010-01-01

Nontimber forest products (NTFPs) gathered for food, medicine, craft, spiritual, aesthetic, and utilitarian purposes make substantial contributions to the economic viability and cultural vitality of communities. In the St. John River watershed of northern Maine, people identifying with cultural groups including Acadian, Maliseet, Mi'kmaq, Scotch-Irish, and Swedish...

The Ayre's T-piece turns 80: A 21st century review.

PubMed

Oswald, Lauren; Smith, Emma-Jane; Mathew, Malcolm; Goonasekera, Chulananda

2018-06-07

Ayre's T-piece, first introduced 80 years ago, continues to be widely used in pediatric anesthesia despite colossal advances in equipment and technology. We present a review of its history, advantages, and disadvantages, and place in modern-day clinical practice. © 2018 John Wiley & Sons Ltd.

The Greening of a University: The St. John's Sustainability Initiative

ERIC Educational Resources Information Center

Pellow, James P.; Anand, Brij

2009-01-01

With "greening" projects dotting the landscape of higher education across the nation, it is encouraging to witness the commitment of many colleges and universities to helping secure the future environmental viability of the nation. The challenges that come with this commitment, however, are not insignificant. A comprehensive…

77 FR 67341 - Endangered Species; File No. 15809

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-09

... Species; File No. 15809 AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... Paul Jobsis, Ph.D., University of the Virgin Islands, Department of Biology, 2 John Brewers Bay, St... of Protected Resources, National Marine Fisheries Service. [FR Doc. 2012-27343 Filed 11-8-12; 8:45 am...

29 CFR 1610.4 - Public reference facilities and current index.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (New York District), 1 Newark Center, 21st Floor, Newark, NJ 07102-5233. New Orleans Field Office (Houston District), 1555 Poydras, Suite 1900, New Orleans, LA 70112. New York District Office, 33 Whitehall..., Birmingham, AL 35205-2397. Boston Area Office (New York District), John F. Kennedy Federal Building...

Meteorological influences on algal bloom potential in a nutrient-rich blackwater river

EPA Science Inventory

The effect of variability in rainfall on the potential for algal blooms was examined for the St. Johns River in northeast Florida. Water chemistry and phytoplankton data were collected at selected sites monthly from 1993 through 2003. Information on rainfall and estimates ofw at...

Academic Achievement of Children in China: The 2002 Fulbright Experience

ERIC Educational Resources Information Center

Phelps, LeAdelle

2005-01-01

The 2002 Fulbright team, led by Zheng Zhou of St. John's University, consisted of 12 professionals in the fields of education, counseling psychology, and school psychology. Spending one month visiting elementary schools, universities, governmental bodies, hospitals, and private schools throughout China, the Fulbright team had an opportunity to…

Alboleptonia from the Greater Antilles

Treesearch

T. J. Baroni; D. J. Lodge

1998-01-01

Four new species of Alboleptonia are described from Puerto Rico and new distribution records for Alboleptonia are noted for Puerto Rico and St. John, U.S. Virgin Islands. Information from examination of the type collections of Alboleptonia aripoana, A. cyathiformis, and A. hyalodepas is discussed. Clarification of conflicting reports in the literature concerning the...

NCCAM's 5 Most Searched-For Herbs of 2012: What the Science Says about Evening Primrose Oil, St. John's Wort, Fenugreek,...

MedlinePlus

... Resources CME/CEU and Online Lectures Online Continuing Education Series Distinguished Lecture Series Integrated Medicine Research Lecture ... has been a source of many folk or traditional remedies and more modern medicinal and cosmetic products. At various times aloe ...

Atlantic salmon breeding program at the National Cold Water Marine Aquaculture Center

USDA-ARS?s Scientific Manuscript database

The USDA-ARS National Cold Water Marine Aquaculture Center (NCWMAC) in Franklin, ME has been supporting the U.S. coldwater marine aquaculture industry for the past thirteen years by developing a genetically improved North American Atlantic salmon. The St. John's River stock was chosen as the focal ...

Environmental setting and factors that affect water quality in the Georgia-Florida Coastal Plain study unit

USGS Publications Warehouse

Berndt, M.P.; Oaksford, E.T.; Darst, M.R.; Marella, R.L.

1996-01-01

The Georgia-Florida Coastal Plain study unit covers an area of nearly 62,000 square miles in the southeastern United States, mostly in the Coastal Plain physiographic province. Land resource provinces have been designated based on generalized soil classifications. Land resource provinces in the study area include: the Coastal Flatwoods, the Southern Coastal Plain, the Central Florida Ridge, the Sand Hills, and the Southern Piedmont. The study area includes all or parts of seven hydrologic subregions: the Ogeechee-Savannah, the Altamaha- St.Marys, the Suwannee, the Ochlockonee, the St. Johns, the Peace-Tampa Bay, and the Southern Florida. The primary source of water for public supply in the study area is ground water from the Upper Floridan aquifer. In 1990, more than 90 percent of the 2,888 million gallons per day of ground water used came from this aquifer. The population of the study area was 9.3 million in 1990. The cities of Jacksonville, Orlando, St. Petersburg, Tallahassee, and Tampa, Florida, and parts of Atlanta and Savannah, Georgia, are located in the study area. Forest and agricultural areas are the most common land uses in the study area, accounting for 48 percent and 25 percent of the study area, respectively. Climatic conditions range from temperate in Atlanta, Georgia, where mean annual temperature is about 61.3 degrees Fahrenheit, to subtropical in Tampa, Florida, where mean annual temperature is about 72.4 degrees Fahrenheit. Long-term average precipitation (1961-90) ranges from 43.9 inches per year in Tampa, Florida, and 44.6 in Macon, Georgia, to 65.7 inches per year in Tallahassee, Florida. Floods in the study area result from frontal systems, hurricanes, tropical storms, or severe thunderstorms. Droughts are not common in the study area,especially in the Florida part of the study area due to extensive maritime exposure. The primary physical and cultural characteristics in the study area include physiography, soils and land resource provinces, geologic setting, ground-water systems, surface- water systems, climate, floods, droughts, population, land use, and water use. Factors affecting water quality in the study area are land use (primarily urban and agricultural land uses), water use in coastal areas, hydrogeology, ground-water/surface-water interaction, geology, and climate. Surface-water quality problems in urban areas have occurred in the Ogeechee, Canoochee, Ocmulgee, St. Marys, Alapaha, Withlacoochee (north), Santa Fe, Ochlockonee, St. Johns, and Oklawaha Rivers and include nitrogen and phosphorus loading, low dissolved oxygen, elevated bacteria, sediment, and turbidity, and increased concentrations of metals. In agricultural areas, surface-water quality problems include elevated nitrogen and phosphorus concentrations, erosion, and sedimentation and have occurred in the Ocmulgee, St. Marys, Santa Fe, Ochlockonee, St. Johns, Oklawaha, Withlacoochee (South), Hillsborough, and Alafia Rivers. Ground water-quality problems such as saltwater intrusion have occurred mostly in coastal areas and were caused by excessive withdrawals.

Comparative analysis of the virulence characteristics of epidemic methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from Chinese children: ST59 MRSA highly expresses core gene-encoded toxin.

PubMed

Li, Shipeng; Sun, Jing; Zhang, Jianzhong; Li, Xiangmei; Tao, Xiaoxia; Wang, Lijuan; Sun, Mingjiao; Liu, Yingchao; Li, Juan; Qiao, Yanhong; Yu, Sangjie; Yao, Kaihu; Yang, Yonghong; Shen, Xuzhuang

2014-02-01

This study aims to investigate the prevalence of a novel cell wall-anchored protein gene, sasX, and to obtain information on the genetic basis for the pathogenic potential of the MRSA strains isolated from Chinese children. The molecular and virulence characteristics of the clinical strains were analyzed. Twenty-two sequence types (STs) were obtained, with six epidemic clones ST59, ST239, ST1, ST910, ST88, and ST338 accounting for 35.8, 22, 6.6, 6.6, 5.3, and 4.1% respectively. The expression levels of hla, psmα, and RNAIII were higher in ST59 than in other STs (p < 0.05). The sasX gene was detected in 26 (10.7%) MRSA isolates. ST239-MRSA-SCCmecIII-t037 (61.5%) was the predominant sasX-positive MRSA clone. The expressions of PSMα and RNAIII were higher in sasX-positive ST239 isolates than in sasX-negative ST239 ones (p < 0.01). Notably, the percentage of invasive infection in infections caused by sasX-positive ST239 MRSA was higher than that by sasX-negative ST239 MRSA (p = 0.008). This study indicated that ST59 was the predominant clone in the MRSA isolates obtained from Chinese children and might have stronger pathogenic potential. The prevalence of the sasX gene in the MRSA isolates from children was relatively low. Furthermore, the sasX gene might be related to the expressions of PSMα and RNAIII and infection invasiveness. © 2013 APMIS Published by John Wiley & Sons Ltd.

Integrating Renewable Energy into the Transmission and Distribution System of the U. S. Virgin Islands

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burman, K.; Olis, D.; Gevorgian, V.

2011-09-01

This report focuses on the economic and technical feasibility of integrating renewable energy technologies into the U.S. Virgin Islands transmission and distribution systems. The report includes three main areas of analysis: 1) the economics of deploying utility-scale renewable energy technologies on St. Thomas/St. John and St. Croix; 2) potential sites for installing roof- and ground-mount PV systems and wind turbines and the impact renewable generation will have on the electrical subtransmission and distribution infrastructure, and 3) the feasibility of a 100- to 200-megawatt power interconnection of the Puerto Rico Electric Power Authority (PREPA), Virgin Islands Water and Power Authority (WAPA),more » and British Virgin Islands (BVI) grids via a submarine cable system.« less

Effect of temperature and seven storage media on human periodontal ligament fibroblast viability.

PubMed

de Souza, Beatriz Dulcineia Mendes; Bortoluzzi, Eduardo Antunes; Reyes-Carmona, Jessie; Dos Santos, Luciane Geanini Pena; Simões, Claudia Maria de Oliveira; Felippe, Wilson Tadeu; Felippe, Mara Cristina Santos

2017-04-01

Natural resources, such as coconut water, propolis, and egg whites, have been examined as possible storage media for avulsed teeth. However, there is a lack of research focused on the efficacy of these three products together compared with Hank's balanced salt solution and milk. The aim of this study was to evaluate the capacity of seven storage media to maintain the viability of human periodontal ligament fibroblasts (PDLFs). PDLFs were kept at 5°C and 20°C, in skimmed milk (SMilk), whole milk (WMilk), recently prepared Hank's balanced salt solution (HBSS), Save-A-Tooth ® system's HBSS (Save), natural coconut water (Coconut), Propolis, and egg white (Egg) for 3, 6, 24, 48, 72, 96, and 120 h, through the analysis of tetrazolium salt-based colorimetric (MTT) assay. At 5°C, SMilk and WMilk were better than HBSS in maintaining cell viability, from 24 h onward. At 20°C, HBSS was the best storage medium at 96 and 120 h. At both temperatures, from 6 h onward, Coconut, Propolis and Egg were less effective than SMilk, WMilk, and HBSS. In general, the performance of Coconut, Propolis and Egg were not influenced by storage temperature. However, the lowest temperature undermined the effectiveness of HBSS from 24 h and favored SMilk and WMilk, from 96 and 48 h onward, respectively. Save and water were the worst storage media. SMilk was the best storage medium, followed by WMilk and HBSS. Coconut, Propolis, and Egg can be indicated for the conservation of PDLF up to 3 h. The lower temperature (5°C) undermined the effectiveness of HBSS and favored SMilk and WMilk. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Efficiency of different storage media for avulsed teeth in animal models: a systematic review.

PubMed

Longo, Daniele L; Fumes, Ana C; Küchler, Erika C; Paula-Silva, Francisco W G; Nelson-Filho, Paulo; Silva, Léa A B

2018-02-01

Tooth avulsion consists of the complete displacement of a tooth from the alveolar socket. When immediate replantation is not possible, the avulsed tooth should be kept in a storage medium capable of maintaining the viability of periodontal ligament (PDL) cells on the root surface. However, there is no consensus on the best storage medium able to prevent sequels such as ankylosis and tooth resorption. The aim of this study was to perform a systematic review to evaluate the in vivo effectiveness of different storage media for avulsed teeth. Two reviewers performed a database search for studies published between January 1950 and December 2015 which were indexed in the PubMed, Scopus, Web of Science, and Bireme databases. An additional manual search was performed. Studies with animal models that evaluated tooth avulsion, storage media, and replantation were included. After full-text analysis of the potentially relevant studies, the selected studies were included in the systematic review. The database search found 157 distinct studies evaluating avulsed teeth storage media. However, only six studies met the selection criteria and were included in the review. There was a high variability in the study estimates for the parameters analyzed. When assessing the quality and level of evidence of each study, one study was rated as having a very low level of evidence, four studies had low levels of evidence, and one had a moderate level of evidence. As a result of data heterogeneity and limitations of the studies, there was insufficient evidence to determine the most effective storage medium for avulsed teeth. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Discussion on wound care in the 21st century.

PubMed

Harrison, Mary

In June of this year, Liverpool John Moores University was the venue for the Advancing Wound Care conference. Experts in wound healing from both the university and from the Royal Liverpool and Broadgreen University Hospital NHS Trust gave keynote speeches aimed at informing, improving and advancing healthcare knowledge on such topics as: wound healing in the 21st century; evidence-based practice for superficial burns; infected and complex wounds; and the use of silver in wound care. This paper introduced the conference and considered some of the complex issues involved in clinical decision making for wound management.

New geographic records of Hamlets, Hypoplectrus spp. (Serranidae), in the Caribbean Sea

USGS Publications Warehouse

Williams, Ernest H.; Bunkley-Williams, Lucy; Rogers, Caroline S.; Fenner, Robert

2006-01-01

The exact number of species of hamlets, Hypoplectrus spp., in the Caribbean is controversial and the geographic distributions of these species/forms are poorly documented. We report Curaçao, Netherlands Antilles, as a new locality for the Barred Hamlet, H. puella (Cuvier), and Shy Hamlet, H. guttavarius (Poey); and St. John and St. Thomas, U.S. Virgin Islands, for the Tan Hamlet, Hypoplectrus sp. The Black Hamlet, H. nigricans (Poey), has previously been reported from Curaçao, but we did not see it there.

What Happens If They Say No? Preserving Access to Critical Commercial Space Capabilities during Future Crises

DTIC Science & Technology

2014-12-01

SatelliteShortagesMayChokeOffMilitaryDroneExpansion.aspx; G. Ryan Faith and Mariel John , “Space Report 2011” in Authoritative Guide to Global Space Activity,” ed. Micah Walter-Range (Colorado Springs...Werner, “Cover Story”; John Walcott, “Chinese Espionage Campaign Targets U.S. Space Technology,” Bloomberg, 18 April 2012, http://www.bloomberg.com...frus1969-76v25.pdf; Walter J. Boyne , The Two O’Clock War: The 1973 Yom Kippur Conflict and the Airlift That Saved Israel, 1st ed. (New York: Thomas

Muscle activation patterns in the Nordic hamstring exercise: Impact of prior strain injury.

PubMed

Bourne, M N; Opar, D A; Williams, M D; Al Najjar, A; Shield, A J

2016-06-01

This study aimed to determine: (a) the spatial patterns of hamstring activation during the Nordic hamstring exercise (NHE); (b) whether previously injured hamstrings display activation deficits during the NHE; and (c) whether previously injured hamstrings exhibit altered cross-sectional area (CSA). Ten healthy, recreationally active men with a history of unilateral hamstring strain injury underwent functional magnetic resonance imaging of their thighs before and after six sets of 10 repetitions of the NHE. Transverse (T2) relaxation times of all hamstring muscles [biceps femoris long head (BFlh); biceps femoris short head (BFsh); semitendinosus (ST); semimembranosus (SM)] were measured at rest and immediately after the NHE and CSA was measured at rest. For the uninjured limb, the ST's percentage increase in T2 with exercise was 16.8%, 15.8%, and 20.2% greater than the increases exhibited by the BFlh, BFsh, and SM, respectively (P < 0.002 for all). Previously injured hamstring muscles (n = 10) displayed significantly smaller increases in T2 post-exercise than the homonymous muscles in the uninjured contralateral limb (mean difference -7.2%, P = 0.001). No muscles displayed significant between-limb differences in CSA. During the NHE, the ST is preferentially activated and previously injured hamstring muscles display chronic activation deficits compared with uninjured contralateral muscles. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Comparative Analysis of Glaciers in the Chugach-St.-Elias Mountains

NASA Astrophysics Data System (ADS)

Herzfeld, U. C.; Mayer, H.

2003-12-01

The phenomenon of glacier surges has to date been studied for only relatively few examples. 136 of the 204 surge-type glaciers in North America listed by Post (1969) are located in the St. Elias Mountains. In August 2003 we increased our data inventory of observations on surge glaciers by collecting material for 19 glaciers in the Glacier Bay area and neighboring regions in the eastern St. Elias Mountains, including 6 surge-type glaciers (Carroll, Rendu, Ferris, Grand Pacific, Margerie, and Johns Hopkins Glaciers). Analyses utilize digital video and photographic data, satellite data and GPS data. Geostatistical classification parameters and algebraic parameters characteristic of surge motions are derived for selected glaciers. During the 1993-1995 surge of Bering Glacier the entire surface of Alaska's longest glacier was crevassed and could be segmented into several dynamic provinces, where patterns changed as the surge progressed and the affected areas expanded downglacier and upglacier, finally affecting the Bagley Ice Field. The middle moraine of Grand Pacific and Ferris Glaciers is pushed over to the Grand Pacific side, caused by a recent surge of the heavily crevassed Ferris Glacier. The front of Johns Hopkins Glacier advances, as its lower reaches are affected by a surge. The surge history of Bering Glacier goes back to the Holocene, whereas Carroll and Rendu Glaciers have surged only 3-4 times. These observations pose questions on the possible relationship between surge dynamics and climatic changes.

Genomic comparison of virulent and non-virulent Streptococcus agalactiae in fish.

PubMed

Delannoy, C M J; Zadoks, R N; Crumlish, M; Rodgers, D; Lainson, F A; Ferguson, H W; Turnbull, J; Fontaine, M C

2016-01-01

Streptococcus agalactiae infections in fish are predominantly caused by beta-haemolytic strains of clonal complex (CC) 7, notably its namesake sequence type (ST) 7, or by non-haemolytic strains of CC552, including the globally distributed ST260. In contrast, CC23, including its namesake ST23, has been associated with a wide homeothermic and poikilothermic host range, but never with fish. The aim of this study was to determine whether ST23 is virulent in fish and to identify genomic markers of fish adaptation of S. agalactiae. Intraperitoneal challenge of Nile tilapia, Oreochromis niloticus (Linnaeus), showed that ST260 is lethal at doses down to 10(2) cfu per fish, whereas ST23 does not cause disease at 10(7) cfu per fish. Comparison of the genome sequence of ST260 and ST23 with those of strains derived from fish, cattle and humans revealed the presence of genomic elements that are unique to subpopulations of S. agalactiae that have the ability to infect fish (CC7 and CC552). These loci occurred in clusters exhibiting typical signatures of mobile genetic elements. PCR-based screening of a collection of isolates from multiple host species confirmed the association of selected genes with fish-derived strains. Several fish-associated genes encode proteins that potentially provide fitness in the aquatic environment. © 2014 John Wiley & Sons Ltd.

Report on UQ and PCMM Analysis of Vacuum Drying for UFD S&T Gaps

DOE Office of Scientific and Technical Information (OSTI.GOV)

M. Fluss

2015-08-31

This report discusses two phenomena that could affect the safety, licensing, transportation, storage, and disposition of the spent fuel storage casks and their contents (radial hydriding during drying and water retention after drying) associated with the drying of canisters for dry spent fuel storage. The report discusses modeling frameworks and evaluations that are, or have been, developed as a means to better understand these phenomena. Where applicable, the report also discusses data needs and procedures for monitoring or evaluating the condition of storage containers during and after drying. A recommendation for the manufacturing of a fully passivated fuel rod, resistantmore » to oxidation and hydriding is outlined.« less

Longitudinal social cognitive influences on physical activity and sedentary time in Hispanic breast cancer survivors.

PubMed

Mama, Scherezade K; Song, Jaejoon; Ortiz, Alexis; Tirado-Gomez, Maribel; Palacios, Cristina; Hughes, Daniel C; Basen-Engquist, Karen

2017-02-01

This study evaluated the effect of two home-based exercise interventions (one culturally adapted and one standard) on changes in social cognitive theory (SCT) variables, physical activity (PA), and sedentary time (ST), and determined the association between changes in SCT variables and changes in PA and ST in Hispanic breast cancer survivors. Project VIVA! was a 16-week randomized controlled pilot study to test the effectiveness and feasibility of a culturally adapted exercise intervention for Mexican American and Puerto Rican breast cancer survivors in Houston, Texas and San Juan, Puerto Rico, respectively. Women (N = 89) completed questionnaires on SCT variables, PA, and ST and were then randomized to a 16-week culturally adapted exercise program, a non-culturally adapted standard exercise intervention or a wait-list control group. Multiple regression models were used to determine associations between changes in SCT variables and changes in PA and ST. Participants were in their late 50s (58.5 ± 9.2 years) and obese (31.0 ± 6.5 kg/m 2 ). Women reported doing roughly 34.5 min/day of PA and spending over 11 h/day in sedentary activities. Across groups, women reported significant increases in exercise self-efficacy and moderate-intensity, vigorous-intensity, and total PA from baseline to follow-up (p < 0.05). Increased social support from family was associated with increases in vigorous-intensity PA. Increases in social modeling were associated with increases in moderate-intensity and total PA and with decreases in ST from baseline to follow-up (p < 0.05). Hispanic cancer survivors benefit from PA interventions that focus on increasing social support from family and friends and social modeling. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

The direction of cloud computing for Malaysian education sector in 21st century

NASA Astrophysics Data System (ADS)

Jaafar, Jazurainifariza; Rahman, M. Nordin A.; Kadir, M. Fadzil A.; Shamsudin, Syadiah Nor; Saany, Syarilla Iryani A.

2017-08-01

In 21st century, technology has turned learning environment into a new way of education to make learning systems more effective and systematic. Nowadays, education institutions are faced many challenges to ensure the teaching and learning process is running smoothly and manageable. Some of challenges in the current education management are lack of integrated systems, high cost of maintenance, difficulty of configuration and deployment as well as complexity of storage provision. Digital learning is an instructional practice that use technology to make learning experience more effective, provides education process more systematic and attractive. Digital learning can be considered as one of the prominent application that implemented under cloud computing environment. Cloud computing is a type of network resources that provides on-demands services where the users can access applications inside it at any location and no time border. It also promises for minimizing the cost of maintenance and provides a flexible of data storage capacity. The aim of this article is to review the definition and types of cloud computing for improving digital learning management as required in the 21st century education. The analysis of digital learning context focused on primary school in Malaysia. Types of cloud applications and services in education sector are also discussed in the article. Finally, gap analysis and direction of cloud computing in education sector for facing the 21st century challenges are suggested.

Solanum tuberosum ZPR1 encodes a light-regulated nuclear DNA-binding protein adjusting the circadian expression of StBBX24 to light cycle.

PubMed

Kiełbowicz-Matuk, Agnieszka; Czarnecka, Jagoda; Banachowicz, Ewa; Rey, Pascal; Rorat, Tadeusz

2017-03-01

ZPR1 proteins belong to the C4-type of zinc finger coordinators known in animal cells to interact with other proteins and participate in cell growth and proliferation. In contrast, the current knowledge regarding plant ZPR1 proteins is very scarce. Here, we identify a novel potato nuclear factor belonging to this family and named StZPR1. StZPR1 is specifically expressed in photosynthetic organs during the light period, and the ZPR1 protein is located in the nuclear chromatin fraction. From modelling and experimental analyses, we reveal the StZPR1 ability to bind the circadian DNA cis motif 'CAACAGCATC', named CIRC and present in the promoter of the clock-controlled double B-box StBBX24 gene, the expression of which peaks in the middle of the day. We found that transgenic lines silenced for StZPR1 expression still display a 24 h period for the oscillation of StBBX24 expression but delayed by 4 h towards the night. Importantly, other BBX genes exhibit altered circadian regulation in these lines. Our data demonstrate that StZPR1 allows fitting of the StBBX24 circadian rhythm to the light period and provide evidence that ZPR1 is a novel clock-associated protein in plants necessary for the accurate rhythmic expression of specific circadian-regulated genes. © 2016 John Wiley & Sons Ltd.

Effects of Two Application Methods of Plantaricin BM-1 on Control of Listeria monocytogenes and Background Spoilage Bacteria in Sliced Vacuum-Packaged Cooked Ham Stored at 4°C.

PubMed

Zhou, Huimin; Xie, Yuanhong; Liu, Hui; Jin, Junhua; Duan, Huixia; Zhang, Hongxing

2015-10-01

Two application methods were used to investigate the effect of plantaricin BM-1 on the control of Listeria monocytogenes and background spoilage bacteria in sliced vacuum-packaged cooked ham without the addition of any chemical preservatives, including sodium nitrite, during 35 days of storage at 4°C. Regardless of the application method, plantaricin BM-1 treatment (320, 640, or 1,280 arbitrary units [AU]/g of sliced cooked ham) significantly (P < 0.05) reduced the survival of L. monocytogenes (inoculated at 4 log CFU/g of sliced ham) compared with its survival in the control during the first 21 days of storage at 4°C. The inhibitory effect of plantaricin applied to the surface of the ham was significantly better than the same concentration of plantaricin incorporated into the cooked ham (P < 0.0001) during storage. Even 320 AU/g plantaricin applied to the surface exhibited greater inhibition of L. monocytogenes than 1,280 AU/g plantaricin incorporated into the cooked ham on days 1, 14, and 28. A level of 1,280 AU/g plantaricin applied to the surface of the ham reduced L. monocytogenes counts to below the detection limit from the 1st to the 21st day of storage at 4°C. Afterwards, L. monocytogenes was able to regrow, and the viable counts of L. monocytogenes at the end of storage reached 2.76 log CFU/g (6.11 log CFU/g lower than in the control). In the control ham, the counts of background spoilage bacteria increased gradually and surpassed the microbiological spoilage limitation level on the 21st day of storage. However, plantaricin BM-1 treatment significantly (P < 0.05) reduced the survival of background spoilage bacteria in ham compared with their survival in the control from day 21 to 35 of storage at 4°C. A level of 1,280 AU/g plantaricin incorporated into cooked ham was the most effective, reducing the count of background spoilage bacteria count from an initial 2.0 log CFU/g to 1.5 log CFU/g on day 7. This was then maintained for another 14 days and finally increased to 2.76 log CFU/g at the end of the storage at 4°C (2.85 log CFU/g lower than in the control). In conclusion, plantaricin BM-1 application inhibited the growth of L. monocytogenes and background spoilage bacteria in cooked ham during storage at 4°C and could be used as an antimicrobial additive for meat preservation.

Long-term stability of peri-implant tissues after bone or soft tissue augmentation. Effect of zirconia or titanium abutments on peri-implant soft tissues. Summary and consensus statements. The 4th EAO Consensus Conference 2015.

PubMed

Sicilia, Alberto; Quirynen, Marc; Fontolliet, Alain; Francisco, Helena; Friedman, Anton; Linkevicius, Tomas; Lutz, Rainer; Meijer, Henny J; Rompen, Eric; Rotundo, Roberto; Schwarz, Frank; Simion, Massimo; Teughels, Wim; Wennerberg, Ann; Zuhr, Otto

2015-09-01

Several surgical techniques and prosthetic devices have been developed in the last decades, aiming to improve aesthetic, hygienic and functional outcomes that may affect the peri-implant tissues, such as procedures of bone and soft tissue augmentation and the use of custom-made abutments of titanium and zirconium. Three systematic reviews, based on randomized clinical trials and prospective studies covering the above reported topics were analysed, and the detected evidence was exposed to interactive experts' discussion during the group's and general assembly's meetings of the 4th EAO Consensus Conference. The results are reported using the following abbreviations: S-T: short-term evidence, M-T: medium-term evidence; L-T: long-term evidence; LE: limited evidence. Soft tissue augmentation procedures may be indicated for the increase of soft tissue thickness and keratinized tissue, the reduction of interproximal peri-implant bone loss, and the coverage of shallow peri-implant soft tissue recessions (S-T, LE), L-T is lacking. Guided bone regeneration approaches (GBR) showed efficacy when used for ridge reconstruction after the complete healing of the soft tissues (S-T & L-T), and the stability of the augmented bone may play a role in the maintenance of the soft tissue position and dimensions (LE). No significant differences were observed between titanium and zirconia abutments when evaluating probing pocket depth, bleeding on probing, marginal bone levels and mucosal recessions. Zirconia abutments were associated with more biological complications but demonstrated superiority in terms of achieving natural soft tissue colour (S-T). © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

James Gregory, the University observatory and the early acquisition of scientific instruments at the University of St Andrews

PubMed Central

Rawson, Helen C.

2015-01-01

James Gregory, inventor of the reflecting telescope and Fellow of the Royal Society, was the first Regius Professor of Mathematics of the University of St Andrews, 1668–74. He attempted to establish in St Andrews what would, if completed, have been the first purpose-built observatory in the British Isles. He travelled to London in 1673 to purchase instruments for equipping the observatory and improving the teaching and study of natural philosophy and mathematics in the university, seeking the advice of John Flamsteed, later the first Astronomer Royal. This paper considers the observatory initiative and the early acquisition of instruments at the University of St Andrews, with reference to Gregory's correspondence, inventories made ca. 1699–ca. 1718 and extant instruments themselves, some of which predate Gregory's time. It examines the structure and fate of the university observatory, the legacy of Gregory's teaching and endeavours, and the meridian line laid down in 1748 in the University Library.

STS-121: Discovery Mission Management Team Briefing

NASA Technical Reports Server (NTRS)

2006-01-01

The briefing opened with Bruce Buckingham (NASA Public Affairs) introducing John Shannon (Chairman, Mission Management Team, JSC), John Chapman (External Tank Project Manager), Mike Leinbach (Shuttle Launch Director), and 1st Lt. Kaleb Nordgren (USAF 45th Weather Squadron). John Shannon reported that the team for hydrogen loading was proceeding well and the external tank detanking was completed. During detanking the inspection team cracked foam caused by condensation and ice formation as the tank expanded and contracted. Aerothermal analysis and analysis fro ice formation will be completed before launch. John Chapman explained the mechanics of the external tank design, the foam cracking, bracket design, etc. Mike Leinbach discussed the inspection teams and their inspection final inspection for ice formation before and after external tank filling. The inspection team of eight very experienced personnel also use telescopes with cameras to find any problems before launch. Kaleb Nordgren discussed weather and said there was a 40% chance of weather prohibiting launch. The floor was the opened for questions from the press.

33 CFR 117.325 - St. Johns River.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., displaying flashing green lights to indicate that vessels may pass. (3) When a train approaches, large signs on both the upstream and downstream sides of the bridge flash “Bridge Coming Down,” the lights go to... track circuit is occupied. (4) After the train has cleared, the draw opens and the lights return to...

Using Commercial-Off-The-Shelf Speech Recognition Software for Conning U.S. Warships

DTIC Science & Technology

2003-06-01

Linear Regression , 2nd Edition, (John Wiley & Sons, St. Paul, Minnesota, 1985), pp. 267-269. 44 Current Projects About the Sigmoid Curve, Sigmoid Curve...Disabilities Conference, Conference Proceedings, [www.csun.edu/cod/conf/1998/proceedings/csun98_052.htm], as of June 2, 2003. 43 Weisberg, S., Applied

Teaching Analytical Method Transfer through Developing and Validating Then Transferring Dissolution Testing Methods for Pharmaceuticals

ERIC Educational Resources Information Center

Kimaru, Irene; Koether, Marina; Chichester, Kimberly; Eaton, Lafayette

2017-01-01

Analytical method transfer (AMT) and dissolution testing are important topics required in industry that should be taught in analytical chemistry courses. Undergraduate students in senior level analytical chemistry laboratory courses at Kennesaw State University (KSU) and St. John Fisher College (SJFC) participated in development, validation, and…

Practitioners' & LIS Students' Perceptions on Preparedness in the New York Metropolitan Area

ERIC Educational Resources Information Center

Creel, Stacy L.; Pollicino, Elizabeth B.

2012-01-01

This paper discusses the results of a study that focused on the perceived preparedness of recent graduates. Fifty-five St. John's University MLS students surveyed 348 practitioners in public libraries (181) and school libraries (167) concerning perceived preparedness of recent MLS graduates for the realities of working in libraries. The overriding…

75 FR 52967 - Final Environmental Impact Statement and South Florida and Caribbean Parks Exotic Plant...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-30

... National Historic Park and Ecological Preserve, and Virgin Islands National Park. The FEIS identifies and... resources and values from adverse effects resulting from exotic plant presence and control activities. DATES... Ecological Preserve, and Virgin Islands National Park, 1300 Cruz Bay Creek, St. John, Virgin Islands 00830...

Developing the Profession of School Psychology in Vietnam

ERIC Educational Resources Information Center

Terjesen, Mark D.; Kassay, Kimberly S.; Bolger, Maria

2008-01-01

Building upon a successful prior initial trip to Vietnam in January 2008, students and faculty from St. John's University (STJ) School Psychology program returned to work with the faculty from Hanoi National University of Education (HNUE) in developing the profession of school psychology in that country. The purpose of this trip was twofold: (1)…

20. Photocopy of photograph (Frashers Fotos, Pomona California, 3 July ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

20. Photocopy of photograph (Frashers Fotos, Pomona California, 3 July 1932, original print in possession of National Park Service, Petrified Forest National Park), 'ST. JOHNS HIGH SCHOOL BAND, DEDICATION RIO PUERCO BRIDGE, PETRIFIED FOREST, ARIZONA - JULY 3, 1932.' - Rio Puerco Bridge, Mainline Road, spanning Rio Puerco, Holbrook, Navajo County, AZ

Assessing Nature-Based Recreation to Support Economic Development and Environmental Sustainability Extension Programs

ERIC Educational Resources Information Center

Borisova, Tatiana; Bi, Xiang; Larkin, Sherry; Longanecker, James

2016-01-01

In support of community development, natural resource, and other Extension programs, the research reported here aimed to identify current and potential outdoor recreational opportunities in the St. Johns River Basin, an inland area in northeastern Florida. We identify the characteristics of the visitors participating in the recreational activities…

The Variable-Credit College Writing Course.

ERIC Educational Resources Information Center

VanderBilt, Deborah; Nicolay, Theresa

The introductory writing course, English 101, at St. John Fisher College in Rochester, New York, has gone through several stages in the last decade, changing from a course emphasizing writing in the rhetorical modes to an issue-oriented interdisciplinary course, to, at the present time, a course focusing on the writing process and on collaborative…

Teaching across Cultures: Canada and Qatar

ERIC Educational Resources Information Center

Prowse, Jacqueline; Goddard, J. Tim

2010-01-01

Findings from a comparative case study conducted in Canada and Qatar are presented in this article. The study examined the cultural context of a transnational post-secondary program offered by the Faculty of Business at a Canadian college, with campuses located in both St. John's and Doha. The instructors' perceptions of their students' cultures…

An Integrated Decision-Making Framework for Sustainability Assessment: A Case Study of Memorial University

ERIC Educational Resources Information Center

Waheed, Bushra; Khan, Faisal; Veitch, Brian; Hawboldt, Kelly

2011-01-01

This article presents an overview of the sustainability initiatives at the St. John's campus of Memorial University in Newfoundland and Labrador (Canada). The key initiatives include setting a realistic goal for energy efficiency, becoming carbon neutral, and conducting various research and outreach projects related to sustainability. As…

The Professional Linguist: Language Skills for the Real World

ERIC Educational Resources Information Center

Murata, Mary

2016-01-01

This chapter reports on a compulsory final year employability skills module for Modern Foreign Languages (MFL) undergraduates at York St John University. The "Professional Linguist" aims to equip students with a range of skills which they may need when entering the workplace, whilst underpinning it with theory which would benefit those…

The Experiences of Working-Class College Students Who Became University Presidents

ERIC Educational Resources Information Center

Springer, Mary E.

2012-01-01

Working-class students enter college lacking necessary capital to predict their academic and personal success making college success less likely than for middle class students (Bufton, 2003; Mack, 2006; Paulsen & St. John, 2002; Rose, 1997; Wegner, 1973). This same social class origin helps to define experiences, provides context for…

Experience and Educational Philosophies of Mathematics Teachers in an Urban Public High School

ERIC Educational Resources Information Center

Gaskin, Marjorie Elaine

2017-01-01

This qualitative research study identified the experiences and educational philosophies of mathematics teachers in an urban public high school framed by John Dewey's Theory of Experience and demonstrated by 21st century skills. To facilitate this process, the researcher used semi-structured interviews, direct observations, and collected lesson…

Update to the Atlantic salmon breeding program at the National Cold Water Marine Aquaculture Center

USDA-ARS?s Scientific Manuscript database

The USDA-ARS National Cold Water Marine Aquaculture Center (NCWMAC) in Franklin, ME has been supporting the U.S. coldwater marine aquaculture industry for the past thirteen years by developing a genetically improved North American Atlantic salmon. The St. John's River stock was chosen as the focal ...

Brooks Grease Service, Inc.

EPA Pesticide Factsheets

The EPA is providing notice of a proposed Administrative Penalty Assessment against Brooks Grease Service, Inc., for alleged violations at its vegetable oil collection and storage facility located at or near 218 East James St., Kansas City, KS 66118.

The application of systems thinking concepts, methods, and tools to global health practices: An analysis of case studies.

PubMed

Wilkinson, Jessica; Goff, Morgan; Rusoja, Evan; Hanson, Carl; Swanson, Robert Chad

2018-06-01

This review of systems thinking (ST) case studies seeks to compile and analyse cases from ST literature and provide practitioners with a reference for ST in health practice. Particular attention was given to (1) reviewing the frequency and use of key ST terms, methods, and tools in the context of health, and (2) extracting and analysing longitudinal themes across cases. A systematic search of databases was conducted, and a total of 36 case studies were identified. A combination of integrative and inductive qualitative approaches to analysis was used. Most cases identified took place in high-income countries and applied ST retrospectively. The most commonly used ST terms were agent/stakeholder/actor (n = 29), interdependent/interconnected (n = 28), emergence (n = 26), and adaptability/adaptation (n = 26). Common ST methods and tools were largely underutilized. Social network analysis was the most commonly used method (n = 4), and innovation or change management history was the most frequently used tool (n = 11). Four overarching themes were identified; the importance of the interdependent and interconnected nature of a health system, characteristics of leaders in a complex adaptive system, the benefits of using ST, and barriers to implementing ST. This review revealed that while much has been written about the potential benefits of applying ST to health, it has yet to completely transition from theory to practice. There is however evidence of the practical use of an ST lens as well as specific methods and tools. With clear examples of ST applications, the global health community will be better equipped to understand and address key health challenges. © 2017 John Wiley & Sons, Ltd.

Limnology of Taylor Creek impoundment : with reference to other bodies in Upper St Johns River Basin, Florida

USGS Publications Warehouse

Goolsby, D.A.; McPherson, Benjamin F.

1978-01-01

Taylor Creek Impoundment, on the western part of the upper St. Johns basin, Fla., provides flood control and flow regulation. The 4,000-acre impoundment was first filled in 1969. The water was of relatively poor quality during the first three years of its existence, 1970-72. The impoundment is deep enough for thermal stratification, and a thermocline usually develops at 8 to 10 feet. During 1970-72 the hypolimnion remained anaerobic for more than six months. The poor water quality is attributed to the decomposition of flooded vegetation, of soil organic matter, and to heavy growths of phytoplankton and duckweed stimulated by an abundant supply of nutrients. Since 1972, the quality of the water has improved because of flushing of the impoundment and depletion of leachable nutrients and soil organic matter. The water is now similar in quality to that of nearby Wolf and Jane Green Creeks. Large releases of water may produce velocities great enough to resuspend bottom sediments several miles downstream where Taylor Creek flows into Lake Poinsett. (Woodard-USGS)

Approach to novel functional foods for stress control 4. Regulation of serotonin transporter by food factors.

PubMed

Ito, Mikiko; Haito, Sakiko; Furumoto, Mari; Kawai, Yoshichika; Terao, Junji; Miyamoto, Ken-ichi

2005-11-01

Serotonin transporters (SERTs) are pre-synaptic proteins specialized for the clearance of serotonin following vesicular release at central nervous system (CNS) and enteric nervous system synapses. SERTs are high affinity targets in vivo for antidepressants such as serotonin selective reuptake inhibitors (SSRIs). These include 'medical' psychopharmacological agents such as analgesics and antihistamines, a plant extract called St John's Wort (Hypericum). Osteoclasts are the primary cells responsible for bone resorption. They arise by the differentiation of osteoclast precursors of the monocyte/macrophage lineage. The expression of SERTs was increased in RANKL-induced osteoclast-like cells. Using RANKL stimulation of RAW264.7 cells as a model system for osteoclast differentiation, we studied the direct effects of food factor on serotonin uptake. The SSRIs (fluoxetine and fluvoxamine) inhibited markedly (approximately 95%) in serotonin transport in differentiated osteoclast cells. The major components of St. John's Wort, hyperforin and hypericine were significantly decreased in serotonin transport activity. Thus, a new in vitro model using RANKL-induced osteoclast-like cells may be useful to analyze the regulation of SERT by food factors and SSRIs.

[A Multi-arm Placebo-controlled Study with Glutamic Acid Conducted in Rostock in 1953/1954].

PubMed

Häßler, Frank; Weirich, Steffen

2017-09-01

A Multi-arm Placebo-controlled Study with Glutamic Acid Conducted in Rostock in 1953/1954 Glutamic acid was commonly used in the treatment of intellectually disabled children in the 50s. Koch reported first results of an observation of 140 children treated with glutamic acid in 1952. In this line is the multi-arm placebo-controlled study reported here. The original study protocols were available. 58 children with speech problems who attending a school of special needs received glutamic acid, or vitamin B, or St.-John's-wort. The effect of glutamic acid was in few cases an improvement of attention. On the other hand restlessness and stutter increased. The majority of all reported a weight loss. The treatment with vitamin B showed a positive effect concerning concentration. The treatment with St.-John's wort was stopped caused by headache and vomiting in eight of nine cases. The results of the study reported here are unpublished. The reason may be that until the 60s the effects of glutamic acid in the treatment of intellectually disabled children were in generally overestimated.

Parameter estimation of anisotropic Manning's n coefficient for advanced circulation (ADCIRC) modeling of estuarine river currents (lower St. Johns River)

NASA Astrophysics Data System (ADS)

Demissie, Henok K.; Bacopoulos, Peter

2017-05-01

A rich dataset of time- and space-varying velocity measurements for a macrotidal estuary was used in the development of a vector-based formulation of bottom roughness in the Advanced Circulation (ADCIRC) model. The updates to the parallel code of ADCIRC to include directionally based drag coefficient are briefly discussed in the paper, followed by an application of the data assimilation (nudging analysis) to the lower St. Johns River (northeastern Florida) for parameter estimation of anisotropic Manning's n coefficient. The method produced converging estimates of Manning's n values for ebb (0.0290) and flood (0.0219) when initialized with uniform and isotropic setting of 0.0200. Modeled currents, water levels and flows were improved at observation locations where data were assimilated as well as at monitoring locations where data were not assimilated, such that the method increases model skill locally and non-locally with regard to the data locations. The methodology is readily transferrable to other circulation/estuary models, given pre-developed quality mesh/grid and adequate data available for assimilation.

Flood of April and May 2008 in Northern Maine

USGS Publications Warehouse

Lombard, Pamela J.

2010-01-01

Severe flooding occurred in Aroostook and Penobscot Counties in northern Maine between April 28 and May 1, 2008, and damage was extensive in the town of Fort Kent. Aroostook County was declared a Federal disaster area on May 9, and the declaration was expanded to include Penobscot County on May 16-qualifying the entire region for federal assistance. Water in the St. John River peaked at 30.17 feet in Fort Kent (5 feet above flood stage), hit the low steel of the International Bridge connecting Fort Kent to New Brunswick, caused closure of international bridges in Fort Kent, Van Buren, and Hamlin and came within inches of the top of a 30-foot-high earthen dike constructed to protect the downtown area of Fort Kent. Longterm streamgages with 25 to 84 years of record on the Big Black, St. John, Allagash, Fish, and Aroostook Rivers recorded maximum streamflows for their respective periods of record. Northern Maine experienced major floods in 1923, 1973, 1974, 1979, and 1983 (Maloney and Bartlett, 1991). All of these floods were in late April or early May when heavy rain combined with snowmelt runoff.

What is the main driver of atmospheric CO2 dynamic: ocean or permafrost?

NASA Astrophysics Data System (ADS)

Zimov, S. A.; Zimov, N.

2010-12-01

Majority have assumed that during the Last Deglaciation (LD) ocean was a strong source of carbon (C) transporting hundreds of gigatons of C into the terrestrial and atmospheric storages. Increase in the δ13C of foraminifera shells during the LD by 0.3-0.4 per mil considered as an evidence of such a source. However terrestrial and oceanic branches of the biological carbon cycle have very similar carbon isotopic signatures and carbon storage capacities. So the same δ13C increase could be caused by an oceanic bio-productivity increase and the increase of C in bottom sediments (Brovkin et al. 2002). Additionally it has been shown experimentally that at 90 ppmv increase in atmospheric CO2, due to changes in the concentration of carbonate ions in sea water, would cause the δ13C of foraminifera shells to increase by at least 0.25-0.5 per mil (Spero et al. 1997). At all stable parameters to equilibrate for 90 ppm CO2 increase in the atmosphere ocean inorganic C reservoir should have increased by 1800 Gt C (Sigman et al. 2000). Therefore it is very hard to find a mechanism which would allow ocean in LD to release carbon instead of absorbing it, and such a mechanism haven’t been found so far. Methane (CH4) produced by steppe-tundra biome (ST) soil thawing has a unique isotopic signal depleted in all isotopes. Inclusion of this source into a model of the atmospheric methane isotope budget allowed us to reconstruct the dynamics of methane’s main sources. Results indicated that thawing of ST soils during the deglaciation, were the largest methane source and resulted in 255 Gt C emitted in the form of CH4 to the atmosphere (Zimov, see AGU 2010). When soil turns anaerobic only minor portion of soil C converts into CH4. Bigger portion of ST didn’t turn anaerobic at all and all decomposing C was turned into CO2. Besides that part of the soil CH4 flux was consumed by methanotrophs. Therefore C storage in ST soils were many times higher then CH4 emission into the atmosphere. In LD bigger portion of ST soils thawed and after drainage and aeration lost its carbon. Based on field experiments we calculated the portion of total ST soils C which transforms into CH4, and using the model describing the C accumulation in ST soils (Zimov et al. 2009) estimated that at CH4 emission of 255 Gt C , emission of CO2 was ~3000 Gt C. From this follows that for the duration of glaciation C storage in ocean strongly reduced. As follows from CH4 dynamic most intensive C release from permafrost was in Bolling-Allerod and Pre-Boreal, but at that time increased ocean ventilation and bioproductivity (Skinner et al. 2010). Depleted with C Ocean absorbed CO2 from atmosphere and compensated for emission from permafrost so rise in atmospheric CO2 concentrations didn’t occur at that time.

A potential approach for low flow selection in water resource supply and management

NASA Astrophysics Data System (ADS)

Ouyang, Ying

2012-08-01

SummaryLow flow selections are essential to water resource management, water supply planning, and watershed ecosystem restoration. In this study, a new approach, namely the frequent-low (FL) approach (or frequent-low index), was developed based on the minimum frequent-low flow or level used in minimum flows and/or levels program in northeast Florida, USA. This FL approach was then compared to the conventional 7Q10 approach for low flow selections prior to its applications, using the USGS flow data from the freshwater environment (Big Sunflower River, Mississippi) as well as from the estuarine environment (St. Johns River, Florida). Unlike the FL approach that is associated with the biological and ecological impacts, the 7Q10 approach could lead to the selections of extremely low flows (e.g., near-zero flows) that may hinder its use for establishing criteria to prevent streams from significant harm to biological and ecological communities. Additionally, the 7Q10 approach could not be used when the period of data records is less than 10 years by definition while this may not the case for the FL approach. Results from both approaches showed that the low flows from the Big Sunflower River and the St. Johns River decreased as time elapsed, demonstrating that these two rivers have become drier during the last several decades with a potential of salted water intrusion to the St. Johns River. Results from the FL approach further revealed that the recurrence probability of low flow increased while the recurrence interval of low flow decreased as time elapsed in both rivers, indicating that low flows occurred more frequent in these rivers as time elapsed. This report suggests that the FL approach, developed in this study, is a useful alternative for low flow selections in addition to the 7Q10 approach.

TRPC6 channel-mediated neurite outgrowth in PC12 cells and hippocampal neurons involves activation of RAS/MEK/ERK, PI3K, and CAMKIV signaling.

PubMed

Heiser, Jeanine H; Schuwald, Anita M; Sillani, Giacomo; Ye, Lian; Müller, Walter E; Leuner, Kristina

2013-11-01

The non-selective cationic transient receptor canonical 6 (TRPC6) channels are involved in synaptic plasticity changes ranging from dendritic growth, spine morphology changes and increase in excitatory synapses. We previously showed that the TRPC6 activator hyperforin, the active antidepressant component of St. John's wort, induces neuritic outgrowth and spine morphology changes in PC12 cells and hippocampal CA1 neurons. However, the signaling cascade that transmits the hyperforin-induced transient rise in intracellular calcium into neuritic outgrowth is not yet fully understood. Several signaling pathways are involved in calcium transient-mediated changes in synaptic plasticity, ranging from calmodulin-mediated Ras-induced signaling cascades comprising the mitogen-activated protein kinase, PI3K signal transduction pathways as well as Ca(2+) /calmodulin-dependent protein kinase II (CAMKII) and CAMKIV. We show that several mechanisms are involved in TRPC6-mediated synaptic plasticity changes in PC12 cells and primary hippocampal neurons. Influx of calcium via TRPC6 channels activates different pathways including Ras/mitogen-activated protein kinase/extracellular signal-regulated kinases, phosphatidylinositide 3-kinase/protein kinase B, and CAMKIV in both cell types, leading to cAMP-response element binding protein phosphorylation. These findings are interesting not only in terms of the downstream targets of TRPC6 channels but also because of their potential to facilitate further understanding of St. John's wort extract-mediated antidepressant activity. Alterations in synaptic plasticity are considered to play an important role in the pathogenesis of depression. Beside several other proteins, TRPC6 channels regulate synaptic plasticity. This study demonstrates that different pathways including Ras/MEK/ERK, PI3K/Akt, and CAMKIV are involved in the improvement of synaptic plasticity by the TRPC6 activator hyperforin, the antidepressant active constituent of St. John's wort extract. © 2013 International Society for Neurochemistry.

Geomorphic origin of Merritt Island-Cape Canaveral, Florida, USA: A paleodelta of the reversed St. Johns River?

NASA Astrophysics Data System (ADS)

Adams, Peter N.

2018-04-01

The Merritt Island-Cape Canaveral (MICCSC) sedimentary complex consists of a series of adjacent, non-conformable, beach ridge sets that suggest a multi-phase constructional history, but the feature's geomorphic and sedimentary origins are not well-understood. In spite of its notable sedimentary volume (surface area = 1200 km2), the MICCSC lacks a clear sediment source, or supply mechanism, to explain its presence today. Previously published U/Th, radiocarbon and OSL dates indicate that beach ridge deposition was active during MIS 5 (130-80 ka) on Merritt Island, but has occurred over a shorter, younger time interval on Cape Canaveral proper (6 ka to present). In this paper, it is proposed that the MICCSC is an abandoned paleodelta whose fluvial source provided a sediment supply sufficient for coastal progradation. Although the MICCSC, today, does not receive an appreciable sediment supply, the nearly 23,000 km2 drainage basin of the St. Johns River may well have provided such a sediment supply during MIS 5 times. This low-gradient fluvial system currently empties to the Atlantic Ocean some 200 km north of the MICCSC (near Jacksonville, Florida) but may have flowed southward during the time of MICCSC sedimentary construction, then experienced flow reversal since MIS 5 times. Three possible uplift mechanisms are proposed to explain the northward down-tilting that may have reversed the flow direction of the St. Johns, abandoning deltaic construction of the MICCSC: (1) karst-driven, flexural isostatic uplift in response to carbonate rock dissolution in central Florida, (2) glacio-hydro-isostatic tilting/back-tilting cycles during loading and unloading of the Laurentide ice sheet during the Pleistocene, and (3) mantle convection-driven dynamic topography operating within southeastern North America since the Pliocene. This example testifies to the sensitivity of low-gradient, low-relief landscapes to various sources of uplift, be they isostatic or otherwise.

Final Nevada Training Initiative Environmental Assessment

DTIC Science & Technology

2003-07-01

Impact StAtement, pursuaoltO the National Environmental Policy Ac1 of 1969 (Public Law 91-190) is not "i:§ o .*= : ~-Dale z.g:n FIND I G OF NO SIGNIFICANT...July 2003 Figure 2-12 Alternatives 2A and 2B Facility Locations Munitions storage area DJ~==;===== o ...Process Drivers Analyzed in this EA Resources C on st ru ct io n O pe ra tio ns Yes No Air Quality Ä Ä Ä Biological Resources Ä Ä Cultural

Environmental Assessment Anti-Terrorism/Force Protection Travis Air Force Base, California

DTIC Science & Technology

2003-09-01

Forbes Street and De Ronde Drive 0630 to 0900 and 1145 to 1630 weekdays POV, school buses, school children and their parents 225 POV privately...03L North Gate- Vacaville Gate Air Base Pkwy. Ra gsi de St. Hangar Ave. Travis Ave. Bu rg an B lvd . Hickam Ave. Fi rs t S t. Broadway St. Ca nn on D...Facility Addition and Alteration to Life Support Shop Taxiway Lima Repairs Electrical, Utilities, and Supporting Infrastructure* Engine Storage Facility

Basic Techniques in Mammalian Cell Tissue Culture.

PubMed

Phelan, Katy; May, Kristin M

2016-11-01

Cultured mammalian cells are used extensively in cell biology studies. It requires a number of special skills in order to be able to preserve the structure, function, behavior, and biology of the cells in culture. This unit describes the basic skills required to maintain and preserve cell cultures: maintaining aseptic technique, preparing media with the appropriate characteristics, passaging, freezing and storage, recovering frozen stocks, and counting viable cells. © 2016 by John Wiley & Sons, Inc. Copyright © 2016 John Wiley & Sons, Inc.

Mammalian Cell Tissue Culture.

PubMed

Phelan, Katy; May, Kristin M

2017-07-11

Cultured mammalian cells are used extensively in the field of human genetics. It requires a number of special skills in order to be able to preserve the structure, function, behavior, and biology of the cells in culture. This unit describes the basic skills required to maintain and preserve cell cultures: maintaining aseptic technique, preparing media with the appropriate characteristics, passaging, freezing and storage, recovering frozen stocks, and counting viable cells. © 2017 by John Wiley & Sons, Inc. Copyright © 2017 John Wiley & Sons, Inc.

Impact of metal and anion substitutions on the hydrogen storage properties of M-BTT metal-organic frameworks.

PubMed

Sumida, Kenji; Stück, David; Mino, Lorenzo; Chai, Jeng-Da; Bloch, Eric D; Zavorotynska, Olena; Murray, Leslie J; Dincă, Mircea; Chavan, Sachin; Bordiga, Silvia; Head-Gordon, Martin; Long, Jeffrey R

2013-01-23

Microporous metal-organic frameworks are a class of materials being vigorously investigated for mobile hydrogen storage applications. For high-pressure storage at ambient temperatures, the M(3)[(M(4)Cl)(3)(BTT)(8)](2) (M-BTT; BTT(3-) = 1,3,5-benzenetristetrazolate) series of frameworks are of particular interest due to the high density of exposed metal cation sites on the pore surface. These sites give enhanced zero-coverage isosteric heats of adsorption (Q(st)) approaching the optimal value for ambient storage applications. However, the Q(st) parameter provides only a limited insight into the thermodynamics of the individual adsorption sites, the tuning of which is paramount for optimizing the storage performance. Here, we begin by performing variable-temperature infrared spectroscopy studies of Mn-, Fe-, and Cu-BTT, allowing the thermodynamics of H(2) adsorption to be probed experimentally. This is complemented by a detailed DFT study, in which molecular fragments representing the metal clusters within the extended solid are simulated to obtain a more thorough description of the structural and thermodynamic aspects of H(2) adsorption at the strongest binding sites. Then, the effect of substitutions at the metal cluster (metal ion and anion within the tetranuclear cluster) is discussed, showing that the configuration of this unit indeed plays an important role in determining the affinity of the framework toward H(2). Interestingly, the theoretical study has identified that the Zn-based analogs would be expected to facilitate enhanced adsorption profiles over the compounds synthesized experimentally, highlighting the importance of a combined experimental and theoretical approach to the design and synthesis of new frameworks for H(2) storage applications.

STS-121: Discovery Launch Postponement MMT Briefing

NASA Technical Reports Server (NTRS)

2006-01-01

Bruce Buckingham from NASA Public Affairs introduces the panel who consist of: John Shannon, MMT chairman JSC; Mike Leinbach, NASA Launch Director; and 1st Lieutenant Kaleb Nordren, USAF 45th Weather Squadron. An opening statement is given from John Shannon on the postponement of the launch due to thunderstorms. Mike Leinbach also elaborates on the weather and talks about scrubbing two hours early, draining the vehicle, and reloading the hydrogen for the fuel cells for a possible launch attempt on Tuesday morning. Norden gives his weather forecast for Tuesday and Wednesday. Questions from the media on launch attempts, weather, and the cost of the scrub are addressed.

EMASS (tm): An expandable solution for NASA space data storage needs

NASA Technical Reports Server (NTRS)

Peterson, Anthony L.; Cardwell, P. Larry

1992-01-01

The data acquisition, distribution, processing, and archiving requirements of NASA and other U.S. Government data centers present significant data management challenges that must be met in the 1990's. The Earth Observing System (EOS) project alone is expected to generate daily data volumes greater than 2 Terabytes (2(10)(exp 12) Bytes). As the scientific community makes use of this data their work product will result in larger, increasingly complex data sets to be further exploited and managed. The challenge for data storage systems is to satisfy the initial data management requirements with cost effective solutions that provide for planned growth. This paper describes the expandable architecture of the E-Systems Modular Automated Storage System (EMASS (TM)), a mass storage system which is designed to support NASA's data capture, storage, distribution, and management requirements into the 21st century.

EMASS (trademark): An expandable solution for NASA space data storage needs

NASA Technical Reports Server (NTRS)

Peterson, Anthony L.; Cardwell, P. Larry

1991-01-01

The data acquisition, distribution, processing, and archiving requirements of NASA and other U.S. Government data centers present significant data management challenges that must be met in the 1990's. The Earth Observing System (EOS) project alone is expected to generate daily data volumes greater than 2 Terabytes (2 x 10(exp 12) Bytes). As the scientific community makes use of this data, their work will result in larger, increasingly complex data sets to be further exploited and managed. The challenge for data storage systems is to satisfy the initial data management requirements with cost effective solutions that provide for planned growth. The expendable architecture of the E-Systems Modular Automated Storage System (EMASS(TM)), a mass storage system which is designed to support NASA's data capture, storage, distribution, and management requirements into the 21st century is described.

Cytosolic glyceraldehyde-3-phosphate dehydrogenases play crucial roles in controlling cold-induced sweetening and apical dominance of potato (Solanum tuberosum L.) tubers.

PubMed

Liu, Tengfei; Fang, Hui; Liu, Jun; Reid, Stephen; Hou, Juan; Zhou, Tingting; Tian, Zhendong; Song, Botao; Xie, Conghua

2017-12-01

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an important enzyme that functions in producing energy and supplying intermediates for cellular metabolism. Recent researches indicate that GAPDHs have multiple functions beside glycolysis. However, little information is available for functions of GAPDHs in potato. Here, we identified 4 putative cytosolic GAPDH genes in potato genome and demonstrated that the StGAPC1, StGAPC2, and StGAPC3, which are constitutively expressed in potato tissues and cold inducible in tubers, encode active cytosolic GAPDHs. Cosuppression of these 3 GAPC genes resulted in low tuber GAPDH activity, consequently the accumulation of reducing sugars in cold stored tubers by altering the tuber metabolite pool sizes favoring the sucrose pathway. Furthermore, GAPCs-silenced tubers exhibited a loss of apical dominance dependent on cell death of tuber apical bud meristem (TAB-meristem). It was also confirmed that StGAPC1, StGAPC2, and StGAPC3 interacted with the autophagy-related protein 3 (ATG3), implying that the occurrence of cell death in TAB-meristem could be induced by ATG3 associated events. Collectively, the present research evidences first that the GAPC genes play crucial roles in diverse physiological and developmental processes in potato tubers. © 2017 John Wiley & Sons Ltd.

Allelic variations and differential expressions detected at quantitative trait loci for salt stress tolerance in wheat.

PubMed

Oyiga, Benedict C; Sharma, Ram C; Baum, Michael; Ogbonnaya, Francis C; Léon, Jens; Ballvora, Agim

2018-05-01

The increasing salinization of agricultural lands is a threat to global wheat production. Understanding of the mechanistic basis of salt tolerance (ST) is essential for developing breeding and selection strategies that would allow for increased wheat production under saline conditions to meet the increasing global demand. We used a set that consists of 150 internationally derived winter and facultative wheat cultivars genotyped with a 90K SNP chip and phenotyped for ST across three growth stages and for ionic (leaf K + and Na +  contents) traits to dissect the genetic architecture regulating ST in wheat. Genome-wide association mapping revealed 187 Single Nucleotide Polymorphism (SNPs) (R 2  = 3.00-30.67%), representing 37 quantitative trait loci (QTL), significantly associated with the ST traits. Of these, four QTL on 1BS, 2AL, 2BS and 3AL were associated with ST across the three growth stages and with the ionic traits. Novel QTL were also detected on 1BS and 1DL. Candidate genes linked to these polymorphisms were uncovered, and expression analyses were performed and validated on them under saline and non-saline conditions using transcriptomics and qRT-PCR data. Expressed sequence comparisons in contrasting ST wheat genotypes identified several non-synonymous/missense mutation sites that are contributory to the ST trait variations, indicating the biological relevance of these polymorphisms that can be exploited in breeding for ST in wheat. © 2017 The Authors. Plant, Cell & Environment published by JohnWiley & Sons Ltd.

The empirical Bayes estimators of fine-scale population structure in high gene flow species.

PubMed

Kitada, Shuichi; Nakamichi, Reiichiro; Kishino, Hirohisa

2017-11-01

An empirical Bayes (EB) pairwise F ST estimator was previously introduced and evaluated for its performance by numerical simulation. In this study, we conducted coalescent simulations and generated genetic population structure mechanistically, and compared the performance of the EBF ST with Nei's G ST , Nei and Chesser's bias-corrected G ST (G ST_NC ), Weir and Cockerham's θ (θ WC ) and θ with finite sample correction (θ WC_F ). We also introduced EB estimators for Hedrick' G' ST and Jost' D. We applied these estimators to publicly available SNP genotypes of Atlantic herring. We also examined the power to detect the environmental factors causing the population structure. Our coalescent simulations revealed that the finite sample correction of θ WC is necessary to assess population structure using pairwise F ST values. For microsatellite markers, EBF ST performed the best among the present estimators regarding both bias and precision under high gene flow scenarios (FST≤0.032). For 300 SNPs, EBF ST had the highest precision in all cases, but the bias was negative and greater than those for G ST_NC and θ WC_F in all cases. G ST_NC and θ WC_F performed very similarly at all levels of F ST . As the number of loci increased up to 10 000, the precision of G ST_NC and θ WC_F became slightly better than for EBF ST for cases with FST≥0.004, even though the size of the bias remained constant. The EB estimators described the fine-scale population structure of the herring and revealed that ~56% of the genetic differentiation was caused by sea surface temperature and salinity. The R package finepop for implementing all estimators used here is available on CRAN. © 2017 The Authors. Molecular Ecology Resources Published by John Wiley & Sons Ltd.

The School Car: Bringing the Three R's to Newfoundland's Remote Railway Settlements (1936-1942).

ERIC Educational Resources Information Center

Noseworthy, Randy P.

During the mid-1930s, the main line of the Newfoundland (Canada) Railway stretched 547 miles from St. John's to Port aux Basques, and railway workers and their families lived along the line in small isolated settlements. The provincial department of education, the Newfoundland Railway, and the Anglo-Newfoundland Development Company devised an…

Estimation of dynamic load of mercury in a river with BASINS-HSPF model

Treesearch

Ying Ouyang; John Higman; Jeff Hatten

2012-01-01

Purpose Mercury (Hg) is a naturally occurring element and a pervasive toxic pollutant. This study investigated the dynamic loads of Hg from the Cedar-Ortega Rivers watershed into the Lower St. Johns River (LSJR), Florida, USA, using the better assessment science integrating point and nonpoint sources (BASINS)-hydrologic simulation program - FORTRAN (HSPF) model....

Diel activity patterns of major species of adult mosquitoes and ULV spraying impacts in St. John's County, Florida

USDA-ARS?s Scientific Manuscript database

Knowledge of daily activity patterns in adult mosquitoes can be used to determine the best time to apply adulticides for mosquito control. Many factors influence these activity patterns, including migration, hormonal cycles in the mosquito, hunger, and the need to lay eggs. In this study, FL scien...

Using ePortfolios to Assess Student Achievement within an Online Library and Information Studies Program

ERIC Educational Resources Information Center

Angel, Christine M.; Robinson, Gina

2017-01-01

As a result of suggestions from the American Library Association (ALA) the Division of Library and Information Science (DLIS) program at St. John's University implemented an end-of-program electronic portfolio (ePortfolio) requirement. The purpose of this ePortfolio is to provide information on student proficiency in the eight ALA core…

ACHP | Q&A | The ACHP Interview: Dr. Julia King, associate professor of

Science.gov Websites

specific nav links Home arrow The ACHP Interview: Dr. Julia King, associate professor of archaeology and anthropology at St. Mary’s College of Maryland, expert member ACHP The ACHP Interview: Dr. Julia King With the recent Society for Historical Archaeology conference concluded, and former chairman John Nau

Securing the Aviation Transportation System

DTIC Science & Technology

2007-12-01

accessed 27 May 2007) 13 Robert W. Poole, Jr., “ Airport Security : Time for a New Model,” Reason Foundation online article, January 2006, Available from...15 Robert W. Poole, Jr., “ Airport Security : Time for a New Model,” Reason Foundation online article, January 2006...commercial jetliners. 24 Peter St. John, Air Piracy, Airport Security , and International Terrorism

Paddle Your Own Canoe: Metaphors for Teaching between the Tides

ERIC Educational Resources Information Center

Wright, W. Alan; Monette, Marie-Jeanne; Hamilton, Beverley

2010-01-01

Nearly twenty college and university voyageurs hailing from Atlantic Canada to the Pacific Coast and points in between, as well as intrepid pedagogues from institutions of higher education from Asia and Australia rendezvous at the Small Craft Aquatic Centre in Fredericton, New Brunswick, on the shores of the St. John River. The sun shines brightly…

Deliverance from the "Dark Night of the Soul"

ERIC Educational Resources Information Center

Kinnier, Richard T.; Dixon, Andrea L.; Scheidegger, Corey; Lindberg, Brent

2009-01-01

For many individuals, spiritual inspiration, clarity, or epiphany is often preceded by a "dark night of the soul". St. John of the Cross, a Spanish mystic of the 16th century, first described the concept. Today, the phrase "dark night of the soul" is usually associated with the crisis part of the journey to enlightenment. This article defines and…

Manpower Impact Assessment Model (MIAM). An Analytic Model for Assessing the Effect of Supply Policy Changes on Manpower Requirements at Retail Supply Activities

DTIC Science & Technology

1984-09-01

to Management Science (Third Edition). St. Paul: West Publishing Co., 1982. 2. Bennett, John L. (Editor). Building Decision Support Systems. Reading...Starts 700 DCCs 5000 Units Inventoried 50000 103 * * Bibliography /, 1. Anderson, David R., Dennis J. Sweeney, and Thomas A. Williams. An Introduction

Remote sensing of wetlands, marshes, and shorelines in Michigan including St. John's Marsh

NASA Technical Reports Server (NTRS)

Lowe, D. S.

1976-01-01

Remote sensing data are used to show the strategic relationship of the endangered marsh to population centers of SE Michigan. The potential ecological consequences and the impact of past development and changing lake levels are discussed. Applications of remote sensing are presented showing its usefulness for preparing statewide infrared wetland and forest mapping.

76 FR 39890 - St. Johns National Wildlife Refuge, FL; Draft Comprehensive Conservation Plan and Environmental...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-07

... would determine the size, seasonality, and frequency of prescribed fires to benefit rail species. We... response. We would work to restore the hydrologic setting to benefit marsh birds and determine the role of..., cattle grazing, and/ or other forms of vegetation maintenance to benefit this species on the Bee Line...

Ceratonia siliqua L.: carob

Treesearch

Wayne D. Shepperd

2008-01-01

Ceratonia siliqua L. - carob, St. John's bread, or locust - is a small to medium-sized broadleaf, evergreen tree that may grow to 20 m in height under ideal climatic conditions (Catarino 1993) but usually reaches heights of 8 to 15 m (Goor and Barney 1968). Carob is thought to be a tropical plant that has adapted well to Mediterranean climates by utilizing its...

Get out of Fines Free: Recruiting Student Usability Testers via Fine Waivers

ERIC Educational Resources Information Center

Hockenberry, Benjamin; Blackburn, Kourtney

2016-01-01

St. John Fisher College's Lavery Library's Access Services and Systems departments began a pilot project in which students with overdue fines tested usability of library Web sites in exchange for fine waivers. Circulation staff promoted the program and redeemed fine waiver vouchers at the Checkout Desk, while Systems staff administered testing and…

46 CFR 7.95 - St. Johns Point, FL to Miami Beach, FL.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Inlet Entrance Lighted Whistle Buoy “2”); thence to Jupiter Island bearing approximately 180° true. (h) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet. (i) A line drawn from the seaward extremity of...

46 CFR 7.95 - St. Johns Point, FL to Miami Beach, FL.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Inlet Entrance Lighted Whistle Buoy “2”); thence to Jupiter Island bearing approximately 180° true. (h) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet. (i) A line drawn from the seaward extremity of...

46 CFR 7.95 - St. Johns Point, FL to Miami Beach, FL.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Inlet Entrance Lighted Whistle Buoy “2”); thence to Jupiter Island bearing approximately 180° true. (h) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet. (i) A line drawn from the seaward extremity of...

46 CFR 7.95 - St. Johns Point, FL to Miami Beach, FL.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Inlet Entrance Lighted Whistle Buoy “2”); thence to Jupiter Island bearing approximately 180° true. (h) A line drawn from the seaward extremity of Jupiter Inlet North Jetty to the northeast extremity of the concrete apron on the south side of Jupiter Inlet. (i) A line drawn from the seaward extremity of...

Adaptability of selected tree species planted in Hawaii forests

Treesearch

Robert E. Nelson; Thomas H. Schubert

1972-01-01

Many tree species have been introduced into Hawaii from around the world (Bryan and Walker i962, Hillebrand 1965, St. John 1973). Trial introductions of new species for various forestry purposes began in the 19th century and are still continuing. Walker (1887), Judd (1915); Lyon (1929), Zschokke (1930), Bryan (1947), and Whitesell (1971, 1974), among others, have...

Psychologizing and the Anti-Psychologist: Dewey, Lacan, and Contemporary Art Education

ERIC Educational Resources Information Center

Thomas, Beth A.

2012-01-01

Art education throughout the 20th and into the 21st century has drawn on both psychology and psychoanalysis to support approaches to teaching and learning in the arts. This article examines the concept of "psychologizing" as it appears in the writing of psychologist/philosopher John Dewey (1859-1952) and psychiatrist/psychoanalyst Jacques Lacan…

Our Schools--Our Hope: Reflections on Catholic Identity from the 2011 Catholic Higher Education Collaborative Conference

ERIC Educational Resources Information Center

O'Connell, David M.; Harrington, Donald J.; Monsegur, Barbara L.; Vogtner, Karen; Burnford, Thomas W.; Krebbs, Mary Jane

2012-01-01

These proceedings include selected presentations on Catholic identity by six participants of the 2011 Catholic Higher Education Collaborative (CHEC) Conference on Catholic Identity at The Catholic University of America (CUA). The conference, jointly sponsored by CUA and St. John's University, is the fourth in a series of five national conferences…

2 University Chiefs Caught up in a Wall Street Meltdown

ERIC Educational Resources Information Center

Fain, Paul

2008-01-01

This article reports that a pair of university presidents is among the people feeling the heat from the collapse of the investment bank Bear Stearns. Henry S. Bienen, president of Northwestern University, and the Rev. Donald J. Harrington, president of St. John's University, in New York, were among the 12 members of the Bear Stearns Companies'…

Strengthening Career and Technical Education and 21st Century Skills in Philadelphia

ERIC Educational Resources Information Center

Philadelphia Youth Network, 2009

2009-01-01

In Spring 2007, the John S. and James L. Knight Foundation awarded funds to the Philadelphia Youth Network (PYN) to undertake an analysis of Career and Technical Education (CTE) in Philadelphia, and to make recommendations on how CTE and other forms of career-connected education could better align with Philadelphia standards for college and career…

The Challenges for Sub-Saharan Africa. Sir John Crawford Memorial Lecture (1st, Washington, DC, November 1, 1985).

ERIC Educational Resources Information Center

McNamara, Robert S.

The economic crisis in Sub-Saharan Africa threatens to condemn an entire continent to human misery unless stronger action is taken to control population growth, reverse ecological devastation, eliminate distortions in domestic economic policies, and increase external development finance. Substantial increases in financial assistance to Africa are…

Quantification of Shallow Groundwater Nutrient Dynamics in Septic Areas

Treesearch

Ying Ouyang; Jia-En Zhang

2012-01-01

Of all groundwater pollution sources, septic systems are the second largest source of groundwater nitrate contamination in USA. This study investigated shallow groundwater (SGW) nutrient dynamics in septic areas at the northern part of the Lower St. Johns River Basin, Florida, USA. Thirty-five SGW-monitoring wells, located at nine different urban areas served by septic...

The Design and Implementation of a Career Orientation Course for Undergraduate Majors

ERIC Educational Resources Information Center

Freeman, Edward

2012-01-01

Over the past several years I have taught a career orientation course at St. John Fisher College. This course was designed to increase student awareness of potential careers following their undergraduate studies in our Biology program. Additionally, the course has also been used as a model for similar experiences in our Psychology, Chemistry,…

Teacher Candidates Reconcile "The Child and the Curriculum" with "No Child Left Behind"

ERIC Educational Resources Information Center

Samuel, Francis A.; Suh, Bernadyn

2012-01-01

What relevance does John Dewey have for students and teachers of the 21st century? Can his educational philosophy be reconciled with "No Child Left Behind" (NCLB) and its emphasis on accountability and high-stakes testing? In this article, the authors discuss Dewey's ideas about the child and the curriculum; delineate how teacher…

District Composite Report: St. John the Baptist Parish. 2002-2003.

ERIC Educational Resources Information Center

Louisiana State Department of Education, 2004

2004-01-01

Up to six years of data (the current year and the five previous years where available) are presented in Louisiana's District Composite Report. Each year, this report is updated by adding the most current year?s data and deleting the data that are more than six years old. Incorporating longitudinal data in the District Composite Report enables…

THREE-DIMENSIONAL MODELING OF COHESIVE SEDIMENT TRANSPORT IN A PARTIALLY STRATIFIED MICRO-TIDAL ESTUARY TO ASSESS EFFECTIVENESS OF SEDIMENT TRAPS

EPA Science Inventory

The three-dimensional (3D) finite difference model Environmental Fluid Dynamics Code (EFDC) was used to simulate the hydrodynamics and sediment transport in a partially stratified micro-tidal estuary. The estuary modeled consisted of a 16-km reach of the St. Johns River, Florida,...

IFLA General Conference, 1987. Division of Management and Technology. Library Building and Equipment Section. Information Technology Section. Papers.

ERIC Educational Resources Information Center

International Federation of Library Associations, The Hague (Netherlands).

The six papers in this collection focus on library buildings and equipment and information technology: (1) "Library Equipment in a Changing Library Environment" (Margaret Beckman, Canada); (2) "The New Building for the British Library" (Colin St. John Wilson, United Kingdom); (3) "User Interaction with Online Catalogue" (Stephen Walker, United…

Healthy Brain Development: Precursor to Learning. National Health/Education Consortium (1st, Baltimore, Maryland, December 6, 1990).

ERIC Educational Resources Information Center

Institute for Educational Leadership, Washington, DC.

This report presents the proceedings of a consortium at which leading developmental neuroscientists from across the United States and Canada met at Johns Hopkins University to explore the relationship between children's health and learning and to propose policy changes. Early brain development and its relationship to intelligence, learning, and…

Celebrating Our Elders Who Led Us across the Bridge: A Call to Action for the Academy

ERIC Educational Resources Information Center

Parham, William D.; Clauss-Ehlers, Caroline S.

2016-01-01

This issue of the "Journal of Multicultural Counseling and Development" launches an inaugural series, Hearing Our Elders, and introduces the Honorable Congressman John Lewis as the series' 1st guest. The social, environmental, and political contexts within which the civil rights and multicultural counseling movements were shaped and…

Redescripcion de la hembra y descripcion del macho de Pseudomethoca argyrocephala (Hymenoptera Mutillidae)

Treesearch

J.A. Genaro; J.A. Torres

1999-01-01

La especie Pseudomethoca argyrocephala fue descrita muy brevemente a partir de una hembra colectada en St. John, Islas Vfrgenes (Gerstaecker, 1874). Su presencia, inadvertida por la ausencia de ejemplares en las principales colecciones y la deposicion del holotipo en algun museo de Alemania, posiblemente motivo la omision en una clave para las especies antillanas (...

Floods in Florida due to Tropical Storm Fay, August 15 through September 26, 2008

USGS Publications Warehouse

Verdi, Richard J.; Holt, Sandra L.

2010-01-01

Weather conditions produced by Tropical Storm Fay from August 15 through September 26, 2008, caused historic flooding, spawned 19 tornadoes, inflicted $390 million in damages, and contributed to five deaths in Florida. This slow-moving system made four separate landfalls accompanied by extensive rainfall and some wind-induced effects. Major flooding with new period-of-record instantaneous peaks and maximum monthly mean streamflows were reported throughout the Ochlockonee and St. Marks Rivers in the Florida Panhandle and the St. Marys, St. Johns, Econlockhatchee, and Wekiva Rivers in northeastern Florida. A total of 147 field crews from the U.S. Geological Survey in Florida made flood measurements immediately following passage of Tropical Storm Fay and continued to monitor high-water conditions for the subsequent 24 days. These measurements were used to verify and document the ratings and the peaks of this climatic event throughout the State.

Solar-heating and hot water system--St. Louis, Missouri

NASA Technical Reports Server (NTRS)

1981-01-01

Sunlight supplies about half heat energy needs of small office. System includes six tilt-adjustable commercial collectors and 1,000 gallon energy storage tank. Report contains description of system and components, drawings and photographs, manufacturer's data, and related material.

COMPLEMENTARITY OF ECOLOGICAL GOAL FUNCTIONS

EPA Science Inventory

This paper summarizes, in the framework of network environ analysis, a set of analyses of energy-matter flow and storage in steady state systems. The network perspective is used to codify and unify ten ecological orientors or external principles: maximum power (Lotka), maximum st...

Evolving magma storage conditions beneath Mount St. Helens inferred from chemical variations in melt inclusions from the 1980-1986 and current (2004-2006) eruptions: Chapter 33 in A volcano rekindled: the renewed eruption of Mount St. Helens, 2004-2006

USGS Publications Warehouse

Blundy, Jon; Cashman, Katharine V.; Berlo, Kim; Sherrod, David R.; Scott, William E.; Stauffer, Peter H.

2008-01-01

O contents, consistent with magma extraction from shallow depths. Highly enriched Li in melt inclusions suggests that vapor transport of Li is a characteristic feature of Mount St. Helens. Melt inclusions from the current eruption have subtly different trace-element chemistry from all but one of the 1980-86 melt inclusions, with steeper rareearth-element (REE) patterns and low U, Th, and high-fieldstrength elements (HFSE), indicating addition of a new melt component to the magma system. It is anticipated that increasing involvement of the new melt component will be evident as the current eruption proceeds.

Excess Weapons Plutonium Disposition: Plutonium Packaging, Storage and Transportation and Waste Treatment, Storage and Disposal Activities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jardine, L J; Borisov, G B

2004-07-21

A fifth annual Excess Weapons Plutonium Disposition meeting organized by Lawrence Livermore National Laboratory (LLNL) was held February 16-18, 2004, at the State Education Center (SEC), 4 Aerodromnya Drive, St. Petersburg, Russia. The meeting discussed Excess Weapons Plutonium Disposition topics for which LLNL has the US Technical Lead Organization responsibilities. The technical areas discussed included Radioactive Waste Treatment, Storage, and Disposal, Plutonium Oxide and Plutonium Metal Packaging, Storage and Transportation and Spent Fuel Packaging, Storage and Transportation. The meeting was conducted with a conference format using technical presentations of papers with simultaneous translation into English and Russian. There were 46more » Russian attendees from 14 different Russian organizations and six non-Russian attendees, four from the US and two from France. Forty technical presentations were made. The meeting agenda is given in Appendix B and the attendance list is in Appendix C.« less

Astronauts Grissom and Young in Gemini Mission Simulator

NASA Image and Video Library

1964-05-22

S64-25295 (March 1964) --- Astronauts Virgil I. (Gus) Grissom (right) and John W. Young, prime crew for the first manned Gemini mission (GT-3), are shown inside a Gemini mission simulator at McDonnell Aircraft Corp., St. Louis, MO. The simulator will provide Gemini astronauts and ground crews with realistic mission simulation during intensive training prior to actual launch.

Environmental Assessment for the Proposed Construction of a Gas Station, Car-Care Center, Shoppette and Class Six, and Taco John’s Restaurant at Keesler Air Force Base, Biloxi, Harrison County, Mississippi

DTIC Science & Technology

2003-01-01

Groundcover on base consists primarily of Bermuda grass ( Cynodon dactylon), centipede grass (Eremochloa ophiluroides), and St. Augustine grass...notification to allow adequate lime fori eview. COASTAL PROGRAM COMPLIANCE (Coastal ari • activities only) : ( ) The activity has been reviewed and

Cultural Resources Survey of Six Revetment and Levee Items Above New Orleans.

DTIC Science & Technology

1982-01-20

presently known in the vicinity of the study area, the Bayou Jasmine site in St. John the Baptist Parish. This site has a Poverty Point as well as later...artifact is a fragment of a clear green bottle with seam that is embossed with the words " FLAVOR GUARD BOTTLE REFILLING PROHIBITED." These glass remains

The Parent-Child Relationship Competencies: How Three Infant-Parent Psychotherapists Find Paths into Diverse Infant-Family Landscapes

ERIC Educational Resources Information Center

St. John, Maria Seymour

2016-01-01

This article weaves the stories of three practitioner-family relationships and describes how the Parent-Child Relationship Competencies (PCRCs; St. John, 2010) function as a map for assessment and treatment planning. The PCRCs are a set of culturally variable yet universal bi-directional (parent-to-child and child-to-parent) relational capacities…

75 FR 12544 - Change in Bank Control Notices; Acquisition of Shares of Bank or Bank Holding Companies

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-16

... East Byrd Street, Richmond, Virginia 23261-4528:> 1. Peden B. McLeod, Mary H. McLeod, John R. McLeod, all of Walterboro, South Carolina; Peden B. McLeod, Jr., Mt. Pleasant, South Carolina; Mary C. Benson... of Walterboro, South Carolina. B. Federal Reserve Bank of St. Louis (Glenda Wilson, Community Affairs...

Teaching with Purpose: An Interview with Thomas E. Ludwig

ERIC Educational Resources Information Center

Ludwig, Timothy D.; Ludwig, David J.

2010-01-01

Thomas E. Ludwig is the John Dirk Werkman Professor of Psychology at Hope College, where he joined the faculty in 1977 after receiving his PhD in development and aging from Washington University in St. Louis. His research focuses on developmental issues in cognitive neuropsychology. He is also the author or coauthor of more than a dozen sets of…

Strengthening Career and Technical Education and 21st Century Skills in Philadelphia. Executive Summary

ERIC Educational Resources Information Center

Philadelphia Youth Network, 2009

2009-01-01

In Spring 2007, the John S. and James L. Knight Foundation awarded funds to the Philadelphia Youth Network (PYN) to undertake an analysis of Career and Technical Education (CTE) in Philadelphia, and to make recommendations on how CTE and other forms of career-connected education could better align with high-wage/high-demand jobs in the regional…

Defense.gov Special Report: 2011 ESGR Employer Support Freedom Awards

Science.gov Websites

dating to 1919 when the American Legion was first established in St. Louis at the utility's headquarters fact, 3M's CEO and president personally requested to be the executive sponsor when MSN was founded. The when I returned." More Hide Story U.S. Army National Guard Command Sergeant Major John Gipe, in

Corps of Engineers Structural Engineering Conference Held in St. Johns County, Florida on 8-12 July 1991. Volume 2

DTIC Science & Technology

1992-12-01

problems. Leadership forums were conducted for chiefs of structural design from each office for both military and civil works areas. (Continued) 14...Photographs ....................................... 7 Maintaining Design Quality in the Corps of Engineers .................... II Expedited Design and...25 Portugues Dam Monolith Layout and Survey Control ...................... 33 Cofferdam Design Problems, Point Marion Lock

Development and Validation of an Assessment Instrument for Course Experience in a General Education Integrated Science Course

ERIC Educational Resources Information Center

Liu, Juhong Christie; St. John, Kristen; Courtier, Anna M. Bishop

2017-01-01

Identifying instruments and surveys to address geoscience education research (GER) questions is among the high-ranked needs in a 2016 survey of the GER community (St. John et al., 2016). The purpose of this study was to develop and validate a student-centered assessment instrument to measure course experience in a general education integrated…

The Impact of Learning about Technology via Action Research as a Professional Development Activity on Higher Education: A Case Study

ERIC Educational Resources Information Center

Premdas, Leisa

2017-01-01

The purpose of this mixed method study was to determine the perceived impact of learning about technology via action research as a professional development activity on faculty and students in higher education. Nine faculty members--also Teaching and Technology Fellows representing various disciplines at St. John's University--were selected based…

Educational and Nonprofit Institutions Receiving Prime Contract Awards for Research, Development, Test, and Evaluation. Fiscal Year 1987.

DTIC Science & Technology

1987-01-01

Haytiard California 49 CORNELL UNIVERSITY 11,196 * Long Beach Cilifornia 2,535 Ithaca New York 9, 62 Sacramento Califjrnia 39 Ithaca Collge New York... PHYSICAL SCIENCE LABPATORY 58 * NORTH DAKOTA ST UNIVER ALUMN4I 50 Las Cruces New Mexroc 58 Fargo N Dakota 50 PIERCE JOHN B FOUNDATION LAB 116 NORH TEXAS

St. John’s Wort for Major Depressive Disorder: A Systematic Review

DTIC Science & Technology

2015-01-01

1.66; 9 RCTs; I2 94%). The existing evidence is based on RCTs testing SJW as monotherapy; there is a lack of evidence for SJW given as adjunct therapy ... therapy to standard antidepressant treatment. We found no systematic difference between SJW extracts, but head-to- head trials are missing; LI of 160... Therapy ? ............................... 26   Monotherapy

Breaking down "Healthism": Barriers to Health and Fitness as Identified by Immigrant Youth in St. John's, NL, Canada

ERIC Educational Resources Information Center

Shea, Jennifer M.; Beausoleil, Natalie

2012-01-01

In this article, we challenge dominant health and fitness discourses which stress individual responsibility in the attainment of these statuses. We examine the results of an empirical study exploring how a group of 15 Canadian immigrant youth, aged 12-17, discursively construct notions of health and fitness. Qualitative data were collected through…

Supplement Analysis for the Transmission System Vegetation Management Program FEIS (DOE/EIS-0285/SA-56)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stratton, Elaine

2002-04-09

Vegetation Management for the following electric yards located in the Ross District: Cape Horn, North Bonneville, Stevenson, Carson, Underwood, Troutdale, Cascade Locks, Acton Ross 345 kilovolts and J.D., Alcoa, Sifton, St. Johns, Ostrander, McLoughlin. BPA proposes to maintain a weed-free environment in the electrical substations located within the Olympia Region’s Ross District.

33 CFR 334.500 - St. Johns River, Atlantic Ocean, Sherman Creek; restricted areas and danger zone, Naval Station...

Code of Federal Regulations, 2014 CFR

2014-07-01

... north by Perimeter Road, and on the east by Mayport Road. (5) Danger zone. The danger zone shall... hours a day, seven days a week. Warning signs notifying individuals of the restricted area boundary and... will be in place 24 hours a day, seven days a week. Warning signs notifying individuals of the...

Experimental Research in TV Instruction. Proceedings of an International Conference (5th, St. John's, Newfoundland, June 28-30, 1982). Volume 5.

ERIC Educational Resources Information Center

Baggaley, Jon, Ed.; Janega, Patti, Ed.

An introduction briefly summarizes the four previous conferences in this series, identifies trends in topics addressed, and introduces the 16 presented papers in this collection. The papers are as follows: (1) "Formative Evaluation and the New Technologies" (Marjorie Cambre); (2) "Formative Evaluation of Sesame Street Using Eye…

Experimental Research in TV Instruction. Proceedings of an International Conference (4th, St. John's, Newfoundland, Canada, September 28-30, 1981). Volume 4.

ERIC Educational Resources Information Center

Baggaley, Jon, Ed.; Janega, Patti, Ed.

An introduction by Jon Baggaley provides background information on this international conference and its participants, and introduces 10 papers which were presented. The papers are as follows: (1) "Teaching Production Research and Design: The Interface of Theory and Practice" (James M. Linton); (2) "The Impact of Television on…

PVAST Propeller Vibration and Strength Analysis Program Version 7.3 User’s Manual

DTIC Science & Technology

2001-03-01

Copy No: ___ _ PVAST Propeller Vibration and Strength Analysis Program Version 7.3 User’s Manual Koko ,T S, Palmeter, M F, Chernuka, M.W. MARTEC...34St name, rruddle mittal If rruhtary, show rank, e g. Doe, Maj. John E.) Koko ,T.S., Palmeter, M.F., Chernuka, M.W. DATE OF PUBLICATION (month and

Impact of origin and biological source on chemical composition, anticholinesterase and antioxidant properties of some St. John's wort species (Hypericum spp., Hypericaceae) from the Central Balkans.

PubMed

Božin, Biljana; Kladar, Nebojša; Grujić, Nevena; Anačkov, Goran; Samojlik, Isidora; Gavarić, Neda; Conić, Branislava Srđenović

2013-09-25

The study shows the influence of the origin of plant material and biological source on the in vitro antioxidant (neutralization of DPPH and OH radical, nitric oxide, and inhibition of lipid peroxidation) and anticholinesterase activity of chemically characterized and quantified ethanol extracts of ten St. John's wort samples. The investigated samples were: five Hypericum perforatum species representatives collected at different localities, one commercial sample of Hyperici herba purchased at a local market and four Hypericum species autochtonous to the Balkan Peninsula (H. maculatum subsp. immaculatum, H. olympicum, H. richeri subsp. grisebachii and H. barbatum). All the examined extracts exhibited notable antioxidant potential, but in most of the cases indigenous Hypericum species expressed stronger effects compared to the original source of the drug, H. perforatum. The changes in the content of phenolic compounds, especially flavonoids, hyperforin and hypericin, related to the source of the drug affected the investigated activities. Since all of the investigated species have shown prominent inhibition of acetylcholinesterase in vitro activity, they could be further investigated as potential substances in preventing of Alzheimer's disease.

Elemental fingerprinting of Hypericum perforatum (St John's Wort) herb and preparations using ICP-OES and chemometrics.

PubMed

Owen, Jade D; Kirton, Stewart B; Evans, Sara J; Stair, Jacqueline L

2016-06-05

St. John's wort (SJW) (Hypericum perforatum) is a herbal remedy commonly used to treat mild depression. The elemental profiles of 54 samples (i.e., dry herbs, tablets and capsules) were evaluated by monitoring 25 elements using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). The major elemental constituents in the SJW samples were Ca (300-199,000μg/g), Mg (410-3,530μg/g), Al (4.4-900μg/g), Fe (1.154-760μg/g), Mn (2.4-261μg/g), Sr (0.88-83.6μg/g), and Zn (7-64μg/g). For the sixteen elements that could be reliably quantified, principal component analysis (PCA) was used to investigate underlying patterns in the data. PCA models identified 7 key elements (i.e., Ba, Ca, Cd, Mg, Mo, Ni and Y), which described 85% of the variance in the dataset in the first three principal components. The PCA approach resulted in a general delineation between the three different formulations and provides a basis for monitoring product quality in this manner. Copyright © 2016 Elsevier B.V. All rights reserved.

Comparative evolution of flower and fruit morphology

PubMed Central

Whitney, Kenneth D.

2009-01-01

Angiosperm diversification has resulted in a vast array of plant morphologies. Only recently has it been appreciated that diversification might have proceeded quite differently for the two key diagnostic structures of this clade, flowers and fruits. These structures are hypothesized to have experienced different selective pressures via their interactions with animals in dispersal mutualisms, resulting in a greater amount of morphological diversification in animal-pollinated flowers than in animal-dispersed fruits. I tested this idea using size and colour traits for the flowers and fruits of 472 species occurring in three floras (St John, Hawaii and the Great Plains). Phylogenetically controlled analyses of nearest-neighbour distances in multidimensional trait space matched the predicted pattern: in each of the three floras, flowers were more divergent from one another than were fruits. In addition, the spacing of species clusters differed for flowers versus fruits in the flora of St John, with clusters in flower space more divergent than those in fruit space. The results are consistent with the idea that a major driver of angiosperm diversification has been stronger selection for divergent floral morphology than for divergent fruit morphology, although genetic, physiological and ecological constraints may also play a role. PMID:19474045

The Sargassum Frogfish (Histrio histrio Linnaeus) observed in mangroves in St. John, US Virgin Islands

USGS Publications Warehouse

Rogers, C.S.; Pietsch, T.W.; Randall, J.E.; Arnold, R.J.

2010-01-01

The Sargassum Frogfish (Histrio histrio), the only pelagic member of the frogfish family Antennariidae, is considered an obligate associate of floating mats of the brown algae Sargassum natans and S. fluitans (Adams 1960; Dooley 1972; Pietsch and Grobecker 1987). Between February and April 2010, 20 of these fish were observed in three mangrove-fringed bays in Virgin Islands Coral Reef National Monument, St. John, US Virgin Islands. All of them were clinging to clumps of the red alga Acanthophora spicifera growing on the submerged prop roots of red mangrove trees (Rhizophora mangle) distributed along an estimated total of 2,160 mof shoreline (Fig. 1). All of the fish were at a depth of less than 0.5 meters. Two individuals were seen on one prop root, but the other 18 were solitary. Their estimated standard lengths ranged from about 20 to 100 mm. Littler and Littler (2000, p. 295) published a photograph of one individual in blades of the green alga Ulva lactuca growing on a prop root in Belize. This is the first report of the Sargassum Frogfish living in association with attached algae.

Hyperforin, a bio-active compound of St. John's Wort, is a new inhibitor of angiogenesis targeting several key steps of the process.

PubMed

Martínez-Poveda, Beatriz; Quesada, Ana R; Medina, Miguel Angel

2005-12-10

Hyperforin, a phloroglucinol derivative found in St. John's wort related mainly to its antidepressant effects, has been reported recently to induce apoptosis in tumour cells and to inhibit cancer invasion and metastasis. We show that hyperforin inhibits angiogenesis in vitro in bovine aortic endothelial cells and in vivo in the chorioallantoic membrane assay. In a variety of experimental systems representing the sequential events of the angiogenic process, hyperforin treatment of endothelial cells resulted in strong inhibitory effects. Hyperforin inhibited the growth of endothelial cells in culture. Capillary tube formation on Matrigel was abrogated completely by addition of hypeforin at the low micromolar range. Hyperforin also exhibited a clear inhibitory effect on the invasive capabilities of endothelial cells. Zymographic assays showed that hyperforin treatment produced a complete inhibition of urokinase and a remarkable inhibition of matrix metalloproteinase 2. Our data indicates that hyperforin is a compound that interferes with key events in angiogenesis, confirming the recent and growing evidence about a potential role of this compound in cancer and metastasis inhibition and making it a promising drug for further evaluation in the treatment of angiogenesis-related pathologies. Copyright 2005 Wiley-Liss, Inc

Hyperforin modulates dendritic spine morphology in hippocampal pyramidal neurons by activating Ca(2+) -permeable TRPC6 channels.

PubMed

Leuner, Kristina; Li, Wei; Amaral, Michelle D; Rudolph, Stephanie; Calfa, Gaston; Schuwald, Anita M; Harteneck, Christian; Inoue, Takafumi; Pozzo-Miller, Lucas

2013-01-01

The standardized extract of the St. John's wort plant (Hypericum perforatum) is commonly used to treat mild to moderate depression. Its active constituent is hyperforin, a phloroglucinol derivative that reduces the reuptake of serotonin and norepinephrine by increasing intracellular Na(+) concentration through the activation of nonselective cationic TRPC6 channels. TRPC6 channels are also Ca(2+) -permeable, resulting in intracellular Ca(2+) elevations. Indeed, hyperforin activates TRPC6-mediated currents and Ca(2+) transients in rat PC12 cells, which induce their differentiation, mimicking the neurotrophic effect of nerve growth factor. Here, we show that hyperforin modulates dendritic spine morphology in CA1 and CA3 pyramidal neurons of hippocampal slice cultures through the activation of TRPC6 channels. Hyperforin also evoked intracellular Ca(2+) transients and depolarizing inward currents sensitive to the TRPC channel blocker La(3+) , thus resembling the actions of the neurotrophin brain-derived neurotrophic factor (BDNF) in hippocampal pyramidal neurons. These results suggest that the antidepressant actions of St. John's wort are mediated by a mechanism similar to that engaged by BDNF. Copyright © 2012 Wiley Periodicals, Inc.

The pregnane X receptor agonist St John's Wort has no effects on the pharmacokinetics and pharmacodynamics of repaglinide.

PubMed

Fan, Lan; Zhou, Gan; Guo, Dong; Liu, Ya-Li; Chen, Wang-Qing; Liu, Zhao-Qian; Tan, Zhi-Rong; Sheng, Deng; Zhou, Hong-Hao; Zhang, Wei

2011-09-01

St John's wort (SJW; Hypericum perforatum) has been one of the most commonly used herbal remedies for mood disorders. This study aimed to investigate the effect of SJW, a pregnane X receptor (PXR) agonist, on the pharmacokinetics and pharmacodynamics of repaglinide, a widely consumed glucose-lowering drug. In a two-phase, randomized, crossover study with a 4-week washout period between phases, 15 healthy subjects with specific solute carrier organic anion transporter family member 1B1 (SLCO1B1) genotypes were given pretreatment with SJW 325 mg or placebo three times daily for 14 days, and a single dose of repaglinide 1 mg was administered followed by 75 g glucose at 15 minutes after repaglinide administration. In all subjects, SJW had no effect on the total area under the plasma concentration-time curve from time zero to infinity (AUC(∞)), the peak plasma concentration (C(max)) or the elimination half-life (t(½)) of repaglinide. In addition, SJW had no significant effect on the blood glucose-lowering and insulin-elevating effects of repaglinide. Consumption of SJW for 14 days had no clinically significant effect on the pharmacokinetics and pharmacodynamics of repaglinide.

Herb-drug interactions.

PubMed

Fugh-Berman, A

2000-01-08

Concurrent use of herbs may mimic, magnify, or oppose the effect of drugs. Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or danshen (Salvia miltiorrhiza); mild serotonin syndrome in patients who mix St John's wort (Hypericum perforatum) with serotonin-reuptake inhibitors; decreased bioavailability of digoxin, theophylline, cyclosporin, and phenprocoumon when these drugs are combined with St John's wort; induction of mania in depressed patients who mix antidepressants and Panax ginseng; exacerbation of extrapyramidal effects with neuroleptic drugs and betel nut (Areca catechu); increased risk of hypertension when tricyclic antidepressants are combined with yohimbine (Pausinystalia yohimbe); potentiation of oral and topical corticosteroids by liquorice (Glycyrrhiza glabra); decreased blood concentrations of prednisolone when taken with the Chinese herbal product xaio chai hu tang (sho-salko-to); and decreased concentrations of phenytoin when combined with the Ayurvedic syrup shankhapushpi. Anthranoid-containing plants (including senna [Cassia senna] and cascara [Rhamnus purshiana]) and soluble fibres (including guar gum and psyllium) can decrease the absorption of drugs. Many reports of herb-drug interactions are sketchy and lack laboratory analysis of suspect preparations. Health-care practitioners should caution patients against mixing herbs and pharmaceutical drugs.

St. John's Wort seed and feverfew flower extracts relieve painful diabetic neuropathy in a rat model of diabetes.

PubMed

Galeotti, Nicoletta; Maidecchi, Anna; Mattoli, Luisa; Burico, Michela; Ghelardini, Carla

2014-01-01

Painful diabetic peripheral neuropathy (DPN) is a common complication of diabetes and the few approved therapies for the management of pain have limited efficacy and side effects. With the aim to explore and develop new pharmacological treatments, we investigated the antihyperalgesic properties of St. John's Wort (SJW) and feverfew in streptozotocin (STZ)-diabetic rats. Acute administration of a SJW seed extract reversed mechanical hyperalgesia with a prolonged effect. A SJW extract obtained from the aerial portion of the plant and a feverfew flower extract partially relieved neuropathic pain whereas a feverfew leaf extract was ineffective. The antihyperalgesic efficacy of these herbal drugs was comparable to that of clinically used antihyperalgesic drugs (carbamazepine, lamotrigine, l-acetyl-levocarnitine). Further examinations of SJW and feverfew composition revealed that hyperforin and hypericin might be responsible for the antihyperalgesic properties of SJW whereas the efficacy of feverfew seems to be related to the presence of parthenolide. Rats undergoing treatment with SJW and feverfew did not show any behavioral side effect or sign of altered locomotor activity. Our results suggest that SJW and feverfew extracts may become new therapeutic perspectives for painful DPN. © 2013.

Zircon reveals protracted magma storage and recycling beneath Mount St. Helens

USGS Publications Warehouse

Claiborne, L.L.; Miller, C.F.; Flanagan, D.M.; Clynne, M.A.; Wooden, J.L.

2010-01-01

Current data and models for Mount St. Helens volcano (Washington, United States) suggest relatively rapid transport from magma genesis to eruption, with no evidence for protracted storage or recycling of magmas. However, we show here that complex zircon age populations extending back hundreds of thousands of years from eruption age indicate that magmas regularly stall in the crust, cool and crystallize beneath the volcano, and are then rejuvenated and incorporated by hotter, young magmas on their way to the surface. Estimated dissolution times suggest that entrained zircon generally resided in rejuvenating magmas for no more than about a century. Zircon elemental compositions reflect the increasing influence of mafic input into the system through time, recording growth from hotter, less evolved magmas tens of thousands of years prior to the appearance of mafic magmas at the surface, or changes in whole-rock geochemistry and petrology, and providing a new, time-correlated record of this evolution independent of the eruption history. Zircon data thus reveal the history of the hidden, long-lived intrusive portion of the Mount St. Helens system, where melt and crystals are stored for as long as hundreds of thousands of years and interact with fresh influxes of magmas that traverse the intrusive reservoir before erupting. ?? 2010 Geological Society of America.

Performance tests of three types of air-sampling bags on organic solvent vapor retention.

PubMed

Fukui, Yoshinari; Kanemaru, Ai; Nagasawa, Yasuhiro; Kawakami, Takuya; Iwata, Toyoto; Murata, Katsuyuki; Ohashi, Fumiko; Ikeda, Masayuki

2013-01-01

Performance of two new air sampling bags [the transparent bag (TP bag) and the semi-transparent bag (ST bag)] was examined as possible surrogates for the traditional PVF bag (the Ref bag). Solvent vapor mixture of butyl acetate, chloroform, ethyl acetate, isopropyl alcohol and toluene at administrative control levels were introduced to each bag (n=5 for each of the three types), and the decay in the concentrations (by%) was followed by use of a gas auto-sampler - FID-GC system. A trend of time-dependent decay was noted for all types including the Ref bag. When the performance was compared, the TP bag was equal to or even better than the Ref bag. In contrast, the performance of the ST bag was comparable to that of the other two types of bags with regard to toluene and chloroform when the storage time was short, but poorer than others for the other three solvents throughout the test period. The TP bag may be a bag of choice when the storage time is extended (e.g., up to 48 h) although this bag is physically less robust and requires careful handling. The ST bag may be used when analysis will be completed within 24 h.

21st International Conference on DNA Computing and Molecular Programming: 8.1 Biochemistry

DTIC Science & Technology

include information storage and biological applications of DNA systems, biomolecular chemical reaction networks, applications of self -assembled DNA...nanostructures, tile self -assembly and computation, principles and models of self -assembly, and strand displacement and biomolecular circuits. The fund

VP Structure of Mount St. Helens, Washington, USA, imaged with local earthquake tomography

USGS Publications Warehouse

Waite, G.P.; Moran, S.C.

2009-01-01

We present a new P-wave velocity model for Mount St. Helens using local earthquake data recorded by the Pacific Northwest Seismograph Stations and Cascades Volcano Observatory since the 18 May 1980 eruption. These data were augmented with records from a dense array of 19 temporary stations deployed during the second half of 2005. Because the distribution of earthquakes in the study area is concentrated beneath the volcano and within two nearly linear trends, we used a graded inversion scheme to compute a coarse-grid model that focused on the regional structure, followed by a fine-grid inversion to improve spatial resolution directly beneath the volcanic edifice. The coarse-grid model results are largely consistent with earlier geophysical studies of the area; we find high-velocity anomalies NW and NE of the edifice that correspond with igneous intrusions and a prominent low-velocity zone NNW of the edifice that corresponds with the linear zone of high seismicity known as the St. Helens Seismic Zone. This low-velocity zone may continue past Mount St. Helens to the south at depths below 5??km. Directly beneath the edifice, the fine-grid model images a low-velocity zone between about 2 and 3.5??km below sea level that may correspond to a shallow magma storage zone. And although the model resolution is poor below about 6??km, we found low velocities that correspond with the aseismic zone between about 5.5 and 8??km that has previously been modeled as the location of a large magma storage volume. ?? 2009 Elsevier B.V.

Postharvest biology, quality and shelf-life of buckwheat microgreens

USDA-ARS?s Scientific Manuscript database

Buckwheat microgreens are rich in antioxidants and provitamins/vitamins, including flavonoids, carotenoids, and a-tocopherol. However, short shelf life has limited their commercial use. The purpose of this study was to optimize storage conditions to extend the shelf life of buckwheat microgreens. St...

Cryopreservation of medicinal plants: role of melatonin

USDA-ARS?s Scientific Manuscript database

Many useful plant species found in Canada are of conservation concern. In vitro storage and cryopreservation techniques guarantees safety of these species and have potential applications which may result in sustainable agriculture. Shoot tips of in vitro-grown plantlets of American elm, St John’s Wo...

Cellulose nanomaterials emulsion coatings for controlling physiological activity, modifying surface morphology, and enhancing storability of postharvest bananas (Musa acuminate).

PubMed

Deng, Zilong; Jung, Jooyeoun; Simonsen, John; Zhao, Yanyun

2017-10-01

Cellulose nanomaterials (CNs)-incorporated emulsion coatings with improved moisture barrier, wettability and surface adhesion onto fruit surfaces were developed for controlling postharvest physiological activity and enhancing storability of bananas during ambient storage. Cellulose nanofiber (CNF)-based emulsion coating (CNFC: 0.3% CNF/1% oleic acid/1% sucrose ester fatty acid (w/w wet base)) had low contact angle, high spread coefficient onto banana surfaces, and lower surface tension (ST, 25.4mN/m) than the critical ST (35.2mN/m) of banana peels, and exhibited good wettability onto banana surfaces. CNFC coating delayed the ethylene biosynthesis pathway and reduced ethylene and CO 2 production, thus delaying fruit ripening. As the result, CNFC coating minimized chlorophyll degradation, weight loss, and firmness of bananas while ensuring the properly fruit ripening during 10d of ambient storage. This study demonstrated the effectiveness of CNF based emulsion coatings for improving the storability of postharvest bananas. Copyright © 2017 Elsevier Ltd. All rights reserved.

Physical activity and screen-time of childhood haematopoietic stem cell transplant survivors.

PubMed

Bogg, Tina Ft; Shaw, Peter J; Cohn, Richard J; Wakefield, Claire E; Hardy, Louise L; Broderick, Carolyn; Naumann, Fiona

2015-10-01

Reduced bone mineral density, impaired cardiovascular fitness and increased risk of obesity are well-known late effects of haematopoietic stem cell transplantation (HSCT) in survivors of childhood cancer. These comorbidities can be mitigated through physical activity and limiting screen-time (ST). This study aims to increase the understanding of physical activity and ST behaviours for children following HSCT. Children were recruited from two oncology follow-up clinics and completed a questionnaire on their physical activity levels and screen-time. Children were classified as short (≤2 years) and long-term (>2 years) survivors. Fifty-eight children were eligible, of whom forty children of age 6-18 years (60% males) participated in the study. Less than half (47.5%) met the daily recommendations for physical activity and one-third met the ST recommendations. Late survivors reported higher daily physical activity and less ST than early survivors. Among late survivors, females reported higher daily physical activity and less ST than males. Our findings suggest that the majority of children following HSCT were not sufficiently active and had excessive screen-time; however, this was comparable to healthy populations. Appropriately designed physical activity and screen-time intervention programmes should be explored early following transplant for children undergoing HSCT. ©2015 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Molecular epidemiological characteristics of Salmonella enterica serovars Enteritidis, Typhimurium and Livingstone strains isolated in a Tunisian university hospital.

PubMed

Ktari, Sonia; Ksibi, Boutheina; Gharsallah, Houda; Mnif, Basma; Maalej, Sonda; Rhimi, Fouzia; Hammami, Adnene

2016-03-01

Enteritidis, Typhimurium and Livingstone are the main Salmonella enterica serovars recovered in Tunisia. Here, we aimed to assess the genetic diversity of fifty-seven Salmonella enterica strains from different sampling periods, origins and settings using pulsed-field gel electrophoresis (PFGE), multi-locus sequence typing (MLST) and multi-locus variable-number tandem repeat analysis (MLVA). Salmonella Enteritidis, isolated from human and food sources from two regions in Sfax in 2007, were grouped into one cluster using PFGE. However, using MLVA these strains were divided into two clusters. Salmonella Typhimurium strains, recovered in 2012 and represent sporadic cases of human clinical isolates, were included in one PFGE cluster. Nevertheless, the MLVA technique, divided Salmonella Typhimurium isolates into six clusters with diversity index reaching (DI = 0.757). For Salmonella Livingstone which was responsible of two nosocomial outbreaks during 2000-2003, the PFGE and MLVA methods showed that these strains were genetically closely related. Salmonella Enteritidis and Salmonella Livingstone populations showed a single ST lineage ST11 and ST543 respectively. For Salmonella Typhimurium, two MLST sequence types ST19 and ST328 were defined. Salmonella Enteritidis and Salmonella Typhimurium strains were clearly differentiated by MLVA which was not the case using PFGE. © 2015 APMIS. Published by John Wiley & Sons Ltd.

A Framework for Treatment Decision Making at Prostate Cancer Recurrence.

PubMed

Lange, Jane M; Trock, Bruce J; Gulati, Roman; Etzioni, Ruth

2017-11-01

Of the 50,000 men in the US who elect for radical prostatectomy for prostate cancer, 24% to 40% will have a prostate-specific antigen (PSA) recurrence (PSA-R) within 10 years. Deciding whether to administer salvage therapy (ST) at PSA-R presents challenges, as treatment reduces the risk of progression to clinical metastasis but incurs unnecessary side effects should the man die before metastasis. We have developed a new harm-benefit framework using a clinical cohort to inform shared decision making between patients and physicians at PSA-R. Records of 1,045 Johns Hopkins University Hospital patients diagnosed between 1984 and 2013 who had PSA-R following radical prostatectomy were analyzed using marginal structural models to estimate the baseline risk of metastasis and the effect of ST (radiation therapy with or without hormone therapy) while accounting for selection into ST on the basis of PSA growth. The estimated model predicts the harm-benefit tradeoffs of ST within patient subgroups. The benefit of ST is the absolute reduction in the risk of metastasis within 10 years; the harm is the frequency of cancers that would not have metastasized in the patient's lifetime in the absence of ST (overtreatment). The adjusted hazard ratio associated with ST was 0.41 (95% CI, 0.31 to 0.55). Providing ST to all men at PSA-R reduced the risk of metastasis from 43% to 23% but led to 31% of men being overtreated (harm/benefit = 31/(43-23) = 1.6). Providing ST to men with Gleason score >7 reduced the risk of metastasis from 67% to 39%, with 13% of men being overtreated (harm/benefit = 13/(67-39) = 0.5). A quantitative framework that evaluates primary harms and benefits of ST after PSA-R will facilitate informed decision making. Immediate ST may be more appropriate in patient subgroups at elevated risk of metastasis.

Frostbite of the liver: an unrecognized cause of primary non-function?

PubMed

Potanos, Kristina; Kim, Heung Bae

2014-02-01

Appropriate hypothermic packaging techniques are an essential part of organ procurement. We present a case in which deviation from standard packaging practice may have caused sub-zero storage temperatures during transport, resulting in a clinical picture resembling PNF. An 18-month-old male with alpha-1-antitrypsin deficiency underwent liver transplant from a size-matched pediatric donor. Upon arrival at the recipient hospital, ice crystals were noted in the UW solution. The transplant proceeded uneventfully with short ischemia times. Surprisingly, transaminases, INR, and total bilirubin were markedly elevated in the postoperative period but returned to near normal by discharge. Follow-up of over five yr has demonstrated normal liver function. Upon review, it was discovered that organ packaging during recovery included storage in the first bag with only 400 mL of UW solution, and pure ice in the second bag instead of slush. This suggests that the postoperative delayed graft function was related to sub-zero storage of the graft during transport. This is the first report of sub-zero cold injury, or frostbite, following inappropriate packaging of an otherwise healthy donor liver. The clinical picture closely resembled PNF, perhaps implicating this mechanism in other unexpected cases of graft non-function. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Technology and the Longer View. Proceedings of the Annual National Conference on Technology and Education (1st, Ft. Worth, Texas, April 19-20, 1984).

ERIC Educational Resources Information Center

Klier, Betje, Ed.; And Others

To address the challenges to education posed by the new information technologies, participants from 41 states--publishers, administrators, teachers, subject specialists, and leaders from the field of educational computing--gathered to share ideas and visions. This report of the conference proceedings includes introductory comments by John Roach of…

Thinking about Thinking. Proceedings of the Annual Meeting of the South Atlantic Philosophy of Education Society (31st, Baltimore, Maryland, October 10-11, 1986).

ERIC Educational Resources Information Center

Craver, Samuel M., Ed.

The following papers (with authors and respondents) were presented at the annual conference of the South Atlantic Philosophy of Education Society: (1) "Teaching Critical Thinking through the Disciplines: Content Versus Process" (John E. McPeck) Respondent--Kingsley Price; (2) "Philosophy for Children and the Critical Thinking Movement" (Robert J.…

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (81st, Baltimore, Maryland, August 5-8, 1998). Mass Communication and Society.

ERIC Educational Resources Information Center

Association for Education in Journalism and Mass Communication.

The Mass Communication and Society section of the Proceedings contains the following 19 papers: "Talk Radio as Forum and Companion: Listener Attitudes and Uses and Gratifications in Austin, Texas" (John Beatty); "'Willingness to Censor': Developing a Quantitative Measurement across Speech Categories and Types of Media"…