Sample records for streamlining

  1. Efficient seeding and defragmentation of curvature streamlines for colonic polyp detection

    NASA Astrophysics Data System (ADS)

    Zhao, Lingxiao; Botha, Charl P.; Truyen, Roel; Vos, Frans M.; Post, Frits H.

    2008-03-01

    Many computer aided diagnosis (CAD) schemes have been developed for colon cancer detection using Virtual Colonoscopy (VC). In earlier work, we developed an automatic polyp detection method integrating flow visualization techniques, that forms part of the CAD functionality of an existing Virtual Colonoscopy pipeline. Curvature streamlines were used to characterize polyp surface shape. Features derived from curvature streamlines correlated highly with true polyp detections. During testing with a large number of patient data sets, we found that the correlation between streamline features and true polyps could be affected by noise and our streamline generation technique. The seeding and spacing constraints and CT noise could lead to streamline fragmentation, which reduced the discriminating power of our streamline features. In this paper, we present two major improvements of our curvature streamline generation. First, we adapted our streamline seeding strategy to the local surface properties and made the streamline generation faster. It generates a significantly smaller number of seeds but still results in a comparable and suitable streamline distribution. Second, based on our observation that longer streamlines are better surface shape descriptors, we improved our streamline tracing algorithm to produce longer streamlines. Our improved techniques are more effcient and also guide the streamline geometry to correspond better to colonic surface shape. These two adaptations support a robust and high correlation between our streamline features and true positive detections and lead to better polyp detection results.

  2. Interactive Streamline Exploration and Manipulation Using Deformation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tong, Xin; Chen, Chun-Ming; Shen, Han-Wei

    2015-01-12

    Occlusion presents a major challenge in visualizing three-dimensional flow fields with streamlines. Displaying too many streamlines at once makes it difficult to locate interesting regions, but displaying too few streamlines risks missing important features. A more ideal streamline exploration model is to allow the viewer to freely move across the field that has been populated with interesting streamlines and pull away the streamlines that cause occlusion so that the viewer can inspect the hidden ones in detail. In this paper, we present a streamline deformation algorithm that supports such user-driven interaction with three-dimensional flow fields. We define a view-dependent focus+contextmore » technique that moves the streamlines occluding the focus area using a novel displacement model. To preserve the context surrounding the user-chosen focus area, we propose two shape models to define the transition zone for the surrounding streamlines, and the displacement of the contextual streamlines is solved interactively with a goal of preserving their shapes as much as possible. Based on our deformation model, we design an interactive streamline exploration tool using a lens metaphor. Our system runs interactively so that users can move their focus and examine the flow field freely.« less

  3. Hierarchical streamline bundles.

    PubMed

    Yu, Hongfeng; Wang, Chaoli; Shene, Ching-Kuang; Chen, Jacqueline H

    2012-08-01

    Effective 3D streamline placement and visualization play an essential role in many science and engineering disciplines. The main challenge for effective streamline visualization lies in seed placement, i.e., where to drop seeds and how many seeds should be placed. Seeding too many or too few streamlines may not reveal flow features and patterns either because it easily leads to visual clutter in rendering or it conveys little information about the flow field. Not only does the number of streamlines placed matter, their spatial relationships also play a key role in understanding the flow field. Therefore, effective flow visualization requires the streamlines to be placed in the right place and in the right amount. This paper introduces hierarchical streamline bundles, a novel approach to simplifying and visualizing 3D flow fields defined on regular grids. By placing seeds and generating streamlines according to flow saliency, we produce a set of streamlines that captures important flow features near critical points without enforcing the dense seeding condition. We group spatially neighboring and geometrically similar streamlines to construct a hierarchy from which we extract streamline bundles at different levels of detail. Streamline bundles highlight multiscale flow features and patterns through clustered yet not cluttered display. This selective visualization strategy effectively reduces visual clutter while accentuating visual foci, and therefore is able to convey the desired insight into the flow data.

  4. 3D aquifer characterization using stochastic streamline calibration

    NASA Astrophysics Data System (ADS)

    Jang, Minchul

    2007-03-01

    In this study, a new inverse approach, stochastic streamline calibration is proposed. Using both a streamline concept and a stochastic technique, stochastic streamline calibration optimizes an identified field to fit in given observation data in a exceptionally fast and stable fashion. In the stochastic streamline calibration, streamlines are adopted as basic elements not only for describing fluid flow but also for identifying the permeability distribution. Based on the streamline-based inversion by Agarwal et al. [Agarwal B, Blunt MJ. Streamline-based method with full-physics forward simulation for history matching performance data of a North sea field. SPE J 2003;8(2):171-80], Wang and Kovscek [Wang Y, Kovscek AR. Streamline approach for history matching production data. SPE J 2000;5(4):353-62], permeability is modified rather along streamlines than at the individual gridblocks. Permeabilities in the gridblocks which a streamline passes are adjusted by being multiplied by some factor such that we can match flow and transport properties of the streamline. This enables the inverse process to achieve fast convergence. In addition, equipped with a stochastic module, the proposed technique supportively calibrates the identified field in a stochastic manner, while incorporating spatial information into the field. This prevents the inverse process from being stuck in local minima and helps search for a globally optimized solution. Simulation results indicate that stochastic streamline calibration identifies an unknown permeability exceptionally quickly. More notably, the identified permeability distribution reflected realistic geological features, which had not been achieved in the original work by Agarwal et al. with the limitations of the large modifications along streamlines for matching production data only. The constructed model by stochastic streamline calibration forecasted transport of plume which was similar to that of a reference model. By this, we can expect the proposed approach to be applied to the construction of an aquifer model and forecasting of the aquifer performances of interest.

  5. Clustered streamlined forms in Athabasca Valles, Mars: Evidence for sediment deposition during floodwater ponding

    USGS Publications Warehouse

    Burr, D.

    2005-01-01

    A unique clustering of layered streamlined forms in Athabasca Valles is hypothesized to reflect a significant hydraulic event. The forms, interpreted as sedimentary, are attributed to extensive sediment deposition during ponding and then streamlining of this sediment behind flow obstacles during ponded water outflow. These streamlined forms are analogous to those found in depositional basins and other loci of ponding in terrestrial catastrophic flood landscapes. These terrestrial streamlined forms can provide the best opportunity for reconstructing the history of the terrestrial flooding. Likewise, the streamlined forms in Athabasca Valles may provide the best opportunity to reconstruct the recent geologic history of this young Martian outflow channel. ?? 2005 Elsevier B.V. All rights reserved.

  6. Streamlines behind curved shock waves in axisymmetric flow fields

    NASA Astrophysics Data System (ADS)

    Filippi, A. A.; Skews, B. W.

    2018-07-01

    Streamlines behind axisymmetric curved shock waves were used to predict the internal surfaces that produced them. Axisymmetric ring wedge models with varying internal radii of curvature and leading-edge angles were used to produce numerical results. Said numerical simulations were validated using experimental shadowgraph results for a series of ring wedge test pieces. The streamlines behind curved shock waves for lower leading-edge angles are examined at Mach 3.4, whereas the highest leading-edge angle cases are explored at Mach 2.8 and 3.4. Numerical and theoretical streamlines are compared for the highest leading-edge angle cases at Mach 3.6. It was found that wall-bounding theoretical streamlines did not match the internal curved surface. This was due to extreme streamline curvature curving the streamlines when the shock angle approached the Mach angle at lower leading-edge angles. Increased Mach number and internal radius of curvature produced more reasonable results. Very good agreement was found between the theoretical and numerical streamlines at lower curvatures before the influence of the trailing edge expansion fan.

  7. Control software for two dimensional airfoil tests using a self-streamlining flexible walled transonic test section

    NASA Technical Reports Server (NTRS)

    Wolf, S. W. D.; Goodyer, M. J.

    1982-01-01

    Operation of the Transonic Self-Streamlining Wind Tunnel (TSWT) involved on-line data acquisition with automatic wall adjustment. A tunnel run consisted of streamlining the walls from known starting contours in iterative steps and acquiring model data. Each run performs what is described as a streamlining cycle. The associated software is presented.

  8. The impact of a streamlined funding application process on application time: two cross-sectional surveys of Australian researchers

    PubMed Central

    Barnett, Adrian G; Graves, Nicholas; Clarke, Philip; Herbert, Danielle

    2015-01-01

    Objective To examine if streamlining a medical research funding application process saved time for applicants. Design Cross-sectional surveys before and after the streamlining. Setting The National Health and Medical Research Council (NHMRC) of Australia. Participants Researchers who submitted one or more NHMRC Project Grant applications in 2012 or 2014. Main outcome measures Average researcher time spent preparing an application and the total time for all applications in working days. Results The average time per application increased from 34 working days before streamlining (95% CI 33 to 35) to 38 working days after streamlining (95% CI 37 to 39; mean difference 4 days, bootstrap p value <0.001). The estimated total time spent by all researchers on applications after streamlining was 614 working years, a 67-year increase from before streamlining. Conclusions Streamlined applications were shorter but took longer to prepare on average. Researchers may be allocating a fixed amount of time to preparing funding applications based on their expected return, or may be increasing their time in response to increased competition. Many potentially productive years of researcher time are still being lost to preparing failed applications. PMID:25596201

  9. Air Permitting Streamlining Techniques and Approaches for Greenhouse Gases, 2012

    EPA Pesticide Factsheets

    This report presents potential GHG permit streamlining options and observations developed by the Clean Air Act Advisory Committee (CAAAC): Permits, New Source Review and Toxics Subcommittee GHG Permit Streamlining Workgroup

  10. The impact of a streamlined funding application process on application time: two cross-sectional surveys of Australian researchers.

    PubMed

    Barnett, Adrian G; Graves, Nicholas; Clarke, Philip; Herbert, Danielle

    2015-01-16

    To examine if streamlining a medical research funding application process saved time for applicants. Cross-sectional surveys before and after the streamlining. The National Health and Medical Research Council (NHMRC) of Australia. Researchers who submitted one or more NHMRC Project Grant applications in 2012 or 2014. Average researcher time spent preparing an application and the total time for all applications in working days. The average time per application increased from 34 working days before streamlining (95% CI 33 to 35) to 38 working days after streamlining (95% CI 37 to 39; mean difference 4 days, bootstrap p value <0.001). The estimated total time spent by all researchers on applications after streamlining was 614 working years, a 67-year increase from before streamlining. Streamlined applications were shorter but took longer to prepare on average. Researchers may be allocating a fixed amount of time to preparing funding applications based on their expected return, or may be increasing their time in response to increased competition. Many potentially productive years of researcher time are still being lost to preparing failed applications. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  11. Streamline-curvature effect in three-dimensional boundary layers

    NASA Technical Reports Server (NTRS)

    Reed, Helen L.; Lin, Ray-Sing; Petraglia, Media M.

    1992-01-01

    The effect of including wall and streamline curvature terms in swept-wing boundary-layer stability calculations is studied. The linear disturbance equations are cast on a fixed, body-intrinsic, curvilinear coordinate system. Those nonparallel terms which contribute mainly to the streamline-curvature effect are retained in this formulation and approximated by their local finite-difference values. Convex-wall curvature has a stabilizing effect, while streamline curvature is destabilizing if the curvature exceeds a critical value.

  12. View-Dependent Streamline Deformation and Exploration

    PubMed Central

    Tong, Xin; Edwards, John; Chen, Chun-Ming; Shen, Han-Wei; Johnson, Chris R.; Wong, Pak Chung

    2016-01-01

    Occlusion presents a major challenge in visualizing 3D flow and tensor fields using streamlines. Displaying too many streamlines creates a dense visualization filled with occluded structures, but displaying too few streams risks losing important features. We propose a new streamline exploration approach by visually manipulating the cluttered streamlines by pulling visible layers apart and revealing the hidden structures underneath. This paper presents a customized view-dependent deformation algorithm and an interactive visualization tool to minimize visual clutter in 3D vector and tensor fields. The algorithm is able to maintain the overall integrity of the fields and expose previously hidden structures. Our system supports both mouse and direct-touch interactions to manipulate the viewing perspectives and visualize the streamlines in depth. By using a lens metaphor of different shapes to select the transition zone of the targeted area interactively, the users can move their focus and examine the vector or tensor field freely. PMID:26600061

  13. Animating streamlines with repeated asymmetric patterns for steady flow visualization

    NASA Astrophysics Data System (ADS)

    Yeh, Chih-Kuo; Liu, Zhanping; Lee, Tong-Yee

    2012-01-01

    Animation provides intuitive cueing for revealing essential spatial-temporal features of data in scientific visualization. This paper explores the design of Repeated Asymmetric Patterns (RAPs) in animating evenly-spaced color-mapped streamlines for dense accurate visualization of complex steady flows. We present a smooth cyclic variable-speed RAP animation model that performs velocity (magnitude) integral luminance transition on streamlines. This model is extended with inter-streamline synchronization in luminance varying along the tangential direction to emulate orthogonal advancing waves from a geometry-based flow representation, and then with evenly-spaced hue differing in the orthogonal direction to construct tangential flow streaks. To weave these two mutually dual sets of patterns, we propose an energy-decreasing strategy that adopts an iterative yet efficient procedure for determining the luminance phase and hue of each streamline in HSL color space. We also employ adaptive luminance interleaving in the direction perpendicular to the flow to increase the contrast between streamlines.

  14. View-Dependent Streamline Deformation and Exploration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tong, Xin; Edwards, John; Chen, Chun-Ming

    Occlusion presents a major challenge in visualizing 3D flow and tensor fields using streamlines. Displaying too many streamlines creates a dense visualization filled with occluded structures, but displaying too few streams risks losing important features. We propose a new streamline exploration approach by visually manipulating the cluttered streamlines by pulling visible layers apart and revealing the hidden structures underneath. This paper presents a customized view-dependent deformation algorithm and an interactive visualization tool to minimize visual cluttering for visualizing 3D vector and tensor fields. The algorithm is able to maintain the overall integrity of the fields and expose previously hidden structures.more » Our system supports both mouse and direct-touch interactions to manipulate the viewing perspectives and visualize the streamlines in depth. By using a lens metaphor of different shapes to select the transition zone of the targeted area interactively, the users can move their focus and examine the vector or tensor field freely.« less

  15. View-Dependent Streamline Deformation and Exploration.

    PubMed

    Tong, Xin; Edwards, John; Chen, Chun-Ming; Shen, Han-Wei; Johnson, Chris R; Wong, Pak Chung

    2016-07-01

    Occlusion presents a major challenge in visualizing 3D flow and tensor fields using streamlines. Displaying too many streamlines creates a dense visualization filled with occluded structures, but displaying too few streams risks losing important features. We propose a new streamline exploration approach by visually manipulating the cluttered streamlines by pulling visible layers apart and revealing the hidden structures underneath. This paper presents a customized view-dependent deformation algorithm and an interactive visualization tool to minimize visual clutter in 3D vector and tensor fields. The algorithm is able to maintain the overall integrity of the fields and expose previously hidden structures. Our system supports both mouse and direct-touch interactions to manipulate the viewing perspectives and visualize the streamlines in depth. By using a lens metaphor of different shapes to select the transition zone of the targeted area interactively, the users can move their focus and examine the vector or tensor field freely.

  16. User's guide and description of the streamline divergence computer program. [turbulent convective heat transfer

    NASA Technical Reports Server (NTRS)

    Sulyma, P. R.; Mcanally, J. V.

    1975-01-01

    The streamline divergence program was developed to demonstrate the capability to trace inviscid surface streamlines and to calculate outflow-corrected laminar and turbulent convective heating rates on surfaces subjected to exhaust plume impingement. The analytical techniques used in formulating this program are discussed. A brief description of the streamline divergence program is given along with a user's guide. The program input and output for a sample case are also presented.

  17. Aerofoil testing in a self-streamlining flexible walled wind tunnel. Ph.D. Thesis - Jul. 1987

    NASA Technical Reports Server (NTRS)

    Lewis, Mark Charles

    1988-01-01

    Two-dimensional self-streamlining flexible walled test sections eliminate, as far as experimentally possible, the top and bottom wall interference effects in transonic airfoil testing. The test section sidewalls are rigid, while the impervious top and bottom walls are flexible and contoured to streamline shapes by a system of jacks, without reference to the airfoil model. The concept of wall contouring to eliminate or minimize test section boundary interference in 2-D testing was first demonstrated by NPL in England during the early 40's. The transonic streamlining strategy proposed, developed and used by NPL has been compared with several modern strategies. The NPL strategy has proved to be surprisingly good at providing a wall interference-free test environment, giving model performance indistinguishable from that obtained using the modern strategies over a wide range of test conditions. In all previous investigations the achievement of wall streamlining in flexible walled test sections has been limited to test sections up to those resulting in the model's shock just extending to a streamlined wall. This work however, has also successfully demonstrated the feasibility of 2-D wall streamlining at test conditions where both model shocks have reached and penetrated through their respective flexible walls. Appropriate streamlining procedures have been established and are uncomplicated, enabling flexible walled test sections to cope easily with these high transonic flows.

  18. CASE STUDIES EXAMINING LCA STREAMLINING TECHNIQUES

    EPA Science Inventory

    Pressure is mounting for more streamlined Life Cycle Assessment (LCA) methods that allow for evaluations that are quick and simple, but accurate. As part of an overall research effort to develop and demonstrate streamlined LCA, the U.S. Environmental Protection Agency has funded ...

  19. Acquisition streamlining: A cultural change

    NASA Technical Reports Server (NTRS)

    Stewart, Jesse

    1992-01-01

    The topics are presented in viewgraph form and include the following: the defense systems management college, educational philosophy, the defense acquisition environment, streamlining initiatives, organizational streamlining types, defense law review, law review purpose, law review objectives, the Public Law Pilot Program, and cultural change.

  20. 77 FR 14700 - Streamlining Inherited Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ... contains notices to the public of #0;the proposed issuance of rules and regulations. The purpose of these... X [Docket No. CFPB-2011-0039] Streamlining Inherited Regulations AGENCY: Bureau of Consumer... the public for streamlining regulations it recently inherited from other Federal agencies (the...

  1. ACHP | News | Nationwide Programmatic Agreement Streamlines 106 Process for

    Science.gov Websites

    Publications Search skip specific nav links Home arrow News arrow Nationwide Programmatic Agreement Streamlines 106 Process for NPS Nationwide Programmatic Agreement Streamlines 106 Process for NPS Pursuant to Service (NPS) on November 14, 2008, executed a nationwide Programmatic Agreement (PA) with the Advisory

  2. Enhanced Performance of Streamline-Traced External-Compression Supersonic Inlets

    NASA Technical Reports Server (NTRS)

    Slater, John W.

    2015-01-01

    A computational design study was conducted to enhance the aerodynamic performance of streamline-traced, external-compression inlets for Mach 1.6. The current study explored a new parent flowfield for the streamline tracing and several variations of inlet design factors, including the axial displacement and angle of the subsonic cowl lip, the vertical placement of the engine axis, and the use of porous bleed in the subsonic diffuser. The performance was enhanced over that of an earlier streamline-traced inlet such as to increase the total pressure recovery and reduce total pressure distortion

  3. Streamlining genomes: toward the generation of simplified and stabilized microbial systems.

    PubMed

    Leprince, Audrey; van Passel, Mark W J; dos Santos, Vitor A P Martins

    2012-10-01

    At the junction between systems and synthetic biology, genome streamlining provides a solid foundation both for increased understanding of cellular circuitry, and for the tailoring of microbial chassis towards innovative biotechnological applications. Iterative genomic deletions (targeted and random) helps to generate simplified, stabilized and predictable genomes, whereas multiplexing genome engineering reveals a broad functional genetic diversity. The decrease in oligo and gene synthesis costs promises effective combinatorial tools for the generation of chassis based on streamlined and tractable genomes. Here we review recent progresses in streamlining genomes through recombineering techniques aiming to generate insights into cellular mechanisms and responses towards the design and assembly of streamlined genome chassis together with new cellular modules in diverse biotechnological applications. Copyright © 2012 Elsevier Ltd. All rights reserved.

  4. Enhanced Performance of Streamline-Traced External-Compression Supersonic Inlets

    NASA Technical Reports Server (NTRS)

    Slater, John W.

    2015-01-01

    A computational design study was conducted to enhance the aerodynamic performance of streamline-traced, external-compression inlets for Mach 1.6. Compared to traditional external-compression, two-dimensional and axisymmetric inlets, streamline-traced inlets promise reduced cowl wave drag and sonic boom, but at the expense of reduced total pressure recovery and increased total pressure distortion. The current study explored a new parent flowfield for the streamline tracing and several variations of inlet design factors, including the axial displacement and angle of the subsonic cowl lip, the vertical placement of the engine axis, and the use of porous bleed in the subsonic diffuser. The performance was enhanced over that of an earlier streamline-traced inlet such as to increase the total pressure recovery and reduce total pressure distortion.

  5. Self streamlining wind tunnel: Low speed testing and transonic test section design

    NASA Technical Reports Server (NTRS)

    Wolf, S. W. D.; Goodyer, M. J.

    1977-01-01

    Comprehensive aerodynamic data on an airfoil section were obtained through a wide range of angles of attack, both stalled and unstalled. Data were gathered using a self streamlining wind tunnel and were compared to results obtained on the same section in a conventional wind tunnel. The reduction of wall interference through streamline was demonstrated.

  6. Novel diffusion tensor imaging technique reveals developmental streamline volume changes in the corticospinal tract associated with leg motor control

    PubMed Central

    Kamson, David O.; Juhász, Csaba; Chugani, Harry T.; Jeong, Jeong-Won

    2014-01-01

    Background Diffusion tensor imaging (DTI) has expanded our knowledge of corticospinal tract (CST) anatomy and development. However, previous developmental DTI studies assessed the CST as a whole, overlooking potential differences in development of its components related to control of the upper and lower extremities. The present cross-sectional study investigated age-related changes, side and gender differences in streamline volume of the leg- and hand-related segments of the CST in children. Subjects and methods DTI data of 31 children (1–14years; mean age: 6±4years; 17 girls) with normal conventional MRI were analyzed. Leg- and hand-related CST streamline volumes were quantified separately, using a recently validated novel tractography approach. CST streamline volumes on both sides were compared between genders and correlated with age. Results Higher absolute streamline volumes were found in the left leg-related CST compared to the right (p=0.001) without a gender effect (p=0.4), whereas no differences were found in the absolute hand-related CST volumes (p>0.4). CST leg-related streamline volumes, normalized to hemispheric white matter volumes, declined with age in the right hemisphere only (R=−.51; p=0.004). Absolute leg-related CST streamline volumes showed similar, but slightly weaker correlations. Hand-related absolute or normalized CST streamline volumes showed no age-related variations on either side. Conclusion These results suggest differential development of CST segments controlling hand vs. leg movements. Asymmetric volume changes in the lower limb motor pathway may be secondary to gradually strengthening left hemispheric dominance and is consistent with previous data suggesting that footedness is a better predictor of hemispheric lateralization than handedness. PMID:25027193

  7. Novel diffusion tensor imaging technique reveals developmental streamline volume changes in the corticospinal tract associated with leg motor control.

    PubMed

    Kamson, David O; Juhász, Csaba; Chugani, Harry T; Jeong, Jeong-Won

    2015-04-01

    Diffusion tensor imaging (DTI) has expanded our knowledge of corticospinal tract (CST) anatomy and development. However, previous developmental DTI studies assessed the CST as a whole, overlooking potential differences in development of its components related to control of the upper and lower extremities. The present cross-sectional study investigated age-related changes, side and gender differences in streamline volume of the leg- and hand-related segments of the CST in children. DTI data of 31 children (1-14 years; mean age: 6±4 years; 17 girls) with normal conventional MRI were analyzed. Leg- and hand-related CST streamline volumes were quantified separately, using a recently validated novel tractography approach. CST streamline volumes on both sides were compared between genders and correlated with age. Higher absolute streamline volumes were found in the left leg-related CST compared to the right (p=0.001) without a gender effect (p=0.4), whereas no differences were found in the absolute hand-related CST volumes (p>0.4). CST leg-related streamline volumes, normalized to hemispheric white matter volumes, declined with age in the right hemisphere only (R=-.51; p=0.004). Absolute leg-related CST streamline volumes showed similar, but slightly weaker correlations. Hand-related absolute or normalized CST streamline volumes showed no age-related variations on either side. These results suggest differential development of CST segments controlling hand vs. leg movements. Asymmetric volume changes in the lower limb motor pathway may be secondary to gradually strengthening left hemispheric dominance and is consistent with previous data suggesting that footedness is a better predictor of hemispheric lateralization than handedness. Copyright © 2014 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

  8. Effectiveness of and obstacles to antibiotic streamlining to amoxicillin monotherapy in bacteremic pneumococcal pneumonia.

    PubMed

    Blot, Mathieu; Pivot, Diane; Bourredjem, Abderrahmane; Salmon-Rousseau, Arnaud; de Curraize, Claire; Croisier, Delphine; Chavanet, Pascal; Binquet, Christine; Piroth, Lionel

    2017-09-01

    Antibiotic streamlining is pivotal to reduce the emergence of resistant bacteria. However, whether streamlining is frequently performed and safe in difficult situations, such as bacteremic pneumococcal pneumonia (BPP), has still to be assessed. All adult patients admitted to Dijon Hospital (France) from 2005 to 2013 who had BPP without complications, and were alive on the third day were enrolled. Clinical, biological, radiological, microbiological and therapeutic data were recorded. A first analysis was conducted to assess factors associated with being on amoxicillin on the third day. A second analysis, adjusting for a propensity score, was performed to determine whether 30-day mortality was associated with streamlining to amoxicillin monotherapy. Of the 196 patients hospitalized for BPP, 161 were still alive on the third day and were included in the study. Treatment was streamlined to amoxicillin in 60 patients (37%). Factors associated with not streamlining were severe pneumonia (OR 3.11, 95%CI [1.23-7.87]) and a first-line antibiotic combination (OR 3.08, 95%CI [1.34-7.09]). By contrast, starting with amoxicillin monotherapy correlated inversely with the risk of subsequent treatment with antibiotics other than amoxicillin (OR 0.06, 95%CI [0.01-0.30]). The Cox model adjusted for the propensity-score analysis showed that streamlining to amoxicillin during BPP was not significantly associated with a higher risk of 30-day mortality (HR 0.38, 95%CI [0.08-1.87]). Streamlining to amoxicillin is insufficiently implemented during BPP. This strategy is safe and potentially associated with ecological and economic benefits; therefore, it should be further encouraged, particularly when antibiotic combinations are started for severe pneumonia. Copyright © 2017. Published by Elsevier B.V.

  9. On a modified streamline curvature method for the Euler equations

    NASA Technical Reports Server (NTRS)

    Cordova, Jeffrey Q.; Pearson, Carl E.

    1988-01-01

    A modification of the streamline curvature method leads to a quasilinear second-order partial differential equation for the streamline coordinate function. The existence of a stream function is not required. The method is applied to subsonic and supersonic nozzle flow, and to axially symmetric flow with swirl. For many situations, the associated numerical method is both fast and accurate.

  10. STREAMLINED LIFE CYCLE ASSESSMENT: A FINAL REPORT FROM THE SETAC-NORTH AMERICA STREAMLINED LCA WORKGROUP

    EPA Science Inventory

    The original goal of the Streamlined LCA workgroup was to define and document a process for a shortened form of LCA. At the time, because of the large amount of data needed to do a cradle-to-grave evaluation, it was believed that in addition to such a "full" LCA approach there w...

  11. Streamline coal slurry letdown valve

    DOEpatents

    Platt, Robert J.; Shadbolt, Edward A.

    1983-01-01

    A streamlined coal slurry letdown valve is featured which has a two-piece throat comprised of a seat and seat retainer. The two-piece design allows for easy assembly and disassembly of the valve. A novel cage holds the two-piece throat together during the high pressure letdown. The coal slurry letdown valve has long operating life as a result of its streamlined and erosion-resistance surfaces.

  12. Streamline coal slurry letdown valve

    DOEpatents

    Platt, R.J.; Shadbolt, E.A.

    1983-11-08

    A streamlined coal slurry letdown valve is featured which has a two-piece throat comprised of a seat and seat retainer. The two-piece design allows for easy assembly and disassembly of the valve. A novel cage holds the two-piece throat together during the high pressure letdown. The coal slurry letdown valve has long operating life as a result of its streamlined and erosion-resistance surfaces. 5 figs.

  13. The status of analytical preparation for 2-dimensional testing at high transonic speeds in the University of Southampton transonic self-streamlining wind tunnel

    NASA Technical Reports Server (NTRS)

    Lewis, M. C.

    1984-01-01

    Validation data from the Transonic Self-Streamlining Wind Tunnel has proved the feasibility of streamlining two dimensional flexible walls at low speeds and up to transonic speeds, the upper limit being the speed where the flexible walls are just supercritical. At this condition, breakdown of the wall setting strategy is evident in that convergence is neither as rapid nor as stable as for lower speeds, and wall streamlining criteria are not always completely satisfied. The only major step necessary to permit the extension of two dimensional testing into higher transonic speeds is the provision of a rapid algorithm to solve for mixed flow in the imagery flow fields. The status of two dimensional high transonic testing in the Transonic Self-Streamlining Wind Tunnel is outlined and, in particular, the progress of adapting an algorithm, which solves the Transonic Small Perturbation Equation, for predicting the imagery flow fields is detailed.

  14. Research on Streamlines and Aerodynamic Heating for Unstructured Grids on High-Speed Vehicles

    NASA Technical Reports Server (NTRS)

    DeJarnette, Fred R.; Hamilton, H. Harris (Technical Monitor)

    2001-01-01

    Engineering codes are needed which can calculate convective heating rates accurately and expeditiously on the surfaces of high-speed vehicles. One code which has proven to meet these needs is the Langley Approximate Three-Dimensional Convective Heating (LATCH) code. It uses the axisymmetric analogue in an integral boundary-layer method to calculate laminar and turbulent heating rates along inviscid surface streamlines. It requires the solution of the inviscid flow field to provide the surface properties needed to calculate the streamlines and streamline metrics. The LATCH code has been used with inviscid codes which calculated the flow field on structured grids, Several more recent inviscid codes calculate flow field properties on unstructured grids. The present research develops a method to calculate inviscid surface streamlines, the streamline metrics, and heating rates using the properties calculated from inviscid flow fields on unstructured grids. Mr. Chris Riley, prior to his departure from NASA LaRC, developed a preliminary code in the C language, called "UNLATCH", to accomplish these goals. No publication was made on his research. The present research extends and improves on the code developed by Riley. Particular attention is devoted to the stagnation region, and the method is intended for programming in the FORTRAN 90 language.

  15. Implications of streamlining theory for microbial ecology

    PubMed Central

    Giovannoni, Stephen J; Cameron Thrash, J; Temperton, Ben

    2014-01-01

    Whether a small cell, a small genome or a minimal set of chemical reactions with self-replicating properties, simplicity is beguiling. As Leonardo da Vinci reportedly said, ‘simplicity is the ultimate sophistication'. Two diverging views of simplicity have emerged in accounts of symbiotic and commensal bacteria and cosmopolitan free-living bacteria with small genomes. The small genomes of obligate insect endosymbionts have been attributed to genetic drift caused by small effective population sizes (Ne). In contrast, streamlining theory attributes small cells and genomes to selection for efficient use of nutrients in populations where Ne is large and nutrients limit growth. Regardless of the cause of genome reduction, lost coding potential eventually dictates loss of function. Consequences of reductive evolution in streamlined organisms include atypical patterns of prototrophy and the absence of common regulatory systems, which have been linked to difficulty in culturing these cells. Recent evidence from metagenomics suggests that streamlining is commonplace, may broadly explain the phenomenon of the uncultured microbial majority, and might also explain the highly interdependent (connected) behavior of many microbial ecosystems. Streamlining theory is belied by the observation that many successful bacteria are large cells with complex genomes. To fully appreciate streamlining, we must look to the life histories and adaptive strategies of cells, which impose minimum requirements for complexity that vary with niche. PMID:24739623

  16. Exploring the Biotic Pump Hypothesis along Non-linear Transects in Tropical South America

    NASA Astrophysics Data System (ADS)

    Molina, R.; Bettin, D. M.; Salazar, J. F.; Villegas, J. C.

    2014-12-01

    Forests might actively transport atmospheric moisture from the oceans, according to the biotic pump of atmospheric moisture (BiPAM) hypothesis. The BiPAM hypothesis appears to be supported by the fact that precipitation drops exponentially with distance from ocean along non-forested land transects, but not on their forested counterparts. Yet researchers have discussed the difficulty in defining proper transects for BiPAM studies. Previous studies calculate precipitation gradients either along linear transects maximizing distance to the ocean, or along polylines following specific atmospheric pathways (e.g., aerial rivers). In this study we analyzed precipitation gradients along curvilinear streamlines of wind in tropical South America. Wind streamlines were computed using long-term quarterly averages of meridional and zonal wind components from the ERA-Interim and NCEP/NCAR reanalyses. Total precipitation along streamlines was obtained from four data sources: TRMM, UDEL, ERA-Interim, and NCEP/NCAR. Precipitation on land versus distance from the ocean was analyzed along selected streamlines for each data source. As predicted by BiPAM, precipitation gradients did not decrease exponentially along streamlines in the vicinity of the Amazon forest, but dropped rapidly as distance from the forest increased. Remarkably, precipitation along streamlines in some areas outside the Amazon forest did not decrease exponentially either. This was possibly owing to convergence of moisture conveyed by low level jets (LLJs) in those areas (e.g., streamlines driven by the Caribbean and CHOCO jets on the Pacific coast of Colombia). Significantly, BiPAM held true even along long transects displaying strong sinuosity. In fact, the general conclusions of previous studies remain valid. Yet effects of LLJs on precipitation gradients need to be thoroughly considered in future BiPAM studies.

  17. Creating customer value by streamlining business processes.

    PubMed

    Vantrappen, H

    1992-02-01

    Much of the strategic preoccupation of senior managers in the 1990s is focusing on the creation of customer value. Companies are seeking competitive advantage by streamlining the three processes through which they interact with their customers: product creation, order handling and service assurance. 'Micro-strategy' is a term which has been coined for the trade-offs and decisions on where and how to streamline these three processes. The article discusses micro-strategies applied by successful companies.

  18. The impact of groundwater velocity fields on streamlines in an aquifer system with a discontinuous aquitard (Inner Mongolia, China)

    NASA Astrophysics Data System (ADS)

    Wu, Qiang; Zhao, Yingwang; Xu, Hua

    2018-04-01

    Many numerical methods that simulate groundwater flow, particularly the continuous Galerkin finite element method, do not produce velocity information directly. Many algorithms have been proposed to improve the accuracy of velocity fields computed from hydraulic potentials. The differences in the streamlines generated from velocity fields obtained using different algorithms are presented in this report. The superconvergence method employed by FEFLOW, a popular commercial code, and some dual-mesh methods proposed in recent years are selected for comparison. The applications to depict hydrogeologic conditions using streamlines are used, and errors in streamlines are shown to lead to notable errors in boundary conditions, the locations of material interfaces, fluxes and conductivities. Furthermore, the effects of the procedures used in these two types of methods, including velocity integration and local conservation, are analyzed. The method of interpolating velocities across edges using fluxes is shown to be able to eliminate errors associated with refraction points that are not located along material interfaces and streamline ends at no-flow boundaries. Local conservation is shown to be a crucial property of velocity fields and can result in more accurate streamline densities. A case study involving both three-dimensional and two-dimensional cross-sectional models of a coal mine in Inner Mongolia, China, are used to support the conclusions presented.

  19. Impact assessment: Eroding benefits through streamlining?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bond, Alan, E-mail: alan.bond@uea.ac.uk; School of Geo and Spatial Sciences, North-West University; Pope, Jenny, E-mail: jenny@integral-sustainability.net

    This paper argues that Governments have sought to streamline impact assessment in recent years (defined as the last five years) to counter concerns over the costs and potential for delays to economic development. We hypothesise that this has had some adverse consequences on the benefits that subsequently accrue from the assessments. This hypothesis is tested using a framework developed from arguments for the benefits brought by Environmental Impact Assessment made in 1982 in the face of the UK Government opposition to its implementation in a time of economic recession. The particular benefits investigated are ‘consistency and fairness’, ‘early warning’, ‘environmentmore » and development’, and ‘public involvement’. Canada, South Africa, the United Kingdom and Western Australia are the jurisdictions tested using this framework. The conclusions indicate that significant streamlining has been undertaken which has had direct adverse effects on some of the benefits that impact assessment should deliver, particularly in Canada and the UK. The research has not examined whether streamlining has had implications for the effectiveness of impact assessment, but the causal link between streamlining and benefits does sound warning bells that merit further investigation. -- Highlights: • Investigation of the extent to which government has streamlined IA. • Evaluation framework was developed based on benefits of impact assessment. • Canada, South Africa, the United Kingdom, and Western Australia were examined. • Trajectory in last five years is attrition of benefits of impact assessment.« less

  20. Fast Automatic Segmentation of White Matter Streamlines Based on a Multi-Subject Bundle Atlas.

    PubMed

    Labra, Nicole; Guevara, Pamela; Duclap, Delphine; Houenou, Josselin; Poupon, Cyril; Mangin, Jean-François; Figueroa, Miguel

    2017-01-01

    This paper presents an algorithm for fast segmentation of white matter bundles from massive dMRI tractography datasets using a multisubject atlas. We use a distance metric to compare streamlines in a subject dataset to labeled centroids in the atlas, and label them using a per-bundle configurable threshold. In order to reduce segmentation time, the algorithm first preprocesses the data using a simplified distance metric to rapidly discard candidate streamlines in multiple stages, while guaranteeing that no false negatives are produced. The smaller set of remaining streamlines is then segmented using the original metric, thus eliminating any false positives from the preprocessing stage. As a result, a single-thread implementation of the algorithm can segment a dataset of almost 9 million streamlines in less than 6 minutes. Moreover, parallel versions of our algorithm for multicore processors and graphics processing units further reduce the segmentation time to less than 22 seconds and to 5 seconds, respectively. This performance enables the use of the algorithm in truly interactive applications for visualization, analysis, and segmentation of large white matter tractography datasets.

  1. The erosion of streamlined islands, longitudinal grooves and scour marks: Implications to the origin of the Martian outflow channels

    NASA Technical Reports Server (NTRS)

    Komar, P. D.

    1984-01-01

    The diversity of proposed origins for large Martian outflow channels results from the differing interpretations given to the landforms associated with the outflow channels. In an attempt to help limit the possible mechanisms of channel erosion, detailed studies of three of the channel features were done; the streamlined islands, longitudinal grooves and scour marks. This examination involved a comparison of the martian streamlined islands with various streamlined landforms on Earth including those found in the Channel Scabland in large rivers, glacial drumlins, and desert yardangs. The comparisons included statistical analyses of the landform lengths versus widths and positions of maximum width, and an examination of the degree of shape agreement with the geometric lemniscate which was in turn demonstrated to correspond closely with true airfoil shapes. The analyses showed that the shapes of the martian islands correspond closely to the streamlined islands in rivers and the Channel Scabland land. Drumlins show a much smaller correlation. Erosional rock islands formed by glaciers are very much different in shape.

  2. Exploratory study of in-plane streamline curvature effects on a turbulent boundary layer at a Mach number of 3

    NASA Technical Reports Server (NTRS)

    Bogdonoff, Seymour M.

    1991-01-01

    This report on a program to study in-plane streamline curvature effects in a turbulent boundary layer at a Mach number of 3. The original proposal, for a 3-year program to explore in-plane streamline curvature effects on a supersonic turbulent boundary layer using three-dimensional pressure fields generated by fins and wall geometry, ended after one year. The purpose of these tests was to compare these streamline curvature effects to the more classical two-dimensional curvature generated by wall shape and imposed pressure gradients, previously considered primarily in a plane normal to the floor. The studies were carried out in the Mach number of 3, 8 x 8 inch High Reynolds Number Supersonic Tunnel. The usual surface visualization and mean wall static pressures were supplemented by the use of many small high frequency wall static pressure gauges (Kulites) to get some indication of the amplification of boundary layer disturbances by the in-plane streamline curvature caused by the three-dimensional pressure fields imposed on the boundary layer.

  3. The effects of streamline curvature and swirl on turbulent flows in curved ducts

    NASA Technical Reports Server (NTRS)

    Cheng, Chih-Hsiung; Farokhi, Saeed

    1990-01-01

    A technique for improving the numerical predictions of turbulent flows with the effect of streamline curvature is developed. Separated flows, the flow in a curved duct, and swirling flows are examples of flow fields where streamline curvature plays a dominant role. A comprehensive literature review on the effect of streamline curvature was conducted. New algebraic formulations for the eddy viscosity incorporating the kappa-epsilon turbulence model are proposed to account for various effects of streamline curvature. The loci of flow reversal of the separated flows over various backward-facing steps are employed to test the capability of the proposed turbulence model in capturing the effect of local curvature. The inclusion of the effect of longitudinal curvature in the proposed turbulence model is validated by predicting the distributions of the static pressure coefficients in an S-bend duct and in 180 degree turn-around ducts. The proposed turbulence model embedded with transverse curvature modification is substantiated by predicting the decay of the axial velocities in the confined swirling flows. The numerical predictions of different curvature effects by the proposed turbulence models are also reported.

  4. The design and operational development of self-streamlining 2-dimensional flexible walled test sections. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Wolf, S. W. D.

    1984-01-01

    Self streamlining two dimensional flexible walled test sections eliminate the uncertainties found in data from conventional test sections particularly at transonic speeds. The test section sidewalls are rigid, while the floor and ceiling are flexible and are positioned to streamline shapes by a system of jacks, without reference to the model. The walls are therefore self streamlining. Data are taken from the model when the walls are good streamlines such that the inevitable residual wall induced interference is acceptably small and correctable. Successful two dimensional validation testing at low speeds has led to the development of a new transonic flexible walled test section. Tunnel setting times are minimized by the development of a rapid wall setting strategy coupled with on line computer control of wall shapes using motorized jacks. Two dimensional validation testing using symmetric and cambered aerofoils in the Mach number range up to about 0.85 where the walls are just supercritical, shows good agreement with reference data using small height-chord ratios between 1.5 and unity.

  5. Impingement of Droplets in 90 deg Elbows with Potential Flow

    NASA Technical Reports Server (NTRS)

    Hacker, Paul T.; Brun, Rinaldo J.; Boyd, Bemrose

    1953-01-01

    Trajectories were determined for droplets in air flowing through 90 deg elbows especially designed for two-dimensional potential motion with low pressure losses. The elbows were established by selecting as walls of each elbow two streamlines of the flow field produced by a complex potential function that establishes a two-dimensional flow around a 90 deg bend. An unlimited number of elbows with slightly different shapes can be established by selecting different pairs of streamlines as walls. The elbows produced by the complex potential function selected are suitable for use in aircraft air-intake ducts. The droplet impingement data derived from the trajectories are presented along with equations in such a manner that the collection efficiency, the area, the rate, and the distribution of droplet impingement can be determined for any elbow defined by any pair of streamlines within a portion of the flow field established by the complex potential function. Coordinates for some typical streamlines of the flow field and velocity components for several points along these streamlines are presented in tabular form.

  6. Guessing right for the next war: streamlining, pooling, and right-timing force design decisions for an environment of uncertainty

    DTIC Science & Technology

    2017-05-25

    Guessing Right for the Next War: Streamlining, Pooling, and Right-Timing Force Design Decisions for an Environment of Uncertainty A...JUN 2016 – MAY 2017 4. TITLE AND SUBTITLE Guessing Right for the Next War: Streamlining, Pooling, and Right- Timing Force Design Decisions for an...committing to one force design solution to modern combat. The Army after World War II shied away from temporary organizational systems like these in

  7. Calculation of laminar heating rates on three-dimensional configurations using the axisymmetric analogue

    NASA Technical Reports Server (NTRS)

    Hamilton, H. H., II

    1980-01-01

    A theoretical method was developed for computing approximate laminar heating rates on three dimensional configurations at angle of attack. The method is based on the axisymmetric analogue which is used to reduce the three dimensional boundary layer equations along surface streamlines to an equivalent axisymmetric form by using the metric coefficient which describes streamline divergence (or convergence). The method was coupled with a three dimensional inviscid flow field program for computing surface streamline paths, metric coefficients, and boundary layer edge conditions.

  8. Streamlined Island

    NASA Image and Video Library

    2014-04-15

    This image from NASA 2001 Mars Odyssey spacecraft shows a streamlined island in a broad channel in Chryse Planitia. The channel is part of the outflow region of Lobo Vallis, a northern branch of Kasei Valles.

  9. White Matter Tract Segmentation as Multiple Linear Assignment Problems

    PubMed Central

    Sharmin, Nusrat; Olivetti, Emanuele; Avesani, Paolo

    2018-01-01

    Diffusion magnetic resonance imaging (dMRI) allows to reconstruct the main pathways of axons within the white matter of the brain as a set of polylines, called streamlines. The set of streamlines of the whole brain is called the tractogram. Organizing tractograms into anatomically meaningful structures, called tracts, is known as the tract segmentation problem, with important applications to neurosurgical planning and tractometry. Automatic tract segmentation techniques can be unsupervised or supervised. A common criticism of unsupervised methods, like clustering, is that there is no guarantee to obtain anatomically meaningful tracts. In this work, we focus on supervised tract segmentation, which is driven by prior knowledge from anatomical atlases or from examples, i.e., segmented tracts from different subjects. We present a supervised tract segmentation method that segments a given tract of interest in the tractogram of a new subject using multiple examples as prior information. Our proposed tract segmentation method is based on the idea of streamline correspondence i.e., on finding corresponding streamlines across different tractograms. In the literature, streamline correspondence has been addressed with the nearest neighbor (NN) strategy. Differently, here we formulate the problem of streamline correspondence as a linear assignment problem (LAP), which is a cornerstone of combinatorial optimization. With respect to the NN, the LAP introduces a constraint of one-to-one correspondence between streamlines, that forces the correspondences to follow the local anatomical differences between the example and the target tract, neglected by the NN. In the proposed solution, we combined the Jonker-Volgenant algorithm (LAPJV) for solving the LAP together with an efficient way of computing the nearest neighbors of a streamline, which massively reduces the total amount of computations needed to segment a tract. Moreover, we propose a ranking strategy to merge correspondences coming from different examples. We validate the proposed method on tractograms generated from the human connectome project (HCP) dataset and compare the segmentations with the NN method and the ROI-based method. The results show that LAP-based segmentation is vastly more accurate than ROI-based segmentation and substantially more accurate than the NN strategy. We provide a Free/OpenSource implementation of the proposed method. PMID:29467600

  10. White Matter Tract Segmentation as Multiple Linear Assignment Problems.

    PubMed

    Sharmin, Nusrat; Olivetti, Emanuele; Avesani, Paolo

    2017-01-01

    Diffusion magnetic resonance imaging (dMRI) allows to reconstruct the main pathways of axons within the white matter of the brain as a set of polylines, called streamlines. The set of streamlines of the whole brain is called the tractogram. Organizing tractograms into anatomically meaningful structures, called tracts, is known as the tract segmentation problem, with important applications to neurosurgical planning and tractometry. Automatic tract segmentation techniques can be unsupervised or supervised. A common criticism of unsupervised methods, like clustering, is that there is no guarantee to obtain anatomically meaningful tracts. In this work, we focus on supervised tract segmentation, which is driven by prior knowledge from anatomical atlases or from examples, i.e., segmented tracts from different subjects. We present a supervised tract segmentation method that segments a given tract of interest in the tractogram of a new subject using multiple examples as prior information. Our proposed tract segmentation method is based on the idea of streamline correspondence i.e., on finding corresponding streamlines across different tractograms. In the literature, streamline correspondence has been addressed with the nearest neighbor (NN) strategy. Differently, here we formulate the problem of streamline correspondence as a linear assignment problem (LAP), which is a cornerstone of combinatorial optimization. With respect to the NN, the LAP introduces a constraint of one-to-one correspondence between streamlines, that forces the correspondences to follow the local anatomical differences between the example and the target tract, neglected by the NN. In the proposed solution, we combined the Jonker-Volgenant algorithm (LAPJV) for solving the LAP together with an efficient way of computing the nearest neighbors of a streamline, which massively reduces the total amount of computations needed to segment a tract. Moreover, we propose a ranking strategy to merge correspondences coming from different examples. We validate the proposed method on tractograms generated from the human connectome project (HCP) dataset and compare the segmentations with the NN method and the ROI-based method. The results show that LAP-based segmentation is vastly more accurate than ROI-based segmentation and substantially more accurate than the NN strategy. We provide a Free/OpenSource implementation of the proposed method.

  11. Self streamlining wind tunnel: Further low speed testing and final design studies for the transonic facility

    NASA Technical Reports Server (NTRS)

    Wolf, S. W. D.

    1977-01-01

    Work has continued with the low speed self streamlining wind tunnel (SSWT) using the NACA 0012-64 airfoil in an effort to explain the discrepancies between the NASA Langley low turbulence pressure tunnel (LTPT) and SSWT results obtained with the airfoil stalled. Conventional wind tunnel corrections were applied to straight wall SSWT airfoil data, to illustrate the inadequacy of standard correction techniques in circumstances of high blockage. Also one SSWT test was re-run at different air speeds to investigate the effects of such changes on airfoil data and wall contours. Mechanical design analyses for the transonic self streamlining wind tunnel (TSWT) were completed by the application of theoretical airfoil flow field data to the elastic beam and streamline analysis. The control system for the transonic facility is outlined.

  12. Adapting large batteries of research measures for immigrants.

    PubMed

    Aroian, Karen J

    2013-06-01

    A four-step, streamlined process to adapt a large battery of measures for a study of mother-child adjustment in Arab Muslim immigrants and the lessons learned are described. The streamlined process includes adapting content, translation, pilot testing, and extensive psychometric evaluation but omits in-depth qualitative inquiry to identify the full content domain of the constructs of interest and cognitive interviews to assess how respondents interpret items. Lessons learned suggest that the streamlined process is not sufficient for certain measures, particularly when there is little published information about how the measure performs with different groups, the measure requires substantial item revision to achieve content equivalence, and the measure is both challenging to translate and has little to no redundancy. When these conditions are present, condition-specific procedures need to be added to the streamlined process.

  13. Alignment of Tractograms As Graph Matching.

    PubMed

    Olivetti, Emanuele; Sharmin, Nusrat; Avesani, Paolo

    2016-01-01

    The white matter pathways of the brain can be reconstructed as 3D polylines, called streamlines, through the analysis of diffusion magnetic resonance imaging (dMRI) data. The whole set of streamlines is called tractogram and represents the structural connectome of the brain. In multiple applications, like group-analysis, segmentation, or atlasing, tractograms of different subjects need to be aligned. Typically, this is done with registration methods, that transform the tractograms in order to increase their similarity. In contrast with transformation-based registration methods, in this work we propose the concept of tractogram correspondence, whose aim is to find which streamline of one tractogram corresponds to which streamline in another tractogram, i.e., a map from one tractogram to another. As a further contribution, we propose to use the relational information of each streamline, i.e., its distances from the other streamlines in its own tractogram, as the building block to define the optimal correspondence. We provide an operational procedure to find the optimal correspondence through a combinatorial optimization problem and we discuss its similarity to the graph matching problem. In this work, we propose to represent tractograms as graphs and we adopt a recent inexact sub-graph matching algorithm to approximate the solution of the tractogram correspondence problem. On tractograms generated from the Human Connectome Project dataset, we report experimental evidence that tractogram correspondence, implemented as graph matching, provides much better alignment than affine registration and comparable if not better results than non-linear registration of volumes.

  14. A novel drug management system in the Febuxostat versus Allopurinol Streamlined Trial: A description of a pharmacy system designed to supply medications directly to patients within a prospective multicenter randomised clinical trial.

    PubMed

    Rogers, Amy; Flynn, Robert Wv; McDonnell, Patrick; Mackenzie, Isla S; MacDonald, Thomas M

    2016-12-01

    Trials of investigational medicinal products are required to adhere to strict guidelines with regard to the handling and supply of medication. Information technology offers opportunities to approach clinical trial methodology in new ways. This report summarises a novel pharmacy system designed to supply trial medications directly to patients by post in the Febuxostat versus Allopurinol Streamlined Trial. A bespoke web-based software package was designed to facilitate the direct supply of trial medications to Febuxostat versus Allopurinol Streamlined Trial participants from a pharmacy based in the Medicines Monitoring Unit, University of Dundee. To date, 65,467 packs of medication have been dispensed using the system to 3978 patients. Up to 238 packs per day have been dispensed. The Medicines Monitoring Unit Febuxostat versus Allopurinol Streamlined Trial drug management system is an effective method of administering the complex drug supply requirements of a large-scale clinical trial with advantages over existing arrangements. A low rate of loss to follow-up in the Febuxostat versus Allopurinol Streamlined Trial may be attributable to the drug management system. © The Author(s) 2016.

  15. Using the Triad Approach to Streamline Brownfields Site Assessment and Cleanup

    EPA Pesticide Factsheets

    EPA's Brownfields Technology Support Center (BTSC) has prepared this document to provide an educational tool for site owners, project managers, and regulators to help streamline assessment and cleanup activities at brownfields sites.

  16. A streamline curvature method for design of supercritical and subcritical airfoils

    NASA Technical Reports Server (NTRS)

    Barger, R. L.; Brooks, C. W., Jr.

    1974-01-01

    An airfoil design procedure, applicable to both subcritical and supercritical airfoils, is described. The method is based on the streamline curvature velocity equation. Several examples illustrating this method are presented and discussed.

  17. Case studies in geographic information systems for environmental streamlining

    DOT National Transportation Integrated Search

    2012-05-31

    This 2012 summary report addresses the current use of geographic information systems (GIS) and related technologies by State Departments of Transportation (DOTs) for environmental streamlining and stewardship, particularly in relation to the National...

  18. On turbulent flows dominated by curvature effects

    NASA Technical Reports Server (NTRS)

    Cheng, G. C.; Farokhi, S.

    1992-01-01

    A technique for improving the numerical predictions of turbulent flows with the effect of streamline curvature is developed. Separated flows and the flow in a curved duct are examples of flowfields where streamline curvature plays a dominant role. New algebraic formulations for the eddy viscosity incorporating the k-epsilon turbulence model are proposed to account for various effects of streamline curvature. The loci of flow reversal of the separated flows over various backward-facing steps are employed to test the capability of the proposed turbulence model in capturing the effect of local curvature.

  19. An N-body Integrator for Planetary Rings

    NASA Astrophysics Data System (ADS)

    Hahn, Joseph M.

    2011-04-01

    A planetary ring that is disturbed by a satellite's resonant perturbation can respond in an organized way. When the resonance lies in the ring's interior, the ring responds via an m-armed spiral wave, while a ring whose edge is confined by the resonance exhibits an m-lobed scalloping along the ring-edge. The amplitude of these disturbances are sensitive to ring surface density and viscosity, so modelling these phenomena can provide estimates of the ring's properties. However a brute force attempt to simulate a ring's full azimuthal extent with an N-body code will likely fail because of the large number of particles needed to resolve the ring's behavior. Another impediment is the gravitational stirring that occurs among the simulated particles, which can wash out the ring's organized response. However it is possible to adapt an N-body integrator so that it can simulate a ring's collective response to resonant perturbations. The code developed here uses a few thousand massless particles to trace streamlines within the ring. Particles are close in a radial sense to these streamlines, which allows streamlines to be treated as straight wires of constant linear density. Consequently, gravity due to these streamline is a simple function of the particle's radial distance to all streamlines. And because particles are responding to smooth gravitating streamlines, rather than discrete particles, this method eliminates the stirring that ordinarily occurs in brute force N-body calculations. Note also that ring surface density is now a simple function of streamline separations, so effects due to ring pressure and viscosity are easily accounted for, too. A poster will describe this N-body method in greater detail. Simulations of spiral density waves and scalloped ring-edges are executed in typically ten minutes on a desktop PC, and results for Saturn's A and B rings will be presented at conference time.

  20. Vision and air flow combine to streamline flying honeybees

    PubMed Central

    Taylor, Gavin J.; Luu, Tien; Ball, David; Srinivasan, Mandyam V.

    2013-01-01

    Insects face the challenge of integrating multi-sensory information to control their flight. Here we study a ‘streamlining' response in honeybees, whereby honeybees raise their abdomen to reduce drag. We find that this response, which was recently reported to be mediated by optic flow, is also strongly modulated by the presence of air flow simulating a head wind. The Johnston's organs in the antennae were found to play a role in the measurement of the air speed that is used to control the streamlining response. The response to a combination of visual motion and wind is complex and can be explained by a model that incorporates a non-linear combination of the two stimuli. The use of visual and mechanosensory cues increases the strength of the streamlining response when the stimuli are present concurrently. We propose this multisensory integration will make the response more robust to transient disturbances in either modality. PMID:24019053

  1. Self streamlining wind tunnel: Further low speed testing and final design studies for the transonic facility

    NASA Technical Reports Server (NTRS)

    Wolf, S. W. D.

    1978-01-01

    Work was continued with the low speed self streamlining wind tunnel (SSWT) using the NACA 0012-64 airfoil in an effort to explain the discrepancies between the NASA Langley low turbulence pressure tunnel (LTPT) and SSWT results obtained with the airfoil stalled. Conventional wind tunnel corrections were applied to straight wall SSWT airfoil data, to illustrate the inadequacy of standard correction techniques in circumstances of high blockage. Also one SSWT test was re-run at different air speeds to investigate the effects of such changes (perhaps through changes in Reynold's number and freestream turbulence levels) on airfoil data and wall contours. Mechanical design analyses for the transonic self-streamlining wind tunnel (TSWT) were completed by the application of theoretical airfoil flow field data to the elastic beam and streamline analysis. The control system for the transonic facility, which will eventually allow on-line computer operation of the wind tunnel, was outlined.

  2. 77 FR 50691 - Request for Information (RFI): Guidance on Data Streamlining and Reducing Undue Reporting Burden...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    .... Attention: HIV Data Streamlining. FOR FURTHER INFORMATION CONTACT: Andrew D. Forsyth Ph.D. or Vera... of HIV/AIDS programs that vary in their specifications (e.g., numerators, denominators, time frames...

  3. GIS for environmental stewardship and streamlining: an overview of state DOT practices

    DOT National Transportation Integrated Search

    2005-01-31

    The Federal Highway Administration (FHWA) supports the adoption and development of Geographic Information System (GIS) technologies to promote environmental streamlining and stewardship (referred to as GIS4EST). While several States have already appl...

  4. Methods to expedite and streamline utility relocations for road projects.

    DOT National Transportation Integrated Search

    2014-12-01

    This report describes best practices and tools to streamline and expedite utility relocations when they : are required as part of road construction projects. As part of this effort, a research team from the : Kentucky Transportation Center (KTC) cond...

  5. West Virginia peer exchange : streamlining highway safety improvement program project delivery.

    DOT National Transportation Integrated Search

    2015-01-01

    The West Virginia Division of Highways (WV DOH) hosted a Peer Exchange to share information and experiences : for streamlining Highway Safety Improvement Program (HSIP) project delivery. The event was held September : 22 to 23, 2014 in Charleston, We...

  6. 48 CFR 252.211-7000 - Acquisition streamlining.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Acquisition streamlining. 252.211-7000 Section 252.211-7000 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text...

  7. Adaptive wall research with two- and three-dimensional models in low speed and transonic tunnels

    NASA Technical Reports Server (NTRS)

    Lewis, M. C.; Neal, G.; Goodyer, M. J.

    1988-01-01

    This paper summarises recent research at the University of Southampton into adaptive wall technology and outlines the direction of current efforts. The work is aimed at developing techniques for use in test sections where the top and bottom walls may be adjusted in single curvature. Wall streamlining eliminates, as far as experimentally possible, the top and bottom wall interference in low speed and transonic aerofoil testing. A streamlining technique has been developed for low speeds which allows the testing of swept wing panels in low interference environments. At higher speeds, a comparison of several two-dimensional transonic streamlining algorithms has been made and a technique for streamlining with a choked test section has also been developed. Three-dimensional work has mainly concentrated on tests of sidewall mounted half-wings and the development of the software packages required to assess interference and to adjust the flexible walls. It has been demonstrated that two-dimensional wall adaptation can significantly modify the level of wall interference around relatively large three-dimensional models. The residual interferences are small and are probably amenable to standard post-test correction methods. Tests on a calibrated wing-body model are planned in the near future to further validate the proposed streamlining technique.

  8. Iron Catalyst Chemistry in High Pressure Carbon Monoxide Nanotube Reactor

    NASA Technical Reports Server (NTRS)

    Scott, Carl D.; Povitsky, Alexander; Dateo, Christopher; Gokcen, Tahir; Smalley, Richard E.

    2001-01-01

    The high-pressure carbon monoxide (HiPco) technique for producing single wall carbon nanotubes (SWNT) is analyzed using a chemical reaction model coupled with properties calculated along streamlines. Streamline properties for mixing jets are calculated by the FLUENT code using the k-e turbulent model for pure carbon monixide. The HiPco process introduces cold iron pentacarbonyl diluted in CO, or alternatively nitrogen, at high pressure, ca. 30 atmospheres into a conical mixing zone. Hot CO is also introduced via three jets at angles with respect to the axis of the reactor. Hot CO decomposes the Fe(CO)5 to release atomic Fe. Cluster reaction rates are from Krestinin, et aI., based on shock tube measurements. Another model is from classical cluster theory given by Girshick's team. The calculations are performed on streamlines that assume that a cold mixture of Fe(CO)5 in CO is introduced along the reactor axis. Then iron forms clusters that catalyze the formation of SWNTs from the Boudouard reaction on Fe-containing clusters by reaction with CO. To simulate the chemical process along streamlines that were calculated by the fluid dynamics code FLUENT, a time history of temperature and dilution are determined along streamlines. Alternative catalyst injection schemes are also evaluated.

  9. Effects of complex terrain on atmospheric flow: dividing streamline observations and quantification

    NASA Astrophysics Data System (ADS)

    Thompson, Michael; Fernando, Harindra; di Sabatino, Silvana; Leo, Laura; University of Notre Dame Team

    2013-11-01

    As part of the MATERHORN field campaign on atmospheric flow in mountainous terrain, the dividing streamline concept for stratified flow over obstacles was investigated using smoke flow visualization and meteorological measurements. At small Froude numbers (Fr < 1), a stratified flow approaching a mountain either possesses enough kinetic energy to pass over the summit or else flow around the sides, with dividing streamlines separating the two scenarios. An isolated northwestern peak of the Granite Mountain, approximately 60 m in height, was used for the study. Incoming flow velocities and temperature profiles were measured upstream using sonic anemometers and thermocouples mounted on a 32 m tower, while onsite measurements were taken with portable weather stations. Sufficiently strong stratification was developed around 3:00AM GMT, with Froude numbers in the range for dividing streamlines to exist. In the first trial, suitably placed red smoke releases were used and in another trial white smoke was released from a 25 m crane. In both cases well-defined dividing streamlines were observed and its vertical location was at a height about half of the mountain height, which is consistent with theoretical results based on Shepard's formula. This research was supported by the Office of Naval Research (ONR) grant number N00014-11-1-0709.

  10. Planetary rings - Theory

    NASA Technical Reports Server (NTRS)

    Borderies, Nicole

    1989-01-01

    Theoretical models of planetary-ring dynamics are examined in a brief analytical review. The mathematical description of streamlines and streamline interactions is outlined; the redistribution of angular momentum due to collisions between particles is explained; and problems in the modeling of broad, narrow, and arc rings are discussed.

  11. A case study of development and application of a streamlined control and response modeling system for PM2.5 attainment assessment in China.

    PubMed

    Long, Shicheng; Zhu, Yun; Jang, Carey; Lin, Che-Jen; Wang, Shuxiao; Zhao, Bin; Gao, Jian; Deng, Shuang; Xie, Junping; Qiu, Xuezhen

    2016-03-01

    This article describes the development and application of a streamlined air control and response modeling system with a novel response surface modeling-linear coupled fitting method and a new module to provide streamlined model data for PM2.5 attainment assessment in China. This method is capable of significantly reducing the dimensions required to establish a response surface model, as well as capturing more realistic response of PM2.5 to emission changes with a limited number of model simulations. The newly developed module establishes a data link between the system and the Software for Model Attainment Test-Community Edition (SMAT-CE), and has the ability to rapidly provide model responses to emission control scenarios for SMAT-CE using a simple interface. The performance of this streamlined system is demonstrated through a case study of the Yangtze River Delta (YRD) in China. Our results show that this system is capable of reproducing the Community Multi-Scale Air Quality (CMAQ) model simulation results with maximum mean normalized error<3.5%. It is also demonstrated that primary emissions make a major contribution to ambient levels of PM2.5 in January and August (e.g., more than 50% contributed by primary emissions in Shanghai), and Shanghai needs to have regional emission control both locally and in its neighboring provinces to meet China's annual PM2.5 National Ambient Air Quality Standard. The streamlined system provides a real-time control/response assessment to identify the contributions of major emission sources to ambient PM2.5 (and potentially O3 as well) and streamline air quality data for SMAT-CE to perform attainment assessments. Copyright © 2015. Published by Elsevier B.V.

  12. Effects of microscale inertia on heat or mass transfer from a drop

    NASA Astrophysics Data System (ADS)

    Krishnamurthy, Deepak; Subramanian, Ganesh

    2012-11-01

    Heat or mass transport from suspensions of solid particles or drops is ubiquitous in many industrial processes. In the zero inertia limit the transport is diffusion limited owing to the presence of closed streamlines around each particle. A small but finite amount of inertia though, results in a vastly different picture, greatly enhancing transport by destroying the closed streamline configuration. We develop a theoretical formulation to study the effects of weak inertia on transport from a density-matched drop in a 2D linear flow. It is shown that, unlike a solid particle, the near-surface streamlines are closed only when the viscosity ratio (λ) exceeds a critical value λc = 2 α / (1- α) , where α is the linear flow parameter measuring relative magnitudes of extension and vorticity. The velocity field on the drop surface can be characterized using a complex-valued analogue of the (C, τ) coordinate system used to describe Jeffrey orbits of an axisymmetric particle. In the open-streamline case (λ < λ c) , convective transport occurs even with zero inertia, and for large Peclet number (Pe) (the relative magnitude of convective to diffusive transport), the Nusselt number (dimensionless rate of heat transfer) is expected to scale as F(α, λ) Pe1/2 and is determined via a boundary layer analysis in the (C, τ) coordinate system. In the closed streamline case (λ > λ c) , similar to the solid particle, inertia plays a crucial role, and the Nusselt number must scale as G(α, λ)Re1/2Pe1/2. A methodology is developed to analyze the convection along spiraling streamlines using a physically motivated choice of coordinate system on the drop surface.

  13. 76 FR 24339 - Streamlining Service Delivery and Improving Customer Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... Order 13571 of April 27, 2011 Streamlining Service Delivery and Improving Customer Service By the... Customer Service Standards), issued on September 11, 1993, requires agencies that provide significant services directly to the public to identify and survey their customers, establish service standards and...

  14. 78 FR 44981 - Restructuring of National Labor Relations Board's Headquarters' Offices

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ... Operations-Management to the Ethics, Employment and Administrative Law Branch of the Division of Legal... delivery of services, and streamline, integrate and enhance management functions. DATES: Effective Date... duplication of functions, improve the delivery of services, and streamline, integrate and enhance management...

  15. Simplified 4-Step Transportation Planning Process For Any Sized Area

    DOT National Transportation Integrated Search

    1999-01-01

    This paper presents a streamlined version of the Washington, D.C. region's : 4-step travel demand forecasting model. The purpose for streamlining the : model was to have a model that could: replicate the regional model, and be run : in a new s...

  16. Brownfields Assessing Contractor Capabilities for Streamlined Site Investigation: Additional Information Regarding All Appropriate Inquiries and Hiring an Environmental Professional

    EPA Pesticide Factsheets

    This document assists Brownfields grantees and other decision makers as they assess the capabilities of contractors and consultants to determine their qualifications to provide streamlined and innovative strategies for the assessment and and cleanup.

  17. Investigation of smoothness-increasing accuracy-conserving filters for improving streamline integration through discontinuous fields.

    PubMed

    Steffen, Michael; Curtis, Sean; Kirby, Robert M; Ryan, Jennifer K

    2008-01-01

    Streamline integration of fields produced by computational fluid mechanics simulations is a commonly used tool for the investigation and analysis of fluid flow phenomena. Integration is often accomplished through the application of ordinary differential equation (ODE) integrators--integrators whose error characteristics are predicated on the smoothness of the field through which the streamline is being integrated--smoothness which is not available at the inter-element level of finite volume and finite element data. Adaptive error control techniques are often used to ameliorate the challenge posed by inter-element discontinuities. As the root of the difficulties is the discontinuous nature of the data, we present a complementary approach of applying smoothness-enhancing accuracy-conserving filters to the data prior to streamline integration. We investigate whether such an approach applied to uniform quadrilateral discontinuous Galerkin (high-order finite volume) data can be used to augment current adaptive error control approaches. We discuss and demonstrate through numerical example the computational trade-offs exhibited when one applies such a strategy.

  18. Supersonic Flow of Chemically Reacting Gas-Particle Mixtures. Volume 2: RAMP - A Computer Code for Analysis of Chemically Reacting Gas-Particle Flows

    NASA Technical Reports Server (NTRS)

    Penny, M. M.; Smith, S. D.; Anderson, P. G.; Sulyma, P. R.; Pearson, M. L.

    1976-01-01

    A computer program written in conjunction with the numerical solution of the flow of chemically reacting gas-particle mixtures was documented. The solution to the set of governing equations was obtained by utilizing the method of characteristics. The equations cast in characteristic form were shown to be formally the same for ideal, frozen, chemical equilibrium and chemical non-equilibrium reacting gas mixtures. The characteristic directions for the gas-particle system are found to be the conventional gas Mach lines, the gas streamlines and the particle streamlines. The basic mesh construction for the flow solution is along streamlines and normals to the streamlines for axisymmetric or two-dimensional flow. The analysis gives detailed information of the supersonic flow and provides for a continuous solution of the nozzle and exhaust plume flow fields. Boundary conditions for the flow solution are either the nozzle wall or the exhaust plume boundary.

  19. The self streamlining wind tunnel. [wind tunnel walls

    NASA Technical Reports Server (NTRS)

    Goodyer, M. J.

    1975-01-01

    A two dimensional test section in a low speed wind tunnel capable of producing flow conditions free from wall interference is presented. Flexible top and bottom walls, and rigid sidewalls from which models were mounted spanning the tunnel are shown. All walls were unperforated, and the flexible walls were positioned by screw jacks. To eliminate wall interference, the wind tunnel itself supplied the information required in the streamlining process, when run with the model present. Measurements taken at the flexible walls were used by the tunnels computer check wall contours. Suitable adjustments based on streamlining criteria were then suggested by the computer. The streamlining criterion adopted when generating infinite flowfield conditions was a matching of static pressures in the test section at a wall with pressures computed for an imaginary inviscid flowfield passing over the outside of the same wall. Aerodynamic data taken on a cylindrical model operating under high blockage conditions are presented to illustrate the operation of the tunnel in its various modes.

  20. Mapping population-based structural connectomes.

    PubMed

    Zhang, Zhengwu; Descoteaux, Maxime; Zhang, Jingwen; Girard, Gabriel; Chamberland, Maxime; Dunson, David; Srivastava, Anuj; Zhu, Hongtu

    2018-05-15

    Advances in understanding the structural connectomes of human brain require improved approaches for the construction, comparison and integration of high-dimensional whole-brain tractography data from a large number of individuals. This article develops a population-based structural connectome (PSC) mapping framework to address these challenges. PSC simultaneously characterizes a large number of white matter bundles within and across different subjects by registering different subjects' brains based on coarse cortical parcellations, compressing the bundles of each connection, and extracting novel connection weights. A robust tractography algorithm and streamline post-processing techniques, including dilation of gray matter regions, streamline cutting, and outlier streamline removal are applied to improve the robustness of the extracted structural connectomes. The developed PSC framework can be used to reproducibly extract binary networks, weighted networks and streamline-based brain connectomes. We apply the PSC to Human Connectome Project data to illustrate its application in characterizing normal variations and heritability of structural connectomes in healthy subjects. Copyright © 2018 Elsevier Inc. All rights reserved.

  1. Effect of nose shape on three-dimensional stagnation region streamlines and heating rates

    NASA Technical Reports Server (NTRS)

    Hassan, Basil; Dejarnette, Fred R.; Zoby, E. V.

    1991-01-01

    A new method for calculating the three-dimensional inviscid surface streamlines and streamline metrics using Cartesian coordinates and time as the independent variable of integration has been developed. The technique calculates the streamline from a specified point on the body to a point near the stagnation point by using a prescribed pressure distribution in the Euler equations. The differential equations, which are singular at the stagnation point, are of the two point boundary value problem type. Laminar heating rates are calculated using the axisymmetric analog concept for three-dimensional boundary layers and approximate solutions to the axisymmetric boundary layer equations. Results for elliptic conic forebody geometries show that location of the point of maximum heating depends on the type of conic in the plane of symmetry and the angle of attack, and that this location is in general different from the stagnation point. The new method was found to give smooth predictions of heat transfer in the nose region where previous methods gave oscillatory results.

  2. Kasei Vallis Streamlined Island

    NASA Image and Video Library

    2002-12-13

    Except for the loss of its ring of ejecta, the crater at the leading edge of this streamlined island in Kasei Vallis, imaged here by NASA Mars Odyssey, shows no hint of the catastrophic floods that passed by it. Kasei Vallis is one of several major outflow channel systems that were active over 3 billion years ago. The intense floods scoured the landscape, eroding craters and producing streamlined islands. But in a close-up view, the evidence for these floods is not apparent. This true of the most similar terrestrial example, the channeled scablands of eastern Washington which also were formed by a catastrophic flood. http://photojournal.jpl.nasa.gov/catalog/PIA04022

  3. Analysis of Streamline Separation at Infinity Using Time-Discrete Markov Chains.

    PubMed

    Reich, W; Scheuermann, G

    2012-12-01

    Existing methods for analyzing separation of streamlines are often restricted to a finite time or a local area. In our paper we introduce a new method that complements them by allowing an infinite-time-evaluation of steady planar vector fields. Our algorithm unifies combinatorial and probabilistic methods and introduces the concept of separation in time-discrete Markov-Chains. We compute particle distributions instead of the streamlines of single particles. We encode the flow into a map and then into a transition matrix for each time direction. Finally, we compare the results of our grid-independent algorithm to the popular Finite-Time-Lyapunov-Exponents and discuss the discrepancies.

  4. Empty test section streamlining of the transonic self-streamlining wind tunnel fitted with new walls

    NASA Technical Reports Server (NTRS)

    Lewis, M. C.

    1988-01-01

    The original flexible top and bottom walls of the Transonic Self-Streamlining Wind Tunnel (TSWT), at the University of Southampton, have been replaced with new walls featuring a larger number of static pressure tappings and detailed mechanical improvements. This report describes the streamling method, results, and conclusions of a series of tests aimed at defining sets of aerodynamically straight wall contours for the new flexible walls. This procedure is a necessary prelude to model testing. The quality of data obtained compares favorably with the aerodynamically straight data obtained with the old walls. No operational difficulties were experienced with the new walls.

  5. 77 FR 23278 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Workforce...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ... (ETA) sponsored information collection request (ICR) titled, ``Workforce Investment Streamlined... this request to the Office of Information and Regulatory Affairs, Attn: OMB Desk Officer for DOL-ETA... electronic submission of responses. Agency: DOL-ETA. Title of Collection: Workforce Investment Streamlined...

  6. 78 FR 21118 - Agency Information Collection Activities; Comment Request; Streamlined Clearance Process for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-09

    ...; Comment Request; Streamlined Clearance Process for Discretionary Grants AGENCY: Department of Education... also helps the public understand the Department's information collection requirements and provide the... for Discretionary Grants OMB Control Number: 1894-0001 Type of Review: An extension of an existing...

  7. 78 FR 36677 - Radio Experimentation and Market Trials-Streamlining Rules

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... Experimentation and Market Trials--Streamlining Rules AGENCY: Federal Communications Commission. ACTION: Final rule. SUMMARY: In this document the Commission modifies on its own motion the rules adopted in this... being conducted under a program, medical testing, and compliance testing license. Thus, this action will...

  8. Lidar - DOE ARM StreamLine Doppler Lidar (Halo) - Raw Data

    DOE Data Explorer

    Newsom, Rob

    2017-11-20

    1. Evaluate performance of the Halo Photonics Streamline lidar against a calibrated reference (i.e. the BAO tower). 2. Provide measurements of vertical velocity for use with other scanning lidars to better constrain velocity retrievals. 3. Provide colocated reference for comparison with Vindicator lidars.

  9. West Virginia Peer Exchange : Streamlining Highway Safety Improvement Program Project Delivery - An RSPCB Peer Exchange

    DOT National Transportation Integrated Search

    2014-09-01

    The West Virginia Division of Highways (WV DOH) hosted a Peer Exchange to share information and experiences for streamlining Highway Safety Improvement Program (HSIP) project delivery. The event was held September 23 to 24, 2014 in Charleston, West V...

  10. Brownfields Assessing Contractor Capabilities for Streamlined Site Investigations -- Additional Information Regarding All Appropriate Inquiries and Hiring an Environmental Professional (November 2006)

    EPA Pesticide Factsheets

    Guidance for Brownfields grantees and other decision makers to assess the capabilities of contractors and consultants to determine their qualifications to provide streamlined and innovative strategies for the assessment and cleanup of brownfields.

  11. The design of the Comet streamliner: An electric land speed record motorcycle

    NASA Astrophysics Data System (ADS)

    McMillan, Ethan Alexander

    The development of the land speed record electric motorcycle streamliner, the Comet, is discussed herein. Its design process includes a detailed literary review of past and current motorcycle streamliners in an effort to highlight the main components of such a vehicle's design, while providing baseline data for performance comparisons. A new approach to balancing a streamliner at low speeds is also addressed, a system henceforth referred to as landing gear, which has proven an effective means for allowing the driver to control the low speed instabilities of the vehicle with relative ease compared to tradition designs. This is accompanied by a dynamic stability analysis conducted on a test chassis that was developed for the primary purpose of understanding the handling dynamics of streamliners, while also providing a test bed for the implementation of the landing gear system and a means to familiarize the driver to the operation and handling of such a vehicle. Data gathered through the use of GPS based velocity tracking, accelerometers, and a linear potentiometer provided a means to validate a dynamic stability analysis of the weave and wobble modes of the vehicle through linearization of a streamliner model developed in the BikeSIM software suite. Results indicate agreement between the experimental data and the simulation, indicating that the conventional recumbent design of a streamliner chassis is in fact highly stable throughout the performance envelope beyond extremely low speeds. A computational fluid dynamics study was also performed, utilized in the development of the body of the Comet to which a series of tests were conducted in order to develop a shape that was both practical to transport and highly efficient. By creating a hybrid airfoil from a NACA 0018 and NACA 66-018, a drag coefficient of 0.1 and frontal area of 0.44 m2 has been found for the final design. Utilizing a performance model based on the proposed vehicle's motor, its rolling resistance, and the body's aerodynamic drag, the top speed is predicted at 226 mph. Further design considerations are also addressed, including the development of the component level layout of the motorcycle, weighing factors such as safety and ease of fabrication with that of performance and accessibility. At the time of composition, the Comet had started the fabrication process, and it is the intent of the author that the finished product competes in the 2016 Bonneville Motorcycle Speed Trials to set the first world record for a single track electric motorcycle streamliner.

  12. Out-of-Core Streamline Visualization on Large Unstructured Meshes

    NASA Technical Reports Server (NTRS)

    Ueng, Shyh-Kuang; Sikorski, K.; Ma, Kwan-Liu

    1997-01-01

    It's advantageous for computational scientists to have the capability to perform interactive visualization on their desktop workstations. For data on large unstructured meshes, this capability is not generally available. In particular, particle tracing on unstructured grids can result in a high percentage of non-contiguous memory accesses and therefore may perform very poorly with virtual memory paging schemes. The alternative of visualizing a lower resolution of the data degrades the original high-resolution calculations. This paper presents an out-of-core approach for interactive streamline construction on large unstructured tetrahedral meshes containing millions of elements. The out-of-core algorithm uses an octree to partition and restructure the raw data into subsets stored into disk files for fast data retrieval. A memory management policy tailored to the streamline calculations is used such that during the streamline construction only a very small amount of data are brought into the main memory on demand. By carefully scheduling computation and data fetching, the overhead of reading data from the disk is significantly reduced and good memory performance results. This out-of-core algorithm makes possible interactive streamline visualization of large unstructured-grid data sets on a single mid-range workstation with relatively low main-memory capacity: 5-20 megabytes. Our test results also show that this approach is much more efficient than relying on virtual memory and operating system's paging algorithms.

  13. Improving Productivity in Copyright Registration. Report by the U.S. General Accounting Office.

    ERIC Educational Resources Information Center

    Comptroller General of the U.S., Washington, DC.

    The productivity of the copyright registration process, which is administered by the Copyright Office within the Library of Congress, can be improved by streamlining the workflow, reducing and streamlining the handling of correspondence, measuring productivity/performance, increasing the use of automation, improving records management, and…

  14. Honest broker protocol streamlines research access to data while safeguarding patient privacy.

    PubMed

    Silvey, Scott A; Silvey, Scott Andrew; Schulte, Janet; Smaltz, Detlev H; Smaltz, Detlev Herb; Kamal, Jyoti

    2008-11-06

    At Ohio State University Medical Center, The Honest Broker Protocol provides a streamlined mechanism whereby investigators can obtain de-identified clinical data for non-FDA research without having to invest the significant time and effort necessary to craft a formalized protocol for IRB approval.

  15. Streamlining the Bankability Process using International Standards

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kurtz, Sarah; Repins, Ingrid L; Kelly, George

    NREL has supported the international efforts to create a streamlined process for documenting bankability and/or completion of each step of a PV project plan. IECRE was created for this purpose in 2014. This poster describes the goals, current status of this effort, and how individuals and companies can become involved.

  16. 48 CFR 13.005 - Federal Acquisition Streamlining Act of 1994 list of inapplicable laws.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Federal Acquisition Streamlining Act of 1994 list of inapplicable laws. 13.005 Section 13.005 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES SIMPLIFIED ACQUISITION...

  17. 48 CFR 13.005 - Federal Acquisition Streamlining Act of 1994 list of inapplicable laws.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Federal Acquisition Streamlining Act of 1994 list of inapplicable laws. 13.005 Section 13.005 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES SIMPLIFIED ACQUISITION...

  18. 48 CFR 13.005 - Federal Acquisition Streamlining Act of 1994 list of inapplicable laws.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Federal Acquisition Streamlining Act of 1994 list of inapplicable laws. 13.005 Section 13.005 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES SIMPLIFIED ACQUISITION...

  19. 48 CFR 13.005 - Federal Acquisition Streamlining Act of 1994 list of inapplicable laws.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Federal Acquisition Streamlining Act of 1994 list of inapplicable laws. 13.005 Section 13.005 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES SIMPLIFIED ACQUISITION...

  20. Use of Vortex Generators to Reduce Distortion for Mach 1.6 Streamline-Traced Supersonic Inlets

    NASA Technical Reports Server (NTRS)

    Baydar, Ezgihan; Lu, Frank; Slater, John W.; Trefny, Chuck

    2016-01-01

    Reduce the total pressure distortion at the engine-fan face due to low-momentum flow caused by the interaction of an external terminal shock at the turbulent boundary layer along a streamline-traced external-compression (STEX) inlet for Mach 1.6.

  1. Report: Follow-Up Report: EPA Proposes to Streamline the Review, Management and Disposal of Hazardous Waste Pharmaceuticals

    EPA Pesticide Factsheets

    Report #15-P-0260, August 19, 2015. EPA states that it intends to issue a proposed rule, Management Standards for Hazardous Waste, which will attempt to streamline the approach to managing and disposing of hazardous and nonhazardous pharmaceutical waste.

  2. Optically Based Rapid Screening Method for Proven Optimal Treatment Strategies Before Treatment Begins

    DTIC Science & Technology

    to rapidly test /screen breast cancer therapeutics as a strategy to streamline drug development and provide individualized treatment. The results...system can therefore be used to streamline pre-clinical drug development, by reducing the number of animals , cost, and time required to screen new drugs

  3. 75 FR 29321 - Streamlined Procedure for Appeal Brief Review in Ex Parte Reexamination Proceedings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-25

    ... DEPARTMENT OF COMMERCE Patent and Trademark Office [Docket No.: PTO-P-2010-0046] Streamlined... Trademark Office, Commerce. ACTION: Notice. SUMMARY: The United States Patent and Trademark Office (USPTO... Intellectual Property and Director of the United States Patent and Trademark Office. [FR Doc. 2010-12534 Filed...

  4. Streamlining: Reducing costs and increasing STS operations effectiveness

    NASA Technical Reports Server (NTRS)

    Petersburg, R. K.

    1985-01-01

    The development of streamlining as a concept, its inclusion in the space transportation system engineering and operations support (STSEOS) contract, and how it serves as an incentive to management and technical support personnel is discussed. The mechanics of encouraging and processing streamlining suggestions, reviews, feedback to submitters, recognition, and how individual employee performance evaluations are used to motivation are discussed. Several items that were implemented are mentioned. Information reported and the methodology of determining estimated dollar savings are outlined. The overall effect of this activity on the ability of the McDonnell Douglas flight preparation and mission operations team to support a rapidly increasing flight rate without a proportional increase in cost is illustrated.

  5. 76 FR 814 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Order Approving a Proposed Rule Change To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-06

    ... proposes to establish new minimum performance standards for specialist units.\\12\\ Specifically, new Rule... Streamline the Process for Specialist Evaluations and Clarify the Time Within Which SQTs and RSQTs Must Begin...-4 thereunder,\\2\\ a proposed rule change to update and streamline the process for specialist...

  6. 77 FR 21908 - Approval and Promulgation of Air Quality Implementation Plans; Pennsylvania; Streamlining...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ... permit or a Title V permit, ``* * * to permit the evaluation of the air contamination aspects of the... Promulgation of Air Quality Implementation Plans; Pennsylvania; Streamlining Amendments to the Plan Approval... Air Act (CAA). DATES: Written comments must be received on or before May 14, 2012. ADDRESSES: Submit...

  7. 78 FR 57058 - Federal Housing Administration (FHA) Approval of Lending Institutions and Mortgagees: Streamlined...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ... federal banking agencies and reduce the cost of participating in FHA programs by releasing small... retained earnings, a statement of cash flows, an analysis of the lender's or mortgagee's net worth adjusted...: Streamlined Reporting Requirements for Small Supervised Lenders and Mortgagees AGENCY: Office of the Assistant...

  8. 78 FR 23178 - Federal Housing Administration (FHA) Approval of Lending Institutions and Mortgagees: Streamlined...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-18

    ... in line with that of the federal banking agencies and, as discussed above, reduce the cost of... earnings, a statement of cash flows, an analysis of the mortgagee's net worth adjusted to reflect only...: Streamlined Reporting Requirements for Small Supervised Lenders and Mortgagees AGENCY: Office of the Assistant...

  9. Streamlining the Online Course Development Process by Using Project Management Tools

    ERIC Educational Resources Information Center

    Abdous, M'hammed; He, Wu

    2008-01-01

    Managing the design and production of online courses is challenging. Insufficient instructional design and inefficient management often lead to issues such as poor course quality and course delivery delays. In an effort to facilitate, streamline, and improve the overall design and production of online courses, this article discusses how we…

  10. 77 FR 41774 - Notice of Final Environmental Assessment and Finding of No Significant Impact for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-16

    ..., New York. A modernized facility is needed to streamline radioactive material handling and storage... waste shipments would be a small part of the shipments of radioactive materials made annually in the... preferred action to address the need for streamlining radioactive material handling and storage operations...

  11. 49 CFR 1503.421 - Streamlined civil penalty procedures for certain security violations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROCEDURAL RULES INVESTIGATIVE AND ENFORCEMENT PROCEDURES Assessment of Civil Penalties by TSA § 1503.421 Streamlined civil penalty procedures for certain security violations. (a) Notice of violation. TSA, at the... violations described in the section and as otherwise provided by the Administrator. TSA may serve a Notice of...

  12. Overhead Projection Cell for Streamline Flow

    ERIC Educational Resources Information Center

    Waage, Harold M.

    1969-01-01

    Describes the construction and operation of an overhead projection apparatus designed to demonstrate streamline flow of a liquid. The apparatus consists of a Plexiglass tank containing water in which plates forming the cell are submerged, a constant level reservoir, an overflow device and a system for marking the flow lines with a dye. (LC)

  13. 76 FR 54792 - Comment Request for Information Collection for the Workforce Investment Act Streamlined...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-02

    ... organizations. Form(s): ETA-9131, ETA-9132, ETA 9133, WISRD Record Layout, WISPR Data Preparation and Reporting... Collection for the Workforce Investment Act Streamlined Performance Reporting (WISPR) Data Collection System... requested data can be provided in the desired format, reporting burden (time and financial resources) is...

  14. 24 CFR 903.12 - What are the streamlined Annual Plan requirements for small PHAs?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Plan requirements for small PHAs? 903.12 Section 903.12 Housing and Urban Development Regulations... HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT PUBLIC HOUSING AGENCY PLANS PHA Plans § 903.12 What are the streamlined Annual Plan requirements for small PHAs? (a) General. PHAs with less than 250...

  15. Calculation of heat transfer on shuttle type configurations including the effects of variable entropy at boundary layer edge

    NASA Technical Reports Server (NTRS)

    Dejarnette, F. R.

    1972-01-01

    A relatively simple method is presented for including the effect of variable entropy at the boundary-layer edge in a heat transfer method developed previously. For each inviscid surface streamline an approximate shockwave shape is calculated using a modified form of Maslen's method for inviscid axisymmetric flows. The entropy for the streamline at the edge of the boundary layer is determined by equating the mass flux through the shock wave to that inside the boundary layer. Approximations used in this technique allow the heating rates along each inviscid surface streamline to be calculated independent of the other streamlines. The shock standoff distances computed by the present method are found to compare well with those computed by Maslen's asymmetric method. Heating rates are presented for blunted circular and elliptical cones and a typical space shuttle orbiter at angles of attack. Variable entropy effects are found to increase heating rates downstream of the nose significantly higher than those computed using normal-shock entropy, and turbulent heating rates increased more than laminar rates. Effects of Reynolds number and angles of attack are also shown.

  16. An investigation of the internal and external aerodynamics of cattle trucks

    NASA Technical Reports Server (NTRS)

    Muirhead, V. U.

    1983-01-01

    Wind tunnel tests were conducted on a one-tenth scale model of a conventional tractor trailer livestock hauler to determine the air flow through the trailer and the drag of the vehicle. These tests were conducted with the trailer empty and with a full load of simulated cattle. Additionally, the drag was determined for six configurations, of which details for three are documented herein. These are: (1) conventional livestock trailer empty, (2) conventional trailer with smooth sides (i.e., without ventilation openings), and (3) a stream line tractor with modified livestock trailer (cab streamlining and gap fairing). The internal flow of the streamlined modification with simulated cattle was determined with two different ducting systems: a ram air inlet over the cab and NACA submerged inlets between the cab and trailer. The air flow within the conventional trailer was random and variable. The streamline vehicle with ram air inlet provided a nearly uniform air flow which could be controlled. The streamline vehicle with NACA submerged inlets provided better flow conditions than the conventional livestock trailer but not as uniform or controllable as the ram inlet configuration.

  17. Virtual Genomes in Flux: An Interplay of Neutrality and Adaptability Explains Genome Expansion and Streamlining

    PubMed Central

    Cuypers, Thomas D.; Hogeweg, Paulien

    2012-01-01

    The picture that emerges from phylogenetic gene content reconstructions is that genomes evolve in a dynamic pattern of rapid expansion and gradual streamlining. Ancestral organisms have been estimated to possess remarkably rich gene complements, although gene loss is a driving force in subsequent lineage adaptation and diversification. Here, we study genome dynamics in a model of virtual cells evolving to maintain homeostasis. We observe a pattern of an initial rapid expansion of the genome and a prolonged phase of mutational load reduction. Generally, load reduction is achieved by the deletion of redundant genes, generating a streamlining pattern. Load reduction can also occur as a result of the generation of highly neutral genomic regions. These regions can expand and contract in a neutral fashion. Our study suggests that genome expansion and streamlining are generic patterns of evolving systems. We propose that the complex genotype to phenotype mapping in virtual cells as well as in their biological counterparts drives genome size dynamics, due to an emerging interplay between adaptation, neutrality, and evolvability. PMID:22234601

  18. Comparative Evaluation of Flow Quantification across the Atrioventricular Valve in Patients with Functional Univentricular Heart after Fontan's Surgery and Healthy Controls: Measurement by 4D Flow Magnetic Resonance Imaging and Streamline Visualization.

    PubMed

    She, Hoi Lam; Roest, Arno A W; Calkoen, Emmeline E; van den Boogaard, Pieter J; van der Geest, Rob J; Hazekamp, Mark G; de Roos, Albert; Westenberg, Jos J M

    2017-01-01

    To evaluate the inflow pattern and flow quantification in patients with functional univentricular heart after Fontan's operation using 4D flow magnetic resonance imaging (MRI) with streamline visualization when compared with the conventional 2D flow approach. Seven patients with functional univentricular heart after Fontan's operation and twenty-three healthy controls underwent 4D flow MRI. In two orthogonal two-chamber planes, streamline visualization was applied, and inflow angles with peak inflow velocity (PIV) were measured. Transatrioventricular flow quantification was assessed using conventional 2D multiplanar reformation (MPR) and 4D MPR tracking the annulus and perpendicular to the streamline inflow at PIV, and they were validated with net forward aortic flow. Inflow angles at PIV in the patient group demonstrated wide variation of angles and directions when compared with the control group (P < .01). The use of 4D flow MRI with streamlines visualization in quantification of the transatrioventricular flow had smaller limits of agreement (2.2 ± 4.1 mL; 95% limit of agreement -5.9-10.3 mL) when compared with the static plane assessment from 2DFlow MRI (-2.2 ± 18.5 mL; 95% limit of agreement agreement -38.5-34.1 mL). Stronger correlation was present in the 4D flow between the aortic and trans-atrioventricular flow (R 2 correlation in 4D flow: 0.893; in 2D flow: 0.786). Streamline visualization in 4D flow MRI confirmed variable atrioventricular inflow directions in patients with functional univentricular heart with previous Fontan's procedure. 4D flow aided generation of measurement planes according to the blood flood dynamics and has proven to be more accurate than the fixed plane 2D flow measurements when calculating flow quantifications. © 2016 Wiley Periodicals, Inc.

  19. 78 FR 49680 - Streamlining Requirements Governing the Use of Funding for Supportive Housing for the Elderly and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-15

    ...-AI67 Streamlining Requirements Governing the Use of Funding for Supportive Housing for the Elderly and... mixed finance developments in the Section 202 Supportive Housing for the Elderly (Section 202) and the.... Accordingly, HUD amends 24 CFR part 891 as follows: PART 891--SUPPORTIVE HOUSING FOR THE ELDERLY AND PERSONS...

  20. An Operationally Responsive Space Architecture for 2025

    DTIC Science & Technology

    2008-06-22

    Organizational Relationships, Asset Loss Mitigation, Availability, Flexibility, and Streamlined Acquisition Processes . These pillars allowed the solutions...were considered. Analysis was further supported by a performance versus cost process which provided a final test of solution feasibility. Relative cost...Availability, Flexibility, and Streamlined Acquisition Processes . These pillars allowed the solutions, material and non-material, to be organized for

  1. EBSCO's Usage Consolidation Attempts to Streamline Gathering, Storage, and Reporting of Usage Statistics

    ERIC Educational Resources Information Center

    Remy, Charlie

    2012-01-01

    This paper provides an overview of EBSCO's new Usage Consolidation product designed to streamline the harvesting, storage, and analysis of usage statistics from electronic resources. Strengths and weaknesses of the product are discussed as well as an early beta partner's experience. In the current atmosphere of flat or declining budgets, libraries…

  2. Streamline Basal Application of Herbicide for Small-Stem Hardwood Control

    Treesearch

    James H. Miller

    1990-01-01

    Abstract. The effectiveness of low-volume b a s a lapplication of herbicide - "streamline" application - was evaluated on 25 hardwood species and loblolly pine. Test mixtures were step-wise rates of Garlon 4 mixed in diesel fuel with a penatrant added. Most comparisons tested 1O%, 20%, and 30% mixtures of Garlon 4, while tests with...

  3. Implementing an Enterprise Information System to Reengineer and Streamline Administrative Processes in a Distance Learning Unit

    ERIC Educational Resources Information Center

    Abdous, M'hammed; He, Wu

    2009-01-01

    During the past three years, we have developed and implemented an enterprise information system (EIS) to reengineer and facilitate the administrative process for preparing and teaching distance learning courses in a midsized-to-large university (with 23,000 students). The outcome of the implementation has been a streamlined and efficient process…

  4. Effective Report Preparation: Streamlining the Reporting Process. AIR 1999 Annual Forum Paper.

    ERIC Educational Resources Information Center

    Dalrymple, Margaret; Wang, Mindy; Frost, Jacquelyn

    This paper describes the processes and techniques used to improve and streamline the standard student reports used at Purdue University (Indiana). Various models for analyzing reporting processes are described, especially the model used in the study, the Shewart or Deming Cycle, a method that aids in continuous analysis and improvement through a…

  5. Surface waves with high angular momentum: leakage from remote caustics, and tightly coiled streamlines

    NASA Astrophysics Data System (ADS)

    Berry, M. V.

    2018-07-01

    Outgoing cylindrical waves scattered by a disk, or emerging from a source inside it, are represented by Hankel functions of order m. For large m, these waves decay rapidly outside the disk and resemble radially evanescent surface waves travelling around it. But they eventually leak weakly away, in a manner described accurately by the asymptotics of the Hankel function. The transition occurs at radial distance ∣m∣ (in wavelength units), which constitutes a circular caustic from which the radiation leaking out, described by the streamlines, appears to issue tangentially. In the evanescent region, the streamlines form spirals, whose windings get exponentially closer nearer the disk. These insights are intended to help graduate students demystify mathematics associated with scattering theory.

  6. Recognition of white matter bundles using local and global streamline-based registration and clustering.

    PubMed

    Garyfallidis, Eleftherios; Côté, Marc-Alexandre; Rheault, Francois; Sidhu, Jasmeen; Hau, Janice; Petit, Laurent; Fortin, David; Cunanne, Stephen; Descoteaux, Maxime

    2018-04-15

    Virtual dissection of diffusion MRI tractograms is cumbersome and needs extensive knowledge of white matter anatomy. This virtual dissection often requires several inclusion and exclusion regions-of-interest that make it a process that is very hard to reproduce across experts. Having automated tools that can extract white matter bundles for tract-based studies of large numbers of people is of great interest for neuroscience and neurosurgical planning. The purpose of our proposed method, named RecoBundles, is to segment white matter bundles and make virtual dissection easier to perform. This can help explore large tractograms from multiple persons directly in their native space. RecoBundles leverages latest state-of-the-art streamline-based registration and clustering to recognize and extract bundles using prior bundle models. RecoBundles uses bundle models as shape priors for detecting similar streamlines and bundles in tractograms. RecoBundles is 100% streamline-based, is efficient to work with millions of streamlines and, most importantly, is robust and adaptive to incomplete data and bundles with missing components. It is also robust to pathological brains with tumors and deformations. We evaluated our results using multiple bundles and showed that RecoBundles is in good agreement with the neuroanatomical experts and generally produced more dense bundles. Across all the different experiments reported in this paper, RecoBundles was able to identify the core parts of the bundles, independently from tractography type (deterministic or probabilistic) or size. Thus, RecoBundles can be a valuable method for exploring tractograms and facilitating tractometry studies. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Connectivity between the superior colliculus and the amygdala in humans and macaque monkeys: virtual dissection with probabilistic DTI tractography

    PubMed Central

    Koller, Kristin; Bultitude, Janet H.; Mullins, Paul; Ward, Robert; Mitchell, Anna S.; Bell, Andrew H.

    2015-01-01

    It has been suggested that some cortically blind patients can process the emotional valence of visual stimuli via a fast, subcortical pathway from the superior colliculus (SC) that reaches the amygdala via the pulvinar. We provide in vivo evidence for connectivity between the SC and the amygdala via the pulvinar in both humans and rhesus macaques. Probabilistic diffusion tensor imaging tractography revealed a streamlined path that passes dorsolaterally through the pulvinar before arcing rostrally to traverse above the temporal horn of the lateral ventricle and connect to the lateral amygdala. To obviate artifactual connectivity with crossing fibers of the stria terminalis, the stria was also dissected. The putative streamline between the SC and amygdala traverses above the temporal horn dorsal to the stria terminalis and is positioned medial to it in humans and lateral to it in monkeys. The topography of the streamline was examined in relation to lesion anatomy in five patients who had previously participated in behavioral experiments studying the processing of emotionally valenced visual stimuli. The pulvinar lesion interrupted the streamline in two patients who had exhibited contralesional processing deficits and spared the streamline in three patients who had no deficit. Although not definitive, this evidence supports the existence of a subcortical pathway linking the SC with the amygdala in primates. It also provides a necessary bridge between behavioral data obtained in future studies of neurological patients, and any forthcoming evidence from more invasive techniques, such as anatomical tracing studies and electrophysiological investigations only possible in nonhuman species. PMID:26224780

  8. A Zonal Approach for the Solution of Coupled Euler and Potential Solutions of Flows with Complex Geometries.

    DTIC Science & Technology

    1987-06-01

    obtained from: A simple numerical intergration scheme is employed to perform the integral in Equations (B2) and (86) along the dividing streamline. A 11 4...angle of attack was small, the dividing streamline remained almost horizontal in this case. Results of a higher angle of attack case, in which the mesh

  9. Expected Benefits of Streamlining Undergraduate Medical Education by Early Commitment to Specific Medical Specialties

    ERIC Educational Resources Information Center

    Benbassat, Jochanan; Baumal, Reuben

    2012-01-01

    Undergraduate medical education is too long; it does not meet the needs for physicians' workforce; and its content is inconsistent with the job characteristics of some of its graduates. In this paper we attempt to respond to these problems by streamlining medical education along the following three reforms. First, high school graduates would be…

  10. Streamlined Approach for Environmental Restoration Plan for Corrective Action Unit 489: WWII UXO Sites, Tonopah Test Range, Nevada; May 2005

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bechtel Nevada; U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office

    2005-05-01

    This Streamlined Approach for Environmental Restoration Plan provides the details for the closure of Corrective Action Unit (CAU) 489: WWII UXO Sites, Tonopah Test Range. CAU 489 is located at the Tonopah Test Range and is currently listed in Appendix III of the Federal Facility Agreement and Consent Order of 1996.

  11. On Periodic Water Waves with Coriolis Effects and Isobaric Streamlines

    NASA Astrophysics Data System (ADS)

    Matioc, Anca-Voichita; Matioc, Bogdan-Vasile

    2012-10-01

    In this paper we prove that solutions of the f-plane approximation for equatorial geophysical deep water waves, which have the property that the pressure is constant along the streamlines and do not possess stagnation points, are Gerstner-type waves. Furthermore, for waves traveling over a flat bed, we prove that there are only laminar flow solutions with these properties.

  12. Linking Surface Topography Variations To Subsurface Mixing And Reaction Patterns

    NASA Astrophysics Data System (ADS)

    Le Borgne, T.; Bandopadhyay, A.; Davy, P.

    2017-12-01

    Fluctuations in surface topography generate nested streamline patterns in the subsurface over scales ranging from millimeters to kilometers. Because solute residence times can be very different for each streamlines, these patterns exert a strong control on biogeochemical reactions. While this effect has been quantified in reactive transport models, solute transfer across streamlines has been generally neglected. Yet, this process can lead to significant solute dilution and may trigger reactions by mixing water with different chemical compositions. Considering topography-driven subsurface flow cells of different sizes, we show that the resulting streamline structures act as shear flows, with shear rates that can vary over orders of magnitude depending on scale, permeability and hydraulic head gradient. This leads to the formation of localized layers of enhanced dilution and reaction, where mixing rates can be orders of magnitude larger than diffusion limited rates (Bandopadhyay et al. under review). We develop a theoretical model that predicts the depth and magnitude of these mixing hotspots and quantifies the resulting exports of conservative and reactive chemical species at discharge locations. We discuss consequences of these findings by applying this model at hyporheic zone, hillslope, and catchment scales.

  13. The Effects of Propulsive Jetting on Drag of a Streamlined body

    NASA Astrophysics Data System (ADS)

    Krieg, Michael; Mohseni, Kamran

    2017-11-01

    Recently an abundance of bioinspired underwater vehicles have emerged to leverage eons of evolution. Our group has developed a propulsion technique inspired by jellyfish and squid. Propulsive jets are generated by ingesting and expelling water from a flexible internal cavity. We have demonstrated thruster capabilities for maneuvering on AUV platforms, where the internal thruster geometry minimized forward drag; however, such a setup cannot characterize propulsive efficiency. Therefore, we created a new streamlined vehicle platform that produces unsteady jets for forward propulsion rather than maneuvering. The streamlined jetting body is placed in a water tunnel and held stationary while jetting frequency and background flow velocity are varied. For each frequency/velocity pair the flow field is measured around the surface and in the wake using PIV. Using the zero jetting frequency as a baseline for each background velocity, the passive body drag is related to the velocity distribution. For cases with active jetting the drag and jetting forces are estimated from the velocity field and compared to the passive case. For this streamlined body, the entrainment of surrounding flow into the propulsive jet can reduce drag forces in addition to the momentum transfer of the jet itself. Office of Naval Research.

  14. CFD Prediction on the Pressure Distribution and Streamlines around an Isolated Single-Storey House Considering the Effect of Topographic Characteristics

    NASA Astrophysics Data System (ADS)

    Abdullah, J.; Zaini, S. S.; Aziz, M. S. A.; Majid, T. A.; Deraman, S. N. C.; Yahya, W. N. W.

    2018-04-01

    Single-storey houses are classified as low rise building and vulnerable to damages under windstorm event. This study was carried out with the aim to investigate the pressure distribution and streamlines around an isolated house by considering the effect of terrain characteristics. The topographic features such as flat, depression, ridge, and valley, are considered in this study. This simulation were analysed with Ansys FLUENT 14.0 software package. The result showed the topography characteristics influence the value of pressure coefficient and streamlines especially when the house was located at ridge terrain. The findings strongly suggested that wind analysis should include all topographic features in the analysis in order to establish the true wind force exerted on any structure.

  15. Applied Cognitive Task Analysis (ACTA) Methodology

    DTIC Science & Technology

    1997-11-01

    experienced based cognitive skills. The primary goal of this project was to develop streamlined methods of Cognitive Task Analysis that would fill this need...We have made important progression this direction. We have developed streamlined methods of Cognitive Task Analysis . Our evaluation study indicates...developed a CD-based stand alone instructional package, which will make the Applied Cognitive Task Analysis (ACTA) tools widely accessible. A survey of the

  16. Surface-Streamline Flow Visualization

    NASA Technical Reports Server (NTRS)

    Langston, L.; Boyle, M.

    1985-01-01

    Matrix of ink dots covers matte surface of polyester drafting film. Film placed against wind-tunnel wall. Layer of methyl salicylate (oil of wintergreen) sprayed over dotted area. Ink dot streaklines show several characteristics of flow, including primary saddle point of separations, primary horseshoe vortex and smaller vortex at cylinder/ endwall junction. Surface streamline flow visualization technique suitable for use in low-speed windtunnels or other low-speed gas flows.

  17. Imaging Gallium Nitride High Electron Mobility Transistors to Identify Point Defects

    DTIC Science & Technology

    2014-03-01

    streamline the sample preparation procedure to maximize the yield of successful samples to be analyzed chemically in an energy dispersive spectrometry...transmission electron microscope (STEM), sample preparation 15. NUMBER OF PAGES 103 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT...Computer Engineering iii THIS PAGE INTENTIONALLY LEFT BLANK iv ABSTRACT The purpose of this thesis is to streamline the sample preparation

  18. Streamlining DOD Acquisitions: Balancing Schedule with Complexity

    DTIC Science & Technology

    2006-09-01

    from them has a distinct industrial flavor: streamlined processes, benchmarking, and business models . The requirements generation com- munity led by... model ), and the Department of the Navy assumed program lead. [Stable Program Inputs (-)] By 1984, the program goals included delivery of 913 V-22...they subsequently specified a crew of two. [Stable Program Input (-)] The contractor team won in a “fly-off” solely via modeling and simulation

  19. The role of streamline curvature in sand dune dynamics: evidence from field and wind tunnel measurements

    NASA Astrophysics Data System (ADS)

    Wiggs, Giles F. S.; Livingstone, Ian; Warren, Andrew

    1996-09-01

    Field measurements on an unvegetated, 10 m high barchan dune in Oman are compared with measurements over a 1:200 scale fixed model in a wind tunnel. Both the field and wind tunnel data demonstrate similar patterns of wind and shear velocity over the dune, confirming significant flow deceleration upwind of and at the toe of the dune, acceleration of flow up the windward slope, and deceleration between the crest and brink. This pattern, including the widely reported upwind reduction in shear velocity, reflects observations of previous studies. Such a reduction in shear velocity upwind of the dune should result in a reduction in sand transport and subsequent sand deposition. This is not observed in the field. Wind tunnel modelling using a near-surface pulse-wire probe suggests that the field method of shear velocity derivation is inadequate. The wind tunnel results exhibit no reduction in shear velocity upwind of or at the toe of the dune. Evidence provided by Reynolds stress profiles and turbulence intensities measured in the wind tunnel suggest that this maintenance of upwind shear stress may be a result of concave (unstable) streamline curvature. These additional surface stresses are not recorded by the techniques used in the field measurements. Using the occurrence of streamline curvature as a starting point, a new 2-D model of dune dynamics is deduced. This model relies on the establishment of an equilibrium between windward slope morphology, surface stresses induced by streamline curvature, and streamwise acceleration. Adopting the criteria that concave streamline curvature and streamwise acceleration both increase surface shear stress, whereas convex streamline curvature and deceleration have the opposite effect, the relationships between form and process are investigated in each of three morphologically distinct zones: the upwind interdune and concave toe region of the dune, the convex portion of the windward slope, and the crest-brink region. The applicability of the model is supported by measurements of the rate of sand transport and the change of the dune surface in the field.

  20. Numerical investigation on nonlinear effect and vortex formation of oscillatory flow throughout a short tube in a thermoacoustic Stirling engine

    NASA Astrophysics Data System (ADS)

    Yang, Peng; Chen, Hui; Liu, Yingwen

    2017-06-01

    In this paper, a two-dimensional axisymmetric model of a thermoacoustic Stirling engine with a short tube where the cross section narrows has been developed. The transient streamlines and vortex formation through short tubes with different diameters in oscillatory flow have been investigated visually by computational fluid dynamics. Three dimensionless parameters, Reynolds number (Re), Keulegan-Carpenter number (KC), and Womersley number (Wo), are used to describe the flow regime and vortex characteristic throughout the short tube. High Re and Wo numbers indicate that the oscillatory flow develops into the turbulent flow through the short tube. The KC number has a direct effect on the transition of streamlines and the development of the vortex. For a small cross section where KC ≈ 1, streamlines rotate and the vortex forms at both sides of the short tube. The vortex stays in the main flow region, and intensity varies as streamlines are convected downstream. The velocity along the radius presents a Poiseuille profile within the influence of the vortex. For a large cross section where KC < 1, streamlines pass the short tube with little rotation and the vortex disappears in the main flow region and confines near the short tube. The velocity profile tends to be flat. The nonlinear effects including instantaneous pressure drop and power dissipation throughout the short tube are also discussed. It shows that the time averaged pressure drop is generated at the cost of power dissipation. Finally, the "effectiveness" is applied to evaluate the performance of the short tube. The results suggest that increasing the diameter of the short tube is in favor of reducing power dissipation, which is beneficial to improve "effectiveness."

  1. AxTract: Toward microstructure informed tractography.

    PubMed

    Girard, Gabriel; Daducci, Alessandro; Petit, Laurent; Thiran, Jean-Philippe; Whittingstall, Kevin; Deriche, Rachid; Wassermann, Demian; Descoteaux, Maxime

    2017-11-01

    Diffusion-weighted (DW) magnetic resonance imaging (MRI) tractography has become the tool of choice to probe the human brain's white matter in vivo. However, tractography algorithms produce a large number of erroneous streamlines (false positives), largely due to complex ambiguous tissue configurations. Moreover, the relationship between the resulting streamlines and the underlying white matter microstructure characteristics remains poorly understood. In this work, we introduce a new approach to simultaneously reconstruct white matter fascicles and characterize the apparent distribution of axon diameters within fascicles. To achieve this, our method, AxTract, takes full advantage of the recent development DW-MRI microstructure acquisition, modeling, and reconstruction techniques. This enables AxTract to separate parallel fascicles with different microstructure characteristics, hence reducing ambiguities in areas of complex tissue configuration. We report a decrease in the incidence of erroneous streamlines compared to the conventional deterministic tractography algorithms on simulated data. We also report an average increase in streamline density over 15 known fascicles of the 34 healthy subjects. Our results suggest that microstructure information improves tractography in crossing areas of the white matter. Moreover, AxTract provides additional microstructure information along the fascicle that can be studied alongside other streamline-based indices. Overall, AxTract provides the means to distinguish and follow white matter fascicles using their microstructure characteristics, bringing new insights into the white matter organization. This is a step forward in microstructure informed tractography, paving the way to a new generation of algorithms able to deal with intricate configurations of white matter fibers and providing quantitative brain connectivity analysis. Hum Brain Mapp 38:5485-5500, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  2. Impingement of Droplets in 60 Deg Elbows with Potential Flow

    NASA Technical Reports Server (NTRS)

    Hacker, Paul T.; Saper, Paul G.; Kadow, Charles F.

    1956-01-01

    Trajectories were determined for water droplets or other aerosol particles in air flowing through 600 elbows especially designed for two-dimensional potential motion. The elbows were established by selecting as walls of each elbow two streamlines of a flow field produced by a complex potential function that establishes a two-dimensional flow around. a 600 bend. An unlimited number of elbows with slightly different shapes can be established by selecting different pairs of streamlines as walls. Some of these have a pocket on the outside wall. The elbows produced by the complex potential function are suitable for use in aircraft air-inlet ducts and have the following characteristics: (1) The resultant velocity at any point inside the elbow is always greater than zero but never exceeds the velocity at the entrance. (2) The air flow field at the entrance and exit is almost uniform and rectilinear. (3) The elbows are symmetrical with respect to the bisector of the angle of bend. These elbows should have lower pressure losses than bends of constant cross-sectional area. The droplet impingement data derived from the trajectories are presented along with equations so that collection efficiency, area, rate, and distribution of droplet impingement can be determined for any elbow defined by any pair of streamlines within a portion of the flow field established by the complex potential function. Coordinates for some typical streamlines of the flow field and velocity components for several points along these streamlines are presented in tabular form. A comparison of the 600 elbow with previous calculations for a comparable 90 elbow indicated that the impingement characteristics of the two elbows were very similar.

  3. Effect of curvature on stationary crossflow instability of a three-dimensional boundary layer

    NASA Technical Reports Server (NTRS)

    Lin, Ray-Sing; Reed, Helen L.

    1993-01-01

    An incompressible three-dimensional laminar boundary-layer flow over a swept wing is used as a model to study both the wall-curvature and streamline-curvature effects on the stationary crossflow instability. The basic state is obtained by solving the full Navier-Stokes (N-S) equations numerically. The linear disturbance equations are cast on a fixed, body-intrinsic, curvilinear coordinate system. Those nonparallel terms which contribute mainly to the streamline-curvature effect are retained in the formulation of the disturbance equations and approximated by their local finite difference values. The resulting eigenvalue problem is solved by a Chebyshev collocation method. The present results indicate that the convex wall curvature has a stabilizing effect, whereas the streamline curvature has a destabilizing effect. A validation of these effects with an N-S solution for the linear disturbance flow is provided.

  4. Just-In-Time Inventory Management; Application and Recommendations for Naval Hospital, Oakland.

    DTIC Science & Technology

    1992-12-01

    108 c. Break Bulk on Stored Material .................. 110 d. Emphasize Continuous Quality Improvement ...... 111 4. Streamline Order Processing for...manpower. 4. Use of existing industry automation to expedite order processing to the prime vendor. The intent of this research is to present the JIT...34* Collection of baseline data. "* Break bulk on stored material. 85 • Emphasize continuous quality improvement. 4. Streamline order processing for PV

  5. Pharmaceutical marketing in a new age. Effective campaigns still need to focus on what customers want.

    PubMed

    Rao, Sanjay K

    2002-01-01

    The pharmaceutical industry has focused heavily on marketers' ability to market new products more efficiently. However, a more streamlined marketing approach can help address customers' needs and ease the pressure on drug companies to discover new drugs with blockbuster appeal. Through discussion and a detailed example, this article describes a stream-lined approach to creating more effective marketing and sales force strategies.

  6. Multiple Employment Training Programs. Major Overhaul Needed To Reduce Costs, Streamline the Bureaucracy, and Improve Results. Testimony before the Committee on Labor and Human Resources. U.S. Senate.

    ERIC Educational Resources Information Center

    Crawford, Clarence C.

    Research conducted by the General Accounting Office (GAO) indicates that the current system of multiple employment training programs requires major overhaul to reduce costs, streamline the bureaucracy, and improve results. The current system of 163 different federal employment training programs wastes resources and confuses and frustrates clients,…

  7. Basal streamline sprays for hardwood resprout control: herbicides, concentrations, and streaks per stem

    Treesearch

    James H. Miller

    1997-01-01

    Basal streamline sprays were tested to control sweetgum, water oak, and southern red oak that ranged from 0.5 to 2 inches groundline diameter. Primary test herbicides and mixtures were triclopyr (Garlon 4) at 20 and 40 percent mixed with 10 percent d-limonene (Cide-Kick) and the remainder diesel; and imazapyr (Chopper) at 5 and 10 percent mixed in only diesel. Primary...

  8. 24 CFR 903.11 - Are certain PHAs eligible to submit a streamlined Annual Plan?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... streamlined Annual Plan must include the information required by § 903.7(a), (b), (c), (d), (g), (h), (k), (m), (n), (o), (p) and (r). The information required by § 903.7(m) must be included only to the extent... § 903.7(a), (b), (c), (d), (e), (f), (k), (l), (o), (p) and (r). [65 FR 49484, Aug. 14, 2000, as amended...

  9. Shear-modulated electroosmotic flow on a patterned charged surface.

    PubMed

    Wei, Hsien-Hung

    2005-04-15

    The effect of imposing shear flow on a charge-modulated electroosmotic flow is theoretically investigated. The flow structures exhibit either saddle points or closed streamlines, depending on the relative strength of an imposed shear to the applied electric field. The formation of closed streamlines could be advantageous for trapping nondiffusive particles at desired locations. Different time periodic alternating flows and their corresponding particle trajectories are also examined to assess strategies for creating efficient mixing.

  10. Predictive wall adjustment strategy for two-dimensional flexible walled adaptive wind tunnel: A detailed description of the first one-step method

    NASA Technical Reports Server (NTRS)

    Wolf, Stephen W. D.; Goodyer, Michael J.

    1988-01-01

    Following the realization that a simple iterative strategy for bringing the flexible walls of two-dimensional test sections to streamline contours was too slow for practical use, Judd proposed, developed, and placed into service what was the first Predictive Strategy. The Predictive Strategy reduced by 75 percent or more the number of iterations of wall shapes, and therefore the tunnel run-time overhead attributable to the streamlining process, required to reach satisfactory streamlines. The procedures of the Strategy are embodied in the FORTRAN subroutine WAS (standing for Wall Adjustment Strategy) which is written in general form. The essentials of the test section hardware, followed by the underlying aerodynamic theory which forms the basis of the Strategy, are briefly described. The subroutine is then presented as the Appendix, broken down into segments with descriptions of the numerical operations underway in each, with definitions of variables.

  11. The development of a self-streamlining flexible walled transonic test section

    NASA Technical Reports Server (NTRS)

    Goodyer, M. J.; Wolf, S. W. D.

    1980-01-01

    This design eliminates the uncertainties in data from conventional transonic test sections. Sidewalls are rigid, and the flexible floor and ceiling are positioned by motorized jacks controlled by on-line computer to minimize run times. The tunnel-computer combination is self-streamlining without reference to the model. Data is taken from the model only when the walls are good streamlines, and is corrected for the small, known but inevitable residual interferences. Two-dimensional validation testing in the Mach range up to about 0.85 where the walls are just supercritical shows good agreement with reference data using a height:chord ratio of 1.5. Techniques are under development to extend Mach number above 1. This work has demonstrated the feasibility of almost eliminating wall interferences, improving flow quality, and reducing power requirements or increasing Reynolds number. Extensions to three-dimensional testing are outlined.

  12. Model Communities Hint at Promiscuous Metabolic Linkages between Ubiquitous Free-Living Freshwater Bacteria

    PubMed Central

    Buck, Moritz; Hamilton, Joshua J.; Wurzbacher, Christian; Grossart, Hans-Peter; Eiler, Alexander

    2018-01-01

    ABSTRACT Genome streamlining is frequently observed in free-living aquatic microorganisms and results in physiological dependencies between microorganisms. However, we know little about the specificity of these microbial associations. In order to examine the specificity and extent of these associations, we established mixed cultures from three different freshwater environments and analyzed the cooccurrence of organisms using a metagenomic time series. Free-living microorganisms with streamlined genomes lacking multiple biosynthetic pathways showed no clear recurring pattern in their interaction partners. Free-living freshwater bacteria form promiscuous cooperative associations. This notion contrasts with the well-documented high specificities of interaction partners in host-associated bacteria. Considering all data together, we suggest that highly abundant free-living bacterial lineages are functionally versatile in their interactions despite their distinct streamlining tendencies at the single-cell level. This metabolic versatility facilitates interactions with a variable set of community members. PMID:29848762

  13. An Integrated Approach to Characterizing Bypassed Oil in Heterogeneous and Fractured Reservoirs Using Partitioning Tracers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Akhil Datta-Gupta

    2006-12-31

    We explore the use of efficient streamline-based simulation approaches for modeling partitioning interwell tracer tests in hydrocarbon reservoirs. Specifically, we utilize the unique features of streamline models to develop an efficient approach for interpretation and history matching of field tracer response. A critical aspect here is the underdetermined and highly ill-posed nature of the associated inverse problems. We have investigated the relative merits of the traditional history matching ('amplitude inversion') and a novel travel time inversion in terms of robustness of the method and convergence behavior of the solution. We show that the traditional amplitude inversion is orders of magnitudemore » more non-linear and the solution here is likely to get trapped in local minimum, leading to inadequate history match. The proposed travel time inversion is shown to be extremely efficient and robust for practical field applications. The streamline approach is generalized to model water injection in naturally fractured reservoirs through the use of a dual media approach. The fractures and matrix are treated as separate continua that are connected through a transfer function, as in conventional finite difference simulators for modeling fractured systems. A detailed comparison with a commercial finite difference simulator shows very good agreement. Furthermore, an examination of the scaling behavior of the computation time indicates that the streamline approach is likely to result in significant savings for large-scale field applications. We also propose a novel approach to history matching finite-difference models that combines the advantage of the streamline models with the versatility of finite-difference simulation. In our approach, we utilize the streamline-derived sensitivities to facilitate history matching during finite-difference simulation. The use of finite-difference model allows us to account for detailed process physics and compressibility effects. The approach is very fast and avoids much of the subjective judgments and time-consuming trial-and-errors associated with manual history matching. We demonstrate the power and utility of our approach using a synthetic example and two field examples. We have also explored the use of a finite difference reservoir simulator, UTCHEM, for field-scale design and optimization of partitioning interwell tracer tests. The finite-difference model allows us to include detailed physics associated with reactive tracer transport, particularly those related with transverse and cross-streamline mechanisms. We have investigated the potential use of downhole tracer samplers and also the use of natural tracers for the design of partitioning tracer tests. Finally, we discuss several alternative ways of using partitioning interwell tracer tests (PITTs) in oil fields for the calculation of oil saturation, swept pore volume and sweep efficiency, and assess the accuracy of such tests under a variety of reservoir conditions.« less

  14. Erosional origin of drumlins and megaridges

    NASA Astrophysics Data System (ADS)

    Eyles, Nick; Putkinen, Niko; Sookhan, Shane; Arbelaez-Moreno, Lina

    2016-06-01

    The erodent layer hypothesis (ELH) proposes that drumlinization leaves no substantial stratigraphic record because it is primarily an erosional process that cuts an unconformity across pre-existing bed materials. Drumlins most commonly have autochthonous cores of antecedent till(s), other stiff and coarse-grained sediment and rock or any combination thereof, and are also found closely juxtaposed with rock drumlins within the same flow sets ('mixed beds'). This is at odds with the suggested growth of drumlins by vertical accretion ('emergence') from deforming subglacial till ('soft beds'). ELH argues that drumlins 'grow down' by erosional carving of pre-existing stiff till, sediment and/or rock by a thin (< 1 m) layer of deforming subglacial debris which abrades its substrate. This process is well known to the science of tribology (the study of wearing surfaces) where remnant micro-drumlins, ridges and grooves comparable to drumlins and megaridges are cut by debris ('erodent layers') between surfaces in relative motion. In the subglacial setting the erodent layer comprises deforming diamict containing harder 'erodents' such as boulders, clast-rich zones or frozen rafts. Similar, till-like erodent layers (cataclasites) cut streamlined surfaces below gravity-driven mass flows such as rock avalanches, landslides and slumps, pyroclastic flows and debris flows; streamlined surfaces including drumlin-like 'ellipsoidal bumps' and ridges are also common on the surfaces of faults. Megadrumlins, drumlins and megaridges comprise an erosional continuum in many flow sets. This records the progressive dissection of large streamlined bedforms to form successively more elongate daughter drumlins and megaridges ('clones') as the bed is lowered to create a low-slip surface that allows fast ice flow and ice streaming. Clones are the 'missing links' in the continuum. ELH predicts preservation within drumlins of antecedent remnant tills and stratigraphies deposited earlier in the glacial cycle under sluggish or steady-state ice flows that were then streamlined by erosion under streaming ice flows. The erodent layer may be preserved as a relatively thin, loosely-consolidated surficial till that drapes the streamlined bedform (the 'upper till', 'cap till', 'till veneer', 'till mantle', 'retreat till', or 'englacial debris' of many previous reports). ELH suggests that there is a fundamental commonality of all forms of erosional wear and streamlining on sliding interfaces from the microscopic scale to the macroscopic scale of ice sheet beds.

  15. Formation of turbulence around flow singularities

    NASA Technical Reports Server (NTRS)

    Zak, M.

    1983-01-01

    The formation of turbulence around singular points of a flow such as stagnation points, tangential jumps of velocity, are analyzed. It is proved that turbulence is inevitably generated by the rear stagnation point, but cannot be generated by the nose stagnation point of a streamlined body. Special attention is paid to an evolution of turbulence induced by a tangential jump of velocity. A qualitative analysis of a turbulent flow between two rotating concentric cylinders and around a streamlined cylinder is given.

  16. Shear-Modulated Electroosmotic Flow on a Patterned Charged Surface

    NASA Astrophysics Data System (ADS)

    Wei, Hsien-Hung

    2004-11-01

    The effect of imposing shear flow on a charge-modulated electroosmotic flow is theoretically investigated. The flow pattern can contain saddle points or closed streamlines, depending on the relative strength of an imposed shear to the applied electrical field. The formation of closed streamlines could be advantageous for trapping non-diffusive particles in desired locations. Different time periodic alternating flows and their corresponding particle trajectories are also examined for assessing strategies for creating efficient mixing.

  17. "Was Lietz padagogisch erstrebte, hat Hitler politisch durchgesetzt". Schulreformerische Traditionen und nationalsozialistische Schulpolitik in Thuringen" ("The Pedagogical Intentions of Lietz Were Enforced Politically by Hitler". Traditions of School Reform and National Socialist School Policy in Thuringia).

    ERIC Educational Resources Information Center

    Lesanovsky, Werner

    1998-01-01

    Inquires of the regional effects of National Socialist school policy, using as an example Thuringia (Germany), the educational landscape of which is traditionally characterized by reform-oriented institutions. Reveals how streamlining of reform schools and instruction from the top and self-streamlining from the bottom ran parallel after 1933. (CMK)

  18. Transonic streamline of symmetric wing under the influence unilateral oscillations characterized by the spectrum of two frequencies

    NASA Astrophysics Data System (ADS)

    Zamuraev, V. P.; Kalinina, A. P.

    2017-10-01

    Forced high-frequency vibrations of the airfoil surface part with the amplitude almost equal to the sound velocity can change significantly the lift force of the symmetric profile streamlined at zero angle of attack. The oscillation consists of two harmonics. The ratio of harmonics frequencies values is equal to 2. The present work shows that the aerodynamic properties depend significantly on the specific energy contribution of each frequency.

  19. Streamlined Livestock Trailer

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Bull Nose livestock trailer, manufactured by American Trailer, Inc. is one of a line of highway transport vehicles manufactured by American Trailers, Inc. The slant side front end is a streamlining feature based on a NASA Research Program which investigated the aerodynamic characteristics of trailer/tractor combinations and suggested ways of reducing air resistance. Application of NASA's aerodynamic research technology to the bull nose design resulted in a 10 percent reduction in air drag, which translates into annual fuel savings of several hundred dollars.

  20. A novel framework for the local extraction of extra-axial cerebrospinal fluid from MR brain images

    NASA Astrophysics Data System (ADS)

    Mostapha, Mahmoud; Shen, Mark D.; Kim, SunHyung; Swanson, Meghan; Collins, D. Louis; Fonov, Vladimir; Gerig, Guido; Piven, Joseph; Styner, Martin A.

    2018-03-01

    The quantification of cerebrospinal fluid (CSF) in the human brain has shown to play an important role in early postnatal brain developmental. Extr a-axial fluid (EA-CSF), which is characterized by the CSF in the subarachnoid space, is promising in the early detection of children at risk for neurodevelopmental disorders. Currently, though, there is no tool to extract local EA-CSF measurements in a way that is suitable for localized analysis. In this paper, we propose a novel framework for the localized, cortical surface based analysis of EA-CSF. In our proposed processing, we combine probabilistic brain tissue segmentation, cortical surface reconstruction as well as streamline based local EA-CSF quantification. For streamline computation, we employ the vector field generated by solving a Laplacian partial differential equation (PDE) between the cortical surface and the outer CSF hull. To achieve sub-voxel accuracy while minimizing numerical errors, fourth-order Runge-Kutta (RK4) integration was used to generate the streamlines. Finally, the local EA-CSF is computed by integrating the CSF probability along the generated streamlines. The proposed local EA-CSF extraction tool was used to study the early postnatal brain development in typically developing infants. The results show that the proposed localized EA-CSF extraction pipeline can produce statistically significant regions that are not observed in previous global approach.

  1. Method based on the Laplace equations to reconstruct the river terrain for two-dimensional hydrodynamic numerical modeling

    NASA Astrophysics Data System (ADS)

    Lai, Ruixun; Wang, Min; Yang, Ming; Zhang, Chao

    2018-02-01

    The accuracy of the widely-used two-dimensional hydrodynamic numerical model depends on the quality of the river terrain model, particularly in the main channel. However, in most cases, the bathymetry of the river channel is difficult or expensive to obtain in the field, and there is a lack of available data to describe the geometry of the river channel. We introduce a method that originates from the grid generation with the elliptic equation to generate streamlines of the river channel. The streamlines are numerically solved with the Laplace equations. In the process, streamlines in the physical domain are first computed in a computational domain, and then transformed back to the physical domain. The interpolated streamlines are integrated with the surrounding topography to reconstruct the entire river terrain model. The approach was applied to a meandering reach in the Qinhe River, which is a tributary in the middle of the Yellow River, China. Cross-sectional validation and the two-dimensional shallow-water equations are used to test the performance of the river terrain generated. The results show that the approach can reconstruct the river terrain using the data from measured cross-sections. Furthermore, the created river terrain can maintain a geometrical shape consistent with the measurements, while generating a smooth main channel. Finally, several limitations and opportunities for future research are discussed.

  2. Evolution of supersonic corner vortex in a hypersonic inlet/isolator model

    NASA Astrophysics Data System (ADS)

    Huang, He-Xia; Tan, Hui-Jun; Sun, Shu; Ling, Yu

    2016-12-01

    There are complex corner vortex flows in a rectangular hypersonic inlet/isolator. The corner vortex propagates downstream and interacts with the shocks and expansion waves in the isolator repeatedly. The supersonic corner vortex in a generic hypersonic inlet/isolator model is theoretically and numerically analyzed at a freestream Mach number of 4.92. The cross-flow topology of the corner vortex flow is found to obey Zhang's theory ["Analytical analysis of subsonic and supersonic vortex formation," Acta Aerodyn. Sin. 13, 259-264 (1995)] strictly, except for the short process with the vortex core situated in a subsonic flow which is surrounded by a supersonic flow. In general, the evolution history of the corner vortex under the influence of the background waves in the hypersonic inlet/isolator model can be classified into two types, namely, from the adverse pressure gradient region to the favorable pressure gradient region and the reversed one. For type 1, the corner vortex is a one-celled vortex with the cross-sectional streamlines spiraling inwards at first. Then the Hopf bifurcation occurs and the streamlines in the outer part of the limit cycle switch to spiraling outwards, yielding a two-celled vortex. The limit cycle shrinks gradually and finally vanishes with the streamlines of the entire corner vortex spiraling outwards. For type 2, the cross-sectional streamlines of the corner vortex spiral outwards first. Then a stable limit cycle is formed, yielding a two-celled vortex. The short-lived limit cycle forces the streamlines in the corner vortex to change the spiraling trends rapidly. Although it is found in this paper that there are some defects on the theoretical proof of the limit cycle, Zhang's theory is proven useful for the prediction and qualitative analysis of the complex corner vortex in a hypersonic inlet/isolator. In addition, three conservation laws inside the limit cycle are obtained.

  3. Reduced Structural Connectivity in Frontostriatal White Matter Tracts in the Associative Loop in Schizophrenia.

    PubMed

    Levitt, James J; Nestor, Paul G; Levin, Laura; Pelavin, Paula; Lin, Pan; Kubicki, Marek; McCarley, Robert W; Shenton, Martha E; Rathi, Yogesh

    2017-11-01

    The striatum receives segregated and integrative white matter tracts from the cortex facilitating information processing in the cortico-basal ganglia network. The authors examined both types of input tracts in the striatal associative loop in chronic schizophrenia patients and healthy control subjects. Structural and diffusion MRI scans were acquired on a 3-T system from 26 chronic schizophrenia patients and 26 matched healthy control subjects. Using FreeSurfer, the associative cortex was parcellated into ventrolateral prefrontal cortex and dorsolateral prefrontal cortex subregions. The striatum was manually parcellated into its associative and sensorimotor functional subregions. Fractional anisotropy and normalized streamlines, an estimate of fiber counts, were assessed in four frontostriatal tracts (dorsolateral prefrontal cortex-associative striatum, dorsolateral prefrontal cortex-sensorimotor striatum, ventrolateral prefrontal cortex-associative striatum, and ventrolateral prefrontal cortex-sensorimotor striatum). Furthermore, these measures were correlated with a measure of cognitive control, the Trail-Making Test, Part B. Results showed reduced fractional anisotropy and fewer streamlines in chronic schizophrenia patients for all four tracts, both segregated and integrative. Post hoc t tests showed reduced fractional anisotropy in the left ventrolateral prefrontal cortex-associative striatum and left ventrolateral prefrontal cortex-sensorimotor striatum and fewer normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum and in the left and right ventrolateral prefrontal cortex-sensorimotor striatum in chronic schizophrenia patients. Furthermore, normalized streamlines in the right dorsolateral prefrontal cortex-sensorimotor striatum negatively correlated with Trail-Making Test, Part B, time spent in healthy control subjects but not in chronic schizophrenia patients. These findings demonstrated that structural connectivity is reduced in both segregated and integrative tracts in the striatal associative loop in chronic schizophrenia and that reduced normalized streamlines in the right-hemisphere dorsolateral prefrontal cortex-sensorimotor striatum predicted worse cognitive control in healthy control subjects but not in chronic schizophrenia patients, suggesting a loss of a "normal" brain-behavior correlation in chronic schizophrenia.

  4. Intelligence and Electronic Warfare (IEW) Streamlining Project. Volume 1. Sustainment Analysis Report. Revision

    DTIC Science & Technology

    1992-10-30

    I Sustainment Analysis Report Accesion For NTIS CRA&I DTIC 1 AP- U. an-;o u,ced [] jj ~~~Y INSPECTED 5 Js~~~o By.......... ............ Dit Ib ’tiot...ELECTRONIC WARFARE (1EW) STREAMUNING PROJECT Vohune I Sustainment Analysis Report Revised October 30, 1992 93-29047 The views, opinions, and findings...Streamlining Project, C OPM-91-2964 Volume I, Sustainment Analysis Report PR 02TO2K 6. AUTHORIS) David P. Nicholas, Robert E. Klebo. Wolodymyr J. Mokey

  5. Local-Rapid Evaluation of Atmospheric Conditions (L-REAC (trademark)) System, Design and Development. Volume 3. (Operational L-REAC (trademark))

    DTIC Science & Technology

    2011-09-01

    tunnel results show the airflow pattern around a single building. Streamline flow is from left to right. The “canyon flow” is not shown. (Snyder...Agency (EPA)/National Oceanic and Atmospheric Administration (NOAA) wind tunnel results by sampling atmospheric data at strategic locations around a...NOAA wind tunnel results show the airflow pattern around a single building. Streamline flow is from left to right. The “canyon flow” is not shown

  6. Control of Heat Fluxes on the Surface of the Body Streamlined by Supersonic Flow with the Help of MHD Method

    DTIC Science & Technology

    2008-10-01

    Supersonic Flow with the Help of MHD Method 5a. CONTRACT NUMBER ISTC Registration No: 3475 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S) ISTC 05-7004 12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release...Center ( ISTC ), Moscow. ISTC Project No. 3475р Control of heat fluxes on the surface of the body streamlined by supersonic flow with the help of MHD

  7. Streamline-based microfluidic device

    NASA Technical Reports Server (NTRS)

    Tai, Yu-Chong (Inventor); Zheng, Siyang (Inventor); Kasdan, Harvey (Inventor)

    2013-01-01

    The present invention provides a streamline-based device and a method for using the device for continuous separation of particles including cells in biological fluids. The device includes a main microchannel and an array of side microchannels disposed on a substrate. The main microchannel has a plurality of stagnation points with a predetermined geometric design, for example, each of the stagnation points has a predetermined distance from the upstream edge of each of the side microchannels. The particles are separated and collected in the side microchannels.

  8. Improving patient access and streamlining processes through enterprise intelligence systems.

    PubMed

    Dunn, Ronald L

    2014-01-01

    This article demonstrates how enterprise intelligence systems can be used to improve operational efficiency in hospitals. Enterprise intelligence systems mine raw data from disparate systems and transform the data into actionable information, which when used appropriately, support streamlined processes, optimize resources, and positively affect staff efficiency and the quality of patient care. Case studies on the implementation of McKesson Performance Visibility and Capacity Planner enterprise intelligence solutions at the Southlake Regional Health Centre and Lions Gate and Richmond Hospitals are provided.

  9. A tale of three Brownfields

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sweet, F.R.; Worthington, M.A.; Belli, E.

    Contaminated site remediation and reuse, or Brownfield redevelopment, has become an increasingly important approach to site development in the northeast corridor, yet the scale of this activity is but a fraction of its full potential. The problem lies in the multi-jurisdictional quagmire that confronts a Brownfield project. Permitting such projects is an overly taxing dynamic process that has become a staple diet for adept multidisciplinary consulting firms. Limited government sanctions such as clean sites initiatives and economic revitalization zones are at best, when successful, interesting bench studies. The central hypothesis that, if regulations are streamlined then site reuse will occur,more » is sound. Yet streamlining brings concerns that the protection of public health and the environment will be compromised and that the result will be a lower standard of public protection for urban populations. The authors postulate that the permitting of Brownfield projects can be streamlined without creating a double standard of risk tolerance. The authors present evidence of this by comparing publicly and privately funded projects.« less

  10. Analysis of Jupiter's Oval BA: A Streamlined Approach

    NASA Technical Reports Server (NTRS)

    Sussman, Michael G.; Chanover, Nancy J.; Simon-Miller, Amy A.; Vasavada, Ashwin R.; Beebe, Reta F.

    2010-01-01

    We present a novel method of constructing streamlines to derive wind speeds within jovian vortices and demonstrate its application to Oval BA for 2001 pre-reddened Cassini flyby data, 2007 post-reddened New Horizons flyby data, and 1998 Galileo data of precursor Oval DE. Our method, while automated, attempts to combine the advantages of both automated and manual cloud tracking methods. The southern maximum wind speed of Oval BA does not show significant changes between these data sets to within our measurement uncertainty. The northern maximum dries appear to have increased in strength during this time interval, tvhich likely correlates with the oval's return to a symmetric shape. We demonstrate how the use of closed streamlines can provide measurements of vorticity averaged over the encircled area with no a priori assumptions concerning oval shape. We find increased averaged interior vorticity between pre- and post-reddened Oval BA, with the precursor Oval DE occupying a middle value of vorticity between these two.

  11. Numerical analysis of eccentric orifice plate using ANSYS Fluent software

    NASA Astrophysics Data System (ADS)

    Zahariea, D.

    2016-11-01

    In this paper the eccentric orifice plate is qualitative analysed as compared with the classical concentric orifice plate from the point of view of sedimentation tendency of solid particles in the fluid whose flow rate is measured. For this purpose, the numerical streamlines pattern will be compared for both orifice plates. The numerical analysis has been performed using ANSYS Fluent software. The methodology of CFD analysis is presented: creating the 3D solid model, fluid domain extraction, meshing, boundary condition, turbulence model, solving algorithm, convergence criterion, results and validation. Analysing the numerical streamlines, for the concentric orifice plate can be clearly observed two circumferential regions of separated flows, upstream and downstream of the orifice plate. The bottom part of these regions are the place where the solid particles could sediment. On the other hand, for the eccentric orifice plate, the streamlines pattern suggest that no sedimentation will occur because at the bottom area of the pipe there are no separated flows.

  12. An experimental study of a self-confined flow with ring-vorticity distribution. Ph.D. Thesis. Final Report

    NASA Technical Reports Server (NTRS)

    Lin, K. M.; Moore, F. K.

    1976-01-01

    A new form of self-confined flow was investigated in which a recirculation zone forms away from any solid boundary. An inviscid flow analysis indicated that in a purely meridional axisymmetric flow a stationary, spherical, self-confined region should occur in the center of a streamlined divergent-convergent enlargement zone. The spherical confinement region would be at rest and at constant pressure. Experimental investigations were carried out in a specially built test apparatus to establish the desired confined flow. The streamlined divergent-convergent interior shape of the test section was fabricated according to the theoretical calculation for a particular streamline. The required inlet vorticity distribution was generated by producing a velocity profile with a shaped gauze screen in the straight pipe upstream of the test section. Fluid speed and turbulence intensity were measured with a constant-temperature hot-wire anemometer system. The measured results indicated a very orderly and stable flow field.

  13. Streamlining Collaborative Planning in Spacecraft Mission Architectures

    NASA Technical Reports Server (NTRS)

    Misra, Dhariti; Bopf, Michel; Fishman, Mark; Jones, Jeremy; Kerbel, Uri; Pell, Vince

    2000-01-01

    During the past two decades, the planning and scheduling community has substantially increased the capability and efficiency of individual planning and scheduling systems. Relatively recently, research work to streamline collaboration between planning systems is gaining attention. Spacecraft missions stand to benefit substantially from this work as they require the coordination of multiple planning organizations and planning systems. Up to the present time this coordination has demanded a great deal of human intervention and/or extensive custom software development efforts. This problem will become acute with increased requirements for cross-mission plan coordination and multi -spacecraft mission planning. The Advanced Architectures and Automation Branch of NASA's Goddard Space Flight Center is taking innovative steps to define collaborative planning architectures, and to identify coordinated planning tools for Cross-Mission Campaigns. Prototypes are being developed to validate these architectures and assess the usefulness of the coordination tools by the planning community. This presentation will focus on one such planning coordination too], named Visual Observation Layout Tool (VOLT), which is currently being developed to streamline the coordination between astronomical missions

  14. Regimes of Flow over Complex Structures of Endothelial Glycocalyx: A Molecular Dynamics Simulation Study.

    PubMed

    Jiang, Xi Zhuo; Feng, Muye; Ventikos, Yiannis; Luo, Kai H

    2018-04-10

    Flow patterns on surfaces grafted with complex structures play a pivotal role in many engineering and biomedical applications. In this research, large-scale molecular dynamics (MD) simulations are conducted to study the flow over complex surface structures of an endothelial glycocalyx layer. A detailed structure of glycocalyx has been adopted and the flow/glycocalyx system comprises about 5,800,000 atoms. Four cases involving varying external forces and modified glycocalyx configurations are constructed to reveal intricate fluid behaviour. Flow profiles including temporal evolutions and spatial distributions of velocity are illustrated. Moreover, streamline length and vorticity distributions under the four scenarios are compared and discussed to elucidate the effects of external forces and glycocalyx configurations on flow patterns. Results show that sugar chain configurations affect streamline length distributions but their impact on vorticity distributions is statistically insignificant, whilst the influence of the external forces on both streamline length and vorticity distributions are trivial. Finally, a regime diagram for flow over complex surface structures is proposed to categorise flow patterns.

  15. A new compression format for fiber tracking datasets.

    PubMed

    Presseau, Caroline; Jodoin, Pierre-Marc; Houde, Jean-Christophe; Descoteaux, Maxime

    2015-04-01

    A single diffusion MRI streamline fiber tracking dataset may contain hundreds of thousands, and often millions of streamlines and can take up to several gigabytes of memory. This amount of data is not only heavy to compute, but also difficult to visualize and hard to store on disk (especially when dealing with a collection of brains). These problems call for a fiber-specific compression format that simplifies its manipulation. As of today, no fiber compression format has yet been adopted and the need for it is now becoming an issue for future connectomics research. In this work, we propose a new compression format, .zfib, for streamline tractography datasets reconstructed from diffusion magnetic resonance imaging (dMRI). Tracts contain a large amount of redundant information and are relatively smooth. Hence, they are highly compressible. The proposed method is a processing pipeline containing a linearization, a quantization and an encoding step. Our pipeline is tested and validated under a wide range of DTI and HARDI tractography configurations (step size, streamline number, deterministic and probabilistic tracking) and compression options. Similar to JPEG, the user has one parameter to select: a worst-case maximum tolerance error in millimeter (mm). Overall, we find a compression factor of more than 96% for a maximum error of 0.1mm without any perceptual change or change of diffusion statistics (mean fractional anisotropy and mean diffusivity) along bundles. This opens new opportunities for connectomics and tractometry applications. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. Automated electric valve for electrokinetic separation in a networked microfluidic chip.

    PubMed

    Cui, Huanchun; Huang, Zheng; Dutta, Prashanta; Ivory, Cornelius F

    2007-02-15

    This paper describes an automated electric valve system designed to reduce dispersion and sample loss into a side channel when an electrokinetically mobilized concentration zone passes a T-junction in a networked microfluidic chip. One way to reduce dispersion is to control current streamlines since charged species are driven along them in the absence of electroosmotic flow. Computer simulations demonstrate that dispersion and sample loss can be reduced by applying a constant additional electric field in the side channel to straighten current streamlines in linear electrokinetic flow (zone electrophoresis). This additional electric field was provided by a pair of platinum microelectrodes integrated into the chip in the vicinity of the T-junction. Both simulations and experiments of this electric valve with constant valve voltages were shown to provide unsatisfactory valve performance during nonlinear electrophoresis (isotachophoresis). On the basis of these results, however, an automated electric valve system was developed with improved valve performance. Experiments conducted with this system showed decreased dispersion and increased reproducibility as protein zones isotachophoretically passed the T-junction. Simulations of the automated electric valve offer further support that the desired shape of current streamlines was maintained at the T-junction during isotachophoresis. Valve performance was evaluated at different valve currents based on statistical variance due to dispersion. With the automated control system, two integrated microelectrodes provide an effective way to manipulate current streamlines, thus acting as an electric valve for charged species in electrokinetic separations.

  17. Theoretical Calculations on Sediment Transport on Titan, and the Possible Production of Streamlined Forms

    NASA Technical Reports Server (NTRS)

    Burr, D. M.; Emery, J. P.; Lorenz, R. D.

    2005-01-01

    The Cassini Imaging Science System (ISS) has been returning images of Titan, along with other Saturnian satellites. Images taken through the 938 nm methane window see down to Titan's surface. One of the purposes of the Cassini mission is to investigate possible fluid cycling on Titan. Lemniscate features shown recently and radar evidence of surface flow prompted us to consider theoretically the creation by methane fluid flow of streamlined forms on Titan. This follows work by other groups in theoretical consideration of fluid motion on Titan's surface.

  18. Numerical Modeling of Three-Dimensional Confined Flows

    NASA Technical Reports Server (NTRS)

    Greywall, M. S.

    1981-01-01

    A three dimensional confined flow model is presented. The flow field is computed by calculating velocity and enthalpy along a set of streamlines. The finite difference equations are obtained by applying conservation principles to streamtubes constructed around the chosen streamlines. With appropriate substitutions for the body force terms, the approach computes three dimensional magnetohydrodynamic channel flows. A listing of a computer code, based on this approach is presented in FORTRAN IV language. The code computes three dimensional compressible viscous flow through a rectangular duct, with the duct cross section specified along the axis.

  19. BootGraph: probabilistic fiber tractography using bootstrap algorithms and graph theory.

    PubMed

    Vorburger, Robert S; Reischauer, Carolin; Boesiger, Peter

    2013-02-01

    Bootstrap methods have recently been introduced to diffusion-weighted magnetic resonance imaging to estimate the measurement uncertainty of ensuing diffusion parameters directly from the acquired data without the necessity to assume a noise model. These methods have been previously combined with deterministic streamline tractography algorithms to allow for the assessment of connection probabilities in the human brain. Thereby, the local noise induced disturbance in the diffusion data is accumulated additively due to the incremental progression of streamline tractography algorithms. Graph based approaches have been proposed to overcome this drawback of streamline techniques. For this reason, the bootstrap method is in the present work incorporated into a graph setup to derive a new probabilistic fiber tractography method, called BootGraph. The acquired data set is thereby converted into a weighted, undirected graph by defining a vertex in each voxel and edges between adjacent vertices. By means of the cone of uncertainty, which is derived using the wild bootstrap, a weight is thereafter assigned to each edge. Two path finding algorithms are subsequently applied to derive connection probabilities. While the first algorithm is based on the shortest path approach, the second algorithm takes all existing paths between two vertices into consideration. Tracking results are compared to an established algorithm based on the bootstrap method in combination with streamline fiber tractography and to another graph based algorithm. The BootGraph shows a very good performance in crossing situations with respect to false negatives and permits incorporating additional constraints, such as a curvature threshold. By inheriting the advantages of the bootstrap method and graph theory, the BootGraph method provides a computationally efficient and flexible probabilistic tractography setup to compute connection probability maps and virtual fiber pathways without the drawbacks of streamline tractography algorithms or the assumption of a noise distribution. Moreover, the BootGraph can be applied to common DTI data sets without further modifications and shows a high repeatability. Thus, it is very well suited for longitudinal studies and meta-studies based on DTI. Copyright © 2012 Elsevier Inc. All rights reserved.

  20. Patient and physician attitudes regarding risk and benefit in streamlined development programmes for antibacterial drugs: a qualitative analysis.

    PubMed

    Holland, Thomas L; Mikita, Stephen; Bloom, Diane; Roberts, Jamie; McCall, Jonathan; Collyar, Deborah; Santiago, Jonas; Tiernan, Rosemary; Toerner, Joseph

    2016-11-10

    To explore patient, caregiver and physician perceptions and attitudes regarding the balance of benefit and risk in using antibacterial drugs developed through streamlined development processes. Semistructured focus groups and in-depth interviews were conducted to elicit perceptions and attitudes about the use of antibacterial drugs to treat multidrug-resistant infections. Participants were given background information about antibiotic resistance, streamlined drug development programmes and FDA drug approval processes. Audio recordings of focus groups/interviews were reviewed and quotes excerpted and categorised to identify key themes. Two primary stakeholder groups were engaged: one comprising caregivers, healthy persons and patients who had recovered from or were at risk of resistant infection (N=67; 11 focus groups); and one comprising physicians who treat resistant infections (N=23). Responses from focus groups/interviews indicated widespread awareness among patients/caregivers and physicians of the seriousness of the problem of antibacterial resistance. Both groups were willing to accept a degree of uncertainty regarding the balance of risk and benefit in a new therapy where a serious unmet need exists, but also expressed a desire for rigorous monitoring and rapid, transparent reporting of safety/effectiveness data. Both groups wanted to ensure that >1 physician had input on whether to treat patients with antibiotics developed through a streamlined process. Some patients/caregivers unfamiliar with exigencies of critical care suggested a relatively large multidisciplinary team, while physicians believed individual expert consultations would be preferable. Both groups agreed that careful oversight and stewardship of antibacterial drugs are needed to ensure patient safety, preserve efficacy and prevent abuse. Groups comprising patients/caregivers and physicians were aware of serious issues posed by resistant infections and the lack of effective antibacterial drug therapies and shared a consensus that streamlined development programmes represent a necessary response to the resistance crisis, but one that requires enhanced safeguards and risk communication. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  1. Stripping Away the Forest; Sweden's Glacially Streamlined Landscape Evaluated through Lidar

    NASA Astrophysics Data System (ADS)

    Dowling, T.; Spagnolo, M.; Moller, P.

    2014-12-01

    The newly available Swedish National Height Model (SNHM) is a 2.0 m horizontal, and 0.1 m vertical resolution digital elevation model (DEM) that is free at the point of use for researchers based at Swedish institutions. With coverage currently at ~80% of the country and due to be completed by 2015 this spatially extensive, high resolution dataset has opened up new avenues of research for Quaternary geology in the country. The work presented here utilises the SNHM to map and evaluate more than 10,000 glacially streamlined landforms in the south-east of Sweden. The subsequently extracted morphological variables of length, width and height are then used to investiagte three areas; to test recent conclusions drawn from the glacially streamlined landscapes of Great Britain and North America/Canada, to assess the impact of different core types on the morphological expression of said features and to attempt to calculate which morphological variable best accounts for the variability seen in the dataset. It is found that in common with drumlins found in the British Isles, and elsewhere, their characteristics can be described by a log-normal distribution. However the long tail of the features characteristic distributions can cause problems for many of the commonly applied statistical methods of evaluation. Furthermore a re-appraisal of some conclusions drawn by previous works as to the presence of a fundamental scaling law in streamlined feature elongation is necessary due to evidence gathered here. Additionally; based on a limited sample size it has been found that it is not possible to differentiate a streamlined landform's core type based on their morphological characteristics alone. Larger 'known'-core data sets may be able to do so, based upon the length of a feature for example, however the sample size here was not sufficient to allow significant differences to come to the fore should they exist. And lastly, the extracted variable 'height' was found to account for the vast majoirty of the variance seen in the dataset when subject to a principle component analysis (PCA).

  2. Development of the brain's structural network efficiency in early adolescence: A longitudinal DTI twin study.

    PubMed

    Koenis, Marinka M G; Brouwer, Rachel M; van den Heuvel, Martijn P; Mandl, René C W; van Soelen, Inge L C; Kahn, René S; Boomsma, Dorret I; Hulshoff Pol, Hilleke E

    2015-12-01

    The brain is a network and our intelligence depends in part on the efficiency of this network. The network of adolescents differs from that of adults suggesting developmental changes. However, whether the network changes over time at the individual level and, if so, how this relates to intelligence, is unresolved in adolescence. In addition, the influence of genetic factors in the developing network is not known. Therefore, in a longitudinal study of 162 healthy adolescent twins and their siblings (mean age at baseline 9.9 [range 9.0-15.0] years), we mapped local and global structural network efficiency of cerebral fiber pathways (weighted with mean FA and streamline count) and assessed intelligence over a three-year interval. We find that the efficiency of the brain's structural network is highly heritable (locally up to 74%). FA-based local and global efficiency increases during early adolescence. Streamline count based local efficiency both increases and decreases, and global efficiency reorganizes to a net decrease. Local FA-based efficiency was correlated to IQ. Moreover, increases in FA-based network efficiency (global and local) and decreases in streamline count based local efficiency are related to increases in intellectual functioning. Individual changes in intelligence and local FA-based efficiency appear to go hand in hand in frontal and temporal areas. More widespread local decreases in streamline count based efficiency (frontal cingulate and occipital) are correlated with increases in intelligence. We conclude that the teenage brain is a network in progress in which individual differences in maturation relate to level of intellectual functioning. © 2015 Wiley Periodicals, Inc.

  3. Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography.

    PubMed

    Chen, Zhenrui; Tie, Yanmei; Olubiyi, Olutayo; Rigolo, Laura; Mehrtash, Alireza; Norton, Isaiah; Pasternak, Ofer; Rathi, Yogesh; Golby, Alexandra J; O'Donnell, Lauren J

    2015-01-01

    Diffusion imaging tractography is increasingly used to trace critical fiber tracts in brain tumor patients to reduce the risk of post-operative neurological deficit. However, the effects of peritumoral edema pose a challenge to conventional tractography using the standard diffusion tensor model. The aim of this study was to present a novel technique using a two-tensor unscented Kalman filter (UKF) algorithm to track the arcuate fasciculus (AF) in brain tumor patients with peritumoral edema. Ten right-handed patients with left-sided brain tumors in the vicinity of language-related cortex and evidence of significant peritumoral edema were retrospectively selected for the study. All patients underwent 3-Tesla magnetic resonance imaging (MRI) including a diffusion-weighted dataset with 31 directions. Fiber tractography was performed using both single-tensor streamline and two-tensor UKF tractography. A two-regions-of-interest approach was applied to perform the delineation of the AF. Results from the two different tractography algorithms were compared visually and quantitatively. Using single-tensor streamline tractography, the AF appeared disrupted in four patients and contained few fibers in the remaining six patients. Two-tensor UKF tractography delineated an AF that traversed edematous brain areas in all patients. The volume of the AF was significantly larger on two-tensor UKF than on single-tensor streamline tractography (p < 0.01). Two-tensor UKF tractography provides the ability to trace a larger volume AF than single-tensor streamline tractography in the setting of peritumoral edema in brain tumor patients.

  4. Methodology for the Design of Streamline-Traced External-Compression Supersonic Inlets

    NASA Technical Reports Server (NTRS)

    Slater, John W.

    2014-01-01

    A design methodology based on streamline-tracing is discussed for the design of external-compression, supersonic inlets for flight below Mach 2.0. The methodology establishes a supersonic compression surface and capture cross-section by tracing streamlines through an axisymmetric Busemann flowfield. The compression system of shock and Mach waves is altered through modifications to the leading edge and shoulder of the compression surface. An external terminal shock is established to create subsonic flow which is diffused in the subsonic diffuser. The design methodology was implemented into the SUPIN inlet design tool. SUPIN uses specified design factors to design the inlets and computes the inlet performance, which includes the flow rates, total pressure recovery, and wave drag. A design study was conducted using SUPIN and the Wind-US computational fluid dynamics code to design and analyze the properties of two streamline-traced, external-compression (STEX) supersonic inlets for Mach 1.6 freestream conditions. The STEX inlets were compared to axisymmetric pitot, two-dimensional, and axisymmetric spike inlets. The STEX inlets had slightly lower total pressure recovery and higher levels of total pressure distortion than the axisymmetric spike inlet. The cowl wave drag coefficients of the STEX inlets were 20% of those for the axisymmetric spike inlet. The STEX inlets had external sound pressures that were 37% of those of the axisymmetric spike inlet, which may result in lower adverse sonic boom characteristics. The flexibility of the shape of the capture cross-section may result in benefits for the integration of STEX inlets with aircraft.

  5. Method of measuring cross-flow vortices by use of an array of hot-film sensors

    NASA Technical Reports Server (NTRS)

    Agarwal, Aval K. (Inventor); Maddalon, Dal V. (Inventor); Mangalam, Siva M. (Inventor)

    1993-01-01

    The invention is a method for measuring the wavelength of cross-flow vortices of air flow having streamlines of flow traveling across a swept airfoil. The method comprises providing a plurality of hot-film sensors. Each hot-film sensor provides a signal which can be processed, and each hot-film sensor is spaced in a straight-line array such that the distance between successive hot-film sensors is less than the wavelength of the cross-flow vortices being measured. The method further comprises determining the direction of travel of the streamlines across the airfoil and positioning the straight-line array of hot film sensors perpendicular to the direction of travel of the streamlines, such that each sensor has a spanwise location. The method further comprises processing the signals provided by the sensors to provide root-mean-square values for each signal, plotting each root-mean-square value as a function of its spanwise location, and determining the wavelength of the cross-flow vortices by noting the distance between two maxima or two minima of root-mean-square values.

  6. Experiments and Analyses of the Formation of Erosional Scour Marks with Implications to the Origin of the Martian Outflow Channels

    NASA Technical Reports Server (NTRS)

    Komar, P. D.

    1985-01-01

    The objectives of the present study of erosional scour marks on Mars involve flume experiments to examine the details of scour patterns around a variety of obstacle shapes, and to review the engineering literature on the scour around bridge piers to determine whether those results might provide a quantitative evaluation of the flows which formed the scour marks in the outflow channels. The flume experiments completed to date examined the scour which develops around a circular island and around a streamlined island (having a lemniscate shape with length/width = 3.0). The islands themselves are non-erodable solids, but are surrounded by a fine-grained sediment bed. The scour patterns which occur around the circular island agree with those produced by prototype bridge piers and by scale-model piers employed in the engineering studies. The scour patterns around the model streamlined islands correspond extremely well with those seen adjacent to the streamlined islands on Mars, providing still more confirmation for a water-flow origin.

  7. Multi-Objective Aerodynamic Optimization of the Streamlined Shape of High-Speed Trains Based on the Kriging Model.

    PubMed

    Xu, Gang; Liang, Xifeng; Yao, Shuanbao; Chen, Dawei; Li, Zhiwei

    2017-01-01

    Minimizing the aerodynamic drag and the lift of the train coach remains a key issue for high-speed trains. With the development of computing technology and computational fluid dynamics (CFD) in the engineering field, CFD has been successfully applied to the design process of high-speed trains. However, developing a new streamlined shape for high-speed trains with excellent aerodynamic performance requires huge computational costs. Furthermore, relationships between multiple design variables and the aerodynamic loads are seldom obtained. In the present study, the Kriging surrogate model is used to perform a multi-objective optimization of the streamlined shape of high-speed trains, where the drag and the lift of the train coach are the optimization objectives. To improve the prediction accuracy of the Kriging model, the cross-validation method is used to construct the optimal Kriging model. The optimization results show that the two objectives are efficiently optimized, indicating that the optimization strategy used in the present study can greatly improve the optimization efficiency and meet the engineering requirements.

  8. The LEAN Payload Integration Process

    NASA Technical Reports Server (NTRS)

    Jordan, Lee P.; Young, Yancy; Rice, Amanda

    2011-01-01

    It is recognized that payload development and integration with the International Space Station (ISS) can be complex. This streamlined integration approach is a first step toward simplifying payload integration; making it easier to fly payloads on ISS, thereby increasing feasibility and interest for more research and commercial organizations to sponsor ISS payloads and take advantage of the ISS as a National Laboratory asset. The streamlined integration approach was addressed from the perspective of highly likely initial payload types to evolve from the National Lab Pathfinder program. Payloads to be accommodated by the Expedite the Processing of Experiments for Space Station (EXPRESS) Racks and Microgravity Sciences Glovebox (MSG) pressurized facilities have been addressed. It is hoped that the streamlined principles applied to these types of payloads will be analyzed and implemented in the future for other host facilities as well as unpressurized payloads to be accommodated by the EXPRESS Logistics Carrier (ELC). Further, a payload does not have to be classified as a National Lab payload in order to be processed according to the lean payload integration process; any payload that meets certain criteria can follow the lean payload integration process.

  9. On the Transition from Two-Dimensional to Three-Dimensional MHD Turbulence

    NASA Technical Reports Server (NTRS)

    Thess, A.; Zikanov, Oleg

    2004-01-01

    We report a theoretical investigation of the robustness of two-dimensional inviscid MHD flows at low magnetic Reynolds numbers with respect to three-dimensional perturbations. We analyze three model problems, namely flow in the interior of a triaxial ellipsoid, an unbounded vortex with elliptical streamlines, and a vortex sheet parallel to the magnetic field. We demonstrate that motion perpendicular to the magnetic field with elliptical streamlines becomes unstable with respect to the elliptical instability once the velocity has reached a critical magnitude whose value tends to zero as the eccentricity of the streamlines becomes large. Furthermore, vortex sheets parallel to the magnetic field, which are unstable for any velocity and any magnetic field, are found to emit eddies with vorticity perpendicular to the magnetic field and with an aspect ratio proportional to N(sup 1/2). The results suggest that purely two-dimensional motion without Joule energy dissipation is a singular type of flow which does not represent the asymptotic behaviour of three-dimensional MHD turbulence in the limit of infinitely strong magnetic fields.

  10. A three-dimensional, compressible, laminar boundary-layer method for general fuselages. Volume 1: Numerical method

    NASA Technical Reports Server (NTRS)

    Wie, Yong-Sun

    1990-01-01

    A procedure for calculating 3-D, compressible laminar boundary layer flow on general fuselage shapes is described. The boundary layer solutions can be obtained in either nonorthogonal 'body oriented' coordinates or orthogonal streamline coordinates. The numerical procedure is 'second order' accurate, efficient and independent of the cross flow velocity direction. Numerical results are presented for several test cases, including a sharp cone, an ellipsoid of revolution, and a general aircraft fuselage at angle of attack. Comparisons are made between numerical results obtained using nonorthogonal curvilinear 'body oriented' coordinates and streamline coordinates.

  11. A Method for Determining the Rate of Heat Transfer from a Wing or Streamline Body

    NASA Technical Reports Server (NTRS)

    Frick, Charles W; Mccullough, George B

    1945-01-01

    A method for calculating the rate of heat transfer from the surface of an airfoil or streamline body is presented. A comparison with the results of an experimental investigation indicates that the accuracy of the method is good. This method may be used to calculate the heat supply necessary for heat de-icing or in ascertaining the heat loss from the fuselage of an aircraft operating at great altitude. To illustrate the method, the total rate of heat transfer from an airfoil is calculated and compared with the experimental results.

  12. Turbulence modeling in simulation of gas-turbine flow and heat transfer.

    PubMed

    Brereton, G; Shih, T I

    2001-05-01

    The popular k-epsilon type two-equation turbulence models, which are calibrated by experimental data from simple shear flows, are analyzed for their ability to predict flows involving shear and an extra strain--flow with shear and rotation and flow with shear and streamline curvature. The analysis is based on comparisons between model predictions and those from measurements and large-eddy simulations of homogenous flows involving shear and an extra strain, either from rotation or from streamline curvature. Parameters are identified, which show the conditions under which performance of k-epsilon type models can be expected to be poor.

  13. Non-oscillatory and non-diffusive solution of convection problems by the iteratively reweighted least-squares finite element method

    NASA Technical Reports Server (NTRS)

    Jiang, Bo-Nan

    1993-01-01

    A comparative description is presented for the least-squares FEM (LSFEM) for 2D steady-state pure convection problems. In addition to exhibiting better control of the streamline derivative than the streamline upwinding Petrov-Galerkin method, numerical convergence rates are obtained which show the LSFEM to be virtually optimal. The LSFEM is used as a framework for an iteratively reweighted LSFEM yielding nonoscillatory and nondiffusive solutions for problems with contact discontinuities; this method is shown to convect contact discontinuities without error when using triangular and bilinear elements.

  14. The experimental verification of wall movement influence coefficients for an adaptive walled test section

    NASA Technical Reports Server (NTRS)

    Neal, G.

    1988-01-01

    Flexible walled wind tunnels have for some time been used to reduce wall interference effects at the model. A necessary part of the 3-D wall adjustment strategy being developed for the Transonic Self-Streamlining Wind Tunnel (TSWT) of Southampton University is the use of influence coefficients. The influence of a wall bump on the centerline flow in TSWT has been calculated theoretically using a streamline curvature program. This report details the experimental verification of these influence coefficients and concludes that it is valid to use the theoretically determined values in 3-D model testing.

  15. Generalized Fourier analyses of the advection-diffusion equation - Part I: one-dimensional domains

    NASA Astrophysics Data System (ADS)

    Christon, Mark A.; Martinez, Mario J.; Voth, Thomas E.

    2004-07-01

    This paper presents a detailed multi-methods comparison of the spatial errors associated with finite difference, finite element and finite volume semi-discretizations of the scalar advection-diffusion equation. The errors are reported in terms of non-dimensional phase and group speed, discrete diffusivity, artificial diffusivity, and grid-induced anisotropy. It is demonstrated that Fourier analysis provides an automatic process for separating the discrete advective operator into its symmetric and skew-symmetric components and characterizing the spectral behaviour of each operator. For each of the numerical methods considered, asymptotic truncation error and resolution estimates are presented for the limiting cases of pure advection and pure diffusion. It is demonstrated that streamline upwind Petrov-Galerkin and its control-volume finite element analogue, the streamline upwind control-volume method, produce both an artificial diffusivity and a concomitant phase speed adjustment in addition to the usual semi-discrete artifacts observed in the phase speed, group speed and diffusivity. The Galerkin finite element method and its streamline upwind derivatives are shown to exhibit super-convergent behaviour in terms of phase and group speed when a consistent mass matrix is used in the formulation. In contrast, the CVFEM method and its streamline upwind derivatives yield strictly second-order behaviour. In Part II of this paper, we consider two-dimensional semi-discretizations of the advection-diffusion equation and also assess the affects of grid-induced anisotropy observed in the non-dimensional phase speed, and the discrete and artificial diffusivities. Although this work can only be considered a first step in a comprehensive multi-methods analysis and comparison, it serves to identify some of the relative strengths and weaknesses of multiple numerical methods in a common analysis framework. Published in 2004 by John Wiley & Sons, Ltd.

  16. Tropical Cyclogenesis in a Tropical Wave Critical Layer: Easterly Waves

    NASA Technical Reports Server (NTRS)

    Dunkerton, T. J.; Montgomery, M. T.; Wang, Z.

    2009-01-01

    The development of tropical depressions within tropical waves over the Atlantic and eastern Pacific is usually preceded by a "surface low along the wave" as if to suggest a hybrid wave-vortex structure in which flow streamlines not only undulate with the waves, but form a closed circulation in the lower troposphere surrounding the low. This structure, equatorward of the easterly jet axis, is identified herein as the familiar critical layer of waves in shear flow, a flow configuration which arguably provides the simplest conceptual framework for tropical cyclogenesis resulting from tropical waves, their interaction with the mean flow, and with diabatic processes associated with deep moist convection. The recirculating Kelvin cat's eye within the critical layer represents a sweet spot for tropical cyclogenesis in which a proto-vortex may form and grow within its parent wave. A common location for storm development is given by the intersection of the wave's critical latitude and trough axis at the center of the cat's eye, with analyzed vorticity centroid nearby. The wave and vortex live together for a time, and initially propagate at approximately the same speed. In most cases this coupled propagation continues for a few days after a tropical depression is identified. For easterly waves, as the name suggests, the propagation is westward. It is shown that in order to visualize optimally the associated Lagrangian motions, one should view the flow streamlines, or stream function, in a frame of reference translating horizontally with the phase propagation of the parent wave. In this co-moving frame, streamlines are approximately equivalent to particle trajectories. The closed circulation is quasi-stationary, and a dividing streamline separates air within the cat's eye from air outside.

  17. The anatomy of extended limbic pathways in Asperger syndrome: a preliminary diffusion tensor imaging tractography study.

    PubMed

    Pugliese, Luca; Catani, Marco; Ameis, Stephanie; Dell'Acqua, Flavio; Thiebaut de Schotten, Michel; Murphy, Clodagh; Robertson, Dene; Deeley, Quinton; Daly, Eileen; Murphy, Declan G M

    2009-08-15

    It has been suggested that people with autistic spectrum disorder (ASD) have altered development (and connectivity) of limbic circuits. However, direct evidence of anatomical differences specific to white matter pathways underlying social behaviour and emotions in ASD is lacking. We used Diffusion Tensor Imaging Tractography to compare, in vivo, the microstructural integrity and age-related differences in the extended limbic pathways between subjects with Asperger syndrome and healthy controls. Twenty-four males with Asperger syndrome (mean age 23+/-12 years, age range: 9-54 years) and 42 age-matched male controls (mean age 25+/-10 years, age range: 9-54 years) were studied. We quantified tract-specific diffusivity measurements as indirect indexes of microstructural integrity (e.g. fractional anisotropy, FA; mean diffusivity, MD) and tract volume (e.g. number of streamlines) of the main limbic tracts. The dissected limbic pathways included the inferior longitudinal fasciculus, inferior frontal occipital fasciculus, uncinate, cingulum and fornix. There were no significant between-group differences in FA and MD. However, compared to healthy controls, individuals with Asperger syndrome had a significantly higher number of streamlines in the right (p=.003) and left (p=.03) cingulum, and in the right (p=.03) and left (p=.04) inferior longitudinal fasciculus. In contrast, people with Asperger syndrome had a significantly lower number of streamlines in the right uncinate (p=.02). Within each group there were significant age-related differences in MD and number of streamlines, but not FA. However, the only significant age-related between-group difference was in mean diffusivity of the left uncinate fasciculus (Z(obs)=2.05) (p=.02). Our preliminary findings suggest that people with Asperger syndrome have significant differences in the anatomy, and maturation, of some (but not all) limbic tracts.

  18. New evaluation index for the retainability of a swimmer's horizontal posture.

    PubMed

    Watanabe, Yasunori; Wakayoshi, Kohji; Nomura, Teruo

    2017-01-01

    This study aims to investigate the effect of changes in buoyancy when a swimmer respires in a horizontal posture. We attempted to evaluate the levelness of swimmers' streamline posture by simultaneously measuring the lung capacity and buoyancy under water. The buoyancy was measured based on the changes in the vertical loads of the upper and lower limbs on the subjects' streamline posture under water. The horizontal x-axis as lung ventilation and the vertical y-axis as buoyancy forms a linear equation y = ax + b. The relation between hand (upper-limb) buoyancy and lung ventilation is defined as y = a1x + b1 and that between foot (lower-limb) buoyancy and lung ventilation as y = a2x + b2. Horizontal levelness was calculated as a ratio by dividing a2 by a1 using the inclination (a) values from these formulas for an underwater streamline posture. We defined this ratio as the breathing-balance (BB) ratio. Although the performance levels in the present study did not show any difference in the absolute quantity of air that humans can inhale in a streamline posture, the BB ratio was higher in a statistically significant manner in junior swimmers competing at international levels compared with the other groups of subjects (P < 0.001). This statistical difference in horizontal levelness, despite the absence of a noticeable difference in the absolute quantity of inhaled air, may be attributable to the way in which each person inhales and exhales air. Top-level junior swimmers that exhibited a high BB ratio might have inhaled in a way that would counteract the sinking of the lower limbs, for example, through abdominal respiration. When exhaling, on the other hand, they might have let out air gradually to mitigate the acceleration force involved in submerging the lower limbs.

  19. Use of benchmarking techniques to justify the evolution of antibiotic management programs in healthcare systems.

    PubMed

    Schentag, J J; Paladino, J A; Birmingham, M C; Zimmer, G; Carr, J R; Hanson, S C

    1995-01-01

    To apply basic benchmarking techniques to hospital antibiotic expenditures and clinical pharmacy personnel and their duties, to identify cost savings strategies for clinical pharmacy services. Prospective survey of 18 hospitals ranging in size from 201 to 942 beds. Each was asked to provide antibiotic expenditures, an overview of their clinical pharmacy services, and to describe the duties of clinical pharmacists involved in antibiotic management activities. Specific information was sought on the use of pharmacokinetic dosing services, antibiotic streamlining, and oral switch in each of the hospitals. Most smaller hospitals (< 300 beds) did not employ clinical pharmacists with the specific duties of antibiotic management or streamlining. At these institutions, antibiotic management services consisted of formulary enforcement and aminoglycoside and/or vancomycin dosing services. The larger hospitals we surveyed employed clinical pharmacists designated as antibiotic management specialists, but their usual activities were aminoglycoside and/or vancomycin dosing services and formulary enforcement. In virtually all hospitals, the yearly expenses for antibiotics exceeded those of Millard Fillmore Hospitals by $2,000-3,000 per occupied bed. In a 500-bed hospital, this difference in expenditures would exceed $1.5 million yearly. Millard Fillmore Health System has similar types of patients, but employs clinical pharmacists to perform streamlining and/or switch functions at days 2-4, when cultures come back from the laboratory. The antibiotic streamlining and oral switch duties of clinical pharmacy specialists are associated with the majority of cost savings in hospital antibiotic management programs. The savings are considerable to the extent that most hospitals with 200-300 beds could readily cost-justify a full-time clinical pharmacist to perform these activities on a daily basis. Expenses of the program would be offset entirely by the reduction in the actual pharmacy expenditures on antibiotics.

  20. Numerical solution of the hypersonic viscous-shock-layer equations for laminar, transitional, and turbulent flows of a perfect gas over blunt axially symmetric bodies

    NASA Technical Reports Server (NTRS)

    Anderson, E. C.; Moss, J. N.

    1975-01-01

    The viscous shock layer equations applicable to hypersonic laminar, transitional, and turbulent flows of a perfect gas over two-dimensional plane or axially symmetric blunt bodies are presented. The equations are solved by means of an implicit finite difference scheme, and the results are compared with a turbulent boundary layer analysis. The agreement between the two solution procedures is satisfactory for the region of flow where streamline swallowing effects are negligible. For the downstream regions, where streamline swallowing effects are present, the expected differences in the two solution procedures are evident.

  1. Numerical design of streamlined tunnel walls for a two-dimensional transonic test

    NASA Technical Reports Server (NTRS)

    Newman, P. A.; Anderson, E. C.

    1978-01-01

    An analytical procedure is discussed for designing wall shapes for streamlined, nonporous, two-dimensional, transonic wind tunnels. It is based upon currently available 2-D inviscid transonic and boundary layer analysis computer programs. Predicted wall shapes are compared with experimental data obtained from the NASA Langley 6 by 19 inch Transonic Tunnel where the slotted walls were replaced by flexible nonporous walls. Comparisons are presented for the empty tunnel operating at a Mach number of 0.9 and for a supercritical test of an NACA 0012 airfoil at zero lift. Satisfactory agreement is obtained between the analytically and experimentally determined wall shapes.

  2. Two-dimensional Lagrangian simulation of suspended sediment

    USGS Publications Warehouse

    Schoellhamer, David H.

    1988-01-01

    A two-dimensional laterally averaged model for suspended sediment transport in steady gradually varied flow that is based on the Lagrangian reference frame is presented. The layered Lagrangian transport model (LLTM) for suspended sediment performs laterally averaged concentration. The elevations of nearly horizontal streamlines and the simulation time step are selected to optimize model stability and efficiency. The computational elements are parcels of water that are moved along the streamlines in the Lagrangian sense and are mixed with neighboring parcels. Three applications show that the LLTM can accurately simulate theoretical and empirical nonequilibrium suspended sediment distributions and slug injections of suspended sediment in a laboratory flume.

  3. Eco-friendly streamlined process for sporopollenin exine capsule extraction

    PubMed Central

    Mundargi, Raghavendra C.; Potroz, Michael G.; Park, Jae Hyeon; Seo, Jeongeun; Tan, Ee-Lin; Lee, Jae Ho; Cho, Nam-Joon

    2016-01-01

    Sporopollenin exine capsules (SECs) extracted from Lycopodium clavatum spores are an attractive biomaterial possessing a highly robust structure suitable for microencapsulation strategies. Despite several decades of research into SEC extraction methods, the protocols commonly used for L. clavatum still entail processing with both alkaline and acidolysis steps at temperatures up to 180 °C and lasting up to 7 days. Herein, we demonstrate a significantly streamlined processing regimen, which indicates that much lower temperatures and processing durations can be used without alkaline lysis. By employing CHN elemental analysis, scanning electron microscopy (SEM), confocal laser scanning microscopy (CLSM), and dynamic image particle analysis (DIPA), the optimum conditions for L. clavatum SEC processing were determined to include 30 hours acidolysis at 70 °C without alkaline lysis. Extending these findings to proof-of-concept encapsulation studies, we further demonstrate that our SECs are able to achieve a loading of 0.170 ± 0.01 g BSA per 1 g SECs by vacuum-assisted loading. Taken together, our streamlined processing method and corresponding characterization of SECs provides important insights for the development of applications including drug delivery, cosmetics, personal care products, and foods. PMID:26818918

  4. Exact Analytic Solution for a Ballistic Orbiting Wind

    NASA Astrophysics Data System (ADS)

    Wilkin, Francis P.; Hausner, Harry

    2017-07-01

    Much theoretical and observational work has been done on stellar winds within binary systems. We present a new solution for a ballistic wind launched from a source in a circular orbit. The solution is that of a single wind—no second wind is included in the system and the shocks that arise are those due to the orbiting wind interacting with itself. Our method emphasizes the curved streamlines in the corotating frame, where the flow is steady-state, allowing us to obtain an exact solution for the mass density at all pre-shock locations. Assuming an initially isotropic wind, fluid elements launched from the interior hemisphere of the wind will be the first to cross other streamlines, resulting in a spiral structure bounded by two shock surfaces. Streamlines from the outer wind hemisphere later intersect these shocks as well. An analytic solution is obtained for the geometry of the two shock surfaces. Although the inner and outer shock surfaces asymptotically trace Archimedean spirals, our tail solution suggests many crossings where the shocks overlap, beyond which the analytic solution cannot be continued. Our solution can be readily extended to an initially anisotropic wind.

  5. Eco-friendly streamlined process for sporopollenin exine capsule extraction

    NASA Astrophysics Data System (ADS)

    Mundargi, Raghavendra C.; Potroz, Michael G.; Park, Jae Hyeon; Seo, Jeongeun; Tan, Ee-Lin; Lee, Jae Ho; Cho, Nam-Joon

    2016-01-01

    Sporopollenin exine capsules (SECs) extracted from Lycopodium clavatum spores are an attractive biomaterial possessing a highly robust structure suitable for microencapsulation strategies. Despite several decades of research into SEC extraction methods, the protocols commonly used for L. clavatum still entail processing with both alkaline and acidolysis steps at temperatures up to 180 °C and lasting up to 7 days. Herein, we demonstrate a significantly streamlined processing regimen, which indicates that much lower temperatures and processing durations can be used without alkaline lysis. By employing CHN elemental analysis, scanning electron microscopy (SEM), confocal laser scanning microscopy (CLSM), and dynamic image particle analysis (DIPA), the optimum conditions for L. clavatum SEC processing were determined to include 30 hours acidolysis at 70 °C without alkaline lysis. Extending these findings to proof-of-concept encapsulation studies, we further demonstrate that our SECs are able to achieve a loading of 0.170 ± 0.01 g BSA per 1 g SECs by vacuum-assisted loading. Taken together, our streamlined processing method and corresponding characterization of SECs provides important insights for the development of applications including drug delivery, cosmetics, personal care products, and foods.

  6. Stratified Flow Past a Hill: Dividing Streamline Concept Revisited

    NASA Astrophysics Data System (ADS)

    Leo, Laura S.; Thompson, Michael Y.; Di Sabatino, Silvana; Fernando, Harindra J. S.

    2016-06-01

    The Sheppard formula (Q J R Meteorol Soc 82:528-529, 1956) for the dividing streamline height H_s assumes a uniform velocity U_∞ and a constant buoyancy frequency N for the approach flow towards a mountain of height h, and takes the form H_s/h=( {1-F} ) , where F=U_{∞}/Nh. We extend this solution to a logarithmic approach-velocity profile with constant N. An analytical solution is obtained for H_s/h in terms of Lambert-W functions, which also suggests alternative scaling for H_s/h. A `modified' logarithmic velocity profile is proposed for stably stratified atmospheric boundary-layer flows. A field experiment designed to observe H_s is described, which utilized instrumentation from the spring field campaign of the Mountain Terrain Atmospheric Modeling and Observations (MATERHORN) Program. Multiple releases of smoke at F≈ 0.3-0.4 support the new formulation, notwithstanding the limited success of experiments due to logistical constraints. No dividing streamline is discerned for F≈ 10, since, if present, it is too close to the foothill. Flow separation and vortex shedding is observed in this case. The proposed modified logarithmic profile is in reasonable agreement with experimental observations.

  7. Advances in Measurement of Skin Friction in Airflow

    NASA Technical Reports Server (NTRS)

    Brown, James L.; Naughton, Jonathan W.

    2006-01-01

    The surface interferometric skin-friction (SISF) measurement system is an instrument for determining the distribution of surface shear stress (skin friction) on a wind-tunnel model. The SISF system utilizes the established oil-film interference method, along with advanced image-data-processing techniques and mathematical models that express the relationship between interferograms and skin friction, to determine the distribution of skin friction over an observed region of the surface of a model during a single wind-tunnel test. In the oil-film interference method, a wind-tunnel model is coated with a thin film of oil of known viscosity and is illuminated with quasi-monochromatic, collimated light, typically from a mercury lamp. The light reflected from the outer surface of the oil film interferes with the light reflected from the oil-covered surface of the model. In the present version of the oil-film interference method, a camera captures an image of the illuminated model and the image in the camera is modulated by the interference pattern. The interference pattern depends on the oil-thickness distribution on the observed surface, and this distribution can be extracted through analysis of the image acquired by the camera. The oil-film technique is augmented by a tracer technique for observing the streamline pattern. To make the streamlines visible, small dots of fluorescentchalk/oil mixture are placed on the model just before a test. During the test, the chalk particles are embedded in the oil flow and produce chalk streaks that mark the streamlines. The instantaneous rate of thinning of the oil film at a given position on the surface of the model can be expressed as a function of the instantaneous thickness, the skin-friction distribution on the surface, and the streamline pattern on the surface; the functional relationship is expressed by a mathematical model that is nonlinear in the oil-film thickness and is known simply as the thin-oil-film equation. From the image data acquired as described, the time-dependent oil-thickness distribution and streamline pattern are extracted and by inversion of the thin-oil-film equation it is then possible to determine the skin-friction distribution. In addition to a quasi-monochromatic light source, the SISF system includes a beam splitter and two video cameras equipped with filters for observing the same area on a model in different wavelength ranges, plus a frame grabber and a computer for digitizing the video images and processing the image data. One video camera acquires the interference pattern in a narrow wavelength range of the quasi-monochromatic source. The other video camera acquires the streamline image of fluorescence from the chalk in a nearby but wider wavelength range. The interference- pattern and fluorescence images are digitized, and the resulting data are processed by an algorithm that inverts the thin-oil-film equation to find the skin-friction distribution.

  8. Surface flow and heating distributions on a cylinder in near wake of Aeroassist Flight Experiment (AFE) configuration at incidence in Mach 10 Air

    NASA Technical Reports Server (NTRS)

    Wells, William L.

    1990-01-01

    Experimental heat transfer distributions and surface streamline directions are presented for a cylinder in the near wake of the Aeroassist Flight Experiment forebody configuration. Tests were conducted in air at a nominal free stream Mach number of 10, with post shock Reynolds numbers based on model base height of 6,450 to 50,770, and angles of attack of 5, 0, -5, and -10 degrees. Heat transfer data were obtained with thin film resistance gage and surface streamline directions by the oil flow technique. Comparisons between measured values and predicted values were made by using a Navier-Stokes computer code.

  9. Upgrades to Electronic Speckle Interferometer (ESPI) Operation and Data Analysis at NASA's Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Connelly, Joseph; Blake, Peter; Jones, Joycelyn

    2008-01-01

    The authors report operational upgrades and streamlined data analysis of a commissioned electronic speckle interferometer (ESPI) in a permanent in-house facility at NASA's Goddard Space Flight Center. Our ESPI was commercially purchased for use by the James Webb Space Telescope (JWST) development team. We have quantified and reduced systematic error sources, improved the software operability with a user-friendly graphic interface, developed an instrument simulator, streamlined data analysis for long-duration testing, and implemented a turn-key approach to speckle interferometry. We also summarize results from a test of the JWST support structure (previously published), and present new results from several pieces of test hardware at various environmental conditions.

  10. Revised FORTRAN program for calculating velocities and streamlines on the hub-shroud midchannel stream surface of an axial-, radial-, or mixed-flow turbomachine or annular duct. 2: Programmer's manual

    NASA Technical Reports Server (NTRS)

    Katsanis, T.; Mcnally, W. D.

    1977-01-01

    A FORTRAN IV computer program has been developed that obtains a detailed subsonic or shock free transonic flow solution on the hub-shroud midchannel stream surface of a turbomachine. The blade row may be fixed or rotating, and the blades may be twisted and leaned. Flow may be axial, mixed, or radial. Upstream and downstream flow variables may vary from hub to shroud, and provisions are made to correct for loss of stagnation pressure. The results include velocities, streamlines, and flow angles on the stream surface and approximate blade surface velocities.

  11. Streamlined Genome Sequence Compression using Distributed Source Coding

    PubMed Central

    Wang, Shuang; Jiang, Xiaoqian; Chen, Feng; Cui, Lijuan; Cheng, Samuel

    2014-01-01

    We aim at developing a streamlined genome sequence compression algorithm to support alternative miniaturized sequencing devices, which have limited communication, storage, and computation power. Existing techniques that require heavy client (encoder side) cannot be applied. To tackle this challenge, we carefully examined distributed source coding theory and developed a customized reference-based genome compression protocol to meet the low-complexity need at the client side. Based on the variation between source and reference, our protocol will pick adaptively either syndrome coding or hash coding to compress subsequences of changing code length. Our experimental results showed promising performance of the proposed method when compared with the state-of-the-art algorithm (GRS). PMID:25520552

  12. Streamlined Island

    NASA Technical Reports Server (NTRS)

    2003-01-01

    MGS MOC Release No. MOC2-514, 15 October 2003

    This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) picture shows a streamlined island in Marte Vallis, a large outflow channel system that crosses the 180oW meridian between the Elysium and Amazonis regions of Mars. The flow patterns on the floor of Marte Vallis might be the remains of lava flows or mud flows. Marte is the Spanish word for Mars. Most of the largest valleys on the red planet are named for 'Mars' in various languages. This island is located near 21.8oN, 175.3oW. The picture covers an area 3 km (1.9 mi) wide and is illuminated by sunlight from the lower left.

  13. A Study of Two-Equation Turbulence Models on the Elliptic Streamline Flow

    NASA Technical Reports Server (NTRS)

    Blaisdell, Gregory A.; Qin, Jim H.; Shariff, Karim; Rai, Man Mohan (Technical Monitor)

    1995-01-01

    Several two-equation turbulence models are compared to data from direct numerical simulations (DNS) of the homogeneous elliptic streamline flow, which combines rotation and strain. The models considered include standard two-equation models and models with corrections for rotational effects. Most of the rotational corrections modify the dissipation rate equation to account for the reduced dissipation rate in rotating turbulent flows, however, the DNS data shows that the production term in the turbulent kinetic energy equation is not modeled correctly by these models. Nonlinear relations for the Reynolds stresses are considered as a means of modifying the production term. Implications for the modeling of turbulent vortices will be discussed.

  14. Modeling surgical tool selection patterns as a "traveling salesman problem" for optimizing a modular surgical tool system.

    PubMed

    Nelson, Carl A; Miller, David J; Oleynikov, Dmitry

    2008-01-01

    As modular systems come into the forefront of robotic telesurgery, streamlining the process of selecting surgical tools becomes an important consideration. This paper presents a method for optimal queuing of tools in modular surgical tool systems, based on patterns in tool-use sequences, in order to minimize time spent changing tools. The solution approach is to model the set of tools as a graph, with tool-change frequency expressed as edge weights in the graph, and to solve the Traveling Salesman Problem for the graph. In a set of simulations, this method has shown superior performance at optimizing tool arrangements for streamlining surgical procedures.

  15. Learn about Smart Sectors

    EPA Pesticide Factsheets

    about the Smart Sectors program including: Meaningful Collaboration with Regulated Sectors; Sensible Policies to Improve Environmental Outcomes; Better EPA Practices and Streamlined Operations; Historical Context

  16. 'Items for criticism (not in sequence)': Joseph DeLee, Pare Lorentz and The Fight for Life (1940).

    PubMed

    Gainty, Caitjan

    2017-09-01

    In the late 1920s, the American obstetrician Joseph DeLee brought the motion-picture camera into the birth room. Following that era's trend of adapting industrial efficiency practices for medical environments, DeLee's films give spectacular and unexpected expression to the engineering concept of 'streamlining'. Accomplishing what more tangible obstetric streamlining practices had failed to, DeLee's cameras, and his post-production manipulation, shifted birth from messy and dangerous to rationalized, efficient, death-defying. This was film as an active and effective medical tool. Years later, the documentarian Pare Lorentz produced and wrote his own birth film, The Fight for Life (1940). The documentary subject of the film was DeLee himself, and the film was set in his hospitals, on the same maternity 'sets' that had once showcased film's remarkable streamlining capacity to give and keep life. Yet relatively little of DeLee was retained in the film's content, resulting in a showdown that, by way of contrast, further articulated DeLee's understanding of film's medical powers and, in so doing, hinted at a more dynamic moment in the history of medicine while speaking also to the process by which that understanding ceased to be historically legible.

  17. Mapping Topographic Structure in White Matter Pathways with Level Set Trees

    PubMed Central

    Kent, Brian P.; Rinaldo, Alessandro; Yeh, Fang-Cheng; Verstynen, Timothy

    2014-01-01

    Fiber tractography on diffusion imaging data offers rich potential for describing white matter pathways in the human brain, but characterizing the spatial organization in these large and complex data sets remains a challenge. We show that level set trees–which provide a concise representation of the hierarchical mode structure of probability density functions–offer a statistically-principled framework for visualizing and analyzing topography in fiber streamlines. Using diffusion spectrum imaging data collected on neurologically healthy controls (N = 30), we mapped white matter pathways from the cortex into the striatum using a deterministic tractography algorithm that estimates fiber bundles as dimensionless streamlines. Level set trees were used for interactive exploration of patterns in the endpoint distributions of the mapped fiber pathways and an efficient segmentation of the pathways that had empirical accuracy comparable to standard nonparametric clustering techniques. We show that level set trees can also be generalized to model pseudo-density functions in order to analyze a broader array of data types, including entire fiber streamlines. Finally, resampling methods show the reliability of the level set tree as a descriptive measure of topographic structure, illustrating its potential as a statistical descriptor in brain imaging analysis. These results highlight the broad applicability of level set trees for visualizing and analyzing high-dimensional data like fiber tractography output. PMID:24714673

  18. Streamlining environmental product declarations: a stage model

    NASA Astrophysics Data System (ADS)

    Lefebvre, Elisabeth; Lefebvre, Louis A.; Talbot, Stephane; Le Hen, Gael

    2001-02-01

    General public environmental awareness and education is increasing, therefore stimulating the demand for reliable, objective and comparable information about products' environmental performances. The recently published standard series ISO 14040 and ISO 14025 are normalizing the preparation of Environmental Product Declarations (EPDs) containing comprehensive information relevant to a product's environmental impact during its life cycle. So far, only a few environmentally leading manufacturing organizations have experimented the preparation of EPDs (mostly from Europe), demonstrating its great potential as a marketing weapon. However the preparation of EPDs is a complex process, requiring collection and analysis of massive amounts of information coming from disparate sources (suppliers, sub-contractors, etc.). In a foreseeable future, the streamlining of the EPD preparation process will require product manufacturers to adapt their information systems (ERP, MES, SCADA) in order to make them capable of gathering, and transmitting the appropriate environmental information. It also requires strong functional integration all along the product supply chain in order to ensure that all the information is made available in a standardized and timely manner. The goal of the present paper is two fold: first to propose a transitional model towards green supply chain management and EPD preparation; second to identify key technologies and methodologies allowing to streamline the EPD process and subsequently the transition toward sustainable product development

  19. Decreasing laboratory turnaround time and patient wait time by implementing process improvement methodologies in an outpatient oncology infusion unit.

    PubMed

    Gjolaj, Lauren N; Gari, Gloria A; Olier-Pino, Angela I; Garcia, Juan D; Fernandez, Gustavo L

    2014-11-01

    Prolonged patient wait times in the outpatient oncology infusion unit indicated a need to streamline phlebotomy processes by using existing resources to decrease laboratory turnaround time and improve patient wait time. Using the DMAIC (define, measure, analyze, improve, control) method, a project to streamline phlebotomy processes within the outpatient oncology infusion unit in an academic Comprehensive Cancer Center known as the Comprehensive Treatment Unit (CTU) was completed. Laboratory turnaround time for patients who needed same-day lab and CTU services and wait time for all CTU patients was tracked for 9 weeks. During the pilot, the wait time from arrival to CTU to sitting in treatment area decreased by 17% for all patients treated in the CTU during the pilot. A total of 528 patients were seen at the CTU phlebotomy location, representing 16% of the total patients who received treatment in the CTU, with a mean turnaround time of 24 minutes compared with a baseline turnaround time of 51 minutes. Streamlining workflows and placing a phlebotomy station inside of the CTU decreased laboratory turnaround times by 53% for patients requiring same day lab and CTU services. The success of the pilot project prompted the team to make the station a permanent fixture. Copyright © 2014 by American Society of Clinical Oncology.

  20. Streamline similarity method for flow distributions and shock losses at the impeller inlet of the centrifugal pump

    NASA Astrophysics Data System (ADS)

    Zhang, Zh.

    2018-02-01

    An analytical method is presented, which enables the non-uniform velocity and pressure distributions at the impeller inlet of a pump to be accurately computed. The analyses are based on the potential flow theory and the geometrical similarity of the streamline distribution along the leading edge of the impeller blades. The method is thus called streamline similarity method (SSM). The obtained geometrical form of the flow distribution is then simply described by the geometrical variable G( s) and the first structural constant G I . As clearly demonstrated and also validated by experiments, both the flow velocity and the pressure distributions at the impeller inlet are usually highly non-uniform. This knowledge is indispensible for impeller blade designs to fulfill the shockless inlet flow condition. By introducing the second structural constant G II , the paper also presents the simple and accurate computation of the shock loss, which occurs at the impeller inlet. The introduction of two structural constants contributes immensely to the enhancement of the computational accuracies. As further indicated, all computations presented in this paper can also be well applied to the non-uniform exit flow out of an impeller of the Francis turbine for accurately computing the related mean values.

  1. Self-diffusion in the non-Newtonian regime of shearing liquid crystal model systems based on the Gay-Berne potential

    NASA Astrophysics Data System (ADS)

    Sarman, Sten; Wang, Yong-Lei; Laaksonen, Aatto

    2016-02-01

    The self-diffusion coefficients of nematic phases of various model systems consisting of regular convex calamitic and discotic ellipsoids and non-convex bodies such as bent-core molecules and soft ellipsoid strings have been obtained as functions of the shear rate in a shear flow. Then the self-diffusion coefficient is a second rank tensor with three different diagonal components and two off-diagonal components. These coefficients were found to be determined by a combination of two mechanisms, which previously have been found to govern the self-diffusion of shearing isotropic liquids, namely, (i) shear alignment enhancing the diffusion in the direction parallel to the streamlines and hindering the diffusion in the perpendicular directions and (ii) the distortion of the shell structure in the liquid whereby a molecule more readily can escape from a surrounding shell of nearest neighbors, so that the mobility increases in every direction. Thus, the diffusion parallel to the streamlines always increases with the shear rate since these mechanisms cooperate in this direction. In the perpendicular directions, these mechanisms counteract each other so that the behaviour becomes less regular. In the case of the nematic phases of the calamitic and discotic ellipsoids and of the bent core molecules, mechanism (ii) prevails so that the diffusion coefficients increase. However, the diffusion coefficients of the soft ellipsoid strings decrease in the direction of the velocity gradient because the broadsides of these molecules are oriented perpendicularly to this direction due the shear alignment (i). The cross coupling coefficient relating a gradient of tracer particles in the direction of the velocity gradient and their flow in the direction of the streamlines is negative and rather large, whereas the other coupling coefficient relating a gradient in the direction of the streamlines and a flow in the direction of the velocity gradient is very small.

  2. Users manual for the NASA Lewis three-dimensional ice accretion code (LEWICE 3D)

    NASA Technical Reports Server (NTRS)

    Bidwell, Colin S.; Potapczuk, Mark G.

    1993-01-01

    A description of the methodology, the algorithms, and the input and output data along with an example case for the NASA Lewis 3D ice accretion code (LEWICE3D) has been produced. The manual has been designed to help the user understand the capabilities, the methodologies, and the use of the code. The LEWICE3D code is a conglomeration of several codes for the purpose of calculating ice shapes on three-dimensional external surfaces. A three-dimensional external flow panel code is incorporated which has the capability of calculating flow about arbitrary 3D lifting and nonlifting bodies with external flow. A fourth order Runge-Kutta integration scheme is used to calculate arbitrary streamlines. An Adams type predictor-corrector trajectory integration scheme has been included to calculate arbitrary trajectories. Schemes for calculating tangent trajectories, collection efficiencies, and concentration factors for arbitrary regions of interest for single droplets or droplet distributions have been incorporated. A LEWICE 2D based heat transfer algorithm can be used to calculate ice accretions along surface streamlines. A geometry modification scheme is incorporated which calculates the new geometry based on the ice accretions generated at each section of interest. The three-dimensional ice accretion calculation is based on the LEWICE 2D calculation. Both codes calculate the flow, pressure distribution, and collection efficiency distribution along surface streamlines. For both codes the heat transfer calculation is divided into two regions, one above the stagnation point and one below the stagnation point, and solved for each region assuming a flat plate with pressure distribution. Water is assumed to follow the surface streamlines, hence starting at the stagnation zone any water that is not frozen out at a control volume is assumed to run back into the next control volume. After the amount of frozen water at each control volume has been calculated the geometry is modified by adding the ice at each control volume in the surface normal direction.

  3. New evaluation index for the retainability of a swimmer’s horizontal posture

    PubMed Central

    2017-01-01

    This study aims to investigate the effect of changes in buoyancy when a swimmer respires in a horizontal posture. We attempted to evaluate the levelness of swimmers’ streamline posture by simultaneously measuring the lung capacity and buoyancy under water. The buoyancy was measured based on the changes in the vertical loads of the upper and lower limbs on the subjects’ streamline posture under water. The horizontal x-axis as lung ventilation and the vertical y-axis as buoyancy forms a linear equation y = ax + b. The relation between hand (upper-limb) buoyancy and lung ventilation is defined as y = a1x + b1 and that between foot (lower-limb) buoyancy and lung ventilation as y = a2x + b2. Horizontal levelness was calculated as a ratio by dividing a2 by a1 using the inclination (a) values from these formulas for an underwater streamline posture. We defined this ratio as the breathing–balance (BB) ratio. Although the performance levels in the present study did not show any difference in the absolute quantity of air that humans can inhale in a streamline posture, the BB ratio was higher in a statistically significant manner in junior swimmers competing at international levels compared with the other groups of subjects (P < 0.001). This statistical difference in horizontal levelness, despite the absence of a noticeable difference in the absolute quantity of inhaled air, may be attributable to the way in which each person inhales and exhales air. Top-level junior swimmers that exhibited a high BB ratio might have inhaled in a way that would counteract the sinking of the lower limbs, for example, through abdominal respiration. When exhaling, on the other hand, they might have let out air gradually to mitigate the acceleration force involved in submerging the lower limbs. PMID:28486565

  4. Four Single-Page Learning Models.

    ERIC Educational Resources Information Center

    Hlynka, Denis

    1979-01-01

    Identifies four models of single-page learning systems that can streamline lengthy, complex prose: Information Mapping, Focal Press Model, Behavioral Objectives Model, and School Mathematics Model. (CMV)

  5. Streamlined Total Synthesis of Trioxacarcins and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues Thereof. Discovery of Simpler Designed and Potent Trioxacarcin Analogues.

    PubMed

    Nicolaou, K C; Chen, Pengxi; Zhu, Shugao; Cai, Quan; Erande, Rohan D; Li, Ruofan; Sun, Hongbao; Pulukuri, Kiran Kumar; Rigol, Stephan; Aujay, Monette; Sandoval, Joseph; Gavrilyuk, Julia

    2017-11-01

    A streamlined total synthesis of the naturally occurring antitumor agents trioxacarcins is described, along with its application to the construction of a series of designed analogues of these complex natural products. Biological evaluation of the synthesized compounds revealed a number of highly potent, and yet structurally simpler, compounds that are effective against certain cancer cell lines, including a drug-resistant line. A novel one-step synthesis of anthraquinones and chloro anthraquinones from simple ketone precursors and phenylselenyl chloride is also described. The reported work, featuring novel chemistry and cascade reactions, has potential applications in cancer therapy, including targeted approaches as in antibody-drug conjugates.

  6. An Elliptic PDE Approach for Shape Characterization

    PubMed Central

    Haidar, Haissam; Bouix, Sylvain; Levitt, James; McCarley, Robert W.; Shenton, Martha E.; Soul, Janet S.

    2009-01-01

    This paper presents a novel approach to analyze the shape of anatomical structures. Our methodology is rooted in classical physics and in particular Poisson's equation, a fundamental partial differential equation [1]. The solution to this equation and more specifically its equipotential surfaces display properties that are useful for shape analysis. We present a numerical algorithm to calculate the length of streamlines formed by the gradient field of the solution to this equation for 2D and 3D objects. The length of the streamlines along the equipotential surfaces was used to build a new function which can characterize the shape of objects. We illustrate our method on 2D synthetic and natural shapes as well as 3D medical data. PMID:17271986

  7. Scale-invariant streamline equations and strings of singular vorticity for perturbed anisotropic solutions of the Navier-Stokes equation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Libin, A., E-mail: a_libin@netvision.net.il

    2012-12-15

    A linear combination of a pair of dual anisotropic decaying Beltrami flows with spatially constant amplitudes (the Trkal solutions) with the same eigenvalue of the curl operator and of a constant velocity orthogonal vector to the Beltrami pair yields a triplet solution of the force-free Navier-Stokes equation. The amplitudes slightly variable in space (large scale perturbations) yield the emergence of a time-dependent phase between the dual Beltrami flows and of the upward velocity, which are unstable at large values of the Reynolds number. They also lead to the formation of large-scale curved prisms of streamlines with edges being the stringsmore » of singular vorticity.« less

  8. Analytical Work in Support of the Design and Operation of Two Dimensional Self Streamlining Test Sections

    NASA Technical Reports Server (NTRS)

    Judd, M.; Wolf, S. W. D.; Goodyer, M. J.

    1976-01-01

    A method has been developed for accurately computing the imaginary flow fields outside a flexible walled test section, applicable to lifting and non-lifting models. The tolerances in the setting of the flexible walls introduce only small levels of aerodynamic interference at the model. While it is not possible to apply corrections for the interference effects, they may be reduced by improving the setting accuracy of the portions of wall immediately above and below the model. Interference effects of the truncation of the length of the streamlined portion of a test section are brought to an acceptably small level by the use of a suitably long test section with the model placed centrally.

  9. Discussion of boundary-layer characteristics near the casing of an axial-flow compressor

    NASA Technical Reports Server (NTRS)

    Mager, Artur; Mahoney, John J; Budinger, Ray E

    1951-01-01

    Boundary-layer velocity profiles on the casing of an axial-flow compressor behind the guide vanes and rotor were measured and resolved into two components: along the streamline of the flow and perpendicular to it. Boundary-layer thickness and the deflection of the boundary layer at the wall were the generalizing parameters. By use of these results and the momentum-integral equations, the characteristics of boundary on the walls of axial-flow compressor are qualitatively discussed. Important parameters concerning secondary flow in the boundary layer appear to be turning of the flow and the product of boundary-layer thickness and streamline curvature outside the boundary layer. Two types of separation are shown to be possible in three dimensional boundary layer.

  10. Correcting For Seed-Particle Lag In LV Measurements

    NASA Technical Reports Server (NTRS)

    Jones, Gregory S.; Gartrell, Luther R.; Kamemoto, Derek Y.

    1994-01-01

    Two experiments conducted to evaluate effects of sizes of seed particles on errors in LV measurements of mean flows. Both theoretical and conventional experimental methods used to evaluate errors. First experiment focused on measurement of decelerating stagnation streamline of low-speed flow around circular cylinder with two-dimensional afterbody. Second performed in transonic flow and involved measurement of decelerating stagnation streamline of hemisphere with cylindrical afterbody. Concluded, mean-quantity LV measurements subject to large errors directly attributable to sizes of particles. Predictions of particle-response theory showed good agreement with experimental results, indicating velocity-error-correction technique used in study viable for increasing accuracy of laser velocimetry measurements. Technique simple and useful in any research facility in which flow velocities measured.

  11. Investigation of heat flux on aerodynamic body in supersonic gas flow with local energy deposition

    NASA Astrophysics Data System (ADS)

    Dobrov, Y. V.; Lashkov, V. A.; Mashek, I. Ch.; Khoronzhuk, R. S.

    2018-05-01

    Existence and intensive growth of heat flux on a vehicle is one of the main problems in hypersonic flight. Experimental study of heat flux in the stagnation point of a blunt cylinder in supersonic flow was made using gradient heat flux sensor. It was found that a transfer function of the measuring system should be used for obtaining data at fast-changing heat flux measurements. It was established that it was possible to produce a short-term heat transfer from the surface of streamlined body with the help of microwave discharge. Numerical simulation showed that it is possible to change nature of the flow by means of local energy deposition in case of streamlined wedge.

  12. LOADING SIMULATION PROGRAM C

    EPA Pesticide Factsheets

    LSPC is the Loading Simulation Program in C++, a watershed modeling system that includes streamlined Hydrologic Simulation Program Fortran (HSPF) algorithms for simulating hydrology, sediment, and general water quality

  13. Polyelectrolyte-coated ion exchangers for cell-resistant expanded bed adsorption.

    PubMed

    Dainiak, Maria B; Galaev, Igor Yu; Mattiasson, Bo

    2002-01-01

    Adsorption chromatography in expanded beds is a widely used technology for direct capture of target proteins from fermentation broths. However, in many cases this method cannot be applied as a result of the strong tendency of cells or cell debris to interact with the adsorbent beads. To prevent contamination of the expanded bed with the biomass, STREAMLINE DEAE, anion exchanger designed for expanded bed adsorption, was modified with a layer of poly(acrylic acid) (PAA). The shielding layer of polyelectrolyte was attached to the surface of the matrix beads via electrostatic interactions. PAA with a high degree of polymerization was chosen to prevent diffusion of large polymer molecules into the pores of adsorbent. Thus, the shielding layer of PAA was adsorbed only at the mouth of the pores of STREAMLINE DEAE beads and only marginally decreased the binding capacity of the ion exchanger for bovine serum albumin, the model protein in this study. PAA-coated STREAMLINE DEAE practically did not interact with yeast cells, which otherwise bound strongly to the native adsorbent at neutral conditions. Cell-resistant PAA-coated anion exchanger was successfully used for isolation of BSA from the model protein mixture containing BSA, lysozyme (positively charged at applied conditions), and yeast cells. The layer of PAA was stable under mild elution conditions, and the modified adsorbent could be used in the repeated purification cycles.

  14. INDICATION OF THE BLACK HOLE POWERED JET IN M87 BY VSOP OBSERVATIONS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Asada, Keiichi; Nakamura, Masanori; Pu, Hung-Yi, E-mail: asada@asiaa.sinica.edu.tw, E-mail: nakamura@asiaa.sinica.edu.tw, E-mail: hypu@asiaa.sinica.edu.tw

    2016-12-10

    In order to study the collimation and acceleration mechanism of relativistic jets, the jet streamline of M87 at milliarcsecond scale is extensively investigated with images from VSOP observations at 1.6 and 5 GHz. Thanks to the higher angular resolution of VSOP, especially in the direction transverse to the jet, we resolved the jet streamline into three ridgelines at the scale of milli arcseconds. While the properties of the outer two ridgelines are in good agreement with those measured in previous observations and can be expressed by one power-law line with a power law index of 1.7, an inner ridgeline ismore » clearly observed for the first time. We compared the measured size with the outermost streamline expected by Blandford and Znajek's parabolic solutions, which are anchored at the event horizon, with different black hole spin parameters. We revealed that the observed inner ridgeline is narrower than the prediction, suggesting the origin of the inner ridgeline to be part of a spine originating from the spinning black hole. The inner ridgeline becomes very dim at large distances from the central engine at 5 GHz. We considered two possible cases for this; Doppler beaming and/or radiative cooling. Either case seems to be reasonable for its explanation, and future multi-frequency observations will discriminate those two possibilities.« less

  15. Multi-faceted informatics system for digitising and streamlining the reablement care model.

    PubMed

    Bond, Raymond R; Mulvenna, Maurice D; Finlay, Dewar D; Martin, Suzanne

    2015-08-01

    Reablement is new paradigm to increase independence in the home amongst the ageing population. And it remains a challenge to design an optimal electronic system to streamline and integrate reablement into current healthcare infrastructure. Furthermore, given reablement requires collaboration with a range of organisations (including national healthcare institutions and community/voluntary service providers), such a system needs to be co-created with all stakeholders involved. Thus, the purpose of this study is, (1) to bring together stakeholder groups to elicit a comprehensive set of requirements for a digital reablement system, (2) to utilise emerging technologies to implement a system and a data model based on the requirements gathered and (3) to involve user groups in a usability assessment of the system. In this study we employed a mixed qualitative approach that included a series of stakeholder-involved activities. Collectively, 73 subjects were recruited to participate in an ideation event, a quasi-hackathon and a usability study. The study unveiled stakeholder-led requirements, which resulted in a novel cloud-based system that was created using emerging web technologies. The system is driven by a unique data model and includes interactive features that are necessary for streamlining the reablement care model. In summary, this system allows community based interventions (or services) to be prescribed to occupants whilst also monitoring the occupant's progress of independent living. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. BLIMPK/Streamline Surface Catalytic Heating Predictions on the Space Shuttle Orbiter

    NASA Technical Reports Server (NTRS)

    Marichalar, Jeremiah J.; Rochelle, William C.; Kirk, Benjamin S.; Campbell, Charles H.

    2006-01-01

    This paper describes the results of an analysis of localized catalytic heating effects to the U.S. Space Shuttle Orbiter Thermal Protection System (TPS). The analysis applies to the High-temperature Reusable Surface Insulation (HRSI) on the lower fuselage and wing acreage, as well as the critical Reinforced Carbon-Carbon on the nose cap, chin panel and the wing leading edge. The object of the analysis was to use a modified two-layer approach to predict the catalytic heating effects on the Orbiter windward HRSI tile acreage, nose cap, and wing leading edge assuming localized highly catalytic or fully catalytic surfaces. The method incorporated the Boundary Layer Integral Matrix Procedure Kinetic (BLIMPK) code with streamline inputs from viscous Navier-Stokes solutions to produce heating rates for localized fully catalytic and highly catalytic surfaces as well as for nominal partially catalytic surfaces (either Reinforced Carbon-Carbon or Reaction Cured Glass) with temperature-dependent recombination coefficients. The highly catalytic heating results showed very good correlation with Orbiter Experiments STS-2, -3, and -5 centerline and STS-5 wing flight data for the HRSI tiles. Recommended catalytic heating factors were generated for use in future Shuttle missions in the event of quick-time analysis of damaged or repaired TPS areas during atmospheric reentry. The catalytic factors are presented along the streamlines as well as a function of stagnation enthalpy so they can be used for arbitrary trajectories.

  17. AN INTEGRATED APPROACH TO CHARACTERIZING BYPASSED OIL IN HETEROGENEOUS AND FRACTURED RESERVOIRS USING PARTITIONING TRACERS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Akhil Datta-Gupta

    2003-08-01

    We explore the use of efficient streamline-based simulation approaches for modeling partitioning interwell tracer tests in hydrocarbon reservoirs. Specifically, we utilize the unique features of streamline models to develop an efficient approach for interpretation and history matching of field tracer response. A critical aspect here is the underdetermined and highly ill-posed nature of the associated inverse problems. We have adopted an integrated approach whereby we combine data from multiple sources to minimize the uncertainty and non-uniqueness in the interpreted results. For partitioning interwell tracer tests, these are primarily the distribution of reservoir permeability and oil saturation distribution. A novel approachmore » to multiscale data integration using Markov Random Fields (MRF) has been developed to integrate static data sources from the reservoir such as core, well log and 3-D seismic data. We have also explored the use of a finite difference reservoir simulator, UTCHEM, for field-scale design and optimization of partitioning interwell tracer tests. The finite-difference model allows us to include detailed physics associated with reactive tracer transport, particularly those related with transverse and cross-streamline mechanisms. We have investigated the potential use of downhole tracer samplers and also the use of natural tracers for the design of partitioning tracer tests. Finally, the behavior of partitioning tracer tests in fractured reservoirs is investigated using a dual-porosity finite-difference model.« less

  18. 78 FR 8538 - Privacy Act of 1974

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... single, streamlined application for consumers to use in applying for eligibility determinations for... subject individual's name (woman's maiden name, if applicable), and SSN (furnishing the SSN is voluntary...

  19. 48 CFR 211.204 - Solicitation provisions and contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... performance requires use of specifications, standards, and data item descriptions that are not listed in the Acquisition Streamlining and Standardization Information System database, use provisions, as appropriate...

  20. 48 CFR 19.1102 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (originally authorized in the Federal Acquisition Streamlining Act of 1994 (Public Law 103-355, Sec. 7102... evaluation adjustment in competitive acquisitions in the authorized NAICS Industry Subsector. (c) Do not use...

  1. Streamlining Traffic Mitigation Fees

    DOT National Transportation Integrated Search

    1999-01-01

    The City of Lacey rewrote the ordinance governing collection of fees to mitigate : development impacts on the transportation system. Previously developers : submitted traffic generation and distribution reports prepared by qualified : traffic enginee...

  2. Streamlining Site Cleanup in New York City

    EPA Pesticide Factsheets

    This joint effort, supported by the New York State Department of Environmental Conservation (NYS DEC), advances the environmental cleanup goals of PlaNYC 2030, the city's comprehensive sustainability plan.

  3. 48 CFR 211.204 - Solicitation provisions and contract clauses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... performance requires use of specifications, standards, and data item descriptions that are not listed in the Acquisition Streamlining and Standardization Information System database, use provisions, as appropriate...

  4. 76 FR 41585 - Regulation and Independent Regulatory Agencies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-14

    ..., competitiveness, and job creation.'' Independent regulatory agencies, no less than executive agencies, should..., streamline, expand, or repeal them in accordance with what has been learned. Such retrospective analyses...

  5. [A project to ameliorate nurses working overtime in psychiatry ward].

    PubMed

    Feng, Yuen-Hsiang; Li, Hsiu-Chen; Fang, Mao-So

    2009-12-01

    The authors found nurses working in psychiatry wards were frequently required to work overtime, with average overtime measuring 85 minutes. After analysis, we found main factors leading to overtime to be late new patient admissions, tardy ward inspections by attending physicians, failure to implement workplace regulations, failure by nurses to implement proper shift transfer procedures, and meeting-related delays. This paper proposes an approach by which average overtime for psychiatry ward nurses may be reduced from 85 to 30 minutes. Based on findings, the researchers adjusted the schedule for ward visits by attending physicians, updated and streamlined workplace regulations, ensured administrative procedures were precisely followed, and updated and streamlined standing orders. Average overtime was reduced from 85 to 25 minutes. This research facilitated a reduction in the amount of overtime registered by nurses.

  6. Hydrodynamic role of longitudinal dorsal ridges in a leatherback turtle swimming

    NASA Astrophysics Data System (ADS)

    Bang, Kyeongtae; Kim, Jooha; Lee, Sang-Im; Choi, Haecheon

    2016-10-01

    Leatherback sea turtles (Dermochelys coriacea) are known to have a superior diving ability and be highly adapted to pelagic swimming. They have five longitudinal ridges on their carapace. Although it was conjectured that these ridges might be an adaptation for flow control, no rigorous study has been performed to understand their hydrodynamic roles. Here we show that these ridges are slightly misaligned to the streamlines around the body to generate streamwise vortices, and suppress or delay flow separation on the carapace, resulting in enhanced hydrodynamic performances during different modes of swimming. Our results suggest that shapes of some morphological features of living creatures, like the longitudinal ridges of the leatherback turtles, need not be streamlined for excellent hydro- or aerodynamic performances, contrary to our common physical intuition.

  7. Hydrodynamic role of longitudinal dorsal ridges in a leatherback turtle swimming

    PubMed Central

    Bang, Kyeongtae; Kim, Jooha; Lee, Sang-Im; Choi, Haecheon

    2016-01-01

    Leatherback sea turtles (Dermochelys coriacea) are known to have a superior diving ability and be highly adapted to pelagic swimming. They have five longitudinal ridges on their carapace. Although it was conjectured that these ridges might be an adaptation for flow control, no rigorous study has been performed to understand their hydrodynamic roles. Here we show that these ridges are slightly misaligned to the streamlines around the body to generate streamwise vortices, and suppress or delay flow separation on the carapace, resulting in enhanced hydrodynamic performances during different modes of swimming. Our results suggest that shapes of some morphological features of living creatures, like the longitudinal ridges of the leatherback turtles, need not be streamlined for excellent hydro- or aerodynamic performances, contrary to our common physical intuition. PMID:27694826

  8. The Zig-zag Instability of Streamlined Bodies

    NASA Astrophysics Data System (ADS)

    Guillet, Thibault; Coux, Martin; Quere, David; Clanet, Christophe

    2017-11-01

    When a floating bluff body, like a sphere, impacts water with a vertical velocity, its trajectory is straight and the depth of its dive increases with its initial velocity. Even though we observe the same phenomenon at low impact speed for axisymmetric streamlined bodies, the trajectory is found to deviate from the vertical when the velocity overcomes a critical value. This instability results from a competition between the destabilizing torque of the lift and the stabilizing torque of the Archimede's force. Balancing these torques yields a prediction on the critical velocity above which the instability appears. This theoretical value is found to depend on the position of the gravity center of the projectile and predicts with a full agreement the behaviour observed in our different experiments. Project funded by DGA.

  9. SUPG Finite Element Simulations of Compressible Flows

    NASA Technical Reports Server (NTRS)

    Kirk, Brnjamin, S.

    2006-01-01

    The Streamline-Upwind Petrov-Galerkin (SUPG) finite element simulations of compressible flows is presented. The topics include: 1) Introduction; 2) SUPG Galerkin Finite Element Methods; 3) Applications; and 4) Bibliography.

  10. Chemical Categories Used to Review New Chemicals under TSCA

    EPA Pesticide Factsheets

    EPA groups Premanufacture Notice (PMN) chemicals with shared chemical and toxicological properties into categories. Establishing these categories has streamlined the process for Agency review of new chemical substances.

  11. ACHP | News

    Science.gov Websites

    Gets Federal Nod The ACHP has entered into Memorandum of Understanding with nine other Federal Agencies , Minnesota, New York, and Pennsylvania in a Memorandum of Understanding (MOU) to enhance and streamline

  12. Inspectors General Streamlining Act

    THOMAS, 113th Congress

    Sen. Coburn, Tom [R-OK

    2014-11-13

    Senate - 11/13/2014 Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  13. Improving Sampling, Analysis, and Data Management for Site Investigation and Cleanup

    EPA Pesticide Factsheets

    The United States Environmental Protection Agency (EPA) supports the adoption of streamlined approaches to sampling, analysis, and data management activities conducted during site assessment, characterization, and cleanup.

  14. Contracting Deployment Customer Guide.

    DTIC Science & Technology

    1996-12-01

    functional managers from the major commands expressed the need to develop a Customer Guide for contingency deployments which would standardize, simplify, and...streamline the support our Contingency Contracting Officers (CCOs) provide to our customers .

  15. Maja Valles

    NASA Image and Video Library

    2012-07-19

    The streamlined island in this image from NASA 2001 Mars Odyssey spacecraft formed within the channel of Maja Valles. The flow of water was deflected by the crater leaving material in the lee of the crater.

  16. Mapping seabed geomorphology in the Inner Hebrides, Scotland; Bathymetric records of ice streaming and retreat

    NASA Astrophysics Data System (ADS)

    Dove, Dayton; Finlayson, Andrew; Bradwell, Tom; Arosio, Riccardo; Howe, John

    2014-05-01

    Approximately 7,000 km² of new bathymetry have been stitched together with onshore airborne radar data, both gridded at 5m resolution, to map and describe the submarine glacial landscape of the Inner Hebrides sector of the former British-Irish Ice Sheet (BIIS). As part of the MAREMAP Project (http://www.maremap.ac.uk), and to build on previous work (Howe et al., 2012), we are using recently acquired swath bathymetry data, collected primarily by the UKHO Civil Hydrography Programme, to characterise the geomorphology, sea-bed sediments, and bedrock geology of the Inner Hebrides region. Mapping has revealed an extensive array of well-preserved glacigenic landforms on the seabed associated with key stages of ice flow and retreat of the BIIS following the Last Glacial Maximum. On multiple submarine rock platforms and within overdeepened troughs, diverse assemblages of glacially streamlined landforms are present, forming a geomorphic continuum between rock drumlins and mega-flutes. Superimposed streamlined bedforms indicate different phases of fast flow at the ice sheet bed, and the convergence of flow sets suggest that ice sheet flow was organised into faster flowing topographically controlled corridors. Across the region, the streamlined landforms occur within a geographically controlled zone, semi-independent of the underlying geology. This is consistent with the onset zone of the Hebrides Ice Stream, as previously postulated (Howe et al., 2012). Submarine moraine ridges are observed widely across the survey area: within sea lochs, atop rock platforms and superimposed on glacially streamlined bedforms, as well as pinned to topographic highs (i.e. islands). Some retreat patterns reveal clear glacial recession towards respective catchments, while others are more ambiguous and are the focus of ongoing work. The bathymetry data notably reveal more geomorphic evidence of glaciation than adjacent land records, thus providing the opportunity to reassess onshore mapping where clear offshore examples may provide insights into poorly understood terrestrial geological and geomorphological features. And importantly, these new data provide the opportunity to greatly improve offshore geology maps of the region, which are in increasing demand by governmental, commercial, and conservation groups.

  17. Ringing in an HNBody Upgrade

    NASA Astrophysics Data System (ADS)

    Rimlinger, Thomas; Hamilton, Douglas; Hahn, Joseph M.

    2017-06-01

    We are in the process of developing a useful extension to the N-body integrator HNBody (Rauch & Hamilton 2002), enabling it to simulate a viscous, self-gravitating ring orbiting an oblate body. Our algorithm follows that used in the symplectic integrator epi_int (Hahn & Spitale 2013), in which the ring is simulated as many (~100) interacting, elliptic, confocal streamlines. This idea was first introduced in an analytic context by Goldreich & Tremaine (1979) and enabled rapid progress in the theory of ring evolution; since then, such discretization has been standard in the literature. While we adopt epi_int’s streamline formalism, we nevertheless improve upon its design in several ways. Epi_int uses epicyclic elements in its drift step; approximating these elements introduces small, systematic errors that build up with time. We sidestep this problem by instead using the more traditional Keplerian osculating elements. In addition, epi_int uses several particles per wire to effectively calculate the inter-gravitational forces everywhere along each streamline. We replicate this ability but can often gain a speed boost by using a single tracer particle per streamline; while this restricts us to simulating rings dominated by the m = 1 mode, this is typical of most observed narrow eccentric ringlets. We have also extended epi_int’s two dimensional algorithm into 3D. Finally, whereas epi_int is written in IDL, HNBody is written in C, which yields considerably faster integrations.Braga-Ribas et al. (2014) reported a set of narrow rings orbiting the Centaur Chariklo, but neither their investigation nor that of Pan & Wu (2016) yielded a satisfactory origin and evolution scenario. Eschewing the assumption that such rings must be short-lived, we instead argue (as in Rimlinger et al. 2016) that sufficiently eccentric rings can self-confine for hundreds of millions of years while circularizing. In this case, Chariklo may have formed rings as a KBO. We are working towards demonstrating both the feasibility of this theory and the utility of the HNBody extension by using it to simulate such a ring around Chariklo.

  18. Redesign of employee cafeteria increases efficiency, satisfaction.

    PubMed

    Snook, I D; Levitsky, S E

    1980-12-01

    By streamlining the menu selection, layout, and operation of its employee cafeteria, a hospital was able to improve employee satisfaction with the service and reallocate needed resources to its inpatient food service.

  19. Lean and Information Technology Toolkit

    EPA Pesticide Factsheets

    The Lean and Information Technology Toolkit is a how-to guide which provides resources to environmental agencies to help them use Lean Startup, Lean process improvement, and Agile tools to streamline and automate processes.

  20. Assessing Contractor Capabilities for Streamlined Site Investigations

    EPA Pesticide Factsheets

    The purpose of this document is to familiarize and encourage brownfields decision makers to investigate and employ innovative methods for characterizing their sites, to assist brownfields decision makers in assessing contractors' capabilities.

  1. Breaking Ground.

    ERIC Educational Resources Information Center

    American School & University, 1998

    1998-01-01

    Explains the importance of using geothermal systems to reduce energy costs and improve heating and cooling in multipurpose schools. What geothermal systems are and their benefits in simplifying the school infrastructure and streamlining operating costs are highlighted. (GR)

  2. Streamlining Services for Older Veterans Act

    THOMAS, 113th Congress

    Sen. Manchin, Joe, III [D-WV

    2014-02-03

    Senate - 02/03/2014 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  3. Streamlining Services for Older Veterans Act

    THOMAS, 112th Congress

    Sen. Manchin, Joe, III [D-WV

    2012-09-21

    Senate - 09/21/2012 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  4. A Simple Water Channel

    ERIC Educational Resources Information Center

    White, A. S.

    1976-01-01

    Describes a simple water channel, for use with an overhead projector. It is run from a water tap and may be used for flow visualization experiments, including the effect of streamlining and elementary building aerodynamics. (MLH)

  5. Agile

    NASA Technical Reports Server (NTRS)

    Trimble, Jay Phillip

    2013-01-01

    This is based on a previous talk on agile development. Methods for delivering software on a short cycle are described, including interactions with the customer, the affect on the team, and how to be more effective, streamlined and efficient.

  6. Updated Panel-Method Computer Program

    NASA Technical Reports Server (NTRS)

    Ashby, Dale L.

    1995-01-01

    Panel code PMARC_12 (Panel Method Ames Research Center, version 12) computes potential-flow fields around complex three-dimensional bodies such as complete aircraft models. Contains several advanced features, including internal mathematical modeling of flow, time-stepping wake model for simulating either steady or unsteady motions, capability for Trefftz computation of drag induced by plane, and capability for computation of off-body and on-body streamlines, and capability of computation of boundary-layer parameters by use of two-dimensional integral boundary-layer method along surface streamlines. Investigators interested in visual representations of phenomena, may want to consider obtaining program GVS (ARC-13361), General visualization System. GVS is Silicon Graphics IRIS program created to support scientific-visualization needs of PMARC_12. GVS available separately from COSMIC. PMARC_12 written in standard FORTRAN 77, with exception of NAMELIST extension used for input.

  7. "Birth Control can Easily Take a Back Seat": Challenges Providing IUDs in Community Health Care Settings.

    PubMed

    Biggs, M Antonia; Kaller, Shelly; Harper, Cynthia C; Freedman, Lori; Mays, Aisha R

    2018-01-01

    To assess community health centers' (CHCs) capacity to offer streamlined intrauterine devices (IUDs) services. Prior to implementing a contraceptive training project, we surveyed health care staff (N=97) from 11 CHC sites that offer IUDs onsite. Twenty interviews with clinicians explored more deeply their challenges offering IUDs in the CHC setting. Most practices required multiple visits for IUD placement, most (66%) clinician survey respondents had placed an IUD and 19% had placed an IUD as emergency contraception. Need for screening tests, scheduling challenges, pressures to meet patient quotas, and lack of priority given to women's health hindered streamlined IUD provision. Although access to IUDs has increased, significant barriers to provision in CHC settings persist. Clinic policies may need to address a variety of system and provider-level barriers to meet the needs of patients.

  8. Microfluidic-Mass Spectrometry Interfaces for Translational Proteomics.

    PubMed

    Pedde, R Daniel; Li, Huiyan; Borchers, Christoph H; Akbari, Mohsen

    2017-10-01

    Interfacing mass spectrometry (MS) with microfluidic chips (μchip-MS) holds considerable potential to transform a clinician's toolbox, providing translatable methods for the early detection, diagnosis, monitoring, and treatment of noncommunicable diseases by streamlining and integrating laborious sample preparation workflows on high-throughput, user-friendly platforms. Overcoming the limitations of competitive immunoassays - currently the gold standard in clinical proteomics - μchip-MS can provide unprecedented access to complex proteomic assays having high sensitivity and specificity, but without the labor, costs, and complexities associated with conventional MS sample processing. This review surveys recent μchip-MS systems for clinical applications and examines their emerging role in streamlining the development and translation of MS-based proteomic assays by alleviating many of the challenges that currently inhibit widespread clinical adoption. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  9. Calculation of inviscid surface streamlines and heat transfer on shuttle type configurations. Part 2: Description of computer program

    NASA Technical Reports Server (NTRS)

    Dejarnette, F. R.; Jones, M. H.

    1971-01-01

    A description of the computer program used for heating rate calculation for blunt bodies in hypersonic flow is given. The main program and each subprogram are described by defining the pertinent symbols involved and presenting a detailed flow diagram and complete computer program listing. Input and output parameters are discussed in detail. Listings are given for the computation of heating rates on (1) a blunted 15 deg half-angle cone at 20 deg incidence and Mach 10.6, (2) a blunted 70 deg slab delta wing at 10 deg incidence and Mach 8, and (3) the HL-10 lifting body at 20 deg incidence and Mach 10. In addition, the computer program output for two streamlines on the blunted 15 deg half-angle cone is listed. For Part 1, see N71-36186.

  10. Streamlining Software Aspects of Certification: Report on the SSAC Survey

    NASA Technical Reports Server (NTRS)

    Hayhurst, Kelly J.; Dorsey, Cheryl A.; Knight, John C.; Leveson, Nancy G.; McCormick, G. Frank

    1999-01-01

    The aviation system now depends on information technology more than ever before to ensure safety and efficiency. To address concerns about the efficacy of software aspects of the certification process, the Federal Aviation Administration (FAA) began the Streamlining Software Aspects of Certification (SSAC) program. The SSAC technical team was commissioned to gather data, analyze results, and propose recommendations to maximize efficiency and minimize cost and delay, without compromising safety. The technical team conducted two public workshops to identify and prioritize software approval issues, and conducted a survey to validate the most urgent of those issues. The SSAC survey, containing over two hundred questions about the FAA's software approval process, reached over four hundred industry software developers, aircraft manufacturers, and FAA designated engineering representatives. Three hundred people responded. This report presents the SSAC program rationale, survey process, preliminary findings, and recommendations.

  11. Quantum mechanical streamlines. I - Square potential barrier

    NASA Technical Reports Server (NTRS)

    Hirschfelder, J. O.; Christoph, A. C.; Palke, W. E.

    1974-01-01

    Exact numerical calculations are made for scattering of quantum mechanical particles hitting a square two-dimensional potential barrier (an exact analog of the Goos-Haenchen optical experiments). Quantum mechanical streamlines are plotted and found to be smooth and continuous, to have continuous first derivatives even through the classical forbidden region, and to form quantized vortices around each of the nodal points. A comparison is made between the present numerical calculations and the stationary wave approximation, and good agreement is found between both the Goos-Haenchen shifts and the reflection coefficients. The time-independent Schroedinger equation for real wavefunctions is reduced to solving a nonlinear first-order partial differential equation, leading to a generalization of the Prager-Hirschfelder perturbation scheme. Implications of the hydrodynamical formulation of quantum mechanics are discussed, and cases are cited where quantum and classical mechanical motions are identical.

  12. US Topo Maps 2014: Program updates and research

    USGS Publications Warehouse

    Fishburn, Kristin A.

    2014-01-01

    The U. S. Geological Survey (USGS) US Topo map program is now in year two of its second three-year update cycle. Since the program was launched in 2009, the product and the production system tools and processes have undergone enhancements that have made the US Topo maps a popular success story. Research and development continues with structural and content product enhancements, streamlined and more fully automated workflows, and the evaluation of a GIS-friendly US Topo GIS Packet. In addition, change detection methodologies are under evaluation to further streamline product maintenance and minimize resource expenditures for production in the future. The US Topo map program will continue to evolve in the years to come, providing traditional map users and Geographic Information System (GIS) analysts alike with a convenient, freely available product incorporating nationally consistent data that are quality assured to high standards.

  13. Investigating the effects of streamline-based fiber tractography on matrix scaling in brain connective network.

    PubMed

    Jan, Hengtai; Chao, Yi-Ping; Cho, Kuan-Hung; Kuo, Li-Wei

    2013-01-01

    Investigating the brain connective network using the modern graph theory has been widely applied in cognitive and clinical neuroscience research. In this study, we aimed to investigate the effects of streamline-based fiber tractography on the change of network properties and established a systematic framework to understand how an adequate network matrix scaling can be determined. The network properties, including degree, efficiency and betweenness centrality, show similar tendency in both left and right hemispheres. By employing the curve-fitting process with exponential law and measuring the residuals, the association between changes of network properties and threshold of track numbers is found and an adequate range of investigating the lateralization of brain network is suggested. The proposed approach can be further applied in clinical applications to improve the diagnostic sensitivity using network analysis with graph theory.

  14. Streakline flow visualization study of a horseshoe vortex in a large-scale, two-dimensional turbine stator cascade

    NASA Technical Reports Server (NTRS)

    Gaugler, R. E.; Russell, L. M.

    1980-01-01

    Neutrally buoyant helium-filled bubbles were observed as they followed the streamlines in a horseshoe vortex system around the vane leading edge in a large-scale, two-dimensional, turbine stator cascade. Bubbles were introduced into the endwall boundary layer through a slot upstream of the vane leading edge. The paths of the bubbles were recorded photographically as streaklines on 16-mm movie film. Individual frames from the film have been selected, and overlayed to show the details of the horseshoe vortex around the leading edge. The transport of the vortex across the passage near the leading edge is clearly seen when compared to the streaks formed by bubbles carried in the main stream. Limiting streamlines on the endwall surface were traced by the flow of oil drops.

  15. Increasing productivity by reducing average length of stay (ALOS) in Apollo Gleneagles Hospitals, Kolkata, India.

    PubMed

    Kar, Sujoy; Basu, Rupali

    2013-01-01

    Reduction of ALOS in the hospital through streamlined processes with validation for standardized work such as clinical pathways. The implementation of barcoding and streamlining laboratories with interface solutions has reduced the cycle time for the diagnostic areas. The long standing cases over seven days provided a trigger for the Medical Board, which helped in multidisciplinary care of these patients. Cohort of patients in respective wards according to discipline for almost 80% of patients have improved nursing and other paramedical services and had a definite impact on ALOS and other outcomes. Finally, the organization had a benefit of nearly USD 0.9 million for a period of nine months during this study. The organization has carried on with the benefits of the ALOS reduction and currently has reduced ALOS to 4.5 days.

  16. An evaluation in a modern wind tunnel of the transonic adaptive wall adjustment strategy developed by NPL in the 1940's

    NASA Technical Reports Server (NTRS)

    Lewis, M. C.

    1988-01-01

    The first documented wind tunnel employing a flexible walled test section for the purpose of eliminating wall interference was constructed in England by the National Physical Laboratory (NPL) during the late 1930's. The tunnel was transonic and designed for two-dimensional testing. In an attempt to eliminate the top and bottom wall interference effects on the model NPL developed a strategy to adjust two flexible walls to streamlined shapes. This report covers an evaluation of the NPL wall adjustment strategy in a modern wind tunnel, e.g., the Transonic Self-Streamlining Wind Tunnel (TSWT) at the University of Southampton, England. The evaluation took the form of performance comparisons with other modern strategies which have been developed for use in, and proven in, the TSWT.

  17. Simplified hydrodynamic analysis on the general shape of the hill charts of Francis turbines using shroud-streamline modeling

    NASA Astrophysics Data System (ADS)

    Iliev, I.; Trivedi, C.; Dahlhaug, O. G.

    2018-06-01

    The paper presents a simplified one-dimensional calculation of the efficiency hill-chart for Francis turbines, based on the velocity triangles at the inlet and outlet of the runner’s blade. Calculation is done for one streamline, namely the shroud streamline in the meridional section, where an efficiency model is established and iteratively approximated in order to satisfy the Euler equation for turbomachines at a wide operating range around the best efficiency point (BEP). Using the presented method, hill charts are calculated for one splitter-bladed Francis turbine runner and one Reversible Pump-Turbine (RPT) runner operated in the turbine mode. Both turbines have similar and relatively low specific speeds of nsQ = 23.3 and nsQ = 27, equal inlet and outlet diameters and are designed to fit in the same turbine rig for laboratory measurements (i.e. spiral casing and draft tube are the same). Calculated hill charts are compared against performance data obtained experimentally from model tests according to IEC standards for both turbines. Good agreement between theoretical and experimental results is observed when comparing the shapes of the efficiency contours in the hill-charts. The simplified analysis identifies the design parameters that defines the general shape and inclination of the turbine’s hill charts and, with some additional improvements in the loss models used, it can be used for quick assessment of the performance at off-design conditions during the design process of hydraulic turbines.

  18. Predicting planning performance from structural connectivity between left and right mid-dorsolateral prefrontal cortex: moderating effects of age during postadolescence and midadulthood.

    PubMed

    Kaller, Christoph P; Reisert, Marco; Katzev, Michael; Umarova, Roza; Mader, Irina; Hennig, Jürgen; Weiller, Cornelius; Köstering, Lena

    2015-04-01

    Complex cognitive abilities such as planning are known to critically rely on activity of bilateral mid-dorsolateral prefrontal cortex (mid-dlPFC). However, the functional relevance of the structural connectivity between left and right mid-dlPFC is yet unknown. Here, we applied global tractography to derive streamline counts as estimates of the structural connectivity between mid-dlPFC homologs and related it to planning performance in the Tower of London task across early to midadulthood, assuming a moderating effect of age. Multiple regression analyses with interaction effects revealed that streamline counts between left and right mid-dlPFC were negatively associated with planning performance specifically in early postadolescence. From the fourth life decade on, there was a trend for a reversed, positive association. These differential findings were corroborated by converging results from fractional anisotropy and white-matter density estimates in the genu of the corpus callosum where fibers connecting mid-dlPFC homologs traversed. Moreover, the results for streamline counts were regionally specific, marking the strength of mid-dlPFC connectivity as critical in predicting interindividual differences in planning performance across different stages of adulthood. Taken together, present findings provide first evidence for nonadditive effects of age on the relation between complex cognitive abilities and the structural connectivity of mid-dlPFC homologs. © The Author 2013. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  19. Recirculating, passive micromixer with a novel sawtooth structure.

    PubMed

    Nichols, Kevin P; Ferullo, Julia R; Baeumner, Antje J

    2006-02-01

    A microfluidic device capable of recirculating nano to microlitre volumes in order to efficiently mix solutions is described. The device consists of molded polydimethyl siloxane (PDMS) channels with pressure inlet and outlet holes sealed by a glass lid. Recirculation is accomplished by a repeatedly reciprocated flow over an iterated sawtooth structure. The sawtooth structure serves to change the fluid velocity of individual streamlines differently depending on whether the fluid is flowing backwards or forward over the structure. Thus, individual streamlines can be accelerated or decelerated relative to the other streamlines to allow sections of the fluid to interact that would normally be linearly separated. Low Reynolds numbers imply that the process is reversible, neglecting diffusion. Computer simulations were carried out using FLUENT. Subsequently, fluorescent indicators were employed to experimentally verify these numerical simulations of the recirculation principal. Finally, mixing of a carboxyfluorescein labeled DMSO plug with an unlabeled DMSO plug across an immiscible hydrocarbon plug was investigated. At cycling rates of 1 Hz across five sawtooth units, the time was recorded to reach steady state in the channels, i.e. until both DMSO plugs had the same fluorescence intensity. In the case of the sawtooth structures, steady state was reached five times faster than in channels without sawtooth structures, which verified what would be expected based on numerical simulations. The microfluidic mixer is unique due to its versatility with respect to scaling, its potential to also mix solutions containing small particles such as beads and cells, and its ease of fabrication and use.

  20. Visualizing whole-brain DTI tractography with GPU-based Tuboids and LoD management.

    PubMed

    Petrovic, Vid; Fallon, James; Kuester, Falko

    2007-01-01

    Diffusion Tensor Imaging (DTI) of the human brain, coupled with tractography techniques, enable the extraction of large-collections of three-dimensional tract pathways per subject. These pathways and pathway bundles represent the connectivity between different brain regions and are critical for the understanding of brain related diseases. A flexible and efficient GPU-based rendering technique for DTI tractography data is presented that addresses common performance bottlenecks and image-quality issues, allowing interactive render rates to be achieved on commodity hardware. An occlusion query-based pathway LoD management system for streamlines/streamtubes/tuboids is introduced that optimizes input geometry, vertex processing, and fragment processing loads, and helps reduce overdraw. The tuboid, a fully-shaded streamtube impostor constructed entirely on the GPU from streamline vertices, is also introduced. Unlike full streamtubes and other impostor constructs, tuboids require little to no preprocessing or extra space over the original streamline data. The supported fragment processing levels of detail range from texture-based draft shading to full raycast normal computation, Phong shading, environment mapping, and curvature-correct text labeling. The presented text labeling technique for tuboids provides adaptive, aesthetically pleasing labels that appear attached to the surface of the tubes. Furthermore, an occlusion query aggregating and scheduling scheme for tuboids is described that reduces the query overhead. Results for a tractography dataset are presented, and demonstrate that LoD-managed tuboids offer benefits over traditional streamtubes both in performance and appearance.

  1. An Experimental Investigation of the Laminar Flamelet Concept for Soot Properties

    NASA Technical Reports Server (NTRS)

    Diez, F. J.; Aalburg, C.; Sunderland, P. B.; Urban, D. L.; Yuan, Z.-G.; Faeth, G. M.

    2007-01-01

    The soot properties of round, nonbuoyant, laminar jet diffusion flames are described, based on experiments at microgravity carried out on orbit during three flights of the Space Shuttle Columbia, (Flights STS-83, 94 and 107). Experimental conditions included ethylene- and propane-fueled flames burning in still air at an ambient temperature of 300 K and ambient pressures of 35-100 kPa. Measurements included soot volume fraction distributions using deconvoluted laser extinction imaging, and soot temperature distributions using deconvoluted multiline emission imaging. Flowfield modeling based on the work of Spalding is presented. The present work explores whether soot properties of these flames are universal functions of mixture fraction, i.e., whether they satisfy soot state relationships. Measurements are presented, including radiative emissions and distributions of soot temperature and soot volume fraction. It is shown that most of the volume of these flames is bounded by the dividing streamline and thus should follow residence time state relationships. Most streamlines from the fuel supply to the surroundings are found to exhibit nearly the same maximum soot volume fraction and temperature. The radiation intensity along internal streamlines also is found to have relatively uniform values. Finally, soot state relationships were observed, i.e., soot volume fraction was found to correlate with estimated mixture fraction for each fuel/pressure selection. These results support the existence of soot property state relationships for steady nonbuoyant laminar diffusion flames, and thus in a large class of practical turbulent diffusion flames through the application of the laminar flamelet concept.

  2. Bioprofiling of unknown antibiotics in herbal extracts: Development of a streamlined direct bioautography using Bacillus subtilis linked to mass spectrometry.

    PubMed

    Jamshidi-Aidji, Maryam; Morlock, Gertrud E

    2015-11-13

    Working in the field of profiling and identification of bioactive compounds in herbal extracts is faced with the challenge that common chromatographic methods do not directly link to bioactive compounds. Direct bioautography, the combination of TLC/HPTLC with bioassays, linked to structure elucidating techniques is demonstrated to overcome this challenge. The combination of TLC and Bacillus subtilis bioassay was already demonstrated to detect the antibiotics in samples. However, previous studies in this field were faced with some challenges, like being time-consuming, leading not to a homogenous plate background or being restricted to a non-acidic mobile phase. In this study, these aspects were investigated and a streamlined HPTLC-B. subtilis bioassay was developed that generated a homogenous plate background, which was crucial to yield a good baseline for biodensitometry. Two commonly used broths for B. subtilis and a self-designed medium were compared with regard to their capability of detection and baseline noise. The workflow developed allowed the use of acidic mobile phases for the first time. To prove this, 20 herbal extracts were screened for antimicrobial substances developed in parallel with an acidic mobile phase. The main antimicrobial substance in Salvia officinalis tincture detected was further characterized by microchemical reactions, Aliivibrio fischeri, β-glucosidase and acetylcholinesterase (bio)assays as well as mass spectrometry. Scientists looking for new herbal-based medicine may benefit from this time-saving and streamlined bioactivity profiling. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Streamlined genetic education is effective in preparing women newly diagnosed with breast cancer for decision making about treatment-focused genetic testing: a randomized controlled noninferiority trial.

    PubMed

    Quinn, Veronica F; Meiser, Bettina; Kirk, Judy; Tucker, Kathy M; Watts, Kaaren J; Rahman, Belinda; Peate, Michelle; Saunders, Christobel; Geelhoed, Elizabeth; Gleeson, Margaret; Barlow-Stewart, Kristine; Field, Michael; Harris, Marion; Antill, Yoland C; Cicciarelli, Linda; Crowe, Karen; Bowen, Michael T; Mitchell, Gillian

    2017-04-01

    Increasingly, women newly diagnosed with breast cancer are being offered treatment-focused genetic testing (TFGT). As the demand for TFGT increases, streamlined methods of genetic education are needed. In this noninferiority trial, women aged <50 years with either a strong family history (FH+) or other features suggestive of a germ-line mutation (FH-) were randomized before definitive breast cancer surgery to receive TFGT education either as brief written materials (intervention group (IG)) or during a genetic counseling session at a familial cancer clinic (usual-care group (UCG)). Women completed self-report questionnaires at four time points over 12 months. A total of 135 women were included in the analysis, all of whom opted for TFGT. Decisional conflict about TFGT choice (primary outcome) was not inferior in the IG compared with the UCG (noninferiority margin of -10; mean difference = 2.45; 95% confidence interval -2.87-7.76; P = 0.36). Costs per woman counseled in the IG were significantly lower (AUD$89) compared with the UCG (AUD$173; t(115) = 6.02; P < 0.001). A streamlined model of educating women newly diagnosed with breast cancer about TFGT seems to be a cost-effective way of delivering education while ensuring that women feel informed and supported in their decision making, thus freeing resources for other women to access TFGT.Genet Med 19 4, 448-456.

  4. A streamlined failure mode and effects analysis.

    PubMed

    Ford, Eric C; Smith, Koren; Terezakis, Stephanie; Croog, Victoria; Gollamudi, Smitha; Gage, Irene; Keck, Jordie; DeWeese, Theodore; Sibley, Greg

    2014-06-01

    Explore the feasibility and impact of a streamlined failure mode and effects analysis (FMEA) using a structured process that is designed to minimize staff effort. FMEA for the external beam process was conducted at an affiliate radiation oncology center that treats approximately 60 patients per day. A structured FMEA process was developed which included clearly defined roles and goals for each phase. A core group of seven people was identified and a facilitator was chosen to lead the effort. Failure modes were identified and scored according to the FMEA formalism. A risk priority number,RPN, was calculated and used to rank failure modes. Failure modes with RPN > 150 received safety improvement interventions. Staff effort was carefully tracked throughout the project. Fifty-two failure modes were identified, 22 collected during meetings, and 30 from take-home worksheets. The four top-ranked failure modes were: delay in film check, missing pacemaker protocol/consent, critical structures not contoured, and pregnant patient simulated without the team's knowledge of the pregnancy. These four failure modes had RPN > 150 and received safety interventions. The FMEA was completed in one month in four 1-h meetings. A total of 55 staff hours were required and, additionally, 20 h by the facilitator. Streamlined FMEA provides a means of accomplishing a relatively large-scale analysis with modest effort. One potential value of FMEA is that it potentially provides a means of measuring the impact of quality improvement efforts through a reduction in risk scores. Future study of this possibility is needed.

  5. 77 FR 60910 - Approval and Promulgation of Air Quality Implementation Plans; Pennsylvania; Streamlining...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-05

    ..., the Commenter asserts that, ``It defies common understanding of fairness to push burdens away from the... as establishing deadlines on both parties eliminates potentially open ended, back-and-forth...

  6. Smart Sectors Program: Best Practices in Permitting Profile

    EPA Pesticide Factsheets

    Smart Sectors profile about a streamlined permitting success story between South Carolina Department of Health and Environmental Control, US Army Corps of Engineers, EPA, non-governmental organizations, and a major aircraft manufacturer in Charleston, SC.

  7. State transportation liaison funded positions study

    DOT National Transportation Integrated Search

    2009-10-01

    The Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users (SAFETEA-LU), which was signed into law in August 2005, contained several provisions focused on streamlining the environmental review process. One of these provi...

  8. Streamlining the SIP Process

    EPA Pesticide Factsheets

    EPA collaborated with the The National Association of Clean Air Agencies (NACAA/ECOs) SIP Reform Work Group to minimize federal and state burden in developing SIPs, but ensure the plans effectiveness in complying with the Clean Air Act.

  9. Try These Time Management Tips.

    ERIC Educational Resources Information Center

    Bimrose, Jack J.

    1987-01-01

    Offers 12 time management tips for harried school administrators, including using a personal calendar, calling five-minute meetings with secretaries, mail-sorting, delegating or declining certain tasks, controlling visitors, screening phone calls, streamlining meetings, and other ideas. (MLH)

  10. Boundary-layer processes: key findings from MATERHORN-X field campaigns

    NASA Astrophysics Data System (ADS)

    Di Sabatino, Silvana; Leo, Laura S.; Pardyjak, Eric R.; Fernando, Harindra JS

    2017-04-01

    Understanding of atmospheric boundary-layer processes in complex terrain continues to be an active area of research considering its profound implications on numerical weather prediction (WP). It is largely recognized that nocturnal circulation, non-stationary processes involved in evening and morning transitions as well gusty conditions near mountains are poorly captured by current WP models. The search for novel understanding of boundary-layer phenomena especially in critical conditions for WP models has been one of the goals of the interdisciplinary Mountain Terrain Atmospheric Modeling and Observations (MATERHORN) program (2011-2016). The program developed with four main pillars: modelling (MATERHORN-M), experiments (MATERHORN-X), technology (MATERHORN-T), and parameterizations (MATERHORN-P), all synergistically working to meet new scientific challenges, address them effectively through dedicated field and laboratory studies, and transfer the acquired knowledge for model improvements. Specifically, MATERHORN-X is at the core of the MATERHORN program. It was built upon two major field experiments carried out in 31 September-October 2012 and in May 2013 at the Granite Mountain Atmospheric Science Testbed 32 (GMAST) of the Dugway Proving Ground (DPG). In this talk we will focus on results of data analyses from MATERHORN-X with emphasis on several aspects of the nocturnal circulation under low synoptic forcing when stable stratification occurs. The first part of the talk will discuss the evolution of nocturnal flows including both evening transitions on slopes and valleys as well as the occurrence of isolated flow bursts under very stable conditions. As far as the former is concerned we report on our latest understanding of mechanisms leading to evening transitions (e.g. shadow front, slab flow, and transitional front). As far as the latter is concerned, it is hypothesized that a link exists between isolated bursts in turbulent kinetic energy and low-level jets structure, a feature which is commonly found in the first 50-100 m from the ground. The second part of the talk will discuss the interaction between an isolated hill and an approaching (undisturbed) stably-stratified flow with emphasis on the dividing streamline concept. The hill was located northwest of and close to the Granite Mountain, and was approximately 60m in height. A suite of (smoke) flow-visualization, remote sensing and in-situ measurement assets were deployed. At small Froude numbers (Fr<1), a stratified flow approaching the hill either possesses sufficient kinetic energy to pass over the summit or else flows around the sides, with the dividing streamline separating the two scenarios. By applying a logarithmic approach velocity profile to the well-known Sheppard's formula based on simple energetics, an explicit representation for the dividing streamline height was derived and a new set of parameters were identified to determine the dividing streamline height. The analysis shows that there will always be a dividing streamline for real atmospheric stratified shear flows. This has relevant implications for modelling air-flow and dispersion in mountainous regions.

  11. Shalbatana/Simud Vallis Junction

    NASA Image and Video Library

    2003-01-11

    The sinuous channels and streamlined islands at the junction of Shalbatana and Simud Vallis, seen in this NASA Mars Odyssey image, present an erosional history of the catastrophic floods that scoured the Martian surface hundreds of millions of years ago.

  12. Alternative Fuels Data Center: California Ramps Up Biofuels Infrastructure

    Science.gov Websites

    providers are able to offer station owners turn-key packages, complete with tanks and dispensers, with a , and helping to streamline permitting processes. Today, fuel providers are able to offer station owners

  13. Approaches to Streamline Air Permitting for Combined Heat and Power: Permits by Rule and General Permits

    EPA Pesticide Factsheets

    This factsheet provides information about permit by rule (PBR) and general permit (GP) processes, including the factors that contributed to their development and lessons learned from their implementation.

  14. Streamlined project closeout for construction at KYTC.

    DOT National Transportation Integrated Search

    2017-09-01

    Project closeout is the period between the end of construction and when a contract is finalized. During closeout, resources are held in encumbered funds intended for the project and in the contractors bonding capacity. Although the Kentucky Transp...

  15. Visualization case studies : a summary of three transportation applications of visualization

    DOT National Transportation Integrated Search

    2007-11-30

    The three case studies presented in "Visualization Case Studies" are intended to be helpful to transportation agencies in identifying effective techniques for enhancing and streamlining the project development process, including public outreach activ...

  16. Heuristics Reasoning in Diagnostic Judgment.

    ERIC Educational Resources Information Center

    O'Neill, Eileen S.

    1995-01-01

    Describes three heuristics--short-cut mental strategies that streamline information--relevant to diagnostic reasoning: accessibility, similarity, and anchoring and adjustment. Analyzes factors thought to influence heuristic reasoning and presents interventions to be tested for nursing practice and education. (JOW)

  17. 76 FR 13420 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ... responsible for making award decisions. To streamline the collection, selection, and assignment of expert... or by fax to 202-395-6974. Please direct all correspondence to the ``attention of the desk officer...

  18. 76 FR 75825 - Streamlining Inherited Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-05

    ... submitting comments. Mail: Research, Markets & Regulations Division, Bureau of Consumer Financial Protection... Lieu of Mail: Research, Markets & Regulations Division, Bureau of Consumer Financial Protection, 1700 G..., Counsel, Research, Markets & Regulations Division, Bureau of Consumer Financial Protection, (202) 453-7700...

  19. Design and Build Approaches for Green Streets

    EPA Pesticide Factsheets

    This page serves to discuss the concept behind G3's innovative design build strategy. Design build offers a more comprehensive and streamlined approach to project construction and management compared to my traditional methods and is highly encouraged

  20. Guidance on Streamlining the SIP Process

    EPA Pesticide Factsheets

    EPA collaborated with the The National Association of Clean Air Agencies (NACAA/ECOs) SIP Reform Work Group to minimize federal and state burden in developing SIPs, but ensure the plans effectiveness in complying with the Clean Air Act.

  1. Streamlining project delivery through risk analysis.

    DOT National Transportation Integrated Search

    2015-08-01

    Project delivery is a significant area of concern and is subject to several risks throughout Plan Development : Process (PDP). These risks are attributed to major areas of project development, such as environmental : analysis, right-of-way (ROW) acqu...

  2. 3 CFR 13579 - Executive Order 13579 of July 11, 2011. Regulation and Independent Regulatory Agencies

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., streamline, expand, or repeal them in accordance with what has been learned. Such retrospective analyses... agency's regulatory program more effective or less burdensome in achieving the regulatory objectives. Sec...

  3. DOT's Restructuring - Limited Progress in Streamlining Field Office Structure

    DOT National Transportation Integrated Search

    1998-04-30

    The report characterizes two ongoing efforts in the Department involving our : analysis of opportunities to collocate field offices on an intermodal basis, and : FHWA's examination of its regional office structure. Although many aspects of : our effo...

  4. Environment.

    ERIC Educational Resources Information Center

    White, Gilbert F.

    1980-01-01

    Presented are perspectives on the emergence of environmental problems. Six major trends in scientific thinking are identified including: holistic approaches to examining environments, life support systems, resource management, risk assessment, streamlined methods for monitoring environmental change, and emphasis on the global framework. (Author/SA)

  5. Streamlining air quality models in Alabama

    DOT National Transportation Integrated Search

    2004-07-01

    This report documents a research project sponsored by the Alabama Department of Transportation (ALDOT) and conducted by the University of Central Florida (UCF) and the University of Alabama at Birmingham (UAB) to develop a user-friendly, Windows vers...

  6. Improving transit equity, streamlining operations : technologies that benefit the transportation disadvantaged

    DOT National Transportation Integrated Search

    2006-01-01

    This illustrates some of the ways in which technology has improved the ability of transportation disadvantaged individuals to use public transit. Some benefits offered include more efficient coordination among service providers, system flexibility, t...

  7. Streamlining Field Data Collection With Mobile Apps

    NASA Astrophysics Data System (ADS)

    Camp, Reid J.; Wheaton, Joseph M.

    2014-12-01

    Fieldwork is a major component of nearly every geoscience discipline. Over the past 3 decades, scientists have amassed an array of specialized instrumentation and equipment to help them measure and monitor a staggering assortment of geophysical phenomena.

  8. Design of Multistage Axial-Flow Compressors

    NASA Technical Reports Server (NTRS)

    Crouse, J. E.; Gorrell, W. T.

    1983-01-01

    Program developed for computing aerodynamic design of multistage axialflow compressor and associated blading geometry input for internal flow analysis. Aerodynamic solution gives velocity diagrams on selected streamlines of revolution at blade row edges. Program written in FORTRAN IV.

  9. Job titles need to reflect modern times and go gender neutral.

    PubMed

    Foster, Sam

    2018-04-12

    The chance to update nursing and midwifery titles can not only help streamline the confusing array of roles, but ensure that trusts employ bona fide registrants, suggests Sam Foster, Chief Nurse, Oxford University Hospitals.

  10. Results of a State-Wide Evaluation of “Paperwork Burden” in Addiction Treatment

    PubMed Central

    Carise, Deni; Love, Meghan; Zur, Julia; McLellan, A. Thomas; Kemp, Jack

    2009-01-01

    This article chronicles three steps taken by research, clinical and state staff towards assessing, evaluating and streamlining clinical and administrative paperwork at all public outpatient addiction treatment programs in 1 state. The first step was an accounting of all paperwork requirements at each program. Step two included the development of time estimates for the paperwork requirements, synthesis of information across sites, providing written evaluation of the need, utility and redundancy of all forms (paperwork) collected, and suggestions for eliminating unused or unnecessary data collection and streamlining the remaining data collection. Thirdly, the state agency hosted a meeting with the state staff, researchers and staff from all programs and agencies with state-funded contracts and took action. Paperwork reductions over the course of a 6-month outpatient treatment episode were estimated at 4 – 6 hours, with most of the time burden being eliminated from the intake process. PMID:19150201

  11. FORTRAN program for calculating velocities and streamlines on the hub-shroud mid-channel flow surface of an axial- or mixed-flow turbomachine. 1: User's manual

    NASA Technical Reports Server (NTRS)

    Katsanis, T.

    1973-01-01

    A FORTRAN 4 computer program has been developed that obtains a subsonic or shock-free transonic flow solution on the hub-shroud mid-channel flow surface of a turbomachine. The blade row may be fixed or rotating, and may be twisted and leaned. Flow may be axial or mixed, up to 45 deg from axial. Upstream and downstream flow variables may vary from hub to shroud, and provision is made to correct for loss of stagnation pressure. The results include velocities, streamlines, and flow angles on the flow surface; and approximate blade surface velocities. Subsonic solutions are obtained by a finite-difference stream-function solution. Transonic solutions are obtained by a velocity-gradient method, using information from a finite-difference stream-function solution at a reduced mass flow.

  12. Clawed forelimbs allow northern seals to eat like their ancient ancestors

    NASA Astrophysics Data System (ADS)

    Hocking, David P.; Marx, Felix G.; Sattler, Renae; Harris, Robert N.; Pollock, Tahlia I.; Sorrell, Karina J.; Fitzgerald, Erich M. G.; McCurry, Matthew R.; Evans, Alistair R.

    2018-04-01

    Streamlined flippers are often considered the defining feature of seals and sea lions, whose very name `pinniped' comes from the Latin pinna and pedis, meaning `fin-footed'. Yet not all pinniped limbs are alike. Whereas otariids (fur seals and sea lions) possess stiff streamlined forelimb flippers, phocine seals (northern true seals) have retained a webbed yet mobile paw bearing sharp claws. Here, we show that captive and wild phocines routinely use these claws to secure prey during processing, enabling seals to tear large fish by stretching them between their teeth and forelimbs. `Hold and tear' processing relies on the primitive forelimb anatomy displayed by phocines, which is also found in the early fossil pinniped Enaliarctos. Phocine forelimb anatomy and behaviour therefore provide a glimpse into how the earliest seals likely fed, and indicate what behaviours may have assisted pinnipeds along their journey from terrestrial to aquatic feeding.

  13. Visualizing Time-Varying Phenomena In Numerical Simulations Of Unsteady Flows

    NASA Technical Reports Server (NTRS)

    Lane, David A.

    1996-01-01

    Streamlines, contour lines, vector plots, and volume slices (cutting planes) are commonly used for flow visualization. These techniques are sometimes referred to as instantaneous flow visualization techniques because calculations are based on an instant of the flowfield in time. Although instantaneous flow visualization techniques are effective for depicting phenomena in steady flows,they sometimes do not adequately depict time-varying phenomena in unsteady flows. Streaklines and timelines are effective visualization techniques for depicting vortex shedding, vortex breakdown, and shock waves in unsteady flows. These techniques are examples of time-dependent flow visualization techniques, which are based on many instants of the flowfields in time. This paper describes the algorithms for computing streaklines and timelines. Using numerically simulated unsteady flows, streaklines and timelines are compared with streamlines, contour lines, and vector plots. It is shown that streaklines and timelines reveal vortex shedding and vortex breakdown more clearly than instantaneous flow visualization techniques.

  14. State Models to Incentivize and Streamline Small Hydropower Development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Curtis, Taylor; Levine, Aaron; Johnson, Kurt

    In 2016, the hydropower fleet in the United States produced more than 6 percent (approximately 265,829 gigawatt-hours [GWh]) of the total net electricity generation. The median-size hydroelectric facility in the United States is 1.6 MW and 75 percent of total facilities have a nameplate capacity of 10 MW or less. Moreover, the U.S. Department of Energy's Hydropower Vision study identified approximately 79 GW hydroelectric potential beyond what is already developed. Much of the potential identified is at low-impact new stream-reaches, existing conduits, and non-powered dams with a median project size of 10 MW or less. To optimize the potential andmore » value of small hydropower development, state governments are crafting policies that provide financial assistance and expedite state and federal review processes for small hydroelectric projects. This report analyzes state-led initiatives and programs that incentivize and streamline small hydroelectric development.« less

  15. Sensitivity analysis to aid shelter management decisions: how does altering expenditure affect operational viability?

    PubMed

    Widmar, Nicole Olynk; Lord, Emily; Litster, Annette

    2015-01-01

    Streamlining purchasing in nonhuman animal shelters can provide multiple financial benefits. Streamlining shelter inputs and thus reducing shelter costs can include trading paid labor and management for fewer, more involved volunteers or purchasing large quantities of medical supplies from fewer vendors to take advantage of bulk-purchasing discounts. Beyond direct savings, time and energy spent on purchasing and inventory control can be reduced through careful management. Although cost-cutting measures may seem attractive, shelter managers are cautioned to consider the potential unintended consequences of short-term cost reduction measures that could limit revenues or increase costs in the future. This analysis illustrates an example of the impact of cost reductions in specific expense categories and the impact on shelter net revenue, as well as the share of expenses across categories. An in-depth discussion of labor and purchasing cost-reducing strategies in the real world of animal shelter management is provided.

  16. FORTRAN program for calculating velocities and streamlines on the hub-shroud mid-channel flow surface of an axial-or mixed-flow turbomachine. 2: Programmer's manual

    NASA Technical Reports Server (NTRS)

    Katsanis, T.; Mcnally, W. D.

    1974-01-01

    A FORTRAN-IV computer program, MERIDL, has been developed that obtains a subsonic or shock-free transonic flow solution on the hub-shroud mid-channel flow surface of a turbomachine. The blade row may be fixed or rotating and may be twisted and leaned. Flow may be axial or mixed, up to 45 deg from axial. Upstream and downstream flow variables can vary from hub to shroud, and provision is made to correct for loss of stagnation pressure. The results include velocities, streamlines, and flow angles on the flow surface and approximate blade surface velocities. Subsonic solutions are obtained by a finite-difference stream-function solution. Transonic solutions are obtained by a velocity-gradient method, using information from a finite-difference stream-function solution at a reduced mass flow.

  17. 10th European Zebrafish Meeting 2017, Budapest: Husbandry Workshop Summary.

    PubMed

    Oltová, Jana; Barton, Carrie; Certal, Ana Catarina; Argenton, Francesco; Varga, Zoltán M

    2018-01-02

    A husbandry workshop on July 3, 2017, at the 10th European Zebrafish Meeting in Budapest, Hungary (July 3-July 7, 2017), focused on the standardization, optimization, and streamlining of fish facility procedures. Standardization can be achieved for example by developing novel software and hardware tools, such as a fish facility database for husbandry and environmental facility management (Zebrabase, Oltova), or a hand-held, air-pressurized fish feeder for consistent food distribution (Blowfish, Argenton). Streamlining is achieved when work hours are reduced, as with the standardized fish feeder, or by limiting the number and types of fish diets and observing the effect on animal welfare and performance (Barton). Testing the characteristics of new fish diets and observing whether they produce better experimental outcomes (Certal) optimizes diets and improves fish productivity. Collectively, the workshop presentations emphasized how consistency and harmonization of husbandry procedures within and across aquatic facilities yield reproducible scientific outcomes.

  18. Validation of DTI Tractography-Based Measures of Primary Motor Area Connectivity in the Squirrel Monkey Brain

    PubMed Central

    Gao, Yurui; Choe, Ann S.; Stepniewska, Iwona; Li, Xia; Avison, Malcolm J.; Anderson, Adam W.

    2013-01-01

    Diffusion tensor imaging (DTI) tractography provides noninvasive measures of structural cortico-cortical connectivity of the brain. However, the agreement between DTI-tractography-based measures and histological ‘ground truth’ has not been quantified. In this study, we reconstructed the 3D density distribution maps (DDM) of fibers labeled with an anatomical tracer, biotinylated dextran amine (BDA), as well as DTI tractography-derived streamlines connecting the primary motor (M1) cortex to other cortical regions in the squirrel monkey brain. We evaluated the agreement in M1-cortical connectivity between the fibers labeled in the brain tissue and DTI streamlines on a regional and voxel-by-voxel basis. We found that DTI tractography is capable of providing inter-regional connectivity comparable to the neuroanatomical connectivity, but is less reliable measuring voxel-to-voxel variations within regions. PMID:24098365

  19. Ultralow percolation threshold of single walled carbon nanotube-epoxy composites synthesized via an ionic liquid dispersant/initiator

    NASA Astrophysics Data System (ADS)

    Watters, Arianna L.; Palmese, Giuseppe R.

    2014-09-01

    Uniform dispersion of single walled carbon nanotubes (SWNTs) in an epoxy was achieved by a streamlined mechano-chemical processing method. SWNT-epoxy composites were synthesized using a room temperature ionic liquid (IL) with an imidazolium cation and dicyanamide anion. The novel approach of using ionic liquid that behaves as a dispersant for SWNTs and initiator for epoxy polymerization greatly simplifies nanocomposite synthesis. The material was processed using simple and scalable three roll milling. The SWNT dispersion of the resultant composite was evaluated by electron microscopy and electrical conductivity measurements in conjunction with percolation theory. Processing conditions were optimized to achieve the lowest possible percolation threshold, 4.29 × 10-5 volume fraction SWNTs. This percolation threshold is among the best reported in literature yet it was obtained using a streamlined method that greatly simplifies processing.

  20. Nonequilibrium recombination after a curved shock wave

    NASA Astrophysics Data System (ADS)

    Wen, Chihyung; Hornung, Hans

    2010-02-01

    The effect of nonequilibrium recombination after a curved two-dimensional shock wave in a hypervelocity dissociating flow of an inviscid Lighthill-Freeman gas is considered. An analytical solution is obtained with the effective shock values derived by Hornung (1976) [5] and the assumption that the flow is ‘quasi-frozen’ after a thin dissociating layer near the shock. The solution gives the expression of dissociation fraction as a function of temperature on a streamline. A rule of thumb can then be provided to check the validity of binary scaling for experimental conditions and a tool to determine the limiting streamline that delineates the validity zone of binary scaling. The effects on the nonequilibrium chemical reaction of the large difference in free stream temperature between free-piston shock tunnel and equivalent flight conditions are discussed. Numerical examples are presented and the results are compared with solutions obtained with two-dimensional Euler equations using the code of Candler (1988) [10].

  1. Streamlining Software Aspects of Certification: Technical Team Report on the First Industry Workshop

    NASA Technical Reports Server (NTRS)

    Hayhurst, Kelly J.; Holloway, C. Michael; Knight, John C.; Leveson, Nancy G.; Yang, Jeffrey C.; Dorsey, Cheryl A.; McCormick, G. Frank

    1998-01-01

    To address concerns about time and expense associated with software aspects of certification, the Federal Aviation Administration (FAA) began the Streamlining Software Aspects of Certification (SSAC) program. As part of this program, a Technical Team was established to determine whether the cost and time associated with certifying aircraft can be reduced while maintaining or improving safety, with the intent of impacting the FAA's Flight 2000 program. The Technical Team conducted a workshop to gain a better understanding of the major concerns in industry about software cost and schedule. Over 120 people attended the workshop, including representatives from the FAA,commercial transport and general aviation aircraft manufacturers and suppliers, and procurers and developers of non-airborne systems; and, more than 200 issues about software aspects of certification were recorded. This paper provides an overview of the SSAC program, motivation for the workshop, details of the workshop activities and outcomes, and recommendations for follow-on work.

  2. Evaluation of Therapeutics for Advanced-Stage Heart Failure and Other Severely-Debilitating or Life-Threatening Diseases.

    PubMed

    Prescott, J S; Andrews, P A; Baker, R W; Bogdanffy, M S; Fields, F O; Keller, D A; Lapadula, D M; Mahoney, N M; Paul, D E; Platz, S J; Reese, D M; Stoch, S A; DeGeorge, J J

    2017-08-01

    Severely-debilitating or life-threatening (SDLT) diseases include conditions in which life expectancy is short or quality of life is greatly diminished despite available therapies. As such, the medical context for SDLT diseases is comparable to advanced cancer and the benefit vs. risk assessment and development of SDLT disease therapeutics should be similar to that of advanced cancer therapeutics. A streamlined development approach would allow patients with SDLT conditions earlier access to therapeutics and increase the speed of progression through development. In addition, this will likely increase the SDLT disease therapeutic pipeline, directly benefiting patients and reducing the economic and societal burden of SDLT conditions. Using advanced-stage heart failure (HF) as an example that illustrates the concepts applicable to other SDLT indications, this article proposes a streamlined development paradigm for SDLT disease therapeutics and recommends development of aligned global regulatory guidance. © 2017 American Society for Clinical Pharmacology and Therapeutics.

  3. Clawed forelimbs allow northern seals to eat like their ancient ancestors

    PubMed Central

    Sattler, Renae; Harris, Robert N.; Pollock, Tahlia I.; Sorrell, Karina J.; Fitzgerald, Erich M. G.; McCurry, Matthew R.

    2018-01-01

    Streamlined flippers are often considered the defining feature of seals and sea lions, whose very name ‘pinniped’ comes from the Latin pinna and pedis, meaning ‘fin-footed’. Yet not all pinniped limbs are alike. Whereas otariids (fur seals and sea lions) possess stiff streamlined forelimb flippers, phocine seals (northern true seals) have retained a webbed yet mobile paw bearing sharp claws. Here, we show that captive and wild phocines routinely use these claws to secure prey during processing, enabling seals to tear large fish by stretching them between their teeth and forelimbs. ‘Hold and tear’ processing relies on the primitive forelimb anatomy displayed by phocines, which is also found in the early fossil pinniped Enaliarctos. Phocine forelimb anatomy and behaviour therefore provide a glimpse into how the earliest seals likely fed, and indicate what behaviours may have assisted pinnipeds along their journey from terrestrial to aquatic feeding. PMID:29765684

  4. Enhancer scanning to locate regulatory regions in genomic loci

    PubMed Central

    Buckley, Melissa; Gjyshi, Anxhela; Mendoza-Fandiño, Gustavo; Baskin, Rebekah; Carvalho, Renato S.; Carvalho, Marcelo A.; Woods, Nicholas T.; Monteiro, Alvaro N.A.

    2016-01-01

    The present protocol provides a rapid, streamlined and scalable strategy to systematically scan genomic regions for the presence of transcriptional regulatory regions active in a specific cell type. It creates genomic tiles spanning a region of interest that are subsequently cloned by recombination into a luciferase reporter vector containing the Simian Virus 40 promoter. Tiling clones are transfected into specific cell types to test for the presence of transcriptional regulatory regions. The protocol includes testing of different SNP (single nucleotide polymorphism) alleles to determine their effect on regulatory activity. This procedure provides a systematic framework to identify candidate functional SNPs within a locus during functional analysis of genome-wide association studies. This protocol adapts and combines previous well-established molecular biology methods to provide a streamlined strategy, based on automated primer design and recombinational cloning to rapidly go from a genomic locus to a set of candidate functional SNPs in eight weeks. PMID:26658467

  5. Clawed forelimbs allow northern seals to eat like their ancient ancestors.

    PubMed

    Hocking, David P; Marx, Felix G; Sattler, Renae; Harris, Robert N; Pollock, Tahlia I; Sorrell, Karina J; Fitzgerald, Erich M G; McCurry, Matthew R; Evans, Alistair R

    2018-04-01

    Streamlined flippers are often considered the defining feature of seals and sea lions, whose very name 'pinniped' comes from the Latin pinna and pedis , meaning 'fin-footed'. Yet not all pinniped limbs are alike. Whereas otariids (fur seals and sea lions) possess stiff streamlined forelimb flippers, phocine seals (northern true seals) have retained a webbed yet mobile paw bearing sharp claws. Here, we show that captive and wild phocines routinely use these claws to secure prey during processing, enabling seals to tear large fish by stretching them between their teeth and forelimbs. 'Hold and tear' processing relies on the primitive forelimb anatomy displayed by phocines, which is also found in the early fossil pinniped Enaliarctos . Phocine forelimb anatomy and behaviour therefore provide a glimpse into how the earliest seals likely fed, and indicate what behaviours may have assisted pinnipeds along their journey from terrestrial to aquatic feeding.

  6. Streakline flow visualization study of a horseshoe vortex in a large-scale, two-dimensional turbine stator cascade

    NASA Technical Reports Server (NTRS)

    Gaugler, R. E.; Russell, L. M.

    1979-01-01

    Neutrally bouyant helium-filled bubbles were observed as they followed the streamlines in a horseshoe vortex system around the vane leading edge in a large scale, two dimensional, turbine stator cascade. Inlet Reynolds number, based on true chord, ranged between 100,000 to 300,000. Bubbles were introduced into the endwall boundary layer through a slot upstream of the vane leading edge. The paths of the bubbles were recorded photographically as streaklines on 16 mm movie film. Individual frames from the film were selected, and overlayed to show the details of the horseshoe vortex around the leading edge. The transport of the vortex across the passage near the leading edge is clearly seen when compared to the streaks formed by bubbles carried in the main stream. Limiting streamlines on the endwall surface were traced by the flow of oil drops.

  7. Aerodynamic Characteristics of a Refined Deep-step Planing-tail Flying-boat Hull with Various Forebody and Afterbody Shapes

    NASA Technical Reports Server (NTRS)

    Riebe, John M; Naeseth, Rodger L

    1952-01-01

    An investigation was made in the Langley 300-mph 7- by 10-foot tunnel to determine the aerodynamic characteristics of a refined deep-step planing-tail hull with various forebody and afterbody shapes and, for comparison, a streamline body simulating the fuselage of a modern transport airplane. The results of the tests indicated that the configurations incorporating a forebody with a length-beam ratio of 7 had lower minimum drag coefficients than the configurations incorporating a forebody with length-beam ratio of 5. The lowest minimum drag coefficients, which were considerably less than that of a conventional hull and slightly less than that of a streamline body, were obtained on the length-beam-ratio-7 forebody, alone and with round center boom. Drag coefficients and longitudinal- and lateral-stability parameters presented include the interference of a 21-percent-thick support wing.

  8. Off-Design Performance of a Streamline-Traced, External-Compression Supersonic Inlet

    NASA Technical Reports Server (NTRS)

    Slater, John W.

    2017-01-01

    A computational study was performed to explore the aerodynamic performance of a streamline-traced, external-compression inlet designed for Mach 1.664 at off-design conditions of freestream Mach number, angle-of-attack, and angle-of-sideslip. Serious degradation of the inlet performance occurred for negative angles-of-attack and angles-of-sideslip greater than 3 degrees. At low subsonic speeds, the swept leading edges of the inlet created a pair of vortices that propagated to the engine face. Increasing the bluntness of the cowl lip showed no real improvement in the inlet performance at the low speeds, but did improve the inlet performance at the design conditions. Reducing the inlet flow rate improved the inlet performance, but at the likely expense of reduced thrust of the propulsion system. Deforming the cowl lip for low-speed operation of the inlet increased the inlet capture area and improved the inlet performance.

  9. Universal immunogenicity validation and assessment during early biotherapeutic development to support a green laboratory.

    PubMed

    Bautista, Ami C; Zhou, Lei; Jawa, Vibha

    2013-10-01

    Immunogenicity support during nonclinical biotherapeutic development can be resource intensive if supported by conventional methodologies. A universal indirect species-specific immunoassay can eliminate the need for biotherapeutic-specific anti-drug antibody immunoassays without compromising quality. By implementing the R's of sustainability (reduce, reuse, rethink), conservation of resources and greener laboratory practices were achieved in this study. Statistical analysis across four biotherapeutics supported identification of consistent product performance standards (cut points, sensitivity and reference limits) and a streamlined universal anti-drug antibody immunoassay method implementation strategy. We propose an efficient, fit-for-purpose, scientifically and statistically supported nonclinical immunogenicity assessment strategy. Utilization of a universal method and streamlined validation, while retaining comparability to conventional immunoassays and meeting the industry recommended standards, provides environmental credits in the scientific laboratory. Collectively, individual reductions in critical material consumption, energy usage, waste and non-environment friendly consumables, such as plastic and paper, support a greener laboratory environment.

  10. Streamlining the use of BOLD specimen data to record species distributions: a case study with ten Nearctic species of Microgastrinae (Hymenoptera: Braconidae)

    PubMed Central

    Penev, Lyubomir; Ratnasingham, Sujeevan; Smith, M. Alex; Sones, Jayme; Telfer, Angela; deWaard, Jeremy R.; Hebert, Paul D. N.

    2014-01-01

    Abstract The Barcode of Life Data Systems (BOLD) is designed to support the generation and application of DNA barcode data, but it also provides a unique source of data with potential for many research uses. This paper explores the streamlining of BOLD specimen data to record species distributions – and its fast publication using the Biodiversity Data Journal (BDJ), and its authoring platform, the Pensoft Writing Tool (PWT). We selected a sample of 630 specimens and 10 species of a highly diverse group of parasitoid wasps (Hymenoptera: Braconidae, Microgastrinae) from the Nearctic region and used the information in BOLD to uncover a significant number of new records (of locality, provinces, territories and states). By converting specimen information (such as locality, collection date, collector, voucher depository) from the BOLD platform to the Excel template provided by the PWT, it is possible to quickly upload and generate long lists of "Material Examined" for papers discussing taxonomy, ecology and/or new distribution records of species. For the vast majority of publications including DNA barcodes, the generation and publication of ancillary data associated with the barcoded material is seldom highlighted and often disregarded, and the analysis of those data sets to uncover new distribution patterns of species has rarely been explored, even though many BOLD records represent new and/or significant discoveries. The introduction of journals specializing in – and streamlining – the release of these datasets, such as the BDJ, should facilitate thorough analysis of these records, as shown in this paper. PMID:25473326

  11. Influence of strut cross-section of stents on local hemodynamics in stented arteries

    NASA Astrophysics Data System (ADS)

    Jiang, Yongfei; Zhang, Jun; Zhao, Wanhua

    2016-05-01

    Stenting is a very effective treatment for stenotic vascular diseases, but vascular geometries altered by stent implantation may lead to flow disturbances which play an important role in the initiation and progression of restenosis, especially in the near wall in stented arterial regions. So stent designs have become one of the indispensable factors needed to be considered for reducing the flow disturbances. In this paper, the structural designs of strut cross-section are considered as an aspect of stent designs to be studied in details. Six virtual stents with different strut cross-section are designed for deployments in the same ideal arterial model. Computational fluid dynamics (CFD) methods are performed to study how the shape and the aspect ratio (AR) of strut cross-section modified the local hemodynamics in the stented segments. The results indicate that stents with different strut cross-sections have different influence on the hemodynamics. Stents with streamlined cross-sectional struts for circular arc or elliptical arc can significantly enhance wall shear stress (WSS) in the stented segments, and reduce the flow disturbances around stent struts. The performances of stents with streamlined cross-sectional struts are better than that of stents with non-streamlined cross-sectional struts for rectangle. The results also show that stents with a larger AR cross-section are more conductive to improve the blood flow. The present study provides an understanding of the flow physics in the vicinity of stent struts and indicates that the shape and AR of strut cross-section ought to be considered as important factors to minimize flow disturbance in stent designs.

  12. Flow and transport in digitized images of Berea sandstone: ergodicity, stationarity and upscaling

    NASA Astrophysics Data System (ADS)

    Puyguiraud, A.; Dentz, M.; Gouze, P.

    2017-12-01

    We perform Stokes flow simulations on digitized images of a Berea sandstone sample obtained through micro-tomography imaging and segmentation processes. We obtain accurate information on the transport using a streamline reconstruction algorithm which uses the velocity field obtained from the flow simulation as input data. This technique is based on the method proposed by Pollock (Groundwater, 1988) but employs a quadratic interpolation near the rock mesh cells of the domain similarly to Mostaghimi et al. (SPE, 2012). This allows an accurate resolution of the velocity field near the solid interface which plays an important role on the transport characteristics, such as the probability density of first arrival times and the growth of the mean squared displacement, among others, which exhibit non-Fickian behavior. We analyze Lagrangian and Eulerian velocity statistics and their relation, and then focus on the ergodicity and the stationarity properties of the transport.We analyze the temporal evolution of Lagrangian velocity statistics for different injection conditions, and findd quick convergence to a limiting velocity distribution, indicating the transport to be near-stationary. The equivalence between velocity samplings within and across streamlines, as well as the independency of the statistics on the number of sampled streamlines, lead as to conclude that the transport may be modeled as ergodic.These characteristics then allow us to upscale the 3-dimensional simulations using a 1-dimensional Continuous Time Random Walk model. This model, parametrized by the velocity results and the characteristic correlation length obtained from the above mentioned simulations, is able to efficiently reproduce the results and to predict larger scale behaviors.

  13. A streamlined failure mode and effects analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ford, Eric C., E-mail: eford@uw.edu; Smith, Koren; Terezakis, Stephanie

    Purpose: Explore the feasibility and impact of a streamlined failure mode and effects analysis (FMEA) using a structured process that is designed to minimize staff effort. Methods: FMEA for the external beam process was conducted at an affiliate radiation oncology center that treats approximately 60 patients per day. A structured FMEA process was developed which included clearly defined roles and goals for each phase. A core group of seven people was identified and a facilitator was chosen to lead the effort. Failure modes were identified and scored according to the FMEA formalism. A risk priority number,RPN, was calculated and usedmore » to rank failure modes. Failure modes with RPN > 150 received safety improvement interventions. Staff effort was carefully tracked throughout the project. Results: Fifty-two failure modes were identified, 22 collected during meetings, and 30 from take-home worksheets. The four top-ranked failure modes were: delay in film check, missing pacemaker protocol/consent, critical structures not contoured, and pregnant patient simulated without the team's knowledge of the pregnancy. These four failure modes hadRPN > 150 and received safety interventions. The FMEA was completed in one month in four 1-h meetings. A total of 55 staff hours were required and, additionally, 20 h by the facilitator. Conclusions: Streamlined FMEA provides a means of accomplishing a relatively large-scale analysis with modest effort. One potential value of FMEA is that it potentially provides a means of measuring the impact of quality improvement efforts through a reduction in risk scores. Future study of this possibility is needed.« less

  14. Smart management of sample dilution using an artificial neural network to achieve streamlined processes and saving resources: the automated nephelometric testing of serum free light chain as case study.

    PubMed

    Ialongo, Cristiano; Pieri, Massimo; Bernardini, Sergio

    2017-02-01

    Saving resources is a paramount issue for the modern laboratory, and new trainable as well as smart technologies can be used to allow the automated instrumentation to manage samples more efficiently in order to achieve streamlined processes. In this regard the serum free light chain (sFLC) testing represents an interesting challenge, as it usually causes using a number of assays before achieving an acceptable result within the analytical range. An artificial neural network based on the multi-layer perceptron (MLP-ANN) was used to infer the starting dilution status of sFLC samples based on the information available through the laboratory information system (LIS). After the learning phase, the MLP-ANN simulation was applied to the nephelometric testing routinely performed in our laboratory on a BN ProSpec® System analyzer (Siemens Helathcare) using the N Latex FLC kit. The MLP-ANN reduced the serum kappa free light chain (κ-FLC) and serum lambda free light chain (λ-FLC) wasted tests by 69.4% and 70.8% with respect to the naïve stepwise dilution scheme used by the automated analyzer, and by 64.9% and 66.9% compared to a "rational" dilution scheme based on a 4-step dilution. Although it was restricted to follow-up samples, the MLP-ANN showed good predictive performance, which alongside the possibility to implement it in any automated system, made it a suitable solution for achieving streamlined laboratory processes and saving resources.

  15. A Recipe for Streamlining Mission Management

    NASA Technical Reports Server (NTRS)

    Mitchell, Andrew E.; Semancik, Susan K.

    2004-01-01

    This paper describes a project's design and implementation for streamlining mission management with knowledge capture processes across multiple organizations of a NASA directorate. Thc project's focus is on standardizing processes and reports; enabling secure information access and case of maintenance; automating and tracking appropriate workflow rules through process mapping; and infusing new technologies. This paper will describe a small team's experiences using XML technologies through an enhanced vendor suite of applications integrated on Windows-based platforms called the Wallops Integrated Scheduling and Document Management System (WISDMS). This paper describes our results using this system in a variety of endeavors, including providing range project scheduling and resource management for a Range and Mission Management Office; implementing an automated Customer Feedback system for a directorate; streamlining mission status reporting across a directorate; and initiating a document management, configuration management and portal access system for a Range Safety Office's programs. The end result is a reduction of the knowledge gap through better integration and distribution of information, improved process performance, automated metric gathering, and quicker identification of problem areas and issues. However, the real proof of the pudding comes through overcoming the user's reluctance to replace familiar, seasoned processes with new technology ingredients blended with automated procedures in an untested recipe. This paper shares some of the team's observations that led to better implementation techniques, as well as an IS0 9001 Best Practices citation. This project has provided a unique opportunity to advance NASA's competency in new technologies, as well as to strategically implement them within an organizational structure, while wetting the appetite for continued improvements in mission management.

  16. Applying industrial process improvement techniques to increase efficiency in a surgical practice.

    PubMed

    Reznick, David; Niazov, Lora; Holizna, Eric; Siperstein, Allan

    2014-10-01

    The goal of this study was to examine how industrial process improvement techniques could help streamline the preoperative workup. Lean process improvement was used to streamline patient workup at an endocrine surgery service at a tertiary medical center utilizing multidisciplinary collaboration. The program consisted of several major changes in how patients are processed in the department. The goal was to shorten the wait time between initial call and consult visit and between consult and surgery. We enrolled 1,438 patients enrolled in the program. The wait time from the initial call until consult was reduced from 18.3 ± 0.7 to 15.4 ± 0.9 days. Wait time from consult until operation was reduced from 39.9 ± 1.5 to 33.9 ± 1.3 days for the overall practice and to 15.0 ± 4.8 days for low-risk patients. Patient cancellations were reduced from 27.9 ± 2.4% to 17.3 ± 2.5%. Overall patient flow increased from 30.9 ± 5.1 to 52.4 ± 5.8 consults per month (all P < .01). Utilizing process improvement methodology, surgery patients can benefit from an improved, streamlined process with significant reduction in wait time from call to initial consult and initial consult to surgery, with reduced cancellations. This generalized process has resulted in increased practice throughput and efficiency and is applicable to any surgery practice. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. PRN 2001-2: Acute Toxicity Data Requirements For Granular Pesticide Products, Including Those With Granular Fertilizers in the Product.

    EPA Pesticide Factsheets

    This PR Notice announces guidance intended to streamline the acute toxicity review and classification process for certain granular pesticide products, including those products that contain granular fertilizers.

  18. Tennessee long-range transportation plan : aviation system plan update

    DOT National Transportation Integrated Search

    2005-01-01

    This plan update is streamlined in nature and will only consider the ttates six commercial service airports and 14 regional airports. The tasks completed for this update included an inventory of facilities, aviation industry review, review and upd...

  19. Building contacts for the SKA

    NASA Astrophysics Data System (ADS)

    Bowler, Sue

    2016-06-01

    The Square Kilometre Array needs industrial expertise; SKA technology will, in turn, streamline big-data challenges for business and society. Or that's the idea: Sue Bowler reports on a day of networking designed to build industry-academia collaborations in the UK.

  20. Elevating the role of finance at Mary Lanning Healthcare.

    PubMed

    Hoffman, Amanda; Spence, Jay

    2013-11-01

    To effectively partner with hospital operations leaders, healthcare finance leaders should: Streamline and align financial planning and budgeting functions across the organization; Ensure capital planning is regarded as a strategic process; Optimize performance monitoring across management levels.

  1. Streamlining Energy Efficiency for Schools Act of 2013

    THOMAS, 113th Congress

    Sen. Udall, Mark [D-CO

    2013-06-03

    Senate - 06/25/2013 Committee on Energy and Natural Resources Subcommittee on Energy. Hearings held. With printed Hearing: S.Hrg. 113-70. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  2. Streamlining Energy Efficiency for Schools Act of 2014

    THOMAS, 113th Congress

    Rep. Cartwright, Matt [D-PA-17

    2014-02-26

    Senate - 06/24/2014 Received in the Senate and Read twice and referred to the Committee on Energy and Natural Resources. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  3. 77 FR 12528 - Amendments to Commission's Rules of Practice and Procedure-Subparts E and L

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-01

    ..., he advocates the use of a cloud computing system in which documents can be filed giving multiple... concerns. Barillo believes that cloud computing would streamline efficiency and reduce staff labor in...

  4. Project consistency with transportation plans and air quality conformity workshops : technical report.

    DOT National Transportation Integrated Search

    2015-04-01

    This implementation project supports streamlined project delivery, one of the goals outlined by the Texas : Department of Transportation (TxDOT) leadership to achieve an efficient and effective transportation system : in Texas. The project benefits T...

  5. c-Mantic: A Cytoscape plugin for Semantic Web

    EPA Science Inventory

    Semantic Web tools can streamline the process of storing, analyzing and sharing biological information. Visualization is important for communicating such complex biological relationships. Here we use the flexibility and speed of the Cytoscape platform to interactively visualize s...

  6. The Storyboard's Big Picture

    NASA Technical Reports Server (NTRS)

    Malloy, Cheryl A.; Cooley, William

    2003-01-01

    At Science Applications International Corporation (SAIC), Cape Canaveral Office, we're using a project management tool that facilitates team communication, keeps our project team focused, streamlines work and identifies potential issues. What did it cost us to install the tool? Almost nothing.

  7. Demystifying the peer-review process - workshop

    EPA Science Inventory

    Scientific writing and peer-review are integral parts of the publishing process. This workshop aims to demystify the peer-review process for early career scientists and provide insightful tips for streamlining the submission and peer review process for all researchers. Providing ...

  8. Final report on the maintenance asset management project : phase II.

    DOT National Transportation Integrated Search

    2013-07-01

    Iowa Department of Transportation (IA DOT) is finalizing research to streamline field inventory/inspection of culverts by Maintenance and Construction staff while maximizing the use of tablet technologies. The project began in 2011 to develop some ne...

  9. Task Decomposition Model for Dispatchers in Dynamic Scheduling of Demand Responsive Transit Systems

    DOT National Transportation Integrated Search

    2000-06-01

    Since the passage of ADA, the demand for paratransit service is steadily increasing. Paratransit companies are relying on computer automation to streamline dispatch operations, increase productivity and reduce operator stress and error. Little resear...

  10. NREL Helps Streamline Solar Power Installations for Local Governments |

    Science.gov Websites

    derived from examples set by model cities, such as Austin and San Francisco. Certain prerequisites mandate serves to push communities forward that want a higher designation. One city interested in the addition of

  11. Opening Up New Possibilities.

    ERIC Educational Resources Information Center

    Kennedy, Mike

    2001-01-01

    Discusses technology's impact on educational facilities and operations. Technology's influence on a school's ability to streamline their business operations and manage their facilities more efficiency is examined, and how Baylor University (Waco, TX) used technology to cut energy costs is highlighted. (GR)

  12. 33 CFR 148.209 - How is the application processed?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... application and the Maritime Administration publishes the notice of application under 33 U.S.C. 1504(c) in the... hyperlink: http://www.uscg.mil/hq/G-M/mso/docs/dwp_ white_house_task_force_energy_ streamlining.pdf. (b...

  13. 33 CFR 148.209 - How is the application processed?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... application and the Maritime Administration publishes the notice of application under 33 U.S.C. 1504(c) in the... hyperlink: http://www.uscg.mil/hq/G-M/mso/docs/dwp_ white_house_task_force_energy_ streamlining.pdf. (b...

  14. Connected commercial vehicles-integrated truck project : vehicle build test report.

    DOT National Transportation Integrated Search

    2000-12-01

    This paper examines the ways ITS is changing the way federal and state motor carrier agencies conduct business with the motor carrier industry. New technologies are streamlining credentialing operations, reducing delays for safe carriers, and improvi...

  15. 78 FR 42921 - Amendments to Regulations Governing Ocean Transportation Intermediary Licensing and Financial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-18

    ... Regulations Governing Ocean Transportation Intermediary Licensing and Financial Responsibility Requirements... the licensing, financial responsibility requirements and duties of Ocean Transportation Intermediaries... effectiveness, improve transparency, streamline processes and reduce regulatory burdens. The Commission received...

  16. Cloud-Aerosol Transport System (CATS)

    Atmospheric Science Data Center

    2017-04-18

    ... build-to-cost project development with streamlined management structure.  Conducted successful underflights of opportunity ... (CPL) on the ER-2 on Feb 10, 17, 20 and 21. For more information, please see the CATS homepage  or the attached  presentation ...

  17. Are You Neutral About Net Neutrality

    DTIC Science & Technology

    2007-06-20

    Alaska War on Terrorism Universal Service Reform Streamlining Franchising Process Video Content Municipal Broadband Wireless Innovation Networks Digital...Chair, Joe Barton (R), Texas National Video Franchising Network Neutrality/Enforcement of Broadband Policy VoIP/E9ll Municipal Provision of Services

  18. SeqAPASS (Sequence Alignment to Predict Across Species Susceptibility) software and documentation

    EPA Science Inventory

    SeqAPASS is a software application facilitates rapid and streamlined, yet transparent, comparisons of the similarity of toxicologically-significant molecular targets across species. The present application facilitates analysis of primary amino acid sequence similarity (including ...

  19. Streamlining ITS planning : identifying common ITS needs : national ITS architecture

    DOT National Transportation Integrated Search

    1999-01-01

    This brochure gives an overview of the National Intelligent Transportation Systems (ITS) Architecture. The objects of the program include: to aid in the purchase of compatible equipment and services; to guide multilevel efforts in implementing compat...

  20. Project inspection using mobile technology - phase II : assessing the impacts of mobile technology on project inspection.

    DOT National Transportation Integrated Search

    2015-01-01

    As mobile technology becomes widely available and affordable, transportation agencies can use this : technology to streamline operations involved within project inspection. This research, conducted in two : phases, identified opportunities for proces...

  1. Final Rule for Procedures for Testing Highway and Nonroad Engines and Omnibus Technical Amendments

    EPA Pesticide Factsheets

    This common set of test requirements is intended to streamline laboratory efforts for EPA and industry and to form the basis for internationally harmonized test procedures for nearly all categories of engines.

  2. White Sands Missile Range Non-Track Optics: Streamlining the Process of Conducting Business for Improved Customer Support

    DTIC Science & Technology

    2013-12-01

    45 A. METHODOLOGY... 45 B. ANALYSIS .....................................................................................................46 C...digital airborne guidance section MFOM MLRS family of munitions MLRS Multiple Launch Rocket System MMW millimeter wave MT material test MTM

  3. Lean coding machine. Facilities target productivity and job satisfaction with coding automation.

    PubMed

    Rollins, Genna

    2010-07-01

    Facilities are turning to coding automation to help manage the volume of electronic documentation, streamlining workflow, boosting productivity, and increasing job satisfaction. As EHR adoption increases, computer-assisted coding may become a necessity, not an option.

  4. Katherine Young, P.E. | NREL

    Science.gov Websites

    ) Water rights and resources engineering Database planning and development Research Interests Collection lean principles to streamline exploration and drilling and reduce error/risk Research, development and Groundwater modeling Quantitative methods in water resource engineering Water resource engineering and

  5. Innovation in environmental streamlining and project delivery : the Oregon State Bridge Delivery Program.

    DOT National Transportation Integrated Search

    2007-01-01

    Surface transportation planning in the United States has become a complex system of intergovernmental planning : and environmental compliance requirements over the past several decades. As a result, the process from planning : stage to project implem...

  6. 78 FR 15615 - Reporting Requirements for U.S. Providers of International Telecommunications Services

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ...] Reporting Requirements for U.S. Providers of International Telecommunications Services AGENCY: Federal... (Commission) eliminates unnecessary information, streamlines the filing of annual international traffic and... the collection of data on international telecommunications services, the Commission consolidated the...

  7. A Framework for Fundamental Change in the Community College.

    ERIC Educational Resources Information Center

    Lorenzo, Albert L.; LeCroy, Nancy Armes

    1994-01-01

    Examines the underlying forces prompting fundamental change in community colleges to meet the requirements of the Information Age. Recommends that community colleges direct institutional energy toward thinking holistically, streamlining governance, redefining faculty roles, diversifying funding, increasing student options, assuring educational…

  8. The Learning Organization: Theory into Practice.

    ERIC Educational Resources Information Center

    Otala, Matti

    1995-01-01

    Key elements of learning organizations are as follows: understanding strengths, weaknesses, threats, and opportunities; open-book management; streamlined processes; team spirit; lifelong learning and skill recycling; and removing anxiety. A learning organization consists of empowered, motivated people committed to improving continuously. (SK)

  9. 76 FR 32866 - Cable Landing Licenses; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 1 [DA 11-668] Cable Landing Licenses; Correction... Systems Agency and affects applicants requesting streamlined processing of cable landing license... paragraph (j) to read as follows: Sec. 1.767 Cable landing licenses. * * * * * (j) Applications for...

  10. 75 FR 66709 - Commercial Radio Operators Rules

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-29

    .... SUMMARY: This document proposes to amend our rules concerning commercial radio operator licenses for... operators service, to determine which rules can be clarified, streamlined, or eliminated. DATES: Submit... Radiotelegraph Operator's Certificates, and seek comment on extending the current five-year license for...

  11. Implementation of gINT software at the Virginia Department of Transportation.

    DOT National Transportation Integrated Search

    2008-01-01

    A set of software tools was developed to enable staff of the Virginia Department of Transportation (VDOT) and consultants to streamline processing of subsurface exploration data. Built around the gINT program (geotechnical database and graphics packa...

  12. 77 FR 43773 - Wireline Competition Bureau Seeks Further Comment on Issues in the Rural Health Care Reform...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-26

    ... and Primary programs in supporting any recommendations for streamlined application procedures. b. Post... ineligible HCPs) by taking into account a variety of healthcare-specific factors. We note that in the Pilot...

  13. 2 CFR 225.15 - Background.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agreements OFFICE OF MANAGEMENT AND BUDGET CIRCULARS AND GUIDANCE Reserved COST PRINCIPLES FOR STATE, LOCAL... grant streamlining effort under Public Law 106-107, Federal Financial Award Management Improvement Act... review existing cost principles for Federal awards to State, local, and Indian tribal governments...

  14. 77 FR 10799 - Revised Guidance for Requesting One-Time Movement (OTM) Approvals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-23

    ... DEPARTMENT OF TRANSPORTATION Federal Railroad Administration Revised Guidance for Requesting One-Time Movement (OTM) Approvals AGENCY: Federal Railroad Administration (FRA), Department of... as one-time movement approvals (OTMA). Recently, FRA revised its OTMA procedures to streamline the...

  15. Building a Global Learning Organization: Lessons from the World's Top Corporations.

    ERIC Educational Resources Information Center

    Marquardt, Michael J.

    1995-01-01

    Research on 50 organizations elicited 19 attributes of learning organizations: individual learning, group learning, streamlined structure, corporate learning culture, empowerment, environmental scanning, knowledge creation/transfer, learning technology, quality, learning strategy, supportive atmosphere, teamwork/networking, vision, acculturation,…

  16. REVISED EMISSIONS ESTIMATION METHODOLOGIES FOR INDUSTRIAL, RESIDENTIAL, AND ELECTRIC UTILITY STATIONARY COMBUSTION SOURCES

    EPA Science Inventory

    The report describes the development of improved and streamlined EPA emission estimation methods for stationary combustion area sources by the Joint Emissions Inventory Oversight Group (JEIOG) research program. These sources include categories traditionally labeled "other statio...

  17. 75 FR 28517 - 2004 and 2006 Biennial Regulatory Reviews-Streamlining and Other Revisions of the Commission's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ... required if the structure exceeds 200 feet in height or if it requires aeronautical study, unless an... associated study, unless otherwise specified, rather than in any particular circular. The Commission seeks... [[Page 28519

  18. 36 CFR 219.13 - Coordination among Federal agencies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... AGRICULTURE PLANNING National Forest System Land and Resource Management Planning Collaborative Planning for Sustainability § 219.13 Coordination among Federal agencies. The responsible official must provide early and... proposed actions; (b) For the streamlined coordination of Federal agency policies, resource management...

  19. High rates of viral suppression in adults and children with high CD4+ counts using a streamlined ART delivery model in the SEARCH trial in rural Uganda and Kenya

    PubMed Central

    Kwarisiima, Dalsone; Kamya, Moses R.; Owaraganise, Asiphas; Mwangwa, Florence; Byonanebye, Dathan M.; Ayieko, James; Plenty, Albert; Black, Doug; Clark, Tamara D.; Nzarubara, Bridget; Snyman, Katherine; Brown, Lillian; Bukusi, Elizabeth; Cohen, Craig R.; Geng, Elvin H.; Charlebois, Edwin D.; Ruel, Theodore D.; Petersen, Maya L.; Havlir, Diane; Jain, Vivek

    2017-01-01

    Abstract Introduction: The 2015 WHO recommendation of antiretroviral therapy (ART) for all HIV-positive persons calls for treatment initiation in millions of persons newly eligible with high CD4+ counts. Efficient and effective care models are urgently needed for this population. We evaluated clinical outcomes of asymptomatic HIV-positive adults and children starting ART with high CD4+ counts using a novel streamlined care model in rural Uganda and Kenya. Methods: In the 16 intervention communities of the HIV test-and-treat Sustainable East Africa Research for Community Health Study (NCT01864603), all HIV-positive individuals irrespective of CD4 were offered ART (efavirenz [EFV]/tenofovir disoproxil fumarate + emtricitabine (FTC) or lamivudine (3TC). We studied adults (≥fifteen years) with CD4 ≥ 350/μL and children (two to fourteen years) with CD4 > 500/μL otherwise ineligible for ART by country guidelines. Clinics implemented a patient-centred streamlined care model designed to reduce patient-level barriers and maximize health system efficiency. It included (1) nurse-conducted visits with physician referral of complex cases, (2) multi-disease chronic care (including for hypertension/diabetes), (3) patient-centred, friendly staff, (4) viral load (VL) testing and counselling, (5) three-month return visits and ART refills, (6) appointment reminders, (7) tiered tracking for missed appointments, (8) flexible clinic hours (outside routine schedule) and (9) telephone access to clinicians. Primary outcomes were 48-week retention in care, viral suppression (% with measured week 48 VL ≤ 500 copies/mL) and adverse events. Results: Overall, 972 HIV-positive adults with CD4+ ≥ 350/μL initiated ART with streamlined care. Patients were 66% female and had median age thirty-four years (IQR, 28–42), CD4+ 608/μL (IQR, 487–788/μL) and VL 6775 copies/mL (IQR, <500–37,003 c/mL). At week 48, retention was 92% (897/972; 2 died/40 moved/8 withdrew/4 transferred care/21/964 [2%] were lost to follow-up). Viral suppression occurred in 778/838 (93%) and 800/972 (82%) in intention-to-treat analysis. Grade III/IV clinical/laboratory adverse events were rare: 95 occurred in 74/972 patients (7.6%). Only 8/972 adults (0.8%) switched ART from EFV to lopinavir (LPV) (n = 2 for dizziness, n = 2 for gynaecomastia, n = 4 for other reasons). Among 83 children, week 48 retention was 89% (74/83), viral suppression was 92% (65/71) and grade III/IV adverse events occurred in 4/83 (4.8%). Conclusions: Using a streamlined care model, viral suppression, retention and ART safety were high among asymptomatic East African adults and children with high CD4+ counts initiating treatment. Clinical Trial Number: NCT01864603 PMID:28770596

  20. Searching and Mining Visually Observed Phenotypes of Maize Mutants

    USDA-ARS?s Scientific Manuscript database

    There are thousands of maize mutants, which are invaluable resources for plant research. Geneticists use them to study underlying mechanisms of biochemistry, cell biology, cell development, and cell physiology. To streamline the understanding of such complex processes, researchers need the most curr...

  1. General Services Administration Streamlines the Procurement of Construction Services

    DTIC Science & Technology

    2010-05-01

    successful. The system must be changed to increase performance, and have a sustainable performance measurement system that results in an increase...currently employ, and what is needed to employ a sustainable performance measurement system that has accompanying increase in performance and value

  2. A streamlined build system foundation for developing HPC software

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    White, Chris; Harrison, Cyrus; Hornung, Richard

    2017-02-09

    BLT bundles custom CMake macros, unit testing frameworks for C++ and Fortran, and a set of smoke tests for common HPC dependencies. The combination of these three provides a foundation for quickly bootstrapping a CMale-based system for developing HPC softward.

  3. Technology in International Admissions

    ERIC Educational Resources Information Center

    White, Elizabeth

    2012-01-01

    In a relatively short time, technology applications have become an essential feature of the admissions business. They make the jobs of international admissions professionals easier in many ways, allowing for more robust communication with applicants and counselors, a streamlined application process, and quicker access to information about…

  4. Streamlining and integrating right-of-way and utility processes with planning, environmental, and design processes in Australia and Canada.

    DOT National Transportation Integrated Search

    2009-06-01

    Many transportation projects require acquisition of land and accommodation of utility facilities in the : right-of-way. The Federal Highway Administration, American Association of State Highway and : Transportation Officials, and National Cooperative...

  5. 77 FR 26785 - Implementation of Indian Reservation Roads Program and Streamlining the Federal Delivery of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... does not currently exist and needs to be constructed.'' A primary access route is the shortest feasible... Introductions 9:15 a.m.-10:45 a.m. Proposed/Access Roads (Recommendation, Expectations, Implementation) 10:45 a...

  6. Black raspberry genetic and genomic resources development

    USDA-ARS?s Scientific Manuscript database

    This study incorporates field and laboratory components to advance and streamline identification of a variety of traits of economic interest and to develop molecular markers for marker assisted breeding of black raspberry (Rubus occidentalis). A lack of adapted, disease resistant cultivars has led t...

  7. Speeding decisions. Social security's information exchange program.

    PubMed

    Winter, Kitt; Hastings, Bob

    2011-05-01

    The Social Security Administration has plenty of reasons to streamline its records request process-more than 15 million reasons each year, in fact. That's why it has been pioneering information exchange projects with the private sector, including use of the Nationwide Health Information Network.

  8. Development of 3D and 4D Bridge Models and Plans

    DOT National Transportation Integrated Search

    2018-05-28

    Since 2012, MDOT has been leading national efforts to modernize design development with 3D modeling. Early focus on roadway projects yielded streamlined plan production and digital data for construction. As MDOT pivots to 3D model-centric design, nat...

  9. Landslide!

    NASA Image and Video Library

    2017-05-12

    This image from NASA Mars Reconnaissance Orbiter shows a fresh well-preserved landslide scarp and rocky deposit off the edge of a streamlined mesa in Simud Valles, a giant outflow channel carved by ancient floods. A stereo anaglyph is available at https://photojournal.jpl.nasa.gov/catalog/PIA21633

  10. Descriptive Analysis of the Rip Entry in Competitive Diving.

    ERIC Educational Resources Information Center

    Brown, Janet G.; And Others

    1984-01-01

    Different types of diving entries were filmed both above water and underwater to help identify factors which enable divers to enter the water without apparent splash. Anthropometric measures of subjects were taken to determine body streamlining. Results are presented. (Author/DF)

  11. The Solution to Education Bureaucracies. The Iconoclast.

    ERIC Educational Resources Information Center

    McMurtry, John

    1996-01-01

    Observes that decisions to cut bureaucratic waste in Canada's educational system rests with the bureaucracy itself. Maintains that most schools could productively institute a limited form of teacher-oriented self-administration, thereby reducing and streamlining educational administration. Argues that most educational administration is…

  12. Validating commercial remote sensing and spatial information (CRS&SI) technologies for streamlining environmental and planning processes in transportation projects.

    DOT National Transportation Integrated Search

    2010-03-01

    Transportation corridor-planning processes are well understood, and consensus exists among practitioners : about common practices for stages and tasks included in traditional EIS approaches. However, traditional approaches do : not typically employ f...

  13. Remediation System Evaluation, Streamlined Remediation System Evaluation (RSE-Lite), Circuitron Corporation Superfund Site

    EPA Pesticide Factsheets

    The Circuitron Corporation Superfund Site is located at 82 Milbar Boulevard, East Farmingdale, Suffolk County, New York. The site is situated on a 1-acre lot in an industrial/commercial area that is surrounded by similar small manufacturers...

  14. Developing black raspberry genetic and genomic resources

    USDA-ARS?s Scientific Manuscript database

    This study incorporates field and laboratory components to advance and streamline identification of a variety of traits of economic interest and to develop molecular markers for marker assisted breeding of black raspberry (Rubus occidentalis). A lack of adapted, disease resistant cultivars has led t...

  15. Elementary Hemodynamic Principles Based on Modified Bernoulli's Equation.

    ERIC Educational Resources Information Center

    Badeer, Henry S.

    1985-01-01

    Develops and expands basic concepts of Bernoulli's equation as it applies to vascular hemodynamics. Simple models are used to illustrate gravitational potential energy, steady nonturbulent flow, pump-driven streamline flow, and other areas. Relationships to the circulatory system are also discussed. (DH)

  16. 77 FR 7214 - Notice of Availability: Programmatic Environmental Assessment for Mail Processing Network...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ... Network Rationalization Initiative (Formerly Known as the ``Network Optimization'' Initiative), Nationwide... Processing Network Rationalization Initiative (the ``Proposed Action''), which is national in scope. This PEA... Network Rationalization Initiative to create a more streamlined processing and distribution network using...

  17. Project inspection using mobile technology - phase I : an investigation into existing business processes and areas for improvement using mobile technology.

    DOT National Transportation Integrated Search

    2013-08-01

    As mobile technology becomes widely available and affordable, transportation agencies can use this technology to : streamline operations involved within project inspection. This research, conducted in two phases, identified : opportunities for proces...

  18. Streamlining the Process of Acquiring Secure Open Architecture Software Systems

    DTIC Science & Technology

    2013-10-08

    Microsoft.NET, Enterprise Java Beans, GNU Lesser General Public License (LGPL) libraries, and data communication protocols like the Hypertext Transfer...NetBeans development environments),  customer relationship management (SugarCRM),  database management systems (PostgreSQL, MySQL ),  operating

  19. Space Wire Upper Layer Protocols

    NASA Technical Reports Server (NTRS)

    Rakow, Glenn; Schnurr, Richard; Gilley, Daniel; Parkes, Steve

    2004-01-01

    This viewgraph presentation addresses efforts to provide a streamlined approach for developing SpaceWire Upper layer protocols which allows industry to drive standardized communication solutions for real projects. The presentation proposes a simple packet header that will allow flexibility in implementing a diverse range of protocols.

  20. A Streamline-Upwind Petrov-Galerkin Finite Element Scheme for Non-Ionized Hypersonic Flows in Thermochemical Nonequilibrium

    NASA Technical Reports Server (NTRS)

    Kirk, Benjamin S.; Bova, Stephen W.; Bond, Ryan B.

    2011-01-01

    Presentation topics include background and motivation; physical modeling including governing equations and thermochemistry; finite element formulation; results of inviscid thermal nonequilibrium chemically reacting flow and viscous thermal equilibrium chemical reacting flow; and near-term effort.

  1. Battling Budget Woes.

    ERIC Educational Resources Information Center

    Agron, Joe, Ed.

    1999-01-01

    Discusses how various school districts are addressing school quality on tight budgets. Options discussed include use of portable classrooms, streamlining non-educational services, leasing and performance contracting, and energy improvements and working with power utilities to cut costs. Argues for adopting and enforcing ISO 9000 standards to…

  2. WATERSHED CLASSIFICATION AS A DIAGNOSTIC TOOL FOR CONSOLIDATED ASSESSMENT AND LISTING PROGRAMS

    EPA Science Inventory

    With over 40,000 TMDLs scheduled for development, the states, tribes, and EPA Regions need efficient streamlined approaches for watershed level inventory, monitoring, condition assessment, diagnosis of impairment, and prioritization of watersheds for restoration and future load r...

  3. Desktop Publishing for Counselors.

    ERIC Educational Resources Information Center

    Lucking, Robert; Mitchum, Nancy

    1990-01-01

    Discusses the fundamentals of desktop publishing for counselors, including hardware and software systems and peripherals. Notes by using desktop publishing, counselors can produce their own high-quality documents without the expense of commercial printers. Concludes computers present a way of streamlining the communications of a counseling…

  4. 3 CFR 13571 - Executive Order 13571 of April 27, 2011. Streamlining Service Delivery and Improving Customer...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... performance against the best in business. This effort to “put people first” was an important step. It was... Office of Science and Technology Policy shall assist and support agencies in developing customer service...

  5. 48 CFR 1319.800 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... BUSINESS PROGRAMS Contracting With the Small Business Administration (the 8(a) Program) 1319.800 General. (a) By Partnership Agreement between the Small Business Administration (SBA) and the Department of... in accordance with the terms of the Partnership Agreement and take full advantage of the streamlined...

  6. 45 CFR 155.405 - Single streamlined application.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 155.405 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS EXCHANGE ESTABLISHMENT STANDARDS AND OTHER RELATED STANDARDS UNDER THE AFFORDABLE CARE ACT Exchange Functions in the Individual Market: Enrollment in Qualified Health Plans § 155.405 Single...

  7. 45 CFR 155.405 - Single streamlined application.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 155.405 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS EXCHANGE ESTABLISHMENT STANDARDS AND OTHER RELATED STANDARDS UNDER THE AFFORDABLE CARE ACT Exchange Functions in the Individual Market: Enrollment in Qualified Health Plans § 155.405 Single...

  8. Graphical simulation for aerospace manufacturing

    NASA Technical Reports Server (NTRS)

    Babai, Majid; Bien, Christopher

    1994-01-01

    Simulation software has become a key technological enabler for integrating flexible manufacturing systems and streamlining the overall aerospace manufacturing process. In particular, robot simulation and offline programming software is being credited for reducing down time and labor cost, while boosting quality and significantly increasing productivity.

  9. How streamlining telecommunications can cut IT expense.

    PubMed

    McIntyre, Greg

    2016-02-01

    Hospitals and health systems can save IT expenses by implementing more efficient processes in accordance with the principles of effective telecommunications expense management. This approach involves three primary steps: Inventory of existing infrastructure. Charge verification. Optimization of rates and design for continual improvement.

  10. U.S. DOE Office of Science Success Stories (2011)

    Science.gov Websites

    ; Gibson, Kerry; ACC0400 2011-04-01; Thin Sheet of Diamond Has Worlds of Uses; Sagoff, Jared; ACC0399 Top -03-28; Firm Uses DOE's Fastest Supercomputer to Streamline Long-Haul Trucks; ACC0391 2011-03-28

  11. 20180312 - Uncertainty and Variability in High-Throughput Toxicokinetics for Risk Prioritization (SOT)

    EPA Science Inventory

    Streamlined approaches that use in vitro experimental data to predict chemical toxicokinetics (TK) are increasingly being used to perform risk-based prioritization based upon dosimetric adjustment of high-throughput screening (HTS) data across thousands of chemicals. However, ass...

  12. Researched applied to transonic compressors in numerical fluid mechanics of inviscid flow and viscous flow

    NASA Technical Reports Server (NTRS)

    Thompkins, W. T., Jr.

    1985-01-01

    A streamline Euler solver which combines high accuracy and good convergence rates with capabilities for inverse or direct mode solution modes and an analysis technique for finite difference models of hyperbolic partial difference equations were developed.

  13. The Cassini Solstice Mission: Streamlining Operations by Sequencing with PIEs

    NASA Technical Reports Server (NTRS)

    Vandermey, Nancy; Alonge, Eleanor K.; Magee, Kari; Heventhal, William

    2014-01-01

    The Cassini Solstice Mission (CSM) is the second extended mission phase of the highly successful Cassini/Huygens mission to Saturn. Conducted at a much-reduced funding level, operations for the CSM have been streamlined and simplified significantly. Integration of the science timeline, which involves allocating observation time in a balanced manner to each of the five different science disciplines (with representatives from the twelve different science instruments), has long been a labor-intensive endeavor. Lessons learned from the prime mission (2004-2008) and first extended mission (Equinox mission, 2008-2010) were utilized to design a new process involving PIEs (Pre-Integrated Events) to ensure the highest priority observations for each discipline could be accomplished despite reduced work force and overall simplification of processes. Discipline-level PIE lists were managed by the Science Planning team and graphically mapped to aid timeline deconfliction meetings prior to assigning discrete segments of time to the various disciplines. Periapse segments are generally discipline-focused, with the exception of a handful of PIEs. In addition to all PIEs being documented in a spreadsheet, allocated out-of-discipline PIEs were entered into the Cassini Information Management System (CIMS) well in advance of timeline integration. The disciplines were then free to work the rest of the timeline internally, without the need for frequent interaction, debate, and negotiation with representatives from other disciplines. As a result, the number of integration meetings has been cut back extensively, freeing up workforce. The sequence implementation process was streamlined as well, combining two previous processes (and teams) into one. The new Sequence Implementation Process (SIP) schedules 22 weeks to build each 10-week-long sequence, and only 3 sequence processes overlap. This differs significantly from prime mission during which 5-week-long sequences were built in 24 weeks, with 6 overlapping processes.

  14. Streamlining Safety Data Collection in Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia Trials: Recommendations of the Clinical Trials Transformation Initiative Antibacterial Drug Development Project Team.

    PubMed

    Donnelly, Helen; Alemayehu, Demissie; Botgros, Radu; Comic-Savic, Sabrina; Eisenstein, Barry; Lorenz, Benjamin; Merchant, Kunal; Pelfrene, Eric; Reith, Christina; Santiago, Jonas; Tiernan, Rosemary; Wunderink, Richard; Tenaerts, Pamela; Knirsch, Charles

    2016-08-15

    Resistant bacteria are one of the leading causes of hospital-acquired/ventilator-associated bacterial pneumonia (HABP/VABP). HABP/VABP trials are complex and difficult to conduct due to the large number of medical procedures, adverse events, and concomitant medications involved. Differences in the legislative frameworks between different regions of the world may also lead to excessive data collection. The Clinical Trials Transformation Initiative (CTTI) seeks to advance antibacterial drug development (ABDD) by streamlining clinical trials to improve efficiency and feasibility while maintaining ethical rigor, patient safety, information value, and scientific validity. In 2013, CTTI engaged a multidisciplinary group of experts to discuss challenges impeding the conduct of HABP/VABP trials. Separate workstreams identified challenges associated with current data collection processes. Experts defined "data collection" as the act of capturing and reporting certain data on the case report form as opposed to recording of data as part of routine clinical care. The ABDD Project Team developed strategies for streamlining safety data collection in HABP/VABP trials using a Quality by Design approach. Current safety data collection processes in HABP/VABP trials often include extraneous information. More targeted strategies for safety data collection in HABP/VABP trials will rely on optimal protocol design and prespecification of which safety data are essential to satisfy regulatory reporting requirements. A consensus and a cultural change in clinical trial design and conduct, which involve recognition of the need for more efficient data collection, are urgently needed to advance ABDD and to improve HABP/VABP trials in particular. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sarman, Sten, E-mail: sarman@ownit.nu; Wang, Yong-Lei; Laaksonen, Aatto

    The self-diffusion coefficients of nematic phases of various model systems consisting of regular convex calamitic and discotic ellipsoids and non-convex bodies such as bent-core molecules and soft ellipsoid strings have been obtained as functions of the shear rate in a shear flow. Then the self-diffusion coefficient is a second rank tensor with three different diagonal components and two off-diagonal components. These coefficients were found to be determined by a combination of two mechanisms, which previously have been found to govern the self-diffusion of shearing isotropic liquids, namely, (i) shear alignment enhancing the diffusion in the direction parallel to the streamlinesmore » and hindering the diffusion in the perpendicular directions and (ii) the distortion of the shell structure in the liquid whereby a molecule more readily can escape from a surrounding shell of nearest neighbors, so that the mobility increases in every direction. Thus, the diffusion parallel to the streamlines always increases with the shear rate since these mechanisms cooperate in this direction. In the perpendicular directions, these mechanisms counteract each other so that the behaviour becomes less regular. In the case of the nematic phases of the calamitic and discotic ellipsoids and of the bent core molecules, mechanism (ii) prevails so that the diffusion coefficients increase. However, the diffusion coefficients of the soft ellipsoid strings decrease in the direction of the velocity gradient because the broadsides of these molecules are oriented perpendicularly to this direction due the shear alignment (i). The cross coupling coefficient relating a gradient of tracer particles in the direction of the velocity gradient and their flow in the direction of the streamlines is negative and rather large, whereas the other coupling coefficient relating a gradient in the direction of the streamlines and a flow in the direction of the velocity gradient is very small.« less

  16. "Speeding up the road to recovery": The Complex Recovery Assessment and Consultation (CRAC) service.

    PubMed

    Davis Le Brun, Stephanie

    2015-01-01

    The number of bed closures in mental health is on the rise, creating additional pressure on services, including acute mental health services. An efficient way of working is required in order to streamline the acute care pathway and decrease unnecessary delays to length of stay, ensuring all individuals can be offered an inpatient bed when in crisis. The Complex Recovery Assessment and Consultation (CRAC) service was created in order to support acute mental health inpatient clinicians in streamlining hospital stays for service users who present with complex presentations that require lengthier admissions (over 40 days) by offering assessment, advice, and intervention from a rehabilitation perspective. The team was also created to understand why individuals may require a lengthy hospital stay. Preliminary data showed that requiring a placement on discharge proved to be the most significant factor in increased length of stay and so the team took on a new role of discharge coordinator after around a year of operating. This involved assisting in decreasing any delays out of hospital through improved communication and dedicated time to complete tasks, such as completing paperwork for placement referrals and funding panels. Since taking on this role it was found that the time taken for individuals to be discharged to a rehabilitation or specialist placement decreased; a rehabilitation placement by 13.12 days and a specialist placement by 9.22 days. Discharge to a family address also decreased by 2.9 days and a home address by 2.47 days. Those patients with complex presentations benefit from having one dedicated team to coordinate the discharge process. Their lengthier acute inpatient stay is improved through streamlining care pathways, ultimately decreasing delays in discharge.

  17. Ancient Streamlined Islands of the Palos Outflow Channel

    NASA Image and Video Library

    2016-08-24

    This image shows the northern terminus of an outflow channel located in the volcanic terrains of Amenthes Planum. The channel sources from the Palos impact crater to the south, where water flowed into the crater from Tinto Vallis and eventually formed a paleo lake. As rising lake levels breached through the crater's rim and inundated the plains to the north, the resulting high velocity, large discharge floods plucked out and eroded the volcanic plains scouring out the "Palos Outflow Channel" and the streamlined mesa-islands on its floor. These streamlined forms are the eroded remnants of plains material sculpted by catastrophic floods and are not sediment deposits emplaced by lower magnitude stream flows. Both the fluvial channel floor and the volcanic island surfaces are densely cratered by impacts suggesting that both the surfaces and the flood events are ancient. The morphology (shape) of the channel system and its islands have been preserved through the eons, but water has long been absent from this drainage system. Since then, winds have transported light-toned sediments across this terrain forming extensive dune fields within the channel system, on the floors of impact craters, and in other protected locations in the Palos Outflow Channel region. A closer look shows chevron, or fish-bone shaped, light-toned dunes located near the top of the image where numerous smaller channels have cut through the landscape. These dunes likely started out as Transverse Aeolian Ridges (TAR) that form perpendicular to the prevailing wind direction where the wind-blown sediment supply is scarce. This intriguing morphology likely reflects changes in the prevailing wind environment over time. http://photojournal.jpl.nasa.gov/catalog/PIA21023

  18. Facilitating interprofessional evidence-based practice in paediatric rehabilitation: development, implementation and evaluation of an online toolkit for health professionals.

    PubMed

    Glegg, Stephanie M N; Livingstone, Roslyn; Montgomery, Ivonne

    2016-01-01

    Lack of time, competencies, resources and supports are documented as barriers to evidence-based practice (EBP). This paper introduces a recently developed web-based toolkit designed to assist interprofessional clinicians in implementing EBP within a paediatric rehabilitation setting. EBP theory, models, frameworks and tools were applied or adapted in the development of the online resources, which formed the basis of a larger support strategy incorporating interactive workshops, knowledge broker facilitation and mentoring. The highly accessed toolkit contains flowcharts with embedded information sheets, resources and templates to streamline, quantify and document outcomes throughout the EBP process. Case examples relevance to occupational therapy and physical therapy highlight the utility and application of the toolkit in a clinical paediatric setting. Workshops were highly rated by learners for clinical relevance, presentation level and effectiveness. Eight evidence syntheses have been created and 79 interventions have been evaluated since the strategy's inception in January 2011. The toolkit resources streamlined and supported EBP processes, promoting consistency in quality and presentation of outputs. The online toolkit can be a useful tool to facilitate clinicians' use of EBP in order to meet the needs of the clients and families whom they support. Implications for Rehabilitation A comprehensive online EBP toolkit for interprofessional clinicians is available to streamline the EBP process and to support learning needs regardless of competency level. Multi-method facilitation support, including interactive education, e-learning, clinical librarian services and knowledge brokering, is a valued but cost-restrictive supplement to the implementation of online EBP resources. EBP resources are not one-size-fits-all; targeted appraisal tools, models and frameworks may be integrated to improve their utility for specific sectors, which may limit them for others.

  19. A streamlined sustainability assessment tool for improved decision making in the urban water industry.

    PubMed

    Schulz, Matthias; Short, Michael D; Peters, Gregory M

    2012-01-01

    Water supply is a key consideration in sustainable urban planning. Ideally, detailed quantitative sustainability assessments are undertaken during the planning stage to inform the decision-making process. In reality, however, the significant time and cost associated with undertaking such detailed environmental and economic assessments is often cited as a barrier to wider implementation of these key decision support tools, particularly for decisions made at the local or regional government level. In an attempt to overcome this barrier of complexity, 4 water service providers in Melbourne, Australia, funded the development of a publicly available streamlined Environmental Sustainability Assessment Tool, which is aimed at a wide range of decision makers to assist them in broadening the type and number of water servicing options that can be considered for greenfield or backlog developments. The Environmental Sustainability Assessment Tool consists of a simple user interface and draws on life cycle inventory data to allow for rapid estimation of the environmental and economic performance of different water servicing scenarios. Scenario options can then be further prioritized by means of an interactive multicriteria analysis. The intent of this article is to identify the key issues to be considered in a streamlined sustainability assessment tool for the urban water industry, and to demonstrate the feasibility of generating accurate life cycle assessments and life cycle costings, using such a tool. We use a real-life case study example consisting of 3 separate scenarios for a planned urban development to show that this kind of tool can emulate life cycle assessments and life cycle costings outcomes obtained through more detailed studies. This simplified approach is aimed at supporting "sustainability thinking" early in the decision-making process, thereby encouraging more sustainable water and sewerage infrastructure solutions. Copyright © 2011 SETAC.

  20. Reconstruction of muscle fascicle architecture from iodine-enhanced microCT images: A combined texture mapping and streamline approach.

    PubMed

    Kupczik, Kornelius; Stark, Heiko; Mundry, Roger; Neininger, Fabian T; Heidlauf, Thomas; Röhrle, Oliver

    2015-10-07

    Skeletal muscle models are used to investigate motion and force generation in both biological and bioengineering research. Yet, they often lack a realistic representation of the muscle's internal architecture which is primarily composed of muscle fibre bundles, known as fascicles. Recently, it has been shown that fascicles can be resolved with micro-computed tomography (µCT) following staining of the muscle tissue with iodine potassium iodide (I2KI). Here, we present the reconstruction of the fascicular spatial arrangement and geometry of the superficial masseter muscle of a dog based on a combination of pattern recognition and streamline computation. A cadaveric head of a dog was incubated in I2KI and µCT-scanned. Following segmentation of the masseter muscle a statistical pattern recognition algorithm was applied to create a vector field of fascicle directions. Streamlines were then used to transform the vector field into a realistic muscle fascicle representation. The lengths of the reconstructed fascicles and the pennation angles in two planes (frontal and sagittal) were extracted and compared against a tracked fascicle field obtained through cadaver dissection. Both fascicle lengths and angles were found to vary substantially within the muscle confirming the complex and heterogeneous nature of skeletal muscle described by previous studies. While there were significant differences in the pennation angle between the experimentally derived and µCT-reconstructed data, there was congruence in the fascicle lengths. We conclude that the presented approach allows for embedding realistic fascicle information into finite element models of skeletal muscles to better understand the functioning of the musculoskeletal system. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Use of Mobile Devices and the Internet for Multimedia Informed Consent Delivery and Data Entry in a Pediatric Asthma Trial: Study Design and Rationale

    PubMed Central

    Blake, Kathryn; Holbrook, Janet T.; Antal, Holly; Shade, David; Bunnell, H. Timothy; McCahan, Suzanne M.; Wise, Robert A.; Pennington, Chris; Garfinkel, Paul; Wysocki, Tim

    2015-01-01

    Introduction Phase III / IV clinical trials are expensive and time consuming and often suffer from poor enrollment and retention rates. Pediatric trials are particularly difficult because scheduling around the parent, participant and potentially other sibling schedules can be burdensome. We are evaluating using the internet and mobile devices to conduct the consent process and study visits in a streamlined pediatric asthma trial. Our hypothesis is that these study processes will be noninferior and will be less expensive compared to a traditional pediatric asthma trial. Materials/Methods Parents and participants, aged 12 through 17 years, complete the informed consent process by viewing a multi-media website containing a consent video and study material in the streamlined trial. Participants are provided an iPad with WiFi and EasyOne spirometer for use during FaceTime visits and online twice daily symptom reporting during an 8-week run-in followed by 12-week study period. Outcomes are compared with participants completing a similarly designed traditional trial comparing the same treatments within the same pediatric health-system. After 8 weeks of open-label Advair 250/50 twice daily, participants in both trial types are randomized to Advair 250/50, Flovent 250, or Advair 100/50 given 1 inhalation twice daily. Study staff track time spent to determine study costs. Results Participants have been enrolled in the streamlined and traditional trials and recuitment is ongoing. Conclusions This project will provide important information on both clinical and economic outcomes for a novel method of conducting clinical trials. The results will be broadly applicable to trials of other diseases. PMID:25847579

  2. Streamlining plant sample preparation: the use of high-throughput robotics to process echinacea samples for biomarker profiling by MALDI-TOF mass spectrometry.

    PubMed

    Greene, Leasa A; Isaac, Issa; Gray, Dean E; Schwartz, Sarah A

    2007-09-01

    Several species in the genus Echinacea are beneficial herbs popularly used for many ailments. The most popular Echinacea species for cultivation, wild collection, and herbal products include E. purpurea (L.) Moench, E. pallida (Nutt.) Nutt., and E. angustifolia (DC). Product adulteration is a key concern for the natural products industry, where botanical misidentification and introduction of other botanical and nonbotanical contaminants exist throughout the formulation and production process. Therefore, rapid and cost-effective methods that can be used to monitor these materials for complex product purity and consistency are of benefit to consumers and producers. The objective of this continuing research was to develop automated, high-throughput processing methods that, teamed with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis, differentiate Echinacea species by their mass profiles. Small molecules, peptide, and proteins from aerial parts (leaf/stem/flowers), seeds, and roots from E. purpurea and E. angustifolia; seeds and roots from E. pallida; and off-the-shelf Echinacea supplements were extracted and analyzed by MS using methods developed on the ProPrep liquid handling system (Genomic Solutions). Analysis of these samples highlighted key MS signal patterns from both small molecules and proteins that characterized the individual Echinacea materials analyzed. Based on analysis of pure Echinacea samples, off-the-shelf products containing Echinacea could then be evaluated in a streamlined process. Corresponding analysis of dietary supplements was used to monitor for product composition, including Echinacea species and plant materials used. These results highlight the potential for streamlined, automated approaches for agricultural species differentiation and botanical product evaluation.

  3. Migration of finite sized particles in a laminar square channel flow from low to high Reynolds numbers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abbas, M., E-mail: micheline.abbas@ensiacet.fr; CNRS, Fédération de recherche FERMaT, CNRS, 31400, Toulouse; Magaud, P.

    2014-12-15

    The migration of neutrally buoyant finite sized particles in a Newtonian square channel flow is investigated in the limit of very low solid volumetric concentration, within a wide range of channel Reynolds numbers Re = [0.07-120]. In situ microscope measurements of particle distributions, taken far from the channel inlet (at a distance several thousand times the channel height), revealed that particles are preferentially located near the channel walls at Re > 10 and near the channel center at Re < 1. Whereas the cross-streamline particle motion is governed by inertia-induced lift forces at high inertia, it seems to be controlledmore » by shear-induced particle interactions at low (but finite) Reynolds numbers, despite the low solid volume fraction (<1%). The transition between both regimes is observed in the range Re = [1-10]. In order to exclude the effect of multi-body interactions, the trajectories of single freely moving particles are calculated thanks to numerical simulations based on the force coupling method. With the deployed numerical tool, the complete particle trajectories are accessible within a reasonable computational time only in the inertial regime (Re > 10). In this regime, we show that (i) the particle undergoes cross-streamline migration followed by a cross-lateral migration (parallel to the wall) in agreement with previous observations, and (ii) the stable equilibrium positions are located at the midline of the channel faces while the diagonal equilibrium positions are unstable. At low flow inertia, the first instants of the numerical simulations (carried at Re = O(1)) reveal that the cross-streamline migration of a single particle is oriented towards the channel wall, suggesting that the particle preferential positions around the channel center, observed in the experiments, are rather due to multi-body interactions.« less

  4. Use of mobile devices and the internet for multimedia informed consent delivery and data entry in a pediatric asthma trial: Study design and rationale.

    PubMed

    Blake, Kathryn; Holbrook, Janet T; Antal, Holly; Shade, David; Bunnell, H Timothy; McCahan, Suzanne M; Wise, Robert A; Pennington, Chris; Garfinkel, Paul; Wysocki, Tim

    2015-05-01

    Phase III/IV clinical trials are expensive and time consuming and often suffer from poor enrollment and retention rates. Pediatric trials are particularly difficult because scheduling around the parent, participant and potentially other sibling schedules can be burdensome. We are evaluating using the internet and mobile devices to conduct the consent process and study visits in a streamlined pediatric asthma trial. Our hypothesis is that these study processes will be non-inferior and will be less expensive compared to a traditional pediatric asthma trial. Parents and participants, aged 12 through 17 years, complete the informed consent process by viewing a multi-media website containing a consent video and study material in the streamlined trial. Participants are provided an iPad with WiFi and EasyOne spirometer for use during FaceTime visits and online twice daily symptom reporting during an 8-week run-in followed by a 12-week study period. Outcomes are compared with participants completing a similarly designed traditional trial comparing the same treatments within the same pediatric health-system. After 8 weeks of open-label Advair 250/50 twice daily, participants in both trial types are randomized to Advair 250/50, Flovent 250, or Advair 100/50 given 1 inhalation twice daily. Study staff track time spent to determine study costs. Participants have been enrolled in the streamlined and traditional trials and recruitment is ongoing. This project will provide important information on both clinical and economic outcomes for a novel method of conducting clinical trials. The results will be broadly applicable to trials of other diseases. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Design, development and clinical validation of computer-aided surgical simulation system for streamlined orthognathic surgical planning.

    PubMed

    Yuan, Peng; Mai, Huaming; Li, Jianfu; Ho, Dennis Chun-Yu; Lai, Yingying; Liu, Siting; Kim, Daeseung; Xiong, Zixiang; Alfi, David M; Teichgraeber, John F; Gateno, Jaime; Xia, James J

    2017-12-01

    There are many proven problems associated with traditional surgical planning methods for orthognathic surgery. To address these problems, we developed a computer-aided surgical simulation (CASS) system, the AnatomicAligner, to plan orthognathic surgery following our streamlined clinical protocol. The system includes six modules: image segmentation and three-dimensional (3D) reconstruction, registration and reorientation of models to neutral head posture, 3D cephalometric analysis, virtual osteotomy, surgical simulation, and surgical splint generation. The accuracy of the system was validated in a stepwise fashion: first to evaluate the accuracy of AnatomicAligner using 30 sets of patient data, then to evaluate the fitting of splints generated by AnatomicAligner using 10 sets of patient data. The industrial gold standard system, Mimics, was used as the reference. When comparing the results of segmentation, virtual osteotomy and transformation achieved with AnatomicAligner to the ones achieved with Mimics, the absolute deviation between the two systems was clinically insignificant. The average surface deviation between the two models after 3D model reconstruction in AnatomicAligner and Mimics was 0.3 mm with a standard deviation (SD) of 0.03 mm. All the average surface deviations between the two models after virtual osteotomy and transformations were smaller than 0.01 mm with a SD of 0.01 mm. In addition, the fitting of splints generated by AnatomicAligner was at least as good as the ones generated by Mimics. We successfully developed a CASS system, the AnatomicAligner, for planning orthognathic surgery following the streamlined planning protocol. The system has been proven accurate. AnatomicAligner will soon be available freely to the boarder clinical and research communities.

  6. Streamlined bioreactor-based production of human cartilage tissues.

    PubMed

    Tonnarelli, B; Santoro, R; Adelaide Asnaghi, M; Wendt, D

    2016-05-27

    Engineered tissue grafts have been manufactured using methods based predominantly on traditional labour-intensive manual benchtop techniques. These methods impart significant regulatory and economic challenges, hindering the successful translation of engineered tissue products to the clinic. Alternatively, bioreactor-based production systems have the potential to overcome such limitations. In this work, we present an innovative manufacturing approach to engineer cartilage tissue within a single bioreactor system, starting from freshly isolated human primary chondrocytes, through the generation of cartilaginous tissue grafts. The limited number of primary chondrocytes that can be isolated from a small clinically-sized cartilage biopsy could be seeded and extensively expanded directly within a 3D scaffold in our perfusion bioreactor (5.4 ± 0.9 doublings in 2 weeks), bypassing conventional 2D expansion in flasks. Chondrocytes expanded in 3D scaffolds better maintained a chondrogenic phenotype than chondrocytes expanded on plastic flasks (collagen type II mRNA, 18-fold; Sox-9, 11-fold). After this "3D expansion" phase, bioreactor culture conditions were changed to subsequently support chondrogenic differentiation for two weeks. Engineered tissues based on 3D-expanded chondrocytes were more cartilaginous than tissues generated from chondrocytes previously expanded in flasks. We then demonstrated that this streamlined bioreactor-based process could be adapted to effectively generate up-scaled cartilage grafts in a size with clinical relevance (50 mm diameter). Streamlined and robust tissue engineering processes, as the one described here, may be key for the future manufacturing of grafts for clinical applications, as they facilitate the establishment of compact and closed bioreactor-based production systems, with minimal automation requirements, lower operating costs, and increased compliance to regulatory guidelines.

  7. Dynamic Investigation of Release Characteristics of a Streamlined Internal Store from a Simulated Bomb Bay of the Republic F-105 Airplane at Mach Numbers of 0.8, 1.4, and 1.98, Coord. No. AF-222

    NASA Technical Reports Server (NTRS)

    Lee, John B.

    1956-01-01

    An investigation has been conducted in the 27- by 27-inch preflight jet of the Langley Pilotless Aircraft Research Station at Wallops Island, Va., of the release characteristics of a dynamically scaled streamlined-type internally carried store from a simulated bomb bay at Mach numbers M(sub o) of 0.8, 1.4, and 1.98. A l/17-scale model of the Republic F-105 half-fuselage and bomb-bay configuration was used with a streamlined store shape of a fineness ratio of 6.00. Simulated altitudes were 3,400 feet at M(sub o) = 0.8, 3,400, and 29,000 feet at M(sub o) = 1.4, and 29,000 feet at M(sub o) = 1.98. At supersonic speeds, high pitching moments are induced on the store in the vicinity of the bomb bay at high dynamic pressures. Successful ejections could not be made with the original configuration at supersonic speeds at near sea-level conditions. The pitching moments caused by unsymmetrical pressures on the store in a disturbed flow field were overcome by replacing the high-aspect-ratio fin with a low-aspect-ratio fin that had a 30-percent area increase which was less subject to aeroelastic effects. Release characteristics of the store were improved by orienting the fins so that they were in a more uniform flow field at the point of store release. The store pitching moments were shown to be reduced by increasing the simulated altitude. Favorable ejections were made at subsonic speeds at near sea-level conditions.

  8. Streamlining cardiovascular clinical trials to improve efficiency and generalisability.

    PubMed

    Zannad, Faiez; Pfeffer, Marc A; Bhatt, Deepak L; Bonds, Denise E; Borer, Jeffrey S; Calvo-Rojas, Gonzalo; Fiore, Louis; Lund, Lars H; Madigan, David; Maggioni, Aldo Pietro; Meyers, Catherine M; Rosenberg, Yves; Simon, Tabassome; Stough, Wendy Gattis; Zalewski, Andrew; Zariffa, Nevine; Temple, Robert

    2017-08-01

    Controlled trials provide the most valid determination of the efficacy and safety of an intervention, but large cardiovascular clinical trials have become extremely costly and complex, making it difficult to study many important clinical questions. A critical question, and the main objective of this review, is how trials might be simplified while maintaining randomisation to preserve scientific integrity and unbiased efficacy assessments. Experience with alternative approaches is accumulating, specifically with registry-based randomised controlled trials that make use of data already collected. This approach addresses bias concerns while still capitalising on the benefits and efficiencies of a registry. Several completed or ongoing trials illustrate the feasibility of using registry-based controlled trials to answer important questions relevant to daily clinical practice. Randomised trials within healthcare organisation databases may also represent streamlined solutions for some types of investigations, although data quality (endpoint assessment) is likely to be a greater concern in those settings. These approaches are not without challenges, and issues pertaining to informed consent, blinding, data quality and regulatory standards remain to be fully explored. Collaboration among stakeholders is necessary to achieve standards for data management and analysis, to validate large data sources for use in randomised trials, and to re-evaluate ethical standards to encourage research while also ensuring that patients are protected. The rapidly evolving efforts to streamline cardiovascular clinical trials have the potential to lead to major advances in promoting better care and outcomes for patients with cardiovascular disease. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  9. Design, development and clinical validation of computer-aided surgical simulation system for streamlined orthognathic surgical planning

    PubMed Central

    Yuan, Peng; Mai, Huaming; Li, Jianfu; Ho, Dennis Chun-Yu; Lai, Yingying; Liu, Siting; Kim, Daeseung; Xiong, Zixiang; Alfi, David M.; Teichgraeber, John F.; Gateno, Jaime

    2017-01-01

    Purpose There are many proven problems associated with traditional surgical planning methods for orthognathic surgery. To address these problems, we developed a computer-aided surgical simulation (CASS) system, the AnatomicAligner, to plan orthognathic surgery following our streamlined clinical protocol. Methods The system includes six modules: image segmentation and three-dimensional (3D) reconstruction, registration and reorientation of models to neutral head posture, 3D cephalometric analysis, virtual osteotomy, surgical simulation, and surgical splint generation. The accuracy of the system was validated in a stepwise fashion: first to evaluate the accuracy of AnatomicAligner using 30 sets of patient data, then to evaluate the fitting of splints generated by AnatomicAligner using 10 sets of patient data. The industrial gold standard system, Mimics, was used as the reference. Result When comparing the results of segmentation, virtual osteotomy and transformation achieved with AnatomicAligner to the ones achieved with Mimics, the absolute deviation between the two systems was clinically insignificant. The average surface deviation between the two models after 3D model reconstruction in AnatomicAligner and Mimics was 0.3 mm with a standard deviation (SD) of 0.03 mm. All the average surface deviations between the two models after virtual osteotomy and transformations were smaller than 0.01 mm with a SD of 0.01 mm. In addition, the fitting of splints generated by AnatomicAligner was at least as good as the ones generated by Mimics. Conclusion We successfully developed a CASS system, the AnatomicAligner, for planning orthognathic surgery following the streamlined planning protocol. The system has been proven accurate. AnatomicAligner will soon be available freely to the boarder clinical and research communities. PMID:28432489

  10. Effect of thyroxine on brain microstructure in extremely premature babies: magnetic resonance imaging findings in the TIPIT study.

    PubMed

    Ng, Sze May; Turner, Mark A; Gamble, Carrol; Didi, Mohammed; Victor, Suresh; Atkinson, Jessica; Sluming, Vanessa; Parkes, Laura M; Tietze, Anna; Abernethy, Laurence J; Weindling, Alan Michael

    2014-08-01

    In order to assess relationships between thyroid hormone status and findings on brain MRI, a subset of babies was recruited to a multi-centre randomised, placebo-controlled trial of levothyroxine (LT4) supplementation for babies born before 28 weeks' gestation (known as the TIPIT study, for Thyroxine supplementation In Preterm InfanTs). These infants were imaged at term-equivalence. Forty-five TIPIT participants had brain MRI using diffusion tensor imaging (DTI) to estimate white matter development by apparent diffusion coefficient (ADC), fractional anisotropy (FA) and tractography metrics of number and length of streamlines. We made comparisons between babies with the lowest and highest plasma FT4 concentrations during the initial 4 weeks after birth. There were no differences in DTI metrics between babies who had received LT4 supplementation and those who had received a placebo. Among recipients of a placebo, babies in the lowest quartile of plasma-free thyroxine (FT4) concentrations had significantly higher apparent diffusion coefficient measurements in the posterior corpus callosum and streamlines that were shorter and less numerous in the right internal capsule. Among LT4-supplemented babies, those who had plasma FT4 concentrations in the highest quartile had significantly lower apparent diffusion coefficient values in the left occipital lobe, higher fractional anisotropy in the anterior corpus callosum and longer and more numerous streamlines in the anterior corpus callosum. DTI variables were not associated with allocation of placebo or thyroid supplementation. Markers of poorly organised brain microstructure were associated with low plasma FT4 concentrations after birth. The findings suggest that plasma FT4 concentrations affect brain development in very immature infants and that the effect of LT4 supplementation for immature babies with low FT4 plasma concentrations warrants further study.

  11. Shape variation in the least killifish: ecological associations of phenotypic variation and the effects of a common garden.

    PubMed

    Landy, J Alex; Travis, Joseph

    2015-12-01

    Studies of the adaptive significance of variation among conspecific populations often focus on a single ecological factor. However, habitats rarely differ in only a single ecological factor, creating a challenge for identifying the relative importance of the various ecological factors that might be maintaining local adaptation. Here we investigate the ecological factors associated with male body shape variation among nine populations of the poeciliid fish, Heterandria formosa, from three distinct habitats and combine those results with a laboratory study of three of those populations to assess the contributions of genetic and environmental influences to shape variation. Field-collected animals varied principally in three ways: the orientation of the gonopodium, the intromittent organ; the degree of body depth and streamlining; and the shape of the tail musculature. Fish collected in the spring season were larger and had a more anteriorly positioned gonopodium than fish collected in autumn. Fish collected from lotic springs were larger and more streamlined than those collected from lentic ponds or tidal marshes. Some of the variation in male shape among populations within habitats was associated with population-level variation in species richness, adult density, vegetative cover, predation risk, and female standard length. Population-level differences among males in body size, position of the gonopodium, and shape of the tail musculature were maintained among males reared in a common environment. In contrast, population variation in the degree of streamlining was eliminated when males were reared in a common environment. These results illustrate the complicated construction of multivariate phenotypic variation and suggest that different agents of selection have acted on different components of shape.

  12. Streamlined research funding using short proposals and accelerated peer review: an observational study.

    PubMed

    Barnett, Adrian G; Herbert, Danielle L; Campbell, Megan; Daly, Naomi; Roberts, Jason A; Mudge, Alison; Graves, Nicholas

    2015-02-07

    Despite the widely recognised importance of sustainable health care systems, health services research remains generally underfunded in Australia. The Australian Centre for Health Services Innovation (AusHSI) is funding health services research in the state of Queensland. AusHSI has developed a streamlined protocol for applying and awarding funding using a short proposal and accelerated peer review. An observational study of proposals for four health services research funding rounds from May 2012 to November 2013. A short proposal of less than 1,200 words was submitted using a secure web-based portal. The primary outcome measures are: time spent preparing proposals; a simplified scoring of grant proposals (reject, revise or accept for interview) by a scientific review committee; and progressing from submission to funding outcomes within eight weeks. Proposals outside of health services research were deemed ineligible. There were 228 eligible proposals across 4 funding rounds: from 29% to 79% were shortlisted and 9% to 32% were accepted for interview. Success rates increased from 6% (in 2012) to 16% (in 2013) of eligible proposals. Applicants were notified of the outcomes within two weeks from the interview; which was a maximum of eight weeks after the submission deadline. Applicants spent 7 days on average preparing their proposal. Applicants with a ranking of reject or revise received written feedback and suggested improvements for their proposals, and resubmissions composed one third of the 2013 rounds. The AusHSI funding scheme is a streamlined application process that has simplified the process of allocating health services research funding for both applicants and peer reviewers. The AusHSI process has minimised the time from submission to notification of funding outcomes.

  13. Advanced in Visualization of 3D Time-Dependent CFD Solutions

    NASA Technical Reports Server (NTRS)

    Lane, David A.; Lasinski, T. A. (Technical Monitor)

    1995-01-01

    Numerical simulations of complex 3D time-dependent (unsteady) flows are becoming increasingly feasible because of the progress in computing systems. Unfortunately, many existing flow visualization systems were developed for time-independent (steady) solutions and do not adequately depict solutions from unsteady flow simulations. Furthermore, most systems only handle one time step of the solutions individually and do not consider the time-dependent nature of the solutions. For example, instantaneous streamlines are computed by tracking the particles using one time step of the solution. However, for streaklines and timelines, particles need to be tracked through all time steps. Streaklines can reveal quite different information about the flow than those revealed by instantaneous streamlines. Comparisons of instantaneous streamlines with dynamic streaklines are shown. For a complex 3D flow simulation, it is common to generate a grid system with several millions of grid points and to have tens of thousands of time steps. The disk requirement for storing the flow data can easily be tens of gigabytes. Visualizing solutions of this magnitude is a challenging problem with today's computer hardware technology. Even interactive visualization of one time step of the flow data can be a problem for some existing flow visualization systems because of the size of the grid. Current approaches for visualizing complex 3D time-dependent CFD solutions are described. The flow visualization system developed at NASA Ames Research Center to compute time-dependent particle traces from unsteady CFD solutions is described. The system computes particle traces (streaklines) by integrating through the time steps. This system has been used by several NASA scientists to visualize their CFD time-dependent solutions. The flow visualization capabilities of this system are described, and visualization results are shown.

  14. Research Guides Mayo Clinic's Recruitment, Retention Efforts.

    ERIC Educational Resources Information Center

    Nayar, Veena R.; Morrey, Michael A.; Schneider, Kenneth J.; Purrington, Anne W.; Wilshusen, Laurie L.; Mullen, Michael P.; Seltman, Kent D.

    2001-01-01

    Discusses a collaborative study between Mayo Clinic's departments of human resources and marketing to identify the factors that influence candidates' decisions to accept or decline job offers and the reasons behind staff resignations. Study aimed to increase the effectiveness of employee recruitment advertising, streamline its interviewing…

  15. A Good Fit?

    ERIC Educational Resources Information Center

    Violino, Bob

    2010-01-01

    Outsourcing has evolved into a strategic imperative at a growing number of community colleges, especially as administrators rein in spending and streamline operations in the face of shrinking budgets. Across the country, more colleges are outsourcing a range of functions, including information technology (IT), course instruction, food service,…

  16. Ties That Bind

    ERIC Educational Resources Information Center

    Perkins, Thomas

    2012-01-01

    These are perilous times for community colleges. State and federal departments of education are pressing the nation's two-year career and technical colleges to be accountable while the colleges experience reductions in state funding and try to streamline services. That pressure is intensified by a growing national expectation that community…

  17. 77 FR 60039 - Non-Power Reactor License Renewal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-02

    ... NUCLEAR REGULATORY COMMISSION 10 CFR Part 50 [NRC-2011-0087] RIN 3150-AI96 Non-Power Reactor... the final regulatory basis for rulemaking to streamline non-power reactor license renewal. This final... Reactor (RTR) License Renewal Process. This contemplated rulemaking also recommends conforming changes to...

  18. Methodologies for Improving Flight Project Information Capture, Storage, and Dissemination

    NASA Technical Reports Server (NTRS)

    Equils, Douglas J.

    2011-01-01

    This paper will discuss the drawbacks and risks of the current documentation paradigm, how Document QuickStart improves on that process and ultimately how this stream-lined approach will reduce risk and costs to the next generation of Flight Projects at JPL

  19. Development of an online platform for streamlining highway LiDAR data collection, sharing, and processing.

    DOT National Transportation Integrated Search

    2016-12-01

    Lidar (a portmanteau of "light" and "radar.") is a remote sensing technology that measures distance by illuminating a target with a laser and analyzing the reflected light. Among other applications, lidar is particularly useful for detailed mapping o...

  20. HR, Streamlined

    ERIC Educational Resources Information Center

    Ramaswami, Rama

    2008-01-01

    Human Resources (HR) administrators are finding that as software modules are installed to automate various processes, they have more time to focus on strategic objectives. And as compliance with affirmative action and other employment regulations comes under increasing scrutiny, HR staffers are finding that software can deliver and track data with…

  1. 77 FR 76146 - Self-Regulatory Organizations; Municipal Securities Rulemaking Board; Order Approving a Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ...-Regulatory Organizations; Municipal Securities Rulemaking Board; Order Approving a Proposed Rule Change Consisting of Amendments To Streamline New Issue Information Submission Requirements Under MSRB Rules G-32..., and market information requirements); and the Electronic Municipal Market Access (``EMMA[supreg...

  2. Applicability of Zipper Merge Versus Early Merge in Kentucky Work Zones

    DOT National Transportation Integrated Search

    2017-12-24

    In an effort to improve work zone safety and streamline traffic flows, a number of state transportation agencies (STAs) have experimented with the zipper merge. The zipper merge differs from a conventional, or early, merge in that vehicles do not mer...

  3. Teaming. The Key to World Class Manufacturing.

    ERIC Educational Resources Information Center

    Wright, John R.

    1999-01-01

    Lean manufacturing, a streamlined system of flow and job shop techniques, relies on self-directed work teams. Technology educators can prepare students for work in this environment by using problem-solving teams in the classroom to work on design briefs and other group projects. (SK)

  4. A Streamlined Monitoring Framework for Low Impact Development Stormwater Management Practices - Cleveland

    EPA Science Inventory

    Suburban development surrounding extant urban cores provides watershed managers with two distinct scenarios. The first is abandonment of urban residential zones and problems associated with revitalization in areas where aquatic resources are in poor condition. The second is new d...

  5. Fact Sheet: EPCRA Guidance on Reporting Options for Sections 311 and 312 and Some Interpretations

    EPA Pesticide Factsheets

    The objective is to streamline the reporting requirements for facilities under sections 311 and 312 of the Emergency Planning and Community Right-to-Know Act, and provide state and local agencies with flexibility in implementing these sections.

  6. Integrated Pore-Water and Geophysical Investigations StreamlineCharacterization of Ground-Water Discharges to Surface Water

    EPA Science Inventory

    This issue of Technology News and Trends highlights strategies and tools for characterizing or monitoring remediation of sites with contaminated sediment. Addressing these sites often relies upon dynamic workplans that involve more efficient, cost-effective, and practical methods...

  7. SCREENING LIFE CYCLE ASSESSMENT OF GASOLINE ADDITIVES

    EPA Science Inventory

    The EPA's ORD is conducting a screening of Life Cycle Assessment (LCA) of selected automotive fuel (i.e., gasoline) systems. Although no specific guidelines exist on how to conduct such a streamlined approach, the basic idea is to use a mix of qualitative and quantitative generi...

  8. The Language of Library Leadership: Effective Communication.

    ERIC Educational Resources Information Center

    Hanson, Charles D.

    This paper examines the role of communication in library leadership. The discussion is organized into 14 sections: (1) multidimensional approaches to effective leadership communication and varying communication style to the situation; (2) the importance of conciseness; (3) streamlining library communication; (4) the vision being communicated by…

  9. 38 CFR 20.1500 - Rule 1500. Expedited Claims Adjudication Initiative.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Claims Adjudication Initiative. 20.1500 Section 20.1500 Pensions, Bonuses, and Veterans' Relief... Adjudication Initiative-Pilot Program § 20.1500 Rule 1500. Expedited Claims Adjudication Initiative. (a) Purpose. The Expedited Claims Adjudication Initiative is a pilot program designed to streamline the claims...

  10. 76 FR 49485 - Announcement of Requirements and Registration for “Lifeline Facebook App Challenge”

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... multidisciplinary teams of technology developers, entrepreneurs, and members of the disaster preparedness, response... application (app) that will provide actionable steps for Facebook users to increase their own personal... to increase personal preparedness, locate potential disaster victims, and streamline information...

  11. 78 FR 65674 - Agency Information Collection Activities: Proposed Collection: Public Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... will streamline the application submission process, enable an efficient award determination process... nursing and other qualified academic departments offering eligible advanced master's and/or doctoral degree nursing education programs that will prepare students to teach. Burden Statement: Burden in this...

  12. Social Security at the Crossroads.

    ERIC Educational Resources Information Center

    International Labour Review, 1980

    1980-01-01

    Social security schemes need to be streamlined and the underlying policies made more coherent to obtain the fullest possible return on expenditure. Third World countries need to reflect very seriously on the role of social security in the development process and on the management problems involved. (CT)

  13. Competencies in HRD. Symposium.

    ERIC Educational Resources Information Center

    2002

    This symposium is comprised of three papers on competencies in human resource development (HRD). "The Development of a Competency Model and Assessment Instrument for Public Sector Leadership and Management Development" (Sharon S. Naquin, Elwood F. Holton III) reports on a streamlined methodology and process used to develop a competency…

  14. Biological and Dose Thresholds for an Early Genomic Biomarker of Liver Carcinogenesis in Mice.

    EPA Science Inventory

    Traditional data sources for cancer risk assessment are resource-intensive, retrospective, and not feasible for the vast majority of environmental chemicals. The use of quantitative short-term genomic biomarkers may streamline this process by providing protective limits for known...

  15. Biological and Dose Thresholds for an Early Genomic Biomarker of Liver Carcinogenesis in Mice

    EPA Science Inventory

    Traditional data sources for cancer risk assessment are resource-intensive, retrospective, and not feasible for the vast majority of environmental chemicals. The use of quantitative short-term genomic biomarkers may streamline this process by providing protective limits for known...

  16. 76 FR 5328 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ...' Inputs. OMB Control Number: 0518-NEW. Summary of Collection: The Agricultural Research Service's (ARS.... ARS will conduct a farmer survey to collect information needed to streamline the diffusion of new farming systems technology developed by ARS scientists. The authority to collect this information is...

  17. UNIX Writer's Workbench: Software for Streamlined Communication.

    ERIC Educational Resources Information Center

    Frase, Lawrence T; Diel, Mary

    1986-01-01

    Discusses computer editing and describes the capacities and features of an integrated software package, Writer's Workbench. Suggests ways in which this program can be used to improve writing skills. Reviews the effects of this program on technical users, college students, and high school students. (ML)

  18. LPTA versus Tradeoff: Analysis of Contract Source Selection Strategies and Performance Outcomes

    DTIC Science & Technology

    2016-06-15

    methodologies contracting professionals employ to acquire what the DOD needs. Contracting professionals may use lowest price technically acceptable...17 1. 2. Lowest Price Technically Acceptable...Acquisition Streamlining Act Government Accountability Office highest technically rated offeror independent variable lowest price technically

  19. A LOTUS NOTES APPLICATION FOR PREPARING, REVIEWING, AND STORING NHEERL RESEARCH PROTOCOLS

    EPA Science Inventory

    Upon becoming QA Manager of the Health Effects Research Laboratory (HERL) in 1990, Ron became aware of the need to simplify and streamline the research planning process that Laboratory Principal Investigators (Pls) faced. Appropriately, animal studies require close scrutiny, both...

  20. 46 CFR 8.540 - Enrollment in SIP.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... GUARD, DEPARTMENT OF HOMELAND SECURITY PROCEDURES APPLICABLE TO THE PUBLIC VESSEL INSPECTION ALTERNATIVES Streamlined Inspection Program § 8.540 Enrollment in SIP. Upon successful completion of the training and evaluation phase, the Coast Guard SIP Advisor will recommend to the OCMI that the company or...

  1. 48 CFR 11.204 - Solicitation provisions and contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Commercial Item Descriptions, FPMR Part 101-29, in solicitations that cite specifications listed in the Index... Acquisition Streamlining and Standardization Information System (ASSIST), in solicitations that cite..., in solicitations that cite specifications that are not listed in the Index and are not furnished with...

  2. ADEQUACY OF VISUALLY CLASSIFIED PARTICLE COUNT STATISTICS FROM REGIONAL STREAM HABITAT SURVEYS

    EPA Science Inventory

    Streamlined sampling procedures must be used to achieve a sufficient sample size with limited resources in studies undertaken to evaluate habitat status and potential management-related habitat degradation at a regional scale. At the same time, these sampling procedures must achi...

  3. 77 FR 66523 - National Entrepreneurship Month, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... innovation, and get their ventures off the ground faster. Alongside it, leaders in the private sector... directed Federal agencies to streamline processes for establishing public-private research partnerships... into law, which is making it easier for innovative companies to go public and expand their workforce...

  4. 75 FR 73955 - Penalty Settlement Procedure

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ... 1977, or Mine Act. Hearings are held before the Commission's Administrative Law Judges, and appellate... Senate. The Commission is publishing a final rule to streamline the process for settling civil penalties... Commission's civil penalty settlement procedures. 75 FR 21987. The Commission explained that since 2006, the...

  5. Strategies of Successful Technology Integrators. Part I: Streamlining Classroom Management.

    ERIC Educational Resources Information Center

    McNally, Lynn; Etchison, Cindy

    2000-01-01

    Discussion of how to develop curriculum that successfully integrates technology into elementary and secondary school classrooms focuses on solutions for school and classroom management tasks. Highlights include Web-based solutions; student activities; word processing; desktop publishing; draw and paint programs; spreadsheets; and database…

  6. A Good Business Manager Can Save You Money.

    ERIC Educational Resources Information Center

    Nowakowski, Ben C.; Schneider, Robert

    1996-01-01

    Financially troubled districts could benefit by investing in a school business manager's salary. This article discusses how business managers can save districts money or increase revenue by streamlining cash management, fiscal accounting and reporting, financial planning and budgeting, grantsmanship, construction management, insurance and risk…

  7. Go8 Note: Student Visas

    ERIC Educational Resources Information Center

    Group of Eight (NJ1), 2012

    2012-01-01

    An independent review of the Australian student visa program was completed in 2011. Several of the recommendations from the review have been implemented by the Australian government, including the introduction of streamlined visa processing for applicants enrolled at an Australian university and increased flexibility in working conditions for…

  8. Computerized Manufacturing Automation. Employment, Education, and the Workplace. Summary.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Office of Technology Assessment.

    The application of programmable automation (PA) offers new opportunities to enhance and streamline manufacturing processes. Five PA technologies are examined in this report: computer-aided design, robots, numerically controlled machine tools, flexible manufacturing systems, and computer-integrated manufacturing. Each technology is in a relatively…

  9. 77 FR 14561 - Tribal Consultation Sessions-Administrative Organizational Assessment Draft Report...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-12

    ... DEPARTMENT OF THE INTERIOR Tribal Consultation Sessions--Administrative Organizational Assessment Draft Report, Organizational Streamlining of BIA and BIE, and BIE Topics AGENCY: Office of the Assistant...: the Administrative Organizational Assessment Draft Report on the organization of the AS-IA; ways to...

  10. Verify Module for Reporting A/C and Off-Cycle GHG Credits for Light-Duty Vehicle and Truck Manufacturers

    EPA Pesticide Factsheets

    This EPA presentation provides information on using the new Verify module, streamlining the process required to electronically submit annual reporting of air conditioning (A/C) and off-cycle GHG credits for light duty manufacturers.

  11. Response, Emergency Staging, Communications, Uniform Management, and Evacuation (R.E.S.C.U.M.E.) : concept of operations.

    DOT National Transportation Integrated Search

    1997-01-01

    The purpose of the Federal Highway Administration (FHWA)s mainstreaming program is to organize and manage the deployment of Intelligent Transportation Systems (ITS) for Commercial Vehicle Operations (CVO). ITS/CVO services are streamlining t...

  12. Streamlined ammonia removal from wastewater using biological deammonification process

    USDA-ARS?s Scientific Manuscript database

    In this work we evaluated biological deammonification process to more economically remove ammonia from livestock wastewater. The process combines partial nitritation (PN) and anammox. The anammox is a biologically mediated reaction that oxidizes ammonia (NH4+) and releases di-nitrogen gas (N2) unde...

  13. Mississippi Department of Transportation Research Division peer exchange II final report : September 24-26, 2002.

    DOT National Transportation Integrated Search

    2009-01-01

    A peer exchange can discuss general research management, or the agency can focus on certain parts of the research process. MDOT chose to focus on four themes: 1) Current Research Organization, 2) Identifying improvements That Streamline the Research ...

  14. A tool kit for evaluating electronic flight bags

    DOT National Transportation Integrated Search

    2006-09-01

    Over the past few years, the Volpe Center has developed a set of five tools that can be used to evaluate Electronic Flight Bags (EFBs) from a human factors perspective. The goal of these tools is to help streamline and standardize EFB human factors a...

  15. Streamlining the Acquisition Process: Should Program Directors be Granted Contracting Authority

    DTIC Science & Technology

    1989-09-01

    relationship between program directors and contracting officers contradicts basic management principles. One of Fayol’s principles of management is that...Franklin, Stephen G. Principles of Management , Eighth Edition. Homewood, II: Richard D. Irwin, Inc., 1982. Thybony, William W. Government Contracting based

  16. Sex differences in the relationship between planum temporale asymmetry and corpus callosum morphology in chimpanzees (Pan troglodytes): A combined MRI and DTI analysis.

    PubMed

    Hopkins, William D; Hopkins, Anna M; Misiura, Maria; Latash, Elitaveta M; Mareno, Mary Catherine; Schapiro, Steven J; Phillips, Kimberley A

    2016-12-01

    Increases brain size has been hypothesized to be inversely associated with the expression of behavioral and brain asymmetries within and between species. We tested this hypothesis by analyzing the relation between asymmetries in the planum temporale (PT) and different measures of the corpus callosum (CC) including surface area, streamline count as measured from diffusion tensor imaging, fractional anisotropy values and the ratio in the number of fibers to surface area in a sample of chimpanzees. We found that chimpanzees with larger PT asymmetries in absolute terms had smaller CC surface areas, fewer streamlines and a smaller ratio of fibers to surface area. These results were largely specific to male but not female chimpanzees. Our results partially support the hypothesis that brain asymmetries are linked to variation in corpus callosum morphology, although these associations may be sex-dependent. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Preheating of streamlined liner of pharyngeal airway (SLIPA) reduced the related complications: a randomized control study.

    PubMed

    Geng, Guiqi; Chen, Yingjie; Liu, Hailian

    2017-06-01

    This study was designed to verify whether preheating could decrease the complications that may be associated with the use of streamlined liner of pharyngeal airway (SLIPA). We evaluated the incidence of sore throat, maximum sealing pressure, hoarseness and blood stains after preheating of SLIPA. Eighty patients scheduled for hysteroscopic surgery to whom the SLIPA was considered suitable were randomly allocated to preheating group or control group. The SLIPA in preheating group was placed in the incubator at 42 °C. The control group temperature was 24 °C. The mean maximum sealing pressure and duration of insertion were compared. Patients were interviewed at recovery room about sore throat and other complications. There were statistical differences in incidence of sore throat, severity of sore throat and blood stains between groups. However there was no statistical difference in the maximum sealing pressure. Our results suggest preheating of the SLIPA decreased the complications related with the insertion of SLIPA. Clinical Trials.gov Identifier NCT02539485.

  18. 3D Visualization of Global Ocean Circulation

    NASA Astrophysics Data System (ADS)

    Nelson, V. G.; Sharma, R.; Zhang, E.; Schmittner, A.; Jenny, B.

    2015-12-01

    Advanced 3D visualization techniques are seldom used to explore the dynamic behavior of ocean circulation. Streamlines are an effective method for visualization of flow, and they can be designed to clearly show the dynamic behavior of a fluidic system. We employ vector field editing and extraction software to examine the topology of velocity vector fields generated by a 3D global circulation model coupled to a one-layer atmosphere model simulating preindustrial and last glacial maximum (LGM) conditions. This results in a streamline-based visualization along multiple density isosurfaces on which we visualize points of vertical exchange and the distribution of properties such as temperature and biogeochemical tracers. Previous work involving this model examined the change in the energetics driving overturning circulation and mixing between simulations of LGM and preindustrial conditions. This visualization elucidates the relationship between locations of vertical exchange and mixing, as well as demonstrates the effects of circulation and mixing on the distribution of tracers such as carbon isotopes.

  19. 78 FR 25137 - Radio Experimentation and Market Trials-Streamlining Rules

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-29

    ...This document revises and streamlines the Commission rules to modernize the Experimental Radio Service (ERS). The rules adopted in the Report and Order updates the ERS to a more flexible framework to keep pace with the speed of modern technological change while continuing to provide an environment where creativity can thrive. To accomplish this transition, the Commission created three new types of ERS licenses--the program license, the medical testing license, and the compliance testing license--to benefit the development of new technologies, expedite their introduction to the marketplace, and unleash the full power of innovators to keep the United States at the forefront of the communications industry. The Commission's actions also modify the market trial rules to eliminate confusion and more clearly articulate its policies with respect to marketing products prior to equipment certification. The Commission believes that these actions will remove regulatory barriers to experimentation, thereby permitting institutions to move from concept to experimentation to finished product more rapidly and to more quickly implement creative problem- solving methodologies.

  20. A streamlined artificial variable free version of simplex method.

    PubMed

    Inayatullah, Syed; Touheed, Nasir; Imtiaz, Muhammad

    2015-01-01

    This paper proposes a streamlined form of simplex method which provides some great benefits over traditional simplex method. For instance, it does not need any kind of artificial variables or artificial constraints; it could start with any feasible or infeasible basis of an LP. This method follows the same pivoting sequence as of simplex phase 1 without showing any explicit description of artificial variables which also makes it space efficient. Later in this paper, a dual version of the new method has also been presented which provides a way to easily implement the phase 1 of traditional dual simplex method. For a problem having an initial basis which is both primal and dual infeasible, our methods provide full freedom to the user, that whether to start with primal artificial free version or dual artificial free version without making any reformulation to the LP structure. Last but not the least, it provides a teaching aid for the teachers who want to teach feasibility achievement as a separate topic before teaching optimality achievement.

  1. A Streamlined Artificial Variable Free Version of Simplex Method

    PubMed Central

    Inayatullah, Syed; Touheed, Nasir; Imtiaz, Muhammad

    2015-01-01

    This paper proposes a streamlined form of simplex method which provides some great benefits over traditional simplex method. For instance, it does not need any kind of artificial variables or artificial constraints; it could start with any feasible or infeasible basis of an LP. This method follows the same pivoting sequence as of simplex phase 1 without showing any explicit description of artificial variables which also makes it space efficient. Later in this paper, a dual version of the new method has also been presented which provides a way to easily implement the phase 1 of traditional dual simplex method. For a problem having an initial basis which is both primal and dual infeasible, our methods provide full freedom to the user, that whether to start with primal artificial free version or dual artificial free version without making any reformulation to the LP structure. Last but not the least, it provides a teaching aid for the teachers who want to teach feasibility achievement as a separate topic before teaching optimality achievement. PMID:25767883

  2. Calculation of the flow field including boundary layer effects for supersonic mixed compression inlets at angles of attack

    NASA Technical Reports Server (NTRS)

    Vadyak, J.; Hoffman, J. D.

    1982-01-01

    The flow field in supersonic mixed compression aircraft inlets at angle of attack is calculated. A zonal modeling technique is employed to obtain the solution which divides the flow field into different computational regions. The computational regions consist of a supersonic core flow, boundary layer flows adjacent to both the forebody/centerbody and cowl contours, and flow in the shock wave boundary layer interaction regions. The zonal modeling analysis is described and some computational results are presented. The governing equations for the supersonic core flow form a hyperbolic system of partial differential equations. The equations for the characteristic surfaces and the compatibility equations applicable along these surfaces are derived. The characteristic surfaces are the stream surfaces, which are surfaces composed of streamlines, and the wave surfaces, which are surfaces tangent to a Mach conoid. The compatibility equations are expressed as directional derivatives along streamlines and bicharacteristics, which are the lines of tangency between a wave surface and a Mach conoid.

  3. Perspectives on Validation of High-Throughput Assays Supporting 21st Century Toxicity Testing1

    PubMed Central

    Judson, Richard; Kavlock, Robert; Martin, Matt; Reif, David; Houck, Keith; Knudsen, Thomas; Richard, Ann; Tice, Raymond R.; Whelan, Maurice; Xia, Menghang; Huang, Ruili; Austin, Christopher; Daston, George; Hartung, Thomas; Fowle, John R.; Wooge, William; Tong, Weida; Dix, David

    2014-01-01

    Summary In vitro, high-throughput screening (HTS) assays are seeing increasing use in toxicity testing. HTS assays can simultaneously test many chemicals, but have seen limited use in the regulatory arena, in part because of the need to undergo rigorous, time-consuming formal validation. Here we discuss streamlining the validation process, specifically for prioritization applications in which HTS assays are used to identify a high-concern subset of a collection of chemicals. The high-concern chemicals could then be tested sooner rather than later in standard guideline bioassays. The streamlined validation process would continue to ensure the reliability and relevance of assays for this application. We discuss the following practical guidelines: (1) follow current validation practice to the extent possible and practical; (2) make increased use of reference compounds to better demonstrate assay reliability and relevance; (3) deemphasize the need for cross-laboratory testing, and; (4) implement a web-based, transparent and expedited peer review process. PMID:23338806

  4. Streamlining and Standardizing Due Diligence to Ensure Quality of PV Power Plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kurtz, Sarah

    Those investing in PV power plants would like to have confidence that the plants will provide the anticipated return on investment. While due diligence is capably performed by independent engineers today, as PV systems mature, there will be benefit in standardization and streamlining of this process. The IECRE has defined technical information that is needed as a basis for each transaction step such as approving a design to begin construction, documenting readiness to operate, quantifying performance after a year of operation, and assessing the health of the plant in preparation for sale of the plant. The technical requirements have beenmore » defined by IEC Technical Committee 82 and have been designed to be both effective and efficient in completing the assessments. This workshop will describe these new tools that are now available to the community and will include a panel/audience discussion about how and when they can be most effectively used.« less

  5. Environmental process improvement feasibility study and demonstration program

    NASA Technical Reports Server (NTRS)

    Martin, Rodger L.

    1994-01-01

    This report is the final product of an environmental study conducted by Western Commercial Space Center, Inc. under contract to Tennessee-Calspan Center for Space Transportation and Applied Research. The purpose of this investigation is to accurately document the current environmental and permitting processes associated with commercial space launch activity at Vandenberg AFB, and make recommendations to streamline those processes. The particular areas of interest focus on: identifying applicable Federal, state, and local laws, Department of Defense directives, and Air force regulations; defining the environmental process on Vandenberg AFB and how it relates with other agencies, including Federal and state regulatory agencies; and defining the air quality permit process. Study investigation results are applied to an example Pilot Space Launch Vehicle (PSLV) planning to launch from Vandenberg AFB. The PSLV space hardware is analyzed with respect to environmental and permitting issues associated with vehicle processing, facilities required (existing or new), and launch. The PSLV verified the earlier findings of the study and gave insight into streamlining recommendations.

  6. The Robust Software Feedback Model: An Effective Waterfall Model Tailoring for Space SW

    NASA Astrophysics Data System (ADS)

    Tipaldi, Massimo; Gotz, Christoph; Ferraguto, Massimo; Troiano, Luigi; Bruenjes, Bernhard

    2013-08-01

    The selection of the most suitable software life cycle process is of paramount importance in any space SW project. Despite being the preferred choice, the waterfall model is often exposed to some criticism. As matter of fact, its main assumption of moving to a phase only when the preceding one is completed and perfected (and under the demanding SW schedule constraints) is not easily attainable. In this paper, a tailoring of the software waterfall model (named “Robust Software Feedback Model”) is presented. The proposed methodology sorts out these issues by combining a SW waterfall model with a SW prototyping approach. The former is aligned with the SW main production line and is based on the full ECSS-E-ST-40C life-cycle reviews, whereas the latter is carried out in advance versus the main SW streamline (so as to inject its lessons learnt into the main streamline) and is based on a lightweight approach.

  7. A second-order shock-adaptive Godunov scheme based on the generalized Lagrangian formulation

    NASA Astrophysics Data System (ADS)

    Lepage, Claude

    Application of the Godunov scheme to the Euler equations of gas dynamics, based on the Eulerian formulation of flow, smears discontinuities (especially sliplines) over several computational cells, while the accuracy in the smooth flow regions is of the order of a function of the cell width. Based on the generalized Lagrangian formulation (GLF), the Godunov scheme yields far superior results. By the use of coordinate streamlines in the GLF, the slipline (itself a streamline) is resolved crisply. Infinite shock resolution is achieved through the splitting of shock cells, while the accuracy in the smooth flow regions is improved using a nonconservative formulation of the governing equations coupled to a second order extension of the Godunov scheme. Furthermore, GLF requires no grid generation for boundary value problems and the simple structure of the solution to the Riemann problem in the GLF is exploited in the numerical implementation of the shock adaptive scheme. Numerical experiments reveal high efficiency and unprecedented resolution of shock and slipline discontinuities.

  8. PSA: A program to streamline orbit determination for launch support operations

    NASA Technical Reports Server (NTRS)

    Legerton, V. N.; Mottinger, N. A.

    1988-01-01

    An interactive, menu driven computer program was written to streamline the orbit determination process during the critical launch support phase of a mission. Residing on a virtual memory minicomputer, this program retains the quantities in-core needed to obtain a least squares estimate of the spacecraft trajectory with interactive displays to assist in rapid radio metric data evaluation. Menu-driven displays allow real time filter and data strategy development. Graphical and tabular displays can be sent to a laser printer for analysis without exiting the program. Products generated by this program feed back to the main orbit determination program in order to further refine the estimate of the trajectory. The final estimate provides a spacecraft ephemeris which is transmitted to the mission control center and used for antenna pointing and frequency predict generation by the Deep Space Network. The development and implementation process of this program differs from that used for most other navigation software by allowing the users to check important operating features during development and have changes made as needed.

  9. The flight of Ruellia ciliatiflora seeds

    NASA Astrophysics Data System (ADS)

    Cooper, Eric; Mosher, Molly; Whitaker, Dwight

    2017-11-01

    Fruits of Ruellia ciliatiflora explosively launch seeds at velocities over 10 m/s, reaching distances of over 7 m. Through high speed video analysis of the seeds' flight, we have observed high rates of backspin of up to 1660 Hz, one of the fastest known rotational rates in the natural world. Analytical calculations that model the torques on the seeds as those of a Rayleigh Disk and incorporate the effects of gravity of the seeds' angles of attack, show that the seeds' backspin orientation is stable under gyroscopic procession. This stable backspin orientation maintains a small area in direction of motion, decreasing drag force on the seeds and thus increasing dispersal distance. From careful analysis of high-speed video of the seeds' flight we experimentally determine the seeds' drag coefficients and find that they are consistent with drag predicted for the streamlined orientation. By using backspin to ensure a streamlined orientation, the seeds are able to reduce the energy costs for seed dispersal by up to a factor of ten.

  10. Flow field predictions for a slab delta wing at incidence

    NASA Technical Reports Server (NTRS)

    Conti, R. J.; Thomas, P. D.; Chou, Y. S.

    1972-01-01

    Theoretical results are presented for the structure of the hypersonic flow field of a blunt slab delta wing at moderately high angle of attack. Special attention is devoted to the interaction between the boundary layer and the inviscid entropy layer. The results are compared with experimental data. The three-dimensional inviscid flow is computed numerically by a marching finite difference method. Attention is concentrated on the windward side of the delta wing, where detailed comparisons are made with the data for shock shape and surface pressure distributions. Surface streamlines are generated, and used in the boundary layer analysis. The three-dimensional laminar boundary layer is computed numerically using a specially-developed technique based on small cross-flow in streamline coordinates. In the rear sections of the wing the boundary layer decreases drastically in the spanwise direction, so that it is still submerged in the entropy layer at the centerline, but surpasses it near the leading edge. Predicted heat transfer distributions are compared with experimental data.

  11. Establishment of a Multi-State Experiential Pharmacy Program Consortium

    PubMed Central

    Unterwagner, Whitney L.; Byrd, Debbie C.

    2008-01-01

    In 2002, a regional consortium was created for schools and colleges of pharmacy in Georgia and Alabama to assist experiential education faculty and staff members in streamlining administrative processes, providing required preceptor development, establishing a professional network, and conducting scholarly endeavors. Five schools and colleges of pharmacy with many shared experiential practice sites formed a consortium to help experiential faculty and staff members identify, discuss, and solve common experience program issues and challenges. During its 5 years in existence, the Southeastern Pharmacy Experiential Education Consortium has coordinated experiential schedules, developed and implemented uniform evaluation tools, coordinated site and preceptor development activities, established a work group for educational research and scholarship, and provided opportunities for networking and professional development. Several consortium members have received national recognition for their individual experiential education accomplishments. Through the activities of a regional consortium, members have successfully developed programs and initiatives that have streamlined administrative processes and have the potential to improve overall quality of experiential education programs. Professionally, consortium activities have resulted in 5 national presentations. PMID:18698386

  12. National Centers for Environmental Prediction

    Science.gov Websites

    Modeling Mesoscale Modeling Marine Modeling and Analysis Teams Climate Data Assimilation Ensembles and Post streamline the interaction of analysis, forecast, and post-processing systems within NCEP. The NEMS Force, and will eventually provide support to the community through the Developmental Test Center (DTC

  13. Benchmarking optimization software with COPS 3.0.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dolan, E. D.; More, J. J.; Munson, T. S.

    2004-05-24

    The authors describe version 3.0 of the COPS set of nonlinearly constrained optimization problems. They have added new problems, as well as streamlined and improved most of the problems. They also provide a comparison of the FILTER, KNITRO, LOQO, MINOS, and SNOPT solvers on these problems.

  14. 0-6758 : maintaining project consistency with transportation plans through the project life cycle with an emphasis on maintaining air quality conformity.

    DOT National Transportation Integrated Search

    2014-03-01

    Streamlined project delivery is a federally : mandated goal that the Texas Department of : Transportation (TxDOT) leadership supports to : achieve a more efficient and effective : transportation system in Texas. : Federal and state transportation pla...

  15. 76 FR 17071 - Amendment of the Commission's Rules Related to Retransmission Consent

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-28

    ... retransmission consent negotiations. The Commission believes that these rule changes could allow the market-based negotiations contemplated by the statute to proceed more smoothly, provide greater certainty to the negotiating... streamline and clarify our rules concerning or affecting retransmission consent negotiations. Our primary...

  16. Higher Education Regulations Study: Preliminary Findings

    ERIC Educational Resources Information Center

    Advisory Committee on Student Financial Assistance, 2011

    2011-01-01

    In the "Higher Education Opportunity Act" of 2008, Congress charged the Advisory Committee on Student Financial Assistance with conducting a review and analysis of regulations affecting higher education, to determine the extent to which regulations are overly burdensome and need to be streamlined, improved, or eliminated. Specifically,…

  17. Innovations in Site Characterization: Streamlining Cleanup at Vapor Intrusion and Product Removal Sites Using the Triad Approach: Hartford Plume Site, Hartford, Illinois

    EPA Pesticide Factsheets

    The Hartford Plume Site case study provides a detailed example of the strategies and technologies used at the site that are available to environmental practitioners to use at large and small hydrocarbon sites.

  18. Single-Reaction Multiplex Reverse Transcription PCR for Detection of Zika, Chikungunya, and Dengue Viruses

    PubMed Central

    Waggoner, Jesse J.; Gresh, Lionel; Mohamed-Hadley, Alisha; Ballesteros, Gabriela; Davila, Maria Jose Vargas; Tellez, Yolanda; Sahoo, Malaya K.; Balmaseda, Angel; Harris, Eva

    2016-01-01

    Clinical manifestations of Zika virus, chikungunya virus, and dengue virus infections can be similar. To improve virus detection, streamline molecular workflow, and decrease test costs, we developed and evaluated a multiplex real-time reverse transcription PCR for these viruses. PMID:27184629

  19. Health center streamlines use of audiovisual aids.

    PubMed

    Brantz, M H

    1978-09-01

    Audiovisual aids and programs can be used to help provide effective and efficient in-hospital continuing education programs. The cost of audiovisual equipment can be minimized and use can be maximized by implementing standardization policies that identify and simplify the number and types of equipment to be purchased.

  20. 76 FR 15859 - Reducing Regulatory Burden; Retrospective Review under E.O. 13563

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ... Management, at (202) 501- 1777. SUPPLEMENTARY INFORMATION: A. Background Executive Order 13563 directs each..., ineffective, insufficient, or excessively burdensome.'' The EO calls on every agency to develop ``a... modified, streamlined, expanded or repealed to make the agency's regulatory program more effective and or...

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